GORGO|Ensembl=ENSGGOG00000011192.3|UniProtKB=G3R6G1 G3R6G1 GOLT1A PTHR21493:SF245 CGI-141-RELATED/LIPASE CONTAINING PROTEIN VESICLE TRANSPORT PROTEIN GOT1A endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000016045.3|UniProtKB=G3RIY1 G3RIY1 ORAI2 PTHR31501:SF5 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 PROTEIN ORAI-2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000003040.3|UniProtKB=G3QKL5 G3QKL5 HNRNPA1 PTHR48026:SF2 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000044154.1|UniProtKB=G3QV73 G3QV73 PTHR15141:SF74 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN A2 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000025617.2|UniProtKB=G3RRD3 G3RRD3 PTHR46754:SF1 MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000006471.3|UniProtKB=G3QUD6 G3QUD6 MYBPC3 PTHR13817:SF20 TITIN MYOSIN-BINDING PROTEIN C, CARDIAC-TYPE structural molecule activity#GO:0005198 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;heart development#GO:0007507;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;muscle organ development#GO:0007517;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;developmental process#GO:0032502;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;animal organ morphogenesis#GO:0009887;heart morphogenesis#GO:0003007;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;system development#GO:0048731;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925 M band#GO:0031430;intracellular organelle#GO:0043229;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;A band#GO:0031672;contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000024741.2|UniProtKB=A0A2I2YYX0 A0A2I2YYX0 PTHR10394:SF12 40S RIBOSOMAL PROTEIN S8 SMALL RIBOSOMAL SUBUNIT PROTEIN ES8 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000012978.3|UniProtKB=Q69BK4 Q69BK4 UQCRFS1 PTHR10134:SF50 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333 catalytic complex#GO:1902494;respiratory chain complex III#GO:0045275;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007275.3|UniProtKB=G3QWG2 G3QWG2 NUDT17 PTHR42904:SF1 NUDIX HYDROLASE, NUDC SUBFAMILY M7GPPPN-MRNA HYDROLASE NUDT17 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;pyridine nucleotide catabolic process#GO:0019364;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000014685.3|UniProtKB=G3RFF9 G3RFF9 TFF2 PTHR13826:SF17 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 multicellular organismal-level homeostasis#GO:0048871;system process#GO:0003008;tissue homeostasis#GO:0001894;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;digestion#GO:0007586;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 CCKR signaling map#P06959>TFF2#G07264;CCKR signaling map#P06959>TFF2#G06971 GORGO|Ensembl=ENSGGOG00000006881.3|UniProtKB=G3QVH4 G3QVH4 LTA4H PTHR45726:SF7 LEUKOTRIENE A-4 HYDROLASE LEUKOTRIENE A-4 HYDROLASE peptidase activity#GO:0008233;ether hydrolase activity#GO:0016803;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177 peptide catabolic process#GO:0043171;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;icosanoid metabolic process#GO:0006690;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;peptide metabolic process#GO:0006518 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000004919.3|UniProtKB=G3QQF2 G3QQF2 RNF11 PTHR46359:SF1 GEO07743P1 RING FINGER PROTEIN 11 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000001806.3|UniProtKB=G3QHF2 G3QHF2 C4H17orf67 PTHR48415:SF1 GENE 525-RELATED C17ORF67 HOMOLOG GORGO|Ensembl=ENSGGOG00000022655.2|UniProtKB=G3SB76 G3SB76 TUBB PTHR11588:SF61 TUBULIN TUBULIN BETA CHAIN structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630 tubulin#PC00228;cytoskeletal protein#PC00085 Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780 GORGO|Ensembl=ENSGGOG00000039154.1|UniProtKB=A0A2I2YAC4 A0A2I2YAC4 PTHR10501:SF86 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B RRM DOMAIN-CONTAINING PROTEIN snRNA binding#GO:0017069;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000013613.3|UniProtKB=G3RCP8 G3RCP8 KAZN PTHR12776:SF1 KAZRIN-RELATED KAZRIN GORGO|Ensembl=ENSGGOG00000015656.3|UniProtKB=G3RHZ1 G3RHZ1 ZNF581 PTHR24390:SF76 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 581 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000014991.3|UniProtKB=A0A2I2YXY9 A0A2I2YXY9 MARCHF8 PTHR45981:SF4 LD02310P E3 UBIQUITIN-PROTEIN LIGASE MARCHF8 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;MHC protein binding#GO:0042287;binding#GO:0005488;signaling receptor binding#GO:0005102;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;immune response#GO:0006955;cellular process#GO:0009987;antigen processing and presentation#GO:0019882;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376;response to stimulus#GO:0050896;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211 early endosome membrane#GO:0031901;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000009250.3|UniProtKB=G3R1H2 G3R1H2 NR6A1 PTHR48092:SF18 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 6 GROUP A MEMBER 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000038767.1|UniProtKB=G3QM76 G3QM76 LOC101152713 PTHR26454:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C4 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015466.3|UniProtKB=G3RHG7 G3RHG7 ARSF PTHR42693:SF2 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE F hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000011707.3|UniProtKB=G3RPI6 G3RPI6 COPS7B PTHR15350:SF8 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 SIGNALOSOME COMPLEX SUBUNIT 7B protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;post-translational protein modification#GO:0043687 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000002312.3|UniProtKB=G3QIR0 G3QIR0 CDK2 PTHR24056:SF521 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular response to stress#GO:0033554;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;signal transduction#GO:0007165;cell communication#GO:0007154;telomere organization#GO:0032200;mitotic cell cycle phase transition#GO:0044772;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;DNA damage response#GO:0006974;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139 membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway#P00059>Cdc2#P04634;p53 pathway#P00059>Cdk2#P04625;p53 pathway feedback loops 2#P04398>cdk2#P04653 GORGO|Ensembl=ENSGGOG00000041232.1|UniProtKB=A0A2I2YDH7 A0A2I2YDH7 LOC101144552 PTHR45965:SF4 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 1 regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of protein secretion#GO:0050708;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000028574.2|UniProtKB=G3RYS5 G3RYS5 FUT10 PTHR11929:SF194 ALPHA- 1,3 -FUCOSYLTRANSFERASE GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 3 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000009216.3|UniProtKB=G3RTX8 G3RTX8 NSRP1 PTHR31938:SF4 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 GORGO|Ensembl=ENSGGOG00000011562.3|UniProtKB=G3R7E9 G3R7E9 SART3 PTHR15481:SF5 RIBONUCLEIC ACID BINDING PROTEIN S1 SPLICEOSOME ASSOCIATED FACTOR 3, U4_U6 RECYCLING PROTEIN RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000039516.1|UniProtKB=A0A2I2YDT2 A0A2I2YDT2 LOC109025355 PTHR26453:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13H1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013689.3|UniProtKB=G3RCX2 G3RCX2 PDE5A PTHR11347:SF20 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 hydrolase#PC00121;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000006712.3|UniProtKB=A0A2I2Z5Z9 A0A2I2Z5Z9 SP100 PTHR46386:SF15 NUCLEAR BODY PROTEIN SP140 NUCLEAR AUTOANTIGEN SP-100 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001014.3|UniProtKB=G3QFD4 G3QFD4 FMN2 PTHR13037:SF16 FORMIN FORMIN-2 protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;endomembrane system#GO:0012505;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;endoplasmic reticulum#GO:0005783;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 GORGO|Ensembl=ENSGGOG00000024801.2|UniProtKB=G3S2V5 G3S2V5 LOC101154433 PTHR10334:SF521 CYSTEINE-RICH SECRETORY PROTEIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 18 MEMBER A-RELATED polysaccharide binding#GO:0030247;binding#GO:0005488;carbohydrate binding#GO:0030246 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000012586.3|UniProtKB=G3S7S8 G3S7S8 FBF1 PTHR33689:SF1 FAS-BINDING FACTOR 1 FAS-BINDING FACTOR 1 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 centriole#GO:0005814;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000044133.1|UniProtKB=A0A2I2ZKR2 A0A2I2ZKR2 PTHR45935:SF26 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN SCAND2P-RELATED GORGO|Ensembl=ENSGGOG00000016383.3|UniProtKB=G3RJT5 G3RJT5 RELL2 PTHR31481:SF0 RELT-LIKE PROTEIN 2 RELL2 RELT-LIKE PROTEIN 2 regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell-substrate adhesion#GO:0010810;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 GORGO|Ensembl=ENSGGOG00000009365.3|UniProtKB=G3R1S6 G3R1S6 PIK3CA PTHR10048:SF107 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742 organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;glycerophospholipid metabolic process#GO:0006650;intracellular signaling cassette#GO:0141124;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;cell motility#GO:0048870;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622 kinase#PC00137 Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;p53 pathway feedback loops 2#P04398>P110alpha#P04657;p53 pathway feedback loops 2#P04398>P110ALPHA#G04707;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>P110alpha#P04633;PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;Ras Pathway#P04393>PI3K#P04567;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;Interleukin signaling pathway#P00036>PI3K#P00990;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>p110alpha#G04694;PI3 kinase pathway#P00048>P110ACT#P01177;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>p110alpha#G04676;VEGF signaling pathway#P00056>PI3K#P01413;PI3 kinase pathway#P00048>p110#P01192;FGF signaling pathway#P00021>PI3K#P00640;B cell activation#P00010>PI3K#P00391;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;T cell activation#P00053>PI3K#P01322;EGF receptor signaling pathway#P00018>PI3K#P00557;Angiogenesis#P00005>PI3K#P00236;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>P110alpha#P04498 GORGO|Ensembl=ENSGGOG00000037078.1|UniProtKB=A0A2I2Z970 A0A2I2Z970 INSL3 PTHR10423:SF5 INSULIN-LIKE 3 JANUS KINASE 3 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of reproductive process#GO:2000241;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000011470.2|UniProtKB=G3R754 G3R754 NR2F1 PTHR24083:SF168 NUCLEAR HORMONE RECEPTOR COUP TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000005792.3|UniProtKB=G3QSN2 G3QSN2 GALNT12 PTHR11675:SF18 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 12 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000005921.3|UniProtKB=G3QSZ4 G3QSZ4 C1H1orf162 PTHR37997:SF1 TRANSMEMBRANE PROTEIN C1ORF162 TRANSMEMBRANE PROTEIN C1ORF162 GORGO|Ensembl=ENSGGOG00000039514.1|UniProtKB=A0A2I2ZPC5 A0A2I2ZPC5 SFTPB PTHR11480:SF33 SAPOSIN-RELATED PULMONARY SURFACTANT-ASSOCIATED PROTEIN B cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;late endosome#GO:0005770;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003686.3|UniProtKB=G3QM88 G3QM88 ZNF705A PTHR24381:SF303 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 705A-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000008225.3|UniProtKB=G3QYU6 G3QYU6 PTHR22012:SF2 FIBROUS SHEATH INTERACTING PROTEIN 1 FIBROUS SHEATH-INTERACTING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000008759.3|UniProtKB=G3RR94 G3RR94 PTHR35068:SF1 BEN DOMAIN-CONTAINING PROTEIN 7 BEN DOMAIN-CONTAINING PROTEIN 7 response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;signaling#GO:0023052;hemostasis#GO:0007599;regulation of biological process#GO:0050789;cell communication#GO:0007154;wound healing#GO:0042060;regulation of biological quality#GO:0065008;immune system process#GO:0002376;cell activation#GO:0001775;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;response to wounding#GO:0009611;response to stress#GO:0006950;immune response#GO:0006955;coagulation#GO:0050817;cellular process#GO:0009987;platelet activation#GO:0030168;blood coagulation#GO:0007596 GORGO|Ensembl=ENSGGOG00000007447.3|UniProtKB=A0A2I2YLY3 A0A2I2YLY3 CUL3 PTHR11932:SF180 CULLIN CULLIN-3 binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002828.3|UniProtKB=G3QK22 G3QK22 MANSC4 PTHR46750:SF2 KUNITZ-TYPE PROTEASE INHIBITOR 1 MANSC DOMAIN-CONTAINING PROTEIN 4 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;epidermis development#GO:0008544;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;epithelium development#GO:0060429;tissue development#GO:0009888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000005508.3|UniProtKB=G3QRY0 G3QRY0 PDXDC1 PTHR42735:SF1 FAMILY NOT NAMED PYRIDOXAL-DEPENDENT DECARBOXYLASE DOMAIN-CONTAINING PROTEIN 1-RELATED carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000004927.3|UniProtKB=G3QQG1 G3QQG1 EFCAB11 PTHR23064:SF72 TROPONIN TROPONIN C, SKELETAL MUSCLE actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000002506.3|UniProtKB=G3QJ83 G3QJ83 LOC129526754 PTHR48002:SF139 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K13 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000042851.1|UniProtKB=A0A2I2ZUK4 A0A2I2ZUK4 PTHR11193:SF8 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000000663.3|UniProtKB=G3QEF7 G3QEF7 SALL1 PTHR23233:SF51 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000043263.1|UniProtKB=A0A2I2Y936 A0A2I2Y936 FXYD7 PTHR14132:SF1 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 7 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of monoatomic ion transmembrane transport#GO:0034765;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013883.3|UniProtKB=G3RDD6 G3RDD6 NRN1L PTHR15902:SF2 NEURITIN-RELATED NEURITIN-LIKE PROTEIN cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;developmental cell growth#GO:0048588;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;developmental growth involved in morphogenesis#GO:0060560;neuron projection extension#GO:1990138;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental growth#GO:0048589;cell growth#GO:0016049;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;neuron projection morphogenesis#GO:0048812 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000014307.3|UniProtKB=G3REG1 G3REG1 OR4D5 PTHR26453:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008205.3|UniProtKB=A0A2I2ZJP4 A0A2I2ZJP4 PTHR45994:SF3 FI21225P1 PROTEIN UNC-45 HOMOLOG A protein binding#GO:0005515;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;binding#GO:0005488 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000010288.3|UniProtKB=G3R449 G3R449 ZNF652 PTHR24393:SF18 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 652 transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000010442.3|UniProtKB=G3R4I1 G3R4I1 F2R PTHR24232:SF20 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of coagulation#GO:0050818;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of response to wounding#GO:1903034;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of hemostasis#GO:1900046;cellular process#GO:0009987;cell communication#GO:0007154;regulation of biological quality#GO:0065008;positive regulation of coagulation#GO:0050820;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to stimulus#GO:0050896;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of wound healing#GO:0061041;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Angiogenesis#P00005>PAR#P00192;Blood coagulation#P00011>PAR-1#P00404 GORGO|Ensembl=ENSGGOG00000000914.3|UniProtKB=G3QF41 G3QF41 FCGBP PTHR11339:SF373 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED IGGFC-BINDING PROTEIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000012164.3|UniProtKB=G3R8Z6 G3R8Z6 PSMB7 PTHR11599:SF42 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-7 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000010784.3|UniProtKB=G3R5F2 G3R5F2 MBTPS1 PTHR43806:SF7 PEPTIDASE S8 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-1 PROTEASE hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000038046.1|UniProtKB=G3RSJ4 G3RSJ4 LOC101128980 PTHR13999:SF4 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 3 cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to virus#GO:0009615;cell communication#GO:0007154;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;response to peptide#GO:1901652;response to type II interferon#GO:0034341;cellular process#GO:0009987;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000026482.2|UniProtKB=G3SDB5 G3SDB5 YARS2 PTHR11766:SF0 TYROSYL-TRNA SYNTHETASE TYROSINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000004297.3|UniProtKB=G3QNU0 G3QNU0 TPBG PTHR24364:SF17 LP06937P TROPHOBLAST GLYCOPROTEIN regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008277.3|UniProtKB=G3RZI5 G3RZI5 RAB38 PTHR24073:SF839 DRAB5-RELATED RAS-RELATED PROTEIN RAB-38 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 macromolecule localization#GO:0033036;developmental pigmentation#GO:0048066;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;developmental maturation#GO:0021700;cellular pigmentation#GO:0033059;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;intracellular protein localization#GO:0008104;cellular response to stimulus#GO:0051716;cell differentiation#GO:0030154;response to stimulus#GO:0050896;pigmentation#GO:0043473;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus#GO:0005794;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;melanosome#GO:0042470;cytoplasm#GO:0005737;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000014587.3|UniProtKB=G3RF77 G3RF77 VARS2 PTHR11946:SF71 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000016067.3|UniProtKB=Q2IBF1 Q2IBF1 TES PTHR24211:SF1 LIM DOMAIN-CONTAINING PROTEIN TESTIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000042120.1|UniProtKB=A0A2I2Z6S6 A0A2I2Z6S6 LOC109024120 PTHR31943:SF17 INTERLEUKIN-28 AND 29 INTERFERON LAMBDA-4 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 immune system process#GO:0002376;response to virus#GO:0009615;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;defense response to virus#GO:0051607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000022405.2|UniProtKB=A0A2I2ZDE5 A0A2I2ZDE5 PTHR11760:SF38 30S/40S RIBOSOMAL PROTEIN S3 SMALL RIBOSOMAL SUBUNIT PROTEIN US3 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of apoptotic process#GO:0043065;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of programmed cell death#GO:0043068 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014572.3|UniProtKB=G3RQA0 G3RQA0 PXDNL PTHR11475:SF38 OXIDASE/PEROXIDASE OXIDOREDUCTASE PXDNL-RELATED catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 GORGO|Ensembl=ENSGGOG00000013257.3|UniProtKB=G3RSZ5 G3RSZ5 NT5C2 PTHR12103:SF17 5'-NUCLEOTIDASE DOMAIN-CONTAINING CYTOSOLIC PURINE 5'-NUCLEOTIDASE phosphoric ester hydrolase activity#GO:0042578;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidase activity#GO:0008252;kinase activity#GO:0016301;phosphatase activity#GO:0016791;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;nucleobase-containing compound kinase activity#GO:0019205;5'-nucleotidase activity#GO:0008253 ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;IMP metabolic process#GO:0046040;nucleoside phosphate catabolic process#GO:1901292;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000039925.1|UniProtKB=A0A2I2YC68 A0A2I2YC68 PTHR10709:SF19 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1A organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cortical actin cytoskeleton organization#GO:0030866;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000002175.3|UniProtKB=G3RSM6 G3RSM6 PPA2 PTHR10286:SF49 INORGANIC PYROPHOSPHATASE INORGANIC PYROPHOSPHATASE 2, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 pyrophosphatase#PC00196 GORGO|Ensembl=ENSGGOG00000010313.3|UniProtKB=A0A2I2ZVU8 A0A2I2ZVU8 TJP2 PTHR13865:SF26 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN 2 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 anatomical structure development#GO:0048856;localization#GO:0051179;regulation of biological quality#GO:0065008;tissue homeostasis#GO:0001894;animal gross anatomical part developmental process#GO:0160108;circulatory system process#GO:0003013;protein localization to cell junction#GO:1902414;cell adhesion#GO:0007155;cell junction organization#GO:0034330;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organismal-level homeostasis#GO:0048871;system process#GO:0003008;intracellular protein localization#GO:0008104;cell-cell junction organization#GO:0045216;endothelial cell differentiation#GO:0045446;developmental process#GO:0032502;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;tissue development#GO:0009888;blood circulation#GO:0008015;epithelium development#GO:0060429;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;macromolecule localization#GO:0033036;cellular process#GO:0009987 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000003096.3|UniProtKB=A0A2I2YMQ3 A0A2I2YMQ3 PTHR11931:SF15 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE 1 intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868;phosphoglycerate mutase activity#GO:0004619;isomerase activity#GO:0016853 nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 mutase#PC00160;isomerase#PC00135 Glycolysis#P00024>Phosphoglyceromutase#P00680 GORGO|Ensembl=ENSGGOG00000010907.3|UniProtKB=G3R5P8 G3R5P8 STK16 PTHR45998:SF9 SERINE/THREONINE-PROTEIN KINASE 16 SERINE_THREONINE-PROTEIN KINASE 16 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000015856.3|UniProtKB=G3RIG0 G3RIG0 KLHL22 PTHR45632:SF5 LD33804P KELCH-LIKE PROTEIN 22 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016307.3|UniProtKB=G3RRN4 G3RRN4 LOC115930107 PTHR14112:SF19 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX3 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000016214.3|UniProtKB=G3SD56 G3SD56 VPS28 PTHR12937:SF0 VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;cellular localization#GO:0051641;protein transport#GO:0015031;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment of protein localization to vacuole#GO:0072666;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;endosomal transport#GO:0016197;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle membrane#GO:0012506;cytosol#GO:0005829;ESCRT I complex#GO:0000813;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000010910.3|UniProtKB=G3R5Q2 G3R5Q2 SLC25A44 PTHR46314:SF2 SOLUTE CARRIER FAMILY 25 MEMBER 44 SOLUTE CARRIER FAMILY 25 MEMBER 44 transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;branched-chain amino acid transmembrane transporter activity#GO:0015658 transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;nitrogen compound transport#GO:0071705;branched-chain amino acid transport#GO:0015803;establishment of localization#GO:0051234;localization#GO:0051179 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015008.3|UniProtKB=G3RGA6 G3RGA6 LIFR PTHR23036:SF105 CYTOKINE RECEPTOR LEUKEMIA INHIBITORY FACTOR RECEPTOR cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to peptide#GO:1901652;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell population proliferation#GO:0008284 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027560.2|UniProtKB=G3SH69 G3SH69 CGA PTHR11509:SF0 GLYCOPROTEIN HORMONE ALPHA CHAIN GLYCOPROTEIN HORMONES ALPHA CHAIN signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 intercellular signal molecule#PC00207;peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Thyrotropin#P04588;Gonadotropin-releasing hormone receptor pathway#P06664>CGA#G06886;Gonadotropin-releasing hormone receptor pathway#P06664>CGA#G06673;Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585;Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586 GORGO|Ensembl=ENSGGOG00000016934.3|UniProtKB=G3RL89 G3RL89 PTHR13167:SF24 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 2 gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 detection of mechanical stimulus#GO:0050982;regulation of biological quality#GO:0065008;response to external stimulus#GO:0009605;regulation of membrane potential#GO:0042391;cellular response to abiotic stimulus#GO:0071214;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;biological regulation#GO:0065007;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000043150.1|UniProtKB=A0A2I2ZD39 A0A2I2ZD39 PTHR21304:SF6 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000036286.1|UniProtKB=A0A2I2YHC9 A0A2I2YHC9 LOC109024886 PTHR23428:SF160 HISTONE H2B HISTONE H2B TYPE 1-H antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000043810.1|UniProtKB=G3SIC4 G3SIC4 EIF4E2 PTHR11960:SF17 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2 translation factor activity#GO:0180051;nucleic acid binding#GO:0003676;binding#GO:0005488;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000039522.1|UniProtKB=A0A2I2YZA7 A0A2I2YZA7 PTHR24320:SF264 RETINOL DEHYDROGENASE POLYPRENOL DEHYDROGENASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007706.3|UniProtKB=G3QXJ4 G3QXJ4 MYORG PTHR43053:SF8 GLYCOSIDASE FAMILY 31 ALPHA-GALACTOSIDASE MYORG muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;cell development#GO:0048468;muscle structure development#GO:0061061;cell differentiation#GO:0030154;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;cellular developmental process#GO:0048869;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;muscle organ development#GO:0007517;tissue development#GO:0009888;skeletal muscle tissue development#GO:0007519;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;glucosidase#PC00108 GORGO|Ensembl=ENSGGOG00000007347.3|UniProtKB=G3QWM9 G3QWM9 MICOS10 PTHR21304:SF5 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000006539.3|UniProtKB=G3QUJ7 G3QUJ7 ARMH3 PTHR13608:SF3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000012141.3|UniProtKB=G3R8X4 G3R8X4 VRK2 PTHR11909:SF100 CASEIN KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE VRK2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;response to stress#GO:0006950;cell communication#GO:0007154;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000007175.3|UniProtKB=A0A2I2Y210 A0A2I2Y210 CASTOR1 PTHR31131:SF3 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 1 organic acid binding#GO:0043177;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;cation binding#GO:0043169;amino acid binding#GO:0016597 regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;response to nitrogen compound#GO:1901698;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;cellular response to oxygen-containing compound#GO:1901701;response to acid chemical#GO:0001101;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007768.3|UniProtKB=G3QXP8 G3QXP8 TNFRSF1B PTHR47386:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1B transmembrane signaling receptor activity#GO:0004888;death receptor activity#GO:0005035;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515;tumor necrosis factor binding#GO:0043120;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of lymphocyte proliferation#GO:0050670;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;positive regulation of developmental process#GO:0051094;regulation of system process#GO:0044057;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of inflammatory response#GO:0050728;regulation of T cell proliferation#GO:0042129;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;programmed cell death#GO:0012501;regulation of immune effector process#GO:0002697;regulation of cell population proliferation#GO:0042127;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;positive regulation of cell development#GO:0010720;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of mononuclear cell proliferation#GO:0032944;regulation of leukocyte proliferation#GO:0070663;positive regulation of cell differentiation#GO:0045597;regulation of proteolysis#GO:0030162;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;positive regulation of multicellular organismal process#GO:0051240;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cytokine production involved in immune response#GO:0002718;regulation of lymphocyte mediated immunity#GO:0002706;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;apoptotic signaling pathway#GO:0097190;regulation of response to stress#GO:0080134;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;negative regulation of defense response#GO:0031348;cell death#GO:0008219;regulation of leukocyte mediated immunity#GO:0002703;regulation of protein catabolic process#GO:0042176;intracellular signal transduction#GO:0035556;positive regulation of protein catabolic process#GO:0045732;regulation of nervous system development#GO:0051960;cell communication#GO:0007154;regulation of inflammatory response#GO:0050727;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;regulation of T cell activation#GO:0050863;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cell surface receptor signaling pathway#GO:0007166;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;positive regulation of nervous system development#GO:0051962;regulation of multicellular organismal development#GO:2000026;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;intrinsic apoptotic signaling pathway#GO:0097193;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;cellular response to stress#GO:0033554 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TNFR2#P00287 GORGO|Ensembl=ENSGGOG00000002265.3|UniProtKB=G3QIL8 G3QIL8 NELFE PTHR17250:SF0 NEGATIVE ELONGATION FACTOR E NEGATIVE ELONGATION FACTOR E biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000014987.3|UniProtKB=G3RG85 G3RG85 RNF8 PTHR15067:SF9 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE RNF8 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;histone binding#GO:0042393;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;DNA repair#GO:0006281;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000013007.3|UniProtKB=G3RB51 G3RB51 LENG1 PTHR22093:SF0 LEUKOCYTE RECEPTOR CLUSTER LRC MEMBER 1 LEUKOCYTE RECEPTOR CLUSTER MEMBER 1 GORGO|Ensembl=ENSGGOG00000013685.3|UniProtKB=G3RCW4 G3RCW4 GPKOW PTHR15818:SF2 G PATCH AND KOW-CONTAINING G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000000424.4|UniProtKB=G3QDU7 G3QDU7 COL24A1 PTHR24023:SF987 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXIV) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000038928.1|UniProtKB=A0A2I2YYS3 A0A2I2YYS3 PTHR20903:SF2 PREFOLDIN SUBUNIT 1-RELATED PREFOLDIN SUBUNIT 1 biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000036781.1|UniProtKB=A0A2I2YQE8 A0A2I2YQE8 C1QTNF6 PTHR22923:SF70 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011245.3|UniProtKB=G3R6K4 G3R6K4 IGLON5 PTHR42757:SF12 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED IGLON FAMILY MEMBER 5 regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;cell adhesion#GO:0007155;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;regulation of biological process#GO:0050789;cell-cell adhesion#GO:0098609;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000000474.3|UniProtKB=A0A2I2ZQ30 A0A2I2ZQ30 STIM2 PTHR15136:SF2 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE 2 ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;molecular function regulator activity#GO:0098772;calcium ion binding#GO:0005509;transporter regulator activity#GO:0141108;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;channel regulator activity#GO:0016247;metal ion binding#GO:0046872 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;monoatomic ion homeostasis#GO:0050801 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000039348.1|UniProtKB=A0A2I2ZVZ3 A0A2I2ZVZ3 PTHR12758:SF21 APOPTOSIS INHIBITOR 5-RELATED APOPTOSIS INHIBITOR 5 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000015010.3|UniProtKB=G3RGB3 G3RGB3 FN1 PTHR46708:SF8 TENASCIN FIBRONECTIN integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102;carbohydrate derivative binding#GO:0097367 cellular component organization#GO:0016043;cell-substrate junction assembly#GO:0007044;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;system development#GO:0048731;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell-substrate junction organization#GO:0150115;developmental process#GO:0032502;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Fibronectin#P00939 GORGO|Ensembl=ENSGGOG00000010623.3|UniProtKB=G3R4Y9 G3R4Y9 AMIGO3 PTHR24368:SF62 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 3 multicellular organismal process#GO:0032501;brain development#GO:0007420;central nervous system development#GO:0007417;nervous system development#GO:0007399;head development#GO:0060322;cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000016291.3|UniProtKB=G3RJK6 G3RJK6 EIF3B PTHR14068:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000041443.1|UniProtKB=A0A2I2Z6L8 A0A2I2Z6L8 PTHR10623:SF20 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;supramolecular fiber#GO:0099512;microtubule#GO:0005874;microtubule end#GO:1990752;cytoplasmic microtubule#GO:0005881;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000042265.1|UniProtKB=A0A2I2ZHB4 A0A2I2ZHB4 PTHR46131:SF2 SD08549P MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER SLC25A51-RELATED nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;purine nucleotide transmembrane transporter activity#GO:0015216;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000037173.1|UniProtKB=G3QS49 G3QS49 SOX7 PTHR10270:SF210 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-7 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000027043.2|UniProtKB=G3S091 G3S091 PTHR11599:SF16 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-2 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 peptidase complex#GO:1905368;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;proteasome complex#GO:0000502 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000024711.2|UniProtKB=G3S526 G3S526 LOC101133845 PTHR26453:SF88 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012208.3|UniProtKB=A0A2I2Z4X6 A0A2I2Z4X6 NAMPT PTHR43816:SF1 NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000041098.1|UniProtKB=A0A2I2Z2P7 A0A2I2Z2P7 PTHR48068:SF6 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TAF9B structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004 intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;peptidase complex#GO:1905368;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;transferase complex#GO:1990234;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000009170.3|UniProtKB=A0A2I2Y9H5 A0A2I2Y9H5 ENO3 PTHR11902:SF5 ENOLASE BETA-ENOLASE catalytic activity#GO:0003824;phosphopyruvate hydratase activity#GO:0004634;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;cytosol#GO:0005829 lyase#PC00144;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003621.3|UniProtKB=G3QM33 G3QM33 PTHR37860:SF2 AGAP008810-PA PROTEIN APOLTP GORGO|Ensembl=ENSGGOG00000015119.3|UniProtKB=A0A2I2ZXL2 A0A2I2ZXL2 BUD31 PTHR19411:SF0 PROTEIN BUD31-RELATED PROTEIN BUD31 HOMOLOG nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000013582.3|UniProtKB=G3RQM3 G3RQM3 LOC109023678 PTHR23299:SF22 METALLOTHIONEIN METALLOTHIONEIN-1G metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular response to chemical stimulus#GO:0070887;inorganic ion homeostasis#GO:0098771;intracellular monoatomic ion homeostasis#GO:0006873;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;homeostatic process#GO:0042592;response to cadmium ion#GO:0046686;response to metal ion#GO:0010038;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;detoxification of inorganic compound#GO:0061687;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;response to chemical#GO:0042221;detoxification#GO:0098754 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000040312.1|UniProtKB=A0A2I2ZKG0 A0A2I2ZKG0 PTHR19970:SF34 RIBOSOMAL PROTEIN L39E RIBOSOMAL PROTEIN L39 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005280.3|UniProtKB=G3QRC6 G3QRC6 CCL25 PTHR12015:SF70 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 25 signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;chemokine-mediated signaling pathway#GO:0070098;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cell migration#GO:0016477;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of cell motility#GO:2000147;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;taxis#GO:0042330;response to chemical#GO:0042221;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cellular process#GO:0009987;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000027360.2|UniProtKB=A0A2I2ZVX2 A0A2I2ZVX2 PTHR46029:SF6 C-TERMINAL-BINDING PROTEIN D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000024216.2|UniProtKB=G3RXV8 G3RXV8 TPST1 PTHR12788:SF4 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220 CCKR signaling map#P06959>Protein tyrosine sulfotransferase#P07148 GORGO|Ensembl=ENSGGOG00000044068.1|UniProtKB=A0A2I2ZAI4 A0A2I2ZAI4 CCL11 PTHR12015:SF146 SMALL INDUCIBLE CYTOKINE A EOTAXIN cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;regulation of cell motility#GO:2000145;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;cell migration#GO:0016477;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell motility#GO:2000147;response to peptide#GO:1901652;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;response to cytokine#GO:0034097;taxis#GO:0042330;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cell surface receptor signaling pathway#GO:0007166;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000024603.2|UniProtKB=A0A2I2Z487 A0A2I2Z487 PTHR31526:SF4 SOSS COMPLEX SUBUNIT C SOSS COMPLEX SUBUNIT C cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000023101.2|UniProtKB=G3RRS1 G3RRS1 STEAP2 PTHR14239:SF12 DUDULIN-RELATED STEAP2 METALLOREDUCTASE catalytic activity#GO:0003824;ferric-chelate reductase activity#GO:0000293;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;transition metal ion transport#GO:0000041 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000011844.3|UniProtKB=G3R853 G3R853 LYPD5 PTHR10624:SF9 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR-RELATED LY6_PLAUR DOMAIN-CONTAINING PROTEIN 5 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001477.3|UniProtKB=G3QGK1 G3QGK1 ELSPBP1 PTHR22918:SF2 SEMINAL PLASMA PROTEIN EPIDIDYMAL SPERM-BINDING PROTEIN 1 developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;cellular process#GO:0009987;male gamete generation#GO:0048232;developmental maturation#GO:0021700;sperm capacitation#GO:0048240;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell maturation#GO:0048469 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000016389.3|UniProtKB=A0A2I2YTU1 A0A2I2YTU1 SLC24A1 PTHR10846:SF36 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081 chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;inorganic ion homeostasis#GO:0098771;negative regulation of signaling#GO:0023057;calcium ion homeostasis#GO:0055074;positive regulation of synaptic transmission#GO:0050806;monoatomic ion transport#GO:0006811;negative regulation of cell communication#GO:0010648;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;negative regulation of biological process#GO:0048519;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;regulation of synaptic plasticity#GO:0048167;negative regulation of cellular process#GO:0048523;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;localization#GO:0051179;metal ion transport#GO:0030001;homeostatic process#GO:0042592;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000006777.3|UniProtKB=G3QV79 G3QV79 AP3B2 PTHR11134:SF11 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA-2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 establishment of organelle localization#GO:0051656;cellular component organization#GO:0016043;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;microtubule-based transport#GO:0099111;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;organelle organization#GO:0006996;cellular process#GO:0009987;lysosome organization#GO:0007040;establishment of localization in cell#GO:0051649;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;Golgi vesicle transport#GO:0048193;microtubule-based movement#GO:0007018;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;anterograde axonal transport#GO:0008089;vacuole organization#GO:0007033;organelle localization#GO:0051640;axonal transport#GO:0098930;cytoskeleton-dependent intracellular transport#GO:0030705;axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;anterograde synaptic vesicle transport#GO:0048490;vesicle cytoskeletal trafficking#GO:0099518;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;transport#GO:0006810;vacuolar transport#GO:0007034 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;membrane coat#GO:0030117;coated membrane#GO:0048475 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013493.3|UniProtKB=G3RCE2 G3RCE2 PLXNA3 PTHR22625:SF32 PLEXIN PLEXIN-A3 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;regulation of axonogenesis#GO:0050770;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;positive regulation of axonogenesis#GO:0050772;regulation of multicellular organismal development#GO:2000026;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;signaling#GO:0023052;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;cell projection organization#GO:0030030;developmental process#GO:0032502;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cell adhesion#GO:0007162;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of nervous system development#GO:0051960;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;neuron differentiation#GO:0030182;positive regulation of cell differentiation#GO:0045597;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;synapse assembly#GO:0007416;cell morphogenesis#GO:0000902;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;axon guidance#GO:0007411;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013119.3|UniProtKB=G3RBE9 G3RBE9 BSDC1 PTHR16019:SF5 SYNAPSE-ASSOCIATED PROTEIN BSD DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000043380.1|UniProtKB=A0A2I2ZU63 A0A2I2ZU63 PTHR43948:SF1 DNAJ HOMOLOG SUBFAMILY B DNAJ HOMOLOG SUBFAMILY B MEMBER 3 protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000012605.3|UniProtKB=G3SF52 G3SF52 SLC35E3 PTHR11132:SF250 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E3 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023328.2|UniProtKB=G3SAR3 G3SAR3 ADAM21 PTHR11905:SF116 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 21 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000013343.3|UniProtKB=G3RC00 G3RC00 DLGAP3 PTHR12353:SF4 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 3 modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051 postsynapse#GO:0098794;postsynaptic specialization#GO:0099572;cell junction#GO:0030054;organelle#GO:0043226;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000484.3|UniProtKB=G3QDZ3 G3QDZ3 HSPBP1 PTHR19316:SF18 PROTEIN FOLDING REGULATOR HSP70-BINDING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000007240.3|UniProtKB=G3QWC6 G3QWC6 S100A4 PTHR11639:SF51 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A4 protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000006928.3|UniProtKB=G3QVK2 G3QVK2 KIF2B PTHR24115:SF524 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2B ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000017020.3|UniProtKB=G3RLG4 G3RLG4 MYL11 PTHR23049:SF10 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 11 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022 striated muscle tissue development#GO:0014706;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;muscle organ development#GO:0007517;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;animal organ development#GO:0048513;skeletal muscle tissue development#GO:0007519;tissue development#GO:0009888;muscle structure development#GO:0061061 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000010863.3|UniProtKB=G3S7A7 G3S7A7 KIAA1586 PTHR46880:SF14 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE KIAA1586 ubiquitin-like protein ligase activity#GO:0061659;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein sumoylation#GO:0016925;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687 GORGO|Ensembl=ENSGGOG00000034974.2|UniProtKB=A0A2I2Y6I1 A0A2I2Y6I1 BRD9 PTHR22881:SF4 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN-CONTAINING PROTEIN 9 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000007710.3|UniProtKB=G3RSA8 G3RSA8 BLM PTHR13710:SF163 DNA HELICASE RECQ FAMILY MEMBER RECQ-LIKE DNA HELICASE BLM ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543 telomere organization#GO:0032200;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000002799.3|UniProtKB=G3QJZ6 G3QJZ6 KRT82 PTHR45616:SF12 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CUTICULAR HB2 structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;epidermis development#GO:0008544;developmental process#GO:0032502;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;skin development#GO:0043588;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000004664.3|UniProtKB=G3QPS0 G3QPS0 DBX2 PTHR24331:SF4 DBX HOMEOBOX PROTEIN DBX2 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 GORGO|Ensembl=ENSGGOG00000041863.1|UniProtKB=G3RZG3 G3RZG3 LOC101125692 PTHR24291:SF124 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F2 long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;icosanoid metabolic process#GO:0006690;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;monocarboxylic acid metabolic process#GO:0032787;ketone metabolic process#GO:0042180;carboxylic acid metabolic process#GO:0019752;vitamin K metabolic process#GO:0042373;primary metabolic process#GO:0044238;arachidonate metabolic process#GO:0019369;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010936.3|UniProtKB=A0A2I2ZCM1 A0A2I2ZCM1 PTHR19944:SF98 MHC CLASS II-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488;protein-containing complex binding#GO:0044877 immune system process#GO:0002376;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;regulation of multicellular organismal process#GO:0051239;regulation of T cell activation#GO:0050863;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of immune response#GO:0050776;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;positive regulation of cell adhesion#GO:0045785;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cellular process#GO:0048522;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584 late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000000247.2|UniProtKB=G3QDD0 G3QDD0 MAGEB17 PTHR11736:SF88 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B17 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015543.3|UniProtKB=G3RHN6 G3RHN6 PF4 PTHR12015:SF211 SMALL INDUCIBLE CYTOKINE A PLATELET FACTOR 4 cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 response to other organism#GO:0051707;cell migration#GO:0016477;immune response#GO:0006955;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;cellular response to molecule of bacterial origin#GO:0071219;leukocyte migration#GO:0050900;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;cell chemotaxis#GO:0060326;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;chemotaxis#GO:0006935;inflammatory response#GO:0006954;response to bacterium#GO:0009617;granulocyte migration#GO:0097530;cellular response to lipid#GO:0071396;defense response to other organism#GO:0098542;response to lipid#GO:0033993;neutrophil migration#GO:1990266;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;response to lipopolysaccharide#GO:0032496;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;neutrophil chemotaxis#GO:0030593;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;response to molecule of bacterial origin#GO:0002237;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000036737.1|UniProtKB=A0A2I2YTT2 A0A2I2YTT2 HK1 PTHR19443:SF10 HEXOKINASE HEXOKINASE-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hexokinase activity#GO:0004396 nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;pyruvate metabolic process#GO:0006090;monocarboxylic acid metabolic process#GO:0032787;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;glucose homeostasis#GO:0042593;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;ADP catabolic process#GO:0046032;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;ADP metabolic process#GO:0046031;cellular homeostasis#GO:0019725;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;intracellular glucose homeostasis#GO:0001678;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;chemical homeostasis#GO:0048878;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;glucose 6-phosphate metabolic process#GO:0051156;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;homeostatic process#GO:0042592;nucleoside phosphate metabolic process#GO:0006753;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;energy derivation by oxidation of organic compounds#GO:0015980;intracellular chemical homeostasis#GO:0055082;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic side of membrane#GO:0098562;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Hexokinase#P00677;Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966 GORGO|Ensembl=ENSGGOG00000011768.2|UniProtKB=G3R7X7 G3R7X7 MAB21L1 PTHR10656:SF38 CELL FATE DETERMINING PROTEIN MAB21-RELATED NUCLEOTIDYLTRANSFERASE MAB21L1-RELATED intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transferase#PC00220;nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000003578.3|UniProtKB=A0A2I2Z9T5 A0A2I2Z9T5 CBFA2T2 PTHR10379:SF13 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T2 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000023107.1|UniProtKB=Q9T9Y6 Q9T9Y6 MT-CO3 PTHR11403:SF7 CYTOCHROME C OXIDASE SUBUNIT III CYTOCHROME C OXIDASE SUBUNIT 3 catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324 metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000011325.3|UniProtKB=G3R6S0 G3R6S0 PTK6 PTHR24418:SF265 TYROSINE-PROTEIN KINASE PROTEIN-TYROSINE KINASE 6 binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 developmental process#GO:0032502;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 GORGO|Ensembl=ENSGGOG00000038971.1|UniProtKB=A0A2I2YT20 A0A2I2YT20 PTHR23266:SF341 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008909.3|UniProtKB=G3R0M0 G3R0M0 PRR5L PTHR32428:SF3 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED PROLINE-RICH PROTEIN 5-LIKE protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 positive regulation of response to stimulus#GO:0048584;TOR signaling#GO:0031929;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;TORC2 signaling#GO:0038203;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000027714.2|UniProtKB=G3S975 G3S975 LOC109023026 PTHR11875:SF115 TESTIS-SPECIFIC Y-ENCODED PROTEIN SET protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000040189.1|UniProtKB=A0A2I2YYK7 A0A2I2YYK7 LOC101135632 PTHR24068:SF211 UBIQUITIN-CONJUGATING ENZYME E2 AKT-INTERACTING PROTEIN catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000011023.3|UniProtKB=G3R612 G3R612 ZBTB11 PTHR24409:SF308 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 11 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015174.3|UniProtKB=A0A2I2YLW9 A0A2I2YLW9 AMMECR1 PTHR13016:SF2 AMMECR1 HOMOLOG NUCLEAR PROTEIN AMMECR1 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000026037.2|UniProtKB=G3S147 G3S147 TRAF3IP2 PTHR34257:SF2 ADAPTER PROTEIN CIKS E3 UBIQUITIN LIGASE TRAF3IP2 positive regulation of signaling#GO:0023056;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;humoral immune response#GO:0006959;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000042611.1|UniProtKB=A0A2I2Y5E4 A0A2I2Y5E4 ADIPOQ PTHR15427:SF20 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER ADIPONECTIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>Adiponectin#P06761 GORGO|Ensembl=ENSGGOG00000022844.2|UniProtKB=G3RY41 G3RY41 CD55 PTHR45656:SF15 PROTEIN CBR-CLEC-78 SUSHI DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000027053.2|UniProtKB=A0A2I2Z0V8 A0A2I2Z0V8 PTHR17070:SF1 DEXAMETHASONE-INDUCED PROTEIN SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000009277.2|UniProtKB=G3R1I8 G3R1I8 PTHR22902:SF17 SESQUIPEDALIAN SESQUIPEDALIAN-1 vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;vesicle organization#GO:0016050;endosome organization#GO:0007032;endosomal transport#GO:0016197;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000007744.3|UniProtKB=G3QXN6 G3QXN6 WDHD1 PTHR19932:SF10 WD REPEAT AND HMG-BOX DNA BINDING PROTEIN WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716 replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000011820.3|UniProtKB=G3RU29 G3RU29 TMEM102 PTHR10656:SF48 CELL FATE DETERMINING PROTEIN MAB21-RELATED TRANSMEMBRANE PROTEIN 102 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transferase#PC00220;nucleotidyltransferase#PC00174 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000012050.3|UniProtKB=G3RRY2 G3RRY2 DTX4 PTHR12622:SF5 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX4 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003898.3|UniProtKB=A0A2I2YDT4 A0A2I2YDT4 PTHR35976:SF1 IQ DOMAIN-CONTAINING PROTEIN J IQ DOMAIN-CONTAINING PROTEIN J GORGO|Ensembl=ENSGGOG00000016754.3|UniProtKB=G3RKR1 G3RKR1 LOC101144420 PTHR16788:SF4 EPIDIDYMAL SECRETORY PROTEIN E3 ALPHA EPIDIDYMAL SECRETORY PROTEIN E3-ALPHA GORGO|Ensembl=ENSGGOG00000015408.3|UniProtKB=G3RHB4 G3RHB4 SBSPON PTHR20920:SF2 RPE-SPONDIN SOMATOMEDIN-B AND THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000042706.1|UniProtKB=A0A2I2Z3S6 A0A2I2Z3S6 GPR157 PTHR23112:SF47 G PROTEIN-COUPLED RECEPTOR 157-RELATED G PROTEIN-COUPLED RECEPTOR 157 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016106.3|UniProtKB=G3RJ39 G3RJ39 VWC2L PTHR46252:SF2 BRORIN FAMILY MEMBER VON WILLEBRAND FACTOR C DOMAIN-CONTAINING PROTEIN 2-LIKE regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514;regulation of BMP signaling pathway#GO:0030510;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235;extracellular region#GO:0005576;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 GORGO|Ensembl=ENSGGOG00000023870.2|UniProtKB=G3RPF2 G3RPF2 GOLGA2 PTHR10881:SF58 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 2 mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;Golgi organization#GO:0007030;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;microtubule cytoskeleton organization involved in mitosis#GO:1902850 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi stack#GO:0005795;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;Golgi cis cisterna#GO:0000137;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000041952.1|UniProtKB=A0A2I2YNH3 A0A2I2YNH3 PRND PTHR15506:SF0 DOPPEL PRION PRION-LIKE PROTEIN DOPPEL transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;copper ion binding#GO:0005507;cation binding#GO:0043169;metal ion binding#GO:0046872 reproductive process#GO:0022414;fertilization#GO:0009566;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;single fertilization#GO:0007338;sexual reproduction#GO:0019953;response to metal ion#GO:0010038;cellular response to chemical stimulus#GO:0070887 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 GORGO|Ensembl=ENSGGOG00000037785.1|UniProtKB=G3SGJ4 G3SGJ4 LOC101125671 PTHR23299:SF24 METALLOTHIONEIN METALLOTHIONEIN-1E-RELATED defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014642.3|UniProtKB=G3RFB8 G3RFB8 CASQ1 PTHR10033:SF14 CALSEQUESTRIN CALSEQUESTRIN-1 calcium ion binding#GO:0005509;ion binding#GO:0043167;molecular sequestering activity#GO:0140313;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;signaling#GO:0023052;regulation of transmembrane transport#GO:0034762;regulation of muscle system process#GO:0090257;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of muscle contraction#GO:0006937;regulation of monoatomic ion transport#GO:0043269;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;myofibril#GO:0030016;supramolecular fiber#GO:0099512;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;contractile muscle fiber#GO:0043292;sarcoplasmic reticulum#GO:0016529;Z disc#GO:0030018;sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674;endoplasmic reticulum#GO:0005783 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000012954.3|UniProtKB=G3RR78 G3RR78 NPPB PTHR14066:SF10 ATRIAL NATRIURETIC FACTOR PRECURSOR NATRIURETIC PEPTIDES B signaling receptor binding#GO:0005102;binding#GO:0005488;hormone receptor binding#GO:0051427;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;regulation of systemic arterial blood pressure#GO:0003073;ribose phosphate biosynthetic process#GO:0046390;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;circulatory system process#GO:0003013;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;cell communication#GO:0007154;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;regulation of blood pressure#GO:0008217;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;cyclic nucleotide metabolic process#GO:0009187;system process#GO:0003008;nucleoside phosphate biosynthetic process#GO:1901293 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000004182.3|UniProtKB=G3S027 G3S027 MED15 PTHR31804:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000003453.3|UniProtKB=G3QLN2 G3QLN2 CRIPTO PTHR14949:SF26 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 PROTEIN CRIPTO binding#GO:0005488;signaling receptor binding#GO:0005102;receptor serine/threonine kinase binding#GO:0033612;protein binding#GO:0005515 tube development#GO:0035295;biological regulation#GO:0065007;regionalization#GO:0003002;multicellular organismal process#GO:0032501;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;specification of symmetry#GO:0009799;regulation of cellular process#GO:0050794;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;determination of left/right symmetry#GO:0007368;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;pattern specification process#GO:0007389;determination of bilateral symmetry#GO:0009855;heart development#GO:0007507;vasculogenesis#GO:0001570;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;vasculature development#GO:0001944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;left/right pattern formation#GO:0060972;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;activin receptor signaling pathway#GO:0032924;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000010463.3|UniProtKB=G3R4L2 G3R4L2 PTHR10075:SF132 BASIGIN RELATED IMMUNOGLOBULIN SUPERFAMILY DCC SUBCLASS MEMBER 4 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000014878.3|UniProtKB=A0A2I2ZX98 A0A2I2ZX98 PTHR16943:SF11 2-METHYLCITRATE DEHYDRATASE-RELATED CIS-ACONITATE DECARBOXYLASE carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;regulation of innate immune response#GO:0045088;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;lipid metabolic process#GO:0006629;regulation of response to stress#GO:0080134;fatty acid metabolic process#GO:0006631;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to biotic stimulus#GO:0002831;negative regulation of inflammatory response#GO:0050728;regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;primary metabolic process#GO:0044238;positive regulation of response to external stimulus#GO:0032103;metabolic process#GO:0008152;negative regulation of response to external stimulus#GO:0032102;negative regulation of innate immune response#GO:0045824;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;oxoacid metabolic process#GO:0043436;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;regulation of biological process#GO:0050789;monocarboxylic acid metabolic process#GO:0032787;negative regulation of biological process#GO:0048519;carboxylic acid metabolic process#GO:0019752 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;dehydratase#PC00091;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000010468.3|UniProtKB=G3R4K3 G3R4K3 ZNF263 PTHR23226:SF401 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 263 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001358.3|UniProtKB=G3QG87 G3QG87 LOC101140152 PTHR11387:SF12 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B2 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000012853.3|UniProtKB=G3RAS0 G3RAS0 ERN2 PTHR13954:SF15 IRE1-RELATED SERINE_THREONINE-PROTEIN KINASE_ENDORIBONUCLEASE IRE2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;nuclease activity#GO:0004518;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of cellular process#GO:0050794;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;programmed cell death#GO:0012501;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;apoptotic signaling pathway#GO:0097190 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796 transmembrane signal receptor#PC00197;tyrosine protein kinase receptor#PC00233 Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144;Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110 GORGO|Ensembl=ENSGGOG00000026479.2|UniProtKB=A0A2I2ZXT4 A0A2I2ZXT4 CCN2 PTHR11348:SF7 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 2 integrin binding#GO:0005178;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000034897.2|UniProtKB=G3SKV6 G3SKV6 NSUN7 PTHR14663:SF2 METHYLTRANSFERASE NSUN7-RELATED PROTEIN NSUN7 GORGO|Ensembl=ENSGGOG00000017188.3|UniProtKB=G3RLW2 G3RLW2 CTPS1 PTHR11550:SF8 CTP SYNTHASE CTP SYNTHASE 1 ligase activity#GO:0016874;binding#GO:0005488;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;identical protein binding#GO:0042802;protein binding#GO:0005515 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside triphosphate biosynthetic process#GO:0009142;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753 supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;supramolecular fiber#GO:0099512 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931 GORGO|Ensembl=ENSGGOG00000041425.1|UniProtKB=A0A2I2Z7H9 A0A2I2Z7H9 LOC101136556 PTHR26452:SF695 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Gene=FMO2|UniProtKB=Q8HZ69 Q8HZ69 FMO2 PTHR23023:SF84 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000006573.3|UniProtKB=G3QUM6 G3QUM6 ZNF593 PTHR46095:SF1 ZINC FINGER PROTEIN 593 ZINC FINGER PROTEIN 593 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000003976.3|UniProtKB=G3QMZ9 G3QMZ9 HPX PTHR10201:SF136 MATRIX METALLOPROTEINASE HEMOPEXIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 catabolic process#GO:0009056;heme metabolic process#GO:0042168;cellular component organization#GO:0016043;pigment metabolic process#GO:0042440;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000022800.2|UniProtKB=A0A2I2ZUM3 A0A2I2ZUM3 PTHR14614:SF120 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN VALOSIN CONTAINING PROTEIN LYSINE METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000040397.1|UniProtKB=A0A2I2Z1W1 A0A2I2Z1W1 LOC101126101 PTHR12982:SF2 PHOSPHATIDYLINOSITOL GLYCAN, CLASS C PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000036179.1|UniProtKB=A0A2I2ZKB9 A0A2I2ZKB9 PTHR23266:SF241 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-30-RELATED antigen binding#GO:0003823;binding#GO:0005488 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000009941.3|UniProtKB=A0A2I2YZJ0 A0A2I2YZJ0 RBM7 PTHR13798:SF4 RNA BINDING MOTIF RBM PROTEIN -RELATED RNA-BINDING PROTEIN 7 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012420.3|UniProtKB=G3R9N0 G3R9N0 RNF146 PTHR13417:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF146 E3 UBIQUITIN-PROTEIN LIGASE RNF146 catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate derivative binding#GO:0097367;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002114.3|UniProtKB=A0A2I2YX46 A0A2I2YX46 SFMBT2 PTHR12247:SF62 POLYCOMB GROUP PROTEIN SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 2 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000036905.1|UniProtKB=A0A2I2ZV80 A0A2I2ZV80 TLCD5 PTHR31898:SF1 TRANSMEMBRANE PROTEIN 136 TLC DOMAIN-CONTAINING PROTEIN 5 GORGO|Ensembl=ENSGGOG00000006044.3|UniProtKB=G3QTA2 G3QTA2 HTRA4 PTHR22939:SF105 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA4 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cell death#GO:0008219;protein metabolic process#GO:0019538;proteolysis#GO:0006508;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;positive regulation of apoptotic process#GO:0043065;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000004193.2|UniProtKB=G3QNJ4 G3QNJ4 S1PR2 PTHR22750:SF17 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 2 bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007293.3|UniProtKB=G3QWI1 G3QWI1 PIGA PTHR45871:SF3 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000016366.3|UniProtKB=G3RYJ8 G3RYJ8 TRIM10 PTHR24103:SF696 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 10 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000015535.3|UniProtKB=G3RHM9 G3RHM9 PDGFB PTHR11633:SF2 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR SUBUNIT B protein binding#GO:0005515;growth factor receptor binding#GO:0070851;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of ERK1 and ERK2 cascade#GO:0070372;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;positive regulation of MAPK cascade#GO:0043410;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224;PDGF signaling pathway#P00047>PDGF#P01170 GORGO|Ensembl=ENSGGOG00000014694.3|UniProtKB=G3SHN5 G3SHN5 AHCY PTHR23420:SF34 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000009865.3|UniProtKB=A0A2I2YM34 A0A2I2YM34 ITPRID1 PTHR17469:SF14 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN ITPRID1 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000026891.2|UniProtKB=G3RYD2 G3RYD2 SKIL PTHR10005:SF3 SKI ONCOGENE-RELATED SKI-LIKE PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of biosynthetic process#GO:0009890;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;regulation of primary metabolic process#GO:0080090;regulation of BMP signaling pathway#GO:0030510;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;negative regulation of BMP signaling pathway#GO:0030514;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Gonadotropin-releasing hormone receptor pathway#P06664>SKIL#P06858 GORGO|Ensembl=ENSGGOG00000005890.3|UniProtKB=A0A2I2Z801 A0A2I2Z801 C1QTNF7 PTHR15427:SF24 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 7 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027615.2|UniProtKB=A0A2I2ZED1 A0A2I2ZED1 ERGIC3 PTHR10984:SF85 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000024397.2|UniProtKB=G3RT13 G3RT13 ZBTB14 PTHR24381:SF284 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN CONTAINING 14 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000007586.3|UniProtKB=G3QX83 G3QX83 TSSC4 PTHR13445:SF3 TUMOR SUPPRESSING SUBTRANSFERABLE CANDIDATE 4 TSSC4 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN TSSC4 RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 GORGO|Ensembl=ENSGGOG00000041511.1|UniProtKB=G3S2P7 G3S2P7 LOC109026676 PTHR10715:SF7 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013535.3|UniProtKB=G3RCH8 G3RCH8 PPFIBP2 PTHR12587:SF18 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-BETA-2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;neuromuscular junction development#GO:0007528;cellular component organization#GO:0016043;synapse organization#GO:0050808;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;presynaptic active zone#GO:0048786;synapse#GO:0045202;cell junction#GO:0030054;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000038457.1|UniProtKB=A0A2I2Z3D7 A0A2I2Z3D7 FAM20C PTHR12450:SF11 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 EXTRACELLULAR SERINE_THREONINE PROTEIN KINASE FAM20C protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 developmental process#GO:0032502;biomineral tissue development#GO:0031214;enamel mineralization#GO:0070166;animal gross anatomical part developmental process#GO:0160108;anatomical structure formation involved in morphogenesis#GO:0048646;anatomical structure development#GO:0048856;animal organ development#GO:0048513;amelogenesis#GO:0097186;anatomical structure morphogenesis#GO:0009653;odontogenesis#GO:0042476;animal organ morphogenesis#GO:0009887;tissue development#GO:0009888;odontogenesis of dentin-containing tooth#GO:0042475 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000006739.3|UniProtKB=G3QV31 G3QV31 DDX24 PTHR24031:SF91 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX24 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000014193.3|UniProtKB=A0A2I2Z5V9 A0A2I2Z5V9 INCENP PTHR13142:SF1 INNER CENTROMERE PROTEIN INNER CENTROMERE PROTEIN intracellular organelle#GO:0043229;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;midbody#GO:0030496;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;membraneless organelle#GO:0043228;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000034937.2|UniProtKB=G3SKQ4 G3SKQ4 DHX36 PTHR18934:SF274 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT DNA_RNA HELICASE DHX36 nucleic acid binding#GO:0003676;DNA binding#GO:0003677;RNA binding#GO:0003723;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;DNA helicase activity#GO:0003678 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003016.3|UniProtKB=G3QKI7 G3QKI7 CD300A PTHR11860:SF121 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 8 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015533.3|UniProtKB=G3RHM8 G3RHM8 RAB22A PTHR24073:SF910 DRAB5-RELATED RAS-RELATED PROTEIN RAB-22A ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;late endosome#GO:0005770;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000013859.3|UniProtKB=G3RDC2 G3RDC2 ALOX5AP PTHR10250:SF2 MICROSOMAL GLUTATHIONE S-TRANSFERASE ARACHIDONATE 5-LIPOXYGENASE-ACTIVATING PROTEIN carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;glutathione transferase activity#GO:0004364;oxidoreductase activity#GO:0016491;transferase activity#GO:0016740;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 GORGO|Ensembl=ENSGGOG00000009587.3|UniProtKB=G3R2B4 G3R2B4 GMNN PTHR13372:SF4 GEMININ GEMININ transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA replication#GO:0006275;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of DNA-templated DNA replication initiation#GO:0030174;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cell cycle#GO:0045786 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000008592.3|UniProtKB=G3QZT1 G3QZT1 CHGB PTHR10583:SF4 CHROMOGRANIN SECRETOGRANIN-1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000002549.3|UniProtKB=G3QJB8 G3QJB8 CD69 PTHR45710:SF35 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 EARLY ACTIVATION ANTIGEN CD69 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell activation#GO:0001775;regulation of immune response#GO:0050776;immune system process#GO:0002376;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;T cell activation#GO:0042110;leukocyte activation#GO:0045321;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015559.3|UniProtKB=A0A2I2Z7P9 A0A2I2Z7P9 TP73 PTHR11447:SF21 CELLULAR TUMOR ANTIGEN P53 TUMOR PROTEIN P73 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;programmed cell death#GO:0012501;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of apoptotic process#GO:0042981;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;intrinsic apoptotic signaling pathway#GO:0097193;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 P53-like transcription factor#PC00253;gene-specific transcriptional regulator#PC00264 P53 pathway feedback loops 1#P04392>p73#G04686;p53 pathway by glucose deprivation#P04397>p53#P04640;p53 pathway feedback loops 2#P04398>p53#P04668;P53 pathway feedback loops 1#P04392>p53#P04539;Huntington disease#P00029>p53#P00797;p53 pathway#P00059>p53#P01485;p53 pathway#P00059>p53#G04702 GORGO|Ensembl=ENSGGOG00000002788.3|UniProtKB=G3QJY5 G3QJY5 VEGFD PTHR12025:SF11 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR D signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;molecular function activator activity#GO:0140677;protein binding#GO:0005515;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of leukocyte migration#GO:0002685;response to growth factor#GO:0070848;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of chemotaxis#GO:0050921;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of locomotion#GO:0040017;response to hypoxia#GO:0001666;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of chemotaxis#GO:0050920;vascular endothelial growth factor receptor signaling pathway#GO:0048010;positive regulation of cell motility#GO:2000147;response to endogenous stimulus#GO:0009719;response to abiotic stimulus#GO:0009628;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;regulation of response to external stimulus#GO:0032101;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;multicellular organism development#GO:0007275;positive regulation of response to external stimulus#GO:0032103;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000013137.3|UniProtKB=G3RBG0 G3RBG0 RHPN2 PTHR23031:SF5 RHOPHILIN RHOPHILIN-2-RELATED negative regulation of cytoskeleton organization#GO:0051494;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of biological process#GO:0048519;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002566.3|UniProtKB=G3QJD5 G3QJD5 LRMDA PTHR46282:SF4 LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN cell differentiation#GO:0030154;cellular developmental process#GO:0048869;pigmentation#GO:0043473;developmental process#GO:0032502;developmental pigmentation#GO:0048066;melanocyte differentiation#GO:0030318;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000043796.1|UniProtKB=A0A2I2YME3 A0A2I2YME3 PTHR12840:SF3 NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT COMPLEX I-ASHI respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007751.3|UniProtKB=G3QXN0 G3QXN0 MRPS9 PTHR21569:SF47 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9M binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005033.3|UniProtKB=G3QQQ6 G3QQQ6 EFNB3 PTHR11304:SF34 EPHRIN EPHRIN-B3 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000012583.3|UniProtKB=G3RA29 G3RA29 NUP107 PTHR13003:SF2 NUP107-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP107 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular component organization#GO:0016043;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;protein transport#GO:0015031;protein import into nucleus#GO:0006606;gene expression#GO:0010467;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;RNA localization#GO:0006403;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear pore outer ring#GO:0031080;nucleus#GO:0005634;organelle envelope#GO:0031967 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000037366.1|UniProtKB=A0A2I2YH37 A0A2I2YH37 PTHR22902:SF15 SESQUIPEDALIAN SESQUIPEDALIAN-2 cytosolic transport#GO:0016482;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;endosomal transport#GO:0016197;endosome organization#GO:0007032;vesicle organization#GO:0016050;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;endosome#GO:0005768;organelle subcompartment#GO:0031984;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011319.3|UniProtKB=G3R6R7 G3R6R7 EEF1A2 PTHR23115:SF228 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 2 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000037649.1|UniProtKB=A0A2I2Y5B4 A0A2I2Y5B4 PTHR19433:SF103 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 10 response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000001130.3|UniProtKB=G3QFN7 G3QFN7 DAPP1 PTHR14336:SF15 TANDEM PH DOMAIN CONTAINING PROTEIN DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE ion binding#GO:0043167;phospholipid binding#GO:0005543;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000001276.3|UniProtKB=A0A2I2Z7V8 A0A2I2Z7V8 COL11A1 PTHR24023:SF42 COLLAGEN ALPHA COLLAGEN ALPHA-1(XI) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000039506.1|UniProtKB=A0A2I2Y3R9 A0A2I2Y3R9 PTHR11767:SF21 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267 import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000002646.3|UniProtKB=G3QJK8 G3QJK8 TRAPPC4 PTHR23249:SF15 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 TRAPP complex#GO:0030008;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;protein-containing complex#GO:0032991 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005861.3|UniProtKB=G3QSU4 G3QSU4 VDAC2 PTHR11743:SF12 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL NON-SELECTIVE VOLTAGE-GATED ION CHANNEL VDAC2 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic anion channel activity#GO:0008308;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 mitochondrial transport#GO:0006839;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;intracellular transport#GO:0046907;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000010193.3|UniProtKB=G3R3W6 G3R3W6 PNKP PTHR12083:SF9 BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;nucleobase-containing compound kinase activity#GO:0019205 cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 nucleotide phosphatase#PC00173;phosphatase#PC00181;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000016382.3|UniProtKB=G3RJT6 G3RJT6 DKKL1 PTHR12113:SF7 DICKKOPF3-LIKE 3 DICKKOPF-LIKE PROTEIN 1 signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;signaling receptor regulator activity#GO:0030545 negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of canonical Wnt signaling pathway#GO:0060828 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011430.3|UniProtKB=G3S6E1 G3S6E1 E2F8 PTHR12081:SF40 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000014470.3|UniProtKB=G3REW3 G3REW3 RCE1 PTHR13046:SF0 PROTEASE U48 CAAX PRENYL PROTEASE RCE1 CAAX PRENYL PROTEASE 2 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000007369.3|UniProtKB=A0A2I2YFV1 A0A2I2YFV1 RPRD1A PTHR12460:SF2 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 1A binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000025195.2|UniProtKB=G3RZ04 G3RZ04 TMEM216 PTHR13531:SF5 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 216 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 ciliary transition zone#GO:0035869;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000016416.3|UniProtKB=G3RJW8 G3RJW8 NCOA4 PTHR17085:SF5 NUCLEAR RECEPTOR COACTIVATOR 4 NUCLEAR RECEPTOR COACTIVATOR 4 response to stimulus#GO:0050896;response to chemical#GO:0042221;response to hormone#GO:0009725;response to endogenous stimulus#GO:0009719 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000015741.3|UniProtKB=A0A2I2Y8X9 A0A2I2Y8X9 TRPC7 PTHR10117:SF9 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 7 passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;binding#GO:0005488;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;sexual reproduction#GO:0019953;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;homeostatic process#GO:0042592;reproductive process#GO:0022414;fertilization#GO:0009566;regulation of cytosolic calcium ion concentration#GO:0051480;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;single fertilization#GO:0007338 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 GORGO|Ensembl=ENSGGOG00000038059.1|UniProtKB=A0A2I2ZGH9 A0A2I2ZGH9 PTHR45633:SF17 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;T cell activation#GO:0042110;regulation of lymphocyte activation#GO:0051249;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;response to unfolded protein#GO:0006986;positive regulation of cell-cell adhesion#GO:0022409;response to stress#GO:0006950;mitochondrion organization#GO:0007005;regulation of multicellular organismal process#GO:0051239;apoptotic mitochondrial changes#GO:0008637;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;positive regulation of leukocyte activation#GO:0002696;metabolic process#GO:0008152;cell death#GO:0008219;positive regulation of cell adhesion#GO:0045785;leukocyte activation#GO:0045321;positive regulation of cytokine production#GO:0001819;cell activation#GO:0001775;cellular response to unfolded protein#GO:0034620;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;regulation of macromolecule biosynthetic process#GO:0010556;mitochondrial protein import pathway#GO:7770058;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;positive regulation of multicellular organismal process#GO:0051240;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;immune system process#GO:0002376;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular localization#GO:0051641;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;positive regulation of immune system process#GO:0002684;positive regulation of macromolecule metabolic process#GO:0010604;lymphocyte activation#GO:0046649;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;positive regulation of type I interferon production#GO:0032481;programmed cell death#GO:0012501;regulation of macromolecule metabolic process#GO:0060255;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to topologically incorrect protein#GO:0035967;positive regulation of lymphocyte activation#GO:0051251;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biosynthetic process#GO:0009058;positive regulation of cell activation#GO:0050867;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;transport#GO:0006810;intracellular transport#GO:0046907;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle membrane#GO:0031090;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866 GORGO|Ensembl=ENSGGOG00000012676.3|UniProtKB=G3RAB1 G3RAB1 ZFYVE9 PTHR46319:SF2 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 9 biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;vesicle-mediated transport#GO:0016192;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;intracellular transport#GO:0046907;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;localization#GO:0051179;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular localization#GO:0051641;response to transforming growth factor beta#GO:0071559 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506 TGF-beta signaling pathway#P00052>SARA#P01281 GORGO|Ensembl=ENSGGOG00000015350.3|UniProtKB=G3RH82 G3RH82 COL5A3 PTHR24023:SF1023 COLLAGEN ALPHA COLLAGEN ALPHA-3(V) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000010203.3|UniProtKB=G3R3W9 G3R3W9 GPR27 PTHR19268:SF8 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 27-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016643.3|UniProtKB=G3RKH3 G3RKH3 SKA1 PTHR28573:SF1 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 SKA COMPLEX SUBUNIT 1 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 regulation of microtubule-based process#GO:0032886;chromosome segregation#GO:0007059;regulation of microtubule polymerization or depolymerization#GO:0031110;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007 outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;chromosome#GO:0005694;kinetochore#GO:0000776 GORGO|Ensembl=ENSGGOG00000013029.3|UniProtKB=G3RB72 G3RB72 SLC33A1 PTHR12778:SF9 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED ACETYL-COENZYME A TRANSPORTER 1 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000006864.3|UniProtKB=G3QVF5 G3QVF5 LOC101127903 PTHR45629:SF15 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000012306.3|UniProtKB=G3RQH0 G3RQH0 NMNAT3 PTHR12039:SF7 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 nucleotidyltransferase#PC00174;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000005875.3|UniProtKB=A0A2I2Y7Y2 A0A2I2Y7Y2 RFC4 PTHR11669:SF20 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 4 ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 GORGO|Ensembl=ENSGGOG00000005181.3|UniProtKB=A0A2I2Z5B1 A0A2I2Z5B1 PKNOX2 PTHR11850:SF53 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN PKNOX2 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000022193.2|UniProtKB=G3SFD2 G3SFD2 ECSCR PTHR28602:SF1 ENDOTHELIAL CELL-SPECIFIC CHEMOTAXIS REGULATOR ENDOTHELIAL CELL-SPECIFIC CHEMOTAXIS REGULATOR positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of protein catabolic process#GO:0042176;regulation of angiogenesis#GO:0045765;positive regulation of protein catabolic process#GO:0045732;negative regulation of multicellular organismal process#GO:0051241;regulation of programmed cell death#GO:0043067;positive regulation of proteasomal protein catabolic process#GO:1901800;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of vasculature development#GO:1901342;regulation of apoptotic process#GO:0042981;negative regulation of angiogenesis#GO:0016525;positive regulation of catabolic process#GO:0009896;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of apoptotic process#GO:0043065;regulation of catabolic process#GO:0009894;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000013901.3|UniProtKB=G3RDF2 G3RDF2 PSMB10 PTHR11599:SF41 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-10 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000011540.3|UniProtKB=G3R7C0 G3R7C0 SLC22A31 PTHR24064:SF196 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 31-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000009038.3|UniProtKB=G3RY04 G3RY04 SLC35D1 PTHR11132:SF247 SOLUTE CARRIER FAMILY 35 NUCLEOTIDE SUGAR TRANSPORTER SLC35D1 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;nucleotide-sugar transmembrane transport#GO:0015780;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011756.3|UniProtKB=G3R7X0 G3R7X0 CLCA1 PTHR10579:SF52 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1 gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;chloride channel activity#GO:0005254;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000008386.3|UniProtKB=G3QZ91 G3QZ91 LACRT PTHR40711:SF2 DERMCIDIN-RELATED EXTRACELLULAR GLYCOPROTEIN LACRITIN signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological regulation#GO:0065007;response to other organism#GO:0051707;intracellular signaling cassette#GO:0141124;response to external stimulus#GO:0009605;defense response#GO:0006952;calcium-mediated signaling#GO:0019722;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000023557.2|UniProtKB=G3RRG3 G3RRG3 LOC101134056 PTHR26453:SF102 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2L13 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014266.3|UniProtKB=G3RED4 G3RED4 HMGXB4 PTHR46584:SF1 HMG DOMAIN-CONTAINING PROTEIN 4 HMG DOMAIN-CONTAINING PROTEIN 4 HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000000133.3|UniProtKB=G3S5B3 G3S5B3 LOC101141065 PTHR24291:SF63 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4X1-RELATED oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000028181.2|UniProtKB=G3RQH3 G3RQH3 SCLT1 PTHR35970:SF1 SODIUM CHANNEL AND CLATHRIN LINKER 1 SODIUM CHANNEL AND CLATHRIN LINKER 1 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001396.3|UniProtKB=G3QGC3 G3QGC3 CCNP PTHR10177:SF257 CYCLINS CYCLIN-P cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000011943.3|UniProtKB=Q0MQI5 Q0MQI5 NDUFV1 PTHR11780:SF10 NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1 NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010450.3|UniProtKB=A0A2I2YTP9 A0A2I2YTP9 ARSB PTHR10342:SF276 ARYLSULFATASE ARYLSULFATASE B hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 GORGO|Ensembl=ENSGGOG00000041519.1|UniProtKB=A0A2I2Z5W4 A0A2I2Z5W4 PTHR45995:SF3 FAMILY NOT NAMED PEPTIDYLPROLYL ISOMERASE organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000023672.2|UniProtKB=G3QRN3 G3QRN3 PTHR13718:SF122 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016297.3|UniProtKB=A0A2I2Z9E2 A0A2I2Z9E2 TCF4 PTHR11793:SF10 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 CCKR signaling map#P06959>TCF7L2#P07126 GORGO|Ensembl=ENSGGOG00000034886.2|UniProtKB=G3SKF2 G3SKF2 SORCS3 PTHR12106:SF10 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS3 transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 postsynapse#GO:0098794;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;Golgi apparatus#GO:0005794;cell junction#GO:0030054 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000007284.3|UniProtKB=A0A2I2ZAN7 A0A2I2ZAN7 RNF157 PTHR22996:SF1 MAHOGUNIN E3 UBIQUITIN LIGASE RNF157 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000007904.3|UniProtKB=G3QY13 G3QY13 MAPK15 PTHR24055:SF79 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 15 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 PDGF signaling pathway#P00047>ERK#P01143;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interleukin signaling pathway#P00036>ERK#P00965;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Parkinson disease#P00049>ERK#P01211;EGF receptor signaling pathway#P00018>ERK1-2#P00543 GORGO|Ensembl=ENSGGOG00000010292.3|UniProtKB=G3R452 G3R452 ZNF646 PTHR24409:SF450 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001653.3|UniProtKB=G3QH12 G3QH12 FAM53B PTHR28567:SF1 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53B positive regulation of Wnt signaling pathway#GO:0030177;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;intracellular protein transport#GO:0006886;regulation of Wnt signaling pathway#GO:0030111;regulation of biological process#GO:0050789;protein transport#GO:0015031;protein import into nucleus#GO:0006606;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;positive regulation of canonical Wnt signaling pathway#GO:0090263;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular transport#GO:0046907;regulation of cell communication#GO:0010646;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of signal transduction#GO:0009967;nuclear transport#GO:0051169;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000026108.2|UniProtKB=A0A2I2Z753 A0A2I2Z753 TNFRSF14 PTHR46838:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 positive regulation of cytokine production#GO:0001819;regulation of leukocyte migration#GO:0002685;response to external biotic stimulus#GO:0043207;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of lymphocyte migration#GO:2000401;response to bacterium#GO:0009617;regulation of cell motility#GO:2000145;positive regulation of biosynthetic process#GO:0009891;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cell adhesion#GO:0007162;response to other organism#GO:0051707;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;positive regulation of gene expression#GO:0010628;positive regulation of cell motility#GO:2000147;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of lymphocyte activation#GO:0051249;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;positive regulation of metabolic process#GO:0009893;response to stress#GO:0006950;regulation of T cell activation#GO:0050863;negative regulation of cell-cell adhesion#GO:0022408;regulation of multicellular organismal process#GO:0051239;negative regulation of multicellular organismal process#GO:0051241;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of T cell proliferation#GO:0042129;negative regulation of T cell activation#GO:0050868;regulation of immune effector process#GO:0002697;regulation of cell population proliferation#GO:0042127;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;positive regulation of immune effector process#GO:0002699;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;negative regulation of cell activation#GO:0050866;regulation of biosynthetic process#GO:0009889;defense response#GO:0006952;positive regulation of locomotion#GO:0040017;negative regulation of biological process#GO:0048519;positive regulation of multicellular organismal process#GO:0051240;defense response to Gram-positive bacterium#GO:0050830;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cytokine production involved in immune response#GO:0002718;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008483.3|UniProtKB=G3QZH9 G3QZH9 MFSD14B PTHR23504:SF32 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 71 MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000012677.3|UniProtKB=G3RAA3 G3RAA3 EFCAB14 PTHR15717:SF2 PROTEIN KIAA0494 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 14 GORGO|Ensembl=ENSGGOG00000017047.3|UniProtKB=G3RLI8 G3RLI8 ENAM PTHR16784:SF2 ENAMELIN ENAMELIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 regulation of developmental process#GO:0050793;odontogenesis#GO:0042476;cell differentiation#GO:0030154;animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;odontogenesis of dentin-containing tooth#GO:0042475;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;amelogenesis#GO:0097186;anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;animal organ development#GO:0048513;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000016036.3|UniProtKB=G3RIX8 G3RIX8 GPAT4 PTHR23063:SF37 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000023455.2|UniProtKB=A0A2I2YWE3 A0A2I2YWE3 GMCL2 PTHR23231:SF18 GERM CELL-LESS PROTEIN GERM CELL-LESS PROTEIN-LIKE 2 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000013704.3|UniProtKB=G3RSU7 G3RSU7 KCNK15 PTHR11003:SF18 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 15 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215 transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003176.3|UniProtKB=G3S059 G3S059 POP1 PTHR22731:SF3 RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1 RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;ribonuclease P activity#GO:0004526;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840 sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleolar ribonuclease P complex#GO:0005655;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348;ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000027160.2|UniProtKB=G3SJL1 G3SJL1 TCN1 PTHR10559:SF13 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR TRANSCOBALAMIN-1 binding#GO:0005488;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906 transport#GO:0006810;nitrogen compound transport#GO:0071705;localization#GO:0051179;vitamin transport#GO:0051180;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000002021.3|UniProtKB=G3QI00 G3QI00 PLEKHO1 PTHR15871:SF1 PH DOMAIN-CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY O MEMBER 1 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;ruffle#GO:0001726;cell projection membrane#GO:0031253;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256 GORGO|Ensembl=ENSGGOG00000008614.3|UniProtKB=G3QZV5 G3QZV5 ACSL4 PTHR43272:SF22 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 4 ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;neurogenesis#GO:0022008;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;lipid metabolic process#GO:0006629;neuron differentiation#GO:0030182;developmental process#GO:0032502;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000039926.1|UniProtKB=A0A2I2ZI35 A0A2I2ZI35 ANKRD34C PTHR24156:SF6 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN 34C GORGO|Ensembl=ENSGGOG00000002002.3|UniProtKB=G3QHY3 G3QHY3 ABCG2 PTHR48041:SF92 ABC TRANSPORTER G FAMILY MEMBER 28 BROAD SUBSTRATE SPECIFICITY ATP-BINDING CASSETTE TRANSPORTER ABCG2 efflux transmembrane transporter activity#GO:0015562;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 circulatory system process#GO:0003013;transmembrane transport#GO:0055085;localization#GO:0051179;inorganic anion transport#GO:0015698;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;export from cell#GO:0140352;xenobiotic transport#GO:0042908;transport#GO:0006810;establishment of localization#GO:0051234;system process#GO:0003008;detoxification of inorganic compound#GO:0061687;cellular process#GO:0009987;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;detoxification#GO:0098754 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000028245.2|UniProtKB=G3RSH7 G3RSH7 GPR63 PTHR24245:SF1 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 63-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026157.2|UniProtKB=G3S9H5 G3S9H5 LOC101141950 PTHR26452:SF933 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14I1-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000024935.2|UniProtKB=G3S0F9 G3S0F9 TRAPPC14 PTHR16096:SF8 MICROTUBULE-ASSOCIATED PROTEIN 11 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 14 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cytoplasm#GO:0005737;TRAPP complex#GO:0030008;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000040137.1|UniProtKB=A0A2I2Z716 A0A2I2Z716 PTHR23267:SF176 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 8-61 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014527.3|UniProtKB=G3RF15 G3RF15 UBLCP1 PTHR48493:SF1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000003707.3|UniProtKB=G3RPN0 G3RPN0 FUS PTHR23238:SF5 RNA BINDING PROTEIN RNA-BINDING PROTEIN FUS RNA binding#GO:0003723;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000038050.1|UniProtKB=A0A2I2ZSR1 A0A2I2ZSR1 AMIGO2 PTHR24368:SF209 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 2 anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell adhesion#GO:0007155;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;brain development#GO:0007420;nervous system development#GO:0007399;head development#GO:0060322;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000352.3|UniProtKB=G3QDM3 G3QDM3 CDC42BPG PTHR22988:SF22 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE MRCK GAMMA transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000000917.3|UniProtKB=A0A2I2ZVY6 A0A2I2ZVY6 MRGPRG PTHR11334:SF32 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER G transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007989.3|UniProtKB=G3QY84 G3QY84 TMEFF2 PTHR10913:SF80 FOLLISTATIN-RELATED TOMOREGULIN-2 cellular process#GO:0009987;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell differentiation#GO:0030154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000041139.1|UniProtKB=A0A2I2Y5R5 A0A2I2Y5R5 IGLC7 PTHR23266:SF283 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 2-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000024560.2|UniProtKB=G3S065 G3S065 EIF4EBP1 PTHR12669:SF14 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1 binding#GO:0005488;translation initiation factor binding#GO:0031369;protein binding#GO:0005515;translation regulator activity#GO:0045182 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translation initiation factor#PC00224 p53 pathway by glucose deprivation#P04397>4E-BP1#P04637;p38 MAPK pathway#P05918>4E-BP1#P06042;CCKR signaling map#P06959>4E-BP1#P07230 GORGO|Ensembl=ENSGGOG00000015097.3|UniProtKB=G3RZJ2 G3RZJ2 CCDC9 PTHR15635:SF11 COILED-COIL DOMAIN CONTAINING PROTEIN 9 COILED-COIL DOMAIN-CONTAINING PROTEIN 9 GORGO|Ensembl=ENSGGOG00000007922.3|UniProtKB=G3QY29 G3QY29 THOP1 PTHR11804:SF50 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED THIMET OLIGOPEPTIDASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000039900.1|UniProtKB=A0A2I2ZS15 A0A2I2ZS15 PTHR22747:SF32 NUCLEOPLASMIN NUCLEOPHOSMIN protein binding#GO:0005515;RNA binding#GO:0003723;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of transcription by RNA polymerase II#GO:0045944;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cell cycle process#GO:0010564;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular localization#GO:0051641;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;ribosomal large subunit export from nucleus#GO:0000055;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;establishment of organelle localization#GO:0051656;regulation of cell cycle#GO:0051726;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;organelle localization#GO:0051640;regulation of microtubule-based process#GO:0032886;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;nuclear transport#GO:0051169;nuclear export#GO:0051168;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000013208.3|UniProtKB=G3RBN8 G3RBN8 COL1A1 PTHR24023:SF569 COLLAGEN ALPHA COLLAGEN ALPHA-1(I) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;animal organ morphogenesis#GO:0009887;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;system development#GO:0048731;external encapsulating structure organization#GO:0045229;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;skeletal system development#GO:0001501;cellular process#GO:0009987;skeletal system morphogenesis#GO:0048705;skin development#GO:0043588;multicellular organismal process#GO:0032501;developmental process#GO:0032502;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000001124.3|UniProtKB=G3QFN0 G3QFN0 MTFMT PTHR11138:SF5 METHIONYL-TRNA FORMYLTRANSFERASE METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000000909.3|UniProtKB=G3QF34 G3QF34 SASS6 PTHR44281:SF4 SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;male gamete generation#GO:0048232;cytoskeleton organization#GO:0007010;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;centriole replication#GO:0007099;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;gamete generation#GO:0007276;reproductive process#GO:0022414 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000014241.3|UniProtKB=G3REB7 G3REB7 E4F1 PTHR24408:SF31 ZINC FINGER PROTEIN TRANSCRIPTION FACTOR E4F1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000017167.3|UniProtKB=G3RLU4 G3RLU4 TMEM255B PTHR33721:SF3 TRANSMEMBRANE PROTEIN 255B-LIKE TRANSMEMBRANE PROTEIN 255B GORGO|Ensembl=ENSGGOG00000015065.3|UniProtKB=G3RGF6 G3RGF6 POFUT2 PTHR13398:SF0 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000012639.3|UniProtKB=G3RA72 G3RA72 MCEMP1 PTHR37856:SF1 MAST CELL-EXPRESSED MEMBRANE PROTEIN 1 MAST CELL-EXPRESSED MEMBRANE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000005751.3|UniProtKB=G3RZF3 G3RZF3 ALOXE3 PTHR11771:SF184 LIPOXYGENASE HYDROPEROXIDE ISOMERASE ALOXE3 catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 monocarboxylic acid biosynthetic process#GO:0072330;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;icosanoid metabolic process#GO:0006690;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid oxidation#GO:0034440;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;arachidonate metabolic process#GO:0019369 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000006949.3|UniProtKB=A0A2I2Z2K1 A0A2I2Z2K1 NAV2 PTHR12784:SF6 STEERIN NEURON NAVIGATOR 2 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;nervous system development#GO:0007399;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 GORGO|Ensembl=ENSGGOG00000026378.2|UniProtKB=G3SAY3 G3SAY3 LOC101132158 PTHR11594:SF14 40S RIBOSOMAL PROTEIN S27 40S RIBOSOMAL PROTEIN S27 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;protein biosynthetic process#GO:0160307;translation#GO:0006412;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000024306.2|UniProtKB=G3S382 G3S382 PTHR15710:SF21 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF126 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular response to misfolded protein#GO:0071218;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to stress#GO:0006950;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;cellular response to topologically incorrect protein#GO:0035967;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;response to topologically incorrect protein#GO:0035966 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000001246.3|UniProtKB=G3QFY8 G3QFY8 FGF21 PTHR11486:SF81 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 21 signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104 response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;signaling#GO:0023052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000014589.4|UniProtKB=G3RF78 G3RF78 KIF17 PTHR24115:SF1046 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF17 microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000040634.1|UniProtKB=A0A2I2YLT3 A0A2I2YLT3 PTHR45696:SF9 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 kinase activator activity#GO:0019209;binding#GO:0005488;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000024177.2|UniProtKB=G3SFJ2 G3SFJ2 LOC101154539 PTHR11905:SF167 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN A DISINTEGRIN AND METALLOPEPTIDASE DOMAIN 4-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 multicellular organismal process#GO:0032501;gonad development#GO:0008406;male gonad development#GO:0008584;sex differentiation#GO:0007548;cellular process#GO:0009987;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;animal organ development#GO:0048513;development of primary male sexual characteristics#GO:0046546;metabolic process#GO:0008152;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;male sex differentiation#GO:0046661;reproductive process#GO:0022414;reproductive structure development#GO:0048608;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;reproductive system development#GO:0061458;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000041785.1|UniProtKB=G3S3W8 G3S3W8 LOC109023158 PTHR23266:SF372 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-23-RELATED binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000009787.3|UniProtKB=G3R2U8 G3R2U8 BCL6B PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012174.3|UniProtKB=G3R902 G3R902 NUDT22 PTHR31835:SF1 URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT22 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000015759.3|UniProtKB=G3RI80 G3RI80 CASP5 PTHR10454:SF243 CASPASE CASPASE-5 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;response to stress#GO:0006950;regulation of neuron apoptotic process#GO:0043523;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of defense response#GO:0031349;positive regulation of inflammatory response#GO:0050729;regulation of response to stress#GO:0080134;positive regulation of neuron apoptotic process#GO:0043525;defense response#GO:0006952;positive regulation of response to external stimulus#GO:0032103;positive regulation of apoptotic process#GO:0043065;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;inflammatory response#GO:0006954 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;canonical inflammasome complex#GO:0061702;cytosol#GO:0005829 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000022530.2|UniProtKB=A0A2I2ZSA2 A0A2I2ZSA2 LOC101144649 PTHR10219:SF111 GLYCOLIPID TRANSFER PROTEIN-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8 phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;molecular carrier activity#GO:0140104;ion binding#GO:0043167;lipid carrier activity#GO:0005319;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;transporter activity#GO:0005215 membrane organization#GO:0061024;lipid transport#GO:0006869;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;ceramide transport#GO:0035627;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;lipid localization#GO:0010876 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000004044.3|UniProtKB=G3QN62 G3QN62 PRG3 PTHR10068:SF8 BONE MARROW PROTEOGLYCAN PROTEOGLYCAN 3 extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000011929.3|UniProtKB=G3R8D7 G3R8D7 PRKAR1B PTHR11635:SF126 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I-BETA REGULATORY SUBUNIT kinase inhibitor activity#GO:0019210;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;protein kinase A binding#GO:0051018;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;kinase binding#GO:0019900;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;enzyme inhibitor activity#GO:0004857;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Hedgehog signaling pathway#P00025>PKA#P00682;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Gonadotropin-releasing hormone receptor pathway#P06664>PKA#P06782;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Endothelin signaling pathway#P00019>PKA#P00570;GABA-B receptor II signaling#P05731>PKA#P05752;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050 GORGO|Ensembl=ENSGGOG00000003864.3|UniProtKB=G3QMQ4 G3QMQ4 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 membraneless organelle#GO:0043228;transferase complex#GO:1990234;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;site of double-strand break#GO:0035861;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000016964.3|UniProtKB=G3RLA9 G3RLA9 C1H1orf54 PTHR37870:SF1 CHROMOSOME 1 OPEN READING FRAME 54 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 54 GORGO|Ensembl=ENSGGOG00000037921.1|UniProtKB=A0A2I2YGF4 A0A2I2YGF4 PTHR11909:SF537 CASEIN KINASE-RELATED PROTEIN KINASE DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of canonical Wnt signaling pathway#GO:0060828;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000005683.3|UniProtKB=G3S5R3 G3S5R3 MESP2 PTHR20937:SF17 IP14615P MESODERM POSTERIOR PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;heart morphogenesis#GO:0003007;mesoderm morphogenesis#GO:0048332;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;mesoderm formation#GO:0001707;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regionalization#GO:0003002;formation of primary germ layer#GO:0001704;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;gastrulation#GO:0007369;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;anterior/posterior pattern specification#GO:0009952;anatomical structure formation involved in morphogenesis#GO:0048646;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anterior/posterior axis specification#GO:0009948;mesoderm development#GO:0007498;animal organ development#GO:0048513;embryonic pattern specification#GO:0009880;embryo development#GO:0009790;heart development#GO:0007507 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000012555.3|UniProtKB=G3S6E5 G3S6E5 PPL PTHR23169:SF10 ENVOPLAKIN PERIPLAKIN wound healing#GO:0042060;cellular component organization or biogenesis#GO:0071840;intermediate filament-based process#GO:0045103;cytoskeleton organization#GO:0007010;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;response to wounding#GO:0009611;response to stress#GO:0006950 intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;membrane#GO:0016020 intermediate filament#PC00129;intermediate filament binding protein#PC00130 GORGO|Ensembl=ENSGGOG00000042262.1|UniProtKB=A0A2I2Y741 A0A2I2Y741 LOC109024249 PTHR10768:SF40 60S RIBOSOMAL PROTEIN L37 60S RIBOSOMAL PROTEIN L37 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003174.3|UniProtKB=G3QKY2 G3QKY2 TSPYL6 PTHR11875:SF29 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 6 binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000015641.3|UniProtKB=G3RHY1 G3RHY1 ATP5MC2 PTHR10031:SF56 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, MITOCHONDRIAL ATP synthase#PC00002;transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000015237.3|UniProtKB=G3RGV9 G3RGV9 MIER3 PTHR10865:SF22 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 3 histone deacetylase binding#GO:0042826;protein binding#GO:0005515;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription coregulator activity#GO:0003712;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110 negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000007785.3|UniProtKB=G3QXQ6 G3QXQ6 NUDT19 PTHR12318:SF0 TESTOSTERONE-REGULATED PROTEIN RP2 ACYL-COENZYME A DIPHOSPHATASE NUDT19 GORGO|Ensembl=ENSGGOG00000008789.3|UniProtKB=G3R0B1 G3R0B1 VPS35 PTHR11099:SF0 VACUOLAR SORTING PROTEIN 35 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 establishment of protein localization to membrane#GO:0090150;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;endosome to plasma membrane protein transport#GO:0099638;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;endocytic recycling#GO:0032456;cytosolic transport#GO:0016482;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;retromer complex#GO:0030904;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006379.3|UniProtKB=A0A2I2ZCR8 A0A2I2ZCR8 PTHR13140:SF273 MYOSIN UNCONVENTIONAL MYOSIN-VA microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 actin cytoskeleton#GO:0015629;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000016402.3|UniProtKB=G3RJV5 G3RJV5 AMTN PTHR36858:SF1 AMELOTIN AMELOTIN GORGO|Ensembl=ENSGGOG00000013516.3|UniProtKB=A0A2I2Z5N9 A0A2I2Z5N9 CD300LF PTHR11860:SF119 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune system process#GO:0002376;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000007981.3|UniProtKB=G3S6B3 G3S6B3 TMEM59 PTHR28652:SF3 TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN TRANSMEMBRANE PROTEIN 59 positive regulation of catabolic process#GO:0009896;positive regulation of metabolic process#GO:0009893;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;positive regulation of autophagy#GO:0010508;regulation of autophagy#GO:0010506;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789 intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;late endosome#GO:0005770;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323 GORGO|Ensembl=ENSGGOG00000043924.1|UniProtKB=A0A2I2Y9U9 A0A2I2Y9U9 ZNF630 PTHR23226:SF412 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001901.3|UniProtKB=G3QHN8 G3QHN8 RNF25 PTHR13198:SF4 RING FINGER PROTEIN 25 E3 UBIQUITIN-PROTEIN LIGASE RNF25 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;translational elongation#GO:0006414;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;modification-dependent protein catabolic process#GO:0019941;rescue of stalled cytosolic ribosome#GO:0072344;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cytoplasmic translation#GO:0002181;catabolic process#GO:0009056;protein biosynthetic process#GO:0160307;protein catabolic process#GO:0030163;translation#GO:0006412;modification-dependent macromolecule catabolic process#GO:0043632;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000011839.3|UniProtKB=G3R858 G3R858 QRICH2 PTHR46766:SF2 GLUTAMINE-RICH PROTEIN 2 GLUTAMINE-RICH PROTEIN 2 cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;flagellated sperm motility#GO:0030317;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;sperm motility#GO:0097722;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell projection organization#GO:0030030;reproductive process#GO:0022414;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285 cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000013423.3|UniProtKB=G3RV92 G3RV92 FLAD1 PTHR23293:SF9 FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE BIFUNCTIONAL FAD DIPHOSPHATASE_FAD SYNTHASE transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;flavin-containing compound metabolic process#GO:0042726;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 metabolite interconversion enzyme#PC00262;transferase#PC00220 Flavin biosynthesis#P02741>FAD synthetase#P02936 GORGO|Ensembl=ENSGGOG00000014414.3|UniProtKB=A0A2I2Z0W3 A0A2I2Z0W3 RPS16 PTHR21569:SF41 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000022151.2|UniProtKB=G3RUN1 G3RUN1 LOC101126086 PTHR15633:SF4 NUCLEOLAR PROTEIN 11 NUCLEOLAR PROTEIN 11 nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000010272.3|UniProtKB=G3R435 G3R435 FN3K PTHR12149:SF9 FRUCTOSAMINE 3 KINASE-RELATED PROTEIN FRUCTOSAMINE-3-KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein repair#GO:0030091 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000038149.1|UniProtKB=G3RUG5 G3RUG5 PTHR23266:SF277 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-13 antigen binding#GO:0003823;binding#GO:0005488 immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000043955.1|UniProtKB=A0A2I2Z293 A0A2I2Z293 EIF3F PTHR10540:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F hydrolase activity#GO:0016787;protein binding#GO:0005515;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;binding#GO:0005488;peptidase activity#GO:0008233;translation initiation factor activity#GO:0003743;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;translation initiation factor binding#GO:0031369;translation factor activity#GO:0180051;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000011847.3|UniProtKB=G3R860 G3R860 KIF11 PTHR47970:SF26 KINESIN-LIKE PROTEIN KIF11 KINESIN-LIKE PROTEIN KIF11 ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule motor activity#GO:0003777;plus-end-directed microtubule motor activity#GO:0008574;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 organelle assembly#GO:0070925;nuclear division#GO:0000280;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;chromosome segregation#GO:0007059;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231 intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;spindle microtubule#GO:0005876;microtubule#GO:0005874;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;spindle#GO:0005819;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000005586.3|UniProtKB=G3QS42 G3QS42 CLIC4 PTHR45476:SF5 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL 4-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;monoatomic anion transport#GO:0006820 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000009360.3|UniProtKB=G3R1S0 G3R1S0 DPH1 PTHR10762:SF1 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1 cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 GORGO|Ensembl=ENSGGOG00000014660.3|UniProtKB=A0A2I2YW92 A0A2I2YW92 NEK4 PTHR43671:SF104 SERINE/THREONINE-PROTEIN KINASE NEK SI:CH211-285C6.2-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011748.3|UniProtKB=G3R7V8 G3R7V8 NTMT2 PTHR12753:SF2 AD-003 - RELATED N-TERMINAL XAA-PRO-LYS N-METHYLTRANSFERASE 2 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 methyltransferase#PC00155;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000010049.3|UniProtKB=G3R3I2 G3R3I2 TEX264 PTHR15949:SF3 TESTIS-EXPRESSED PROTEIN 264 TESTIS-EXPRESSED PROTEIN 264 nucleobase-containing compound metabolic process#GO:0006139;macroautophagy#GO:0016236;reticulophagy#GO:0061709;response to stress#GO:0006950;autophagy#GO:0006914;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;response to stimulus#GO:0050896;catabolic process#GO:0009056;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554 chromosome#GO:0005694;replication fork#GO:0005657;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;autophagosome#GO:0005776;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;nucleus#GO:0005634;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular membraneless organelle#GO:0043232;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 GORGO|Ensembl=ENSGGOG00000003568.3|UniProtKB=G3QLY1 G3QLY1 PTHR24412:SF420 KELCH PROTEIN KELCH-LIKE PROTEIN 11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006610.3|UniProtKB=G3QUQ9 G3QUQ9 BNC1 PTHR15021:SF1 DISCONNECTED-RELATED ZINC FINGER PROTEIN BASONUCLIN-1 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase I#GO:0006356 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000016873.3|UniProtKB=G3RL32 G3RL32 KRT36 PTHR23239:SF204 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA6 structural molecule activity#GO:0005198 intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;developmental process#GO:0032502;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000009537.3|UniProtKB=G3R279 G3R279 NRP2 PTHR46806:SF2 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN NEUROPILIN-2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182 plasma membrane region#GO:0098590;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic membrane#GO:0045211;axon#GO:0030424;synaptic membrane#GO:0097060 GORGO|Ensembl=ENSGGOG00000016829.3|UniProtKB=G3S699 G3S699 AGPAT2 PTHR10434:SF2 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE BETA acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000010341.3|UniProtKB=G3SDK8 G3SDK8 BPTF PTHR45975:SF2 NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF GORGO|Ensembl=ENSGGOG00000026073.2|UniProtKB=G3RQ15 G3RQ15 WDR12 PTHR19855:SF40 WD40 REPEAT PROTEIN 12, 37 RIBOSOME BIOGENESIS PROTEIN WDR12 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000043175.1|UniProtKB=A0A2I2ZPC6 A0A2I2ZPC6 CBFB PTHR10276:SF3 CORE-BINDING FACTOR, BETA SUBUNIT CORE-BINDING FACTOR SUBUNIT BETA transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;transcription coactivator activity#GO:0003713;DNA binding#GO:0003677 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000002739.3|UniProtKB=G3QJU7 G3QJU7 AP4M1 PTHR10529:SF270 AP COMPLEX SUBUNIT MU AP-4 COMPLEX SUBUNIT MU-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 lysosomal transport#GO:0007041;localization#GO:0051179;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;post-Golgi vesicle-mediated transport#GO:0006892;protein targeting#GO:0006605;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 Golgi apparatus#GO:0005794;AP-type membrane coat adaptor complex#GO:0030119;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular organelle#GO:0043229;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000014916.3|UniProtKB=G3RG16 G3RG16 CPN2 PTHR45617:SF101 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH ALPHA-2-GLYCOPROTEIN cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of vasculature development#GO:1901342;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;epithelium development#GO:0060429;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;tissue development#GO:0009888;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;response to wounding#GO:0009611;positive regulation of cellular process#GO:0048522;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;regulation of angiogenesis#GO:0045765;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of anatomical structure morphogenesis#GO:0022603;morphogenesis of an epithelium#GO:0002009;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;wound healing#GO:0042060;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;positive regulation of angiogenesis#GO:0045766;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022754.2|UniProtKB=G3RMB5 G3RMB5 RAMAC PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-N7 METHYLTRANSFERASE ACTIVATING SUBUNIT-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;RNA binding#GO:0003723;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000016244.3|UniProtKB=G3RJF4 G3RJF4 MFAP2 PTHR16485:SF3 MICROFIBRILLAR-ASSOCIATED PROTEIN 2 MICROFIBRILLAR-ASSOCIATED PROTEIN 2 embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;sensory organ development#GO:0007423;embryo development#GO:0009790;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;visual system development#GO:0150063;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;supramolecular fiber#GO:0099512;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000000695.3|UniProtKB=G3QEI8 G3QEI8 PTHR11006:SF51 PROTEIN ARGININE N-METHYLTRANSFERASE HISTONE-ARGININE METHYLTRANSFERASE CARM1 N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000025468.2|UniProtKB=G3SEX0 G3SEX0 HIPK3 PTHR24058:SF53 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713;transcription corepressor activity#GO:0003714;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transcription coregulator activity#GO:0003712;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 smoothened signaling pathway#GO:0007224;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;intrinsic apoptotic signaling pathway#GO:0097193;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;signaling#GO:0023052;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;positive regulation of macromolecule metabolic process#GO:0010604 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 protein modifying enzyme#PC00260 GORGO|Gene=NDUFA7|UniProtKB=Q0MQA7 Q0MQA7 NDUFA7 PTHR12485:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 7 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007146.3|UniProtKB=G3QW56 G3QW56 PLXNA4 PTHR22625:SF34 PLEXIN PLEXIN-A4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 anatomical structure development#GO:0048856;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of plasma membrane bounded cell projection organization#GO:0120035;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;axon guidance#GO:0007411;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;synapse assembly#GO:0007416;cell development#GO:0048468;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;positive regulation of multicellular organismal process#GO:0051240;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;neuron differentiation#GO:0030182;positive regulation of cell differentiation#GO:0045597;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of nervous system development#GO:0051960;system development#GO:0048731;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cell adhesion#GO:0007162;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;positive regulation of axonogenesis#GO:0050772;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of multicellular organismal development#GO:2000026;cell projection morphogenesis#GO:0048858;regulation of axonogenesis#GO:0050770;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009768.3|UniProtKB=G3R2T3 G3R2T3 TMX1 PTHR46107:SF2 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 1 oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000037978.1|UniProtKB=A0A2I2ZXZ5 A0A2I2ZXZ5 PTHR22599:SF51 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB FAMILY MEMBER 4, PHOCEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000016502.3|UniProtKB=G3RK43 G3RK43 PTHR11937:SF196 ACTIN ACTIN-LIKE PROTEIN 6B chromatin binding#GO:0003682;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;protein acetyltransferase complex#GO:0031248;ATPase complex#GO:1904949;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromatin#GO:0000785;nucleus#GO:0005634;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000028211.2|UniProtKB=G3SH35 G3SH35 LOC101125487 PTHR16206:SF12 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 1A regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558 transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000043474.1|UniProtKB=A0A2I2YYF3 A0A2I2YYF3 PTHR45828:SF51 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007571.3|UniProtKB=G3QX75 G3QX75 OAZ1 PTHR10279:SF8 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 1 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000005204.3|UniProtKB=G3SD99 G3SD99 OVGP1 PTHR11177:SF248 CHITINASE OVIDUCT-SPECIFIC GLYCOPROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000001059.3|UniProtKB=G3QFH1 G3QFH1 KRTCAP3 PTHR31258:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 3 KERATINOCYTE-ASSOCIATED PROTEIN 3 GORGO|Ensembl=ENSGGOG00000007225.3|UniProtKB=A0A2I2YC48 A0A2I2YC48 ERBIN PTHR45752:SF47 LEUCINE-RICH REPEAT-CONTAINING ERBIN regulation of innate immune response#GO:0045088;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006921.3|UniProtKB=G3QVJ8 G3QVJ8 PLA2G5 PTHR11716:SF10 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 GROUP V catalytic activity#GO:0003824;phospholipid binding#GO:0005543;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;cation binding#GO:0043169;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094;carboxylic ester hydrolase activity#GO:0052689;A2-type glycerophospholipase activity#GO:0004623;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;metal ion binding#GO:0046872;lipid binding#GO:0008289;binding#GO:0005488;calcium ion binding#GO:0005509 negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663;metabolic process#GO:0008152;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;regulation of T cell activation#GO:0050863;negative regulation of cell-cell adhesion#GO:0022408;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;cellular process#GO:0009987;regulation of mononuclear cell proliferation#GO:0032944;regulation of lymphocyte activation#GO:0051249;glycerolipid metabolic process#GO:0046486;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;negative regulation of cell activation#GO:0050866;lipid metabolic process#GO:0006629;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;negative regulation of cell adhesion#GO:0007162;negative regulation of cell population proliferation#GO:0008285;organophosphate metabolic process#GO:0019637;regulation of cell population proliferation#GO:0042127;negative regulation of T cell activation#GO:0050868;negative regulation of leukocyte cell-cell adhesion#GO:1903038;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;phosphatidylglycerol metabolic process#GO:0046471;regulation of T cell proliferation#GO:0042129;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000034881.2|UniProtKB=A0A2I2Y7D7 A0A2I2Y7D7 ST7L PTHR12745:SF4 SUPPRESSION OF TUMORIGENICITY 7 SUPPRESSOR OF TUMORIGENICITY 7 PROTEIN-LIKE GORGO|Ensembl=ENSGGOG00000002057.3|UniProtKB=G3QI29 G3QI29 ALAS2 PTHR13693:SF58 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, ERYTHROID-SPECIFIC, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;heme biosynthetic process#GO:0006783;primary metabolic process#GO:0044238;pigment metabolic process#GO:0042440;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;porphyrin-containing compound biosynthetic process#GO:0006779;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000002755.3|UniProtKB=A0A2I2ZM29 A0A2I2ZM29 DNAJC18 PTHR43908:SF2 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 18 heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;cellular response to misfolded protein#GO:0071218 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000013615.3|UniProtKB=A0A2I2ZLY1 A0A2I2ZLY1 PTHR13677:SF2 LD41638P PROTEIN DENND6B molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;recycling endosome#GO:0055037;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000038907.1|UniProtKB=A0A2I2Y413 A0A2I2Y413 LMLN PTHR10942:SF0 LEISHMANOLYSIN-LIKE PEPTIDASE LEISHMANOLYSIN-LIKE PEPTIDASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000005378.3|UniProtKB=G3QRL0 G3QRL0 PTHR11486:SF20 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 7 signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104 cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;tube development#GO:0035295;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;animal organ development#GO:0048513 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 Fructose galactose metabolism#P02744>Galactokinase#P02960;FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000002026.3|UniProtKB=G3QI08 G3QI08 GLI3 PTHR45718:SF5 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTION ACTIVATOR GLI3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Hedgehog signaling pathway#P00025>Cubitus interruptus repressor#P00687;Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 GORGO|Ensembl=ENSGGOG00000036417.1|UniProtKB=A0A2I2YF83 A0A2I2YF83 LOC101126920 PTHR21859:SF50 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31D3-RELATED GORGO|Ensembl=ENSGGOG00000038914.1|UniProtKB=A0A2I2YQM2 A0A2I2YQM2 PTHR23267:SF388 IMMUNOGLOBULIN LIGHT CHAIN NON-FUNCTIONAL IMMUNOGLOBULIN KAPPA VARIABLE 1D-42-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000520.3|UniProtKB=G3QE26 G3QE26 LSG1 PTHR45709:SF6 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED LARGE SUBUNIT GTPASE 1 HOMOLOG ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000041670.1|UniProtKB=A0A2I2ZVF8 A0A2I2ZVF8 COA6 PTHR46690:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035 protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000016991.3|UniProtKB=G3RLD9 G3RLD9 SPRY4 PTHR12365:SF6 SPROUTY PROTEIN SPROUTY HOMOLOG 4 molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of intracellular signal transduction#GO:1902532;regulation of Ras protein signal transduction#GO:0046578;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>SPRY#G01511;EGF receptor signaling pathway#P00018>Spry#P00541;FGF signaling pathway#P00021>Spry#P00626 GORGO|Gene=WFDC12|UniProtKB=A4K2R5 A4K2R5 WFDC12 PTHR19441:SF42 WAP four-disulfide core domain protein WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 12 endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to external stimulus#GO:0009605;defense response#GO:0006952;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000027594.2|UniProtKB=A0A2I2Z252 A0A2I2Z252 LOC101148063 PTHR33968:SF1 PROTEIN PET100 HOMOLOG, MITOCHONDRIAL PROTEIN PET100 HOMOLOG, MITOCHONDRIAL mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;chaperone-mediated protein complex assembly#GO:0051131 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743 GORGO|Gene=MT-ATP6|UniProtKB=Q9T9Y7 Q9T9Y7 MT-ATP6 PTHR11410:SF0 ATP SYNTHASE SUBUNIT A ATP SYNTHASE F(0) COMPLEX SUBUNIT A channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;transporter activity#GO:0005215 ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ATP synthase#PC00002;primary active transporter#PC00068 ATP synthesis#P02721>ATP synthetase F0#P02797 GORGO|Ensembl=ENSGGOG00000013605.3|UniProtKB=G3S329 G3S329 NKX2-3 PTHR24340:SF32 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000000560.3|UniProtKB=G3QE65 G3QE65 RASAL3 PTHR10194:SF96 RAS GTPASE-ACTIVATING PROTEINS RAS PROTEIN ACTIVATOR LIKE-3 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000005924.3|UniProtKB=G3SK88 G3SK88 LOC101127788 PTHR11860:SF4 POLYMERIC-IMMUNOGLOBULIN RECEPTOR TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN TMIGD3 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune system process#GO:0002376;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000027922.2|UniProtKB=A0A2I2ZWH7 A0A2I2ZWH7 PTHR10369:SF43 60S RIBOSOMAL PROTEIN L36A/L44 60S RIBOSOMAL PROTEIN L36A-LIKE structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000525.3|UniProtKB=G3QE33 G3QE33 SLC26A5 PTHR11814:SF32 SULFATE TRANSPORTER PRESTIN carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 chloride transport#GO:0006821;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;establishment of localization#GO:0051234;system process#GO:0003008;cellular process#GO:0009987;multicellular organismal process#GO:0032501;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;dicarboxylic acid transport#GO:0006835;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;sensory perception of sound#GO:0007605 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000044128.1|UniProtKB=G3RBI6 G3RBI6 PTHR21245:SF4 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN DEAD END PROTEIN HOMOLOG 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;RNA stabilization#GO:0043489;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;positive regulation of biosynthetic process#GO:0009891;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007083.3|UniProtKB=G3QVZ1 G3QVZ1 CWC25 PTHR16196:SF0 CELL CYCLE CONTROL PROTEIN CWF25 PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Gene=TAS2R14|UniProtKB=Q645Z2 Q645Z2 TAS2R14 PTHR11394:SF23 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 14 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004165.3|UniProtKB=G3QNH2 G3QNH2 PTHR14907:SF6 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000007294.3|UniProtKB=A0A2I2YJ09 A0A2I2YJ09 ATP6V1B1 PTHR43389:SF1 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, KIDNEY ISOFORM intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;cation-transporting ATPase complex#GO:0090533;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;apical part of cell#GO:0045177;proton-transporting two-sector ATPase complex#GO:0016469;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 ATP synthase#PC00002;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000038346.1|UniProtKB=A0A2I2YE08 A0A2I2YE08 POP4 PTHR13348:SF0 RIBONUCLEASE P SUBUNIT P29 RIBONUCLEASE P PROTEIN SUBUNIT P29 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;ribonuclease P complex#GO:0030677;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000041212.1|UniProtKB=A0A2I2Z3S3 A0A2I2Z3S3 GPR3 PTHR22750:SF39 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 3 transmembrane signaling receptor activity#GO:0004888;bioactive lipid receptor activity#GO:0045125;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000004310.3|UniProtKB=A0A2I2ZWN2 A0A2I2ZWN2 COL2A1 PTHR24023:SF58 COLLAGEN ALPHA COLLAGEN ALPHA-1(II) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 skeletal system morphogenesis#GO:0048705;cellular process#GO:0009987;multicellular organismal process#GO:0032501;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;animal organ morphogenesis#GO:0009887;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;system development#GO:0048731 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000014665.3|UniProtKB=G3RFE1 G3RFE1 ADAT1 PTHR46516:SF1 TRNA-SPECIFIC ADENOSINE DEAMINASE 1 TRNA-SPECIFIC ADENOSINE DEAMINASE 1 deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;hydrolase activity#GO:0016787;tRNA-specific adenosine deaminase activity#GO:0008251 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000039665.1|UniProtKB=A0A2I2YNZ6 A0A2I2YNZ6 PTHR46595:SF5 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000000795.3|UniProtKB=G3QET3 G3QET3 TTYH2 PTHR12424:SF6 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 2 gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016167.3|UniProtKB=G3RJ93 G3RJ93 LNX2 PTHR19964:SF33 MULTIPLE PDZ DOMAIN PROTEIN LIGAND OF NUMB PROTEIN X 2 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096 scaffold/adaptor protein#PC00226 Notch signaling pathway#P00045>LNXp80#P01111 GORGO|Ensembl=ENSGGOG00000012369.3|UniProtKB=G3R9I4 G3R9I4 SULT2B1 PTHR11783:SF9 SULFOTRANSFERASE SULT SULFOTRANSFERASE 2B1 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000037053.1|UniProtKB=A0A2I2Y8P7 A0A2I2Y8P7 FZD4 PTHR11309:SF23 FRIZZLED FRIZZLED-4 signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 signaling#GO:0023052;visual system development#GO:0150063;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;non-canonical Wnt signaling pathway#GO:0035567;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;retina development in camera-type eye#GO:0060041;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;sensory system development#GO:0048880;vasculature development#GO:0001944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;sensory organ development#GO:0007423 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 GORGO|Ensembl=ENSGGOG00000010256.3|UniProtKB=G3R419 G3R419 KIF25 PTHR24115:SF421 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF25 isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000010277.3|UniProtKB=G3R441 G3R441 MALSU1 PTHR21043:SF0 IOJAP SUPERFAMILY ORTHOLOG MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1 binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;ribosomal large subunit binding#GO:0043023;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022 ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial large ribosomal subunit assembly#GO:1902775;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex organization#GO:0043933;mitochondrial ribosome assembly#GO:0061668;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosomal large subunit assembly#GO:0000027;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000026338.2|UniProtKB=G3RU01 G3RU01 CEACAM6 PTHR44337:SF24 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM6 cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000012611.3|UniProtKB=G3RA47 G3RA47 ATP5PO PTHR11910:SF1 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT OSCP, MITOCHONDRIAL monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252 carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000025939.2|UniProtKB=G3S078 G3S078 RIMKLA PTHR21621:SF1 RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN N-ACETYLASPARTYLGLUTAMATE SYNTHASE A catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000038841.1|UniProtKB=A0A2I2YUA2 A0A2I2YUA2 PTHR11767:SF24 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 16 transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000014710.3|UniProtKB=G3S8U9 G3S8U9 HSD17B11 PTHR24322:SF489 PKSB ESTRADIOL 17-BETA-DEHYDROGENASE 11 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000015779.3|UniProtKB=G3RI99 G3RI99 KCNMB2 PTHR10258:SF5 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-2 transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 detection of chemical stimulus#GO:0009593;action potential#GO:0001508;metal ion transport#GO:0030001;response to stimulus#GO:0050896;nervous system process#GO:0050877;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;response to calcium ion#GO:0051592;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;detection of stimulus#GO:0051606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;potassium ion transport#GO:0006813;transport#GO:0006810;response to metal ion#GO:0010038;system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000022464.2|UniProtKB=G3SDA0 G3SDA0 RPA3 PTHR15114:SF1 REPLICATION PROTEIN A3 REPLICATION PROTEIN A 14 KDA SUBUNIT DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mismatch repair#GO:0006298;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;cellular process#GO:0009987 intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;replication fork#GO:0005657;replisome#GO:0030894;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-DNA complex#GO:0032993;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;site of double-strand break#GO:0035861;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 Cell cycle#P00013>Pre-replication Complex#P00478 GORGO|Ensembl=ENSGGOG00000000248.3|UniProtKB=G3QDD2 G3QDD2 DPYS PTHR11647:SF50 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;dihydropyrimidinase activity#GO:0004157;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 GORGO|Ensembl=ENSGGOG00000012991.3|UniProtKB=G3RB34 G3RB34 HIGD1B PTHR12297:SF9 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1B cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000036326.1|UniProtKB=A0A2I2Y773 A0A2I2Y773 QRSL1 PTHR11895:SF149 TRANSAMIDASE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on RNA#GO:0140098 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000008970.3|UniProtKB=G3R0S3 G3R0S3 ABRACL PTHR46334:SF1 COSTARS FAMILY PROTEIN ABRACL COSTARS FAMILY PROTEIN ABRACL regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000000829.3|UniProtKB=A0A2I2ZB55 A0A2I2ZB55 CCM2 PTHR21642:SF4 CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN cellular process#GO:0009987;heart development#GO:0007507;vasculogenesis#GO:0001570;multicellular organismal process#GO:0032501;tube development#GO:0035295;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;vasculature development#GO:0001944;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cell differentiation#GO:0030154;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731 EGF receptor signaling pathway#P00018>MEKK1-5#P00553 GORGO|Ensembl=ENSGGOG00000011341.3|UniProtKB=G3R6T9 G3R6T9 RIMBP2 PTHR14234:SF18 RIM BINDING PROTEIN-RELATED RIMS-BINDING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of localization#GO:0032879;regulation of transport#GO:0051049 intracellular anatomical structure#GO:0005622;presynaptic active zone#GO:0048786;cell junction#GO:0030054;cytoplasm#GO:0005737;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;presynapse#GO:0098793;cell cortex#GO:0005938 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000759.3|UniProtKB=G3QEQ0 G3QEQ0 PLCB2 PTHR10336:SF10 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-2 hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;signal transduction#GO:0007165;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;metabolic process#GO:0008152;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;organophosphate metabolic process#GO:0019637;establishment of localization#GO:0051234;phosphatidylinositol metabolic process#GO:0046488;transport#GO:0006810;lipid metabolic process#GO:0006629;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Wnt signaling pathway#P00057>Phospholipase C#P01443;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Endogenous cannabinoid signaling#P05730>PLC#P05746;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Endothelin signaling pathway#P00019>PLCbeta#P00591;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744 GORGO|Ensembl=ENSGGOG00000010284.3|UniProtKB=G3R451 G3R451 PHGDH PTHR42938:SF22 FORMATE DEHYDROGENASE 1 D-3-PHOSPHOGLYCERATE DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;oxidoreductase#PC00176 Serine glycine biosynthesis#P02776>Phosphoglycerate dehydrogenase#P03160 GORGO|Ensembl=ENSGGOG00000009955.3|UniProtKB=G3R393 G3R393 PTHR23349:SF62 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST MUSCULIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;muscle tissue development#GO:0060537;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;skeletal muscle tissue development#GO:0007519;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;muscle organ development#GO:0007517 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013081.3|UniProtKB=G3RZC6 G3RZC6 C2CD5 PTHR37412:SF2 C2 DOMAIN-CONTAINING PROTEIN 5 C2 DOMAIN-CONTAINING PROTEIN 5 calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;lipid binding#GO:0008289;metal ion binding#GO:0046872;phospholipid binding#GO:0005543 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;establishment of protein localization#GO:0045184;positive regulation of biological process#GO:0048518;regulation of localization#GO:0032879;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;intracellular protein transmembrane transport#GO:0065002;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein localization to cell periphery#GO:1990778;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;protein localization to membrane#GO:0072657;protein transport#GO:0015031;regulation of protein localization#GO:0032880;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;transmembrane transport#GO:0055085;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;regulation of cellular process#GO:0050794;protein localization to plasma membrane#GO:0072659;regulation of transmembrane transport#GO:0034762;regulation of establishment of protein localization#GO:0070201;localization#GO:0051179;localization within membrane#GO:0051668 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012894.3|UniProtKB=A0A2I2ZBS2 A0A2I2ZBS2 PTHR43011:SF1 IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169;metal ion binding#GO:0046872;iron ion binding#GO:0005506 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000007389.3|UniProtKB=G3QWS0 G3QWS0 SLC2A4 PTHR23503:SF120 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 response to hormone#GO:0009725;D-glucose transmembrane transport#GO:1904659;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;carbohydrate transmembrane transport#GO:0034219;cellular response to nitrogen compound#GO:1901699;response to peptide hormone#GO:0043434;transport#GO:0006810;cellular response to insulin stimulus#GO:0032869;import into cell#GO:0098657;establishment of localization#GO:0051234;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;import across plasma membrane#GO:0098739;cellular response to hormone stimulus#GO:0032870;vitamin transport#GO:0051180;cellular response to peptide hormone stimulus#GO:0071375;cellular response to chemical stimulus#GO:0070887;carbohydrate transport#GO:0008643;response to oxygen-containing compound#GO:1901700;localization#GO:0051179;transmembrane transport#GO:0055085;response to nitrogen compound#GO:1901698 intracellular anatomical structure#GO:0005622;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000040510.1|UniProtKB=A0A2I2ZST3 A0A2I2ZST3 ENHO PTHR38492:SF1 ADROPIN ADROPIN positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;positive regulation of response to stimulus#GO:0048584;positive regulation of Notch signaling pathway#GO:0045747;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;positive regulation of signaling#GO:0023056 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000039612.1|UniProtKB=A0A2I2ZJ25 A0A2I2ZJ25 ABCB4 PTHR24221:SF241 ATP-BINDING CASSETTE SUB-FAMILY B PHOSPHATIDYLCHOLINE TRANSLOCATOR ABCB4 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transmembrane transporter activity#GO:0022857;intramembrane lipid carrier activity#GO:0140303;phosphatidylcholine intramembrane carrier activity#GO:0008525;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085;lipid localization#GO:0010876 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000002525.3|UniProtKB=G3QJ99 G3QJ99 STPG4 PTHR35678:SF1 PROTEIN STPG4 PROTEIN STPG4 chromatin binding#GO:0003682;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular process#GO:0009987;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009778.3|UniProtKB=G3R2T9 G3R2T9 RNASEK PTHR31733:SF1 RIBONUCLEASE KAPPA RIBONUCLEASE KAPPA monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;proton-transporting two-sector ATPase complex#GO:0016469;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000013258.3|UniProtKB=G3RBS0 G3RBS0 PON3 PTHR11799:SF14 PARAOXONASE SERUM PARAOXONASE_LACTONASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to toxic substance#GO:0009636;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Gene=TAS2R1|UniProtKB=Q646G7 Q646G7 TAS2R1 PTHR11394:SF149 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 1 bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016715.3|UniProtKB=G3S6N1 G3S6N1 LOC109028795 PTHR48018:SF147 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015222.3|UniProtKB=G3RGT9 G3RGT9 PTHR19297:SF81 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 3 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000013202.3|UniProtKB=G3RBL6 G3RBL6 NAT8 PTHR13947:SF48 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 8-RELATED N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000039267.1|UniProtKB=G3SEH8 G3SEH8 LOC101132256 PTHR23428:SF167 HISTONE H2B HISTONE H2B TYPE 3-B antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000009491.3|UniProtKB=G3R241 G3R241 PROS1 PTHR24040:SF0 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN VITAMIN K-DEPENDENT PROTEIN S regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of coagulation#GO:0050818;negative regulation of coagulation#GO:0050819 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Blood coagulation#P00011>PS#P00412 GORGO|Ensembl=ENSGGOG00000009501.3|UniProtKB=G3R243 G3R243 PTHR12268:SF13 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Gene=SLC35G5|UniProtKB=Q0Q7U7 Q0Q7U7 SLC35G5 PTHR22911:SF32 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G4-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006290.3|UniProtKB=G3QTW6 G3QTW6 LBX2 PTHR24336:SF10 TRANSCRIPTION FACTOR LBX TRANSCRIPTION FACTOR LBX2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000008646.2|UniProtKB=A0A2I2YDU5 A0A2I2YDU5 GJB7 PTHR11984:SF26 CONNEXIN GAP JUNCTION BETA-7 PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 regulation of biological process#GO:0050789;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell communication#GO:0007154 cell junction#GO:0030054;anchoring junction#GO:0070161;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 cell junction protein#PC00070;gap junction#PC00105 GORGO|Ensembl=ENSGGOG00000000631.3|UniProtKB=G3QEC9 G3QEC9 C5H6orf141 PTHR36880:SF1 9130008F23RIK PROTEIN 9130008F23RIK PROTEIN GORGO|Ensembl=ENSGGOG00000010748.3|UniProtKB=G3R5A7 G3R5A7 ZNF524 PTHR24390:SF109 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 524 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004552.3|UniProtKB=G3QWD5 G3QWD5 ZNF430 PTHR23226:SF398 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 72 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014781.3|UniProtKB=G3RFQ6 G3RFQ6 CNTN2 PTHR13817:SF81 TITIN CONTACTIN-2 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000006292.3|UniProtKB=G3QTW8 G3QTW8 LOC101125570 PTHR34524:SF2 CALCYPHOSIN CALCYPHOSIN calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000006430.3|UniProtKB=G3QU93 G3QU93 ECI2 PTHR43684:SF17 FAMILY NOT NAMED ENOYL-COA DELTA ISOMERASE 2 intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;microbody#GO:0042579;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007134.3|UniProtKB=G3QW37 G3QW37 KATNB1 PTHR19845:SF0 KATANIN P80 SUBUNIT KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1 microtubule depolymerization#GO:0007019;protein depolymerization#GO:0051261;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;cellular component disassembly#GO:0022411;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000041860.1|UniProtKB=A0A2I2ZBU0 A0A2I2ZBU0 LOC101151609 PTHR48615:SF7 LATE CORNIFIED ENVELOPE PROTEIN 1C LATE CORNIFIED ENVELOPE PROTEIN 2A-RELATED GORGO|Ensembl=ENSGGOG00000002841.3|UniProtKB=G3RNU4 G3RNU4 NEUROG1 PTHR19290:SF130 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;forebrain development#GO:0030900;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule metabolic process#GO:0010604;head development#GO:0060322;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000023164.2|UniProtKB=A0A2I2Z9U3 A0A2I2Z9U3 PTHR11820:SF105 ACYLPYRUVASE OXALOACETATE TAUTOMERASE FAHD1, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000008418.3|UniProtKB=G3QZB9 G3QZB9 PROK1 PTHR18821:SF7 PROKINETICIN PROKINETICIN-1 endothelial cell proliferation#GO:0001935;epithelial cell proliferation#GO:0050673;cell population proliferation#GO:0008283;cellular process#GO:0009987 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000000393.3|UniProtKB=G3QDR0 G3QDR0 PTHR46105:SF2 AGAP004733-PA NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000026703.2|UniProtKB=G3S019 G3S019 PTHR48002:SF104 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000042709.1|UniProtKB=A0A2I2YWK5 A0A2I2YWK5 PTHR43612:SF6 TRIFUNCTIONAL ENZYME SUBUNIT ALPHA ENOYL-COA HYDRATASE intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000038845.1|UniProtKB=A0A2I2Y8R5 A0A2I2Y8R5 PTHR48030:SF2 SPLICING FACTOR 3B SUBUNIT 4 SPLICING FACTOR 3B SUBUNIT 4 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000014005.3|UniProtKB=A0A2I2YDM3 A0A2I2YDM3 NHSL3 PTHR23039:SF6 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 3 GORGO|Ensembl=ENSGGOG00000043707.1|UniProtKB=A0A2I2YDZ8 A0A2I2YDZ8 PTHR15853:SF2 THIOREDOXIN-RELATED THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 2 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;head development#GO:0060322;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;brain development#GO:0007420 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane contact site#GO:0044232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000034987.2|UniProtKB=G3SKJ9 G3SKJ9 PABIR1 PTHR22227:SF14 FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1 PPP2R1A-PPP2R2A-INTERACTING PHOSPHATASE REGULATOR 1 protein serine/threonine phosphatase inhibitor activity#GO:0004865;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein metabolic process#GO:0051247;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009033.3|UniProtKB=G3RT01 G3RT01 MAGIX PTHR47646:SF1 PDZ DOMAIN-CONTAINING PROTEIN MAGIX PDZ DOMAIN-CONTAINING PROTEIN MAGIX GORGO|Ensembl=ENSGGOG00000013554.3|UniProtKB=G3RCI8 G3RCI8 KCTD14 PTHR14499:SF3 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD14 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013250.3|UniProtKB=G3SIJ9 G3SIJ9 HNRNPR PTHR21245:SF5 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008058.3|UniProtKB=G3QYE5 G3QYE5 GPR78 PTHR24245:SF7 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 78 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000004272.3|UniProtKB=G3QNS1 G3QNS1 EPB41 PTHR23280:SF12 4.1 G PROTEIN PROTEIN 4.1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 Nicotine pharmacodynamics pathway#P06587>EPB41#P06607;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 GORGO|Ensembl=ENSGGOG00000000091.3|UniProtKB=G3RMD4 G3RMD4 USP45 PTHR24006:SF858 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000001226.3|UniProtKB=G3QFX4 G3QFX4 MAFB PTHR10129:SF10 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFB binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of myeloid cell differentiation#GO:0045637;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of hemopoiesis#GO:1903706;regulation of cell development#GO:0060284;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell differentiation#GO:0045595;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000043299.1|UniProtKB=A0A2I2Y323 A0A2I2Y323 PTHR10562:SF131 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 2-RELATED enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein binding#GO:0005515 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 p53 pathway#P00059>Sumo-1 ligase#P04635 GORGO|Ensembl=ENSGGOG00000006147.3|UniProtKB=G3QTI7 G3QTI7 HAND2 PTHR23349:SF41 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;heart development#GO:0007507;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000014303.3|UniProtKB=G3REH2 G3REH2 NTRK2 PTHR24416:SF136 TYROSINE-PROTEIN KINASE RECEPTOR BDNF_NT-3 GROWTH FACTORS RECEPTOR catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular response to nerve growth factor stimulus#GO:1990090;neurogenesis#GO:0022008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399 organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuron projection terminus#GO:0044306;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron spine#GO:0044309;postsynapse#GO:0098794;dendritic spine#GO:0043197;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;axon terminus#GO:0043679;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001978.3|UniProtKB=G3QHV9 G3QHV9 PRR11 PTHR23330:SF9 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED PROLINE-RICH PROTEIN 11 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002541.4|UniProtKB=G3QJC2 G3QJC2 ADAMTS20 PTHR13723:SF165 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 20 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000008232.3|UniProtKB=G3QYV1 G3QYV1 PTHR16099:SF5 8-OXO-DGTP DIPHOSPHATES NUDT15 NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15 GORGO|Ensembl=ENSGGOG00000037618.1|UniProtKB=A0A2I2ZPB9 A0A2I2ZPB9 PTHR19367:SF5 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-3 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000000475.3|UniProtKB=G3QDY7 G3QDY7 LOC101134978 PTHR13391:SF1 MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO PROTEIN MISATO HOMOLOG 1 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000004085.3|UniProtKB=G3QN96 G3QN96 TMEM156 PTHR14788:SF5 TRANSMEMBRANE PROTEIN 156 TRANSMEMBRANE PROTEIN 156 GORGO|Ensembl=ENSGGOG00000007500.3|UniProtKB=G3QX21 G3QX21 CCDC158 PTHR47615:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 GORGO|Ensembl=ENSGGOG00000042218.1|UniProtKB=A0A2I2YI11 A0A2I2YI11 TMEM167A PTHR13229:SF2 PROTEIN KISH-A PROTEIN KISH-A transport#GO:0006810;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;protein secretion#GO:0009306;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;macromolecule localization#GO:0033036;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;establishment of protein localization#GO:0045184;export from cell#GO:0140352 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000002538.3|UniProtKB=G3QJB2 G3QJB2 PLPPR2 PTHR10165:SF15 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;dephosphorylation#GO:0016311;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000034983.2|UniProtKB=G3SKW2 G3SKW2 PTHR12756:SF5 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 4 exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;protein binding#GO:0005515;metallocarboxypeptidase activity#GO:0004181;carboxypeptidase activity#GO:0004180;binding#GO:0005488;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;metalloexopeptidase activity#GO:0008235 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000006714.3|UniProtKB=G3QV17 G3QV17 GCLC PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000025458.2|UniProtKB=A0A2I2ZUG9 A0A2I2ZUG9 CSNK2A2 PTHR24054:SF34 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA' phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of chromosome segregation#GO:0051983;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of chromosome separation#GO:1905818;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459 GORGO|Ensembl=ENSGGOG00000022898.2|UniProtKB=G3S8A3 G3S8A3 ZPBP2 PTHR15443:SF4 ZONA PELLUCIDA BINDING PROTEIN SP38 ZONA PELLUCIDA-BINDING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000011465.3|UniProtKB=G3R759 G3R759 SELENON PTHR16213:SF78 SELENOPROTEIN N SELENOPROTEIN N skeletal muscle organ development#GO:0060538;calcium ion homeostasis#GO:0055074;animal gross anatomical part developmental process#GO:0160108;inorganic ion homeostasis#GO:0098771;striated muscle cell development#GO:0055002;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cell development#GO:0048468;muscle organ development#GO:0007517;chemical homeostasis#GO:0048878;striated muscle tissue development#GO:0014706;animal organ development#GO:0048513;regulation of release of sequestered calcium ion into cytosol#GO:0051279;striated muscle cell differentiation#GO:0051146;regulation of localization#GO:0032879;regulation of transport#GO:0051049;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;regulation of transmembrane transport#GO:0034762;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of metal ion transport#GO:0010959;homeostatic process#GO:0042592;regulation of monoatomic cation transmembrane transport#GO:1904062;monoatomic cation homeostasis#GO:0055080;developmental process#GO:0032502;cellular developmental process#GO:0048869;skeletal muscle tissue development#GO:0007519;tissue development#GO:0009888;regulation of monoatomic ion transport#GO:0043269;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000040325.1|UniProtKB=A0A2I2YTF1 A0A2I2YTF1 EFCAB2 PTHR46763:SF1 DYNEIN REGULATORY COMPLEX PROTEIN 8 DYNEIN REGULATORY COMPLEX PROTEIN 8 sperm principal piece#GO:0097228;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000013402.3|UniProtKB=A0A2I2YD67 A0A2I2YD67 MBD2 PTHR12396:SF5 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 2 negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;constitutive heterochromatin formation#GO:0140719;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338 histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000007263.3|UniProtKB=A0A2I2ZEE4 A0A2I2ZEE4 FAM184B PTHR18870:SF8 PROTEIN TAG-278-RELATED PROTEIN FAM184B GORGO|Ensembl=ENSGGOG00000003248.3|UniProtKB=G3RW55 G3RW55 PTHR14162:SF1 MUCOSAL ADDRESSIN CELL ADHESION MOLECULE-1 MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1 cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515 signaling#GO:0023052;response to stimulus#GO:0050896;heterotypic cell-cell adhesion#GO:0034113;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;integrin-mediated signaling pathway#GO:0007229;cell communication#GO:0007154;cell adhesion#GO:0007155;immune system process#GO:0002376;biological regulation#GO:0065007;cell migration#GO:0016477;signal transduction#GO:0007165;leukocyte cell-cell adhesion#GO:0007159;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell surface receptor signaling pathway#GO:0007166;leukocyte migration#GO:0050900 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000001005.3|UniProtKB=G3QFC1 G3QFC1 USF3 PTHR46970:SF1 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016233.3|UniProtKB=G3RJE7 G3RJE7 MED20 PTHR12465:SF0 UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000004219.3|UniProtKB=G3QNL8 G3QNL8 RAD1 PTHR10870:SF0 CELL CYCLE CHECKPOINT PROTEIN RAD1 CELL CYCLE CHECKPOINT PROTEIN RAD1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 negative regulation of cell cycle#GO:0045786;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA integrity checkpoint signaling#GO:0031570;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 GORGO|Ensembl=ENSGGOG00000015314.3|UniProtKB=G3RH24 G3RH24 NUDC PTHR12356:SF3 NUCLEAR MOVEMENT PROTEIN NUDC NUCLEAR MIGRATION PROTEIN NUDC primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000023018.2|UniProtKB=G3SBX6 G3SBX6 PTHR31848:SF2 REFILIN-A-RELATED REFILIN-B negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;multicellular organism development#GO:0007275;animal organ development#GO:0048513;skeletal system morphogenesis#GO:0048705;regulation of cell development#GO:0060284;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of bone mineralization#GO:0030500;animal gross anatomical part developmental process#GO:0160108;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;system development#GO:0048731;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of developmental process#GO:0050793 GORGO|Ensembl=ENSGGOG00000009459.3|UniProtKB=G3R204 G3R204 OBP2B PTHR11430:SF129 LIPOCALIN ODORANT-BINDING PROTEIN 2A-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000013943.3|UniProtKB=G3RDJ2 G3RDJ2 THAP10 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000015311.3|UniProtKB=G3RH19 G3RH19 NR0B2 PTHR24081:SF0 NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B MEMBER 2 DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription coregulator activity#GO:0003712 negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;rhythmic process#GO:0048511;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C4 zinc finger nuclear receptor#PC00169;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010386.3|UniProtKB=G3RX25 G3RX25 GJA8 PTHR11984:SF19 CONNEXIN GAP JUNCTION ALPHA-8 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 establishment of localization#GO:0051234;cell communication#GO:0007154;localization#GO:0051179;transport#GO:0006810;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of biological process#GO:0050789 anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 gap junction#PC00105;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000001574.3|UniProtKB=A0A2I2ZF53 A0A2I2ZF53 CCDC28B PTHR13400:SF2 CHEMOKINE C-C MOTIF RECEPTOR 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 28B organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013543.3|UniProtKB=G3RCH9 G3RCH9 LOC101138755 PTHR26453:SF57 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007123.3|UniProtKB=G3RY54 G3RY54 SRPX PTHR46343:SF1 HYR DOMAIN-CONTAINING PROTEIN SUSHI REPEAT-CONTAINING PROTEIN SRPX organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;lysosome organization#GO:0007040;cellular component assembly#GO:0022607;phagocytosis#GO:0006909;phagolysosome assembly#GO:0001845;transport#GO:0006810;lytic vacuole organization#GO:0080171;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular component organization#GO:0016043;endocytosis#GO:0006897;organelle assembly#GO:0070925;localization#GO:0051179;vacuole organization#GO:0007033 GORGO|Ensembl=ENSGGOG00000001807.3|UniProtKB=G3QHF3 G3QHF3 RAMP3 PTHR14076:SF2 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 3 coreceptor activity#GO:0015026;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;establishment of protein localization#GO:0045184;response to hormone#GO:0009725;receptor internalization#GO:0031623;calcium ion transport#GO:0006816;import into cell#GO:0098657;protein localization to cell periphery#GO:1990778;signaling#GO:0023052;endocytosis#GO:0006897;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;monoatomic ion transport#GO:0006811;protein transport#GO:0015031;cellular localization#GO:0051641;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005914.3|UniProtKB=G3QSY6 G3QSY6 NUCB2 PTHR19237:SF22 NUCLEOBINDIN NUCLEOBINDIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000041957.1|UniProtKB=G3S775 G3S775 LOC101129878 PTHR48425:SF1 KERATIN-ASSOCIATED PROTEIN 2-1 KERATIN-ASSOCIATED PROTEIN 2-1 GORGO|Ensembl=ENSGGOG00000008656.3|UniProtKB=G3RXP9 G3RXP9 NR2F2 PTHR24083:SF45 NUCLEAR HORMONE RECEPTOR COUP TRANSCRIPTION FACTOR 2 molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;ion binding#GO:0043167;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;organic acid binding#GO:0043177;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;lipid binding#GO:0008289;carboxylic acid binding#GO:0031406;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000036991.1|UniProtKB=A0A2I2YHS5 A0A2I2YHS5 PTHR45841:SF3 MRNA TURNOVER PROTEIN 4 MRTO4 RIBOSOME ASSEMBLY FACTOR MRT4 rRNA processing#GO:0006364;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000001872.3|UniProtKB=G3RWA2 G3RWA2 PLPP1 PTHR10165:SF26 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;signal transduction#GO:0007165;lipid modification#GO:0030258;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;cell communication#GO:0007154;dephosphorylation#GO:0016311 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000026126.2|UniProtKB=G3RUB0 G3RUB0 INTS5 PTHR31697:SF2 INTEGRATOR COMPLEX SUBUNIT 5 INTEGRATOR COMPLEX SUBUNIT 5 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;snRNA processing#GO:0016180;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;integrator complex#GO:0032039;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000013781.3|UniProtKB=G3RND3 G3RND3 LOC101152160 PTHR11738:SF165 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 1-RELATED transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;regulation of immune response#GO:0050776;cell communication#GO:0007154;response to peptide#GO:1901652 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000024394.2|UniProtKB=G3SHD2 G3SHD2 CREB1 PTHR45879:SF1 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;intracellular signaling cassette#GO:0141124;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Apoptosis signaling pathway#P00006>ATF#P00302;p38 MAPK pathway#P05918>CREB#P06027;Enkephalin release#P05913>CREB#P05971;Gonadotropin-releasing hormone receptor pathway#P06664>CREB#P06749;CCKR signaling map#P06959>CREB1#P07232;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 GORGO|Ensembl=ENSGGOG00000044081.1|UniProtKB=A0A2I2Z0C9 A0A2I2Z0C9 KLHDC7A PTHR45972:SF1 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 7A GORGO|Ensembl=ENSGGOG00000043575.1|UniProtKB=A0A2I2ZXB0 A0A2I2ZXB0 PTHR11362:SF111 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PEBP1 regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000010143.3|UniProtKB=A0A2I2Z6F1 A0A2I2Z6F1 PTHR12064:SF27 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;monoatomic ion homeostasis#GO:0050801 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000028207.2|UniProtKB=G3S0B7 G3S0B7 SHISA5 PTHR31395:SF14 SHISA PROTEIN SHISA-5 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000017133.3|UniProtKB=G3RLQ5 G3RLQ5 TRIM71 PTHR24104:SF55 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM71 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;RNA binding#GO:0003723;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;nucleic acid binding#GO:0003676;binding#GO:0005488;acyltransferase activity#GO:0016746 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;post-transcriptional regulation of gene expression#GO:0010608;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011139.3|UniProtKB=A0A2I2YML7 A0A2I2YML7 CRHBP PTHR10278:SF0 CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN CORTICOTROPIN-RELEASING HORMONE-BINDING PROTEIN hormone binding#GO:0042562;binding#GO:0005488;peptide hormone binding#GO:0017046 negative regulation of cellular process#GO:0048523;regulation of system process#GO:0044057;biological regulation#GO:0065007;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;regulation of cell communication#GO:0010646;negative regulation of multicellular organismal process#GO:0051241;cellular response to stimulus#GO:0051716;regulation of transport#GO:0051049;regulation of localization#GO:0032879;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;hormone-mediated signaling pathway#GO:0009755;regulation of hormone secretion#GO:0046883;negative regulation of cell communication#GO:0010648;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000024357.2|UniProtKB=G3S2H6 G3S2H6 FXR2 PTHR10603:SF3 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN RNA-BINDING PROTEIN FXR2 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of mRNA stability#GO:0043488;positive regulation of nervous system development#GO:0051962;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;regulation of trans-synaptic signaling#GO:0099177;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;animal organ development#GO:0048513;regulation of mRNA metabolic process#GO:1903311;positive regulation of cell differentiation#GO:0045597;regulation of cell communication#GO:0010646;positive regulation of neurogenesis#GO:0050769;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;regulation of developmental process#GO:0050793;modulation of chemical synaptic transmission#GO:0050804;RNA localization#GO:0006403;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;regulation of neurogenesis#GO:0050767;regulation of RNA metabolic process#GO:0051252;positive regulation of translation#GO:0045727;nucleic acid transport#GO:0050657;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;nitrogen compound transport#GO:0071705;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;regulation of translation#GO:0006417;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;regulation of neuronal synaptic plasticity#GO:0048168;transport#GO:0006810;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;post-transcriptional regulation of gene expression#GO:0010608;regulation of synaptic plasticity#GO:0048167 cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;neuron projection#GO:0043005;nucleus#GO:0005634;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228 translational protein#PC00263;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000002690.3|UniProtKB=G3SI65 G3SI65 CRISPLD2 PTHR10334:SF64 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN LCCL DOMAIN-CONTAINING 2 binding#GO:0005488;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367 head development#GO:0060322;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000011484.3|UniProtKB=G3R771 G3R771 B4GALT4 PTHR19300:SF9 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 4 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000039784.1|UniProtKB=A0A2I2YN60 A0A2I2YN60 FBXO17 PTHR12125:SF7 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 17 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000009485.3|UniProtKB=G3R257 G3R257 DNAJC13 PTHR36983:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000006813.3|UniProtKB=G3QVA8 G3QVA8 ACAD8 PTHR43831:SF1 ISOBUTYRYL-COA DEHYDROGENASE ISOBUTYRYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000003673.3|UniProtKB=A0A2I2YN67 A0A2I2YN67 FOXD4 PTHR11829:SF420 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-LIKE 3-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000000765.3|UniProtKB=G3QEQ5 G3QEQ5 KNSTRN PTHR31940:SF2 SMALL KINETOCHORE-ASSOCIATED PROTEIN SMALL KINETOCHORE-ASSOCIATED PROTEIN microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;nuclear division#GO:0000280;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of biological process#GO:0050789;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;mitotic spindle#GO:0072686;centriolar satellite#GO:0034451;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule end#GO:1990752;kinetochore#GO:0000776;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000000947.3|UniProtKB=A0A2I2YCJ7 A0A2I2YCJ7 ZNF790 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 519 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013331.3|UniProtKB=A0A2I2ZGD7 A0A2I2ZGD7 PTHR14248:SF38 CYCLIN Y, ISOFORM A CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009743.3|UniProtKB=G3R2Q9 G3R2Q9 NT5DC4 PTHR12103:SF18 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 4 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824 purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000041152.1|UniProtKB=A0A2I2ZHP2 A0A2I2ZHP2 MEI4 PTHR28575:SF1 MEIOSIS-SPECIFIC PROTEIN MEI4 MEIOSIS-SPECIFIC PROTEIN MEI4 homologous chromosome pairing at meiosis#GO:0007129;oogenesis#GO:0048477;meiotic DNA double-strand break formation#GO:0042138;organelle organization#GO:0006996;cellular process#GO:0009987;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome segregation#GO:0007059;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;nuclear division#GO:0000280;male gamete generation#GO:0048232;nucleobase-containing compound metabolic process#GO:0006139;cellular developmental process#GO:0048869;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;developmental process#GO:0032502;spermatogenesis#GO:0007283;reproductive process#GO:0022414;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;germ cell development#GO:0007281;organelle fission#GO:0048285;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;synaptonemal structure#GO:0099086;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793 GORGO|Ensembl=ENSGGOG00000021932.2|UniProtKB=G3SBF3 G3SBF3 PTHR10129:SF25 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFF cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of epithelial cell differentiation#GO:0030856;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cell differentiation#GO:0045595;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000024322.2|UniProtKB=G3S845 G3S845 GPR174 PTHR24232:SF86 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 174-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000026429.2|UniProtKB=G3RWC2 G3RWC2 STAMBPL1 PTHR12947:SF7 AMSH-LIKE PROTEASE AMSH-LIKE PROTEASE peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824 positive regulation of TOR signaling#GO:0032008;localization#GO:0051179;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of signal transduction#GO:0009967;regulation of TORC1 signaling#GO:1903432;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;transport#GO:0006810;intracellular transport#GO:0046907;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;endosome transport via multivesicular body sorting pathway#GO:0032509;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;positive regulation of TORC1 signaling#GO:1904263;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;late endosome to vacuole transport#GO:0045324;regulation of biological process#GO:0050789;endosomal transport#GO:0016197;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000005471.3|UniProtKB=G3QRU4 G3QRU4 ARL2BP PTHR15487:SF5 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003443.3|UniProtKB=G3QLM4 G3QLM4 FSAF1 PTHR28366:SF1 CHROMOSOME 1 OPEN READING FRAME 131 40S SMALL SUBUNIT PROCESSOME ASSEMBLY FACTOR 1 GORGO|Ensembl=ENSGGOG00000001311.3|UniProtKB=A0A2I2YA17 A0A2I2YA17 PTHR11761:SF23 50S/60S RIBOSOMAL PROTEIN L14/L23 60S RIBOSOMAL PROTEIN L23 binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000007503.3|UniProtKB=A0A2I2ZVY3 A0A2I2ZVY3 DSCC1 PTHR13395:SF6 SISTER CHROMATID COHESION PROTEIN DCC1-RELATED SISTER CHROMATID COHESION PROTEIN DCC1 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic sister chromatid cohesion#GO:0007064;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276 chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 GORGO|Ensembl=ENSGGOG00000012802.3|UniProtKB=G3RQV0 G3RQV0 LOC101153360 PTHR16675:SF164 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN E antigen binding#GO:0003823;peptide binding#GO:0042277;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Gene=GPR34|UniProtKB=Q6XCF2 Q6XCF2 GPR34 PTHR24233:SF1 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 34-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000013160.3|UniProtKB=A0A2I2ZRR3 A0A2I2ZRR3 GNE PTHR18964:SF176 ROK (REPRESSOR, ORF, KINASE) FAMILY BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;isomerase activity#GO:0016853;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;transferase activity#GO:0016740;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;carbohydrate kinase activity#GO:0019200 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000010891.3|UniProtKB=G3R5P5 G3R5P5 MYO1G PTHR13140:SF381 MYOSIN UNCONVENTIONAL MYOSIN-IG catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;cellular process#GO:0009987;actin filament-based movement#GO:0030048;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;actin filament-based process#GO:0030029;transport#GO:0006810 actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000004929.3|UniProtKB=G3QQG7 G3QQG7 MARCHF6 PTHR13145:SF0 SSM4 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MARCHF6 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000011935.3|UniProtKB=G3R8E4 G3R8E4 ELMO3 PTHR12771:SF16 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 3 supramolecular fiber organization#GO:0097435;cell chemotaxis#GO:0060326;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;actin filament-based process#GO:0030029;response to stimulus#GO:0050896;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;locomotion#GO:0040011;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;response to external stimulus#GO:0009605;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012797.3|UniProtKB=G3RAJ8 G3RAJ8 GUCA1A PTHR23055:SF13 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 1 cyclase regulator activity#GO:0010851;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;molecular function activator activity#GO:0140677;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234 visual perception#GO:0007601;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;photoreceptor inner segment#GO:0001917 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000002011.3|UniProtKB=G3QHZ1 G3QHZ1 APOL1 PTHR14096:SF55 APOLIPOPROTEIN L APOLIPOPROTEIN L1 binding#GO:0005488;lipid binding#GO:0008289 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000001347.3|UniProtKB=A0A2I2YPY3 A0A2I2YPY3 ARHGAP22 PTHR15228:SF22 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 22 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of synapse structure or activity#GO:0050803;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of small GTPase mediated signal transduction#GO:0051056;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000002910.3|UniProtKB=G3QK91 G3QK91 DGAT2 PTHR12317:SF14 DIACYLGLYCEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;neutral lipid metabolic process#GO:0006638 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000012452.3|UniProtKB=G3SGN9 G3SGN9 STARD10 PTHR19308:SF7 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN START DOMAIN-CONTAINING PROTEIN 10 cytosol#GO:0005829;cell-cell junction#GO:0005911;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000025367.2|UniProtKB=A0A2I2YVZ3 A0A2I2YVZ3 RACK1 PTHR19868:SF0 RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1 SMALL RIBOSOMAL SUBUNIT PROTEIN RACK1 kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 translation#GO:0006412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of translation#GO:0017148;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;rescue of stalled cytosolic ribosome#GO:0072344;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;negative regulation of metabolic process#GO:0009892;translational elongation#GO:0006414;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;gene expression#GO:0010467 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000010.3|UniProtKB=G3QCR6 G3QCR6 ST6GALNAC1 PTHR45941:SF1 ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2-LIKE-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;oligosaccharide metabolic process#GO:0009311;multicellular organismal-level homeostasis#GO:0048871;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biological process involved in interspecies interaction between organisms#GO:0044419;carbohydrate metabolic process#GO:0005975;homeostatic process#GO:0042592;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;oligosaccharide biosynthetic process#GO:0009312;homeostasis of number of cells#GO:0048872 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000000160.3|UniProtKB=G3QD52 G3QD52 RFWD3 PTHR16047:SF7 RFWD3 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RFWD3 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000014041.3|UniProtKB=G3RDT0 G3RDT0 GPR61 PTHR22752:SF5 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 61 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009254.3|UniProtKB=G3R1H3 G3R1H3 OR4C6 PTHR48002:SF128 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000028.3|UniProtKB=G3QCT1 G3QCT1 LOC101142648 PTHR42968:SF9 WD REPEAT-CONTAINING WD REPEAT-CONTAINING PROTEIN 87 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027587.2|UniProtKB=G3QKY6 G3QKY6 LOC101153366 PTHR11571:SF245 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE A5 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824 modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;glutathione metabolic process#GO:0006749 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000012725.3|UniProtKB=G3RAD8 G3RAD8 GAPT PTHR37350:SF1 PROTEIN GAPT PROTEIN GAPT leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;multicellular organismal-level homeostasis#GO:0048871;B cell activation#GO:0042113;leukocyte proliferation#GO:0070661;lymphocyte homeostasis#GO:0002260;cellular process#GO:0009987;lymphocyte activation involved in immune response#GO:0002285;immune response#GO:0006955;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;lymphocyte proliferation#GO:0046651;B cell proliferation#GO:0042100;B cell activation involved in immune response#GO:0002312;immune system process#GO:0002376;cell activation#GO:0001775;cell population proliferation#GO:0008283;homeostasis of number of cells#GO:0048872;cell activation involved in immune response#GO:0002263;leukocyte activation#GO:0045321;response to stimulus#GO:0050896;mononuclear cell proliferation#GO:0032943;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000001816.4|UniProtKB=A0A2I2ZHC6 A0A2I2ZHC6 TIAL1 PTHR24012:SF733 RNA BINDING PROTEIN TIA1 CYTOTOXIC GRANULE-ASSOCIATED RNA BINDING PROTEIN-LIKE 1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;poly(A) binding#GO:0008143;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;single-stranded RNA binding#GO:0003727 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;cytosol#GO:0005829;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000025384.2|UniProtKB=A0A2I2ZU16 A0A2I2ZU16 KLHL13 PTHR45632:SF7 LD33804P KELCH-LIKE PROTEIN 13 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell cycle#GO:0051726;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026923.2|UniProtKB=G3SEB2 G3SEB2 CDKN1C PTHR10265:SF44 CYCLIN-DEPENDENT KINASE INHIBITOR 1 CYCLIN-DEPENDENT KINASE INHIBITOR 1C molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase inhibitor activity#GO:0019210 regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of mitotic cell cycle#GO:0007346;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 kinase modulator#PC00140;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000012017.3|UniProtKB=G3R8M8 G3R8M8 CCDC171 PTHR37476:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 171 COILED-COIL DOMAIN-CONTAINING PROTEIN 171 GORGO|Ensembl=ENSGGOG00000027261.2|UniProtKB=G3SGW2 G3SGW2 PTHR12735:SF40 BOLA-LIKE PROTEIN-RELATED BOLA-LIKE PROTEIN 2 binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000028011.2|UniProtKB=G3RTN3 G3RTN3 DCUN1D5 PTHR12281:SF6 RP42 RELATED DCN1-LIKE PROTEIN 5 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787 regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of protein modification process#GO:0031399 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002490.3|UniProtKB=G3QJ68 G3QJ68 CRABP2 PTHR11955:SF152 FATTY ACID BINDING PROTEIN CELLULAR RETINOIC ACID-BINDING PROTEIN 2 fatty acid binding#GO:0005504;lipid binding#GO:0008289;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;organic acid binding#GO:0043177 lipid localization#GO:0010876;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;lipid transport#GO:0006869 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000038925.1|UniProtKB=A0A2I2Z5V0 A0A2I2Z5V0 ZNF662 PTHR24390:SF39 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 662 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004215.3|UniProtKB=G3QNM2 G3QNM2 TMC5 PTHR23302:SF5 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000025950.2|UniProtKB=A0A2I2Z6P2 A0A2I2Z6P2 TMEM213 PTHR36293:SF1 TRANSMEMBRANE PROTEIN 213 TRANSMEMBRANE PROTEIN 213 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000007949.3|UniProtKB=G3QY71 G3QY71 KMT2D PTHR45888:SF2 HL01030P-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE 2D catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone H3K4 methyltransferase activity#GO:0042800;histone H3 methyltransferase activity#GO:0140938;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;transcription coactivator activity#GO:0003713;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;transcription regulator activity#GO:0140110;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000011186.3|UniProtKB=G3R6G3 G3R6G3 CCHCR1 PTHR46822:SF1 COILED-COIL ALPHA-HELICAL ROD PROTEIN 1 COILED-COIL ALPHA-HELICAL ROD PROTEIN 1 nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000041353.1|UniProtKB=A0A2I2Y8M0 A0A2I2Y8M0 PTHR31283:SF14 EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER L ANTIGEN FAMILY MEMBER 3 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000026489.2|UniProtKB=G3SDB4 G3SDB4 MPDU1 PTHR12226:SF5 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;oligosaccharide biosynthetic process#GO:0009312;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000005889.3|UniProtKB=G3QSX5 G3QSX5 IFT140 PTHR15722:SF7 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intraciliary transport particle A#GO:0030991;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000038965.1|UniProtKB=A0A2I2ZWP1 A0A2I2ZWP1 GCSAM PTHR35351:SF2 GERMINAL CENTER-ASSOCIATED SIGNALING AND MOTILITY-LIKE PROTEIN GERMINAL CENTER-ASSOCIATED SIGNALING AND MOTILITY PROTEIN negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;regulation of signal transduction#GO:0009966;negative regulation of locomotion#GO:0040013;regulation of locomotion#GO:0040012;regulation of cell motility#GO:2000145;regulation of lymphocyte migration#GO:2000401;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of leukocyte migration#GO:0002685;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of B cell receptor signaling pathway#GO:0050855;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000008344.3|UniProtKB=G3QZ58 G3QZ58 TM9SF2 PTHR10766:SF55 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2 localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;localization within membrane#GO:0051668;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011334.3|UniProtKB=A0A2I2Y808 A0A2I2Y808 C5H6orf136 PTHR31094:SF2 RIKEN CDNA 2310061I04 GENE RIKEN CDNA 2310061I04 GENE GORGO|Ensembl=ENSGGOG00000004916.3|UniProtKB=G3QQF1 G3QQF1 GARS1 PTHR10745:SF0 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 GLYCINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000012859.3|UniProtKB=G3RAR5 G3RAR5 AGR2 PTHR15337:SF1 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 2 HOMOLOG response to stress#GO:0006950;inflammatory response#GO:0006954;response to stimulus#GO:0050896;defense response#GO:0006952 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000005874.3|UniProtKB=G3QSU8 G3QSU8 FFAR2 PTHR45822:SF5 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 2 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to fatty acid#GO:0070542;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to fatty acid#GO:0071398;biological regulation#GO:0065007;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000011129.3|UniProtKB=A0A2I2ZMW9 A0A2I2ZMW9 SEC11A PTHR10806:SF28 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11A catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 serine protease#PC00203 Endothelin signaling pathway#P00019>signal peptidase#P00573;Vasopressin synthesis#P04395>Signal Peptidase#P04589 GORGO|Ensembl=ENSGGOG00000015197.3|UniProtKB=G3RGS3 G3RGS3 SASH3 PTHR12301:SF5 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM AND SH3 DOMAIN-CONTAINING PROTEIN 3 regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;positive regulation of leukocyte proliferation#GO:0070665;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of lymphocyte proliferation#GO:0050670;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of cell activation#GO:0050867;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte proliferation#GO:0050671;regulation of immune response#GO:0050776;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of B cell proliferation#GO:0030890;regulation of cell communication#GO:0010646;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of B cell proliferation#GO:0030888;positive regulation of leukocyte activation#GO:0002696;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;regulation of B cell activation#GO:0050864;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of adaptive immune response#GO:0002821;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002513.3|UniProtKB=G3RUY3 G3RUY3 SYNPR PTHR10306:SF16 SYNAPTOPHYSIN SYNAPTOPORIN intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013112.3|UniProtKB=G3RBE1 G3RBE1 PTGIR PTHR11866:SF7 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTACYCLIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 negative regulation of cellular process#GO:0048523;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;negative regulation of cell population proliferation#GO:0008285;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 GORGO|Ensembl=ENSGGOG00000011071.3|UniProtKB=G3R652 G3R652 PJVK PTHR16399:SF10 GASDERMIN PEJVAKIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008942.3|UniProtKB=G3R0P9 G3R0P9 PTHR22957:SF255 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 22A enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000024713.2|UniProtKB=G3RZ13 G3RZ13 PTHR11486:SF74 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 19 fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 response to fibroblast growth factor#GO:0071774;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 GORGO|Ensembl=ENSGGOG00000004580.3|UniProtKB=G3QPJ3 G3QPJ3 YWHAB PTHR18860:SF28 14-3-3 PROTEIN 14-3-3 PROTEIN BETA_ALPHA scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;Parkinson disease#P00049>14-3-3#P01238;CCKR signaling map#P06959>14-3-3 beta/alpha#P07038 GORGO|Ensembl=ENSGGOG00000009488.3|UniProtKB=G3R227 G3R227 GNA12 PTHR10218:SF130 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-12 G protein-coupled receptor binding#GO:0001664;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;signaling receptor binding#GO:0005102;binding#GO:0005488;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;protein binding#GO:0005515 biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186 extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;apical part of cell#GO:0045177;cytoplasmic side of membrane#GO:0098562;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;brush border membrane#GO:0031526;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;brush border#GO:0005903;cell projection membrane#GO:0031253;side of membrane#GO:0098552;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;apical plasma membrane#GO:0016324;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797 heterotrimeric G-protein#PC00117;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000017151.3|UniProtKB=A0A2I2ZJC3 A0A2I2ZJC3 JCAD PTHR34757:SF1 JUNCTIONAL PROTEIN ASSOCIATED WITH CORONARY ARTERY DISEASE JUNCTIONAL CADHERIN 5-ASSOCIATED PROTEIN regulation of cell population proliferation#GO:0042127;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;biological regulation#GO:0065007;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell projection membrane#GO:0031253;anchoring junction#GO:0070161;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;cell leading edge#GO:0031252;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;ruffle#GO:0001726;adherens junction#GO:0005912;ruffle membrane#GO:0032587 GORGO|Ensembl=ENSGGOG00000016371.3|UniProtKB=G3RJU1 G3RJU1 CATSPERG PTHR14327:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT GAMMA cation channel complex#GO:0034703;transporter complex#GO:1990351;membrane#GO:0016020;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;plasma membrane#GO:0005886;cilium#GO:0005929;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000027348.2|UniProtKB=A0A2I2Y5E5 A0A2I2Y5E5 MMADHC PTHR13192:SF3 MY011 PROTEIN COBALAMIN TRAFFICKING PROTEIN CBLD metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000036792.1|UniProtKB=A0A2I2Z847 A0A2I2Z847 SERTM2 PTHR35660:SF2 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000013106.4|UniProtKB=G3RBD3 G3RBD3 CLEC2D PTHR45710:SF41 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER D signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;immune response-activating signaling pathway#GO:0002757;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;T cell activation#GO:0042110;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;cell communication#GO:0007154;immune system process#GO:0002376;cell activation#GO:0001775;regulation of immune response#GO:0050776 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000009466.3|UniProtKB=G3R210 G3R210 ART1 PTHR10339:SF19 ADP-RIBOSYLTRANSFERASE GPI-LINKED NAD(P)(+)--ARGININE ADP-RIBOSYLTRANSFERASE 1 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001646.3|UniProtKB=G3QH08 G3QH08 SLC5A11 PTHR11819:SF171 SOLUTE CARRIER FAMILY 5 SODIUM_MYO-INOSITOL COTRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000023226.2|UniProtKB=G3RPC6 G3RPC6 OR1P1 PTHR26453:SF626 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000039686.1|UniProtKB=A0A2I2Y4U5 A0A2I2Y4U5 PTHR46107:SF4 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN DOMAIN-CONTAINING PROTEIN oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011918.3|UniProtKB=G3R8B9 G3R8B9 PTHR12619:SF24 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000041311.1|UniProtKB=G3SK09 G3SK09 CD59 PTHR36288:SF1 SIMILAR TO RIKEN CDNA A930018P22 SIMILAR TO HUMAN CHROMOSOME 11 OPEN READING FRAME 91 GORGO|Ensembl=ENSGGOG00000041528.1|UniProtKB=G3S3T1 G3S3T1 LOC101133653 PTHR26453:SF271 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2V1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001373.3|UniProtKB=G3QGA4 G3QGA4 CNPY3 PTHR15382:SF2 CTG4A-RELATED PROTEIN CANOPY HOMOLOG 3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 GORGO|Ensembl=ENSGGOG00000025528.2|UniProtKB=G3RRL9 G3RRL9 SEPSECS PTHR12944:SF2 SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 translation#GO:0006412;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;protein biosynthetic process#GO:0160307;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;metabolic process#GO:0008152;translational elongation#GO:0006414;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467 GORGO|Ensembl=ENSGGOG00000008437.3|UniProtKB=G3QZD5 G3QZD5 RAB40B PTHR47980:SF46 LD44762P SMALL MONOMERIC GTPASE ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;exocytosis#GO:0006887;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;localization#GO:0051179;protein metabolic process#GO:0019538;secretion#GO:0046903;secretion by cell#GO:0032940;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;export from cell#GO:0140352 membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000008340.3|UniProtKB=G3S5K9 G3S5K9 YTHDF1 PTHR12357:SF65 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;protein-RNA adaptor activity#GO:0140517;RNA binding#GO:0003723 positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;organelle assembly#GO:0070925;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cytoplasmic stress granule assembly#GO:0034063;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000040630.1|UniProtKB=A0A2I2YEQ8 A0A2I2YEQ8 LOC101127397 PTHR47831:SF1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2A-RELATED nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000009518.3|UniProtKB=G3R255 G3R255 LOC101148069 PTHR46945:SF4 CYSTATIN-9-LIKE CYSTATIN-9 defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;immune system process#GO:0002376;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000025836.2|UniProtKB=A0A2I2YG59 A0A2I2YG59 LOC101144731 PTHR11489:SF17 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2-RELATED structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006445.3|UniProtKB=G3QUA8 G3QUA8 CEP164 PTHR18902:SF27 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED CENTROSOMAL PROTEIN OF 164 KDA cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;ciliary transition fiber#GO:0097539;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000004902.3|UniProtKB=G3QQE1 G3QQE1 RASGEF1A PTHR23113:SF172 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1A enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000041396.1|UniProtKB=A0A2I2ZUS0 A0A2I2ZUS0 BIRC6 PTHR46116:SF39 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME DUAL E2 UBIQUITIN-CONJUGATING ENZYME_E3 UBIQUITIN-PROTEIN LIGASE BIRC6 ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001166.3|UniProtKB=G3QFS1 G3QFS1 TRAFD1 PTHR16295:SF19 TRAF-TYPE ZINC FINGER PROTEIN-RELATED TRAF-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of innate immune response#GO:0045824;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of response to external stimulus#GO:0032102;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;regulation of response to biotic stimulus#GO:0002831;regulation of defense response#GO:0031347;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011524.3|UniProtKB=G3R7B2 G3R7B2 DZIP1L PTHR21502:SF8 ZINC FINGER PROTEIN DZIP1 CILIUM ASSEMBLY PROTEIN DZIP1L cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000016890.3|UniProtKB=G3RL42 G3RL42 TRIM11 PTHR24103:SF648 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM11 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of biological process#GO:0050789;immune system process#GO:0002376;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;defense response to symbiont#GO:0140546;immune response#GO:0006955;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023548.2|UniProtKB=G3RN95 G3RN95 LOC101126269 PTHR23299:SF49 METALLOTHIONEIN METALLOTHIONEIN-1A cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 cellular response to chemical stimulus#GO:0070887;inorganic ion homeostasis#GO:0098771;intracellular monoatomic ion homeostasis#GO:0006873;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;homeostatic process#GO:0042592;response to cadmium ion#GO:0046686;response to metal ion#GO:0010038;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;detoxification of inorganic compound#GO:0061687;cellular process#GO:0009987;response to chemical#GO:0042221;detoxification#GO:0098754 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000007223.3|UniProtKB=G3QWB0 G3QWB0 MLEC PTHR13460:SF0 FAMILY NOT NAMED MALECTIN carbohydrate binding#GO:0030246;binding#GO:0005488 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;primary metabolic process#GO:0044238;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000023582.2|UniProtKB=G3S8F3 G3S8F3 HOXB5 PTHR45659:SF2 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000027201.2|UniProtKB=G3SHY9 G3SHY9 EIF1 PTHR10388:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1 translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488;nucleic acid binding#GO:0003676 ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000002428.3|UniProtKB=A0A2I2ZMV5 A0A2I2ZMV5 BIN3 PTHR47174:SF3 BRIDGING INTEGRATOR 3 BRIDGING INTEGRATOR 3 lipid binding#GO:0008289;binding#GO:0005488 transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endocytosis#GO:0006897 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000022187.2|UniProtKB=G3S2G1 G3S2G1 CIMIP7 PTHR35539:SF1 CDNA SEQUENCE BC048562 CILIARY MICROTUBULE INNER PROTEIN 7 GORGO|Ensembl=ENSGGOG00000005866.3|UniProtKB=G3QSU2 G3QSU2 SEC61G PTHR12309:SF5 SEC61 GAMMA SUBUNIT PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transmembrane protein transporter activity#GO:0008320 intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of protein localization to endoplasmic reticulum#GO:0072599;localization within membrane#GO:0051668;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;rough endoplasmic reticulum#GO:0005791;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000008841.3|UniProtKB=A0A2I2YY31 A0A2I2YY31 PHLPP2 PTHR45752:SF10 LEUCINE-RICH REPEAT-CONTAINING PH DOMAIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN PHOSPHATASE 2 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022476.2|UniProtKB=G3S7M2 G3S7M2 LOC101128022 PTHR21859:SF52 ACROSOME-SPECIFIC PROTEIN SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000013256.3|UniProtKB=G3RBR7 G3RBR7 GRK7 PTHR24355:SF12 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RHODOPSIN KINASE GRK7 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 GORGO|Ensembl=ENSGGOG00000001770.4|UniProtKB=G3QHB8 G3QHB8 SLC22A16 PTHR24064:SF186 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 16 quaternary ammonium group transmembrane transporter activity#GO:0015651;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000017022.3|UniProtKB=G3RLG6 G3RLG6 OGFR PTHR14015:SF1 OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR OPIOID GROWTH FACTOR RECEPTOR transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009960.3|UniProtKB=G3R3A1 G3R3A1 HEY1 PTHR10985:SF78 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN 1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of neuron differentiation#GO:0045664;regulation of nucleobase-containing compound metabolic process#GO:0019219;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 GORGO|Ensembl=ENSGGOG00000009735.3|UniProtKB=G3R2P8 G3R2P8 METTL16 PTHR13393:SF0 SAM-DEPENDENT METHYLTRANSFERASE RNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL16 catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;nucleobase-containing compound biosynthetic process#GO:0034654;post-transcriptional regulation of gene expression#GO:0010608;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;RNA processing#GO:0006396;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000036562.1|UniProtKB=A0A2I2ZAR9 A0A2I2ZAR9 PTHR24073:SF1050 DRAB5-RELATED RAB5A, MEMBER RAS ONCOGENE FAMILY hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of biological process#GO:0050789;protein transport#GO:0015031;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;localization#GO:0051179;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;import into cell#GO:0098657;regulation of neuronal synaptic plasticity#GO:0048168;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;regulation of synaptic plasticity#GO:0048167 endosome#GO:0005768;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;early endosome#GO:0005769;endocytic vesicle#GO:0030139;intracellular vesicle#GO:0097708;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;secretory vesicle#GO:0099503;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000012090.3|UniProtKB=G3R8S6 G3R8S6 MMP24 PTHR10201:SF138 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-24 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141 GORGO|Ensembl=ENSGGOG00000015691.3|UniProtKB=G3RI23 G3RI23 RGMA PTHR31428:SF4 RGM DOMAIN FAMILY MEMBER DRAG-1 REPULSIVE GUIDANCE MOLECULE A coreceptor activity#GO:0015026;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000012032.3|UniProtKB=G3RTD0 G3RTD0 EIF5A PTHR11673:SF34 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-1 translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000026711.2|UniProtKB=G3S1W7 G3S1W7 TEX13B PTHR23111:SF94 ZINC FINGER PROTEIN TESTIS-EXPRESSED PROTEIN 13B RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 GORGO|Ensembl=ENSGGOG00000039720.1|UniProtKB=A0A2I2Z8K8 A0A2I2Z8K8 PTHR46576:SF1 BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000038644.1|UniProtKB=A0A2I2ZXA5 A0A2I2ZXA5 ZNF584 PTHR24377:SF611 IP01015P-RELATED ZINC FINGER PROTEIN 584 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016646.3|UniProtKB=G3RKI8 G3RKI8 DYNC2I1 PTHR16022:SF0 WD REPEAT DOMAIN 60 CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;spindle pole#GO:0000922;dynein complex#GO:0030286;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000001449.3|UniProtKB=G3QGH5 G3QGH5 ROBO1 PTHR10075:SF137 BASIGIN RELATED ROUNDABOUT GUIDANCE RECEPTOR 1 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000036457.1|UniProtKB=A0A2I2ZP02 A0A2I2ZP02 C7H8orf88 PTHR12669:SF15 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN CHROMOSOME 8 OPEN READING FRAME 88 translation regulator activity#GO:0045182;protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000012907.3|UniProtKB=A0A2I2ZWM5 A0A2I2ZWM5 MDM2 PTHR46858:SF13 OS05G0521000 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MDM2 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of apoptotic process#GO:0042981;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;negative regulation of signal transduction#GO:0009968;positive regulation of cell cycle#GO:0045787;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of intrinsic apoptotic signaling pathway#GO:2001242;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 p53 pathway feedback loops 2#P04398>MDM-2#G04709;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#G04674;P53 pathway feedback loops 1#P04392>Mdm2#P04536;P53 pathway feedback loops 1#P04392>MDM-2#G04682;p53 pathway#P00059>Mdm2#P01483;Ubiquitin proteasome pathway#P00060>E3#P01490;p53 pathway#P00059>MDM-2#G01563;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#P04496;p53 pathway feedback loops 2#P04398>Mdm2#P04663 GORGO|Ensembl=ENSGGOG00000006523.3|UniProtKB=G3QUI4 G3QUI4 SLC26A3 PTHR11814:SF19 SULFATE TRANSPORTER CHLORIDE ANION EXCHANGER carboxylic acid transmembrane transporter activity#GO:0046943;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310 transport#GO:0006810;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015342.3|UniProtKB=G3RH65 G3RH65 ZFYVE26 PTHR35478:SF1 ZINC FINGER FYVE DOMAIN PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 26 GORGO|Ensembl=ENSGGOG00000025141.2|UniProtKB=G3S6H9 G3S6H9 FAM8A1 PTHR13659:SF5 AUTOSOMAL HIGHLY CONSERVED PROTEIN PROTEIN FAM8A1 GORGO|Ensembl=ENSGGOG00000009163.3|UniProtKB=A0A2I2ZUY0 A0A2I2ZUY0 TECTB PTHR14002:SF13 ENDOGLIN/TGF-BETA RECEPTOR TYPE III BETA-TECTORIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000954.3|UniProtKB=A0A2I2ZBJ8 A0A2I2ZBJ8 CNTRL PTHR34491:SF173 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED CENTRIOLIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016574.3|UniProtKB=G3RKC1 G3RKC1 DNMT1 PTHR10629:SF61 CYTOSINE-SPECIFIC METHYLTRANSFERASE DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;nucleic acid binding#GO:0003676;binding#GO:0005488;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;DNA binding#GO:0003677 negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA methyltransferase#PC00013;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000034904.2|UniProtKB=G3SKW8 G3SKW8 LRRC27 PTHR16083:SF3 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 27 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010115.3|UniProtKB=G3R3N8 G3R3N8 ATF4 PTHR13044:SF2 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Apoptosis signaling pathway#P00006>ATF#P00302 GORGO|Ensembl=ENSGGOG00000012924.3|UniProtKB=A0A2K5TIZ6 A0A2K5TIZ6 TBX6 PTHR11267:SF100 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX6 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 GORGO|Ensembl=ENSGGOG00000013960.3|UniProtKB=A0A2I2Y8I4 A0A2I2Y8I4 DHX35 PTHR18934:SF136 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX35-RELATED helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001118.3|UniProtKB=G3QFM3 G3QFM3 PNMT PTHR10867:SF18 NNMT/PNMT/TEMT FAMILY MEMBER PHENYLETHANOLAMINE N-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;N-methyltransferase activity#GO:0008170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 GORGO|Ensembl=ENSGGOG00000002249.3|UniProtKB=G3QIK4 G3QIK4 FRMD6 PTHR13429:SF11 FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY FERM DOMAIN-CONTAINING PROTEIN 6 protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000005723.3|UniProtKB=G3QSH0 G3QSH0 WIPF3 PTHR23331:SF4 CXYORF1 WAS_WASL-INTERACTING PROTEIN FAMILY MEMBER 3 cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;localization within membrane#GO:0051668;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;endocytic recycling#GO:0032456;cytosolic transport#GO:0016482;export from cell#GO:0140352;cellular component organization#GO:0016043;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;endosomal transport#GO:0016197;actin filament organization#GO:0007015;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;retrograde transport, endosome to Golgi#GO:0042147;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 endosome#GO:0005768;intracellular organelle#GO:0043229;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012600.3|UniProtKB=G3RA30 G3RA30 RAB20 PTHR24073:SF941 DRAB5-RELATED RAS-RELATED PROTEIN RAB-20 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;endocytosis#GO:0006897;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;early endosome#GO:0005769 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000023133.2|UniProtKB=G3QMQ3 G3QMQ3 KRT79 PTHR45616:SF10 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 79 structural molecule activity#GO:0005198 keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;epidermis development#GO:0008544;developmental process#GO:0032502;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;skin development#GO:0043588;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000024311.2|UniProtKB=G3RU36 G3RU36 PTHR10792:SF26 60S RIBOSOMAL PROTEIN L24 RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000040995.1|UniProtKB=A0A2I2Y8N1 A0A2I2Y8N1 PTHR10113:SF27 PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;translational termination#GO:0006415;translation#GO:0006412;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 translation factor#PC00223;translation release factor#PC00225 GORGO|Ensembl=ENSGGOG00000022952.2|UniProtKB=G3S9M3 G3S9M3 G3BP1 PTHR10693:SF21 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;mRNA binding#GO:0003729;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;catalytic activity, acting on RNA#GO:0140098 cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840 cytosol#GO:0005829;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000040725.1|UniProtKB=A0A2I2ZLH9 A0A2I2ZLH9 PTHR19343:SF14 T CELL RECEPTOR ALPHA VARIABLE 1-2 IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000004390.3|UniProtKB=G3QP21 G3QP21 LOC101125335 PTHR10609:SF16 BIOTINIDASE-RELATED PANTETHEINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000011740.3|UniProtKB=G3R7V3 G3R7V3 LOC101140776 PTHR19444:SF13 UNC-93 RELATED N-ACETYLGLUCOSAMINE TRANSPORTER UNC93A channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000011985.3|UniProtKB=G3R8H6 G3R8H6 AQP11 PTHR21191:SF7 AQUAPORIN AQUAPORIN-11 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 cellular process#GO:0009987;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;homeostatic process#GO:0042592;biological regulation#GO:0065007;chemical homeostasis#GO:0048878;regulation of anatomical structure size#GO:0090066;cellular homeostasis#GO:0019725;regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000002029.3|UniProtKB=G3QI06 G3QI06 CHCHD7 PTHR46811:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000025492.2|UniProtKB=G3RX35 G3RX35 MTERF2 PTHR15437:SF1 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR 2, MITOCHONDRIAL sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 General transcription regulation#P00023>TTF2#P00661;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 GORGO|Ensembl=ENSGGOG00000010985.3|UniProtKB=A0A2I2ZF50 A0A2I2ZF50 RECQL PTHR13710:SF162 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q1 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386 response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;chromosome#GO:0005694 DNA metabolism protein#PC00009;DNA helicase#PC00011 GORGO|Ensembl=ENSGGOG00000013395.3|UniProtKB=G3RC42 G3RC42 PPP1R26 PTHR15724:SF0 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000005968.3|UniProtKB=A0A2I2Y8E6 A0A2I2Y8E6 DNM2 PTHR11566:SF23 DYNAMIN DYNAMIN-2 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;ribonucleoside triphosphate phosphatase activity#GO:0017111;microtubule binding#GO:0008017;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787 synaptic vesicle recycling#GO:0036465;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;receptor internalization#GO:0031623;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;endocytosis#GO:0006897;establishment of organelle localization#GO:0051656;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;cellular localization#GO:0051641;localization#GO:0051179;organelle localization#GO:0051640 organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000041235.1|UniProtKB=A0A2I2ZVH0 A0A2I2ZVH0 AGTR2 PTHR24228:SF8 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR TYPE-2 ANGIOTENSIN II RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 regulation of anatomical structure size#GO:0090066;defense response#GO:0006952;system process#GO:0003008;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;inflammatory response#GO:0006954;cell communication#GO:0007154;regulation of biological quality#GO:0065008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;vasodilation#GO:0042311;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016503.3|UniProtKB=G3RK54 G3RK54 TNNI3K PTHR24198:SF183 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN PROTEIN KINASE DOMAIN-CONTAINING PROTEIN non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000002231.3|UniProtKB=G3QII3 G3QII3 CTTNBP2NL PTHR23166:SF9 FILAMIN/GPBP-INTERACTING PROTEIN CTTNBP2 N-TERMINAL-LIKE PROTEIN macromolecule localization#GO:0033036;protein localization to cytoskeleton#GO:0044380;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000005824.3|UniProtKB=G3QSQ8 G3QSQ8 SPEF1 PTHR12509:SF16 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERM FLAGELLA AND CILIA-ASSOCIATED PROTEIN 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000009119.3|UniProtKB=A0A2I2YLG9 A0A2I2YLG9 RYR3 PTHR46399:SF9 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 3 monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ligand-gated monoatomic cation channel activity#GO:0099094;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;muscle system process#GO:0003012;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;transport#GO:0006810;muscle contraction#GO:0006936;calcium ion transport#GO:0006816;system process#GO:0003008;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501 intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;Z disc#GO:0030018;cell periphery#GO:0071944;membraneless organelle#GO:0043228;sarcolemma#GO:0042383;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;I band#GO:0031674;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;calcium channel complex#GO:0034704;myofibril#GO:0030016;supramolecular fiber#GO:0099512;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;sarcoplasmic reticulum membrane#GO:0033017;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;sarcoplasmic reticulum#GO:0016529;contractile muscle fiber#GO:0043292;transporter complex#GO:1990351;sarcomere#GO:0030017;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;cation channel complex#GO:0034703 CCKR signaling map#P06959>RYR1/2/3#P07088;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441;Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434 GORGO|Ensembl=ENSGGOG00000022263.2|UniProtKB=G3RXB2 G3RXB2 PTHR35967:SF1 UPF0450 PROTEIN C17ORF58 UPF0450 PROTEIN C17ORF58 GORGO|Ensembl=ENSGGOG00000022168.2|UniProtKB=A0A2I2ZNY5 A0A2I2ZNY5 TFPI PTHR10083:SF328 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED TISSUE FACTOR PATHWAY INHIBITOR enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 Blood coagulation#P00011>TFPI#P00417 GORGO|Ensembl=ENSGGOG00000007912.3|UniProtKB=G3R9R7 G3R9R7 PTHR37553:SF7 DUF4705 DOMAIN-CONTAINING PROTEIN DUF4705 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000001021.3|UniProtKB=A0A2I2YEI2 A0A2I2YEI2 GLIPR1L1 PTHR10334:SF220 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIPR1-LIKE PROTEIN 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015159.3|UniProtKB=G3RGP0 G3RGP0 HEPACAM PTHR44888:SF2 HEPACAM FAMILY MEMBER 2-RELATED HEPATIC AND GLIAL CELL ADHESION MOLECULE GORGO|Ensembl=ENSGGOG00000025671.2|UniProtKB=G3RQI7 G3RQI7 CAPN7 PTHR46143:SF1 CALPAIN-7 CALPAIN-7 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000007809.3|UniProtKB=G3QXS5 G3QXS5 APCDD1L PTHR31021:SF3 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN APCDD1-LIKE GORGO|Ensembl=ENSGGOG00000013555.3|UniProtKB=G3RCI9 G3RCI9 GOPC PTHR16528:SF2 GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING PROTEIN protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 biological regulation#GO:0065007;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle#GO:0030133;clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;trans-Golgi network transport vesicle#GO:0030140;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012848.3|UniProtKB=A0A2I2Y594 A0A2I2Y594 ZNF41 PTHR24381:SF405 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 585A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000027961.2|UniProtKB=G3RWH8 G3RWH8 TTC33 PTHR24343:SF306 SERINE/THREONINE KINASE 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;intracellular protein localization#GO:0008104;regulation of TORC1 signaling#GO:1903432;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;macromolecule localization#GO:0033036;cellular response to glucose starvation#GO:0042149;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;localization#GO:0051179;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;negative regulation of TORC1 signaling#GO:1904262;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of signal transduction#GO:0009968;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 GORGO|Ensembl=ENSGGOG00000023509.2|UniProtKB=G3SGV8 G3SGV8 PTHR20852:SF45 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968;Glutamine glutamate conversion#P02745>Glutamine synthase#P04483 GORGO|Ensembl=ENSGGOG00000010079.3|UniProtKB=G3R3K5 G3R3K5 USP35 PTHR24006:SF660 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 35 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000006701.3|UniProtKB=A0A2I2Z8N0 A0A2I2Z8N0 ATP6V0E1 PTHR12263:SF5 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT E 1 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 primary active transporter#PC00068;ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000002076.3|UniProtKB=G3QI44 G3QI44 LOC101127998 PTHR24302:SF6 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A43 monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000023243.3|UniProtKB=G3RU07 G3RU07 RNF212 PTHR22663:SF21 RING FINGER PROTEIN NARYA-RELATED E3 SUMO-PROTEIN LIGASE RNF212-RELATED catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787 organelle organization#GO:0006996;cellular process#GO:0009987;homologous chromosome pairing at meiosis#GO:0007129;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome segregation#GO:0007059;meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;cell cycle process#GO:0022402;reproductive process#GO:0022414;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;synaptonemal structure#GO:0099086;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000010491.3|UniProtKB=A0A2I2Z565 A0A2I2Z565 GPAA1 PTHR13304:SF0 GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN GPI-ANCHOR TRANSAMIDASE COMPONENT GPAA1 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;GPI anchored protein biosynthesis#GO:0180046;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;caspase complex#GO:0008303;peptidase complex#GO:1905368;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011106.3|UniProtKB=G3S674 G3S674 SPMIP3 PTHR31763:SF2 HYPOTHETICAL PROTEIN LOC689766 PROTEIN SPMIP3 GORGO|Ensembl=ENSGGOG00000040085.1|UniProtKB=A0A2I2Z579 A0A2I2Z579 PTHR23266:SF385 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-49 binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000013719.3|UniProtKB=G3RCZ5 G3RCZ5 EVC PTHR16795:SF13 LIMBIN/ELLIS-VAN CREVELD PROTEIN EVC COMPLEX MEMBER EVC signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;cilium#GO:0005929;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000036448.1|UniProtKB=A0A2I2YVY7 A0A2I2YVY7 LOC101154270 PTHR10715:SF7 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005367.3|UniProtKB=G3QRK1 G3QRK1 FKBP5 PTHR10516:SF26 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5 catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;catalytic activity#GO:0003824 protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000001920.3|UniProtKB=G3QHQ9 G3QHQ9 TRAK1 PTHR15751:SF11 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;GABA receptor binding#GO:0050811;signaling receptor binding#GO:0005102;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092 cellular localization#GO:0051641;microtubule-based transport#GO:0099111;animal gross anatomical part developmental process#GO:0160108;lysosomal transport#GO:0007041;protein targeting#GO:0006605;establishment of organelle localization#GO:0051656;cell differentiation#GO:0030154;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;organelle localization#GO:0051640;endosome to lysosome transport#GO:0008333;microtubule-based movement#GO:0007018;neurogenesis#GO:0022008;mitochondrion localization#GO:0051646;vesicle cytoskeletal trafficking#GO:0099518;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;vesicle localization#GO:0051648 neuron projection#GO:0043005;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;mitochondrion#GO:0005739;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006742.3|UniProtKB=G3QV32 G3QV32 S100A12 PTHR11639:SF77 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A12 protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of signaling#GO:0023051;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;defense response#GO:0006952;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;endothelial cell migration#GO:0043542;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;positive regulation of signal transduction#GO:0009967;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell motility#GO:0048870 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000037805.1|UniProtKB=A0A2I2ZPY0 A0A2I2ZPY0 PTHR10665:SF4 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS RBPJ sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;Notch signaling pathway#GO:0007219;cell communication#GO:0007154 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 GORGO|Ensembl=ENSGGOG00000022618.2|UniProtKB=G3S3D4 G3S3D4 WNT4 PTHR12027:SF101 WNT RELATED PROTEIN WNT-4 protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664 developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 GORGO|Ensembl=ENSGGOG00000022981.2|UniProtKB=G3SAI3 G3SAI3 EN2 PTHR24341:SF5 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN ENGRAILED-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 GORGO|Ensembl=ENSGGOG00000008964.3|UniProtKB=G3R0R9 G3R0R9 LRRC3B PTHR46473:SF14 GH08155P LEUCINE RICH REPEAT CONTAINING 3B transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;potassium channel regulator activity#GO:0015459;binding#GO:0005488;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;molecular function activator activity#GO:0140677;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;transmembrane transporter binding#GO:0044325;channel activity#GO:0015267;channel regulator activity#GO:0016247;potassium ion transmembrane transporter activity#GO:0015079 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 GORGO|Ensembl=ENSGGOG00000026928.2|UniProtKB=G3RYT1 G3RYT1 SCGB3A2 PTHR34829:SF2 SECRETOGLOBIN FAMILY 3A MEMBER 2 SECRETOGLOBIN FAMILY 3A MEMBER 2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000004189.3|UniProtKB=G3QNJ6 G3QNJ6 MKI67 PTHR21603:SF17 ANTIGEN KI-67-LIKE PROTEIN PROLIFERATION MARKER PROTEIN KI-67 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;molecular condensate scaffold activity#GO:0140693 chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;sexual reproduction#GO:0019953;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cell cycle#GO:0007049;reproductive process#GO:0022414;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000013620.3|UniProtKB=G3RCR1 G3RCR1 CAPS2 PTHR34524:SF3 CALCYPHOSIN CALCYPHOSIN-2 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000013158.3|UniProtKB=G3RBH9 G3RBH9 EIPR1 PTHR14205:SF15 WD-REPEAT PROTEIN EARP AND GARP COMPLEX-INTERACTING PROTEIN 1 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 GORGO|Ensembl=ENSGGOG00000043622.1|UniProtKB=A0A2I2Z2W6 A0A2I2Z2W6 PTHR19343:SF17 T CELL RECEPTOR ALPHA VARIABLE 1-2 IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000006025.3|UniProtKB=G3QT87 G3QT87 CREBBP PTHR13808:SF34 CBP/P300-RELATED CREB-BINDING PROTEIN transcription regulator activity#GO:0140110;binding#GO:0005488;acetyltransferase activity#GO:0016407;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;transcription coactivator activity#GO:0003713;N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682;protein-lysine-acetyltransferase activity#GO:0061733;nucleic acid binding#GO:0003676;acyltransferase activity#GO:0016746;histone acetyltransferase activity#GO:0004402;DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557 organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;transcription regulator complex#GO:0005667;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234 histone modifying enzyme#PC00261 Wnt signaling pathway#P00057>CBP#P01448;Huntington disease#P00029>CBP#P00777;p53 pathway#P00059>CBP#P04623;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Transcription regulation by bZIP transcription factor#P00055>CBP/P300#P01387;Gonadotropin-releasing hormone receptor pathway#P06664>CBP#P06755;Hypoxia response via HIF activation#P00030>P300#P00814;Hedgehog signaling pathway#P00025>CBP#P00691 GORGO|Ensembl=ENSGGOG00000003382.4|UniProtKB=A0A2I2ZM90 A0A2I2ZM90 RBM33 PTHR22014:SF2 RNA-BINDING PROTEIN 33 RNA-BINDING PROTEIN 33 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 GORGO|Ensembl=ENSGGOG00000041074.1|UniProtKB=A0A2I2Z1D2 A0A2I2Z1D2 INSM2 PTHR15065:SF6 INSULINOMA-ASSOCIATED 1 INSULINOMA-ASSOCIATED PROTEIN 2 sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of cell cycle process#GO:0010564;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cell cycle#GO:0051726;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000007353.3|UniProtKB=G3QWN4 G3QWN4 CREB3 PTHR45996:SF4 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383 GORGO|Ensembl=ENSGGOG00000016537.3|UniProtKB=A0A2I2ZUE7 A0A2I2ZUE7 DAPK2 PTHR24342:SF15 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000001549.3|UniProtKB=G3QGR8 G3QGR8 DIS3L PTHR23355:SF30 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000025632.2|UniProtKB=A0A2I2YRI0 A0A2I2YRI0 PTHR23413:SF8 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N RPL32 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000039904.1|UniProtKB=G3RVV2 G3RVV2 PTHR11545:SF36 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of translation#GO:0017148 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000000730.3|UniProtKB=G3QEM2 G3QEM2 PTHR22972:SF5 SERINE/THREONINE PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE PEAK1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell motility#GO:2000145 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell junction#GO:0030054 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000013164.3|UniProtKB=A0A2I2ZIE0 A0A2I2ZIE0 CABP1 PTHR45917:SF1 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 1 calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;sensory perception of light stimulus#GO:0050953;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;visual perception#GO:0007601;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;signaling#GO:0023052;system process#GO:0003008;response to external stimulus#GO:0009605;detection of stimulus#GO:0051606;cellular process#GO:0009987;response to radiation#GO:0009314;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic density#GO:0014069 GORGO|Ensembl=ENSGGOG00000007171.3|UniProtKB=G3QH22 G3QH22 GBP5 PTHR10751:SF40 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 5 molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;endopeptidase inhibitor activity#GO:0004866;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme inhibitor activity#GO:0004857;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function inhibitor activity#GO:0140678;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;GTPase activity#GO:0003924;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;defense response to other organism#GO:0098542;immune system process#GO:0002376;response to virus#GO:0009615;antiviral innate immune response#GO:0140374;defense response to virus#GO:0051607;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 G-protein#PC00020;heterotrimeric G-protein#PC00117 GORGO|Ensembl=ENSGGOG00000000350.3|UniProtKB=G3QDM1 G3QDM1 PTHR23268:SF54 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 24-1 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015669.3|UniProtKB=G3RI05 G3RI05 CIMAP1C PTHR21580:SF3 SHIPPO-1-RELATED CILIARY MICROTUBULE ASSOCIATED PROTEIN 1C cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;cellular process#GO:0009987;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;spermatid development#GO:0007286;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell differentiation#GO:0030154;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006 supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic microtubule#GO:0005881;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000026172.2|UniProtKB=G3S8S6 G3S8S6 AKR1B10 PTHR11732:SF278 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B10 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000015340.3|UniProtKB=G3RH51 G3RH51 RAN PTHR24071:SF43 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;ribosome localization#GO:0033750;organelle localization#GO:0051640;protein export from nucleus#GO:0006611;gene expression#GO:0010467;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;ribosomal large subunit export from nucleus#GO:0000055;protein import into nucleus#GO:0006606;protein transport#GO:0015031;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;ribosome biogenesis#GO:0042254 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000014053.4|UniProtKB=A0A2I2YN34 A0A2I2YN34 CCSER1 PTHR22461:SF1 SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2-RELATED SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000034859.2|UniProtKB=A0A2I2YGJ3 A0A2I2YGJ3 PTPRT PTHR19134:SF208 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE T hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;cell communication#GO:0007154;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000024679.2|UniProtKB=G3SJW8 G3SJW8 CHMP2B PTHR10476:SF72 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2B cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;late endosome to vacuole transport#GO:0045324;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012372.3|UniProtKB=G3R9J7 G3R9J7 FAM114A1 PTHR12842:SF4 FI01459P PROTEIN NOXP20 GORGO|Ensembl=ENSGGOG00000025419.2|UniProtKB=G3S0I9 G3S0I9 TDRKH PTHR22948:SF18 TUDOR DOMAIN CONTAINING PROTEIN TUDOR AND KH DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016583.3|UniProtKB=A0A2I2Z719 A0A2I2Z719 NSUN2 PTHR22808:SF20 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING RNA CYTOSINE C(5)-METHYLTRANSFERASE NSUN2 catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;tRNA wobble base modification#GO:0002097;ribonucleoprotein complex biogenesis#GO:0022613;tRNA modification#GO:0006400;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;RNA metabolic process#GO:0016070;methylation#GO:0032259;cellular process#GO:0009987;tRNA methylation#GO:0030488;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;nucleic acid metabolic process#GO:0090304;mitochondrial large ribosomal subunit assembly#GO:1902775;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;mitochondrial ribosome assembly#GO:0061668;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000009749.3|UniProtKB=G3R2R6 G3R2R6 P3H2 PTHR14049:SF1 LEPRECAN 1 PROLYL 3-HYDROXYLASE 2 catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000015632.3|UniProtKB=G3RHX1 G3RHX1 TTL PTHR46570:SF1 TUBULIN--TYROSINE LIGASE TUBULIN--TYROSINE LIGASE catalytic activity, acting on a protein#GO:0140096;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle microtubule#GO:0005876;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000012466.3|UniProtKB=G3RQ02 G3RQ02 PTHR37553:SF10 DUF4705 DOMAIN-CONTAINING PROTEIN DUF4705 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000036876.1|UniProtKB=A0A2I2ZI62 A0A2I2ZI62 PTHR46595:SF4 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025252.2|UniProtKB=A0A2I2YYC2 A0A2I2YYC2 PTHR46734:SF4 TELOMERIC REPEAT-BINDING FACTOR 1 TERF1 TELOMERIC REPEAT-BINDING FACTOR sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;catalytic activity, acting on DNA#GO:0140097;telomerase activity#GO:0003720;DNA polymerase activity#GO:0034061;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;RNA-directed DNA polymerase activity#GO:0003964;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;telomere maintenance via telomerase#GO:0007004;telomere maintenance via telomere lengthening#GO:0010833;negative regulation of chromosome organization#GO:2001251;telomere organization#GO:0032200;nucleic acid metabolic process#GO:0090304;negative regulation of organelle organization#GO:0010639;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA-templated DNA biosynthetic process#GO:0006278;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;regulation of telomere maintenance#GO:0032204;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA metabolic process#GO:0051053 nuclear telomere cap complex#GO:0000783;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000024680.2|UniProtKB=A0A2I2YNI8 A0A2I2YNI8 PTHR12847:SF14 ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED NECAP PHEAR DOMAIN-CONTAINING PROTEIN organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000012799.3|UniProtKB=A0A2I2YP03 A0A2I2YP03 LRCH3 PTHR48051:SF44 FAMILY NOT NAMED LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 3 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000038418.1|UniProtKB=A0A2I2YXJ8 A0A2I2YXJ8 PTHR11661:SF21 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11 binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011720.3|UniProtKB=G3R7T2 G3R7T2 DUOXA2 PTHR31158:SF2 DUAL OXIDASE 2 DUAL OXIDASE MATURATION FACTOR 2 cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000025103.2|UniProtKB=G3RY53 G3RY53 PTHR16260:SF5 SIMILAR TO 1700123O20RIK PROTEIN CHROMOSOME 14 C14ORF119 HOMOLOG GORGO|Ensembl=ENSGGOG00000028317.2|UniProtKB=A0A2I2YI05 A0A2I2YI05 PTHR46756:SF2 TRANSGELIN CALPONIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of microtubule-based process#GO:0032886;actin filament-based process#GO:0030029;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;supramolecular fiber organization#GO:0097435;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;protein localization to microtubule cytoskeleton#GO:0072698;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;actin filament organization#GO:0007015;intracellular protein localization#GO:0008104 microtubule cytoskeleton#GO:0015630;actomyosin#GO:0042641;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;microtubule end#GO:1990752;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule#GO:0005874;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000043250.1|UniProtKB=G3QET0 G3QET0 GABRA6 PTHR18945:SF335 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-6 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;chloride transmembrane transport#GO:1902476;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;nervous system development#GO:0007399;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;cellular process#GO:0009987;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;chloride transport#GO:0006821;signaling#GO:0023052;synapse assembly#GO:0007416;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;animal gross anatomical part developmental process#GO:0160108 cell projection membrane#GO:0031253;dendrite#GO:0030425;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;cell junction#GO:0030054;signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000024563.2|UniProtKB=G3SI52 G3SI52 PTHR11353:SF195 CHAPERONIN CCT-EPSILON metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 protein folding chaperone complex#GO:0101031;chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000005278.3|UniProtKB=G3QRC5 G3QRC5 SLC66A2 PTHR14856:SF10 PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN SOLUTE CARRIER FAMILY 66 MEMBER 2 cellular component organization#GO:0016043;lipid translocation#GO:0034204;cytosolic transport#GO:0016482;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;cytoplasmic vesicle membrane#GO:0030659 GORGO|Ensembl=ENSGGOG00000009553.3|UniProtKB=G3RRW8 G3RRW8 GAPDH PTHR10836:SF111 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nucleobase-containing compound metabolic process#GO:0006139;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 GORGO|Ensembl=ENSGGOG00000001904.3|UniProtKB=G3QHP0 G3QHP0 OAZ3 PTHR10279:SF9 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 3 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000009007.3|UniProtKB=A0A2I2Z9J0 A0A2I2Z9J0 DSTN PTHR11913:SF18 COFILIN-RELATED DESTRIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 protein depolymerization#GO:0051261;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;actin cytoskeleton organization#GO:0030036;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;cellular component organization#GO:0016043;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000006029.3|UniProtKB=G3QT90 G3QT90 CDH1 PTHR24027:SF319 CADHERIN-23 CADHERIN-1 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cell migration#GO:0016477;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;system development#GO:0048731;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;cell motility#GO:0048870;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cell junction assembly#GO:0034329;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane raft#GO:0045121;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;caveola#GO:0005901;cell-cell junction#GO:0005911;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;membrane microdomain#GO:0098857;apical junction complex#GO:0043296 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Alzheimer disease-presenilin pathway#P00004>E-cadherin C-terminal fragment#P00117;CCKR signaling map#P06959>E-cadherin#G06981;Wnt signaling pathway#P00057>Cadherin#P01440;Alzheimer disease-presenilin pathway#P00004>E-cadherin intracellular fragment#P00168;Alzheimer disease-presenilin pathway#P00004>E-cadherin#P00118;Alzheimer disease-presenilin pathway#P00004>E-cadherin N-terminal fragment#P00165;CCKR signaling map#P06959>E-cadherin#P07171;Alzheimer disease-presenilin pathway#P00004>E-cadherin transmembrane fragment#P00139;CCKR signaling map#P06959>E-cadherin#G07274 GORGO|Ensembl=ENSGGOG00000001853.3|UniProtKB=G3QHJ6 G3QHJ6 NPBWR2 PTHR24229:SF18 NEUROPEPTIDES RECEPTOR NEUROPEPTIDES B_W RECEPTOR TYPE 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000006771.3|UniProtKB=G3QV81 G3QV81 NCAPD3 PTHR14222:SF1 CONDENSIN CONDENSIN-2 COMPLEX SUBUNIT D3 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;sexual reproduction#GO:0019953;nuclear division#GO:0000280;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;condensin complex#GO:0000796 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000016343.3|UniProtKB=G3RJQ0 G3RJQ0 FBXO16 PTHR46857:SF2 EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE F-BOX ONLY PROTEIN 16 GORGO|Ensembl=ENSGGOG00000015245.3|UniProtKB=G3RGX2 G3RGX2 RERE PTHR13859:SF12 ATROPHIN-RELATED ARGININE-GLUTAMIC ACID DIPEPTIDE REPEATS PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000003810.3|UniProtKB=G3QMK3 G3QMK3 MCAM PTHR11973:SF18 CELL SURFACE GLYCOPROTEIN MUC18-RELATED CELL SURFACE GLYCOPROTEIN MUC18 animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;circulatory system development#GO:0072359;developmental process#GO:0032502;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tube development#GO:0035295 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000005429.3|UniProtKB=Q863A5 Q863A5 DNAAF4 PTHR46492:SF2 DYNEIN ASSEMBLY FACTOR 4, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 4 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;nuclear estrogen receptor binding#GO:0030331;binding#GO:0005488;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922 outer dynein arm assembly#GO:0036158;multicellular organismal process#GO:0032501;regionalization#GO:0003002;plasma membrane bounded cell projection organization#GO:0120036;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234;determination of left/right symmetry#GO:0007368;microtubule-based movement#GO:0007018;organelle assembly#GO:0070925;pattern specification process#GO:0007389;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;system development#GO:0048731;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;heart development#GO:0007507;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;determination of bilateral symmetry#GO:0009855;left/right pattern formation#GO:0060972;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;inner dynein arm assembly#GO:0036159;microtubule-based transport#GO:0099111;cilium movement#GO:0003341;cilium organization#GO:0044782 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000000956.3|UniProtKB=G3QF76 G3QF76 LEP PTHR11724:SF1 LEPTIN LEPTIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 energy derivation by oxidation of organic compounds#GO:0015980;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;lipid metabolic process#GO:0006629;regulation of response to stimulus#GO:0048583;generation of precursor metabolites and energy#GO:0006091;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;response to peptide hormone#GO:0043434;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;energy reserve metabolic process#GO:0006112;cytokine-mediated signaling pathway#GO:0019221;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000001934.3|UniProtKB=G3SDW2 G3SDW2 PTHR40250:SF1 CHROMOSOME 11 OPEN READING FRAME 96 SI:CH1073-281M9.1 GORGO|Ensembl=ENSGGOG00000001099.3|UniProtKB=G3SGN8 G3SGN8 APOBEC2 PTHR13857:SF4 MRNA EDITING ENZYME C-U-EDITING ENZYME APOBEC-2 catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity#GO:0016787;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;base conversion or substitution editing#GO:0016553;metabolic process#GO:0008152;RNA modification#GO:0009451;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cytidine to uridine editing#GO:0016554;cellular process#GO:0009987 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000037904.1|UniProtKB=A0A2I2ZIM7 A0A2I2ZIM7 UBE2V2 PTHR24068:SF177 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;cellular process#GO:0009987;response to stress#GO:0006950;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000000739.3|UniProtKB=G3QEN1 G3QEN1 OTUD1 PTHR12419:SF101 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000002706.3|UniProtKB=G3SD86 G3SD86 AATF PTHR15565:SF0 AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR PROTEIN AATF gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008428.3|UniProtKB=A0A2I2Z7L0 A0A2I2Z7L0 EXOSC5 PTHR11953:SF1 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP46 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;snRNA 3'-end processing#GO:0034472;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;snRNA metabolic process#GO:0016073;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;nuclear mRNA surveillance#GO:0071028;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000022807.2|UniProtKB=G3RS84 G3RS84 GADD45GIP1 PTHR31761:SF1 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEINS-INTERACTING PROTEIN 1 GADD45GIP1 LARGE RIBOSOMAL SUBUNIT PROTEIN ML64 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000011699.3|UniProtKB=A0A2I2Z542 A0A2I2Z542 SP3 PTHR23235:SF3 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 CCKR signaling map#P06959>SP3#P07041 GORGO|Ensembl=ENSGGOG00000004599.3|UniProtKB=G3QPL1 G3QPL1 MICU3 PTHR12294:SF10 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 3, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;metal ion transport#GO:0030001 mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;transporter complex#GO:1990351;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000041552.1|UniProtKB=A0A2I2ZVN5 A0A2I2ZVN5 PTHR26452:SF740 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012552.3|UniProtKB=G3RA00 G3RA00 ACAA2 PTHR18919:SF145 ACETYL-COA C-ACYLTRANSFERASE 3-KETOACYL-COA THIOLASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000006086.3|UniProtKB=G3S8X3 G3S8X3 MAP2K6 PTHR48013:SF12 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>MKK3,6#P00540;Ras Pathway#P04393>MKK3/6#P04568;Gonadotropin-releasing hormone receptor pathway#P06664>MKK3/6#P06805;FGF signaling pathway#P00021>MKK3,6#P00625;CCKR signaling map#P06959>MAP2K6#P07233;Oxidative stress response#P00046>MKK3/6#P01121;p38 MAPK pathway#P05918>MKK6#P06032 GORGO|Ensembl=ENSGGOG00000010449.3|UniProtKB=G3RUM1 G3RUM1 GAL3ST3 PTHR14647:SF83 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009672.3|UniProtKB=G3R2J5 G3R2J5 ACMSD PTHR21240:SF27 2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 secondary metabolic process#GO:0019748;cellular process#GO:0009987;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 GORGO|Ensembl=ENSGGOG00000042114.1|UniProtKB=A0A2I2ZMJ8 A0A2I2ZMJ8 PTHR19336:SF12 UNCHARACTERIZED DUF1167 CENTROSOMAL PROTEIN CEP57L1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;microtubule binding#GO:0008017;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;organelle organization#GO:0006996;attachment of spindle microtubules to kinetochore#GO:0008608;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226 organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000016812.3|UniProtKB=G3RUU8 G3RUU8 PTHR33769:SF1 TESTIS-EXPRESSED PROTEIN 26 ISOFORM X3 TESTIS-EXPRESSED PROTEIN 26 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000025510.2|UniProtKB=G3RN71 G3RN71 KIFAP3 PTHR15605:SF2 KINESIN-ASSOCIATED PROTEINS KINESIN-ASSOCIATED PROTEIN 3 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium organization#GO:0044782;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary transition zone#GO:0035869;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000000506.3|UniProtKB=G3QE15 G3QE15 KDM4C PTHR10694:SF104 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4C oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;protein demethylase activity#GO:0140457;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000008015.3|UniProtKB=G3QYA7 G3QYA7 TAB1 PTHR13832:SF533 PROTEIN PHOSPHATASE 2C TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 protein phosphatase#PC00195 p38 MAPK pathway#P05918>TAB1#P06035;Toll receptor signaling pathway#P00054>TAB1#P01365;TGF-beta signaling pathway#P00052>TAB#P01290 GORGO|Ensembl=ENSGGOG00000007419.3|UniProtKB=G3QWU0 G3QWU0 CEBPE PTHR23334:SF27 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN EPSILON sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;myeloid cell differentiation#GO:0030099;regulation of cellular process#GO:0050794;cell development#GO:0048468;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;hemopoiesis#GO:0030097 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000014839.3|UniProtKB=G3RZ59 G3RZ59 C16H15orf39 PTHR28422:SF1 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 39 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 39 regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical NF-kappaB signal transduction#GO:0043122;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000182.4|UniProtKB=G3QD69 G3QD69 CDH4 PTHR24027:SF81 CADHERIN-23 CADHERIN-4 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell motility#GO:0048870;cell migration#GO:0016477;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000012527.3|UniProtKB=G3R9Y5 G3R9Y5 SCN4A PTHR10037:SF223 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 4 SUBUNIT ALPHA passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transport#GO:0006810;system process#GO:0003008;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;action potential#GO:0001508;sensory perception of pain#GO:0019233;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;nervous system process#GO:0050877;sensory perception#GO:0007600;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;axon#GO:0030424;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;transporter complex#GO:1990351;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000015242.3|UniProtKB=G3RGW1 G3RGW1 MORN4 PTHR46614:SF1 MORN REPEAT-CONTAINING PROTEIN 4 MORN REPEAT-CONTAINING PROTEIN 4 response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950 cell projection#GO:0042995;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000540.3|UniProtKB=G3QE44 G3QE44 TMEM53 PTHR12265:SF30 TRANSMEMBRANE PROTEIN 53 TRANSMEMBRANE PROTEIN 53 GORGO|Ensembl=ENSGGOG00000036464.1|UniProtKB=A0A2I2YI20 A0A2I2YI20 IL37 PTHR10078:SF31 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-37 cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;defense response#GO:0006952;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;inflammatory response#GO:0006954;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000036892.1|UniProtKB=A0A2I2Z296 A0A2I2Z296 LOC101136640 PTHR24377:SF771 IP01015P-RELATED ZINC FINGER PROTEIN 284 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011884.3|UniProtKB=G3R8A0 G3R8A0 PLEKHG6 PTHR47671:SF1 PLECKSTRIN DOMAIN-CONTAINING FAMILY G MEMBER 6 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 6 GORGO|Ensembl=ENSGGOG00000016805.3|UniProtKB=G3RTF6 G3RTF6 DMXL1 PTHR13950:SF12 RABCONNECTIN-RELATED DMX-LIKE PROTEIN 1 vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular localization#GO:0051641;localization#GO:0051179 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000015205.3|UniProtKB=G3RGS6 G3RGS6 CBLN1 PTHR22923:SF5 CEREBELLIN-RELATED CEREBELLIN-1 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001105.3|UniProtKB=G3QFL2 G3QFL2 HOXC10 PTHR45874:SF2 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-C10 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000009435.3|UniProtKB=G3R1Y0 G3R1Y0 FOSL2 PTHR23351:SF25 FOS TRANSCRIPTION FACTOR-RELATED FOS-RELATED ANTIGEN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000041837.1|UniProtKB=A0A2I2ZAU2 A0A2I2ZAU2 TIFAB PTHR31266:SF3 TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A FAMILY MEMBER TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN B molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134;enzyme activator activity#GO:0008047 regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;toll-like receptor signaling pathway#GO:0002224;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764 GORGO|Ensembl=ENSGGOG00000034986.2|UniProtKB=A0A2I2ZIU3 A0A2I2ZIU3 POLR2B PTHR20856:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000022481.2|UniProtKB=G3S558 G3S558 TMEM161A PTHR13624:SF4 RE42071P TRANSMEMBRANE PROTEIN 161A GORGO|Ensembl=ENSGGOG00000008140.3|UniProtKB=G3QYM6 G3QYM6 DLG5 PTHR46360:SF1 DISKS LARGE HOMOLOG 5 DISKS LARGE HOMOLOG 5 negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000017080.3|UniProtKB=G3RLL4 G3RLL4 MYPOP PTHR32345:SF3 MYB-RELATED TRANSCRIPTION FACTOR, PARTNER OF PROFILIN MYB-RELATED TRANSCRIPTION FACTOR, PARTNER OF PROFILIN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000011641.3|UniProtKB=G3SAU7 G3SAU7 LHFPL6 PTHR12489:SF12 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 6 PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015212.3|UniProtKB=G3RQS0 G3RQS0 ATP8B4 PTHR24092:SF80 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IM-RELATED intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215 lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;Golgi organization#GO:0007030;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid transport#GO:0015914;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013744.3|UniProtKB=G3RNX9 G3RNX9 PGPEP1 PTHR23402:SF16 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED PYROGLUTAMYL-PEPTIDASE 1 peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000012729.3|UniProtKB=G3RAE8 G3RAE8 PEX14 PTHR23058:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX14 PEROXISOMAL MEMBRANE PROTEIN PEX14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;peroxisome organization#GO:0007031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;peroxisomal transport#GO:0043574 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;transporter complex#GO:1990351;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peroxisomal membrane#GO:0005778;organelle#GO:0043226 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025682.2|UniProtKB=G3S8M0 G3S8M0 CCL21 PTHR12015:SF72 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 21 chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;regulation of cell motility#GO:2000145;cell chemotaxis#GO:0060326;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to peptide#GO:1901652;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cellular process#GO:0009987;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;response to chemical#GO:0042221;response to cytokine#GO:0034097;taxis#GO:0042330;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000027287.2|UniProtKB=G3RWS6 G3RWS6 FBXO46 PTHR16271:SF10 F-BOX ONLY PROTEIN 34/46 FAMILY MEMBER F-BOX ONLY PROTEIN 46 GORGO|Ensembl=ENSGGOG00000013462.3|UniProtKB=G3RCA8 G3RCA8 PTHR24366:SF134 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS CHONDROADHERIN-LIKE PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000023046.2|UniProtKB=G3S423 G3S423 PTHR10351:SF29 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 HOMOLOG 4 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013591.3|UniProtKB=G3RCM0 G3RCM0 GLIPR1 PTHR10334:SF459 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIOMA PATHOGENESIS-RELATED PROTEIN 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000023267.2|UniProtKB=G3S0H2 G3S0H2 REXO2 PTHR11046:SF0 OLIGORIBONUCLEASE, MITOCHONDRIAL OLIGORIBONUCLEASE, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000043968.1|UniProtKB=A0A2I2YZ13 A0A2I2YZ13 GPR4 PTHR24234:SF10 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000009481.3|UniProtKB=A0A2I2ZP05 A0A2I2ZP05 RECQL5 PTHR13710:SF152 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q5 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694 DNA helicase#PC00011;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000010988.3|UniProtKB=A0A2I2Y9T6 A0A2I2Y9T6 LOC101142148 PTHR46514:SF2 AMPHIPHYSIN AMPHIPHYSIN phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 synaptic vesicle endocytosis#GO:0048488;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234 endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000036291.1|UniProtKB=G3RNC3 G3RNC3 PTHR23267:SF413 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 1-44-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000803.3|UniProtKB=G3QEU0 G3QEU0 SLC29A3 PTHR10332:SF17 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 3 nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337;carbohydrate derivative transmembrane transporter activity#GO:1901505;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002514.3|UniProtKB=G3QJ91 G3QJ91 C4H17orf75 PTHR14416:SF2 PROTEIN NJMU-R1 PROTEIN NJMU-R1 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007011.3|UniProtKB=G3RT61 G3RT61 HOMER3 PTHR10918:SF4 HOMER HOMER PROTEIN HOMOLOG 3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;regulation of monoatomic ion transport#GO:0043269;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cell surface receptor signaling pathway#GO:0007166 intracellular anatomical structure#GO:0005622;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;cell junction#GO:0030054;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000015418.3|UniProtKB=A0A2I2YZG7 A0A2I2YZG7 DDX5 PTHR47958:SF90 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX5-RELATED catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000015539.3|UniProtKB=G3RHN2 G3RHN2 ZSCAN1 PTHR23226:SF332 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008845.3|UniProtKB=G3SFG8 G3SFG8 BST1 PTHR10912:SF4 ADP-RIBOSYL CYCLASE ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;cyclase#PC00079 GORGO|Ensembl=ENSGGOG00000003140.3|UniProtKB=G3QKV5 G3QKV5 SLC6A5 PTHR11616:SF241 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 2 carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;glycine transmembrane transporter activity#GO:0015187;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 glycine transport#GO:0015816;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;carboxylic acid transmembrane transport#GO:1905039;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;import across plasma membrane#GO:0098739;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic cation transmembrane transport#GO:0098655 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000001445.3|UniProtKB=G3QGG9 G3QGG9 EEFSEC PTHR43721:SF11 ELONGATION FACTOR TU-RELATED SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 regulation of macromolecule metabolic process#GO:0060255;protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;translation#GO:0006412;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;translational elongation#GO:0006414;post-transcriptional regulation of gene expression#GO:0010608 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000039574.1|UniProtKB=A0A2I2YVV0 A0A2I2YVV0 LRATD1 PTHR46341:SF1 PROTEIN FAM84B-RELATED PROTEIN LRATD1 developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;anatomical structure development#GO:0048856;cell motility#GO:0048870;cell morphogenesis#GO:0000902 GORGO|Ensembl=ENSGGOG00000007894.3|UniProtKB=G3QY01 G3QY01 ARPC5 PTHR12644:SF1 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 GORGO|Ensembl=ENSGGOG00000022165.2|UniProtKB=G3S076 G3S076 CKS2 PTHR23415:SF48 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 2 kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle phase transition#GO:0044772;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012185.3|UniProtKB=G3R911 G3R911 DDIAS PTHR35537:SF1 DNA DAMAGE-INDUCIBLE APOPTOSIS SUPPRESSOR PROTEIN DDIAS DNA DAMAGE-INDUCED APOPTOSIS SUPPRESSOR PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000001375.3|UniProtKB=G3QGA5 G3QGA5 CALHM6 PTHR32261:SF4 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 6 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000014279.3|UniProtKB=G3REE3 G3REE3 SLC25A5 PTHR45635:SF3 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 2 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000006446.3|UniProtKB=G3QUB0 G3QUB0 SCN10A PTHR10037:SF208 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 10 SUBUNIT ALPHA passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 regulation of biological process#GO:0050789;action potential#GO:0001508;sodium ion transport#GO:0006814;sensory perception of pain#GO:0019233;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;regulation of heart contraction#GO:0008016;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;nervous system process#GO:0050877;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;transport#GO:0006810;regulation of system process#GO:0044057;system process#GO:0003008;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000036228.1|UniProtKB=A0A2I2ZPU2 A0A2I2ZPU2 ARL14 PTHR11711:SF29 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 14 GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000014845.3|UniProtKB=A0A2I2YPI9 A0A2I2YPI9 GRIA1 PTHR18966:SF157 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1 carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023 regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536 somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;signaling receptor complex#GO:0043235;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;dendrite#GO:0030425;protein-containing complex#GO:0032991;neuron projection#GO:0043005;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;neuron spine#GO:0044309;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;dendritic spine#GO:0043197;postsynapse#GO:0098794;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 GORGO|Ensembl=ENSGGOG00000008798.3|UniProtKB=G3R0B5 G3R0B5 BCHE PTHR43918:SF5 ACETYLCHOLINESTERASE CHOLINESTERASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 GORGO|Ensembl=ENSGGOG00000004892.3|UniProtKB=A0A2I2ZMV3 A0A2I2ZMV3 SLC6A13 PTHR11616:SF111 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 2 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943 cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;amino acid transport#GO:0006865;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000010847.3|UniProtKB=A0A2I2YYP5 A0A2I2YYP5 DHTKD1 PTHR23152:SF38 2-OXOGLUTARATE DEHYDROGENASE 2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000004504.3|UniProtKB=G3QPC3 G3QPC3 CCL8 PTHR12015:SF209 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 8 cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell chemotaxis#GO:0060326;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell motility#GO:2000145;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cytokine-mediated signaling pathway#GO:0019221;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;biological regulation#GO:0065007;cell migration#GO:0016477;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;response to peptide#GO:1901652;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;cell surface receptor signaling pathway#GO:0007166;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;taxis#GO:0042330;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000001355.3|UniProtKB=G3QG89 G3QG89 PIK3C2B PTHR10048:SF30 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT BETA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;cell motility#GO:0048870;phosphatidylinositol phosphate biosynthetic process#GO:0046854;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;biosynthetic process#GO:0009058;intracellular signaling cassette#GO:0141124;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137 Angiogenesis#P00005>PI3K#P00236;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;EGF receptor signaling pathway#P00018>PI3K#P00557;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;p53 pathway feedback loops 2#P04398>PI3K#P04661;FGF signaling pathway#P00021>PI3K#P00640;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363 GORGO|Ensembl=ENSGGOG00000027873.2|UniProtKB=G3SGI4 G3SGI4 SAT1 PTHR10545:SF36 DIAMINE N-ACETYLTRANSFERASE DIAMINE ACETYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;cation binding#GO:0043169;small molecule binding#GO:0036094;acetyltransferase activity#GO:0016407;binding#GO:0005488;ion binding#GO:0043167;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 acetyltransferase#PC00038;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000011696.3|UniProtKB=G3R7T1 G3R7T1 FANCI PTHR21818:SF0 BC025462 PROTEIN FANCONI ANEMIA GROUP I PROTEIN regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;DNA damage response#GO:0006974;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA repair complex#GO:1990391;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013008.3|UniProtKB=G3RB54 G3RB54 DELE1 PTHR45011:SF1 DAP3-BINDING CELL DEATH ENHANCER 1 DAP3-BINDING CELL DEATH ENHANCER 1 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stress#GO:0033554;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003937.3|UniProtKB=G3QMW5 G3QMW5 SNRPB2 PTHR10501:SF84 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B'' snRNA binding#GO:0017069;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 mRNA splicing#P00058>U2#P01478 GORGO|Ensembl=ENSGGOG00000004784.3|UniProtKB=G3RRM2 G3RRM2 RTEL1 PTHR11472:SF62 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER REGULATOR OF TELOMERE ELONGATION HELICASE 1 protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;enzyme binding#GO:0019899;ATP-dependent activity#GO:0140657;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleic acid conformation isomerase activity#GO:0120545;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;isomerase activity#GO:0016853;nucleotide binding#GO:0000166;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 organelle organization#GO:0006996;cellular process#GO:0009987;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;regulation of cellular component biogenesis#GO:0044087;regulation of DNA recombination#GO:0000018;regulation of cellular response to stress#GO:0080135;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA metabolic process#GO:0051053;regulation of response to stress#GO:0080134;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;macromolecule metabolic process#GO:0043170;regulation of telomere maintenance#GO:0032204;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;negative regulation of DNA recombination#GO:0045910;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;telomere organization#GO:0032200;regulation of double-strand break repair#GO:2000779 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000028195.2|UniProtKB=G3SDL1 G3SDL1 PTHR12845:SF2 GUANINE NUCLEOTIDE EXCHANGE FACTOR DH DOMAIN-CONTAINING PROTEIN-RELATED guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of actin filament-based process#GO:0032970;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000022689.2|UniProtKB=A0A2I2ZK91 A0A2I2ZK91 PTHR20988:SF2 TRANSMEMBRANE PROTEIN 183A-RELATED TRANSMEMBRANE PROTEIN 183A-RELATED ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000024621.2|UniProtKB=G3SEL0 G3SEL0 PTHR16922:SF0 INTERLEUKIN 11 INTERLEUKIN-11 growth factor activity#GO:0008083;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cell population proliferation#GO:0042127;positive regulation of signaling#GO:0023056;positive regulation of cell population proliferation#GO:0008284;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cytokine#PC00083;interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970 GORGO|Ensembl=ENSGGOG00000010961.3|UniProtKB=A0A2I2ZJZ4 A0A2I2ZJZ4 SOCS7 PTHR10155:SF5 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 7 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular response to chemical stimulus#GO:0070887;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to peptide hormone#GO:0043434 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 GORGO|Ensembl=ENSGGOG00000023042.2|UniProtKB=G3RVF4 G3RVF4 LOC101153430 PTHR11588:SF429 TUBULIN TUBULIN BETA 8B-RELATED guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 GORGO|Ensembl=ENSGGOG00000042612.1|UniProtKB=A0A2I2Z817 A0A2I2Z817 SNX20 PTHR20939:SF1 SORTING NEXIN 20, 21 SORTING NEXIN-20 phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022677.2|UniProtKB=G3S4K8 G3S4K8 PTHR13937:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152 eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000025776.2|UniProtKB=G3S9Z8 G3S9Z8 PTHR11843:SF30 40S RIBOSOMAL PROTEIN S12 40S RIBOSOMAL PROTEIN S12 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex biogenesis#GO:0022613;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;cellular component biogenesis#GO:0044085;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;translation#GO:0006412;ribosomal small subunit biogenesis#GO:0042274;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000027356.2|UniProtKB=G3RNM6 G3RNM6 PTHR23226:SF306 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024554.2|UniProtKB=G3S0R2 G3S0R2 SLC25A36 PTHR45829:SF2 MITOCHONDRIAL CARRIER PROTEIN RIM2 SOLUTE CARRIER FAMILY 25 MEMBER 36 organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 GORGO|Ensembl=ENSGGOG00000016649.3|UniProtKB=A0A2I2YFY4 A0A2I2YFY4 HEATR6 PTHR13366:SF0 MALARIA ANTIGEN-RELATED HEAT REPEAT-CONTAINING PROTEIN 6 GORGO|Ensembl=ENSGGOG00000009677.3|UniProtKB=G3R2K3 G3R2K3 RPE65 PTHR10543:SF57 BETA-CAROTENE DIOXYGENASE RETINOID ISOMEROHYDROLASE oxidoreductase activity#GO:0016491;isomerase activity#GO:0016853;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;dioxygenase activity#GO:0051213;cis-trans isomerase activity#GO:0016859;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;carboxylic ester hydrolase activity#GO:0052689 isoprenoid metabolic process#GO:0006720;olefinic compound metabolic process#GO:0120254;isoprenoid biosynthetic process#GO:0008299;terpenoid metabolic process#GO:0006721;catabolic process#GO:0009056;carotenoid biosynthetic process#GO:0016117;primary metabolic process#GO:0044238;carotenoid metabolic process#GO:0016116;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;pigment biosynthetic process#GO:0046148;terpenoid biosynthetic process#GO:0016114;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;pigment metabolic process#GO:0042440;xanthophyll biosynthetic process#GO:0016123;cellular process#GO:0009987;tetraterpenoid biosynthetic process#GO:0016109;aldehyde metabolic process#GO:0006081;lipid catabolic process#GO:0016042 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000015545.3|UniProtKB=G3RHN9 G3RHN9 AK6 PTHR12595:SF19 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;nucleobase-containing compound kinase activity#GO:0019205;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;kinase activity#GO:0016301;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000012094.3|UniProtKB=G3RX81 G3RX81 LETMD1 PTHR14009:SF13 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN 1 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000036962.1|UniProtKB=A0A2I2Y8Q4 A0A2I2Y8Q4 PTHR23267:SF539 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-9-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000027314.2|UniProtKB=G3RNV7 G3RNV7 LOC101145441 PTHR23426:SF58 FERREDOXIN/ADRENODOXIN 2FE-2S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152;electron transport chain#GO:0022900 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000015417.3|UniProtKB=G3RHC4 G3RHC4 PTHR11375:SF1 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;cellular process#GO:0009987;regulation of biological process#GO:0050789;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;nuclear transport#GO:0051169;intracellular transport#GO:0046907;transport#GO:0006810;nucleocytoplasmic transport#GO:0006913;regulation of apoptotic process#GO:0042981 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000023865.2|UniProtKB=G3RZK3 G3RZK3 IDNK PTHR43442:SF3 GLUCONOKINASE-RELATED GLUCONOKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;pentose-phosphate shunt#GO:0006098;oxoacid metabolic process#GO:0043436;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000028507.2|UniProtKB=A0A2I2Y8T9 A0A2I2Y8T9 PTHR24136:SF36 SOWAH (DROSOPHILA) HOMOLOG SUBFAMILY NOT NAMED regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;positive regulation of protein metabolic process#GO:0051247;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000012670.3|UniProtKB=G3RA97 G3RA97 PABPN1L PTHR23236:SF27 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EMBRYONIC POLYADENYLATE-BINDING PROTEIN 2 RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;poly(A) binding#GO:0008143;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000009504.3|UniProtKB=G3R248 G3R248 RHBDL2 PTHR45840:SF6 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 2 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 GORGO|Ensembl=ENSGGOG00000008180.3|UniProtKB=G3QYQ5 G3QYQ5 DRGX PTHR24329:SF542 HOMEOBOX PROTEIN ARISTALESS DORSAL ROOT GANGLIA HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000003198.3|UniProtKB=G3QL05 G3QL05 AP4S1 PTHR11753:SF4 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-4 COMPLEX SUBUNIT SIGMA-1 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000040790.1|UniProtKB=A0A2I2ZIZ9 A0A2I2ZIZ9 PTHR46292:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 102A COILED-COIL DOMAIN-CONTAINING PROTEIN 102B GORGO|Ensembl=ENSGGOG00000002495.3|UniProtKB=G3S4S3 G3S4S3 SARS2 PTHR11778:SF23 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;translation#GO:0006412;mitochondrial RNA metabolic process#GO:0000959;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000043885.1|UniProtKB=A0A2I2YE20 A0A2I2YE20 FAM217B PTHR22145:SF3 SI:CH211-266K22.6 PROTEIN FAM217B GORGO|Ensembl=ENSGGOG00000015801.3|UniProtKB=G3RIB5 G3RIB5 SNAP23 PTHR19305:SF4 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 23 binding#GO:0005488;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;vesicle fusion to plasma membrane#GO:0099500;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;export from cell#GO:0140352;signaling#GO:0023052;cellular localization#GO:0051641;secretion by cell#GO:0032940;membrane fusion#GO:0061025;synaptic vesicle membrane organization#GO:0048499;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903 intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 membrane traffic protein#PC00150;SNARE protein#PC00034 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423 GORGO|Ensembl=ENSGGOG00000024448.2|UniProtKB=A0A2I2YE72 A0A2I2YE72 HECW1 PTHR11254:SF79 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HECW1 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;regulation of developmental process#GO:0050793;regulation of dendrite morphogenesis#GO:0048814;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule metabolic process#GO:0043170;regulation of plasma membrane bounded cell projection organization#GO:0120035;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;regulation of cell projection organization#GO:0031344;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000024575.2|UniProtKB=A0A2I2YBA1 A0A2I2YBA1 PTHR12416:SF6 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN FCF1 HOMOLOG maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472 intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000008226.3|UniProtKB=A0A2I2ZY58 A0A2I2ZY58 RAPGEF1 PTHR23113:SF224 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;Ras protein signal transduction#GO:0007265;positive regulation of neuron projection development#GO:0010976 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 Integrin signalling pathway#P00034>C3G#P00929 GORGO|Ensembl=ENSGGOG00000014192.3|UniProtKB=G3RE72 G3RE72 KLHL3 PTHR24412:SF179 KELCH PROTEIN KELCH-LIKE PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metal ion transport#GO:0030001;homeostatic process#GO:0042592;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;sodium ion transport#GO:0006814;primary metabolic process#GO:0044238;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;proteasomal protein catabolic process#GO:0010498;multicellular organismal process#GO:0032501;cellular process#GO:0009987;renal system process#GO:0003014;monoatomic ion homeostasis#GO:0050801;system process#GO:0003008;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;renal absorption#GO:0070293;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cytosol#GO:0005829;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002297.3|UniProtKB=G3QIQ2 G3QIQ2 STAB2 PTHR24038:SF0 STABILIN STABILIN-2 low-density lipoprotein particle receptor activity#GO:0005041;cargo receptor activity#GO:0038024;protein-containing complex binding#GO:0044877;binding#GO:0005488;lipoprotein particle binding#GO:0071813;protein-lipid complex binding#GO:0071814;low-density lipoprotein particle binding#GO:0030169 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000004405.3|UniProtKB=A0A2I2YKE0 A0A2I2YKE0 STK32A PTHR24356:SF143 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 32A catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000001685.3|UniProtKB=G3QH44 G3QH44 ACAP1 PTHR23180:SF197 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000042696.1|UniProtKB=G3R8D8 G3R8D8 LOC101137052 PTHR26453:SF692 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014632.3|UniProtKB=G3RFA8 G3RFA8 LYPD1 PTHR10036:SF7 CD59 GLYCOPROTEIN LY6_PLAUR DOMAIN-CONTAINING PROTEIN 1 acetylcholine receptor inhibitor activity#GO:0030550;signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548;signaling receptor inhibitor activity#GO:0030547;molecular function regulator activity#GO:0098772;neurotransmitter receptor regulator activity#GO:0099602;molecular function inhibitor activity#GO:0140678 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;response to chemical#GO:0042221 GORGO|Ensembl=ENSGGOG00000034915.2|UniProtKB=G3SKE7 G3SKE7 GABRB1 PTHR18945:SF429 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-1 transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;molecular transducer activity#GO:0060089;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987 synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000002483.3|UniProtKB=G3QJ61 G3QJ61 HEPACAM2 PTHR44888:SF1 HEPACAM FAMILY MEMBER 2-RELATED HEPACAM FAMILY MEMBER 2 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cellular process#GO:0009987;cytoskeleton organization#GO:0007010 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;Golgi apparatus#GO:0005794;centrosome#GO:0005813;spindle#GO:0005819;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;midbody#GO:0030496;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000038526.1|UniProtKB=A0A2I2ZG53 A0A2I2ZG53 PTHR23073:SF12 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 8 macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000000087.3|UniProtKB=G3QCY4 G3QCY4 PSKH2 PTHR24347:SF255 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H2 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000007319.3|UniProtKB=G3QWJ8 G3QWJ8 PTHR43677:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005759.3|UniProtKB=G3QSJ6 G3QSJ6 PTHR47977:SF72 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-44 ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000016270.3|UniProtKB=G3RJH8 G3RJH8 PROKR1 PTHR24241:SF137 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PROKINETICIN RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;rhythmic process#GO:0048511;cell communication#GO:0007154;circadian rhythm#GO:0007623 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000037250.1|UniProtKB=A0A2I2ZMT7 A0A2I2ZMT7 PTHR23267:SF529 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000025667.2|UniProtKB=G3SJ51 G3SJ51 SERPINB2 PTHR11461:SF61 SERINE PROTEASE INHIBITOR, SERPIN PLASMINOGEN ACTIVATOR INHIBITOR 2 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Plasminogen activating cascade#P00050>PAI-2#P01244;CCKR signaling map#P06959>PAI2#G06977;CCKR signaling map#P06959>PAI2#G07270;Blood coagulation#P00011>PAI-2#P00409 GORGO|Ensembl=ENSGGOG00000012167.3|UniProtKB=G3R8Z3 G3R8Z3 USP27X PTHR24006:SF721 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000002724.3|UniProtKB=A0A2I2ZNI6 A0A2I2ZNI6 RABEP1 PTHR31179:SF5 RAB GTPASE-BINDING EFFECTOR PROTEIN RAB GTPASE-BINDING EFFECTOR PROTEIN 1 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport to the plasma membrane#GO:0098876;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;cellular process#GO:0009987 intracellular organelle#GO:0043229;endosome#GO:0005768;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000014091.3|UniProtKB=A0A2I2ZIT3 A0A2I2ZIT3 TAC1 PTHR11250:SF3 TACHYKININ PROTACHYKININ-1 binding#GO:0005488;signaling receptor binding#GO:0005102;neuropeptide receptor binding#GO:0071855;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 regulation of biological quality#GO:0065008;defense response#GO:0006952;cell communication#GO:0007154;inflammatory response#GO:0006954;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;response to stress#GO:0006950 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 CCKR signaling map#P06959>TAC1#G07000;CCKR signaling map#P06959>TAC1#G07294 GORGO|Ensembl=ENSGGOG00000011846.3|UniProtKB=G3R857 G3R857 DUSP15 PTHR45948:SF4 DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED DUAL SPECIFICITY PROTEIN PHOSPHATASE 15 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000005392.3|UniProtKB=G3QRL9 G3QRL9 MAGEB1 PTHR11736:SF168 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B1 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016901.3|UniProtKB=G3RL54 G3RL54 KRT19 PTHR23239:SF14 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 19 structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;organelle organization#GO:0006996;cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000028432.2|UniProtKB=G3SG85 G3SG85 PTHR12801:SF124 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 4 hydrolase activity, acting on ester bonds#GO:0016788;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound catabolic process#GO:0034655;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA catabolic process#GO:0006308 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000025774.2|UniProtKB=G3SEQ1 G3SEQ1 THSD1 PTHR16311:SF3 THROMBOSPONDIN TYPE I DOMAIN-CONTAINING 1 THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 1 cell periphery#GO:0071944;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001716.3|UniProtKB=A0A2I2YE75 A0A2I2YE75 SAMD12 PTHR20843:SF2 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 12 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000007479.3|UniProtKB=G3QWZ2 G3QWZ2 TAC4 PTHR11250:SF2 TACHYKININ TACHYKININ-4 signaling receptor binding#GO:0005102;binding#GO:0005488;neuropeptide receptor binding#GO:0071855;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;inflammatory response#GO:0006954;cell communication#GO:0007154;regulation of biological quality#GO:0065008;defense response#GO:0006952;response to stress#GO:0006950;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000002395.3|UniProtKB=G3QIY8 G3QIY8 CNTN3 PTHR13817:SF84 TITIN CONTACTIN-3 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000010726.3|UniProtKB=G3R594 G3R594 NRF1 PTHR20338:SF8 NUCLEAR RESPIRATORY FACTOR 1 NUCLEAR RESPIRATORY FACTOR 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008455.3|UniProtKB=G3QZF6 G3QZF6 ERGIC1 PTHR10984:SF36 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 1 transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000005803.3|UniProtKB=G3QSP5 G3QSP5 SLC25A13 PTHR45678:SF12 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED ELECTROGENIC ASPARTATE_GLUTAMATE ANTIPORTER SLC25A13, MITOCHONDRIAL amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;C4-dicarboxylate transmembrane transporter activity#GO:0015556;carboxylic acid transmembrane transporter activity#GO:0046943 nucleoside phosphate metabolic process#GO:0006753;carboxylic acid transmembrane transport#GO:1905039;primary metabolic process#GO:0044238;L-alpha-amino acid transmembrane transport#GO:1902475;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;L-glutamate import#GO:0051938;pyridine-containing compound metabolic process#GO:0072524;dicarboxylic acid transport#GO:0006835;nucleobase-containing compound metabolic process#GO:0006139;nitrogen compound transport#GO:0071705;NAD+ metabolic process#GO:0019674;L-amino acid transport#GO:0015807;organophosphate metabolic process#GO:0019637;aspartate transmembrane transport#GO:0015810;establishment of localization#GO:0051234;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;transmembrane transport#GO:0055085;nucleotide metabolic process#GO:0009117;L-glutamate transmembrane transport#GO:0015813;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000002083.3|UniProtKB=G3QI51 G3QI51 UCKL1 PTHR10285:SF68 URIDINE KINASE URIDINE-CYTIDINE KINASE-LIKE 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150 GORGO|Ensembl=ENSGGOG00000042220.1|UniProtKB=A0A2I2Y5Y8 A0A2I2Y5Y8 PTHR12345:SF22 SYNTENIN RELATED PDZ DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of response to stimulus#GO:0048583;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013817.3|UniProtKB=G3RD81 G3RD81 R3HCC1 PTHR21678:SF6 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 R3H AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000024186.2|UniProtKB=A0A2I2ZLZ4 A0A2I2ZLZ4 PTHR23266:SF113 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000042847.1|UniProtKB=A0A2I2YC85 A0A2I2YC85 PTHR18860:SF67 14-3-3 PROTEIN 14-3-3 PROTEIN EPSILON protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624;Parkinson disease#P00049>14-3-3#P01238 GORGO|Ensembl=ENSGGOG00000007817.3|UniProtKB=G3QXT3 G3QXT3 NRIP3 PTHR12917:SF16 ASPARTYL PROTEASE DDI-RELATED NUCLEAR RECEPTOR-INTERACTING PROTEIN 3 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 aspartic protease#PC00053;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007807.3|UniProtKB=G3QXT7 G3QXT7 PLCE1 PTHR10336:SF6 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE EPSILON-1 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;transport#GO:0006810;establishment of localization#GO:0051234;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;monoatomic ion transmembrane transport#GO:0034220;Ras protein signal transduction#GO:0007265;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;signal transduction#GO:0007165;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;monoatomic cation transmembrane transport#GO:0098655;intracellular signaling cassette#GO:0141124;G protein-coupled receptor signaling pathway#GO:0007186;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052 hydrolase#PC00121;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143 Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 GORGO|Ensembl=ENSGGOG00000003831.3|UniProtKB=G3QML9 G3QML9 MYD88 PTHR15079:SF12 MYD88 MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 response to other organism#GO:0051707;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;toll-like receptor 4 signaling pathway#GO:0034142;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;activation of innate immune response#GO:0002218;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;defense response to Gram-positive bacterium#GO:0050830;regulation of biological process#GO:0050789;defense response to bacterium#GO:0042742;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>MyD88#P01377 GORGO|Ensembl=ENSGGOG00000013705.3|UniProtKB=G3SIS4 G3SIS4 EVC2 PTHR16795:SF14 LIMBIN/ELLIS-VAN CREVELD PROTEIN LIMBIN regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224 membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;cilium#GO:0005929;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000011097.3|UniProtKB=G3R682 G3R682 NUGGC PTHR47308:SF1 NUCLEAR GTPASE SLIP-GC NUCLEAR GTPASE SLIP-GC hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 GORGO|Ensembl=ENSGGOG00000007020.3|UniProtKB=G3QVT4 G3QVT4 TTC34 PTHR44874:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 34 TETRATRICOPEPTIDE REPEAT PROTEIN 34 GORGO|Ensembl=ENSGGOG00000041767.1|UniProtKB=A0A2I2YPV5 A0A2I2YPV5 C22H21orf58 PTHR28604:SF2 FAMILY NOT NAMED RIKEN CDNA 2610028H24 GENE GORGO|Ensembl=ENSGGOG00000011967.3|UniProtKB=G3R8F9 G3R8F9 HINT1 PTHR23089:SF45 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 nucleotide phosphatase#PC00173 GORGO|Ensembl=ENSGGOG00000009128.3|UniProtKB=G3R167 G3R167 FRRS1L PTHR46902:SF1 DOMON DOMAIN-CONTAINING PROTEIN FRRS1L DOMON DOMAIN-CONTAINING PROTEIN FRRS1L regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological quality#GO:0065008 GORGO|Ensembl=ENSGGOG00000008842.3|UniProtKB=G3R0G2 G3R0G2 NXPE4 PTHR16165:SF27 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 4 GORGO|Ensembl=ENSGGOG00000010903.3|UniProtKB=A0A2I2YY45 A0A2I2YY45 POLR1C PTHR11800:SF13 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;RNA polymerase III complex#GO:0005666;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000010466.3|UniProtKB=A0A2I2ZUW6 A0A2I2ZUW6 PTHR45625:SF8 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000015630.3|UniProtKB=G3RHX0 G3RHX0 PECR PTHR24317:SF7 PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;diterpenoid metabolic process#GO:0016101;isoprenoid metabolic process#GO:0006720 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000011962.3|UniProtKB=G3S5P5 G3S5P5 ZRSR2 PTHR12620:SF4 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT ZINC FINGER (CCCH TYPE), RNA-BINDING MOTIF AND SERINE_ARGININE RICH 2 nucleic acid binding#GO:0003676;binding#GO:0005488;pre-mRNA binding#GO:0036002;RNA binding#GO:0003723 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000024466.2|UniProtKB=G3S0K3 G3S0K3 ERVFRD-1 PTHR10424:SF85 VIRAL ENVELOPE PROTEIN SYNCYTIN-2 animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146;myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000022215.2|UniProtKB=A0A2I2YI01 A0A2I2YI01 OLA1 PTHR23305:SF11 OBG GTPASE FAMILY OBG-LIKE ATPASE 1 hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000006130.3|UniProtKB=G3QTH6 G3QTH6 HNRNPA3 PTHR48026:SF12 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A3 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000009478.3|UniProtKB=G3RTP2 G3RTP2 PVALB PTHR11653:SF2 PARVALBUMIN ALPHA PARVALBUMIN ALPHA metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000008267.3|UniProtKB=A0A2I2ZC23 A0A2I2ZC23 HSPD1 PTHR45633:SF17 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 positive regulation of immune system process#GO:0002684;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;protein maturation#GO:0051604;positive regulation of macromolecule metabolic process#GO:0010604;lymphocyte activation#GO:0046649;cellular component organization or biogenesis#GO:0071840;apoptotic process#GO:0006915;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;immune system process#GO:0002376;cellular localization#GO:0051641;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;transport#GO:0006810;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;positive regulation of type I interferon production#GO:0032481;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;cellular response to topologically incorrect protein#GO:0035967;positive regulation of lymphocyte activation#GO:0051251;response to stress#GO:0006950;positive regulation of cell-cell adhesion#GO:0022409;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;regulation of multicellular organismal process#GO:0051239;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;metabolic process#GO:0008152;positive regulation of leukocyte activation#GO:0002696;T cell activation#GO:0042110;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of lymphocyte activation#GO:0051249;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;response to unfolded protein#GO:0006986;regulation of macromolecule biosynthetic process#GO:0010556;mitochondrial protein import pathway#GO:7770058;regulation of leukocyte cell-cell adhesion#GO:1903037;establishment of localization#GO:0051234;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;leukocyte activation#GO:0045321;cell death#GO:0008219;positive regulation of cell adhesion#GO:0045785;positive regulation of cytokine production#GO:0001819;cellular response to unfolded protein#GO:0034620;cell activation#GO:0001775;protein metabolic process#GO:0019538;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891 cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000004326.3|UniProtKB=G3QNW5 G3QNW5 PITHD1 PTHR12175:SF7 AD039 HT014 THIOREDOXIN FAMILY TRP26 PITH DOMAIN-CONTAINING PROTEIN 1 regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;regulation of cell development#GO:0060284;positive regulation of biological process#GO:0048518;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of cellular process#GO:0048522;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of myeloid cell differentiation#GO:0045637;regulation of hemopoiesis#GO:1903706;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000003992.3|UniProtKB=G3QN13 G3QN13 PTHR24230:SF17 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 3 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000028160.2|UniProtKB=G3S4N0 G3S4N0 PIGM PTHR12886:SF0 PIG-M MANNOSYLTRANSFERASE GPI ALPHA-1,4-MANNOSYLTRANSFERASE I, CATALYTIC SUBUNIT catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mannosyltransferase complex#GO:0031501;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000005658.3|UniProtKB=G3RTP7 G3RTP7 PTHR11241:SF11 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, MITOCHONDRIAL binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;small molecule binding#GO:0036094;ion binding#GO:0043167;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;magnesium ion binding#GO:0000287;cation binding#GO:0043169;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside triphosphate diphosphatase activity#GO:0047429 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;nucleoside monophosphate metabolic process#GO:0009123;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate biosynthetic process#GO:0009124;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleotide catabolic process#GO:0009166;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086 hydrolase#PC00121;phosphatase#PC00181 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUTP pyrophosphatase#P02918 GORGO|Ensembl=ENSGGOG00000009408.4|UniProtKB=G3R1W1 G3R1W1 ITGB6 PTHR10082:SF11 INTEGRIN BETA SUBUNIT INTEGRIN BETA-6 binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;cell migration#GO:0016477;cell adhesion mediated by integrin#GO:0033627;cell surface receptor signaling pathway#GO:0007166 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;signaling receptor complex#GO:0043235;cell junction#GO:0030054;integrin complex#GO:0008305;anchoring junction#GO:0070161 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 GORGO|Ensembl=ENSGGOG00000024933.2|UniProtKB=G3SF89 G3SF89 PTHR24058:SF51 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001035.3|UniProtKB=G3QFE9 G3QFE9 DNTT PTHR11276:SF21 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA NUCLEOTIDYLEXOTRANSFERASE DNA-directed DNA polymerase activity#GO:0003887;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000013809.3|UniProtKB=G3RD87 G3RD87 KIF14 PTHR24115:SF546 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF14 cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;brain development#GO:0007420;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;head development#GO:0060322;establishment of vesicle localization#GO:0051650;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810;developmental process#GO:0032502;transport along microtubule#GO:0010970;animal organ development#GO:0048513;establishment of localization#GO:0051234;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;establishment of organelle localization#GO:0051656;forebrain development#GO:0030900;microtubule-based movement#GO:0007018;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000022396.2|UniProtKB=A0A2I2ZD04 A0A2I2ZD04 C15H14orf28 PTHR35350:SF1 HYPOTHETICAL LOC314168 DOPAMINE RECEPTOR-INTERACTING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000041551.1|UniProtKB=A0A2I2YFG9 A0A2I2YFG9 PTHR10317:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E N-TERMINAL DOMAIN-CONTAINING PROTEIN translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000004124.3|UniProtKB=G3QND8 G3QND8 CCDC30 PTHR34479:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 30 COILED-COIL DOMAIN-CONTAINING PROTEIN 30 GORGO|Ensembl=ENSGGOG00000001811.3|UniProtKB=A0A2I2YRU5 A0A2I2YRU5 KCTD3 PTHR15859:SF2 SETA BINDING PROTEIN 1 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD3 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000496.3|UniProtKB=G3QE04 G3QE04 TCAIM PTHR31596:SF1 T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000039691.1|UniProtKB=A0A2I2Z2L8 A0A2I2Z2L8 LHFPL4 PTHR12489:SF14 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 4 PROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;GABA receptor binding#GO:0050811;protein binding#GO:0005515 macromolecule localization#GO:0033036;cellular process#GO:0009987;multicellular organismal process#GO:0032501;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;system process#GO:0003008;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;cell junction organization#GO:0034330;sensory perception of sound#GO:0007605;postsynapse organization#GO:0099173;nervous system process#GO:0050877;synapse organization#GO:0050808;localization within membrane#GO:0051668;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;receptor clustering#GO:0043113;cellular localization#GO:0051641;localization#GO:0051179 cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000043594.1|UniProtKB=A0A2I2ZNF6 A0A2I2ZNF6 ZNF597 PTHR24381:SF248 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 597 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005220.3|UniProtKB=G3QR78 G3QR78 TIMM44 PTHR10721:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004597.3|UniProtKB=G3S8Y7 G3S8Y7 SEPTIN2 PTHR18884:SF67 SEPTIN SEPTIN-2 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cytokinesis#GO:0000910;cilium organization#GO:0044782;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;cell cycle process#GO:0022402;cell division#GO:0051301;cell cycle#GO:0007049;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 GORGO|Ensembl=ENSGGOG00000009771.3|UniProtKB=G3SJ48 G3SJ48 PSMB2 PTHR11599:SF6 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-2 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000006954.3|UniProtKB=G3QVM0 G3QVM0 PTHR11711:SF334 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4A nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000008484.3|UniProtKB=G3S107 G3S107 ZDHHC1 PTHR22883:SF8 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC1 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 response to virus#GO:0009615;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;protein targeting#GO:0006605;response to stimulus#GO:0050896;antiviral innate immune response#GO:0140374;defense response to virus#GO:0051607;defense response#GO:0006952;response to external stimulus#GO:0009605;establishment of localization#GO:0051234;innate immune response#GO:0045087;protein targeting to membrane#GO:0006612;response to other organism#GO:0051707;defense response to other organism#GO:0098542;cellular process#GO:0009987;immune response#GO:0006955;defense response to symbiont#GO:0140546;establishment of protein localization#GO:0045184;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;establishment of protein localization to membrane#GO:0090150 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000025817.2|UniProtKB=G3S1Y9 G3S1Y9 VWA5A PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A GORGO|Ensembl=ENSGGOG00000011120.3|UniProtKB=G3R698 G3R698 AP3M1 PTHR10529:SF342 AP COMPLEX SUBUNIT MU AP-3 COMPLEX SUBUNIT MU-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;receptor-mediated endocytosis#GO:0006898;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;receptor internalization#GO:0031623;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological quality#GO:0065008;post-Golgi vesicle-mediated transport#GO:0006892;endocytosis#GO:0006897;postsynaptic neurotransmitter receptor internalization#GO:0098884 AP-type membrane coat adaptor complex#GO:0030119;Golgi apparatus#GO:0005794;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000014045.3|UniProtKB=A0A2I2ZIR5 A0A2I2ZIR5 VGLL2 PTHR15950:SF17 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 2 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000014221.3|UniProtKB=G3SDV1 G3SDV1 MLST8 PTHR19842:SF0 G BETA-LIKE PROTEIN GBL TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of actin filament-based process#GO:0032970;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;TOR signaling#GO:0031929 intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000015462.3|UniProtKB=A0A2I2YA57 A0A2I2YA57 DDX11 PTHR11472:SF41 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER ATP-DEPENDENT DNA HELICASE DDX11-RELATED ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678 chromosome organization#GO:0051276;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000024734.2|UniProtKB=A0A2I2ZLH0 A0A2I2ZLH0 LOC101138468 PTHR11715:SF26 GLYCINE CLEAVAGE SYSTEM H PROTEIN GLYCINE CLEAVAGE SYSTEM H PROTEIN amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000009591.3|UniProtKB=G3R2B5 G3R2B5 EEF1E1 PTHR44490:SF1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 enzyme activator activity#GO:0008047;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 positive regulation of apoptotic process#GO:0043065;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stress#GO:0080134;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of cellular response to stress#GO:0080135;positive regulation of signaling#GO:0023056;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000042670.1|UniProtKB=A0A2I2ZVE6 A0A2I2ZVE6 LOC109025893 PTHR11911:SF74 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 GORGO|Ensembl=ENSGGOG00000001679.3|UniProtKB=A0A2I2ZRH7 A0A2I2ZRH7 PKP4 PTHR10372:SF8 PLAKOPHILLIN-RELATED PLAKOPHILIN-4 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 intermediate filament binding protein#PC00130;cytoskeletal protein#PC00085;intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000007651.3|UniProtKB=A0A2I2YMN7 A0A2I2YMN7 SLC38A11 PTHR22950:SF708 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 GORGO|Ensembl=ENSGGOG00000024667.2|UniProtKB=A0A2I2ZXC2 A0A2I2ZXC2 LOC101140310 PTHR43416:SF15 DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000007296.3|UniProtKB=A0A2I2Y8C0 A0A2I2Y8C0 PHYHIP PTHR15698:SF9 PROTEIN CBG15099 PHYTANOYL-COA HYDROXYLASE-INTERACTING PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000015218.3|UniProtKB=A0A2I2YNL4 A0A2I2YNL4 RAB21 PTHR24070:SF447 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAB-21 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000012350.3|UniProtKB=G3R9H9 G3R9H9 SEZ6 PTHR45656:SF1 PROTEIN CBR-CLEC-78 SEIZURE PROTEIN 6 HOMOLOG regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;biological regulation#GO:0065007;head development#GO:0060322;nervous system development#GO:0007399;developmental maturation#GO:0021700;brain development#GO:0007420;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of developmental process#GO:0050793;central nervous system development#GO:0007417;regulation of cellular component organization#GO:0051128;regulation of dendrite development#GO:0050773;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856 endoplasmic reticulum#GO:0005783;cell junction#GO:0030054;neuron projection#GO:0043005;endomembrane system#GO:0012505;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;dendritic spine#GO:0043197;cell body#GO:0044297;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000010570.3|UniProtKB=A0A2I2ZZ42 A0A2I2ZZ42 MSRB2 PTHR10173:SF37 METHIONINE SULFOXIDE REDUCTASE METHIONINE-R-SULFOXIDE REDUCTASE B2, MITOCHONDRIAL oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 reductase#PC00198;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000012752.3|UniProtKB=G3RAG7 G3RAG7 CARNMT1 PTHR12303:SF14 CARNOSINE N-METHYLTRANSFERASE PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE CARNMT1 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000011066.3|UniProtKB=G3R651 G3R651 AKR1E2 PTHR11732:SF391 ALDO/KETO REDUCTASE 1,5-ANHYDRO-D-FRUCTOSE REDUCTASE alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000001930.3|UniProtKB=G3RRA9 G3RRA9 CHD4 PTHR45623:SF22 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD4 ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;DNA binding#GO:0003677;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000003351.3|UniProtKB=G3QLE3 G3QLE3 IL1RL2 PTHR11890:SF9 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR-LIKE 2 cell communication#GO:0007154;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of response to external stimulus#GO:0032101;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000022663.2|UniProtKB=G3RSV4 G3RSV4 PTHR12757:SF5 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 3 transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phosphatidylinositol transfer activity#GO:0008526;lipid transfer activity#GO:0120013 lipid localization#GO:0010876;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;localization#GO:0051179;regulation of biological process#GO:0050789;organophosphate ester transport#GO:0015748;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;transport#GO:0006810;regulation of response to stimulus#GO:0048583;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid transport#GO:0006869;biological regulation#GO:0065007;phospholipid transport#GO:0015914;regulation of signal transduction#GO:0009966 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000008760.3|UniProtKB=A0A2I2YKH4 A0A2I2YKH4 ATOX1 PTHR46365:SF1 COPPER TRANSPORT PROTEIN ATOX1 COPPER TRANSPORT PROTEIN ATOX1 molecular carrier activity#GO:0140104 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011726.3|UniProtKB=Q95M68 Q95M68 DEFB1 PTHR21388:SF9 BETA-DEFENSIN-RELATED BETA-DEFENSIN 1 signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;chemokine receptor binding#GO:0042379 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010213.4|UniProtKB=A0A2I2YCS6 A0A2I2YCS6 GPHN PTHR10192:SF33 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN GEPHYRIN transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;membrane organization#GO:0061024;metabolic process#GO:0008152;intracellular protein localization#GO:0008104;neuromuscular junction development#GO:0007528;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;postsynapse organization#GO:0099173;cell junction organization#GO:0034330;synapse organization#GO:0050808;receptor clustering#GO:0043113;localization within membrane#GO:0051668;localization#GO:0051179;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641 plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054;synaptic membrane#GO:0097060;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;dendritic tree#GO:0097447 GORGO|Ensembl=ENSGGOG00000025122.2|UniProtKB=A0A2I2ZCU7 A0A2I2ZCU7 IMP3 PTHR11831:SF1 30S 40S RIBOSOMAL PROTEIN U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3 rRNA binding#GO:0019843;snoRNA binding#GO:0030515;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;ribosome#GO:0005840;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000043723.1|UniProtKB=A0A2I2YGV7 A0A2I2YGV7 C2H3orf80 PTHR38505:SF1 HYPOTHETICAL PROTEIN LOC100362176 SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 80 GORGO|Ensembl=ENSGGOG00000004477.3|UniProtKB=A0A2I2YVM9 A0A2I2YVM9 MCF2 PTHR22826:SF146 RHO GUANINE EXCHANGE FACTOR-RELATED PROTO-ONCOGENE DBL guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;dendrite development#GO:0016358;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000025267.2|UniProtKB=G3RPL4 G3RPL4 C1QL1 PTHR22923:SF64 CEREBELLIN-RELATED C1Q-RELATED FACTOR extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013941.3|UniProtKB=A0A2I2YV80 A0A2I2YV80 C5H6orf89 PTHR35259:SF1 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 GORGO|Ensembl=ENSGGOG00000004035.3|UniProtKB=G3QN57 G3QN57 LRP8 PTHR24270:SF3 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 8 developmental process#GO:0032502;transport#GO:0006810;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;central nervous system development#GO:0007417;endocytosis#GO:0006897 membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853;caveola#GO:0005901;membrane#GO:0016020;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000005620.3|UniProtKB=G3S921 G3S921 VTI1B PTHR21230:SF64 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B protein binding#GO:0005515;SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;binding#GO:0005488 vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization#GO:0051234;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;membrane organization#GO:0061024;macroautophagy#GO:0016236;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle fusion#GO:0006906;catabolic process#GO:0009056;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152;endosomal transport#GO:0016197;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;post-Golgi vesicle-mediated transport#GO:0006892;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;cellular component organization#GO:0016043;cytosolic transport#GO:0016482 vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;ER to Golgi transport vesicle membrane#GO:0012507;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;endoplasmic reticulum#GO:0005783;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588 SNARE protein#PC00034;membrane traffic protein#PC00150 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 GORGO|Ensembl=ENSGGOG00000027268.2|UniProtKB=G3S907 G3S907 OTOL1 PTHR24023:SF914 COLLAGEN ALPHA OTOLIN-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000015208.3|UniProtKB=G3RGT6 G3RGT6 NDRG1 PTHR11034:SF18 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG1 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000006698.3|UniProtKB=G3QUZ0 G3QUZ0 PTHR11394:SF23 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 14 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000041063.1|UniProtKB=A0A2I2YVU8 A0A2I2YVU8 PTHR47963:SF14 DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL RNA HELICASE ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000007085.3|UniProtKB=G3QVZ2 G3QVZ2 MDH1 PTHR23382:SF34 MALATE DEHYDROGENASE MALATE DEHYDROGENASE, CYTOPLASMIC catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing compound metabolic process#GO:0006139;pyridine-containing compound metabolic process#GO:0072524;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 TCA cycle#P00051>Malate Dehydrogenase#P01270 GORGO|Ensembl=ENSGGOG00000001108.3|UniProtKB=G3QFL4 G3QFL4 HS3ST5 PTHR10605:SF46 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 5 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000016995.3|UniProtKB=G3RLE5 G3RLE5 PPA1 PTHR10286:SF47 INORGANIC PYROPHOSPHATASE INORGANIC PYROPHOSPHATASE hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 metabolic process#GO:0008152;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 pyrophosphatase#PC00196 GORGO|Ensembl=ENSGGOG00000037773.1|UniProtKB=A0A2I2Y8B2 A0A2I2Y8B2 PTHR23073:SF70 26S PROTEASOME REGULATORY SUBUNIT ATPASE AAA-TYPE CORE DOMAIN-CONTAINING PROTEIN isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 proteasome complex#GO:0000502;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 GORGO|Ensembl=ENSGGOG00000044206.1|UniProtKB=A0A2I2ZP65 A0A2I2ZP65 TMEM234 PTHR28668:SF1 TRANSMEMBRANE PROTEIN 234 TRANSMEMBRANE PROTEIN 234 GORGO|Ensembl=ENSGGOG00000001672.3|UniProtKB=G3QH29 G3QH29 LOC101141051 PTHR22654:SF2 G PROTEIN PATHWAY SUPPRESSOR 2 G PROTEIN PATHWAY SUPPRESSOR 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000016105.3|UniProtKB=G3RJ38 G3RJ38 NEDD8 PTHR10666:SF173 UBIQUITIN UBIQUITIN-LIKE PROTEIN NEDD8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;nucleus#GO:0005634;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000003901.3|UniProtKB=G3QMT6 G3QMT6 STRBP PTHR45762:SF1 ZINC FINGER RNA-BINDING PROTEIN SPERMATID PERINUCLEAR RNA-BINDING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000038715.1|UniProtKB=A0A2I2YXJ5 A0A2I2YXJ5 LOC101126398 PTHR21353:SF8 FAMILY NOT NAMED CARDIOTROPHIN-2 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;cell surface receptor signaling pathway via STAT#GO:0097696;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;multicellular organism development#GO:0007275 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000081.3|UniProtKB=G3QCX8 G3QCX8 ZYX PTHR24212:SF1 ZYXIN/TRIP6 ZYXIN cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to transforming growth factor beta#GO:0071559;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;response to endogenous stimulus#GO:0009719;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179 intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;stress fiber#GO:0001725;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;actomyosin#GO:0042641;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000025349.2|UniProtKB=G3RXP7 G3RXP7 ACR PTHR24252:SF8 ACROSIN-RELATED ACROSIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;sexual reproduction#GO:0019953;catabolic process#GO:0009056;fertilization#GO:0009566;reproductive process#GO:0022414;primary metabolic process#GO:0044238;single fertilization#GO:0007338;cellular process#GO:0009987;acrosome reaction#GO:0007340 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000000888.3|UniProtKB=A0A2I2Z2Y3 A0A2I2Z2Y3 DENND10 PTHR28544:SF1 PROTEIN FAM45A-RELATED DENN DOMAIN-CONTAINING PROTEIN 10-RELATED enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 protein transport#GO:0015031;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000011015.3|UniProtKB=G3R5Z7 G3R5Z7 ECRG4 PTHR31613:SF2 AUGURIN AUGURIN system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;developmental process#GO:0032502;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;animal gross anatomical part developmental process#GO:0160108;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;response to stimulus#GO:0050896;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;multicellular organism development#GO:0007275;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;nervous system development#GO:0007399 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010383.3|UniProtKB=G3R4C4 G3R4C4 TMEM37 PTHR31767:SF0 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-LIKE SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-LIKE SUBUNIT voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000013199.3|UniProtKB=G3RBL8 G3RBL8 SGCA PTHR10132:SF16 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER ALPHA-SARCOGLYCAN plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000026188.2|UniProtKB=G3RW14 G3RW14 LOC101139480 PTHR26450:SF140 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51G1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004817.3|UniProtKB=G3QQ63 G3QQ63 ZDHHC13 PTHR24161:SF16 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE ZDHHC13 catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002941.3|UniProtKB=G3QKB9 G3QKB9 FGF5 PTHR11486:SF23 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 5 protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018 response to fibroblast growth factor#GO:0071774;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000001508.3|UniProtKB=A0A2I2Z235 A0A2I2Z235 SRRT PTHR13165:SF0 ARSENITE-RESISTANCE PROTEIN 2 SERRATE RNA EFFECTOR MOLECULE HOMOLOG RNA binding#GO:0003723;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;primary miRNA processing#GO:0031053;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 GORGO|Gene=MT-ND4L|UniProtKB=Q34572 Q34572 MT-ND4L PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000001000.3|UniProtKB=G3RZ78 G3RZ78 NKIRAS2 PTHR46152:SF2 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 GORGO|Ensembl=ENSGGOG00000013540.3|UniProtKB=G3RCI0 G3RCI0 SUGP2 PTHR23340:SF2 ARGININE/SERINE RICH SPLICING FACTOR SF4/14 SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000007380.3|UniProtKB=G3QWQ8 G3QWQ8 SCNN1G PTHR11690:SF19 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED EPITHELIAL SODIUM CHANNEL SUBUNIT GAMMA passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000015742.3|UniProtKB=G3RYX9 G3RYX9 PTHR24103:SF662 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 73-RELATED acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000041512.1|UniProtKB=A0A2I2ZAG4 A0A2I2ZAG4 PTHR10256:SF1 SELENIDE, WATER DIKINASE SELENIDE, WATER DIKINASE 2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000011815.3|UniProtKB=G3SCX4 G3SCX4 TPX2 PTHR14326:SF67 TARGETING PROTEIN FOR XKLP2 TARGETING PROTEIN FOR XKLP2 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;nuclear division#GO:0000280;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000015123.3|UniProtKB=G3S810 G3S810 PTCD1 PTHR24014:SF6 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;tRNA binding#GO:0000049 mitochondrial RNA modification#GO:1900864;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;mitochondrial RNA metabolic process#GO:0000959;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;tRNA 3'-end processing#GO:0042780;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000027342.2|UniProtKB=G3RZV7 G3RZV7 CSKMT PTHR12176:SF83 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN CITRATE SYNTHASE-LYSINE N-METHYLTRANSFERASE CSKMT, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012624.4|UniProtKB=G3RA58 G3RA58 SKAP1 PTHR15129:SF1 SRC-ASSOCIATED ADAPTOR PROTEIN SRC KINASE-ASSOCIATED PHOSPHOPROTEIN 1 regulation of immune response#GO:0050776;cell communication#GO:0007154;positive regulation of cell adhesion#GO:0045785;cellular response to stimulus#GO:0051716;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of leukocyte cell-cell adhesion#GO:1903037;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;immune response-regulating cell surface receptor signaling pathway#GO:0002768;immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000044201.1|UniProtKB=G3RES3 G3RES3 EPPIN PTHR46751:SF2 EPPIN EPPIN regulation of microtubule-based process#GO:0032886;negative regulation of cellular process#GO:0048523;regulation of cell motility#GO:2000145;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;regulation of reproductive process#GO:2000241;regulation of locomotion#GO:0040012;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000027423.2|UniProtKB=G3RMV7 G3RMV7 INVS PTHR24178:SF2 MOLTING PROTEIN MLT-4 INVERSIN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;localization#GO:0051179;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;intracellular protein localization#GO:0008104;system development#GO:0048731;kidney development#GO:0001822;macromolecule localization#GO:0033036;renal system development#GO:0072001;multicellular organismal process#GO:0032501;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512 cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000025826.2|UniProtKB=A0A2I2ZSE4 A0A2I2ZSE4 PTHR47009:SF9 HEPATITIS A VIRUS CELLULAR RECEPTOR 1 HOMOLOG IG-LIKE DOMAIN-CONTAINING PROTEIN virus receptor activity#GO:0001618;phospholipid binding#GO:0005543;protein binding#GO:0005515;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167 cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;localization#GO:0051179;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell activation#GO:0050867;regulation of multicellular organismal process#GO:0051239;membrane organization#GO:0061024;biological regulation#GO:0065007;phagocytosis#GO:0006909;transport#GO:0006810;positive regulation of leukocyte activation#GO:0002696;membrane invagination#GO:0010324;import into cell#GO:0098657;establishment of localization#GO:0051234;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005076.3|UniProtKB=A0A2I2ZUF5 A0A2I2ZUF5 PEX1 PTHR23077:SF12 AAA-FAMILY ATPASE PEROXISOMAL ATPASE PEX1 ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111 peroxisomal transport#GO:0043574;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;peroxisome organization#GO:0007031;protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;organelle organization#GO:0006996;macromolecule localization#GO:0033036 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;cytosol#GO:0005829;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000011232.3|UniProtKB=G3RYY7 G3RYY7 SLC4A7 PTHR11453:SF105 ANION EXCHANGE PROTEIN SODIUM BICARBONATE COTRANSPORTER 3 bicarbonate transmembrane transporter activity#GO:0015106;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 neurogenesis#GO:0022008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;developmental process#GO:0032502;epidermis development#GO:0008544;sensory organ development#GO:0007423;biological regulation#GO:0065007;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;inner ear development#GO:0048839;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;animal organ development#GO:0048513;multicellular organism development#GO:0007275;chemical homeostasis#GO:0048878;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;hair cell differentiation#GO:0035315;ear development#GO:0043583;regulation of biological quality#GO:0065008;neuron development#GO:0048666;transmembrane transport#GO:0055085;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;intracellular monoatomic ion homeostasis#GO:0006873 apical part of cell#GO:0045177;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;basolateral plasma membrane#GO:0016323 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000025184.2|UniProtKB=G3SFV6 G3SFV6 TOMM20 PTHR12430:SF2 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG establishment of RNA localization#GO:0051236;mitochondrial transport#GO:0006839;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;nucleic acid transport#GO:0050657;mitochondrial transmembrane transport#GO:1990542;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000010710.3|UniProtKB=G3R581 G3R581 LMTK3 PTHR24417:SF2 SERINE/THREONINE-PROTEIN KINASE LMTK1 SERINE_THREONINE-PROTEIN KINASE LMTK3 protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000001984.3|UniProtKB=A0A2I2Z5E0 A0A2I2Z5E0 TBCD PTHR12658:SF1 BETA-TUBULIN COFACTOR D TUBULIN-SPECIFIC CHAPERONE D molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;binding#GO:0005488;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;enzyme activator activity#GO:0008047 cytoskeleton organization#GO:0007010;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;metabolic process#GO:0008152;protein folding#GO:0006457;cell junction organization#GO:0034330;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000013952.3|UniProtKB=G3RX85 G3RX85 PRPF39 PTHR17204:SF5 PRE-MRNA PROCESSING PROTEIN PRP39-RELATED PRE-MRNA-PROCESSING FACTOR 39 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002;binding#GO:0005488 mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000024414.2|UniProtKB=G3SES3 G3SES3 PTHR46254:SF7 PROTEIN GVQW1-RELATED MITOCHONDRIAL RIBOSOMAL PROTEIN L33 GORGO|Ensembl=ENSGGOG00000041583.1|UniProtKB=A0A2I2ZB58 A0A2I2ZB58 RNASE11 PTHR11437:SF22 RIBONUCLEASE INACTIVE RIBONUCLEASE 11-RELATED catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;response to external stimulus#GO:0009605;defense response#GO:0006952;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000023925.2|UniProtKB=G3S258 G3S258 NUTF2 PTHR12612:SF46 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000014096.3|UniProtKB=G3RDZ2 G3RDZ2 PLEKHG7 PTHR13217:SF6 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 GORGO|Ensembl=ENSGGOG00000011059.3|UniProtKB=A0A2I2YWF4 A0A2I2YWF4 SLIRP PTHR48027:SF38 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED SRA STEM-LOOP-INTERACTING RNA-BINDING PROTEIN, MITOCHONDRIAL RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016706.3|UniProtKB=G3RKM4 G3RKM4 PTHR46452:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 protein binding#GO:0005515;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000042074.1|UniProtKB=A0A2I2YMX4 A0A2I2YMX4 PTHR10369:SF44 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN L36A LIKE structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010300.3|UniProtKB=G3RNU9 G3RNU9 PLG PTHR24261:SF13 PLASMINOGEN-RELATED PLASMINOGEN binding#GO:0005488;signaling receptor binding#GO:0005102;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of wound healing#GO:0061041;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;negative regulation of hemostasis#GO:1900047;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;negative regulation of coagulation#GO:0050819;protein metabolic process#GO:0019538;cellular process#GO:0009987;regulation of hemostasis#GO:1900046;negative regulation of wound healing#GO:0061045;regulation of response to wounding#GO:1903034;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;regulation of coagulation#GO:0050818;fibrinolysis#GO:0042730;regulation of response to stimulus#GO:0048583;negative regulation of blood coagulation#GO:0030195;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;negative regulation of response to wounding#GO:1903035;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 Blood coagulation#P00011>Plasmin#P00415;Blood coagulation#P00011>Plasminogen#P00408;Plasminogen activating cascade#P00050>Plasminogen#P01255;Plasminogen activating cascade#P00050>Plasmin#P01246 GORGO|Ensembl=ENSGGOG00000040761.1|UniProtKB=A0A2I2Y534 A0A2I2Y534 SYN3 PTHR10841:SF6 SYNAPSIN SYNAPSIN-3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cytoskeletal adaptor activity#GO:0008093 cellular localization#GO:0051641;localization#GO:0051179;organelle localization#GO:0051640;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization#GO:0016043;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000005425.3|UniProtKB=G3QRP8 G3QRP8 ZNF32 PTHR23226:SF214 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 32 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002886.3|UniProtKB=G3QK68 G3QK68 NOP56 PTHR10894:SF0 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 56 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515 ribonucleoprotein complex#GO:1990904;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015319.3|UniProtKB=G3RH35 G3RH35 NFKBID PTHR24124:SF7 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR DELTA regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000003580.3|UniProtKB=G3QLZ1 G3QLZ1 SLC7A4 PTHR43243:SF108 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 GORGO|Ensembl=ENSGGOG00000016691.3|UniProtKB=G3RKL5 G3RKL5 GEMIN2 PTHR12794:SF6 GEMIN2 GEM-ASSOCIATED PROTEIN 2 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000006546.3|UniProtKB=G3QUK3 G3QUK3 PTHR15492:SF3 CYCLIN D1-BINDING PROTEIN 1 CYCLIN-D1-BINDING PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000012812.3|UniProtKB=G3RAM1 G3RAM1 EGFL6 PTHR24050:SF24 PA14 DOMAIN-CONTAINING PROTEIN EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 6 GORGO|Gene=ASPM|UniProtKB=P62289 P62289 ASPM PTHR22706:SF1 ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES protein binding#GO:0005515;binding#GO:0005488;calmodulin binding#GO:0005516 meiotic cell cycle#GO:0051321;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293;cytoskeleton organization#GO:0007010;organelle localization#GO:0051640;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;spindle localization#GO:0051653;localization#GO:0051179;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle#GO:0007049;cell cycle process#GO:0022402;establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000006412.3|UniProtKB=A0A2I2Y8W4 A0A2I2Y8W4 CRAT PTHR22589:SF50 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987 peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000043579.1|UniProtKB=A0A2I2ZWE8 A0A2I2ZWE8 SMIM10L1 PTHR34446:SF5 SMALL INTEGRAL MEMBRANE PROTEIN 10 SMALL INTEGRAL MEMBRANE PROTEIN 10-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000008929.3|UniProtKB=A0A2I2ZG70 A0A2I2ZG70 LOC101133640 PTHR48002:SF15 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010555.3|UniProtKB=G3R4T0 G3R4T0 BRI3BP PTHR31253:SF0 BRI3-BINDING PROTEIN BRI3-BINDING PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000025902.2|UniProtKB=G3RNI7 G3RNI7 PTHR45883:SF6 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN-RELATED binding#GO:0005488;protein-folding chaperone binding#GO:0051087;heat shock protein binding#GO:0031072;protein binding#GO:0005515;Hsp70 protein binding#GO:0030544 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 GORGO|Ensembl=ENSGGOG00000004918.3|UniProtKB=G3SJ02 G3SJ02 PTHR43612:SF7 TRIFUNCTIONAL ENZYME SUBUNIT ALPHA TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000000647.3|UniProtKB=G3QEE3 G3QEE3 ZNF79 PTHR24381:SF344 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 79 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000041783.1|UniProtKB=A0A2I2ZF56 A0A2I2ZF56 PTHR21304:SF9 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000012217.3|UniProtKB=G3SAE6 G3SAE6 PLEC PTHR23169:SF20 ENVOPLAKIN PLECTIN protein binding#GO:0005515;structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 wound healing#GO:0042060;intermediate filament-based process#GO:0045103;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cell-substrate junction assembly#GO:0007044;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cell-substrate junction organization#GO:0150115;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;response to wounding#GO:0009611;cellular process#GO:0009987 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;sarcolemma#GO:0042383;cell junction#GO:0030054;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;perinuclear region of cytoplasm#GO:0048471;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 intermediate filament binding protein#PC00130;intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000005454.3|UniProtKB=A0A2I2YQP9 A0A2I2YQP9 PCCB PTHR43842:SF2 PROPIONYL-COA CARBOXYLASE BETA CHAIN PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;ligase#PC00142 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163;Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 GORGO|Ensembl=ENSGGOG00000001136.3|UniProtKB=G3QFP3 G3QFP3 ZNF440 PTHR24381:SF311 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 440 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000034869.2|UniProtKB=G3SKU7 G3SKU7 RXFP4 PTHR10489:SF951 CELL ADHESION MOLECULE RELAXIN-3 RECEPTOR 2 protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000010147.3|UniProtKB=A0A2I2Z581 A0A2I2Z581 MYBPC1 PTHR13817:SF27 TITIN MYOSIN-BINDING PROTEIN C, SLOW-TYPE structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856 M band#GO:0031430;intracellular organelle#GO:0043229;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;A band#GO:0031672;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000028175.2|UniProtKB=G3QVN6 G3QVN6 CCL3L3 PTHR12015:SF151 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 3-LIKE 1 signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cell surface receptor signaling pathway#GO:0007166;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;response to cytokine#GO:0034097;taxis#GO:0042330;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell motility#GO:2000147;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cell migration#GO:0016477;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cytokine-mediated signaling pathway#GO:0019221;cell chemotaxis#GO:0060326;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cell motility#GO:0048870;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000040990.1|UniProtKB=A0A2I2ZGE2 A0A2I2ZGE2 KCNK10 PTHR11003:SF32 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 10 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271 cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000006940.3|UniProtKB=G3QVM5 G3QVM5 KDM3A PTHR12549:SF7 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3A transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;histone modifying activity#GO:0140993;DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000001722.3|UniProtKB=G3QH72 G3QH72 CD200R1L PTHR21462:SF6 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of response to external stimulus#GO:0032101;regulation of immune system process#GO:0002682;negative regulation of response to stimulus#GO:0048585;regulation of inflammatory response#GO:0050727;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;regulation of response to stress#GO:0080134 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010305.3|UniProtKB=G3R478 G3R478 PTHR23138:SF190 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nucleocytoplasmic transport#GO:0006913;protein import into nucleus#GO:0006606;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003285.3|UniProtKB=G3QL78 G3QL78 PTHR14191:SF7 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF1 protein binding#GO:0005515;protein-membrane adaptor activity#GO:0043495;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to plasma membrane#GO:0072659;cellular process#GO:0009987;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012317.3|UniProtKB=G3R9D8 G3R9D8 HABP4 PTHR12299:SF30 HYALURONIC ACID-BINDING PROTEIN 4 INTRACELLULAR HYALURONAN-BINDING PROTEIN 4 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 positive regulation of protein metabolic process#GO:0051247;regulation of translational initiation#GO:0006446;positive regulation of translation#GO:0045727;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013611.3|UniProtKB=G3RCQ0 G3RCQ0 GANAB PTHR22762:SF162 ALPHA-GLUCOSIDASE NEUTRAL ALPHA-GLUCOSIDASE AB alpha-glucosidase activity#GO:0090599;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 glucosidase#PC00108 GORGO|Ensembl=ENSGGOG00000014298.3|UniProtKB=G3REG2 G3REG2 GPT PTHR11751:SF308 ALANINE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE 1 transaminase#PC00216;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000010240.3|UniProtKB=G3R410 G3R410 SHMT2 PTHR11680:SF28 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 GORGO|Ensembl=ENSGGOG00000006763.3|UniProtKB=G3QV59 G3QV59 GUCY2F PTHR11920:SF349 GUANYLYL CYCLASE RETINAL GUANYLYL CYCLASE 2 molecular transducer activity#GO:0060089;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;peptide receptor activity#GO:0001653 phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nervous system process#GO:0050877;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;sensory perception of light stimulus#GO:0050953;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;visual perception#GO:0007601;nucleoside phosphate metabolic process#GO:0006753;sensory perception#GO:0007600;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;system process#GO:0003008 non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005 lyase#PC00144;guanylate cyclase#PC00114 GORGO|Ensembl=ENSGGOG00000016617.3|UniProtKB=G3RKE5 G3RKE5 C20H19orf18 PTHR38000:SF1 RIKEN CDNA 2900092C05 RIKEN CDNA 2900092C05 GENE GORGO|Ensembl=ENSGGOG00000025372.2|UniProtKB=G3RTZ8 G3RTZ8 PMP2 PTHR11955:SF64 FATTY ACID BINDING PROTEIN MYELIN P2 PROTEIN anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;ion binding#GO:0043167;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289 fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid transport#GO:0006869;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000023650.2|UniProtKB=G3S343 G3S343 PTHR15221:SF0 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 3 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 3 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000006435.3|UniProtKB=A0A2I2ZMM0 A0A2I2ZMM0 PLEKHA7 PTHR12752:SF4 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 7 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;adherens junction organization#GO:0034332;cellular component biogenesis#GO:0044085;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cell adhesion#GO:0007155;cell-cell junction organization#GO:0045216;protein-containing complex organization#GO:0043933;cell-cell junction maintenance#GO:0045217;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;cell junction#GO:0030054;adherens junction#GO:0005912;anchoring junction#GO:0070161;apical junction complex#GO:0043296 GORGO|Ensembl=ENSGGOG00000001202.3|UniProtKB=G3QFV5 G3QFV5 AHI1 PTHR44499:SF1 JOUBERIN JOUBERIN cilium organization#GO:0044782;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000025607.2|UniProtKB=G3RX22 G3RX22 GID4 PTHR15898:SF13 BIFUNCTIONAL APOPTOSIS REGULATOR GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000026210.2|UniProtKB=G3S3U5 G3S3U5 PTHR23267:SF331 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-15-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000325.3|UniProtKB=G3QDJ8 G3QDJ8 NOVA2 PTHR10288:SF162 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN NOVA-2 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of mRNA splicing, via spliceosome#GO:0048024;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;nucleic acid biosynthetic process#GO:0141187 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009551.4|UniProtKB=G3R287 G3R287 TTLL10 PTHR46810:SF1 INACTIVE POLYGLYCYLASE TTLL10 INACTIVE POLYGLYCYLASE TTLL10 ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;catalytic activity#GO:0003824 GORGO|Ensembl=ENSGGOG00000005213.3|UniProtKB=A0A2I2ZC79 A0A2I2ZC79 POLR2F PTHR47227:SF5 DNA-DIRECTED RNA POLYMERASE SUBUNIT K DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 catalytic activity, acting on RNA#GO:0140098;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 GORGO|Ensembl=ENSGGOG00000012995.3|UniProtKB=G3RB43 G3RB43 PTHR12634:SF15 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 2 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000011287.3|UniProtKB=G3R6P1 G3R6P1 MXD1 PTHR11969:SF18 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000013561.3|UniProtKB=G3RCJ5 G3RCJ5 GNA14 PTHR10218:SF213 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-14 ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 response to oxygen-containing compound#GO:1901700;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;regulation of biological quality#GO:0065008;cell communication#GO:0007154;action potential#GO:0001508;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of membrane potential#GO:0042391;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234 heterotrimeric G-protein#PC00117;G-protein#PC00020 PI3 kinase pathway#P00048>Galpha#P01199;Wnt signaling pathway#P00057>Galpha#P01451;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Endothelin signaling pathway#P00019>Gq#P00586;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073 GORGO|Ensembl=ENSGGOG00000011294.3|UniProtKB=G3R6P6 G3R6P6 KLK6 PTHR24271:SF19 KALLIKREIN-RELATED KALLIKREIN-6 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000004617.3|UniProtKB=G3QPM5 G3QPM5 PTHR16676:SF0 SIGNAL TRANSDUCER CD24 SIGNAL TRANSDUCER CD24 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 cell activation#GO:0001775;cellular process#GO:0009987;regulation of biological process#GO:0050789;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell-cell adhesion#GO:0022407;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;membrane microdomain#GO:0098857;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020;membrane raft#GO:0045121 GORGO|Ensembl=ENSGGOG00000023242.2|UniProtKB=A0A2I2YNE7 A0A2I2YNE7 PTHR44167:SF39 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED SERINE_THREONINE-PROTEIN KINASE CHK2 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;DNA integrity checkpoint signaling#GO:0031570;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;negative regulation of cell cycle#GO:0045786;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Chk2#P01484 GORGO|Ensembl=ENSGGOG00000007181.3|UniProtKB=G3QW79 G3QW79 TBC1D10A PTHR22957:SF215 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 10A molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000009632.3|UniProtKB=G3R2F5 G3R2F5 PTHR45945:SF2 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G PROTEIN SIGNALING 14 enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;cell cycle#GO:0007049;cell division#GO:0051301;microtubule cytoskeleton organization#GO:0000226;cognition#GO:0050890;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;spindle organization#GO:0007051;system process#GO:0003008;regulation of synaptic plasticity#GO:0048167;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;cellular component organization#GO:0016043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;positive regulation of synaptic transmission#GO:0050806;nervous system process#GO:0050877;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 GORGO|Ensembl=ENSGGOG00000016190.4|UniProtKB=A0A2I2ZP81 A0A2I2ZP81 PLXDC2 PTHR13055:SF11 TUMOR ENDOTHELIAL MARKER 7 RELATED PLEXIN DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000012867.3|UniProtKB=G3RAS3 G3RAS3 POFUT1 PTHR21420:SF3 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neurotic#P01115 GORGO|Ensembl=ENSGGOG00000013916.3|UniProtKB=G3S1Y4 G3S1Y4 PTHR13610:SF5 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN ADENINE NUCLEOTIDE TRANSLOCASE LYSINE N-METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000008865.3|UniProtKB=G3S3S9 G3S3S9 PTHR10395:SF12 URICASE AND TRANSTHYRETIN-RELATED TRANSTHYRETIN purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000041879.1|UniProtKB=A0A2I2Z6F9 A0A2I2Z6F9 LOC101134485 PTHR48002:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K15 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002093.3|UniProtKB=G3QI59 G3QI59 SCN4B PTHR13869:SF14 MYELIN P0 RELATED SODIUM CHANNEL REGULATORY SUBUNIT BETA-4 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;protein binding#GO:0005515;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;binding#GO:0005488;ion channel regulator activity#GO:0099106 cardiac muscle cell contraction#GO:0086003;regulation of membrane potential#GO:0042391;system process#GO:0003008;heart contraction#GO:0060047;regulation of system process#GO:0044057;muscle contraction#GO:0006936;multicellular organismal process#GO:0032501;cardiac muscle cell action potential involved in contraction#GO:0086002;blood circulation#GO:0008015;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;actin filament-based movement#GO:0030048;cellular process#GO:0009987;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;actin-mediated cell contraction#GO:0070252;regulation of heart contraction#GO:0008016;striated muscle contraction#GO:0006941;membrane depolarization#GO:0051899;heart process#GO:0003015;action potential#GO:0001508;muscle system process#GO:0003012;regulation of biological process#GO:0050789 sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000005678.3|UniProtKB=G3QSD2 G3QSD2 PRDM2 PTHR16515:SF37 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 2-RELATED transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000000018.3|UniProtKB=G3S7M3 G3S7M3 ZNF611 PTHR24377:SF741 IP01015P-RELATED ZINC FINGER PROTEIN 611 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002238.3|UniProtKB=A0A2I2Y1Q8 A0A2I2Y1Q8 ESRRB PTHR48092:SF7 KNIRPS-RELATED PROTEIN-RELATED STEROID HORMONE RECEPTOR ERR2 sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000010620.3|UniProtKB=G3R4Z3 G3R4Z3 PSMC1 PTHR23073:SF77 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 4 polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome complex#GO:0000502;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368 protease#PC00190 GORGO|Ensembl=ENSGGOG00000007650.3|UniProtKB=G3QXE1 G3QXE1 RPL34 PTHR46595:SF6 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000016197.3|UniProtKB=A0A2I2Y5U1 A0A2I2Y5U1 PIK3R2 PTHR10155:SF1 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699 membrane protein complex#GO:0098796;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168;Angiogenesis#P00005>PI3K#P00236;PI3 kinase pathway#P00048>p85#P01202;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;Integrin signalling pathway#P00034>PI3K#P00936;Axon guidance mediated by netrin#P00009>PI3K#P00363;VEGF signaling pathway#P00056>PI3K#P01413;T cell activation#P00053>PI3K#P01322;p53 pathway feedback loops 2#P04398>PI3K#P04661 GORGO|Ensembl=ENSGGOG00000001541.4|UniProtKB=A0A2I2Z4Q3 A0A2I2Z4Q3 USP25 PTHR24006:SF666 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 25 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;protein binding#GO:0005515;hydrolase activity#GO:0016787;binding#GO:0005488;deubiquitinase activity#GO:0101005 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000014046.3|UniProtKB=G3RDT5 G3RDT5 LYSMD1 PTHR20932:SF2 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 1-RELATED GORGO|Ensembl=ENSGGOG00000041217.1|UniProtKB=G3RRT5 G3RRT5 PTHR23266:SF100 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Gene=SEMG2|UniProtKB=Q5U7N3 Q5U7N3 SEMG2 PTHR10547:SF6 SEMENOGELIN/SEMINAL VESICLE SECRETORY PROTEIN SEMENOGELIN-2 spermatogenesis#GO:0007283;developmental process#GO:0032502;cell maturation#GO:0048469;cellular developmental process#GO:0048869;cellular process#GO:0009987;sperm capacitation#GO:0048240;developmental maturation#GO:0021700;male gamete generation#GO:0048232;sexual reproduction#GO:0019953;spermatid development#GO:0007286;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell differentiation#GO:0030154;gamete generation#GO:0007276 acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000039888.1|UniProtKB=G3SHJ3 G3SHJ3 LOC101136257 PTHR23430:SF398 HISTONE H2A HISTONE H2A TYPE 1-B_E structural molecule activity#GO:0005198 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component assembly#GO:0022607;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008257.3|UniProtKB=A0A2I2Y9E9 A0A2I2Y9E9 TCF7 PTHR10373:SF33 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 signaling#GO:0023052;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Gonadotropin-releasing hormone receptor pathway#P06664>TCF#P06701;Angiogenesis#P00005>TCF#P00242 GORGO|Ensembl=ENSGGOG00000000595.3|UniProtKB=G3QE94 G3QE94 PTHR11610:SF13 LIPASE ENDOTHELIAL LIPASE catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002106.3|UniProtKB=G3RQ65 G3RQ65 PKP2 PTHR10372:SF25 PLAKOPHILLIN-RELATED PLAKOPHILIN-2 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell junction organization#GO:0034330;protein localization to plasma membrane#GO:0072659;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;localization within membrane#GO:0051668;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;intermediate filament cytoskeleton organization#GO:0045104;circulatory system development#GO:0072359;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;intermediate filament organization#GO:0045109;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;heart development#GO:0007507;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;intermediate filament bundle assembly#GO:0045110;protein localization to cell periphery#GO:1990778 cell periphery#GO:0071944;nucleus#GO:0005634;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;adherens junction#GO:0005912;cell-cell contact zone#GO:0044291;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intercalated disc#GO:0014704;intracellular anatomical structure#GO:0005622 intermediate filament binding protein#PC00130;intermediate filament#PC00129;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000008755.3|UniProtKB=G3RVU5 G3RVU5 STK38 PTHR24356:SF221 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 38 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;establishment or maintenance of cell polarity#GO:0007163;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000012283.3|UniProtKB=G3R9A3 G3R9A3 OR52A5 PTHR26450:SF48 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52A5 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025838.2|UniProtKB=A0A2I2YYV8 A0A2I2YYV8 PTHR11852:SF7 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE 1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproductive process#GO:0022414 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007316.3|UniProtKB=G3QWJ9 G3QWJ9 REEP6 PTHR12300:SF133 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 6 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000004601.3|UniProtKB=A0A2I2ZHW2 A0A2I2ZHW2 MAP3K2 PTHR11584:SF393 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;JNK cascade#GO:0007254;response to stimulus#GO:0050896;p38MAPK cascade#GO:0038066;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000000038.3|UniProtKB=G3QCT9 G3QCT9 LRP5 PTHR46513:SF16 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 5 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Wnt signaling pathway#P00057>LRP5/6#P01431 GORGO|Ensembl=ENSGGOG00000002647.3|UniProtKB=G3RLX6 G3RLX6 SAMSN1 PTHR12301:SF4 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM DOMAIN-CONTAINING PROTEIN SAMSN-1 binding#GO:0005488;protein binding#GO:0005515 negative regulation of cell activation#GO:0050866;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;negative regulation of lymphocyte activation#GO:0051250;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of B cell activation#GO:0050864;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of lymphocyte activation#GO:0051249;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000008957.3|UniProtKB=G3SEC8 G3SEC8 ZFAND5 PTHR10634:SF26 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 5 GORGO|Ensembl=ENSGGOG00000023667.2|UniProtKB=A0A2I2ZHF9 A0A2I2ZHF9 PTHR31109:SF4 PROTEIN FAM207A FAMILY WITH SEQUENCE SIMILARITY 207 MEMBER A GORGO|Ensembl=ENSGGOG00000016728.3|UniProtKB=G3RKQ1 G3RKQ1 RNF40 PTHR23163:SF4 RING FINGER PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE BRE1B transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016935.3|UniProtKB=G3RL85 G3RL85 RHBDD2 PTHR11009:SF31 DER1-LIKE PROTEIN, DERLIN RHOMBOID DOMAIN-CONTAINING PROTEIN 2 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;response to unfolded protein#GO:0006986;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000026132.2|UniProtKB=G3RN30 G3RN30 ERO1B PTHR12613:SF2 ERO1-RELATED ERO1-LIKE PROTEIN BETA disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to unfolded protein#GO:0006986;cell communication#GO:0007154;protein metabolic process#GO:0019538;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;protein folding#GO:0006457 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000001517.3|UniProtKB=G3RMY5 G3RMY5 DPH5 PTHR10882:SF0 DIPHTHINE SYNTHASE DIPHTHINE METHYL ESTER SYNTHASE methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000013281.3|UniProtKB=G3RBU0 G3RBU0 PEBP1 PTHR11362:SF171 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 1 negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 GORGO|Ensembl=ENSGGOG00000011863.3|UniProtKB=G3R876 G3R876 FRMPD3 PTHR46221:SF1 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000012713.3|UniProtKB=A0A2I2ZVK0 A0A2I2ZVK0 SLC5A10 PTHR11819:SF128 SOLUTE CARRIER FAMILY 5 SODIUM_MANNOSE COTRANSPORTER SLC5A10 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;sugar transmembrane transporter activity#GO:0051119;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;solute:sodium symporter activity#GO:0015370 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008695.3|UniProtKB=G3R027 G3R027 ARAF PTHR23257:SF727 SERINE-THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000006420.3|UniProtKB=G3QU87 G3QU87 NPAS2 PTHR46055:SF1 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT NEURONAL PAS DOMAIN-CONTAINING PROTEIN 2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;circadian rhythm#GO:0007623;regulation of RNA metabolic process#GO:0051252;rhythmic process#GO:0048511;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000043006.1|UniProtKB=A0A2I2ZJP8 A0A2I2ZJP8 CHST3 PTHR10704:SF60 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000026591.2|UniProtKB=G3SCJ8 G3SCJ8 CSTF3 PTHR19980:SF0 RNA CLEAVAGE STIMULATION FACTOR CLEAVAGE STIMULATION FACTOR SUBUNIT 3 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000006817.3|UniProtKB=G3RPQ3 G3RPQ3 NFAT5 PTHR12533:SF10 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS 5 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;calcium-mediated signaling#GO:0019722;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;calcineurin-mediated signaling#GO:0097720;calcineurin-NFAT signaling cascade#GO:0033173;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of transcription by RNA polymerase II#GO:0045944;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851 GORGO|Ensembl=ENSGGOG00000003160.3|UniProtKB=G3QKX1 G3QKX1 RASSF6 PTHR22738:SF3 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 6 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012689.3|UniProtKB=G3RAB6 G3RAB6 MTM1 PTHR10807:SF69 MYOTUBULARIN-RELATED MYOTUBULARIN phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 organelle localization#GO:0051640;phosphatidylinositol dephosphorylation#GO:0046856;negative regulation of catabolic process#GO:0009895;dephosphorylation#GO:0016311;localization#GO:0051179;phospholipid dephosphorylation#GO:0046839;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;negative regulation of cellular process#GO:0048523;mitochondrion localization#GO:0051646;regulation of catabolic process#GO:0009894;cellular homeostasis#GO:0019725;negative regulation of autophagy#GO:0010507;lipid modification#GO:0030258;regulation of organelle assembly#GO:1902115;regulation of metabolic process#GO:0019222;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;regulation of autophagosome assembly#GO:2000785;regulation of organelle organization#GO:0033043;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;glycerolipid metabolic process#GO:0046486;metabolic process#GO:0008152;regulation of macroautophagy#GO:0016241;cellular process#GO:0009987;negative regulation of macroautophagy#GO:0016242;glycerophospholipid metabolic process#GO:0006650 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000006931.3|UniProtKB=G3QVK5 G3QVK5 SH3D21 PTHR14167:SF28 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN 21 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000041928.1|UniProtKB=A0A2I2ZQI8 A0A2I2ZQI8 ZNF211 PTHR23226:SF432 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012822.3|UniProtKB=G3RAN2 G3RAN2 NSUN4 PTHR22808:SF32 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 5-CYTOSINE RRNA METHYLTRANSFERASE NSUN4 catalytic activity, acting on a rRNA#GO:0140102;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 primary metabolic process#GO:0044238;mitochondrial large ribosomal subunit assembly#GO:1902775;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;macromolecule modification#GO:0043412;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;mitochondrial ribosome assembly#GO:0061668;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA modification#GO:1900864;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;RNA metabolic process#GO:0016070;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000004468.3|UniProtKB=A0A2I2YU14 A0A2I2YU14 BORA PTHR14728:SF2 PROTEIN AURORA BOREALIS PROTEIN AURORA BOREALIS enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 regulation of microtubule-based process#GO:0032886;regulation of mitotic spindle organization#GO:0060236;regulation of mitotic nuclear division#GO:0007088;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of mitotic cell cycle#GO:0007346;regulation of cellular component organization#GO:0051128;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of nuclear division#GO:0051783 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000000042.2|UniProtKB=G3QCU3 G3QCU3 PTHR16771:SF14 26 PROTEASOME COMPLEX SUBUNIT DSS1 PROTEIN SEM1, ISOFORM 2-RELATED nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;proteasome complex#GO:0000502;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular protein-containing complex#GO:0140535 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000022821.2|UniProtKB=G3SFU5 G3SFU5 LOC101130354 PTHR14614:SF149 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN FAM86 N-TERMINAL DOMAIN-CONTAINING PROTEIN protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012678.3|UniProtKB=G3RA96 G3RA96 LOC101149653 PTHR26453:SF87 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C8 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025045.2|UniProtKB=G3RMX0 G3RMX0 TRIM37 PTHR36754:SF2 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 ubiquitin protein ligase binding#GO:0031625;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;tumor necrosis factor receptor superfamily binding#GO:0032813;ubiquitin-like protein ligase binding#GO:0044389;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;signaling receptor binding#GO:0005102;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;cytokine receptor binding#GO:0005126;binding#GO:0005488 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000040688.1|UniProtKB=A0A2I2Z3K1 A0A2I2Z3K1 PTHR45813:SF13 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F5 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;carbohydrate homeostasis#GO:0033500;cellular response to stimulus#GO:0051716;signaling#GO:0023052;homeostatic process#GO:0042592;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;energy reserve metabolic process#GO:0006112;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of precursor metabolites and energy#GO:0006091;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;glucose homeostasis#GO:0042593;multicellular organismal-level homeostasis#GO:0048871;energy derivation by oxidation of organic compounds#GO:0015980 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000000729.3|UniProtKB=G3QEM1 G3QEM1 MDC1 PTHR23196:SF34 PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN MEDIATOR OF DNA DAMAGE CHECKPOINT PROTEIN 1 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;positive regulation of RNA metabolic process#GO:0051254;cellular response to stress#GO:0033554;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000014432.3|UniProtKB=G3RET1 G3RET1 FABP3 PTHR11955:SF61 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, HEART lipid binding#GO:0008289;fatty acid binding#GO:0005504;organic acid binding#GO:0043177;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406 macromolecule localization#GO:0033036;lipid transport#GO:0006869;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000043334.1|UniProtKB=A0A2I2Z403 A0A2I2Z403 PI15 PTHR10334:SF63 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 15 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008191.4|UniProtKB=G3QYT0 G3QYT0 FOCAD PTHR16212:SF4 FOCADHESIN FAMILY MEMBER FOCADHESIN GORGO|Ensembl=ENSGGOG00000024816.2|UniProtKB=G3SJ21 G3SJ21 PTHR15286:SF13 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 10 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007810.3|UniProtKB=G3QXS6 G3QXS6 SIGLEC15 PTHR46942:SF1 SIALIC ACID-BINDING IG-LIKE LECTIN 15 SIALIC ACID-BINDING IG-LIKE LECTIN 15 regulation of hemopoiesis#GO:1903706;regulation of tissue remodeling#GO:0034103;regulation of bone resorption#GO:0045124;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of multicellular organismal development#GO:2000026;regulation of actin filament-based process#GO:0032970;regulation of cell differentiation#GO:0045595;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of multicellular organismal process#GO:0051239;regulation of bone remodeling#GO:0046850;regulation of cell development#GO:0060284 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000003575.3|UniProtKB=G3QLY5 G3QLY5 CCL23 PTHR12015:SF157 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 23 G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379 cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;regulation of cellular process#GO:0050794;cell motility#GO:0048870;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cytokine-mediated signaling pathway#GO:0019221;cell chemotaxis#GO:0060326;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;regulation of cell motility#GO:2000145;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of cell migration#GO:0030335;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;cell migration#GO:0016477;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;positive regulation of locomotion#GO:0040017;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to peptide#GO:1901652;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to cytokine#GO:0034097;taxis#GO:0042330;response to chemical#GO:0042221;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;cell surface receptor signaling pathway#GO:0007166;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000015071.3|UniProtKB=G3RGG1 G3RGG1 DLC1 PTHR12659:SF2 RHO-TYPE GTPASE ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 7 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;actin filament-based process#GO:0030029;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794 membrane microdomain#GO:0098857;anchoring junction#GO:0070161;cell junction#GO:0030054;membrane#GO:0016020;membrane raft#GO:0045121;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000009467.3|UniProtKB=G3R211 G3R211 LOC101143316 PTHR21633:SF24 IQ MOTIF CONTAINING F IQ DOMAIN-CONTAINING PROTEIN F5 GORGO|Ensembl=ENSGGOG00000003328.3|UniProtKB=G3S371 G3S371 ASXL1 PTHR13578:SF19 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL1 protein binding#GO:0005515;chromatin binding#GO:0003682;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;PcG protein complex#GO:0031519;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000002313.3|UniProtKB=G3QIR8 G3QIR8 TPP2 PTHR43806:SF14 PEPTIDASE S8 TRIPEPTIDYL-PEPTIDASE 2 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000013084.3|UniProtKB=A0A2I2YBI8 A0A2I2YBI8 PBDC1 PTHR13410:SF9 PROTEIN PBDC1 PROTEIN PBDC1 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058 GORGO|Ensembl=ENSGGOG00000001738.3|UniProtKB=G3QH88 G3QH88 FLVCR1 PTHR10924:SF2 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED CHOLINE_ETHANOLAMINE TRANSPORTER FLVCR1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;heme binding#GO:0020037;binding#GO:0005488;tetrapyrrole binding#GO:0046906 cellular developmental process#GO:0048869;establishment of localization#GO:0051234;multicellular organismal-level homeostasis#GO:0048871;intracellular transport#GO:0046907;iron coordination entity transport#GO:1901678;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;anatomical structure development#GO:0048856;cellular localization#GO:0051641;erythrocyte differentiation#GO:0030218;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;immune system process#GO:0002376;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826;homeostasis of number of cells#GO:0048872;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;mitochondrial transport#GO:0006839;cell development#GO:0048468;metal ion transport#GO:0030001;homeostatic process#GO:0042592 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000003870.3|UniProtKB=G3QMQ1 G3QMQ1 RSPH3 PTHR21648:SF0 FLAGELLAR RADIAL SPOKE PROTEIN 3 RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000024992.2|UniProtKB=G3SEK0 G3SEK0 SLC16A7 PTHR11360:SF25 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 2 monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024016.2|UniProtKB=G3S5G8 G3S5G8 PTHR24055:SF423 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000001540.3|UniProtKB=G3QGQ9 G3QGQ9 ETV6 PTHR11849:SF19 ETS TRANSCRIPTION FACTOR ETV6 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000009810.3|UniProtKB=G3R2X2 G3R2X2 PPARGC1A PTHR15528:SF10 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;multicellular organismal-level homeostasis#GO:0048871;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000007878.4|UniProtKB=A0A2I2ZSQ1 A0A2I2ZSQ1 TFDP2 PTHR12548:SF5 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP-2 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000016235.3|UniProtKB=G3SAJ3 G3SAJ3 ITPR3 PTHR45816:SF1 MIR DOMAIN-CONTAINING PROTEIN INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR GORGO|Ensembl=ENSGGOG00000000477.3|UniProtKB=G3QDY9 G3QDY9 GON4L PTHR16088:SF3 YY1 ASSOCIATED PROTEIN-RELATED GON-4-LIKE PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000036742.1|UniProtKB=A0A2I2YNS7 A0A2I2YNS7 PTHR11960:SF38 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E FAMILY MEMBER 2 binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000007192.4|UniProtKB=G3QW93 G3QW93 CFAP74 PTHR22538:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74 GORGO|Ensembl=ENSGGOG00000044147.1|UniProtKB=A0A2I2YQY5 A0A2I2YQY5 PTHR13999:SF10 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 5 biomineral tissue development#GO:0031214;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;anatomical structure morphogenesis#GO:0009653;animal organ morphogenesis#GO:0009887;ossification#GO:0001503;developmental process#GO:0032502;bone mineralization#GO:0030282;animal organ development#GO:0048513;multicellular organism development#GO:0007275;bone development#GO:0060348;skeletal system morphogenesis#GO:0048705;tissue development#GO:0009888;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000016899.3|UniProtKB=G3RL52 G3RL52 TRIM17 PTHR24103:SF397 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM17 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to biotic stimulus#GO:0009607;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;immune system process#GO:0002376;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000016010.3|UniProtKB=G3RIV0 G3RIV0 PTHR14199:SF35 NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 6-LIKE PROTEIN NBPF FAMILY MEMBER NBPF1-RELATED GORGO|Ensembl=ENSGGOG00000001387.3|UniProtKB=G3QGB8 G3QGB8 PTHR38501:SF1 PHOTORECEPTOR DISK COMPONENT PRCD PHOTORECEPTOR DISK COMPONENT PRCD binding#GO:0005488;protein binding#GO:0005515 cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;plasma membrane region#GO:0098590 GORGO|Ensembl=ENSGGOG00000016700.3|UniProtKB=G3RN67 G3RN67 PLOD3 PTHR10730:SF7 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER MULTIFUNCTIONAL PROCOLLAGEN LYSINE HYDROXYLASE AND GLYCOSYLTRANSFERASE LH3 glucosyltransferase activity#GO:0046527;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006521.4|UniProtKB=A0A2I2YD74 A0A2I2YD74 WFDC8 PTHR47769:SF1 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 8 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 8 GORGO|Ensembl=ENSGGOG00000043147.1|UniProtKB=A0A2I2Y2J3 A0A2I2Y2J3 PTHR12498:SF0 N-TERMINAL ASPARAGINE AMIDOHYDROLASE PROTEIN N-TERMINAL ASPARAGINE AMIDOHYDROLASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000025198.2|UniProtKB=A0A2I2YYV4 A0A2I2YYV4 COCH PTHR24020:SF36 COLLAGEN ALPHA COCHLIN sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;system process#GO:0003008;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000001761.3|UniProtKB=G3QHA9 G3QHA9 LOC101148180 PTHR23226:SF430 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 1010-RELATED DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022642.2|UniProtKB=G3S5B6 G3S5B6 MANBAL PTHR14409:SF2 MANNOSIDASE, BETA A, LYSOSOMAL-LIKE, MANBAL PROTEIN PROTEIN MANBAL GORGO|Ensembl=ENSGGOG00000015434.3|UniProtKB=A0A2I2ZKU1 A0A2I2ZKU1 PTHR24112:SF50 LEUCINE-RICH REPEAT, ISOFORM F-RELATED RIBONUCLEASE INHIBITOR molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;regulation of multicellular organismal development#GO:2000026;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of angiogenesis#GO:0045765;cell migration#GO:0016477;regulation of actin cytoskeleton organization#GO:0032956;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of anatomical structure morphogenesis#GO:0022603;regulation of actin filament-based process#GO:0032970;regulation of vasculature development#GO:1901342;regulation of actin nucleation#GO:0051125 intracellular organelle lumen#GO:0070013;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;extracellular protein-containing complex#GO:0140392;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cell leading edge#GO:0031252;nucleus#GO:0005634;cell periphery#GO:0071944;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000025905.2|UniProtKB=G3SEF3 G3SEF3 ASCL4 PTHR13935:SF51 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 4 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000003914.3|UniProtKB=A0A2I2YX44 A0A2I2YX44 PDE10A PTHR11347:SF111 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP AND CAMP-INHIBITED CGMP 3',5'-CYCLIC PHOSPHODIESTERASE 10A cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 hydrolase#PC00121;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000005867.3|UniProtKB=G3QSU6 G3QSU6 EIF4A2 PTHR24031:SF762 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A-II primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;translational initiation#GO:0006413;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;cytoplasmic stress granule#GO:0010494;nucleus#GO:0005634;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000039420.1|UniProtKB=A0A2I2Y2F3 A0A2I2Y2F3 PTHR16716:SF2 CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL SUBFAMILY NOT NAMED transporter complex#GO:1990351;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739 oxidase#PC00175;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000036149.1|UniProtKB=A0A2I2Z7W2 A0A2I2Z7W2 TRIB2 PTHR22961:SF15 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 2 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488 positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000012144.3|UniProtKB=A0A2I2YRR9 A0A2I2YRR9 PTHR10827:SF75 RETICULOCALBIN RETICULOCALBIN-3 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000042209.1|UniProtKB=A0A2I2ZMR9 A0A2I2ZMR9 INHBA PTHR11848:SF133 TGF-BETA FAMILY INHIBIN BETA A CHAIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inhba#P06723;Gonadotropin-releasing hormone receptor pathway#P06664>Inhba/b#P06700;TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000006553.3|UniProtKB=A0A2I2Y469 A0A2I2Y469 EPB42 PTHR11590:SF44 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN 4.2 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000028488.2|UniProtKB=G3RS75 G3RS75 PTHR37553:SF10 DUF4705 DOMAIN-CONTAINING PROTEIN DUF4705 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000011110.3|UniProtKB=G3R687 G3R687 SARM1 PTHR22998:SF1 SARM1 NAD(+) HYDROLASE SARM1 catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 pyridine nucleotide catabolic process#GO:0019364;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleobase-containing compound metabolic process#GO:0006139;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166 intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cell body#GO:0044297;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;organelle#GO:0043226;neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003721.3|UniProtKB=G3QMB9 G3QMB9 TMEM89 PTHR37869:SF1 TRANSMEMBRANE PROTEIN 89 TRANSMEMBRANE PROTEIN 89 GORGO|Ensembl=ENSGGOG00000013794.3|UniProtKB=G3S807 G3S807 ST8SIA5 PTHR11987:SF4 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8E glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;oligosaccharide metabolic process#GO:0009311;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000008048.3|UniProtKB=G3QYD7 G3QYD7 PTHR22745:SF0 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000007200.3|UniProtKB=G3QWA2 G3QWA2 KIAA1549 PTHR21590:SF4 SEA DOMAIN-CONTAINING PROTEIN UPF0606 PROTEIN KIAA1549 GORGO|Ensembl=ENSGGOG00000008949.3|UniProtKB=G3R0Q5 G3R0Q5 IL22 PTHR48488:SF1 INTERLEUKIN-22 INTERLEUKIN-22 cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002139.3|UniProtKB=G3SJF1 G3SJF1 TSC1 PTHR15154:SF2 HAMARTIN HAMARTIN regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of TOR signaling#GO:0032006;negative regulation of cell population proliferation#GO:0008285;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of cell population proliferation#GO:0042127;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC1#P04495;p53 pathway by glucose deprivation#P04397>TSC1#P04645 GORGO|Ensembl=ENSGGOG00000004588.3|UniProtKB=G3QPJ8 G3QPJ8 TXNDC15 PTHR14684:SF2 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000013750.3|UniProtKB=G3S1L9 G3S1L9 PTHR13857:SF20 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3G hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cytidine to uridine editing#GO:0016554;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to external biotic stimulus#GO:0043207;response to virus#GO:0009615;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;defense response#GO:0006952;response to external stimulus#GO:0009605;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;biological process involved in interspecies interaction between organisms#GO:0044419;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;base conversion or substitution editing#GO:0016553;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000005071.3|UniProtKB=G3QQU8 G3QQU8 RAPGEFL1 PTHR23113:SF230 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR-LIKE 1 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000037970.1|UniProtKB=A0A2I2Y397 A0A2I2Y397 RGS8 PTHR10845:SF147 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 8 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 GORGO|Ensembl=ENSGGOG00000040471.1|UniProtKB=A0A2I2Y4A1 A0A2I2Y4A1 SYNRG PTHR15463:SF2 AP1 GAMMA SUBUNIT BINDING PROTEIN 1 SYNERGIN GAMMA clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle coat#GO:0030120;intracellular organelle#GO:0043229;coated membrane#GO:0048475;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;clathrin-coated vesicle#GO:0030136;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;trans-Golgi network transport vesicle#GO:0030140;membrane coat#GO:0030117;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000015945.3|UniProtKB=G3RIQ1 G3RIQ1 SYNJ1 PTHR11200:SF158 INOSITOL 5-PHOSPHATASE POLYPHOSPHATIDYLINOSITOL PHOSPHATASE SYNJ1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 synaptic vesicle cycle#GO:0099504;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle endocytosis#GO:0048488;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 membrane#GO:0016020;presynapse#GO:0098793;cellular anatomical structure#GO:0110165;synapse#GO:0045202;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 Huntington disease#P00029>Synaptojanin#P00804 GORGO|Ensembl=ENSGGOG00000013625.3|UniProtKB=G3QFY0 G3QFY0 LOC101141395 PTHR19944:SF64 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DP ALPHA 1 CHAIN antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488;protein-containing complex binding#GO:0044877 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cell adhesion#GO:0045785;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882 vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 GORGO|Ensembl=ENSGGOG00000006926.3|UniProtKB=G3QVK0 G3QVK0 STARD9 PTHR47117:SF1 STAR-RELATED LIPID TRANSFER PROTEIN 9 STAR-RELATED LIPID TRANSFER PROTEIN 9 catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630 GORGO|Gene=NDUFB9|UniProtKB=Q0MQE9 Q0MQE9 NDUFB9 PTHR12868:SF1 NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016127.3|UniProtKB=G3RJ61 G3RJ61 ADAMTS6 PTHR13723:SF27 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 6 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000022170.2|UniProtKB=G3SAP6 G3SAP6 LOC101136040 PTHR26453:SF626 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016996.3|UniProtKB=G3RLE1 G3RLE1 CAPZA3 PTHR10653:SF6 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-3 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of protein depolymerization#GO:1901879;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament organization#GO:0110053;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein-containing complex assembly#GO:0031333;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000026392.2|UniProtKB=G3S6A0 G3S6A0 ZNF624 PTHR23226:SF412 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002667.3|UniProtKB=G3QJN2 G3QJN2 SLC17A5 PTHR11662:SF432 SOLUTE CARRIER FAMILY 17 SIALIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate derivative transmembrane transporter activity#GO:1901505 transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;localization#GO:0051179;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;plasma membrane region#GO:0098590;apical part of cell#GO:0045177;lytic vacuole#GO:0000323;lysosome#GO:0005764;apical plasma membrane#GO:0016324;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000011003.3|UniProtKB=G3R5Z3 G3R5Z3 ELP6 PTHR16184:SF6 ELONGATOR COMPLEX PROTEIN 6 ELONGATOR COMPLEX PROTEIN 6 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;elongator holoenzyme complex#GO:0033588;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000005414.3|UniProtKB=G3RN98 G3RN98 DDX39A PTHR47958:SF10 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX39A nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098 mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;RNA biosynthetic process#GO:0032774;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA splicing, via transesterification reactions#GO:0000375;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000026799.2|UniProtKB=G3RXG3 G3RXG3 GARIN1A PTHR22574:SF10 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 1A GORGO|Ensembl=ENSGGOG00000006845.3|UniProtKB=G3SBX7 G3SBX7 PTHR23235:SF59 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 14 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 GORGO|Gene=FOXP2|UniProtKB=Q8MJ99 Q8MJ99 FOXP2 PTHR45796:SF1 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;skeletal muscle tissue development#GO:0007519;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;muscle organ development#GO:0007517 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000008817.3|UniProtKB=G3R0D2 G3R0D2 KCNJ13 PTHR11767:SF3 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 13 voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000034936.2|UniProtKB=G3SKW0 G3SKW0 PTHR10098:SF108 RAPSYN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 28 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016464.3|UniProtKB=G3RK03 G3RK03 ATOH7 PTHR19290:SF99 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH7 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cell fate commitment#GO:0045165;neuron development#GO:0048666;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron fate commitment#GO:0048663;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000006320.3|UniProtKB=Q0MQC2 Q0MQC2 NDUFAB1 PTHR20863:SF80 ACYL CARRIER PROTEIN ACYL CARRIER PROTEIN, MITOCHONDRIAL molecular carrier activity#GO:0140104;small molecule binding#GO:0036094;binding#GO:0005488 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000043309.1|UniProtKB=A0A2I2ZU32 A0A2I2ZU32 PTHR31368:SF7 DEVELOPMENT PLURPOTENCY-ASSOCIATED PROTEIN 1/5 FAMILY MEMBER KH-LIKE RNA-BINDING DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016911.3|UniProtKB=G3RL67 G3RL67 TGFBR2 PTHR23255:SF55 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-2 signaling receptor binding#GO:0005102;molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transforming growth factor beta binding#GO:0050431;cytokine binding#GO:0019955;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;activin binding#GO:0048185;transforming growth factor beta receptor activity#GO:0005024;transferase activity#GO:0016740;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;response to growth factor#GO:0070848;response to stimulus#GO:0050896;activin receptor signaling pathway#GO:0032924;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;transferase complex#GO:1990234;catalytic complex#GO:1902494;signaling receptor complex#GO:0043235;transferase complex, transferring phosphorus-containing groups#GO:0061695 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 GORGO|Ensembl=ENSGGOG00000015399.3|UniProtKB=G3RHA5 G3RHA5 YIPF1 PTHR12822:SF4 PROTEIN YIPF PROTEIN YIPF1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000034826.2|UniProtKB=A0A2I2ZTE0 A0A2I2ZTE0 PTHR14927:SF0 NUCLEOLAR PROTEIN 10 NUCLEOLAR PROTEIN 10 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000000391.3|UniProtKB=G3QDQ9 G3QDQ9 ILK PTHR23257:SF992 SERINE-THREONINE PROTEIN KINASE SCAFFOLD PROTEIN ILK transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007384.3|UniProtKB=G3QWR5 G3QWR5 FAM135B PTHR12482:SF3 LIPASE ROG1-RELATED-RELATED PROTEIN FAM135B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 GORGO|Ensembl=ENSGGOG00000009454.3|UniProtKB=G3R202 G3R202 PPP1R36 PTHR21055:SF3 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000005722.3|UniProtKB=G3QSH1 G3QSH1 ITIH1 PTHR10338:SF106 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H1 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000013981.3|UniProtKB=G3RDM9 G3RDM9 RBM45 PTHR24012:SF812 RNA BINDING PROTEIN RNA-BINDING PROTEIN 45 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000011767.3|UniProtKB=G3R7X8 G3R7X8 SPMIP9 PTHR36882:SF1 TESTIS-EXPRESSED SEQUENCE 37 PROTEIN PROTEIN SPMIP9 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000036853.1|UniProtKB=A0A2I2Y6N6 A0A2I2Y6N6 EPN1 PTHR12276:SF48 EPSIN/ENT-RELATED EPSIN-1 binding#GO:0005488;phospholipid binding#GO:0005543;clathrin binding#GO:0030276;protein binding#GO:0005515;lipid binding#GO:0008289 transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;endosome#GO:0005768;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle#GO:0030136;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane#GO:0005886;vesicle coat#GO:0030120;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011920.3|UniProtKB=A0A2I2ZWJ6 A0A2I2ZWJ6 OSTF1 PTHR24155:SF10 OSTEOCLAST-STIMULATING FACTOR 1 OSTEOCLAST-STIMULATING FACTOR 1 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 GORGO|Ensembl=ENSGGOG00000005681.3|UniProtKB=A0A2I2ZNL7 A0A2I2ZNL7 PSMG1 PTHR15069:SF1 PROTEASOME ASSEMBLY CHAPERONE 1 PROTEASOME ASSEMBLY CHAPERONE 1 binding#GO:0005488;protein-containing complex binding#GO:0044877 chaperone-mediated protein complex assembly#GO:0051131;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein folding chaperone complex#GO:0101031;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000038135.1|UniProtKB=A0A2I2ZCX3 A0A2I2ZCX3 PTHR21500:SF2 TUBULIN-SPECIFIC CHAPERONE A TUBULIN-SPECIFIC CHAPERONE A cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000007901.3|UniProtKB=G3RU10 G3RU10 METTL26 PTHR20974:SF2 UPF0585 PROTEIN CG18661 METHYLTRANSFERASE-LIKE 26 GORGO|Ensembl=ENSGGOG00000036322.1|UniProtKB=A0A2I2ZJN8 A0A2I2ZJN8 PTHR33888:SF1 RIKEN CDNA 4932415D10 GENE SPERMATOGENESIS-ASSOCIATED PROTEIN 31H1 GORGO|Ensembl=ENSGGOG00000013504.3|UniProtKB=A0A2I2ZDA0 A0A2I2ZDA0 CFAP263 PTHR15654:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 263 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014 GORGO|Ensembl=ENSGGOG00000006128.3|UniProtKB=A0A2I2Y5J5 A0A2I2Y5J5 PPP1R14A PTHR16188:SF4 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14A phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein serine/threonine phosphatase inhibitor activity#GO:0004865 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000036584.1|UniProtKB=A0A2I2Z2V2 A0A2I2Z2V2 LYRM2 PTHR13675:SF2 LYR MOTIF-CONTAINING PROTEIN 2 LYR MOTIF-CONTAINING PROTEIN 2 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016546.3|UniProtKB=A0A2I2Y7K9 A0A2I2Y7K9 SERPINB6 PTHR11461:SF204 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B6 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000026443.2|UniProtKB=G3S730 G3S730 ABCC10 PTHR24223:SF330 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 10 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;xenobiotic transmembrane transporter activity#GO:0042910;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000016347.3|UniProtKB=A0A2I2Z587 A0A2I2Z587 ARSL PTHR42693:SF48 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE L hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000002250.3|UniProtKB=G3QIK2 G3QIK2 PTHR13379:SF0 UNCHARACTERIZED DUF1308 UPF0415 PROTEIN C7ORF25 GORGO|Ensembl=ENSGGOG00000002182.3|UniProtKB=G3QIE1 G3QIE1 SPIRE2 PTHR21345:SF5 SPIRE PROTEIN SPIRE HOMOLOG 2 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 gamete generation#GO:0007276;establishment of organelle localization#GO:0051656;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cellular localization#GO:0051641;spindle localization#GO:0051653;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;nuclear division#GO:0000280;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;membrane invagination#GO:0010324;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;actin cytoskeleton organization#GO:0030036;cell division#GO:0051301;cell cycle#GO:0007049;multicellular organismal reproductive process#GO:0048609;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;actin filament-based process#GO:0030029;sexual reproduction#GO:0019953;organelle localization#GO:0051640;membrane organization#GO:0061024;establishment of spindle localization#GO:0051293;actin filament organization#GO:0007015;meiotic nuclear division#GO:0140013;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;cell cortex#GO:0005938;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000040622.1|UniProtKB=A0A2I2Z658 A0A2I2Z658 PTHR12789:SF0 DENSITY-REGULATED PROTEIN HOMOLOG DENSITY-REGULATED PROTEIN ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000041515.1|UniProtKB=A0A2I2YKX6 A0A2I2YKX6 NECTIN1 PTHR23277:SF69 NECTIN-RELATED NECTIN-1 protein binding#GO:0005515;virus receptor activity#GO:0001618;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488 cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;macromolecule localization#GO:0033036;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;intracellular protein localization#GO:0008104;localization#GO:0051179;cell adhesion#GO:0007155;protein localization to cell junction#GO:1902414 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;apical junction complex#GO:0043296 cell adhesion molecule#PC00069 Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha#P00160;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha N-terminal fragment#P00164;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha C-terminal fragment#P00177;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha transmembrane fragment#P00134;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha intracellular fragment#P00159 GORGO|Ensembl=ENSGGOG00000022749.2|UniProtKB=G3RUK0 G3RUK0 PTHR11875:SF145 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 1 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000869.3|UniProtKB=G3QEZ8 G3QEZ8 GOLPH3L PTHR12704:SF4 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3-LIKE molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;cargo adaptor activity#GO:0140312 Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;protein localization to cell periphery#GO:1990778;transport#GO:0006810;Golgi vesicle transport#GO:0048193 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytosol#GO:0005829;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000024697.2|UniProtKB=G3S679 G3S679 FAHD1 PTHR11820:SF106 ACYLPYRUVASE OXALOACETATE TAUTOMERASE FAHD1, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000009540.3|UniProtKB=G3R286 G3R286 USP47 PTHR24006:SF702 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 47 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000026823.2|UniProtKB=G3RW70 G3RW70 PTHR37366:SF1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 6 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 6 fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;cellular process#GO:0009987;single fertilization#GO:0007338;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;fertilization#GO:0009566;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609 GORGO|Ensembl=ENSGGOG00000040945.1|UniProtKB=A0A2I2ZUC8 A0A2I2ZUC8 PTHR12984:SF17 SCY1-RELATED S/T PROTEIN KINASE-LIKE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000036717.1|UniProtKB=A0A2I2ZI14 A0A2I2ZI14 SHISA9 PTHR31774:SF1 PROTEIN SHISA-9-RELATED PROTEIN SHISA-9 regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of neuronal synaptic plasticity#GO:0048168;regulation of signaling#GO:0023051;regulation of synaptic plasticity#GO:0048167 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;dendrite#GO:0030425;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;leading edge membrane#GO:0031256;postsynaptic membrane#GO:0045211;cell projection membrane#GO:0031253;neuron projection#GO:0043005;cell leading edge#GO:0031252;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351 GORGO|Ensembl=ENSGGOG00000012412.3|UniProtKB=G3R9M5 G3R9M5 ACP5 PTHR10161:SF68 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 iron ion binding#GO:0005506;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;acid phosphatase activity#GO:0003993;catalytic activity#GO:0003824;ferrous iron binding#GO:0008198;cation binding#GO:0043169;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 bone resorption#GO:0045453;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;tissue remodeling#GO:0048771;homeostatic process#GO:0042592;bone remodeling#GO:0046849 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010365.3|UniProtKB=G3R4B5 G3R4B5 ISG20 PTHR12801:SF59 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED INTERFERON-STIMULATED GENE 20 KDA PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;DNA catabolic process#GO:0006308;RNA metabolic process#GO:0016070;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to external biotic stimulus#GO:0043207;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;response to virus#GO:0009615;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;response to other organism#GO:0051707;response to external stimulus#GO:0009605;defense response#GO:0006952;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 exoribonuclease#PC00099;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004730.3|UniProtKB=G3QPY2 G3QPY2 LOC101146993 PTHR13944:SF23 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 18 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000017154.3|UniProtKB=G3RPB8 G3RPB8 LOC101142845 PTHR43880:SF73 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE 1A oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;metal ion binding#GO:0046872;cation binding#GO:0043169;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;ion binding#GO:0043167;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cellular response to oxygen-containing compound#GO:1901701;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;olefinic compound metabolic process#GO:0120254;regulation of biological quality#GO:0065008;regulation of hormone levels#GO:0010817;monocarboxylic acid metabolic process#GO:0032787;cellular detoxification of aldehyde#GO:0110095;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;lipid metabolic process#GO:0006629;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;biological regulation#GO:0065007;aldehyde catabolic process#GO:0046185;hormone metabolic process#GO:0042445;terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;isoprenoid metabolic process#GO:0006720;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to toxic substance#GO:0009636 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000000848.3|UniProtKB=G3QEX8 G3QEX8 OAT PTHR11986:SF118 AMINOTRANSFERASE CLASS III ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000042426.1|UniProtKB=A0A2I2ZF41 A0A2I2ZF41 PTHR21528:SF3 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;organophosphate metabolic process#GO:0019637;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000038776.1|UniProtKB=G3RVA7 G3RVA7 LOC109025132 PTHR23331:SF5 CXYORF1 WAS PROTEIN FAMILY HOMOLOG 2-RELATED cellular component organization#GO:0016043;export from cell#GO:0140352;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;localization within membrane#GO:0051668;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;secretion by cell#GO:0032940;localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;establishment of localization in cell#GO:0051649;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;exocytosis#GO:0006887;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229;recycling endosome#GO:0055037 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000004837.3|UniProtKB=G3QQ81 G3QQ81 NAGPA PTHR40446:SF2 N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE transport#GO:0006810;protein secretion#GO:0009306;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;export from cell#GO:0140352 GORGO|Ensembl=ENSGGOG00000040910.1|UniProtKB=G3SGK5 G3SGK5 TMX4 PTHR46107:SF1 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 4 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010518.3|UniProtKB=G3R4P6 G3R4P6 LOC101145923 PTHR26453:SF626 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007566.3|UniProtKB=G3QX70 G3QX70 GLRX5 PTHR10293:SF16 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000041613.1|UniProtKB=A0A2I2Z952 A0A2I2Z952 ARL17A PTHR11711:SF486 ADP RIBOSYLATION FACTOR-RELATED SUBFAMILY NOT NAMED nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000010047.3|UniProtKB=G3R3H9 G3R3H9 LOC101151536 PTHR10707:SF12 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 1, MITOCHONDRIAL ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;transporter complex#GO:1990351;organelle membrane#GO:0031090;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000024119.2|UniProtKB=G3S953 G3S953 CLEC6A PTHR22802:SF249 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 6 MEMBER A carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to fungus#GO:0050832;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000014285.3|UniProtKB=G3REF5 G3REF5 PYGB PTHR11468:SF29 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, BRAIN FORM glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 cellular process#GO:0009987;glycogen catabolic process#GO:0005980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;polysaccharide catabolic process#GO:0000272;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;energy reserve metabolic process#GO:0006112;carbohydrate catabolic process#GO:0016052 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transferase#PC00220;glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718 GORGO|Ensembl=ENSGGOG00000027325.2|UniProtKB=G3S812 G3S812 PTHR24409:SF330 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 521 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015384.3|UniProtKB=G3RH90 G3RH90 PDE6G PTHR12122:SF4 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED ROD CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 ciliary membrane#GO:0060170;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;cilium#GO:0005929 phosphodiesterase#PC00185 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEgamma#P00754 GORGO|Ensembl=ENSGGOG00000034810.2|UniProtKB=G3SKF7 G3SKF7 KIF2C PTHR24115:SF454 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2C hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;microtubule-based movement#GO:0007018;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000011586.3|UniProtKB=A0A2I2YD97 A0A2I2YD97 WT1 PTHR23235:SF49 KRUEPPEL-LIKE TRANSCRIPTION FACTOR WILMS TUMOR PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013663.3|UniProtKB=G3RCU3 G3RCU3 IFI44 PTHR14241:SF3 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 GORGO|Ensembl=ENSGGOG00000002391.3|UniProtKB=G3QIY2 G3QIY2 NR0B1 PTHR24081:SF10 NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B MEMBER 1 transcription coregulator activity#GO:0003712;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription regulator activity#GO:0140110;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297 sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;reproductive system development#GO:0061458;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;development of primary male sexual characteristics#GO:0046546;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;spermatogenesis#GO:0007283;male sex differentiation#GO:0046661;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;male gamete generation#GO:0048232;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;gonad development#GO:0008406;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;reproductive structure development#GO:0048608;development of primary sexual characteristics#GO:0045137;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of macromolecule biosynthetic process#GO:0010558;male gonad development#GO:0008584;sex differentiation#GO:0007548 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000023894.2|UniProtKB=G3S1M6 G3S1M6 ZSCAN26 PTHR23226:SF56 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 26 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004590.3|UniProtKB=A0A2I2Z314 A0A2I2Z314 ACOX1 PTHR10909:SF397 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 1 anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;lipid binding#GO:0008289;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000013386.3|UniProtKB=G3RC34 G3RC34 IDI2 PTHR10885:SF1 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE 2 isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;metabolic process#GO:0008152;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 isomerase#PC00135 Cholesterol biosynthesis#P00014>Isopentenyl diphosphate delta-isomerase#P00495 GORGO|Ensembl=ENSGGOG00000007811.3|UniProtKB=G3QXT5 G3QXT5 GIGYF2 PTHR14445:SF38 GRB10 INTERACTING GYF PROTEIN GRB10-INTERACTING GYF PROTEIN 2 translation regulator activity#GO:0045182 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;insulin-like growth factor receptor signaling pathway#GO:0048009;response to stimulus#GO:0050896;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297;vesicle#GO:0031982;perikaryon#GO:0043204;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;neuron projection#GO:0043005 GORGO|Ensembl=ENSGGOG00000004830.3|UniProtKB=A0A2I2Y2G4 A0A2I2Y2G4 TANGO2 PTHR17985:SF28 SER/THR-RICH PROTEIN T10 IN DGCR REGION TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;transport#GO:0006810;endomembrane system organization#GO:0010256;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;protein secretion#GO:0009306;secretion#GO:0046903;secretion by cell#GO:0032940;protein transport#GO:0015031;export from cell#GO:0140352;cellular component organization#GO:0016043;Golgi organization#GO:0007030;protein localization to extracellular region#GO:0071692 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000036849.1|UniProtKB=G3R2I8 G3R2I8 PTHR12815:SF18 SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594 mitochondrial outer membrane translocase complex#GO:0005742;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000014475.3|UniProtKB=A0A2I2Y610 A0A2I2Y610 DOK3 PTHR21258:SF42 DOCKING PROTEIN RELATED DOCKING PROTEIN 3 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dok-R#P00180 GORGO|Ensembl=ENSGGOG00000002575.3|UniProtKB=G3QJE0 G3QJE0 SMIM8 PTHR14274:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 8 SMALL INTEGRAL MEMBRANE PROTEIN 8 GORGO|Ensembl=ENSGGOG00000015818.3|UniProtKB=A0A2I2Z9E4 A0A2I2Z9E4 SP7 PTHR23235:SF19 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP7 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024329.2|UniProtKB=A0A2I2ZTV2 A0A2I2ZTV2 SSR4 PTHR12731:SF1 TRANSLOCON-ASSOCIATED PROTEIN, DELTA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT DELTA endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000025405.2|UniProtKB=G3RR03 G3RR03 LOC101133285 PTHR11504:SF4 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT 6A1, MITOCHONDRIAL enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000036508.1|UniProtKB=G3R849 G3R849 LOC101150014 PTHR26453:SF23 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026422.2|UniProtKB=A0A2I2Y587 A0A2I2Y587 PDE4A PTHR11347:SF74 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4A hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000005365.3|UniProtKB=G3QRJ6 G3QRJ6 CD200R1 PTHR21462:SF4 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;regulation of immune system process#GO:0002682;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of response to stress#GO:0080134;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005991.3|UniProtKB=A0A2I2Z2F0 A0A2I2Z2F0 INPP5F PTHR45662:SF8 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITIDE 4-PHOSPHATASE SAC2 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;lipid modification#GO:0030258;regulation of transport#GO:0051049;regulation of localization#GO:0032879;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid dephosphorylation#GO:0046839;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;phosphatidylinositol dephosphorylation#GO:0046856;dephosphorylation#GO:0016311 endomembrane system#GO:0012505;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endoplasmic reticulum#GO:0005783;clathrin-coated endocytic vesicle#GO:0045334;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endocytic vesicle#GO:0030139;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000008163.3|UniProtKB=G3QYN8 G3QYN8 POGK PTHR19303:SF57 TRANSPOSON POGO TRANSPOSABLE ELEMENT WITH KRAB DOMAIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000040796.1|UniProtKB=G3SDY4 G3SDY4 PTHR12928:SF4 FRG1 PROTEIN FRG1 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000008927.3|UniProtKB=G3RQF1 G3RQF1 DAAM2 PTHR45725:SF7 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 2 regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;regulation of nervous system development#GO:0051960;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cell development#GO:0060284;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of multicellular organismal process#GO:0051239;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;positive regulation of canonical Wnt signaling pathway#GO:0090263 GORGO|Ensembl=ENSGGOG00000009624.3|UniProtKB=A0A2I2YF76 A0A2I2YF76 PTHR20648:SF13 ELONGIN-C ELONGIN-C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000023499.2|UniProtKB=A0A2I2Z9P9 A0A2I2Z9P9 PTHR20982:SF11 RIBOSOME RECYCLING FACTOR SUBFAMILY NOT NAMED ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 protein-containing complex disassembly#GO:0032984;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mitochondrial gene expression#GO:0140053;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;translation#GO:0006412;translational termination#GO:0006415;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translation release factor#PC00225 GORGO|Ensembl=ENSGGOG00000004211.3|UniProtKB=G3QNL4 G3QNL4 GPAT3 PTHR23063:SF10 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 3 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000147.3|UniProtKB=G3QD42 G3QD42 CLRN1 PTHR31548:SF4 CLARIN CLARIN-1 nervous system process#GO:0050877;sensory perception#GO:0007600;neuromuscular process#GO:0050905;sensory perception of mechanical stimulus#GO:0050954;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;system process#GO:0003008 GORGO|Ensembl=ENSGGOG00000015917.3|UniProtKB=G3RIL8 G3RIL8 FSTL3 PTHR13866:SF29 SPARC OSTEONECTIN FOLLISTATIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000001885.3|UniProtKB=G3QHM5 G3QHM5 FBXO10 PTHR22990:SF33 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 10 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000003115.3|UniProtKB=G3QKS8 G3QKS8 PRSS45P PTHR24253:SF74 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011830.3|UniProtKB=A0A2I2YG64 A0A2I2YG64 QTRT2 PTHR46064:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000011427.3|UniProtKB=G3R716 G3R716 TIMM17B PTHR10485:SF2 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-B transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transmembrane protein transporter activity#GO:0008320 establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016251.3|UniProtKB=G3RJG3 G3RJG3 MLANA PTHR15305:SF0 MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;melanosome#GO:0042470;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000028113.2|UniProtKB=A0A2I2ZUL5 A0A2I2ZUL5 PTHR13386:SF2 HISTONE PARYLATION FACTOR 1 HISTONE PARYLATION FACTOR 1 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000005597.3|UniProtKB=A0A2I2Y5H2 A0A2I2Y5H2 GPR156 PTHR10519:SF80 GABA-B RECEPTOR G PROTEIN-COUPLED RECEPTOR 156-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;cell communication#GO:0007154 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007256.3|UniProtKB=A0A2I2YJI5 A0A2I2YJI5 RGS6 PTHR45746:SF2 LP21163P REGULATOR OF G PROTEIN SIGNALING 6 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 neuron projection#GO:0043005;cell projection#GO:0042995;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 GORGO|Ensembl=ENSGGOG00000016752.3|UniProtKB=G3RKR3 G3RKR3 CCDC82 PTHR14689:SF0 PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 82 GORGO|Ensembl=ENSGGOG00000026494.2|UniProtKB=G3S9R1 G3S9R1 NKX2-1 PTHR24340:SF40 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.4 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000003408.3|UniProtKB=G3QLJ0 G3QLJ0 KLF1 PTHR23235:SF133 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000040625.1|UniProtKB=A0A2I2Y364 A0A2I2Y364 CEND1 PTHR36683:SF1 CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1 CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1 neurogenesis#GO:0022008;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;neuron differentiation#GO:0030182;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;head development#GO:0060322;nervous system development#GO:0007399;developmental maturation#GO:0021700;brain development#GO:0007420;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cellular process#GO:0009987;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell motility#GO:0048870;anatomical structure maturation#GO:0071695;anatomical structure morphogenesis#GO:0009653 GORGO|Ensembl=ENSGGOG00000000363.3|UniProtKB=A0A2I2Y4L6 A0A2I2Y4L6 MAJIN PTHR35824:SF1 MEMBRANE-ANCHORED JUNCTION PROTEIN MAJIN MEMBRANE-ANCHORED JUNCTION PROTEIN telomere localization#GO:0034397;cell cycle#GO:0007049;meiosis I#GO:0007127;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;telomere tethering at nuclear periphery#GO:0034398;nuclear division#GO:0000280;organelle localization#GO:0051640;sexual reproduction#GO:0019953;localization#GO:0051179;organelle fission#GO:0048285;organelle organization#GO:0006996;cellular process#GO:0009987;homologous chromosome pairing at meiosis#GO:0007129;chromosome localization#GO:0050000;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane#GO:0016020;nucleus#GO:0005634;organelle inner membrane#GO:0019866;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000005314.3|UniProtKB=G3QRF0 G3QRF0 LOC101137288 PTHR26453:SF91 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2M4 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009024.3|UniProtKB=G3R0Y0 G3R0Y0 DNAAF3 PTHR22118:SF14 DYNEIN ASSEMBLY FACTOR 3, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 3 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;organelle assembly#GO:0070925;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000005667.3|UniProtKB=Q9N297 Q9N297 HTR1A PTHR24247:SF20 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1A molecular transducer activity#GO:0060089;cation binding#GO:0043169;serotonin binding#GO:0051378;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;heterocyclic compound binding#GO:1901363;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227 chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 GORGO|Ensembl=ENSGGOG00000023417.2|UniProtKB=G3RVK0 G3RVK0 TOPORS PTHR46077:SF2 E3 UBIQUITIN-PROTEIN LIGASE TOPORS E3 UBIQUITIN-PROTEIN LIGASE TOPORS ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein sumoylation#GO:0016925;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;intracellular organelle lumen#GO:0070013;ciliary transition zone#GO:0035869;intracellular organelle#GO:0043229;cilium#GO:0005929;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;microtubule cytoskeleton#GO:0015630;9+0 non-motile cilium#GO:0097731;membrane-enclosed lumen#GO:0031974;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;nucleus#GO:0005634;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000010071.3|UniProtKB=G3R3J9 G3R3J9 SMNDC1 PTHR13681:SF26 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000006913.3|UniProtKB=A0A2I2Z2B1 A0A2I2Z2B1 HEATR1 PTHR13457:SF1 BAP28 HEAT REPEAT-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;RNA binding#GO:0003723 gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase I#GO:0045943;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;rRNA processing#GO:0006364;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase I#GO:0006356 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;small-subunit processome#GO:0032040;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000011385.3|UniProtKB=G3R6X7 G3R6X7 LMO1 PTHR45787:SF2 LD11652P RHOMBOTIN-1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000001232.3|UniProtKB=G3RS97 G3RS97 BCL11B PTHR45993:SF4 B-CELL LYMPHOMA/LEUKEMIA 11 B-CELL LYMPHOMA_LEUKEMIA 11B transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000038274.1|UniProtKB=A0A2I2Z2Q6 A0A2I2Z2Q6 PTHR24180:SF39 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 kinase modulator#PC00140;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000037752.1|UniProtKB=A0A2I2ZID7 A0A2I2ZID7 RMDN2 PTHR16056:SF15 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 2 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;mitochondrion#GO:0005739;spindle pole#GO:0000922;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle#GO:0005819;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000024765.2|UniProtKB=G3RQA3 G3RQA3 LOC101150079 PTHR15898:SF21 BIFUNCTIONAL APOPTOSIS REGULATOR BIFUNCTIONAL APOPTOSIS REGULATOR catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 GORGO|Ensembl=ENSGGOG00000005871.3|UniProtKB=G3QSV1 G3QSV1 COMTD1 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000023651.2|UniProtKB=A0A2I2ZSM2 A0A2I2ZSM2 TMEM230 PTHR15664:SF27 C20ORF30 PROTEIN TRANSMEMBRANE PROTEIN 230 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;establishment of organelle localization#GO:0051656;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory vesicle#GO:0099503;presynapse#GO:0098793;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000001836.3|UniProtKB=G3QHI1 G3QHI1 POU4F2 PTHR11636:SF41 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000025788.2|UniProtKB=G3SBC1 G3SBC1 LALBA PTHR11407:SF32 LYSOZYME C ALPHA-LACTALBUMIN hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000015830.3|UniProtKB=G3RIE0 G3RIE0 KLC3 PTHR45783:SF1 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 3 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 GORGO|Ensembl=ENSGGOG00000013484.3|UniProtKB=G3RCC8 G3RCC8 FAM50A PTHR12722:SF2 XAP-5 PROTEIN-RELATED PROTEIN FAM50A cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000013569.3|UniProtKB=G3RCL0 G3RCL0 UTP6 PTHR23271:SF3 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462 90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012596.3|UniProtKB=G3RA28 G3RA28 BPHL PTHR46331:SF2 VALACYCLOVIR HYDROLASE SERINE HYDROLASE BPHL serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000009300.3|UniProtKB=G3R1K7 G3R1K7 PTHR16433:SF0 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;mannosyltransferase complex#GO:0031501;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000008250.3|UniProtKB=G3QYX0 G3QYX0 SH3RF2 PTHR14167:SF60 SH3 DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE SH3RF2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;protein phosphatase binding#GO:0019903;molecular adaptor activity#GO:0060090;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein-macromolecule adaptor activity#GO:0030674;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025636.2|UniProtKB=G3S020 G3S020 PCMTD1 PTHR11579:SF4 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000005509.3|UniProtKB=G3QRY2 G3QRY2 STK11IP PTHR15454:SF75 NISCHARIN RELATED SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000023193.2|UniProtKB=G3SC70 G3SC70 LOC101130608 PTHR24068:SF572 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBC12 ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000004293.3|UniProtKB=G3QNT3 G3QNT3 CHP2 PTHR46002:SF6 EG:114D9.1 PROTEIN-RELATED CALCINEURIN B HOMOLOGOUS PROTEIN 2 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 regulation of calcineurin-NFAT signaling cascade#GO:0070884;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;positive regulation of calcium-mediated signaling#GO:0050850;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000023355.2|UniProtKB=G3RZT1 G3RZT1 RNF224 PTHR47454:SF1 RING FINGER PROTEIN 224 RING FINGER PROTEIN 224 GORGO|Ensembl=ENSGGOG00000015912.3|UniProtKB=G3RIL5 G3RIL5 RNF126 PTHR15710:SF21 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF126 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;cellular response to topologically incorrect protein#GO:0035967;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;response to topologically incorrect protein#GO:0035966;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to misfolded protein#GO:0071218;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000006555.3|UniProtKB=G3QUL1 G3QUL1 TGM5 PTHR11590:SF38 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 5 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004108.3|UniProtKB=A0A2I2Y2M7 A0A2I2Y2M7 BRWD3 PTHR16266:SF25 WD REPEAT DOMAIN 9 BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 3 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000002773.3|UniProtKB=G3QJX4 G3QJX4 PEX7 PTHR46027:SF1 PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR signal sequence receptor activity#GO:0005048 protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein transport#GO:0015031;peroxisomal transport#GO:0043574;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;peroxisome organization#GO:0007031;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;cytosol#GO:0005829;microbody#GO:0042579;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000005521.3|UniProtKB=G3QRY7 G3QRY7 ASB18 PTHR24126:SF68 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT AND SOCS BOX CONTAINING 18 GORGO|Ensembl=ENSGGOG00000000411.3|UniProtKB=G3S6W8 G3S6W8 ZFYVE16 PTHR46319:SF1 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 16 protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;protein localization to lysosome#GO:0061462;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;establishment of protein localization to vacuole#GO:0072666;protein localization to vacuole#GO:0072665;lysosomal transport#GO:0007041;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 TGF-beta signaling pathway#P00052>SARA#P01281 GORGO|Ensembl=ENSGGOG00000016007.3|UniProtKB=G3RIV1 G3RIV1 CTSF PTHR12411:SF444 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN F peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000009684.3|UniProtKB=G3R2K7 G3R2K7 TNS4 PTHR45734:SF6 TENSIN TENSIN-4 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000004602.3|UniProtKB=G3QPL3 G3QPL3 MOB3B PTHR22599:SF22 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3B protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000015833.3|UniProtKB=G3RID9 G3RID9 OTUD6B PTHR12419:SF21 OTU DOMAIN CONTAINING PROTEIN DEUBIQUITINASE OTUD6B deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000027399.2|UniProtKB=G3S1E6 G3S1E6 S100B PTHR11639:SF153 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-B cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of cell population proliferation#GO:0008284;positive regulation of signaling#GO:0023056;regulation of cell population proliferation#GO:0042127;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000007004.3|UniProtKB=A0A2I2ZH49 A0A2I2ZH49 NOSIP PTHR13063:SF10 ENOS INTERACTING PROTEIN NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000014960.3|UniProtKB=G3RG59 G3RG59 ZBTB44 PTHR24383:SF20 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000040635.1|UniProtKB=G3QG72 G3QG72 HOXD12 PTHR46440:SF1 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-D12 DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000014942.3|UniProtKB=G3SGM0 G3SGM0 CLCN7 PTHR11689:SF169 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 7 monoatomic anion channel activity#GO:0005253;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;active transmembrane transporter activity#GO:0022804;chloride channel activity#GO:0005254;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 membrane#GO:0016020;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;monoatomic ion channel complex#GO:0034702;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000042967.1|UniProtKB=A0A2I2Y3S5 A0A2I2Y3S5 LOC101142132 PTHR23428:SF232 HISTONE H2B HISTONE H2B TYPE 1-M defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;defense response#GO:0006952;response to external stimulus#GO:0009605;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000003771.3|UniProtKB=G3QMG1 G3QMG1 LHFPL2 PTHR12489:SF19 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 2 PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039093.1|UniProtKB=A0A2I2Z527 A0A2I2Z527 RBM24 PTHR48024:SF10 GEO13361P1-RELATED RNA-BINDING PROTEIN 24 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biosynthetic process#GO:0009891;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;positive regulation of cell differentiation#GO:0045597;negative regulation of RNA metabolic process#GO:0051253 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000008647.3|UniProtKB=G3QZX8 G3QZX8 LZTS3 PTHR19354:SF6 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 3-RELATED regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of synapse structure or activity#GO:0050803;regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological quality#GO:0065008;regulation of cell projection organization#GO:0031344;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse organization#GO:0050807 plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic spine#GO:0043197;neuron projection#GO:0043005;postsynapse#GO:0098794;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 GORGO|Ensembl=ENSGGOG00000043275.1|UniProtKB=A0A2I2Z0I0 A0A2I2Z0I0 RPS6KA4 PTHR24351:SF41 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-4 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;TORC1 signaling#GO:0038202;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;signaling#GO:0023052;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of nucleobase-containing compound metabolic process#GO:0019219;TOR signaling#GO:0031929;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;p38 MAPK pathway#P05918>MSK2#P06039;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 GORGO|Ensembl=ENSGGOG00000023731.2|UniProtKB=Q645Y8 Q645Y8 TAS2R4 PTHR11394:SF55 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 4 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027481.2|UniProtKB=G3S8N7 G3S8N7 FAM107B PTHR16768:SF1 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A PROTEIN FAM107B GORGO|Ensembl=ENSGGOG00000011247.3|UniProtKB=A0A2I2ZHB5 A0A2I2ZHB5 CARKD PTHR12592:SF0 ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 metabolic process#GO:0008152;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000005852.3|UniProtKB=A0A2I2ZW54 A0A2I2ZW54 DPF1 PTHR45888:SF14 HL01030P-RELATED ZINC FINGER PROTEIN NEURO-D4 transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription coregulator activity#GO:0003712;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 GORGO|Ensembl=ENSGGOG00000012250.3|UniProtKB=G3RX02 G3RX02 PPIP5K2 PTHR12750:SF10 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotide kinase#PC00172;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000001878.3|UniProtKB=A0A2I2Y7H3 A0A2I2Y7H3 TEX10 PTHR16056:SF39 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN TESTIS-EXPRESSED PROTEIN 10 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000011171.3|UniProtKB=G3R6E1 G3R6E1 BDH1 PTHR43313:SF25 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C D-BETA-HYDROXYBUTYRATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000044215.1|UniProtKB=G3R091 G3R091 FIS1 PTHR13247:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11 MITOCHONDRIAL FISSION 1 PROTEIN lipid binding#GO:0008289;binding#GO:0005488 peroxisome organization#GO:0007031;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266 organelle outer membrane#GO:0031968;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;membrane#GO:0016020;microbody#GO:0042579;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;peroxisome#GO:0005777;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867 GORGO|Ensembl=ENSGGOG00000003029.3|UniProtKB=A0A2I2YJK5 A0A2I2YJK5 MAP7D3 PTHR15073:SF5 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 3 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000006475.3|UniProtKB=G3QUD3 G3QUD3 PLSCR4 PTHR23248:SF28 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 4 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;intramembrane lipid carrier activity#GO:0140303 phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000038505.1|UniProtKB=G3QMP7 G3QMP7 KRT4 PTHR45616:SF3 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 4 structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;skin development#GO:0043588;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;epidermis development#GO:0008544;developmental process#GO:0032502;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 GORGO|Ensembl=ENSGGOG00000022006.2|UniProtKB=G3RYD8 G3RYD8 PRR32 PTHR37343:SF1 PROLINE-RICH PROTEIN 32 PROLINE-RICH PROTEIN 32 GORGO|Ensembl=ENSGGOG00000010146.3|UniProtKB=G3R3R5 G3R3R5 ZDHHC22 PTHR22883:SF213 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC22 catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 developmental maturation#GO:0021700;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;vesicle organization#GO:0016050;protein targeting to membrane#GO:0006612;developmental process#GO:0032502;protein targeting#GO:0006605;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000013684.3|UniProtKB=G3RCW3 G3RCW3 NTN4 PTHR10574:SF282 NETRIN/LAMININ-RELATED NETRIN-4 cell motility#GO:0048870;external encapsulating structure organization#GO:0045229;system development#GO:0048731;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;cell-substrate adhesion#GO:0031589;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;extracellular matrix assembly#GO:0085029;cell migration#GO:0016477;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular component assembly#GO:0022607;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182 basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357;Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000012324.3|UniProtKB=G3S1S9 G3S1S9 TLR8 PTHR47410:SF1 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 8 signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of gene expression#GO:0010628;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to virus#GO:0009615;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;toll-like receptor signaling pathway#GO:0002224;defense response to virus#GO:0051607;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 GORGO|Ensembl=ENSGGOG00000008962.3|UniProtKB=G3R0R6 G3R0R6 LOC101123709 PTHR24412:SF23 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 7 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;regulation of small GTPase mediated signal transduction#GO:0051056;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011056.3|UniProtKB=G3R635 G3R635 ZNF331 PTHR24381:SF458 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 697 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000002364.3|UniProtKB=G3QIV8 G3QIV8 AGFG1 PTHR46134:SF1 DRONGO, ISOFORM F ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 1 developmental process#GO:0032502;spermatogenesis#GO:0007283;nucleus organization#GO:0006997;cellular developmental process#GO:0048869;male gamete generation#GO:0048232;sexual reproduction#GO:0019953;spermatid development#GO:0007286;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;acrosome assembly#GO:0001675;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;spermatid differentiation#GO:0048515;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;gamete generation#GO:0007276 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000000719.3|UniProtKB=G3QEL3 G3QEL3 NUP160 PTHR21286:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP160 NUCLEAR PORE COMPLEX PROTEIN NUP160 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;response to nitrogen compound#GO:1901698;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;RNA localization#GO:0006403;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;telomere localization#GO:0034397;cellular response to stimulus#GO:0051716;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;macromolecule biosynthetic process#GO:0009059;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;protein import into nucleus#GO:0006606;protein transport#GO:0015031;ribosome biogenesis#GO:0042254;telomere tethering at nuclear periphery#GO:0034398;cellular response to stress#GO:0033554;establishment of organelle localization#GO:0051656;response to stimulus#GO:0050896;ribonucleoprotein complex biogenesis#GO:0022613;response to abiotic stimulus#GO:0009628;cellular component organization#GO:0016043;ribosomal large subunit export from nucleus#GO:0000055;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;gene expression#GO:0010467;response to chemical#GO:0042221;chromosome localization#GO:0050000;response to temperature stimulus#GO:0009266;protein export from nucleus#GO:0006611;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;response to heat#GO:0009408;organelle organization#GO:0006996;cellular response to heat#GO:0034605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003467.3|UniProtKB=G3QLP7 G3QLP7 KRT1 PTHR45616:SF33 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 1 structural molecule activity#GO:0005198 supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;developmental process#GO:0032502;epidermis development#GO:0008544;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;cellular process#GO:0009987;organelle organization#GO:0006996 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000010704.3|UniProtKB=G3R569 G3R569 TGDS PTHR43000:SF54 DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED UDP-D-GLUCOSE 4,6-DEHYDRATASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 dehydratase#PC00091 O-antigen biosynthesis#P02757>dTDP-glucose 4,6-dehydratase#P03045 GORGO|Ensembl=ENSGGOG00000012451.3|UniProtKB=A0A2I2YRA8 A0A2I2YRA8 PTHR48002:SF83 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043161.1|UniProtKB=A0A2I2ZKF3 A0A2I2ZKF3 PTHR24412:SF437 KELCH PROTEIN BTB DOMAIN-CONTAINING PROTEIN enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein metabolic process#GO:0019538;localization#GO:0051179;membrane organization#GO:0061024;transport#GO:0006810;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;ubiquitin-dependent protein catabolic process#GO:0006511;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;proteasomal protein catabolic process#GO:0010498;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;Golgi vesicle transport#GO:0048193;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;ubiquitin ligase complex#GO:0000151;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012381.3|UniProtKB=A0A2I2YFS6 A0A2I2YFS6 CCDC88A PTHR18947:SF30 HOOK PROTEINS GIRDIN tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cytoplasmic microtubule organization#GO:0031122;cellular component organization#GO:0016043;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000004977.3|UniProtKB=G3SKP7 G3SKP7 LOC101144812 PTHR11616:SF96 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;amino acid transport#GO:0006865;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 GORGO|Ensembl=ENSGGOG00000037497.1|UniProtKB=A0A2I2YUC9 A0A2I2YUC9 LOC101123748 PTHR11515:SF25 GLYCOPROTEIN HORMONE BETA CHAIN CHORIOGONADOTROPIN SUBUNIT BETA 3-RELATED receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;developmental process involved in reproduction#GO:0003006;signaling#GO:0023052;reproductive process#GO:0022414;reproductive structure development#GO:0048608;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;female gonad development#GO:0008585;system development#GO:0048731;reproductive system development#GO:0061458;cell communication#GO:0007154;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;sex differentiation#GO:0007548;biological regulation#GO:0065007;gonad development#GO:0008406;multicellular organismal process#GO:0032501;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000005176.3|UniProtKB=G3QR38 G3QR38 PHLPP1 PTHR45752:SF58 LEUCINE-RICH REPEAT-CONTAINING PH DOMAIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN PHOSPHATASE 1 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000024258.2|UniProtKB=G3SCS7 G3SCS7 MFAP3L PTHR14340:SF2 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 MICROFIBRILLAR-ASSOCIATED PROTEIN 3-LIKE GORGO|Ensembl=ENSGGOG00000001525.3|UniProtKB=G3QGP4 G3QGP4 CENPH PTHR48122:SF1 CENTROMERE PROTEIN H CENTROMERE PROTEIN H binding#GO:0005488 chromosome segregation#GO:0007059;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000023387.2|UniProtKB=A0A2I2YMR2 A0A2I2YMR2 NBR1 PTHR20930:SF2 OVARIAN CARCINOMA ANTIGEN CA125-RELATED NEXT TO BRCA1 GENE 1 PROTEIN protein targeting#GO:0006605;protein localization to organelle#GO:0033365;establishment of protein localization to vacuole#GO:0072666;catabolic process#GO:0009056;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;protein localization to vacuole#GO:0072665;macroautophagy#GO:0016236;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;autophagosome#GO:0005776;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000040932.1|UniProtKB=A0A2I2ZQI4 A0A2I2ZQI4 SERTM1 PTHR35660:SF1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000027870.2|UniProtKB=A0A2K5TIY4 A0A2K5TIY4 CAV1 PTHR10844:SF18 CAVEOLIN CAVEOLIN-1 protein binding#GO:0005515;protein kinase binding#GO:0019901;transmembrane transporter binding#GO:0044325;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488 plasma membrane organization#GO:0007009;regulation of cell population proliferation#GO:0042127;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of cytosolic calcium ion concentration#GO:0051480;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of cell population proliferation#GO:0008285;monoatomic ion homeostasis#GO:0050801;cellular component biogenesis#GO:0044085 Golgi apparatus#GO:0005794;membrane microdomain#GO:0098857;cell junction#GO:0030054;sarcolemma#GO:0042383;membrane#GO:0016020;caveola#GO:0005901;cell periphery#GO:0071944;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;plasma membrane raft#GO:0044853;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;membrane raft#GO:0045121;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>Caveolin-1#P06763;Integrin signalling pathway#P00034>Caveolin#P00918 GORGO|Ensembl=ENSGGOG00000038726.1|UniProtKB=A0A2I2YZ94 A0A2I2YZ94 PTHR23266:SF322 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-2 binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000010828.3|UniProtKB=G3R5I1 G3R5I1 SLC23A3 PTHR11119:SF57 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 3 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011576.3|UniProtKB=G3SHE5 G3SHE5 TAF8 PTHR46469:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 General transcription by RNA polymerase I#P00022>TAF-IB#P00650;General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>TAF-IC#P00649;General transcription regulation#P00023>TBP-associated factors#P00658;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 GORGO|Ensembl=ENSGGOG00000042981.1|UniProtKB=A0A2I2ZAL1 A0A2I2ZAL1 LOC101150759 PTHR48018:SF85 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M10 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000023952.2|UniProtKB=G3S9G4 G3S9G4 LOC101146459 PTHR48018:SF132 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003078.3|UniProtKB=G3RVS9 G3RVS9 LIMK1 PTHR46485:SF7 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;positive regulation of organelle organization#GO:0010638;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament-based process#GO:0032970;positive regulation of actin filament bundle assembly#GO:0032233;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cell projection#GO:0042995;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;nucleus#GO:0005634 Cytoskeletal regulation by Rho GTPase#P00016>LIMK#P00524 GORGO|Ensembl=ENSGGOG00000001342.3|UniProtKB=G3QG75 G3QG75 GALR1 PTHR24230:SF31 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000011087.3|UniProtKB=G3R668 G3R668 SLC25A35 PTHR45928:SF2 RE38146P SOLUTE CARRIER FAMILY 25 MEMBER 35 GORGO|Ensembl=ENSGGOG00000024588.2|UniProtKB=Q6WUX8 Q6WUX8 CYCS PTHR11961:SF29 CYTOCHROME C CYTOCHROME C metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthesis#P02721>Cyt C#P02798;Apoptosis signaling pathway#P00006>Cytochrome C#P00322 GORGO|Ensembl=ENSGGOG00000009709.3|UniProtKB=G3R2M6 G3R2M6 NPTX1 PTHR19277:SF24 PENTRAXIN NEURONAL PENTRAXIN-1 cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;axon development#GO:0061564;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000043021.1|UniProtKB=A0A2I2YH47 A0A2I2YH47 ZNF823 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 670 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011375.3|UniProtKB=A0A2I2ZHI5 A0A2I2ZHI5 ZDHHC12 PTHR22883:SF514 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC12 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011074.4|UniProtKB=G3R658 G3R658 KIAA1328 PTHR28375:SF1 PROTEIN HINDERIN PROTEIN HINDERIN GORGO|Ensembl=ENSGGOG00000025370.1|UniProtKB=G3S3I9 G3S3I9 ATP6 PTHR11410:SF0 ATP SYNTHASE SUBUNIT A ATP SYNTHASE F(0) COMPLEX SUBUNIT A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;organophosphate biosynthetic process#GO:0090407;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 ATP synthesis#P02721>ATP synthetase F0#P02797 GORGO|Ensembl=ENSGGOG00000003548.3|UniProtKB=A0A2I2Z406 A0A2I2Z406 FNBP1 PTHR15735:SF13 FCH AND DOUBLE SH3 DOMAINS PROTEIN FORMIN-BINDING PROTEIN 1 regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of actin filament-based process#GO:0032970;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000034854.2|UniProtKB=A0A2I2YE25 A0A2I2YE25 CRYZ PTHR44154:SF1 QUINONE OXIDOREDUCTASE ZETA-CRYSTALLIN purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;ion binding#GO:0043167;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;anion binding#GO:0043168;RNA binding#GO:0003723 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Huntington disease#P00029>PIG3#G01535 GORGO|Ensembl=ENSGGOG00000015323.3|UniProtKB=G3RH43 G3RH43 PHLDB1 PTHR12156:SF23 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 1 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;basal part of cell#GO:0045178 GORGO|Ensembl=ENSGGOG00000005000.3|UniProtKB=G3QQM9 G3QQM9 NGDN PTHR13237:SF9 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED NEUROGUIDIN cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 GORGO|Gene=OR3A2|UniProtKB=Q9TU88 Q9TU88 OR3A2 PTHR26453:SF626 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001737.3|UniProtKB=A0A2I2Y6I5 A0A2I2Y6I5 KCNQ3 PTHR47735:SF11 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 3 voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024293.2|UniProtKB=G3SH53 G3SH53 LOC134757555 PTHR13218:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TATA-BOX-BINDING PROTEIN-ASSOCIATED FACTOR 11-LIKE PROTEIN 10-RELATED RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Gene=TLR4|UniProtKB=Q8SPE8 Q8SPE8 TLR4 PTHR24365:SF521 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 4 lipid binding#GO:0008289;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;lipopolysaccharide binding#GO:0001530;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;inflammatory response#GO:0006954;response to bacterium#GO:0009617;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;positive regulation of innate immune response#GO:0045089;detection of stimulus#GO:0051606;activation of innate immune response#GO:0002218;response to other organism#GO:0051707;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;toll-like receptor 4 signaling pathway#GO:0034142;positive regulation of response to stimulus#GO:0048584;defense response to bacterium#GO:0042742;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;detection of chemical stimulus#GO:0009593;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;toll-like receptor signaling pathway#GO:0002224;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;signaling#GO:0023052;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;regulation of response to external stimulus#GO:0032101;response to lipid#GO:0033993;response to chemical#GO:0042221 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR#P01346;Toll receptor signaling pathway#P00054>TLR4#P01339 GORGO|Ensembl=ENSGGOG00000003433.3|UniProtKB=G3QLL6 G3QLL6 HROB PTHR14523:SF1 UNCHARACTERIZED PROTEIN C17ORF53 HOMOLOG HOMOLOGOUS RECOMBINATION OB-FOLD PROTEIN GORGO|Ensembl=ENSGGOG00000025886.2|UniProtKB=G3S7L7 G3S7L7 TMEM92 PTHR31359:SF31 TRANSMEMBRANE PROTEIN 92 TRANSMEMBRANE PROTEIN 92 GORGO|Ensembl=ENSGGOG00000006751.3|UniProtKB=G3QV50 G3QV50 NFX1 PTHR12360:SF16 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 TRANSCRIPTIONAL REPRESSOR NF-X1 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000001371.3|UniProtKB=G3QGA2 G3QGA2 CISD2 PTHR13680:SF33 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 2 transaminase activity#GO:0008483;small molecule binding#GO:0036094;binding#GO:0005488;transferase activity#GO:0016740;catalytic activity#GO:0003824;iron-sulfur cluster binding#GO:0051536 monoatomic ion homeostasis#GO:0050801;autophagy#GO:0006914;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;catabolic process#GO:0009056;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;process utilizing autophagic mechanism#GO:0061919;inorganic ion homeostasis#GO:0098771 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000016757.3|UniProtKB=G3RKT7 G3RKT7 LAMB4 PTHR10574:SF279 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-4 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;extracellular matrix assembly#GO:0085029;cell migration#GO:0016477;multicellular organismal process#GO:0032501;external encapsulating structure organization#GO:0045229;system development#GO:0048731;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;cell motility#GO:0048870;neuron differentiation#GO:0030182;substrate adhesion-dependent cell spreading#GO:0034446;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular component assembly#GO:0022607;cell adhesion#GO:0007155;generation of neurons#GO:0048699;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902 basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000037617.1|UniProtKB=A0A2I2YDP7 A0A2I2YDP7 RTL5 PTHR15503:SF51 LDOC1 RELATED RETROTRANSPOSON GAG-LIKE PROTEIN 5 viral or transposable element protein#PC00237 GORGO|Gene=KLF14|UniProtKB=Q14V87 Q14V87 KLF14 PTHR23235:SF59 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 14 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005475.3|UniProtKB=A0A2I2YCK4 A0A2I2YCK4 PTHR22776:SF84 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;myelination#GO:0042552;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;signaling#GO:0023052;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731 apical part of cell#GO:0045177;cell periphery#GO:0071944;membrane#GO:0016020;apical plasma membrane#GO:0016324;myelin sheath#GO:0043209;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040090.1|UniProtKB=A0A2I2YN61 A0A2I2YN61 PTHR46909:SF2 39S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL RIBOSOMAL PROTEIN ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006171.3|UniProtKB=G3QTK7 G3QTK7 NRSN2 PTHR14796:SF5 NEURENSIN 1-RELATED NEURENSIN-2 system development#GO:0048731;nervous system development#GO:0007399;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cell body#GO:0044297;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000024247.2|UniProtKB=A0A2I2ZJM0 A0A2I2ZJM0 ECHDC1 PTHR11941:SF27 ENOYL-COA HYDRATASE-RELATED ETHYLMALONYL-COA DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 GORGO|Ensembl=ENSGGOG00000026421.2|UniProtKB=G3SHT4 G3SHT4 PTHR15481:SF12 RIBONUCLEIC ACID BINDING PROTEIN S1 RNA-BINDING PROTEIN WITH SERINE-RICH DOMAIN 1 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004206.3|UniProtKB=G3QNK8 G3QNK8 MAGEE2 PTHR11736:SF7 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN E2 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010638.3|UniProtKB=G3R514 G3R514 BPIFB6 PTHR46019:SF2 BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED BPI FOLD-CONTAINING FAMILY B MEMBER 6 GORGO|Ensembl=ENSGGOG00000012757.3|UniProtKB=G3RAG8 G3RAG8 BCL2L14 PTHR14965:SF1 SI:CH73-248E21.1 APOPTOSIS FACILITATOR BCL-2-LIKE PROTEIN 14 regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of apoptotic process#GO:0043065;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of programmed cell death#GO:0043068 GORGO|Ensembl=ENSGGOG00000003056.3|UniProtKB=G3QKN0 G3QKN0 POLA2 PTHR23061:SF12 DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT DNA POLYMERASE ALPHA SUBUNIT B macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;nuclear DNA-directed RNA polymerase complex#GO:0055029;replisome#GO:0030894;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 GORGO|Ensembl=ENSGGOG00000023840.2|UniProtKB=G3S2R7 G3S2R7 PTHR11544:SF68 COLD SHOCK DOMAIN CONTAINING PROTEINS Y BOX BINDING PROTEIN 1 LIKE 1 nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000039124.1|UniProtKB=A0A2I2YSR8 A0A2I2YSR8 NUCKS1 PTHR15361:SF1 RAD51/NUKS-INTERACTING PROTEIN NUCLEAR UBIQUITOUS CASEIN AND CYCLIN-DEPENDENT KINASE SUBSTRATE 1 binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003676.3|UniProtKB=G3QM80 G3QM80 PTHR12487:SF5 TEASHIRT-RELATED TEASHIRT HOMOLOG 3 DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of system process#GO:0044057;system process#GO:0003008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nervous system process#GO:0050877;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000002825.3|UniProtKB=G3QK20 G3QK20 HSD17B3 PTHR43899:SF7 RH59310P 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;steroid biosynthetic process#GO:0006694;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 GORGO|Ensembl=ENSGGOG00000037591.1|UniProtKB=A0A2I2YW62 A0A2I2YW62 PTHR23331:SF3 CXYORF1 WAS PROTEIN FAMILY HOMOLOG 4-RELATED cellular component organization#GO:0016043;export from cell#GO:0140352;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;localization within membrane#GO:0051668;actin filament-based process#GO:0030029;secretion by cell#GO:0032940;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;actin filament organization#GO:0007015;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;exocytosis#GO:0006887;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;recycling endosome#GO:0055037;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000016302.3|UniProtKB=A0A2I2YVR8 A0A2I2YVR8 ZFR PTHR45762:SF21 ZINC FINGER RNA-BINDING PROTEIN ZINC FINGER RNA-BINDING PROTEIN single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000022116.2|UniProtKB=A0A2I2YLW8 A0A2I2YLW8 GULP1 PTHR11232:SF78 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PTB DOMAIN-CONTAINING ENGULFMENT ADAPTER PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 cellular component organization#GO:0016043;cellular process#GO:0009987;endocytosis#GO:0006897;membrane organization#GO:0061024;phagocytosis#GO:0006909;membrane invagination#GO:0010324;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;phagocytosis, engulfment#GO:0006911;establishment of localization#GO:0051234;import into cell#GO:0098657 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005605.3|UniProtKB=A0A2I2ZNI9 A0A2I2ZNI9 LY9 PTHR12080:SF114 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE T-LYMPHOCYTE SURFACE ANTIGEN LY-9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;cell activation#GO:0001775;immune system process#GO:0002376;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;T cell activation#GO:0042110;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000001255.3|UniProtKB=A0A2I2YTX4 A0A2I2YTX4 GOSR2 PTHR21230:SF99 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 2 protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;localization#GO:0051179 SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle#GO:0030133;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507 membrane traffic protein#PC00150;SNARE protein#PC00034 GORGO|Ensembl=ENSGGOG00000001158.3|UniProtKB=A0A2I2ZYZ1 A0A2I2ZYZ1 SLAIN1 PTHR22406:SF2 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM SLAIN MOTIF-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;regulation of organelle organization#GO:0033043;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;cytoplasmic microtubule organization#GO:0031122;positive regulation of cellular component organization#GO:0051130;regulation of microtubule polymerization#GO:0031113;positive regulation of organelle organization#GO:0010638;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;regulation of supramolecular fiber organization#GO:1902903;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;positive regulation of cellular process#GO:0048522;microtubule polymerization or depolymerization#GO:0031109;biological regulation#GO:0065007;positive regulation of protein polymerization#GO:0032273;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule polymerization#GO:0046785 microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;microtubule plus-end#GO:0035371;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 GORGO|Ensembl=ENSGGOG00000043451.1|UniProtKB=A0A2I2ZAH6 A0A2I2ZAH6 NHLH2 PTHR13864:SF19 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED HELIX-LOOP-HELIX PROTEIN 2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000036550.1|UniProtKB=G3SC43 G3SC43 LOC101143221 PTHR23262:SF237 KERATIN ASSOCIATED PROTEIN SUBFAMILY NOT NAMED structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000025705.2|UniProtKB=G3RQI9 G3RQI9 PTHR17616:SF9 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER TRANSCRIPTIONAL COACTIVATOR YAP1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;hippo signaling#GO:0035329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000006568.3|UniProtKB=G3QUM1 G3QUM1 RNF6 PTHR45931:SF2 SI:CH211-59O9.10 E3 UBIQUITIN-PROTEIN LIGASE RNF6 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;protein ubiquitination#GO:0016567;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013340.3|UniProtKB=G3RUF8 G3RUF8 ALDH1B1 PTHR11699:SF207 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER B1, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 metabolic process#GO:0008152;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;catabolic process#GO:0009056;aldehyde catabolic process#GO:0046185 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000002829.3|UniProtKB=G3QK24 G3QK24 GDAP1 PTHR44188:SF3 GDAP1, ISOFORM A GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 1 organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266;organelle fusion#GO:0048284;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000026033.2|UniProtKB=G3RNN8 G3RNN8 RGS17 PTHR10845:SF196 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 17 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 GORGO|Ensembl=ENSGGOG00000001483.3|UniProtKB=G3QGK5 G3QGK5 IFT43 PTHR33724:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782 intraciliary transport particle#GO:0030990;cilium#GO:0005929;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000027655.2|UniProtKB=G3RSG3 G3RSG3 PTHR11681:SF9 NEUROPHYSIN VASOPRESSIN-NEUROPHYSIN 2-COPEPTIN neuropeptide hormone activity#GO:0005184;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of blood pressure#GO:0045777;signaling#GO:0023052;circulatory system process#GO:0003013;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;system process#GO:0003008 secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;extracellular region#GO:0005576;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503 neuropeptide#PC00162;peptide hormone#PC00179 Vasopressin synthesis#P04395>Pro-Vasopressin#P04598;Vasopressin synthesis#P04395>Pro2-Vasopressin#P04595;Vasopressin synthesis#P04395>Neurophysin#P04594;Vasopressin synthesis#P04395>Signal Peptide#P04597;Vasopressin synthesis#P04395>Glycopeptide#P04593;Opioid prodynorphin pathway#P05916>prepropressophysin#G06050;Opioid prodynorphin pathway#P05916>vasopressin#P06000;Vasopressin synthesis#P04395>Vasopressin#P04590;Opioid prodynorphin pathway#P05916>provasopressin#P05999;Vasopressin synthesis#P04395>Pro-Neurophysin#P04591;Opioid prodynorphin pathway#P05916>prepropressophysin#G06048 GORGO|Ensembl=ENSGGOG00000001780.3|UniProtKB=G3QHC9 G3QHC9 GRIN1 PTHR18966:SF377 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1 transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;dicarboxylic acid transmembrane transporter activity#GO:0005310 cell surface receptor signaling pathway#GO:0007166;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896 signaling receptor complex#GO:0043235;cell junction#GO:0030054;transporter complex#GO:1990351;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NR1#P01010 GORGO|Ensembl=ENSGGOG00000005847.3|UniProtKB=G3QST0 G3QST0 KMT5C PTHR12977:SF11 SUPPRESSOR OF VARIEGATION 4-20-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE KMT5C protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000000503.3|UniProtKB=A0A2I2YEE0 A0A2I2YEE0 PRMT1 PTHR11006:SF54 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 1 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;histone modifying activity#GO:0140993 chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016412.3|UniProtKB=G3RJW1 G3RJW1 DCTD PTHR11086:SF23 DEOXYCYTIDYLATE DEAMINASE-RELATED DEOXYCYTIDYLATE DEAMINASE catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside monophosphate biosynthetic process#GO:0009124;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000009609.3|UniProtKB=G3R2D8 G3R2D8 WEE2 PTHR11042:SF75 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;regulation of cellular component organization#GO:0051128;regulation of reproductive process#GO:2000241;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000027527.2|UniProtKB=G3SA10 G3SA10 CAP1 PTHR10652:SF1 ADENYLYL CYCLASE-ASSOCIATED PROTEIN ADENYLYL CYCLASE-ASSOCIATED PROTEIN 1 enzyme binding#GO:0019899;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cell morphogenesis#GO:0000902;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000003242.3|UniProtKB=G3QL48 G3QL48 BPIFB1 PTHR47395:SF1 BPI FOLD-CONTAINING FAMILY B MEMBER 1 BPI FOLD-CONTAINING FAMILY B MEMBER 1 regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;immune response#GO:0006955;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;response to other organism#GO:0051707;negative regulation of response to stimulus#GO:0048585;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 GORGO|Ensembl=ENSGGOG00000007060.3|UniProtKB=G3QVX9 G3QVX9 ATP13A4 PTHR45630:SF1 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE 13A4-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;polyamine transmembrane transporter activity#GO:0015203 homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;localization#GO:0051179;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic ion homeostasis#GO:0050801;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome membrane#GO:0010008;endosome#GO:0005768;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;late endosome membrane#GO:0031902 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000002961.3|UniProtKB=G3QKD8 G3QKD8 PTHR24028:SF46 CADHERIN-87A PROTOCADHERIN-8 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000012526.3|UniProtKB=G3R9X6 G3R9X6 ENGASE PTHR13246:SF1 ENDO BETA N-ACETYLGLUCOSAMINIDASE CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 deaminase#PC00088;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000004546.3|UniProtKB=A0A2I2ZK06 A0A2I2ZK06 FRMD3 PTHR23280:SF8 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN 3 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000007038.3|UniProtKB=G3QVU8 G3QVU8 HHATL PTHR13285:SF19 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE HHAT-LIKE PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of protein modification process#GO:0031399;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000002930.3|UniProtKB=G3QKB5 G3QKB5 RPS6KA1 PTHR24351:SF43 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;TOR signaling#GO:0031929;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;TORC1 signaling#GO:0038202;regulation of DNA-templated transcription#GO:0006355;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 protein modifying enzyme#PC00260 CCKR signaling map#P06959>RSK1/2#P07153;PDGF signaling pathway#P00047>p90RSK#P01142;Ras Pathway#P04393>p90RSK#P04541;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Interleukin signaling pathway#P00036>p90RSK#P00964 GORGO|Ensembl=ENSGGOG00000025695.2|UniProtKB=A0A2I2YUU0 A0A2I2YUU0 PTHR17614:SF13 ZINC FINGER-CONTAINING ZINC FINGER PROTEIN 804A cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000025445.2|UniProtKB=G3S5W0 G3S5W0 LMO3 PTHR45787:SF7 LD11652P LIM DOMAIN ONLY PROTEIN 3 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000025730.2|UniProtKB=G3SA62 G3SA62 PTHR10394:SF12 40S RIBOSOMAL PROTEIN S8 SMALL RIBOSOMAL SUBUNIT PROTEIN ES8 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000028040.2|UniProtKB=G3SHK6 G3SHK6 PTHR11528:SF96 HEAT SHOCK PROTEIN 90 FAMILY MEMBER ENDOPLASMIN ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;ATP-dependent activity#GO:0140657 protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 chaperone#PC00072;Hsp90 family chaperone#PC00028 GORGO|Ensembl=ENSGGOG00000007054.3|UniProtKB=G3QVW3 G3QVW3 COLEC10 PTHR22799:SF8 TETRANECTIN-RELATED COLLECTIN SUBFAMILY MEMBER 10 multicellular organismal process#GO:0032501;ossification#GO:0001503 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000014173.3|UniProtKB=A0A2I2ZYW2 A0A2I2ZYW2 MYADM PTHR17068:SF17 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER negative regulation of cellular process#GO:0048523;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161 GORGO|Ensembl=ENSGGOG00000027673.2|UniProtKB=G3RPD7 G3RPD7 LOC101146784 PTHR11593:SF51 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016893.3|UniProtKB=G3RL56 G3RL56 UBE2O PTHR46116:SF51 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000015932.3|UniProtKB=G3RIP0 G3RIP0 NISCH PTHR15454:SF35 NISCHARIN RELATED NISCHARIN intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Rac protein signal transduction#GO:0016601;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014126.3|UniProtKB=G3RE13 G3RE13 PTHR13518:SF1 PUTATIVE TREBLE-CLEF ZINC-FINGER C2ORF42 FAMILY MEMBER RGD1306746 PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000001165.3|UniProtKB=G3QFR9 G3QFR9 FDFT1 PTHR11626:SF8 FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE SQUALENE SYNTHASE prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;phospholipid metabolic process#GO:0006644;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transferase#PC00220 Cholesterol biosynthesis#P00014>Farnesyl-diphosphate farnesyltransferase#P00499 GORGO|Ensembl=ENSGGOG00000014097.3|UniProtKB=G3RDY9 G3RDY9 ICOS PTHR20904:SF0 INDUCIBLE T-CELL COSTIMULATOR ICOS INDUCIBLE T-CELL COSTIMULATOR positive regulation of cell adhesion#GO:0045785;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;system development#GO:0048731;anatomical structure development#GO:0048856;positive regulation of lymphocyte activation#GO:0051251;positive regulation of cellular process#GO:0048522;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;immune system development#GO:0002520;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;regulation of multicellular organismal process#GO:0051239;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;positive regulation of leukocyte activation#GO:0002696;multicellular organism development#GO:0007275 GORGO|Ensembl=ENSGGOG00000010611.3|UniProtKB=G3SHT5 G3SHT5 POU2AF1 PTHR15363:SF3 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000017173.3|UniProtKB=G3RLU9 G3RLU9 PLPP7 PTHR14969:SF17 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE INACTIVE PHOSPHOLIPID PHOSPHATASE 7 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;dephosphorylation#GO:0016311;lipid modification#GO:0030258 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000007367.3|UniProtKB=A0A2I2Y5E0 A0A2I2Y5E0 GSK3B PTHR24057:SF8 GLYCOGEN SYNTHASE KINASE-3 ALPHA GLYCOGEN SYNTHASE KINASE-3 BETA protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;beta-catenin binding#GO:0008013;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;positive regulation of neuron apoptotic process#GO:0043525;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;positive regulation of catabolic process#GO:0009896;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of catabolic process#GO:0009894;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of microtubule-based process#GO:0032886;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;insulin receptor signaling pathway#GO:0008286;negative regulation of cell communication#GO:0010648;cellular response to nitrogen compound#GO:1901699;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signal transduction#GO:0009966;developmental process#GO:0032502;cellular developmental process#GO:0048869;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cytoskeleton organization#GO:0051493;negative regulation of TOR signaling#GO:0032007;cellular response to peptide hormone stimulus#GO:0071375;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cell communication#GO:0007154;regulation of protein catabolic process#GO:0042176;response to nitrogen compound#GO:1901698;positive regulation of protein catabolic process#GO:0045732;response to hormone#GO:0009725;regulation of protein metabolic process#GO:0051246;positive regulation of autophagy#GO:0010508;regulation of neuron apoptotic process#GO:0043523;regulation of TOR signaling#GO:0032006;response to chemical#GO:0042221;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;response to endogenous stimulus#GO:0009719;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of programmed cell death#GO:0043067;positive regulation of programmed cell death#GO:0043068;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;negative regulation of canonical Wnt signaling pathway#GO:0090090;positive regulation of protein metabolic process#GO:0051247;response to oxygen-containing compound#GO:1901700;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axon#GO:0030424;catalytic complex#GO:1902494;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;dendrite#GO:0030425;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;glutamatergic synapse#GO:0098978;protein-containing complex#GO:0032991;neuron projection#GO:0043005;nucleus#GO:0005634;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;cell junction#GO:0030054 non-receptor serine/threonine protein kinase#PC00167 Cadherin signaling pathway#P00012>GSK3beta#P00477;Hedgehog signaling pathway#P00025>GSK3#P00692;Interleukin signaling pathway#P00036>GSK3#P00976;Ras Pathway#P04393>GSK3#P04546;CCKR signaling map#P06959>GSK3beta#P07199;Gonadotropin-releasing hormone receptor pathway#P06664>GSK3#P06827;Angiogenesis#P00005>GSK3beta#P00211;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GSK#P00714;Wnt signaling pathway#P00057>Glycogen Synthase Kinase-3Beta#P01441;Alzheimer disease-presenilin pathway#P00004>GSK-3beta#P00175;PI3 kinase pathway#P00048>GSK3#P01181;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PDGF signaling pathway#P00047>GSK3#P01153 GORGO|Ensembl=ENSGGOG00000024446.2|UniProtKB=A0A2I2Z8G8 A0A2I2Z8G8 PTHR10497:SF12 60S RIBOSOMAL PROTEIN L27 60S RIBOSOMAL PROTEIN L27 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009298.3|UniProtKB=A0A2I2YTA9 A0A2I2YTA9 SORCS1 PTHR12106:SF8 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS1 transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000040155.1|UniProtKB=A0A2I2ZQ92 A0A2I2ZQ92 PTHR15141:SF74 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN A2 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000008290.3|UniProtKB=G3R9H0 G3R9H0 PCDHB12 PTHR24028:SF334 CADHERIN-87A PROTOCADHERIN BETA-12 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000001240.3|UniProtKB=G3QFY4 G3QFY4 RASIP1 PTHR16027:SF4 DILUTE DOMAIN-CONTAINING PROTEIN YPR089W RAS-INTERACTING PROTEIN 1 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 negative regulation of signal transduction#GO:0009968;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;regulation of small GTPase mediated signal transduction#GO:0051056;multicellular organism development#GO:0007275;regulation of Rho protein signal transduction#GO:0035023;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;angiogenesis#GO:0001525;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;negative regulation of signaling#GO:0023057;tube development#GO:0035295;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;system development#GO:0048731;anatomical structure development#GO:0048856 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 GORGO|Ensembl=ENSGGOG00000028098.2|UniProtKB=G3SEN9 G3SEN9 PTHR22747:SF31 NUCLEOPLASMIN NUCLEOPLASMIN CORE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;RNA binding#GO:0003723;chromatin binding#GO:0003682;histone binding#GO:0042393;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;ribosomal large subunit export from nucleus#GO:0000055;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;regulation of cell cycle#GO:0051726;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular localization#GO:0051641;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;regulation of cell cycle process#GO:0010564;positive regulation of macromolecule metabolic process#GO:0010604;ribosomal small subunit biogenesis#GO:0042274;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;regulation of microtubule-based process#GO:0032886;nuclear export#GO:0051168;regulation of RNA metabolic process#GO:0051252;nuclear transport#GO:0051169;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000015158.3|UniProtKB=G3RGN9 G3RGN9 LOC101140208 PTHR23320:SF135 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 6A regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004301.3|UniProtKB=G3S5P2 G3S5P2 SMIM23 PTHR37865:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 23 SMALL INTEGRAL MEMBRANE PROTEIN 23 GORGO|Ensembl=ENSGGOG00000015831.3|UniProtKB=G3RIE7 G3RIE7 ARHGAP44 PTHR14130:SF13 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 44 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of neuron projection development#GO:0010975;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse organization#GO:0050807;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of synapse structure or activity#GO:0050803;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 presynaptic active zone#GO:0048786;cell junction#GO:0030054;cell periphery#GO:0071944;presynapse#GO:0098793;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;dendrite#GO:0030425;dendritic spine#GO:0043197;postsynapse#GO:0098794;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000000541.3|UniProtKB=G3QE47 G3QE47 PTHR45805:SF3 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-ALPHA binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sterol binding#GO:0032934;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;lipid binding#GO:0008289;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;steroid binding#GO:0005496 regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of response to external stimulus#GO:0032102;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000001237.3|UniProtKB=A0A2I2YLS8 A0A2I2YLS8 MAMSTR PTHR23251:SF1 LYSINE-RICH CEACAM1 CO-ISOLATED PROTEIN LYRIC PROTEIN MEF2-ACTIVATING MOTIF AND SAP DOMAIN-CONTAINING TRANSCRIPTIONAL REGULATOR transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000000226.3|UniProtKB=G3S337 G3S337 LDAH PTHR13390:SF4 LIPASE LIPID DROPLET-ASSOCIATED HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;organelle organization#GO:0006996;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;lipid droplet organization#GO:0034389;cholesterol homeostasis#GO:0042632;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 lipase#PC00143;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000002138.3|UniProtKB=A0A2I2YA74 A0A2I2YA74 SPACA9 PTHR32455:SF1 SPERM ACROSOME-ASSOCIATED PROTEIN 9 SPERM ACROSOME-ASSOCIATED PROTEIN 9 sperm flagellum#GO:0036126;endomembrane system#GO:0012505;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;ciliary base#GO:0097546;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;acrosomal vesicle#GO:0001669;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;intracellular vesicle#GO:0097708;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000007995.3|UniProtKB=A0A2I2YEI8 A0A2I2YEI8 LLCFC1 PTHR37348:SF1 LLLL AND CFNLAS MOTIF-CONTAINING PROTEIN 1 SPERM-EGG FUSION PROTEIN LLCFC1 fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;cellular process#GO:0009987;single fertilization#GO:0007338;fertilization#GO:0009566;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609 GORGO|Ensembl=ENSGGOG00000003631.3|UniProtKB=G3QM42 G3QM42 NAT14 PTHR13947:SF51 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 14-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000026994.2|UniProtKB=A0A2I2ZSH6 A0A2I2ZSH6 NDOR1 PTHR19384:SF10 NITRIC OXIDE SYNTHASE-RELATED NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1 flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007113.3|UniProtKB=G3QW15 G3QW15 ZMYND10 PTHR13244:SF7 ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 10 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10 cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;inner dynein arm assembly#GO:0036159;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;plasma membrane bounded cell projection assembly#GO:0120031 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;centriolar satellite#GO:0034451;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000011317.3|UniProtKB=G3R6R6 G3R6R6 MRPS18B PTHR13329:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S18B SMALL RIBOSOMAL SUBUNIT PROTEIN MS40 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000002209.3|UniProtKB=G3QIG4 G3QIG4 HOXA1 PTHR45946:SF3 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-A1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000005420.3|UniProtKB=G3QRP6 G3QRP6 TTC4 PTHR46035:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 4 HSP70_HSP90 CO-CHAPERONE CNS1 HOMOLOG Hsp70 protein binding#GO:0030544;protein binding#GO:0005515;Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000034961.2|UniProtKB=G3SKG8 G3SKG8 GABRA3 PTHR18945:SF216 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-3 gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;neurotransmitter receptor activity#GO:0030594;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023 transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anatomical structure development#GO:0048856;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;system development#GO:0048731;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;chloride transport#GO:0006821;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;signaling#GO:0023052 cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell projection membrane#GO:0031253;dendrite#GO:0030425;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000010760.3|UniProtKB=G3R5C2 G3R5C2 ELF1 PTHR11849:SF156 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000040415.1|UniProtKB=A0A2I2Z0N4 A0A2I2Z0N4 PTHR11847:SF4 RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN EL15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000007548.3|UniProtKB=G3QX61 G3QX61 UBA1 PTHR10953:SF155 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 1 sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to stress#GO:0006950;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;response to stimulus#GO:0050896;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490;Ubiquitin proteasome pathway#P00060>E1#P01492 GORGO|Ensembl=ENSGGOG00000009831.3|UniProtKB=G3RSF7 G3RSF7 ZNF622 PTHR13182:SF8 ZINC FINGER PROTEIN 622 CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622 binding#GO:0005488;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085 preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009907.3|UniProtKB=G3R357 G3R357 KRTAP13-1 PTHR23262:SF246 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 13-1-RELATED structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000040854.1|UniProtKB=A0A2I2ZGW5 A0A2I2ZGW5 PTHR11346:SF15 GALECTIN PLACENTAL PROTEIN 13-LIKE binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000003573.3|UniProtKB=G3QLY6 G3QLY6 P2RX6 PTHR10125:SF21 P2X PURINOCEPTOR P2X PURINOCEPTOR 6 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;transport#GO:0006810 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000001843.3|UniProtKB=A0A2I2Z5M9 A0A2I2Z5M9 PAF1 PTHR23188:SF12 RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;chromatin binding#GO:0003682;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000023647.2|UniProtKB=G3SAV3 G3SAV3 PTHR11620:SF103 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003865.3|UniProtKB=A0A2I2Z497 A0A2I2Z497 PATE2 PTHR47884:SF1 PROSTATE AND TESTIS EXPRESSED PROTEIN 2 PROSTATE AND TESTIS EXPRESSED PROTEIN 2 GORGO|Ensembl=ENSGGOG00000027302.2|UniProtKB=A0A2I2ZCN8 A0A2I2ZCN8 ARHGAP35 PTHR46005:SF1 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 35 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556;regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cell projection organization#GO:0031344;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of axonogenesis#GO:0050770;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000008935.3|UniProtKB=G3R0P4 G3R0P4 LACC1 PTHR30616:SF5 UNCHARACTERIZED PROTEIN YFIH PURINE NUCLEOSIDE PHOSPHORYLASE LACC1 adenosine deaminase activity#GO:0004000;hydrolase activity#GO:0016787;pentosyltransferase activity#GO:0016763;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;glycosyltransferase activity#GO:0016757;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of innate immune response#GO:0045089;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376 peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000010884.3|UniProtKB=G3R5N3 G3R5N3 SOX6 PTHR45789:SF1 FI18025P1 TRANSCRIPTION FACTOR SOX-6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000002545.3|UniProtKB=G3QJC5 G3QJC5 BRWD1 PTHR16266:SF26 WD REPEAT DOMAIN 9 BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000022626.2|UniProtKB=G3RT55 G3RT55 LYG1 PTHR31698:SF5 LYSOZYME G FAMILY MEMBER LYSOZYME G-LIKE PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;lysozyme activity#GO:0003796;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000001706.3|UniProtKB=G3QH62 G3QH62 PHIP PTHR16266:SF4 WD REPEAT DOMAIN 9 PH-INTERACTING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011569.3|UniProtKB=A0A2I2ZPG1 A0A2I2ZPG1 LHFPL3 PTHR12489:SF13 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 3 PROTEIN nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025359.2|UniProtKB=A0A2I2YJL9 A0A2I2YJL9 PTHR10953:SF199 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 1 ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783 post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein sumoylation#GO:0016925;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016140.3|UniProtKB=G3S7W9 G3S7W9 OSBPL8 PTHR10972:SF216 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 8 small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934;alcohol binding#GO:0043178;steroid binding#GO:0005496;lipid binding#GO:0008289;cholesterol binding#GO:0015485 cytosol#GO:0005829;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000043368.1|UniProtKB=A0A2I2ZIR2 A0A2I2ZIR2 CHCHD5 PTHR47106:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 5 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 5 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967 GORGO|Ensembl=ENSGGOG00000037041.1|UniProtKB=A0A2I2ZCB2 A0A2I2ZCB2 PTHR10073:SF47 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH3 nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000039219.1|UniProtKB=A0A2I2ZU74 A0A2I2ZU74 RGSL1 PTHR47079:SF1 REGULATOR OF G-PROTEIN SIGNALING PROTEIN-LIKE REGULATOR OF G PROTEIN SIGNALING PROTEIN-LIKE GORGO|Ensembl=ENSGGOG00000013448.3|UniProtKB=G3RC91 G3RC91 C4H5orf47 PTHR38655:SF1 SIMILAR TO RIKEN CDNA 4930524B15 SIMILAR TO HUMAN CHROMOSOME 5 OPEN READING FRAME 47 GORGO|Ensembl=ENSGGOG00000015795.3|UniProtKB=G3RIA9 G3RIA9 MYG1 PTHR11215:SF1 METAL DEPENDENT HYDROLASE - RELATED MYG1 EXONUCLEASE hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000000510.3|UniProtKB=G3RM44 G3RM44 COL17A1 PTHR24023:SF891 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVII) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell-substrate junction#GO:0030055;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000010144.3|UniProtKB=G3R3R7 G3R3R7 FLT3LG PTHR11032:SF1 SL CYTOKINE FMS-RELATED TYROSINE KINASE 3 LIGAND kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;receptor tyrosine kinase binding#GO:0030971 positive regulation of cell population proliferation#GO:0008284;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;extracellular region#GO:0005576 intercellular signal molecule#PC00207;cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000026131.2|UniProtKB=G3SCS6 G3SCS6 PTHR21568:SF0 TRNA PSEUDOURIDINE SYNTHASE PUS10 TRNA PSEUDOURIDINE SYNTHASE PUS10 isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866 negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;macromolecule modification#GO:0043412;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;primary miRNA processing#GO:0031053;tRNA processing#GO:0008033;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA modification#GO:0009451;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011111.3|UniProtKB=G3R684 G3R684 PLAC9 PTHR37355:SF1 PLACENTA-SPECIFIC PROTEIN 9 PLACENTA-SPECIFIC PROTEIN 9 GORGO|Ensembl=ENSGGOG00000005293.3|UniProtKB=G3QRD7 G3QRD7 ZSCAN4 PTHR23226:SF88 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000042495.1|UniProtKB=G3QU24 G3QU24 LOC101141138 PTHR48001:SF195 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7C1 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007029.3|UniProtKB=G3QVV1 G3QVV1 SLC44A5 PTHR12385:SF42 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000039899.1|UniProtKB=A0A2I2Z3D0 A0A2I2Z3D0 LOC101135168 PTHR23045:SF9 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A-RELATED transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002390.3|UniProtKB=A0A2I2ZV21 A0A2I2ZV21 PTHR22850:SF193 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP4-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004822.3|UniProtKB=G3S9C6 G3S9C6 ZDHHC19 PTHR22883:SF326 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC19 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 developmental maturation#GO:0021700;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization#GO:0051234;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000014703.3|UniProtKB=G3S271 G3S271 PHF8 PTHR23123:SF11 PHD/F-BOX CONTAINING PROTEIN HISTONE LYSINE DEMETHYLASE PHF8 protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone demethylase activity#GO:0032452 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000008631.3|UniProtKB=G3QZX4 G3QZX4 VWA3A PTHR46478:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3A GORGO|Ensembl=ENSGGOG00000006266.3|UniProtKB=G3QTU7 G3QTU7 ARHGAP24 PTHR15228:SF19 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 24 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 response to wounding#GO:0009611;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;tissue development#GO:0009888;cell migration#GO:0016477;epithelium development#GO:0060429;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;negative regulation of cellular component organization#GO:0051129;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cell projection assembly#GO:0060491;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;cellular process#GO:0009987;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;morphogenesis of an epithelium#GO:0002009;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;wound healing#GO:0042060;negative regulation of intracellular signal transduction#GO:1902532 anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000001883.3|UniProtKB=G3QHM3 G3QHM3 CRACDL PTHR47743:SF1 KIAA1210 / KIAA1211 FAMILY MEMBER CRACD-LIKE PROTEIN GORGO|Ensembl=ENSGGOG00000036519.1|UniProtKB=A0A2I2YFM5 A0A2I2YFM5 PTHR11955:SF139 FATTY ACID BINDING PROTEIN LIPOCALIN_CYTOSOLIC FATTY-ACID BINDING DOMAIN-CONTAINING PROTEIN fatty acid binding#GO:0005504;lipid binding#GO:0008289;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177 lipid transport#GO:0006869;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000013092.3|UniProtKB=G3RBD1 G3RBD1 PTHR22802:SF445 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 17, MEMBER A binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000004908.3|UniProtKB=G3QQE3 G3QQE3 TFDP1 PTHR12548:SF4 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000005005.3|UniProtKB=G3QQP0 G3QQP0 TCIRG1 PTHR11629:SF21 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 3 binding#GO:0005488;enzyme binding#GO:0019899;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;autophagosome maturation#GO:0097352;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;monoatomic ion transmembrane transport#GO:0034220;macroautophagy#GO:0016236;biological regulation#GO:0065007;localization#GO:0051179;monoatomic cation transport#GO:0006812;vacuole organization#GO:0007033;regulation of pH#GO:0006885;organelle assembly#GO:0070925;regulation of intracellular pH#GO:0051453;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;homeostatic process#GO:0042592;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;cellular component assembly#GO:0022607;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;transmembrane transport#GO:0055085;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;apical plasma membrane#GO:0016324;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;proton-transporting two-sector ATPase complex#GO:0016469;apical part of cell#GO:0045177 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000037184.1|UniProtKB=A0A2I2ZVJ0 A0A2I2ZVJ0 TMEM18 PTHR22593:SF2 TRANSMEMBRANE PROTEIN 18 TRANSMEMBRANE PROTEIN 18 nucleus#GO:0005634;organelle envelope#GO:0031967;membrane#GO:0016020;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000013004.3|UniProtKB=G3RB46 G3RB46 ATMIN PTHR46664:SF2 ATM INTERACTOR ATM INTERACTOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000016496.3|UniProtKB=G3S0Q8 G3S0Q8 C5H6orf62 PTHR28336:SF1 BA1-643 SIMILAR TO CDNA SEQUENCE BC005537 GORGO|Ensembl=ENSGGOG00000024415.2|UniProtKB=G3S8Y5 G3S8Y5 LOC101148837 PTHR24242:SF379 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000011621.3|UniProtKB=G3R7L4 G3R7L4 PDCD11 PTHR23270:SF10 PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5 PROTEIN RRP5 HOMOLOG snoRNA binding#GO:0030515;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005301.3|UniProtKB=G3QRE1 G3QRE1 ZNF665 PTHR24377:SF1043 IP01015P-RELATED ZINC FINGER PROTEIN 160-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000037731.1|UniProtKB=A0A2I2YAR1 A0A2I2YAR1 USP11 PTHR21646:SF29 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 11 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000015468.3|UniProtKB=G3RHH6 G3RHH6 EFCAB6 PTHR20875:SF2 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000002176.3|UniProtKB=A0A2I2YQJ3 A0A2I2YQJ3 BET1 PTHR12791:SF53 GOLGI SNARE BET1-RELATED BET1 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 vesicle fusion#GO:0006906;cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle organization#GO:0006996;membrane fusion#GO:0061025;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 membrane#GO:0016020;membrane protein complex#GO:0098796;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 SNARE protein#PC00034 GORGO|Ensembl=ENSGGOG00000005399.3|UniProtKB=G3QRM6 G3QRM6 MAGEB3 PTHR11736:SF53 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B3 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039376.1|UniProtKB=A0A2I2YVW3 A0A2I2YVW3 IFNAR2 PTHR20859:SF84 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON ALPHA_BETA RECEPTOR 2 molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to other organism#GO:0051707;biological regulation#GO:0065007;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to peptide#GO:1901652;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;cytokine-mediated signaling pathway#GO:0019221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015705.3|UniProtKB=G3RI34 G3RI34 IGSF9B PTHR10075:SF114 BASIGIN RELATED PROTEIN TURTLE HOMOLOG B cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000041120.1|UniProtKB=A0A2I2ZSV6 A0A2I2ZSV6 PTHR19433:SF117 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 13-2 response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014774.3|UniProtKB=A0A2I2YCF8 A0A2I2YCF8 PHACTR3 PTHR12751:SF7 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 3 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000010368.3|UniProtKB=G3R4B9 G3R4B9 MPPED2 PTHR12905:SF13 METALLOPHOSPHOESTERASE METALLOPHOSPHOESTERASE MPPED2 cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 GORGO|Ensembl=ENSGGOG00000016374.3|UniProtKB=G3RQL8 G3RQL8 ZNF514 PTHR23226:SF457 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 514 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002558.3|UniProtKB=G3QJC8 G3QJC8 MMAA PTHR23408:SF3 METHYLMALONYL-COA MUTASE METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 mutase#PC00160 GORGO|Ensembl=ENSGGOG00000005139.3|UniProtKB=Q95LF9 Q95LF9 ACKR1 PTHR14181:SF1 DUFFY ANTIGEN/CHEMOKINE RECEPTOR ATYPICAL CHEMOKINE RECEPTOR 1 cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;defense response#GO:0006952;response to stress#GO:0006950;inflammatory response#GO:0006954 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013511.3|UniProtKB=G3RCG0 G3RCG0 PTHR23120:SF18 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 8 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000023091.2|UniProtKB=G3S2X3 G3S2X3 BBS10 PTHR14667:SF2 BARDET-BIEDL SYNDROME 10 PROTEIN BBSOME COMPLEX ASSEMBLY PROTEIN BBS10 chaperone-mediated protein complex assembly#GO:0051131;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607 GORGO|Ensembl=ENSGGOG00000006496.3|UniProtKB=G3QUF2 G3QUF2 CNTFR PTHR23036:SF21 CYTOKINE RECEPTOR CILIARY NEUROTROPHIC FACTOR RECEPTOR SUBUNIT ALPHA cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013956.3|UniProtKB=A0A2I2YFE6 A0A2I2YFE6 TMEM71 PTHR35255:SF1 TRANSMEMBRANE PROTEIN 71 TRANSMEMBRANE PROTEIN 71 GORGO|Ensembl=ENSGGOG00000003829.3|UniProtKB=G3QML8 G3QML8 PPM1H PTHR13832:SF287 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1H hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000014019.3|UniProtKB=G3RDR8 G3RDR8 DCLK2 PTHR24347:SF376 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000016065.3|UniProtKB=G3RJ15 G3RJ15 LPA PTHR24261:SF2 PLASMINOGEN-RELATED LIPOPROTEIN(A) catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;binding#GO:0005488;signaling receptor binding#GO:0005102;hydrolase activity#GO:0016787;protein binding#GO:0005515 metabolic process#GO:0008152;regulation of response to stress#GO:0080134;negative regulation of blood coagulation#GO:0030195;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;negative regulation of response to wounding#GO:1903035;regulation of response to wounding#GO:1903034;negative regulation of wound healing#GO:0061045;cellular process#GO:0009987;regulation of hemostasis#GO:1900046;regulation of coagulation#GO:0050818;fibrinolysis#GO:0042730;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;proteolysis#GO:0006508;negative regulation of hemostasis#GO:1900047;protein metabolic process#GO:0019538;negative regulation of coagulation#GO:0050819;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;regulation of wound healing#GO:0061041 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein modifying enzyme#PC00260;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000023764.2|UniProtKB=G3RWI3 G3RWI3 PTHR24180:SF44 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED SUBFAMILY NOT NAMED positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 kinase inhibitor#PC00139;kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000043251.1|UniProtKB=A0A2I2Z3D3 A0A2I2Z3D3 PTHR23232:SF178 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN 5-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000042859.1|UniProtKB=A0A2I2Z7R7 A0A2I2Z7R7 PTHR23267:SF399 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015351.3|UniProtKB=G3RH59 G3RH59 GNS PTHR43108:SF5 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-ACETYLGLUCOSAMINE-6-SULFATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;glycoprotein metabolic process#GO:0009100;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000016428.3|UniProtKB=G3RJY0 G3RJY0 ECD PTHR13060:SF0 SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2 PROTEIN ECDYSONELESS HOMOLOG transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000023307.2|UniProtKB=A0A2I2Y422 A0A2I2Y422 ZNF25 PTHR24381:SF62 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 25 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000041336.1|UniProtKB=A0A2I2ZXH4 A0A2I2ZXH4 PTHR23159:SF16 CENTROSOMAL PROTEIN 2 CILIARY ROOTLET COILED-COIL PROTEIN 2 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000023127.2|UniProtKB=G3SHA3 G3SHA3 PTPRZ1 PTHR19134:SF461 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;central nervous system development#GO:0007417;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;gliogenesis#GO:0042063;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;oligodendrocyte differentiation#GO:0048709;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000012860.3|UniProtKB=G3RAR3 G3RAR3 IER5 PTHR15895:SF12 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 5 PROTEIN GORGO|Ensembl=ENSGGOG00000005410.3|UniProtKB=G3QRN6 G3QRN6 GRPEL2 PTHR21237:SF10 GRPE PROTEIN GRPE PROTEIN HOMOLOG 2, MITOCHONDRIAL nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000000348.3|UniProtKB=G3QDL8 G3QDL8 TPPP PTHR12932:SF18 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of protein polymerization#GO:0032273;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;microtubule bundle formation#GO:0001578;positive regulation of cellular component organization#GO:0051130;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000026845.2|UniProtKB=G3SJS6 G3SJS6 PTHR10504:SF17 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BPI FOLD-CONTAINING FAMILY C PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000004834.3|UniProtKB=G3QQ74 G3QQ74 ALG14 PTHR12154:SF4 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000039671.1|UniProtKB=A0A2I2Z7S6 A0A2I2Z7S6 PTHR13351:SF6 RENIN RECEPTOR RENIN RECEPTOR regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000123.3|UniProtKB=G3QD19 G3QD19 CCDC60 PTHR34754:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 60 COILED-COIL DOMAIN-CONTAINING PROTEIN 60 GORGO|Ensembl=ENSGGOG00000000900.3|UniProtKB=G3QF25 G3QF25 ALDH9A1 PTHR11699:SF228 ALDEHYDE DEHYDROGENASE-RELATED 4-TRIMETHYLAMINOBUTYRALDEHYDE DEHYDROGENASE aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;carnitine metabolic process#GO:0009437;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000013223.3|UniProtKB=A0A2I2YKR8 A0A2I2YKR8 NAP1L4 PTHR11875:SF75 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 4 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 cellular component assembly#GO:0022607;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000003025.3|UniProtKB=G3QKK0 G3QKK0 IVNS1ABP PTHR24412:SF396 KELCH PROTEIN INFLUENZA VIRUS NS1A-BINDING PROTEIN ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002522.3|UniProtKB=G3QJA1 G3QJA1 FBXL2 PTHR13382:SF40 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B F-BOX_LRR-REPEAT PROTEIN 2 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000015803.3|UniProtKB=G3RIB7 G3RIB7 ZAR1L PTHR31054:SF5 ZYGOTE ARREST PROTEIN 1-LIKE ISOFORM X1 PROTEIN ZAR1-LIKE RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 oogenesis#GO:0048477;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of translation#GO:0017148;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cell maturation#GO:0048469;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;developmental maturation#GO:0021700;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004330.3|UniProtKB=G3QNX0 G3QNX0 LYPLA2 PTHR10655:SF13 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 2 catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;carboxylic ester hydrolase activity#GO:0052689;thiolester hydrolase activity#GO:0016790;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;biological regulation#GO:0065007;negative regulation of protein transport#GO:0051224;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;lipid metabolic process#GO:0006629;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of transport#GO:0051051;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 lipase#PC00143;phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000010060.3|UniProtKB=G3RRG8 G3RRG8 LOC101149677 PTHR46160:SF3 ALPHA-TECTORIN-RELATED ALPHA-TECTORIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 GORGO|Gene=FUT6|UniProtKB=Q8HYJ6 Q8HYJ6 FUT6 PTHR11929:SF227 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE FUT6 alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000008591.3|UniProtKB=G3S0C7 G3S0C7 HACE1 PTHR11254:SF363 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HACE1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;modification-dependent protein catabolic process#GO:0019941;Golgi organization#GO:0007030;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;nucleus#GO:0005634;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002991.3|UniProtKB=G3QKG5 G3QKG5 KPLCE PTHR35022:SF28 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN PROTEIN KPLCE GORGO|Ensembl=ENSGGOG00000010969.3|UniProtKB=A0A2I2ZBY2 A0A2I2ZBY2 RGS7 PTHR45746:SF7 LP21163P REGULATOR OF G PROTEIN SIGNALING 7 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 GORGO|Ensembl=ENSGGOG00000000447.3|UniProtKB=G3QDW0 G3QDW0 ALG1 PTHR13036:SF1 BETA1,4 MANNOSYLTRANSFERASE CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000013748.3|UniProtKB=G3RD17 G3RD17 PTHR24098:SF14 OUTER SEGMENT 5 TRIPARTITE MOTIF-CONTAINING PROTEIN 59 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intraciliary transport particle B#GO:0030992;intraciliary transport particle#GO:0030990 GORGO|Ensembl=ENSGGOG00000004086.3|UniProtKB=G3QN99 G3QN99 MAP3K3 PTHR24361:SF656 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;FGF signaling pathway#P00021>MEKK1-5#P00634;B cell activation#P00010>MEKK#P00369;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Integrin signalling pathway#P00034>ERK#P00907 GORGO|Ensembl=ENSGGOG00000016223.3|UniProtKB=G3RJE3 G3RJE3 ALKBH5 PTHR32074:SF2 RNA DEMETHYLASE ALKBH5 RNA DEMETHYLASE ALKBH5 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;dioxygenase activity#GO:0051213 negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000014234.3|UniProtKB=G3REB0 G3REB0 PTPRR PTHR46198:SF2 PROTEIN-TYROSINE-PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE R enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000027635.2|UniProtKB=G3RYA7 G3RYA7 PTHR47440:SF1 RIKEN CDNA A430078G23 GENE RHO_RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR 18 GORGO|Ensembl=ENSGGOG00000005063.3|UniProtKB=A0A2I2ZES7 A0A2I2ZES7 SCN1B PTHR10546:SF2 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL REGULATORY SUBUNIT BETA-1 ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;molecular function regulator activity#GO:0098772;binding#GO:0005488;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247 establishment of localization#GO:0051234;cardiac muscle cell contraction#GO:0086003;system process#GO:0003008;heart contraction#GO:0060047;regulation of system process#GO:0044057;muscle contraction#GO:0006936;transport#GO:0006810;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;actin filament-based movement#GO:0030048;monoatomic cation transport#GO:0006812;localization#GO:0051179;circulatory system process#GO:0003013;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;actin-mediated cell contraction#GO:0070252;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;regulation of heart contraction#GO:0008016;regulation of membrane potential#GO:0042391;cardiac muscle cell action potential involved in contraction#GO:0086002;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;action potential#GO:0001508;regulation of biological process#GO:0050789;muscle system process#GO:0003012;heart process#GO:0003015;sodium ion transport#GO:0006814 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;sodium channel complex#GO:0034706;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000002168.3|UniProtKB=G3QID2 G3QID2 IFT81 PTHR15614:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intraciliary transport particle B#GO:0030992;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000003045.3|UniProtKB=G3QKM6 G3QKM6 PTHR24092:SF98 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IB ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 lipid localization#GO:0010876;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;cell differentiation#GO:0030154;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cell development#GO:0048468;developmental process#GO:0032502;neuron differentiation#GO:0030182;transport#GO:0006810;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;multicellular organismal process#GO:0032501;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;nervous system development#GO:0007399 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000028345.2|UniProtKB=G3S1R2 G3S1R2 PROSER2 PTHR16095:SF9 TRANSMEMBRANE PROTEIN 143 FAMILY MEMBER PROLINE AND SERINE-RICH PROTEIN 2 GORGO|Ensembl=ENSGGOG00000001838.3|UniProtKB=G3S0J7 G3S0J7 LOC109024875 PTHR38140:SF4 KERATIN-ASSOCIATED PROTEIN 19-3-RELATED KERATIN-ASSOCIATED PROTEIN 19-5 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000003896.3|UniProtKB=G3S3N7 G3S3N7 KCNC2 PTHR11537:SF172 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL KCNC2 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;action potential#GO:0001508;metal ion transport#GO:0030001 neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;axon terminus#GO:0043679;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;neuron projection terminus#GO:0044306;neuronal cell body#GO:0043025;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;neuron projection#GO:0043005;presynapse#GO:0098793;cell leading edge#GO:0031252;protein-containing complex#GO:0032991;leading edge membrane#GO:0031256;postsynaptic membrane#GO:0045211;cell projection membrane#GO:0031253;cell body#GO:0044297;postsynapse#GO:0098794;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000010851.3|UniProtKB=G3RSJ7 G3RSJ7 EDAR PTHR12120:SF9 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER EDAR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000037180.1|UniProtKB=A0A2I2ZEX0 A0A2I2ZEX0 PTHR12080:SF97 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;leukocyte activation#GO:0045321;T cell activation#GO:0042110;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;immune system process#GO:0002376;cell activation#GO:0001775 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000002528.3|UniProtKB=G3QJA2 G3QJA2 ANKRD33B PTHR24173:SF1 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 33B scaffold/adaptor protein#PC00226 GORGO|Gene=FSHB|UniProtKB=A1BN60 A1BN60 FSHB PTHR11515:SF17 GLYCOPROTEIN HORMONE BETA CHAIN FOLLITROPIN SUBUNIT BETA signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546 developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;sex differentiation#GO:0007548;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;gonad development#GO:0008406;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;rhythmic process#GO:0048511;anatomical structure development#GO:0048856;cell communication#GO:0007154;multicellular organismal reproductive process#GO:0048609;reproductive system development#GO:0061458;system development#GO:0048731;female gonad development#GO:0008585;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;reproductive structure development#GO:0048608;reproductive process#GO:0022414;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>3' FSHbeta#G06900;Gonadotropin-releasing hormone receptor pathway#P06664>5' FSHbeta#G06904;Gonadotropin-releasing hormone receptor pathway#P06664>FSHbeta#P06809;Gonadotropin-releasing hormone receptor pathway#P06664>FSHbeta#G06678 GORGO|Ensembl=ENSGGOG00000004870.3|UniProtKB=A0A2I2YTE8 A0A2I2YTE8 ATF6B PTHR46164:SF2 ATF6, ISOFORM C CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-6 BETA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;response to unfolded protein#GO:0006986;regulation of DNA-templated transcription#GO:0006355;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 Apoptosis signaling pathway#P00006>ATF#P00302 GORGO|Ensembl=ENSGGOG00000002160.3|UniProtKB=G3S734 G3S734 PLEK2 PTHR12092:SF2 PLECKSTRIN PLECKSTRIN-2 cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000003782.4|UniProtKB=G3QMH7 G3QMH7 ZRANB3 PTHR45766:SF3 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677 replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000024645.2|UniProtKB=A0A2I2Z9W7 A0A2I2Z9W7 C2H3orf52 PTHR14636:SF1 TPA-INDUCED TRANSMEMBRANE PROTEIN TPA-INDUCED TRANSMEMBRANE PROTEIN GORGO|Ensembl=ENSGGOG00000009883.3|UniProtKB=G3R338 G3R338 IGFBP4 PTHR11551:SF7 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 4 binding#GO:0005488;protein binding#GO:0005515;growth factor binding#GO:0019838 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000037007.1|UniProtKB=A0A2I2Z8B7 A0A2I2Z8B7 ZNF12 PTHR24377:SF1023 IP01015P-RELATED ZINC FINGER PROTEIN 12 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013999.3|UniProtKB=G3RDP5 G3RDP5 CLDN1 PTHR12002:SF92 CLAUDIN CLAUDIN-1 virus receptor activity#GO:0001618;protein binding#GO:0005515;binding#GO:0005488 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000008051.3|UniProtKB=G3SID5 G3SID5 LCMT1 PTHR13600:SF33 LEUCINE CARBOXYL METHYLTRANSFERASE LEUCINE CARBOXYL METHYLTRANSFERASE 1 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;regulation of response to stimulus#GO:0048583;regulation of chromosome segregation#GO:0051983;regulation of chromosome separation#GO:1905818;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of nuclear division#GO:0051783;regulation of signal transduction#GO:0009966;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000024674.2|UniProtKB=G3S2W1 G3S2W1 CLDN3 PTHR12002:SF112 CLAUDIN CLAUDIN-3 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;establishment of localization#GO:0051234;paracellular transport#GO:0160184;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000012435.3|UniProtKB=G3R9P3 G3R9P3 POU4F3 PTHR11636:SF43 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000004874.3|UniProtKB=A0A2I2Y6C4 A0A2I2Y6C4 ABHD5 PTHR42886:SF34 RE40534P-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 transferase activity#GO:0016740;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 organophosphate biosynthetic process#GO:0090407;positive regulation of metabolic process#GO:0009893;regulation of lipid metabolic process#GO:0019216;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;phosphorus metabolic process#GO:0006793;regulation of lipid catabolic process#GO:0050994;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;organophosphate metabolic process#GO:0019637;regulation of primary metabolic process#GO:0080090;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007529.3|UniProtKB=G3SFF0 G3SFF0 NETO2 PTHR24251:SF26 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE PROTEIN 2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of localization#GO:0032879;intracellular protein localization#GO:0008104;protein localization to synapse#GO:0035418;protein localization to cell periphery#GO:1990778;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;biological regulation#GO:0065007;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to cell junction#GO:1902414;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657 postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cell junction#GO:0030054 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000007270.3|UniProtKB=G3S6N3 G3S6N3 KLHDC3 PTHR46461:SF1 KELCH DOMAIN-CONTAINING PROTEIN 3 KELCH DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;chromatin binding#GO:0003682 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000027670.2|UniProtKB=A0A2I2Z4T1 A0A2I2Z4T1 PTHR24173:SF67 ANKYRIN REPEAT CONTAINING FEM-1 HOMOLOG A ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of response to stress#GO:0080134;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stimulus#GO:0048583;catabolic process#GO:0009056;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013230.3|UniProtKB=G3RBP4 G3RBP4 CBY1 PTHR12504:SF3 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031 organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane translocase complex#GO:0005742;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003651.3|UniProtKB=G3QM65 G3QM65 SLC6A9 PTHR11616:SF263 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 1 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;symporter activity#GO:0015293 glycine transport#GO:0015816;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;import into cell#GO:0098657;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000008724.3|UniProtKB=G3R052 G3R052 EBNA1BP2 PTHR13028:SF0 RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED RRNA-PROCESSING PROTEIN EBP2-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687 GORGO|Ensembl=ENSGGOG00000009423.3|UniProtKB=A0A2I2YY02 A0A2I2YY02 BIN2 PTHR46514:SF1 AMPHIPHYSIN BRIDGING INTEGRATOR 2 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;endocytosis#GO:0006897;cell projection organization#GO:0030030;plasma membrane organization#GO:0007009;localization#GO:0051179;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;phagocytosis#GO:0006909;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;membrane invagination#GO:0010324;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;protein-containing complex organization#GO:0043933 cell periphery#GO:0071944;actin-based cell projection#GO:0098858;membrane#GO:0016020;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000000265.3|UniProtKB=G3QDE6 G3QDE6 CUTA PTHR23419:SF1 DIVALENT CATION TOLERANCE CUTA-RELATED PROTEIN CUTA cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;copper ion binding#GO:0005507;ion binding#GO:0043167 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000001991.3|UniProtKB=G3SDL0 G3SDL0 DCTN2 PTHR15346:SF0 DYNACTIN SUBUNIT DYNACTIN SUBUNIT 2 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal adaptor activity#GO:0008093 organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell cycle process#GO:0022402;nuclear migration#GO:0007097;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000002759.3|UniProtKB=G3QJW5 G3QJW5 DDIT4 PTHR12478:SF7 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 DNA DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN protein binding#GO:0005515;binding#GO:0005488 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;response to hypoxia#GO:0001666;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;response to abiotic stimulus#GO:0009628;response to oxygen levels#GO:0070482;negative regulation of biological process#GO:0048519;response to decreased oxygen levels#GO:0036293;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007 GORGO|Ensembl=ENSGGOG00000044134.1|UniProtKB=A0A2I2Y7W3 A0A2I2Y7W3 PTHR11426:SF228 HISTONE H3 HISTONE H3.3 cellular component assembly#GO:0022607;chromosome localization#GO:0050000;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;organelle fission#GO:0048285;kinetochore organization#GO:0051383;localization#GO:0051179;organelle localization#GO:0051640;nuclear division#GO:0000280;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 GORGO|Ensembl=ENSGGOG00000004705.3|UniProtKB=G3QPV2 G3QPV2 SLC25A29 PTHR45624:SF61 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;intracellular transport#GO:0046907;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;cellular localization#GO:0051641;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023724.2|UniProtKB=A0A2I2Z2Z2 A0A2I2Z2Z2 METTL1 PTHR23417:SF23 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000001028.3|UniProtKB=G3QFE2 G3QFE2 PTHR19850:SF36 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-5 signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095;G-protein#PC00020;heterotrimeric G-protein#PC00117 Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta5L#P00748;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;PI3 kinase pathway#P00048>Gbetagamma#P01188;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085 GORGO|Ensembl=ENSGGOG00000014254.3|UniProtKB=G3SDU1 G3SDU1 PTHR23507:SF9 ZGC:174356 LYSOSOMAL PROTON-COUPLED STEROID CONJUGATE AND BILE ACID SYMPORTER SLC46A3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;vacuolar transmembrane transport#GO:0034486;establishment of localization#GO:0051234;localization#GO:0051179 lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774 GORGO|Ensembl=ENSGGOG00000003977.4|UniProtKB=G3QN01 G3QN01 TAF4B PTHR15138:SF17 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4B nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000042309.1|UniProtKB=A0A2I2YZ97 A0A2I2YZ97 CMTM6 PTHR22776:SF25 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 6 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response#GO:0006955;immune system process#GO:0002376 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737;recycling endosome#GO:0055037;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037757.1|UniProtKB=A0A2I2ZBC3 A0A2I2ZBC3 PTHR25952:SF255 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN GORGO|Ensembl=ENSGGOG00000014810.3|UniProtKB=G3RFS3 G3RFS3 LOXL1 PTHR45817:SF8 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 1 catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007230.3|UniProtKB=G3S2E4 G3S2E4 YAF2 PTHR12920:SF2 RYBP AND YAF2-RELATED YY1-ASSOCIATED FACTOR 2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000000404.3|UniProtKB=A0A2I2ZW83 A0A2I2ZW83 CEP152 PTHR10337:SF6 SHC TRANSFORMING PROTEIN CENTROSOMAL PROTEIN OF 152 KDA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000024064.2|UniProtKB=G3SG70 G3SG70 CCT5 PTHR11353:SF186 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT EPSILON metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058 cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000006498.3|UniProtKB=G3QUF7 G3QUF7 KIAA1755 PTHR45845:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED KIAA1755 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000015413.3|UniProtKB=G3RHB7 G3RHB7 OTOR PTHR47146:SF1 OTORAPLIN OTORAPLIN multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;tissue development#GO:0009888;skeletal system morphogenesis#GO:0048705;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;cartilage development#GO:0051216;connective tissue development#GO:0061448;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 GORGO|Ensembl=ENSGGOG00000026059.2|UniProtKB=G3RPE7 G3RPE7 LOC101146243 PTHR26453:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000022839.2|UniProtKB=A0A2I2YLB3 A0A2I2YLB3 PTHR10807:SF34 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR6 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;lipid modification#GO:0030258;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000013300.3|UniProtKB=G3RBV6 G3RBV6 EDN1 PTHR13874:SF10 ENDOTHELIN ENDOTHELIN-1 hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855 regulation of blood pressure#GO:0008217;monoatomic ion homeostasis#GO:0050801;regulation of systemic arterial blood pressure#GO:0003073;positive regulation of biological process#GO:0048518;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;muscle contraction#GO:0006936;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;system process#GO:0003008;cellular homeostasis#GO:0019725;regulation of smooth muscle contraction#GO:0006940;intracellular monoatomic ion homeostasis#GO:0006873;regulation of muscle system process#GO:0090257;muscle system process#GO:0003012;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;homeostatic process#GO:0042592;regulation of muscle contraction#GO:0006937;calcium ion homeostasis#GO:0055074;circulatory system process#GO:0003013;inorganic ion homeostasis#GO:0098771;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Endothelin signaling pathway#P00019>Pre-pro ET1-4#P00576;Endothelin signaling pathway#P00019>Big ET1-4#P00574;Endothelin signaling pathway#P00019>Pro ET1-4#P00571;Endothelin signaling pathway#P00019>ET1-4#P00588 GORGO|Ensembl=ENSGGOG00000010021.3|UniProtKB=G3R3F3 G3R3F3 LOC109028100 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000005960.3|UniProtKB=G3RTR7 G3RTR7 RSRC2 PTHR22426:SF2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 GORGO|Ensembl=ENSGGOG00000012606.3|UniProtKB=A0A2I2ZFH8 A0A2I2ZFH8 PSMG4 PTHR33559:SF1 PROTEASOME ASSEMBLY CHAPERONE 4 PROTEASOME ASSEMBLY CHAPERONE 4 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000006962.3|UniProtKB=G3RPD3 G3RPD3 NOSTRIN PTHR14167:SF31 SH3 DOMAIN-CONTAINING NOSTRIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000036801.1|UniProtKB=A0A2I2ZCM0 A0A2I2ZCM0 PTHR11691:SF64 TYPE I INTERFERON INTERFERON ALPHA-1-RELATED protein binding#GO:0005515;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 immune effector process#GO:0002252;natural killer cell activation#GO:0030101;leukocyte activation involved in immune response#GO:0002366;cell surface receptor signaling pathway#GO:0007166;humoral immune response#GO:0006959;B cell activation#GO:0042113;cellular process#GO:0009987;lymphocyte activation involved in immune response#GO:0002285;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;T cell activation involved in immune response#GO:0002286;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;lymphocyte activation#GO:0046649;B cell activation involved in immune response#GO:0002312;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;response to peptide#GO:1901652;cell activation involved in immune response#GO:0002263;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;interferon superfamily#PC00127 GORGO|Ensembl=ENSGGOG00000039155.1|UniProtKB=A0A2I2ZWH3 A0A2I2ZWH3 PTHR22850:SF194 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP4-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;PcG protein complex#GO:0031519;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000025733.2|UniProtKB=G3S4Z7 G3S4Z7 PARP15 PTHR14453:SF99 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP15 transferase activity#GO:0016740;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;glycosyltransferase activity#GO:0016757;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transcription regulator activity#GO:0140110;pentosyltransferase activity#GO:0016763 negative regulation of gene expression#GO:0010629;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biological process#GO:0048519;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of biological process#GO:0050789;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000037850.1|UniProtKB=A0A2I2ZJB5 A0A2I2ZJB5 PTHR19375:SF597 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;ribonucleoside triphosphate phosphatase activity#GO:0017111;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887 cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;localization#GO:0051179;protein refolding#GO:0042026;endocytosis#GO:0006897;protein folding#GO:0006457;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;clathrin-dependent endocytosis#GO:0072583;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;metabolic process#GO:0008152;transport#GO:0006810;protein maturation#GO:0051604;vesicle-mediated transport#GO:0016192;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 GORGO|Ensembl=ENSGGOG00000007866.3|UniProtKB=G3QXX1 G3QXX1 SLC23A2 PTHR11119:SF33 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;sugar transmembrane transporter activity#GO:0051119;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;carboxylic acid transmembrane transport#GO:1905039;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000041610.1|UniProtKB=A0A2I2ZSS0 A0A2I2ZSS0 TCEANC2 PTHR11477:SF14 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A N-TERMINAL AND CENTRAL DOMAIN-CONTAINING PROTEIN 2 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009655.3|UniProtKB=A0A2I2Y3A1 A0A2I2Y3A1 HSPA4 PTHR45639:SF6 HSC70CB, ISOFORM G-RELATED HEAT SHOCK 70 KDA PROTEIN 4 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Hsp70 family chaperone#PC00027;chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000023807.2|UniProtKB=G3SJX2 G3SJX2 SNX31 PTHR12431:SF15 SORTING NEXIN 17 AND 27 SORTING NEXIN-31 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;localization within membrane#GO:0051668 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000036536.1|UniProtKB=G3RL08 G3RL08 KRT31 PTHR23239:SF97 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA1 structural molecule activity#GO:0005198 morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cellular process#GO:0009987;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000002913.3|UniProtKB=G3QK98 G3QK98 LOC101142758 PTHR46237:SF2 CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER CYTOCHROME B5 REDUCTASE 4 catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 superoxide metabolic process#GO:0006801;cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000028424.2|UniProtKB=A0A2I2ZTZ9 A0A2I2ZTZ9 PTHR11581:SF35 30S/40S RIBOSOMAL PROTEIN S4 SMALL RIBOSOMAL SUBUNIT PROTEIN ES4, X ISOFORM structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004686.3|UniProtKB=G3SAZ7 G3SAZ7 C12H2orf78 PTHR31466:SF1 GENE 5591-RELATED RIKEN CDNA 4930433I11 GENE GORGO|Ensembl=ENSGGOG00000022414.2|UniProtKB=A0A2I2YIN4 A0A2I2YIN4 PTHR46002:SF7 EG:114D9.1 PROTEIN-RELATED EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of calcineurin-NFAT signaling cascade#GO:0070884;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000010072.3|UniProtKB=G3R3K2 G3R3K2 DNASE1L3 PTHR11371:SF32 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE GAMMA catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;DNA binding#GO:0003677;nuclease activity#GO:0004518 nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;developmental process#GO:0032502;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;apoptotic process#GO:0006915;cell death#GO:0008219;execution phase of apoptosis#GO:0097194;catabolic process#GO:0009056;cell differentiation#GO:0030154;cell development#GO:0048468;DNA catabolic process#GO:0006308;anatomical structure development#GO:0048856;cellular component disassembly#GO:0022411 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 endodeoxyribonuclease#PC00093 GORGO|Ensembl=ENSGGOG00000042815.1|UniProtKB=A0A2I2Y536 A0A2I2Y536 KDELR2 PTHR10585:SF37 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR 2 signal sequence receptor activity#GO:0005048 intracellular protein localization#GO:0008104;cellular localization#GO:0051641;protein localization to organelle#GO:0033365;localization#GO:0051179;cellular process#GO:0009987;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000003750.3|UniProtKB=G3QME3 G3QME3 TBRG1 PTHR22715:SF0 TRANSFORMING GROWTH FACTOR BETA REGULATED GENE 1 TRANSFORMING GROWTH FACTOR BETA REGULATOR 1 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207;growth factor#PC00112 GORGO|Ensembl=ENSGGOG00000006878.3|UniProtKB=G3S7C1 G3S7C1 TBC1D9 PTHR47666:SF3 PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC TBC1 DOMAIN FAMILY MEMBER 9 GORGO|Ensembl=ENSGGOG00000038830.1|UniProtKB=A0A2I2ZVR9 A0A2I2ZVR9 S100G PTHR11639:SF73 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-G protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 sarcoplasm#GO:0016528;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sarcoplasmic reticulum#GO:0016529;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000005313.3|UniProtKB=G3QRF3 G3QRF3 GRM4 PTHR24060:SF23 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 4 glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 GORGO|Ensembl=ENSGGOG00000009706.3|UniProtKB=G3R2M3 G3R2M3 PTHR24056:SF120 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000042244.1|UniProtKB=A0A2I2Z1G5 A0A2I2Z1G5 NCBP2 PTHR18847:SF6 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;negative regulation of cellular process#GO:0048523;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;macromolecule localization#GO:0033036;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nitrogen compound transport#GO:0071705;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;catabolic process#GO:0009056;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing#GO:0008380;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;mRNA processing#GO:0006397;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004572.3|UniProtKB=G3QPI7 G3QPI7 TNFAIP1 PTHR11145:SF17 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER BTB_POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 2 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;negative regulation of response to stimulus#GO:0048585;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of Rho protein signal transduction#GO:0035023;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014207.3|UniProtKB=G3RE81 G3RE81 MRPL44 PTHR11207:SF5 RIBONUCLEASE III LARGE RIBOSOMAL SUBUNIT PROTEIN ML44 double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;mitochondrial translation#GO:0032543;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translation#GO:0006412;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;primary miRNA processing#GO:0031053;nucleobase-containing compound biosynthetic process#GO:0034654;translational elongation#GO:0006414;metabolic process#GO:0008152;protein biosynthetic process#GO:0160307;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187 organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000025281.2|UniProtKB=G3RV56 G3RV56 RFC2 PTHR11669:SF5 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 2 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular process#GO:0009987;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 replication fork#GO:0005657;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 GORGO|Ensembl=ENSGGOG00000011267.3|UniProtKB=G3R6M6 G3R6M6 POLR2E PTHR10535:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 GORGO|Ensembl=ENSGGOG00000022462.2|UniProtKB=G3RSX3 G3RSX3 BAK1 PTHR11256:SF59 BCL-2 RELATED BCL-2 HOMOLOGOUS ANTAGONIST_KILLER channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 apoptotic signaling pathway#GO:0097190;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;regulation of biological process#GO:0050789 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739 Apoptosis signaling pathway#P00006>Bak#P00275 GORGO|Ensembl=ENSGGOG00000014020.3|UniProtKB=G3RDR4 G3RDR4 DEAF1 PTHR10237:SF15 DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000015817.3|UniProtKB=G3RID3 G3RID3 PTHR24006:SF796 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBL CARBOXYL-TERMINAL HYDROLASE 18 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000005841.3|UniProtKB=G3QSS4 G3QSS4 SELE PTHR19325:SF493 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING E-SELECTIN organic acid binding#GO:0043177;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;carbohydrate binding#GO:0030246;oligosaccharide binding#GO:0070492;carbohydrate derivative binding#GO:0097367 response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;cell motility#GO:0048870;cell migration#GO:0016477;leukocyte cell-cell adhesion#GO:0007159;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;response to peptide#GO:1901652;cell adhesion#GO:0007155;immune system process#GO:0002376;leukocyte migration#GO:0050900 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 complement component#PC00078;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000040190.1|UniProtKB=A0A2I2ZPJ8 A0A2I2ZPJ8 PTHR11815:SF13 SUCCINYL-COA SYNTHETASE BETA CHAIN SUBFAMILY NOT NAMED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;tricarboxylic acid cycle#GO:0006099;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;aerobic respiration#GO:0009060;cellular respiration#GO:0045333 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000009505.3|UniProtKB=G3R251 G3R251 PPARGC1B PTHR15528:SF12 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-BETA transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;multicellular organismal-level homeostasis#GO:0048871;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000012342.3|UniProtKB=A0A2I2ZLK9 A0A2I2ZLK9 IRF4 PTHR11949:SF6 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013052.3|UniProtKB=G3RBA1 G3RBA1 DHX38 PTHR18934:SF91 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16 helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004214.3|UniProtKB=A0A2I2ZJU2 A0A2I2ZJU2 FAAP100 PTHR14890:SF1 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 100 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 100 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013128.4|UniProtKB=G3RBF9 G3RBF9 ADAM17 PTHR45702:SF6 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cell communication#GO:0007154;protein metabolic process#GO:0019538;proteolysis#GO:0006508;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;biological regulation#GO:0065007;membrane protein ectodomain proteolysis#GO:0006509;membrane protein proteolysis#GO:0033619;signal transduction#GO:0007165;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>TACE#P00147;Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-amyloid secretase pathway#P00003>TACE#P00092 GORGO|Ensembl=ENSGGOG00000023556.2|UniProtKB=A0A2I2Y5D4 A0A2I2Y5D4 PTHR12800:SF5 CDC37-RELATED HSP90 CO-CHAPERONE CDC37 heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;protein folding#GO:0006457;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of innate immune response#GO:0045088;macromolecule metabolic process#GO:0043170;regulation of cytokine-mediated signaling pathway#GO:0001959;protein stabilization#GO:0050821;metabolic process#GO:0008152;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of response to external stimulus#GO:0032101;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to cytokine stimulus#GO:0060759;regulation of protein stability#GO:0031647;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;protein folding chaperone complex#GO:0101031 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000017018.3|UniProtKB=G3RLG3 G3RLG3 MRGBP PTHR13581:SF5 MRG-BINDING PROTEIN MRG_MORF4L-BINDING PROTEIN regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011344.4|UniProtKB=G3R6U9 G3R6U9 TENM3 PTHR11219:SF65 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-3 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;neuron development#GO:0048666;axonogenesis#GO:0007409;synaptic membrane adhesion#GO:0099560;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411;system development#GO:0048731;anatomical structure development#GO:0048856;synapse organization#GO:0050808;cell junction organization#GO:0034330 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000002990.3|UniProtKB=G3QKG9 G3QKG9 FNDC3B PTHR13817:SF44 TITIN FIBRONECTIN TYPE III DOMAIN CONTAINING 3B structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000010658.3|UniProtKB=A0A2I2YV78 A0A2I2YV78 MAPKAPK2 PTHR24349:SF63 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 2 calmodulin binding#GO:0005516;transferase activity#GO:0016740;kinase activity#GO:0016301;mitogen-activated protein kinase binding#GO:0051019;protein serine/threonine kinase activity#GO:0004674;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;calcium/calmodulin-dependent protein kinase activity#GO:0004683;enzyme binding#GO:0019899;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;cellular response to growth factor stimulus#GO:0071363;response to peptide#GO:1901652;immune system process#GO:0002376;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;response to endogenous stimulus#GO:0009719;vascular endothelial growth factor receptor signaling pathway#GO:0048010;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of innate immune response#GO:0045088;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of immune response#GO:0050776;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;inflammatory response#GO:0006954;regulation of defense response#GO:0031347;regulation of response to biotic stimulus#GO:0002831;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Angiogenesis#P00005>MAPKAPK2/3#P00244;p38 MAPK pathway#P05918>MAPKAP-K2#P05920;Interleukin signaling pathway#P00036>MAPKAPK2#P00979;Ras Pathway#P04393>MAPKAP#P04564;PDGF signaling pathway#P00047>MAPKAPK2#P01157;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415 GORGO|Ensembl=ENSGGOG00000009390.3|UniProtKB=G3R1V2 G3R1V2 ATAD2 PTHR23069:SF4 AAA DOMAIN-CONTAINING ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2 ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;histone binding#GO:0042393;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657 DNA-templated transcription initiation#GO:0006352;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;transcription initiation at RNA polymerase II promoter#GO:0006367;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex disassembly#GO:0032984;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of biosynthetic process#GO:0009891;biological regulation#GO:0065007;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleosome organization#GO:0034728;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;transcription by RNA polymerase II#GO:0006366 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000025398.2|UniProtKB=A0A2I2Y471 A0A2I2Y471 PTHR23147:SF80 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 4B circadian rhythm#GO:0007623;rhythmic process#GO:0048511 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000013345.3|UniProtKB=G3SB01 G3SB01 PPFIBP1 PTHR12587:SF16 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-BETA-1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;neuromuscular junction development#GO:0007528;cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808 presynapse#GO:0098793;presynaptic active zone#GO:0048786;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000023967.2|UniProtKB=G3RQ64 G3RQ64 EBPL PTHR14207:SF4 STEROL ISOMERASE EMOPAMIL-BINDING PROTEIN-LIKE catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;primary metabolic process#GO:0044238;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000004248.3|UniProtKB=A0A2I2ZTD7 A0A2I2ZTD7 PIK3R1 PTHR10155:SF3 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;response to endogenous stimulus#GO:0009719;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane protein complex#GO:0098796;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 kinase modulator#PC00140 CCKR signaling map#P06959>p85#P07212;T cell activation#P00053>PI3K#P01322;p53 pathway feedback loops 2#P04398>PI3K#P04661;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413;Gonadotropin-releasing hormone receptor pathway#P06664>PI3K#P06766;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;PI3 kinase pathway#P00048>p85#P01202;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168 GORGO|Ensembl=ENSGGOG00000008867.3|UniProtKB=G3R0I2 G3R0I2 CDC23 PTHR12558:SF10 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 23 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 regulation of nuclear division#GO:0051783;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;cell division#GO:0051301;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell cycle phase transition#GO:1901987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome segregation#GO:0051983;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;positive regulation of cellular component organization#GO:0051130;protein modification by small protein conjugation or removal#GO:0070647 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000003472.3|UniProtKB=G3QLQ6 G3QLQ6 ATG16L2 PTHR19878:SF7 AUTOPHAGY PROTEIN 16-LIKE PROTEIN ATG16L2 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;metabolic process#GO:0008152;organelle assembly#GO:0070925;catabolic process#GO:0009056;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914 cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;autophagosome#GO:0005776 GORGO|Ensembl=ENSGGOG00000015636.3|UniProtKB=G3SAM4 G3SAM4 PAX3 PTHR45636:SF17 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000003043.3|UniProtKB=G3QKL6 G3QKL6 NFE2 PTHR24411:SF26 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR TRANSCRIPTION FACTOR NF-E2 45 KDA SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000041335.1|UniProtKB=G3RHP6 G3RHP6 LOC101130426 PTHR10751:SF113 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 heterotrimeric G-protein#PC00117;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000000232.3|UniProtKB=G3QDB8 G3QDB8 GCSH PTHR11715:SF42 GLYCINE CLEAVAGE SYSTEM H PROTEIN GLYCINE CLEAVAGE SYSTEM H PROTEIN, MITOCHONDRIAL primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000013931.3|UniProtKB=G3RTM0 G3RTM0 LHX4 PTHR24208:SF116 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX4 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000005828.3|UniProtKB=G3QSR7 G3QSR7 CCDC136 PTHR15715:SF26 CENTROSOMAL PROTEIN OF 170 KDA COILED-COIL DOMAIN-CONTAINING PROTEIN 136 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;fertilization#GO:0009566;regulation of hippo signaling#GO:0035330;gamete generation#GO:0007276;cell differentiation#GO:0030154;regulation of signaling#GO:0023051;acrosome assembly#GO:0001675;regulation of intracellular signal transduction#GO:1902531;spermatid differentiation#GO:0048515;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;cellular process#GO:0009987;single fertilization#GO:0007338;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of signal transduction#GO:0009968;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;vesicle organization#GO:0016050;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;spermatid development#GO:0007286;sexual reproduction#GO:0019953;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;male gamete generation#GO:0048232;regulation of response to stimulus#GO:0048583;spermatogenesis#GO:0007283;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869 vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;acrosomal membrane#GO:0002080;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027988.2|UniProtKB=G3S8N0 G3S8N0 PTHR23187:SF2 FLJ44216 PROTEIN-RELATED SKI_DACH DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000006118.3|UniProtKB=A0A2I2YIM6 A0A2I2YIM6 ITGB1 PTHR10082:SF28 INTEGRIN BETA SUBUNIT INTEGRIN BETA-1 cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;integrin binding#GO:0005178;cytokine binding#GO:0019955;laminin binding#GO:0043236;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;binding#GO:0005488;collagen binding#GO:0005518;protein-containing complex binding#GO:0044877;extracellular matrix binding#GO:0050840;protein binding#GO:0005515 cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell adhesion mediated by integrin#GO:0033627;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;cell migration#GO:0016477 signaling receptor complex#GO:0043235;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;integrin complex#GO:0008305;anchoring junction#GO:0070161;membrane protein complex#GO:0098796;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;synapse#GO:0045202;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 integrin#PC00126 CCKR signaling map#P06959>ITGB1#P07113;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin beta#P00931;CCKR signaling map#P06959>ITGB1#G06984;CCKR signaling map#P06959>ITGB1#G07277;Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820 GORGO|Ensembl=ENSGGOG00000004932.3|UniProtKB=G3QQG6 G3QQG6 LOC101150409 PTHR46060:SF2 MARINER MOS1 TRANSPOSASE-LIKE PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR catalytic activity, acting on a protein#GO:0140096;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;DNA binding#GO:0003677;histone H3 methyltransferase activity#GO:0140938;double-stranded DNA binding#GO:0003690;histone H3K4 methyltransferase activity#GO:0042800;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;nucleic acid binding#GO:0003676;N-methyltransferase activity#GO:0008170;catalytic activity, acting on DNA#GO:0140097;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;histone H3K36 methyltransferase activity#GO:0046975;protein binding#GO:0005515;DNA endonuclease activity#GO:0004520;histone modifying activity#GO:0140993;nuclease activity#GO:0004518;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;binding#GO:0005488;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;single-stranded DNA binding#GO:0003697;enzyme binding#GO:0019899 negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;double-strand break repair via nonhomologous end joining#GO:0006303;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;DNA integrity checkpoint signaling#GO:0031570;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726 site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000024655.2|UniProtKB=G3RWN6 G3RWN6 PPCDC PTHR14359:SF6 HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;ribonucleotide binding#GO:0032553;lyase activity#GO:0016829;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Coenzyme A biosynthesis#P02736>Pantothenoylcysteine decarboxylase#P02883;Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882 GORGO|Ensembl=ENSGGOG00000025038.2|UniProtKB=G3RRL1 G3RRL1 RCN1 PTHR10827:SF17 RETICULOCALBIN RETICULOCALBIN-1 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000017125.3|UniProtKB=G3S5C1 G3S5C1 CMTM5 PTHR22776:SF26 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 5 immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response#GO:0006955;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008900.3|UniProtKB=G3RXV6 G3RXV6 LOC101135346 PTHR11481:SF101 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000001362.3|UniProtKB=A0A2I2YLJ8 A0A2I2YLJ8 VLDLR PTHR24270:SF16 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED VERY LOW-DENSITY LIPOPROTEIN RECEPTOR protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;developmental process#GO:0032502;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;multicellular organism development#GO:0007275;import into cell#GO:0098657;establishment of localization#GO:0051234;central nervous system development#GO:0007417;endocytosis#GO:0006897;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;localization#GO:0051179;anatomical structure development#GO:0048856 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000000750.3|UniProtKB=G3QEP0 G3QEP0 ADAM12 PTHR11905:SF112 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 12 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000000981.3|UniProtKB=A0A2I2Y9L3 A0A2I2Y9L3 HSPA12A PTHR14187:SF46 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12A GORGO|Ensembl=ENSGGOG00000005246.3|UniProtKB=A0A2I2Z3R7 A0A2I2Z3R7 NCAM2 PTHR10075:SF120 BASIGIN RELATED NEURAL CELL ADHESION MOLECULE 1 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000011926.3|UniProtKB=G3R8D2 G3R8D2 CWC15 PTHR12718:SF2 CELL CYCLE CONTROL PROTEIN CWF15 SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000014726.3|UniProtKB=G3RFK5 G3RFK5 PHTF1 PTHR12680:SF8 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF PROTEIN PHTF1 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000038446.1|UniProtKB=A0A2I2ZTY6 A0A2I2ZTY6 PTHR35819:SF3 PICALM INTERACTING MITOTIC REGULATOR PIMREG PICALM INTERACTING MITOTIC REGULATOR GORGO|Ensembl=ENSGGOG00000010093.3|UniProtKB=G3R3M0 G3R3M0 PAWR PTHR15093:SF1 PROSTATE APOPTOSIS RESPONSE PROTEIN PAR-4 PRKC APOPTOSIS WT1 REGULATOR PROTEIN programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;cell communication#GO:0007154;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;biological regulation#GO:0065007;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;apoptotic signaling pathway#GO:0097190;positive regulation of apoptotic process#GO:0043065 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011455.3|UniProtKB=G3R742 G3R742 ZNF483 PTHR23226:SF412 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022729.2|UniProtKB=A0A2I2ZH17 A0A2I2ZH17 CAMK2D PTHR24347:SF365 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT DELTA calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096 regulation of protein localization to membrane#GO:1905475;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of synaptic plasticity#GO:0048167;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of neuronal synaptic plasticity#GO:0048168 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;postsynaptic density#GO:0014069;axon#GO:0030424;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;neuron projection#GO:0043005;postsynapse#GO:0098794 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 GORGO|Ensembl=ENSGGOG00000015047.3|UniProtKB=G3RGD8 G3RGD8 PUS3 PTHR11142:SF5 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE(38_39) SYNTHASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA modification#GO:0016556;pseudouridine synthesis#GO:0001522;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 lyase#PC00144 GORGO|Ensembl=ENSGGOG00000040763.1|UniProtKB=A0A2I2ZJN2 A0A2I2ZJN2 PTHR19433:SF111 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 4 response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to other organism#GO:0051707;response to stimulus#GO:0050896;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000003387.3|UniProtKB=A0A2I2ZM94 A0A2I2ZM94 LAIR2 PTHR11738:SF129 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888 regulation of immune response#GO:0050776;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000002285.3|UniProtKB=G3QIN8 G3QIN8 C5 PTHR11412:SF83 MACROGLOBULIN / COMPLEMENT COMPLEMENT C5 molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 defense response to other organism#GO:0098542;response to chemical#GO:0042221;taxis#GO:0042330;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;humoral immune response#GO:0006959;immune effector process#GO:0002252;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;complement activation#GO:0006956;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;regulation of immune response#GO:0050776;chemotaxis#GO:0006935 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000016044.3|UniProtKB=G3RIY0 G3RIY0 WFDC13 PTHR19441:SF22 WAP four-disulfide core domain protein WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 13 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000011972.3|UniProtKB=G3R8G8 G3R8G8 TMEM219 PTHR16002:SF6 TRANSMEMBRANE PROTEIN 248-LIKE INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3 RECEPTOR GORGO|Ensembl=ENSGGOG00000042035.1|UniProtKB=G3SKW4 G3SKW4 LOC101143363 PTHR48001:SF79 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7C2 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006690.3|UniProtKB=A0A2I2ZME3 A0A2I2ZME3 FAM76A PTHR46176:SF2 LD21662P PROTEIN FAM76A intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nuclear speck#GO:0016607;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604 GORGO|Ensembl=ENSGGOG00000010578.3|UniProtKB=G3R4V1 G3R4V1 EXOSC2 PTHR21321:SF4 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP4 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;snRNA 3'-end processing#GO:0034472;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound catabolic process#GO:0034655;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;snRNA processing#GO:0016180;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000005331.3|UniProtKB=G3SE31 G3SE31 BSND PTHR28399:SF1 BARTTIN BARTTIN ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 transport#GO:0006810;chloride transport#GO:0006821;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000013480.3|UniProtKB=G3RCC4 G3RCC4 CD300LB PTHR11860:SF103 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 7 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 immune system process#GO:0002376;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000003262.2|UniProtKB=G3QL62 G3QL62 SMIM10L3 PTHR31980:SF3 PROTEIN FAM220A PROTEIN FAM220A intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010043.3|UniProtKB=G3R3H0 G3R3H0 C1QC PTHR15427:SF29 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT C signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 immune system process#GO:0002376;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;adaptive immune response#GO:0002250 extracellular protein-containing complex#GO:0140392;synaptic membrane#GO:0097060;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;glutamatergic synapse#GO:0098978;extracellular region#GO:0005576;synapse#GO:0045202;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013814.3|UniProtKB=G3RN19 G3RN19 SEPTIN4 PTHR18884:SF71 SEPTIN SEPTIN-4 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;cytokinesis#GO:0000910;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cell cycle process#GO:0022402;cell division#GO:0051301;regulation of transport#GO:0051049;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987 cell periphery#GO:0071944;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;presynapse#GO:0098793;secretory vesicle#GO:0099503;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cell junction#GO:0030054;cell cortex#GO:0005938;intracellular vesicle#GO:0097708;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 GORGO|Ensembl=ENSGGOG00000003902.3|UniProtKB=G3QMU0 G3QMU0 ESYT3 PTHR45761:SF4 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-3 phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylcholine binding#GO:0031210;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;cation binding#GO:0043169;lipid binding#GO:0008289;metal ion binding#GO:0046872 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000003533.3|UniProtKB=G3QLX3 G3QLX3 TPR PTHR18898:SF8 NUCLEOPROTEIN TPR-RELATED NUCLEOPROTEIN TPR structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 metabolic process#GO:0008152;regulation of mitotic spindle assembly#GO:1901673;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;regulation of mitotic spindle organization#GO:0060236;regulation of spindle assembly#GO:0090169;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of microtubule-based process#GO:0032886;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000016194.3|UniProtKB=A0A2I2YWQ5 A0A2I2YWQ5 PTHR33505:SF6 ZGC:162634 PROTEIN PREY, MITOCHONDRIAL GORGO|Ensembl=ENSGGOG00000008372.3|UniProtKB=A0A2I2ZYH9 A0A2I2ZYH9 PDE1B PTHR11347:SF194 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1B hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell body#GO:0044297 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000011271.3|UniProtKB=G3RSB6 G3RSB6 TMEM59L PTHR28652:SF1 TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN TRANSMEMBRANE PROTEIN 59-LIKE GORGO|Ensembl=ENSGGOG00000005084.3|UniProtKB=G3QQV8 G3QQV8 HTR3B PTHR18945:SF53 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3B molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215 cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;transport#GO:0006810;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422 GORGO|Ensembl=ENSGGOG00000017093.3|UniProtKB=A0A2I2ZL60 A0A2I2ZL60 MARK2 PTHR24346:SF56 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE MARK2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000013429.3|UniProtKB=G3RC74 G3RC74 PTHR14409:SF1 MANNOSIDASE, BETA A, LYSOSOMAL-LIKE, MANBAL PROTEIN MANNOSIDASE BETA LIKE GORGO|Ensembl=ENSGGOG00000016598.3|UniProtKB=A0A2I2ZG24 A0A2I2ZG24 GAD1 PTHR45677:SF5 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 1 lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;presynaptic active zone#GO:0048786;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;presynapse#GO:0098793 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 GORGO|Ensembl=ENSGGOG00000013498.3|UniProtKB=G3RCE0 G3RCE0 TGM2 PTHR11590:SF6 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000015735.3|UniProtKB=G3RI60 G3RI60 LOC101141171 PTHR12629:SF35 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 3-BETA hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;nucleotide catabolic process#GO:0009166;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000026072.2|UniProtKB=G3SAI5 G3SAI5 HTATSF1 PTHR15608:SF0 SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2 17S U2 SNRNP COMPLEX COMPONENT HTATSF1 binding#GO:0005488;nucleic acid binding#GO:0003676;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463;RNA binding#GO:0003723 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA splicing, via transesterification reactions#GO:0000375;localization#GO:0051179;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;protein localization to organelle#GO:0033365 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;site of double-strand break#GO:0035861;small nuclear ribonucleoprotein complex#GO:0030532;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000016932.3|UniProtKB=G3RPM0 G3RPM0 GPI PTHR11469:SF1 GLUCOSE-6-PHOSPHATE ISOMERASE GLUCOSE-6-PHOSPHATE ISOMERASE binding#GO:0005488;small molecule binding#GO:0036094;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;monosaccharide binding#GO:0048029;carbohydrate binding#GO:0030246;intramolecular oxidoreductase activity#GO:0016860 purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine ribonucleotide catabolic process#GO:0009154;hexose biosynthetic process#GO:0019319;nucleoside diphosphate catabolic process#GO:0009134;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;glucose 6-phosphate metabolic process#GO:0051156;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Glucose-P-Isomerase#P03080;Glycolysis#P00024>Phosphoglucose isomerase#P00674 GORGO|Ensembl=ENSGGOG00000013847.3|UniProtKB=G3SCT1 G3SCT1 GIP PTHR15211:SF0 GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE GASTRIC INHIBITORY POLYPEPTIDE G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 response to starvation#GO:0042594;response to nutrient levels#GO:0031667;response to stress#GO:0006950;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014172.3|UniProtKB=G3SCE8 G3SCE8 RNPEP PTHR45726:SF1 LEUKOTRIENE A-4 HYDROLASE AMINOPEPTIDASE B hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015490.3|UniProtKB=G3RHJ2 G3RHJ2 ANKRD11 PTHR24145:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 11 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 11 anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502 GORGO|Ensembl=ENSGGOG00000015239.3|UniProtKB=G3RGW2 G3RGW2 CACNB3 PTHR11824:SF8 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-3 voltage-gated ion channel#PC00241 5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587 GORGO|Ensembl=ENSGGOG00000006998.3|UniProtKB=G3QVR6 G3QVR6 ADAMTS5 PTHR13723:SF37 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 5 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000023947.2|UniProtKB=A0A2I2ZPR9 A0A2I2ZPR9 ARMT1 PTHR12260:SF6 DAMAGE-CONTROL PHOSPHATASE ARMT1 DAMAGE-CONTROL PHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to stimulus#GO:0050896 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000013572.3|UniProtKB=G3RCK3 G3RCK3 GNMT PTHR16458:SF2 GLYCINE N-METHYLTRANSFERASE GLYCINE N-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000013681.3|UniProtKB=G3RCW1 G3RCW1 SLC25A25 PTHR24089:SF762 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SLC25A25 phosphate transmembrane transporter activity#GO:0005315;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;purine nucleotide transmembrane transporter activity#GO:0015216;active transmembrane transporter activity#GO:0022804 nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;localization#GO:0051179;establishment of localization#GO:0051234 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 GORGO|Ensembl=ENSGGOG00000006305.3|UniProtKB=G3SAR9 G3SAR9 PTPRU PTHR19134:SF207 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE U phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;cell communication#GO:0007154;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001379.3|UniProtKB=A0A2I2ZIL5 A0A2I2ZIL5 MYB PTHR45614:SF5 MYB PROTEIN-RELATED TRANSCRIPTIONAL ACTIVATOR MYB sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell cycle#GO:0007049 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000006616.3|UniProtKB=G3QUR3 G3QUR3 GPX2 PTHR11592:SF36 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 2 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000006306.3|UniProtKB=G3S595 G3S595 HSD17B14 PTHR43658:SF16 SHORT-CHAIN DEHYDROGENASE/REDUCTASE L-FUCOSE DEHYDROGENASE intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009225.3|UniProtKB=G3R1F3 G3R1F3 SLCO5A1 PTHR11388:SF142 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 5A1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011477.3|UniProtKB=G3SBB5 G3SBB5 MTFR1L PTHR14215:SF3 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 1-LIKE organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;organelle fission#GO:0048285;aerobic respiration#GO:0009060 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000008445.3|UniProtKB=G3QZF0 G3QZF0 OSBPL2 PTHR10972:SF153 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 2 binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934;alcohol binding#GO:0043178;lipid binding#GO:0008289;cholesterol binding#GO:0015485;steroid binding#GO:0005496 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000008274.3|UniProtKB=A0A2I2ZU07 A0A2I2ZU07 NT5C1A PTHR31367:SF2 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1A phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253 nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside metabolic process#GO:0042278;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;adenosine metabolic process#GO:0046085;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000014678.3|UniProtKB=G3RFF2 G3RFF2 TFF3 PTHR13826:SF16 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 3 system process#GO:0003008;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;epithelial structure maintenance#GO:0010669;homeostatic process#GO:0042592;digestion#GO:0007586;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000008071.3|UniProtKB=G3SFQ4 G3SFQ4 CAPN5 PTHR10183:SF402 CALPAIN CALPAIN-5 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000001303.3|UniProtKB=G3QG36 G3QG36 ARSG PTHR42693:SF42 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE G hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000008778.3|UniProtKB=A0A2I2YAF7 A0A2I2YAF7 AKAP7 PTHR15934:SF6 RNA 2',3'-CYCLIC PHOSPHODIESTERASE A-KINASE ANCHOR PROTEIN 7 ISOFORM GAMMA protein kinase A binding#GO:0051018;binding#GO:0005488;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000012560.3|UniProtKB=A0A2I2ZDT0 A0A2I2ZDT0 MAEL PTHR21358:SF4 PROTEIN MAELSTROM HOMOLOG PROTEIN MAELSTROM HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nucleobase-containing compound biosynthetic process#GO:0034654;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;male meiotic nuclear division#GO:0007140;nuclear division#GO:0000280;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;gamete generation#GO:0007276;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;spermatogenesis#GO:0007283;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;regulation of DNA-templated transcription#GO:0006355;organelle fission#GO:0048285;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001172.3|UniProtKB=G3QFS5 G3QFS5 CDK17 PTHR24056:SF128 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 17 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010614.3|UniProtKB=G3R4Y1 G3R4Y1 GPR20 PTHR24232:SF7 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 20 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000034973.2|UniProtKB=G3SKH8 G3SKH8 ZCCHC7 PTHR46543:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;tRNA metabolic process#GO:0006399;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;snRNA metabolic process#GO:0016073;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000041703.1|UniProtKB=A0A2I2YK35 A0A2I2YK35 TSPAN9 PTHR19282:SF41 TETRASPANIN TETRASPANIN-9 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002413.3|UniProtKB=G3QJ00 G3QJ00 SORBS3 PTHR14167:SF54 SH3 DOMAIN-CONTAINING VINEXIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytoskeleton organization#GO:0007010;cell-substrate adhesion#GO:0031589;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell adhesion#GO:0007155;cellular component organization#GO:0016043;organelle organization#GO:0006996 cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011977.4|UniProtKB=A0A2I2ZGI7 A0A2I2ZGI7 ITIH2 PTHR10338:SF14 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H2 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000013154.3|UniProtKB=G3RBH8 G3RBH8 SPPL2A PTHR12174:SF34 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2A catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 lysosomal membrane#GO:0005765;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;cytoplasm#GO:0005737;vacuole#GO:0005773;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum#GO:0005783;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;Golgi-associated vesicle membrane#GO:0030660;intracellular organelle#GO:0043229;side of membrane#GO:0098552;organelle subcompartment#GO:0031984;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;endoplasmic reticulum membrane#GO:0005789;Golgi-associated vesicle#GO:0005798;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;aspartic protease#PC00053 GORGO|Ensembl=ENSGGOG00000015336.3|UniProtKB=G3RH49 G3RH49 GRM3 PTHR24060:SF160 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 3 glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Ionotropic glutamate receptor pathway#P00037>mGluR 2/3#P01014;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Metabotropic glutamate receptor group II pathway#P00040>mGluR2/3#P01048 GORGO|Ensembl=ENSGGOG00000006440.3|UniProtKB=G3SD21 G3SD21 SLC26A7 PTHR11814:SF75 SULFATE TRANSPORTER ANION EXCHANGE TRANSPORTER carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;dicarboxylic acid transport#GO:0006835;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chloride transmembrane transport#GO:1902476 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000005677.3|UniProtKB=G3QSC4 G3QSC4 SCP2D1 PTHR10094:SF25 STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN SCP2 STEROL-BINDING DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000004424.3|UniProtKB=A0A2I2YZZ9 A0A2I2YZZ9 POLD2 PTHR10416:SF0 DNA POLYMERASE DELTA SUBUNIT 2 DNA POLYMERASE DELTA SUBUNIT 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated DNA replication#GO:0006261;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;replisome#GO:0030894;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 GORGO|Ensembl=ENSGGOG00000004117.3|UniProtKB=G3QND3 G3QND3 GOLGA1 PTHR23157:SF24 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GOLGIN SUBFAMILY A MEMBER 1 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011725.3|UniProtKB=G3S434 G3S434 DUOXA1 PTHR31158:SF3 DUAL OXIDASE 2 DUAL OXIDASE MATURATION FACTOR 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000027310.2|UniProtKB=G3RLX2 G3RLX2 MAP2 PTHR11501:SF15 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 2 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of microtubule-based process#GO:0032886;neuron development#GO:0048666;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;regulation of microtubule-based movement#GO:0060632;cell differentiation#GO:0030154 axon#GO:0030424;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell body#GO:0044297;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000039180.1|UniProtKB=A0A2I2YV84 A0A2I2YV84 LOC101138952 PTHR24404:SF134 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 350 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000001281.3|UniProtKB=G3RUV2 G3RUV2 PLPPR1 PTHR10165:SF41 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 dephosphorylation#GO:0016311;cell communication#GO:0007154;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000025720.2|UniProtKB=G3RMT2 G3RMT2 CNTLN PTHR18957:SF0 CENTLEIN CENTLEIN cytoskeleton organization#GO:0007010;cell cycle process#GO:0022402;cellular process#GO:0009987;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000023573.2|UniProtKB=G3RZ54 G3RZ54 LOC101130387 PTHR12035:SF96 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 16 carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;organic acid binding#GO:0043177 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000015790.3|UniProtKB=G3RIB4 G3RIB4 TTF2 PTHR45626:SF50 TRANSCRIPTION TERMINATION FACTOR 2-RELATED TRANSCRIPTION TERMINATION FACTOR 2 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity#GO:0140657 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 GORGO|Ensembl=ENSGGOG00000028443.2|UniProtKB=G3SBV0 G3SBV0 PTHR15959:SF2 SYNTAXIN-18 SYNTAXIN-18 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796 membrane traffic protein#PC00150;SNARE protein#PC00034 GORGO|Ensembl=ENSGGOG00000005640.3|UniProtKB=G3QSA2 G3QSA2 CMTR1 PTHR16121:SF0 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000022600.2|UniProtKB=G3RS17 G3RS17 PTHR23267:SF216 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-V REGION HP 123E6-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000015564.3|UniProtKB=A0A2I2YQR2 A0A2I2YQR2 KCNN2 PTHR10153:SF43 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 2 protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;calmodulin binding#GO:0005516;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;calcium-activated potassium channel activity#GO:0015269;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805 cell junction#GO:0030054;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;dendrite#GO:0030425;dendritic tree#GO:0097447;postsynapse#GO:0098794;cell body#GO:0044297;dendritic spine#GO:0043197;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000015089.3|UniProtKB=A0A2I2YJ37 A0A2I2YJ37 PTHR12056:SF4 DNA-DIRECTED RNA POLYMERASES I, II, AND III DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on RNA#GO:0140098 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 GORGO|Ensembl=ENSGGOG00000012671.3|UniProtKB=G3RAA2 G3RAA2 PPP3CC PTHR45673:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT GAMMA ISOFORM binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;calcineurin-mediated signaling#GO:0097720;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 B cell activation#P00010>Calcineurin#P00386;Wnt signaling pathway#P00057>Calcineurin#P01446;T cell activation#P00053>Calcineurin#P01315 GORGO|Ensembl=ENSGGOG00000023785.2|UniProtKB=A0A2I2Y5H0 A0A2I2Y5H0 PTHR10257:SF123 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM enzyme activator activity#GO:0008047;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 GORGO|Ensembl=ENSGGOG00000003090.3|UniProtKB=G3QKQ7 G3QKQ7 HPF1 PTHR13386:SF2 HISTONE PARYLATION FACTOR 1 HISTONE PARYLATION FACTOR 1 carbohydrate derivative binding#GO:0097367;binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;chromatin remodeling#GO:0006338;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000015883.3|UniProtKB=A0A2K5TIZ8 A0A2K5TIZ8 NDUFB9 PTHR12868:SF1 NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9 respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006484.3|UniProtKB=G3QUD7 G3QUD7 TRMT10C PTHR13563:SF5 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG C nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;mitochondrion#GO:0005739;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001388.3|UniProtKB=A1YER0 A1YER0 SIX1 PTHR10390:SF13 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000024772.2|UniProtKB=G3SCM3 G3SCM3 PTHR11524:SF13 60S RIBOSOMAL PROTEIN L7 RIBOSOMAL PROTEIN UL30-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001007.3|UniProtKB=G3QFC4 G3QFC4 SNAP29 PTHR19305:SF42 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 29 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905 secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;vesicle fusion#GO:0006906;export from cell#GO:0140352;cellular component organization#GO:0016043;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987 SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049 GORGO|Ensembl=ENSGGOG00000037230.1|UniProtKB=A0A2I2ZDJ4 A0A2I2ZDJ4 TMT1A PTHR45036:SF5 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE LIKE 7A1-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000015345.3|UniProtKB=G3RH52 G3RH52 ACTRT1 PTHR11937:SF153 ACTIN ACTIN-RELATED PROTEIN T1 chromatin binding#GO:0003682;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;structural molecule activity#GO:0005198 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;actin cytoskeleton#GO:0015629;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000003720.3|UniProtKB=G3QMC3 G3QMC3 BMPR1A PTHR23255:SF50 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1A protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;regionalization#GO:0003002;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;dorsal/ventral pattern formation#GO:0009953;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 serine/threonine protein kinase receptor#PC00205 Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442 GORGO|Ensembl=ENSGGOG00000013835.3|UniProtKB=G3RDA5 G3RDA5 PEAR1 PTHR24052:SF12 DELTA-RELATED PLATELET ENDOTHELIAL AGGREGATION RECEPTOR 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000011509.3|UniProtKB=G3R792 G3R792 CA4 PTHR18952:SF95 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 4 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;apical part of cell#GO:0045177;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007005.3|UniProtKB=G3QVS1 G3QVS1 FBXL3 PTHR16134:SF5 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to light stimulus#GO:0009416;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;photoperiodism#GO:0009648;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to external stimulus#GO:0009605;response to radiation#GO:0009314;cellular process#GO:0009987;regulation of circadian rhythm#GO:0042752;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000034977.2|UniProtKB=G3SKJ6 G3SKJ6 IGSF11 PTHR44699:SF1 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000021954.2|UniProtKB=A0A2I2YBX7 A0A2I2YBX7 PTHR23239:SF360 INTERMEDIATE FILAMENT IF ROD DOMAIN-CONTAINING PROTEIN cellular component organization or biogenesis#GO:0071840;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;intermediate filament-based process#GO:0045103;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000004100.3|UniProtKB=G3RY25 G3RY25 OLFML2A PTHR23192:SF29 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 2A signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000014612.3|UniProtKB=G3RF97 G3RF97 PTHR16046:SF11 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR 2 PROTEIN FAM178B GORGO|Ensembl=ENSGGOG00000043704.1|UniProtKB=A0A2I2ZYG6 A0A2I2ZYG6 MEIKIN PTHR38006:SF1 MEIOSIS-SPECIFIC KINETOCHORE PROTEIN MEIOSIS-SPECIFIC KINETOCHORE PROTEIN sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;multicellular organismal reproductive process#GO:0048609;sister chromatid cohesion#GO:0007062;organelle fission#GO:0048285;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;reproductive process#GO:0022414;gamete generation#GO:0007276;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;meiotic sister chromatid cohesion#GO:0051177;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;cellular process#GO:0009987;organelle organization#GO:0006996;male meiotic nuclear division#GO:0007140;male gamete generation#GO:0048232 GORGO|Ensembl=ENSGGOG00000002678.3|UniProtKB=G3QJP2 G3QJP2 PTHR12223:SF31 VESICULAR MANNOSE-BINDING LECTIN PROTEIN ERGIC-53-LIKE binding#GO:0005488;small molecule binding#GO:0036094;carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000007379.3|UniProtKB=G3QWQ7 G3QWQ7 PITPNA PTHR10658:SF28 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN ALPHA ISOFORM phosphatidylcholine binding#GO:0031210;phosphatidylinositol transfer activity#GO:0008526;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;intramembrane lipid carrier activity#GO:0140303;cation binding#GO:0043169;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylcholine intramembrane carrier activity#GO:0008525;lipid carrier activity#GO:0005319;ion binding#GO:0043167;transporter activity#GO:0005215;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;binding#GO:0005488;molecular carrier activity#GO:0140104 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000009823.3|UniProtKB=G3R2Y5 G3R2Y5 RXRB PTHR24083:SF90 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-BETA transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;hormone-mediated signaling pathway#GO:0009755 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000015230.3|UniProtKB=G3RGV1 G3RGV1 LARP4 PTHR22792:SF48 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 4 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000002623.3|UniProtKB=G3QJI7 G3QJI7 TPI1 PTHR21139:SF24 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 ATP metabolic process#GO:0046034;aldehyde metabolic process#GO:0006081;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;ribonucleoside diphosphate metabolic process#GO:0009185;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;glyceraldehyde-3-phosphate metabolic process#GO:0019682;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;hexose biosynthetic process#GO:0019319;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Glycolysis#P00024>Triosephosphate isomerase#P00673 GORGO|Ensembl=ENSGGOG00000016461.3|UniProtKB=G3RK11 G3RK11 HDAC7 PTHR10625:SF42 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 7 catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513 CCKR signaling map#P06959>HDAC7#P07235 GORGO|Ensembl=ENSGGOG00000009264.3|UniProtKB=A0A2I2Z3A2 A0A2I2Z3A2 SF3B1 PTHR12097:SF0 SPLICING FACTOR 3B, SUBUNIT 1-RELATED SPLICING FACTOR 3B SUBUNIT 1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187 U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000006538.3|UniProtKB=A0A2I2YHT0 A0A2I2YHT0 PSMA2 PTHR11599:SF16 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-2 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;peptidase complex#GO:1905368;proteasome complex#GO:0000502;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000007135.3|UniProtKB=G3QW32 G3QW32 DUSP1 PTHR10159:SF309 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 1 catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 negative regulation of signal transduction#GO:0009968;endoderm formation#GO:0001706;embryo development#GO:0009790;signal transduction#GO:0007165;cellular process#GO:0009987;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;endoderm development#GO:0007492;regulation of MAPK cascade#GO:0043408;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;gastrulation#GO:0007369;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;formation of primary germ layer#GO:0001704;regulation of signaling#GO:0023051;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131;Gonadotropin-releasing hormone receptor pathway#P06664>DUSP1#P06823;p38 MAPK pathway#P05918>MKP1#P05922 GORGO|Ensembl=ENSGGOG00000039472.1|UniProtKB=A0A2I2YY84 A0A2I2YY84 PTHR26453:SF135 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006980.3|UniProtKB=A0A2I2Z6B4 A0A2I2Z6B4 CKAP5 PTHR12609:SF0 MICROTUBULE ASSOCIATED PROTEIN XMAP215 CYTOSKELETON-ASSOCIATED PROTEIN 5 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 mitotic cell cycle process#GO:1903047;microtubule organizing center organization#GO:0031023;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;protein-containing complex organization#GO:0043933;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;establishment or maintenance of cell polarity#GO:0007163;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;centrosome cycle#GO:0007098;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043 kinetochore#GO:0000776;microtubule end#GO:1990752;spindle pole#GO:0000922;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000015799.3|UniProtKB=G3RIC2 G3RIC2 AAAS PTHR14494:SF0 ALADIN/ADRACALIN/AAAS ALADIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 chromosome segregation#GO:0007059;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule bundle formation#GO:0001578;nuclear division#GO:0000280;organelle assembly#GO:0070925;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000044199.1|UniProtKB=A0A2I2YA51 A0A2I2YA51 PTHR26453:SF646 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014701.3|UniProtKB=G3RSN6 G3RSN6 CDKN1A PTHR46778:SF1 CYCLIN-DEPENDENT KINASE INHIBITOR 1-RELATED CYCLIN-DEPENDENT KINASE INHIBITOR 1 molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857 regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;response to stress#GO:0006950;DNA damage response#GO:0006974;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase inhibitor#PC00139 Interleukin signaling pathway#P00036>p21CIP1#P00993;p53 pathway feedback loops 2#P04398>P21#G04712;p53 pathway#P00059>P21#P04631;p53 pathway#P00059>p21#G01580;p53 pathway feedback loops 2#P04398>p21#P04667 GORGO|Ensembl=ENSGGOG00000023174.2|UniProtKB=G3RZW6 G3RZW6 ZBBX PTHR28634:SF1 ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1 ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000002073.3|UniProtKB=G3QI40 G3QI40 UPB1 PTHR43674:SF17 NITRILASE C965.09-RELATED BETA-UREIDOPROPIONASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 Pyrimidine Metabolism#P02771>Beta-Ureidopropionase#P03127 GORGO|Ensembl=ENSGGOG00000009687.3|UniProtKB=G3RYZ9 G3RYZ9 ZC4H2 PTHR31058:SF2 ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN multicellular organism development#GO:0007275;positive regulation of cell differentiation#GO:0045597;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of neuron differentiation#GO:0045664;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000010485.3|UniProtKB=G3R4L5 G3R4L5 MAS1 PTHR11334:SF61 MAS-RELATED G-PROTEIN COUPLED RECEPTOR PROTO-ONCOGENE MAS transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040729.1|UniProtKB=A0A2I2ZF22 A0A2I2ZF22 PTHR10562:SF75 SMALL UBIQUITIN-RELATED MODIFIER RAD60_SUMO-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000004445.3|UniProtKB=A0A2I2ZGT4 A0A2I2ZGT4 IFNLR1 PTHR20859:SF55 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON LAMBDA RECEPTOR 1 cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000120.3|UniProtKB=G3QD16 G3QD16 GATA5 PTHR10071:SF289 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell fate commitment#GO:0045165;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;striated muscle tissue development#GO:0014706;positive regulation of transcription by RNA polymerase II#GO:0045944;heart development#GO:0007507;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016654.3|UniProtKB=A0A2I2YQQ8 A0A2I2YQQ8 ZFP30 PTHR24381:SF480 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 59 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000002458.3|UniProtKB=G3QJ39 G3QJ39 PLEKHA6 PTHR12752:SF5 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 6 GORGO|Ensembl=ENSGGOG00000003306.3|UniProtKB=G3QLA1 G3QLA1 FDXR PTHR11938:SF151 FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE NADPH:ADRENODOXIN OXIDOREDUCTASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;steroid biosynthetic process#GO:0006694 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Vitamin D metabolism and pathway#P04396>FdxR#P04604 GORGO|Ensembl=ENSGGOG00000015269.3|UniProtKB=G3RGY8 G3RGY8 TDRD7 PTHR22948:SF14 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008349.3|UniProtKB=A0A2I2YF33 A0A2I2YF33 MBNL2 PTHR12675:SF4 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000008234.3|UniProtKB=G3SAG1 G3SAG1 SOCS5 PTHR10155:SF15 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 5 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 GORGO|Ensembl=ENSGGOG00000014834.3|UniProtKB=G3RFU4 G3RFU4 MSMB PTHR10500:SF8 BETA-MICROSEMINOPROTEIN BETA-MICROSEMINOPROTEIN intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000005379.3|UniProtKB=G3QRK8 G3QRK8 CPTP PTHR10219:SF20 GLYCOLIPID TRANSFER PROTEIN-RELATED CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN phospholipid binding#GO:0005543;transporter activity#GO:0005215;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid transfer activity#GO:0120014;lipid binding#GO:0008289;lipid transfer activity#GO:0120013 cellular process#GO:0009987;cellular component organization#GO:0016043;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;ceramide transport#GO:0035627;membrane organization#GO:0061024;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000011584.3|UniProtKB=G3R7G8 G3R7G8 NKTR PTHR11071:SF257 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NK-TUMOR RECOGNITION PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000008517.3|UniProtKB=G3S1B6 G3S1B6 TEPSIN PTHR21514:SF0 AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 GORGO|Ensembl=ENSGGOG00000005049.3|UniProtKB=G3QQS6 G3QQS6 CERT1 PTHR19308:SF53 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN CERAMIDE TRANSFER PROTEIN ceramide transport#GO:0035627;lipid transport#GO:0006869;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;lipid localization#GO:0010876 GORGO|Ensembl=ENSGGOG00000015160.3|UniProtKB=G3S8D2 G3S8D2 CSN1S1 PTHR10240:SF0 ALPHA-S1-CASEIN ALPHA-S1-CASEIN response to oxygen-containing compound#GO:1901700;response to steroid hormone#GO:0048545;response to estradiol#GO:0032355;response to alcohol#GO:0097305;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to lipid#GO:0033993;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000004323.3|UniProtKB=G3QNW1 G3QNW1 CPLANE2 PTHR14983:SF1 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 2 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 2 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 GORGO|Ensembl=ENSGGOG00000038974.1|UniProtKB=A0A2I2YEV6 A0A2I2YEV6 PTHR13044:SF32 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 BZIP DOMAIN-CONTAINING PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015354.3|UniProtKB=A0A2I2YN39 A0A2I2YN39 NPHS2 PTHR10264:SF135 BAND 7 PROTEIN-RELATED PODOCIN ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 system development#GO:0048731;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;developmental process#GO:0032502;renal system development#GO:0072001;animal gross anatomical part developmental process#GO:0160108 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000022300.3|UniProtKB=A0A2I2Z1X0 A0A2I2Z1X0 SETD2 PTHR46711:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000039272.1|UniProtKB=A0A2I2YEK2 A0A2I2YEK2 PTHR12320:SF98 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE PTC7 HOMOLOG regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000009142.3|UniProtKB=G3R191 G3R191 ABLIM2 PTHR24213:SF6 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 cellular process#GO:0009987;lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000013264.3|UniProtKB=G3RBS6 G3RBS6 NSUN3 PTHR22808:SF8 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(34)-C(5))-METHYLTRANSFERASE, MITOCHONDRIAL S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000016781.3|UniProtKB=A0A2I2Z7L7 A0A2I2Z7L7 PPARD PTHR24082:SF15 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of lipid metabolic process#GO:0019216;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;multicellular organismal-level homeostasis#GO:0048871;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;hormone-mediated signaling pathway#GO:0009755;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 GORGO|Ensembl=ENSGGOG00000008065.3|UniProtKB=G3QYF5 G3QYF5 FYN PTHR24418:SF44 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FYN transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;signaling receptor binding#GO:0005102;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 immune response-activating signaling pathway#GO:0002757;cellular developmental process#GO:0048869;positive regulation of immune response#GO:0050778;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;T cell receptor signaling pathway#GO:0050852;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of immune response#GO:0050776;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;immune system process#GO:0002376;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Integrin signalling pathway#P00034>Fyn#P00942;Cadherin signaling pathway#P00012>Fyn#P00464;Parkinson disease#P00049>Src kinase#P01230;Axon guidance mediated by semaphorins#P00007>Fyn#P00335;Parkinson disease#P00049>Fyn kinase#P01235 GORGO|Ensembl=ENSGGOG00000001932.3|UniProtKB=G3QHR8 G3QHR8 VDAC3 PTHR11743:SF28 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL NON-SELECTIVE VOLTAGE-GATED ION CHANNEL VDAC3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000013560.3|UniProtKB=G3SHI8 G3SHI8 KCTD1 PTHR14499:SF65 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD1 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010689.3|UniProtKB=G3SJL8 G3SJL8 PTPN11 PTHR46559:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;phosphoric ester hydrolase activity#GO:0042578;cell adhesion molecule binding#GO:0050839;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;receptor tyrosine kinase binding#GO:0030971 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of MAPK cascade#GO:0043410;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>SHP2#P00647;CCKR signaling map#P06959>SHP-2#P07028;Interferon-gamma signaling pathway#P00035>PTP#P00960;Angiogenesis#P00005>SHP2#P00181 GORGO|Ensembl=ENSGGOG00000026408.2|UniProtKB=G3RZP4 G3RZP4 TMEM120A PTHR21433:SF1 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA TRANSMEMBRANE PROTEIN 120A cellular process#GO:0009987;developmental process#GO:0032502;fat cell differentiation#GO:0045444;cellular developmental process#GO:0048869;cell differentiation#GO:0030154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane#GO:0016020;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013107.3|UniProtKB=A0A2I2ZT63 A0A2I2ZT63 SEMA4F PTHR11036:SF72 SEMAPHORIN SEMAPHORIN-4F signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;taxis#GO:0042330;response to chemical#GO:0042221;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000016079.3|UniProtKB=G3RJ20 G3RJ20 PAN3 PTHR12272:SF11 DEADENYLATION COMPLEX SUBUNIT PAN3 PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3 nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604 catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000013426.3|UniProtKB=A0A2I2YBC0 A0A2I2YBC0 TMEM179 PTHR31872:SF4 TRANSMEMBRANE PROTEIN 179 TRANSMEMBRANE PROTEIN 179 GORGO|Ensembl=ENSGGOG00000043405.1|UniProtKB=A0A2I2YH44 A0A2I2YH44 MRPS6 PTHR21011:SF17 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000005481.3|UniProtKB=A0A2I2Z073 A0A2I2Z073 ATL1 PTHR10751:SF15 GUANYLATE BINDING PROTEIN ATLASTIN-1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;organelle organization#GO:0006996 G-protein#PC00020;heterotrimeric G-protein#PC00117 GORGO|Ensembl=ENSGGOG00000012979.3|UniProtKB=G3RB25 G3RB25 SIVA1 PTHR14365:SF1 APOPTOSIS REGULATORY PROTEIN SIVA APOPTOSIS REGULATORY PROTEIN SIVA regulation of immune response#GO:0050776;homeostasis of number of cells#GO:0048872;cell communication#GO:0007154;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;regulation of cell communication#GO:0010646;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852;negative regulation of cellular process#GO:0048523;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;multicellular organismal-level homeostasis#GO:0048871;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;immune response-regulating signaling pathway#GO:0002764;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;lymphocyte homeostasis#GO:0002260;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;negative regulation of signal transduction#GO:0009968 GORGO|Ensembl=ENSGGOG00000002963.3|UniProtKB=G3QKE0 G3QKE0 PTHR31911:SF5 PROTEIN FAM133 FAMILY WITH SEQUENCE SIMILARITY 133 MEMBER B RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009050.3|UniProtKB=G3R0Z9 G3R0Z9 NABP2 PTHR13356:SF3 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;regulation of cell cycle G2/M phase transition#GO:1902749;response to radiation#GO:0009314;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;response to abiotic stimulus#GO:0009628;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;response to ionizing radiation#GO:0010212;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000016288.3|UniProtKB=G3RJJ9 G3RJJ9 IP6K3 PTHR12400:SF40 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;alcohol biosynthetic process#GO:0046165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000038110.1|UniProtKB=A0A2I2YFL0 A0A2I2YFL0 PTHR23266:SF372 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-23-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000006480.4|UniProtKB=G3QUD8 G3QUD8 USP53 PTHR22975:SF6 UBIQUITIN SPECIFIC PROTEINASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 53 nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;system process#GO:0003008;response to external stimulus#GO:0009605;response to abiotic stimulus#GO:0009628;response to mechanical stimulus#GO:0009612;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000015807.3|UniProtKB=G3RID4 G3RID4 SORCS2 PTHR12106:SF9 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS2 transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;post-Golgi vesicle-mediated transport#GO:0006892 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005247.3|UniProtKB=G3QR97 G3QR97 EEPD1 PTHR21180:SF33 ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1 ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000015463.3|UniProtKB=G3RZ12 G3RZ12 LOC101137195 PTHR24012:SF716 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 6 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of mRNA splicing, via spliceosome#GO:0048024 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000025606.2|UniProtKB=G3S2H8 G3S2H8 ETFDH PTHR10617:SF107 ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;electron transfer activity#GO:0009055 electron transport chain#GO:0022900;metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000013374.3|UniProtKB=G3RC30 G3RC30 IK PTHR12765:SF7 RED PROTEIN IK FACTOR CYTOKINE IK PROTEIN RED RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000009642.3|UniProtKB=G3R2H1 G3R2H1 MOCOS PTHR14237:SF96 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MOLYBDENUM COFACTOR SULFURASE sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637 GORGO|Ensembl=ENSGGOG00000000400.3|UniProtKB=A0A2I2YRL9 A0A2I2YRL9 DNAJB5 PTHR24078:SF586 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 5 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000014313.3|UniProtKB=G3REG9 G3REG9 CLEC2B PTHR45710:SF15 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER B signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;regulation of immune response#GO:0050776;cell activation#GO:0001775;immune system process#GO:0002376;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;T cell activation#GO:0042110 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000009117.3|UniProtKB=G3R158 G3R158 TOX3 PTHR45781:SF3 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 3 DNA binding#GO:0003677;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000037927.1|UniProtKB=A0A2I2YU29 A0A2I2YU29 PTHR14167:SF63 SH3 DOMAIN-CONTAINING ENDOPHILIN-A2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;presynapse#GO:0098793;cytosol#GO:0005829;cytoplasm#GO:0005737;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000028528.2|UniProtKB=G3S3L4 G3S3L4 PTHR23266:SF273 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000022133.2|UniProtKB=G3RS45 G3RS45 YWHAZ PTHR18860:SF7 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA_DELTA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;PI3 kinase pathway#P00048>14-3-3#P01206;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624 GORGO|Ensembl=ENSGGOG00000039554.1|UniProtKB=A0A2I2ZIU2 A0A2I2ZIU2 HYCC2 PTHR31220:SF3 HYCCIN RELATED HYCCIN 2 glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;intracellular protein localization#GO:0008104;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;localization#GO:0051179;cellular localization#GO:0051641;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;localization within membrane#GO:0051668 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000006406.3|UniProtKB=G3QU68 G3QU68 GGT6 PTHR47278:SF1 GLUTATHIONE HYDROLASE 6 GLUTATHIONE HYDROLASE 6 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000397.3|UniProtKB=G3QDR5 G3QDR5 PHF24 PTHR46453:SF4 PROTEIN KINASE C-BINDING PROTEIN 1 PHD FINGER PROTEIN 24 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000011060.3|UniProtKB=G3R643 G3R643 MFAP3 PTHR14340:SF4 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 GORGO|Ensembl=ENSGGOG00000006516.3|UniProtKB=G3QUH6 G3QUH6 LOC101124697 PTHR24279:SF3 CYTOCHROME P450 CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME, MITOCHONDRIAL oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 regulation of biological quality#GO:0065008;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;olefinic compound metabolic process#GO:0120254;secondary alcohol metabolic process#GO:1902652;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;cellular response to hormone stimulus#GO:0032870;regulation of hormone levels#GO:0010817;response to endogenous stimulus#GO:0009719;ketone metabolic process#GO:0042180;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;steroid metabolic process#GO:0008202;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;response to nitrogen compound#GO:1901698;hormone biosynthetic process#GO:0042446;cellular response to peptide hormone stimulus#GO:0071375;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to peptide hormone#GO:0043434;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;cellular response to nitrogen compound#GO:1901699 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008525.3|UniProtKB=G3QZM6 G3QZM6 SLC38A10 PTHR22950:SF646 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 38 MEMBER 10 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000006606.3|UniProtKB=G3QUR1 G3QUR1 BTBD7 PTHR16064:SF5 BTB POZ DOMAIN CONTAINING 7 BTB_POZ DOMAIN-CONTAINING PROTEIN 7 regulation of anatomical structure morphogenesis#GO:0022603;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000007342.3|UniProtKB=A0A2I2ZD95 A0A2I2ZD95 CASP7 PTHR10454:SF31 CASPASE CASPASE-7 peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;regulation of neuron apoptotic process#GO:0043523;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>Caspase 7#P00300;FAS signaling pathway#P00020>Pro-Caspase7#P00605;FAS signaling pathway#P00020>Caspase7#P00595 GORGO|Ensembl=ENSGGOG00000013419.3|UniProtKB=G3RC66 G3RC66 CKS1B PTHR23415:SF42 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 1 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 mitotic cell cycle process#GO:1903047;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle phase transition#GO:0044772 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transferase complex#GO:1990234;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004148.3|UniProtKB=G3QNF9 G3QNF9 NUP37 PTHR22806:SF0 NUCLEOPORIN NUP37 P37 -RELATED NUCLEOPORIN NUP37 nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015190.3|UniProtKB=A0A2I2ZPQ7 A0A2I2ZPQ7 FBLIM1 PTHR24207:SF1 ZYX102 PROTEIN FILAMIN-BINDING LIM PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actomyosin#GO:0042641;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stress fiber#GO:0001725 kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000028028.2|UniProtKB=A0A2I2Z9B6 A0A2I2Z9B6 PTHR13015:SF1 PROTEIN AD-016-RELATED WASH COMPLEX SUBUNIT 3 supramolecular fiber organization#GO:0097435;secretion by cell#GO:0032940;secretion#GO:0046903;localization#GO:0051179;actin filament-based process#GO:0030029;export from cell#GO:0140352;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;actin filament organization#GO:0007015;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016418.3|UniProtKB=G3RJW7 G3RJW7 SLC16A4 PTHR11360:SF14 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 5-RELATED monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015771.3|UniProtKB=G3RI90 G3RI90 LOC101126623 PTHR23299:SF62 METALLOTHIONEIN METALLOTHIONEIN-1X ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;metal ion binding#GO:0046872;cation binding#GO:0043169 detoxification#GO:0098754;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;detoxification of inorganic compound#GO:0061687;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;response to metal ion#GO:0010038;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;response to cadmium ion#GO:0046686;homeostatic process#GO:0042592;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion homeostasis#GO:0098771;cellular response to chemical stimulus#GO:0070887 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000044152.1|UniProtKB=A0A2I2ZXK8 A0A2I2ZXK8 FAM133B PTHR31911:SF3 PROTEIN FAM133 PROTEIN FAM133B RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000022855.2|UniProtKB=A0A2I2YCN5 A0A2I2YCN5 PRMT3 PTHR11006:SF125 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 3 protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone modifying activity#GO:0140993 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000026003.2|UniProtKB=G3S5A8 G3S5A8 PTHR23271:SF2 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66 UTP6 SMALL SUBUNIT PROCESSOME COMPONENT RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613 organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009581.3|UniProtKB=G3R2B0 G3R2B0 KCTD15 PTHR14499:SF112 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL TETRAMERIZATION DOMAIN CONTAINING 15 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of membrane potential#GO:0042391 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004500.3|UniProtKB=G3QPB9 G3QPB9 CCL7 PTHR12015:SF161 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 7 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102 cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;regulation of cell motility#GO:2000145;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;response to peptide#GO:1901652;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell surface receptor signaling pathway#GO:0007166;response to stress#GO:0006950;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;taxis#GO:0042330;response to chemical#GO:0042221;response to cytokine#GO:0034097 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000023333.2|UniProtKB=A0A2I2Z9P3 A0A2I2Z9P3 CCT3 PTHR11353:SF24 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT GAMMA protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;chaperonin-containing T-complex#GO:0005832;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000004731.3|UniProtKB=G3SA98 G3SA98 MYO7B PTHR22692:SF24 MYOSIN VII, XV MYOSIN VIIB actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000026022.2|UniProtKB=A0A2I2ZB23 A0A2I2ZB23 CCDC97 PTHR31840:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 GORGO|Ensembl=ENSGGOG00000007759.3|UniProtKB=A0A2I2YI76 A0A2I2YI76 RFX4 PTHR12619:SF31 RFX TRANSCRIPTION FACTOR FAMILY TRANSCRIPTION FACTOR RFX4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000036658.1|UniProtKB=G3R1I5 G3R1I5 LOC101154318 PTHR11515:SF25 GLYCOPROTEIN HORMONE BETA CHAIN CHORIOGONADOTROPIN SUBUNIT BETA 3-RELATED receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cellular process#GO:0009987;sex differentiation#GO:0007548;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;gonad development#GO:0008406;biological regulation#GO:0065007;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;reproductive process#GO:0022414;reproductive structure development#GO:0048608;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;anatomical structure development#GO:0048856;cell communication#GO:0007154;reproductive system development#GO:0061458;female gonad development#GO:0008585;system development#GO:0048731 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000024257.2|UniProtKB=A0A2I2ZJX0 A0A2I2ZJX0 PTHR23049:SF58 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 12B myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;stress fiber#GO:0001725;membraneless organelle#GO:0043228;myosin complex#GO:0016459;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000010002.3|UniProtKB=G3RXF4 G3RXF4 FCMR PTHR11860:SF59 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN MU FC RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000011525.3|UniProtKB=G3SHK0 G3SHK0 TMCO5A PTHR22422:SF7 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5B-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5A GORGO|Ensembl=ENSGGOG00000041578.1|UniProtKB=G3S5C4 G3S5C4 CSRP2 PTHR24215:SF3 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 2 structural molecule activity#GO:0005198;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;cellular developmental process#GO:0048869;tissue development#GO:0009888 intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;I band#GO:0031674;sarcomere#GO:0030017;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;nucleus#GO:0005634;Z disc#GO:0030018;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000040755.1|UniProtKB=A0A2I2YGA4 A0A2I2YGA4 SPMAP2L PTHR15901:SF15 TESTICULAR HAPLOID EXPRESSED GENE PROTEIN SPERM MICROTUBULE ASSOCIATED PROTEIN 2-LIKE GORGO|Ensembl=ENSGGOG00000005806.3|UniProtKB=G3QSP2 G3QSP2 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014196.3|UniProtKB=G3RE63 G3RE63 WDR53 PTHR44666:SF1 WD REPEAT-CONTAINING PROTEIN 53 WD REPEAT-CONTAINING PROTEIN 53 GORGO|Ensembl=ENSGGOG00000025316.2|UniProtKB=A0A2I2Y5S6 A0A2I2Y5S6 PTHR24399:SF43 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN CONTAINING 45 sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014715.3|UniProtKB=G3RFJ2 G3RFJ2 SLCO6A1 PTHR11388:SF95 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 6A1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000017161.4|UniProtKB=G3RLT7 G3RLT7 SNX25 PTHR22775:SF48 SORTING NEXIN SORTING NEXIN-25 phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040783.1|UniProtKB=A0A2I2YP22 A0A2I2YP22 PTHR43437:SF3 HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000014909.3|UniProtKB=G3RG10 G3RG10 LOC109024475 PTHR31678:SF2 KERATIN-ASSOCIATED PROTEIN 6-3 KERATIN-ASSOCIATED PROTEIN 6-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000041002.1|UniProtKB=A0A2I2YIB6 A0A2I2YIB6 PTHR44468:SF3 COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR-RELATED COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 homotypic cell-cell adhesion#GO:0034109;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;cell-cell contact zone#GO:0044291;cell-cell junction#GO:0005911;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;intercalated disc#GO:0014704;anchoring junction#GO:0070161;basal part of cell#GO:0045178;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008738.3|UniProtKB=G3R063 G3R063 PTHR12015:SF196 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 3 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000041637.1|UniProtKB=A0A2I2YSL3 A0A2I2YSL3 LOC101133835 PTHR24012:SF409 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1 RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000023228.2|UniProtKB=G3SFV9 G3SFV9 LRRC8C PTHR24369:SF193 ANTIGEN BSP, PUTATIVE-RELATED VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8E membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000036512.1|UniProtKB=G3S8W7 G3S8W7 LOC101152850 PTHR31813:SF18 PROLINE-RICH PROTEIN 23B PROLINE-RICH PROTEIN 23B GORGO|Ensembl=ENSGGOG00000010913.3|UniProtKB=G3R5Q6 G3R5Q6 CNGA4 PTHR45638:SF2 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-4 channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;guanyl nucleotide binding#GO:0019001;gated channel activity#GO:0022836;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;purine ribonucleotide binding#GO:0032555;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076 multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;transport#GO:0006810;sensory perception#GO:0007600 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 ion channel#PC00133;ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000025008.2|UniProtKB=G3S2B6 G3S2B6 TASOR2 PTHR16207:SF10 SET DOMAIN-CONTAINING PROTEIN PROTEIN TASOR 2 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000013742.3|UniProtKB=A0A2I2ZHF6 A0A2I2ZHF6 BTG4 PTHR22978:SF5 B-CELL TRANSLOCATION GENE PROTEIN BTG4 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000003528.3|UniProtKB=G3QLV0 G3QLV0 IL1A PTHR10078:SF33 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 ALPHA cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;regulation of cell activation#GO:0050865;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of T cell proliferation#GO:0042102;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;regulation of MAPK cascade#GO:0043408;positive regulation of leukocyte activation#GO:0002696;cell surface receptor signaling pathway#GO:0007166;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of cell-cell adhesion#GO:0022409;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;regulation of multicellular organismal process#GO:0051239;response to cytokine#GO:0034097;response to chemical#GO:0042221;positive regulation of T cell activation#GO:0050870;response to lipid#GO:0033993;regulation of T cell activation#GO:0050863;inflammatory response#GO:0006954;positive regulation of lymphocyte proliferation#GO:0050671;response to bacterium#GO:0009617;cell communication#GO:0007154;positive regulation of cell adhesion#GO:0045785;response to external biotic stimulus#GO:0043207;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;regulation of leukocyte cell-cell adhesion#GO:1903037;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;response to lipopolysaccharide#GO:0032496;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;regulation of ERK1 and ERK2 cascade#GO:0070372;cellular response to lipid#GO:0071396;cytokine-mediated signaling pathway#GO:0019221;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;cellular response to biotic stimulus#GO:0071216;regulation of cell communication#GO:0010646;regulation of T cell proliferation#GO:0042129;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte proliferation#GO:0070665;defense response#GO:0006952;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;interleukin superfamily#PC00128;intercellular signal molecule#PC00207 Interleukin signaling pathway#P00036>Interleukin#P00970;Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000010736.3|UniProtKB=G3RRW7 G3RRW7 SLC4A1 PTHR11453:SF12 ANION EXCHANGE PROTEIN BAND 3 ANION TRANSPORT PROTEIN secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000008087.3|UniProtKB=G3SDE8 G3SDE8 HINFP PTHR24391:SF26 HISTONE H4 TRANSCRIPTION FACTOR-RELATED HISTONE H4 TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000040805.1|UniProtKB=A0A2I2Y9B9 A0A2I2Y9B9 PTHR11876:SF33 ALPHA-DEFENSIN 1 DEFENSIN-7 response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000003917.3|UniProtKB=A0A2I2ZRY3 A0A2I2ZRY3 PLEKHA5 PTHR12752:SF3 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 5 phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;phospholipid binding#GO:0005543;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000021946.2|UniProtKB=G3RWR4 G3RWR4 MUC15 PTHR45427:SF1 MUCIN-15 MUCIN-15 GORGO|Ensembl=ENSGGOG00000014077.3|UniProtKB=G3RTT7 G3RTT7 PNLDC1 PTHR15092:SF50 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1 3'-5'-RNA exonuclease activity#GO:0000175;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;RNA binding#GO:0003723;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA processing#GO:0006396;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000003036.3|UniProtKB=G3QKL1 G3QKL1 ASB9 PTHR24136:SF17 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 9 positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;positive regulation of metabolic process#GO:0009893;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446 GORGO|Ensembl=ENSGGOG00000010005.3|UniProtKB=G3R3G1 G3R3G1 POLE PTHR10670:SF0 DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA nuclease activity#GO:0004536;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA-directed DNA polymerase activity#GO:0003887;hydrolase activity#GO:0016787;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA exonuclease activity#GO:0004529;transferase activity#GO:0016740;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527 nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554 transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;epsilon DNA polymerase complex#GO:0008622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000016224.3|UniProtKB=G3RJD9 G3RJD9 NALF1 PTHR15819:SF9 TRANSMEMBRANE PROTEIN FAM155 NALCN CHANNEL AUXILIARY FACTOR 1 transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000002719.3|UniProtKB=G3QJS9 G3QJS9 B4GALNT3 PTHR12369:SF15 CHONDROITIN SYNTHASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000022307.2|UniProtKB=G3RUZ3 G3RUZ3 PTHR16487:SF0 PPP4R2-RELATED PROTEIN SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2 protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000012018.2|UniProtKB=A0A2I2Y6L6 A0A2I2Y6L6 KCTD16 PTHR14499:SF28 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD16 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;nervous system development#GO:0007399;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;presynaptic active zone#GO:0048786;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;presynaptic active zone membrane#GO:0048787;postsynaptic membrane#GO:0045211 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022211.2|UniProtKB=G3RQL9 G3RQL9 DEFB136 PTHR39413:SF1 BETA-DEFENSIN 136 DEFENSIN BETA 136 lipid binding#GO:0008289;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;lipopolysaccharide binding#GO:0001530 immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to fungus#GO:0050832;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000012125.3|UniProtKB=G3R8W5 G3R8W5 POLR2M PTHR23171:SF2 GDOWN1 MYOCARDIAL ZONULA ADHERENS PROTEIN membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;I band#GO:0031674;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, core complex#GO:0005665;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;contractile muscle fiber#GO:0043292;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;sarcomere#GO:0030017;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004276.3|UniProtKB=G3RE40 G3RE40 PTPN6 PTHR46257:SF4 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;protein binding#GO:0005515;binding#GO:0005488 cellular developmental process#GO:0048869;mitotic cell cycle#GO:0000278;cell differentiation#GO:0030154;cell cycle#GO:0007049;cellular process#GO:0009987;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Interferon-gamma signaling pathway#P00035>PTP#P00960;Angiogenesis#P00005>SHP2#P00181;FGF signaling pathway#P00021>SHP2#P00647;B cell activation#P00010>SHP-1#P00378 GORGO|Ensembl=ENSGGOG00000016259.3|UniProtKB=G3RJH4 G3RJH4 KIFC2 PTHR24115:SF479 KINESIN-RELATED KINESIN-LIKE PROTEIN KIFC2 ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;microtubule cytoskeleton organization involved in mitosis#GO:1902850;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;mitotic spindle organization#GO:0007052;microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;organelle assembly#GO:0070925;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226 mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000004788.3|UniProtKB=G3QQ32 G3QQ32 KPNA4 PTHR23316:SF7 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-3 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010834.3|UniProtKB=A0A2I2YQN1 A0A2I2YQN1 SCNN1A PTHR11690:SF124 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED EPITHELIAL SODIUM CHANNEL SUBUNIT ALPHA sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987 sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000006594.3|UniProtKB=G3QUP5 G3QUP5 KRT80 PTHR45616:SF1 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 80 structural molecule activity#GO:0005198 tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;skin development#GO:0043588;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;epidermis development#GO:0008544;developmental process#GO:0032502;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109 organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000010097.3|UniProtKB=G3R3M7 G3R3M7 CPEB4 PTHR12566:SF2 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;translation factor activity#GO:0180051;translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730 negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of translation#GO:0017148;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;nucleus#GO:0005634 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000004090.3|UniProtKB=A0A2I2YHN9 A0A2I2YHN9 FANCD2 PTHR32086:SF0 FANCONI ANEMIA GROUP D2 PROTEIN FANCONI ANEMIA GROUP D2 PROTEIN protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;nuclear chromosome segregation#GO:0098813;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;regulation of cellular process#GO:0050794;homologous recombination#GO:0035825;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;sexual reproduction#GO:0019953;biological regulation#GO:0065007;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;signaling#GO:0023052;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;cell cycle checkpoint signaling#GO:0000075;homologous chromosome pairing at meiosis#GO:0007129;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic DNA damage checkpoint signaling#GO:0044773;organelle fission#GO:0048285;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;meiosis I cell cycle process#GO:0061982;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;DNA integrity checkpoint signaling#GO:0031570;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;meiotic chromosome segregation#GO:0045132;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000002251.3|UniProtKB=A0A2I2ZB14 A0A2I2ZB14 CHD8 PTHR45623:SF3 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD8 ATP hydrolysis activity#GO:0016887;DNA binding#GO:0003677;hydrolase activity#GO:0016787;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;nervous system development#GO:0007399;head development#GO:0060322;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;regulation of Wnt signaling pathway#GO:0030111;negative regulation of metabolic process#GO:0009892;central nervous system development#GO:0007417;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;tube development#GO:0035295;regulation of signal transduction#GO:0009966;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004208.3|UniProtKB=G3QNL0 G3QNL0 SHROOM4 PTHR15012:SF35 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM4 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228;apical part of cell#GO:0045177;apical junction complex#GO:0043296;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000004856.3|UniProtKB=G3QQ99 G3QQ99 MYLK4 PTHR24347:SF379 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE FAMILY MEMBER 4 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000024484.2|UniProtKB=G3RR24 G3RR24 FAM13A PTHR15904:SF18 FAM13 PROTEIN FAM13A GORGO|Ensembl=ENSGGOG00000005336.3|UniProtKB=G3QRH3 G3QRH3 UBE2J2 PTHR24068:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;ERAD pathway#GO:0036503;protein modification by small protein conjugation or removal#GO:0070647;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to chemical#GO:0042221;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Ubc6#P01222 GORGO|Ensembl=ENSGGOG00000006177.3|UniProtKB=G3QTM1 G3QTM1 TMEM63C PTHR13018:SF21 PROBABLE MEMBRANE PROTEIN DUF221-RELATED OSMOSENSITIVE CATION CHANNEL TMEM63C monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000011024.3|UniProtKB=G3R606 G3R606 MBLAC1 PTHR23200:SF48 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000007022.3|UniProtKB=G3QVT5 G3QVT5 BNIP5 PTHR22435:SF0 CHROMOSOME 6 OPEN READING FRAME 222 PROTEIN BNIP5 GORGO|Ensembl=ENSGGOG00000014083.3|UniProtKB=A0A2I2Y2H9 A0A2I2Y2H9 ZNF426 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007151.3|UniProtKB=G3QW53 G3QW53 SEC14L5 PTHR23324:SF39 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 5 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000005951.3|UniProtKB=G3QT18 G3QT18 AIFM2 PTHR43735:SF27 APOPTOSIS-INDUCING FACTOR 1 FERROPTOSIS SUPPRESSOR PROTEIN 1 catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;electron transfer activity#GO:0009055 positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;cellular component organization#GO:0016043;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 p53 pathway#P00059>NOXA#G01572 GORGO|Ensembl=ENSGGOG00000027434.2|UniProtKB=A0A2I2Y221 A0A2I2Y221 PTHR11991:SF12 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of catabolic process#GO:0009895;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of autophagy#GO:0010506;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;negative regulation of programmed cell death#GO:0043069;regulation of metabolic process#GO:0019222;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000024320.2|UniProtKB=G3SF28 G3SF28 RAI14 PTHR24129:SF0 ANKYCORBIN ANKYCORBIN GORGO|Ensembl=ENSGGOG00000012994.3|UniProtKB=G3RB38 G3RB38 TIPRL PTHR21021:SF16 GAF/PUTATIVE CYTOSKELETAL PROTEIN TIP41-LIKE PROTEIN oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;molecular function activator activity#GO:0140677;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;phosphatase activator activity#GO:0019211;oxidoreductase activity#GO:0016491;phosphatase regulator activity#GO:0019208 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;TOR signaling#GO:0031929;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000012312.3|UniProtKB=G3R9F0 G3R9F0 HELZ PTHR10887:SF365 DNA2/NAM7 HELICASE FAMILY ATP-DEPENDENT RNA HELICASE WITH ZINC FINGER DOMAIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000003628.4|UniProtKB=G3QM44 G3QM44 RIMS1 PTHR12157:SF18 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 1 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of exocytosis#GO:0017157;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;cellular localization#GO:0051641;protein-containing complex assembly#GO:0065003;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;export from cell#GO:0140352;regulation of neurotransmitter secretion#GO:0046928;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;protein-containing complex organization#GO:0043933;regulation of localization#GO:0032879;exocytosis#GO:0006887;regulation of transport#GO:0051049;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;cellular component assembly#GO:0022607 presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;cell cortex#GO:0005938;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;presynaptic active zone#GO:0048786;cell junction#GO:0030054;synaptic membrane#GO:0097060 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>RIM1alpha/2alpha#P05776 GORGO|Ensembl=ENSGGOG00000042008.1|UniProtKB=A0A2I2ZDS9 A0A2I2ZDS9 PTHR22811:SF135 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN GOLD DOMAIN-CONTAINING PROTEIN cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;COPI-coated vesicle#GO:0030137;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000000440.3|UniProtKB=G3QDV6 G3QDV6 ABLIM1 PTHR24213:SF18 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 1 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031 stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Axon guidance mediated by netrin#P00009>Ablim#P00358 GORGO|Ensembl=ENSGGOG00000011624.3|UniProtKB=A0A2I2Y5P9 A0A2I2Y5P9 DMD PTHR12268:SF25 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN generation of neurons#GO:0048699;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;muscle tissue development#GO:0060537;neuron development#GO:0048666;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;regulation of biological process#GO:0050789;muscle cell development#GO:0055001;regulation of muscle system process#GO:0090257;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;neuron differentiation#GO:0030182;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;regulation of system process#GO:0044057;muscle organ development#GO:0007517;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869;skeletal muscle tissue development#GO:0007519;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;tissue development#GO:0009888;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;cell projection#GO:0042995;plasma membrane#GO:0005886;sarcolemma#GO:0042383;cell junction#GO:0030054 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002290.3|UniProtKB=A0A2I2ZY98 A0A2I2ZY98 KIZ PTHR16299:SF2 CENTROSOMAL PROTEIN KIZUNA CENTROSOMAL PROTEIN KIZUNA cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cell cycle process#GO:0022402;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000021956.2|UniProtKB=G3RX42 G3RX42 G6PC1 PTHR12591:SF3 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE CATALYTIC SUBUNIT 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 glucose metabolic process#GO:0006006;small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;monosaccharide biosynthetic process#GO:0046364;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;phosphatase#PC00181 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 GORGO|Ensembl=ENSGGOG00000013610.3|UniProtKB=A0A2I2YYJ0 A0A2I2YYJ0 ZNF713 PTHR23226:SF179 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 713 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016744.3|UniProtKB=G3RKR9 G3RKR9 CCDC18 PTHR18875:SF8 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO COILED-COIL DOMAIN-CONTAINING PROTEIN 18 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriolar satellite#GO:0034451;intracellular membraneless organelle#GO:0043232;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000036553.1|UniProtKB=A0A2I2YJZ5 A0A2I2YJZ5 IGSF23 PTHR44337:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 IMMUNOGLOBULIN SUPERFAMILY MEMBER 23 cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000024110.2|UniProtKB=G3SER7 G3SER7 RASL12 PTHR24070:SF252 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE PROTEIN FAMILY MEMBER 12 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000000780.3|UniProtKB=G3QES1 G3QES1 PTHR13482:SF3 MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8 MICROPROCESSOR COMPLEX SUBUNIT DGCR8 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723 negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;primary miRNA processing#GO:0031053;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523 endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000002594.3|UniProtKB=A0A2I2YNT5 A0A2I2YNT5 TULP3 PTHR16517:SF138 TUBBY-RELATED TUBBY-RELATED PROTEIN 3 macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365 cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006920.3|UniProtKB=A0A2I2ZRL3 A0A2I2ZRL3 LOC101129304 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025920.2|UniProtKB=A0A2I2Y8Z1 A0A2I2Y8Z1 PTHR11911:SF125 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED CBS DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000024038.2|UniProtKB=G3SJT5 G3SJT5 SSR3 PTHR13399:SF2 TRANSLOCON-ASSOCIATED PROTEIN TRAP , GAMMA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT GAMMA intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000026577.2|UniProtKB=G3SGW5 G3SGW5 FJX1 PTHR13147:SF5 FOUR-JOINTED BOX PROTEIN 1 FOUR-JOINTED BOX PROTEIN 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;cellular process#GO:0009987;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;cell communication#GO:0007154 GORGO|Ensembl=ENSGGOG00000002698.3|UniProtKB=G3QJR0 G3QJR0 ISM1 PTHR10239:SF30 ISTHMIN-2 ISTHMIN-1 regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of vasculature development#GO:1901342;regulation of angiogenesis#GO:0045765;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of angiogenesis#GO:0016525 GORGO|Ensembl=ENSGGOG00000015521.3|UniProtKB=G3RHL9 G3RHL9 ANKRD60 PTHR22677:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60 GORGO|Ensembl=ENSGGOG00000025813.2|UniProtKB=G3S7K3 G3S7K3 PTHR11334:SF22 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MRG-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043804.1|UniProtKB=A0A2I2ZGN2 A0A2I2ZGN2 SMIM10L2A PTHR34446:SF3 SMALL INTEGRAL MEMBRANE PROTEIN 10 SMALL INTEGRAL MEMBRANE PROTEIN 10-LIKE PROTEIN 2A-RELATED GORGO|Ensembl=ENSGGOG00000010691.3|UniProtKB=G3R571 G3R571 F5 PTHR24543:SF302 MULTICOPPER OXIDASE-RELATED COAGULATION FACTOR V blood coagulation#GO:0007596;regulation of biological quality#GO:0065008;wound healing#GO:0042060;system process#GO:0003008;circulatory system process#GO:0003013;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;blood circulation#GO:0008015;coagulation#GO:0050817;response to stress#GO:0006950;hemostasis#GO:0007599;response to wounding#GO:0009611 vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Blood coagulation#P00011>FVa#P00435;Blood coagulation#P00011>FV#P00432 GORGO|Ensembl=ENSGGOG00000011601.3|UniProtKB=G3R7I5 G3R7I5 SLC15A2 PTHR11654:SF603 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 2 dipeptide transmembrane transporter activity#GO:0071916;oligopeptide transmembrane transporter activity#GO:0035673;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;oligopeptide transport#GO:0006857;dipeptide transport#GO:0042938;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;localization#GO:0051179;cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;import across plasma membrane#GO:0098739 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014811.3|UniProtKB=G3RFU5 G3RFU5 DOCK11 PTHR23317:SF81 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 11 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of filopodium assembly#GO:0051489;regulation of cell projection organization#GO:0031344;regulation of response to stimulus#GO:0048583;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of cell projection assembly#GO:0060491;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000009713.3|UniProtKB=G3R2M7 G3R2M7 OR6C2 PTHR26454:SF8 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012968.3|UniProtKB=G3RB10 G3RB10 ZNF35 PTHR24377:SF1029 IP01015P-RELATED ZINC FINGER PROTEIN 135 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015752.3|UniProtKB=G3RS35 G3RS35 TBR1 PTHR11267:SF88 T-BOX PROTEIN-RELATED T-BOX BRAIN PROTEIN 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;neuron fate commitment#GO:0048663;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of cell projection organization#GO:0031344;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;forebrain development#GO:0030900;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;nervous system development#GO:0007399;head development#GO:0060322;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell fate specification#GO:0001708;neuron differentiation#GO:0030182 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 GORGO|Ensembl=ENSGGOG00000039862.1|UniProtKB=A0A2I2YHH2 A0A2I2YHH2 LOC101144999 PTHR14224:SF90 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 SUBFAMILY NOT NAMED enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 GORGO|Ensembl=ENSGGOG00000014870.3|UniProtKB=G3RFY4 G3RFY4 DENND4A PTHR12296:SF16 DENN DOMAIN-CONTAINING PROTEIN 4 C-MYC PROMOTER-BINDING PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000007226.3|UniProtKB=G3QWB5 G3QWB5 FGF18 PTHR11486:SF4 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 18 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;response to fibroblast growth factor#GO:0071774;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000014779.3|UniProtKB=G3RFQ4 G3RFQ4 EPHA4 PTHR46877:SF18 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 4 transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;system development#GO:0048731;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005493.3|UniProtKB=G3SHY1 G3SHY1 SIMC1 PTHR23187:SF3 FLJ44216 PROTEIN-RELATED SUMO-INTERACTING MOTIF-CONTAINING PROTEIN 1 peptidase inhibitor activity#GO:0030414;enzyme inhibitor activity#GO:0004857;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 organelle lumen#GO:0043233;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000010878.3|UniProtKB=G3RQ66 G3RQ66 PPP2R5C PTHR10257:SF123 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;enzyme activator activity#GO:0008047 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 GORGO|Ensembl=ENSGGOG00000028490.2|UniProtKB=G3RWP1 G3RWP1 PTHR14199:SF45 NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 6-LIKE PROTEIN NBPF FAMILY MEMBER NBPF3 GORGO|Ensembl=ENSGGOG00000027541.2|UniProtKB=G3SE82 G3SE82 CLDN10 PTHR12002:SF13 CLAUDIN CLAUDIN-10 paracellular tight junction channel activity#GO:0160187;transporter activity#GO:0005215 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;localization#GO:0051179;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;apical junction complex#GO:0043296;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000004501.3|UniProtKB=A0A2I2Z080 A0A2I2Z080 NCKAP1 PTHR12093:SF11 NCK-ASSOCIATED PROTEIN 1 NCK-ASSOCIATED PROTEIN 1 neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;anatomical structure development#GO:0048856;cortical actin cytoskeleton organization#GO:0030866;system development#GO:0048731;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell migration#GO:0016477;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009167.3|UniProtKB=G3R1A6 G3R1A6 PSMC2 PTHR23073:SF13 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 7 isomerase activity#GO:0016853;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 proteasome complex#GO:0000502;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000003250.3|UniProtKB=A0A2I2ZG31 A0A2I2ZG31 RABEPK PTHR46647:SF1 RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS GORGO|Ensembl=ENSGGOG00000000006.3|UniProtKB=G3QCR2 G3QCR2 PTHR10414:SF47 ETHANOLAMINEPHOSPHOTRANSFERASE ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000038970.1|UniProtKB=A0A2I2YFJ0 A0A2I2YFJ0 GLIS3 PTHR45718:SF1 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLIS3 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000022199.2|UniProtKB=G3S1I2 G3S1I2 SEMA6C PTHR11036:SF11 SEMAPHORIN SEMAPHORIN-6C molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000024430.2|UniProtKB=G3SHD1 G3SHD1 MKKS PTHR46787:SF1 SYNDROMES PUTATIVE CHAPERONIN-RELATED MOLECULAR CHAPERONE MKKS cilium organization#GO:0044782;chaperone-mediated protein complex assembly#GO:0051131;organelle assembly#GO:0070925;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;neuron projection#GO:0043005;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;cilium#GO:0005929;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000006526.3|UniProtKB=G3QUI0 G3QUI0 BMP15 PTHR11848:SF22 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 15 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000003401.3|UniProtKB=A0A2I2ZFJ6 A0A2I2ZFJ6 MICAL1 PTHR24206:SF59 OS06G0237300 PROTEIN [F-ACTIN]-MONOOXYGENASE MICAL1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;cellular process#GO:0009987;actin filament bundle organization#GO:0061572 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000003550.4|UniProtKB=G3QLW6 G3QLW6 ECH1 PTHR43149:SF7 ENOYL-COA HYDRATASE DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydratase#PC00120 GORGO|Ensembl=ENSGGOG00000016994.3|UniProtKB=G3RLE2 G3RLE2 RAB29 PTHR24073:SF315 DRAB5-RELATED RAS-RELATED PROTEIN RAB-29 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000008794.3|UniProtKB=G3R0B9 G3R0B9 ATP6V0A4 PTHR11629:SF26 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;enzyme binding#GO:0019899;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;monoatomic cation transmembrane transport#GO:0098655;autophagy#GO:0006914;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;process utilizing autophagic mechanism#GO:0061919;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular component disassembly#GO:0022411;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;proton transmembrane transport#GO:1902600;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;autophagosome maturation#GO:0097352;biological regulation#GO:0065007;macroautophagy#GO:0016236;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056 cell periphery#GO:0071944;brush border#GO:0005903;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;cation-transporting ATPase complex#GO:0090533;apical plasma membrane#GO:0016324;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;vacuole#GO:0005773;cytoplasm#GO:0005737;brush border membrane#GO:0031526;protein-containing complex#GO:0032991;apical part of cell#GO:0045177;proton-transporting two-sector ATPase complex#GO:0016469;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;ATPase dependent transmembrane transport complex#GO:0098533;cell projection membrane#GO:0031253 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000036258.1|UniProtKB=A0A2I2Y3G8 A0A2I2Y3G8 MRRF PTHR20982:SF10 RIBOSOME RECYCLING FACTOR RIBOSOME-RECYCLING FACTOR, MITOCHONDRIAL ribonucleoprotein complex binding#GO:0043021;ribosomal large subunit binding#GO:0043023;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488 translational termination#GO:0006415;translation#GO:0006412;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;mitochondrial gene expression#GO:0140053;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 translation release factor#PC00225 GORGO|Ensembl=ENSGGOG00000012074.3|UniProtKB=G3R8Q9 G3R8Q9 TCHHL1 PTHR47612:SF1 TRICHOHYALIN-LIKE PROTEIN 1 TRICHOHYALIN-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000009061.3|UniProtKB=G3R108 G3R108 C23H22orf15 PTHR33887:SF1 PB1 DOMAIN-CONTAINING PROTEIN GENE 867-RELATED GORGO|Ensembl=ENSGGOG00000004758.3|UniProtKB=G3QQ03 G3QQ03 YBX1 PTHR11544:SF143 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000027861.2|UniProtKB=G3SJG0 G3SJG0 INKA2 PTHR28615:SF2 PAK4-INHIBITOR INKA1-RELATED PAK4-INHIBITOR INKA2 kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010100.3|UniProtKB=G3RT42 G3RT42 DDX50 PTHR47958:SF88 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX50 RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000011594.3|UniProtKB=A0A2I2YFR4 A0A2I2YFR4 EAF2 PTHR15970:SF7 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR 2 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000028058.2|UniProtKB=G3SBK4 G3SBK4 SLC26A6 PTHR11814:SF113 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 6 monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040237.1|UniProtKB=A0A2I2ZQ85 A0A2I2ZQ85 HOXD13 PTHR45804:SF4 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-D13 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000011073.3|UniProtKB=A0A2I2YKY3 A0A2I2YKY3 LOC109026643 PTHR12682:SF14 ARCHEASE PROTEIN ARCHEASE catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000013211.3|UniProtKB=G3RBM7 G3RBM7 BMAL1 PTHR23042:SF52 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS BASIC HELIX-LOOP-HELIX ARNT-LIKE PROTEIN 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;regulation of DNA-templated transcription#GO:0006355;rhythmic process#GO:0048511;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 Circadian clock system#P00015>bmal1#G01504;Hypoxia response via HIF activation#P00030>HIF-1beta#P00820;Circadian clock system#P00015>BMAL1#P00506;Circadian clock system#P00015>bmal1#G01500 GORGO|Ensembl=ENSGGOG00000002221.3|UniProtKB=G3QZY4 G3QZY4 LOC101136299 PTHR23425:SF16 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME A-RELATED transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013636.3|UniProtKB=G3RCS0 G3RCS0 SLC22A2 PTHR24064:SF432 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 2 transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;quaternary ammonium group transmembrane transporter activity#GO:0015651;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;transport#GO:0006810;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000004964.3|UniProtKB=G3QQK5 G3QQK5 PTHR22988:SF28 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;cell division#GO:0051301;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;cortical actin cytoskeleton organization#GO:0030866;cell communication#GO:0007154;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;regulation of cell junction assembly#GO:1901888;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;multicellular organismal process#GO:0032501;mitotic cell cycle process#GO:1903047;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;signaling#GO:0023052;actomyosin structure organization#GO:0031032;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cytoskeleton-dependent cytokinesis#GO:0061640;Rho protein signal transduction#GO:0007266;cytokinesis#GO:0000910;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;embryo development#GO:0009790;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;embryonic morphogenesis#GO:0048598 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519 GORGO|Ensembl=ENSGGOG00000009585.3|UniProtKB=G3S4W5 G3S4W5 SLITRK5 PTHR45773:SF5 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 5 regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell junction assembly#GO:1901888;system development#GO:0048731;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;regulation of synapse organization#GO:0050807;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;positive regulation of cellular component biogenesis#GO:0044089;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005564.3|UniProtKB=G3RXC6 G3RXC6 GKAP1 PTHR14899:SF0 G KINASE ANCHORING PROTEIN 1 G KINASE-ANCHORING PROTEIN 1 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008603.3|UniProtKB=G3QZU2 G3QZU2 MRPS18C PTHR13479:SF57 30S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000022794.2|UniProtKB=A0A2I2ZGY9 A0A2I2ZGY9 MSRB1 PTHR46755:SF5 METHIONINE-R-SULFOXIDE REDUCTASE B1 METHIONINE-R-SULFOXIDE REDUCTASE B1 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein repair#GO:0030091;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000000402.3|UniProtKB=G3QDS0 G3QDS0 KANSL3 PTHR13136:SF16 TESTIS DEVELOPMENT PROTEIN PRTD KAT8 REGULATORY NSL COMPLEX SUBUNIT 3 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000011704.3|UniProtKB=G3R7U1 G3R7U1 COL18A1 PTHR24023:SF1034 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVIII) CHAIN-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;tube development#GO:0035295;endothelial cell differentiation#GO:0045446;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cell differentiation#GO:0030154;circulatory system development#GO:0072359;cell morphogenesis#GO:0000902;cell development#GO:0048468;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;system development#GO:0048731 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000008109.3|UniProtKB=G3QYJ3 G3QYJ3 PTHR24034:SF110 EGF-LIKE DOMAIN-CONTAINING PROTEIN PROTEIN DISULFIDE ISOMERASE CRELD2 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000004770.3|UniProtKB=G3QQ17 G3QQ17 UPK1A PTHR47110:SF4 TESTIS-SPECIFIC EXPRESSED PROTEIN 55 UROPLAKIN 1A GORGO|Ensembl=ENSGGOG00000008151.3|UniProtKB=G3QYN1 G3QYN1 SLC24A4 PTHR10846:SF21 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 4 metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;sensory perception of chemical stimulus#GO:0007606;intracellular calcium ion homeostasis#GO:0006874;system process#GO:0003008;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;homeostatic process#GO:0042592;metal ion transport#GO:0030001;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000000764.3|UniProtKB=G3RR45 G3RR45 DISP2 PTHR45951:SF2 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED HOMOLOG 2 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000043463.1|UniProtKB=A0A2I2Z283 A0A2I2Z283 PYGO1 PTHR23194:SF3 PYGOPUS PYGOPUS HOMOLOG 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;signaling#GO:0023052;gamete generation#GO:0007276;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;response to stimulus#GO:0050896;spermatid differentiation#GO:0048515;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;spermatid development#GO:0007286;sexual reproduction#GO:0019953;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulation of gene expression#GO:0010468;nucleus organization#GO:0006997;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 Wnt signaling pathway#P00057>Pygo#P01464 GORGO|Ensembl=ENSGGOG00000000665.3|UniProtKB=G3QEF9 G3QEF9 LOC101152878 PTHR24028:SF119 CADHERIN-87A PROTOCADHERIN ALPHA-C2 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000005872.3|UniProtKB=G3SAG7 G3SAG7 PTX4 PTHR19277:SF122 PENTRAXIN PENTRAXIN-4 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003877.3|UniProtKB=G3QMR2 G3QMR2 FRRS1 PTHR23130:SF115 CYTOCHROME B561 AND DOMON DOMAIN-CONTAINING PROTEIN FERRIC CHELATE REDUCTASE 1 GORGO|Ensembl=ENSGGOG00000022138.2|UniProtKB=G3SB74 G3SB74 PTHR16188:SF20 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14 protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;protein serine/threonine phosphatase inhibitor activity#GO:0004865;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678 immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000010838.3|UniProtKB=G3R5J3 G3R5J3 CHID1 PTHR46066:SF2 CHITINASE DOMAIN-CONTAINING PROTEIN 1 FAMILY MEMBER CHITINASE DOMAIN-CONTAINING PROTEIN 1 carbohydrate binding#GO:0030246;oligosaccharide binding#GO:0070492;binding#GO:0005488 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000539.3|UniProtKB=G3S6B5 G3S6B5 MTDH PTHR23251:SF0 LYSINE-RICH CEACAM1 CO-ISOLATED PROTEIN LYRIC PROTEIN PROTEIN LYRIC RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;transcription factor binding#GO:0008134;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000024376.2|UniProtKB=G3S060 G3S060 PTHR11673:SF27 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000015621.3|UniProtKB=G3R944 G3R944 FAH PTHR43069:SF2 FUMARYLACETOACETASE FUMARYLACETOACETASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;phenol-containing compound metabolic process#GO:0018958;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;monocarboxylic acid catabolic process#GO:0072329;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 GORGO|Ensembl=ENSGGOG00000034943.2|UniProtKB=G3SKT4 G3SKT4 USP40 PTHR24006:SF842 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 40 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000017026.3|UniProtKB=G3RLG7 G3RLG7 LAPTM5 PTHR12479:SF2 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 5 protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of membrane permeability#GO:0090559 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004384.3|UniProtKB=G3QP14 G3QP14 RD3 PTHR28489:SF1 RENTINAL DEGENERATION 3-LIKE PROTEIN RD3 retina development in camera-type eye#GO:0060041;visual system development#GO:0150063;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;sensory organ development#GO:0007423 GORGO|Ensembl=ENSGGOG00000000953.3|UniProtKB=G3RVV3 G3RVV3 TMEM25 PTHR47224:SF1 TRANSMEMBRANE PROTEIN 25 TRANSMEMBRANE PROTEIN 25 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of system process#GO:0044057;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794 GORGO|Ensembl=ENSGGOG00000017162.3|UniProtKB=G3RLT8 G3RLT8 BPIFA2 PTHR47145:SF1 BPI FOLD-CONTAINING FAMILY A MEMBER 2 BPI FOLD-CONTAINING FAMILY A MEMBER 2 lipid binding#GO:0008289;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;lipopolysaccharide binding#GO:0001530 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000027986.2|UniProtKB=A0A2I2ZAC4 A0A2I2ZAC4 SMIM11 PTHR35975:SF2 SMALL INTEGRAL MEMBRANE PROTEIN 11A SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000036898.1|UniProtKB=A0A2I2Y4D6 A0A2I2Y4D6 KRBOX4 PTHR23232:SF98 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000036428.1|UniProtKB=A0A2I2ZSK3 A0A2I2ZSK3 SZRD1 PTHR31796:SF4 SUZ DOMAIN-CONTAINING PROTEIN 1 SUZ RNA-BINDING DOMAIN-CONTAINING GORGO|Ensembl=ENSGGOG00000012850.3|UniProtKB=G3RAQ6 G3RAQ6 MTRFR PTHR46203:SF1 PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65 MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 translation release factor#PC00225 GORGO|Ensembl=ENSGGOG00000026710.2|UniProtKB=G3S575 G3S575 TDRD15 PTHR22948:SF7 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 15 cellular process#GO:0009987;organelle organization#GO:0006996;embryonic pattern specification#GO:0009880;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;oogenesis#GO:0048477;embryo development#GO:0009790;cellular component assembly#GO:0022607;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anterior/posterior axis specification#GO:0009948;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;developmental maturation#GO:0021700;regionalization#GO:0003002;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;spermatogenesis#GO:0007283;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;cell maturation#GO:0048469;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;sexual reproduction#GO:0019953;piRNA processing#GO:0034587;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856 cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P granule#GO:0043186 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014731.3|UniProtKB=G3RFK6 G3RFK6 PRTFDC1 PTHR43340:SF5 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE PHOSPHORIBOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;pentosyltransferase activity#GO:0016763;metal ion binding#GO:0046872;cation binding#GO:0043169;magnesium ion binding#GO:0000287 nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245;Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247 GORGO|Ensembl=ENSGGOG00000001182.3|UniProtKB=G3QFT6 G3QFT6 HHIPL2 PTHR19328:SF54 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 2 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000003490.3|UniProtKB=G3QLR7 G3QLR7 MMP13 PTHR10201:SF165 MATRIX METALLOPROTEINASE COLLAGENASE 3 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Plasminogen activating cascade#P00050>pro-MMP-13#P01254;Plasminogen activating cascade#P00050>MMP-13#P01250 GORGO|Ensembl=ENSGGOG00000014460.3|UniProtKB=G3REV5 G3REV5 PDGFRL PTHR15360:SF1 PLATELET-DERIVED GROWTH FACTOR RECEPTOR LIKE PLATELET-DERIVED GROWTH FACTOR RECEPTOR-LIKE PROTEIN tyrosine protein kinase receptor#PC00233 PDGF signaling pathway#P00047>PDGF receptor A#P01158;PDGF signaling pathway#P00047>PDGF receptor B#P01156 GORGO|Ensembl=ENSGGOG00000042348.1|UniProtKB=A0A2I2YU51 A0A2I2YU51 PTHR15231:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000010010.3|UniProtKB=G3R3E8 G3R3E8 ZBTB40 PTHR24394:SF0 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 40 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000042756.1|UniProtKB=A0A2I2YRH0 A0A2I2YRH0 PTHR34256:SF1 UPF0561 PROTEIN C2ORF68 UPF0561 PROTEIN C2ORF68 GORGO|Ensembl=ENSGGOG00000009259.3|UniProtKB=G3RSD1 G3RSD1 GTPBP8 PTHR46498:SF1 GTP-BINDING PROTEIN 8 GTP-BINDING PROTEIN 8 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000027135.2|UniProtKB=A0A2I2Y420 A0A2I2Y420 PTHR43128:SF8 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A-LIKE 6B catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000014383.3|UniProtKB=G3REN3 G3REN3 PTHR24381:SF458 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 697 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000023469.2|UniProtKB=G3S254 G3S254 LOC101152773 PTHR24062:SF199 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 1 binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010136.3|UniProtKB=G3RTX1 G3RTX1 PLSCR1 PTHR23248:SF71 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 1 intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 regulation of innate immune response#GO:0045088;establishment of localization#GO:0051234;positive regulation of response to biotic stimulus#GO:0002833;regulation of membrane lipid distribution#GO:0097035;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;lipid transport#GO:0006869;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;macromolecule localization#GO:0033036;positive regulation of innate immune response#GO:0045089;localization#GO:0051179;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;organophosphate ester transport#GO:0015748;regulation of immune system process#GO:0002682;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;regulation of response to biotic stimulus#GO:0002831;programmed cell death#GO:0012501;cell death#GO:0008219;cellular component organization or biogenesis#GO:0071840;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;endomembrane system organization#GO:0010256;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;cellular component organization#GO:0016043;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;apoptotic process#GO:0006915 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024164.2|UniProtKB=G3RTH0 G3RTH0 PKIA PTHR15416:SF2 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 kinase modulator#PC00140;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000010264.3|UniProtKB=A0A2I2Y365 A0A2I2Y365 PLEKHB2 PTHR14309:SF13 EXPRESSED PROTEIN PH DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000039954.1|UniProtKB=A0A2I2YKB0 A0A2I2YKB0 RNF217 PTHR11685:SF479 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF217 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000003590.3|UniProtKB=G3QM05 G3QM05 TMEM198 PTHR31247:SF7 TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER TRANSMEMBRANE PROTEIN 198 positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000025958.2|UniProtKB=G3S186 G3S186 RPL14 PTHR11127:SF4 60S RIBOSOMAL PROTEIN L14 LARGE RIBOSOMAL SUBUNIT PROTEIN EL14 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000680.3|UniProtKB=G3QEH5 G3QEH5 SERPINA3 PTHR11461:SF392 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-1-ANTICHYMOTRYPSIN enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 response to peptide#GO:1901652;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000034906.2|UniProtKB=A0A2I2Y4G4 A0A2I2Y4G4 FKBP7 PTHR46222:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000007241.3|UniProtKB=G3QWD1 G3QWD1 S100A5 PTHR11639:SF65 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A5 protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000024172.2|UniProtKB=A0A2I2ZQ00 A0A2I2ZQ00 ORAI3 PTHR31501:SF6 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 PROTEIN ORAI-3 calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;metal ion transport#GO:0030001;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000015716.3|UniProtKB=G3RI57 G3RI57 MCM3AP PTHR12436:SF39 80 KDA MCM3-ASSOCIATED PROTEIN GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;transcription export complex 2#GO:0070390;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007413.3|UniProtKB=G3QWU1 G3QWU1 MCOLN3 PTHR12127:SF5 MUCOLIPIN MUCOLIPIN-3 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007908.3|UniProtKB=G3QY16 G3QY16 PDCL2 PTHR45809:SF1 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 2 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000022914.2|UniProtKB=G3S951 G3S951 ZNF684 PTHR23226:SF409 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 275 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014893.3|UniProtKB=G3RFZ9 G3RFZ9 CLDN14 PTHR12002:SF99 CLAUDIN CLAUDIN-14 cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000028408.2|UniProtKB=A0A2I2Z6D6 A0A2I2Z6D6 FEM1B PTHR24173:SF78 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002451.3|UniProtKB=G3QJ32 G3QJ32 LMF1 PTHR14463:SF10 LIPASE MATURATION FACTOR LIPASE MATURATION FACTOR 1 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000002155.3|UniProtKB=G3QIB7 G3QIB7 LDB1 PTHR15528:SF5 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR-RELATED PROTEIN 1 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organismal-level homeostasis#GO:0048871;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000012895.3|UniProtKB=G3RAU9 G3RAU9 PTHR26452:SF747 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013003.3|UniProtKB=A0A2I2ZTL4 A0A2I2ZTL4 TMEM128 PTHR31134:SF1 TRANSMEMBRANE PROTEIN 128 TRANSMEMBRANE PROTEIN 128 GORGO|Ensembl=ENSGGOG00000002048.3|UniProtKB=G3RRC1 G3RRC1 MRPL39 PTHR42753:SF9 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN ML39 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000017107.3|UniProtKB=G3RLP2 G3RLP2 SEC16B PTHR13402:SF11 RGPR-RELATED PROTEIN TRANSPORT PROTEIN SEC16B organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000028520.2|UniProtKB=G3S274 G3S274 PTHR14047:SF1 P ANTIGEN FAMILY MEMBER 5-RELATED P ANTIGEN FAMILY MEMBER 3 GORGO|Ensembl=ENSGGOG00000011604.3|UniProtKB=G3R7I0 G3R7I0 CAPG PTHR11977:SF127 VILLIN MACROPHAGE-CAPPING PROTEIN protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;actin binding#GO:0003779;actin filament binding#GO:0051015;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092 regulation of anatomical structure size#GO:0090066;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex disassembly#GO:0043244;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;central nervous system development#GO:0007417;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of actin filament polymerization#GO:0030833;multicellular organismal process#GO:0032501;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;negative regulation of cytoskeleton organization#GO:0051494;anatomical structure development#GO:0048856;negative regulation of protein-containing complex disassembly#GO:0043242;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;system development#GO:0048731;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of actin filament depolymerization#GO:0030834 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 GORGO|Ensembl=ENSGGOG00000026205.2|UniProtKB=G3S539 G3S539 PTHR15298:SF16 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 1B-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000028509.2|UniProtKB=G3SGD7 G3SGD7 LOC101142199 PTHR11843:SF11 40S RIBOSOMAL PROTEIN S12 40S RIBOSOMAL PROTEIN S12 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component biogenesis#GO:0044085;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;translation#GO:0006412;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000016209.3|UniProtKB=G3RJC5 G3RJC5 LOC101131736 PTHR23192:SF34 OLFACTOMEDIN-RELATED NOELIN cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000027066.2|UniProtKB=G3SJQ7 G3SJQ7 LOC129528161 PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;chromosome organization#GO:0051276;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000017035.3|UniProtKB=G3RLH6 G3RLH6 RGS18 PTHR10845:SF155 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 18 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898 GTPase-activating protein#PC00257 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 GORGO|Ensembl=ENSGGOG00000016924.3|UniProtKB=G3RL77 G3RL77 GDF15 PTHR11848:SF78 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 15 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000001167.3|UniProtKB=G3QFS2 G3QFS2 CTSB PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000014108.3|UniProtKB=Q5NKV1 Q5NKV1 ICAM2 PTHR13771:SF3 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 2 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion mediated by integrin#GO:0033627;cell adhesion#GO:0007155;leukocyte cell-cell adhesion#GO:0007159 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000003627.3|UniProtKB=G3QM39 G3QM39 ESRP1 PTHR13976:SF37 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED EPITHELIAL SPLICING REGULATORY PROTEIN 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000025590.2|UniProtKB=A0A2I2ZJE0 A0A2I2ZJE0 PTHR10956:SF21 60S RIBOSOMAL PROTEIN L31 LARGE RIBOSOMAL SUBUNIT PROTEIN EL31 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012806.3|UniProtKB=G3RAM8 G3RAM8 MGAT5B PTHR15075:SF6 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B acetylglucosaminyltransferase activity#GO:0008375;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000003277.3|UniProtKB=G3SBF8 G3SBF8 MYL6B PTHR23048:SF5 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 6B microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;structural molecule activity#GO:0005198;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000037912.1|UniProtKB=A0A2I2YQA8 A0A2I2YQA8 PTHR11362:SF103 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000042882.1|UniProtKB=A0A2I2Y7P5 A0A2I2Y7P5 PTHR28584:SF2 FAMILY WITH SEQUENCE SIMILARITY 228 MEMBER A PROTEIN FAM228A GORGO|Ensembl=ENSGGOG00000002211.3|UniProtKB=G3QIG7 G3QIG7 HOXA2 PTHR45664:SF3 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-A2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000016808.3|UniProtKB=A0A2I2ZVW5 A0A2I2ZVW5 EIF3K PTHR13022:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000025655.2|UniProtKB=G3RZE4 G3RZE4 FAM199X PTHR32003:SF1 PROTEIN FAM199X PROTEIN FAM199X GORGO|Ensembl=ENSGGOG00000009115.3|UniProtKB=A0A2I2ZVV6 A0A2I2ZVV6 PAN2 PTHR15728:SF0 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788 regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000016592.3|UniProtKB=G3RKG1 G3RKG1 LRP2 PTHR46513:SF21 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004061.3|UniProtKB=A0A2I2YUA8 A0A2I2YUA8 HNRNPU PTHR12381:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;mRNA processing#GO:0006397;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of transcription by RNA polymerase II#GO:0006357;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000006797.3|UniProtKB=G3RNH5 G3RNH5 SUGT1 PTHR45862:SF1 PROTEIN SGT1 HOMOLOG PROTEIN SGT1 HOMOLOG GORGO|Ensembl=ENSGGOG00000005219.3|UniProtKB=G3QR74 G3QR74 ARL10 PTHR47575:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 10 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 10 GORGO|Ensembl=ENSGGOG00000013530.3|UniProtKB=G3RCH1 G3RCH1 SLC25A38 PTHR46181:SF3 MITOCHONDRIAL GLYCINE TRANSPORTER MITOCHONDRIAL GLYCINE TRANSPORTER glycine transmembrane transporter activity#GO:0015187;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;transport#GO:0006810;intracellular transport#GO:0046907;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;glycine transport#GO:0015816 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025539.2|UniProtKB=G3RSZ4 G3RSZ4 LOC101146937 PTHR12687:SF9 NUCLEOLAR COMPLEX 2 AND RAD4-RELATED SUBFAMILY NOT NAMED cellular process#GO:0009987;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686 GORGO|Ensembl=ENSGGOG00000002111.3|UniProtKB=G3QI76 G3QI76 TAF4 PTHR15138:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Huntington disease#P00029>TAFII130#P00806;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 GORGO|Ensembl=ENSGGOG00000021936.2|UniProtKB=G3SIN5 G3SIN5 LOC101127306 PTHR11442:SF50 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT DELTA heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515 erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;localization#GO:0051179;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;cellular process#GO:0009987 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 globin#PC00107;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000004800.3|UniProtKB=G3RVE5 G3RVE5 AP1G1 PTHR22780:SF26 ADAPTIN, ALPHA/GAMMA/EPSILON AP-1 COMPLEX SUBUNIT GAMMA-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;Golgi to endosome transport#GO:0006895;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;coated membrane#GO:0048475;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle coat#GO:0030120;cytoplasm#GO:0005737;clathrin-coated vesicle membrane#GO:0030665;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin vesicle coat#GO:0030125;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000009290.3|UniProtKB=A0A2I2YAH3 A0A2I2YAH3 EFNA1 PTHR11304:SF19 EPHRIN EPHRIN-A1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000014535.3|UniProtKB=G3RF20 G3RF20 SAP18 PTHR13082:SF1 SAP18 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000007481.3|UniProtKB=G3QX03 G3QX03 NOS1 PTHR19384:SF63 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE 1 ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on NAD(P)H#GO:0016651;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;monooxygenase activity#GO:0004497;carbohydrate derivative binding#GO:0097367 carboxylic acid metabolic process#GO:0019752;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;regulation of biological quality#GO:0065008;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;response to lipid#GO:0033993;response to chemical#GO:0042221;arginine metabolic process#GO:0006525;intracellular signaling cassette#GO:0141124;metabolic process#GO:0008152;response to lipopolysaccharide#GO:0032496;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to external biotic stimulus#GO:0043207;circulatory system process#GO:0003013;response to bacterium#GO:0009617;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of blood pressure#GO:0008217;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;response to other organism#GO:0051707;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;biological regulation#GO:0065007;system process#GO:0003008;response to external stimulus#GO:0009605 postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;nucleus#GO:0005634;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;plasma membrane#GO:0005886 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Gonadotropin-releasing hormone receptor pathway#P06664>NOSI#G06888;Gonadotropin-releasing hormone receptor pathway#P06664>NOSI#P06741;CCKR signaling map#P06959>NOS1#P07158 GORGO|Ensembl=ENSGGOG00000014000.3|UniProtKB=G3SAP3 G3SAP3 TYMS PTHR11548:SF2 THYMIDYLATE SYNTHASE 1 THYMIDYLATE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate biosynthetic process#GO:0009124 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 Formyltetrahydrofolate biosynthesis#P02743>Thymidylate synthase#P02954;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>Thymidylate synthase#P02913;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957 GORGO|Ensembl=ENSGGOG00000010577.3|UniProtKB=G3R4U9 G3R4U9 LOC101132466 PTHR23289:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HEME A SYNTHASE COX15 chaperone#PC00072 Vitamin D metabolism and pathway#P04396>FDX#P04607 GORGO|Ensembl=ENSGGOG00000016790.3|UniProtKB=G3RKV0 G3RKV0 CARD19 PTHR34765:SF1 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 19 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 19 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000017169.3|UniProtKB=G3RLU6 G3RLU6 NUP214 PTHR23193:SF21 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP214 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000022280.2|UniProtKB=G3S321 G3S321 ERFL PTHR11849:SF165 ETS ETS DOMAIN-CONTAINING TRANSCRIPTION FACTOR ERF-LIKE DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013019.3|UniProtKB=A0A2I2Z5X9 A0A2I2Z5X9 GFAP PTHR45652:SF9 GLIAL FIBRILLARY ACIDIC PROTEIN GLIAL FIBRILLARY ACIDIC PROTEIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;regulation of catabolic process#GO:0009894;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of protein catabolic process#GO:0042176;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;regulation of cellular process#GO:0050794;intermediate filament cytoskeleton organization#GO:0045104;regulation of macromolecule metabolic process#GO:0060255;cellular component organization#GO:0016043;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;intermediate filament#PC00129 GORGO|Gene=PTGDS|UniProtKB=Q8WNM1 Q8WNM1 PTGDS PTHR11430:SF86 LIPOCALIN PROSTAGLANDIN-H2 D-ISOMERASE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000001729.3|UniProtKB=G3RU72 G3RU72 FKBP1A PTHR10516:SF301 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859 macromolecule biosynthetic process#GO:0009059;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;biosynthetic process#GO:0009058;regulation of system process#GO:0044057;regulation of monoatomic cation transmembrane transport#GO:1904062;macromolecule metabolic process#GO:0043170;calcium-mediated signaling#GO:0019722;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;cellular response to stimulus#GO:0051716;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;regulation of heart contraction#GO:0008016;cell communication#GO:0007154;protein metabolic process#GO:0019538;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;metabolic process#GO:0008152;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;protein folding#GO:0006457;regulation of muscle contraction#GO:0006937 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;sarcoplasmic reticulum membrane#GO:0033017;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 GORGO|Ensembl=ENSGGOG00000006039.3|UniProtKB=G3QT98 G3QT98 WTAP PTHR15217:SF1 WILMS' TUMOR 1-ASSOCIATING PROTEIN PRE-MRNA-SPLICING REGULATOR WTAP enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of RNA metabolic process#GO:0051252;regulation of mRNA splicing, via spliceosome#GO:0048024;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;nucleic acid biosynthetic process#GO:0141187;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;gene expression#GO:0010467 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000025578.2|UniProtKB=G3RPE3 G3RPE3 FGF1 PTHR11486:SF86 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 1 molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to fibroblast growth factor#GO:0071774;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 growth factor#PC00112;intercellular signal molecule#PC00207 Angiogenesis#P00005>FGF#P00213;FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000026771.2|UniProtKB=G3RPN6 G3RPN6 LOC101129712 PTHR11977:SF45 VILLIN SUPERVILLIN protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543 regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000005770.3|UniProtKB=A0A2I2YKV4 A0A2I2YKV4 TSPAN14 PTHR19282:SF261 TETRASPANIN TETRASPANIN-14 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008387.3|UniProtKB=A0A2I2Y3T2 A0A2I2Y3T2 SCARB2 PTHR11923:SF118 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 LYSOSOME MEMBRANE PROTEIN 2 cargo receptor activity#GO:0038024 receptor-mediated endocytosis#GO:0006898;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;import into cell#GO:0098657;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;lysosomal transport#GO:0007041;protein localization to vacuole#GO:0072665;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;endocytosis#GO:0006897;protein localization to organelle#GO:0033365;protein localization to lysosome#GO:0061462 lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000001235.3|UniProtKB=G3QFY1 G3QFY1 TMPRSS11D PTHR24253:SF45 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11D serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000003316.3|UniProtKB=G3QLB6 G3QLB6 AGO1 PTHR22891:SF17 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-1 endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;single-stranded RNA binding#GO:0003727;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000002171.3|UniProtKB=G3QID4 G3QID4 KREMEN1 PTHR24269:SF13 KREMEN PROTEIN KREMEN PROTEIN 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Kremen#P01463 GORGO|Ensembl=ENSGGOG00000015940.3|UniProtKB=A0A2I2YSY1 A0A2I2YSY1 PTHR14234:SF21 RIM BINDING PROTEIN-RELATED RIMS-BINDING PROTEIN 3A-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular process#GO:0009987;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;spermatid development#GO:0007286;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856 microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025202.2|UniProtKB=G3RNS7 G3RNS7 LOC101133721 PTHR11467:SF14 HISTONE H1 TESTIS-SPECIFIC H1 HISTONE chromatin DNA binding#GO:0031490;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;regulation of DNA recombination#GO:0000018 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004354.3|UniProtKB=G3QNZ0 G3QNZ0 PDYN PTHR11438:SF4 PROENKEPHALIN PROENKEPHALIN-B G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;system process#GO:0003008;neuropeptide signaling pathway#GO:0007218;sensory perception of pain#GO:0019233;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;endomembrane system#GO:0012505;membrane-enclosed lumen#GO:0031974;secretory vesicle#GO:0099503;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell body#GO:0044297;vesicle#GO:0031982;organelle lumen#GO:0043233;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 intercellular signal molecule#PC00207;peptide hormone#PC00179;neuropeptide#PC00162 Enkephalin release#P05913>Enkephalin#P05976;Opioid prodynorphin pathway#P05916>prodynorphin#P05997;Opioid prodynorphin pathway#P05916>dynorphin#P06003;Enkephalin release#P05913>preproenkephalin#G06045;Enkephalin release#P05913>preproenkephalin mRNA#G06046;Opioid prodynorphin pathway#P05916>preprodynorphin#G06049;Opioid proenkephalin pathway#P05915>Enkephalin#P05991;Opioid prodynorphin pathway#P05916>preprodynorphin#G06047 GORGO|Ensembl=ENSGGOG00000003792.3|UniProtKB=G3QMI5 G3QMI5 ZMAT5 PTHR16465:SF0 NUCLEASE-RELATED ZINC FINGER MATRIN-TYPE PROTEIN 5 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000013215.3|UniProtKB=G3RBN6 G3RBN6 GLG1 PTHR11884:SF1 SELECTIN LIGAND RELATED GOLGI APPARATUS PROTEIN 1 binding#GO:0005488;growth factor binding#GO:0019838;protein binding#GO:0005515;fibroblast growth factor binding#GO:0017134 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013194.3|UniProtKB=G3S672 G3S672 LOC101126280 PTHR24028:SF55 CADHERIN-87A PROTOCADHERIN BETA-4 cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000025087.2|UniProtKB=G3S0S5 G3S0S5 OXCT1 PTHR13707:SF30 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID COENZYME A TRANSFERASE 1, MITOCHONDRIAL transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000813.3|UniProtKB=G3QEU9 G3QEU9 LMNA PTHR45721:SF5 LAMIN DM0-RELATED PRELAMIN-A_C structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cellular localization#GO:0051641;negative regulation of biosynthetic process#GO:0009890;membrane organization#GO:0061024;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;protein localization to nucleus#GO:0034504;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;transport#GO:0006810;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;localization#GO:0051179;localization within membrane#GO:0051668;organelle localization#GO:0051640 intracellular organelle#GO:0043229;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 FAS signaling pathway#P00020>Nuclear Lamin#P00616 GORGO|Ensembl=ENSGGOG00000011103.3|UniProtKB=G3R679 G3R679 VTN PTHR22917:SF3 HEMOPEXIN DOMAIN-CONTAINING PROTEIN VITRONECTIN protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;extracellular matrix binding#GO:0050840;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell adhesion mediated by integrin#GO:0033627;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 GORGO|Ensembl=ENSGGOG00000009188.3|UniProtKB=G3R1C9 G3R1C9 CAMTA2 PTHR23335:SF9 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 2 nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000013251.3|UniProtKB=A0A2I2YYT6 A0A2I2YYT6 QRICH1 PTHR45736:SF8 ZINC FINGER MYM-TYPE PROTEIN TRANSCRIPTIONAL REGULATOR QRICH1 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000004565.3|UniProtKB=A0A2I2ZIR7 A0A2I2ZIR7 TMEM97 PTHR31204:SF1 SIGMA INTRACELLULAR RECEPTOR 2 SIGMA INTRACELLULAR RECEPTOR 2 regulation of cellular process#GO:0050794;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of biological process#GO:0050789 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000012416.3|UniProtKB=G3RVE1 G3RVE1 ECPAS PTHR23346:SF19 TRANSLATIONAL ACTIVATOR GCN1-RELATED PROTEASOME ADAPTER AND SCAFFOLD PROTEIN ECM29 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026760.2|UniProtKB=G3SB22 G3SB22 HNRNPD PTHR48033:SF3 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008355.3|UniProtKB=G3QZ63 G3QZ63 PTHR24103:SF716 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 64-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000027030.2|UniProtKB=G3S4L1 G3S4L1 PTHR24340:SF40 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000006494.3|UniProtKB=G3QUF5 G3QUF5 CCDC69 PTHR24200:SF6 TOUCAN, ISOFORM A COILED-COIL DOMAIN-CONTAINING PROTEIN 69 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000006667.3|UniProtKB=G3S780 G3S780 PTHR13025:SF2 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN D2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000041895.1|UniProtKB=A0A2I2Z2P8 A0A2I2Z2P8 PTHR11721:SF16 60S RIBOSOMAL PROTEIN L27A LARGE RIBOSOMAL SUBUNIT PROTEIN UL15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011002.3|UniProtKB=G3S8V6 G3S8V6 TMC1 PTHR23302:SF18 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267 response to external stimulus#GO:0009605;system process#GO:0003008;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of mechanical stimulus#GO:0050982;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;response to mechanical stimulus#GO:0009612;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000009313.3|UniProtKB=G3R1M7 G3R1M7 TOP1MT PTHR10290:SF1 DNA TOPOISOMERASE I DNA TOPOISOMERASE I, MITOCHONDRIAL isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle process#GO:0022402;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoid#GO:0009295;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;mitochondrion#GO:0005739;mitochondrial nucleoid#GO:0042645;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 DNA topoisomerase#PC00017;DNA metabolism protein#PC00009 DNA replication#P00017>DNA Topisomerase#P00536 GORGO|Ensembl=ENSGGOG00000013545.3|UniProtKB=G3RCI4 G3RCI4 SIRPB2 PTHR19971:SF9 SIGNAL-REGULATORY PROTEIN BETA SIGNAL-REGULATORY PROTEIN BETA-2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037959.1|UniProtKB=A0A2I2YDM8 A0A2I2YDM8 PTHR19433:SF121 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 6 response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000017130.3|UniProtKB=A0A2I2Z905 A0A2I2Z905 CNGB1 PTHR45638:SF16 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL BETA-1 channel activity#GO:0015267;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;purine ribonucleotide binding#GO:0032555;monoatomic ion channel activity#GO:0005216;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215 multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;monoatomic ion transmembrane transport#GO:0034220;homeostatic process#GO:0042592;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;retina homeostasis#GO:0001895;monoatomic cation transport#GO:0006812;multicellular organismal-level homeostasis#GO:0048871;monoatomic ion transport#GO:0006811;tissue homeostasis#GO:0001894;transport#GO:0006810 transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;membrane protein complex#GO:0098796 ion channel#PC00133;ligand-gated ion channel#PC00141 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 GORGO|Ensembl=ENSGGOG00000008887.3|UniProtKB=G3R0K3 G3R0K3 FMO2 PTHR23023:SF84 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000005685.3|UniProtKB=G3QSD0 G3QSD0 AMER3 PTHR22237:SF2 APC MEMBRANE RECRUITMENT PROTEIN 2-RELATED APC MEMBRANE RECRUITMENT PROTEIN 3 protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000015737.3|UniProtKB=A0A2I2YS62 A0A2I2YS62 WDSUB1 PTHR46573:SF1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000010273.3|UniProtKB=G3SB35 G3SB35 HECTD2 PTHR45622:SF56 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD2-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 GORGO|Ensembl=ENSGGOG00000004662.3|UniProtKB=G3S5J8 G3S5J8 NLRP5 PTHR45690:SF7 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 5 biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of response to stress#GO:0080134 cell cortex#GO:0005938;mitochondrion#GO:0005739;nucleus#GO:0005634;cell periphery#GO:0071944;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000007153.3|UniProtKB=G3QW49 G3QW49 CHRNB2 PTHR18945:SF901 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-2 postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;synaptic signaling#GO:0099536;response to chemical#GO:0042221 postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNB2#P06613;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095 GORGO|Ensembl=ENSGGOG00000015201.3|UniProtKB=G3RGS7 G3RGS7 CCN4 PTHR11348:SF4 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 4 integrin binding#GO:0005178;carbohydrate derivative binding#GO:0097367;cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539 positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;cell adhesion#GO:0007155;signaling#GO:0023052;regulation of developmental process#GO:0050793;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 GORGO|Ensembl=ENSGGOG00000000851.4|UniProtKB=A0A2I2YTE1 A0A2I2YTE1 CD44 PTHR10225:SF6 HYALURONAN RECEPTOR CD44 ANTIGEN molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;transmembrane signaling receptor activity#GO:0004888;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;defense response#GO:0006952;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell adhesion#GO:0007155;inflammatory response#GO:0006954;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056 plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>CD44#P00145;Alzheimer disease-presenilin pathway#P00004>CD44 intracellular fragment#P00121;Alzheimer disease-presenilin pathway#P00004>CD44 C-terminal fragment#P00123;Alzheimer disease-presenilin pathway#P00004>CD44 N-terminal fragment#P00174;Alzheimer disease-presenilin pathway#P00004>CD44 transmembrane fragment#P00167 GORGO|Ensembl=ENSGGOG00000006850.3|UniProtKB=G3SD94 G3SD94 MDN1 PTHR48103:SF2 MIDASIN-RELATED MIDASIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;protein-RNA complex assembly#GO:0022618;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;ribosomal large subunit assembly#GO:0000027;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000013456.3|UniProtKB=G3RCB3 G3RCB3 TRIM24 PTHR45915:SF4 TRANSCRIPTION INTERMEDIARY FACTOR TRANSCRIPTION INTERMEDIARY FACTOR 1-ALPHA transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;transcription coactivator activity#GO:0003713;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;transcription regulator activity#GO:0140110;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of protein stability#GO:0031647;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000002535.3|UniProtKB=G3S1X4 G3S1X4 ATP2C1 PTHR42861:SF2 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 1 P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829 calcium ion homeostasis#GO:0055074;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000002480.3|UniProtKB=A0A2I2Z112 A0A2I2Z112 UNC50 PTHR12841:SF6 PROTEIN UNC-50 HOMOLOG PROTEIN UNC-50 HOMOLOG intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000015990.3|UniProtKB=G3RIT0 G3RIT0 ZDHHC24 PTHR22883:SF414 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC24-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000039747.1|UniProtKB=A0A2I2ZVX0 A0A2I2ZVX0 CIAO1 PTHR19920:SF0 WD40 PROTEIN CIAO1 CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000014689.3|UniProtKB=G3RFG4 G3RFG4 TFF1 PTHR13826:SF18 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 1 digestion#GO:0007586;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;tissue homeostasis#GO:0001894;system process#GO:0003008;multicellular organismal-level homeostasis#GO:0048871 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CCKR signaling map#P06959>TFF1#G07287;CCKR signaling map#P06959>TFF1#G06993 GORGO|Ensembl=ENSGGOG00000011605.3|UniProtKB=A0A2I2ZWA3 A0A2I2ZWA3 SPTBN1 PTHR11915:SF226 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular process#GO:0009987;organelle organization#GO:0006996;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;localization within membrane#GO:0051668;actin filament-based process#GO:0030029;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular localization#GO:0051641 membrane#GO:0016020;cell periphery#GO:0071944;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000016095.3|UniProtKB=G3RJ29 G3RJ29 MRPS30 PTHR13014:SF3 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S30/P52 PRO-APOTOTIC PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML65 organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000025972.2|UniProtKB=G3SHQ9 G3SHQ9 ZDHHC6 PTHR22883:SF23 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC6 catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023051.2|UniProtKB=G3RRP1 G3RRP1 PTHR46559:SF6 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 PROTEIN TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 11 kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;cell adhesion molecule binding#GO:0050839;phosphoric ester hydrolase activity#GO:0042578;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;receptor tyrosine kinase binding#GO:0030971;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000028258.2|UniProtKB=G3RNF2 G3RNF2 PTHR13080:SF10 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED SUBFAMILY NOT NAMED proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324 purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;oxidative phosphorylation#GO:0006119;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117 cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000010959.3|UniProtKB=G3R5U9 G3R5U9 ATXN7L3 PTHR46367:SF1 ATAXIN-7-LIKE PROTEIN 3 ATAXIN-7-LIKE PROTEIN 3 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;DUBm complex#GO:0071819;SAGA complex#GO:0000124;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 GORGO|Ensembl=ENSGGOG00000005292.3|UniProtKB=G3QRD6 G3QRD6 EGR2 PTHR23235:SF54 KRUEPPEL-LIKE TRANSCRIPTION FACTOR E3 SUMO-PROTEIN LIGASE EGR2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012699.3|UniProtKB=G3RAB9 G3RAB9 ZNF367 PTHR23235:SF130 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 367 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003450.3|UniProtKB=G3QLN8 G3QLN8 TNS3 PTHR45734:SF5 TENSIN TENSIN-3 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000041714.1|UniProtKB=A0A2I2YYP2 A0A2I2YYP2 SERTAD3 PTHR15530:SF0 SERTA DOMAIN-CONTAINING PROTEIN 3 SERTA DOMAIN-CONTAINING PROTEIN 3 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000034964.2|UniProtKB=G3SKV8 G3SKV8 SPATA6L PTHR16435:SF5 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 SPERMATOGENESIS ASSOCIATED 6-LIKE PROTEIN GORGO|Ensembl=ENSGGOG00000015313.3|UniProtKB=G3S272 G3S272 HSPH1 PTHR45639:SF2 HSC70CB, ISOFORM G-RELATED HEAT SHOCK PROTEIN 105 KDA molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589 protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp70 family chaperone#PC00027 GORGO|Ensembl=ENSGGOG00000009845.3|UniProtKB=A0A2I2ZD98 A0A2I2ZD98 LOC101141509 PTHR48001:SF177 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7A5 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043331.1|UniProtKB=G3RN81 G3RN81 MYH2 PTHR45615:SF39 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-2 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657 system process#GO:0003008;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;muscle contraction#GO:0006936 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 GORGO|Ensembl=ENSGGOG00000008197.3|UniProtKB=A0A2I2YDD3 A0A2I2YDD3 TSEN34 PTHR13070:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34 phosphorus-oxygen lyase activity#GO:0016849;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;lyase activity#GO:0016829 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000041428.1|UniProtKB=A0A2I2Y962 A0A2I2Y962 PTHR12606:SF30 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190 GORGO|Ensembl=ENSGGOG00000043593.1|UniProtKB=A0A2I2ZQV4 A0A2I2ZQV4 ZNF471 PTHR24377:SF951 IP01015P-RELATED ZINC FINGER PROTEIN 471 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003893.3|UniProtKB=G3QMS2 G3QMS2 ENKD1 PTHR21490:SF2 ENKURIN-RELATED ENKURIN DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000026438.2|UniProtKB=G3RVJ7 G3RVJ7 GPR180 PTHR23252:SF29 INTIMAL THICKNESS RECEPTOR-RELATED INTEGRAL MEMBRANE PROTEIN GPR180 GORGO|Ensembl=ENSGGOG00000038921.1|UniProtKB=A0A2I2YSY6 A0A2I2YSY6 SGO2 PTHR21577:SF3 SHUGOSHIN SHUGOSHIN 2 chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic sister chromatid cohesion#GO:0051177;meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;mitotic sister chromatid cohesion#GO:0007064;cellular process#GO:0009987;organelle organization#GO:0006996;organelle fission#GO:0048285;sister chromatid cohesion#GO:0007062;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle#GO:0007049 cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229 centromere DNA-binding protein#PC00071 GORGO|Ensembl=ENSGGOG00000024999.2|UniProtKB=A0A2I2Z161 A0A2I2Z161 ATRX PTHR46357:SF1 TRANSCRIPTIONAL REGULATOR ATRX CHROMATIN REMODELER ATRX DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;replication fork processing#GO:0031297;chromatin remodeling#GO:0006338;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000014503.3|UniProtKB=G3REZ1 G3REZ1 LRFN4 PTHR24366:SF84 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 4 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000025726.2|UniProtKB=G3RVV7 G3RVV7 LOC101150633 PTHR10796:SF60 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 3 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000011269.3|UniProtKB=G3R6M5 G3R6M5 WNT10B PTHR12027:SF76 WNT RELATED PROTEIN WNT-10B signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206 GORGO|Ensembl=ENSGGOG00000007121.3|UniProtKB=G3QW18 G3QW18 GPHB5 PTHR11515:SF14 GLYCOPROTEIN HORMONE BETA CHAIN GLYCOPROTEIN HORMONE BETA-5 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 GORGO|Gene=OR1D5|UniProtKB=Q9TU90 Q9TU90 OR1D5 PTHR48001:SF70 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1D4-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003908.3|UniProtKB=A0A2I2ZMX8 A0A2I2ZMX8 MTCH1 PTHR10780:SF3 MITOCHONDRIAL CARRIER HOMOLOG MITOCHONDRIAL CARRIER HOMOLOG 1 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 regulation of apoptotic process#GO:0042981;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;positive regulation of cellular process#GO:0048522;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;membrane organization#GO:0061024;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;protein insertion into membrane#GO:0051205;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000041226.1|UniProtKB=G3RPR5 G3RPR5 EPO PTHR10370:SF1 ERYTHROPOIETIN ERYTHROPOIETIN enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;signaling receptor activator activity#GO:0030546;protein kinase regulator activity#GO:0019887;cytokine activity#GO:0005125;binding#GO:0005488;cytokine receptor binding#GO:0005126;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;signaling receptor binding#GO:0005102;hormone activity#GO:0005179 cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway via STAT#GO:0097696;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;response to cytokine#GO:0034097;response to chemical#GO:0042221;homeostasis of number of cells#GO:0048872;cytokine-mediated signaling pathway#GO:0019221;immune system process#GO:0002376;response to peptide#GO:1901652;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cell development#GO:0048468;homeostatic process#GO:0042592;signaling#GO:0023052;myeloid cell differentiation#GO:0030099;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000009017.3|UniProtKB=G3R0X1 G3R0X1 RUSC2 PTHR15591:SF14 RUN AND SH3 DOMAIN CONTAINING AP-4 COMPLEX ACCESSORY SUBUNIT RUSC2 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000000955.3|UniProtKB=A0A2I2Y5V2 A0A2I2Y5V2 ZNF461 PTHR24377:SF277 IP01015P-RELATED ZINC FINGER PROTEIN 461 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003092.3|UniProtKB=G3QKQ9 G3QKQ9 LXN PTHR28591:SF1 LATEXIN LATEXIN peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000003191.3|UniProtKB=G3RTX2 G3RTX2 ASPDH PTHR24369:SF102 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488 regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;synaptic membrane adhesion#GO:0099560;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;positive regulation of cellular component biogenesis#GO:0044089;regulation of multicellular organismal process#GO:0051239;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;regulation of cell junction assembly#GO:1901888;synapse organization#GO:0050808;regulation of synapse assembly#GO:0051963;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;positive regulation of synapse assembly#GO:0051965;positive regulation of developmental process#GO:0051094 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000005837.3|UniProtKB=G3QSR8 G3QSR8 CFAP95 PTHR35069:SF1 PROTEIN C9ORF135 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 95 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000013436.3|UniProtKB=G3RC83 G3RC83 PLA2G7 PTHR10272:SF12 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001951.4|UniProtKB=G3QHT4 G3QHT4 SLC22A3 PTHR24064:SF52 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000005236.3|UniProtKB=G3QR85 G3QR85 PTHR11437:SF24 RIBONUCLEASE RIBONUCLEASE PANCREATIC catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 response to external stimulus#GO:0009605;defense response#GO:0006952;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000011796.3|UniProtKB=A0A2I2YIC9 A0A2I2YIC9 SIPA1 PTHR15711:SF14 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED PROTEIN 1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000015893.3|UniProtKB=G3RIJ8 G3RIJ8 IFIH1 PTHR14074:SF14 HELICASE WITH DEATH DOMAIN-RELATED INTERFERON-INDUCED HELICASE C DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;nucleic acid binding#GO:0003676;binding#GO:0005488;small molecule binding#GO:0036094;double-stranded RNA binding#GO:0003725;transition metal ion binding#GO:0046914;single-stranded RNA binding#GO:0003727;zinc ion binding#GO:0008270 cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;immune system process#GO:0002376;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;defense response to virus#GO:0051607;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;signal transduction#GO:0007165;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to virus#GO:0009615;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;response to external biotic stimulus#GO:0043207;intracellular receptor signaling pathway#GO:0030522;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;antiviral innate immune response#GO:0140374;innate immune response-activating signaling pathway#GO:0002758;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000015770.3|UniProtKB=G3RI93 G3RI93 GLUD1 PTHR11606:SF25 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 GORGO|Ensembl=ENSGGOG00000013492.3|UniProtKB=G3RCE4 G3RCE4 UNC13B PTHR10480:SF8 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG B binding#GO:0005488;SNARE binding#GO:0000149;calmodulin binding#GO:0005516;protein binding#GO:0005515;syntaxin binding#GO:0019905 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;vesicle localization#GO:0051648;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;calcium-ion regulated exocytosis#GO:0017156;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic transmission, glutamatergic#GO:0035249;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;signaling#GO:0023052;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;secretion by cell#GO:0032940;cellular localization#GO:0051641 organelle membrane#GO:0031090;axon terminus#GO:0043679;neuromuscular junction#GO:0031594;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;distal axon#GO:0150034;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306;synaptic membrane#GO:0097060;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular vesicle#GO:0097708;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Synaptic vesicle trafficking#P05734>Munc13#P05773 GORGO|Ensembl=ENSGGOG00000043960.1|UniProtKB=G3RRM8 G3RRM8 PTHR15438:SF14 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER A1-RELATED GORGO|Ensembl=ENSGGOG00000038936.1|UniProtKB=A0A2I2Y767 A0A2I2Y767 PTHR23037:SF49 CYTOKINE RECEPTOR SUBFAMILY NOT NAMED protein binding#GO:0005515;molecular transducer activity#GO:0060089;growth factor binding#GO:0019838;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 interleukin-9-mediated signaling pathway#GO:0038113;biological regulation#GO:0065007;adaptive immune response#GO:0002250;response to chemical#GO:0042221;response to cytokine#GO:0034097;signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;immunoglobulin mediated immune response#GO:0016064;response to peptide#GO:1901652;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell communication#GO:0007154;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune system process#GO:0002376;cytokine-mediated signaling pathway#GO:0019221 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002087.3|UniProtKB=G3QI56 G3QI56 LRP6 PTHR46513:SF40 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6 system development#GO:0048731;nervous system development#GO:0007399;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>LRP5/6#P01431;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 GORGO|Ensembl=ENSGGOG00000008824.3|UniProtKB=G3S0E3 G3S0E3 PTHR45689:SF4 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 4 voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655 plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;transporter complex#GO:1990351;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015612.3|UniProtKB=G3RHV2 G3RHV2 CDIPT PTHR15362:SF4 PHOSPHATIDYLINOSITOL SYNTHASE CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000008703.2|UniProtKB=G3R030 G3R030 LOC101140244 PTHR12638:SF3 PROTEIN MAGO NASHI HOMOLOG MAGOH negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;nuclear mRNA surveillance#GO:0071028;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 GORGO|Ensembl=ENSGGOG00000027684.2|UniProtKB=G3S062 G3S062 INSL5 PTHR20968:SF2 ILGF DOMAIN-CONTAINING PROTEIN INSULIN-LIKE PEPTIDE INSL5 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of multicellular organismal process#GO:0051239;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;positive regulation of signal transduction#GO:0009967;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 GORGO|Ensembl=ENSGGOG00000014616.3|UniProtKB=G3RF95 G3RF95 SETD9 PTHR33524:SF2 C5ORF35 SET DOMAIN-CONTAINING PROTEIN 9 GORGO|Ensembl=ENSGGOG00000028262.2|UniProtKB=G3SC09 G3SC09 PTHR11758:SF37 40S RIBOSOMAL PROTEIN S15A SMALL RIBOSOMAL SUBUNIT PROTEIN US8 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010239.3|UniProtKB=G3R405 G3R405 NTS PTHR15356:SF0 NEUROTENSIN/NEUROMEDIN N NEUROTENSIN_NEUROMEDIN N molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218 axon terminus#GO:0043679;cell junction#GO:0030054;axon#GO:0030424;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection terminus#GO:0044306;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;presynapse#GO:0098793 GORGO|Ensembl=ENSGGOG00000016520.3|UniProtKB=G3RK58 G3RK58 PTPN7 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011251.3|UniProtKB=G3R6M0 G3R6M0 ARHGAP45 PTHR15228:SF18 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 45 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000003280.4|UniProtKB=A0A2I2Z9S1 A0A2I2Z9S1 PEX5 PTHR10130:SF2 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR signal sequence receptor activity#GO:0005048;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;cellular component organization#GO:0016043;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;peroxisomal transport#GO:0043574;peroxisome organization#GO:0007031 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;cytosol#GO:0005829;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013412.2|UniProtKB=G3RC54 G3RC54 ACTRT3 PTHR11937:SF159 ACTIN ACTIN-RELATED PROTEIN T3 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin and actin related protein#PC00039 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944 GORGO|Ensembl=ENSGGOG00000000241.3|UniProtKB=G3QDC6 G3QDC6 SERPINF1 PTHR11461:SF84 SERINE PROTEASE INHIBITOR, SERPIN PIGMENT EPITHELIUM-DERIVED FACTOR peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of vasculature development#GO:1901342;regulation of angiogenesis#GO:0045765;negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000016712.3|UniProtKB=G3RKN3 G3RKN3 PHKG2 PTHR24347:SF390 SERINE/THREONINE-PROTEIN KINASE PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, LIVER_TESTIS ISOFORM protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;energy reserve metabolic process#GO:0006112;response to stimulus#GO:0050896;polysaccharide metabolic process#GO:0005976;regulation of cellular process#GO:0050794;signaling#GO:0023052;carbohydrate metabolic process#GO:0005975;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 GORGO|Ensembl=ENSGGOG00000042115.1|UniProtKB=A0A2I2ZZ53 A0A2I2ZZ53 LOC109027306 PTHR23428:SF385 HISTONE H2B HISTONE H2B TYPE 1-C_E_F_G_I response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000016309.3|UniProtKB=G3RJL7 G3RJL7 PACSIN2 PTHR23065:SF14 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 2 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;cytoskeleton organization#GO:0007010;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000008006.3|UniProtKB=G3QY98 G3QY98 APOA1 PTHR18976:SF11 APOLIPOPROTEIN APOLIPOPROTEIN A-I enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;binding#GO:0005488;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;cholesterol transfer activity#GO:0120020;molecular function regulator activity#GO:0098772;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;sterol transfer activity#GO:0120015;transporter activity#GO:0005215 small molecule metabolic process#GO:0044281;organophosphate ester transport#GO:0015748;homeostatic process#GO:0042592;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;lipid transport#GO:0006869;steroid metabolic process#GO:0008202;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;cellular process#GO:0009987;cholesterol efflux#GO:0033344;sterol metabolic process#GO:0016125;sterol transport#GO:0015918;establishment of localization#GO:0051234;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;transport#GO:0006810;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203 vesicle#GO:0031982;very-low-density lipoprotein particle#GO:0034361;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;lipoprotein particle#GO:1990777;protein-lipid complex#GO:0032994;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;high-density lipoprotein particle#GO:0034364;membrane-bounded organelle#GO:0043227;plasma lipoprotein particle#GO:0034358 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000000660.4|UniProtKB=G3QEF6 G3QEF6 C8H10orf67 PTHR22382:SF7 RIKEN CDNA 4921504E06 GENE RIKEN CDNA 4921504E06 GENE GORGO|Ensembl=ENSGGOG00000013837.3|UniProtKB=G3RDA2 G3RDA2 TOR1AIP1 PTHR18843:SF6 TORSIN-1A-INTERACTING PROTEIN TORSIN-1A-INTERACTING PROTEIN 1 nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;nuclear envelope organization#GO:0006998;cellular component organization#GO:0016043;organelle organization#GO:0006996;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;membrane organization#GO:0061024;endomembrane system organization#GO:0010256 membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000041159.1|UniProtKB=A0A2I2ZUP7 A0A2I2ZUP7 PTHR23267:SF527 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-21 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000001394.3|UniProtKB=G3QGC2 G3QGC2 TTC9B PTHR11242:SF13 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 9B metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000028051.2|UniProtKB=G3S355 G3S355 PTHR19969:SF22 SH2-SH3 ADAPTOR PROTEIN-RELATED GRB2-RELATED ADAPTER PROTEIN-LIKE receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;signaling receptor binding#GO:0005102 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell migration#GO:0016477;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000017196.3|UniProtKB=G3RLW9 G3RLW9 PREP PTHR42881:SF2 PROLYL ENDOPEPTIDASE PROLYL ENDOPEPTIDASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 Vasopressin synthesis#P04395>Endo Peptidase#P04596 GORGO|Ensembl=ENSGGOG00000016345.3|UniProtKB=G3RJQ4 G3RJQ4 TNR PTHR19143:SF254 FIBRINOGEN/TENASCIN/ANGIOPOEITIN TENASCIN-R animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000009974.3|UniProtKB=G3R3B3 G3R3B3 PTHR15237:SF1 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9A response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of cell cycle#GO:0045786;cellular response to abiotic stimulus#GO:0071214;DNA replication checkpoint signaling#GO:0000076;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;response to abiotic stimulus#GO:0009628;signal transduction in response to DNA damage#GO:0042770;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;signaling#GO:0023052;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of mitotic cell cycle#GO:0045930;DNA integrity checkpoint signaling#GO:0031570;mitotic DNA integrity checkpoint signaling#GO:0044774;response to radiation#GO:0009314;regulation of mitotic cell cycle#GO:0007346;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 exodeoxyribonuclease#PC00098 GORGO|Ensembl=ENSGGOG00000024925.2|UniProtKB=A0A2I2ZCG4 A0A2I2ZCG4 PTHR23339:SF65 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 2 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012251.3|UniProtKB=A0A2I2ZXZ0 A0A2I2ZXZ0 CAMKV PTHR24347:SF18 SERINE/THREONINE-PROTEIN KINASE CAM KINASE-LIKE VESICLE-ASSOCIATED PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000042224.1|UniProtKB=A0A2I2Z426 A0A2I2Z426 PTHR23064:SF29 TROPONIN PARVALBUMIN-LIKE EF-HAND-CONTAINING PROTEIN nervous system process#GO:0050877;muscle contraction#GO:0006936;neuromuscular process#GO:0050905;system process#GO:0003008;muscle system process#GO:0003012;striated muscle contraction#GO:0006941;skeletal muscle contraction#GO:0003009;multicellular organismal process#GO:0032501 myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cytoskeleton#GO:0005856;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000022832.2|UniProtKB=A0A2I2ZX18 A0A2I2ZX18 PTHR11960:SF34 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000041318.1|UniProtKB=A0A2I2Y3H9 A0A2I2Y3H9 PTHR15487:SF6 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000012760.3|UniProtKB=A0A2I2YDK2 A0A2I2YDK2 C2H3orf49 PTHR36473:SF1 CHROMOSOME 3 OPEN READING FRAME 49 GENE 11100-RELATED GORGO|Ensembl=ENSGGOG00000001528.3|UniProtKB=A0A2I2ZI26 A0A2I2ZI26 PAX9 PTHR45636:SF13 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-9 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000024094.2|UniProtKB=G3SD63 G3SD63 LOC101149535 PTHR24147:SF76 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 19-RELATED GORGO|Ensembl=ENSGGOG00000043135.1|UniProtKB=A0A2I2ZPT8 A0A2I2ZPT8 PTHR46232:SF5 SMARCE1 REGULATOR OF CHROMATIN HMG BOX DOMAIN-CONTAINING PROTEIN DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000041961.1|UniProtKB=A0A2I2YTU5 A0A2I2YTU5 PRKN PTHR11685:SF448 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE PARKIN protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;acyltransferase activity#GO:0016746;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;autophagy#GO:0006914;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;macroautophagy#GO:0016236;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;mitophagy#GO:0000423;ubiquitin-dependent protein catabolic process#GO:0006511 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Parkin#P01216 GORGO|Ensembl=ENSGGOG00000003941.3|UniProtKB=G3S997 G3S997 RNF185 PTHR12313:SF13 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF185 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000007346.3|UniProtKB=G3QWM8 G3QWM8 PTHR12874:SF9 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 48 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009752.3|UniProtKB=A0A2I2Z232 A0A2I2Z232 RXRA PTHR24083:SF39 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;nervous system development#GO:0007399;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;intracellular receptor signaling pathway#GO:0030522;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 Vitamin D metabolism and pathway#P04396>RXR#P04602 GORGO|Ensembl=ENSGGOG00000016028.3|UniProtKB=G3RIW8 G3RIW8 POLD4 PTHR14303:SF0 DNA POLYMERASE DELTA SUBUNIT 4 DNA POLYMERASE DELTA SUBUNIT 4 catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA-directed DNA polymerase activity#GO:0003887 nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;replisome#GO:0030894;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 GORGO|Ensembl=ENSGGOG00000008186.3|UniProtKB=G3QYR7 G3QYR7 PTHR11607:SF57 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2X hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 hydrolase#PC00121;glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000011151.3|UniProtKB=A0A2I2YIF0 A0A2I2YIF0 FTO PTHR31291:SF2 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO response to stress#GO:0006950;cellular process#GO:0009987;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016956.3|UniProtKB=G3RLA5 G3RLA5 CDH6 PTHR24027:SF322 CADHERIN-23 CADHERIN-6 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 anatomical structure morphogenesis#GO:0009653;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870;cell adhesion#GO:0007155;synapse organization#GO:0050808;synaptic membrane adhesion#GO:0099560;anatomical structure development#GO:0048856;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular component assembly#GO:0022607;cell migration#GO:0016477;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000013946.3|UniProtKB=G3RDK4 G3RDK4 CIAO3 PTHR11615:SF322 NITRATE, FORMATE, IRON DEHYDROGENASE CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 3 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000006021.3|UniProtKB=G3QT83 G3QT83 ICAM3 PTHR13771:SF17 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 3 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;leukocyte cell-cell adhesion#GO:0007159;cell adhesion#GO:0007155;cell adhesion mediated by integrin#GO:0033627 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000017197.3|UniProtKB=G3RLX0 G3RLX0 USP46 PTHR24006:SF714 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 46 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000008405.3|UniProtKB=G3RPJ5 G3RPJ5 GTF2H1 PTHR12856:SF0 TRANSCRIPTION INITIATION FACTOR IIH-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 1 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716 membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 GORGO|Ensembl=ENSGGOG00000013184.3|UniProtKB=G3RBL1 G3RBL1 LOC101136195 PTHR21553:SF22 ALMS1-RELATED CENTROSOME-ASSOCIATED PROTEIN ALMS1 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of organelle organization#GO:0033043;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of microtubule-based process#GO:0032886 cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000001976.3|UniProtKB=G3QHW2 G3QHW2 NCAPG2 PTHR16199:SF4 CONDENSIN-2 COMPLEX SUBUNIT G2 CONDENSIN-2 COMPLEX SUBUNIT G2 chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;nuclear division#GO:0000280;organelle fission#GO:0048285;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;condensin complex#GO:0000796;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006338.3|UniProtKB=G3QU07 G3QU07 C9orf72 PTHR31855:SF2 GUANINE NUCLEOTIDE EXCHANGE C9ORF72 GUANINE NUCLEOTIDE EXCHANGE FACTOR C9ORF72 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 transport#GO:0006810;regulation of response to stimulus#GO:0048583;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;import into cell#GO:0098657;establishment of localization#GO:0051234;regulation of TOR signaling#GO:0032006;regulation of metabolic process#GO:0019222;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;regulation of cell communication#GO:0010646;endocytosis#GO:0006897;regulation of cellular process#GO:0050794 endosome#GO:0005768;intracellular organelle#GO:0043229;autophagosome#GO:0005776;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000013382.3|UniProtKB=A0A2I2ZGZ1 A0A2I2ZGZ1 RRAGC PTHR11259:SF6 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN C GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;negative regulation of catabolic process#GO:0009895;positive regulation of TOR signaling#GO:0032008;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;positive regulation of TORC1 signaling#GO:1904263;response to nutrient levels#GO:0031667;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;response to stress#GO:0006950 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;lysosome#GO:0005764;nucleus#GO:0005634 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000004368.3|UniProtKB=G3QP02 G3QP02 RNF32 PTHR14991:SF0 RING FINGER PROTEIN 32 RING FINGER PROTEIN 32 GORGO|Ensembl=ENSGGOG00000004828.3|UniProtKB=G3QQ68 G3QQ68 LOC101132732 PTHR48018:SF137 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8D4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000024459.2|UniProtKB=G3SCM1 G3SCM1 LOC129532449 PTHR10871:SF54 30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN US13 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000022529.2|UniProtKB=G3S2R0 G3S2R0 CDYL PTHR43684:SF5 FAMILY NOT NAMED CHROMODOMAIN Y-LIKE PROTEIN protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;transcription regulator activity#GO:0140110;intramolecular oxidoreductase activity#GO:0016860;chromatin-protein adaptor activity#GO:0140463;isomerase activity#GO:0016853;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;catalytic activity#GO:0003824;transcription corepressor activity#GO:0003714;histone reader activity#GO:0140566;histone H3K9me2/3 reader activity#GO:0062072 lipid catabolic process#GO:0016042;cellular process#GO:0009987;metabolic process#GO:0008152;fatty acid oxidation#GO:0019395;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;spermatid differentiation#GO:0048515;monocarboxylic acid catabolic process#GO:0072329;male gamete generation#GO:0048232;carboxylic acid catabolic process#GO:0046395;lipid modification#GO:0030258;cellular developmental process#GO:0048869;fatty acid metabolic process#GO:0006631;developmental process#GO:0032502;spermatogenesis#GO:0007283;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;catabolic process#GO:0009056;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;germ cell development#GO:0007281;anatomical structure development#GO:0048856;lipid oxidation#GO:0034440;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;spermatid development#GO:0007286 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;microbody#GO:0042579;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000002377.3|UniProtKB=G3QIW9 G3QIW9 OGFOD1 PTHR12117:SF0 HISTONE ACETYLTRANSFERASE COMPLEX PROLYL 3-HYDROXYLASE OGFOD1 dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein-containing complex disassembly#GO:0043244;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000040355.1|UniProtKB=A0A2I2ZA34 A0A2I2ZA34 DUXB PTHR46123:SF5 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000000559.3|UniProtKB=G3QE63 G3QE63 MORN5 PTHR46437:SF1 MORN REPEAT-CONTAINING PROTEIN 5 MORN REPEAT-CONTAINING PROTEIN 5 GORGO|Ensembl=ENSGGOG00000009416.3|UniProtKB=G3R1X0 G3R1X0 LHPP PTHR19288:SF44 4-NITROPHENYLPHOSPHATASE-RELATED PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000012728.3|UniProtKB=G3RAE6 G3RAE6 ZDHHC14 PTHR22883:SF28 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC14 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000013220.3|UniProtKB=G3RBN5 G3RBN5 SNRNP48 PTHR21402:SF15 GAMETOCYTE SPECIFIC FACTOR 1-RELATED U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000040767.1|UniProtKB=A0A2I2ZEX6 A0A2I2ZEX6 LOC101139847 PTHR11581:SF35 30S/40S RIBOSOMAL PROTEIN S4 SMALL RIBOSOMAL SUBUNIT PROTEIN ES4, X ISOFORM structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013829.3|UniProtKB=G3RD92 G3RD92 IQCK PTHR34927:SF1 IQ DOMAIN-CONTAINING PROTEIN K IQ DOMAIN-CONTAINING PROTEIN K GORGO|Ensembl=ENSGGOG00000040800.1|UniProtKB=A0A2I2YMH3 A0A2I2YMH3 PTHR14768:SF5 UPF0338 PROTEIN TRANSMEMBRANE PROTEIN PMIS2 membrane#GO:0016020;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000014066.3|UniProtKB=G3RDV5 G3RDV5 LOC101141984 PTHR24253:SF193 TRANSMEMBRANE PROTEASE SERINE TRYPTASE catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000016073.3|UniProtKB=A0A2I2ZRC6 A0A2I2ZRC6 ABHD14B PTHR46197:SF2 PROTEIN ABHD14B-LIKE PROTEIN-LYSINE DEACYLASE ABHD14B-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011233.3|UniProtKB=G3RZP8 G3RZP8 SLC3A2 PTHR46673:SF1 4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN AMINO ACID TRANSPORTER HEAVY CHAIN SLC3A2 localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;import across plasma membrane#GO:0098739;L-leucine transport#GO:0015820;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;establishment of localization#GO:0051234;import into cell#GO:0098657;branched-chain amino acid transport#GO:0015803;alanine transport#GO:0032328;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;apical plasma membrane#GO:0016324;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical part of cell#GO:0045177 GORGO|Ensembl=ENSGGOG00000009847.3|UniProtKB=G3R2Y8 G3R2Y8 LOC101125304 PTHR23299:SF57 METALLOTHIONEIN METALLOTHIONEIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 cellular response to chemical stimulus#GO:0070887;inorganic ion homeostasis#GO:0098771;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;cellular response to stimulus#GO:0051716;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;response to cadmium ion#GO:0046686;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;response to metal ion#GO:0010038;response to chemical#GO:0042221;detoxification#GO:0098754;detoxification of inorganic compound#GO:0061687;monoatomic ion homeostasis#GO:0050801;response to stress#GO:0006950;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000037870.1|UniProtKB=A0A2I2YZV4 A0A2I2YZV4 ASTE1 PTHR15665:SF1 ASTEROID PROTEIN SINGLE-STRAND DNA ENDONUCLEASE ASTE1 GORGO|Ensembl=ENSGGOG00000023198.2|UniProtKB=G3S2A3 G3S2A3 BPIFA3 PTHR47736:SF1 BPI FOLD-CONTAINING FAMILY A MEMBER 3 BPI FOLD-CONTAINING FAMILY A MEMBER 3 GORGO|Ensembl=ENSGGOG00000012291.3|UniProtKB=A0A2I2ZLG0 A0A2I2ZLG0 TMEM231 PTHR14605:SF1 CHST5 PROTEIN TRANSMEMBRANE PROTEIN 231 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;regulation of localization#GO:0032879;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;cell projection organization#GO:0030030;organelle assembly#GO:0070925;cilium organization#GO:0044782;regulation of protein localization#GO:0032880 membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;cilium#GO:0005929;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 GORGO|Ensembl=ENSGGOG00000004113.3|UniProtKB=G3QNC3 G3QNC3 PLGRKT PTHR13411:SF7 PLASMINOGEN RECEPTOR (KT) PLASMINOGEN RECEPTOR (KT) regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of proteolysis#GO:0030162 GORGO|Ensembl=ENSGGOG00000008736.3|UniProtKB=G3SKB3 G3SKB3 ATP10D PTHR24092:SF84 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VD ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid transport#GO:0006869;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000036405.1|UniProtKB=A0A2I2ZXN9 A0A2I2ZXN9 PTHR15299:SF3 HERV-H LTR-ASSOCIATING PROTEIN 1 HERV-H LTR-ASSOCIATING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000007233.3|UniProtKB=G3S7Y3 G3S7Y3 ITCH PTHR11254:SF66 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE ITCHY HOMOLOG catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 GORGO|Ensembl=ENSGGOG00000040711.1|UniProtKB=A0A2I2Z0F5 A0A2I2Z0F5 MUC22 PTHR37000:SF3 MUCIN-22 MUCIN-22 GORGO|Ensembl=ENSGGOG00000001543.3|UniProtKB=G3RMU9 G3RMU9 SCNN1B PTHR11690:SF18 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED EPITHELIAL SODIUM CHANNEL SUBUNIT BETA metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014494.3|UniProtKB=G3REY3 G3REY3 SKA3 PTHR48118:SF2 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3 cell cycle#GO:0007049;chromosome segregation#GO:0007059;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;outer kinetochore#GO:0000940;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;spindle#GO:0005819;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000009893.4|UniProtKB=G3S0S4 G3S0S4 LOC101148343 PTHR11732:SF556 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER C4 alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 steroid metabolic process#GO:0008202;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000043646.1|UniProtKB=A0A2I2Z2S0 A0A2I2Z2S0 PTHR10826:SF1 COMPLEMENT COMPONENT 1 COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517 catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA catabolic process#GO:0006401 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 complement component#PC00078;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000012288.3|UniProtKB=A0A2I2Y8W2 A0A2I2Y8W2 CASP10 PTHR10454:SF240 CASPASE CASPASE-10 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 biological regulation#GO:0065007;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 Huntington disease#P00029>Caspase 8#P00808;FAS signaling pathway#P00020>Pro-Caspase10#P00598;Apoptosis signaling pathway#P00006>Caspase 10#P00295;Huntington disease#P00029>Pro-caspase 8#P00767;FAS signaling pathway#P00020>Caspase8#P00594;FAS signaling pathway#P00020>Pro-Caspase8#P00604;FAS signaling pathway#P00020>Caspase10#P00606;Apoptosis signaling pathway#P00006>Caspase 8#P00299 GORGO|Ensembl=ENSGGOG00000023751.2|UniProtKB=G3RYR2 G3RYR2 KBTBD8 PTHR24412:SF433 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 8 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001397.3|UniProtKB=A0A2I2YDQ0 A0A2I2YDQ0 AKT2 PTHR24351:SF192 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 response to peptide hormone#GO:0043434;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;response to hormone#GO:0009725;response to endogenous stimulus#GO:0009719 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002157.3|UniProtKB=G3S9M5 G3S9M5 OPRD1 PTHR24229:SF2 NEUROPEPTIDES RECEPTOR DELTA-TYPE OPIOID RECEPTOR signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;binding#GO:0005488;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Opioid proopiomelanocortin pathway#P05917>Mu or Delta receptor#P06004;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Enkephalin release#P05913>GPCR (i)#P05973;Opioid proenkephalin pathway#P05915>Mu or Delta receptor#P05985;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 GORGO|Ensembl=ENSGGOG00000000431.3|UniProtKB=G3QDU6 G3QDU6 CASP14 PTHR10454:SF131 CASPASE CASPASE-14 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175 regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;tissue development#GO:0009888;biological regulation#GO:0065007;epidermis development#GO:0008544;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;developmental process#GO:0032502;positive regulation of apoptotic process#GO:0043065;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000022049.2|UniProtKB=G3SE72 G3SE72 SAMD15 PTHR46829:SF1 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15 enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 GORGO|Ensembl=ENSGGOG00000000627.3|UniProtKB=G3QEC3 G3QEC3 P2RY4 PTHR24231:SF21 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 4 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000041158.1|UniProtKB=A0A2I2Y7A9 A0A2I2Y7A9 TACC3 PTHR13924:SF4 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 3 organelle localization#GO:0051640;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;supramolecular fiber organization#GO:0097435;cellular localization#GO:0051641;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cell cycle process#GO:0022402;nuclear migration#GO:0007097;cellular component organization#GO:0016043;cell cycle#GO:0007049;cytoplasmic microtubule organization#GO:0031122;establishment of organelle localization#GO:0051656;cell differentiation#GO:0030154;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501 microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;spindle pole#GO:0000922;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000006676.3|UniProtKB=G3QUX2 G3QUX2 SPP2 PTHR15444:SF4 SECRETED PHOSPHOPROTEIN 24 SECRETED PHOSPHOPROTEIN 24 GORGO|Ensembl=ENSGGOG00000003097.3|UniProtKB=A0A2I2Y685 A0A2I2Y685 SHMT1 PTHR11680:SF59 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;heterocyclic compound binding#GO:1901363;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283 nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 GORGO|Ensembl=ENSGGOG00000014456.3|UniProtKB=G3SD28 G3SD28 SURF4 PTHR23427:SF13 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 4 cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000041164.1|UniProtKB=A0A2I2YXS2 A0A2I2YXS2 LOC101150628 PTHR43625:SF11 AFLATOXIN B1 ALDEHYDE REDUCTASE AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 4-RELATED oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 metabolic process#GO:0008152;secondary metabolic process#GO:0019748;cellular process#GO:0009987;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;response to chemical#GO:0042221;catabolic process#GO:0009056;detoxification#GO:0098754 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000015116.3|UniProtKB=G3RGK2 G3RGK2 ZNF738 PTHR23232:SF67 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 738 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024791.2|UniProtKB=A0A2I2ZG35 A0A2I2ZG35 SMC2 PTHR43977:SF2 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN GORGO|Ensembl=ENSGGOG00000001181.3|UniProtKB=G3QFT5 G3QFT5 PWWP2A PTHR23068:SF4 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED PWWP DOMAIN-CONTAINING PROTEIN 2A binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA methyltransferase#PC00013 GORGO|Ensembl=ENSGGOG00000012355.3|UniProtKB=G3R9H1 G3R9H1 CIAO2B PTHR12377:SF0 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000040049.1|UniProtKB=A0A2I2YB11 A0A2I2YB11 FIGN PTHR23074:SF14 AAA DOMAIN-CONTAINING FIDGETIN ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000015421.3|UniProtKB=G3RHC9 G3RHC9 TWNK PTHR12873:SF7 T7-LIKE MITOCHONDRIAL DNA HELICASE TWINKLE MTDNA HELICASE macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;mitochondrial DNA metabolic process#GO:0032042;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA helicase#PC00011 GORGO|Ensembl=ENSGGOG00000009598.3|UniProtKB=G3R2C8 G3R2C8 CETN3 PTHR23048:SF68 MYOSIN LIGHT CHAIN 1, 3 CENTRIN 3-RELATED actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000012518.3|UniProtKB=G3R9W4 G3R9W4 WASF3 PTHR12902:SF7 WASP-1 ACTIN-BINDING PROTEIN WASF3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;protein kinase A regulatory subunit binding#GO:0034237;protein kinase A binding#GO:0051018;binding#GO:0005488 positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;positive regulation of organelle organization#GO:0010638;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956 cell leading edge#GO:0031252;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;lamellipodium#GO:0030027;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000041127.1|UniProtKB=A0A2I2ZF73 A0A2I2ZF73 PTHR18359:SF1 WD-REPEAT PROTEIN-RELATED UTP18 SMALL SUBUNIT PROCESSOME COMPONENT macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000009373.3|UniProtKB=G3RXN6 G3RXN6 ZNF592 PTHR47222:SF1 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 592 GORGO|Ensembl=ENSGGOG00000002318.3|UniProtKB=A0A2I2YVS2 A0A2I2YVS2 MFSD4A PTHR23121:SF10 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 1 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015838.3|UniProtKB=G3RIF3 G3RIF3 PTHR24043:SF5 SCAVENGER RECEPTOR CLASS F SCAVENGER RECEPTOR CLASS F MEMBER 2 cargo receptor activity#GO:0038024 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000042006.1|UniProtKB=A0A2I2YJN3 A0A2I2YJN3 PTHR19367:SF21 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-2 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000006485.3|UniProtKB=G3QUE5 G3QUE5 SPI1 PTHR11849:SF16 ETS TRANSCRIPTION FACTOR PU.1 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Interleukin signaling pathway#P00036>Ets#P00989 GORGO|Ensembl=ENSGGOG00000002015.3|UniProtKB=G3QI03 G3QI03 ZZEF1 PTHR22772:SF4 NOVEL ZZ TYPE ZINC FINGER DOMAIN CONTAINING PROTEIN ZINC FINGER ZZ-TYPE AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000015880.3|UniProtKB=G3S449 G3S449 APBB3 PTHR14058:SF10 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 3 binding#GO:0005488;peptide binding#GO:0042277 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 GORGO|Ensembl=ENSGGOG00000014675.3|UniProtKB=G3RFE9 G3RFE9 RHEB PTHR24070:SF264 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RHEB enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;protein kinase activator activity#GO:0030295;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 regulation of TORC1 signaling#GO:1903432;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;positive regulation of TORC1 signaling#GO:1904263;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 CCKR signaling map#P06959>RHEB-GTP#P07224;CCKR signaling map#P06959>RHEB-GDP#P07175;p53 pathway by glucose deprivation#P04397>Rheb#P04642 GORGO|Ensembl=ENSGGOG00000037368.1|UniProtKB=A0A2I2Z5M2 A0A2I2Z5M2 ZNF436 PTHR24381:SF434 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 436 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014988.3|UniProtKB=G3RG92 G3RG92 WWP1 PTHR11254:SF299 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP1 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 GORGO|Ensembl=ENSGGOG00000002260.3|UniProtKB=G3QIL4 G3QIL4 IPO7 PTHR10997:SF27 IMPORTIN-7, 8, 11 IMPORTIN-7 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641 nucleus#GO:0005634;organelle envelope#GO:0031967;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000022268.2|UniProtKB=A0A2I2Z9J4 A0A2I2Z9J4 PPIL3 PTHR45625:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000025219.2|UniProtKB=G3S0T2 G3S0T2 PTHR31905:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 PROTEIN MIX23 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000022797.2|UniProtKB=G3SDY6 G3SDY6 LOC101138286 PTHR48026:SF9 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN RRM DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000003650.3|UniProtKB=G3QM58 G3QM58 ZNF189 PTHR24377:SF316 IP01015P-RELATED ZINC FINGER PROTEIN 189 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000000250.3|UniProtKB=G3SHZ7 G3SHZ7 RAB31 PTHR24073:SF588 DRAB5-RELATED RAS-RELATED PROTEIN RAB-31 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 intracellular organelle#GO:0043229;endosome#GO:0005768;organelle subcompartment#GO:0031984;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;late endosome#GO:0005770;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000006509.3|UniProtKB=G3QUG4 G3QUG4 ASB4 PTHR46224:SF6 ANKYRIN REPEAT FAMILY PROTEIN IQ MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000009826.3|UniProtKB=A0A2I2Y9Z1 A0A2I2Y9Z1 PTHR13794:SF58 ENOLASE SUPERFAMILY, MANDELATE RACEMASE MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 epimerase/racemase#PC00096 GORGO|Ensembl=ENSGGOG00000012318.3|UniProtKB=G3R9D6 G3R9D6 GDF9 PTHR11848:SF19 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 9 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000012637.3|UniProtKB=G3RA71 G3RA71 TARBP2 PTHR46205:SF1 LOQUACIOUS, ISOFORM B RISC-LOADING COMPLEX SUBUNIT TARBP2 RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of biological process#GO:0050789;siRNA processing#GO:0030422;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000015060.3|UniProtKB=A0A2I2Z6I6 A0A2I2Z6I6 CFAP70 PTHR44314:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium movement#GO:0003341;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000009621.3|UniProtKB=G3RZ41 G3RZ41 ALKBH2 PTHR31573:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2 DNA OXIDATIVE DEMETHYLASE ALKBH2 transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;dioxygenase activity#GO:0051213;hydrolase activity#GO:0016787;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;binding#GO:0005488;metal ion binding#GO:0046872;ferrous iron binding#GO:0008198;demethylase activity#GO:0032451;iron ion binding#GO:0005506;catalytic activity, acting on DNA#GO:0140097 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000040916.1|UniProtKB=G3SAA3 G3SAA3 LOC101124941 PTHR24255:SF27 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED HAPTOGLOBIN-RELATED PROTEIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;zymogen activation#GO:0031638;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000003969.3|UniProtKB=G3QMZ5 G3QMZ5 TMCC1 PTHR17613:SF11 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAINS PROTEIN 1 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;endosome organization#GO:0007032;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;membrane fission#GO:0090148;cellular localization#GO:0051641;organelle fission#GO:0048285;localization#GO:0051179 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040207.1|UniProtKB=A0A2I2ZTU1 A0A2I2ZTU1 PTHR11849:SF281 ETS TRANSCRIPTION FACTOR SPI-C DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000015739.3|UniProtKB=G3RI65 G3RI65 HOMER2 PTHR10918:SF2 HOMER HOMER PROTEIN HOMOLOG 2 G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;multicellular organismal process#GO:0032501;regulation of monoatomic ion transport#GO:0043269;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of transport#GO:0051049;system process#GO:0003008;regulation of localization#GO:0032879;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of sound#GO:0007605;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cell junction#GO:0030054;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000011383.3|UniProtKB=G3R6X6 G3R6X6 LSM2 PTHR13829:SF2 SNRNP CORE PROTEIN FAMILY MEMBER U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000041034.1|UniProtKB=A0A2I2Z6M2 A0A2I2Z6M2 LOC101136183 PTHR26452:SF769 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5F1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000012357.3|UniProtKB=G3R9H5 G3R9H5 IQCF2 PTHR21633:SF4 IQ MOTIF CONTAINING F IQ DOMAIN-CONTAINING PROTEIN F2 GORGO|Ensembl=ENSGGOG00000023227.2|UniProtKB=G3SDT1 G3SDT1 PTHR23226:SF412 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007178.3|UniProtKB=G3QW76 G3QW76 SERPINE1 PTHR11461:SF49 SERINE PROTEASE INHIBITOR, SERPIN PLASMINOGEN ACTIVATOR INHIBITOR 1 serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 negative regulation of coagulation#GO:0050819;regulation of biological quality#GO:0065008;positive regulation of coagulation#GO:0050820;negative regulation of hemostasis#GO:1900047;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;negative regulation of metabolic process#GO:0009892;regulation of wound healing#GO:0061041;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of response to wounding#GO:1903035;regulation of proteolysis#GO:0030162;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of response to wounding#GO:1903034;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;regulation of angiogenesis#GO:0045765;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;negative regulation of protein metabolic process#GO:0051248;negative regulation of multicellular organismal process#GO:0051241;regulation of biosynthetic process#GO:0009889;negative regulation of angiogenesis#GO:0016525;regulation of gene expression#GO:0010468;regulation of vasculature development#GO:1901342;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;negative regulation of blood coagulation#GO:0030195;regulation of response to stimulus#GO:0048583;regulation of coagulation#GO:0050818;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of wound healing#GO:0061045;negative regulation of macromolecule metabolic process#GO:0010605;regulation of hemostasis#GO:1900046 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Blood coagulation#P00011>PAI-1#P00411;p53 pathway#P00059>PAI#G04700;Plasminogen activating cascade#P00050>PAI-1#P01245;CCKR signaling map#P06959>PAI1#G07281;CCKR signaling map#P06959>PAI1#G06987 GORGO|Ensembl=ENSGGOG00000026413.2|UniProtKB=G3SBL4 G3SBL4 LOC134759281 PTHR11442:SF94 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT GAMMA-1 heme binding#GO:0020037;binding#GO:0005488;molecular carrier activity#GO:0140104;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515 cell development#GO:0048468;homeostatic process#GO:0042592;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;localization#GO:0051179;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;cellular process#GO:0009987;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 globin#PC00107;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000011629.3|UniProtKB=G3R7K1 G3R7K1 RARRES1 PTHR28591:SF2 LATEXIN RETINOIC ACID RECEPTOR RESPONDER PROTEIN 1 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000005763.3|UniProtKB=G3QSK9 G3QSK9 CPNE5 PTHR10857:SF51 COPINE COPINE-5 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 response to metal ion#GO:0010038;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;response to calcium ion#GO:0051592;response to stimulus#GO:0050896;response to chemical#GO:0042221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000015492.3|UniProtKB=G3RHJ8 G3RHJ8 PTHR22891:SF41 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 3 nuclease activity#GO:0004518;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;multicellular organismal reproductive process#GO:0048609;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;male gamete generation#GO:0048232;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;spermatogenesis#GO:0007283;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;intracellular organelle#GO:0043229 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000003820.3|UniProtKB=G3QML2 G3QML2 PHACTR1 PTHR12751:SF6 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 1 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;stress fiber assembly#GO:0043149;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;contractile actin filament bundle assembly#GO:0030038;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000002527.3|UniProtKB=G3QJA0 G3QJA0 LOC101142804 PTHR13718:SF117 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016092.3|UniProtKB=G3S041 G3S041 DDX43 PTHR47958:SF212 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX43-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000024846.2|UniProtKB=A0A2I2YMX5 A0A2I2YMX5 PTHR23087:SF23 NONHISTONE CHROMOSOMAL PROTEIN HMG HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 3 chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000040215.1|UniProtKB=A0A2I2ZUC0 A0A2I2ZUC0 FABP5 PTHR11955:SF58 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 5 organic acid binding#GO:0043177;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;fatty acid binding#GO:0005504 lipid localization#GO:0010876;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;lipid transport#GO:0006869 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000037852.1|UniProtKB=A0A2I2YK52 A0A2I2YK52 PTHR10804:SF132 PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P PEPTIDASE M24 DOMAIN-CONTAINING PROTEIN protease#PC00190 GORGO|Ensembl=ENSGGOG00000001736.3|UniProtKB=G3QH86 G3QH86 SLC35B4 PTHR10778:SF4 SOLUTE CARRIER FAMILY 35 MEMBER B NUCLEOTIDE SUGAR TRANSPORTER SLC35B4 nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;nucleotide-sugar transmembrane transport#GO:0015780;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748 endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000001813.3|UniProtKB=G3QHF8 G3QHF8 SNAPIN PTHR31305:SF3 SNARE-ASSOCIATED PROTEIN SNAPIN SNARE-ASSOCIATED PROTEIN SNAPIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;regulation of intracellular pH#GO:0051453;organelle localization#GO:0051640;regulation of pH#GO:0006885;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;homeostatic process#GO:0042592;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;vesicle localization#GO:0051648;regulation of biological quality#GO:0065008;secretion by cell#GO:0032940;cellular localization#GO:0051641;lysosomal transport#GO:0007041;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;exocytosis#GO:0006887;endosomal transport#GO:0016197;vesicle-mediated transport in synapse#GO:0099003;chemical homeostasis#GO:0048878;regulated exocytosis#GO:0045055;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;synaptic vesicle transport#GO:0048489;synaptic signaling#GO:0099536;monoatomic ion homeostasis#GO:0050801 intracellular protein-containing complex#GO:0140535;cell junction#GO:0030054;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle#GO:0030133;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;BLOC-1 complex#GO:0031083;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708 GORGO|Ensembl=ENSGGOG00000003888.3|UniProtKB=G3QMS3 G3QMS3 ATP6V1B2 PTHR43389:SF5 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, BRAIN ISOFORM homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;apical plasma membrane#GO:0016324;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex#GO:0016469;apical part of cell#GO:0045177;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886 ATP synthase#PC00002;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000003251.3|UniProtKB=G3QL51 G3QL51 CARD6 PTHR22797:SF36 CARD6/NUCLEOLAR PROTEIN 3 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 6 GORGO|Ensembl=ENSGGOG00000001700.3|UniProtKB=G3RRU6 G3RRU6 FAM216A PTHR16476:SF1 FAMILY WITH SEQUENCE SIMILARITY 216 MEMBER A PROTEIN FAM216A GORGO|Ensembl=ENSGGOG00000042345.1|UniProtKB=G3R0N1 G3R0N1 ZIC4 PTHR19818:SF167 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 4 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014071.3|UniProtKB=G3RDV9 G3RDV9 PAAF1 PTHR22847:SF653 WD40 REPEAT PROTEIN PROTEASOMAL ATPASE-ASSOCIATED FACTOR 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000008097.3|UniProtKB=G3QYI2 G3QYI2 PTHR24102:SF18 PHD FINGER PROTEIN PHD FINGER PROTEIN 21B GORGO|Ensembl=ENSGGOG00000008854.3|UniProtKB=G3RV80 G3RV80 FGF3 PTHR11486:SF26 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 3 receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;developmental process#GO:0032502;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000007102.3|UniProtKB=G3QW10 G3QW10 STARD3 PTHR46121:SF2 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STAR-RELATED LIPID TRANSFER PROTEIN 3 alcohol binding#GO:0043178;cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496;small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934 lipid localization#GO:0010876;transport#GO:0006810;localization#GO:0051179;sterol transport#GO:0015918;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;lipid transport#GO:0006869 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane contact site#GO:0044232;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000017028.3|UniProtKB=G3RLH9 G3RLH9 PTHR24023:SF866 COLLAGEN ALPHA COLLAGEN ALPHA-3(IX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;basement membrane#GO:0005604;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000010014.3|UniProtKB=G3R3F0 G3R3F0 FCAMR PTHR11860:SF49 POLYMERIC-IMMUNOGLOBULIN RECEPTOR HIGH AFFINITY IMMUNOGLOBULIN ALPHA AND IMMUNOGLOBULIN MU FC RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000002777.3|UniProtKB=G3QJX6 G3QJX6 CCN3 PTHR11348:SF8 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 3 cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;signaling receptor binding#GO:0005102;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 system development#GO:0048731;cartilage development#GO:0051216;skeletal system development#GO:0001501;cell communication#GO:0007154;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of developmental process#GO:0050793;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;connective tissue development#GO:0061448;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;biological regulation#GO:0065007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;chondrocyte differentiation#GO:0002062;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 GORGO|Ensembl=ENSGGOG00000013925.3|UniProtKB=G3RDH7 G3RDH7 LOC101154188 PTHR12471:SF3 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1-LIKE PROTEIN biological regulation#GO:0065007;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080 ATPase dependent transmembrane transport complex#GO:0098533;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane#GO:0016020;membrane protein complex#GO:0098796 primary active transporter#PC00068;ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000001746.3|UniProtKB=G3QH92 G3QH92 LOC101152675 PTHR24147:SF1 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 20A1-RELATED GORGO|Ensembl=ENSGGOG00000000801.3|UniProtKB=G3S101 G3S101 LYPD6B PTHR31171:SF3 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6 LY6_PLAUR DOMAIN-CONTAINING PROTEIN 6B acetylcholine receptor regulator activity#GO:0030548;signaling receptor regulator activity#GO:0030545;neurotransmitter receptor regulator activity#GO:0099602;molecular function regulator activity#GO:0098772 GORGO|Ensembl=ENSGGOG00000013790.3|UniProtKB=G3RD57 G3RD57 ZCCHC9 PTHR46242:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC9 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013010.3|UniProtKB=G3R714 G3R714 ING1 PTHR10333:SF85 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 1 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000023955.2|UniProtKB=G3RRL6 G3RRL6 NUDT12 PTHR42904:SF6 NUDIX HYDROLASE, NUDC SUBFAMILY NAD-CAPPED RNA HYDROLASE NUDT12 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;pyridine nucleotide catabolic process#GO:0019364;nucleoside phosphate metabolic process#GO:0006753;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000010347.3|UniProtKB=G3R4A7 G3R4A7 SLC39A6 PTHR12191:SF22 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP6 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;zinc ion transmembrane transporter activity#GO:0005385;bicarbonate transmembrane transporter activity#GO:0015106;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293 inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000005881.3|UniProtKB=G3QSW5 G3QSW5 PTHR44899:SF1 CAMK FAMILY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NEK5 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000039658.1|UniProtKB=A0A2I2ZMF1 A0A2I2ZMF1 PTHR10015:SF140 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK TRANSCRIPTION FACTOR, X-LINKED MEMBER 3-RELATED helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000010557.3|UniProtKB=G3SE17 G3SE17 LOC101136522 PTHR23262:SF206 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-1-RELATED structural protein#PC00211 GORGO|Gene=TAS2R3|UniProtKB=Q645Y5 Q645Y5 TAS2R3 PTHR11394:SF49 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 3 transmembrane signaling receptor activity#GO:0004888;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527 multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001890.3|UniProtKB=G3QHM9 G3QHM9 CIMIP2A PTHR47299:SF1 PROTEIN FAM166A CILIARY MICROTUBULE INNER PROTEIN 2A GORGO|Ensembl=ENSGGOG00000002056.3|UniProtKB=G3QI28 G3QI28 APEX2 PTHR22748:SF4 AP ENDONUCLEASE DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2 exonuclease activity#GO:0004527;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity#GO:0004529;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;phosphoric ester hydrolase activity#GO:0042578;3'-5' exonuclease activity#GO:0008408;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;endonuclease activity#GO:0004519 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002269.3|UniProtKB=G3QIM1 G3QIM1 ARHGAP29 PTHR15228:SF7 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 29 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000040172.1|UniProtKB=A0A2I2Y5S4 A0A2I2Y5S4 PNMA8C PTHR23095:SF43 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 8C transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000003213.3|UniProtKB=G3QL19 G3QL19 EYA1 PTHR10190:SF11 EYES ABSENT PROTEIN PHOSPHATASE EYA1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 anatomical structure development#GO:0048856;embryonic organ development#GO:0048568;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;positive regulation of DNA metabolic process#GO:0051054;cellular developmental process#GO:0048869;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of response to stress#GO:0080134;sensory organ development#GO:0007423;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;inner ear development#GO:0048839;regulation of primary metabolic process#GO:0080090;ear development#GO:0043583;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;sensory organ morphogenesis#GO:0090596;cell differentiation#GO:0030154;regulation of DNA metabolic process#GO:0051052;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;inner ear morphogenesis#GO:0042472 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000024104.2|UniProtKB=A0A2I2YHG3 A0A2I2YHG3 PTHR13344:SF0 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000011433.3|UniProtKB=G3RJR1 G3RJR1 PTHR32157:SF8 GENE 6268-RELATED CANCER_TESTIS ANTIGEN 47A GORGO|Ensembl=ENSGGOG00000023038.2|UniProtKB=A0A2I2YSW6 A0A2I2YSW6 PTHR35088:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 178 COILED-COIL DOMAIN-CONTAINING PROTEIN 178 GORGO|Ensembl=ENSGGOG00000011527.3|UniProtKB=G3R7B4 G3R7B4 NAA35 PTHR21373:SF1 GLUCOSE REPRESSIBLE PROTEIN MAK10 N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000015376.3|UniProtKB=A0A2I2ZI55 A0A2I2ZI55 CYTH3 PTHR10663:SF320 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-3 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000014760.3|UniProtKB=G3RFN3 G3RFN3 TLE6 PTHR10814:SF2 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 6 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of canonical Wnt signaling pathway#GO:0060828 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 GORGO|Gene=TAS2R42|UniProtKB=Q645Z3 Q645Z3 TAS2R42 PTHR11394:SF70 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 42 transmembrane signaling receptor activity#GO:0004888;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001955.3|UniProtKB=G3QWE7 G3QWE7 PTHR23226:SF313 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 93 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000000993.3|UniProtKB=G3QFB2 G3QFB2 FAM222A PTHR16070:SF2 PROTEIN FAM222A-RELATED PROTEIN FAM222A GORGO|Ensembl=ENSGGOG00000004656.3|UniProtKB=G3QPR0 G3QPR0 ERF PTHR11849:SF31 ETS ETS DOMAIN-CONTAINING TRANSCRIPTION FACTOR ERF transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000005260.3|UniProtKB=G3QRA4 G3QRA4 CD2 PTHR12080:SF54 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE T-CELL SURFACE ANTIGEN CD2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;immune system process#GO:0002376;cell activation#GO:0001775;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;leukocyte activation#GO:0045321;T cell activation#GO:0042110;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000006807.3|UniProtKB=G3QVA1 G3QVA1 IFT57 PTHR16011:SF0 IFT57/HIPPI INTRAFLAGELLAR TRANSPORT PROTEIN 57 HOMOLOG cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;Golgi apparatus#GO:0005794;intraciliary transport particle B#GO:0030992;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 structural protein#PC00211 Huntington disease#P00029>Hip-12#P00763;Huntington disease#P00029>Hippi#P00794 GORGO|Ensembl=ENSGGOG00000038962.1|UniProtKB=A0A2I2ZTH6 A0A2I2ZTH6 PTHR23268:SF6 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 5-5-RELATED regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000003688.3|UniProtKB=G3SFA2 G3SFA2 OXA1L PTHR12428:SF66 OXA1 MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;protein insertion into membrane#GO:0051205;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365 organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011831.3|UniProtKB=G3R847 G3R847 MYLK2 PTHR24347:SF373 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE 2, SKELETAL_CARDIAC MUSCLE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;myosin binding#GO:0017022;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;cytoskeletal protein binding#GO:0008092 muscle tissue development#GO:0060537;system development#GO:0048731;tissue morphogenesis#GO:0048729;cell communication#GO:0007154;anatomical structure development#GO:0048856;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;animal organ morphogenesis#GO:0009887;heart morphogenesis#GO:0003007;cellular response to stimulus#GO:0051716;system process#GO:0003008;cardiac muscle tissue development#GO:0048738;muscle contraction#GO:0006936;developmental process#GO:0032502;biological regulation#GO:0065007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;multicellular organism development#GO:0007275;animal organ development#GO:0048513;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;heart development#GO:0007507;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 GORGO|Ensembl=ENSGGOG00000023878.2|UniProtKB=G3S7Y6 G3S7Y6 CCDC102A PTHR46292:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 102A COILED-COIL DOMAIN-CONTAINING PROTEIN 102A GORGO|Ensembl=ENSGGOG00000012073.3|UniProtKB=G3R8Q8 G3R8Q8 DMBX1 PTHR46639:SF2 DIENCEPHALON/MESENCEPHALON HOMEOBOX PROTEIN 1 DIENCEPHALON_MESENCEPHALON HOMEOBOX PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000009676.3|UniProtKB=G3R2J8 G3R2J8 PRR7 PTHR16209:SF3 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 PROLINE-RICH PROTEIN 7 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 membraneless organelle#GO:0043228;cell junction#GO:0030054;nucleus#GO:0005634;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;intracellular membraneless organelle#GO:0043232;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000043069.1|UniProtKB=A0A2I2Z054 A0A2I2Z054 NOXRED1 PTHR11645:SF58 PYRROLINE-5-CARBOXYLATE REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038 metabolite interconversion enzyme#PC00262;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000006434.3|UniProtKB=A0A2I2ZT62 A0A2I2ZT62 VWDE PTHR14949:SF53 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 VON WILLEBRAND FACTOR D AND EGF DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000000777.3|UniProtKB=G3RTA2 G3RTA2 CMTM7 PTHR22776:SF89 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 7 signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;toll-like receptor signaling pathway#GO:0002224;immune system process#GO:0002376;regulation of response to external stimulus#GO:0032101;lymphocyte activation#GO:0046649;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;B cell activation#GO:0042113;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;innate immune response-activating signaling pathway#GO:0002758;cell communication#GO:0007154;regulation of defense response#GO:0031347;cell activation#GO:0001775;regulation of immune response#GO:0050776;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;activation of innate immune response#GO:0002218;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039422.1|UniProtKB=G3RUW7 G3RUW7 NHERF4 PTHR14191:SF20 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF4 signaling receptor binding#GO:0005102;binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515 protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular process#GO:0009987 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000042760.1|UniProtKB=A0A2I2ZHN2 A0A2I2ZHN2 CDRT4 PTHR37885:SF1 CMT1A DUPLICATED REGION TRANSCRIPT 4 PROTEIN CMT1A DUPLICATED REGION TRANSCRIPT 4 PROTEIN GORGO|Ensembl=ENSGGOG00000036768.1|UniProtKB=A0A2I2ZDA7 A0A2I2ZDA7 DDX19B PTHR47958:SF208 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX19B isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;nuclear transport#GO:0051169;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000002439.3|UniProtKB=G3QJ22 G3QJ22 DDX4 PTHR47958:SF205 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX4-RELATED helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657 anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;developmental process#GO:0032502;cell differentiation#GO:0030154;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;cellular process#GO:0009987;germ cell development#GO:0007281 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000028005.2|UniProtKB=G3SIN8 G3SIN8 LRRC30 PTHR48051:SF77 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 30A intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000022265.2|UniProtKB=G3S075 G3S075 PTHR11375:SF20 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Gene=MT-ATP8|UniProtKB=Q34571 Q34571 MT-ATP8 PTHR13722:SF0 ATP SYNTHASE PROTEIN 8 ATP SYNTHASE F(0) COMPLEX SUBUNIT 8 proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267 nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000005396.3|UniProtKB=G3QRM1 G3QRM1 PTHR28607:SF3 EXPRESSED PROTEIN MEMBRANE PROTEIN FAM174B GORGO|Ensembl=ENSGGOG00000012523.3|UniProtKB=G3RA04 G3RA04 COL4A1 PTHR24023:SF854 COLLAGEN ALPHA COLLAGEN ALPHA-1(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000042235.1|UniProtKB=A0A2I2Z3P0 A0A2I2Z3P0 PTHR37553:SF8 DUF4705 DOMAIN-CONTAINING PROTEIN DUF4705 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000005827.3|UniProtKB=G3QSR0 G3QSR0 BIRC3 PTHR10044:SF178 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 3 catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;enzyme regulator activity#GO:0030234;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of protein modification process#GO:0031399;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of protein ubiquitination#GO:0031396;negative regulation of apoptotic process#GO:0043066;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 Apoptosis signaling pathway#P00006>c-IAP1,2#P00264;CCKR signaling map#P06959>BIRC3#G07286 GORGO|Ensembl=ENSGGOG00000008555.3|UniProtKB=G3QZQ1 G3QZQ1 ARFGAP2 PTHR45686:SF10 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Gene=MT-ND1|UniProtKB=Q9T9Z0 Q9T9Z0 MT-ND1 PTHR11432:SF23 NADH DEHYDROGENASE SUBUNIT 1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 1 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000025941.2|UniProtKB=A0A2I2ZY43 A0A2I2ZY43 PTHR21713:SF29 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NAC-A_B DOMAIN-CONTAINING PROTEIN localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000003210.3|UniProtKB=G3QL14 G3QL14 BHMT2 PTHR46120:SF3 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 S-METHYLMETHIONINE--HOMOCYSTEINE S-METHYLTRANSFERASE BHMT2 transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000002032.3|UniProtKB=G3QI09 G3QI09 UHMK1 PTHR46962:SF1 SERINE/THREONINE-PROTEIN KINASE KIST SERINE_THREONINE-PROTEIN KINASE KIST transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672 regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of translational initiation#GO:0006446;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of translation#GO:0045727;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201 membraneless organelle#GO:0043228;nucleus#GO:0005634;neuron projection#GO:0043005;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;neuron projection cytoplasm#GO:0120111;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000014872.3|UniProtKB=A0A2I2Z5G9 A0A2I2Z5G9 MISP PTHR18839:SF3 MITOTIC INTERACTOR AND SUBSTRATE OF PLK1 MISP FAMILY MEMBER MITOTIC INTERACTOR AND SUBSTRATE OF PLK1 GORGO|Ensembl=ENSGGOG00000016541.3|UniProtKB=G3RK88 G3RK88 ACTN1 PTHR11915:SF434 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-1 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;muscle cell development#GO:0055001;cellular component organization#GO:0016043;muscle cell differentiation#GO:0042692;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856 intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoskeleton#GO:0005856;stress fiber#GO:0001725;I band#GO:0031674;cell junction#GO:0030054;sarcomere#GO:0030017;membraneless organelle#GO:0043228;membrane#GO:0016020;contractile muscle fiber#GO:0043292;actomyosin#GO:0042641;cell periphery#GO:0071944;Z disc#GO:0030018;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 GORGO|Gene=CTTNBP2|UniProtKB=Q2IBF7 Q2IBF7 CTTNBP2 PTHR24166:SF27 ROLLING PEBBLES, ISOFORM B CORTACTIN-BINDING PROTEIN 2 regulation of biological process#GO:0050789;regulation of synapse organization#GO:0050807;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of synapse structure or activity#GO:0050803 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016709.3|UniProtKB=G3RKM5 G3RKM5 DGCR6 PTHR13054:SF2 DIGEORGE SYNDROME CRITICAL REGION 6 DGCR6 FAMILY MEMBER PROTEIN DGCR6 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007519.3|UniProtKB=G3QX27 G3QX27 ZBTB8OS PTHR12682:SF12 ARCHEASE TRNA-SPLICING LIGASE-ACTIVATING FACTOR ARCHEASE catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000006321.3|UniProtKB=G3QTZ3 G3QTZ3 MBIP PTHR23404:SF3 MOLYBDOPTERIN SYNTHASE RELATED MAP3K12-BINDING INHIBITORY PROTEIN 1 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000014670.3|UniProtKB=A0A2I2YU09 A0A2I2YU09 XG PTHR15076:SF4 CD99/MIC2 PROTEIN RELATED GLYCOPROTEIN XG mononuclear cell migration#GO:0071674;immune system process#GO:0002376;cell adhesion#GO:0007155;regulation of cell motility#GO:2000145;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of immune system process#GO:0002682;regulation of leukocyte migration#GO:0002685;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;positive regulation of immune system process#GO:0002684;lymphocyte migration#GO:0072676;cell-cell adhesion#GO:0098609;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell migration#GO:0016477;homotypic cell-cell adhesion#GO:0034109;regulation of locomotion#GO:0040012;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000034860.2|UniProtKB=G3SKI2 G3SKI2 CFAP69 PTHR14716:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 regulation of microtubule-based process#GO:0032886;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of cell motility#GO:2000147;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;regulation of reproductive process#GO:2000241;response to stimulus#GO:0050896;regulation of microtubule-based movement#GO:0060632;response to chemical#GO:0042221 9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000039378.1|UniProtKB=A0A2I2ZGM6 A0A2I2ZGM6 PTHR14136:SF30 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 KHA DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000002161.3|UniProtKB=G3QIC3 G3QIC3 RPS3A PTHR11830:SF22 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000015436.3|UniProtKB=G3RRE3 G3RRE3 PDZD7 PTHR23116:SF29 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED PDZ DOMAIN-CONTAINING PROTEIN 7 cellular component organization#GO:0016043;inner ear receptor cell stereocilium organization#GO:0060122;anatomical structure morphogenesis#GO:0009653;sensory organ morphogenesis#GO:0090596;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;sensory perception of sound#GO:0007605;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;nervous system process#GO:0050877;generation of neurons#GO:0048699;neuron development#GO:0048666;ear development#GO:0043583;hair cell differentiation#GO:0035315;inner ear morphogenesis#GO:0042472;neuron projection development#GO:0031175;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;embryo development#GO:0009790;neuron differentiation#GO:0030182;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ morphogenesis#GO:0009887;embryonic organ development#GO:0048568;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;anatomical structure development#GO:0048856;system development#GO:0048731;inner ear development#GO:0048839;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelium development#GO:0060429;plasma membrane bounded cell projection organization#GO:0120036;epidermis development#GO:0008544;sensory organ development#GO:0007423;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;system process#GO:0003008 intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;stereocilium#GO:0032420;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000016845.3|UniProtKB=G3RTP6 G3RTP6 KCNH6 PTHR10217:SF468 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED INWARDLY RECTIFYING POTASSIUM CHANNEL KCNH6 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;metal ion transport#GO:0030001;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000039326.1|UniProtKB=A0A2I2YLG6 A0A2I2YLG6 S1PR3 PTHR22750:SF24 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 3 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007808.3|UniProtKB=G3QXU1 G3QXU1 PLCG1 PTHR10336:SF173 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-1 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;lipase activity#GO:0016298 calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;metabolic process#GO:0008152;glycerophospholipid metabolic process#GO:0006650;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;positive regulation of cell motility#GO:2000147;calcium ion transmembrane transport#GO:0070588;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;positive regulation of locomotion#GO:0040017;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;transport#GO:0006810;regulation of cell migration#GO:0030334;monoatomic ion transmembrane transport#GO:0034220;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of cell motility#GO:2000145;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;ruffle#GO:0001726 phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;PDGF signaling pathway#P00047>PLCgamma#P01171;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;EGF receptor signaling pathway#P00018>PLCgamma#P00556;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;FGF signaling pathway#P00021>PLCgamma#P00638;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Angiogenesis#P00005>PLC-gamma#P00256;CCKR signaling map#P06959>PLCgamma1#P07037;T cell activation#P00053>PLC-gamma#P01320;VEGF signaling pathway#P00056>PLC-gamma#P01414 GORGO|Ensembl=ENSGGOG00000012319.3|UniProtKB=G3R9D7 G3R9D7 SOX4 PTHR10270:SF27 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-4 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 camera-type eye development#GO:0043010;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;camera-type eye morphogenesis#GO:0048593;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;sensory organ morphogenesis#GO:0090596;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;sensory system development#GO:0048880;negative regulation of macromolecule biosynthetic process#GO:0010558;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000034995.2|UniProtKB=G3SKT0 G3SKT0 STK31 PTHR43289:SF6 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE_THREONINE KINASE 31 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000013241.3|UniProtKB=G3RBR0 G3RBR0 BBS1 PTHR20870:SF0 BARDET-BIEDL SYNDROME 1 PROTEIN BBSOME COMPLEX MEMBER BBS1 signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 organelle assembly#GO:0070925;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;localization#GO:0051179;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;BBSome#GO:0034464;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000038964.1|UniProtKB=A0A2I2YMC9 A0A2I2YMC9 PTHR14063:SF1 PROTEIN LIN-7 HOMOLOG PDZ DOMAIN-CONTAINING PROTEIN 11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 transport#GO:0006810;establishment of localization#GO:0051234;vesicle localization#GO:0051648;regulation of synapse assembly#GO:0051963;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;signal release#GO:0023061;regulation of cell junction assembly#GO:1901888;secretion#GO:0046903;regulation of synapse structure or activity#GO:0050803;localization#GO:0051179;cell communication#GO:0007154;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of growth#GO:0040008;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of developmental process#GO:0050793;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;synaptic vesicle transport#GO:0048489;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle localization#GO:0097479;cellular component assembly#GO:0022607;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;regulation of synapse organization#GO:0050807;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;secretion by cell#GO:0032940;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;export from cell#GO:0140352;signaling#GO:0023052 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell-cell junction#GO:0005911;membrane#GO:0016020 cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000025153.2|UniProtKB=G3SJV2 G3SJV2 SEMA4G PTHR11036:SF17 SEMAPHORIN SEMAPHORIN-4G signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;axon guidance#GO:0007411;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;chemotaxis#GO:0006935;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000001004.3|UniProtKB=G3QFC2 G3QFC2 CAND2 PTHR12696:SF2 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 2 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein-containing complex assembly#GO:0065003;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein modification process#GO:0036211;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000036307.1|UniProtKB=G3QQW9 G3QQW9 UBE2T PTHR24068:SF159 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 T catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA damage response#GO:0006974;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000010904.3|UniProtKB=G3R5P4 G3R5P4 MAGEA1 PTHR11736:SF49 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 1 enzyme binding#GO:0019899;binding#GO:0005488;histone deacetylase binding#GO:0042826;protein binding#GO:0005515 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000034813.2|UniProtKB=G3SKL7 G3SKL7 NOTUM PTHR21562:SF7 NOTUM-RELATED PALMITOLEOYL-PROTEIN CARBOXYLESTERASE NOTUM GORGO|Ensembl=ENSGGOG00000010908.3|UniProtKB=A0A2I2YBS2 A0A2I2YBS2 GABRG2 PTHR18945:SF498 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;nervous system development#GO:0007399;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;signaling#GO:0023052;synapse assembly#GO:0007416;animal gross anatomical part developmental process#GO:0160108;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;localization#GO:0051179;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;anatomical structure development#GO:0048856 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054;signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;cell projection membrane#GO:0031253;dendrite#GO:0030425;dendritic tree#GO:0097447;leading edge membrane#GO:0031256 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000042126.1|UniProtKB=A0A2I2ZTK3 A0A2I2ZTK3 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015252.3|UniProtKB=G3RGX3 G3RGX3 DDX23 PTHR47958:SF96 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX23-RELATED ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000000948.3|UniProtKB=A0A2I2YKU8 A0A2I2YKU8 AK1 PTHR23359:SF59 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 GORGO|Ensembl=ENSGGOG00000001793.3|UniProtKB=G3QHE2 G3QHE2 PTCD3 PTHR16276:SF1 PENTATRICOPEPTIDE REPEAT DOMAIN-CONTAINING PROTEIN 3 SMALL RIBOSOMAL SUBUNIT PROTEIN MS39 protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016593.3|UniProtKB=G3RKC3 G3RKC3 SRD5A1 PTHR10556:SF57 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;regulation of biological quality#GO:0065008;steroid biosynthetic process#GO:0006694;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;hormone biosynthetic process#GO:0042446;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000017023.3|UniProtKB=G3RLG5 G3RLG5 CDKN2C PTHR24201:SF9 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR C enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857 regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;negative regulation of cell population proliferation#GO:0008285;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;regulation of cell population proliferation#GO:0042127;regulation of mitotic cell cycle phase transition#GO:1901990 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000022744.2|UniProtKB=A0A2I2ZST5 A0A2I2ZST5 LOC101137887 PTHR26450:SF18 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043902.1|UniProtKB=A0A2I2YK11 A0A2I2YK11 SLAMF8 PTHR12080:SF92 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune system process#GO:0002376;cell communication#GO:0007154;immune response#GO:0006955;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000025188.2|UniProtKB=A0A2I2ZMF9 A0A2I2ZMF9 PRPF18 PTHR13007:SF19 PRE-MRNA SPLICING FACTOR-RELATED PRE-MRNA-SPLICING FACTOR 18 mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826 U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000024052.2|UniProtKB=G3S567 G3S567 LOC101131879 PTHR26450:SF32 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52B6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011116.3|UniProtKB=A0A2I2YT81 A0A2I2YT81 TTC3 PTHR17550:SF6 E3 UBIQUITIN-PROTEIN LIGASE TTC3 E3 UBIQUITIN-PROTEIN LIGASE TTC3 catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000040429.1|UniProtKB=A0A2I2ZJZ9 A0A2I2ZJZ9 LCNL1 PTHR11430:SF77 LIPOCALIN LIPOCALIN-LIKE 1 PROTEIN transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000042535.1|UniProtKB=G3RNQ3 G3RNQ3 DND1 PTHR21245:SF4 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN DEAD END PROTEIN HOMOLOG 1 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004829.3|UniProtKB=G3QQ72 G3QQ72 FBXO27 PTHR12125:SF9 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 27 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000205.3|UniProtKB=G3QD92 G3QD92 PTHR24026:SF36 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 1 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;axon development#GO:0061564;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 cell-cell junction#GO:0005911;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000010774.3|UniProtKB=G3SC39 G3SC39 CGAS PTHR10656:SF35 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;positive regulation of response to biotic stimulus#GO:0002833;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;negative regulation of cellular process#GO:0048523;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;positive regulation of type I interferon production#GO:0032481;negative regulation of DNA recombination#GO:0045910;regulation of double-strand break repair#GO:2000779;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;negative regulation of DNA metabolic process#GO:0051053;cellular response to nitrogen compound#GO:1901699;positive regulation of innate immune response#GO:0045089;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of response to stress#GO:0080134;regulation of response to biotic stimulus#GO:0002831;positive regulation of cytokine production#GO:0001819;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of multicellular organismal process#GO:0051239;response to chemical#GO:0042221;response to stress#GO:0006950;positive regulation of response to external stimulus#GO:0032103;negative regulation of double-strand break repair via homologous recombination#GO:2000042;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of DNA metabolic process#GO:0051052;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;cellular response to stress#GO:0033554;regulation of DNA recombination#GO:0000018 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 nucleotidyltransferase#PC00174;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000011975.3|UniProtKB=G3R8H0 G3R8H0 GUCY1A1 PTHR45655:SF4 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT ALPHA-1 phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829 purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;response to abiotic stimulus#GO:0009628;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;response to oxygen levels#GO:0070482;nucleoside phosphate metabolic process#GO:0006753 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;catalytic complex#GO:1902494 cyclase#PC00079;guanylate cyclase#PC00114 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 GORGO|Ensembl=ENSGGOG00000037246.1|UniProtKB=G3SK56 G3SK56 PTHR24366:SF14 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IMMUNOGLOBULIN SUPERFAMILY CONTAINING LEUCINE-RICH REPEAT PROTEIN regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neurogenesis#GO:0050767;regulation of growth#GO:0040008;regulation of cellular process#GO:0050794;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;positive regulation of cell projection organization#GO:0031346;regulation of nervous system development#GO:0051960;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;regulation of cell growth#GO:0001558;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;regulation of anatomical structure size#GO:0090066;positive regulation of cell differentiation#GO:0045597;positive regulation of cell growth#GO:0030307;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of axonogenesis#GO:0050770;cellular component organization#GO:0016043;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;positive regulation of growth#GO:0045927;positive regulation of cellular component organization#GO:0051130;regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000008788.3|UniProtKB=G3SIL2 G3SIL2 EPS8L2 PTHR12287:SF20 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8-LIKE PROTEIN 2 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;positive regulation of cell projection organization#GO:0031346;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of intracellular signal transduction#GO:1902531;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344 ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;ruffle#GO:0001726;cell projection membrane#GO:0031253;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011860.3|UniProtKB=G3R865 G3R865 GPD1 PTHR11728:SF32 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)], CYTOPLASMIC oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000039208.1|UniProtKB=G3QK89 G3QK89 LOC101132797 PTHR47966:SF83 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED NAPSIN-A aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;extracellular region#GO:0005576 protease#PC00190;aspartic protease#PC00053 GORGO|Ensembl=ENSGGOG00000013775.3|UniProtKB=G3RD44 G3RD44 TBX5 PTHR11267:SF28 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;heart morphogenesis#GO:0003007;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell fate specification#GO:0001708;anatomical structure formation involved in morphogenesis#GO:0048646;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;heart development#GO:0007507 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 GORGO|Ensembl=ENSGGOG00000008082.3|UniProtKB=A0A2I2ZJL5 A0A2I2ZJL5 MYO7A PTHR22692:SF34 MYOSIN VII, XV MYOSIN VIIA actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000014605.3|UniProtKB=G3RF83 G3RF83 SFTA2 PTHR38500:SF1 SURFACTANT-ASSOCIATED PROTEIN 2 SURFACTANT-ASSOCIATED PROTEIN 2 surfactant#PC00212;structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000038692.1|UniProtKB=A0A2I2ZSF3 A0A2I2ZSF3 PTHR12548:SF20 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000043410.1|UniProtKB=G3S407 G3S407 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000005128.3|UniProtKB=G3QR00 G3QR00 IL16 PTHR48484:SF2 PRO-INTERLEUKIN-16 PRO-INTERLEUKIN-16 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125 Interleukin signaling pathway#P00036>Interleukin#P00970 GORGO|Ensembl=ENSGGOG00000013027.3|UniProtKB=G3RB83 G3RB83 MICAL2 PTHR23167:SF39 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL2 actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;cytoskeletal protein binding#GO:0008092;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 cellular component organization#GO:0016043;organelle organization#GO:0006996;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;actin cytoskeleton organization#GO:0030036;protein depolymerization#GO:0051261;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;actin filament-based process#GO:0030029;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012872.3|UniProtKB=A0A2I2Z1R9 A0A2I2Z1R9 ADGRA2 PTHR45930:SF1 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A2 regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;tube development#GO:0035295;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of Wnt signaling pathway#GO:0030177;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;regulation of signaling#GO:0023051;angiogenesis#GO:0001525;positive regulation of signaling#GO:0023056;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;central nervous system development#GO:0007417;circulatory system development#GO:0072359;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000006971.3|UniProtKB=G3QVP8 G3QVP8 NFKB2 PTHR24169:SF21 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P100 SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of nucleobase-containing compound metabolic process#GO:0019219;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to other organism#GO:0051707;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;non-canonical NF-kappaB signal transduction#GO:0038061;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;defense response to other organism#GO:0098542;intracellular signaling cassette#GO:0141124;immune system process#GO:0002376;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to peptide#GO:1901652;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;B cell activation#P00010>NFkappaB#P00370;Apoptosis signaling pathway#P00006>NFkappaB#P00297;Toll receptor signaling pathway#P00054>NFkappaB#P01354;T cell activation#P00053>NFkappaB#P01298 GORGO|Ensembl=ENSGGOG00000024256.2|UniProtKB=A0A2I2YS32 A0A2I2YS32 LOC101144526 PTHR24031:SF700 RNA HELICASE RNA HELICASE translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;cytoplasmic stress granule#GO:0010494;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000043142.1|UniProtKB=G3RHT8 G3RHT8 PAGR1 PTHR28467:SF1 PAXIP1-ASSOCIATED GLUTAMATE-RICH PROTEIN 1 PAXIP1-ASSOCIATED GLUTAMATE-RICH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000023520.2|UniProtKB=G3SIN0 G3SIN0 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000040766.1|UniProtKB=A0A2I2YT48 A0A2I2YT48 LOC101131688 PTHR46315:SF4 SPERMINE SYNTHASE PABS DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058 GORGO|Ensembl=ENSGGOG00000006374.2|UniProtKB=G3QU42 G3QU42 PTHR10117:SF6 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 2 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;binding#GO:0005488;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178;transporter activity#GO:0005215;channel activity#GO:0015267;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262 sexual reproduction#GO:0019953;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of cytosolic calcium ion concentration#GO:0051480;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;fertilization#GO:0009566;reproductive process#GO:0022414;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;single fertilization#GO:0007338;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 GORGO|Ensembl=ENSGGOG00000013464.3|UniProtKB=A0A2I2YH41 A0A2I2YH41 TRIML2 PTHR24103:SF561 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML2-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011587.3|UniProtKB=G3R7G9 G3R7G9 HDAC8 PTHR10625:SF14 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 8 deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 Wnt signaling pathway#P00057>Histone deacetylase#P01472 GORGO|Ensembl=ENSGGOG00000000286.3|UniProtKB=G3QDG3 G3QDG3 HBEGF PTHR10740:SF4 TRANSFORMING GROWTH FACTOR ALPHA PROHEPARIN-BINDING EGF-LIKE GROWTH FACTOR signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;heparin binding#GO:0008201;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;carbohydrate derivative binding#GO:0097367;molecular function activator activity#GO:0140677;protein binding#GO:0005515;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102;binding#GO:0005488 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cellular component organization#GO:0051130;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;positive regulation of organelle organization#GO:0010638;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;signaling#GO:0023052;positive regulation of mitotic nuclear division#GO:0045840;cell surface receptor signaling pathway#GO:0007166;regulation of mitotic nuclear division#GO:0007088;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;ERBB signaling pathway#GO:0038127;epidermal growth factor receptor signaling pathway#GO:0007173;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of nuclear division#GO:0051783;positive regulation of cell cycle#GO:0045787 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 growth factor#PC00112 CCKR signaling map#P06959>HBEGF#P07025;CCKR signaling map#P06959>HBEGF#G07261;CCKR signaling map#P06959>HBEGF#G06968;EGF receptor signaling pathway#P00018>EGF#P00549;CCKR signaling map#P06959>Pro HBEGF#P07182 GORGO|Ensembl=ENSGGOG00000000327.4|UniProtKB=A0A2I2YKW2 A0A2I2YKW2 MDGA2 PTHR42757:SF34 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED MAM DOMAIN CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR 2 cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000041006.1|UniProtKB=A0A2I2Z796 A0A2I2Z796 PRSS54 PTHR24256:SF577 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 54 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000009819.3|UniProtKB=G3SAF1 G3SAF1 COLEC11 PTHR24024:SF14 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A COLLECTIN-11 molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;humoral immune response#GO:0006959;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;complement activation#GO:0006956;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;immune response#GO:0006955;activation of immune response#GO:0002253;defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211;surfactant#PC00212 GORGO|Ensembl=ENSGGOG00000004636.3|UniProtKB=G3QPP0 G3QPP0 SPN PTHR35265:SF1 LEUKOSIALIN LEUKOSIALIN GORGO|Ensembl=ENSGGOG00000000229.3|UniProtKB=G3QDB4 G3QDB4 MS4A8 PTHR23320:SF155 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 8 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000028607.2|UniProtKB=G3RWB3 G3RWB3 PTHR23049:SF36 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 10 calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;mitochondrion#GO:0005739;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000038959.1|UniProtKB=A0A2I2YBZ6 A0A2I2YBZ6 C2H3orf70 PTHR31785:SF2 UPF0524 PROTEIN C3ORF70 UPF0524 PROTEIN C3ORF70 nervous system development#GO:0007399;multicellular organismal process#GO:0032501;circadian rhythm#GO:0007623;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;rhythmic process#GO:0048511;animal gross anatomical part developmental process#GO:0160108 GORGO|Ensembl=ENSGGOG00000008168.3|UniProtKB=G3QYP6 G3QYP6 TADA1 PTHR21277:SF5 TRANSCRIPTIONAL ADAPTER 1 TRANSCRIPTIONAL ADAPTER 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;SAGA complex#GO:0000124;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000005459.3|UniProtKB=G3QRT6 G3QRT6 TBC1D8 PTHR22957:SF260 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 8 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000001407.3|UniProtKB=A0A2I2ZDR2 A0A2I2ZDR2 MARCHF9 PTHR46053:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF9 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000274.3|UniProtKB=G3QDF4 G3QDF4 SERPINI1 PTHR11461:SF50 SERINE PROTEASE INHIBITOR, SERPIN NEUROSERPIN enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000015013.3|UniProtKB=G3RGB0 G3RGB0 TM6SF1 PTHR14568:SF10 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 TRANSMEMBRANE 6 SUPERFAMILY MEMBER 1 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004239.4|UniProtKB=A0A2I2YBP3 A0A2I2YBP3 TPO PTHR11475:SF60 OXIDASE/PEROXIDASE THYROID PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 phenol-containing compound metabolic process#GO:0018958;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;metabolic process#GO:0008152;regulation of biological quality#GO:0065008 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000011428.3|UniProtKB=G3R724 G3R724 SEMA5A PTHR11036:SF78 SEMAPHORIN SEMAPHORIN-5A signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cellular developmental process#GO:0048869;developmental growth#GO:0048589;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;regulation of cellular process#GO:0050794;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;cell growth#GO:0016049;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;axon extension#GO:0048675;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron projection extension#GO:1990138;neuron development#GO:0048666;axonogenesis#GO:0007409;developmental growth involved in morphogenesis#GO:0060560;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000011154.3|UniProtKB=G3R6D2 G3R6D2 ADGRF3 PTHR45813:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F3 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000004267.3|UniProtKB=A0A2I2Z2S6 A0A2I2Z2S6 STK25 PTHR48012:SF9 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 25 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023838.2|UniProtKB=G3SEH5 G3SEH5 PTHR48029:SF6 NUCLEOLAR PROTEIN 8 NUCLEOLAR PROTEIN 8 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000012198.3|UniProtKB=G3R925 G3R925 INKA1 PTHR28615:SF1 PAK4-INHIBITOR INKA1-RELATED PAK4-INHIBITOR INKA1 molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000008693.3|UniProtKB=G3R024 G3R024 FRMPD4 PTHR46221:SF4 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4 phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic spine#GO:0043197;neuron projection#GO:0043005;postsynapse#GO:0098794;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 GORGO|Ensembl=ENSGGOG00000006033.3|UniProtKB=G3RLR3 G3RLR3 ZNF101 PTHR24379:SF70 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 101 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000011085.3|UniProtKB=A0A2I2ZLH2 A0A2I2ZLH2 SIK3 PTHR24346:SF42 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE SIK3 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000011437.3|UniProtKB=A0A2I2Y8V7 A0A2I2Y8V7 SLC35A2 PTHR10231:SF106 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-GALACTOSE TRANSLOCATOR transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;UDP-galactose transmembrane transporter activity#GO:0005459;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;nucleotide-sugar transmembrane transport#GO:0015780;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013213.3|UniProtKB=A0A2I2ZCV6 A0A2I2ZCV6 DSP PTHR23169:SF26 ENVOPLAKIN DESMOPLAKIN anatomical structure development#GO:0048856;wound healing#GO:0042060;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;cell adhesion#GO:0007155;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;skin development#GO:0043588;cytoskeleton organization#GO:0007010;cell-cell adhesion#GO:0098609;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intercalated disc#GO:0014704;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;cell-cell contact zone#GO:0044291;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054 intermediate filament#PC00129;intermediate filament binding protein#PC00130 GORGO|Ensembl=ENSGGOG00000003396.3|UniProtKB=G3QLI0 G3QLI0 MBOAT4 PTHR13906:SF3 PORCUPINE MEMBRANE-BOUND GHRELIN O-ACYLTRANSFERASE MBOAT4 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid modification#GO:0030258;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000002629.4|UniProtKB=A0A2I2ZRH9 A0A2I2ZRH9 GPM6A PTHR11683:SF4 MYELIN PROTEOLIPID NEURONAL MEMBRANE GLYCOPROTEIN M6-A plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;neurogenesis#GO:0022008;regulation of filopodium assembly#GO:0051489;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cell projection assembly#GO:0060491;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;filopodium#GO:0030175;intracellular organelle#GO:0043229;axon#GO:0030424;growth cone#GO:0030426;axonal growth cone#GO:0044295;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;cell body#GO:0044297;actin-based cell projection#GO:0098858;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000008050.3|UniProtKB=G3SIK2 G3SIK2 HPRT1 PTHR43340:SF6 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE metal ion binding#GO:0046872;cation binding#GO:0043169;magnesium ion binding#GO:0000287;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247;Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245 GORGO|Ensembl=ENSGGOG00000015093.3|UniProtKB=G3RGJ0 G3RGJ0 SAFB2 PTHR15683:SF4 SCAFFOLD ATTACHMENT FACTOR B-RELATED SCAFFOLD ATTACHMENT FACTOR B2 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012404.3|UniProtKB=G3S6M5 G3S6M5 EPRS1 PTHR43382:SF2 PROLYL-TRNA SYNTHETASE BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 GORGO|Ensembl=ENSGGOG00000001509.3|UniProtKB=G3QGN0 G3QGN0 PTHR24377:SF982 IP01015P-RELATED ZINC FINGER PROTEIN 223 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011301.3|UniProtKB=G3R6P8 G3R6P8 IKZF2 PTHR24404:SF33 ZINC FINGER PROTEIN ZINC FINGER PROTEIN HELIOS transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007423.3|UniProtKB=G3QWU8 G3QWU8 SLC7A8 PTHR11785:SF113 AMINO ACID TRANSPORTER LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 2 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175 cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;amino acid transport#GO:0006865;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025401.2|UniProtKB=G3RM01 G3RM01 OR1J1 PTHR26453:SF626 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008360.3|UniProtKB=G3RYN0 G3RYN0 MAP3K4 PTHR48016:SF32 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 4 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;p38MAPK cascade#GO:0038066;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Oxidative stress response#P00046>MKK4#P01138;p38 MAPK pathway#P05918>MEKK4#P06026;FGF signaling pathway#P00021>MEKK1-5#P00634;Integrin signalling pathway#P00034>ERK#P00907;Interleukin signaling pathway#P00036>MEK#P00984;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;Ras Pathway#P04393>MEKK1/4#P04543;PDGF signaling pathway#P00047>ERK#P01143;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 GORGO|Ensembl=ENSGGOG00000014932.3|UniProtKB=A0A2I2YJF5 A0A2I2YJF5 CCDC154 PTHR35153:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 154 COILED-COIL DOMAIN-CONTAINING PROTEIN 154 anatomical structure maturation#GO:0071695;bone development#GO:0060348;tissue development#GO:0009888;multicellular organismal process#GO:0032501;ossification#GO:0001503;developmental maturation#GO:0021700;bone mineralization#GO:0030282;animal gross anatomical part developmental process#GO:0160108;biomineral tissue development#GO:0031214;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;system development#GO:0048731 GORGO|Ensembl=ENSGGOG00000011645.4|UniProtKB=A0A2I2ZLV7 A0A2I2ZLV7 ZFPM2 PTHR12958:SF5 FRIEND OF GATA2-RELATED ZINC FINGER PROTEIN ZFPM2 transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription regulator activity#GO:0140110;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297 multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;heart development#GO:0007507;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000015254.3|UniProtKB=A0A2I2ZXA0 A0A2I2ZXA0 PTHR43128:SF17 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) LACTATE_MALATE DEHYDROGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000013964.3|UniProtKB=G3RY68 G3RY68 LOC101130048 PTHR24257:SF24 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2A serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of cell adhesion#GO:0030155;cellular process#GO:0009987;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;regulation of platelet activation#GO:0010543;proteolysis#GO:0006508;regulation of platelet aggregation#GO:0090330;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015464.3|UniProtKB=G3RHG5 G3RHG5 ETS2 PTHR11849:SF188 ETS PROTEIN C-ETS-2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016989.3|UniProtKB=G3RLD6 G3RLD6 NAP1L3 PTHR11875:SF38 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 3 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000042098.1|UniProtKB=A0A2I2ZJQ0 A0A2I2ZJQ0 PTHR42874:SF1 URICASE URICASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;purine-containing compound catabolic process#GO:0072523;purine nucleobase catabolic process#GO:0006145;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000036451.1|UniProtKB=A0A2I2ZFA1 A0A2I2ZFA1 NEUROG3 PTHR19290:SF94 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-3 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000027170.2|UniProtKB=A0A2I2ZVA5 A0A2I2ZVA5 PTHR15952:SF13 EXPORTIN-T/LOS1 EXPORTIN-T binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA binding#GO:0000049;RNA binding#GO:0003723 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913 organelle envelope#GO:0031967;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015425.3|UniProtKB=G3RHD3 G3RHD3 SPARCL1 PTHR13866:SF16 SPARC OSTEONECTIN SPARC-LIKE PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;ear development#GO:0043583;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;regulation of synapse organization#GO:0050807;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;tube morphogenesis#GO:0035239;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tube development#GO:0035295;embryo development#GO:0009790;biological regulation#GO:0065007;inner ear development#GO:0048839;inner ear morphogenesis#GO:0042472 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000036657.1|UniProtKB=G3RDU4 G3RDU4 PMEL PTHR11861:SF1 MELANOCYTE PROTEIN PMEL 17-RELATED MELANOCYTE PROTEIN PMEL melanosome organization#GO:0032438;pigmentation#GO:0043473;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular pigmentation#GO:0033059 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;melanosome#GO:0042470;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000026323.2|UniProtKB=A0A2I2ZDN6 A0A2I2ZDN6 PTHR10722:SF24 60S RIBOSOMAL PROTEIN L19 RIBOSOMAL PROTEIN L19 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012923.3|UniProtKB=G3RAX8 G3RAX8 SHROOM2 PTHR15012:SF8 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM2 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;plasma membrane region#GO:0098590;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;membraneless organelle#GO:0043228;adherens junction#GO:0005912;apical junction complex#GO:0043296;cytoskeleton#GO:0005856;apical part of cell#GO:0045177 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000022820.2|UniProtKB=G3QH42 G3QH42 LOC101128212 PTHR21522:SF19 PROTON CHANNEL OTOP PROTON CHANNEL OTOP1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;identical protein binding#GO:0042802;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;binding#GO:0005488;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515 transmembrane transport#GO:0055085;anatomical structure development#GO:0048856;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;ear development#GO:0043583;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;biomineral tissue development#GO:0031214;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;proton transmembrane transport#GO:1902600;anatomical structure formation involved in morphogenesis#GO:0048646;sensory organ development#GO:0007423;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tissue development#GO:0009888;monoatomic ion transmembrane transport#GO:0034220;embryo development#GO:0009790;monoatomic cation transmembrane transport#GO:0098655;inner ear development#GO:0048839;inner ear morphogenesis#GO:0042472;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016841.3|UniProtKB=G3RTD4 G3RTD4 HSPB6 PTHR45640:SF36 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-6 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;protein folding#GO:0006457;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;response to stress#GO:0006950;response to heat#GO:0009408;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;protein maturation#GO:0051604;negative regulation of apoptotic process#GO:0043066;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000043890.1|UniProtKB=A0A2I2ZW23 A0A2I2ZW23 PTHR23266:SF285 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-45 antigen binding#GO:0003823;binding#GO:0005488 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000004527.3|UniProtKB=G3QPE6 G3QPE6 PGAM2 PTHR11931:SF8 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE 2 isomerase activity#GO:0016853;phosphoglycerate mutase activity#GO:0004619;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;intramolecular phosphotransferase activity#GO:0016868 monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 mutase#PC00160;isomerase#PC00135 Glycolysis#P00024>Phosphoglyceromutase#P00680 GORGO|Ensembl=ENSGGOG00000016554.3|UniProtKB=G3RK89 G3RK89 TMEM225 PTHR36477:SF1 TRANSMEMBRANE PROTEIN 225 TRANSMEMBRANE PROTEIN 225 GORGO|Ensembl=ENSGGOG00000006396.3|UniProtKB=G3QU62 G3QU62 MYBBP1A PTHR13213:SF3 MYB-BINDING PROTEIN 1A FAMILY MEMBER MYB-BINDING PROTEIN 1A DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000001071.3|UniProtKB=G3QFI3 G3QFI3 RAB11FIP4 PTHR15726:SF5 RAB11-FAMILY INTERACTING PROTEIN RAB11 FAMILY-INTERACTING PROTEIN 4 transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;endocytic recycling#GO:0032456 endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;cell division site#GO:0032153;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cleavage furrow#GO:0032154;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;recycling endosome#GO:0055037;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;midbody#GO:0030496;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000025598.2|UniProtKB=G3RZT9 G3RZT9 BRK1 PTHR33668:SF3 PROTEIN BRICK1 PROTEIN BRICK1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;regulation of cell projection assembly#GO:0060491;positive regulation of cell projection organization#GO:0031346;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of anatomical structure size#GO:0090066;regulation of actin nucleation#GO:0051125 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000022154.2|UniProtKB=G3S912 G3S912 WRN PTHR13710:SF166 DNA HELICASE RECQ FAMILY MEMBER BIFUNCTIONAL 3'-5' EXONUCLEASE_ATP-DEPENDENT HELICASE WRN catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;telomere organization#GO:0032200;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA helicase#PC00011 p53 pathway#P00059>WRN#P04617 GORGO|Ensembl=ENSGGOG00000015724.3|UniProtKB=G3RI51 G3RI51 NOX3 PTHR11972:SF12 NADPH OXIDASE NADPH OXIDASE 3 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987;response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801;defense response#GO:0006952 catalytic complex#GO:1902494;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidase#PC00175;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002763.3|UniProtKB=G3QJW6 G3QJW6 PPM1K PTHR47992:SF274 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE MN(2+)-DEPENDENT 1K catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023269.2|UniProtKB=A0A2I2YG68 A0A2I2YG68 CD68 PTHR11506:SF2 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN MACROSIALIN establishment of protein localization#GO:0045184;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;late endosome membrane#GO:0031902;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000009557.3|UniProtKB=G3R290 G3R290 DKK3 PTHR12113:SF8 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 3 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;binding#GO:0005488 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000001856.3|UniProtKB=G3QHJ8 G3QHJ8 SIAH3 PTHR45877:SF5 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 SEVEN IN ABSENTIA HOMOLOG 3 enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000024539.2|UniProtKB=G3RT57 G3RT57 POLR2K PTHR12056:SF4 DNA-DIRECTED RNA POLYMERASES I, II, AND III DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase I complex#GO:0005736;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 GORGO|Ensembl=ENSGGOG00000017067.3|UniProtKB=G3RLK6 G3RLK6 NEURL3 PTHR12429:SF9 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL3 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;protein transport#GO:0015031;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;protein localization to organelle#GO:0033365;regulation of response to stimulus#GO:0048583;transport#GO:0006810;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;import into cell#GO:0098657;establishment of protein localization to organelle#GO:0072594;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001364.3|UniProtKB=G3QG95 G3QG95 FYB1 PTHR16830:SF13 SH2 CONTAINING ADAPTOR PRAM-1 RELATED FYN-BINDING PROTEIN 1 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;localization#GO:0051179;cell communication#GO:0007154;regulation of immune response#GO:0050776;localization within membrane#GO:0051668;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;signaling#GO:0023052;protein localization to membrane#GO:0072657;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular localization#GO:0051641;immune system process#GO:0002376;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;protein localization to cell periphery#GO:1990778;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006045.3|UniProtKB=G3QTA1 G3QTA1 MAPK7 PTHR24055:SF561 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 7 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167 Parkinson disease#P00049>ERK#P01211;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;CCKR signaling map#P06959>MAPK7#P07021;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Interleukin signaling pathway#P00036>ERK#P00965;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Endothelin signaling pathway#P00019>ERK#P00566;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Apoptosis signaling pathway#P00006>MAPK#P00269;FGF signaling pathway#P00021>ERK1-2#P00627;PDGF signaling pathway#P00047>ERK#P01143 GORGO|Ensembl=ENSGGOG00000023942.2|UniProtKB=G3R6B6 G3R6B6 PTHR11749:SF19 RIBULOSE-5-PHOSPHATE-3-EPIMERASE RIBULOSE-PHOSPHATE 3-EPIMERASE-LIKE PROTEIN 1 isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;cation binding#GO:0043169;metal ion binding#GO:0046872;D-ribulose-phosphate 3-epimerase activity#GO:0004750;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;nucleobase-containing compound metabolic process#GO:0006139;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852 GORGO|Ensembl=ENSGGOG00000015076.3|UniProtKB=G3RGH3 G3RGH3 FRMPD2 PTHR19964:SF56 MULTIPLE PDZ DOMAIN PROTEIN FERM AND PDZ DOMAIN-CONTAINING PROTEIN 2 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840 cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;apical part of cell#GO:0045177;bicellular tight junction#GO:0005923;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;cytoplasm#GO:0005737;basolateral plasma membrane#GO:0016323;cell-cell junction#GO:0005911;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;basal part of cell#GO:0045178 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008714.3|UniProtKB=G3R042 G3R042 ELK1 PTHR11849:SF178 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ELK#P00890;CCKR signaling map#P06959>ELK1#P07146;Toll receptor signaling pathway#P00054>Elk1#P01341;p38 MAPK pathway#P05918>ELK#P06013;Interleukin signaling pathway#P00036>ELK#P00962;PDGF signaling pathway#P00047>ELK#P01140;Ras Pathway#P04393>Elk-1#P04573;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>ELK1#P05934;Gonadotropin-releasing hormone receptor pathway#P06664>ELK1#P06785;Oxidative stress response#P00046>Elk-1#P01136;Parkinson disease#P00049>Elk-1#P01233 GORGO|Ensembl=ENSGGOG00000008552.3|UniProtKB=G3RQT9 G3RQT9 GFRA1 PTHR10269:SF3 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;nervous system development#GO:0007399;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007872.3|UniProtKB=G3QXX6 G3QXX6 PCOLCE2 PTHR24251:SF31 OVOCHYMASE-RELATED PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER 2 collagen binding#GO:0005518;binding#GO:0005488;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504;molecular function regulator activity#GO:0098772 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000026769.2|UniProtKB=G3SB05 G3SB05 PTHR15909:SF0 39S RIBOSOMAL PROTEIN L35, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008231.3|UniProtKB=G3S8H0 G3S8H0 WDR26 PTHR22838:SF28 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 26 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000003623.3|UniProtKB=G3S4K5 G3S4K5 GDI2 PTHR11787:SF1 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR BETA molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000001749.3|UniProtKB=G3S1C7 G3S1C7 LPAR1 PTHR22750:SF22 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000011879.3|UniProtKB=G3R887 G3R887 PRIMPOL PTHR31399:SF0 DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN DNA-DIRECTED PRIMASE_POLYMERASE PROTEIN chromatin binding#GO:0003682;binding#GO:0005488;DNA-directed DNA polymerase activity#GO:0003887;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;mitochondrial DNA metabolic process#GO:0032042;DNA synthesis involved in DNA replication#GO:0090592;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;response to radiation#GO:0009314;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985;replication fork processing#GO:0031297;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;response to UV#GO:0009411;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000013059.3|UniProtKB=G3RBA0 G3RBA0 ERI1 PTHR23044:SF77 3'-5' EXONUCLEASE ERI1-RELATED 3'-5' EXORIBONUCLEASE 1 exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular component organization#GO:0051129;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;positive regulation of biosynthetic process#GO:0009891;regulation of chromatin organization#GO:1902275;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000006686.3|UniProtKB=G3QUX8 G3QUX8 CAMK2N1 PTHR31007:SF3 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 1 molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857 kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000004876.3|UniProtKB=G3SBT6 G3SBT6 GPR155 PTHR22829:SF5 DEP DOMAIN PROTEIN LYSOSOMAL CHOLESTEROL SIGNALING PROTEIN regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514;regulation of BMP signaling pathway#GO:0030510;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000028546.2|UniProtKB=G3RSL4 G3RSL4 PTHR11489:SF21 40S RIBOSOMAL PROTEIN SA 40S RIBOSOMAL PROTEIN SA structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;translation#GO:0006412;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000027616.2|UniProtKB=G3RWL7 G3RWL7 BOD1L1 PTHR47391:SF1 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 LIKE 1 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 LIKE 1 GORGO|Ensembl=ENSGGOG00000008228.3|UniProtKB=G3SH99 G3SH99 CYTH4 PTHR10663:SF323 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-4 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000042648.1|UniProtKB=A0A2I2YA23 A0A2I2YA23 MED31 PTHR13186:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004055.3|UniProtKB=G3QN70 G3QN70 SERPINA11 PTHR11461:SF154 SERINE PROTEASE INHIBITOR, SERPIN SERPIN A11 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000027337.2|UniProtKB=G3SA67 G3SA67 PFDN4 PTHR21100:SF9 PREFOLDIN SUBUNIT 4 PREFOLDIN SUBUNIT 4 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000002192.3|UniProtKB=G3QIE8 G3QIE8 LOC101131674 PTHR11588:SF43 TUBULIN TUBULIN BETA-3 CHAIN heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;tubulin#PC00228 Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780 GORGO|Ensembl=ENSGGOG00000012380.3|UniProtKB=A0A2I2YUD7 A0A2I2YUD7 MYO18A PTHR45615:SF13 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIA polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000039211.1|UniProtKB=A0A2I2Y633 A0A2I2Y633 CPLX2 PTHR16705:SF9 COMPLEXIN COMPLEXIN-2 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055;neurotransmitter transport#GO:0006836;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of signaling#GO:0023051;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;neuron projection terminus#GO:0044306;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;terminal bouton#GO:0043195;cellular anatomical structure#GO:0110165;synapse#GO:0045202;SNARE complex#GO:0031201;axon terminus#GO:0043679;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000000463.3|UniProtKB=G3QDX7 G3QDX7 MUC6 PTHR11339:SF264 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-6 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000002044.3|UniProtKB=G3QI18 G3QI18 USP38 PTHR24006:SF710 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 38 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000006419.3|UniProtKB=G3QU81 G3QU81 PPTC7 PTHR12320:SF98 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE PTC7 HOMOLOG regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 protein phosphatase#PC00195 GORGO|Gene=CAMP|UniProtKB=Q1KLY3 Q1KLY3 CAMP PTHR10206:SF2 CATHELICIDIN CATHELICIDIN ANTIMICROBIAL PEPTIDE lipid binding#GO:0008289;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;lipopolysaccharide binding#GO:0001530 response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000034956.2|UniProtKB=G3SKU6 G3SKU6 HBS1L PTHR23115:SF188 TRANSLATION FACTOR HBS1-LIKE PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;rescue of stalled cytosolic ribosome#GO:0072344;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;translation#GO:0006412;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000008457.3|UniProtKB=G3QZF7 G3QZF7 ADRM1 PTHR12225:SF0 ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000008620.3|UniProtKB=G3QZV8 G3QZV8 TMIGD1 PTHR12231:SF219 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell migration#GO:0016477;cell motility#GO:0048870;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000015369.3|UniProtKB=G3RH78 G3RH78 USP42 PTHR24006:SF727 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 42 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 regulation of protein stability#GO:0031647;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000023721.2|UniProtKB=G3S626 G3S626 PTHR48051:SF12 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 28 ISOFORM X1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000163.3|UniProtKB=G3QD53 G3QD53 TTC13 PTHR44523:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 13 TETRATRICOPEPTIDE REPEAT PROTEIN 13 GORGO|Ensembl=ENSGGOG00000016419.3|UniProtKB=A0A2I2Z3B1 A0A2I2Z3B1 CLCN5 PTHR45711:SF7 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 5 gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 system process#GO:0003008;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;renal system process#GO:0003014;monoatomic anion transport#GO:0006820 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014335.3|UniProtKB=A0A2I2ZV90 A0A2I2ZV90 USP37 PTHR24006:SF686 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 37 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824 mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;regulation of biological quality#GO:0065008;cell cycle#GO:0007049;regulation of protein stability#GO:0031647;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000014212.3|UniProtKB=G3S018 G3S018 PSD2 PTHR10663:SF329 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 2 leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;cell projection membrane#GO:0031253;ruffle#GO:0001726;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000014649.3|UniProtKB=G3RFC7 G3RFC7 PLBD2 PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000001095.3|UniProtKB=G3QFK2 G3QFK2 TFB2M PTHR11727:SF13 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 2, MITOCHONDRIAL N-methyltransferase activity#GO:0008170;transcription regulator activity#GO:0140110;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;DNA-templated transcription initiation#GO:0006352;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mitochondrial transcription#GO:0006390;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;rRNA processing#GO:0006364;mitochondrial gene expression#GO:0140053;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;mitochondrial RNA metabolic process#GO:0000959 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000015098.3|UniProtKB=G3RPY2 G3RPY2 LOC101152267 PTHR11524:SF12 60S RIBOSOMAL PROTEIN L7 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001633.4|UniProtKB=A0A2I2Z0F8 A0A2I2Z0F8 SLCO3A1 PTHR11388:SF86 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 3A1 active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987;localization#GO:0051179;fatty acid transport#GO:0015908;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025256.2|UniProtKB=A0A2I2YCJ3 A0A2I2YCJ3 PTHR11599:SF16 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-2 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;peptidase complex#GO:1905368;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000024980.2|UniProtKB=G3RWU0 G3RWU0 SLC25A46 PTHR21252:SF2 TB1 PROTEIN-RELATED MITOCHONDRIAL OUTER MEMBRANE PROTEIN SLC25A46 neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;organelle fission#GO:0048285;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;developmental process#GO:0032502;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;mitochondrion organization#GO:0007005;multicellular organismal process#GO:0032501;mitochondrial fission#GO:0000266;cellular process#GO:0009987;axon development#GO:0061564;organelle organization#GO:0006996;neuron projection development#GO:0031175 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967 GORGO|Ensembl=ENSGGOG00000038771.1|UniProtKB=A0A2I2ZLS7 A0A2I2ZLS7 PTHR12172:SF3 CELL CYCLE CHECKPOINT PROTEIN RAD17 CHECKPOINT PROTEIN RAD24-LIKE HELICAL BUNDLE DOMAIN-CONTAINING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;mitotic DNA replication checkpoint signaling#GO:0033314;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554 membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;site of double-strand break#GO:0035861;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;chromosome, telomeric repeat region#GO:0140445;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000001492.3|UniProtKB=G3QGL3 G3QGL3 APCS PTHR45869:SF5 C-REACTIVE PROTEIN-RELATED SERUM AMYLOID P-COMPONENT protein binding#GO:0005515;protein-containing complex binding#GO:0044877;complement binding#GO:0001848;binding#GO:0005488 defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;inflammatory response#GO:0006954;immune system process#GO:0002376;defense response#GO:0006952;acute inflammatory response#GO:0002526;response to external stimulus#GO:0009605;innate immune response#GO:0045087 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000039063.1|UniProtKB=A0A2I2ZY74 A0A2I2ZY74 PTHR23415:SF35 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 cell cycle#GO:0007049;mitotic cell cycle phase transition#GO:0044772;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;mitotic cell cycle process#GO:1903047 transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012028.3|UniProtKB=G3R8L6 G3R8L6 PTHR38648:SF1 RIKEN CDNA 4930451I11 GENE FERTILIZATION-INFLUENCING MEMBRANE PROTEIN single fertilization#GO:0007338;cellular process#GO:0009987;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;fertilization#GO:0009566;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609 GORGO|Ensembl=ENSGGOG00000014784.3|UniProtKB=G3RFQ0 G3RFQ0 PTHR23503:SF99 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;import across plasma membrane#GO:0098739;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000008849.4|UniProtKB=G3R0G8 G3R0G8 QSER1 PTHR14709:SF2 GLUTAMINE AND SERINE-RICH PROTEIN 1-RELATED GLUTAMINE AND SERINE-RICH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000009614.3|UniProtKB=G3R2E7 G3R2E7 SND1 PTHR12302:SF2 EBNA2 BINDING PROTEIN P100 STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000008561.3|UniProtKB=G3QZQ0 G3QZQ0 RAB42 PTHR47979:SF5 DRAB11-RELATED RAS-RELATED PROTEIN RAB-42 small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000005673.3|UniProtKB=G3RU79 G3RU79 KNOP1 PTHR22426:SF4 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 LYSINE-RICH NUCLEOLAR PROTEIN 1 GORGO|Ensembl=ENSGGOG00000015662.3|UniProtKB=G3RI08 G3RI08 FIG4 PTHR45738:SF5 POLYPHOSPHOINOSITIDE PHOSPHATASE POLYPHOSPHOINOSITIDE PHOSPHATASE phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;dephosphorylation#GO:0016311;lipid modification#GO:0030258;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000011950.3|UniProtKB=G3R8F1 G3R8F1 SLC16A10 PTHR11360:SF119 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 10 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 hormone transport#GO:0009914;transport#GO:0006810;regulation of hormone levels#GO:0010817;establishment of localization#GO:0051234;localization#GO:0051179;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000027435.2|UniProtKB=A0A2I2ZKP0 A0A2I2ZKP0 FOXP2 PTHR45796:SF9 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P2 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;muscle tissue development#GO:0060537;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;skeletal muscle tissue development#GO:0007519;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;tissue development#GO:0009888;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000010387.3|UniProtKB=G3R4D1 G3R4D1 PTHR23320:SF153 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 6E cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025823.2|UniProtKB=A0A2I2Z280 A0A2I2Z280 PTPRC PTHR19134:SF539 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 protein modifying enzyme#PC00260;protein phosphatase#PC00195 T cell activation#P00053>CD45#P01329;B cell activation#P00010>CD45#P00396;JAK/STAT signaling pathway#P00038>PTP#P01033 GORGO|Ensembl=ENSGGOG00000010475.3|UniProtKB=G3R4K8 G3R4K8 TIGD7 PTHR19303:SF17 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 7 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000022669.2|UniProtKB=A0A2I2YPF1 A0A2I2YPF1 CNPY1 PTHR13341:SF4 MIR-INTERACTING SAPOSIN-LIKE PROTEIN CANOPY FGF SIGNALING REGULATOR 1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000025243.2|UniProtKB=G3SHK2 G3SHK2 BMI1 PTHR10825:SF21 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB COMPLEX PROTEIN BMI-1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;PcG protein complex#GO:0031519;nucleus#GO:0005634 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000015073.3|UniProtKB=G3RGG0 G3RGG0 DCAF8L1 PTHR15574:SF29 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 8-LIKE PROTEIN 1 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000015112.3|UniProtKB=G3RGJ9 G3RGJ9 ITPKB PTHR12400:SF4 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE B phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000003418.3|UniProtKB=G3QLK6 G3QLK6 FARSA PTHR11538:SF40 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000005447.3|UniProtKB=G3QRS1 G3QRS1 SSC4D PTHR19331:SF439 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING GROUP B PROTEIN cargo receptor activity#GO:0038024 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000026899.2|UniProtKB=G3RXB1 G3RXB1 ZNF787 PTHR14003:SF32 TRANSCRIPTIONAL REPRESSOR PROTEIN YY ZKSCAN8 PSEUDOGENE 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022601.2|UniProtKB=G3RP87 G3RP87 APOC2 PTHR32288:SF0 APOLIPOPROTEIN C-IV APOLIPOPROTEIN C-IV triglyceride homeostasis#GO:0070328;lipid homeostasis#GO:0055088;lipid storage#GO:0019915;chemical homeostasis#GO:0048878;cellular process#GO:0009987;homeostatic process#GO:0042592 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;very-low-density lipoprotein particle#GO:0034361;plasma lipoprotein particle#GO:0034358;high-density lipoprotein particle#GO:0034364;protein-lipid complex#GO:0032994;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;lipoprotein particle#GO:1990777 apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000006759.3|UniProtKB=G3QV49 G3QV49 HSDL2 PTHR42808:SF3 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000011792.3|UniProtKB=G3R7Z8 G3R7Z8 EIF1AD PTHR21641:SF0 TRANSLATION INITIATION FACTOR-RELATED RNA-BINDING PROTEIN EIF1AD-RELATED cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000001504.3|UniProtKB=A0A2I2ZR33 A0A2I2ZR33 FAM120C PTHR15976:SF15 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 2 GORGO|Ensembl=ENSGGOG00000036493.1|UniProtKB=A0A2I2Y618 A0A2I2Y618 RND2 PTHR24072:SF21 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHON nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rho#P00948 GORGO|Ensembl=ENSGGOG00000012629.3|UniProtKB=G3SB86 G3SB86 CHRDL2 PTHR46303:SF3 VWFC DOMAIN-CONTAINING PROTEIN CHORDIN-LIKE PROTEIN 2 protein binding#GO:0005515;cytokine binding#GO:0019955;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000012058.3|UniProtKB=G3R8Q3 G3R8Q3 ZBTB17 PTHR24379:SF134 KRAB AND ZINC FINGER DOMAIN-CONTAINING RIKEN CDNA 2610008E11 GENE LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000027979.2|UniProtKB=G3S6R0 G3S6R0 PTHR47958:SF70 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000014787.3|UniProtKB=G3RFQ1 G3RFQ1 CLDND2 PTHR10671:SF30 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN DOMAIN-CONTAINING PROTEIN 2 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000017042.3|UniProtKB=G3RLI1 G3RLI1 MPST PTHR11364:SF25 THIOSULFATE SULFERTANSFERASE 3-MERCAPTOPYRUVATE SULFURTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;transferase activity#GO:0016740;catalytic activity#GO:0003824 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA wobble position uridine thiolation#GO:0002143;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000038854.1|UniProtKB=A0A2I2YAI3 A0A2I2YAI3 PTHR10223:SF8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 VWFA DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000008545.3|UniProtKB=G3QZN9 G3QZN9 CLEC1A PTHR46490:SF1 C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 1 MEMBER A transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000015512.3|UniProtKB=A0A2I2YBC4 A0A2I2YBC4 GLOD4 PTHR46466:SF1 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000007707.3|UniProtKB=G3QXJ6 G3QXJ6 PTHR16675:SF268 MHC CLASS I-RELATED UL16-BINDING PROTEIN 1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 natural killer cell mediated cytotoxicity#GO:0042267;immune effector process#GO:0002252;defense response to other organism#GO:0098542;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of cell killing#GO:0031341;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;leukocyte mediated cytotoxicity#GO:0001909;natural killer cell mediated immunity#GO:0002228;regulation of biological process#GO:0050789;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;cell killing#GO:0001906;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;regulation of leukocyte mediated immunity#GO:0002703 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000005148.3|UniProtKB=A0A2I2ZNA1 A0A2I2ZNA1 GSTM4 PTHR11571:SF137 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 4 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000011259.3|UniProtKB=A0A2I2ZFU0 A0A2I2ZFU0 SLFN5 PTHR12155:SF26 SCHLAFEN SCHLAFEN FAMILY MEMBER 5 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000023745.2|UniProtKB=A0A2I2YYA4 A0A2I2YYA4 RPS21 PTHR10442:SF9 40S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN ES21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;translation#GO:0006412;protein metabolic process#GO:0019538;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000011054.3|UniProtKB=G3R636 G3R636 CDK9 PTHR24056:SF233 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 9 protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004224.3|UniProtKB=G3QNM5 G3QNM5 FHL5 PTHR24205:SF7 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 5 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000023657.2|UniProtKB=G3RR18 G3RR18 TRIAP1 PTHR46403:SF3 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 localization#GO:0051179;lipid localization#GO:0010876;regulation of cellular process#GO:0050794;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;transport#GO:0006810;regulation of apoptotic process#GO:0042981;lipid transport#GO:0006869;negative regulation of apoptotic process#GO:0043066;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;intermembrane phospholipid transfer#GO:0120010;macromolecule localization#GO:0033036;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000016855.3|UniProtKB=G3RL16 G3RL16 LOC101139245 PTHR24291:SF149 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4B1 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000040156.1|UniProtKB=A0A2I2ZKU7 A0A2I2ZKU7 PTHR10462:SF26 GLYCOSYLTRANSFERASE-RELATED N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000005111.3|UniProtKB=A0A2I2ZR39 A0A2I2ZR39 PPWD1 PTHR45625:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000015672.3|UniProtKB=G3RI19 G3RI19 TAF1 PTHR13900:SF0 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1 binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058 RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transferase complex#GO:1990234;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000009318.3|UniProtKB=G3R1M3 G3R1M3 RFTN2 PTHR17601:SF1 RAFTLIN-RELATED RAFTLIN-2 GORGO|Ensembl=ENSGGOG00000001621.3|UniProtKB=G3QGY1 G3QGY1 KCNRG PTHR14499:SF5 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL REGULATORY PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011320.3|UniProtKB=G3R6S4 G3R6S4 SSH3 PTHR45864:SF4 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 3 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824 regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 GORGO|Ensembl=ENSGGOG00000009842.3|UniProtKB=G3R303 G3R303 RING1 PTHR46076:SF6 E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RING1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;chromatin binding#GO:0003682;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;PcG protein complex#GO:0031519;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000006758.3|UniProtKB=G3QV45 G3QV45 CRK PTHR19969:SF8 SH2-SH3 ADAPTOR PROTEIN-RELATED ADAPTER MOLECULE CRK molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>CRK#P07125;Integrin signalling pathway#P00034>Crk#P00933;Angiogenesis#P00005>Crk#P00207 GORGO|Ensembl=ENSGGOG00000002081.3|UniProtKB=G3QI49 G3QI49 ACADS PTHR43884:SF42 ACYL-COA DEHYDROGENASE SHORT-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;short-chain fatty acid catabolic process#GO:0019626;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000022904.2|UniProtKB=G3SB20 G3SB20 PTHR47979:SF5 DRAB11-RELATED RAS-RELATED PROTEIN RAB-42 nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000008367.3|UniProtKB=G3S996 G3S996 DHRS7 PTHR44269:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000016201.3|UniProtKB=A0A2I2ZY16 A0A2I2ZY16 AKAP4 PTHR10226:SF8 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488;protein kinase A binding#GO:0051018 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;enzyme-linked receptor protein signaling pathway#GO:0007167;localization#GO:0051179;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 sperm principal piece#GO:0097228;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011856.3|UniProtKB=G3R863 G3R863 TMEM39A PTHR12995:SF3 FI21814P1 TRANSMEMBRANE PROTEIN 39A negative regulation of catabolic process#GO:0009895;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of autophagosome assembly#GO:2000785;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of macroautophagy#GO:0016241;regulation of autophagosome maturation#GO:1901096;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;negative regulation of macroautophagy#GO:0016242;regulation of metabolic process#GO:0019222;regulation of protein-containing complex disassembly#GO:0043244 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000001393.4|UniProtKB=G3QGC5 G3QGC5 OS9 PTHR15414:SF5 OS-9-RELATED PROTEIN OS-9 biological regulation#GO:0065007;macromolecule localization#GO:0033036;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;localization#GO:0051179;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of biological process#GO:0050789;response to unfolded protein#GO:0006986;cellular localization#GO:0051641;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788 GORGO|Ensembl=ENSGGOG00000010963.3|UniProtKB=G3R5V4 G3R5V4 PTHR11003:SF353 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 1 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000028426.2|UniProtKB=G3RQG5 G3RQG5 RASSF9 PTHR15286:SF10 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 9 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;cytosol#GO:0005829;clathrin-coated vesicle membrane#GO:0030665;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle#GO:0030136;trans-Golgi network transport vesicle membrane#GO:0012510;recycling endosome#GO:0055037;Golgi-associated vesicle#GO:0005798;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;trans-Golgi network transport vesicle#GO:0030140;endosome#GO:0005768;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005648.3|UniProtKB=G3QS99 G3QS99 MTG2 PTHR11702:SF31 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007017.3|UniProtKB=G3QVT3 G3QVT3 C4H17orf99 PTHR11481:SF67 IMMUNOGLOBULIN FC RECEPTOR PROTEIN IL-40 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000011051.3|UniProtKB=A0A2I2Z0T3 A0A2I2Z0T3 TNFRSF10B PTHR46330:SF18 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B death receptor activity#GO:0005035;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell death#GO:0008219;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;apoptotic signaling pathway#GO:0097190;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of apoptotic process#GO:0043065 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 p53 pathway#P00059>KILLER/DR5#G01568;Apoptosis signaling pathway#P00006>TRAIL-R#P00276 GORGO|Ensembl=ENSGGOG00000015897.3|UniProtKB=G3RIK0 G3RIK0 PEF1 PTHR46212:SF10 PEFLIN PEFLIN Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;vesicle budding from membrane#GO:0006900;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043 GORGO|Ensembl=ENSGGOG00000006951.3|UniProtKB=G3QVM9 G3QVM9 CTPS2 PTHR11550:SF2 CTP SYNTHASE CTP SYNTHASE 2 ligase activity, forming carbon-nitrogen bonds#GO:0016879;identical protein binding#GO:0042802;protein binding#GO:0005515;ligase activity#GO:0016874;binding#GO:0005488;catalytic activity#GO:0003824 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;pyrimidine nucleobase metabolic process#GO:0006206;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112 supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931 GORGO|Ensembl=ENSGGOG00000043866.1|UniProtKB=A0A2I2Z7W1 A0A2I2Z7W1 PTHR24060:SF26 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 8 transmembrane signaling receptor activity#GO:0004888;glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 GORGO|Ensembl=ENSGGOG00000015278.3|UniProtKB=G3RGZ0 G3RGZ0 BST2 PTHR15190:SF1 BONE MARROW STROMAL ANTIGEN 2 BONE MARROW STROMAL ANTIGEN 2 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 innate immune response#GO:0045087;response to virus#GO:0009615;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;defense response to virus#GO:0051607;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955 plasma membrane region#GO:0098590;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;cell periphery#GO:0071944;apical part of cell#GO:0045177 GORGO|Ensembl=ENSGGOG00000003672.3|UniProtKB=G3QM77 G3QM77 PTHR21109:SF10 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S21 MITOCHONDRIAL RIBOSOMAL PROTEIN S21 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000009733.3|UniProtKB=A0A2I2YF25 A0A2I2YF25 SEPTIN6 PTHR18884:SF55 SEPTIN SEPTIN-6 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402 cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000001980.3|UniProtKB=A0A2I2ZNN4 A0A2I2ZNN4 TXNRD2 PTHR48105:SF21 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN REDUCTASE 2, MITOCHONDRIAL antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000026997.2|UniProtKB=G3SKC3 G3SKC3 LOC101152035 PTHR11571:SF262 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE A2 glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;response to stimulus#GO:0050896;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;glutathione metabolic process#GO:0006749 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000008113.3|UniProtKB=G3QYJ4 G3QYJ4 SLC25A42 PTHR24089:SF736 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A42 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000004970.3|UniProtKB=G3QQK2 G3QQK2 TRIM44 PTHR24103:SF597 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 44 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 regulation of biological quality#GO:0065008;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;response to external stimulus#GO:0009605;protein stabilization#GO:0050821;regulation of gene expression#GO:0010468;defense response#GO:0006952;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of protein stability#GO:0031647;defense response to symbiont#GO:0140546;immune response#GO:0006955 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000000918.3|UniProtKB=G3RND8 G3RND8 MPRIP PTHR17271:SF9 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN MYOSIN PHOSPHATASE RHO-INTERACTING PROTEIN actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000013388.3|UniProtKB=G3RC37 G3RC37 WDR55 PTHR44156:SF5 SUPERNUMERARY LIMBS, ISOFORM B-RELATED WD REPEAT-CONTAINING PROTEIN 55 GORGO|Ensembl=ENSGGOG00000006804.3|UniProtKB=G3QV97 G3QV97 THYN1 PTHR14087:SF7 THYMOCYTE NUCLEAR PROTEIN 1 THYMOCYTE NUCLEAR PROTEIN 1 GORGO|Ensembl=ENSGGOG00000040310.1|UniProtKB=A0A2I2ZW35 A0A2I2ZW35 PTHR19343:SF15 T CELL RECEPTOR ALPHA VARIABLE 1-2 IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000011593.3|UniProtKB=G3R7H7 G3R7H7 DDR2 PTHR24416:SF295 TYROSINE-PROTEIN KINASE RECEPTOR DISCOIDIN DOMAIN-CONTAINING RECEPTOR 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;binding#GO:0005488;collagen binding#GO:0005518;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of intracellular signal transduction#GO:1902533;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000039028.1|UniProtKB=A0A2I2ZDZ5 A0A2I2ZDZ5 PTHR23266:SF419 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA-LIKE POLYPEPTIDE 1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000011963.3|UniProtKB=G3SBN6 G3SBN6 MRM2 PTHR10920:SF18 RIBOSOMAL RNA METHYLTRANSFERASE RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;O-methyltransferase activity#GO:0008171;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;methylation#GO:0032259;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;rRNA modification#GO:0000154;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000023154.2|UniProtKB=G3S8J8 G3S8J8 TENT2 PTHR12271:SF140 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE GLD2 catalytic activity, acting on RNA#GO:0140098;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA destabilization#GO:0061157;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;mRNA processing#GO:0006397;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396 nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000000287.3|UniProtKB=G3QDG4 G3QDG4 SLC4A9 PTHR11453:SF52 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 4 monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;bicarbonate transmembrane transporter activity#GO:0015106;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000011013.3|UniProtKB=G3R5Z8 G3R5Z8 ASXL2 PTHR13578:SF11 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL2-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;chromatin binding#GO:0003682;protein binding#GO:0005515 positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;PcG protein complex#GO:0031519 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000034818.2|UniProtKB=G3SKQ5 G3SKQ5 SHQ1 PTHR12967:SF0 PROTEIN SHQ1 HOMOLOG PROTEIN SHQ1 HOMOLOG cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-RNA complex assembly#GO:0022618;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000016082.3|UniProtKB=G3RJ13 G3RJ13 FAM167A PTHR32289:SF3 PROTEIN FAM167A PROTEIN FAM167A GORGO|Ensembl=ENSGGOG00000000720.3|UniProtKB=G3QEL1 G3QEL1 LOC101148806 PTHR23262:SF245 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 26-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000010872.3|UniProtKB=G3R5M3 G3R5M3 MLLT1 PTHR47827:SF4 AHD DOMAIN-CONTAINING PROTEIN PROTEIN ENL binding#GO:0005488;chromatin binding#GO:0003682 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000005327.3|UniProtKB=G3S6C5 G3S6C5 PTHR15283:SF3 GREMLIN 1 GREMLIN-1 binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine binding#GO:0019955;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000026661.2|UniProtKB=G3SBP9 G3SBP9 PLAG1 PTHR24390:SF180 ZINC FINGER PROTEIN ZINC FINGER PROTEIN PLAG1 double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022020.2|UniProtKB=G3RS71 G3RS71 LOC101151151 PTHR48026:SF32 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN RRM DOMAIN-CONTAINING PROTEIN mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000021975.2|UniProtKB=G3RGQ1 G3RGQ1 LOC101136905 PTHR22799:SF7 TETRANECTIN-RELATED 35 KDA PULMONARY SURFACTANT-ASSOCIATED PROTEIN multicellular organismal process#GO:0032501;ossification#GO:0001503 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000010029.3|UniProtKB=A0A2I2Y4G9 A0A2I2Y4G9 IDH3B PTHR11835:SF84 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;tricarboxylic acid cycle#GO:0006099;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;generation of precursor metabolites and energy#GO:0006091 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000024675.2|UniProtKB=G3SDL7 G3SDL7 LOC101140560 PTHR15425:SF0 CD160 ANTIGEN CD160 ANTIGEN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000037356.1|UniProtKB=A0A2I2Z1K9 A0A2I2Z1K9 PTP4A3 PTHR23339:SF119 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 3 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870;endothelial cell migration#GO:0043542 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011293.3|UniProtKB=G3R6P5 G3R6P5 QNG1 PTHR21314:SF0 QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 GORGO|Ensembl=ENSGGOG00000041852.1|UniProtKB=A0A2I2YZE2 A0A2I2YZE2 SDC1 PTHR10915:SF5 SYNDECAN SYNDECAN-1 regulation of organelle organization#GO:0033043;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of cellular component biogenesis#GO:0044089;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012414.3|UniProtKB=A0A2K5TIY0 A0A2K5TIY0 CAMP PTHR10206:SF2 CATHELICIDIN CATHELICIDIN ANTIMICROBIAL PEPTIDE carbohydrate derivative binding#GO:0097367;binding#GO:0005488;lipopolysaccharide binding#GO:0001530;lipid binding#GO:0008289 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000026914.2|UniProtKB=G3SDB0 G3SDB0 WDR36 PTHR22840:SF12 WD REPEAT-CONTAINING PROTEIN 36 WD REPEAT-CONTAINING PROTEIN 36 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000014556.3|UniProtKB=A0A2I2ZKJ0 A0A2I2ZKJ0 MAP3K19 PTHR48011:SF4 CCR4-NOT TRANSCRIPTIONAL COMPLEX SUBUNIT CAF120-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000022366.2|UniProtKB=A0A2I2Z6I4 A0A2I2Z6I4 DHFR PTHR48069:SF6 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;reductase#PC00198 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948 GORGO|Ensembl=ENSGGOG00000014767.3|UniProtKB=A0A2I2YQ03 A0A2I2YQ03 SLC25A45 PTHR45624:SF6 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED METHYLATED AMINO-ACID TRANSPORTER SLC25A45 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004967.3|UniProtKB=A0A2I2YHR1 A0A2I2YHR1 ARID1A PTHR12656:SF12 BRG-1 ASSOCIATED FACTOR 250 BAF250 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1A chromatin binding#GO:0003682;binding#GO:0005488;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000037928.1|UniProtKB=A0A2I2YBD3 A0A2I2YBD3 PTHR24390:SF276 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZFP2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007574.3|UniProtKB=G3QX77 G3QX77 PEAK3 PTHR22972:SF6 SERINE/THREONINE PROTEIN KINASE PROTEIN PEAK3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;focal adhesion#GO:0005925;intracellular membraneless organelle#GO:0043232;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007516.3|UniProtKB=G3SIV6 G3SIV6 SLCO4A1 PTHR11388:SF164 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4A1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013688.3|UniProtKB=G3RCW6 G3RCW6 AGFG2 PTHR46134:SF4 DRONGO, ISOFORM F ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 2 male gamete generation#GO:0048232;cellular developmental process#GO:0048869;nucleus organization#GO:0006997;developmental process#GO:0032502;spermatogenesis#GO:0007283;reproductive process#GO:0022414;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;supramolecular fiber organization#GO:0097435;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatid development#GO:0007286;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;cytoskeleton organization#GO:0007010;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;vesicle organization#GO:0016050;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;gamete generation#GO:0007276;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;acrosome assembly#GO:0001675;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;spermatid differentiation#GO:0048515 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000023684.2|UniProtKB=G3RNH1 G3RNH1 HOXC12 PTHR46440:SF2 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-C12 DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000005490.3|UniProtKB=G3QRW2 G3QRW2 KCNN4 PTHR10153:SF41 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL INTERMEDIATE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 4 ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium-activated potassium channel activity#GO:0015269;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;binding#GO:0005488;gated channel activity#GO:0022836;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;calmodulin binding#GO:0005516;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;neuronal cell body#GO:0043025;membrane#GO:0016020;cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000012603.3|UniProtKB=G3RA38 G3RA38 PACRGL PTHR21207:SF1 PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED PACRG-LIKE PROTEIN GORGO|Ensembl=ENSGGOG00000000237.3|UniProtKB=G3QDC3 G3QDC3 BCO1 PTHR10543:SF132 BETA-CAROTENE DIOXYGENASE BETA,BETA-CAROTENE 15,15'-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;terpenoid metabolic process#GO:0006721;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;isoprenoid metabolic process#GO:0006720;retinoid metabolic process#GO:0001523 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000011580.3|UniProtKB=A0A2I2YSI8 A0A2I2YSI8 BAZ2A PTHR45915:SF5 TRANSCRIPTION INTERMEDIARY FACTOR BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin-protein adaptor activity#GO:0140463 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000015814.3|UniProtKB=A0A2I2YTJ4 A0A2I2YTJ4 PSMA3 PTHR11599:SF10 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-3 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;proteasome complex#GO:0000502;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000016020.3|UniProtKB=A0A2I2ZGC4 A0A2I2ZGC4 SAYSD1 PTHR13527:SF0 SAYSVFN DOMAIN-CONTAINING PROTEIN 1 SAYSVFN DOMAIN-CONTAINING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule catabolic process#GO:0009057;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rescue of stalled cytosolic ribosome#GO:0072344;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cytoplasmic translation#GO:0002181;translation#GO:0006412;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000042148.1|UniProtKB=A0A2I2YIX9 A0A2I2YIX9 GNG12 PTHR13809:SF9 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-12 ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;catalytic complex#GO:1902494;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;membrane protein complex#GO:0098796 heterotrimeric G-protein#PC00117 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430 GORGO|Ensembl=ENSGGOG00000037322.1|UniProtKB=A0A2I2ZCC1 A0A2I2ZCC1 PTHR10394:SF40 40S RIBOSOMAL PROTEIN S8 40S RIBOSOMAL PROTEIN S8 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000011382.3|UniProtKB=G3R6Y1 G3R6Y1 USP54 PTHR22975:SF5 UBIQUITIN SPECIFIC PROTEINASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 54 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000009437.3|UniProtKB=G3R1Y3 G3R1Y3 PTHR15427:SF41 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q AND TUMOR NECROSIS FACTOR-RELATED PROTEIN 9B receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;lipid oxidation#GO:0034440;lipid modification#GO:0030258 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010761.3|UniProtKB=G3R5C0 G3R5C0 PTHR36683:SF2 CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1 CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1 central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;anatomical structure formation involved in morphogenesis#GO:0048646;cellular process#GO:0009987;cell migration#GO:0016477;multicellular organismal process#GO:0032501;brain development#GO:0007420;developmental maturation#GO:0021700;nervous system development#GO:0007399;head development#GO:0060322;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;anatomical structure maturation#GO:0071695;anatomical structure morphogenesis#GO:0009653;cell motility#GO:0048870;central nervous system development#GO:0007417;cell differentiation#GO:0030154 GORGO|Ensembl=ENSGGOG00000027060.2|UniProtKB=A0A2I2ZX63 A0A2I2ZX63 AP1S1 PTHR11753:SF14 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-1A vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000022324.2|UniProtKB=G3S5W5 G3S5W5 CCDC116 PTHR36861:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 116 COILED-COIL DOMAIN-CONTAINING PROTEIN 116 GORGO|Ensembl=ENSGGOG00000004144.3|UniProtKB=G3QNF4 G3QNF4 ILF3 PTHR45762:SF4 ZINC FINGER RNA-BINDING PROTEIN INTERLEUKIN ENHANCER-BINDING FACTOR 3 RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000026207.2|UniProtKB=G3SFR6 G3SFR6 PTHR10877:SF185 POLYCYSTIN FAMILY MEMBER POLYCYSTIN FAMILY RECEPTOR FOR EGG JELLY metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to mechanical stimulus#GO:0009612;detection of stimulus#GO:0051606;detection of mechanical stimulus#GO:0050982;response to abiotic stimulus#GO:0009628 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000002252.4|UniProtKB=G3QIK5 G3QIK5 ZNF131 PTHR24409:SF324 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 131 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007870.3|UniProtKB=G3RMF5 G3RMF5 PTHR10183:SF382 CALPAIN CALPAIN-15 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000006403.3|UniProtKB=G3QU69 G3QU69 DOLPP1 PTHR11247:SF82 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 DOLICHYLDIPHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008584.3|UniProtKB=A0A2I2Y8S4 A0A2I2Y8S4 PTHR24028:SF254 CADHERIN-87A PROTOCADHERIN-11 X-LINKED-RELATED cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000016740.3|UniProtKB=G3RKQ2 G3RKQ2 TSPYL1 PTHR11875:SF108 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 1 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000011242.3|UniProtKB=G3R6K6 G3R6K6 SUFU PTHR10928:SF2 SUPPRESSOR OF FUSED SUPPRESSOR OF FUSED HOMOLOG protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Hedgehog signaling pathway#P00025>Su(fu)#P00699 GORGO|Ensembl=ENSGGOG00000001046.3|UniProtKB=G3QFF8 G3QFF8 CSF2 PTHR10059:SF0 GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR GM-CSF GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;hemopoiesis#GO:0030097;cell development#GO:0048468;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000028377.2|UniProtKB=G3RQ51 G3RQ51 PTHR11819:SF112 SOLUTE CARRIER FAMILY 5 GLUCOSE SENSOR PROTEIN SLC5A4-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;carbohydrate transport#GO:0008643;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;renal absorption#GO:0070293;system process#GO:0003008;cellular process#GO:0009987;renal system process#GO:0003014;D-glucose transmembrane transport#GO:1904659;carbohydrate transmembrane transport#GO:0034219;multicellular organismal process#GO:0032501;import across plasma membrane#GO:0098739 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000017036.3|UniProtKB=G3RLH7 G3RLH7 POMK PTHR22618:SF2 PROTEIN O-MANNOSE KINASE PROTEIN O-MANNOSE KINASE carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000022837.2|UniProtKB=A0A2I2ZV95 A0A2I2ZV95 HACD3 PTHR11035:SF20 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 3 hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000043036.1|UniProtKB=A0A2I2YQ59 A0A2I2YQ59 PTHR14564:SF5 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000022968.2|UniProtKB=A0A2I2YK03 A0A2I2YK03 PTHR47448:SF4 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN MITOGEN-ACTIVATED PROTEIN KINASE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000028054.2|UniProtKB=G3RSH1 G3RSH1 MINDY4 PTHR12473:SF8 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED GORGO|Ensembl=ENSGGOG00000024156.2|UniProtKB=G3SGQ2 G3SGQ2 SPINK5 PTHR10913:SF71 FOLLISTATIN-RELATED SERINE PROTEASE INHIBITOR KAZAL-TYPE 5 serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 cellular process#GO:0009987;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell differentiation#GO:0030154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000028063.2|UniProtKB=G3SDY5 G3SDY5 PTHR48637:SF1 SECRETED PROTEIN-RELATED CHROMOSOME 14 OPEN READING FRAME 178 GORGO|Ensembl=ENSGGOG00000002257.3|UniProtKB=A0A2I2ZPK6 A0A2I2ZPK6 PTHR46052:SF3 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN 9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Phosducin#P00758 GORGO|Ensembl=ENSGGOG00000011712.3|UniProtKB=G3R7U3 G3R7U3 LOC101128796 PTHR45589:SF6 WD REPEAT DOMAIN 62, ISOFORM G MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1 regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789 microtubule cytoskeleton#GO:0015630;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000010204.3|UniProtKB=G3R3X0 G3R3X0 LRRC69 PTHR45752:SF1 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 69 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009902.3|UniProtKB=G3R371 G3R371 PTHR21610:SF9 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000000084.3|UniProtKB=G3QCY3 G3QCY3 DAPK1 PTHR24347:SF442 SERINE/THREONINE-PROTEIN KINASE DEATH-ASSOCIATED PROTEIN KINASE 1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000043422.1|UniProtKB=A0A2I2Z0P8 A0A2I2Z0P8 PTHR14207:SF3 STEROL ISOMERASE EXPERA DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000002581.3|UniProtKB=G3QJE8 G3QJE8 NODAL PTHR11848:SF159 TGF-BETA FAMILY NODAL HOMOLOG signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;activin receptor signaling pathway#GO:0032924;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000027174.2|UniProtKB=G3RZ17 G3RZ17 LOC101141440 PTHR22879:SF14 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 2A-RELATED GORGO|Ensembl=ENSGGOG00000014786.3|UniProtKB=G3RFQ8 G3RFQ8 AP1G2 PTHR22780:SF28 ADAPTIN, ALPHA/GAMMA/EPSILON AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;Golgi to endosome transport#GO:0006895;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;clathrin vesicle coat#GO:0030125;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;coated membrane#GO:0048475;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane coat#GO:0030117 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000008939.3|UniProtKB=G3R0P6 G3R0P6 SLC25A12 PTHR12294:SF1 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 mitochondrial calcium ion homeostasis#GO:0051560;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial protein-containing complex#GO:0098798;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;transporter complex#GO:1990351;inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000006063.3|UniProtKB=G3QTC1 G3QTC1 FAXDC2 PTHR11863:SF241 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;primary metabolic process#GO:0044238;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000013155.3|UniProtKB=G3RBH6 G3RBH6 CLTA PTHR10639:SF1 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN A binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515 receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583 transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle coat#GO:0030120;secretory vesicle#GO:0099503;presynapse#GO:0098793;clathrin-coated vesicle membrane#GO:0030665;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;clathrin vesicle coat#GO:0030125;clathrin coat#GO:0030118;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;coated membrane#GO:0048475;coated vesicle#GO:0030135;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Huntington disease#P00029>Clathrin#P00798 GORGO|Ensembl=ENSGGOG00000015643.3|UniProtKB=G3RHY2 G3RHY2 SIKE1 PTHR12186:SF4 SIKE FAMILY MEMBER SUPPRESSOR OF IKBKE 1 GORGO|Ensembl=ENSGGOG00000009836.3|UniProtKB=G3R2Z1 G3R2Z1 PTHR23299:SF51 METALLOTHIONEIN METALLOTHIONEIN-1B cation binding#GO:0043169;metal ion binding#GO:0046872;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 detoxification#GO:0098754;response to chemical#GO:0042221;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;detoxification of inorganic compound#GO:0061687;response to stress#GO:0006950;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;response to metal ion#GO:0010038;response to cadmium ion#GO:0046686;homeostatic process#GO:0042592;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion homeostasis#GO:0098771;cellular response to chemical stimulus#GO:0070887 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000012667.3|UniProtKB=A0A2I2ZYI7 A0A2I2ZYI7 LRRC46 PTHR45973:SF9 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000037312.1|UniProtKB=A0A2I2YJY5 A0A2I2YJY5 PTHR22812:SF134 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 3 chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000001912.3|UniProtKB=G3QHQ0 G3QHQ0 PTHR22802:SF394 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR 2 binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000023482.2|UniProtKB=G3RQX4 G3RQX4 MIEN1 PTHR15124:SF27 SELENOPROTEIN W MIGRATION AND INVASION ENHANCER 1 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of filopodium assembly#GO:0051489;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of apoptotic process#GO:0042981;positive regulation of cellular component biogenesis#GO:0044089;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;regulation of cell projection assembly#GO:0060491;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014152.3|UniProtKB=A0A2I2Y9L6 A0A2I2Y9L6 STIM1 PTHR15136:SF9 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE 1 cation binding#GO:0043169;channel regulator activity#GO:0016247;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;transporter regulator activity#GO:0141108;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106 monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000009086.3|UniProtKB=A0A2I2YBT2 A0A2I2YBT2 NMNAT1 PTHR12039:SF21 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 1 nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 nucleotidyltransferase#PC00174;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000008084.3|UniProtKB=G3RZ07 G3RZ07 ARHGAP8 PTHR45808:SF4 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 8 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 VEGF signaling pathway#P00056>Rac#P01421;PDGF signaling pathway#P00047>Rho#P01174;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520;Angiogenesis#P00005>Rac#P00245 GORGO|Ensembl=ENSGGOG00000006505.3|UniProtKB=G3QUG8 G3QUG8 MEGF10 PTHR24035:SF136 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 10 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular process#GO:0009987;cellular component organization#GO:0016043;membrane organization#GO:0061024;cell migration#GO:0016477;endocytosis#GO:0006897;cell motility#GO:0048870;transport#GO:0006810;membrane invagination#GO:0010324;phagocytosis#GO:0006909;establishment of localization#GO:0051234;import into cell#GO:0098657;phagocytosis, engulfment#GO:0006911;localization#GO:0051179;apoptotic cell clearance#GO:0043277;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000013421.3|UniProtKB=A0A2I2YCG1 A0A2I2YCG1 ACTA2 PTHR11937:SF445 ACTIN ACTIN, AORTIC SMOOTH MUSCLE structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944 GORGO|Ensembl=ENSGGOG00000009786.3|UniProtKB=G3R2U9 G3R2U9 TP53 PTHR11447:SF6 CELLULAR TUMOR ANTIGEN P53 CELLULAR TUMOR ANTIGEN P53 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110 regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;signaling#GO:0023052;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;intrinsic apoptotic signaling pathway#GO:0097193;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 P53-like transcription factor#PC00253;gene-specific transcriptional regulator#PC00264 p53 pathway feedback loops 2#P04398>p53#P04668;Wnt signaling pathway#P00057>p53#P01430;Huntington disease#P00029>p53#P00797;p53 pathway#P00059>p53#P01485;p53 pathway by glucose deprivation#P04397>p53#P04640;P53 pathway feedback loops 1#P04392>p53#P04539;Apoptosis signaling pathway#P00006>p53#P00273;p53 pathway#P00059>p53#G04702 GORGO|Ensembl=ENSGGOG00000041245.1|UniProtKB=A0A2I2YR49 A0A2I2YR49 IGF2 PTHR46886:SF1 INSULIN-LIKE GROWTH FACTOR II INSULIN-LIKE GROWTH FACTOR 2 intercellular signal molecule#PC00207;growth factor#PC00112 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896 GORGO|Ensembl=ENSGGOG00000024609.2|UniProtKB=G3SB85 G3SB85 EIF2S3 PTHR42854:SF19 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED tRNA binding#GO:0000049;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723;translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676 translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000001454.3|UniProtKB=G3QGJ2 G3QGJ2 DNAH2 PTHR10676:SF183 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 2 catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777 cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cell motility#GO:0048870;microtubule-based movement#GO:0007018 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;dynein complex#GO:0030286;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000000067.3|UniProtKB=G3QCW5 G3QCW5 PTHR10052:SF55 60S RIBOSOMAL PROTEIN L18A 60S RIBOSOMAL PROTEIN L18A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000015407.3|UniProtKB=G3RHC0 G3RHC0 ITGA10 PTHR23220:SF26 INTEGRIN ALPHA INTEGRIN ALPHA-10 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell surface receptor signaling pathway#GO:0007166;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;signaling receptor complex#GO:0043235;integrin complex#GO:0008305 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000028016.2|UniProtKB=A0A2I2YDM5 A0A2I2YDM5 AGL PTHR10569:SF2 GLYCOGEN DEBRANCHING ENZYME GLYCOGEN DEBRANCHING ENZYME hydrolase activity#GO:0016787;glucosidase activity#GO:0015926;glycosyltransferase activity#GO:0016757;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;energy reserve metabolic process#GO:0006112;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;glycogen catabolic process#GO:0005980;generation of precursor metabolites and energy#GO:0006091;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170 GORGO|Ensembl=ENSGGOG00000041392.1|UniProtKB=A0A2I2ZQZ8 A0A2I2ZQZ8 MPP2 PTHR23122:SF35 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 2 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000023924.1|UniProtKB=G3SHV8 G3SHV8 COX1 PTHR10422:SF18 CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 1 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;transporter complex#GO:1990351;catalytic complex#GO:1902494 oxidase#PC00175;oxidoreductase#PC00176 ATP synthesis#P02721>Cytochrome oxidase aa3#P02793 GORGO|Ensembl=ENSGGOG00000044219.1|UniProtKB=A0A2I2ZW40 A0A2I2ZW40 CD93 PTHR24034:SF217 EGF-LIKE DOMAIN-CONTAINING PROTEIN COMPLEMENT COMPONENT C1Q RECEPTOR extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000014079.3|UniProtKB=G3RDW7 G3RDW7 KCTD18 PTHR14499:SF4 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD18 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010050.3|UniProtKB=G3SHF4 G3SHF4 ANKLE2 PTHR12349:SF4 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899 mitotic cell cycle#GO:0000278;membrane assembly#GO:0071709;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;organelle fission#GO:0048285;nuclear division#GO:0000280;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component assembly#GO:0022607;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitotic cell cycle process#GO:1903047;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000013475.3|UniProtKB=G3RCD8 G3RCD8 ATG2B PTHR13190:SF20 AUTOPHAGY-RELATED 2, ISOFORM A AUTOPHAGY-RELATED PROTEIN 2 HOMOLOG B phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;lipid binding#GO:0008289;protein-membrane adaptor activity#GO:0043495 macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;reticulophagy#GO:0061709;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;piecemeal microautophagy of the nucleus#GO:0034727;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;vacuole organization#GO:0007033;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;phagophore assembly site#GO:0000407 GORGO|Ensembl=ENSGGOG00000025239.2|UniProtKB=G3S3P3 G3S3P3 TBC1D19 PTHR16110:SF1 TBC1 DOMAIN FAMILY MEMBER 19 TBC1 DOMAIN FAMILY MEMBER 19 GORGO|Ensembl=ENSGGOG00000024447.2|UniProtKB=G3S9N3 G3S9N3 PTHR23087:SF13 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-17 chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008728.3|UniProtKB=G3S7U2 G3S7U2 CFAP57 PTHR32215:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000013736.3|UniProtKB=G3RD02 G3RD02 STC2 PTHR11245:SF2 STANNIOCALCIN STANNIOCALCIN-2 homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000006533.3|UniProtKB=G3QUJ0 G3QUJ0 UBL7 PTHR10677:SF25 UBIQUILIN UBIQUITIN-LIKE PROTEIN 7 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005446.3|UniProtKB=A0A2I2YIK7 A0A2I2YIK7 MEIS1 PTHR11850:SF126 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 multicellular organism development#GO:0007275;animal organ development#GO:0048513;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790;head development#GO:0060322;nervous system development#GO:0007399;embryonic pattern specification#GO:0009880;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;angiogenesis#GO:0001525;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell development#GO:0048468;positive regulation of cell population proliferation#GO:0008284;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;hemopoiesis#GO:0030097;tube development#GO:0035295;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000008974.3|UniProtKB=G3SIL0 G3SIL0 PTHR22906:SF52 PROPERDIN ADHESION G PROTEIN-COUPLED RECEPTOR B1 GORGO|Ensembl=ENSGGOG00000004411.3|UniProtKB=G3QP44 G3QP44 ATAD3A PTHR23075:SF5 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3A cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000012795.3|UniProtKB=G3RAK1 G3RAK1 LRIT1 PTHR24366:SF37 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT, IMMUNOGLOBULIN-LIKE AND TRANSMEMBRANE DOMAINS 1A immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000001936.3|UniProtKB=G3QHS2 G3QHS2 CAMK2N2 PTHR31007:SF1 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210 kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000009205.3|UniProtKB=G3R1D8 G3R1D8 CCNB3 PTHR10177:SF214 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B3 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000014387.3|UniProtKB=G3RER0 G3RER0 WNK2 PTHR13902:SF10 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK2 transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;protein serine/threonine kinase activity#GO:0004674;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096 regulation of localization#GO:0032879;regulation of transport#GO:0051049;chemical homeostasis#GO:0048878;regulation of monoatomic cation transmembrane transport#GO:1904062;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;monoatomic ion homeostasis#GO:0050801;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;homeostatic process#GO:0042592;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000007033.3|UniProtKB=G3QVU5 G3QVU5 TEKT5 PTHR19960:SF23 TEKTIN TEKTIN-5 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cilium assembly#GO:0060271;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000003962.3|UniProtKB=G3QMY9 G3QMY9 PTHR14319:SF7 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 POST-GPI ATTACHMENT TO PROTEINS FACTOR 6 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000025293.2|UniProtKB=G3S9V1 G3S9V1 ARPC4 PTHR22629:SF0 ARP2/3 COMPLEX 20 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 GORGO|Ensembl=ENSGGOG00000000107.3|UniProtKB=G3QD03 G3QD03 SLC6A7 PTHR11616:SF231 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT PROLINE TRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000002224.3|UniProtKB=G3QII1 G3QII1 CAB39 PTHR10182:SF11 CALCIUM-BINDING PROTEIN 39-RELATED CALCIUM-BINDING PROTEIN 39 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295 GORGO|Ensembl=ENSGGOG00000003565.3|UniProtKB=G3QLY2 G3QLY2 C19H5orf34 PTHR34531:SF1 ZGC:153352 CHROMOSOME 5 OPEN READING FRAME 34 GORGO|Ensembl=ENSGGOG00000013731.3|UniProtKB=A0A2I2YKJ4 A0A2I2YKJ4 CRMP1 PTHR11647:SF54 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;dihydropyrimidinase activity#GO:0004157 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339 GORGO|Ensembl=ENSGGOG00000016023.3|UniProtKB=G3RIW7 G3RIW7 PNLIP PTHR11610:SF147 LIPASE PANCREATIC TRIACYLGLYCEROL LIPASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000000743.3|UniProtKB=G3QEN6 G3QEN6 SCGN PTHR19972:SF15 CALBINDIN SECRETAGOGIN calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 cytosol#GO:0005829;nucleus#GO:0005634;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;axon terminus#GO:0043679;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;terminal bouton#GO:0043195;neuron projection terminus#GO:0044306;cell projection#GO:0042995;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000006633.3|UniProtKB=G3QUT1 G3QUT1 ZMAT4 PTHR46144:SF3 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER MATRIN-TYPE PROTEIN 4 GORGO|Ensembl=ENSGGOG00000013616.3|UniProtKB=G3RCP6 G3RCP6 PRSS8 PTHR24253:SF169 TRANSMEMBRANE PROTEASE SERINE PROSTASIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;gene expression#GO:0010467;protein maturation#GO:0051604;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of transport#GO:0051049;regulation of localization#GO:0032879;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of metal ion transport#GO:0010959;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;proteolysis#GO:0006508 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000011515.3|UniProtKB=G3R7A9 G3R7A9 USP32 PTHR21646:SF76 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 32 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 positive regulation of TOR signaling#GO:0032008;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of TORC1 signaling#GO:1903432;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of protein stability#GO:0031647;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;positive regulation of TORC1 signaling#GO:1904263 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000022096.2|UniProtKB=G3SCR8 G3SCR8 SFTPA1 PTHR22799:SF7 TETRANECTIN-RELATED 35 KDA PULMONARY SURFACTANT-ASSOCIATED PROTEIN multicellular organismal process#GO:0032501;ossification#GO:0001503 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000007741.3|UniProtKB=G3QXM3 G3QXM3 COG8 PTHR21311:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8 retrograde transport, vesicle recycling within Golgi#GO:0000301;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;localization#GO:0051179 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;COG complex#GO:0017119;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000034914.2|UniProtKB=A0A2I2ZHI9 A0A2I2ZHI9 AFF3 PTHR10528:SF16 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 3 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nervous system process#GO:0050877;nucleic acid biosynthetic process#GO:0141187;regulation of RNA metabolic process#GO:0051252;RNA metabolic process#GO:0016070;regulation of DNA-templated transcription#GO:0006355;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;DNA-templated transcription elongation#GO:0006354;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;gene expression#GO:0010467;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;system process#GO:0003008;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000001107.3|UniProtKB=G3QFL5 G3QFL5 ACO2 PTHR43160:SF3 ACONITATE HYDRATASE B ACONITATE HYDRATASE, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;catalytic activity#GO:0003824;iron-sulfur cluster binding#GO:0051536;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 cytosol#GO:0005829;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 lyase#PC00144;hydratase#PC00120 TCA cycle#P00051>Aconitase#P01268 GORGO|Ensembl=ENSGGOG00000009956.3|UniProtKB=G3R392 G3R392 PEX39 PTHR40657:SF1 HYPOTHETICAL PROTEIN LOC681367 PEROXISOMAL BIOGENESIS FACTOR 39 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031;peroxisomal transport#GO:0043574;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000004525.3|UniProtKB=G3QPF0 G3QPF0 HDAC6 PTHR10625:SF21 HISTONE DEACETYLASE HDAC1-RELATED PROTEIN DEACETYLASE HDAC6 catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacylase activity#GO:0160215;catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;histone modifying activity#GO:0140993;hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;neuron differentiation#GO:0030182;nervous system development#GO:0007399;biological regulation#GO:0065007;chromatin organization#GO:0006325;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 cytosol#GO:0005829;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000015681.3|UniProtKB=G3RI14 G3RI14 SCGB1D1 PTHR11332:SF5 SECRETOGLOBIN FAMILY 1D SECRETOGLOBIN FAMILY 1D MEMBER 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000042136.1|UniProtKB=A0A2I2Y724 A0A2I2Y724 PTHR10902:SF36 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;translation#GO:0006412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000038590.1|UniProtKB=A0A2I2Z5H9 A0A2I2Z5H9 MPC1 PTHR14154:SF8 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;intracellular transport#GO:0046907;carboxylic acid transport#GO:0046942;mitochondrial transmembrane transport#GO:1990542;organic acid transport#GO:0015849;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000022411.2|UniProtKB=G3RXM6 G3RXM6 PTHR18902:SF25 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000016473.3|UniProtKB=G3RK17 G3RK17 VDR PTHR24082:SF38 NUCLEAR HORMONE RECEPTOR VITAMIN D3 RECEPTOR lipid binding#GO:0008289;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;steroid binding#GO:0005496;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 Vitamin D metabolism and pathway#P04396>VDR#P04606 GORGO|Ensembl=ENSGGOG00000005107.3|UniProtKB=G3QQX3 G3QQX3 ZKSCAN1 PTHR23226:SF94 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006922.3|UniProtKB=A0A2I2YEN3 A0A2I2YEN3 RIMS2 PTHR12157:SF15 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular component organization#GO:0016043;regulation of vesicle-mediated transport#GO:0060627;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of neurotransmitter secretion#GO:0046928;regulation of synaptic vesicle exocytosis#GO:2000300;export from cell#GO:0140352;signaling#GO:0023052;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;cellular localization#GO:0051641;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;regulation of exocytosis#GO:0017157 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;membrane#GO:0016020;presynapse#GO:0098793;cell cortex#GO:0005938;cell periphery#GO:0071944;cell junction#GO:0030054;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;synaptic membrane#GO:0097060 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>RIM1alpha/2alpha#P05776 GORGO|Gene=LYZ|UniProtKB=P79179 P79179 LYZ PTHR11407:SF28 LYSOZYME C LYSOZYME C hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;lysozyme activity#GO:0003796;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 defense response#GO:0006952;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000010458.3|UniProtKB=G3R4J0 G3R4J0 C4H5orf46 PTHR37864:SF1 SIMILAR TO AVLV472 SIMILAR TO HUMAN CHROMOSOME 5 OPEN READING FRAME 46 GORGO|Ensembl=ENSGGOG00000011296.3|UniProtKB=G3SBT2 G3SBT2 RGMB PTHR31428:SF5 RGM DOMAIN FAMILY MEMBER DRAG-1 REPULSIVE GUIDANCE MOLECULE B coreceptor activity#GO:0015026;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015339.3|UniProtKB=G3RH54 G3RH54 PTHR10881:SF44 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 6A-RELATED Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 Golgi apparatus#GO:0005794;cis-Golgi network#GO:0005801;organelle membrane#GO:0031090;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;Golgi cis cisterna#GO:0000137;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi stack#GO:0005795;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015301.3|UniProtKB=G3RH09 G3RH09 GPN2 PTHR21231:SF3 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 2 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000014284.3|UniProtKB=A0A2I2YIY7 A0A2I2YIY7 PLOD2 PTHR10730:SF6 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023256.2|UniProtKB=G3RSC6 G3RSC6 SLCO4C1 PTHR11388:SF103 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4C1 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014563.3|UniProtKB=G3RF55 G3RF55 TUBGCP2 PTHR19302:SF13 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 2 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;organelle assembly#GO:0070925 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000006866.3|UniProtKB=G3QVF4 G3QVF4 ACTR10 PTHR11937:SF14 ACTIN ACTIN-RELATED PROTEIN 10 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 microtubule-based transport#GO:0099111;retrograde axonal transport#GO:0008090;axonal transport#GO:0098930;organelle localization#GO:0051640;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;transport#GO:0006810;intracellular transport#GO:0046907;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;axo-dendritic transport#GO:0008088;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000014900.3|UniProtKB=G3RG06 G3RG06 EGLN3 PTHR12907:SF28 EGL NINE HOMOLOG-RELATED PROLYL HYDROXYLASE EGLN3 catalytic activity#GO:0003824;ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;iron ion binding#GO:0005506;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;cation binding#GO:0043169 response to hypoxia#GO:0001666;regulation of apoptotic process#GO:0042981;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;regulation of programmed cell death#GO:0043067;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 GORGO|Ensembl=ENSGGOG00000024594.2|UniProtKB=A0A2I2YT16 A0A2I2YT16 PTHR18860:SF96 14-3-3 PROTEIN 14-3-3 DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000017110.3|UniProtKB=G3RXK2 G3RXK2 STAT3 PTHR11801:SF2 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;cellular response to stimulus#GO:0051716;interleukin-2-mediated signaling pathway#GO:0038110;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to peptide hormone stimulus#GO:0071375;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to peptide hormone#GO:0043434;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;response to endogenous stimulus#GO:0009719;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;response to hormone#GO:0009725;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway via STAT#GO:0097696;interleukin-9-mediated signaling pathway#GO:0038113 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Interleukin signaling pathway#P00036>STAT#P00996;CCKR signaling map#P06959>STAT3#P07165;Ras Pathway#P04393>Stat 1/3#P04566;Gonadotropin-releasing hormone receptor pathway#P06664>STAT3#P06795;PDGF signaling pathway#P00047>STAT#P01173;EGF receptor signaling pathway#P00018>STAT#P00561;Angiogenesis#P00005>STAT3#P00217;JAK/STAT signaling pathway#P00038>STAT#P01027;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832 GORGO|Ensembl=ENSGGOG00000013906.3|UniProtKB=G3RDG2 G3RDG2 CXHXorf38 PTHR35083:SF1 RGD1565685 PROTEIN RGD1565685 PROTEIN GORGO|Ensembl=ENSGGOG00000002403.3|UniProtKB=G3QIZ3 G3QIZ3 LOC101144292 PTHR13817:SF84 TITIN CONTACTIN-3 structural protein#PC00211 GORGO|Gene=BIRC8|UniProtKB=Q95M71 Q95M71 BIRC8 PTHR10044:SF167 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 8 aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;enzyme regulator activity#GO:0030234;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;regulation of protein modification process#GO:0031399;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of Wnt signaling pathway#GO:0030177;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell cycle#GO:0051726;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000023125.2|UniProtKB=G3S6H0 G3S6H0 ATP11B PTHR24092:SF57 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IF intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035 plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;recycling endosome#GO:0055037;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025080.2|UniProtKB=G3RMV2 G3RMV2 PTHR48034:SF9 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RRM DOMAIN-CONTAINING PROTEIN protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ribosomal large subunit binding#GO:0043023 macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of protein metabolic process#GO:0051246;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008515.3|UniProtKB=G3QZK8 G3QZK8 TM2D1 PTHR21016:SF1 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 apoptotic signaling pathway#GO:0097190;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of Notch signaling pathway#GO:0045747;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;cell death#GO:0008219;positive regulation of signal transduction#GO:0009967;programmed cell death#GO:0012501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000022955.2|UniProtKB=A0A2I2YTY5 A0A2I2YTY5 EIF3E PTHR10317:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;eukaryotic translation initiation factor 3 complex#GO:0005852 translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000008407.3|UniProtKB=G3QZA8 G3QZA8 PTHR24409:SF445 ZINC FINGER PROTEIN 142 TRANSCRIPTION FACTOR IIIA double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007360.3|UniProtKB=G3S0I7 G3S0I7 NFYC PTHR10252:SF91 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013333.3|UniProtKB=G3RBY8 G3RBY8 TMEM98 PTHR32510:SF4 TRANSMEMBRANE PROTEIN 98 TRANSMEMBRANE PROTEIN 98 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000000619.3|UniProtKB=G3QEB8 G3QEB8 EDNRA PTHR46099:SF2 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN-1 RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;system process#GO:0003008;cellular process#GO:0009987;developmental pigmentation#GO:0048066;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;pigmentation#GO:0043473;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 Endothelin signaling pathway#P00019>ET-RA/B#P00580 GORGO|Ensembl=ENSGGOG00000008828.3|UniProtKB=G3S350 G3S350 DENND11 PTHR31017:SF2 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED DENN DOMAIN-CONTAINING PROTEIN 11 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004594.3|UniProtKB=A0A2I2ZA85 A0A2I2ZA85 EXD1 PTHR46628:SF1 PIRNA BIOGENESIS PROTEIN EXD1 PIRNA BIOGENESIS PROTEIN EXD1 RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;piRNA processing#GO:0034587 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000015550.3|UniProtKB=G3RTK5 G3RTK5 SLC37A2 PTHR43184:SF9 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A2 active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;phosphate transmembrane transporter activity#GO:0005315 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;organophosphate ester transport#GO:0015748;phosphate ion transport#GO:0006817 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012100.3|UniProtKB=G3SCJ6 G3SCJ6 PTHR24027:SF79 CADHERIN-23 CADHERIN-2 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cell migration#GO:0016477;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cell motility#GO:0048870;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;system development#GO:0048731;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell-cell junction#GO:0005911;cell leading edge#GO:0031252;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;apical part of cell#GO:0045177;cell-cell contact zone#GO:0044291;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;intercalated disc#GO:0014704;intracellular anatomical structure#GO:0005622 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000027298.2|UniProtKB=G3S5Z8 G3S5Z8 BANF1 PTHR47507:SF7 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000003959.3|UniProtKB=A0A2I2ZDY8 A0A2I2ZDY8 UBA3 PTHR10953:SF6 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 GORGO|Ensembl=ENSGGOG00000006190.3|UniProtKB=G3RY16 G3RY16 PTHR16001:SF6 ANGEL WING family ECTO-NOX DISULFIDE-THIOL EXCHANGER 1 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000011431.3|UniProtKB=A1YFA7 A1YFA7 PQBP1 PTHR21737:SF3 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 POLYGLUTAMINE-BINDING PROTEIN 1 binding#GO:0005488;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005928.3|UniProtKB=G3RSI8 G3RSI8 FBXO30 PTHR15933:SF13 PROTEIN CBG16327 F-BOX ONLY PROTEIN 30 GORGO|Ensembl=ENSGGOG00000011020.3|UniProtKB=G3R618 G3R618 MYLK3 PTHR24347:SF394 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE 3 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;actomyosin structure organization#GO:0031032;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cellular process#GO:0009987;heart development#GO:0007507;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cardiac muscle cell differentiation#GO:0055007;cellular anatomical entity morphogenesis#GO:0032989;striated muscle tissue development#GO:0014706;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;cellular response to stimulus#GO:0051716;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cell communication#GO:0007154;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;system development#GO:0048731;muscle tissue development#GO:0060537;tissue development#GO:0009888;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;developmental process#GO:0032502;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877 GORGO|Ensembl=ENSGGOG00000001115.3|UniProtKB=G3QFM1 G3QFM1 SSTR3 PTHR24229:SF42 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 GORGO|Ensembl=ENSGGOG00000025218.2|UniProtKB=A0A2I2ZTS4 A0A2I2ZTS4 PMS1 PTHR10073:SF54 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL PMS1 PROTEIN HOMOLOG 1 DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520 primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;mismatch repair#GO:0006298;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000023547.2|UniProtKB=A0A2I2YBY5 A0A2I2YBY5 TBCA PTHR21500:SF3 TUBULIN-SPECIFIC CHAPERONE A TUBULIN-SPECIFIC CHAPERONE A protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000000471.3|UniProtKB=A0A2I2Y315 A0A2I2Y315 STX16 PTHR19957:SF83 SYNTAXIN SYNTAXIN-16 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641 membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 GORGO|Ensembl=ENSGGOG00000015667.3|UniProtKB=G3RI06 G3RI06 PPP1R16B PTHR24179:SF31 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 16B enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of angiogenesis#GO:0045765;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;developmental process#GO:0032502;endothelial cell differentiation#GO:0045446;regulation of response to stimulus#GO:0048583;regulation of vasculature development#GO:1901342;regulation of anatomical structure morphogenesis#GO:0022603;cellular developmental process#GO:0048869;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of multicellular organismal process#GO:0051239;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000007453.3|UniProtKB=G3RRB5 G3RRB5 TMED10 PTHR22811:SF183 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 10 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193 endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000001301.3|UniProtKB=G3QG33 G3QG33 NUDCD3 PTHR12356:SF19 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 3 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000011268.3|UniProtKB=G3R6N6 G3R6N6 FAM91A1 PTHR28441:SF4 PROTEIN FAM91A1 PROTEIN FAM91A1 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000005055.3|UniProtKB=G3QQS7 G3QQS7 SLC52A3 PTHR12929:SF4 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 vitamin transport#GO:0051180;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;nitrogen compound transport#GO:0071705 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000009240.3|UniProtKB=G3R1G4 G3R1G4 PIGK PTHR48067:SF1 GPI-ANCHOR TRANSAMIDASE GPI-ANCHOR TRANSAMIDASE hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;transferase activity#GO:0016740;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096 GPI anchored protein biosynthesis#GO:0180046;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;peptidase complex#GO:1905368;cytoplasm#GO:0005737;caspase complex#GO:0008303;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 GORGO|Ensembl=ENSGGOG00000023201.2|UniProtKB=G3QHY1 G3QHY1 LOC115930113 PTHR14224:SF112 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 11-RELATED ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul2-RING ubiquitin ligase complex#GO:0031462;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004816.3|UniProtKB=G3QQ60 G3QQ60 LOC101142101 PTHR24293:SF1 CYTOCHROME P450 FAMILY 46 SUBFAMILY A CHOLESTEROL 24-HYDROXYLASE tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 lipid catabolic process#GO:0016042;cellular process#GO:0009987;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;steroid metabolic process#GO:0008202;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;steroid catabolic process#GO:0006706;sterol metabolic process#GO:0016125 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000005147.3|UniProtKB=G3QR12 G3QR12 PTHR12112:SF12 BNIP - RELATED BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 2 programmed cell death#GO:0012501;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000036643.1|UniProtKB=G3SCX1 G3SCX1 RPSA PTHR11489:SF17 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2-RELATED structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;translation#GO:0006412;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003789.3|UniProtKB=G3QMI9 G3QMI9 VILL PTHR11977:SF30 VILLIN VILLIN-LIKE PROTEIN phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;phosphatidylinositol phosphate binding#GO:1901981;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289 regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of actin filament depolymerization#GO:0030834;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000036161.1|UniProtKB=A0A2I2ZT47 A0A2I2ZT47 LOC109025310 PTHR21713:SF3 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000002218.3|UniProtKB=G3QIH5 G3QIH5 HOXA6 PTHR45659:SF14 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000010756.3|UniProtKB=G3R5B9 G3R5B9 PTHR23064:SF31 TROPONIN CALMODULIN LIKE 6 skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;system process#GO:0003008;neuromuscular process#GO:0050905;muscle contraction#GO:0006936;nervous system process#GO:0050877 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000005469.3|UniProtKB=G3QRV0 G3QRV0 NNT PTHR10160:SF22 NAD(P) TRANSHYDROGENASE NAD(P) TRANSHYDROGENASE, MITOCHONDRIAL nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;purine nucleotide binding#GO:0017076 NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000014550.3|UniProtKB=G3RF40 G3RF40 ODAD2 PTHR46241:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 4 ARMC4 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 2 GORGO|Ensembl=ENSGGOG00000003379.3|UniProtKB=G3RPV1 G3RPV1 SPATA20 PTHR42899:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 GORGO|Ensembl=ENSGGOG00000000360.3|UniProtKB=G3QDN0 G3QDN0 JRKL PTHR19303:SF16 TRANSPOSON JERKY PROTEIN HOMOLOG-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000026683.2|UniProtKB=A0A2I2Z8L6 A0A2I2Z8L6 PTHR10388:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1 ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488;nucleic acid binding#GO:0003676;translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 ribonucleoprotein complex#GO:1990904;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000007248.3|UniProtKB=A0A2I2ZWR6 A0A2I2ZWR6 SENP5 PTHR12606:SF10 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 5 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190 GORGO|Ensembl=ENSGGOG00000004885.3|UniProtKB=G3QQC4 G3QQC4 CARTPT PTHR16655:SF0 COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT PROTEIN negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;response to nutrient levels#GO:0031667;regulation of bone remodeling#GO:0046850;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to starvation#GO:0042594;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of biological quality#GO:0065008;regulation of tissue remodeling#GO:0034103;G protein-coupled receptor signaling pathway#GO:0007186;regulation of bone resorption#GO:0045124;cellular response to stress#GO:0033554 extracellular region#GO:0005576;cell body#GO:0044297;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040140.1|UniProtKB=A0A2I2YIW8 A0A2I2YIW8 PTHR23267:SF407 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 2-14-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000007738.3|UniProtKB=G3QXM7 G3QXM7 TOGARAM2 PTHR21567:SF42 CLASP TOG ARRAY REGULATOR OF AXONEMAL MICROTUBULES PROTEIN 2 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;cilium#GO:0005929;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic microtubule#GO:0005881;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000005812.3|UniProtKB=G3QSP9 G3QSP9 ZNF398 PTHR24390:SF240 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005467.3|UniProtKB=G3QRU2 G3QRU2 ARRB2 PTHR11792:SF20 ARRESTIN BETA-ARRESTIN-2 G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 localization#GO:0051179;sensory perception#GO:0007600;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;positive regulation of signal transduction#GO:0009967;establishment of localization#GO:0051234;positive regulation of MAPK cascade#GO:0043410;system process#GO:0003008;receptor-mediated endocytosis#GO:0006898;negative regulation of cellular process#GO:0048523;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;transport#GO:0006810;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;nervous system process#GO:0050877;regulation of signaling#GO:0023051;endocytosis#GO:0006897;negative regulation of biological process#GO:0048519;sensory perception of pain#GO:0019233;regulation of biological process#GO:0050789;import into cell#GO:0098657;regulation of MAPK cascade#GO:0043408;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of signal transduction#GO:0009968;receptor internalization#GO:0031623;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR2#P05923;CCKR signaling map#P06959>Beta-arrestin-1/2#P07187;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723;Wnt signaling pathway#P00057>beta-arrestin#P01456;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880 GORGO|Ensembl=ENSGGOG00000028338.2|UniProtKB=G3S7K9 G3S7K9 NUDT16L1 PTHR31699:SF6 NUDIX T16 FAMILY MEMBER TUDOR-INTERACTING REPAIR REGULATOR PROTEIN nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;snoRNA binding#GO:0030515;catalytic activity#GO:0003824 catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000038395.1|UniProtKB=A0A2I2YNA7 A0A2I2YNA7 CCL16 PTHR12015:SF21 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 16 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000000188.3|UniProtKB=A0A2I2YUE7 A0A2I2YUE7 TAS2R42 PTHR11394:SF70 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 42 signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026166.2|UniProtKB=G3RVP5 G3RVP5 SLAMF7 PTHR12080:SF46 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;T cell activation#GO:0042110;cell communication#GO:0007154;cell activation#GO:0001775;immune system process#GO:0002376;biological regulation#GO:0065007;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000040099.1|UniProtKB=G3R376 G3R376 ZBTB9 PTHR46105:SF13 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 9 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024389.2|UniProtKB=G3RWL8 G3RWL8 REP15 PTHR36682:SF1 RAB15 EFFECTOR PROTEIN RAB15 EFFECTOR PROTEIN metal ion transport#GO:0030001;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;macromolecule metabolic process#GO:0043170;localization#GO:0051179;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;monoatomic ion transport#GO:0006811;metabolic process#GO:0008152;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;recycling endosome#GO:0055037;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506 GORGO|Ensembl=ENSGGOG00000015649.3|UniProtKB=G3RHY8 G3RHY8 C7H8orf48 PTHR35256:SF1 CHROMOSOME 8 OPEN READING FRAME 48 SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 48 GORGO|Ensembl=ENSGGOG00000015494.3|UniProtKB=G3S3K1 G3S3K1 MAP3K5 PTHR11584:SF332 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709 apoptotic signaling pathway#GO:0097190;p38MAPK cascade#GO:0038066;JNK cascade#GO:0007254;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;neuron apoptotic process#GO:0051402;MAPK cascade#GO:0000165;intrinsic apoptotic signaling pathway#GO:0097193;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;signaling#GO:0023052;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716 non-receptor serine/threonine protein kinase#PC00167 p38 MAPK pathway#P05918>ASK1#P06043;Integrin signalling pathway#P00034>ERK#P00907;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Apoptosis signaling pathway#P00006>ASK1#P00272;FGF signaling pathway#P00021>MEKK1-5#P00634;FAS signaling pathway#P00020>ASK1#P00614;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 GORGO|Ensembl=ENSGGOG00000013779.3|UniProtKB=G3RD39 G3RD39 OR1L3 PTHR26453:SF626 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014593.3|UniProtKB=A0A2I2ZW48 A0A2I2ZW48 PTMS PTHR22745:SF3 PROTHYMOSIN ALPHA PARATHYMOSIN binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of apoptotic process#GO:0043066;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of apoptotic process#GO:0042981;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000012567.3|UniProtKB=A0A2I2YUT6 A0A2I2YUT6 BCL3 PTHR24118:SF51 POTE ANKYRIN DOMAIN B-CELL LYMPHOMA 3 PROTEIN transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 membrane traffic protein#PC00150 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859 GORGO|Ensembl=ENSGGOG00000034908.2|UniProtKB=A0A2I2Z8M8 A0A2I2Z8M8 DLG2 PTHR23119:SF6 DISCS LARGE DISKS LARGE HOMOLOG 2 structural molecule activity#GO:0005198;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;structural constituent of synapse#GO:0098918 macromolecule localization#GO:0033036;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;developmental process#GO:0032502;intracellular protein localization#GO:0008104;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;establishment or maintenance of apical/basal cell polarity#GO:0035088;trans-synaptic signaling#GO:0099537;protein localization to cell junction#GO:1902414;establishment or maintenance of bipolar cell polarity#GO:0061245;localization within membrane#GO:0051668;anatomical structure development#GO:0048856;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;cell communication#GO:0007154;system development#GO:0048731;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;cell adhesion#GO:0007155;receptor clustering#GO:0043113;cellular localization#GO:0051641;regulation of biological quality#GO:0065008 organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054;neuromuscular junction#GO:0031594;synaptic membrane#GO:0097060 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025284.2|UniProtKB=G3SHE6 G3SHE6 PRPH PTHR45652:SF14 GLIAL FIBRILLARY ACIDIC PROTEIN PERIPHERIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435 intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 intermediate filament#PC00129;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000028196.2|UniProtKB=G3RDK5 G3RDK5 LOC101124665 PTHR24327:SF72 HOMEOBOX PROTEIN HOMEOBOX PROTEIN NANOG RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;maintenance of cell number#GO:0098727;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;stem cell population maintenance#GO:0019827;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000040252.1|UniProtKB=A0A2I2ZXV1 A0A2I2ZXV1 PTHR11875:SF112 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1 LIKE 1 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000006300.3|UniProtKB=G3QTY0 G3QTY0 RANBP3 PTHR23138:SF91 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011083.3|UniProtKB=G3R667 G3R667 RANGRF PTHR15837:SF6 RAN GUANINE NUCLEOTIDE RELEASE FACTOR RAN GUANINE NUCLEOTIDE RELEASE FACTOR enzyme binding#GO:0019899;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;channel regulator activity#GO:0016247;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 biological regulation#GO:0065007;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heart process#GO:0003015;system process#GO:0003008;heart contraction#GO:0060047;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;circulatory system process#GO:0003013 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000009218.3|UniProtKB=G3S530 G3S530 TBC1D31 PTHR19853:SF1 WD REPEAT CONTAINING PROTEIN 3 WDR3 TBC1 DOMAIN FAMILY MEMBER 31 cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000004188.3|UniProtKB=G3QNJ2 G3QNJ2 TEX28 PTHR17613:SF10 CEREBRAL PROTEIN-11-RELATED TESTIS-SPECIFIC PROTEIN TEX28 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015482.3|UniProtKB=G3RHI7 G3RHI7 EML2 PTHR13720:SF50 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000025065.2|UniProtKB=G3SER6 G3SER6 ZBTB20 PTHR24399:SF19 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 20 DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000005051.3|UniProtKB=G3QQS9 G3QQS9 PIGN PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;protein maturation#GO:0051604;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000009027.3|UniProtKB=G3R0X7 G3R0X7 CD300LG PTHR11860:SF62 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 9 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000008056.3|UniProtKB=A0A2I2YYV6 A0A2I2YYV6 ZCCHC13 PTHR23002:SF53 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 13 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of translation#GO:0045727;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010715.3|UniProtKB=G3RQ86 G3RQ86 TRIM22 PTHR24103:SF650 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM22 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;kinase binding#GO:0019900;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;ubiquitin-like protein transferase activity#GO:0019787 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;positive regulation of autophagy#GO:0010508;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;defense response to other organism#GO:0098542;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of localization#GO:0032879;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;regulation of protein localization#GO:0032880;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of catabolic process#GO:0009896;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009062.3|UniProtKB=G3S8Z0 G3S8Z0 TPRKB PTHR15840:SF10 CGI-121 FAMILY MEMBER EKC_KEOPS COMPLEX SUBUNIT TPRKB nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000042825.1|UniProtKB=A0A2I2ZEF6 A0A2I2ZEF6 PLCXD3 PTHR13593:SF33 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 3 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000012026.3|UniProtKB=G3R8M4 G3R8M4 STXBP4 PTHR19964:SF16 MULTIPLE PDZ DOMAIN PROTEIN SYNTAXIN-BINDING PROTEIN 4 protein binding#GO:0005515;syntaxin binding#GO:0019905;SNARE binding#GO:0000149;binding#GO:0005488 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;response to hormone#GO:0009725;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003833.3|UniProtKB=G3QMM2 G3QMM2 MBD5 PTHR16112:SF18 METHYL-CPG BINDING PROTEIN, DROSOPHILA METHYL-CPG-BINDING DOMAIN PROTEIN 5 binding#GO:0005488;chromatin binding#GO:0003682 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000873.3|UniProtKB=G3QF02 G3QF02 SH3YL1 PTHR15629:SF46 SH3YL1 PROTEIN SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1 ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;binding#GO:0005488 regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection assembly#GO:0060491;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;ruffle#GO:0001726;cell projection membrane#GO:0031253 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000013193.3|UniProtKB=G3RBL3 G3RBL3 MRPL38 PTHR11362:SF133 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML38 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000001464.3|UniProtKB=A0A2I2Z316 A0A2I2Z316 IL33 PTHR21114:SF0 DVS27 PROTEIN INTERLEUKIN-33 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;positive regulation of biological process#GO:0048518;regulation of macrophage activation#GO:0043030;defense response to symbiont#GO:0140546;positive regulation of response to external stimulus#GO:0032103;positive regulation of inflammatory response#GO:0050729;positive regulation of leukocyte activation#GO:0002696;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;defense response to bacterium#GO:0042742;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;positive regulation of gene expression#GO:0010628;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;response to external biotic stimulus#GO:0043207;positive regulation of biosynthetic process#GO:0009891;response to bacterium#GO:0009617;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000023516.2|UniProtKB=G3RNZ6 G3RNZ6 FSBP PTHR45629:SF16 SNF2/RAD54 FAMILY MEMBER DNA REPAIR AND RECOMBINATION PROTEIN RAD54B DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;DNA recombination#GO:0006310;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reproductive process#GO:0022414;homologous recombination#GO:0035825;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;organelle fission#GO:0048285 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000027225.2|UniProtKB=G3RRM1 G3RRM1 OR9G1 PTHR24242:SF158 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 9G1-RELATED G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000015373.3|UniProtKB=G3RH79 G3RH79 TMEM70 PTHR13281:SF0 TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001823.3|UniProtKB=G3SAW9 G3SAW9 MSN PTHR23281:SF26 MERLIN/MOESIN/EZRIN/RADIXIN MOESIN protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;cell adhesion molecule binding#GO:0050839 regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of anatomical structure morphogenesis#GO:0022603;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;positive regulation of transport#GO:0051050 actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000009075.3|UniProtKB=G3R120 G3R120 C18H16orf74 PTHR37455:SF1 GENE, 27021-RELATED SIMILAR TO HUMAN CHROMOSOME 16 OPEN READING FRAME 74 temperature homeostasis#GO:0001659;adaptive thermogenesis#GO:1990845;multicellular organismal process#GO:0032501;multicellular organismal-level homeostasis#GO:0048871;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000040151.1|UniProtKB=A0A2I2YAZ3 A0A2I2YAZ3 PTHR10666:SF442 UBIQUITIN UBIQUITIN B LIKE 1 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000006324.3|UniProtKB=G3QTZ7 G3QTZ7 PPP1R15A PTHR16489:SF14 GH11727P PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15A molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 response to endoplasmic reticulum stress#GO:0034976;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to stress#GO:0033554;response to stimulus#GO:0050896 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000015450.3|UniProtKB=G3RHF4 G3RHF4 LMNTD2 PTHR19956:SF5 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 structural molecule activity#GO:0005198 organelle lumen#GO:0043233;organelle envelope#GO:0031967;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882 GORGO|Ensembl=ENSGGOG00000003602.3|UniProtKB=G3QM16 G3QM16 PGS1 PTHR12586:SF1 CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL transferase#PC00220 GORGO|Ensembl=ENSGGOG00000023788.2|UniProtKB=A0A2I2Z3W7 A0A2I2Z3W7 PTHR23087:SF22 NONHISTONE CHROMOSOMAL PROTEIN HMG HIGH MOBILITY GROUP NUCLEOSOME BINDING DOMAIN 1 chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000616.3|UniProtKB=G3QEB5 G3QEB5 VSTM2L PTHR12207:SF31 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000004274.3|UniProtKB=G3QNR7 G3QNR7 KRT12 PTHR23239:SF369 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 12 structural molecule activity#GO:0005198 supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cellular process#GO:0009987;organelle organization#GO:0006996 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000005072.3|UniProtKB=G3QQU6 G3QQU6 ARFIP2 PTHR12141:SF3 ARFAPTIN-RELATED ARFAPTIN-2 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 Huntington disease#P00029>Arfaptin-2#P00793 GORGO|Ensembl=ENSGGOG00000015228.3|UniProtKB=G3RGU7 G3RGU7 PTHR24388:SF48 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR SCRATCH 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016164.3|UniProtKB=G3RJ89 G3RJ89 RPP14 PTHR15441:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P14 RIBONUCLEASE P PROTEIN SUBUNIT P14 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000008896.3|UniProtKB=A0A2I2YES1 A0A2I2YES1 SLC35B2 PTHR10778:SF13 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000002689.3|UniProtKB=G3QJP8 G3QJP8 ULK3 PTHR24348:SF65 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;cellular component organization#GO:0016043;response to starvation#GO:0042594;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;reticulophagy#GO:0061709;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;regulation of catabolic process#GO:0009894;autophagosome assembly#GO:0000045;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;intracellular organelle#GO:0043229;phagophore assembly site#GO:0000407 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006882.3|UniProtKB=G3QVG3 G3QVG3 ELF5 PTHR11849:SF15 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-5 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000015924.3|UniProtKB=G3RIN5 G3RIN5 TEK PTHR24416:SF125 TYROSINE-PROTEIN KINASE RECEPTOR ANGIOPOIETIN-1 RECEPTOR signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of signaling#GO:0023056;angiogenesis#GO:0001525;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;circulatory system development#GO:0072359;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;positive regulation of angiogenesis#GO:0045766;blood vessel morphogenesis#GO:0048514;positive regulation of cell motility#GO:2000147;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of anatomical structure morphogenesis#GO:0022603;endothelial cell proliferation#GO:0001935;epithelial cell proliferation#GO:0050673;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of angiogenesis#GO:0045765;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell population proliferation#GO:0008283;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;positive regulation of signal transduction#GO:0009967;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017;regulation of vasculature development#GO:1901342;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;tube development#GO:0035295;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Tie2#P00247 GORGO|Ensembl=ENSGGOG00000038051.1|UniProtKB=A0A2I2Z297 A0A2I2Z297 ELFN2 PTHR24373:SF263 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 29 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;cellular process#GO:0009987;regulation of biological process#GO:0050789;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000034984.2|UniProtKB=G3SKS0 G3SKS0 ERC2 PTHR18861:SF3 ELKS/RAB6-INTERACTING/CAST PROTEIN ERC PROTEIN 2 structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808 cytoplasm#GO:0005737;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;presynapse#GO:0098793;intracellular anatomical structure#GO:0005622;presynaptic active zone#GO:0048786;cell junction#GO:0030054 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000042704.1|UniProtKB=A0A2I2YWZ0 A0A2I2YWZ0 SFT2D3 PTHR23137:SF36 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2C GORGO|Ensembl=ENSGGOG00000003946.3|UniProtKB=G3QMX2 G3QMX2 ANGPTL3 PTHR19143:SF222 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 3 enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;triglyceride homeostasis#GO:0070328;organophosphate catabolic process#GO:0046434 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000036312.1|UniProtKB=A0A2I2YNZ2 A0A2I2YNZ2 PTHR13058:SF24 THREE PRIME REPAIR EXONUCLEASE 1, 2 THREE PRIME REPAIR EXONUCLEASE 2 3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;DNA catabolic process#GO:0006308;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000003763.3|UniProtKB=G3QMG7 G3QMG7 PRDM16 PTHR24393:SF171 ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM16 transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription coregulator activity#GO:0003712;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009601.3|UniProtKB=G3RZC4 G3RZC4 CPNE3 PTHR10857:SF22 COPINE COPINE-3 receptor tyrosine kinase binding#GO:0030971;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782 response to chemical#GO:0042221;biological regulation#GO:0065007;signal transduction#GO:0007165;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;response to metal ion#GO:0010038;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to calcium ion#GO:0051592;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to chemical stimulus#GO:0070887;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000002264.3|UniProtKB=G3SHB6 G3SHB6 COPZ2 PTHR11043:SF4 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA-2 establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intra-Golgi vesicle-mediated transport#GO:0006891 Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000022210.2|UniProtKB=A0A2I2ZHS9 A0A2I2ZHS9 PTHR28342:SF2 MONOOXYGENASE P33MONOX-RELATED SUBFAMILY NOT NAMED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000016112.3|UniProtKB=G3RJ43 G3RJ43 RHOXF1 PTHR24329:SF549 HOMEOBOX PROTEIN ARISTALESS RHOX HOMEOBOX FAMILY MEMBER 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000000991.3|UniProtKB=G3S6U2 G3S6U2 HM13 PTHR12174:SF23 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane#GO:0016020;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;side of membrane#GO:0098552;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;aspartic protease#PC00053 GORGO|Ensembl=ENSGGOG00000027469.2|UniProtKB=G3S1X8 G3S1X8 PTHR22974:SF25 MIXED LINEAGE PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;chromosome segregation#GO:0007059 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000016595.3|UniProtKB=G3RKD9 G3RKD9 SMC5 PTHR45916:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716 condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000027890.2|UniProtKB=G3S4C2 G3S4C2 LOC101131824 PTHR26453:SF746 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002378.3|UniProtKB=G3S795 G3S795 LAMC1 PTHR10574:SF270 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-1 neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cellular process#GO:0009987;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000004999.3|UniProtKB=G3QQN1 G3QQN1 TFIP11 PTHR23329:SF1 TUFTELIN-INTERACTING PROTEIN 11-RELATED TUFTELIN-INTERACTING PROTEIN 11 protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000023412.2|UniProtKB=G3QM82 G3QM82 CNOT6L PTHR12121:SF35 CARBON CATABOLITE REPRESSOR PROTEIN 4 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311 CCR4-NOT complex#GO:0030014;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000016266.3|UniProtKB=G3RJH3 G3RJH3 PENK PTHR11438:SF3 PROENKEPHALIN PROENKEPHALIN-A signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 system process#GO:0003008;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;sensory perception of pain#GO:0019233;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;organelle lumen#GO:0043233;intracellular vesicle#GO:0097708;cell body#GO:0044297;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;secretory vesicle#GO:0099503;membrane-enclosed lumen#GO:0031974;endomembrane system#GO:0012505;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477 intercellular signal molecule#PC00207;peptide hormone#PC00179;neuropeptide#PC00162 Opioid proenkephalin pathway#P05915>proenkephalin#P05995;Opioid proenkephalin pathway#P05915>Enkephalin#P05991;Enkephalin release#P05913>preproenkephalin mRNA#G06046;Enkephalin release#P05913>preproenkephalin#G06045;Opioid proenkephalin pathway#P05915>peptide F#P05987;Opioid proenkephalin pathway#P05915>leu-Enkephalin#P05989;Enkephalin release#P05913>Enkephalin#P05976;Opioid proenkephalin pathway#P05915>met-Enkephalin#P05992;Opioid proenkephalin pathway#P05915>peptide E#P05988 GORGO|Ensembl=ENSGGOG00000004278.3|UniProtKB=G3SHL3 G3SHL3 KRT20 PTHR23239:SF167 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 20 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000038876.1|UniProtKB=G3RUA1 G3RUA1 PTHR16675:SF257 MHC CLASS I-RELATED IMMUNOGLOBULIN C1-SET DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000027451.2|UniProtKB=G3SI32 G3SI32 ZNF214 PTHR24379:SF132 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 45 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000010156.3|UniProtKB=G3R3S7 G3R3S7 CBY2 PTHR21533:SF13 LEUCINE-RICH PROTEIN PROTEIN CHIBBY HOMOLOG 2 GORGO|Ensembl=ENSGGOG00000001945.3|UniProtKB=G3QHS9 G3QHS9 HOXB13 PTHR45804:SF6 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-B13 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000026396.2|UniProtKB=G3RTK7 G3RTK7 CCDC122 PTHR12138:SF160 PRIMATE-EXPANDED PROTEIN FAMILY COILED-COIL DOMAIN CONTAINING 122 GORGO|Ensembl=ENSGGOG00000013129.3|UniProtKB=A0A2I2ZWV3 A0A2I2ZWV3 RTTN PTHR31691:SF1 ROTATIN ROTATIN cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;organelle assembly#GO:0070925;centriole replication#GO:0007099;cell projection organization#GO:0030030;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;centrosome cycle#GO:0007098;cell cycle process#GO:0022402 centriole#GO:0005814;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000006250.3|UniProtKB=G3SH26 G3SH26 AARSD1 PTHR43462:SF1 ALANYL-TRNA EDITING PROTEIN ALANYL-TRNA EDITING PROTEIN AARSD1 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;deacylase activity#GO:0160215;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;carboxylic ester hydrolase activity#GO:0052689 biological regulation#GO:0065007;regulation of biological quality#GO:0065008 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000025711.2|UniProtKB=G3RMS8 G3RMS8 ZBTB8A PTHR46105:SF12 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006592.3|UniProtKB=G3QUQ2 G3QUQ2 DOT1L PTHR21451:SF0 HISTONE H3 METHYLTRANSFERASE HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular response to stress#GO:0033554;negative regulation of metabolic process#GO:0009892;regulation of cell cycle#GO:0051726;signaling#GO:0023052;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of cell cycle phase transition#GO:1901988;constitutive heterochromatin formation#GO:0140719;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;negative regulation of gene expression, epigenetic#GO:0045814;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of cell cycle process#GO:0010564;heterochromatin organization#GO:0070828;cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;DNA damage checkpoint signaling#GO:0000077;negative regulation of macromolecule metabolic process#GO:0010605;DNA integrity checkpoint signaling#GO:0031570;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000027921.2|UniProtKB=G3RYC7 G3RYC7 DTWD1 PTHR15627:SF15 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 1 catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000013393.3|UniProtKB=G3RC44 G3RC44 SYPL2 PTHR10306:SF8 SYNAPTOPHYSIN SYNAPTOPHYSIN-LIKE PROTEIN 2 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000006423.3|UniProtKB=G3QU82 G3QU82 ATG101 PTHR13292:SF0 AUTOPHAGY-RELATED PROTEIN 101 AUTOPHAGY-RELATED PROTEIN 101 kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 organelle assembly#GO:0070925;metabolic process#GO:0008152;vacuole organization#GO:0007033;autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000042840.1|UniProtKB=A0A2I2YNB2 A0A2I2YNB2 SMIM19 PTHR31888:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 19 SMALL INTEGRAL MEMBRANE PROTEIN 19 GORGO|Ensembl=ENSGGOG00000007338.3|UniProtKB=G3QWM2 G3QWM2 FABP4 PTHR11955:SF83 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, ADIPOCYTE organic acid binding#GO:0043177;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;lipid binding#GO:0008289;fatty acid binding#GO:0005504 lipid transport#GO:0006869;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;lipid localization#GO:0010876 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000004357.3|UniProtKB=G3QNZ3 G3QNZ3 POPDC2 PTHR12101:SF15 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 2 ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 developmental process#GO:0032502;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cell differentiation#GO:0030154 apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;sarcolemma#GO:0042383;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000026704.2|UniProtKB=G3SHH7 G3SHH7 PTHR13681:SF34 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL MOTOR NEURON PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-RNA complex assembly#GO:0022618;anatomical structure development#GO:0048856;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;system development#GO:0048731;RNA splicing, via transesterification reactions#GO:0000375;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;protein-RNA complex organization#GO:0071826;cell projection morphogenesis#GO:0048858;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;RNA splicing#GO:0008380;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cell development#GO:0048468;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;anatomical structure morphogenesis#GO:0009653;RNA metabolic process#GO:0016070;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;nucleic acid biosynthetic process#GO:0141187;generation of neurons#GO:0048699 membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;SMN complex#GO:0032797;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000009030.3|UniProtKB=G3R0Z6 G3R0Z6 NEMF PTHR15239:SF6 NUCLEAR EXPORT MEDIATOR FACTOR NEMF RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF ribosome binding#GO:0043022;tRNA binding#GO:0000049;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;nucleic acid binding#GO:0003676;binding#GO:0005488;ribosomal large subunit binding#GO:0043023 gene expression#GO:0010467;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;rescue of stalled cytosolic ribosome#GO:0072344;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;protein catabolic process#GO:0030163;translation#GO:0006412;modification-dependent macromolecule catabolic process#GO:0043632 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000012975.3|UniProtKB=G3S068 G3S068 SPAG17 PTHR21963:SF1 PF6 SPERM-ASSOCIATED ANTIGEN 17 cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;organelle assembly#GO:0070925;cilium movement#GO:0003341;microtubule-based transport#GO:0099111;microtubule bundle formation#GO:0001578;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017 axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axonemal central apparatus#GO:1990716;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000011947.4|UniProtKB=Q6IV83 Q6IV83 TAFAZZIN PTHR12497:SF8 TAZ PROTEIN TAFAZZIN TAFAZZIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 phospholipid metabolic process#GO:0006644;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;glycerophospholipid metabolic process#GO:0006650;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;cellular component organization or biogenesis#GO:0071840;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000003075.3|UniProtKB=G3QKN9 G3QKN9 ZNF34 PTHR23226:SF271 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 34 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001019.3|UniProtKB=G3QFD6 G3QFD6 PROCR PTHR15349:SF0 ENDOTHELIAL PROTEIN C RECEPTOR ENDOTHELIAL PROTEIN C RECEPTOR biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of coagulation#GO:0050818;negative regulation of coagulation#GO:0050819;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein-binding activity modulator#PC00095 Blood coagulation#P00011>EPCR#P00403 GORGO|Ensembl=ENSGGOG00000006205.3|UniProtKB=G3QTN8 G3QTN8 HSPB3 PTHR47097:SF1 HEAT SHOCK PROTEIN BETA-3 HEAT SHOCK PROTEIN BETA-3 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013467.3|UniProtKB=G3RCA6 G3RCA6 BDKRB2 PTHR24228:SF25 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR B2 BRADYKININ RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;vasodilation#GO:0042311;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of anatomical structure size#GO:0090066;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;blood circulation#GO:0008015;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 GORGO|Ensembl=ENSGGOG00000015015.4|UniProtKB=A0A2I2Y424 A0A2I2Y424 UGT2A2 PTHR48043:SF140 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2A1 glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 GORGO|Ensembl=ENSGGOG00000008719.3|UniProtKB=G3R049 G3R049 PARVB PTHR12114:SF7 PARVIN BETA-PARVIN protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;substrate adhesion-dependent cell spreading#GO:0034446;plasma membrane bounded cell projection assembly#GO:0120031;regulation of developmental process#GO:0050793;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;lamellipodium assembly#GO:0030032;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell-substrate junction#GO:0030055;cell projection#GO:0042995;focal adhesion#GO:0005925;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;lamellipodium#GO:0030027;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell leading edge#GO:0031252;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856 actin and actin related protein#PC00039;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Parvin#P00945 GORGO|Ensembl=ENSGGOG00000026112.2|UniProtKB=A0A2I2Y2J7 A0A2I2Y2J7 TRDMT1 PTHR46098:SF1 TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000042802.1|UniProtKB=A0A2I2YLG0 A0A2I2YLG0 ZNF883 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001177.3|UniProtKB=G3QFT0 G3QFT0 FOXR1 PTHR46789:SF1 FORKHEAD BOX PROTEIN R1 FORKHEAD BOX PROTEIN R1 nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000014510.3|UniProtKB=A0A2I2YC45 A0A2I2YC45 TPM4 PTHR19269:SF75 TROPOMYOSIN TROPOMYOSIN ALPHA-4 CHAIN binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament organization#GO:0007015;system process#GO:0003008;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;muscle contraction#GO:0006936;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;muscle system process#GO:0003012;cellular component organization#GO:0016043;organelle organization#GO:0006996 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;actin filament#GO:0005884;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000001650.3|UniProtKB=A0A2I2ZNE4 A0A2I2ZNE4 MMP14 PTHR10201:SF24 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-14 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 biosynthetic process#GO:0009058;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;metabolic process#GO:0008152;catabolic process#GO:0009056;zymogen activation#GO:0031638;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;external encapsulating structure organization#GO:0045229;system development#GO:0048731;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;skeletal system development#GO:0001501;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153 Gonadotropin-releasing hormone receptor pathway#P06664>MT1-MMP#P06716;Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000009814.3|UniProtKB=A0A2I2YZD2 A0A2I2YZD2 IKZF3 PTHR24404:SF23 ZINC FINGER PROTEIN ZINC FINGER PROTEIN AIOLOS sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014867.3|UniProtKB=G3RFX8 G3RFX8 OGT PTHR44998:SF1 FAMILY NOT NAMED UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 GORGO|Ensembl=ENSGGOG00000012482.3|UniProtKB=G3R9U8 G3R9U8 DDX1 PTHR24031:SF307 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX1 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008310.3|UniProtKB=G3QZ22 G3QZ22 LHX6 PTHR24208:SF121 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX6 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular process#GO:0009987;head development#GO:0060322;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;forebrain development#GO:0030900 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000000055.3|UniProtKB=G3SG51 G3SG51 BSPH1 PTHR22918:SF4 SEMINAL PLASMA PROTEIN BINDER OF SPERM PROTEIN HOMOLOG 1 multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatid development#GO:0007286;spermatid differentiation#GO:0048515;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cell differentiation#GO:0030154;gamete generation#GO:0007276;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;cell maturation#GO:0048469;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;sperm capacitation#GO:0048240;developmental maturation#GO:0021700;male gamete generation#GO:0048232;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000040964.1|UniProtKB=A0A2I2YY92 A0A2I2YY92 PTHR23050:SF531 CALCIUM BINDING PROTEIN CALMODULIN-1 protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;calcium ion binding#GO:0005509;kinase activator activity#GO:0019209;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872 response to metal ion#GO:0010038;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;regulation of monoatomic cation transmembrane transport#GO:1904062;calcium-mediated signaling#GO:0019722;positive regulation of cellular process#GO:0048522;detection of stimulus#GO:0051606;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of monoatomic ion transport#GO:0043269;positive regulation of response to stimulus#GO:0048584;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of transmembrane transport#GO:0034762;calcineurin-mediated signaling#GO:0097720;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of metal ion transport#GO:0010959;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of release of sequestered calcium ion into cytosol#GO:0051279;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;regulation of signaling#GO:0023051;response to calcium ion#GO:0051592;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;detection of chemical stimulus#GO:0009593;signaling#GO:0023052;response to stimulus#GO:0050896 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;myelin sheath#GO:0043209;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305;CCKR signaling map#P06959>CaM#P07193 GORGO|Ensembl=ENSGGOG00000012972.3|UniProtKB=G3RB28 G3RB28 EIF4G2 PTHR23253:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000015467.3|UniProtKB=A0A2I2ZFJ1 A0A2I2ZFJ1 SLC39A12 PTHR12191:SF4 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP12 monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;transition metal ion transmembrane transporter activity#GO:0046915;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385 transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000022090.3|UniProtKB=G3SGL5 G3SGL5 ZDHHC21 PTHR22883:SF11 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC21 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016199.3|UniProtKB=G3RJB6 G3RJB6 MRPL51 PTHR13409:SF0 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L51 LARGE RIBOSOMAL SUBUNIT PROTEIN ML51 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008040.3|UniProtKB=G3QYD3 G3QYD3 R3HDM4 PTHR32019:SF2 R3H DOMAIN-CONTAINING PROTEIN 4 R3H DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000007678.3|UniProtKB=G3RVB1 G3RVB1 RPS27A PTHR10666:SF437 UBIQUITIN POLYUBIQUITIN-B structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;nucleus#GO:0005634;ribosome#GO:0005840;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013799.3|UniProtKB=G3RD67 G3RD67 MTMR4 PTHR10807:SF64 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR4 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;protein phosphatase binding#GO:0019903;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;hydrolase activity#GO:0016787 phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;dephosphorylation#GO:0016311;lipid modification#GO:0030258;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000022552.2|UniProtKB=G3S9F9 G3S9F9 ZGRF1 PTHR28535:SF1 ZINC FINGER GRF-TYPE CONTAINING 1 5'-3' DNA HELICASE ZGRF1 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 membraneless organelle#GO:0043228;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;site of double-strand break#GO:0035861;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000023656.2|UniProtKB=G3S4X4 G3S4X4 OR8K3 PTHR48018:SF28 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011727.3|UniProtKB=G3R7U9 G3R7U9 PTHR10267:SF0 DNA POLYMERASE SUBUNIT GAMMA-1 DNA POLYMERASE SUBUNIT GAMMA-1 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA exonuclease activity#GO:0004529;transferase activity#GO:0016740;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;DNA-directed DNA polymerase activity#GO:0003887;hydrolase activity#GO:0016787 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;mitochondrial DNA metabolic process#GO:0032042;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234 DNA-directed DNA polymerase#PC00018 GORGO|Ensembl=ENSGGOG00000010166.3|UniProtKB=G3R3U2 G3R3U2 CCDC149 PTHR21682:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 GORGO|Ensembl=ENSGGOG00000002865.3|UniProtKB=G3QK49 G3QK49 BORCS6 PTHR13440:SF8 BLOC-1 RELATED COMPLEX SUBUNIT 6 BLOC-1-RELATED COMPLEX SUBUNIT 6 localization#GO:0051179;lysosome localization#GO:0032418;organelle localization#GO:0051640 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000007929.3|UniProtKB=G3QY37 G3QY37 CLSTN2 PTHR14139:SF3 CALSYNTENIN CALSYNTENIN-2 protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;positive regulation of developmental process#GO:0051094;positive regulation of synapse assembly#GO:0051965;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;regulation of synapse assembly#GO:0051963;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 cell junction#GO:0030054;synaptic membrane#GO:0097060;cell surface#GO:0009986;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000007267.4|UniProtKB=A0A2I2ZB65 A0A2I2ZB65 SPRED2 PTHR11202:SF11 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 2 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016234.3|UniProtKB=G3RJE8 G3RJE8 NMUR1 PTHR24243:SF109 G-PROTEIN COUPLED RECEPTOR NEUROMEDIN-U RECEPTOR 1 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016061.3|UniProtKB=G3RIZ7 G3RIZ7 LOC101132777 PTHR15642:SF3 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000008239.3|UniProtKB=G3QYW0 G3QYW0 AURKAIP1 PTHR32035:SF3 AURORA KINASE A-INTERACTING PROTEIN SMALL RIBOSOMAL SUBUNIT PROTEIN BS22, MITOCHONDRIAL GORGO|Ensembl=ENSGGOG00000041030.1|UniProtKB=A0A2I2ZAY5 A0A2I2ZAY5 CEBPG PTHR23334:SF69 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN GAMMA DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015999.3|UniProtKB=G3RIU7 G3RIU7 TRPV5 PTHR10582:SF11 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5 metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;transport#GO:0006810;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;system process#GO:0003008;calcium ion transmembrane import into cytosol#GO:0097553;import into cell#GO:0098657;establishment of localization#GO:0051234;renal absorption#GO:0070293;renal system process#GO:0003014;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002227.3|UniProtKB=G3SDQ5 G3SDQ5 IDH3A PTHR11835:SF34 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cellular process#GO:0009987;alcohol metabolic process#GO:0006066;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176;dehydrogenase#PC00092 Leucine biosynthesis#P02749>3-Isopropylmalate dehydrogenase#P03001 GORGO|Ensembl=ENSGGOG00000008476.3|UniProtKB=G3QZH3 G3QZH3 TMEM11 PTHR15099:SF2 PROTEIN PM1 TRANSMEMBRANE PROTEIN 11, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;cellular component organization#GO:0016043 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743 GORGO|Ensembl=ENSGGOG00000009414.3|UniProtKB=G3R1Y5 G3R1Y5 ABCA1 PTHR19229:SF34 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA1 phosphatidylcholine intramembrane carrier activity#GO:0008525;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 transport#GO:0006810;lipid localization#GO:0010876;establishment of localization#GO:0051234;localization#GO:0051179;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000001923.3|UniProtKB=G3QHR0 G3QHR0 WDR74 PTHR16038:SF4 NOP SEVEN ASSOCIATED PROTEIN 1 WD REPEAT-CONTAINING PROTEIN 74 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000004805.3|UniProtKB=G3QQ49 G3QQ49 DOLK PTHR13205:SF15 TRANSMEMBRANE PROTEIN 15-RELATED DOLICHOL KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000001058.3|UniProtKB=G3QFG9 G3QFG9 PTHR22984:SF26 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE PIM-3 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000038817.1|UniProtKB=A0A2I2YXB7 A0A2I2YXB7 DCAF11 PTHR19847:SF7 DDB1- AND CUL4-ASSOCIATED FACTOR 11 DDB1- AND CUL4-ASSOCIATED FACTOR 11 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000023257.2|UniProtKB=G3RTG2 G3RTG2 PLLP PTHR22776:SF9 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PLASMOLIPIN signaling#GO:0023052;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;myelination#GO:0042552;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989 apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;myelin sheath#GO:0043209;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015810.3|UniProtKB=G3RIC3 G3RIC3 LOC101154047 PTHR47410:SF3 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 9 pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;toll-like receptor signaling pathway#GO:0002224;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;positive regulation of response to stimulus#GO:0048584;canonical NF-kappaB signal transduction#GO:0007249;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of cytokine production#GO:0001817;activation of innate immune response#GO:0002218;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;positive regulation of gene expression#GO:0010628;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;regulation of gene expression#GO:0010468;pattern recognition receptor signaling pathway#GO:0002221;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;response to virus#GO:0009615;intracellular signal transduction#GO:0035556;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 GORGO|Ensembl=ENSGGOG00000007368.3|UniProtKB=G3QWP4 G3QWP4 ABHD4 PTHR42886:SF21 RE40534P-RELATED (LYSO)-N-ACYLPHOSPHATIDYLETHANOLAMINE LIPASE glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;transferase activity#GO:0016740;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid homeostasis#GO:0055088 intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009867.3|UniProtKB=G3R322 G3R322 MEDAG PTHR33769:SF3 TESTIS-EXPRESSED PROTEIN 26 ISOFORM X3 MESENTERIC ESTROGEN-DEPENDENT ADIPOGENESIS PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Gene=TYR|UniProtKB=Q9BDE0 Q9BDE0 TYR PTHR11474:SF124 TYROSINASE FAMILY MEMBER TYROSINASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;phenol-containing compound biosynthetic process#GO:0046189;pigment metabolic process#GO:0042440;phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;melanin biosynthetic process#GO:0042438;secondary metabolic process#GO:0019748;metabolic process#GO:0008152;secondary metabolite biosynthetic process#GO:0044550;pigment biosynthetic process#GO:0046148 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;melanosome#GO:0042470 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000011021.3|UniProtKB=G3R607 G3R607 DUSP13B PTHR45682:SF10 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 13B phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000000707.3|UniProtKB=G3QEJ9 G3QEJ9 PTHR43150:SF1 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-2 alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;ion channel regulator activity#GO:0099106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;protein binding#GO:0005515;channel regulator activity#GO:0016247;binding#GO:0005488;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;transmembrane transporter binding#GO:0044325 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological process#GO:0050789 transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;main axon#GO:0044304;neuron projection#GO:0043005;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;axon#GO:0030424;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 GORGO|Ensembl=ENSGGOG00000009936.3|UniProtKB=G3RXM9 G3RXM9 SEPTIN14 PTHR18884:SF51 SEPTIN SEPTIN-14 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104;cytokinesis#GO:0000910;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000036813.1|UniProtKB=A0A2I2YRF1 A0A2I2YRF1 B4GALT7 PTHR19300:SF30 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 7 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Wnt signaling pathway#P00057>Calcineurin#P01446 GORGO|Ensembl=ENSGGOG00000014688.3|UniProtKB=G3RUH3 G3RUH3 DPM2 PTHR15039:SF11 DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mannosyltransferase complex#GO:0031501;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000041632.1|UniProtKB=G3QV90 G3QV90 ZNF724 PTHR24377:SF938 IP01015P-RELATED ZINC FINGER PROTEIN 429-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015970.3|UniProtKB=G3RIR7 G3RIR7 CPNE6 PTHR10857:SF5 COPINE COPINE-6 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to metal ion#GO:0010038;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to calcium ion#GO:0051592 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000038605.1|UniProtKB=A0A2I2ZBA3 A0A2I2ZBA3 HAUS5 PTHR28588:SF1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000006303.3|UniProtKB=G3SCE1 G3SCE1 MRPS18A PTHR13479:SF66 30S RIBOSOMAL PROTEIN S18 LARGE RIBOSOMAL SUBUNIT PROTEIN ML66 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial large ribosomal subunit#GO:0005762;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000007732.3|UniProtKB=G3QXM0 G3QXM0 NOC2L PTHR12687:SF10 NUCLEOLAR COMPLEX 2 AND RAD4-RELATED NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687 GORGO|Ensembl=ENSGGOG00000043117.1|UniProtKB=A0A2I2YJK0 A0A2I2YJK0 TMEM215 PTHR31922:SF2 TRANSMEMBRANE PROTEIN 215 TRANSMEMBRANE PROTEIN 215 GORGO|Ensembl=ENSGGOG00000005507.3|UniProtKB=G3QRX7 G3QRX7 SCARF1 PTHR24043:SF0 SCAVENGER RECEPTOR CLASS F SCAVENGER RECEPTOR CLASS F MEMBER 1 protein-containing complex binding#GO:0044877;cargo receptor activity#GO:0038024;low-density lipoprotein particle binding#GO:0030169;protein-lipid complex binding#GO:0071814;lipoprotein particle binding#GO:0071813;binding#GO:0005488 positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell maturation#GO:0048469;cellular developmental process#GO:0048869;anatomical structure maturation#GO:0071695;regulation of cellular process#GO:0050794;positive regulation of cell projection organization#GO:0031346;system development#GO:0048731;anatomical structure development#GO:0048856;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell adhesion#GO:0007155;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;positive regulation of neuron projection development#GO:0010976;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;dendrite development#GO:0016358 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000008272.3|UniProtKB=G3QYY5 G3QYY5 MBD3L1 PTHR12396:SF1 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3-LIKE 1 negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of gene expression, epigenetic#GO:0045814;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular component organization or biogenesis#GO:0071840;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008872.3|UniProtKB=A0A2I2Z4W1 A0A2I2Z4W1 IGF2BP1 PTHR10288:SF92 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 mRNA stabilization#GO:0048255;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of RNA stability#GO:0043487 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000017015.3|UniProtKB=A0A2I2YL95 A0A2I2YL95 PHYHD1 PTHR20883:SF15 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000003458.3|UniProtKB=A0A2I2Z047 A0A2I2Z047 BEND2 PTHR47305:SF3 BEN DOMAIN-CONTAINING PROTEIN 2 BEN DOMAIN-CONTAINING PROTEIN 2 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;sexual reproduction#GO:0019953;cellular response to stress#GO:0033554;reproductive process#GO:0022414;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000024072.2|UniProtKB=A0A2I2Y3N8 A0A2I2Y3N8 PTHR11652:SF50 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010235.3|UniProtKB=G3R3Z9 G3R3Z9 NXPH4 PTHR17103:SF10 NEUREXOPHILIN NEUREXOPHILIN-4 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007 GABA-ergic synapse#GO:0098982;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000004851.3|UniProtKB=G3QQ94 G3QQ94 UFSP2 PTHR48153:SF6 UFM1-SPECIFIC PROTEASE 2 UFM1-SPECIFIC PROTEASE 2 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000022367.2|UniProtKB=G3S3R0 G3S3R0 ERCC6L PTHR45629:SF13 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000006857.3|UniProtKB=A0A2I2Z459 A0A2I2Z459 PTHR24068:SF170 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 L5 catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein K11-linked ubiquitination#GO:0070979;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>UbcH7#P01224;Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000002723.3|UniProtKB=A0A2I2YXS1 A0A2I2YXS1 NINJ2 PTHR12316:SF24 NINJURIN-RELATED NINJURIN-2 protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 programmed cell death#GO:0012501;cell adhesion#GO:0007155;cell death#GO:0008219;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000024075.2|UniProtKB=G3RXM4 G3RXM4 PTHR23268:SF42 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 10-1-RELATED signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000007443.3|UniProtKB=G3QWW3 G3QWW3 SACM1L PTHR45662:SF2 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000037197.1|UniProtKB=A0A2I2ZTW0 A0A2I2ZTW0 PTHR24018:SF5 ELASTIN ELASTIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure organization#GO:0045229;system development#GO:0048731;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;tissue remodeling#GO:0048771;animal organ morphogenesis#GO:0009887;circulatory system development#GO:0072359;blood vessel development#GO:0001568;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;vasculature development#GO:0001944;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular process#GO:0009987 supramolecular fiber#GO:0099512;extracellular region#GO:0005576;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000040637.1|UniProtKB=A0A2I2Y348 A0A2I2Y348 PTHR12358:SF89 SPHINGOSINE KINASE ACYLGLYCEROL KINASE, MITOCHONDRIAL phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingoid biosynthetic process#GO:0046520;primary metabolic process#GO:0044238;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000001236.3|UniProtKB=O77486 O77486 FUT2 PTHR11927:SF2 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE GALACTOSIDE ALPHA-(1,2)-FUCOSYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000003361.3|UniProtKB=A0A2I2YSR3 A0A2I2YSR3 AIG1 PTHR10989:SF11 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-INDUCED GENE 1 PROTEIN carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436 GORGO|Ensembl=ENSGGOG00000016375.3|UniProtKB=G3RJT7 G3RJT7 IPO13 PTHR12363:SF33 TRANSPORTIN 3 AND IMPORTIN 13 IMPORTIN-13 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007879.3|UniProtKB=G3RZM9 G3RZM9 PIGQ PTHR21329:SF3 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000036770.1|UniProtKB=A0A2I2ZGY0 A0A2I2ZGY0 LOC101148010 PTHR11165:SF211 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000005286.3|UniProtKB=A0A2I2ZCZ3 A0A2I2ZCZ3 ADO PTHR22966:SF76 2-AMINOETHANETHIOL DIOXYGENASE 2-AMINOETHANETHIOL DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;cellular response to hypoxia#GO:0071456;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to hypoxia#GO:0001666 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000026094.2|UniProtKB=A0A2I2ZA80 A0A2I2ZA80 PTHR24072:SF395 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553 anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;neuron projection guidance#GO:0097485;actin filament organization#GO:0007015;neurogenesis#GO:0022008;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of locomotion#GO:0040012;axon guidance#GO:0007411;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;cell development#GO:0048468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;neuron differentiation#GO:0030182;intracellular signaling cassette#GO:0141124;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell communication#GO:0007154;regulation of cell motility#GO:2000145;supramolecular fiber organization#GO:0097435;system development#GO:0048731;intracellular signal transduction#GO:0035556;cortical cytoskeleton organization#GO:0030865;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of developmental process#GO:0050793;cellular developmental process#GO:0048869;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;Rac protein signal transduction#GO:0016601;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;signaling#GO:0023052;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020;small GTPase#PC00208 CCKR signaling map#P06959>RAC1-GTP#P07214;Huntington disease#P00029>Rac#P00775;EGF receptor signaling pathway#P00018>Rac#P00564;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by semaphorins#P00007>Rac#P00340;VEGF signaling pathway#P00056>Rac#P01421;CCKR signaling map#P06959>RAC1-GDP#P07225;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Integrin signalling pathway#P00034>Rac#P00927;T cell activation#P00053>rac#P01324;Gonadotropin-releasing hormone receptor pathway#P06664>Rac1#P06860;FGF signaling pathway#P00021>Rac#P00645;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rac#P00872;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;Axon guidance mediated by netrin#P00009>Rac#P00366;p38 MAPK pathway#P05918>Rac#P06021;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;B cell activation#P00010>Rac#P00385 GORGO|Ensembl=ENSGGOG00000005639.3|UniProtKB=G3S500 G3S500 WAC PTHR15911:SF6 WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;chromatin binding#GO:0003682;binding#GO:0005488 regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of autophagy#GO:0010506;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012801.3|UniProtKB=G3RAN6 G3RAN6 DDX60 PTHR44533:SF3 DEAD/H RNA HELICASE, PUTATIVE-RELATED ATP-DEPENDENT RNA HELICASE DDX60-RELATED single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676 defense response#GO:0006952;response to external stimulus#GO:0009605;response to virus#GO:0009615;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to stress#GO:0006950;defense response to virus#GO:0051607;response to biotic stimulus#GO:0009607 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000036528.1|UniProtKB=A0A2I2Z042 A0A2I2Z042 PTHR11732:SF450 ALDO/KETO REDUCTASE ALDOSE REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000016125.3|UniProtKB=G3RJ54 G3RJ54 TGM1 PTHR11590:SF49 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE K acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 skin development#GO:0043588;cell differentiation#GO:0030154;epithelium development#GO:0060429;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;animal organ development#GO:0048513;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;epidermis development#GO:0008544;keratinocyte differentiation#GO:0030216 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000026619.2|UniProtKB=G3S0Q7 G3S0Q7 SETD4 PTHR13271:SF164 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE SET DOMAIN-CONTAINING PROTEIN 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938 biological regulation#GO:0065007;chromatin organization#GO:0006325;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;positive regulation of response to external stimulus#GO:0032103;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of inflammatory response#GO:0050729;chromatin remodeling#GO:0006338;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000016009.3|UniProtKB=G3RIV2 G3RIV2 LANCL2 PTHR12736:SF11 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 2 regulation of response to alcohol#GO:1901419;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of abscisic acid-activated signaling pathway#GO:0009787;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of cellular response to alcohol#GO:1905957;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015918.3|UniProtKB=G3RIM1 G3RIM1 C9 PTHR45742:SF3 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C9 response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;immune response#GO:0006955;humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 complement component#PC00078 GORGO|Ensembl=ENSGGOG00000001989.3|UniProtKB=G3S6T6 G3S6T6 MBD6 PTHR16112:SF17 METHYL-CPG BINDING PROTEIN, DROSOPHILA METHYL-CPG-BINDING DOMAIN PROTEIN 6 chromatin binding#GO:0003682;binding#GO:0005488 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010735.3|UniProtKB=G3R599 G3R599 PHC1 PTHR12247:SF20 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 1 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000027576.2|UniProtKB=A0A2I2YGG7 A0A2I2YGG7 PTHR11743:SF55 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic anion channel activity#GO:0008308;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 mitochondrial transport#GO:0006839;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transmembrane transport#GO:0055085;intracellular transport#GO:0046907;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;cell periphery#GO:0071944;mitochondrial envelope#GO:0005740;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000015710.3|UniProtKB=G3RI40 G3RI40 ACTL6A PTHR11937:SF487 ACTIN ACTIN-LIKE PROTEIN 6A chromatin binding#GO:0003682;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000014568.3|UniProtKB=G3SHB7 G3SHB7 PINK1 PTHR22972:SF7 SERINE/THREONINE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PINK1, MITOCHONDRIAL protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of programmed cell death#GO:0043067;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;positive regulation of cellular component organization#GO:0051130;process utilizing autophagic mechanism#GO:0061919;positive regulation of organelle organization#GO:0010638;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;positive regulation of developmental process#GO:0051094;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;regulation of anatomical structure morphogenesis#GO:0022603 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012113.3|UniProtKB=G3R8U7 G3R8U7 C10H12orf43 PTHR14482:SF0 CHROMOSOME 12 ORF 43 HOMOLOG PROTEIN CUSTOS negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;anatomical structure development#GO:0048856 GORGO|Ensembl=ENSGGOG00000004801.3|UniProtKB=G3QQ47 G3QQ47 ZGPAT PTHR46297:SF1 ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009631.3|UniProtKB=G3R2F3 G3R2F3 TRIM55 PTHR24103:SF640 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 55 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023859.2|UniProtKB=G3SI47 G3SI47 GOLGA4 PTHR19327:SF0 GOLGIN GOLGIN SUBFAMILY A MEMBER 4 small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000011313.3|UniProtKB=A0A2I2ZFC8 A0A2I2ZFC8 RBBP4 PTHR22850:SF90 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP4 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;PcG protein complex#GO:0031519;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 GORGO|Ensembl=ENSGGOG00000009424.3|UniProtKB=G3R1X7 G3R1X7 MIPEP PTHR11804:SF79 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED MITOCHONDRIAL INTERMEDIATE PEPTIDASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000002602.3|UniProtKB=G3QJH0 G3QJH0 STX4 PTHR19957:SF97 SYNTAXIN SYNTAXIN-4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 intracellular protein localization#GO:0008104;exocytosis#GO:0006887;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;organelle organization#GO:0006996;secretion by cell#GO:0032940;protein transport#GO:0015031;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;export from cell#GO:0140352;vesicle fusion#GO:0006906;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 GORGO|Ensembl=ENSGGOG00000016476.3|UniProtKB=G3S195 G3S195 ZCCHC4 PTHR13493:SF3 ZINC FINGER CCHC DOMAIN-CONTAINING RRNA N(6)-ADENOSINE-METHYLTRANSFERASE ZCCHC4 catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102 rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000002276.3|UniProtKB=G3QIM8 G3QIM8 BTBD9 PTHR46306:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 9 BTB_POZ DOMAIN-CONTAINING PROTEIN 9 rhythmic process#GO:0048511;regulation of signaling#GO:0023051;circadian rhythm#GO:0007623;regulation of biological process#GO:0050789;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013368.3|UniProtKB=G3RC21 G3RC21 GABRR2 PTHR18945:SF197 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-2 chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;channel activity#GO:0015267 chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052 signaling receptor complex#GO:0043235;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;GABA-ergic synapse#GO:0098982;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000007646.3|UniProtKB=G3QXD6 G3QXD6 SLC10A4 PTHR10361:SF41 SODIUM-BILE ACID COTRANSPORTER SODIUM_BILE ACID COTRANSPORTER 4-RELATED active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;bile acid transmembrane transporter activity#GO:0015125;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;bile acid and bile salt transport#GO:0015721;establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000003978.3|UniProtKB=A0A2I2Z4B3 A0A2I2Z4B3 TH PTHR11473:SF18 AROMATIC AMINO ACID HYDROXYLASE TYROSINE 3-MONOOXYGENASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;system process#GO:0003008;synaptic transmission, dopaminergic#GO:0001963;cellular process#GO:0009987;phenol-containing compound biosynthetic process#GO:0046189;synaptic signaling#GO:0099536;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;cell-cell signaling#GO:0007267;biosynthetic process#GO:0009058;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;trans-synaptic signaling#GO:0099537;cognition#GO:0050890;multicellular organismal reproductive process#GO:0048609;cell communication#GO:0007154;catecholamine metabolic process#GO:0006584;regulation of biological process#GO:0050789;phenol-containing compound metabolic process#GO:0018958;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;reproductive process#GO:0022414;anterograde trans-synaptic signaling#GO:0098916 intracellular anatomical structure#GO:0005622;perikaryon#GO:0043204;axon#GO:0030424;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Nicotine pharmacodynamics pathway#P06587>TH#P06614;Parkinson disease#P00049>TH#P01241;Adrenaline and noradrenaline biosynthesis#P00001>TH#P00062;Dopamine receptor mediated signaling pathway#P05912>TH#P05970 GORGO|Ensembl=ENSGGOG00000005357.3|UniProtKB=G3QRJ1 G3QRJ1 PILRA PTHR15549:SF26 PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR ALPHA-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000000433.3|UniProtKB=G3SJ23 G3SJ23 ZBTB47 PTHR24394:SF24 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 47 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000026244.2|UniProtKB=G3S8I2 G3S8I2 PRR14L PTHR14522:SF0 EMO2-RELATED PROTEIN PRR14L GORGO|Ensembl=ENSGGOG00000010322.3|UniProtKB=G3R482 G3R482 IDUA PTHR12631:SF8 ALPHA-L-IDURONIDASE ALPHA-L-IDURONIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 hydrolase#PC00121;glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000006708.3|UniProtKB=G3QV06 G3QV06 ARMC6 PTHR22895:SF9 ARMADILLO REPEAT-CONTAINING PROTEIN 6 ARMADILLO REPEAT-CONTAINING PROTEIN 6 anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cell development#GO:0048468;hemopoiesis#GO:0030097;cellular process#GO:0009987;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000012858.3|UniProtKB=A0A2I2ZVF1 A0A2I2ZVF1 CAPN9 PTHR10183:SF385 CALPAIN CALPAIN-9 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000002307.3|UniProtKB=G3QIQ5 G3QIQ5 KLHL4 PTHR24412:SF74 KELCH PROTEIN KELCH-LIKE PROTEIN 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011480.3|UniProtKB=G3R767 G3R767 LATS2 PTHR24356:SF149 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE LATS2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;hippo signaling#GO:0035329;cell cycle G1/S phase transition#GO:0044843;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;G1/S transition of mitotic cell cycle#GO:0000082;regulation of developmental process#GO:0050793;signaling#GO:0023052;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;positive regulation of programmed cell death#GO:0043068;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of programmed cell death#GO:0043067;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic cell cycle phase transition#GO:0044772 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000039392.1|UniProtKB=A0A2I2Y9Y4 A0A2I2Y9Y4 DIRAS2 PTHR24070:SF178 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS2 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000013266.3|UniProtKB=G3RBT5 G3RBT5 PPFIA1 PTHR12587:SF15 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;cellular component organization#GO:0016043;synapse organization#GO:0050808;cellular process#GO:0009987 presynapse#GO:0098793;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;presynaptic active zone#GO:0048786 scaffold/adaptor protein#PC00226 GORGO|Gene=LEP|UniProtKB=Q95189 Q95189 LEP PTHR11724:SF1 LEPTIN LEPTIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to hormone#GO:0009725;regulation of biological quality#GO:0065008;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;energy derivation by oxidation of organic compounds#GO:0015980;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;lipid metabolic process#GO:0006629;regulation of response to stimulus#GO:0048583;generation of precursor metabolites and energy#GO:0006091;response to peptide hormone#GO:0043434;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;energy reserve metabolic process#GO:0006112;cytokine-mediated signaling pathway#GO:0019221;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000009593.3|UniProtKB=A0A2I2Y4G7 A0A2I2Y4G7 ZFYVE21 PTHR39490:SF8 ARRESTIN DOMAIN-CONTAINING PROTEIN D ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21 GORGO|Ensembl=ENSGGOG00000007450.3|UniProtKB=G3QWW5 G3QWW5 RPS13 PTHR11885:SF20 RIBOSOMAL PROTEIN S15P/S13E SMALL RIBOSOMAL SUBUNIT PROTEIN US15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774 cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000014722.3|UniProtKB=G3RFJ4 G3RFJ4 MRPL54 PTHR28595:SF1 39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML54 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000007449.3|UniProtKB=G3QWW6 G3QWW6 ELOVL2 PTHR11157:SF16 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000016349.3|UniProtKB=G3SAR0 G3SAR0 SLC6A16 PTHR11616:SF327 SODIUM/CHLORIDE DEPENDENT TRANSPORTER ORPHAN SODIUM- AND CHLORIDE-DEPENDENT NEUROTRANSMITTER TRANSPORTER NTT5 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 GORGO|Ensembl=ENSGGOG00000007569.3|UniProtKB=G3QX76 G3QX76 ENOX2 PTHR16001:SF7 ANGEL WING family ECTO-NOX DISULFIDE-THIOL EXCHANGER 2 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009662.4|UniProtKB=G3R2I2 G3R2I2 LOC101124249 PTHR24304:SF0 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 7B1 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;lipid homeostasis#GO:0055088;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;homeostatic process#GO:0042592;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;small molecule biosynthetic process#GO:0044283;cholesterol homeostasis#GO:0042632;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000003230.3|UniProtKB=G3QL31 G3QL31 CD4 PTHR11422:SF0 T-CELL SURFACE GLYCOPROTEIN CD4 T-CELL SURFACE GLYCOPROTEIN CD4 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000043813.1|UniProtKB=A0A2I2YN48 A0A2I2YN48 LOC101131861 PTHR15197:SF0 COILIN P80 COILIN binding#GO:0005488;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000028077.2|UniProtKB=G3RZB2 G3RZB2 SNRPA1 PTHR10552:SF11 U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A' snRNA binding#GO:0017069;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;U2 snRNP#GO:0005686;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000041875.1|UniProtKB=A0A2I2ZNH4 A0A2I2ZNH4 PWP2 PTHR19858:SF0 WD40 REPEAT PROTEIN PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000025562.2|UniProtKB=G3S653 G3S653 CBLC PTHR23007:SF12 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL-C catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;receptor tyrosine kinase binding#GO:0030971;acyltransferase activity#GO:0016746;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857;cell periphery#GO:0071944 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 GORGO|Ensembl=ENSGGOG00000007593.3|UniProtKB=G3S620 G3S620 WDR75 PTHR44215:SF1 WD REPEAT-CONTAINING PROTEIN 75 WD REPEAT-CONTAINING PROTEIN 75 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase I#GO:0045943;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000015161.3|UniProtKB=G3RGP1 G3RGP1 CCND3 PTHR10177:SF65 CYCLINS G1_S-SPECIFIC CYCLIN-D3 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell cycle G1/S phase transition#GO:0044843;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;mitotic cell cycle phase transition#GO:0044772;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228 kinase activator#PC00138 Cell cycle#P00013>Cyclin D#P00484 GORGO|Ensembl=ENSGGOG00000002971.3|UniProtKB=G3RTG5 G3RTG5 ATG4A PTHR22624:SF35 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4A cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;protein metabolic process#GO:0019538;proteolysis#GO:0006508;organelle assembly#GO:0070925;biosynthetic process#GO:0009058;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;autophagy#GO:0006914;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;mitophagy#GO:0000423;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000039079.1|UniProtKB=A0A2I2YEV4 A0A2I2YEV4 PTHR13286:SF7 SAP30 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 protein-containing complex#GO:0032991;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004053.3|UniProtKB=A0A2I2ZRW7 A0A2I2ZRW7 ZFX PTHR24409:SF313 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN X-LINKED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009885.3|UniProtKB=G3R340 G3R340 SHPK PTHR10196:SF67 SUGAR KINASE SEDOHEPTULOKINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 generation of precursor metabolites and energy#GO:0006091;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;response to other organism#GO:0051707;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;pentose-phosphate shunt#GO:0006098;response to bacterium#GO:0009617;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;glucose 6-phosphate metabolic process#GO:0051156;metabolic process#GO:0008152;response to lipopolysaccharide#GO:0032496;nucleobase-containing small molecule metabolic process#GO:0055086;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;regulation of macrophage activation#GO:0043030;cellular response to oxygen-containing compound#GO:1901701;nicotinamide nucleotide metabolic process#GO:0046496;cellular response to lipopolysaccharide#GO:0071222;NADP+ metabolic process#GO:0006739;response to biotic stimulus#GO:0009607;regulation of multicellular organismal process#GO:0051239;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;glyceraldehyde-3-phosphate metabolic process#GO:0019682;cellular response to chemical stimulus#GO:0070887;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;regulation of cell activation#GO:0050865;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;regulation of leukocyte activation#GO:0002694;biological process involved in interspecies interaction between organisms#GO:0044419;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 carbohydrate kinase#PC00065;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000038147.1|UniProtKB=A0A2I2ZCB6 A0A2I2ZCB6 LOC129529113 PTHR35157:SF1 PROTEIN FAM209A PROTEIN FAM209A GORGO|Ensembl=ENSGGOG00000040520.1|UniProtKB=A0A2I2YGB3 A0A2I2YGB3 PTHR13980:SF15 CDC68 RELATED FACT COMPLEX SUBUNIT SPT16 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;protein carrier activity#GO:0140597;chromatin binding#GO:0003682;molecular carrier activity#GO:0140104;binding#GO:0005488 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000009691.3|UniProtKB=G3S0B5 G3S0B5 VSTM2B PTHR12207:SF27 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2B membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000014802.3|UniProtKB=G3RFS0 G3RFS0 SMU1 PTHR22848:SF2 WD40 REPEAT PROTEIN WD40 REPEAT-CONTAINING PROTEIN SMU1 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000008574.3|UniProtKB=G3QZR9 G3QZR9 ASB15 PTHR24198:SF187 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND SOCS BOX CONTAINING 15 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000040617.1|UniProtKB=A0A2I2YEX7 A0A2I2YEX7 PTHR46131:SF7 SD08549P SOLUTE CARRIER FAMILY 25 MEMBER 51 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;purine nucleotide transmembrane transporter activity#GO:0015216;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000000946.3|UniProtKB=G3S2F4 G3S2F4 KMT2A PTHR45838:SF2 HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE 2A protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680 organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000016549.3|UniProtKB=A0A2I2ZNP9 A0A2I2ZNP9 ATF7IP2 PTHR23210:SF23 ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000000943.3|UniProtKB=G3QF64 G3QF64 FPGS PTHR11136:SF5 FOLYLPOLYGLUTAMATE SYNTHASE-RELATED FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ligase#PC00142 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate synthase#P02958;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 GORGO|Ensembl=ENSGGOG00000007599.4|UniProtKB=G3QX99 G3QX99 SPIDR PTHR34347:SF1 DNA REPAIR-SCAFFOLDING PROTEIN SPIDR DNA REPAIR-SCAFFOLDING PROTEIN biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;regulation of localization#GO:0032879;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000022146.2|UniProtKB=G3SIP7 G3SIP7 PCTP PTHR19308:SF59 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN PHOSPHATIDYLCHOLINE TRANSFER PROTEIN phosphatidylcholine binding#GO:0031210;phospholipid binding#GO:0005543;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303;lipid binding#GO:0008289;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylcholine intramembrane carrier activity#GO:0008525;molecular carrier activity#GO:0140104;ion binding#GO:0043167;lipid carrier activity#GO:0005319 GORGO|Ensembl=ENSGGOG00000010977.3|UniProtKB=G3SDD7 G3SDD7 FAM184A PTHR18870:SF7 PROTEIN TAG-278-RELATED PROTEIN FAM184A GORGO|Ensembl=ENSGGOG00000013319.3|UniProtKB=A0A2I2YYT5 A0A2I2YYT5 ANKRD16 PTHR24173:SF95 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001656.3|UniProtKB=G3QH37 G3QH37 HMCN1 PTHR44888:SF3 HEPACAM FAMILY MEMBER 2-RELATED HEMICENTIN-2 ISOFORM X1 GORGO|Ensembl=ENSGGOG00000001940.3|UniProtKB=G3QHS7 G3QHS7 PTHR15749:SF4 FANCONI-ASSOCIATED NUCLEASE 1 FANCONI-ASSOCIATED NUCLEASE 1 GORGO|Ensembl=ENSGGOG00000004523.3|UniProtKB=G3QPE2 G3QPE2 STYXL2 PTHR45682:SF4 AGAP008228-PA SERINE_THREONINE_TYROSINE-INTERACTING-LIKE PROTEIN 2 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000007387.3|UniProtKB=G3RNJ5 G3RNJ5 MARK3 PTHR24346:SF1 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP_MICROTUBULE AFFINITY-REGULATING KINASE 3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000028394.3|UniProtKB=G3S5S3 G3S5S3 TTLL7 PTHR12241:SF147 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL7 binding#GO:0005488;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000014233.3|UniProtKB=G3REA1 G3REA1 BRICD5 PTHR16483:SF0 GASTROKINE 1 BRICHOS DOMAIN-CONTAINING PROTEIN 5 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013499.3|UniProtKB=A0A2I2ZWN3 A0A2I2ZWN3 EYA4 PTHR10190:SF17 EYES ABSENT PROTEIN PHOSPHATASE EYA4 hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of DNA metabolic process#GO:0051052;regulation of cellular response to stress#GO:0080135;ear development#GO:0043583;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;inner ear development#GO:0048839;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;sensory organ development#GO:0007423;regulation of response to stress#GO:0080134;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of DNA metabolic process#GO:0051054;anatomical structure development#GO:0048856 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000000487.3|UniProtKB=G3QDZ4 G3QDZ4 TOM1L2 PTHR13856:SF31 VHS DOMAIN CONTAINING PROTEIN FAMILY TOM1-LIKE PROTEIN 2 binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000012495.3|UniProtKB=G3R9U0 G3R9U0 LAMTOR1 PTHR13401:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000012243.3|UniProtKB=G3R969 G3R969 SH2D3A PTHR14247:SF11 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 3A GORGO|Ensembl=ENSGGOG00000007582.3|UniProtKB=G3QX85 G3QX85 MMRN1 PTHR15427:SF3 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER MULTIMERIN-1 protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell adhesion mediated by integrin#GO:0033627;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of platelet activation#GO:0010543;regulation of platelet aggregation#GO:0090330;cell adhesion#GO:0007155;regulation of biological process#GO:0050789;positive regulation of cell adhesion#GO:0045785;regulation of cell activation#GO:0050865;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007897.3|UniProtKB=G3QY11 G3QY11 COMP PTHR10199:SF88 THROMBOSPONDIN CARTILAGE OLIGOMERIC MATRIX PROTEIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 tissue development#GO:0009888;anatomical structure development#GO:0048856;connective tissue development#GO:0061448;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000003109.3|UniProtKB=G3QKS2 G3QKS2 TMIE PTHR28635:SF1 TRANSMEMBRANE INNER EAR EXPRESSED PROTEIN TRANSMEMBRANE INNER EAR EXPRESSED PROTEIN system process#GO:0003008;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;developmental process#GO:0032502;sensory organ development#GO:0007423;embryo development#GO:0009790;multicellular organismal process#GO:0032501;inner ear development#GO:0048839;inner ear morphogenesis#GO:0042472;ear development#GO:0043583;anatomical structure development#GO:0048856;nervous system process#GO:0050877;embryonic organ development#GO:0048568;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;sensory perception of sound#GO:0007605;anatomical structure morphogenesis#GO:0009653 GORGO|Ensembl=ENSGGOG00000010707.3|UniProtKB=G3R573 G3R573 PSME3 PTHR10660:SF4 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 3 peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134;enzyme activator activity#GO:0008047;endopeptidase regulator activity#GO:0061135;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of mitotic cell cycle#GO:0007346;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of proteasomal protein catabolic process#GO:0061136;regulation of catabolic process#GO:0009894;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of protein catabolic process#GO:0042176;regulation of mitotic cell cycle phase transition#GO:1901990 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 Cell cycle#P00013>Proteasome#P00480 GORGO|Ensembl=ENSGGOG00000022251.2|UniProtKB=G3S709 G3S709 PTHR11851:SF200 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585 cytoplasm#GO:0005737;peptidase complex#GO:1905368;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;endopeptidase complex#GO:1905369;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000012096.3|UniProtKB=G3R8T7 G3R8T7 STARD8 PTHR12659:SF3 RHO-TYPE GTPASE ACTIVATING PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 8 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;actin filament-based process#GO:0030029;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000001958.3|UniProtKB=G3QHU3 G3QHU3 TCP11L2 PTHR12832:SF17 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11-LIKE PROTEIN 2 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000023889.2|UniProtKB=G3SJP3 G3SJP3 LOC101127689 PTHR23087:SF13 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-17 chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010956.3|UniProtKB=G3R5U2 G3R5U2 TMUB2 PTHR14557:SF4 PROTEIN C7ORF21 TRANSMEMBRANE AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN 2 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 GORGO|Ensembl=ENSGGOG00000008419.3|UniProtKB=G3RZD2 G3RZD2 PLCB4 PTHR10336:SF36 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4 hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 phosphatidylinositol metabolic process#GO:0046488;transport#GO:0006810;lipid metabolic process#GO:0006629;establishment of localization#GO:0051234;organophosphate metabolic process#GO:0019637;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;signal transduction#GO:0007165;glycerophospholipid metabolic process#GO:0006650;monoatomic cation transmembrane transport#GO:0098655;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;phosphorus metabolic process#GO:0006793;calcium ion transmembrane transport#GO:0070588;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052 lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;hydrolase#PC00121 Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Metabotropic glutamate receptor group I pathway#P00041>PLC#P01053;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Endothelin signaling pathway#P00019>PLCbeta#P00591;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PLC#P01068;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Wnt signaling pathway#P00057>Phospholipase C#P01443;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874 GORGO|Ensembl=ENSGGOG00000026298.2|UniProtKB=Q0ZQL0 Q0ZQL0 PPIA PTHR11071:SF490 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Gene=CXCR1|UniProtKB=P55919 P55919 CXCR1 PTHR10489:SF916 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 1 cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;granulocyte migration#GO:0097530;taxis#GO:0042330;neutrophil migration#GO:1990266;response to chemical#GO:0042221;neutrophil chemotaxis#GO:0030593;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;regulation of biological quality#GO:0065008;immune response#GO:0006955;biological regulation#GO:0065007;cell migration#GO:0016477;leukocyte migration#GO:0050900;leukocyte chemotaxis#GO:0030595;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cell communication#GO:0007154 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854;Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000008341.3|UniProtKB=G3S813 G3S813 IRF7 PTHR11949:SF2 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 7 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Toll receptor signaling pathway#P00054>IRF3#P01374 GORGO|Ensembl=ENSGGOG00000014132.3|UniProtKB=G3RE20 G3RE20 MED4 PTHR13208:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000005798.3|UniProtKB=G3QSN6 G3QSN6 ARRDC2 PTHR11188:SF48 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000008698.3|UniProtKB=A0A2I2ZPW0 A0A2I2ZPW0 ARHGAP20 PTHR23179:SF28 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED RHO GTPASE-ACTIVATING PROTEIN 20 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000044141.1|UniProtKB=A0A2I2ZMH5 A0A2I2ZMH5 PTHR24088:SF1 28S RIBOSOMAL PROTEIN S17, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US17M ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013439.3|UniProtKB=G3RC90 G3RC90 CEP104 PTHR13371:SF0 GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN CENTROSOMAL PROTEIN OF 104 KDA cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015022.3|UniProtKB=A0A2I2YIB0 A0A2I2YIB0 PXK PTHR22999:SF40 PX SERINE/THREONINE KINASE PXK PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000036930.1|UniProtKB=A0A2I2Z7V4 A0A2I2Z7V4 PTHR12763:SF43 FAMILY NOT NAMED SUBFAMILY NOT NAMED ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743 membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;organelle lumen#GO:0043233;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011566.3|UniProtKB=G3R7E3 G3R7E3 LOC101143299 PTHR12538:SF7 40S RIBOSOMAL PROTEIN S26 SMALL RIBOSOMAL SUBUNIT PROTEIN ES26-RELATED structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003147.3|UniProtKB=G3S171 G3S171 MDM1 PTHR32078:SF1 NUCLEAR PROTEIN MDM1 STABILIZER OF AXONEMAL MICROTUBULES 6 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;retina development in camera-type eye#GO:0060041;camera-type eye development#GO:0043010;regulation of microtubule-based process#GO:0032886;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;visual system development#GO:0150063;regulation of cell cycle#GO:0051726 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriolar satellite#GO:0034451;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000011214.3|UniProtKB=G3R6H8 G3R6H8 DOHH PTHR12697:SF42 PBS LYASE HEAT-LIKE PROTEIN DEOXYHYPUSINE HYDROXYLASE oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 lyase#PC00144 GORGO|Ensembl=ENSGGOG00000008704.3|UniProtKB=G3R034 G3R034 SYN1 PTHR10841:SF24 SYNAPSIN SYNAPSIN-1 cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;cellular component organization#GO:0016043;cell junction organization#GO:0034330;organelle localization#GO:0051640;synapse organization#GO:0050808;localization#GO:0051179;cellular localization#GO:0051641 cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>Synapsin#P05775 GORGO|Ensembl=ENSGGOG00000025154.2|UniProtKB=G3RYJ0 G3RYJ0 ACBD5 PTHR23310:SF6 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5 lipid binding#GO:0008289;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000006229.3|UniProtKB=G3QTR3 G3QTR3 NME3 PTHR11349:SF54 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE C nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776 metabolic process#GO:0008152;nucleoside triphosphate biosynthetic process#GO:0009142;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleoside triphosphate metabolic process#GO:0009141 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 kinase#PC00137;transferase#PC00220 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 GORGO|Ensembl=ENSGGOG00000023837.2|UniProtKB=G3RU27 G3RU27 LOC101150037 PTHR48018:SF75 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015310.3|UniProtKB=G3RH23 G3RH23 SH3GLB2 PTHR14167:SF68 SH3 DOMAIN-CONTAINING ENDOPHILIN-B2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000036989.1|UniProtKB=G3SDT0 G3SDT0 LOC101125134 PTHR23428:SF322 HISTONE H2B HISTONE H2B TYPE 2-E innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;defense response#GO:0006952;response to external stimulus#GO:0009605;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000006801.3|UniProtKB=G3RZJ9 G3RZJ9 SHISA4 PTHR31395:SF5 SHISA PROTEIN SHISA-4 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001280.3|UniProtKB=G3QG16 G3QG16 ACSS1 PTHR24095:SF110 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE 2-LIKE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 GORGO|Ensembl=ENSGGOG00000004556.3|UniProtKB=G3QPH3 G3QPH3 RAP1GDS1 PTHR10957:SF2 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000006260.3|UniProtKB=G3QTT9 G3QTT9 PTHR11929:SF227 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE FUT6 alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000022603.2|UniProtKB=A0A2I2Z4Q8 A0A2I2Z4Q8 ALG11 PTHR45919:SF1 GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000037903.1|UniProtKB=A0A2I2ZE54 A0A2I2ZE54 PTHR13479:SF56 30S RIBOSOMAL PROTEIN S18 MITOCHONDRIAL RIBOSOMAL PROTEIN S18C structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012644.3|UniProtKB=G3RA77 G3RA77 PTHR43696:SF9 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 GORGO|Ensembl=ENSGGOG00000026737.2|UniProtKB=A0A2I2ZBP8 A0A2I2ZBP8 CSF2RB PTHR23037:SF22 CYTOKINE RECEPTOR CYTOKINE RECEPTOR COMMON SUBUNIT BETA cytokine receptor activity#GO:0004896;coreceptor activity#GO:0015026;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cytokine-mediated signaling pathway#GO:0019221;immune system process#GO:0002376;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;response to peptide#GO:1901652;immunoglobulin mediated immune response#GO:0016064;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of leukocyte proliferation#GO:0070665;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;regulation of leukocyte proliferation#GO:0070663;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;immune response#GO:0006955;positive regulation of biological process#GO:0048518;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway via STAT#GO:0097696;adaptive immune response#GO:0002250;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 GORGO|Ensembl=ENSGGOG00000021948.2|UniProtKB=G3SFE9 G3SFE9 SC5D PTHR11863:SF247 STEROL DESATURASE LATHOSTEROL OXIDASE catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000003582.3|UniProtKB=G3QLZ6 G3QLZ6 CASP2 PTHR10454:SF250 CASPASE CASPASE-2 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;signaling#GO:0023052;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;positive regulation of apoptotic process#GO:0043065;positive regulation of neuron apoptotic process#GO:0043525;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;DNA damage response#GO:0006974;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of neuron apoptotic process#GO:0043523;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000038945.1|UniProtKB=A0A2I2YLR9 A0A2I2YLR9 LOC101127525 PTHR24353:SF133 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell adhesion#GO:0007155;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186 protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Enkephalin release#P05913>PKA#P05972;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946 GORGO|Ensembl=ENSGGOG00000024769.2|UniProtKB=G3S0V7 G3S0V7 SSR2 PTHR12861:SF3 TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011009.3|UniProtKB=G3R602 G3R602 TRHDE PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000000992.3|UniProtKB=G3QFB1 G3QFB1 LOC101128369 PTHR13831:SF0 MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS PROTEIN HIRA protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000001326.3|UniProtKB=A0A2I2ZC48 A0A2I2ZC48 PTHR24228:SF11 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR TYPE-1 ANGIOTENSIN II RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 developmental process#GO:0032502;system process#GO:0003008;defense response#GO:0006952;regulation of blood pressure#GO:0008217;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;circulatory system process#GO:0003013;inflammatory response#GO:0006954;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;response to nitrogen compound#GO:1901698;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;multicellular organism development#GO:0007275;animal organ development#GO:0048513;renal system development#GO:0072001;kidney development#GO:0001822;response to stress#GO:0006950;response to hormone#GO:0009725;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;response to oxygen-containing compound#GO:1901700;regulation of biological quality#GO:0065008;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>AT1-R#P05924 GORGO|Ensembl=ENSGGOG00000042844.1|UniProtKB=A0A2I2ZN68 A0A2I2ZN68 IRF2BP2 PTHR10816:SF18 MYELIN TRANSCRIPTION FACTOR 1-RELATED INTERFERON REGULATORY FACTOR 2-BINDING PROTEIN 2 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000002915.3|UniProtKB=G3QK96 G3QK96 RPP25L PTHR13516:SF8 RIBONUCLEASE P SUBUNIT P25 RIBONUCLEASE P PROTEIN SUBUNIT P25-LIKE PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular protein-containing complex#GO:0140535;ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004894.3|UniProtKB=G3QQD0 G3QQD0 CCN6 PTHR11348:SF3 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CELLULAR COMMUNICATION NETWORK FACTOR 6 glycosaminoglycan binding#GO:0005539;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178 regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 growth factor#PC00112;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000028145.2|UniProtKB=G3RNL1 G3RNL1 LOC101124446 PTHR24408:SF37 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001779.3|UniProtKB=G3QHC8 G3QHC8 SATB1 PTHR15116:SF14 DNA-BINDING PROTEIN SATB FAMILY MEMBER DNA-BINDING PROTEIN SATB1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000026470.2|UniProtKB=A0A2I2Z9R8 A0A2I2Z9R8 PTHR21646:SF53 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosome organization#GO:0007032;organelle organization#GO:0006996;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein stability#GO:0031647;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of Wnt signaling pathway#GO:0030177;endomembrane system organization#GO:0010256;intracellular signaling cassette#GO:0141124;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 cytoplasm#GO:0005737;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic specialization#GO:0099572;midbody#GO:0030496;postsynapse#GO:0098794;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;postsynaptic density#GO:0014069 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000026044.2|UniProtKB=G3RSZ8 G3RSZ8 PTHR12159:SF9 G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 GORGO|Ensembl=ENSGGOG00000023581.2|UniProtKB=G3S8E4 G3S8E4 PTHR11544:SF147 COLD SHOCK DOMAIN CONTAINING PROTEINS CSD DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000011563.3|UniProtKB=G3R7D8 G3R7D8 EDDM3B PTHR16788:SF0 EPIDIDYMAL SECRETORY PROTEIN E3 ALPHA EPIDIDYMAL SECRETORY PROTEIN E3-BETA GORGO|Ensembl=ENSGGOG00000013607.3|UniProtKB=G3RCS6 G3RCS6 TRIO PTHR22826:SF104 RHO GUANINE EXCHANGE FACTOR-RELATED TRIPLE FUNCTIONAL DOMAIN PROTEIN molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175 extrinsic component of membrane#GO:0019898;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000000244.3|UniProtKB=G3QDC8 G3QDC8 SMYD4 PTHR46165:SF2 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 PROTEIN-LYSINE N-METHYLTRANSFERASE SMYD4 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;histone deacetylase binding#GO:0042826 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;heart development#GO:0007507 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000017013.3|UniProtKB=G3RLG0 G3RLG0 ERICH6 PTHR23093:SF11 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 GLUTAMATE-RICH PROTEIN 6 GORGO|Ensembl=ENSGGOG00000005680.3|UniProtKB=G3QSC6 G3QSC6 GPR148 PTHR26451:SF928 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G PROTEIN-COUPLED RECEPTOR 148-RELATED binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000012422.3|UniProtKB=G3R9N1 G3R9N1 GDF3 PTHR11848:SF38 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 3 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000002887.3|UniProtKB=G3QK67 G3QK67 CCL13 PTHR12015:SF147 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 13 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677 positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;cell migration#GO:0016477;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;cell communication#GO:0007154;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;taxis#GO:0042330;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;response to peptide#GO:1901652;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;positive regulation of cell motility#GO:2000147;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000010724.3|UniProtKB=G3R586 G3R586 OGFRL1 PTHR14015:SF0 OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR OPIOID GROWTH FACTOR RECEPTOR-LIKE PROTEIN 1 transmembrane signal receptor#PC00197 GORGO|Gene=TAS1R3|UniProtKB=Q717C1 Q717C1 TAS1R3 PTHR24061:SF435 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 3 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000015021.3|UniProtKB=G3RGB7 G3RGB7 SLC25A18 PTHR45678:SF11 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED MITOCHONDRIAL GLUTAMATE CARRIER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000025469.2|UniProtKB=A0A2I2Z7C0 A0A2I2Z7C0 PTHR45633:SF17 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of immune system process#GO:0002684;organelle organization#GO:0006996;gene expression#GO:0010467;protein maturation#GO:0051604;positive regulation of macromolecule metabolic process#GO:0010604;lymphocyte activation#GO:0046649;cellular component organization or biogenesis#GO:0071840;positive regulation of multicellular organismal process#GO:0051240;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular localization#GO:0051641;positive regulation of macromolecule biosynthetic process#GO:0010557;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;transport#GO:0006810;intracellular transport#GO:0046907;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;positive regulation of type I interferon production#GO:0032481;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;cellular response to topologically incorrect protein#GO:0035967;positive regulation of lymphocyte activation#GO:0051251;response to stress#GO:0006950;positive regulation of cell-cell adhesion#GO:0022409;apoptotic mitochondrial changes#GO:0008637;regulation of multicellular organismal process#GO:0051239;mitochondrion organization#GO:0007005;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;positive regulation of leukocyte activation#GO:0002696;metabolic process#GO:0008152;regulation of cell activation#GO:0050865;T cell activation#GO:0042110;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;response to unfolded protein#GO:0006986;regulation of macromolecule biosynthetic process#GO:0010556;mitochondrial protein import pathway#GO:7770058;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;establishment of localization#GO:0051234;cell death#GO:0008219;positive regulation of cell adhesion#GO:0045785;leukocyte activation#GO:0045321;positive regulation of cytokine production#GO:0001819;cell activation#GO:0001775;cellular response to unfolded protein#GO:0034620;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179 organelle membrane#GO:0031090;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000013294.3|UniProtKB=A0A2I2YB49 A0A2I2YB49 SAMD1 PTHR24353:SF162 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 renal system process#GO:0003014;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;system process#GO:0003008;renal absorption#GO:0070293;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;CCKR signaling map#P06959>PKA-Calpha/beta/gamma#P07099;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;GABA-B receptor II signaling#P05731>PKA#P05752;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Endothelin signaling pathway#P00019>PKA#P00570;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Nicotine pharmacodynamics pathway#P06587>PRKACA#P06588 GORGO|Ensembl=ENSGGOG00000015648.3|UniProtKB=A0A2I2ZKP6 A0A2I2ZKP6 TDG PTHR12159:SF9 G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA glycosylase#PC00010;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000010030.3|UniProtKB=G3R3G2 G3R3G2 C4H5orf52 PTHR35666:SF1 SIMILAR TO RIKEN CDNA 4921536K21 SIMILAR TO HUMAN CHROMOSOME 5 OPEN READING FRAME 52 GORGO|Ensembl=ENSGGOG00000008179.3|UniProtKB=G3QYR2 G3QYR2 ARMC2 PTHR21356:SF2 ARMADILLO REPEAT CONTAINING 2 ARMADILLO REPEAT-CONTAINING PROTEIN 2 cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232 GORGO|Ensembl=ENSGGOG00000011438.3|UniProtKB=G3RWI1 G3RWI1 UGT2B4 PTHR48043:SF164 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2B4 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020 regulation of biological quality#GO:0065008;estrogen metabolic process#GO:0008210;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;primary metabolic process#GO:0044238 GORGO|Ensembl=ENSGGOG00000002247.3|UniProtKB=A0A2I2ZUS6 A0A2I2ZUS6 LOC101147312 PTHR48099:SF2 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058;metabolic process#GO:0008152;tetrahydrofolate biosynthetic process#GO:0046654;tetrahydrofolate metabolic process#GO:0046653 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010041.3|UniProtKB=G3R3K3 G3R3K3 COL22A1 PTHR24023:SF845 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXII) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000039898.1|UniProtKB=A0A2I2Z6V6 A0A2I2Z6V6 LCLAT1 PTHR10983:SF81 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED LYSOCARDIOLIPIN ACYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000012920.3|UniProtKB=A0A2I2YBV6 A0A2I2YBV6 PRRG3 PTHR24278:SF39 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 3 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000036841.1|UniProtKB=A0A2I2ZRQ4 A0A2I2ZRQ4 PTHR23115:SF222 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 1-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000016407.3|UniProtKB=G3RJW0 G3RJW0 SLC30A2 PTHR11562:SF51 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A2 metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385 response to metal ion#GO:0010038;transport#GO:0006810;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;response to chemical#GO:0042221;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;metal ion transport#GO:0030001;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000038037.1|UniProtKB=A0A2I2Y2Y7 A0A2I2Y2Y7 HP1BP3 PTHR15832:SF1 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG HETEROCHROMATIN PROTEIN 1-BINDING PROTEIN 3 DNA binding#GO:0003677;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037528.1|UniProtKB=A0A2I2Z2G5 A0A2I2Z2G5 PTHR10971:SF29 MRNA EXPORT FACTOR AND BUB3 SUBFAMILY NOT NAMED ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of cell cycle#GO:0045786;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;negative regulation of chromosome segregation#GO:0051985;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic nuclear division#GO:0007088;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251 chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;kinetochore#GO:0000776;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000024629.2|UniProtKB=G3S540 G3S540 MRPL13 PTHR11545:SF45 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of translation#GO:0017148;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016016.3|UniProtKB=G3S799 G3S799 PTHR46024:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE SETDB2 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000015626.3|UniProtKB=G3RHX2 G3RHX2 USP36 PTHR24006:SF653 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36 cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;regulation of protein stability#GO:0031647;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000008544.3|UniProtKB=G3S1I3 G3S1I3 EYA3 PTHR10190:SF5 EYES ABSENT PROTEIN PHOSPHATASE EYA3 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of response to stress#GO:0080134;developmental process#GO:0032502;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;positive regulation of DNA metabolic process#GO:0051054;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000009698.3|UniProtKB=G3R2L7 G3R2L7 AP1AR PTHR34529:SF1 AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 Golgi to endosome transport#GO:0006895;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;transport vesicle#GO:0030133;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003134.3|UniProtKB=G3QKU7 G3QKU7 KRT74 PTHR45616:SF5 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 74 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;skin development#GO:0043588;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;developmental process#GO:0032502;epidermis development#GO:0008544;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513 supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015203.3|UniProtKB=G3RGT1 G3RGT1 ZDHHC9 PTHR22883:SF71 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC9 catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000022969.2|UniProtKB=G3SF77 G3SF77 ZNF287 PTHR23226:SF194 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 287 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000021980.2|UniProtKB=G3SI07 G3SI07 LOC101127907 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000037129.1|UniProtKB=A0A2I2ZC29 A0A2I2ZC29 DCUN1D3 PTHR12281:SF31 RP42 RELATED DCN1-LIKE PROTEIN 3 acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of protein modification process#GO:0031399;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of protein modification by small protein conjugation or removal#GO:1903320 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000022382.2|UniProtKB=G3SK75 G3SK75 N6AMT1 PTHR45875:SF3 METHYLTRANSFERASE N6AMT1 METHYLTRANSFERASE HEMK2 catalytic activity#GO:0003824;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;methyltransferase complex#GO:0034708;transferase complex#GO:1990234;catalytic complex#GO:1902494 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000000945.3|UniProtKB=G3QF67 G3QF67 ENG PTHR14002:SF1 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ENDOGLIN molecular transducer activity#GO:0060089;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;cytokine binding#GO:0019955;transforming growth factor beta binding#GO:0050431;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;cytokine receptor binding#GO:0005126;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;transforming growth factor beta receptor activity#GO:0005024;kinase activity#GO:0016301 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;vasculogenesis#GO:0001570;cell surface receptor signaling pathway#GO:0007166;mesenchymal cell differentiation#GO:0048762;vasculature development#GO:0001944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular response to transforming growth factor beta stimulus#GO:0071560;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to transforming growth factor beta#GO:0071559;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;tube development#GO:0035295;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;mesenchyme development#GO:0060485;cellular developmental process#GO:0048869 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007252.3|UniProtKB=G3QWE3 G3QWE3 ATG4C PTHR22624:SF38 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4C hydrolase activity#GO:0016787;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;autophagy#GO:0006914;autophagosome organization#GO:1905037;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;biosynthetic process#GO:0009058;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000006047.3|UniProtKB=G3QTA4 G3QTA4 PTHR47011:SF1 CD226 ANTIGEN CD226 ANTIGEN cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of signaling#GO:0023056;regulation of immune effector process#GO:0002697;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of adaptive immune response#GO:0002821;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of immune effector process#GO:0002699 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000008979.3|UniProtKB=A0A2I2YS00 A0A2I2YS00 STN1 PTHR13989:SF58 REPLICATION PROTEIN A-RELATED CST COMPLEX SUBUNIT STN1 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162 nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance via telomere lengthening#GO:0010833;cellular process#GO:0009987;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;nuclear telomere cap complex#GO:0000783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000024615.2|UniProtKB=G3RTB3 G3RTB3 TXNDC9 PTHR21148:SF11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000002204.3|UniProtKB=G3QIG1 G3QIG1 SLC17A4 PTHR11662:SF284 SOLUTE CARRIER FAMILY 17 SMALL INTESTINE URATE EXPORTER-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 inorganic anion transport#GO:0015698;phosphate ion transport#GO:0006817;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000014567.3|UniProtKB=G3RF45 G3RF45 C5H6orf15 PTHR15817:SF2 STG PROTEIN SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 15 GORGO|Ensembl=ENSGGOG00000000138.3|UniProtKB=G3QD33 G3QD33 PTHR24025:SF9 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-1 metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000000972.3|UniProtKB=G3QF91 G3QF91 KCNS3 PTHR11537:SF39 VOLTAGE-GATED POTASSIUM CHANNEL DELAYED-RECTIFIER POTASSIUM CHANNEL REGULATORY SUBUNIT KCNS3 ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 action potential#GO:0001508;metal ion transport#GO:0030001;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000002604.3|UniProtKB=G3SCI3 G3SCI3 UGT1A6 PTHR48050:SF12 STEROL 3-BETA-GLUCOSYLTRANSFERASE UDP-GLUCURONOSYLTRANSFERASE 1A3-RELATED molecular function regulator activity#GO:0098772;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;enzyme inhibitor activity#GO:0004857;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;enzyme binding#GO:0019899;binding#GO:0005488 response to endogenous stimulus#GO:0009719;regulation of hormone levels#GO:0010817;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;liver development#GO:0001889;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;response to hormone#GO:0009725;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;steroid metabolic process#GO:0008202;metabolic process#GO:0008152;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular response to steroid hormone stimulus#GO:0071383;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to steroid hormone#GO:0048545;anatomical structure development#GO:0048856;system development#GO:0048731;pigment metabolic process#GO:0042440;hormone metabolic process#GO:0042445;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;developmental process#GO:0032502;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220 Nicotine degradation#P05914>UGT1A4#P05982 GORGO|Ensembl=ENSGGOG00000037436.1|UniProtKB=A0A2I2YWY8 A0A2I2YWY8 SERPINB11 PTHR11461:SF199 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B11 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000008462.3|UniProtKB=G3QZL1 G3QZL1 LAMA5 PTHR10574:SF448 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-5 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;neuron differentiation#GO:0030182;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000015370.3|UniProtKB=G3RH81 G3RH81 LONP1 PTHR43718:SF2 LON PROTEASE LON PROTEASE HOMOLOG, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;mitochondrion organization#GO:0007005;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000011993.3|UniProtKB=G3R8K3 G3R8K3 GRM6 PTHR24060:SF24 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 6 transmembrane signaling receptor activity#GO:0004888;glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;glutamate receptor signaling pathway#GO:0007215;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044 GORGO|Ensembl=ENSGGOG00000012328.3|UniProtKB=G3S0L5 G3S0L5 PDP2 PTHR13832:SF343 PROTEIN PHOSPHATASE 2C [PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000040900.1|UniProtKB=A0A2I2YAN8 A0A2I2YAN8 SUB1 PTHR13215:SF0 RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000007820.3|UniProtKB=G3QXT4 G3QXT4 RHOF PTHR24072:SF99 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOF ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265 cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell migration#GO:0016477;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000001102.4|UniProtKB=G3QFL0 G3QFL0 NR3C2 PTHR48092:SF19 KNIRPS-RELATED PROTEIN-RELATED MINERALOCORTICOID RECEPTOR transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;sequence-specific double-stranded DNA binding#GO:1990837 intracellular receptor signaling pathway#GO:0030522;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;steroid hormone receptor signaling pathway#GO:0043401;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;response to steroid hormone#GO:0048545;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;cellular response to steroid hormone stimulus#GO:0071383 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000043199.1|UniProtKB=A0A2I2YLF2 A0A2I2YLF2 INSYN1 PTHR15917:SF3 FAMILY NOT NAMED INHIBITORY SYNAPTIC FACTOR 1 anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission, postsynaptic#GO:0099565;chemical synaptic transmission#GO:0007268;regulation of postsynaptic membrane potential#GO:0060078;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of biological quality#GO:0065008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;system process#GO:0003008;cell surface receptor signaling pathway#GO:0007166 organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;cell junction#GO:0030054;postsynaptic density#GO:0014069 GORGO|Ensembl=ENSGGOG00000005144.3|UniProtKB=A0A2I2YGK6 A0A2I2YGK6 LPCAT2 PTHR23063:SF21 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE 2 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000022326.2|UniProtKB=G3S2N5 G3S2N5 PTHR19343:SF27 T CELL RECEPTOR ALPHA VARIABLE 1-2 IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000042527.1|UniProtKB=G3SJW2 G3SJW2 PTHR11489:SF17 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2-RELATED structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003523.3|UniProtKB=G3QLV3 G3QLV3 TECPR2 PTHR23287:SF16 RUBY-EYE2-LIKE PROTEIN TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000015195.3|UniProtKB=G3RGS2 G3RGS2 LOC101153190 PTHR19304:SF10 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-7 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302 GORGO|Ensembl=ENSGGOG00000013519.4|UniProtKB=G3RCF8 G3RCF8 ARHGAP18 PTHR14963:SF6 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 18 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000000753.3|UniProtKB=A0A2I2YZ82 A0A2I2YZ82 LOC101151856 PTHR23149:SF9 G PATCH DOMAIN CONTAINING PROTEIN G PATCH DOMAIN-CONTAINING PROTEIN 4 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013336.3|UniProtKB=G3RBZ8 G3RBZ8 TNN PTHR19143:SF348 FIBRINOGEN/TENASCIN/ANGIOPOEITIN TENASCIN-N cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515 plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental growth#GO:0048589;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;developmental cell growth#GO:0048588;system development#GO:0048731;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;cell growth#GO:0016049;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;developmental growth involved in morphogenesis#GO:0060560;neuron projection extension#GO:1990138;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000027662.2|UniProtKB=G3S2Z8 G3S2Z8 POU5F1 PTHR11636:SF86 POU DOMAIN POU DOMAIN, CLASS 5, TRANSCRIPTION FACTOR 1-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000028236.2|UniProtKB=G3SD31 G3SD31 SPICE1 PTHR31167:SF3 SPINDLE AND CENTRIOLE ASSOCIATED PROTEIN 1 SPICE1 SPINDLE AND CENTRIOLE-ASSOCIATED PROTEIN 1 microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;localization#GO:0051179;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640;organelle assembly#GO:0070925;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;spindle organization#GO:0007051;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;biological regulation#GO:0065007;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;regulation of organelle assembly#GO:1902115;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000009175.3|UniProtKB=G3R1A5 G3R1A5 GLRX PTHR46185:SF1 GLUTAREDOXIN-1 GLUTAREDOXIN-1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000009420.3|UniProtKB=A0A2I2ZX76 A0A2I2ZX76 MCTS1 PTHR22798:SF10 MCT-1 PROTEIN MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1 translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000042182.1|UniProtKB=G3S5G6 G3S5G6 PTHR23266:SF400 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-9 binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000010868.3|UniProtKB=G3R5L3 G3R5L3 TAFA4 PTHR31770:SF11 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-4 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;leukocyte migration#GO:0050900;phagocytosis#GO:0006909;transport#GO:0006810;response to stimulus#GO:0050896;cell motility#GO:0048870;endocytosis#GO:0006897;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;localization#GO:0051179;macrophage chemotaxis#GO:0048246;cell chemotaxis#GO:0060326;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;mononuclear cell migration#GO:0071674;chemotaxis#GO:0006935 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chemokine#PC00074;cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000000697.3|UniProtKB=G3QEI9 G3QEI9 YIPF2 PTHR12822:SF3 PROTEIN YIPF PROTEIN YIPF2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000000785.3|UniProtKB=G3QES5 G3QES5 PTHR12349:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC8 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 regulation of transport#GO:0051049;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000000620.3|UniProtKB=G3QEB9 G3QEB9 ABCG5 PTHR48041:SF113 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 5 lipid transfer activity#GO:0120013;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;cholesterol transfer activity#GO:0120020;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;transmembrane transporter activity#GO:0022857 lipid transport#GO:0006869;cholesterol efflux#GO:0033344;cellular process#GO:0009987;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;sterol transport#GO:0015918;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;transport#GO:0006810;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;localization#GO:0051179;lipid localization#GO:0010876 plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;membrane#GO:0016020;ATP-binding cassette (ABC) transporter complex#GO:0043190;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533;apical part of cell#GO:0045177 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024208.2|UniProtKB=G3SHI9 G3SHI9 SBK3 PTHR24363:SF6 SERINE/THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000043647.1|UniProtKB=A0A2I2YTK4 A0A2I2YTK4 ZBTB5 PTHR24394:SF17 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 5 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity#GO:0001217 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007177.3|UniProtKB=G3RQA6 G3RQA6 ZNF219 PTHR45925:SF1 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 219 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009951.3|UniProtKB=A0A2I2Y817 A0A2I2Y817 ARHGEF26 PTHR12845:SF4 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 26 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of actin filament-based process#GO:0032970;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000036271.1|UniProtKB=A0A2I2ZJX6 A0A2I2ZJX6 EIF4EBP2 PTHR12669:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 2 binding#GO:0005488;translation initiation factor binding#GO:0031369;protein binding#GO:0005515;translation regulator activity#GO:0045182 regulation of biological quality#GO:0065008;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;regulation of signaling#GO:0023051;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of synaptic plasticity#GO:0048167;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605 translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000002603.3|UniProtKB=G3RTT2 G3RTT2 P3H3 PTHR14049:SF14 LEPRECAN 1 PROLYL 3-HYDROXYLASE 3 catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular process#GO:0009987;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000026299.2|UniProtKB=G3SAR7 G3SAR7 RPS15A PTHR11758:SF13 40S RIBOSOMAL PROTEIN S15A SMALL RIBOSOMAL SUBUNIT PROTEIN US8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Gene=1A04_GORGO|UniProtKB=P30378 P30378 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN protein binding#GO:0005515;peptide binding#GO:0042277;antigen binding#GO:0003823;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000028454.2|UniProtKB=G3RS04 G3RS04 LOC101129329 PTHR19269:SF70 TROPOMYOSIN TROPOMYOSIN ALPHA-4 CHAIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 organelle organization#GO:0006996;cellular component organization#GO:0016043;muscle system process#GO:0003012;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;muscle contraction#GO:0006936;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;system process#GO:0003008 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000024850.2|UniProtKB=A0A2I2ZY61 A0A2I2ZY61 SRSF12 PTHR23147:SF3 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 12 intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000038677.1|UniProtKB=G3QL74 G3QL74 MYL6 PTHR23048:SF43 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT POLYPEPTIDE 6 catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;structural molecule activity#GO:0005198;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000008464.3|UniProtKB=G3QZG8 G3QZG8 DRC7 PTHR35249:SF2 DYNEIN REGULATORY COMPLEX SUBUNIT 7 DYNEIN REGULATORY COMPLEX SUBUNIT 7 reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;sperm motility#GO:0097722;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;flagellated sperm motility#GO:0030317 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000023384.2|UniProtKB=A0A2I2YBD5 A0A2I2YBD5 LOC101146765 PTHR15081:SF1 NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED NUCLEAR AUTOANTIGENIC SPERM PROTEIN histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382;cellular component organization or biogenesis#GO:0071840;kinetochore organization#GO:0051383;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000009140.3|UniProtKB=G3R179 G3R179 CD7 PTHR15343:SF0 CD7 T-CELL ANTIGEN CD7 GORGO|Ensembl=ENSGGOG00000004200.3|UniProtKB=G3QNK2 G3QNK2 ALG2 PTHR45918:SF1 ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2 ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001727.3|UniProtKB=G3QH80 G3QH80 LRRC32 PTHR45617:SF4 LEUCINE RICH REPEAT FAMILY PROTEIN TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC32 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016160.3|UniProtKB=G3S980 G3S980 FIRRM PTHR16071:SF2 CHROMOSOME 1 OPEN READING FRAME 112 FIGNL1-INTERACTING REGULATOR OF RECOMBINATION AND MITOSIS GORGO|Ensembl=ENSGGOG00000004879.3|UniProtKB=G3QQB6 G3QQB6 NDFIP1 PTHR13396:SF3 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY-INTERACTING PROTEIN 1 protein metabolic process#GO:0019538;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of protein modification by small protein conjugation or removal#GO:1903320;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of protein modification process#GO:0031399;macromolecule metabolic process#GO:0043170;regulation of protein ubiquitination#GO:0031396;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;biological regulation#GO:0065007;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000010082.3|UniProtKB=G3R3K7 G3R3K7 PPM1A PTHR47992:SF121 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1A phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000036756.1|UniProtKB=A0A2I2Z5S9 A0A2I2Z5S9 STARD7 PTHR19308:SF8 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 7, MITOCHONDRIAL GORGO|Ensembl=ENSGGOG00000012841.3|UniProtKB=G3RAR0 G3RAR0 PTHR10799:SF819 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 1 DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;heterochromatin organization#GO:0070828;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000016733.3|UniProtKB=A0A2I2YDX7 A0A2I2YDX7 CRYBG1 PTHR11818:SF2 BETA/GAMMA CRYSTALLIN BETA_GAMMA CRYSTALLIN DOMAIN-CONTAINING PROTEIN 1 structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;sensory system development#GO:0048880;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000013275.3|UniProtKB=G3RBT4 G3RBT4 DYNLT2B PTHR21255:SF7 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000003841.3|UniProtKB=G3QMM8 G3QMM8 LOC101141204 PTHR26453:SF18 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T2-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013312.3|UniProtKB=G3RBX8 G3RBX8 RBM27 PTHR14398:SF1 RNA RECOGNITION RRM/RNP DOMAIN RNA-BINDING PROTEIN 27 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000034880.2|UniProtKB=G3SKD6 G3SKD6 SCAI PTHR21243:SF21 PROTEIN SCAI PROTEIN SCAI transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000008586.3|UniProtKB=A0A2I2ZVS0 A0A2I2ZVS0 PTHR26450:SF53 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51H1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011365.3|UniProtKB=G3R6W3 G3R6W3 PKN3 PTHR24356:SF318 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N3 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 GORGO|Ensembl=ENSGGOG00000014001.3|UniProtKB=G3RDP6 G3RDP6 AKAP17A PTHR12484:SF2 B-LYMPHOCYTE ANTIGEN-RELATED A-KINASE ANCHOR PROTEIN 17A binding#GO:0005488;protein kinase A binding#GO:0051018;protein binding#GO:0005515 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000023946.2|UniProtKB=G3RM28 G3RM28 LOC115931834 PTHR39653:SF6 KERATIN-ASSOCIATED PROTEIN 20-2 KERATIN-ASSOCIATED PROTEIN 20-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000005511.3|UniProtKB=G3QRX9 G3QRX9 ZC3H12D PTHR12876:SF11 N4BP1-RELATED RIBONUCLEASE ZC3H12D-RELATED RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000011204.4|UniProtKB=G3R6H1 G3R6H1 SEH1L PTHR11024:SF3 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER NUCLEOPORIN SEH1 regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;cellular response to amino acid starvation#GO:0034198;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;response to stress#GO:0006950;positive regulation of TORC1 signaling#GO:1904263;response to nutrient levels#GO:0031667;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;cellular response to starvation#GO:0009267 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;nuclear protein-containing complex#GO:0140513;Seh1-associated complex#GO:0035859;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002977.3|UniProtKB=G3QKF4 G3QKF4 NCAN PTHR22804:SF24 AGGRECAN/VERSICAN PROTEOGLYCAN NEUROCAN CORE PROTEIN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012;cell periphery#GO:0071944;cell junction#GO:0030054;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000001116.3|UniProtKB=G3QFM4 G3QFM4 SLC7A3 PTHR43243:SF20 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000013197.3|UniProtKB=A0A2I2YIX1 A0A2I2YIX1 NTM PTHR42757:SF9 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED NEUROTRIMIN regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;cell adhesion#GO:0007155;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007 postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;presynaptic active zone membrane#GO:0048787;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000010677.3|UniProtKB=A0A2I2ZQ01 A0A2I2ZQ01 BTF3L4 PTHR10351:SF29 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 HOMOLOG 4 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000002797.3|UniProtKB=G3QJZ2 G3QJZ2 KCNS2 PTHR11537:SF60 VOLTAGE-GATED POTASSIUM CHANNEL DELAYED-RECTIFIER POTASSIUM CHANNEL REGULATORY SUBUNIT KCNS2 potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;metal ion transport#GO:0030001;action potential#GO:0001508;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;cellular process#GO:0009987 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000011055.3|UniProtKB=G3R638 G3R638 ALKBH1 PTHR16557:SF12 ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED NUCLEIC ACID DIOXYGENASE ALKBH1 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;demethylase activity#GO:0032451;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;metal ion binding#GO:0046872;binding#GO:0005488;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;cation binding#GO:0043169;dioxygenase activity#GO:0051213;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094 cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;RNA modification#GO:0009451;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000010170.3|UniProtKB=G3R3T9 G3R3T9 WARS1 PTHR10055:SF1 TRYPTOPHANYL-TRNA SYNTHETASE TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000010823.3|UniProtKB=G3R5I4 G3R5I4 ME2 PTHR23406:SF27 MALIC ENZYME-RELATED NAD-DEPENDENT MALIC ENZYME, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000006780.3|UniProtKB=G3QV69 G3QV69 TAL2 PTHR13864:SF21 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000007638.3|UniProtKB=Q8WMW2 Q8WMW2 RHBG PTHR11730:SF42 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE B channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 GORGO|Gene=COX5A|UniProtKB=B0VYX3 B0VYX3 COX5A PTHR14200:SF16 CYTOCHROME C OXIDASE POLYPEPTIDE CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 oxidase#PC00175;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000009126.3|UniProtKB=G3S673 G3S673 ZCCHC17 PTHR15838:SF1 NUCLEOLAR PROTEIN OF 40 KDA ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 17 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;RNA stabilization#GO:0043489;negative regulation of catabolic process#GO:0009895;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 GORGO|Ensembl=ENSGGOG00000001849.3|UniProtKB=G3QHJ4 G3QHJ4 PTHR12241:SF31 TUBULIN POLYGLUTAMYLASE POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1 protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631 cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;organelle assembly#GO:0070925;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288 cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000007990.3|UniProtKB=G3QY79 G3QY79 DHH PTHR11889:SF56 HEDGEHOG DESERT HEDGEHOG PROTEIN ion binding#GO:0043167;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell fate specification#GO:0001708;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cell fate commitment#GO:0045165;smoothened signaling pathway#GO:0007224;cell communication#GO:0007154;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000041003.1|UniProtKB=A0A2I2YQU0 A0A2I2YQU0 PTHR46257:SF1 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;hydrolase activity#GO:0016787;binding#GO:0005488 mitotic cell cycle#GO:0000278;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;cell cycle#GO:0007049;developmental process#GO:0032502;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>SHP2#P00647;Interferon-gamma signaling pathway#P00035>PTP#P00960;Angiogenesis#P00005>SHP2#P00181 GORGO|Ensembl=ENSGGOG00000003687.3|UniProtKB=G3QM92 G3QM92 MAP2K1 PTHR47448:SF2 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000015049.3|UniProtKB=G3RGE1 G3RGE1 OR7A10 PTHR26453:SF626 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000036469.1|UniProtKB=G3SC60 G3SC60 PTHR23267:SF323 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-60 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000082.3|UniProtKB=G3QCY0 G3QCY0 EPHA1 PTHR24416:SF28 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000042033.1|UniProtKB=A0A2I2ZV78 A0A2I2ZV78 PTHR45633:SF19 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 primary metabolic process#GO:0044238;positive regulation of type I interferon production#GO:0032481;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;cellular response to topologically incorrect protein#GO:0035967;positive regulation of lymphocyte activation#GO:0051251;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;positive regulation of multicellular organismal process#GO:0051240;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;immune system process#GO:0002376;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular localization#GO:0051641;organelle organization#GO:0006996;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lymphocyte activation#GO:0046649;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component organization or biogenesis#GO:0071840;leukocyte activation#GO:0045321;cell death#GO:0008219;positive regulation of cell adhesion#GO:0045785;positive regulation of cytokine production#GO:0001819;cellular response to unfolded protein#GO:0034620;cell activation#GO:0001775;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;regulation of macromolecule biosynthetic process#GO:0010556;mitochondrial protein import pathway#GO:7770058;regulation of leukocyte cell-cell adhesion#GO:1903037;establishment of localization#GO:0051234;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;cellular component organization#GO:0016043;regulation of cell activation#GO:0050865;regulation of lymphocyte activation#GO:0051249;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;response to unfolded protein#GO:0006986;positive regulation of cell-cell adhesion#GO:0022409;response to stress#GO:0006950;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;regulation of multicellular organismal process#GO:0051239;metabolic process#GO:0008152;positive regulation of leukocyte activation#GO:0002696 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000009321.3|UniProtKB=G3R1M9 G3R1M9 NSUN6 PTHR22807:SF34 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(72)-C(5))-METHYLTRANSFERASE NSUN6 catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 rRNA base methylation#GO:0070475;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;tRNA metabolic process#GO:0006399;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;ribonucleoprotein complex biogenesis#GO:0022613;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;macromolecule modification#GO:0043412 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005238.3|UniProtKB=A0A2I2ZLK2 A0A2I2ZLK2 MYSM1 PTHR12802:SF189 SWI/SNF COMPLEX-RELATED DEUBIQUITINASE MYSM1 histone binding#GO:0042393;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;transcription coactivator activity#GO:0003713;protein binding#GO:0005515 chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000005116.4|UniProtKB=G3QQY8 G3QQY8 TBCK PTHR24345:SF87 SERINE/THREONINE-PROTEIN KINASE PLK TBC DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000024851.2|UniProtKB=G3SD40 G3SD40 GRB14 PTHR11243:SF22 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Grb14#P00197 GORGO|Ensembl=ENSGGOG00000027328.2|UniProtKB=G3RVZ7 G3RVZ7 LOC101147670 PTHR24040:SF10 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN VITAMIN K-DEPENDENT PROTEIN S biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of coagulation#GO:0050818;negative regulation of coagulation#GO:0050819;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000041775.1|UniProtKB=A0A2I2Y350 A0A2I2Y350 CPD PTHR11532:SF73 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 GORGO|Ensembl=ENSGGOG00000044218.1|UniProtKB=A0A2I2ZMH9 A0A2I2ZMH9 NEK7 PTHR43289:SF2 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;positive regulation of response to external stimulus#GO:0032103;positive regulation of cellular component biogenesis#GO:0044089;regulation of response to external stimulus#GO:0032101;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000043577.1|UniProtKB=A0A2I2ZUX8 A0A2I2ZUX8 LOC129524593 PTHR11430:SF120 LIPOCALIN LIPOCALIN_CYTOSOLIC FATTY-ACID BINDING DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000008623.3|UniProtKB=G3QZW0 G3QZW0 SLC41A2 PTHR16228:SF25 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000041211.1|UniProtKB=A0A2I2ZIF7 A0A2I2ZIF7 CELF5 PTHR24012:SF728 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 5 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036936.1|UniProtKB=A0A2I2YMV4 A0A2I2YMV4 PRDM6 PTHR16515:SF22 PR DOMAIN ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM6-RELATED biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Gene=RHLC_GORGO|UniProtKB=Q28426 Q28426 PTHR11730:SF100 AMMONIUM TRANSPORTER BLOOD GROUP RH(CE) POLYPEPTIDE transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;transport#GO:0006810;homeostatic process#GO:0042592;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024565.2|UniProtKB=G3SEQ2 G3SEQ2 ADGRF1 PTHR45813:SF3 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;synapse organization#GO:0050808;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;neuron differentiation#GO:0030182;cellular component assembly#GO:0022607;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;generation of neurons#GO:0048699;synapse assembly#GO:0007416;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000005811.3|UniProtKB=G3QSQ6 G3QSQ6 GIGYF1 PTHR14445:SF37 GRB10 INTERACTING GYF PROTEIN GRB10-INTERACTING GYF PROTEIN 1 translation regulator activity#GO:0045182 cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000006478.3|UniProtKB=G3QUD5 G3QUD5 CYTIP PTHR15963:SF1 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED CYTOHESIN-INTERACTING PROTEIN regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000012081.3|UniProtKB=G3R8S4 G3R8S4 AADAT PTHR42790:SF24 AMINOTRANSFERASE KYNURENINE_ALPHA-AMINOADIPATE AMINOTRANSFERASE, MITOCHONDRIAL transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000006178.3|UniProtKB=A0A2I2YSU4 A0A2I2YSU4 ARL9 PTHR46724:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9 GORGO|Ensembl=ENSGGOG00000024914.2|UniProtKB=G3S436 G3S436 SLC16A5 PTHR11360:SF21 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 6 monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000027525.2|UniProtKB=A0A2I2ZPL5 A0A2I2ZPL5 DKK2 PTHR12113:SF12 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 2 binding#GO:0005488;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 negative regulation of cell communication#GO:0010648;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical Wnt signaling pathway#GO:0060828 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000004032.3|UniProtKB=G3RQV4 G3RQV4 HVCN1 PTHR46480:SF1 F20B24.22 VOLTAGE-GATED HYDROGEN CHANNEL 1 voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;voltage-gated monoatomic cation channel activity#GO:0022843 transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000028186.2|UniProtKB=A0A2I2Y296 A0A2I2Y296 SCOC PTHR21614:SF0 SHORT COILED COIL PROTEIN SHORT COILED-COIL PROTEIN Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 GORGO|Gene=RHLD_GORGO|UniProtKB=Q28427 Q28427 PTHR11730:SF43 AMMONIUM TRANSPORTER BLOOD GROUP RH(D) POLYPEPTIDE passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;transport#GO:0006810;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000007921.3|UniProtKB=G3S4L5 G3S4L5 FER1L4 PTHR12546:SF36 FER-1-LIKE FER-1-LIKE PROTEIN 4 cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000040847.1|UniProtKB=A0A2I2YWY4 A0A2I2YWY4 LOC129529551 PTHR13282:SF9 PROTEIN FAM32A SUBFAMILY NOT NAMED membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000014528.3|UniProtKB=G3RF23 G3RF23 CENPJ PTHR10331:SF23 T COMPLEX PROTEIN 10 CENTROSOMAL P4.1-ASSOCIATED PROTEIN protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 centriole replication#GO:0007099;organelle assembly#GO:0070925;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell cycle#GO:0007049;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000017189.3|UniProtKB=G3RLW3 G3RLW3 SLFNL1 PTHR12155:SF29 SCHLAFEN SCHLAFEN-LIKE PROTEIN 1 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000016590.3|UniProtKB=G3S9Z3 G3S9Z3 HPS3 PTHR28633:SF1 HERMANSKY-PUDLAK SYNDROME 3 PROTEIN BLOC-2 COMPLEX MEMBER HPS3 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000001589.3|UniProtKB=G3QGV3 G3QGV3 CETP PTHR47616:SF1 CHOLESTERYL ESTER TRANSFER PROTEIN CHOLESTERYL ESTER TRANSFER PROTEIN phosphatidylcholine binding#GO:0031210;steroid binding#GO:0005496;alcohol binding#GO:0043178;phospholipid binding#GO:0005543;cholesterol binding#GO:0015485;lipid binding#GO:0008289;cation binding#GO:0043169;ion binding#GO:0043167;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094 neutral lipid metabolic process#GO:0006638;sterol metabolic process#GO:0016125;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;acylglycerol metabolic process#GO:0006639;transport#GO:0006810;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;lipid transport#GO:0006869;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;macromolecule localization#GO:0033036;localization#GO:0051179;triglyceride homeostasis#GO:0070328;phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;chemical homeostasis#GO:0048878;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;steroid metabolic process#GO:0008202;cellular process#GO:0009987;lipid localization#GO:0010876;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;secondary alcohol metabolic process#GO:1902652;cellular component organization#GO:0016043;lipid homeostasis#GO:0055088;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;protein-lipid complex#GO:0032994;extracellular protein-containing complex#GO:0140392;lipoprotein particle#GO:1990777;plasma lipoprotein particle#GO:0034358;high-density lipoprotein particle#GO:0034364 CCKR signaling map#P06959>CETP#P07189 GORGO|Ensembl=ENSGGOG00000038043.1|UniProtKB=G3SGR0 G3SGR0 LOC101126811 PTHR26453:SF619 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 10 SUBFAMILY J MEMBER 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016968.3|UniProtKB=A0A2I2ZIQ6 A0A2I2ZIQ6 NUMA1 PTHR18902:SF24 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED NUCLEAR MITOTIC APPARATUS PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;regulation of protein localization#GO:0032880;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;spindle localization#GO:0051653;cellular localization#GO:0051641;establishment of spindle localization#GO:0051293;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of localization#GO:0032879;mitotic cell cycle process#GO:1903047;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234 mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000013565.3|UniProtKB=G3RCK0 G3RCK0 MRPS15 PTHR46685:SF1 28S RIBOSOMAL PROTEIN S15, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US15M mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004947.3|UniProtKB=A0A2I2YV51 A0A2I2YV51 PANK3 PTHR12280:SF21 PANTOTHENATE KINASE PANTOTHENATE KINASE 3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 GORGO|Ensembl=ENSGGOG00000016696.3|UniProtKB=G3RWA3 G3RWA3 KAT2B PTHR45750:SF2 GH11602P HISTONE ACETYLTRANSFERASE KAT2B catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 p53 pathway#P00059>PCAF#P04629;Gonadotropin-releasing hormone receptor pathway#P06664>Pcaf#P06715 GORGO|Ensembl=ENSGGOG00000014055.3|UniProtKB=G3RDV1 G3RDV1 TPSG1 PTHR24253:SF170 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000014413.3|UniProtKB=G3SJ91 G3SJ91 LOC101134815 PTHR19944:SF68 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ BETA 2 CHAIN protein-containing complex binding#GO:0044877;binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;positive regulation of cell adhesion#GO:0045785;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;immune system process#GO:0002376;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of lymphocyte activation#GO:0051249 cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;late endosome membrane#GO:0031902;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000042468.1|UniProtKB=A0A2I2ZU43 A0A2I2ZU43 NFAM1 PTHR35680:SF1 NFAT ACTIVATION MOLECULE 1 NFAT ACTIVATION MOLECULE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 immune system process#GO:0002376;regulation of immune response#GO:0050776;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;calcium-mediated signaling#GO:0019722;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;intracellular signaling cassette#GO:0141124 cellular anatomical structure#GO:0110165;membrane microdomain#GO:0098857;membrane raft#GO:0045121;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000023906.2|UniProtKB=G3RYZ5 G3RYZ5 MAD2L1BP PTHR15681:SF1 MAD2L1-BINDING PROTEIN MAD2L1-BINDING PROTEIN nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000007709.3|UniProtKB=G3QXK4 G3QXK4 SDCCAG8 PTHR34343:SF1 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 multicellular organism development#GO:0007275;neuron migration#GO:0001764;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;microtubule organizing center organization#GO:0031023;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell migration#GO:0016477;cytoskeleton organization#GO:0007010;tube development#GO:0035295;nervous system development#GO:0007399;organelle organization#GO:0006996;cellular process#GO:0009987;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell motility#GO:0048870;cellular component organization#GO:0016043;establishment of cell polarity#GO:0030010;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239 microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000039009.1|UniProtKB=A0A2I2ZB30 A0A2I2ZB30 PTHR10639:SF27 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583 plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;membrane protein complex#GO:0098796;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;secretory vesicle#GO:0099503;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;cell junction#GO:0030054;clathrin vesicle coat#GO:0030125;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;synapse#GO:0045202;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;coated membrane#GO:0048475;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000003151.3|UniProtKB=G3QKW4 G3QKW4 TEKT3 PTHR19960:SF24 TEKTIN TEKTIN-3 cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;organelle assembly#GO:0070925;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782 9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000022562.2|UniProtKB=A0A2I2ZLD9 A0A2I2ZLD9 LOC101132366 PTHR43128:SF15 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 energy derivation by oxidation of organic compounds#GO:0015980;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000022320.2|UniProtKB=G3RPX8 G3RPX8 ITGA1 PTHR23220:SF22 INTEGRIN ALPHA INTEGRIN ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;integrin complex#GO:0008305 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941;Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820 GORGO|Ensembl=ENSGGOG00000023475.2|UniProtKB=G3RTI8 G3RTI8 LYPD2 PTHR16983:SF16 UPAR/LY6 DOMAIN-CONTAINING PROTEIN LY6_PLAUR DOMAIN CONTAINING 2-RELATED signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;acetylcholine receptor regulator activity#GO:0030548;binding#GO:0005488;signaling receptor binding#GO:0005102;acetylcholine receptor inhibitor activity#GO:0030550;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;neurotransmitter receptor regulator activity#GO:0099602;signaling receptor inhibitor activity#GO:0030547 response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000004073.3|UniProtKB=A0A2I2ZNI8 A0A2I2ZNI8 CYB561A3 PTHR10106:SF38 CYTOCHROME B561-RELATED LYSOSOMAL MEMBRANE ASCORBATE-DEPENDENT FERRIREDUCTASE CYB561A3 catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on metal ions#GO:0016722 carbohydrate homeostasis#GO:0033500;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;cytoplasm#GO:0005737;vacuole#GO:0005773 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000025362.2|UniProtKB=A0A2I2Z9W6 A0A2I2Z9W6 BLOC1S2 PTHR46479:SF1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 vesicle-mediated transport#GO:0016192;lysosome localization#GO:0032418;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;organelle localization#GO:0051640;intracellular transport#GO:0046907 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;BLOC-1 complex#GO:0031083;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000006087.3|UniProtKB=A0A2I2YEG1 A0A2I2YEG1 SLC27A2 PTHR43107:SF4 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 2 ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;catalytic activity#GO:0003824;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857 small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;lipid transport#GO:0006869;steroid metabolic process#GO:0008202;macromolecule localization#GO:0033036;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;lipid metabolic process#GO:0006629 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000040741.1|UniProtKB=A0A2I2YNR0 A0A2I2YNR0 HCAR1 PTHR46048:SF3 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007659.3|UniProtKB=A0A2I2YBM0 A0A2I2YBM0 SNX6 PTHR45850:SF4 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-6 cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037930.1|UniProtKB=A0A2I2YQ82 A0A2I2YQ82 HAPSTR2 PTHR31624:SF2 UPF0472 PROTEIN C16ORF72 HUWE1-ASSOCIATED PROTEIN MODIFYING STRESS RESPONSES 2 GORGO|Ensembl=ENSGGOG00000024480.2|UniProtKB=G3SH86 G3SH86 ZBTB39 PTHR24409:SF310 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN CONTAINING 39 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014547.3|UniProtKB=G3RF28 G3RF28 NDUFV3 PTHR17117:SF3 NADH-UBIQUINONE OXIDOREDUCTASE NADH:UBIQUINONE OXIDOREDUCTASE SUBUNIT V3 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005782.3|UniProtKB=G3QSM2 G3QSM2 ARSK PTHR46615:SF1 ARYLSULFATASE K ARYLSULFATASE K catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 GORGO|Ensembl=ENSGGOG00000000290.3|UniProtKB=G3QDG8 G3QDG8 CITED1 PTHR17045:SF6 MELANOCYTE SPECIFIC GENE RELATED CITED CBP_P300-INTERACTING TRANSACTIVATOR 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to hormone#GO:0009725;cellular process#GO:0009987;melanocyte differentiation#GO:0030318;developmental pigmentation#GO:0048066;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to stimulus#GO:0050896;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;pigmentation#GO:0043473;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 GORGO|Ensembl=ENSGGOG00000015604.3|UniProtKB=G3RHU3 G3RHU3 ARL6IP6 PTHR28640:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 GORGO|Ensembl=ENSGGOG00000001569.3|UniProtKB=G3QGT3 G3QGT3 YWHAQ PTHR18860:SF3 14-3-3 PROTEIN 14-3-3 PROTEIN THETA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 GORGO|Ensembl=ENSGGOG00000037929.1|UniProtKB=G3S117 G3S117 LOC101131235 PTHR19944:SF97 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 4 CHAIN-RELATED antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488;protein-containing complex binding#GO:0044877 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell adhesion#GO:0045785;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;regulation of immune response#GO:0050776;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cellular process#GO:0048522;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of lymphocyte activation#GO:0051249;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of T cell activation#GO:0050863;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of leukocyte activation#GO:0002696 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852 major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000022176.2|UniProtKB=G3SAG5 G3SAG5 BTK PTHR24418:SF92 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BTK catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;non-membrane spanning protein tyrosine kinase activity#GO:0004715 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Btk#P00400 GORGO|Ensembl=ENSGGOG00000038755.1|UniProtKB=A0A2I2Z7A2 A0A2I2Z7A2 GFY PTHR47641:SF14 PERIAXIN-LIKE GOLGI-ASSOCIATED OLFACTORY SIGNALING REGULATOR GORGO|Ensembl=ENSGGOG00000000611.3|UniProtKB=G3SFV1 G3SFV1 STAT1 PTHR11801:SF18 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA_BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to hormone#GO:0009725;response to stress#GO:0006950;interleukin-9-mediated signaling pathway#GO:0038113;cell surface receptor signaling pathway via STAT#GO:0097696;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;defense response to other organism#GO:0098542;response to lipid#GO:0033993;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;interleukin-7-mediated signaling pathway#GO:0038111;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;response to endogenous stimulus#GO:0009719;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;type I interferon-mediated signaling pathway#GO:0060337;response to peptide#GO:1901652;immune response#GO:0006955;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;response to peptide hormone#GO:0043434;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;innate immune response#GO:0045087;cellular response to molecule of bacterial origin#GO:0071219;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832;JAK/STAT signaling pathway#P00038>STAT#P01027;Oxidative stress response#P00046>Stat1#P01125;Oxidative stress response#P00046>Myc#P01124;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;Interferon-gamma signaling pathway#P00035>STAT1#P00961;Angiogenesis#P00005>STAT1#P00218;Ras Pathway#P04393>Stat 1/3#P04566;p53 pathway feedback loops 2#P04398>Myc#P04649;Interleukin signaling pathway#P00036>STAT#P00996 GORGO|Ensembl=ENSGGOG00000006259.3|UniProtKB=G3QTU6 G3QTU6 CCDC142 PTHR21436:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 142 COILED-COIL DOMAIN-CONTAINING PROTEIN 142 GORGO|Ensembl=ENSGGOG00000042594.1|UniProtKB=A0A2I2ZF39 A0A2I2ZF39 PTHR11710:SF27 40S RIBOSOMAL PROTEIN S19 40S RIBOSOMAL PROTEIN S19 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007208.3|UniProtKB=G3S870 G3S870 IGSF22 PTHR13817:SF153 TITIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 22 structural molecule activity#GO:0005198 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;supramolecular fiber organization#GO:0097435 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;contractile muscle fiber#GO:0043292;A band#GO:0031672;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016;intracellular organelle#GO:0043229;M band#GO:0031430 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000007309.3|UniProtKB=A0A2I2YZ87 A0A2I2YZ87 LOC101153764 PTHR15422:SF9 OS05G0565100 PROTEIN TRANSMEMBRANE REDUCTASE CYB561D1-RELATED GORGO|Ensembl=ENSGGOG00000005918.3|UniProtKB=A0A2I2Z0A8 A0A2I2Z0A8 ETV1 PTHR11849:SF196 ETS ETS TRANSLOCATION VARIANT 1 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000006126.3|UniProtKB=G3QTH4 G3QTH4 PTHR28610:SF1 DRAXIN DRAXIN cell projection morphogenesis#GO:0048858;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;negative regulation of signal transduction#GO:0009968;nervous system development#GO:0007399;head development#GO:0060322;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;neuron projection development#GO:0031175;negative regulation of cell communication#GO:0010648;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of Wnt signaling pathway#GO:0030111;cell development#GO:0048468;forebrain development#GO:0030900;cell morphogenesis#GO:0000902;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;central nervous system neuron differentiation#GO:0021953;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;plasma membrane bounded cell projection organization#GO:0120036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of Wnt signaling pathway#GO:0030178;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;brain development#GO:0007420;axon development#GO:0061564;axon guidance#GO:0007411;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000006620.3|UniProtKB=A0A2I2Z1K5 A0A2I2Z1K5 PEX13 PTHR19332:SF1 PEROXISOMAL MEMBRANE PROTEIN PEX13 PEROXISOMAL MEMBRANE PROTEIN PEX13 protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein transport#GO:0015031;peroxisomal transport#GO:0043574;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;peroxisome organization#GO:0007031;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;protein-containing complex#GO:0032991;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000038276.1|UniProtKB=A0A2I2ZSF2 A0A2I2ZSF2 NEUROG2 PTHR19290:SF171 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;forebrain development#GO:0030900;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000010003.3|UniProtKB=G3R3D7 G3R3D7 TSPAN6 PTHR19282:SF169 TETRASPANIN TETRASPANIN-6 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016062.3|UniProtKB=G3S5I6 G3S5I6 IPO4 PTHR10527:SF6 IMPORTIN BETA IMPORTIN-4 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000038888.1|UniProtKB=A0A2I2YTG1 A0A2I2YTG1 PTHR43920:SF7 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL PROTEIN 4 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821 membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000003500.3|UniProtKB=A0A2I2YTG3 A0A2I2YTG3 VGLL4 PTHR17604:SF1 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 transcription factor binding#GO:0008134;binding#GO:0005488;protein binding#GO:0005515 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000012704.3|UniProtKB=G3S3V9 G3S3V9 TOP2A PTHR10169:SF61 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2-ALPHA ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545 sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;reciprocal homologous recombination#GO:0140527;cell death#GO:0008219;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;homologous recombination#GO:0035825;reproductive process#GO:0022414;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;chromosome condensation#GO:0030261;cellular component disassembly#GO:0022411;execution phase of apoptosis#GO:0097194;cell cycle process#GO:0022402;apoptotic process#GO:0006915;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996 chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 GORGO|Ensembl=ENSGGOG00000040128.1|UniProtKB=G3RNK8 G3RNK8 H2AC19 PTHR23430:SF130 HISTONE H2A HISTONE H2A TYPE 2-C structural molecule activity#GO:0005198 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010942.3|UniProtKB=G3R5S8 G3R5S8 SPATA2L PTHR15326:SF7 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2-LIKE PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000042492.1|UniProtKB=A0A2I2Y3N2 A0A2I2Y3N2 PTHR39223:SF1 RIKEN CDNA 1700029H14 GENE 1700029H14RIK PROTEIN GORGO|Ensembl=ENSGGOG00000026972.2|UniProtKB=G3SG58 G3SG58 PTHR24377:SF924 IP01015P-RELATED ZINC FINGER PROTEIN 774 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Gene=OR1E2|UniProtKB=Q9TQX4 Q9TQX4 OR1E2 PTHR48001:SF130 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1E3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004744.3|UniProtKB=G3SJD9 G3SJD9 DUSP22 PTHR45948:SF3 DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED DUAL SPECIFICITY PROTEIN PHOSPHATASE 22 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 response to transforming growth factor beta#GO:0071559;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;positive regulation of signal transduction#GO:0009967;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;regulation of JNK cascade#GO:0046328;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000043523.1|UniProtKB=A0A2I2YF98 A0A2I2YF98 DPH3 PTHR21454:SF24 DPH3 HOMOLOG-RELATED DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3 iron ion binding#GO:0005506;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000040075.1|UniProtKB=G3RUR0 G3RUR0 LOC101126984 PTHR11417:SF67 SOMATOTROPIN,PROLACTIN CHORIONIC SOMATOMAMMOTROPIN HORMONE 1-RELATED molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;positive regulation of response to stimulus#GO:0048584;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;developmental process#GO:0032502;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of signaling#GO:0023056;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;animal organ development#GO:0048513;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000016838.3|UniProtKB=G3RKZ6 G3RKZ6 TNFRSF9 PTHR47139:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007;regulation of biological process#GO:0050789 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003074.3|UniProtKB=G3QKP8 G3QKP8 FLII PTHR11977:SF142 VILLIN PROTEIN FLIGHTLESS-1 HOMOLOG cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;actin binding#GO:0003779;actin filament binding#GO:0051015;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515 negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;negative regulation of protein-containing complex assembly#GO:0031333;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;negative regulation of organelle organization#GO:0010639;regulation of actin filament depolymerization#GO:0030834;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;actin polymerization or depolymerization#GO:0008154;biological regulation#GO:0065007;regulation of actin filament length#GO:0030832;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;striated muscle cell development#GO:0055002;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;regulation of anatomical structure size#GO:0090066;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin filament capping#GO:0051693;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of supramolecular fiber organization#GO:1902903;myofibril assembly#GO:0030239;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;cellular developmental process#GO:0048869;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;regulation of protein-containing complex disassembly#GO:0043244;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;actin cytoskeleton#GO:0015629;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000024528.2|UniProtKB=A0A2I2ZJ18 A0A2I2ZJ18 SHISA6 PTHR31774:SF0 PROTEIN SHISA-9-RELATED PROTEIN SHISA-6 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of synaptic plasticity#GO:0048167;regulation of biological quality#GO:0065008;regulation of neuronal synaptic plasticity#GO:0048168 neuron spine#GO:0044309;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;postsynaptic membrane#GO:0045211;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell leading edge#GO:0031252;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;dendrite#GO:0030425;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589 GORGO|Ensembl=ENSGGOG00000026508.2|UniProtKB=G3RSD3 G3RSD3 STAU2 PTHR46054:SF1 MATERNAL EFFECT PROTEIN STAUFEN DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;double-stranded RNA binding#GO:0003725 reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;microtubule-based movement#GO:0007018;RNA localization#GO:0006403;gamete generation#GO:0007276;cell differentiation#GO:0030154;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;sexual reproduction#GO:0019953;microtubule-based transport#GO:0099111;protein localization to cell junction#GO:1902414;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;macromolecule localization#GO:0033036;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;protein localization to synapse#GO:0035418;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907 intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;cell body#GO:0044297;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000042948.1|UniProtKB=A0A2I2ZPW2 A0A2I2ZPW2 PTHR10934:SF6 60S RIBOSOMAL PROTEIN L18 LARGE RIBOSOMAL SUBUNIT PROTEIN EL18 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011872.3|UniProtKB=G3S2W7 G3S2W7 MDK PTHR13850:SF2 PLEIOTROPHIN FAMILY MEMBER MIDKINE molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545 growth factor#PC00112;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000007337.3|UniProtKB=A0A2I2YVK1 A0A2I2YVK1 BCL11A PTHR45993:SF5 B-CELL LYMPHOMA/LEUKEMIA 11 BCL11 TRANSCRIPTION FACTOR A RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of neuron projection development#GO:0010975;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;regulation of developmental process#GO:0050793 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000006842.3|UniProtKB=G3QVD1 G3QVD1 THAP3 PTHR47120:SF1 THAP DOMAIN-CONTAINING PROTEIN 3 THAP DOMAIN-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000001426.3|UniProtKB=G3QGF3 G3QGF3 KLK9 PTHR24271:SF57 KALLIKREIN-RELATED KALLIKREIN-9 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;extracellular region#GO:0005576;intracellular organelle#GO:0043229 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000038094.1|UniProtKB=A0A2I2YT68 A0A2I2YT68 PTHR23105:SF206 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER 60S RIBOSOMAL PROTEIN L7A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000036272.1|UniProtKB=G3RR30 G3RR30 ZNF451 PTHR24408:SF61 ZINC FINGER PROTEIN E3 SUMO-PROTEIN LIGASE ZNF451 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;SUMO ligase activity#GO:0061665;transcription regulator activity#GO:0140110;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;transcription corepressor activity#GO:0003714;sequence-specific DNA binding#GO:0043565;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein sumoylation#GO:0016925;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;metabolic process#GO:0008152;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-translational protein modification#GO:0043687;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription initiation#GO:2000142;protein modification process#GO:0036211;primary metabolic process#GO:0044238 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000028565.2|UniProtKB=A1YF22 A1YF22 ZHX1 PTHR15467:SF4 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000014225.3|UniProtKB=G3RE98 G3RE98 ALB PTHR11385:SF15 SERUM ALBUMIN-RELATED ALBUMIN small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363 response to nutrient levels#GO:0031667;response to stimulus#GO:0050896 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000004669.3|UniProtKB=G3QPS5 G3QPS5 HSPA14 PTHR19375:SF438 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 14 ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ribonucleoside triphosphate phosphatase activity#GO:0017111;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Hsp70 family chaperone#PC00027;chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000027901.2|UniProtKB=G3SJE5 G3SJE5 LTV1 PTHR21531:SF0 LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED PROTEIN LTV1 HOMOLOG establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;transport#GO:0006810;ribosomal small subunit biogenesis#GO:0042274;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;ribosome localization#GO:0033750;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014789.3|UniProtKB=G3RFQ5 G3RFQ5 COQ4 PTHR12922:SF10 UBIQUINONE BIOSYNTHESIS PROTEIN UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ketone metabolic process#GO:0042180 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000009029.3|UniProtKB=G3R0X9 G3R0X9 CIMIP2B PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 CILIARY MICROTUBULE INNER PROTEIN 2B GORGO|Ensembl=ENSGGOG00000038081.1|UniProtKB=A0A2I2Y870 A0A2I2Y870 NDUFAF4 PTHR13338:SF6 UPF0240 PROTEIN NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 4 mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000007639.3|UniProtKB=G3QXD2 G3QXD2 TSPAN11 PTHR19282:SF198 TETRASPANIN TETRASPANIN-11 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000023065.3|UniProtKB=G3RN86 G3RN86 CENATAC PTHR31198:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 84 CENTROSOMAL AT-AC SPLICING FACTOR GORGO|Ensembl=ENSGGOG00000001366.3|UniProtKB=A0A2I2ZQ20 A0A2I2ZQ20 ATG4D PTHR22624:SF36 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4D hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;protein-phosphatidylethanolamide deconjugating activity#GO:0019786 autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;organelle assembly#GO:0070925;proteolysis#GO:0006508;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000040613.1|UniProtKB=A0A2I2Z7Q2 A0A2I2Z7Q2 PTHR13976:SF86 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RRM DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000007191.3|UniProtKB=G3QW86 G3QW86 LOC101137280 PTHR14787:SF3 C10ORF188 FAMILY MEMBER ATPASE PAAT ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000011769.3|UniProtKB=A0A2I2ZKT3 A0A2I2ZKT3 NPSR1 PTHR24244:SF2 NEUROPEPTIDE S RECEPTOR NEUROPEPTIDE S RECEPTOR neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic ion transmembrane transport#GO:0034765;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of transmembrane transport#GO:0034762;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000006725.3|UniProtKB=G3QV18 G3QV18 YAE1 PTHR18829:SF0 PROTEIN YAE1 HOMOLOG PROTEIN YAE1 HOMOLOG GORGO|Ensembl=ENSGGOG00000027955.2|UniProtKB=G3S9B3 G3S9B3 APLNR PTHR24228:SF31 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR APELIN RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;regulation of biological process#GO:0050789;vasculature development#GO:0001944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000036746.1|UniProtKB=A0A2I2YSY7 A0A2I2YSY7 PTHR14572:SF0 PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR GORGO|Ensembl=ENSGGOG00000000963.3|UniProtKB=G3QF83 G3QF83 TVP23A PTHR13019:SF18 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG A macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;localization#GO:0051179;protein secretion#GO:0009306;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 GORGO|Ensembl=ENSGGOG00000026083.2|UniProtKB=G3RQ26 G3RQ26 TRIM69 PTHR24103:SF286 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM69 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000010525.3|UniProtKB=G3R4Q5 G3R4Q5 B4GAT1 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000016887.3|UniProtKB=A0A2I2Z7D0 A0A2I2Z7D0 SLC4A2 PTHR11453:SF14 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 2 chloride transmembrane transporter activity#GO:0015108;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000037311.1|UniProtKB=A0A2I2YZ29 A0A2I2YZ29 TMEM41A PTHR43220:SF21 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41A GORGO|Ensembl=ENSGGOG00000007623.3|UniProtKB=A0A2I2Z1W9 A0A2I2Z1W9 EGFR PTHR24416:SF91 TYROSINE-PROTEIN KINASE RECEPTOR EPIDERMAL GROWTH FACTOR RECEPTOR molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;hormone binding#GO:0042562;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740 neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;epidermal growth factor receptor signaling pathway#GO:0007173;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;multicellular organism development#GO:0007275;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284 plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>EGFR#P00466;EGF receptor signaling pathway#P00018>EGFR#P00542;Gonadotropin-releasing hormone receptor pathway#P06664>EGFR#P06843 GORGO|Ensembl=ENSGGOG00000010287.3|UniProtKB=G3R453 G3R453 TMEM175 PTHR31462:SF5 ENDOSOMAL/LYSOSOMAL POTASSIUM CHANNEL TMEM175 ENDOSOMAL_LYSOSOMAL PROTON CHANNEL TMEM175 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000011276.3|UniProtKB=G3R6N4 G3R6N4 PTHR11592:SF134 GLUTATHIONE PEROXIDASE PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE GPX4 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;response to stress#GO:0006950;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular response to stress#GO:0033554;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887 oxidoreductase#PC00176;peroxidase#PC00180 GORGO|Ensembl=ENSGGOG00000001794.3|UniProtKB=G3QHE4 G3QHE4 CEP350 PTHR13958:SF4 CENTROSOME-ASSOCIATED PROTEIN 350 CENTROSOME-ASSOCIATED PROTEIN 350 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000001179.3|UniProtKB=G3QFT3 G3QFT3 TTC1 PTHR46014:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 GORGO|Ensembl=ENSGGOG00000001959.3|UniProtKB=A0A2I2YD09 A0A2I2YD09 PLCL1 PTHR10336:SF102 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN INACTIVE PHOSPHOLIPASE C-LIKE PROTEIN 1 lipase activity#GO:0016298;hydrolase activity#GO:0016787;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;regulation of signaling#GO:0023051 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530 GORGO|Ensembl=ENSGGOG00000011578.3|UniProtKB=G3R7G0 G3R7G0 PTHR46467:SF1 TETHER CONTAINING UBX DOMAIN FOR GLUT4 TETHER CONTAINING UBX DOMAIN FOR GLUT4 glucose homeostasis#GO:0042593;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;homeostatic process#GO:0042592;carbohydrate homeostasis#GO:0033500 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000012915.3|UniProtKB=G3RAW6 G3RAW6 FATE1 PTHR21128:SF0 FETAL AND ADULT TESTIS-EXPRESSED TRANSCRIPT PROTEIN FETAL AND ADULT TESTIS-EXPRESSED TRANSCRIPT PROTEIN enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;negative regulation of programmed cell death#GO:0043069;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;negative regulation of cellular process#GO:0048523;chemical homeostasis#GO:0048878;regulation of apoptotic process#GO:0042981;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;regulation of cellular process#GO:0050794;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane contact site#GO:0044232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004262.3|UniProtKB=G3QNQ9 G3QNQ9 SEC14L3 PTHR23324:SF62 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 3 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000000023.3|UniProtKB=G3QCS7 G3QCS7 LOC101152234 PTHR22588:SF5 VWFA DOMAIN-CONTAINING PROTEIN COLLAGEN ALPHA-6(VI) CHAIN external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000004576.3|UniProtKB=G3QPI9 G3QPI9 CLEC3B PTHR22799:SF3 TETRANECTIN-RELATED TETRANECTIN biomineral tissue development#GO:0031214;developmental process#GO:0032502;bone mineralization#GO:0030282;animal gross anatomical part developmental process#GO:0160108;animal organ development#GO:0048513;anatomical structure development#GO:0048856;tissue development#GO:0009888;ossification#GO:0001503;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000014211.3|UniProtKB=G3RE80 G3RE80 PROKR2 PTHR24241:SF125 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PROKINETICIN RECEPTOR 2 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;circadian rhythm#GO:0007623;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;rhythmic process#GO:0048511;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007963.3|UniProtKB=G3QY60 G3QY60 DNASE2B PTHR10858:SF2 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE-2-BETA endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;catabolic process#GO:0009056;apoptotic process#GO:0006915;cell death#GO:0008219;execution phase of apoptosis#GO:0097194;programmed cell death#GO:0012501;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 endodeoxyribonuclease#PC00093 GORGO|Ensembl=ENSGGOG00000005850.3|UniProtKB=G3QSS7 G3QSS7 TNFSF18 PTHR15267:SF1 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 18 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 18 protein binding#GO:0005515;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;signaling#GO:0023052;response to stimulus#GO:0050896;mononuclear cell proliferation#GO:0032943;T cell proliferation#GO:0042098;immune system process#GO:0002376;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;cellular process#GO:0009987;lymphocyte activation involved in immune response#GO:0002285;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;T cell activation involved in immune response#GO:0002286;regulation of response to external stimulus#GO:0032101;lymphocyte activation#GO:0046649;response to chemical#GO:0042221;response to cytokine#GO:0034097;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;leukocyte activation involved in immune response#GO:0002366;positive regulation of response to external stimulus#GO:0032103;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte migration#GO:0002685;cell activation#GO:0001775;regulation of granulocyte chemotaxis#GO:0071622;cell population proliferation#GO:0008283;cytokine-mediated signaling pathway#GO:0019221;tumor necrosis factor-mediated signaling pathway#GO:0033209;positive regulation of chemotaxis#GO:0050921;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;response to tumor necrosis factor#GO:0034612;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;lymphocyte proliferation#GO:0046651;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;leukocyte proliferation#GO:0070661;positive regulation of locomotion#GO:0040017 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000040879.1|UniProtKB=G3RQ76 G3RQ76 LOC101142869 PTHR23430:SF378 HISTONE H2A HISTONE H2A TYPE 1-J structural molecule activity#GO:0005198 regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000013622.3|UniProtKB=G3S8C7 G3S8C7 PRSS36 PTHR24253:SF100 TRANSMEMBRANE PROTEASE SERINE POLYSERASE-2 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000008670.3|UniProtKB=G3R001 G3R001 TSKU PTHR24373:SF352 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TSUKUSHI signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000021976.2|UniProtKB=A0A2I2Y964 A0A2I2Y964 NANS PTHR42966:SF1 N-ACETYLNEURAMINATE SYNTHASE N-ACETYLNEURAMINATE-9-PHOSPHATE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolite interconversion enzyme#PC00262;acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000015227.3|UniProtKB=G3RGU9 G3RGU9 ANKRD2 PTHR24126:SF3 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000012559.3|UniProtKB=G3R9Z9 G3R9Z9 SNAI3 PTHR24388:SF40 ZINC FINGER PROTEIN ZINC FINGER PROTEIN SNAI3 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000043927.1|UniProtKB=A0A2I2Z3G8 A0A2I2Z3G8 UST PTHR12129:SF15 HEPARAN SULFATE 2-O-SULFOTRANSFERASE URONYL 2-SULFOTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000023839.2|UniProtKB=G3SFM9 G3SFM9 PTHR11711:SF347 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 17 C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000008955.3|UniProtKB=G3R0R0 G3R0R0 CHSY1 PTHR12369:SF42 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 1 hexosyltransferase activity#GO:0016758;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000009693.3|UniProtKB=G3R2L5 G3R2L5 PIGS PTHR21072:SF13 GPI TRANSAMIDASE COMPONENT PIG-S GPI-ANCHOR TRANSAMIDASE COMPONENT PIGS protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 endopeptidase complex#GO:1905369;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;peptidase complex#GO:1905368;cytoplasm#GO:0005737;caspase complex#GO:0008303;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004202.3|UniProtKB=A0A2I2YUF0 A0A2I2YUF0 ELOF1 PTHR20934:SF0 TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000027775.2|UniProtKB=G3RTA5 G3RTA5 GCNT4 PTHR19297:SF7 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000014545.3|UniProtKB=G3RF34 G3RF34 NOP58 PTHR10894:SF1 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 58 binding#GO:0005488;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005712.3|UniProtKB=G3SFI0 G3SFI0 CDH5 PTHR24027:SF89 CADHERIN-23 CADHERIN-5 cell adhesion molecule binding#GO:0050839;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;beta-catenin binding#GO:0008013;protein phosphatase binding#GO:0019903;protein binding#GO:0005515 cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cell migration#GO:0016477;cellular component assembly#GO:0022607;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870 anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;apical junction complex#GO:0043296;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;tight junction#GO:0070160;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;bicellular tight junction#GO:0005923 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000011888.3|UniProtKB=G3R895 G3R895 AQP10 PTHR43829:SF13 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-10 channel activity#GO:0015267;carbohydrate transmembrane transporter activity#GO:0015144;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 transport#GO:0006810;carbohydrate transport#GO:0008643;fluid transport#GO:0042044;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;water transport#GO:0006833;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000000511.3|UniProtKB=A0A2I2YMC3 A0A2I2YMC3 ADRA1A PTHR24248:SF16 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1A ADRENERGIC RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;regulation of biological quality#GO:0065008;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 GORGO|Ensembl=ENSGGOG00000003921.3|UniProtKB=G3QMV3 G3QMV3 SEC23IP PTHR23509:SF4 PA-PL1 PHOSPHOLIPASE FAMILY SEC23-INTERACTING PROTEIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;cellular process#GO:0009987;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869 coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 metabolite interconversion enzyme#PC00262;phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000011166.3|UniProtKB=G3R6D6 G3R6D6 SMCO4 PTHR34644:SF2 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000006049.3|UniProtKB=G3QTA7 G3QTA7 MFAP4 PTHR19143:SF225 FIBRINOGEN/TENASCIN/ANGIOPOEITIN MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 4 cellular component assembly#GO:0022607;extracellular matrix assembly#GO:0085029;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;supramolecular fiber organization#GO:0097435;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000014718.3|UniProtKB=A0A2I2ZQA1 A0A2I2ZQA1 OPTN PTHR31553:SF2 NF-KAPPA-B ESSENTIAL MODULATOR OPTINEURIN K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;modification-dependent protein binding#GO:0140030;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein localization to Golgi apparatus#GO:0034067;regulation of response to stimulus#GO:0048583;endomembrane system organization#GO:0010256;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;macromolecule localization#GO:0033036;organelle organization#GO:0006996;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;localization#GO:0051179;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cell communication#GO:0010646;cellular component organization#GO:0016043;Golgi organization#GO:0007030;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 Huntington disease#P00029>FIP-2#P00772 GORGO|Ensembl=ENSGGOG00000003386.3|UniProtKB=G3QLI6 G3QLI6 CACNA1G PTHR10037:SF137 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1G channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated sodium channel activity#GO:0005248;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 calcium ion transport#GO:0006816;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of membrane potential#GO:0042391;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of secretion by cell#GO:1903530;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;positive regulation of secretion#GO:0051047;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of vesicle-mediated transport#GO:0060627;action potential#GO:0001508;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of exocytosis#GO:0017157;localization#GO:0051179;regulation of secretion#GO:0051046;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;regulation of cellular process#GO:0050794;calcium ion import#GO:0070509 cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;neuron projection#GO:0043005;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;GABA-B receptor II signaling#P05731>Ca channel#P05753;Nicotine pharmacodynamics pathway#P06587>CACNA#P06600 GORGO|Ensembl=ENSGGOG00000014682.3|UniProtKB=G3RFF3 G3RFF3 PTHR21346:SF4 FUN14 DOMAIN CONTAINING FUN14 DOMAIN-CONTAINING PROTEIN 2 catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular process#GO:0009987;autophagy#GO:0006914 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000009901.3|UniProtKB=A0A2I2Y530 A0A2I2Y530 TFEC PTHR45776:SF1 MIP04163P TRANSCRIPTION FACTOR EC transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000002058.3|UniProtKB=G3RPU6 G3RPU6 LCT PTHR10353:SF38 GLYCOSYL HYDROLASE LACTASE_PHLORIZIN HYDROLASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;beta-glucosidase activity#GO:0008422;glucosidase activity#GO:0015926;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;cellular process#GO:0009987;primary metabolic process#GO:0044238 external side of plasma membrane#GO:0009897;apical part of cell#GO:0045177;side of membrane#GO:0098552;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;glycosidase#PC00110;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000015920.4|UniProtKB=G3RIM3 G3RIM3 GPR158 PTHR32546:SF11 G-PROTEIN COUPLED RECEPTOR 158-RELATED METABOTROPIC GLYCINE RECEPTOR G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013261.3|UniProtKB=G3RBT3 G3RBT3 PTHR10799:SF923 SNF2/RAD54 HELICASE FAMILY PROLIFERATION-ASSOCIATED SNF2-LIKE PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 heterochromatin organization#GO:0070828;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000006923.3|UniProtKB=A0A2I2YZT2 A0A2I2YZT2 SP110 PTHR46386:SF7 NUCLEAR BODY PROTEIN SP140 SP110 NUCLEAR BODY PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000008589.3|UniProtKB=A0A2I2YLA4 A0A2I2YLA4 NKX3-2 PTHR24340:SF34 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000007723.3|UniProtKB=G3QXL4 G3QXL4 SV2C PTHR23511:SF6 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2C biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of cell communication#GO:0010646;regulation of synaptic vesicle exocytosis#GO:2000300;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588 vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000036567.1|UniProtKB=A0A2I2YDR4 A0A2I2YDR4 FILIP1L PTHR23166:SF4 FILAMIN/GPBP-INTERACTING PROTEIN FILAMIN A-INTERACTING PROTEIN 1-LIKE intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365;macromolecule localization#GO:0033036;protein localization to cytoskeleton#GO:0044380 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000003228.3|UniProtKB=A0A2I2YTQ4 A0A2I2YTQ4 TTC12 PTHR46540:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 12 TETRATRICOPEPTIDE REPEAT PROTEIN 12 germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;sperm motility#GO:0097722;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000014021.3|UniProtKB=G3RDS9 G3RDS9 KDM2B PTHR23123:SF10 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 2B protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone demethylase activity#GO:0032452 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000005868.4|UniProtKB=G3QSV0 G3QSV0 CPA6 PTHR11705:SF18 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A6 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000013580.3|UniProtKB=A0A2I2YEZ3 A0A2I2YEZ3 SLC26A8 PTHR11814:SF11 SULFATE TRANSPORTER TESTIS ANION TRANSPORTER 1 active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;chloride transmembrane transporter activity#GO:0015108;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014999.3|UniProtKB=A0A2I2ZR30 A0A2I2ZR30 CIZ1 PTHR15491:SF9 FAMILY NOT NAMED CIP1-INTERACTING ZINC FINGER PROTEIN regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA replication#GO:0045740;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of DNA-templated DNA replication initiation#GO:0030174;regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893;positive regulation of DNA metabolic process#GO:0051054;regulation of biological process#GO:0050789;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000010413.3|UniProtKB=A0A2I2Y7X8 A0A2I2Y7X8 MPL PTHR23037:SF31 CYTOKINE RECEPTOR THROMBOPOIETIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 anatomical structure development#GO:0048856;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;response to peptide#GO:1901652;G protein-coupled receptor signaling pathway#GO:0007186;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;myeloid cell differentiation#GO:0030099;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;cellular response to chemokine#GO:1990869;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;anatomical structure formation involved in morphogenesis#GO:0048646;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;hemopoiesis#GO:0030097;response to chemokine#GO:1990868;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002409.3|UniProtKB=G3QIZ7 G3QIZ7 SNX2 PTHR10555:SF31 SORTING NEXIN SORTING NEXIN-2 ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;retromer complex#GO:0030904;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016130.3|UniProtKB=G3RJ62 G3RJ62 KASH5 PTHR47300:SF1 PROTEIN KASH5 PROTEIN KASH5 protein-containing complex binding#GO:0044877;binding#GO:0005488 reproductive process#GO:0022414;actin cytoskeleton organization#GO:0030036;cell cycle#GO:0007049;telomere localization#GO:0034397;supramolecular fiber organization#GO:0097435;localization#GO:0051179;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;meiosis I cell cycle process#GO:0061982;organelle localization#GO:0051640;actin filament organization#GO:0007015;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;spindle organization#GO:0007051;meiotic nuclear division#GO:0140013;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;spindle localization#GO:0051653;nuclear division#GO:0000280;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;homologous chromosome pairing at meiosis#GO:0007129;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321 organelle lumen#GO:0043233;spindle pole#GO:0000922;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle lumen#GO:0070013;outer membrane#GO:0019867;intracellular organelle#GO:0043229;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;synaptonemal structure#GO:0099086;chromosome, telomeric region#GO:0000781;nuclear envelope#GO:0005635;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;nuclear protein-containing complex#GO:0140513;bounding membrane of organelle#GO:0098588;nuclear membrane#GO:0031965;chromosome#GO:0005694;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;nuclear chromosome#GO:0000228;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000026824.2|UniProtKB=G3RLY1 G3RLY1 NDUFAF8 PTHR34561:SF1 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000011005.3|UniProtKB=G3R5Y9 G3R5Y9 MRPS25 PTHR13274:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN MS25 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016340.3|UniProtKB=G3RJP4 G3RJP4 CCR7 PTHR10489:SF635 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 7 protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine receptor activity#GO:0004896 locomotion#GO:0040011;signaling#GO:0023052;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000015522.3|UniProtKB=G3RHM0 G3RHM0 HTR5A PTHR24247:SF108 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 5A G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;heterocyclic compound binding#GO:1901363;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;serotonin binding#GO:0051378;molecular transducer activity#GO:0060089 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 GORGO|Ensembl=ENSGGOG00000011848.3|UniProtKB=G3R856 G3R856 POLR3GL PTHR15367:SF4 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7-LIKE transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000024541.2|UniProtKB=G3RZF8 G3RZF8 MCEE PTHR43048:SF3 METHYLMALONYL-COA EPIMERASE METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL isomerase activity#GO:0016853;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854 purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 isomerase#PC00135;epimerase/racemase#PC00096 Methylmalonyl pathway#P02755>Methylmalonyl-CoA epimerase#P03032 GORGO|Ensembl=ENSGGOG00000000610.3|UniProtKB=G3QEB0 G3QEB0 TMPRSS15 PTHR24253:SF71 TRANSMEMBRANE PROTEASE SERINE ENTEROPEPTIDASE serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000013662.3|UniProtKB=G3RCU6 G3RCU6 SMAD4 PTHR13703:SF63 SMAD SMAD FAMILY MEMBER 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;BMP signaling pathway#GO:0030509;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to transforming growth factor beta#GO:0071559;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Wnt signaling pathway#P00057>Smad4#P01455;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>Co-Smads#P01276 GORGO|Ensembl=ENSGGOG00000014763.3|UniProtKB=A0A2I2ZK29 A0A2I2ZK29 PAK3 PTHR45832:SF11 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE GORGO|Ensembl=ENSGGOG00000002589.3|UniProtKB=G3QJF6 G3QJF6 HEY2 PTHR10985:SF88 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;pattern specification process#GO:0007389;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 GORGO|Ensembl=ENSGGOG00000004528.3|UniProtKB=A0A2I2YLV3 A0A2I2YLV3 FMNL1 PTHR45857:SF2 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 1 actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009636.3|UniProtKB=G3R2F6 G3R2F6 CRH PTHR15035:SF9 CORTICOLIBERIN/UROCORTIN CORTICOTROPIN-RELEASING HORMONE G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515 regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;positive regulation of signaling#GO:0023056;positive regulation of hormone secretion#GO:0046887;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;neuropeptide signaling pathway#GO:0007218;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of system process#GO:0044057;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;cellular process#GO:0009987 somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell body#GO:0044297 intercellular signal molecule#PC00207;peptide hormone#PC00179 Cortocotropin releasing factor receptor signaling pathway#P04380>CRF#P04454;Cortocotropin releasing factor receptor signaling pathway#P04380>ProCRF (Pro Corticotropin-Releasing Factor)#P04456 GORGO|Ensembl=ENSGGOG00000002351.3|UniProtKB=G3QIU6 G3QIU6 GIMAP4 PTHR10903:SF182 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000001332.3|UniProtKB=G3QG64 G3QG64 SP4 PTHR23235:SF17 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016386.3|UniProtKB=G3RJT4 G3RJT4 TADA2B PTHR12374:SF63 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-BETA binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;transcription coactivator activity#GO:0003713 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000024392.2|UniProtKB=G3SDG4 G3SDG4 PAICS PTHR43599:SF11 MULTIFUNCTIONAL PROTEIN ADE2 BIFUNCTIONAL PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE_PHOSPHORIBOSYLAMINOIMIDAZOLE SUCCINOCARBOXAMIDE SYNTHETASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013769.3|UniProtKB=G3RD35 G3RD35 AHSP PTHR15914:SF0 ALPHA-HEMOGLOBIN-STABILIZING PROTEIN ALPHA-HEMOGLOBIN-STABILIZING PROTEIN immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;protein metabolic process#GO:0019538;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;protein folding#GO:0006457;cell development#GO:0048468;metabolic process#GO:0008152;developmental process#GO:0032502;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;protein stabilization#GO:0050821;multicellular organismal-level homeostasis#GO:0048871;regulation of protein stability#GO:0031647;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;hemopoiesis#GO:0030097 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000013320.4|UniProtKB=G3RBZ1 G3RBZ1 UBAP2 PTHR16308:SF19 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER UBIQUITIN-ASSOCIATED PROTEIN 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000007166.3|UniProtKB=G3QW67 G3QW67 SLC17A1 PTHR11662:SF26 SOLUTE CARRIER FAMILY 17 SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 nitrogen compound transport#GO:0071705;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;phosphate ion transport#GO:0006817 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 GORGO|Ensembl=ENSGGOG00000003753.3|UniProtKB=G3QME7 G3QME7 SIAE PTHR22901:SF0 SIALATE O-ACETYLESTERASE SIALATE O-ACETYLESTERASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975 hydrolase#PC00121;esterase#PC00097 GORGO|Ensembl=ENSGGOG00000034857.2|UniProtKB=G3SKW3 G3SKW3 LOC101139066 PTHR16423:SF9 TREM-LIKE TRANSCRIPT PROTEIN TREM-LIKE TRANSCRIPT 4 PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of immune system process#GO:0002684;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of innate immune response#GO:0045088;positive regulation of response to external stimulus#GO:0032103;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 GORGO|Ensembl=ENSGGOG00000013289.3|UniProtKB=G3RBV0 G3RBV0 TRIM3 PTHR24104:SF21 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 3 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>HAC1#P00131 GORGO|Ensembl=ENSGGOG00000038492.1|UniProtKB=A0A2I2YNC6 A0A2I2YNC6 PTHR13085:SF4 MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 2 localization#GO:0051179;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein targeting#GO:0006605;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058 membrane#GO:0016020;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 protease#PC00190 GORGO|Ensembl=ENSGGOG00000027529.2|UniProtKB=G3RNC7 G3RNC7 LOC101146634 PTHR23226:SF398 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 72 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013762.3|UniProtKB=G3RD30 G3RD30 LOC101133928 PTHR11232:SF45 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER GENE 7694-RELATED receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;binding#GO:0005488;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 regulation of nervous system development#GO:0051960;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell development#GO:0060284;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of neurogenesis#GO:0050767 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Notch signaling pathway#P00045>Numb#P01118 GORGO|Ensembl=ENSGGOG00000006409.3|UniProtKB=A0A2I2YDR5 A0A2I2YDR5 YOD1 PTHR13312:SF0 HIV-INDUCED PROTEIN-7-LIKE PROTEASE UBIQUITIN THIOESTERASE OTU1 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to topologically incorrect protein#GO:0035967;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;response to unfolded protein#GO:0006986;cellular process#GO:0009987;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000000401.3|UniProtKB=G3QDR9 G3QDR9 DCHS1 PTHR24025:SF22 DESMOGLEIN FAMILY MEMBER PROTOCADHERIN-16 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000013534.3|UniProtKB=A0A2I2YRE2 A0A2I2YRE2 PTHR11761:SF26 50S/60S RIBOSOMAL PROTEIN L14/L23 60S RIBOSOMAL PROTEIN L23 nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000002591.3|UniProtKB=G3SDX9 G3SDX9 ZMPSTE24 PTHR10120:SF24 CAAX PRENYL PROTEASE 1 CAAX PRENYL PROTEASE 1 HOMOLOG catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000013316.3|UniProtKB=G3RBX2 G3RBX2 GNAT2 PTHR10218:SF68 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-2 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;cell communication#GO:0007154;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;cilium#GO:0005929;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;photoreceptor inner segment#GO:0001917;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117;G-protein#PC00020 Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;PI3 kinase pathway#P00048>Galpha#P01199 GORGO|Ensembl=ENSGGOG00000006140.3|UniProtKB=G3QTJ3 G3QTJ3 AOX1 PTHR11908:SF86 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000043432.1|UniProtKB=G3SJ64 G3SJ64 PTHR23268:SF14 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 12-3-RELATED signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000012320.3|UniProtKB=G3R9G4 G3R9G4 DUOX1 PTHR11972:SF75 NADPH OXIDASE DUAL OXIDASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;catalytic activity#GO:0003824 reactive oxygen species metabolic process#GO:0072593;response to stress#GO:0006950;metabolic process#GO:0008152;cellular process#GO:0009987;superoxide metabolic process#GO:0006801;response to stimulus#GO:0050896;defense response#GO:0006952 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;catalytic complex#GO:1902494 oxidase#PC00175;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000023360.2|UniProtKB=G3SHF9 G3SHF9 GCM2 PTHR12414:SF7 GLIAL CELLS MISSING RELATED/GLIDE CHORION-SPECIFIC TRANSCRIPTION FACTOR GCMB sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;gliogenesis#GO:0042063;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000008720.3|UniProtKB=G3R047 G3R047 DDT PTHR11954:SF21 D-DOPACHROME DECARBOXYLASE D-DOPACHROME DECARBOXYLASE catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lyase#PC00144;decarboxylase#PC00089 GORGO|Ensembl=ENSGGOG00000008713.3|UniProtKB=G3RTX6 G3RTX6 NUMBL PTHR47368:SF4 NUMB NUMB-LIKE PROTEIN positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of nervous system development#GO:0051960;regulation of neurogenesis#GO:0050767;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of nervous system development#GO:0051962;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000006235.3|UniProtKB=G3QTR8 G3QTR8 SQOR PTHR10632:SF2 SULFIDE:QUINONE OXIDOREDUCTASE SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;anion binding#GO:0043168 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000042856.1|UniProtKB=A0A2I2YCS7 A0A2I2YCS7 PTHR24286:SF218 CYTOCHROME P450 26 CYTOCHROME P450 FAMILY 51 SUBFAMILY A MEMBER 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;secondary alcohol biosynthetic process#GO:1902653;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 oxygenase#PC00177 GORGO|Gene=MCPH1|UniProtKB=P61591 P61591 MCPH1 PTHR14625:SF3 MICROCEPHALIN MICROCEPHALIN cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000039584.1|UniProtKB=A0A2I2Z7D8 A0A2I2Z7D8 LDHAL6A PTHR43128:SF9 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A-LIKE 6A oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 energy derivation by oxidation of organic compounds#GO:0015980;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000003165.3|UniProtKB=G3QKY1 G3QKY1 ADARB2 PTHR10910:SF17 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN INACTIVE DOUBLE-STRANDED RNA-SPECIFIC EDITASE B2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;tRNA-specific adenosine deaminase activity#GO:0008251;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;hydrolase activity#GO:0016787;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;base conversion or substitution editing#GO:0016553;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;adenosine to inosine editing#GO:0006382;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013097.3|UniProtKB=A0A2I2YBM1 A0A2I2YBM1 NCAM1 PTHR10075:SF120 BASIGIN RELATED NEURAL CELL ADHESION MOLECULE 1 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000038843.1|UniProtKB=A0A2I2ZXA6 A0A2I2ZXA6 BTN2A2 PTHR24100:SF156 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 2 MEMBER A2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000014283.3|UniProtKB=G3REE8 G3REE8 TBC1D10B PTHR22957:SF207 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 10B enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000001409.3|UniProtKB=G3QGD7 G3QGD7 LOC101146696 PTHR24291:SF3 CYTOCHROME P450 FAMILY 4 25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 vitamin D metabolic process#GO:0042359;steroid biosynthetic process#GO:0006694;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;response to lipid#GO:0033993;lipid biosynthetic process#GO:0008610;response to chemical#GO:0042221;cellular process#GO:0009987;lipid catabolic process#GO:0016042;alcohol biosynthetic process#GO:0046165;response to nutrient levels#GO:0031667;steroid catabolic process#GO:0006706;response to oxygen-containing compound#GO:1901700;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603;Vitamin D metabolism and pathway#P04396>25-Hydroxylase#P04601 GORGO|Ensembl=ENSGGOG00000022665.2|UniProtKB=A0A2I2ZHL0 A0A2I2ZHL0 GLUD2 PTHR11606:SF15 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE 2, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 GORGO|Ensembl=ENSGGOG00000005814.3|UniProtKB=G3QSP8 G3QSP8 PDCD7 PTHR48190:SF2 PROGRAMMED CELL DEATH PROTEIN 7 PROGRAMMED CELL DEATH PROTEIN 7 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 GORGO|Ensembl=ENSGGOG00000004373.3|UniProtKB=G3QP06 G3QP06 CCDC124 PTHR21680:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002518.3|UniProtKB=A0A2I2Y664 A0A2I2Y664 OR52E4 PTHR26450:SF13 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010627.3|UniProtKB=G3R504 G3R504 EFCAB10 PTHR21847:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement#GO:0003341 intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;radial spoke#GO:0001534;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000012504.3|UniProtKB=G3R9V1 G3R9V1 PTHR24228:SF55 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G PROTEIN-COUPLED RECEPTOR 75-RELATED molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000023292.3|UniProtKB=G3S4N2 G3S4N2 CLIC2 PTHR45476:SF3 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;localization#GO:0051179;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000002735.3|UniProtKB=G3QJU0 G3QJU0 HLX PTHR46808:SF1 H2.0-LIKE HOMEOBOX PROTEIN H2.0-LIKE HOMEOBOX PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000012247.3|UniProtKB=G3R964 G3R964 IFI30 PTHR13234:SF81 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;lysosome#GO:0005764 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000027074.2|UniProtKB=G3S1M0 G3S1M0 RAB26 PTHR47978:SF65 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-26 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of secretion#GO:0051046;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530 Golgi apparatus#GO:0005794;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000041574.1|UniProtKB=A0A2I2ZES0 A0A2I2ZES0 OR13C3 PTHR26453:SF34 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010384.3|UniProtKB=A0A2I2YNR7 A0A2I2YNR7 PKD2L2 PTHR10877:SF47 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2-LIKE PROTEIN 2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628;detection of mechanical stimulus#GO:0050982;detection of stimulus#GO:0051606 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000007112.3|UniProtKB=G3QW17 G3QW17 KIF20A PTHR24115:SF352 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF20A microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;microtubule#GO:0005874;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000012219.3|UniProtKB=G3R942 G3R942 CLEC4E PTHR22802:SF402 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER E signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;binding#GO:0005488 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000016905.3|UniProtKB=G3RL68 G3RL68 LOC101131274 PTHR14199:SF35 NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 6-LIKE PROTEIN NBPF FAMILY MEMBER NBPF1-RELATED GORGO|Ensembl=ENSGGOG00000006331.3|UniProtKB=G3QU04 G3QU04 FCRL4 PTHR11481:SF64 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000015879.3|UniProtKB=G3RII1 G3RII1 PTHR34438:SF1 SI:DKEY-97L20.6 CHROMOSOME 2 OPEN READING FRAME 81 GORGO|Ensembl=ENSGGOG00000002014.3|UniProtKB=G3RZ56 G3RZ56 PRAMEF17 PTHR14224:SF2 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 17 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul2-RING ubiquitin ligase complex#GO:0031462;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000034951.2|UniProtKB=G3SKK2 G3SKK2 UXS1 PTHR43078:SF54 UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED UDP-GLUCURONIC ACID DECARBOXYLASE 1 lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 lyase#PC00144;decarboxylase#PC00089 GORGO|Ensembl=ENSGGOG00000016185.3|UniProtKB=G3RJB7 G3RJB7 CPSF1 PTHR10644:SF26 DNA REPAIR/RNA PROCESSING CPSF FAMILY CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015553.3|UniProtKB=G3RHP9 G3RHP9 WRAP73 PTHR16220:SF1 WD REPEAT PROTEIN 8-RELATED WD REPEAT-CONTAINING PROTEIN WRAP73 mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;membraneless organelle assembly#GO:0140694;microtubule cytoskeleton organization involved in mitosis#GO:1902850;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;spindle assembly#GO:0051225;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000027024.2|UniProtKB=G3RW91 G3RW91 C20H19orf53 PTHR16967:SF1 LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284 GORGO|Ensembl=ENSGGOG00000012931.3|UniProtKB=G3RAX9 G3RAX9 YPEL PTHR13848:SF102 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 3 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000007204.3|UniProtKB=G3QW95 G3QW95 TMEM86A PTHR31885:SF9 GH04784P LYSOPLASMALOGENASE TMEM86A catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000024422.2|UniProtKB=G3RUS0 G3RUS0 SNAI1 PTHR24393:SF172 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 410 nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000025044.2|UniProtKB=A0A2I2YC76 A0A2I2YC76 CEP44 PTHR31477:SF1 CENTROSOMAL PROTEIN OF 44 KDA CENTROSOMAL PROTEIN OF 44 KDA cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;centriole replication#GO:0007099;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922 GORGO|Ensembl=ENSGGOG00000004610.3|UniProtKB=G3RVG5 G3RVG5 UHRF1 PTHR14140:SF2 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED E3 UBIQUITIN-PROTEIN LIGASE UHRF1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein modification by small protein conjugation or removal#GO:0070647;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002577.4|UniProtKB=G3QJE9 G3QJE9 TMEM135 PTHR12459:SF27 TRANSMEMBRANE PROTEIN 135-RELATED TRANSMEMBRANE PROTEIN 135 GORGO|Ensembl=ENSGGOG00000023849.2|UniProtKB=A0A2I2YCV1 A0A2I2YCV1 FGFR1OP2 PTHR12186:SF3 SIKE FAMILY MEMBER FGFR1 ONCOGENE PARTNER 2 response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950 GORGO|Ensembl=ENSGGOG00000027409.2|UniProtKB=G3SBD3 G3SBD3 MAP4K5 PTHR48012:SF19 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 5 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCK#P00268;Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861 GORGO|Ensembl=ENSGGOG00000027737.2|UniProtKB=G3RNM7 G3RNM7 PTHR48013:SF8 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MEK1/2#P06739;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891;VEGF signaling pathway#P00056>MEK#P01402;FGF signaling pathway#P00021>MEK1-2#P00642;Ras Pathway#P04393>MEK#P04557;Toll receptor signaling pathway#P00054>MKK2#P01368;Gonadotropin-releasing hormone receptor pathway#P06664>MAP2K1/2#P06794;Endothelin signaling pathway#P00019>MEK#P00572;B cell activation#P00010>MEK#P00383;Integrin signalling pathway#P00034>MEK#P00925;CCKR signaling map#P06959>MAP2K2#P07121;EGF receptor signaling pathway#P00018>MEK1-2#P00559;T cell activation#P00053>MEK#P01312;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MEK#P05926;Angiogenesis#P00005>MEK#P00225;PDGF signaling pathway#P00047>MEK#P01162 GORGO|Ensembl=ENSGGOG00000008217.3|UniProtKB=G3RNL6 G3RNL6 REEP3 PTHR12300:SF39 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 3 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;organelle organization#GO:0006996 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;organelle membrane#GO:0031090;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;microtubule#GO:0005874;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011155.3|UniProtKB=G3RPK8 G3RPK8 NOL11 PTHR15633:SF3 NUCLEOLAR PROTEIN 11 NUCLEOLAR PROTEIN 11 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000024724.2|UniProtKB=G3S583 G3S583 PTHR47765:SF2 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN EXONUCLEASE MUT-7 HOMOLOG GORGO|Ensembl=ENSGGOG00000015622.3|UniProtKB=G3RHW7 G3RHW7 CLPTM1L PTHR21347:SF0 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1L endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000014322.3|UniProtKB=G3REI7 G3REI7 VIL1 PTHR11977:SF35 VILLIN VILLIN-1 phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167 regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;actin filament-based process#GO:0030029;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;regulation of actin filament depolymerization#GO:0030834;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;regulation of plasma membrane bounded cell projection organization#GO:0120035;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;organelle#GO:0043226;actin cytoskeleton#GO:0015629;cell leading edge#GO:0031252;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000005270.3|UniProtKB=A0A2I2ZLG6 A0A2I2ZLG6 FAM3A PTHR14592:SF11 UNCHARACTERIZED FAM3 PROTEIN FAM3A cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000040721.1|UniProtKB=A0A2I2YCQ0 A0A2I2YCQ0 PTHR48026:SF3 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN RRM DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000028179.2|UniProtKB=G3RU49 G3RU49 NR4A3 PTHR24085:SF2 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 3 transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565 response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to peptide hormone stimulus#GO:0071375;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000007600.3|UniProtKB=G3QX96 G3QX96 AGA PTHR10188:SF50 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000022081.2|UniProtKB=G3S4P4 G3S4P4 TMPRSS11E PTHR24253:SF84 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11E serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000012488.3|UniProtKB=G3R9T7 G3R9T7 TSEN2 PTHR21227:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518;lyase activity#GO:0016829 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 GORGO|Ensembl=ENSGGOG00000008209.3|UniProtKB=G3QYT3 G3QYT3 CD101 PTHR12207:SF25 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 2 cellular anatomical structure#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000017192.3|UniProtKB=G3RLW6 G3RLW6 RFC3 PTHR11669:SF1 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 3 ATP-dependent activity#GO:0140657;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;replication fork#GO:0005657;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 GORGO|Ensembl=ENSGGOG00000012761.3|UniProtKB=G3RAH4 G3RAH4 CD200 PTHR46841:SF3 OX-2 MEMBRANE GLYCOPROTEIN OX-2 MEMBRANE GLYCOPROTEIN cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;cell adhesion#GO:0007155;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;heterotypic cell-cell adhesion#GO:0034113 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;neuron projection#GO:0043005;cell body#GO:0044297;axon#GO:0030424 GORGO|Ensembl=ENSGGOG00000009650.3|UniProtKB=G3R2H6 G3R2H6 RARS1 PTHR11956:SF5 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000043438.1|UniProtKB=A0A2I2YR54 A0A2I2YR54 SNX3 PTHR45963:SF1 RE52028P SORTING NEXIN-3 phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266 endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147 early endosome membrane#GO:0031901;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000040996.1|UniProtKB=A0A2I2ZXX3 A0A2I2ZXX3 LOC101139001 PTHR10060:SF15 TATD FAMILY DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE TATDN1 exonuclease activity#GO:0004527;hydrolase activity#GO:0016787;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000009372.3|UniProtKB=G3R1S7 G3R1S7 PTGS1 PTHR11903:SF6 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G_H SYNTHASE 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 icosanoid metabolic process#GO:0006690;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;icosanoid biosynthetic process#GO:0046456;unsaturated fatty acid biosynthetic process#GO:0006636;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;arachidonate metabolic process#GO:0019369;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;prostaglandin metabolic process#GO:0006693 cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 oxidoreductase#PC00176;oxygenase#PC00177 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cyclooxygenase#P00845 GORGO|Ensembl=ENSGGOG00000009617.3|UniProtKB=G3R2E8 G3R2E8 NCOA6 PTHR15690:SF0 NUCLEAR RECEPTOR COACTIVATOR 6 NUCLEAR RECEPTOR COACTIVATOR 6 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000041862.1|UniProtKB=A0A2I2Z0T7 A0A2I2Z0T7 PTHR23281:SF40 MERLIN/MOESIN/EZRIN/RADIXIN FERM DOMAIN-CONTAINING PROTEIN cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of anatomical structure morphogenesis#GO:0022603;regulation of transport#GO:0051049;regulation of localization#GO:0032879 membraneless organelle#GO:0043228;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;filopodium#GO:0030175;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000003682.3|UniProtKB=G3QM89 G3QM89 CEP135 PTHR23159:SF18 CENTROSOMAL PROTEIN 2 CENTROSOMAL PROTEIN OF 135 KDA centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008959.3|UniProtKB=A0A2I2Y5M4 A0A2I2Y5M4 PTHR28621:SF1 SELENOPROTEIN S SELENOPROTEIN S regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;localization#GO:0051179;cell communication#GO:0007154;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;protein transport#GO:0015031;response to unfolded protein#GO:0006986;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;response to stress#GO:0006950;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 GORGO|Ensembl=ENSGGOG00000036374.1|UniProtKB=A0A2I2Z9N8 A0A2I2Z9N8 PTHR31542:SF1 39A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML50 intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000011127.3|UniProtKB=G3R6A8 G3R6A8 ADAMTSL2 PTHR13723:SF147 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 2 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000001709.3|UniProtKB=A0A2I2ZS44 A0A2I2ZS44 VAMP7 PTHR21136:SF202 SNARE PROTEINS VESICLE ASSOCIATED MEMBRANE PROTEIN 7 protein binding#GO:0005515;SNAP receptor activity#GO:0005484;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 membrane invagination#GO:0010324;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778;exocytosis#GO:0006887;microtubule-based process#GO:0007017;vesicle organization#GO:0016050;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;autophagy#GO:0006914;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;establishment of vesicle localization#GO:0051650;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle transport along microtubule#GO:0072384;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041;post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;export from cell#GO:0140352;Golgi to plasma membrane protein transport#GO:0043001;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;phagocytosis#GO:0006909;vesicle transport along microtubule#GO:0047496;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;vesicle cytoskeletal trafficking#GO:0099518;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;vesicle localization#GO:0051648;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;endosome to lysosome transport#GO:0008333;organelle localization#GO:0051640;localization#GO:0051179;secretion#GO:0046903;Golgi organization#GO:0007030;protein localization to plasma membrane#GO:0072659;vesicle fusion#GO:0006906;Golgi to plasma membrane transport#GO:0006893;catabolic process#GO:0009056;microtubule-based movement#GO:0007018 Golgi apparatus#GO:0005794;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;lysosome#GO:0005764;vesicle#GO:0031982;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 SNARE protein#PC00034;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000027860.2|UniProtKB=G3RPQ0 G3RPQ0 RNF39 PTHR24103:SF646 E3 UBIQUITIN-PROTEIN LIGASE TRIM RING FINGER PROTEIN 39 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000011312.3|UniProtKB=A0A2I2YJR0 A0A2I2YJR0 SRL PTHR43681:SF3 TRANSMEMBRANE GTPASE FZO SARCALUMENIN transport#GO:0006810;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;metal ion transport#GO:0030001 protein-binding activity modulator#PC00095;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000003236.3|UniProtKB=G3QL37 G3QL37 LOC101125253 PTHR26450:SF23 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008078.3|UniProtKB=G3QYG7 G3QYG7 C2CD2L PTHR21119:SF8 C2 DOMAIN-CONTAINING PROTEIN PHOSPHOLIPID TRANSFER PROTEIN C2CD2L phosphatidylinositol transfer activity#GO:0008526;transporter activity#GO:0005215;phosphatidylinositol binding#GO:0035091;lipid transfer activity#GO:0120013;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 positive regulation of protein secretion#GO:0050714;regulation of transport#GO:0051049;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of insulin secretion#GO:0050796;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;regulation of signaling#GO:0023051;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of protein secretion#GO:0050708;regulation of hormone levels#GO:0010817 apical part of cell#GO:0045177;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;apical plasma membrane#GO:0016324;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000040689.1|UniProtKB=A0A2I2YTY6 A0A2I2YTY6 LOC101127721 PTHR23299:SF44 METALLOTHIONEIN METALLOTHIONEIN cation binding#GO:0043169;metal ion binding#GO:0046872;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 response to metal ion#GO:0010038;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;response to cadmium ion#GO:0046686;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;detoxification of inorganic compound#GO:0061687;response to stress#GO:0006950;detoxification#GO:0098754;response to chemical#GO:0042221;inorganic ion homeostasis#GO:0098771;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;response to stimulus#GO:0050896;response to toxic substance#GO:0009636 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000036583.1|UniProtKB=A0A2I2Z9V6 A0A2I2Z9V6 FGGY PTHR43435:SF4 RIBULOKINASE FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137;metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065;transferase#PC00220 Ascorbate degradation#P02729>L-xylulose kinase#P02849;Pentose phosphate pathway#P02762>D-Ribulo Kinase#P03077 GORGO|Ensembl=ENSGGOG00000000656.3|UniProtKB=G3QEF1 G3QEF1 PTHR23203:SF4 PROLINE-RICH PROTEIN BASIC SALIVARY PROLINE-RICH PROTEIN 3 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000005241.3|UniProtKB=G3QR89 G3QR89 TMEM232 PTHR28651:SF2 TRANSMEMBRANE PROTEIN 232 TRANSMEMBRANE PROTEIN 232 cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;sperm motility#GO:0097722;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;gamete generation#GO:0007276;cell motility#GO:0048870;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;cilium-dependent cell motility#GO:0060285 supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;sperm flagellum#GO:0036126;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000013567.3|UniProtKB=A0A2I2YSL8 A0A2I2YSL8 GUK1 PTHR23117:SF13 GUANYLATE KINASE-RELATED GUANYLATE KINASE phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleoside diphosphate metabolic process#GO:0009132;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;transferase#PC00220 De novo purine biosynthesis#P02738>Guanylate kinase#P02904 GORGO|Ensembl=ENSGGOG00000004694.3|UniProtKB=G3QPU6 G3QPU6 CIDEB PTHR12306:SF10 CELL DEATH ACTIVATOR CIDE LIPID TRANSFERASE CIDEB lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;lipid transfer activity#GO:0120013 lipid storage#GO:0019915;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;organelle organization#GO:0006996;cellular component organization#GO:0016043;programmed cell death#GO:0012501;organelle fusion#GO:0048284;lipid droplet organization#GO:0034389;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000036533.1|UniProtKB=A0A2I2ZFP8 A0A2I2ZFP8 C1GALT1 PTHR23033:SF13 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;galactosyltransferase activity#GO:0008378 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000000251.3|UniProtKB=A0A2I2YMP0 A0A2I2YMP0 STYK1 PTHR24416:SF631 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE STYK1 signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010758.3|UniProtKB=G3R5C3 G3R5C3 LRRC74A PTHR24114:SF50 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74A GORGO|Ensembl=ENSGGOG00000012751.3|UniProtKB=A0A2I2Y734 A0A2I2Y734 SLC41A1 PTHR16228:SF23 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000038077.1|UniProtKB=G3QK83 G3QK83 NLRP8 PTHR45690:SF8 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 8 regulation of response to stress#GO:0080134;regulation of biological process#GO:0050789;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of response to stimulus#GO:0048583;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000006070.3|UniProtKB=G3QTC7 G3QTC7 ZNF280D PTHR24388:SF34 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 280D sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000022261.2|UniProtKB=G3RT84 G3RT84 PTHR31077:SF7 U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27KDA PROTEIN DOMAIN-CONTAINING PROTEIN protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016053.3|UniProtKB=G3RIY9 G3RIY9 CPO PTHR11705:SF19 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE O carboxypeptidase activity#GO:0004180;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000043504.1|UniProtKB=A0A2I2YCX7 A0A2I2YCX7 STUB1 PTHR46803:SF5 E3 UBIQUITIN-PROTEIN LIGASE CHIP E3 UBIQUITIN-PROTEIN LIGASE CHIP ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein-folding chaperone binding#GO:0051087 response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of proteolysis#GO:0030162;response to misfolded protein#GO:0051788;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular response to misfolded protein#GO:0071218;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;regulation of cellular process#GO:0050794;cellular response to topologically incorrect protein#GO:0035967;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;I band#GO:0031674;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>CHIP#P01214 GORGO|Ensembl=ENSGGOG00000037693.1|UniProtKB=A0A2I2Y644 A0A2I2Y644 MS4A1 PTHR23320:SF79 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED B-LYMPHOCYTE ANTIGEN CD20 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011583.3|UniProtKB=G3R7F9 G3R7F9 ANKRD50 PTHR24123:SF65 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 50 endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015595.3|UniProtKB=G3RHU0 G3RHU0 TLL2 PTHR10127:SF866 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING TOLLOID-LIKE PROTEIN 2 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;proteolysis#GO:0006508;pattern specification process#GO:0007389;primary metabolic process#GO:0044238;dorsal/ventral pattern formation#GO:0009953;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;developmental process#GO:0032502;gene expression#GO:0010467;regionalization#GO:0003002;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000000985.3|UniProtKB=A0A2I2YGH1 A0A2I2YGH1 TMBIM4 PTHR23291:SF50 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 4 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000009821.3|UniProtKB=G3R2Y4 G3R2Y4 ALLC PTHR12045:SF3 ALLANTOICASE INACTIVE ALLANTOICASE-RELATED Allantoin degradation#P02725>Allantoate amidohydrolase#P02821 GORGO|Ensembl=ENSGGOG00000009402.3|UniProtKB=G3SAZ9 G3SAZ9 FOXM1 PTHR46878:SF1 FORKHEAD BOX PROTEIN M1 FORKHEAD BOX PROTEIN M1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to stress#GO:0006950;positive regulation of macromolecule metabolic process#GO:0010604;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA repair#GO:0045739;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;positive regulation of DNA metabolic process#GO:0051054;positive regulation of double-strand break repair#GO:2000781;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of double-strand break repair#GO:2000779;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000017117.3|UniProtKB=A0A2I2ZYF9 A0A2I2ZYF9 EFS PTHR10654:SF14 CAS SCAFFOLDING PROTEIN EMBRYONAL FYN-ASSOCIATED SUBSTRATE cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell migration#GO:0016477;cell motility#GO:0048870;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000016543.3|UniProtKB=G3RK75 G3RK75 FAM186A PTHR33590:SF2 GLUTENIN, HIGH MOLECULAR WEIGHT SUBUNIT PW212-RELATED PROTEIN PROTEIN FAM186A GORGO|Ensembl=ENSGGOG00000026861.2|UniProtKB=G3RU69 G3RU69 DAZAP2 PTHR31638:SF4 DAZ-ASSOCIATED PROTEIN 2 DAZ-ASSOCIATED PROTEIN 2 GORGO|Ensembl=ENSGGOG00000039661.1|UniProtKB=A0A2I2Z776 A0A2I2Z776 PTHR23226:SF363 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005846.3|UniProtKB=G3QSS9 G3QSS9 RNASEH2A PTHR10954:SF7 RIBONUCLEASE H2 SUBUNIT A RIBONUCLEASE H2 SUBUNIT A hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540 cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;mismatch repair#GO:0006298;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 endoribonuclease#PC00094 DNA replication#P00017>RNase H#P00538 GORGO|Ensembl=ENSGGOG00000008804.3|UniProtKB=G3R0D7 G3R0D7 ABCA4 PTHR19229:SF190 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA RETINAL-SPECIFIC PHOSPHOLIPID-TRANSPORTING ATPASE ABCA4 intramembrane lipid carrier activity#GO:0140303;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000001968.3|UniProtKB=G3SJH4 G3SJH4 ASPN PTHR45712:SF2 AGAP008170-PA ASPORIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007557.3|UniProtKB=G3QX59 G3QX59 TIGIT PTHR47734:SF1 T-CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS PROTEIN, TIGIT T-CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 positive regulation of biosynthetic process#GO:0009891;negative regulation of T cell activation#GO:0050868;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;negative regulation of multicellular organismal process#GO:0051241;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cell activation#GO:0050866;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of metabolic process#GO:0009892;regulation of lymphocyte activation#GO:0051249;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;negative regulation of gene expression#GO:0010629;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000025068.3|UniProtKB=G3SH19 G3SH19 KHDRBS2 PTHR11208:SF34 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000011425.3|UniProtKB=G3R717 G3R717 PLEKHD1 PTHR14383:SF1 SWAP-70 RECOMBINASE PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY D MEMBER 1 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007812.3|UniProtKB=A0A2I2Z2V4 A0A2I2Z2V4 NELL2 PTHR24042:SF0 NEL HOMOLOG PROTEIN KINASE C-BINDING PROTEIN NELL2 heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;glycosaminoglycan binding#GO:0005539;kinase binding#GO:0019900;binding#GO:0005488 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000034929.2|UniProtKB=G3SKR7 G3SKR7 ACSM1 PTHR43605:SF5 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM1, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000016159.3|UniProtKB=G3RJ82 G3RJ82 TMEM249 PTHR35442:SF1 TRANSMEMBRANE PROTEIN 249 CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT THETA GORGO|Ensembl=ENSGGOG00000013777.3|UniProtKB=G3RD40 G3RD40 CTDNEP1 PTHR12210:SF140 DULLARD PROTEIN PHOSPHATASE CTD NUCLEAR ENVELOPE PHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000013488.3|UniProtKB=G3RCD3 G3RCD3 AFM PTHR11385:SF18 SERUM ALBUMIN-RELATED AFAMIN heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;binding#GO:0005488 response to stimulus#GO:0050896;localization#GO:0051179;establishment of localization#GO:0051234;vitamin transport#GO:0051180;transport#GO:0006810;response to nutrient levels#GO:0031667 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000043413.1|UniProtKB=G3QR86 G3QR86 LILRA5 PTHR11738:SF194 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 5 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of immune response#GO:0050776;cytokine-mediated signaling pathway#GO:0019221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000022679.2|UniProtKB=G3S9G3 G3S9G3 SRSF8 PTHR23147:SF14 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 8 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000003788.3|UniProtKB=G3QMI1 G3QMI1 PTHR46311:SF1 CALCIUM-BINDING PROTEIN 8-RELATED CALCIUM-BINDING PROTEIN 7 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000003551.3|UniProtKB=G3QLW5 G3QLW5 ADNP2 PTHR15740:SF2 NEUROPROTECTIVE PEPTIDE-CONTAINING PROTEIN ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN 2 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001548.3|UniProtKB=A0A2I2Z450 A0A2I2Z450 SLC66A3 PTHR12226:SF3 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED SOLUTE CARRIER FAMILY 66 MEMBER 3 GORGO|Ensembl=ENSGGOG00000022765.2|UniProtKB=G3RZZ0 G3RZZ0 LOC101144860 PTHR10177:SF67 CYCLINS G1_S-SPECIFIC CYCLIN-D1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of biological process#GO:0048518;cell cycle G1/S phase transition#GO:0044843;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 kinase activator#PC00138 CCKR signaling map#P06959>CCND1#G07280;CCKR signaling map#P06959>CCND1#G06986;Cell cycle#P00013>Cyclin D#P00484;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;PI3 kinase pathway#P00048>Cyclin d#G01546 GORGO|Ensembl=ENSGGOG00000039537.1|UniProtKB=A0A2I2ZMA5 A0A2I2ZMA5 PCDH15 PTHR24028:SF11 CADHERIN-87A PROTOCADHERIN-15 sensory perception of sound#GO:0007605;visual perception#GO:0007601;multicellular organismal process#GO:0032501;sensory perception of light stimulus#GO:0050953;cellular process#GO:0009987;system process#GO:0003008;sensory perception of mechanical stimulus#GO:0050954;cell adhesion#GO:0007155;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;plasma membrane#GO:0005886;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;cell junction#GO:0030054 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000010624.3|UniProtKB=A0A2I2YCV5 A0A2I2YCV5 DERL2 PTHR11009:SF5 DER1-LIKE PROTEIN, DERLIN DERLIN-2 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000014237.3|UniProtKB=A0A2I2ZB33 A0A2I2ZB33 TDP2 PTHR15822:SF28 TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN TYROSYL-DNA PHOSPHODIESTERASE 2 hydrolase activity#GO:0016787;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000023697.2|UniProtKB=G3S862 G3S862 AMIGO1 PTHR24368:SF1 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 1 transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 brain development#GO:0007420;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;head development#GO:0060322;nervous system development#GO:0007399;cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell body#GO:0044297;membrane#GO:0016020;membrane protein complex#GO:0098796 GORGO|Ensembl=ENSGGOG00000002783.3|UniProtKB=G3QJY2 G3QJY2 PIK3R5 PTHR15593:SF2 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 5 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;G protein-coupled receptor signaling pathway#GO:0007186;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane protein complex#GO:0098796;extrinsic component of membrane#GO:0019898;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;EGF receptor signaling pathway#P00018>PI3K#P00557;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168;p53 pathway feedback loops 2#P04398>PI3K#P04661;PI3 kinase pathway#P00048>p101#P01203;Axon guidance mediated by netrin#P00009>PI3K#P00363 GORGO|Ensembl=ENSGGOG00000014310.3|UniProtKB=G3REG8 G3REG8 OR6T1 PTHR26454:SF165 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6T1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003312.3|UniProtKB=G3QLA4 G3QLA4 PDE12 PTHR12121:SF37 CARBON CATABOLITE REPRESSOR PROTEIN 4 2',5'-PHOSPHODIESTERASE 12 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527 regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000010179.3|UniProtKB=G3R3V3 G3R3V3 PNPLA8 PTHR24185:SF10 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;A2-type glycerophospholipase activity#GO:0004623;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824 cellular process#GO:0009987;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;long-chain fatty acid metabolic process#GO:0001676;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;icosanoid metabolic process#GO:0006690;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;fatty acid metabolic process#GO:0006631 membrane#GO:0016020;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phospholipase#PC00186;lipase#PC00143 GORGO|Ensembl=ENSGGOG00000015085.4|UniProtKB=G3RGH7 G3RGH7 SEMA3A PTHR11036:SF23 SEMAPHORIN SEMAPHORIN-3A binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;developmental process#GO:0032502;neural crest cell development#GO:0014032;tissue development#GO:0009888;cell migration#GO:0016477;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;stem cell differentiation#GO:0048863;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;locomotion#GO:0040011;animal organ development#GO:0048513;cell projection morphogenesis#GO:0048858;mesenchymal cell differentiation#GO:0048762;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neural crest cell differentiation#GO:0014033;response to chemical#GO:0042221;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;motor neuron axon guidance#GO:0008045;mesenchyme development#GO:0060485;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;stem cell development#GO:0048864;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;taxis#GO:0042330;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;neural crest cell migration#GO:0001755;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell development#GO:0048468;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 extracellular region#GO:0005576;axon#GO:0030424;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202 membrane-bound signaling molecule#PC00152 Axon guidance mediated by semaphorins#P00007>Sema3A#P00337 GORGO|Ensembl=ENSGGOG00000011642.3|UniProtKB=G3QZ33 G3QZ33 PTHR45991:SF1 PACHYTENE CHECKPOINT PROTEIN 2 PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;homologous recombination#GO:0035825;reproductive process#GO:0022414;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;primary metabolic process#GO:0044238;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of reproductive process#GO:2000241;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000009572.3|UniProtKB=G3R2A4 G3R2A4 DRAM2 PTHR21324:SF10 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 2 retina homeostasis#GO:0001895;multicellular organismal-level homeostasis#GO:0048871;regulation of catabolic process#GO:0009894;tissue homeostasis#GO:0001894;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789 lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006987.3|UniProtKB=G3QVQ8 G3QVQ8 COPE PTHR10805:SF0 COATOMER SUBUNIT EPSILON COATOMER SUBUNIT EPSILON localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810 coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000036864.1|UniProtKB=A0A2I2ZYI1 A0A2I2ZYI1 PTHR13110:SF7 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;P-body#GO:0000932;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000007400.3|UniProtKB=G3QWS4 G3QWS4 LYPD6 PTHR31171:SF0 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6 LY6_PLAUR DOMAIN-CONTAINING PROTEIN 6 acetylcholine receptor regulator activity#GO:0030548;signaling receptor regulator activity#GO:0030545;neurotransmitter receptor regulator activity#GO:0099602;molecular function regulator activity#GO:0098772 GORGO|Ensembl=ENSGGOG00000005080.3|UniProtKB=G3S2A0 G3S2A0 LRRC75A PTHR39654:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75A-LIKE ISOFORM X1 LEUCINE RICH REPEAT CONTAINING 75A GORGO|Ensembl=ENSGGOG00000002170.4|UniProtKB=A0A2I2ZI00 A0A2I2ZI00 TNFRSF10A PTHR46330:SF13 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10A-RELATED positive regulation of apoptotic process#GO:0043065;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;apoptotic signaling pathway#GO:0097190;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;biological regulation#GO:0065007;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell communication#GO:0007154;signaling#GO:0023052;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TRAIL-R#P00276;p53 pathway#P00059>KILLER/DR5#G01568 GORGO|Ensembl=ENSGGOG00000007374.3|UniProtKB=G3QWQ0 G3QWQ0 MSMP PTHR10500:SF4 BETA-MICROSEMINOPROTEIN PROSTATE-ASSOCIATED MICROSEMINOPROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000010653.3|UniProtKB=G3R516 G3R516 LOC101140641 PTHR19944:SF44 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DO ALPHA CHAIN protein-containing complex binding#GO:0044877;peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of leukocyte activation#GO:0002696;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of cellular process#GO:0048522;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785 late endosome membrane#GO:0031902;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 GORGO|Ensembl=ENSGGOG00000014935.3|UniProtKB=G3RG37 G3RG37 CCNE2 PTHR10177:SF70 CYCLINS G1_S-SPECIFIC CYCLIN-E2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic cell cycle phase transition#GO:0044772;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;positive regulation of biological process#GO:0048518;cell cycle G1/S phase transition#GO:0044843;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 kinase activator#PC00138 Parkinson disease#P00049>Cyclin E#P01213;Cell cycle#P00013>CdkC#P00489 GORGO|Ensembl=ENSGGOG00000014562.3|UniProtKB=G3RF47 G3RF47 CA7 PTHR18952:SF124 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 7 catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000027067.2|UniProtKB=G3S631 G3S631 TUBB4A PTHR11588:SF253 TUBULIN TUBULIN BETA-4A CHAIN ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 tubulin#PC00228;cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 GORGO|Ensembl=ENSGGOG00000014536.3|UniProtKB=A0A2I2ZX05 A0A2I2ZX05 KCTD7 PTHR14499:SF122 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of membrane potential#GO:0042391;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001200.3|UniProtKB=A0A2I2Y5E8 A0A2I2Y5E8 APOO PTHR14564:SF2 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT MIC26 membrane organization#GO:0061024;mitochondrion organization#GO:0007005;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000027430.2|UniProtKB=A0A2I2YEI7 A0A2I2YEI7 PTHR13999:SF26 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN IFITM2 negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;response to peptide#GO:1901652;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to type II interferon#GO:0034341;cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;response to virus#GO:0009615;cell communication#GO:0007154;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014633.3|UniProtKB=G3S1K3 G3S1K3 PTHR16866:SF5 GASTRIN-RELEASING PEPTIDE NEUROMEDIN-B protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of localization#GO:0032879;regulation of transport#GO:0051049;response to external stimulus#GO:0009605;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000038169.1|UniProtKB=A0A2I2ZSK9 A0A2I2ZSK9 PTHR10105:SF3 SELENOPROTEIN P SELENOPROTEIN P cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000004141.3|UniProtKB=A0A2I2ZJ01 A0A2I2ZJ01 TNNT3 PTHR11521:SF4 TROPONIN T TROPONIN T, FAST SKELETAL MUSCLE binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;neuromuscular process#GO:0050905;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;striated muscle contraction#GO:0006941;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;cellular developmental process#GO:0048869;system process#GO:0003008;developmental process#GO:0032502;muscle contraction#GO:0006936;multicellular organismal process#GO:0032501;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;nervous system process#GO:0050877;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;skeletal muscle contraction#GO:0003009;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000001996.3|UniProtKB=A0A2I2Y2E7 A0A2I2Y2E7 KIF5A PTHR24115:SF937 KINESIN-RELATED KINESIN HEAVY CHAIN ISOFORM 5A polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774 establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;axonal transport#GO:0098930;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;anterograde axonal transport#GO:0008089;axo-dendritic transport#GO:0008088;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000015401.3|UniProtKB=G3RHB2 G3RHB2 ACOT9 PTHR12655:SF10 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;deacylase activity#GO:0160215;hydrolase activity#GO:0016787 purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000013806.3|UniProtKB=A0A2I2Z4H8 A0A2I2Z4H8 MERTK PTHR24416:SF257 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE MER transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199 animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell motility#GO:0048870;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;phagocytosis#GO:0006909;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;import into cell#GO:0098657;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;cell migration#GO:0016477;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010740.3|UniProtKB=G3R5A8 G3R5A8 PCOLCE PTHR24251:SF24 OVOCHYMASE-RELATED PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER 1 peptidase regulator activity#GO:0061134;collagen binding#GO:0005518;binding#GO:0005488;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000000751.3|UniProtKB=A0A2I2Y6Q6 A0A2I2Y6Q6 TLE1 PTHR10814:SF29 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 1 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 GORGO|Ensembl=ENSGGOG00000015032.3|UniProtKB=G3RGE7 G3RGE7 ALS2 PTHR46089:SF3 ALSIN HOMOLOG ALSIN GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197 dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477 GORGO|Ensembl=ENSGGOG00000011899.3|UniProtKB=G3R8A7 G3R8A7 HSF4 PTHR10015:SF213 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000012964.3|UniProtKB=G3RB14 G3RB14 STAP2 PTHR16186:SF11 SIGNAL-TRANSDUCING ADAPTOR PROTEIN-RELATED SIGNAL-TRANSDUCING ADAPTOR PROTEIN 2 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001983.3|UniProtKB=A0A2I2YCN0 A0A2I2YCN0 STK24 PTHR48012:SF22 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 24 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of locomotion#GO:0040012;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006809.3|UniProtKB=A0A2I2Y559 A0A2I2Y559 C1H1orf105 PTHR39410:SF1 RIKEN CDNA 4930558K02 GENE RIKEN CDNA 4930558K02 GENE GORGO|Ensembl=ENSGGOG00000002822.3|UniProtKB=G3QK19 G3QK19 APC2 PTHR12607:SF3 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY ADENOMATOUS POLYPOSIS COLI PROTEIN 2 beta-catenin binding#GO:0008013;protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 multicellular organism development#GO:0007275;cell fate specification#GO:0001708;nervous system development#GO:0007399;negative regulation of signal transduction#GO:0009968;regulation of microtubule cytoskeleton organization#GO:0070507;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;regulation of canonical Wnt signaling pathway#GO:0060828;cell fate commitment#GO:0045165;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;animal gross anatomical part developmental process#GO:0160108;regulation of Wnt signaling pathway#GO:0030111;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of protein depolymerization#GO:1901880;negative regulation of Wnt signaling pathway#GO:0030178;cell migration#GO:0016477;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;system development#GO:0048731;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;regulation of microtubule-based process#GO:0032886;regulation of cell communication#GO:0010646;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129 cytoskeleton#GO:0005856;intracellular protein-containing complex#GO:0140535;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Wnt signaling pathway#P00057>APC#P01468;Angiogenesis#P00005>APC#P00195 GORGO|Ensembl=ENSGGOG00000037744.1|UniProtKB=G3RCH0 G3RCH0 LOC109027175 PTHR19944:SF94 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ ALPHA 2 CHAIN protein-containing complex binding#GO:0044877;peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;regulation of immune response#GO:0050776;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694 lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 GORGO|Ensembl=ENSGGOG00000008785.3|UniProtKB=G3R0A5 G3R0A5 RASL11A PTHR45704:SF3 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11A GORGO|Ensembl=ENSGGOG00000026651.2|UniProtKB=G3S3I4 G3S3I4 ATAD1 PTHR45644:SF2 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED OUTER MITOCHONDRIAL TRANSMEMBRANE HELIX TRANSLOCASE cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;localization within membrane#GO:0051668;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150 GORGO|Ensembl=ENSGGOG00000010165.3|UniProtKB=A0A2I2ZTT0 A0A2I2ZTT0 CABP2 PTHR45917:SF2 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 2 transporter regulator activity#GO:0141108;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 sensory perception of light stimulus#GO:0050953;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;sensory perception of sound#GO:0007605;visual perception#GO:0007601;signaling#GO:0023052;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;cell communication#GO:0007154;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;system process#GO:0003008;response to external stimulus#GO:0009605 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000002156.3|UniProtKB=G3QIB6 G3QIB6 RMDN3 PTHR16056:SF18 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 3 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 spindle pole#GO:0000922;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;spindle#GO:0005819;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000001325.3|UniProtKB=G3QG57 G3QG57 CLUL1 PTHR10970:SF2 CLUSTERIN CLUSTERIN-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000005550.3|UniProtKB=G3S6R6 G3S6R6 LCOR PTHR14931:SF2 GENE 340-RELATED LIGAND DEPENDENT NUCLEAR RECEPTOR COREPRESSOR GORGO|Ensembl=ENSGGOG00000016859.3|UniProtKB=A0A2I2ZXW0 A0A2I2ZXW0 DZIP1 PTHR21502:SF5 ZINC FINGER PROTEIN DZIP1 CILIUM ASSEMBLY PROTEIN DZIP1 protein-containing complex binding#GO:0044877;molecular sequestering activity#GO:0140313;binding#GO:0005488;protein sequestering activity#GO:0140311 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000011412.3|UniProtKB=A0A2I2ZFC5 A0A2I2ZFC5 AGO2 PTHR22891:SF59 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;single-stranded RNA binding#GO:0003727;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;nuclease activity#GO:0004518 RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000006452.3|UniProtKB=G3QUB1 G3QUB1 CIBAR1 PTHR21223:SF4 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 1 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;ciliary transition zone#GO:0035869;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000042374.1|UniProtKB=G3QP35 G3QP35 PTHR23075:SF5 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3A mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000008902.4|UniProtKB=G3R0L8 G3R0L8 FUT8 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 GORGO|Ensembl=ENSGGOG00000015637.3|UniProtKB=G3RHX6 G3RHX6 SLC51B PTHR36129:SF1 ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA macromolecule localization#GO:0033036;lipid transport#GO:0006869;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008612.3|UniProtKB=G3S9N6 G3S9N6 AREL1 PTHR11254:SF340 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE APOPTOSIS-RESISTANT E3 UBIQUITIN PROTEIN LIGASE 1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000028442.2|UniProtKB=G3SB87 G3SB87 ZBTB18 PTHR24394:SF18 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 18 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000023907.2|UniProtKB=G3S3J2 G3S3J2 COL10A1 PTHR24023:SF880 COLLAGEN ALPHA COLLAGEN ALPHA-1(X) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000001827.3|UniProtKB=G3SJA5 G3SJA5 ACVR2B PTHR23255:SF70 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-2B kinase activity#GO:0016301;activin binding#GO:0048185;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;activin receptor signaling pathway#GO:0032924;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;multicellular organism development#GO:0007275 protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;signaling receptor complex#GO:0043235;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII/IIB#P06780;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277 GORGO|Ensembl=ENSGGOG00000026395.2|UniProtKB=G3S1B3 G3S1B3 PTHR11691:SF70 TYPE I INTERFERON INTERFERON ALPHA-2 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;protein binding#GO:0005515 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;lymphocyte activation involved in immune response#GO:0002285;cellular process#GO:0009987;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;T cell activation involved in immune response#GO:0002286;humoral immune response#GO:0006959;natural killer cell activation#GO:0030101;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;B cell activation#GO:0042113;T cell activation#GO:0042110;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;immune response#GO:0006955;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;response to other organism#GO:0051707;adaptive immune response#GO:0002250;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;cell activation#GO:0001775;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interferon superfamily#PC00127;cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000000648.3|UniProtKB=G3QEE4 G3QEE4 RPL12 PTHR11661:SF51 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11 RNA binding#GO:0003723;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003856.3|UniProtKB=G3QMP1 G3QMP1 SLC27A3 PTHR43107:SF12 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 3 ligase activity, forming carbon-sulfur bonds#GO:0016877;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;monocarboxylic acid transmembrane transporter activity#GO:0008028;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;transporter activity#GO:0005215 monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;import into cell#GO:0098657;establishment of localization#GO:0051234;lipid metabolic process#GO:0006629;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid transport#GO:0006869;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000010157.3|UniProtKB=G3R3T2 G3R3T2 KRT18 PTHR23239:SF349 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 18 cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;intermediate filament-based process#GO:0045103 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000006646.3|UniProtKB=G3QUV3 G3QUV3 OGDHL PTHR23152:SF5 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE-LIKE, MITOCHONDRIAL oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mitochondrion#GO:0005739;cytosol#GO:0005829;oxidoreductase complex#GO:1990204;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000027550.2|UniProtKB=G3S6U4 G3S6U4 FAM174C PTHR28607:SF2 EXPRESSED PROTEIN PROTEIN FAM174C cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000004470.3|UniProtKB=G3SA68 G3SA68 FAM98C PTHR31353:SF10 FAM98 PROTEIN FAM98C protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000007802.3|UniProtKB=G3QXS1 G3QXS1 VAPB PTHR10809:SF12 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN B_C protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum membrane organization#GO:0090158;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;organelle organization#GO:0006996;membrane organization#GO:0061024;endomembrane system organization#GO:0010256 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000006885.3|UniProtKB=G3SJL5 G3SJL5 TRIM41 PTHR24103:SF713 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM41 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012464.3|UniProtKB=G3R9R9 G3R9R9 SULF1 PTHR43108:SF1 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;positive regulation of cellular process#GO:0048522;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of macromolecule metabolic process#GO:0010604;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteoglycan metabolic process#GO:0006029 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000011537.3|UniProtKB=A0A2I2YUM9 A0A2I2YUM9 SENP3 PTHR12606:SF16 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 3 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190 GORGO|Ensembl=ENSGGOG00000015640.3|UniProtKB=G3RHX9 G3RHX9 SNRPD3 PTHR23338:SF17 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D3 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;spliceosomal snRNP assembly#GO:0000387;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 catalytic step 2 spliceosome#GO:0071013;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;cytoplasm#GO:0005737;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007168.3|UniProtKB=G3S701 G3S701 CERS3 PTHR12560:SF18 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 3 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001272.3|UniProtKB=A0A2I2Z2N4 A0A2I2Z2N4 WNT5B PTHR12027:SF87 WNT RELATED PROTEIN WNT-5B receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 system development#GO:0048731;cell fate commitment#GO:0045165;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 GORGO|Ensembl=ENSGGOG00000000778.3|UniProtKB=G3QER8 G3QER8 PRTN3 PTHR24257:SF15 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER MYELOBLASTIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000007221.3|UniProtKB=G3QWB3 G3QWB3 EGR4 PTHR23235:SF58 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007031.4|UniProtKB=G3QVU4 G3QVU4 AFMID PTHR23024:SF574 ARYLACETAMIDE DEACETYLASE KYNURENINE FORMAMIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 deacetylase#PC00087 GORGO|Ensembl=ENSGGOG00000011369.3|UniProtKB=G3R6W1 G3R6W1 IMPA2 PTHR20854:SF29 INOSITOL MONOPHOSPHATASE INOSITOL MONOPHOSPHATASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000036891.1|UniProtKB=G3QGY2 G3QGY2 MYH1 PTHR45615:SF2 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543 muscle contraction#GO:0006936;muscle system process#GO:0003012;multicellular organismal process#GO:0032501;system process#GO:0003008 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 GORGO|Ensembl=ENSGGOG00000014892.3|UniProtKB=G3RG48 G3RG48 SYNE1 PTHR47535:SF9 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 nuclear migration#GO:0007097;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of organelle localization#GO:0051656;transport#GO:0006810;intracellular transport#GO:0046907;organelle localization#GO:0051640;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 membrane#GO:0016020;nucleus#GO:0005634;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;nuclear protein-containing complex#GO:0140513;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000006389.3|UniProtKB=G3QU55 G3QU55 KLK4 PTHR24271:SF65 KALLIKREIN-RELATED KALLIKREIN-4 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein maturation#GO:0051604;gene expression#GO:0010467;odontogenesis of dentin-containing tooth#GO:0042475;biosynthetic process#GO:0009058;amelogenesis#GO:0097186;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;anatomical structure formation involved in morphogenesis#GO:0048646;metabolic process#GO:0008152;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;odontogenesis#GO:0042476;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;anatomical structure morphogenesis#GO:0009653;cellular component disassembly#GO:0022411;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;extracellular region#GO:0005576;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000014806.3|UniProtKB=A0A2I2YGW8 A0A2I2YGW8 URM1 PTHR14986:SF4 RURM1 PROTEIN UBIQUITIN-RELATED MODIFIER 1 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000016927.3|UniProtKB=G3RL79 G3RL79 LOC101131791 PTHR11467:SF21 HISTONE H1 HISTONE H1.10 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490 chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000013270.3|UniProtKB=G3RBS9 G3RBS9 LOC101147293 PTHR28578:SF2 MITOTIC-SPINDLE ORGANIZING PROTEIN 2A-RELATED MITOTIC-SPINDLE ORGANIZING PROTEIN 2A organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000043837.1|UniProtKB=A0A2I2YHE2 A0A2I2YHE2 PTHR28599:SF2 SMALL INTEGRAL MEMBRANE PROTEIN 12 SMALL INTEGRAL MEMBRANE PROTEIN 12 GORGO|Ensembl=ENSGGOG00000041289.1|UniProtKB=A0A2I2YLU0 A0A2I2YLU0 PTHR45699:SF4 60S ACIDIC RIBOSOMAL PROTEIN P0 LARGE RIBOSOMAL SUBUNIT PROTEIN UL10-LIKE INSERTION DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009710.3|UniProtKB=G3R2M8 G3R2M8 PRSS16 PTHR11010:SF123 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED THYMUS-SPECIFIC SERINE PROTEASE endosome#GO:0005768;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000016174.3|UniProtKB=G3SE10 G3SE10 SHFL PTHR16135:SF2 REPRESSOR OF YIELD OF DENV PROTEIN SHIFTLESS ANTIVIRAL INHIBITOR OF RIBOSOMAL FRAMESHIFTING PROTEIN ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546 GORGO|Ensembl=ENSGGOG00000013984.3|UniProtKB=A0A2I2YCX4 A0A2I2YCX4 RGS5 PTHR10845:SF42 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 5 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of cell communication#GO:0010648;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 GORGO|Ensembl=ENSGGOG00000010094.3|UniProtKB=G3R3L9 G3R3L9 OR51G2 PTHR26450:SF133 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51G2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000358.3|UniProtKB=A0A2I2Y832 A0A2I2Y832 SCN2A PTHR10037:SF278 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 2 SUBUNIT ALPHA monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272 system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;nervous system process#GO:0050877;sensory perception#GO:0007600;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;sodium ion transport#GO:0006814;action potential#GO:0001508;sensory perception of pain#GO:0019233 cation channel complex#GO:0034703;transporter complex#GO:1990351;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;axon#GO:0030424;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000024283.2|UniProtKB=G3S8I8 G3S8I8 MAGEB6 PTHR11736:SF139 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B6 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007978.3|UniProtKB=G3QY66 G3QY66 LOC101153294 PTHR26450:SF164 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014105.3|UniProtKB=G3RE01 G3RE01 TSPAN3 PTHR19282:SF48 TETRASPANIN TETRASPANIN-3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000041772.1|UniProtKB=A0A2I2Z183 A0A2I2Z183 ZNF682 PTHR24384:SF116 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 682 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000017096.3|UniProtKB=G3S633 G3S633 SYT13 PTHR10024:SF250 SYNAPTOTAGMIN SYNAPTOTAGMIN-13 protein binding#GO:0005515;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;secretion#GO:0046903;regulation of exocytosis#GO:0017157;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;positive regulation of transport#GO:0051050;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;positive regulation of vesicle fusion#GO:0031340;regulated exocytosis#GO:0045055;regulation of cellular component organization#GO:0051128;regulation of neurotransmitter secretion#GO:0046928;signaling#GO:0023052;export from cell#GO:0140352;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051 plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;axon#GO:0030424;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular vesicle#GO:0097708;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000014542.3|UniProtKB=G3RF36 G3RF36 LAMC2 PTHR10574:SF313 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-2 anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;tissue development#GO:0009888;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cellular process#GO:0009987 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000000604.3|UniProtKB=G3QEA2 G3QEA2 THUMPD3 PTHR14911:SF13 THUMP DOMAIN-CONTAINING TRNA (GUANINE(6)-N(2))-METHYLTRANSFERASE THUMP3 RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000028604.2|UniProtKB=G3S0R8 G3S0R8 IGFN1 PTHR13817:SF138 TITIN IMMUNOGLOBULIN-LIKE AND FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000002772.3|UniProtKB=G3QJX2 G3QJX2 INHBE PTHR11848:SF6 TGF-BETA FAMILY INHIBIN BETA E CHAIN signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000006583.3|UniProtKB=G3QUN4 G3QUN4 PFDN6 PTHR21431:SF0 PREFOLDIN SUBUNIT 6 PREFOLDIN SUBUNIT 6 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000024533.2|UniProtKB=G3RZI6 G3RZI6 LOC101150625 PTHR21859:SF44 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31C1-RELATED GORGO|Ensembl=ENSGGOG00000009532.3|UniProtKB=G3R271 G3R271 TBL1XR1 PTHR22846:SF40 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1XR1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transcription repressor complex#GO:0017053;protein-containing complex#GO:0032991;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233 Wnt signaling pathway#P00057>Ebi#P01453 GORGO|Ensembl=ENSGGOG00000001982.4|UniProtKB=G3QHW7 G3QHW7 MARS1 PTHR45765:SF1 METHIONINE--TRNA LIGASE METHIONINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 catalytic complex#GO:1902494;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000040672.1|UniProtKB=A0A2I2Z6S5 A0A2I2Z6S5 PTHR10715:SF11 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008573.3|UniProtKB=A0A2I2ZIP8 A0A2I2ZIP8 SPC24 PTHR22142:SF2 KINETOCHORE PROTEIN SPC24 KINETOCHORE PROTEIN SPC24 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cell cycle process#GO:0022402;cellular process#GO:0009987;chromosome segregation#GO:0007059;cell cycle#GO:0007049 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;membraneless organelle#GO:0043228;outer kinetochore#GO:0000940;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007195.3|UniProtKB=G3QW98 G3QW98 CCDC13 PTHR31935:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cytoplasmic microtubule organization#GO:0031122;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;non-motile cilium assembly#GO:1905515;organelle assembly#GO:0070925 GORGO|Ensembl=ENSGGOG00000038822.1|UniProtKB=A0A2I2Z1B7 A0A2I2Z1B7 IRS4 PTHR10614:SF2 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 4 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971 cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to oxygen-containing compound#GO:1901700;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899 GORGO|Ensembl=ENSGGOG00000041773.1|UniProtKB=A0A2I2Y695 A0A2I2Y695 ZNF43 PTHR23226:SF313 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 93 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000038298.1|UniProtKB=A0A2I2Y1T3 A0A2I2Y1T3 LOC101133227 PTHR10288:SF93 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 2 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;negative regulation of catabolic process#GO:0009895;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001551.3|UniProtKB=G3QGS0 G3QGS0 ANOS1 PTHR14131:SF5 ANOSMIN ANOSMIN-1 neurogenesis#GO:0022008;system development#GO:0048731;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;cellular process#GO:0009987 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000010546.3|UniProtKB=G3R4R9 G3R4R9 ADRA2C PTHR24248:SF25 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2C ADRENERGIC RECEPTOR cation binding#GO:0043169;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;hormone binding#GO:0042562 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 GORGO|Ensembl=ENSGGOG00000023221.2|UniProtKB=A0A2I2ZG32 A0A2I2ZG32 PTHR21139:SF23 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside diphosphate catabolic process#GO:0009134;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;aldehyde metabolic process#GO:0006081;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;oxoacid metabolic process#GO:0043436;glyceraldehyde-3-phosphate metabolic process#GO:0019682;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052 metabolite interconversion enzyme#PC00262;isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000007914.3|UniProtKB=G3QY18 G3QY18 ODAM PTHR16237:SF3 ODONTOGENIC AMELOBLAST-ASSOCIATED PROTEIN ODONTOGENIC AMELOBLAST-ASSOCIATED PROTEIN animal organ development#GO:0048513;developmental process#GO:0032502;biological regulation#GO:0065007;odontogenesis of dentin-containing tooth#GO:0042475;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;response to stress#GO:0006950;response to wounding#GO:0009611;wound healing#GO:0042060;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;positive regulation of epithelial cell proliferation#GO:0050679;odontogenesis#GO:0042476;response to stimulus#GO:0050896;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell population proliferation#GO:0008284 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009889.3|UniProtKB=G3SFL8 G3SFL8 RNF34 PTHR14879:SF3 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF34 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 regulation of apoptotic process#GO:0042981;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;negative regulation of signaling#GO:0023057;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;protein metabolic process#GO:0019538;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of extrinsic apoptotic signaling pathway#GO:2001236 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000003939.3|UniProtKB=G3QMX5 G3QMX5 ANK3 PTHR24123:SF49 ANKYRIN REPEAT-CONTAINING ANKYRIN-2 ISOFORM X1 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011698.3|UniProtKB=G3R7Q9 G3R7Q9 LOC101154261 PTHR23147:SF80 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 4B rhythmic process#GO:0048511;circadian rhythm#GO:0007623 nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000015749.3|UniProtKB=G3RI71 G3RI71 NAIP PTHR46914:SF1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;detection of stimulus#GO:0051606;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of apoptotic process#GO:0042981;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;defense response to bacterium#GO:0042742;inflammatory response#GO:0006954;response to bacterium#GO:0009617 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;canonical inflammasome complex#GO:0061702 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000000787.3|UniProtKB=G3QES7 G3QES7 CTSE PTHR47966:SF26 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CATHEPSIN E aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;immune system process#GO:0002376;macromolecule metabolic process#GO:0043170;antigen processing and presentation#GO:0019882;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 aspartic protease#PC00053;protease#PC00190 GORGO|Gene=NDUFA3|UniProtKB=Q0MQ95 Q0MQ95 NDUFA3 PTHR15221:SF0 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 3 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 3 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000003572.3|UniProtKB=G3QLY7 G3QLY7 LARP4B PTHR22792:SF43 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 4B mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000022917.2|UniProtKB=G3SKC5 G3SKC5 PTHR22422:SF6 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5B-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 188 GORGO|Ensembl=ENSGGOG00000027208.2|UniProtKB=G3SEM1 G3SEM1 LOC101145975 PTHR12411:SF902 CYSTEINE PROTEASE FAMILY C1-RELATED PROCATHEPSIN L catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000025352.2|UniProtKB=G3SGJ6 G3SGJ6 LOC101129974 PTHR23226:SF300 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 852 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004483.3|UniProtKB=G3QPA5 G3QPA5 FAM9A PTHR19368:SF16 XLR/SCP3/FAM9 PROTEIN FAM9A cellular process#GO:0009987;male gamete generation#GO:0048232;meiotic cell cycle#GO:0051321;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;developmental process involved in reproduction#GO:0003006;cell cycle#GO:0007049;germ cell development#GO:0007281;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609 condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000013131.3|UniProtKB=G3RBF7 G3RBF7 SLC6A17 PTHR11616:SF102 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER SLC6A17 carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;alanine transport#GO:0032328;establishment of localization#GO:0051234;branched-chain amino acid transport#GO:0015803;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;glycine transport#GO:0015816;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;L-leucine transport#GO:0015820 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;cell junction#GO:0030054 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 GORGO|Ensembl=ENSGGOG00000038713.1|UniProtKB=A0A2I2YZY6 A0A2I2YZY6 PTHR10934:SF12 60S RIBOSOMAL PROTEIN L18 LARGE RIBOSOMAL SUBUNIT PROTEIN UL15_EL18 DOMAIN-CONTAINING PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012630.3|UniProtKB=G3RA70 G3RA70 PTHR12911:SF23 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 nucleus#GO:0005634;membrane#GO:0016020;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000024182.2|UniProtKB=G3S261 G3S261 TMOD4 PTHR10901:SF9 TROPOMODULIN TROPOMODULIN-4 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 multicellular organismal process#GO:0032501;muscle contraction#GO:0006936;developmental process#GO:0032502;system process#GO:0003008;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000009590.3|UniProtKB=A0A2I2Y274 A0A2I2Y274 PTHR11429:SF0 MYELIN BASIC PROTEIN MYELIN BASIC PROTEIN membrane organization#GO:0061024;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cellular component organization#GO:0016043;system development#GO:0048731;myelination#GO:0042552;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 neuron projection#GO:0043005;main axon#GO:0044304;cell body#GO:0044297;neuronal cell body#GO:0043025;myelin sheath#GO:0043209;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424 myelin protein#PC00161;structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000027994.2|UniProtKB=G3SHG7 G3SHG7 PTHR46060:SF3 MARINER MOS1 TRANSPOSASE-LIKE PROTEIN PROTEIN GVQW3 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000016191.3|UniProtKB=G3RT39 G3RT39 ANKAR PTHR46464:SF1 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN AND ARMADILLO REPEAT-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000011442.3|UniProtKB=G3R730 G3R730 KRT76 PTHR45616:SF29 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 2 ORAL structural molecule activity#GO:0005198 cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament organization#GO:0045109;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;skin development#GO:0043588;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;developmental process#GO:0032502;epidermis development#GO:0008544;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 GORGO|Ensembl=ENSGGOG00000012465.3|UniProtKB=G3SBE2 G3SBE2 BTN1A1 PTHR24100:SF139 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000001376.3|UniProtKB=G3QGA9 G3QGA9 NCBP1 PTHR12412:SF3 CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of mRNA metabolic process#GO:1903311;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;mRNA export from nucleus#GO:0006406;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;negative regulation of cellular process#GO:0048523;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;nucleobase-containing compound catabolic process#GO:0034655;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nuclear transport#GO:0051169;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;catabolic process#GO:0009056;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;RNA transport#GO:0050658;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000014596.4|UniProtKB=G3RF81 G3RF81 LOC101139612 PTHR45847:SF3 FATTY ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 1 catalytic activity#GO:0003824;amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;fatty acid catabolic process#GO:0009062 hydrolase#PC00121 Anandamide degradation#P05728>FAAH#P05741 GORGO|Ensembl=ENSGGOG00000023448.2|UniProtKB=G3RYK1 G3RYK1 MC5R PTHR22750:SF5 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 5 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000026366.2|UniProtKB=G3S2F1 G3S2F1 CPE PTHR11532:SF92 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE E exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 Vasopressin synthesis#P04395>Exopeptidase#P04592;CCKR signaling map#P06959>Carboxypeptidase E#P07026 GORGO|Ensembl=ENSGGOG00000039810.1|UniProtKB=A0A2I2Z3F0 A0A2I2Z3F0 HOXB8 PTHR46166:SF2 HOMEOBOX DOMAIN-CONTAINING PROTEIN HOMEOBOX PROTEIN HOX-B8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000012170.3|UniProtKB=G3R900 G3R900 LOC101148582 PTHR13386:SF3 HISTONE PARYLATION FACTOR 1 HISTONE PARYLATION FACTOR 1-LIKE-RELATED protein binding#GO:0005515;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;histone binding#GO:0042393 nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stress#GO:0033554 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000002082.3|UniProtKB=A0A2I2YAA5 A0A2I2YAA5 DNAJC5 PTHR44027:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;primary metabolic process#GO:0044238;protein folding#GO:0006457;regulation of cellular process#GO:0050794;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;regulation of transport#GO:0051049;regulation of localization#GO:0032879;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;presynapse#GO:0098793;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000007215.3|UniProtKB=G3QWA7 G3QWA7 SLC18B1 PTHR23506:SF44 GH10249P MFS-TYPE TRANSPORTER SLC18B1 antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;monoatomic cation transmembrane transporter activity#GO:0008324 cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;presynapse#GO:0098793;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011936.4|UniProtKB=A0A2I2ZG86 A0A2I2ZG86 DPP10 PTHR11731:SF21 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED INACTIVE DIPEPTIDYL PEPTIDASE 10 ion channel regulator activity#GO:0099106;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;peptidase activity#GO:0008233;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;channel regulator activity#GO:0016247 proteolysis#GO:0006508;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;metabolic process#GO:0008152;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of transport#GO:0051049;regulation of localization#GO:0032879;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000016705.3|UniProtKB=A0A2I2ZML3 A0A2I2ZML3 MPO PTHR11475:SF108 OXIDASE/PEROXIDASE MYELOPEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 GORGO|Ensembl=ENSGGOG00000016983.3|UniProtKB=G3RUH1 G3RUH1 SYT7 PTHR10024:SF385 SYNAPTOTAGMIN SYNAPTOTAGMIN-7 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;protein binding#GO:0005515;binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of exocytosis#GO:0017157;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;neurotransmitter secretion#GO:0007269;positive regulation of cellular process#GO:0048522;membrane fusion#GO:0061025;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;export from cell#GO:0140352;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;neurotransmitter transport#GO:0006836;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;cellular process#GO:0009987;organelle organization#GO:0006996;synaptic signaling#GO:0099536;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055 exocytic vesicle#GO:0070382;axon#GO:0030424;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cell junction#GO:0030054;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;presynapse#GO:0098793;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 GORGO|Ensembl=ENSGGOG00000000504.3|UniProtKB=G3QE10 G3QE10 CD1C PTHR16675:SF155 MHC CLASS I-RELATED T-CELL SURFACE GLYCOPROTEIN CD1C binding#GO:0005488;antigen binding#GO:0003823;lipid binding#GO:0008289 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000002974.3|UniProtKB=G3RS33 G3RS33 SCPEP1 PTHR11802:SF3 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE serine-type peptidase activity#GO:0008236;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000036194.1|UniProtKB=A0A2I2ZLE6 A0A2I2ZLE6 COPS8 PTHR13339:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012879.3|UniProtKB=G3RAT7 G3RAT7 IL18R1 PTHR11890:SF6 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR 1 immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to peptide#GO:1901652;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cell surface receptor signaling pathway#GO:0007166;positive regulation of macromolecule metabolic process#GO:0010604;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;adaptive immune response#GO:0002250;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;positive regulation of cellular process#GO:0048522;immune response#GO:0006955 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043974.1|UniProtKB=A0A2I2YMD1 A0A2I2YMD1 FAM133A PTHR31911:SF4 PROTEIN FAM133 PROTEIN FAM133A RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004420.3|UniProtKB=G3QP55 G3QP55 PLXNA2 PTHR22625:SF37 PLEXIN PLEXIN-A2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of nervous system development#GO:0051962;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of axonogenesis#GO:0050770;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;negative regulation of cell adhesion#GO:0007162;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of plasma membrane bounded cell projection organization#GO:0120035 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012362.3|UniProtKB=G3R9I0 G3R9I0 PTHR13339:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009438.3|UniProtKB=G3R1Y8 G3R1Y8 CLK2 PTHR45646:SF6 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000011991.3|UniProtKB=G3S5Q0 G3S5Q0 MYL1 PTHR23048:SF3 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 1_3, SKELETAL MUSCLE ISOFORM microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;structural molecule activity#GO:0005198;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;contractile muscle fiber#GO:0043292 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000000544.3|UniProtKB=G3QE52 G3QE52 ERLEC1 PTHR15414:SF0 OS-9-RELATED ENDOPLASMIC RETICULUM LECTIN 1 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;localization#GO:0051179;cell communication#GO:0007154;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;biological regulation#GO:0065007;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;cellular localization#GO:0051641;response to unfolded protein#GO:0006986;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003104.3|UniProtKB=G3QKS3 G3QKS3 PTPN4 PTHR23280:SF27 4.1 G PROTEIN TYROSINE-PROTEIN PHOSPHATASE cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000003407.3|UniProtKB=G3S081 G3S081 PHKA2 PTHR10749:SF5 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, LIVER ISOFORM serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 GORGO|Ensembl=ENSGGOG00000005096.3|UniProtKB=A0A2I2YTX0 A0A2I2YTX0 SCD5 PTHR11351:SF100 ACYL-COA DESATURASE STEAROYL-COA DESATURASE 5 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506 cellular process#GO:0009987;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000013046.3|UniProtKB=A0A2I2ZPJ5 A0A2I2ZPJ5 CORO2B PTHR10856:SF17 CORONIN CORONIN-2B cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cell-substrate junction organization#GO:0150115;focal adhesion assembly#GO:0048041;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;actin filament-based process#GO:0030029;cell-substrate adhesion#GO:0031589;supramolecular fiber organization#GO:0097435;cell junction assembly#GO:0034329;cell-substrate junction assembly#GO:0007044;cellular component organization#GO:0016043;cell junction organization#GO:0034330;actin cytoskeleton organization#GO:0030036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000015963.3|UniProtKB=A0A2I2YZF6 A0A2I2YZF6 ELF2 PTHR11849:SF10 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000039654.1|UniProtKB=A0A2I2Z3Z9 A0A2I2Z3Z9 PTHR19375:SF564 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515 biosynthetic process#GO:0009058;protein maturation#GO:0051604;vesicle-mediated transport#GO:0016192;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;receptor-mediated endocytosis#GO:0006898;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;metabolic process#GO:0008152;protein-containing complex disassembly#GO:0032984;protein folding#GO:0006457;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein refolding#GO:0042026;localization#GO:0051179;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072;Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 GORGO|Ensembl=ENSGGOG00000013893.3|UniProtKB=G3RDE7 G3RDE7 CTRL PTHR24250:SF66 CHYMOTRYPSIN-RELATED CHYMOTRYPSIN-LIKE PROTEASE CTRL-1 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein modifying enzyme#PC00260;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000025700.2|UniProtKB=G3SAB2 G3SAB2 PPP1R3G PTHR12307:SF7 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3G phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903 regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of polysaccharide metabolic process#GO:0032881;regulation of carbohydrate biosynthetic process#GO:0043255;biological regulation#GO:0065007 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000003003.3|UniProtKB=A0A2I2ZN91 A0A2I2ZN91 PTHR43982:SF1 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;binding#GO:0005488;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;protein-containing complex binding#GO:0044877 negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein catabolic process#GO:0042177;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of metabolic process#GO:0009892;regulation of ERAD pathway#GO:1904292;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of protein catabolic process#GO:0042176;regulation of cellular response to stress#GO:0080135;negative regulation of catabolic process#GO:0009895 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000000199.3|UniProtKB=G3QD86 G3QD86 PTHR15880:SF0 ASPARTATE-RICH PROTEIN 1 ASPARTATE-RICH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000000572.3|UniProtKB=G3QE77 G3QE77 MYH3 PTHR45615:SF6 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-3 cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;actin filament binding#GO:0051015;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008;multicellular organismal process#GO:0032501 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 GORGO|Ensembl=ENSGGOG00000041151.1|UniProtKB=A0A2I2YW54 A0A2I2YW54 PTHR23147:SF110 SERINE/ARGININE RICH SPLICING FACTOR RRM DOMAIN-CONTAINING PROTEIN membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;nuclear speck#GO:0016607;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000023885.2|UniProtKB=G3SG11 G3SG11 LOC101151025 PTHR10570:SF8 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;biological regulation#GO:0065007;T cell differentiation#GO:0030217;hemopoiesis#GO:0030097;immune system process#GO:0002376;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;anatomical structure development#GO:0048856;cell communication#GO:0007154;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;leukocyte activation#GO:0045321;mononuclear cell differentiation#GO:1903131;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD3 gamma#P01317 GORGO|Ensembl=ENSGGOG00000005547.3|UniProtKB=G3QS14 G3QS14 C3H4orf36 PTHR38002:SF1 C4ORF36 ISOFORM 11 CHROMOSOME 8 C4ORF36 HOMOLOG GORGO|Ensembl=ENSGGOG00000015189.3|UniProtKB=G3RGR4 G3RGR4 LRRC73 PTHR24111:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 73 GORGO|Ensembl=ENSGGOG00000026561.2|UniProtKB=A0A2I2ZVQ7 A0A2I2ZVQ7 PTHR11955:SF58 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 5 organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;fatty acid binding#GO:0005504 lipid transport#GO:0006869;macromolecule localization#GO:0033036;localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000016118.3|UniProtKB=G3RJ47 G3RJ47 PCED1A PTHR14469:SF3 SARCOMA ANTIGEN NY-SAR-23 PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1A GORGO|Ensembl=ENSGGOG00000003705.3|UniProtKB=G3RVC1 G3RVC1 LOC101129299 PTHR10510:SF5 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane#GO:0016020;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000023971.2|UniProtKB=G3S763 G3S763 BUB3 PTHR10971:SF31 MRNA EXPORT FACTOR AND BUB3 MITOTIC CHECKPOINT PROTEIN BUB3 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of cell cycle#GO:0045786;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;cellular process#GO:0009987;negative regulation of sister chromatid segregation#GO:0033046;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;negative regulation of chromosome separation#GO:1905819;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036988.1|UniProtKB=A0A2I2ZD48 A0A2I2ZD48 SLC7A6 PTHR11785:SF398 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 2 basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012485.3|UniProtKB=G3R9T4 G3R9T4 GOLM1 PTHR15896:SF8 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED GOLGI MEMBRANE PROTEIN 1 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000898.3|UniProtKB=G3QF23 G3QF23 NT5E PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253 organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 GORGO|Ensembl=ENSGGOG00000004658.3|UniProtKB=G3QPR8 G3QPR8 STRC PTHR23412:SF14 STEREOCILIN RELATED STEREOCILIN-RELATED cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cellular process#GO:0009987 cytoskeleton#GO:0005856;stereocilium#GO:0032420;membraneless organelle#GO:0043228;neuron projection#GO:0043005;intracellular membraneless organelle#GO:0043232;cell surface#GO:0009986;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000006037.3|UniProtKB=A0A2I2Z1B6 A0A2I2Z1B6 PLEKHA2 PTHR14336:SF5 TANDEM PH DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 2 phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000001348.3|UniProtKB=G3S0K7 G3S0K7 HOXD1 PTHR45946:SF1 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-D1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000038153.1|UniProtKB=A0A2I2Z165 A0A2I2Z165 UBE2G2 PTHR24067:SF154 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>Ubc7#P01220 GORGO|Ensembl=ENSGGOG00000012332.3|UniProtKB=G3R9F6 G3R9F6 CDH16 PTHR24027:SF424 CADHERIN-23 CADHERIN-16 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell motility#GO:0048870;cell migration#GO:0016477;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 cell adhesion molecule#PC00069;cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000008413.4|UniProtKB=A0A2I2ZP32 A0A2I2ZP32 ANKS1B PTHR24174:SF3 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1B protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;ephrin receptor signaling pathway#GO:0048013;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;localization#GO:0051179;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 presynapse#GO:0098793;cytosol#GO:0005829;cytoplasm#GO:0005737;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015568.3|UniProtKB=G3RHR0 G3RHR0 CCDC27 PTHR18853:SF9 FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 27 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000039196.1|UniProtKB=A0A2I2YVG8 A0A2I2YVG8 RAP2A PTHR24070:SF221 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2A hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;intracellular signaling cassette#GO:0141124;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cell migration#GO:0030334 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 GORGO|Ensembl=ENSGGOG00000026610.2|UniProtKB=G3S9P7 G3S9P7 PTHR23086:SF107 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PIPK DOMAIN-CONTAINING PROTEIN phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 kinase#PC00137;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000000093.3|UniProtKB=A0A2I2Z672 A0A2I2Z672 PTHR10333:SF41 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 5 histone reader activity#GO:0140566;chromatin binding#GO:0003682;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;binding#GO:0005488;chromatin-protein adaptor activity#GO:0140463 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of apoptotic signaling pathway#GO:2001233;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of signal transduction#GO:0009967;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of programmed cell death#GO:0043068;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008742.3|UniProtKB=A0A2I2Y2J6 A0A2I2Y2J6 PTHR10527:SF22 IMPORTIN BETA IMPORTIN-5 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023834.2|UniProtKB=G3SJC8 G3SJC8 KIAA1191 PTHR28342:SF1 MONOOXYGENASE P33MONOX-RELATED MONOOXYGENASE P33MONOX-RELATED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000014450.3|UniProtKB=G3RF10 G3RF10 DNAH8 PTHR46532:SF11 MALE FERTILITY FACTOR KL5 DYNEIN AXONEMAL HEAVY CHAIN 12 GORGO|Ensembl=ENSGGOG00000024974.2|UniProtKB=A0A2I2ZBF8 A0A2I2ZBF8 LRP11 PTHR46876:SF1 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 GORGO|Ensembl=ENSGGOG00000009651.4|UniProtKB=G3R2J4 G3R2J4 UBR3 PTHR21497:SF39 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR3 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002737.3|UniProtKB=G3QJU1 G3QJU1 TESC PTHR46823:SF2 CALCINEURIN B HOMOLOGOUS PROTEIN 3 CALCINEURIN B HOMOLOGOUS PROTEIN 3 enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;cation binding#GO:0043169;molecular function inhibitor activity#GO:0140678 localization within membrane#GO:0051668;regulation of myeloid cell differentiation#GO:0045637;localization#GO:0051179;regulation of hemopoiesis#GO:1903706;cellular localization#GO:0051641;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;regulation of developmental process#GO:0050793;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;cellular process#GO:0009987;macromolecule localization#GO:0033036;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;regulation of cell adhesion#GO:0030155 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006564.3|UniProtKB=G3QUM3 G3QUM3 SCN11A PTHR10037:SF210 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 11 SUBUNIT ALPHA monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated sodium channel activity#GO:0005248;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272 system process#GO:0003008;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;sensory perception#GO:0007600;nervous system process#GO:0050877;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;action potential#GO:0001508;sodium ion transport#GO:0006814;sensory perception of pain#GO:0019233 transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;axon#GO:0030424;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000016011.3|UniProtKB=G3RIV4 G3RIV4 CRTAC1 PTHR16026:SF5 CARTILAGE ACIDIC PROTEIN 1 CARTILAGE ACIDIC PROTEIN 1 cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell recognition#GO:0008037;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;axon development#GO:0061564;neuron projection development#GO:0031175;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 GORGO|Ensembl=ENSGGOG00000008229.3|UniProtKB=G3QYV0 G3QYV0 SULT6B1 PTHR11783:SF55 SULFOTRANSFERASE SULT SULFOTRANSFERASE 6B1 transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000005769.3|UniProtKB=G3QSK7 G3QSK7 LOC101134435 PTHR15951:SF2 T-CELL RECEPTOR-ASSOCIATED TRANSMEMBRANE ADAPTER 1 T-CELL RECEPTOR-ASSOCIATED TRANSMEMBRANE ADAPTER 1 regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of cellular process#GO:0048523;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;signaling receptor complex#GO:0043235 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008886.3|UniProtKB=G3S3Q9 G3S3Q9 NAPEPLD PTHR15032:SF38 N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D lipase activity#GO:0016298;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000010906.3|UniProtKB=G3R5P9 G3R5P9 CRISP3 PTHR10334:SF577 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN 3 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000011998.3|UniProtKB=G3R8J2 G3R8J2 HIRIP3 PTHR15410:SF2 HIRA-INTERACTING PROTEIN 3 HIRA-INTERACTING PROTEIN 3 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000040509.1|UniProtKB=A0A2I2Y218 A0A2I2Y218 FITM1 PTHR23129:SF3 ACYL-COENZYME A DIPHOSPHATASE FITM2 FAT STORAGE-INDUCING TRANSMEMBRANE PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;chemical homeostasis#GO:0048878;cellular component assembly#GO:0022607;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;lipid storage#GO:0019915;cellular process#GO:0009987;organelle assembly#GO:0070925;lipid droplet organization#GO:0034389;cell differentiation#GO:0030154;homeostatic process#GO:0042592;membraneless organelle assembly#GO:0140694;fat cell differentiation#GO:0045444;cellular component organization#GO:0016043;lipid homeostasis#GO:0055088 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007359.3|UniProtKB=G3SJY2 G3SJY2 ZNF175 PTHR24381:SF405 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 585A RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000023662.2|UniProtKB=G3RPS4 G3RPS4 PTHR45921:SF1 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 3 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000028504.2|UniProtKB=A0A2I2ZNJ4 A0A2I2ZNJ4 PTHR12642:SF2 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000007107.3|UniProtKB=G3QW20 G3QW20 PAPPA PTHR46130:SF2 LAMGL DOMAIN-CONTAINING PROTEIN PAPPALYSIN-1 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000016570.3|UniProtKB=G3RKB5 G3RKB5 DGKK PTHR11255:SF33 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE KAPPA transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid metabolic process#GO:0006638;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;biological regulation#GO:0065007;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000028508.2|UniProtKB=G3RSK3 G3RSK3 PTHR11278:SF3 40S RIBOSOMAL PROTEIN S7 40S RIBOSOMAL PROTEIN S7 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;cytosolic small ribosomal subunit#GO:0022627;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;cytosolic ribosome#GO:0022626;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000042774.1|UniProtKB=G3QFD2 G3QFD2 LOC101135994 PTHR23262:SF201 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-4 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000011928.3|UniProtKB=G3R8D4 G3R8D4 FGG PTHR19143:SF338 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN GAMMA CHAIN primary metabolic process#GO:0044238;hemostasis#GO:0007599;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell activation#GO:0001775;blood coagulation, fibrin clot formation#GO:0072378;protein activation cascade#GO:0072376;cell-substrate adhesion#GO:0031589;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;wound healing#GO:0042060;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;response to wounding#GO:0009611;coagulation#GO:0050817;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;biological regulation#GO:0065007;homotypic cell-cell adhesion#GO:0034109;metabolic process#GO:0008152;platelet aggregation#GO:0070527;platelet activation#GO:0030168;macromolecule metabolic process#GO:0043170;blood coagulation#GO:0007596 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443;Blood coagulation#P00011>Fibrinogen#P00406;Blood coagulation#P00011>Fibrin monomer#P00418 GORGO|Ensembl=ENSGGOG00000041886.1|UniProtKB=A0A2I2ZRE3 A0A2I2ZRE3 CPAMD8 PTHR11412:SF139 MACROGLOBULIN / COMPLEMENT C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN 8 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;visual system development#GO:0150063;animal gross anatomical part developmental process#GO:0160108;sensory organ development#GO:0007423;developmental process#GO:0032502;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system development#GO:0048731 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000011658.3|UniProtKB=G3R7Q4 G3R7Q4 ABCA2 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036;localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000028535.2|UniProtKB=G3S650 G3S650 PTHR13593:SF24 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 GORGO|Ensembl=ENSGGOG00000007187.3|UniProtKB=G3QW87 G3QW87 TBC1D1 PTHR22957:SF204 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 1 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000014662.3|UniProtKB=G3RFD5 G3RFD5 SIAH2 PTHR45877:SF4 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;acyltransferase activity#GO:0016746;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433 GORGO|Ensembl=ENSGGOG00000043244.1|UniProtKB=G3SH74 G3SH74 LOC101135885 PTHR12884:SF25 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009401.3|UniProtKB=G3R1V4 G3R1V4 FBXO44 PTHR12125:SF14 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 6 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004955.3|UniProtKB=G3QQI7 G3QQI7 TMEM150A PTHR21324:SF6 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED TRANSMEMBRANE PROTEIN 150A protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to plasma membrane#GO:0072659;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005954.3|UniProtKB=G3QT25 G3QT25 METTL3 PTHR12829:SF7 N6-ADENOSINE-METHYLTRANSFERASE N(6)-ADENOSINE-METHYLTRANSFERASE CATALYTIC SUBUNIT METTL3 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 mRNA metabolic process#GO:0016071;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;metabolic process#GO:0008152 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000003576.3|UniProtKB=G3QLZ3 G3QLZ3 RET PTHR24416:SF485 TYROSINE-PROTEIN KINASE RECEPTOR PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;signaling receptor complex#GO:0043235;axon#GO:0030424 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001044.3|UniProtKB=G3QFF7 G3QFF7 RNASEH2B PTHR13383:SF11 RIBONUCLEASE H2 SUBUNIT B RIBONUCLEASE H2 SUBUNIT B RNA catabolic process#GO:0006401;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000037542.1|UniProtKB=A0A2I2ZJT5 A0A2I2ZJT5 PTHR23266:SF389 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-70-RELATED binding#GO:0005488;antigen binding#GO:0003823 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000016170.3|UniProtKB=G3RJA1 G3RJA1 PTHR43173:SF28 ABC1 FAMILY PROTEIN AARF DOMAIN CONTAINING KINASE 5 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000024444.2|UniProtKB=G3RUU7 G3RUU7 OVOL2 PTHR10032:SF193 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS TRANSCRIPTION FACTOR OVO-LIKE 2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;epidermis development#GO:0008544;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000000653.3|UniProtKB=G3QEF0 G3QEF0 ZC3HAV1 PTHR45740:SF8 POLY [ADP-RIBOSE] POLYMERASE ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;protein-macromolecule adaptor activity#GO:0030674;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757 regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of immune system process#GO:0002684;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to biotic stimulus#GO:0002833;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of RNA metabolic process#GO:0051252;response to virus#GO:0009615;macromolecule modification#GO:0043412;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of response to external stimulus#GO:0032103;response to chemical#GO:0042221;regulation of intracellular signal transduction#GO:1902531;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;regulation of mRNA catabolic process#GO:0061013;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stress#GO:0080134;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;positive regulation of innate immune response#GO:0045089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;post-translational protein modification#GO:0043687;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;protein metabolic process#GO:0019538;positive regulation of mRNA catabolic process#GO:0061014;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;positive regulation of cell communication#GO:0010647 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000012085.3|UniProtKB=G3R8T0 G3R8T0 ECE1 PTHR11733:SF130 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED ENDOTHELIN-CONVERTING ENZYME 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;peptide hormone processing#GO:0016486;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 GORGO|Ensembl=ENSGGOG00000015927.3|UniProtKB=G3RIM0 G3RIM0 GPRC5A PTHR14511:SF7 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 RETINOIC ACID-INDUCED PROTEIN 3 enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;signaling receptor complex#GO:0043235;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000034948.2|UniProtKB=G3SKH2 G3SKH2 SLFN11 PTHR12155:SF45 SCHLAFEN SCHLAFEN FAMILY MEMBER 11 binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA binding#GO:0000049;RNA binding#GO:0003723 response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to virus#GO:0051607;defense response#GO:0006952;response to external stimulus#GO:0009605;response to virus#GO:0009615 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000010425.3|UniProtKB=G3R4G5 G3R4G5 CSRNP2 PTHR13580:SF6 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN 2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000005328.3|UniProtKB=G3QRG7 G3QRG7 LOC101149133 PTHR23239:SF368 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 14 structural molecule activity#GO:0005198 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelium development#GO:0060429;developmental process#GO:0032502;epidermis development#GO:0008544;morphogenesis of an epithelium#GO:0002009;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000007010.3|UniProtKB=G3QVS8 G3QVS8 TMC8 PTHR23302:SF39 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 8 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000005958.3|UniProtKB=G3QT26 G3QT26 SLC35A1 PTHR10231:SF66 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER CMP-SIALIC ACID TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleotide-sugar transmembrane transport#GO:0015780;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000027944.2|UniProtKB=A0A2I2ZMB1 A0A2I2ZMB1 MOB4 PTHR10772:SF67 10 KDA HEAT SHOCK PROTEIN 10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;small molecule binding#GO:0036094 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000040823.1|UniProtKB=A0A2I2Y7B2 A0A2I2Y7B2 ZNF316 PTHR24408:SF54 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 316 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004746.3|UniProtKB=G3QPZ3 G3QPZ3 PON1 PTHR11799:SF16 PARAOXONASE SERUM PARAOXONASE_ARYLESTERASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;response to toxic substance#GO:0009636;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;response to chemical#GO:0042221 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000011389.3|UniProtKB=G3R6Y2 G3R6Y2 LOC101124172 PTHR26453:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011007.3|UniProtKB=G3R600 G3R600 SCFD1 PTHR11679:SF2 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;syntaxin binding#GO:0019905;SNARE binding#GO:0000149;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;macromolecule localization#GO:0033036;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000011026.3|UniProtKB=G3R610 G3R610 PTHR14047:SF34 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN FAMILY E MEMBER 3-RELATED GORGO|Ensembl=ENSGGOG00000016265.3|UniProtKB=G3RJH6 G3RJH6 NATD1 PTHR31435:SF9 PROTEIN NATD1 PROTEIN NATD1 GORGO|Ensembl=ENSGGOG00000015702.3|UniProtKB=G3RI33 G3RI33 C1orf35 PTHR14580:SF0 MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 FAMILY MEMBER MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 GORGO|Ensembl=ENSGGOG00000000727.4|UniProtKB=G3QEM0 G3QEM0 EIF3H PTHR10410:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT H hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;translation initiation factor activity#GO:0003743;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 eukaryotic translation initiation factor 3 complex#GO:0005852;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000003380.3|UniProtKB=G3RT76 G3RT76 RELB PTHR24169:SF18 NUCLEAR FACTOR NF-KAPPA-B PROTEIN TRANSCRIPTION FACTOR RELB transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of RNA metabolic process#GO:0051254;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;response to other organism#GO:0051707;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;canonical NF-kappaB signal transduction#GO:0007249;regulation of nucleobase-containing compound metabolic process#GO:0019219;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to peptide#GO:1901652;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;intracellular signaling cassette#GO:0141124;defense response to other organism#GO:0098542;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;non-canonical NF-kappaB signal transduction#GO:0038061;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Apoptosis signaling pathway#P00006>NFkappaB#P00297 GORGO|Ensembl=ENSGGOG00000007472.3|UniProtKB=G3QWY6 G3QWY6 WNT5A PTHR12027:SF33 WNT RELATED PROTEIN WNT-5A signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell fate commitment#GO:0045165;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206 GORGO|Ensembl=ENSGGOG00000010754.3|UniProtKB=G3R5B6 G3R5B6 DNAJB9 PTHR44360:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular organelle lumen#GO:0070013 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000040578.1|UniProtKB=G3SCS9 G3SCS9 UBXN10 PTHR23322:SF28 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 10 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008004.3|UniProtKB=G3QY94 G3QY94 APOC3 PTHR14225:SF0 APOLIPOPROTEIN C-III APOLIPOPROTEIN C-III molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;phospholipid binding#GO:0005543;lipid binding#GO:0008289;molecular function inhibitor activity#GO:0140678;lipoprotein particle receptor binding#GO:0070325;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;binding#GO:0005488;signaling receptor binding#GO:0005102 neutral lipid catabolic process#GO:0046461;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;negative regulation of cellular process#GO:0048523;acylglycerol metabolic process#GO:0006639;regulation of catabolic process#GO:0009894;neutral lipid metabolic process#GO:0006638;cholesterol homeostasis#GO:0042632;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;triglyceride homeostasis#GO:0070328;regulation of lipid metabolic process#GO:0019216;negative regulation of catabolic process#GO:0009895;regulation of lipid catabolic process#GO:0050994;negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;acylglycerol catabolic process#GO:0046464;lipid catabolic process#GO:0016042;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;triglyceride catabolic process#GO:0019433;glycerolipid catabolic process#GO:0046503;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;lipid homeostasis#GO:0055088;negative regulation of metabolic process#GO:0009892;glycerolipid metabolic process#GO:0046486 very-low-density lipoprotein particle#GO:0034361;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;lipoprotein particle#GO:1990777;extracellular region#GO:0005576;protein-lipid complex#GO:0032994;extracellular protein-containing complex#GO:0140392;high-density lipoprotein particle#GO:0034364;plasma lipoprotein particle#GO:0034358 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000039010.1|UniProtKB=A0A2I2ZTB4 A0A2I2ZTB4 PTHR24377:SF710 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004416.3|UniProtKB=G3RYV5 G3RYV5 PDE6C PTHR11347:SF23 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA' catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112 sensory perception#GO:0007600;regulation of signaling#GO:0023051;nervous system process#GO:0050877;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;sensory perception of light stimulus#GO:0050953;regulation of cell communication#GO:0010646;visual perception#GO:0007601;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;system process#GO:0003008;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585 hydrolase#PC00121;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000008610.3|UniProtKB=G3QZV1 G3QZV1 RCOR3 PTHR16089:SF13 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 3 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010105.3|UniProtKB=G3R3N2 G3R3N2 ACSS3 PTHR43347:SF5 ACYL-COA SYNTHETASE ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ligase#PC00142;metabolite interconversion enzyme#PC00262 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 GORGO|Ensembl=ENSGGOG00000022018.2|UniProtKB=G3RXH7 G3RXH7 KDELR1 PTHR10585:SF61 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR 1 signal sequence receptor activity#GO:0005048 macromolecule localization#GO:0033036;cellular process#GO:0009987;protein localization to organelle#GO:0033365;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cis-Golgi network#GO:0005801 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000008873.3|UniProtKB=G3R0I4 G3R0I4 PTHR24330:SF4 HOMEOBOX PROTEIN BARH-LIKE BARH-LIKE 2 HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000008579.3|UniProtKB=G3QZR7 G3QZR7 LOC101153433 PTHR26453:SF194 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10P1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006344.3|UniProtKB=A0A2I2ZRW3 A0A2I2ZRW3 CCT8 PTHR11353:SF78 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000015210.3|UniProtKB=G3RGT4 G3RGT4 PTF1A PTHR23349:SF59 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST PANCREAS TRANSCRIPTION FACTOR 1 SUBUNIT ALPHA transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000001723.3|UniProtKB=G3SBA2 G3SBA2 PTHR24050:SF29 PA14 DOMAIN-CONTAINING PROTEIN FIBULIN-1 GORGO|Ensembl=ENSGGOG00000010020.3|UniProtKB=G3R3F9 G3R3F9 EPHA8 PTHR46877:SF7 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 8 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001010.3|UniProtKB=A0A2I2YWS2 A0A2I2YWS2 SEPTIN8 PTHR18884:SF54 SEPTIN SEPTIN-8 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell periphery#GO:0071944;cell cortex#GO:0005938;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000025564.2|UniProtKB=G3SEK2 G3SEK2 RFXAP PTHR15110:SF2 REGULATORY FACTOR X-ASSOCIATED PROTEIN REGULATORY FACTOR X-ASSOCIATED PROTEIN biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005456.3|UniProtKB=G3QRS8 G3QRS8 BEND3 PTHR28665:SF1 BEN DOMAIN-CONTAINING PROTEIN 3 BEN DOMAIN-CONTAINING PROTEIN 3 rDNA binding#GO:0000182;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;nucleolus organization#GO:0007000;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000007774.3|UniProtKB=G3QXR0 G3QXR0 ZNF106 PTHR14435:SF2 ZINC FINGER PROTEIN 106 ZINC FINGER PROTEIN 106 GORGO|Ensembl=ENSGGOG00000004472.3|UniProtKB=G3S7N5 G3S7N5 GABBR1 PTHR10519:SF77 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 GORGO|Ensembl=ENSGGOG00000000191.3|UniProtKB=G3QD78 G3QD78 PSMA4 PTHR11599:SF13 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-4 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000017011.3|UniProtKB=G3SH83 G3SH83 GRIA4 PTHR18966:SF100 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 4 passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;cellular process#GO:0009987 transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;neuron spine#GO:0044309;cell projection#GO:0042995;postsynapse#GO:0098794;dendritic spine#GO:0043197;signaling receptor complex#GO:0043235;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu4#P01015;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 GORGO|Ensembl=ENSGGOG00000002050.3|UniProtKB=G3QI20 G3QI20 UBQLN3 PTHR10677:SF4 UBIQUILIN UBIQUILIN-3 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000395.3|UniProtKB=A0A2I2Z6R6 A0A2I2Z6R6 PTHR12277:SF52 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17A palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824 regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of postsynapse organization#GO:0099175;regulation of synapse structure or activity#GO:0050803;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000009172.3|UniProtKB=G3R1A9 G3R1A9 CADM4 PTHR45889:SF3 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 4 growth factor receptor binding#GO:0070851;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein binding#GO:0005515 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of wound healing#GO:0061041;regulation of intracellular signal transduction#GO:1902531;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;regulation of response to wounding#GO:1903034;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell-cell contact zone#GO:0044291 GORGO|Ensembl=ENSGGOG00000025264.2|UniProtKB=G3RXD2 G3RXD2 PTHR45729:SF9 RABPHILIN, ISOFORM A DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN BETA anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;regulation of exocytosis#GO:0017157;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;export from cell#GO:0140352;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;positive regulation of cellular component organization#GO:0051130;positive regulation of secretion#GO:0051047;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003;regulation of transport#GO:0051049;exocytosis#GO:0006887;regulation of localization#GO:0032879;positive regulation of vesicle fusion#GO:0031340;regulated exocytosis#GO:0045055 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 GORGO|Ensembl=ENSGGOG00000004532.3|UniProtKB=G3QPE9 G3QPE9 BNC2 PTHR15021:SF2 DISCONNECTED-RELATED ZINC FINGER PROTEIN BASONUCLIN-2 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000009850.3|UniProtKB=G3R309 G3R309 SDE2 PTHR12786:SF1 SPLICING FACTOR SF3A-RELATED SPLICING REGULATOR SDE2 nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;RNA binding#GO:0003723 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000008022.3|UniProtKB=G3QYC5 G3QYC5 HYOU1 PTHR45639:SF37 HSC70CB, ISOFORM G-RELATED HYPOXIA UP-REGULATED PROTEIN 1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 negative regulation of programmed cell death#GO:0043069;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of apoptotic process#GO:0042981;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of intracellular signal transduction#GO:1902532;regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 Hsp70 family chaperone#PC00027;chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000000767.3|UniProtKB=G3QEQ7 G3QEQ7 USF2 PTHR46117:SF2 FI24210P1 UPSTREAM STIMULATORY FACTOR 2 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 PDGF signaling pathway#P00047>c-fos#P01145 GORGO|Ensembl=ENSGGOG00000012440.3|UniProtKB=A0A2I2YAR7 A0A2I2YAR7 PTHR11961:SF15 CYTOCHROME C CYTOCHROME C, SOMATIC respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152 organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ATP synthesis#P02721>Cyt C#P02798;Apoptosis signaling pathway#P00006>Cytochrome C#P00322 GORGO|Ensembl=ENSGGOG00000005788.3|UniProtKB=G3QSM6 G3QSM6 ANKLE1 PTHR46427:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1 STRUCTURE-SPECIFIC ENDONUCLEASE ANKLE1 DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520 macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;resolution of meiotic recombination intermediates#GO:0000712;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;homologous recombination#GO:0035825;reproductive process#GO:0022414;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000006236.3|UniProtKB=A0A2I2YQR4 A0A2I2YQR4 OXR1 PTHR23354:SF69 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED OXIDATION RESISTANCE PROTEIN 1 response to stress#GO:0006950;response to stimulus#GO:0050896;response to oxidative stress#GO:0006979 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000016271.3|UniProtKB=G3RJH9 G3RJH9 FOXH1 PTHR47316:SF1 FORKHEAD BOX PROTEIN H1 FORKHEAD BOX PROTEIN H1 winged helix/forkhead transcription factor#PC00246 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 GORGO|Ensembl=ENSGGOG00000011403.3|UniProtKB=G3R6Z4 G3R6Z4 DCLRE1B PTHR23240:SF26 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED 5' EXONUCLEASE APOLLO DNA binding#GO:0003677;hydrolase activity#GO:0016787;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;damaged DNA binding#GO:0003684;DNA exonuclease activity#GO:0004529 cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;double-strand break repair via nonhomologous end joining#GO:0006303 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000001704.3|UniProtKB=G3QH58 G3QH58 TSR1 PTHR12858:SF1 RIBOSOME BIOGENESIS PROTEIN PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;RNA binding#GO:0003723;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000005604.3|UniProtKB=G3QS61 G3QS61 TRIM9 PTHR24099:SF13 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM9 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000028224.2|UniProtKB=G3S4T6 G3S4T6 DDX52 PTHR24031:SF594 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX52-RELATED cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000026605.2|UniProtKB=G3RMJ0 G3RMJ0 ZNF280C PTHR24388:SF62 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 280C sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000000308.3|UniProtKB=G3QDI6 G3QDI6 DGKD PTHR11255:SF30 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE DELTA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;biological regulation#GO:0065007;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;neutral lipid metabolic process#GO:0006638;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Gene=NDUFB2|UniProtKB=Q0MQC8 Q0MQC8 NDUFB2 PTHR15223:SF1 NADH-UBIQUINONE OXIDOREDUCTASE AGGG SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006401.3|UniProtKB=G3QU66 G3QU66 CLEC5A PTHR47536:SF1 C-TYPE LECTIN DOMAIN FAMILY 5 MEMBER A C-TYPE LECTIN DOMAIN FAMILY 5 MEMBER A binding#GO:0005488;protein binding#GO:0005515;virus receptor activity#GO:0001618 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 GORGO|Ensembl=ENSGGOG00000002442.3|UniProtKB=G3QJ26 G3QJ26 CAMSAP3 PTHR21595:SF2 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 3 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein depolymerization#GO:1901880;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;cellular component organization#GO:0016043;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;cytoplasmic microtubule organization#GO:0031122;regulation of microtubule-based process#GO:0032886;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435 microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 GORGO|Ensembl=ENSGGOG00000014309.3|UniProtKB=A0A2I2Z667 A0A2I2Z667 ERBB4 PTHR24416:SF90 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;signaling receptor binding#GO:0005102;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;growth factor receptor binding#GO:0070851;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;positive regulation of cell population proliferation#GO:0008284;negative regulation of biological process#GO:0048519 signaling receptor complex#GO:0043235;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>EGFR#P00466;Alzheimer disease-presenilin pathway#P00004>Erb-B4 transmembrane fragment#P00113;Alzheimer disease-presenilin pathway#P00004>Erb-B4 C-terminal fragment#P00163;Alzheimer disease-presenilin pathway#P00004>Erb-B4#P00128;Alzheimer disease-presenilin pathway#P00004>Erb-B4 N-terminal fragment#P00148;EGF receptor signaling pathway#P00018>EGFR#P00542 GORGO|Ensembl=ENSGGOG00000003026.3|UniProtKB=G3S2K6 G3S2K6 SUSD4 PTHR47007:SF1 SUSHI DOMAIN-CONTAINING PROTEIN 4 SUSHI DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000037611.1|UniProtKB=A0A2I2Z5N0 A0A2I2Z5N0 PTHR11524:SF12 60S RIBOSOMAL PROTEIN L7 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025058.2|UniProtKB=G3QZN2 G3QZN2 CEP19 PTHR31539:SF1 CENTROSOMAL PROTEIN OF 19K CEP19 CENTROSOMAL PROTEIN OF 19 KDA cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;Golgi vesicle transport#GO:0048193;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;vesicle-mediated transport to the plasma membrane#GO:0098876;microtubule anchoring#GO:0034453;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;Golgi to plasma membrane transport#GO:0006893;localization within membrane#GO:0051668;organelle assembly#GO:0070925;trans-Golgi to periciliary membrane compartment transport#GO:0097712;cilium organization#GO:0044782;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179 spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spindle pole#GO:0000922;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005987.3|UniProtKB=G3QT47 G3QT47 ICAM4 PTHR13771:SF8 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 4 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cell adhesion mediated by integrin#GO:0033627;cell adhesion#GO:0007155;leukocyte cell-cell adhesion#GO:0007159;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000012842.3|UniProtKB=G3RAQ3 G3RAQ3 PLK1 PTHR24345:SF93 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cellular process#GO:0009987;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049 microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000015488.3|UniProtKB=G3RHI8 G3RHI8 IRS2 PTHR10614:SF7 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 2 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971 cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;response to endogenous stimulus#GO:0009719;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759;Interleukin signaling pathway#P00036>IRS1/2#P00980;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899 GORGO|Ensembl=ENSGGOG00000014961.3|UniProtKB=G3RG60 G3RG60 POLDIP3 PTHR19965:SF96 RNA AND EXPORT FACTOR BINDING PROTEIN POLYMERASE DELTA-INTERACTING PROTEIN 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;nuclear transport#GO:0051169;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007689.3|UniProtKB=A0A2I2Z864 A0A2I2Z864 ULK2 PTHR24348:SF18 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cell size#GO:0008361;developmental growth involved in morphogenesis#GO:0060560;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component size#GO:0032535;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;regulation of axonogenesis#GO:0050770;cell growth#GO:0016049;plasma membrane bounded cell projection morphogenesis#GO:0120039;metabolic process#GO:0008152;regulation of multicellular organismal process#GO:0051239;regulation of cell growth#GO:0001558;cellular component assembly#GO:0022607;autophagy#GO:0006914;response to stress#GO:0006950;system development#GO:0048731;vacuole organization#GO:0007033;regulation of nervous system development#GO:0051960;organelle assembly#GO:0070925;regulation of developmental process#GO:0050793;catabolic process#GO:0009056;regulation of growth#GO:0040008;response to starvation#GO:0042594;negative regulation of cellular component organization#GO:0051129;cellular developmental process#GO:0048869;developmental process#GO:0032502;autophagy of mitochondrion#GO:0000422;negative regulation of cell growth#GO:0030308;plasma membrane bounded cell projection organization#GO:0120036;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;reticulophagy#GO:0061709;axon development#GO:0061564;regulation of biological quality#GO:0065008;neuron projection extension#GO:1990138;neuron development#GO:0048666;axonogenesis#GO:0007409;process utilizing autophagic mechanism#GO:0061919;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;neuron differentiation#GO:0030182;growth#GO:0040007;regulation of anatomical structure size#GO:0090066;axon extension#GO:0048675;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;organelle organization#GO:0006996;anatomical structure development#GO:0048856;piecemeal microautophagy of the nucleus#GO:0034727;developmental cell growth#GO:0048588;regulation of cellular process#GO:0050794;negative regulation of multicellular organismal process#GO:0051241;regulation of neurogenesis#GO:0050767;neurogenesis#GO:0022008;regulation of catabolic process#GO:0009894;regulation of plasma membrane bounded cell projection organization#GO:0120035;mitophagy#GO:0000423;developmental growth#GO:0048589;regulation of cell differentiation#GO:0045595;neuron projection morphogenesis#GO:0048812;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell development#GO:0060284;regulation of metabolic process#GO:0019222 autophagosome#GO:0005776;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010575.3|UniProtKB=G3R4U7 G3R4U7 SDSL PTHR48078:SF16 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED SERINE DEHYDRATASE-LIKE catalytic activity#GO:0003824;lyase activity#GO:0016829 proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;branched-chain amino acid biosynthetic process#GO:0009082;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 lyase#PC00144;dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000027824.2|UniProtKB=G3RJC2 G3RJC2 PTHR15566:SF10 POM121-LIKE UPF0607 PROTEIN ENSP00000332738-RELATED GORGO|Ensembl=ENSGGOG00000011907.4|UniProtKB=G3R8B5 G3R8B5 DNAJC1 PTHR44653:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000042739.1|UniProtKB=A0A2I2YZD1 A0A2I2YZD1 KCNK12 PTHR11003:SF11 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 12 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001536.3|UniProtKB=A0A2I2ZYR7 A0A2I2ZYR7 GINS4 PTHR21206:SF0 SLD5 PROTEIN DNA REPLICATION COMPLEX GINS PROTEIN SLD5 double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;DNA replication preinitiation complex#GO:0031261;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-DNA complex#GO:0032993;organelle#GO:0043226;nucleoplasm#GO:0005654;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000009970.3|UniProtKB=A0A2I2ZX04 A0A2I2ZX04 ABHD16A PTHR12277:SF54 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLSERINE LIPASE ABHD16A hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;catalytic activity#GO:0003824 glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;neutral lipid metabolic process#GO:0006638;glycerophospholipid catabolic process#GO:0046475;acylglycerol catabolic process#GO:0046464;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;glycerophospholipid metabolic process#GO:0006650 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000039948.1|UniProtKB=A0A2I2ZGV2 A0A2I2ZGV2 CFAP47 PTHR45912:SF4 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 47 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 47 cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;sperm motility#GO:0097722;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000007137.3|UniProtKB=G3SGZ4 G3SGZ4 RBBP6 PTHR15439:SF0 RETINOBLASTOMA-BINDING PROTEIN 6 E3 UBIQUITIN-PROTEIN LIGASE RBBP6 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000015837.3|UniProtKB=G3S9F3 G3S9F3 GTF3C5 PTHR13230:SF5 GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5 macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA transcription#GO:0009303;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383 transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127;protein-containing complex#GO:0032991 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000042435.1|UniProtKB=G3S801 G3S801 PTHR14199:SF44 NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 6-LIKE PROTEIN OLDUVAI DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000004257.3|UniProtKB=G3QNQ4 G3QNQ4 ADAP2 PTHR46021:SF6 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 2 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;phosphatidylinositol phosphate binding#GO:1901981;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 circulatory system development#GO:0072359;heart development#GO:0007507;multicellular organismal process#GO:0032501;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000007051.3|UniProtKB=G3S1N6 G3S1N6 PTHR24028:SF305 CADHERIN-87A PROTOCADHERIN ALPHA-6-RELATED cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000000788.3|UniProtKB=G3QES8 G3QES8 BEND6 PTHR35346:SF1 BEN DOMAIN-CONTAINING PROTEIN 6 BEN DOMAIN-CONTAINING PROTEIN 6 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;regulation of neuron differentiation#GO:0045664;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;positive regulation of cell differentiation#GO:0045597;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;negative regulation of Notch signaling pathway#GO:0045746;positive regulation of developmental process#GO:0051094 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000016677.3|UniProtKB=G3S0M6 G3S0M6 GLYATL3 PTHR15298:SF6 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 3 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000003438.3|UniProtKB=G3QLM0 G3QLM0 PTHR13276:SF0 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;post-Golgi vesicle-mediated transport#GO:0006892 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytosol#GO:0005829 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000002608.3|UniProtKB=G3QJH7 G3QJH7 UPF1 PTHR10887:SF364 DNA2/NAM7 HELICASE FAMILY REGULATOR OF NONSENSE TRANSCRIPTS 1 isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000001810.3|UniProtKB=G3QHF5 G3QHF5 PCDH19 PTHR24028:SF40 CADHERIN-87A PROTOCADHERIN-19 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000011718.3|UniProtKB=G3R7S9 G3R7S9 PTHR24070:SF373 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 PDGF signaling pathway#P00047>Ras#P01154 GORGO|Ensembl=ENSGGOG00000006982.3|UniProtKB=G3QVQ6 G3QVQ6 RFX6 PTHR12619:SF28 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;chemical homeostasis#GO:0048878;glucose homeostasis#GO:0042593;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;carbohydrate homeostasis#GO:0033500;pancreas development#GO:0031016;homeostatic process#GO:0042592;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000013848.3|UniProtKB=G3RSH5 G3RSH5 HSPA4L PTHR45639:SF5 HSC70CB, ISOFORM G-RELATED HEAT SHOCK 70 KDA PROTEIN 4L enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072;Hsp70 family chaperone#PC00027 GORGO|Ensembl=ENSGGOG00000000014.3|UniProtKB=G3QCR9 G3QCR9 RMND5B PTHR12170:SF6 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5B catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000011243.3|UniProtKB=A0A2I2YXH5 A0A2I2YXH5 SMAP1 PTHR45705:SF8 FI20236P1 STROMAL MEMBRANE-ASSOCIATED PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008876.3|UniProtKB=G3R0J0 G3R0J0 MOGAT1 PTHR12317:SF26 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid metabolic process#GO:0006638;primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000005052.3|UniProtKB=G3QQS4 G3QQS4 CSF3 PTHR10511:SF2 GRANULOCYTE COLONY-STIMULATING FACTOR GRANULOCYTE COLONY-STIMULATING FACTOR protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018 anatomical structure development#GO:0048856;regulation of hemopoiesis#GO:1903706;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of developmental process#GO:0050793;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;hemopoiesis#GO:0030097;biological regulation#GO:0065007;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;positive regulation of myeloid cell differentiation#GO:0045639;response to peptide#GO:1901652;regulation of myeloid cell differentiation#GO:0045637;myeloid cell differentiation#GO:0030099;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;leukocyte differentiation#GO:0002521;regulation of multicellular organismal development#GO:2000026;mononuclear cell differentiation#GO:1903131;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell differentiation#GO:0045597;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000009605.3|UniProtKB=A0A2I2Y6T2 A0A2I2Y6T2 CDC42BPA PTHR22988:SF31 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE MRCK ALPHA protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000014930.3|UniProtKB=G3RG35 G3RG35 UTP14A PTHR14150:SF14 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG A enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000027326.2|UniProtKB=G3RWF9 G3RWF9 FOXD3 PTHR11829:SF405 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000014885.3|UniProtKB=G3RFZ5 G3RFZ5 SCAF11 PTHR47048:SF1 PROTEIN SCAF11 PROTEIN SCAF11 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 GORGO|Ensembl=ENSGGOG00000013431.3|UniProtKB=G3SK12 G3SK12 PTH1R PTHR45620:SF27 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE_PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;identical protein binding#GO:0042802;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;binding#GO:0005488 signal transduction#GO:0007165;cellular process#GO:0009987;renal system process#GO:0003014;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;chemical homeostasis#GO:0048878;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;system process#GO:0003008;cellular homeostasis#GO:0019725;renal absorption#GO:0070293;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;signaling#GO:0023052;homeostatic process#GO:0042592;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;inorganic ion homeostasis#GO:0098771;G protein-coupled receptor signaling pathway#GO:0007186;calcium ion homeostasis#GO:0055074;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000527.3|UniProtKB=G3QE34 G3QE34 FOS PTHR23351:SF4 FOS TRANSCRIPTION FACTOR-RELATED PROTEIN C-FOS sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>c-fos#G06680;Apoptosis signaling pathway#P00006>Fos#P00317;B cell activation#P00010>fos#P00380;Interleukin signaling pathway#P00036>c-fos#P00967;Gonadotropin-releasing hormone receptor pathway#P06664>c-fos#G06894;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>c-fos#P00884;CCKR signaling map#P06959>FOS#G06973;CCKR signaling map#P06959>FOS#G07266;T cell activation#P00053>fos#P01309;CCKR signaling map#P06959>FOS#P07035;Gonadotropin-releasing hormone receptor pathway#P06664>FOS#P06709;Angiogenesis#P00005>c-Fos#P00235;Huntington disease#P00029>Fos protein#P00801;PDGF signaling pathway#P00047>c-fos#P01145 GORGO|Ensembl=ENSGGOG00000004234.3|UniProtKB=G3QNN6 G3QNN6 ZNF613 PTHR24377:SF900 IP01015P-RELATED ZINC FINGER PROTEIN 577 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005947.3|UniProtKB=G3QT16 G3QT16 LOC101135339 PTHR23430:SF37 HISTONE H2A CORE HISTONE MACRO-H2A.2 structural molecule activity#GO:0005198 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase I#GO:0006356;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010224.3|UniProtKB=G3R3Y6 G3R3Y6 CAMLG PTHR15026:SF0 CALCIUM-SIGNAL MODULATING CYCLOPHILIN LIGAND CAML GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR CAMLG intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000015960.3|UniProtKB=G3RIQ2 G3RIQ2 PRELP PTHR45712:SF8 AGAP008170-PA PROLARGIN heparin binding#GO:0008201;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002585.3|UniProtKB=G3QJF3 G3QJF3 WIF1 PTHR14949:SF32 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 WNT INHIBITORY FACTOR 1 signaling receptor binding#GO:0005102;receptor serine/threonine kinase binding#GO:0033612;binding#GO:0005488;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000011309.3|UniProtKB=G3S1Q3 G3S1Q3 PHOX2A PTHR24329:SF303 HOMEOBOX PROTEIN ARISTALESS PAIRED MESODERM HOMEOBOX PROTEIN 2A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;cell development#GO:0048468;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000004815.3|UniProtKB=G3QQ58 G3QQ58 ZBTB46 PTHR24414:SF63 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 46 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000017176.3|UniProtKB=G3RLV2 G3RLV2 PTHR46983:SF4 CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000000220.3|UniProtKB=G3RR89 G3RR89 IRAK1 PTHR24419:SF1 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1 protein serine/threonine kinase activity#GO:0004674;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096 cell cycle#GO:0007049;innate immune response-activating signaling pathway#GO:0002758;positive regulation of signal transduction#GO:0009967;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cytokine-mediated signaling pathway#GO:0019221;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;defense response to other organism#GO:0098542;cellular response to lipid#GO:0071396;regulation of response to external stimulus#GO:0032101;immune response-activating signaling pathway#GO:0002757;response to lipopolysaccharide#GO:0032496;mitotic cell cycle#GO:0000278;positive regulation of cell communication#GO:0010647;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to bacterium#GO:0009617;lipopolysaccharide-mediated signaling pathway#GO:0031663;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;toll-like receptor 4 signaling pathway#GO:0034142;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to lipid#GO:0033993;cell surface receptor signaling pathway#GO:0007166;positive regulation of response to external stimulus#GO:0032103;positive regulation of canonical NF-kappaB signal transduction#GO:0043123 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>IRAK1#P01343 GORGO|Ensembl=ENSGGOG00000037923.1|UniProtKB=A0A2I2Y6N4 A0A2I2Y6N4 PAFAH1B2 PTHR11852:SF1 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT ALPHA2 carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953 catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003808.3|UniProtKB=G3QML0 G3QML0 DLEC1 PTHR46348:SF1 DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1 DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1 binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014302.3|UniProtKB=G3REG3 G3REG3 NEU4 PTHR10628:SF22 SIALIDASE SIALIDASE-4 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate catabolic process#GO:0016052;ceramide metabolic process#GO:0006672;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;glycolipid metabolic process#GO:0006664;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;oligosaccharide metabolic process#GO:0009311;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;lysosome#GO:0005764 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000004020.3|UniProtKB=G3QN39 G3QN39 MAB21L4 PTHR10656:SF7 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 4 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;cellular response to nitrogen compound#GO:1901699;negative regulation of DNA metabolic process#GO:0051053;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;response to nitrogen compound#GO:1901698;positive regulation of cytokine production#GO:0001819;regulation of response to biotic stimulus#GO:0002831;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of response to external stimulus#GO:0032103;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;regulation of DNA metabolic process#GO:0051052;regulation of double-strand break repair via homologous recombination#GO:0010569;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of double-strand break repair#GO:2000779;positive regulation of type I interferon production#GO:0032481;negative regulation of DNA recombination#GO:0045910;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;chromosome#GO:0005694;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 transferase#PC00220;nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000012857.4|UniProtKB=G3RAR2 G3RAR2 TSC22D1 PTHR46745:SF1 TSC22 DOMAIN FAMILY PROTEIN 1 TSC22 DOMAIN FAMILY PROTEIN 1 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;positive regulation of cell population proliferation#GO:0008284;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003990.3|UniProtKB=A0A2I2YUR7 A0A2I2YUR7 TMEM108 PTHR28673:SF1 TRANSMEMBRANE PROTEIN 108 TRANSMEMBRANE PROTEIN 108 organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;neuron differentiation#GO:0030182;cell growth#GO:0016049;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;postsynaptic density organization#GO:0097106;retrograde axonal transport#GO:0008090;generation of neurons#GO:0048699;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;neuron development#GO:0048666;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;axo-dendritic transport#GO:0008088;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;developmental growth#GO:0048589;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;neurogenesis#GO:0022008;microtubule-based movement#GO:0007018;cell junction organization#GO:0034330;developmental cell growth#GO:0048588;postsynapse organization#GO:0099173;axonal transport#GO:0098930;synapse organization#GO:0050808;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;postsynaptic specialization organization#GO:0099084 vesicle membrane#GO:0012506;membrane#GO:0016020;neuron projection#GO:0043005;postsynaptic specialization#GO:0099572;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;neuron to neuron synapse#GO:0098984;cytoplasm#GO:0005737;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;vesicle#GO:0031982;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;axon#GO:0030424;endosome#GO:0005768;endosome membrane#GO:0010008;postsynaptic density#GO:0014069;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003654.3|UniProtKB=G3QM70 G3QM70 ARHGAP17 PTHR14130:SF3 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 17 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000006757.3|UniProtKB=G3QV46 G3QV46 SNAPC3 PTHR13421:SF16 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;core promoter sequence-specific DNA binding#GO:0001046;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase III#GO:0042796;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA transcription#GO:0009301;transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000005735.3|UniProtKB=G3QSI4 G3QSI4 RC3H1 PTHR13139:SF6 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN ROQUIN-1 acyltransferase activity#GO:0016746;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;RNA binding#GO:0003723;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;protein ubiquitination#GO:0016567;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000005572.3|UniProtKB=A0A2I2YAL9 A0A2I2YAL9 LYRM9 PTHR47061:SF1 LYR MOTIF-CONTAINING PROTEIN 9 LYR MOTIF-CONTAINING PROTEIN 9 GORGO|Ensembl=ENSGGOG00000013181.3|UniProtKB=A0A2I2YMI7 A0A2I2YMI7 CLMP PTHR44783:SF1 CXADR-LIKE MEMBRANE PROTEIN CXADR-LIKE MEMBRANE PROTEIN GORGO|Ensembl=ENSGGOG00000004421.3|UniProtKB=G3QP49 G3QP49 SSU72 PTHR20383:SF11 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 mRNA processing#GO:0006397;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;transcription by RNA polymerase II#GO:0006366;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000015678.3|UniProtKB=G3RI18 G3RI18 ABCB7 PTHR24221:SF402 ATP-BINDING CASSETTE SUB-FAMILY B IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000010024.3|UniProtKB=G3R3F8 G3R3F8 MCPH1 PTHR14625:SF3 MICROCEPHALIN MICROCEPHALIN mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000005109.3|UniProtKB=G3QQY3 G3QQY3 ANXA6 PTHR10502:SF19 ANNEXIN ANNEXIN A6 phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;ion binding#GO:0043167;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;anion binding#GO:0043168;binding#GO:0005488 monoatomic ion homeostasis#GO:0050801;signal transduction#GO:0007165;cellular process#GO:0009987;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;response to stimulus#GO:0050896;signaling#GO:0023052;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;biological regulation#GO:0065007;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;establishment of localization#GO:0051234;apoptotic signaling pathway#GO:0097190;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;mitochondrial calcium ion homeostasis#GO:0051560;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;metal ion transport#GO:0030001;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000006787.3|UniProtKB=G3QV84 G3QV84 IPO9 PTHR10997:SF9 IMPORTIN-7, 8, 11 IMPORTIN-9 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;organelle envelope#GO:0031967 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010350.3|UniProtKB=A0A2I2ZAM6 A0A2I2ZAM6 LDHA PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000014401.3|UniProtKB=G3REQ1 G3REQ1 FAM180B PTHR34034:SF1 PROTEIN FAM180A-RELATED PROTEIN FAM180B GORGO|Ensembl=ENSGGOG00000011599.3|UniProtKB=G3QF51 G3QF51 ACTA1 PTHR11937:SF193 ACTIN ACTIN, ALPHA SKELETAL MUSCLE structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;cell development#GO:0048468;actomyosin structure organization#GO:0031032;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001 actin filament bundle#GO:0032432;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;stress fiber#GO:0001725;actin filament#GO:0005884;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;actomyosin#GO:0042641 actin and actin related protein#PC00039 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858 GORGO|Ensembl=ENSGGOG00000001265.4|UniProtKB=G3QG05 G3QG05 SLC9C1 PTHR10110:SF87 SODIUM/HYDROGEN EXCHANGER SOLUTE CARRIER FAMILY 9 MEMBER C1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000038108.1|UniProtKB=A0A2I2ZQJ9 A0A2I2ZQJ9 PTHR24028:SF41 CADHERIN-87A PROTOCADHERIN-17 nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;system development#GO:0048731;anatomical structure development#GO:0048856;synapse organization#GO:0050808;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000000742.4|UniProtKB=G3QEN4 G3QEN4 PTHR10075:SF108 BASIGIN RELATED NEUROPLASTIN cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000017134.3|UniProtKB=G3SDP4 G3SDP4 ARIH2 PTHR11685:SF210 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH2 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000036384.1|UniProtKB=A0A2I2YVN8 A0A2I2YVN8 PTHR33426:SF27 C2H2-TYPE DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 671 GORGO|Ensembl=ENSGGOG00000012089.3|UniProtKB=G3R8S3 G3R8S3 PTHR20437:SF2 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 13/17 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13C positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte proliferation#GO:0050671;regulation of T cell proliferation#GO:0042129;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of B cell proliferation#GO:0030890;positive regulation of cell adhesion#GO:0045785;positive regulation of leukocyte proliferation#GO:0070665;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of cellular process#GO:0048522;immune system process#GO:0002376;positive regulation of T cell proliferation#GO:0042102;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of B cell proliferation#GO:0030888;positive regulation of leukocyte activation#GO:0002696;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;regulation of B cell activation#GO:0050864;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of biological process#GO:0048518 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000024793.2|UniProtKB=G3S087 G3S087 PTHR24253:SF132 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE-LIKE PROTEIN 51 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006438.3|UniProtKB=A0A2I2ZB18 A0A2I2ZB18 PTHR22792:SF159 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 7 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014222.3|UniProtKB=G3RE96 G3RE96 GOT1L1 PTHR11879:SF6 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC 2 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 GORGO|Ensembl=ENSGGOG00000007931.3|UniProtKB=G3QY32 G3QY32 DRD5 PTHR24248:SF136 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(1B) DOPAMINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;neurotransmitter receptor activity#GO:0030594 G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;adrenergic receptor signaling pathway#GO:0071875 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948 GORGO|Ensembl=ENSGGOG00000001069.3|UniProtKB=G3QFI1 G3QFI1 ADGB PTHR46298:SF1 ANDROGLOBIN ANDROGLOBIN plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000023004.2|UniProtKB=G3SHH3 G3SHH3 LOC129530050 PTHR45635:SF13 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 3 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000008715.3|UniProtKB=G3R046 G3R046 POU2F3 PTHR11636:SF81 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 3 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000010215.3|UniProtKB=A0A2I2ZIH3 A0A2I2ZIH3 STOM PTHR10264:SF115 BAND 7 PROTEIN-RELATED STOMATIN ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000001221.3|UniProtKB=G3QFX0 G3QFX0 CAMK1G PTHR24347:SF116 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;calmodulin binding#GO:0005516;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000007960.3|UniProtKB=G3QY63 G3QY63 PMS2 PTHR10073:SF58 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2 catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536 macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;developmental process#GO:0032502;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;system development#GO:0048731;anatomical structure development#GO:0048856;immune system development#GO:0002520;cellular response to stress#GO:0033554;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;somatic diversification of immune receptors#GO:0002200;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000015493.3|UniProtKB=G3RHJ5 G3RHJ5 CDC6 PTHR10763:SF26 CELL DIVISION CONTROL PROTEIN 6-RELATED DNA REPLICATION FACTOR CDC6 sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;binding#GO:0005488 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 replication origin binding protein#PC00199 GORGO|Ensembl=ENSGGOG00000015304.3|UniProtKB=G3RH17 G3RH17 DGLUCY PTHR32022:SF10 D-GLUTAMATE CYCLASE, MITOCHONDRIAL D-GLUTAMATE CYCLASE, MITOCHONDRIAL cyclase activity#GO:0009975;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 lyase#PC00144;cyclase#PC00079 GORGO|Ensembl=ENSGGOG00000008135.3|UniProtKB=G3QYM8 G3QYM8 PTHR24092:SF50 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IIB-RELATED intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657 phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;vesicle-mediated transport#GO:0016192;lipid transport#GO:0006869;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;Golgi vesicle transport#GO:0048193;lipid translocation#GO:0034204;endocytosis#GO:0006897;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876 Golgi apparatus#GO:0005794;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000006472.3|UniProtKB=A0A2I2YPI1 A0A2I2YPI1 ASB8 PTHR24134:SF9 ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043 ANKYRIN REPEAT AND SOCS BOX PROTEIN 8 GORGO|Ensembl=ENSGGOG00000016678.3|UniProtKB=G3RKK3 G3RKK3 MINDY4B PTHR12473:SF18 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4B peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824 GORGO|Ensembl=ENSGGOG00000004154.3|UniProtKB=G3QNH5 G3QNH5 PTHR19229:SF269 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 10 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000025060.2|UniProtKB=G3SFH5 G3SFH5 GNPNAT1 PTHR13355:SF11 GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE glucosamine 6-phosphate N-acetyltransferase activity#GO:0004343;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000027339.2|UniProtKB=G3SFP0 G3SFP0 PTHR21454:SF23 DPH3 HOMOLOG-RELATED DPH3 HOMOLOG B-RELATED transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;iron ion binding#GO:0005506;metal ion binding#GO:0046872 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;metabolic process#GO:0008152;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000040762.1|UniProtKB=A0A2I2YG17 A0A2I2YG17 CR1 PTHR19325:SF545 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT RECEPTOR TYPE 1 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;T cell mediated immunity#GO:0002456;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;regulation of immune effector process#GO:0002697;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;negative regulation of response to stimulus#GO:0048585;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;adaptive immune response#GO:0002250;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 complement component#PC00078;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010059.3|UniProtKB=G3S7I3 G3S7I3 PTHR11972:SF58 NADPH OXIDASE NADPH OXIDASE 5 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 defense response#GO:0006952;response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801;cellular process#GO:0009987;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;catalytic complex#GO:1902494 oxidase#PC00175;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000592.3|UniProtKB=G3QE93 G3QE93 MEST PTHR43139:SF43 SI:DKEY-122A22.2 MESODERM-SPECIFIC TRANSCRIPT HOMOLOG PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023762.2|UniProtKB=G3SA58 G3SA58 AJM1 PTHR21517:SF3 APICAL JUNCTION COMPONENT 1 HOMOLOG APICAL JUNCTION COMPONENT 1 HOMOLOG cellular component organization#GO:0016043;cell-cell junction organization#GO:0045216;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000023562.2|UniProtKB=G3RUD3 G3RUD3 ZNF75A PTHR24381:SF268 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 75A transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009065.3|UniProtKB=G3S7E1 G3S7E1 ANKRD52 PTHR24178:SF21 MOLTING PROTEIN MLT-4 ANKYRIN REPEAT AND SOCS BOX PROTEIN 3 macromolecule localization#GO:0033036;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;protein localization to cilium#GO:0061512 cilium#GO:0005929;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000042521.1|UniProtKB=A0A2I2Z1Q5 A0A2I2Z1Q5 SH3GLB1 PTHR14167:SF52 SH3 DOMAIN-CONTAINING ENDOPHILIN-B1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000154.3|UniProtKB=G3QD49 G3QD49 SH3RF1 PTHR14167:SF44 SH3 DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE SH3RF1 molecular adaptor activity#GO:0060090;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;protein-macromolecule adaptor activity#GO:0030674;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neuron migration#GO:0001764;neurogenesis#GO:0022008;positive regulation of signal transduction#GO:0009967;regulation of cellular process#GO:0050794;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;anatomical structure development#GO:0048856;system development#GO:0048731;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;regulation of JNK cascade#GO:0046328;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of JNK cascade#GO:0046330;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;positive regulation of signaling#GO:0023056 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016578.3|UniProtKB=G3RKA8 G3RKA8 FHIP1A PTHR21705:SF6 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 1A GORGO|Ensembl=ENSGGOG00000004473.3|UniProtKB=G3QP99 G3QP99 RASGRP4 PTHR23113:SF157 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 4 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;Ras protein signal transduction#GO:0007265;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of immune effector process#GO:0002697;cell communication#GO:0007154;positive regulation of lymphocyte mediated immunity#GO:0002708;intracellular signal transduction#GO:0035556;regulation of natural killer cell mediated immunity#GO:0002715;cellular response to stimulus#GO:0051716;regulation of leukocyte mediated immunity#GO:0002703;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of response to biotic stimulus#GO:0002831;positive regulation of response to external stimulus#GO:0032103;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of response to external stimulus#GO:0032101;intracellular signaling cassette#GO:0141124;regulation of lymphocyte mediated immunity#GO:0002706;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 GORGO|Ensembl=ENSGGOG00000008893.3|UniProtKB=G3RQK0 G3RQK0 DNAH7 PTHR46961:SF8 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN HEAVY CHAIN DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000015332.3|UniProtKB=G3RH46 G3RH46 TYROBP PTHR17554:SF2 TYRO PROTEIN TYROSINE KINASE-BINDING PROTEIN TYRO PROTEIN TYROSINE KINASE-BINDING PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of lymphocyte activation#GO:0051249;positive regulation of cellular component organization#GO:0051130;cell activation involved in immune response#GO:0002263;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of B cell activation#GO:0050864;response to stress#GO:0006950;regulation of multicellular organismal process#GO:0051239;microglial cell activation#GO:0001774;myeloid leukocyte activation#GO:0002274;immune effector process#GO:0002252;positive regulation of leukocyte activation#GO:0002696;regulation of leukocyte mediated immunity#GO:0002703;leukocyte activation#GO:0045321;inflammatory response#GO:0006954;cell activation#GO:0001775;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of gene expression#GO:0010468;macrophage activation#GO:0042116;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;negative regulation of biological process#GO:0048519;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell killing#GO:0031341;immune system process#GO:0002376;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of immune system process#GO:0002684;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;leukocyte activation involved in immune response#GO:0002366;regulation of B cell proliferation#GO:0030888;regulation of leukocyte proliferation#GO:0070663;negative regulation of multicellular organismal process#GO:0051241;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;regulation of immune effector process#GO:0002697;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;immune response#GO:0006955;regulation of cytokine production#GO:0001817;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;negative regulation of immune system process#GO:0002683;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of immune effector process#GO:0002699;regulation of lymphocyte proliferation#GO:0050670;multicellular organismal process#GO:0032501;negative regulation of cellular process#GO:0048523;defense response#GO:0006952;regulation of biosynthetic process#GO:0009889;negative regulation of cell activation#GO:0050866 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004654.3|UniProtKB=G3QPR1 G3QPR1 ZMYND12 PTHR46533:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 GORGO|Ensembl=ENSGGOG00000001510.3|UniProtKB=G3QGN1 G3QGN1 FTMT PTHR11431:SF30 FERRITIN FERRITIN, MITOCHONDRIAL transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000039357.1|UniProtKB=A0A2I2Y458 A0A2I2Y458 PTHR10978:SF2 SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT SUCCINATE DEHYDROGENASE COMPLEX SUBUNIT C metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494 dehydrogenase#PC00092 TCA cycle#P00051>Succinate Dehydrogenase#P01273 GORGO|Ensembl=ENSGGOG00000006055.3|UniProtKB=G3QTA6 G3QTA6 PTHR24366:SF70 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS RETICULON 4 RECEPTOR immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000004194.3|UniProtKB=G3QNK7 G3QNK7 MORC1 PTHR23337:SF6 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1 MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002627.3|UniProtKB=A0A2I2ZGQ9 A0A2I2ZGQ9 TOR3A PTHR10760:SF3 TORSIN TORSIN-3A organelle envelope#GO:0031967;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000022174.2|UniProtKB=A0A2I2YH23 A0A2I2YH23 IFNAR1 PTHR20859:SF54 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON ALPHA_BETA RECEPTOR 1 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 cell surface receptor signaling pathway#GO:0007166;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;immune response#GO:0006955;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to other organism#GO:0051707;biological regulation#GO:0065007;type I interferon-mediated signaling pathway#GO:0060337;cytokine-mediated signaling pathway#GO:0019221;immune system process#GO:0002376;cell communication#GO:0007154;response to peptide#GO:1901652;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866 GORGO|Ensembl=ENSGGOG00000027227.2|UniProtKB=G3SID7 G3SID7 CD34 PTHR16677:SF1 HEMATOPOIETIC PROGENITOR CELL ANTIGEN CD34 HEMATOPOIETIC PROGENITOR CELL ANTIGEN CD34 cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell-substrate adhesion#GO:0031589 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000040845.1|UniProtKB=A0A2I2ZX88 A0A2I2ZX88 ZNF154 PTHR24377:SF934 IP01015P-RELATED ZINC FINGER PROTEIN 154 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008943.3|UniProtKB=G3R0Q1 G3R0Q1 MOCS1 PTHR22960:SF26 MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000004170.3|UniProtKB=G3QNH6 G3QNH6 TMPRSS12 PTHR24253:SF146 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 12 serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015546.3|UniProtKB=G3RHP2 G3RHP2 EIF2S2 PTHR23001:SF24 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2 translation initiation factor activity#GO:0003743;translation initiation factor binding#GO:0031369;translation factor activity#GO:0180051;RNA binding#GO:0003723;protein binding#GO:0005515;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;cytoplasmic translational initiation#GO:0002183;translational initiation#GO:0006413;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000013776.3|UniProtKB=A0A2I2Y9X9 A0A2I2Y9X9 EI24 PTHR21389:SF0 P53 INDUCED PROTEIN ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG metabolic process#GO:0008152;cellular process#GO:0009987;autophagy#GO:0006914;catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013831.3|UniProtKB=G3RDA3 G3RDA3 RHOT2 PTHR24072:SF311 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE 2 ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;apoptotic signaling pathway#GO:0097190;establishment of localization#GO:0051234;actin filament organization#GO:0007015;mitochondrion localization#GO:0051646;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;actin cytoskeleton organization#GO:0030036;organelle localization#GO:0051640;actin filament-based process#GO:0030029;cell communication#GO:0007154;localization#GO:0051179;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;regulation of membrane permeability#GO:0090559;mitochondrion organization#GO:0007005;cytoskeleton organization#GO:0007010;apoptotic mitochondrial changes#GO:0008637;organelle transport along microtubule#GO:0072384;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;response to stimulus#GO:0050896;establishment of organelle localization#GO:0051656;signaling#GO:0023052;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;regulation of biological quality#GO:0065008 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000037983.1|UniProtKB=A0A2I2ZI05 A0A2I2ZI05 TRMT9B PTHR13069:SF36 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 TRNA METHYLTRANSFERASE 9B-RELATED transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;methyltransferase activity#GO:0008168;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049;catalytic activity, acting on a tRNA#GO:0140101 nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000043956.1|UniProtKB=A0A2I2ZWT4 A0A2I2ZWT4 PTHR13337:SF6 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;primary metabolic process#GO:0044238;electron transport chain#GO:0022900;tricarboxylic acid cycle#GO:0006099;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646 membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000000683.3|UniProtKB=G3QEH8 G3QEH8 DNAJB12 PTHR43908:SF8 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY B MEMBER 12 heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular response to misfolded protein#GO:0071218;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 GORGO|Ensembl=ENSGGOG00000016030.3|UniProtKB=A0A2I2YLT0 A0A2I2YLT0 SARDH PTHR13847:SF200 SARCOSINE DEHYDROGENASE-RELATED SARCOSINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000040604.1|UniProtKB=A0A2I2YB43 A0A2I2YB43 PTHR21588:SF22 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6 MICOS COMPLEX SUBUNIT MIC19 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000010476.3|UniProtKB=G3R4L4 G3R4L4 SKI PTHR10005:SF15 SKI ONCOGENE-RELATED SKI ONCOGENE RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of gene expression#GO:0010468;negative regulation of BMP signaling pathway#GO:0030514;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of BMP signaling pathway#GO:0030510 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 GORGO|Ensembl=ENSGGOG00000038270.1|UniProtKB=A0A2I2ZJS1 A0A2I2ZJS1 PTHR10615:SF222 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT7 protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;binding#GO:0005488;acetyltransferase activity#GO:0016407;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;histone acetyltransferase activity#GO:0004402;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137 GORGO|Ensembl=ENSGGOG00000012263.3|UniProtKB=G3R981 G3R981 LOC129529599 PTHR14224:SF110 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 MELANOMA ANTIGEN PREFERENTIALLY EXPRESSED IN TUMORS ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul2-RING ubiquitin ligase complex#GO:0031462;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000016138.3|UniProtKB=G3S6A6 G3S6A6 SNRPB PTHR10701:SF15 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEINS B AND B' ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U4 snRNP#GO:0005687;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000006776.3|UniProtKB=G3QV61 G3QV61 LRRC4C PTHR24369:SF8 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;regulation of axonogenesis#GO:0050770;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of cellular component organization#GO:0051128;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;synapse organization#GO:0050808;cell adhesion#GO:0007155;synaptic membrane adhesion#GO:0099560 cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;glutamatergic synapse#GO:0098978;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000023940.2|UniProtKB=A0A2I2ZA06 A0A2I2ZA06 LOC101130624 PTHR35968:SF1 CHROMOSOME 6 C6ORF201 HOMOLOG TESTIS EXPRESSED PROTEIN 56 GORGO|Ensembl=ENSGGOG00000003666.3|UniProtKB=G3QM73 G3QM73 SAMD10 PTHR20843:SF1 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 10 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000023429.2|UniProtKB=A0A2I2ZKF8 A0A2I2ZKF8 PTHR10064:SF15 60S RIBOSOMAL PROTEIN L22 RIBOSOMAL PROTEIN L22 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000040868.1|UniProtKB=A0A2I2Z2U5 A0A2I2Z2U5 LRP1B PTHR46513:SF7 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LDL RECEPTOR RELATED PROTEIN 1B transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037264.1|UniProtKB=G3RBP3 G3RBP3 LOC101154495 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000005578.3|UniProtKB=G3QS36 G3QS36 MRGPRF PTHR11334:SF3 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER F transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007336.3|UniProtKB=G3SIH8 G3SIH8 SPATS2 PTHR15623:SF10 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2-RELATED SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000000336.4|UniProtKB=G3QDK8 G3QDK8 VSIG4 PTHR15466:SF2 V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 4 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000008716.3|UniProtKB=A0A2I2Z2X6 A0A2I2Z2X6 ZNF385B PTHR23067:SF8 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385B nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000024281.2|UniProtKB=G3RXR5 G3RXR5 PTH PTHR10541:SF2 PARATHYROID HORMONE PARATHYROID HORMONE receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 intracellular calcium ion homeostasis#GO:0006874;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;chemical homeostasis#GO:0048878;regulation of multicellular organismal process#GO:0051239;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;renal system process#GO:0003014;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;G protein-coupled receptor signaling pathway#GO:0007186;inorganic ion homeostasis#GO:0098771;response to stimulus#GO:0050896;signaling#GO:0023052;intracellular monoatomic ion homeostasis#GO:0006873;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;renal absorption#GO:0070293;cellular homeostasis#GO:0019725;system process#GO:0003008;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;positive regulation of developmental process#GO:0051094;multicellular organismal process#GO:0032501;regulation of bone mineralization#GO:0030500;biological regulation#GO:0065007;cell communication#GO:0007154;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;homeostatic process#GO:0042592;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000036410.1|UniProtKB=A0A2I2YR58 A0A2I2YR58 ARHGEF39 PTHR47056:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39 regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000008989.3|UniProtKB=G3RYR9 G3RYR9 IRAK4 PTHR24419:SF35 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to biotic stimulus#GO:0071216;cell cycle#GO:0007049;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;cell surface receptor signaling pathway#GO:0007166;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;response to lipopolysaccharide#GO:0032496;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>IRAK4#P01342 GORGO|Ensembl=ENSGGOG00000001422.3|UniProtKB=G3S9V3 G3S9V3 PTHR16231:SF13 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN CONTAINING 4 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;response to tumor necrosis factor#GO:0034612;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000011496.3|UniProtKB=G3R782 G3R782 LOC101127636 PTHR24286:SF191 CYTOCHROME P450 26 LANOSTEROL 14-ALPHA DEMETHYLASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;secondary alcohol biosynthetic process#GO:1902653 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000025335.2|UniProtKB=G3RXB9 G3RXB9 UTP3 PTHR13237:SF8 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED SOMETHING ABOUT SILENCING PROTEIN 10 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467 small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013028.3|UniProtKB=A0A2I2ZH87 A0A2I2ZH87 DCAF8 PTHR15574:SF57 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 8 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000006068.3|UniProtKB=G3RVL6 G3RVL6 ADAM32 PTHR11905:SF24 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 32 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cell-cell recognition#GO:0009988;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;male sex differentiation#GO:0046661;metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;sperm-egg recognition#GO:0035036;gonad development#GO:0008406;multicellular organismal process#GO:0032501;male gonad development#GO:0008584;sex differentiation#GO:0007548;cellular process#GO:0009987;single fertilization#GO:0007338;system development#GO:0048731;reproductive system development#GO:0061458;binding of sperm to zona pellucida#GO:0007339;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;cell adhesion#GO:0007155;sexual reproduction#GO:0019953;cell recognition#GO:0008037;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;reproductive process#GO:0022414;fertilization#GO:0009566;reproductive structure development#GO:0048608;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000006997.3|UniProtKB=G3QVR3 G3QVR3 CCDC185 PTHR33663:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 177 COILED-COIL DOMAIN-CONTAINING PROTEIN 185 GORGO|Ensembl=ENSGGOG00000005724.3|UniProtKB=A0A2I2Z4Q5 A0A2I2Z4Q5 NR1I3 PTHR48092:SF23 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 3 transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000013864.3|UniProtKB=A0A2I2ZLM5 A0A2I2ZLM5 MYH10 PTHR45615:SF24 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-10 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824 regulation of biological quality#GO:0065008;cytoskeleton-dependent cytokinesis#GO:0061640;actin filament-based process#GO:0030029;cytokinesis#GO:0000910;regulation of developmental process#GO:0050793;actomyosin structure organization#GO:0031032;mitotic cell cycle#GO:0000278;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of cell shape#GO:0008360;cell division#GO:0051301;cell cycle#GO:0007049;cellular component organization#GO:0016043;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996 actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 GORGO|Ensembl=ENSGGOG00000000715.3|UniProtKB=G3QEK6 G3QEK6 ZNF410 PTHR24390:SF74 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 410 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000043392.1|UniProtKB=A0A2I2YGG9 A0A2I2YGG9 PTHR15909:SF0 39S RIBOSOMAL PROTEIN L35, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000043092.1|UniProtKB=A0A2I2YMJ4 A0A2I2YMJ4 EBP PTHR14207:SF8 STEROL ISOMERASE 3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity#GO:0003824 secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000004873.3|UniProtKB=G3QQA9 G3QQA9 CBX7 PTHR47277:SF1 CHROMOBOX PROTEIN HOMOLOG 7 CHROMOBOX PROTEIN HOMOLOG 7 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000007816.3|UniProtKB=A0A2I2Z049 A0A2I2Z049 EPG5 PTHR31139:SF4 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG ECTOPIC P GRANULES PROTEIN 5 HOMOLOG vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000017032.3|UniProtKB=G3RLH5 G3RLH5 PTHR24251:SF47 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN 2 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000015987.4|UniProtKB=G3RIT7 G3RIT7 DYNC1LI1 PTHR12688:SF2 DYNEIN LIGHT INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based movement#GO:0007018;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 kinetochore#GO:0000776;dynein complex#GO:0030286;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule organizing center#GO:0005815;centrosome#GO:0005813;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000003399.3|UniProtKB=G3SHP7 G3SHP7 CUL5 PTHR11932:SF76 CULLIN CULLIN-5 ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198;protein binding#GO:0005515;enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000024203.2|UniProtKB=G3S9X8 G3S9X8 PTHR23239:SF361 INTERMEDIATE FILAMENT IF ROD DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;organelle organization#GO:0006996;intermediate filament-based process#GO:0045103;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;intermediate filament cytoskeleton organization#GO:0045104 organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000000605.3|UniProtKB=G3QEA4 G3QEA4 CEP85 PTHR31075:SF3 CENTROSOMAL PROTEIN OF 85 KDA CENTROSOMAL PROTEIN OF 85 KDA intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815 GORGO|Ensembl=ENSGGOG00000012558.3|UniProtKB=G3RA06 G3RA06 TTC24 PTHR47050:SF2 TETRATRICOPEPTIDE REPEAT PROTEIN 24 TETRATRICOPEPTIDE REPEAT PROTEIN 24 GORGO|Ensembl=ENSGGOG00000042353.1|UniProtKB=A0A2I2YXP9 A0A2I2YXP9 RNF216 PTHR22770:SF47 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF216 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of endocytosis#GO:0030100;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;cell junction#GO:0030054;intracellular protein-containing complex#GO:0140535;postsynapse#GO:0098794;presynapse#GO:0098793;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000028537.2|UniProtKB=G3RY84 G3RY84 MAML1 PTHR15692:SF19 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 Notch signaling pathway#P00045>Mastermind#P01106 GORGO|Ensembl=ENSGGOG00000038572.1|UniProtKB=A0A2I2YUP7 A0A2I2YUP7 TMEM88B PTHR28628:SF2 TRANSMEMBRANE PROTEIN 88-RELATED TRANSMEMBRANE PROTEIN 278 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000028004.2|UniProtKB=G3SIW2 G3SIW2 NTAN1 PTHR12498:SF0 N-TERMINAL ASPARAGINE AMIDOHYDROLASE PROTEIN N-TERMINAL ASPARAGINE AMIDOHYDROLASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003570.3|UniProtKB=A0A2I2ZLM6 A0A2I2ZLM6 ACLY PTHR23118:SF42 ATP-CITRATE SYNTHASE ATP-CITRATE SYNTHASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 organophosphate biosynthetic process#GO:0090407;oxoacid metabolic process#GO:0043436;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;monocarboxylic acid biosynthetic process#GO:0072330;nucleoside phosphate biosynthetic process#GO:1901293;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound biosynthetic process#GO:0034654;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220 Pyruvate metabolism#P02772>Citrate Lyase#P03137 GORGO|Ensembl=ENSGGOG00000015706.3|UniProtKB=G3RI41 G3RI41 RALGPS1 PTHR23113:SF167 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000004681.3|UniProtKB=G3S8U6 G3S8U6 KAT6A PTHR10615:SF26 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT6A transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;binding#GO:0005488;acetyltransferase activity#GO:0016407;transcription regulator activity#GO:0140110;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000022335.2|UniProtKB=G3RTD8 G3RTD8 LOC109023087 PTHR46077:SF3 E3 UBIQUITIN-PROTEIN LIGASE TOPORS RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000022953.2|UniProtKB=G3RNQ1 G3RNQ1 PRG4 PTHR22917:SF1 HEMOPEXIN DOMAIN-CONTAINING PROTEIN PROTEOGLYCAN 4 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000004745.3|UniProtKB=G3QPZ7 G3QPZ7 GTF3C2 PTHR15052:SF2 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR COMPLEX SUBUNIT GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 2 rDNA binding#GO:0000182;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA transcription#GO:0009303;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transcription factor TFIIIC complex#GO:0000127;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000027257.2|UniProtKB=G3S008 G3S008 AASS PTHR11133:SF28 SACCHAROPINE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000024421.2|UniProtKB=A0A2I2ZJ97 A0A2I2ZJ97 ST3GAL5 PTHR13713:SF60 SIALYLTRANSFERASE LACTOSYLCERAMIDE ALPHA-2,3-SIALYLTRANSFERASE glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000016072.3|UniProtKB=G3RT59 G3RT59 POLA1 PTHR45861:SF1 DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA replication origin binding#GO:0003688;binding#GO:0005488;single-stranded DNA binding#GO:0003697;transferase activity#GO:0016740;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;DNA-directed DNA polymerase activity#GO:0003887;double-stranded DNA binding#GO:0003690;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;sequence-specific double-stranded DNA binding#GO:1990837 DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated DNA replication#GO:0006261;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;replisome#GO:0030894;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 DNA replication#P00017>Pol alpha#P00531 GORGO|Ensembl=ENSGGOG00000004442.3|UniProtKB=G3QP69 G3QP69 ARL11 PTHR11711:SF172 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 11 purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000009719.3|UniProtKB=G3R2N5 G3R2N5 ATP5F1C PTHR11693:SF31 ATP SYNTHASE GAMMA CHAIN ATP SYNTHASE F(1) COMPLEX SUBUNIT GAMMA, MITOCHONDRIAL channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078 ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002 ATP synthesis#P02721>F1 gamma#P02796 GORGO|Ensembl=ENSGGOG00000012233.3|UniProtKB=G3R967 G3R967 DNAJC10 PTHR44340:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 10 ENDOPLASMIC RETICULUM DISULFIDE REDUCTASE DNAJC10 protein-disulfide reductase activity#GO:0015035;protein binding#GO:0005515;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824 endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000004986.3|UniProtKB=A0A2I2YNR3 A0A2I2YNR3 SLC12A4 PTHR11827:SF46 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 4 metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000025082.2|UniProtKB=G3SHW8 G3SHW8 RPL23 PTHR11761:SF22 50S/60S RIBOSOMAL PROTEIN L14/L23 LARGE RIBOSOMAL SUBUNIT PROTEIN UL14 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000037139.1|UniProtKB=P47778 P47778 RNASE3 PTHR11437:SF68 RIBONUCLEASE EOSINOPHIL CATIONIC PROTEIN catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098 response to chemical#GO:0042221;taxis#GO:0042330;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;defense response to Gram-positive bacterium#GO:0050830;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;chemotaxis#GO:0006935 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000041391.1|UniProtKB=A0A2I2YEU1 A0A2I2YEU1 PTHR23266:SF275 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-24 binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000016442.3|UniProtKB=G3RJY5 G3RJY5 ZNF174 PTHR23226:SF175 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 174 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000037416.1|UniProtKB=A0A2I2Z3X1 A0A2I2Z3X1 TFAM PTHR48112:SF36 HIGH MOBILITY GROUP PROTEIN DSP1 TRANSCRIPTION FACTOR A, MITOCHONDRIAL transcription regulator activity#GO:0140110 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;mitochondrial transcription#GO:0006390;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial nucleoid#GO:0042645;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoid#GO:0009295;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000009745.3|UniProtKB=G3R2Q7 G3R2Q7 MEPE PTHR16510:SF4 EXTRACELLULAR MATRIX PHOSPHOGLYCOPROTEIN WITH ASARM MOTIF MATRIX EXTRACELLULAR PHOSPHOGLYCOPROTEIN binding#GO:0005488;protein binding#GO:0005515 anatomical structure development#GO:0048856;tissue development#GO:0009888;animal organ development#GO:0048513;developmental process#GO:0032502;biomineral tissue development#GO:0031214;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000036889.1|UniProtKB=A0A2I2ZU65 A0A2I2ZU65 ULBP1 PTHR16675:SF268 MHC CLASS I-RELATED UL16-BINDING PROTEIN 1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 immune effector process#GO:0002252;natural killer cell mediated cytotoxicity#GO:0042267;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;regulation of biological process#GO:0050789;natural killer cell mediated immunity#GO:0002228;leukocyte mediated cytotoxicity#GO:0001909;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;cell killing#GO:0001906;positive regulation of leukocyte mediated immunity#GO:0002705;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of immune effector process#GO:0002699;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated immunity#GO:0002703;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000005676.3|UniProtKB=G3S377 G3S377 APBA2 PTHR12345:SF12 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 2 peptide binding#GO:0042277;binding#GO:0005488 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;cellular process#GO:0009987;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536 cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cell projection#GO:0042995;postsynapse#GO:0098794;dendritic spine#GO:0043197;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093;Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084 GORGO|Ensembl=ENSGGOG00000007382.3|UniProtKB=A0A2I2ZF81 A0A2I2ZF81 TBL2 PTHR44321:SF1 TRANSDUCIN BETA-LIKE PROTEIN 2 TRANSDUCIN BETA-LIKE PROTEIN 2 cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000013723.3|UniProtKB=G3RQF4 G3RQF4 PTHR11738:SF86 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;regulation of immune response#GO:0050776;response to chemical#GO:0042221;response to cytokine#GO:0034097;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000040048.1|UniProtKB=A0A2I2YMA5 A0A2I2YMA5 CA9 PTHR18952:SF18 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 9 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000042248.1|UniProtKB=A0A2I2YTI4 A0A2I2YTI4 PTHR15469:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B15 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000015127.3|UniProtKB=G3RGM1 G3RGM1 SLC30A5 PTHR45755:SF1 FAMILY NOT NAMED PROTON-COUPLED ZINC ANTIPORTER SLC30A5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810 Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;Golgi cis cisterna#GO:0000137;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;Golgi stack#GO:0005795;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000028298.2|UniProtKB=G3RU70 G3RU70 TBPL1 PTHR10126:SF69 TATA-BOX BINDING PROTEIN TATA BOX-BINDING PROTEIN-LIKE 1 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;General transcription by RNA polymerase I#P00022>TBP#P00657;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription regulation#P00023>TBP#P00670 GORGO|Ensembl=ENSGGOG00000023830.2|UniProtKB=A0A2I2Y4C0 A0A2I2Y4C0 PTHR22761:SF52 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 5 localization#GO:0051179;cellular localization#GO:0051641;late endosome to vacuole transport#GO:0045324;membrane assembly#GO:0071709;cellular component organization#GO:0016043;endosomal transport#GO:0016197;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;nuclear membrane organization#GO:0071763;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000041931.1|UniProtKB=A0A2I2Z2C4 A0A2I2Z2C4 CLDN9 PTHR12002:SF42 CLAUDIN CLAUDIN-9 binding#GO:0005488;virus receptor activity#GO:0001618;protein binding#GO:0005515 cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000007100.3|UniProtKB=G3QW05 G3QW05 RCSD1 PTHR21669:SF2 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS CAPZ-INTERACTING PROTEIN protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543 macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to organelle#GO:0033365;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040159.1|UniProtKB=A0A2I2ZWB5 A0A2I2ZWB5 IGIP PTHR39224:SF1 IGA-INDUCING PROTEIN HOMOLOG IGA-INDUCING PROTEIN HOMOLOG GORGO|Ensembl=ENSGGOG00000041470.1|UniProtKB=A0A2I2Y1V5 A0A2I2Y1V5 SERF2 PTHR13596:SF6 SMALL EDRK-RICH FACTOR 1 SMALL EDRK-RICH FACTOR 2 GORGO|Ensembl=ENSGGOG00000000863.3|UniProtKB=G3RMN3 G3RMN3 KIF13B PTHR24115:SF978 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF13B cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000013978.3|UniProtKB=G3RDM5 G3RDM5 PPP2CB PTHR45619:SF44 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT BETA ISOFORM protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260;protein phosphatase#PC00195 p53 pathway feedback loops 2#P04398>PP2A-C#P04659;FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;p53 pathway#P00059>PP2A#P04630;EGF receptor signaling pathway#P00018>PP2A#P00547 GORGO|Ensembl=ENSGGOG00000028519.2|UniProtKB=G3RT09 G3RT09 MC3R PTHR22750:SF4 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 3 hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000042229.1|UniProtKB=A0A2I2ZYU5 A0A2I2ZYU5 PTHR24353:SF134 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE PROTEIN KINASE X-LINKED protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell adhesion#GO:0007155;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000009530.3|UniProtKB=G3R270 G3R270 COBL PTHR47008:SF1 PROTEIN CORDON-BLEU PROTEIN CORDON-BLEU protein binding#GO:0005515;actin monomer binding#GO:0003785;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;neuron projection#GO:0043005;cell leading edge#GO:0031252;actin filament#GO:0005884;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell body#GO:0044297;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;axonal growth cone#GO:0044295;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell periphery#GO:0071944;membrane#GO:0016020;ruffle#GO:0001726;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuronal cell body#GO:0043025;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;growth cone#GO:0030426;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425 GORGO|Ensembl=ENSGGOG00000023995.2|UniProtKB=G3RUF1 G3RUF1 UPF3B PTHR13112:SF1 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN REGULATOR OF NONSENSE TRANSCRIPTS 3B mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;positive regulation of protein metabolic process#GO:0051247;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000013772.3|UniProtKB=A0A2I2ZBM5 A0A2I2ZBM5 HPSE2 PTHR46145:SF1 HEPARANASE INACTIVE HEPARANASE-2 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000037830.1|UniProtKB=A0A2I2Y9F3 A0A2I2Y9F3 TXNL4B PTHR12052:SF4 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4B RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000042679.1|UniProtKB=A0A2I2ZBF2 A0A2I2ZBF2 TGFA PTHR10740:SF1 TRANSFORMING GROWTH FACTOR ALPHA PROTRANSFORMING GROWTH FACTOR ALPHA receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840;regulation of mitotic nuclear division#GO:0007088;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of nuclear division#GO:0051783;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cellular component organization#GO:0051130;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of cell population proliferation#GO:0008284;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of cell cycle#GO:0051726 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 GORGO|Ensembl=ENSGGOG00000038328.1|UniProtKB=A0A2I2Y8B3 A0A2I2Y8B3 SSBP3 PTHR12610:SF22 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000010481.3|UniProtKB=G3R4M3 G3R4M3 SON PTHR46528:SF1 PROTEIN SON PROTEIN SON nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000028292.2|UniProtKB=G3S1Y1 G3S1Y1 POM121L2 PTHR23193:SF20 NUCLEAR PORE COMPLEX PROTEIN NUP POM121-LIKE PROTEIN 2 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008976.3|UniProtKB=G3R0S5 G3R0S5 PTHR16231:SF5 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 6 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cell surface receptor signaling pathway#GO:0007166;response to tumor necrosis factor#GO:0034612;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000002159.3|UniProtKB=G3QIC0 G3QIC0 CASR PTHR24061:SF358 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR calcium ion binding#GO:0005509;transmembrane signaling receptor activity#GO:0004888;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;molecular transducer activity#GO:0060089;metal ion binding#GO:0046872;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930 response to calcium ion#GO:0051592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;detection of chemical stimulus#GO:0009593;intracellular monoatomic ion homeostasis#GO:0006873;regulation of transport#GO:0051049;regulation of localization#GO:0032879;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;response to metal ion#GO:0010038;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;response to chemical#GO:0042221;detection of stimulus#GO:0051606;monoatomic ion homeostasis#GO:0050801 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000448.3|UniProtKB=G3QDW2 G3QDW2 NLRP14 PTHR45690:SF15 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 14 biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of response to stress#GO:0080134 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000006386.3|UniProtKB=G3QU51 G3QU51 LGALSL PTHR11346:SF98 GALECTIN GALECTIN-RELATED PROTEIN binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000011705.3|UniProtKB=G3SF49 G3SF49 NPDC1 PTHR23352:SF2 NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN-1 NPDC-1 PROTEIN NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN 1 GORGO|Ensembl=ENSGGOG00000022422.2|UniProtKB=G3SGG2 G3SGG2 RGL3 PTHR23113:SF220 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 3 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000009083.3|UniProtKB=G3R139 G3R139 REPS1 PTHR11216:SF63 EH DOMAIN RALBP1-ASSOCIATED EPS DOMAIN-CONTAINING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015288.3|UniProtKB=A0A2I2YY08 A0A2I2YY08 USP3 PTHR21646:SF19 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 3 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of protein stability#GO:0031647;response to stress#GO:0006950;regulation of biological quality#GO:0065008;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000007318.3|UniProtKB=G3QWK1 G3QWK1 SDS PTHR48078:SF8 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED L-SERINE DEHYDRATASE_L-THREONINE DEAMINASE catalytic activity#GO:0003824;lyase activity#GO:0016829 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;branched-chain amino acid biosynthetic process#GO:0009082 dehydratase#PC00091;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000001947.3|UniProtKB=G3QHT2 G3QHT2 TTLL6 PTHR12241:SF96 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL6 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;binding#GO:0005488 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule bundle formation#GO:0001578;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000025684.2|UniProtKB=G3RUW6 G3RUW6 PTHR23266:SF389 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-70-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000004453.3|UniProtKB=G3QP80 G3QP80 EAF1 PTHR15970:SF8 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR 1 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015270.3|UniProtKB=G3RGZ7 G3RGZ7 EIF2D PTHR12217:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 2D EUKARYOTIC TRANSLATION INITIATION FACTOR 2D translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000007614.3|UniProtKB=G3QXB1 G3QXB1 LOC101125582 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN GORGO|Ensembl=ENSGGOG00000002967.3|UniProtKB=G3QKE3 G3QKE3 FGF23 PTHR11486:SF69 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 23 growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 GORGO|Ensembl=ENSGGOG00000004187.3|UniProtKB=G3QNJ3 G3QNJ3 NLGN1 PTHR43903:SF2 NEUROLIGIN NEUROLIGIN-1 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000014580.3|UniProtKB=G3RF68 G3RF68 OSMR PTHR23036:SF95 CYTOKINE RECEPTOR ONCOSTATIN-M-SPECIFIC RECEPTOR SUBUNIT BETA cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004246.3|UniProtKB=G3QNP7 G3QNP7 RPRD1B PTHR12460:SF3 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 1B binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000015498.3|UniProtKB=G3RHJ7 G3RHJ7 BHLHE41 PTHR10985:SF76 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 41 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;rhythmic process#GO:0048511;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;pattern specification process#GO:0007389;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000006537.3|UniProtKB=G3QUJ1 G3QUJ1 LOC101128939 PTHR22802:SF245 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER G molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000010773.3|UniProtKB=G3R5D7 G3R5D7 GATA4 PTHR10071:SF154 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-4 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>GATA2/4#P06859 GORGO|Ensembl=ENSGGOG00000036324.1|UniProtKB=A0A2I2ZH96 A0A2I2ZH96 LOC101151578 PTHR11588:SF309 TUBULIN TUBULIN BETA CHAIN ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 GORGO|Ensembl=ENSGGOG00000025765.2|UniProtKB=G3RM63 G3RM63 PTPN13 PTHR46900:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488;phosphatidylinositol 3-kinase binding#GO:0043548 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of synapse assembly#GO:0051963;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;regulation of biological quality#GO:0065008;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000006577.3|UniProtKB=G3QUM9 G3QUM9 PTHR37357:SF1 IZUMO SPERM-EGG FUSION PROTEIN 4 IZUMO SPERM-EGG FUSION PROTEIN 4 GORGO|Ensembl=ENSGGOG00000002296.3|UniProtKB=G3SJH8 G3SJH8 MAPK8IP1 PTHR47437:SF3 JNK-INTERACTING PROTEIN 1-LIKE PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 1 protein complex scaffold activity#GO:0140378;molecular adaptor activity#GO:0060090;structural molecule activity#GO:0005198;MAP kinase scaffold activity#GO:0005078;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515;signaling adaptor activity#GO:0035591 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000036672.1|UniProtKB=A0A2I2Z4S5 A0A2I2Z4S5 PTHR45699:SF11 60S ACIDIC RIBOSOMAL PROTEIN P0 LARGE RIBOSOMAL SUBUNIT PROTEIN UL10-LIKE INSERTION DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000001032.3|UniProtKB=G3SCW8 G3SCW8 BLNK PTHR14098:SF3 SH2 DOMAIN CONTAINING PROTEIN B-CELL LINKER PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;immune system process#GO:0002376;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of immune response#GO:0050776;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;B cell receptor signaling pathway#GO:0050853;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 B cell activation#P00010>BLNK#P00394 GORGO|Ensembl=ENSGGOG00000023767.2|UniProtKB=G3S8Y3 G3S8Y3 PTHR46289:SF5 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED THAP-TYPE DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000006209.3|UniProtKB=G3QTQ3 G3QTQ3 MAGI3 PTHR10316:SF10 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cell-cell junction#GO:0005911;cell junction#GO:0030054;adherens junction#GO:0005912;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000015517.3|UniProtKB=G3RHL7 G3RHL7 DPH6 PTHR12196:SF2 DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN DIPHTHINE--AMMONIA LIGASE catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000014054.3|UniProtKB=G3RDU8 G3RDU8 PTHR46448:SF3 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN EXTRACELLULAR TYROSINE-PROTEIN KINASE PKDCC GORGO|Ensembl=ENSGGOG00000014263.3|UniProtKB=G3REE1 G3REE1 PDE9A PTHR11347:SF236 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 9A catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112 negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;ribonucleotide metabolic process#GO:0009259;regulation of signaling#GO:0023051;nucleotide metabolic process#GO:0009117;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;negative regulation of cellular process#GO:0048523;nucleotide catabolic process#GO:0009166;cyclic nucleotide metabolic process#GO:0009187;regulation of response to stimulus#GO:0048583;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;negative regulation of response to stimulus#GO:0048585;nucleobase-containing compound metabolic process#GO:0006139;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000000760.3|UniProtKB=G3QEP9 G3QEP9 CNFN PTHR15907:SF26 DUF614 FAMILY PROTEIN-RELATED CORNIFELIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Gene=MSTN|UniProtKB=A1C2V5 A1C2V5 MSTN PTHR11848:SF150 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 8 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;tissue development#GO:0009888;signal transduction#GO:0007165;skeletal muscle tissue development#GO:0007519;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;animal organ development#GO:0048513;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;muscle organ development#GO:0007517;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;muscle tissue development#GO:0060537;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;response to transforming growth factor beta#GO:0071559;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000024015.1|UniProtKB=G3S3T4 G3S3T4 CYTB PTHR19271:SF42 CYTOCHROME B CYTOCHROME B active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775 respiratory chain complex III#GO:0045275;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 GORGO|Ensembl=ENSGGOG00000001786.3|UniProtKB=G3QHD4 G3QHD4 KLHL2 PTHR24412:SF155 KELCH PROTEIN KELCH-LIKE PROTEIN 2 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026354.2|UniProtKB=G3S092 G3S092 SFPQ PTHR23189:SF51 RNA RECOGNITION MOTIF-CONTAINING SPLICING FACTOR, PROLINE- AND GLUTAMINE-RICH binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;alternative mRNA splicing, via spliceosome#GO:0000380 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006550.3|UniProtKB=G3SFG7 G3SFG7 CYRIB PTHR12422:SF3 GH09096P CYFIP-RELATED RAC1 INTERACTOR B positive regulation of lymphocyte activation#GO:0051251;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;positive regulation of cell adhesion#GO:0045785;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of leukocyte activation#GO:0002696;regulation of T cell activation#GO:0050863;regulation of cell adhesion#GO:0030155;positive regulation of T cell activation#GO:0050870;regulation of multicellular organismal process#GO:0051239;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 GORGO|Ensembl=ENSGGOG00000003906.3|UniProtKB=G3S1V3 G3S1V3 PI16 PTHR10334:SF613 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 16 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015585.3|UniProtKB=G3RHS7 G3RHS7 MARCO PTHR24023:SF1083 COLLAGEN ALPHA MACROPHAGE RECEPTOR MARCO structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000013692.3|UniProtKB=G3SK79 G3SK79 PTGES2 PTHR12782:SF5 MICROSOMAL PROSTAGLANDIN E SYNTHASE-2 PROSTAGLANDIN E SYNTHASE 2 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 reductase#PC00198;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000024676.2|UniProtKB=G3SKC1 G3SKC1 MOS PTHR23257:SF706 SERINE-THREONINE PROTEIN KINASE PROTO-ONCOGENE SERINE_THREONINE-PROTEIN KINASE MOS transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cell cycle process#GO:0010948;regulation of response to stimulus#GO:0048583;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of chromosome separation#GO:1905819;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;regulation of MAPK cascade#GO:0043408;negative regulation of chromosome segregation#GO:0051985;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000004338.3|UniProtKB=G3SEL5 G3SEL5 SGK2 PTHR24351:SF243 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000039363.1|UniProtKB=A0A2I2Z978 A0A2I2Z978 PTHR11177:SF82 CHITINASE CHITINASE-3-LIKE PROTEIN 2 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000003034.3|UniProtKB=G3S2Y5 G3S2Y5 CCSER2 PTHR22461:SF2 SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2-RELATED SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule bundle formation#GO:0001578 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000003915.3|UniProtKB=G3QMU6 G3QMU6 SLC22A6 PTHR24064:SF294 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 6 active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 multicellular organismal process#GO:0032501;lipid transport#GO:0006869;macromolecule localization#GO:0033036;renal system process#GO:0003014;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;system process#GO:0003008;lipid localization#GO:0010876;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000006619.3|UniProtKB=G3QUS1 G3QUS1 RAB41 PTHR24073:SF469 DRAB5-RELATED RAS-RELATED PROTEIN RAB-41 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;cytosolic transport#GO:0016482;protein localization to organelle#GO:0033365;intra-Golgi vesicle-mediated transport#GO:0006891;protein localization to membrane#GO:0072657;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000008875.3|UniProtKB=A0A2I2Y8R2 A0A2I2Y8R2 SEC61A2 PTHR10906:SF10 SECY/SEC61-ALPHA FAMILY MEMBER PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 2 protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;transmembrane protein transporter activity#GO:0008320;ribonucleoprotein complex binding#GO:0043021;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;binding#GO:0005488 establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein transmembrane transport#GO:0071806;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;post-translational protein targeting to membrane, translocation#GO:0031204;protein transport#GO:0015031;localization within membrane#GO:0051668;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;rough endoplasmic reticulum#GO:0005791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011623.3|UniProtKB=G3RY67 G3RY67 UNC5B PTHR12582:SF6 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 GORGO|Ensembl=ENSGGOG00000013766.4|UniProtKB=A0A2I2ZRH6 A0A2I2ZRH6 DGKB PTHR11255:SF32 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE BETA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000007918.3|UniProtKB=G3QY19 G3QY19 RHOU PTHR24072:SF148 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOU heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;transport#GO:0006810;actin filament organization#GO:0007015;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Axon guidance mediated by netrin#P00009>cdc42#P00364;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515 GORGO|Ensembl=ENSGGOG00000012183.3|UniProtKB=G3R920 G3R920 STRADB PTHR48014:SF13 SERINE/THREONINE-PROTEIN KINASE FRAY2 STE20-RELATED KINASE ADAPTER PROTEIN BETA kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887 nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein export from nucleus#GO:0006611 protein-containing complex#GO:0032991;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000036501.1|UniProtKB=G3QKW7 G3QKW7 OR52K2 PTHR26450:SF404 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010732.3|UniProtKB=A0A2I2ZKK2 A0A2I2ZKK2 PDE4C PTHR11347:SF135 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4C hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 hydrolase#PC00121;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000028013.2|UniProtKB=A0A2I2YW56 A0A2I2YW56 PTHR12504:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 SUBFAMILY NOT NAMED mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024592.2|UniProtKB=G3SJI3 G3SJI3 LOC101141135 PTHR12396:SF56 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN-CONTAINING PROTEIN negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000006372.3|UniProtKB=A0A2I2Z8E0 A0A2I2Z8E0 RBM20 PTHR15592:SF11 MATRIN 3/NUCLEAR PROTEIN 220-RELATED RNA-BINDING PROTEIN 20 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000015769.3|UniProtKB=G3RI87 G3RI87 PTHR24249:SF405 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 8 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000012325.3|UniProtKB=G3R9E3 G3R9E3 PTHR23143:SF19 TRICHOHYALIN-RELATED GOLGIN A6 FAMILY LIKE 10-RELATED actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000041339.1|UniProtKB=G3RSD6 G3RSD6 LOC101145202 PTHR24028:SF69 CADHERIN-87A PROTOCADHERIN BETA-7 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000004702.3|UniProtKB=G3QPV4 G3QPV4 GPSM2 PTHR45954:SF3 LD33695P G PROTEIN-SIGNALING MODULATOR 2 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;binding#GO:0005488 cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;establishment of cell polarity#GO:0030010;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;localization#GO:0051179;spindle localization#GO:0051653;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294 cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>AGS3#P00715;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>AGS3#P00739 GORGO|Ensembl=ENSGGOG00000008069.3|UniProtKB=G3QYF6 G3QYF6 DPAGT1 PTHR10571:SF0 UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000014232.3|UniProtKB=A0A2I2ZPF4 A0A2I2ZPF4 APTX PTHR12486:SF4 APRATAXIN-RELATED APRATAXIN pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;damaged DNA binding#GO:0003684;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;RNA binding#GO:0003723;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;double-stranded RNA binding#GO:0003725;single-stranded DNA binding#GO:0003697 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000002660.3|UniProtKB=A0A2I2ZBM3 A0A2I2ZBM3 DIAPH1 PTHR45691:SF4 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 1 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 GORGO|Ensembl=ENSGGOG00000014944.3|UniProtKB=G3RG41 G3RG41 RELL1 PTHR31037:SF1 RELT-LIKE PROTEIN 1-RELATED RELT-LIKE PROTEIN 1 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000039694.1|UniProtKB=A0A2I2ZMA2 A0A2I2ZMA2 PTHR22780:SF48 ADAPTIN, ALPHA/GAMMA/EPSILON CLATHRIN_COATOMER ADAPTOR ADAPTIN-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810 cytoplasm#GO:0005737;vesicle coat#GO:0030120;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated endocytic vesicle#GO:0045334;clathrin vesicle coat#GO:0030125;coated vesicle membrane#GO:0030662;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;coated vesicle#GO:0030135;endocytic vesicle#GO:0030139;coated membrane#GO:0048475;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117 membrane traffic protein#PC00150 Huntington disease#P00029>alpha-Adaptin#P00782 GORGO|Ensembl=ENSGGOG00000011893.3|UniProtKB=G3R891 G3R891 FBXL8 PTHR16134:SF141 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 8 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000027505.2|UniProtKB=G3SIQ3 G3SIQ3 RAG2 PTHR10960:SF0 V D J RECOMBINATION-ACTIVATING PROTEIN 2 V(D)J RECOMBINATION-ACTIVATING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565 macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;DNA recombination#GO:0006310;developmental process#GO:0032502;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;somatic cell DNA recombination#GO:0016444;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501;cellular process#GO:0009987;system development#GO:0048731;immune system development#GO:0002520;anatomical structure development#GO:0048856;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;V(D)J recombination#GO:0033151;somatic diversification of immune receptors#GO:0002200;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000012147.3|UniProtKB=G3R8X8 G3R8X8 STEAP3 PTHR14239:SF8 DUDULIN-RELATED METALLOREDUCTASE STEAP3 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722;catalytic activity#GO:0003824;ferric-chelate reductase activity#GO:0000293 establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;transport#GO:0006810;transition metal ion transport#GO:0000041 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000007737.3|UniProtKB=G3QXM4 G3QXM4 RYK PTHR24416:SF349 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE RYK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012383.3|UniProtKB=A0A2I2YPT4 A0A2I2YPT4 PARP11 PTHR45740:SF4 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP11 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000010881.3|UniProtKB=G3R5M8 G3R5M8 PSMC3IP PTHR15938:SF0 TBP-1 INTERACTING PROTEIN HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;DNA binding#GO:0003677;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;homologous recombination#GO:0035825;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;homologous chromosome pairing at meiosis#GO:0007129;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;General transcription regulation#P00023>TBP#P00670;General transcription by RNA polymerase I#P00022>SL1 complex#P00653 GORGO|Ensembl=ENSGGOG00000007504.3|UniProtKB=G3QX16 G3QX16 HAUS4 PTHR16219:SF3 AUGMIN SUBUNIT 4 FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 4 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 chromosome segregation#GO:0007059;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652 GORGO|Ensembl=ENSGGOG00000005362.3|UniProtKB=G3QRJ3 G3QRJ3 ARGFX PTHR45793:SF16 HOMEOBOX PROTEIN ARGININE-FIFTY HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000037352.1|UniProtKB=A0A2I2Y9E5 A0A2I2Y9E5 APOC1 PTHR16565:SF2 APOLIPOPROTEIN C-I APOLIPOPROTEIN C-I enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;organic acid binding#GO:0043177;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;molecular function inhibitor activity#GO:0140678;lipid binding#GO:0008289;enzyme regulator activity#GO:0030234;fatty acid binding#GO:0005504 regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;plasma lipoprotein particle clearance#GO:0034381;neutral lipid metabolic process#GO:0006638;regulation of catabolic process#GO:0009894;regulation of localization#GO:0032879;regulation of transport#GO:0051049;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of lipid catabolic process#GO:0050994;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;glycerolipid metabolic process#GO:0046486;negative regulation of metabolic process#GO:0009892;regulation of lipid metabolic process#GO:0019216;negative regulation of catabolic process#GO:0009895 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;very-low-density lipoprotein particle#GO:0034361;plasma lipoprotein particle#GO:0034358;high-density lipoprotein particle#GO:0034364;protein-lipid complex#GO:0032994;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;lipoprotein particle#GO:1990777 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000002721.3|UniProtKB=G3QJS8 G3QJS8 SOWAHD PTHR14491:SF8 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHD GORGO|Ensembl=ENSGGOG00000004327.3|UniProtKB=G3QNW8 G3QNW8 RHOBTB3 PTHR24413:SF239 SPECKLE-TYPE POZ PROTEIN RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000016257.3|UniProtKB=G3RJG9 G3RJG9 CXHXorf58 PTHR33504:SF1 NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4 SIMILAR TO HUMAN CHROMOSOME X OPEN READING FRAME 58 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007514.3|UniProtKB=A0A2I2YQ74 A0A2I2YQ74 PTHR48002:SF29 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008650.3|UniProtKB=A0A2I2YUI3 A0A2I2YUI3 SEMA3F PTHR11036:SF27 SEMAPHORIN SEMAPHORIN-3F molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102 stem cell development#GO:0048864;chemotaxis#GO:0006935;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;mesenchyme development#GO:0060485;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;axon development#GO:0061564;axon guidance#GO:0007411;stem cell differentiation#GO:0048863;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;neural crest cell development#GO:0014032;cell migration#GO:0016477;multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;mesenchymal cell differentiation#GO:0048762;neuron differentiation#GO:0030182;neural crest cell differentiation#GO:0014033;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;neural crest cell migration#GO:0001755;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to chemical#GO:0042221;taxis#GO:0042330;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000011288.3|UniProtKB=G3R6P3 G3R6P3 PRPF38B PTHR23142:SF2 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38B primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011 GORGO|Ensembl=ENSGGOG00000002003.3|UniProtKB=G3SEM4 G3SEM4 HSD17B12 PTHR43899:SF14 RH59310P VERY-LONG-CHAIN 3-OXOACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000043143.1|UniProtKB=A0A2I2Y9M4 A0A2I2Y9M4 MOAP1 PTHR23095:SF14 PARANEOPLASTIC ANTIGEN MODULATOR OF APOPTOSIS 1 regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000016123.3|UniProtKB=G3RTZ4 G3RTZ4 MTR PTHR45833:SF1 METHIONINE SYNTHASE METHIONINE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 S-adenosylmethionine biosynthesis#P02773>Cobalamin-dependent homocysteine transmethylase#P03142;Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024 GORGO|Ensembl=ENSGGOG00000009442.3|UniProtKB=A0A2I2YBP5 A0A2I2YBP5 GALNT6 PTHR11675:SF58 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 6 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000010675.3|UniProtKB=A0A2I2Y6Q5 A0A2I2Y6Q5 HRH2 PTHR24247:SF253 5-HYDROXYTRYPTAMINE RECEPTOR HISTAMINE H2 RECEPTOR G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007925.3|UniProtKB=G3QY25 G3QY25 LOC101140391 PTHR16675:SF148 MHC CLASS I-RELATED UL16-BINDING PROTEIN 2-RELATED molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;natural killer cell mediated immunity#GO:0002228;leukocyte mediated cytotoxicity#GO:0001909;natural killer cell mediated cytotoxicity#GO:0042267;immune effector process#GO:0002252;defense response to other organism#GO:0098542;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte mediated immunity#GO:0002703;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;cell killing#GO:0001906;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of cellular process#GO:0048522 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000014500.3|UniProtKB=G3REZ0 G3REZ0 SPCS2 PTHR13085:SF3 MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 2 protein targeting#GO:0006605;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;localization#GO:0051179;gene expression#GO:0010467;protein maturation#GO:0051604;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;protein targeting to ER#GO:0045047;metabolic process#GO:0008152 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 GORGO|Ensembl=ENSGGOG00000014436.3|UniProtKB=G3RET5 G3RET5 FSHR PTHR24372:SF5 GLYCOPROTEIN HORMONE RECEPTOR FOLLICLE-STIMULATING HORMONE RECEPTOR G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 response to chemical#GO:0042221;response to hormone#GO:0009725;sex differentiation#GO:0007548;cellular process#GO:0009987;male gonad development#GO:0008584;signal transduction#GO:0007165;animal organ development#GO:0048513;multicellular organism development#GO:0007275;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;development of primary sexual characteristics#GO:0045137;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;reproductive structure development#GO:0048608;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;rhythmic process#GO:0048511;multicellular organismal process#GO:0032501;gonad development#GO:0008406;biological regulation#GO:0065007;development of primary male sexual characteristics#GO:0046546;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;male sex differentiation#GO:0046661;developmental process#GO:0032502;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;cell communication#GO:0007154;multicellular organismal reproductive process#GO:0048609;reproductive system development#GO:0061458;female gonad development#GO:0008585;system development#GO:0048731 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000009458.3|UniProtKB=G3R203 G3R203 POU2AF3 PTHR36689:SF1 COLORECTAL CANCER-ASSOCIATED PROTEIN 2 POU CLASS 2 HOMEOBOX ASSOCIATING FACTOR 3 GORGO|Ensembl=ENSGGOG00000022351.2|UniProtKB=G3RXJ3 G3RXJ3 PLEKHF2 PTHR46280:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2 ion binding#GO:0043167;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;anion binding#GO:0043168 endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;endosome organization#GO:0007032;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011826.3|UniProtKB=G3RYY2 G3RYY2 FGF11 PTHR11486:SF67 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 11 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104;ion channel regulator activity#GO:0099106;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;molecular function activator activity#GO:0140677;channel regulator activity#GO:0016247;protein binding#GO:0005515;transporter regulator activity#GO:0141108;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000011035.3|UniProtKB=G3R624 G3R624 POGLUT2 PTHR12203:SF21 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 2 glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007786.3|UniProtKB=G3QXR2 G3QXR2 FCRL1 PTHR11481:SF117 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;immune response#GO:0006955;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376;cell communication#GO:0007154 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015750.3|UniProtKB=G3RI74 G3RI74 TRIM50 PTHR24103:SF326 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM50 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000144.3|UniProtKB=G3QD39 G3QD39 ETV4 PTHR11849:SF181 ETS ETS TRANSLOCATION VARIANT 4 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000009666.3|UniProtKB=G3R2J0 G3R2J0 PTHR11630:SF42 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM5 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097 response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 GORGO|Ensembl=ENSGGOG00000009947.3|UniProtKB=G3R388 G3R388 MSANTD4 PTHR21732:SF0 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 4 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000014070.3|UniProtKB=A0A2I2ZLE8 A0A2I2ZLE8 ORC2 PTHR14052:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA replication origin binding#GO:0003688 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139 chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear origin of replication recognition complex#GO:0005664;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 replication origin binding protein#PC00199 GORGO|Ensembl=ENSGGOG00000004510.3|UniProtKB=G3QPC8 G3QPC8 TFPI2 PTHR10083:SF352 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED TISSUE FACTOR PATHWAY INHIBITOR 2 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000040053.1|UniProtKB=A0A2I2Y5Q6 A0A2I2Y5Q6 TMEM106B PTHR28556:SF1 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106B dendrite development#GO:0016358;cellular localization#GO:0051641;neuron development#GO:0048666;lysosomal transport#GO:0007041;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle organization#GO:0006996;neuron projection development#GO:0031175;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;vacuole organization#GO:0007033;organelle localization#GO:0051640;dendrite morphogenesis#GO:0048813;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;intracellular transport#GO:0046907;developmental process#GO:0032502;vacuolar transport#GO:0007034;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;lytic vacuole organization#GO:0080171;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;lysosome localization#GO:0032418 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 GORGO|Ensembl=ENSGGOG00000014514.3|UniProtKB=G3RF00 G3RF00 LOC101137637 PTHR26450:SF87 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000041011.1|UniProtKB=G3RKB0 G3RKB0 H2AC8 PTHR23430:SF56 HISTONE H2A HISTONE H2A TYPE 1-D structural molecule activity#GO:0005198 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000036824.1|UniProtKB=A0A2I2Y957 A0A2I2Y957 LRRC19 PTHR31450:SF4 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 LRRC19 FAMILY MEMBER LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;signaling#GO:0023052;toll-like receptor signaling pathway#GO:0002224;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000014230.3|UniProtKB=G3S0X6 G3S0X6 KATNBL1 PTHR14682:SF1 KATNB1-LIKE PROTEIN 1 KATNB1-LIKE PROTEIN 1 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010 microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015125.3|UniProtKB=G3RGM3 G3RGM3 ROBO3 PTHR13817:SF103 TITIN HEMICENTIN 2 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000014090.3|UniProtKB=G3RDX9 G3RDX9 MAB21L2 PTHR10656:SF37 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 2 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 nucleotidyltransferase#PC00174;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000011840.3|UniProtKB=A0A2I2YCI2 A0A2I2YCI2 TBP PTHR10126:SF42 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription#GO:0006351;gene expression#GO:0010467;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;Huntington disease#P00029>TBP#P00779 GORGO|Ensembl=ENSGGOG00000011694.3|UniProtKB=G3R7Q8 G3R7Q8 SSNA1 PTHR28661:SF3 SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1 MICROTUBULE NUCLEATION FACTOR SSNA1 axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;developmental growth#GO:0048589;cellular developmental process#GO:0048869;developmental cell growth#GO:0048588;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;axon extension#GO:0048675;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cell growth#GO:0016049;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;neuron projection extension#GO:1990138;axonogenesis#GO:0007409;developmental growth involved in morphogenesis#GO:0060560 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;axon#GO:0030424;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000009333.3|UniProtKB=G3R1N7 G3R1N7 CCDC137 PTHR21838:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000000170.3|UniProtKB=G3RSH3 G3RSH3 CD46 PTHR19325:SF521 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING MEMBRANE COFACTOR PROTEIN regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;T cell mediated immunity#GO:0002456;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;regulation of immune effector process#GO:0002697;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune response#GO:0006955;adaptive immune response#GO:0002250;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;complement component#PC00078 GORGO|Ensembl=ENSGGOG00000005305.3|UniProtKB=G3QRE7 G3QRE7 PAFAH1B1 PTHR44129:SF16 WD REPEAT-CONTAINING PROTEIN POP1 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cell migration#GO:0016477;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;axo-dendritic transport#GO:0008088;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;multicellular organism development#GO:0007275;neuron migration#GO:0001764;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;developmental process#GO:0032502;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell differentiation#GO:0030154;cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;axonal transport#GO:0098930;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;generation of neurons#GO:0048699 membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000010630.3|UniProtKB=G3SB08 G3SB08 EML4 PTHR13720:SF11 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 4 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000006736.3|UniProtKB=A0A2I2ZBS6 A0A2I2ZBS6 PTHR16399:SF15 GASDERMIN GASDERMIN-D phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;inflammatory response#GO:0006954;response to bacterium#GO:0009617;defense response#GO:0006952;response to external stimulus#GO:0009605 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;canonical inflammasome complex#GO:0061702;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016483.3|UniProtKB=A0A2I2ZVT1 A0A2I2ZVT1 ZBTB1 PTHR24399:SF21 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 1 sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000044011.1|UniProtKB=A0A2I2YT26 A0A2I2YT26 PTHR10256:SF3 SELENIDE, WATER DIKINASE SELENIDE, WATER DIKINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000015202.3|UniProtKB=G3RGS5 G3RGS5 IRAK1BP1 PTHR18842:SF2 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000002597.3|UniProtKB=A0A2I2Z773 A0A2I2Z773 CGREF1 PTHR23104:SF15 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN CELL GROWTH REGULATOR WITH EF HAND DOMAIN PROTEIN 1 regulation of cellular process#GO:0050794;regulation of cell growth#GO:0001558;regulation of cellular component organization#GO:0051128;negative regulation of cell growth#GO:0030308;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;negative regulation of cellular process#GO:0048523 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013317.3|UniProtKB=G3RBX4 G3RBX4 KDSR PTHR43550:SF3 3-KETODIHYDROSPHINGOSINE REDUCTASE 3-KETODIHYDROSPHINGOSINE REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007062.3|UniProtKB=G3QVX1 G3QVX1 CFAP161 PTHR24274:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;cilium#GO:0005929 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000011542.3|UniProtKB=G3R7C3 G3R7C3 C1RL PTHR24255:SF26 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1R SUBCOMPONENT-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 primary metabolic process#GO:0044238;zymogen activation#GO:0031638;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000027915.2|UniProtKB=A0A2I2YF29 A0A2I2YF29 ALKBH7 PTHR21052:SF0 SPERMATOGENESIS ASSOCIATED 11-RELATED RNA DEMETHYLASE ALKBH7, MITOCHONDRIAL dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000012186.3|UniProtKB=G3S0P1 G3S0P1 EIF1AX PTHR21668:SF6 EIF-1A EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000005430.3|UniProtKB=G3QRQ4 G3QRQ4 PNPLA4 PTHR12406:SF48 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;transferase activity#GO:0016740;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;triacylglycerol lipase activity#GO:0004806 cellular process#GO:0009987;lipid catabolic process#GO:0016042;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;chemical homeostasis#GO:0048878;neutral lipid catabolic process#GO:0046461;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;homeostatic process#GO:0042592;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;glycerolipid catabolic process#GO:0046503;triglyceride catabolic process#GO:0019433 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000026417.2|UniProtKB=G3S6D6 G3S6D6 CADM2 PTHR45889:SF1 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 2 cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell body#GO:0044297;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000005303.3|UniProtKB=A0A2I2ZQW6 A0A2I2ZQW6 RAPGEF2 PTHR45161:SF2 CYTOSKELETON-ASSOCIATED PROTEIN 4 RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 2 GORGO|Ensembl=ENSGGOG00000014179.3|UniProtKB=G3RE62 G3RE62 DPY19L4 PTHR31488:SF2 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L4-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000001943.3|UniProtKB=G3QHT1 G3QHT1 MTMR10 PTHR10807:SF39 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 10 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 dephosphorylation#GO:0016311;lipid modification#GO:0030258;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000012463.4|UniProtKB=A0A2I2ZF55 A0A2I2ZF55 LOC101149047 PTHR24027:SF78 CADHERIN-23 CADHERIN-LIKE PROTEIN 26 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell migration#GO:0016477;cell motility#GO:0048870 extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000002875.3|UniProtKB=G3QK58 G3QK58 IGSF10 PTHR24369:SF163 ANTIGEN BSP, PUTATIVE-RELATED MATRIX-REMODELING-ASSOCIATED PROTEIN 5 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000003646.3|UniProtKB=A0A2I2ZBM4 A0A2I2ZBM4 SYBU PTHR16208:SF4 MICROTUBULE-ASSOCIATED PROTEIN/SYNTAPHILIN SYNTABULIN microtubule-based transport#GO:0099111;synapse organization#GO:0050808;axonal transport#GO:0098930;organelle localization#GO:0051640;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;localization#GO:0051179;cellular localization#GO:0051641;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;establishment of organelle localization#GO:0051656;cell junction organization#GO:0034330;microtubule-based movement#GO:0007018;developmental process#GO:0032502;transport#GO:0006810;intracellular transport#GO:0046907;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;axo-dendritic transport#GO:0008088;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;developmental maturation#GO:0021700;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881 SNARE protein#PC00034 GORGO|Ensembl=ENSGGOG00000010289.3|UniProtKB=G3R454 G3R454 CRACR2A PTHR47977:SF65 RAS-RELATED PROTEIN RAB EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 4B carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000038796.1|UniProtKB=G3S1A2 G3S1A2 PTHR23267:SF399 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000006834.3|UniProtKB=A0A2I2ZPX7 A0A2I2ZPX7 LOC101148909 PTHR12610:SF22 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000022773.2|UniProtKB=G3S0U4 G3S0U4 GTF2E1 PTHR13097:SF8 TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIEalpha#P00669;General transcription regulation#P00023>TFIIE#P00666;Transcription regulation by bZIP transcription factor#P00055>TFIIEalpha#P01398;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395 GORGO|Ensembl=ENSGGOG00000042429.1|UniProtKB=A0A2I2ZWB8 A0A2I2ZWB8 VENTX PTHR24327:SF29 HOMEOBOX PROTEIN HOMEOBOX PROTEIN VENTX sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000010533.3|UniProtKB=G3R4R3 G3R4R3 TRIM65 PTHR24103:SF569 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM65 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000043278.1|UniProtKB=A0A2I2Y8N9 A0A2I2Y8N9 LOC101148641 PTHR31107:SF2 APOPTOGENIC PROTEIN 1, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 8 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003524.3|UniProtKB=G3QLU7 G3QLU7 PTHR11210:SF2 RING BOX E3 UBIQUITIN-PROTEIN LIGASE RBX1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000034989.2|UniProtKB=A0A2I2ZHZ0 A0A2I2ZHZ0 STK3 PTHR48015:SF23 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE 3 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;hippo signaling#GO:0035329;negative regulation of signal transduction#GO:0009968;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000010572.3|UniProtKB=G3R4W0 G3R4W0 EXOSC10 PTHR12124:SF47 POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED EXOSOME COMPLEX COMPONENT 10 GORGO|Ensembl=ENSGGOG00000009016.3|UniProtKB=A0A2I2YCA5 A0A2I2YCA5 KLHDC2 PTHR46228:SF3 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000028605.2|UniProtKB=G3SK70 G3SK70 DLL4 PTHR24044:SF320 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 4 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of Notch signaling pathway#GO:0045746;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;Notch signaling pathway#GO:0007219;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Delta#P01116 GORGO|Ensembl=ENSGGOG00000028325.1|UniProtKB=G3RYU2 G3RYU2 COX2 PTHR22888:SF9 CYTOCHROME C OXIDASE, SUBUNIT II CYTOCHROME C OXIDASE SUBUNIT 2 electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle membrane#GO:0031090;transporter complex#GO:1990351;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176 Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06899;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06686;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#P06734 GORGO|Ensembl=ENSGGOG00000026739.2|UniProtKB=A0A2I2ZDS3 A0A2I2ZDS3 MAT2B PTHR10491:SF6 DTDP-4-DEHYDRORHAMNOSE REDUCTASE METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987;biosynthetic process#GO:0009058 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 reductase#PC00198 O-antigen biosynthesis#P02757>dTDP-4-dehydrorhamnose reductase#P03050 GORGO|Ensembl=ENSGGOG00000015423.3|UniProtKB=A0A2I2Y768 A0A2I2Y768 PTHR33766:SF1 PROTEIN FAM181B PROTEIN FAM181A GORGO|Ensembl=ENSGGOG00000015852.3|UniProtKB=G3RIJ3 G3RIJ3 DNAH1 PTHR46961:SF13 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN HEAVY CHAIN, CYTOPLASMIC-LIKE PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000008350.3|UniProtKB=G3SIP4 G3SIP4 FRMD7 PTHR23280:SF34 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000007596.3|UniProtKB=G3QX98 G3QX98 HEATR9 PTHR38323:SF1 PROTEIN HEATR9 PROTEIN HEATR9 GORGO|Ensembl=ENSGGOG00000001784.3|UniProtKB=G3QHD2 G3QHD2 LRRFIP2 PTHR19212:SF6 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 2 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000002806.3|UniProtKB=G3QK06 G3QK06 KRT6A PTHR45616:SF39 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 6A-RELATED structural molecule activity#GO:0005198 cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epidermis development#GO:0008544;developmental process#GO:0032502;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 GORGO|Ensembl=ENSGGOG00000022640.2|UniProtKB=A0A2I2ZIR9 A0A2I2ZIR9 RPS3A PTHR11830:SF25 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000011908.3|UniProtKB=G3R8B7 G3R8B7 C1H1orf87 PTHR34830:SF1 SIMILAR TO HYPOTHETICAL PROTEIN MGC34837 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 87 GORGO|Ensembl=ENSGGOG00000006189.3|UniProtKB=G3QTN3 G3QTN3 ZSWIM8 PTHR22619:SF1 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 8 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000010846.3|UniProtKB=G3R5J6 G3R5J6 RETREG2 PTHR20952:SF4 ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN RETICULOPHAGY REGULATOR 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;autophagy#GO:0006914;reticulophagy#GO:0061709;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macroautophagy#GO:0016236;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;endoplasmic reticulum membrane organization#GO:0090158;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;catabolic process#GO:0009056;endoplasmic reticulum tubular network organization#GO:0071786;process utilizing autophagic mechanism#GO:0061919 membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002141.3|UniProtKB=A0A2I2YDF7 A0A2I2YDF7 NUMB PTHR47368:SF5 NUMB PROTEIN NUMB HOMOLOG regulation of nervous system development#GO:0051960;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;positive regulation of nervous system development#GO:0051962;regulation of cellular process#GO:0050794;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cell development#GO:0060284;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;membrane#GO:0016020 Notch signaling pathway#P00045>Numb#P01118 GORGO|Ensembl=ENSGGOG00000014444.3|UniProtKB=G3REU1 G3REU1 PCDH18 PTHR24028:SF9 CADHERIN-87A PROTOCADHERIN-18 cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000010304.3|UniProtKB=G3R473 G3R473 ADCY1 PTHR45627:SF26 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 1 lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975 response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;CCKR signaling map#P06959>Adenylate cyclase#P07127;Gonadotropin-releasing hormone receptor pathway#P06664>AC#P06699;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760 GORGO|Ensembl=ENSGGOG00000022001.2|UniProtKB=G3RRI0 G3RRI0 PTHR11661:SF21 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11 binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010919.3|UniProtKB=G3R5R7 G3R5R7 HMGCR PTHR10572:SF24 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058 peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;membrane#GO:0016020;cytoplasm#GO:0005737;peroxisomal membrane#GO:0005778;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 reductase#PC00198 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA reductase#P00491 GORGO|Ensembl=ENSGGOG00000025210.2|UniProtKB=A0A2I2ZXE5 A0A2I2ZXE5 PTHR48013:SF29 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 non-receptor serine/threonine protein kinase#PC00167 Oxidative stress response#P00046>MKK4#P01138;Ras Pathway#P04393>MKK4/7#P04565;p38 MAPK pathway#P05918>MKK4#P06034;Huntington disease#P00029>MAPKK4#P00787;FAS signaling pathway#P00020>MKK4#P00610;CCKR signaling map#P06959>MAP2K4#P07074;EGF receptor signaling pathway#P00018>MKK4,7#P00555;FGF signaling pathway#P00021>MKK4,7#P00637;Apoptosis signaling pathway#P00006>SEK1#P00266;Integrin signalling pathway#P00034>MEK#P00925;Angiogenesis#P00005>JNKK1#P00199;Huntington disease#P00029>SEK-1#P00792 GORGO|Ensembl=ENSGGOG00000023200.2|UniProtKB=G3SIP3 G3SIP3 VAMP4 PTHR46897:SF1 VESICLE-ASSOCIATED MEMBRANE PROTEIN 4 VESICLE-ASSOCIATED MEMBRANE PROTEIN 4 biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of protein localization to membrane#GO:1905475;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport to the plasma membrane#GO:0098876;regulation of transport#GO:0051049;regulation of localization#GO:0032879;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;endocytic recycling#GO:0032456;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;SNARE complex#GO:0031201;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;presynapse#GO:0098793;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000041219.1|UniProtKB=A0A2I2Z6Z7 A0A2I2Z6Z7 PTHR13112:SF13 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN UPF3 DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;RNA binding#GO:0003723;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA catabolic process#GO:0006401;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000006713.3|UniProtKB=A0A2I2ZQD7 A0A2I2ZQD7 NELFCD PTHR12144:SF0 NEGATIVE ELONGATION FACTOR D NEGATIVE ELONGATION FACTOR C_D binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000003348.3|UniProtKB=G3QLE4 G3QLE4 CUL2 PTHR11932:SF174 CULLIN CULLIN-2 protein binding#GO:0005515;structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000014525.3|UniProtKB=G3RF17 G3RF17 PTHR28495:SF1 HYPOTHETICAL PROTEIN LOC100359752 GENE, 17266-RELATED development of primary male sexual characteristics#GO:0046546;male sex differentiation#GO:0046661;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;male gonad development#GO:0008584;multicellular organismal process#GO:0032501;gonad development#GO:0008406;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;reproductive system development#GO:0061458;system development#GO:0048731;developmental process involved in reproduction#GO:0003006;reproductive structure development#GO:0048608;reproductive process#GO:0022414 GORGO|Ensembl=ENSGGOG00000041243.1|UniProtKB=A0A2I2ZQH3 A0A2I2ZQH3 MANEA PTHR13572:SF1 ENDO-ALPHA-1,2-MANNOSIDASE GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000008456.3|UniProtKB=G3QZF8 G3QZF8 ADGRG3 PTHR12011:SF285 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G3 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000026546.2|UniProtKB=G3RZ73 G3RZ73 KLKB1 PTHR24253:SF64 TRANSMEMBRANE PROTEASE SERINE PLASMA KALLIKREIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 negative regulation of response to external stimulus#GO:0032102;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;gene expression#GO:0010467;protein maturation#GO:0051604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of response to wounding#GO:1903034;negative regulation of response to wounding#GO:1903035;metabolic process#GO:0008152;regulation of wound healing#GO:0061041;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;zymogen activation#GO:0031638;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;negative regulation of coagulation#GO:0050819;negative regulation of hemostasis#GO:1900047;proteolysis#GO:0006508;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of coagulation#GO:0050818;negative regulation of response to stimulus#GO:0048585;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;regulation of hemostasis#GO:1900046;plasminogen activation#GO:0031639;negative regulation of wound healing#GO:0061045;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;negative regulation of blood coagulation#GO:0030195;regulation of response to stress#GO:0080134;negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 Blood coagulation#P00011>Prekallikrein#P00439;Blood coagulation#P00011>Kallikrein#P00437 GORGO|Ensembl=ENSGGOG00000001259.3|UniProtKB=G3QXN7 G3QXN7 NLRP2 PTHR45690:SF14 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 2 regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000016519.3|UniProtKB=G3S624 G3S624 MAPK9 PTHR24055:SF172 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 9 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 response to stimulus#GO:0050896;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 B cell activation#P00010>Jnk#P00402;Ras Pathway#P04393>JNK#P04572;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Huntington disease#P00029>JNK-2#P00799;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;FAS signaling pathway#P00020>JNK#P00615;EGF receptor signaling pathway#P00018>JNK1-3#P00545;Integrin signalling pathway#P00034>Jnk#P00951;FGF signaling pathway#P00021>JNK1-3#P00628;TGF-beta signaling pathway#P00052>JNK#P01284;T cell activation#P00053>Jnk#P01336;Parkinson disease#P00049>SAPK#P01219;Toll receptor signaling pathway#P00054>JNK#P01375;Oxidative stress response#P00046>JNK1/2#P01129;Apoptosis signaling pathway#P00006>JNK#P00274;CCKR signaling map#P06959>MAPK8-10#P07090;Gonadotropin-releasing hormone receptor pathway#P06664>JNK1/2#P06847 GORGO|Ensembl=ENSGGOG00000009860.3|UniProtKB=A0A2I2ZNA4 A0A2I2ZNA4 ATL3 PTHR10751:SF32 GUANYLATE BINDING PROTEIN ATLASTIN-3 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cellular component organization#GO:0016043;organelle organization#GO:0006996;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 G-protein#PC00020;heterotrimeric G-protein#PC00117 GORGO|Ensembl=ENSGGOG00000027055.2|UniProtKB=A0A2I2YKI2 A0A2I2YKI2 PTHR22745:SF0 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000013174.3|UniProtKB=G3RBJ7 G3RBJ7 PRPF3 PTHR14212:SF0 U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;U4/U6 x U5 tri-snRNP complex#GO:0046540 RNA splicing factor#PC00148 mRNA splicing#P00058>U6#P01473;mRNA splicing#P00058>U4#P01476 GORGO|Ensembl=ENSGGOG00000027248.2|UniProtKB=G3SGE9 G3SGE9 BRCC3 PTHR10410:SF34 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED LYS-63-SPECIFIC DEUBIQUITINASE BRCC36 metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000004732.3|UniProtKB=G3QPX7 G3QPX7 C16H15orf61 PTHR34651:SF1 SIMILAR TO ENSANGP00000021391 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 61 GORGO|Ensembl=ENSGGOG00000042313.1|UniProtKB=A0A2I2YZP9 A0A2I2YZP9 ZNF195 PTHR24384:SF87 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 195 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000022472.2|UniProtKB=G3R6Z9 G3R6Z9 LOC109024684 PTHR11431:SF37 FERRITIN FERRITIN HEAVY CHAIN ferrous iron binding#GO:0008198;iron ion binding#GO:0005506;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 metal ion transport#GO:0030001;transition metal ion transport#GO:0000041;transport#GO:0006810;iron ion transport#GO:0006826;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000006534.3|UniProtKB=A0A2I2YME5 A0A2I2YME5 KCNIP2 PTHR23055:SF65 CALCIUM BINDING PROTEINS A-TYPE POTASSIUM CHANNEL MODULATORY PROTEIN KCNIP2 ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;calcium ion binding#GO:0005509;potassium channel regulator activity#GO:0015459;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;channel regulator activity#GO:0016247;metal ion binding#GO:0046872 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000010993.3|UniProtKB=G3R5Y2 G3R5Y2 PCK1 PTHR11561:SF18 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP] ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;lyase activity#GO:0016829;metal ion binding#GO:0046872;cation binding#GO:0043169;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 response to endogenous stimulus#GO:0009719;response to hexose#GO:0009746;carboxylic acid metabolic process#GO:0019752;carbohydrate homeostasis#GO:0033500;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;intracellular glucose homeostasis#GO:0001678;response to hormone#GO:0009725;response to stress#GO:0006950;gluconeogenesis#GO:0006094;response to chemical#GO:0042221;response to lipid#GO:0033993;metabolic process#GO:0008152;cellular response to glucose stimulus#GO:0071333;monosaccharide metabolic process#GO:0005996;chemical homeostasis#GO:0048878;glucose metabolic process#GO:0006006;animal organ development#GO:0048513;response to starvation#GO:0042594;hexose biosynthetic process#GO:0019319;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;cellular response to peptide hormone stimulus#GO:0071375;response to nitrogen compound#GO:1901698;system development#GO:0048731;response to nutrient levels#GO:0031667;cellular response to nitrogen compound#GO:1901699;tissue development#GO:0009888;developmental process#GO:0032502;small molecule biosynthetic process#GO:0044283;cellular developmental process#GO:0048869;intracellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;liver development#GO:0001889;cellular response to chemical stimulus#GO:0070887;response to monosaccharide#GO:0034284;animal gross anatomical part developmental process#GO:0160108;response to carbohydrate#GO:0009743;cellular response to oxygen-containing compound#GO:1901701;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;cellular response to lipid#GO:0071396;carbohydrate biosynthetic process#GO:0016051;alcohol metabolic process#GO:0006066;multicellular organism development#GO:0007275;cellular response to steroid hormone stimulus#GO:0071383;glucose homeostasis#GO:0042593;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to steroid hormone#GO:0048545;anatomical structure development#GO:0048856;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;response to glucose#GO:0009749;epithelial cell differentiation#GO:0030855;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;response to peptide hormone#GO:0043434;cellular response to insulin stimulus#GO:0032869;cellular homeostasis#GO:0019725 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 Pyruvate metabolism#P02772>Phosphoenolpyruvate Carboxykinase#P03135 GORGO|Ensembl=ENSGGOG00000004213.3|UniProtKB=G3QNL3 G3QNL3 PAX7 PTHR45636:SF26 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-7 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000010230.3|UniProtKB=G3S0A6 G3S0A6 DNAJC7 PTHR44200:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000007518.3|UniProtKB=G3QX26 G3QX26 ISCA1 PTHR10072:SF65 IRON-SULFUR CLUSTER ASSEMBLY PROTEIN IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;iron-sulfur cluster assembly#GO:0016226;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000016238.3|UniProtKB=G3RJF6 G3RJF6 HELB PTHR43788:SF19 DNA2/NAM7 HELICASE FAMILY MEMBER DNA HELICASE B ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543 negative regulation of double-strand break repair via homologous recombination#GO:2000042;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cellular response to stress#GO:0080135;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;regulation of DNA recombination#GO:0000018;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of double-strand break repair#GO:2000779;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;negative regulation of DNA recombination#GO:0045910;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000006612.3|UniProtKB=G3QUQ8 G3QUQ8 LOC101146453 PTHR26450:SF168 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000207.3|UniProtKB=G3QD93 G3QD93 DOK2 PTHR21258:SF14 DOCKING PROTEIN RELATED DOCKING PROTEIN 2 receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515;signaling adaptor activity#GO:0035591 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dok-R#P00180 GORGO|Ensembl=ENSGGOG00000025318.2|UniProtKB=G3RZS1 G3RZS1 SLC2A1 PTHR23503:SF51 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 import across plasma membrane#GO:0098739;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;carbohydrate transport#GO:0008643;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#G06890;Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#P06724;Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#G06675 GORGO|Ensembl=ENSGGOG00000038999.1|UniProtKB=A0A2I2ZYF8 A0A2I2ZYF8 CALN1 PTHR46311:SF3 CALCIUM-BINDING PROTEIN 8-RELATED CALCIUM-BINDING PROTEIN 8 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;cellular anatomical structure#GO:0110165;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000011657.3|UniProtKB=G3R7M8 G3R7M8 SLC30A3 PTHR11562:SF30 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A3-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915 metal ion transport#GO:0030001;response to stimulus#GO:0050896;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;response to chemical#GO:0042221;response to metal ion#GO:0010038;transport#GO:0006810;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003419.3|UniProtKB=G3RQN6 G3RQN6 SNX10 PTHR46209:SF2 PX DOMAIN-CONTAINING PROTEIN SORTING NEXIN-10 binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;vesicle organization#GO:0016050;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000010753.3|UniProtKB=G3R5C1 G3R5C1 STAC3 PTHR15135:SF2 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN 3 ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 nervous system process#GO:0050877;neuromuscular process#GO:0050905;regulation of protein localization#GO:0032880;muscle system process#GO:0003012;regulation of biological process#GO:0050789;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794;muscle contraction#GO:0006936;regulation of localization#GO:0032879;system process#GO:0003008;positive regulation of cellular process#GO:0048522;regulation of protein localization to membrane#GO:1905475;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898 GORGO|Ensembl=ENSGGOG00000008836.3|UniProtKB=G3S3G4 G3S3G4 LMNTD1 PTHR47012:SF1 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 1 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 1 nucleus#GO:0005634;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000004790.3|UniProtKB=G3QQ35 G3QQ35 TTPAL PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000004794.3|UniProtKB=G3QQ36 G3QQ36 C9H11orf68 PTHR31977:SF1 UPF0696 PROTEIN C11ORF68 UPF0696 PROTEIN C11ORF68 GORGO|Ensembl=ENSGGOG00000002944.3|UniProtKB=G3QKC3 G3QKC3 CLBA1 PTHR16156:SF7 AFTIPHILIN A-RELATED CLATHRIN BINDING BOX OF AFTIPHILIN CONTAINING 1 binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515 endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;vesicle coat#GO:0030120;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;trans-Golgi network membrane#GO:0032588;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;coated membrane#GO:0048475;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000042712.1|UniProtKB=A0A2I2ZUI7 A0A2I2ZUI7 LOC101136323 PTHR26450:SF92 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51E2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008415.3|UniProtKB=G3QZB6 G3QZB6 TIMM17A PTHR10485:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transmembrane protein transporter activity#GO:0008320 mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;mitochondrial transmembrane transport#GO:1990542 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040465.1|UniProtKB=A0A2I2ZFP1 A0A2I2ZFP1 PTHR40387:SF1 PROTEIN FAM240B PROTEIN FAM240B GORGO|Ensembl=ENSGGOG00000009507.2|UniProtKB=G3R246 G3R246 RAB9B PTHR47981:SF17 RAB FAMILY RAS-RELATED PROTEIN RAB-9B molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;cytosolic transport#GO:0016482;endocytosis#GO:0006897;organelle assembly#GO:0070925;vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040;membrane fusion#GO:0061025;retrograde transport, endosome to Golgi#GO:0042147;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;lytic vacuole organization#GO:0080171;transport#GO:0006810;phagolysosome assembly#GO:0001845;phagocytosis#GO:0006909;intracellular transport#GO:0046907;endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234 intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505;late endosome#GO:0005770;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000025608.2|UniProtKB=G3RNI6 G3RNI6 AKAP6 PTHR14514:SF2 PKA ANCHORING PROTEIN A-KINASE ANCHOR PROTEIN 6 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of muscle system process#GO:0090257;regulation of transmembrane transport#GO:0034762;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of membrane potential#GO:0042391;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of monoatomic ion transport#GO:0043269 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;nucleus#GO:0005634;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000003035.3|UniProtKB=G3QKK8 G3QKK8 LOC101128282 PTHR26453:SF700 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10J5 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005019.3|UniProtKB=G3QQP6 G3QQP6 CERCAM PTHR10730:SF9 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER INACTIVE GLYCOSYLTRANSFERASE 25 FAMILY MEMBER 3 glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016735.3|UniProtKB=G3RKP8 G3RKP8 CIMIP6 PTHR35087:SF1 SIMILAR TO HYPOTHETICAL PROTEIN FLJ40298 CILIARY MICROTUBULE INNER PROTEIN 6 GORGO|Ensembl=ENSGGOG00000024417.2|UniProtKB=A0A2I2YXQ7 A0A2I2YXQ7 LOC101142312 PTHR11758:SF13 40S RIBOSOMAL PROTEIN S15A SMALL RIBOSOMAL SUBUNIT PROTEIN US8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010418.3|UniProtKB=G3R4G9 G3R4G9 MAP3K9 PTHR44329:SF35 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 GORGO|Ensembl=ENSGGOG00000024314.2|UniProtKB=A0A2I2ZWJ3 A0A2I2ZWJ3 PTHR10806:SF42 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11B-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000041540.1|UniProtKB=A0A2I2Z2X3 A0A2I2Z2X3 PTHR10732:SF9 40S RIBOSOMAL PROTEIN S17 40S RIBOSOMAL PROTEIN S17 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007527.3|UniProtKB=G3QX35 G3QX35 RWDD2B PTHR15955:SF8 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2B ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000013224.2|UniProtKB=G3RBN9 G3RBN9 PELI3 PTHR12098:SF9 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 3 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004098.3|UniProtKB=G3QNB1 G3QNB1 LOC101143588 PTHR33528:SF14 OS07G0239500 PROTEIN SOLUTE CARRIER FAMILY 35 MEMBER A4 GORGO|Ensembl=ENSGGOG00000025286.2|UniProtKB=A0A2I2Y2G2 A0A2I2Y2G2 PTHR11143:SF11 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL24 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000027819.2|UniProtKB=G3SDX3 G3SDX3 GAS1 PTHR16840:SF3 GROWTH ARREST-SPECIFIC PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 1 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000037174.1|UniProtKB=A0A2I2YL07 A0A2I2YL07 PTHR23268:SF115 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 10-3 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000027492.2|UniProtKB=G3S9M7 G3S9M7 MRPL32 PTHR21026:SF2 39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011368.3|UniProtKB=G3R6W7 G3R6W7 DNAI7 PTHR20929:SF11 LUNG ADENOMA SUSCEPTIBILITY 1-RELATED DYNEIN AXONEMAL INTERMEDIATE CHAIN 7 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000037624.1|UniProtKB=A0A2I2YYH6 A0A2I2YYH6 IGLC3 PTHR23266:SF283 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 2-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000013384.3|UniProtKB=A0A2I2ZC31 A0A2I2ZC31 SLC6A6 PTHR11616:SF141 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT TAURINE TRANSPORTER solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000004087.3|UniProtKB=A0A2I2ZL94 A0A2I2ZL94 EMC3 PTHR13116:SF10 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641 membrane protein complex#GO:0098796;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;EMC complex#GO:0072546;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000009500.3|UniProtKB=A0A2I2Z650 A0A2I2Z650 ZDHHC23 PTHR22883:SF475 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC23 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;protein targeting to membrane#GO:0006612;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to plasma membrane#GO:0072659;protein targeting#GO:0006605 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023368.2|UniProtKB=A0A2I2Y3H7 A0A2I2Y3H7 ABCC9 PTHR24223:SF173 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000007300.3|UniProtKB=G3QWJ1 G3QWJ1 ATXN7L2 PTHR15117:SF5 ATAXIN 7 RELATED ATAXIN-7-LIKE PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 GORGO|Ensembl=ENSGGOG00000034891.2|UniProtKB=G3SKG4 G3SKG4 DLGAP1 PTHR12353:SF7 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 1 regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051 glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell junction#GO:0030054;postsynaptic specialization#GO:0099572;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026387.2|UniProtKB=G3S287 G3S287 PTHR11360:SF258 MONOCARBOXYLATE TRANSPORTER SOLUTE CARRIER FAMILY 16 MEMBER 6 monocarboxylic acid transmembrane transporter activity#GO:0008028;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016748.3|UniProtKB=G3RKR7 G3RKR7 SPOCD1 PTHR11477:SF18 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN SPOC DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component assembly#GO:0022607;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;constitutive heterochromatin formation#GO:0140719;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulatory ncRNA-mediated heterochromatin formation#GO:0031048 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000027928.2|UniProtKB=G3RQC4 G3RQC4 GXYLT1 PTHR46012:SF3 IP22168P GLUCOSIDE XYLOSYLTRANSFERASE 1 xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 GORGO|Ensembl=ENSGGOG00000009105.3|UniProtKB=G3R150 G3R150 LOC101143888 PTHR24286:SF100 CYTOCHROME P450 26 CYTOCHROME P450 26C1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 oxoacid metabolic process#GO:0043436;animal gross anatomical part developmental process#GO:0160108;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological quality#GO:0065008;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;central nervous system development#GO:0007417;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;developmental process#GO:0032502;lipid metabolic process#GO:0006629;multicellular organism development#GO:0007275;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;hormone metabolic process#GO:0042445;monocarboxylic acid catabolic process#GO:0072329;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000038733.1|UniProtKB=G3QMA7 G3QMA7 ISY1 PTHR13021:SF8 PRE-MRNA-SPLICING FACTOR ISY1 PRE-MRNA-SPLICING FACTOR ISY1 HOMOLOG RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000007913.3|UniProtKB=G3QY20 G3QY20 SGTA PTHR45831:SF3 LD24721P SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN ALPHA protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;protein targeting to ER#GO:0045047;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;establishment of protein localization to endoplasmic reticulum#GO:0072599 membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010591.3|UniProtKB=G3R4X1 G3R4X1 TF PTHR11485:SF31 TRANSFERRIN SEROTRANSFERRIN defense response#GO:0006952;response to external stimulus#GO:0009605;antibacterial humoral response#GO:0019731;establishment of localization#GO:0051234;transport#GO:0006810;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;metal ion transport#GO:0030001;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;recycling endosome#GO:0055037 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000012834.3|UniProtKB=A0A2I2YER9 A0A2I2YER9 DCTN5 PTHR46126:SF2 DYNACTIN SUBUNIT 5 DYNACTIN SUBUNIT 5 actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000016102.3|UniProtKB=G3RJ35 G3RJ35 LOC101152910 PTHR11876:SF6 ALPHA-DEFENSIN 1 DEFENSIN ALPHA 5 response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000008518.3|UniProtKB=G3QZM0 G3QZM0 CFAP251 PTHR13720:SF60 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 251 cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000011983.3|UniProtKB=A0A2I2ZCX8 A0A2I2ZCX8 PUM1 PTHR12537:SF1 RNA BINDING PROTEIN PUMILIO-RELATED PUMILIO HOMOLOG 1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000023919.3|UniProtKB=G3SED0 G3SED0 UBP1 PTHR11037:SF13 TRANSCRIPTION FACTOR CP2 UPSTREAM-BINDING PROTEIN 1 transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004458.3|UniProtKB=G3QP84 G3QP84 PSMD8 PTHR12387:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;proteasome complex#GO:0000502;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003367.3|UniProtKB=A0A2I2YB28 A0A2I2YB28 MYCBPAP PTHR12276:SF123 EPSIN/ENT-RELATED MYCBP-ASSOCIATED PROTEIN clathrin binding#GO:0030276;phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289;protein binding#GO:0005515 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000043020.1|UniProtKB=A0A2I2ZC70 A0A2I2ZC70 PTHR12889:SF1 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;cell communication#GO:0007154;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;signal transduction#GO:0007165;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>Aph-1#P00091;Notch signaling pathway#P00045>Aph-1#P01109;Alzheimer disease-presenilin pathway#P00004>Aph-1#P00170 GORGO|Ensembl=ENSGGOG00000042735.1|UniProtKB=A0A2I2YPD8 A0A2I2YPD8 PTHR23267:SF369 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000001818.3|UniProtKB=G3QHG6 G3QHG6 MRC2 PTHR22803:SF69 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED C-TYPE MANNOSE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000013039.3|UniProtKB=G3RSR8 G3RSR8 HP PTHR24256:SF524 TRYPTASE-RELATED HAPTOGLOBIN ISOFORM X1 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000015486.3|UniProtKB=G3RHJ3 G3RHJ3 ATP2C2 PTHR42861:SF23 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 2 primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000001788.3|UniProtKB=G3QHD8 G3QHD8 PTHR19376:SF11 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1 macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription by RNA polymerase I#GO:0006360;rRNA transcription#GO:0009303;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000022383.2|UniProtKB=G3SKB0 G3SKB0 PTHR46643:SF1 HOMEOBOX PROTEIN GOOSECOID-RELATED HOMEOBOX PROTEIN GOOSECOID-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015374.3|UniProtKB=G3RH83 G3RH83 BICD2 PTHR31233:SF7 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D HOMOLOG 2 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;microtubule-based movement#GO:0007018;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;macromolecule localization#GO:0033036;organelle organization#GO:0006996;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;protein localization to Golgi apparatus#GO:0034067;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;microtubule anchoring#GO:0034453;establishment of localization#GO:0051234;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000012679.3|UniProtKB=G3RAA5 G3RAA5 LOC101133172 PTHR24300:SF291 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2W1 binding#GO:0005488;tetrapyrrole binding#GO:0046906;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000037801.1|UniProtKB=A0A2I2ZM88 A0A2I2ZM88 PTHR46185:SF1 GLUTAREDOXIN-1 GLUTAREDOXIN-1 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000564.3|UniProtKB=G3SBB6 G3SBB6 PGLYRP2 PTHR11022:SF66 PEPTIDOGLYCAN RECOGNITION PROTEIN N-ACETYLMURAMOYL-L-ALANINE AMIDASE peptidoglycan muralytic activity#GO:0061783;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;pattern recognition receptor activity#GO:0038187;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023 defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000040370.1|UniProtKB=A0A2I2ZSI0 A0A2I2ZSI0 ERVV-2 PTHR10424:SF74 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRUS GROUP V MEMBER 2 ENV POLYPROTEIN cell differentiation#GO:0030154;muscle structure development#GO:0061061;myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000000677.3|UniProtKB=G3QEH2 G3QEH2 KLHDC10 PTHR46428:SF1 KELCH DOMAIN-CONTAINING PROTEIN 10 KELCH DOMAIN-CONTAINING PROTEIN 10 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stress#GO:0080134;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135 GORGO|Ensembl=ENSGGOG00000012651.3|UniProtKB=G3RPR6 G3RPR6 PKP1 PTHR10372:SF3 PLAKOPHILLIN-RELATED PLAKOPHILIN-1 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 intracellular organelle#GO:0043229;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 intermediate filament#PC00129;cytoskeletal protein#PC00085;intermediate filament binding protein#PC00130 GORGO|Ensembl=ENSGGOG00000014854.3|UniProtKB=G3RFV8 G3RFV8 ZNF583 PTHR24377:SF863 IP01015P-RELATED ZINC FINGER PROTEIN 583 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010789.3|UniProtKB=G3R5E5 G3R5E5 RPLP2 PTHR21141:SF120 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN P2 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000599.3|UniProtKB=G3QE98 G3QE98 UBASH3B PTHR16469:SF29 UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING PROTEIN B protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;regulation of bone resorption#GO:0045124;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of myeloid cell differentiation#GO:0045637;wound healing#GO:0042060;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;signal transduction#GO:0007165;coagulation#GO:0050817;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;platelet aggregation#GO:0070527;cell surface receptor signaling pathway#GO:0007166;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of release of sequestered calcium ion into cytosol#GO:0051279;cellular response to stimulus#GO:0051716;negative regulation of multicellular organismal process#GO:0051241;hemostasis#GO:0007599;regulation of transmembrane transport#GO:0034762;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell activation#GO:0001775;regulation of tissue remodeling#GO:0034103;cell communication#GO:0007154;regulation of hemopoiesis#GO:1903706;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell development#GO:0060284;regulation of bone remodeling#GO:0046850;response to wounding#GO:0009611;regulation of calcium ion transport#GO:0051924;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;homotypic cell-cell adhesion#GO:0034109;regulation of monoatomic ion transport#GO:0043269;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;regulation of monoatomic cation transmembrane transport#GO:1904062;negative regulation of cellular process#GO:0048523;blood coagulation#GO:0007596;platelet activation#GO:0030168 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000006794.3|UniProtKB=G3QV89 G3QV89 FTSJ3 PTHR10920:SF13 RIBOSOMAL RNA METHYLTRANSFERASE PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3 rRNA (guanine) methyltransferase activity#GO:0016435;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;O-methyltransferase activity#GO:0008171 macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;rRNA modification#GO:0000154;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;methylation#GO:0032259;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000043133.1|UniProtKB=A0A2I2YJX0 A0A2I2YJX0 PTHR31925:SF1 TRANSMEMBRANE PROTEIN 251 LYSOSOMAL ENZYME TRAFFICKING FACTOR GORGO|Ensembl=ENSGGOG00000041701.1|UniProtKB=A0A2I2YI43 A0A2I2YI43 PTHR31777:SF0 TRANSMEMBRANE PROTEIN 169 TRANSMEMBRANE PROTEIN 169 GORGO|Ensembl=ENSGGOG00000007801.3|UniProtKB=G3QXS9 G3QXS9 MAN1A1 PTHR11742:SF31 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IA hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000043155.1|UniProtKB=A0A2I2YU56 A0A2I2YU56 PTHR23268:SF95 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 5-4 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014130.3|UniProtKB=G3RE19 G3RE19 SHB PTHR15127:SF31 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN B binding#GO:0005488;protein binding#GO:0005515 GORGO|Ensembl=ENSGGOG00000015302.3|UniProtKB=G3RH12 G3RH12 GM2A PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;ceramide metabolic process#GO:0006672;localization#GO:0051179;lipid localization#GO:0010876;lipid transport#GO:0006869;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000006013.3|UniProtKB=G3QT74 G3QT74 OLFM2 PTHR23192:SF27 OLFACTOMEDIN-RELATED NOELIN-2 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000010522.3|UniProtKB=G3R4Q7 G3R4Q7 CRISP1 PTHR10334:SF213 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000036547.1|UniProtKB=A0A2I2ZJ46 A0A2I2ZJ46 PTHR19433:SF136 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 27 response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000037816.1|UniProtKB=A0A2I2ZIQ4 A0A2I2ZIQ4 PRR15L PTHR14581:SF5 FAMILY NOT NAMED PROLINE-RICH PROTEIN 15-LIKE PROTEIN GORGO|Ensembl=ENSGGOG00000026153.2|UniProtKB=A0A2I2YQG4 A0A2I2YQG4 PTHR11880:SF28 RIBOSOMAL PROTEIN S19P FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US19 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006165.4|UniProtKB=G3QTK1 G3QTK1 CD38 PTHR10912:SF5 ADP-RIBOSYL CYCLASE ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE 1 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of B cell proliferation#GO:0030890;regulation of lymphocyte activation#GO:0051249;positive regulation of lymphocyte proliferation#GO:0050671;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;regulation of B cell activation#GO:0050864;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of lymphocyte proliferation#GO:0050670;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte proliferation#GO:0070665;regulation of B cell proliferation#GO:0030888;positive regulation of leukocyte activation#GO:0002696;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cyclase#PC00079;metabolite interconversion enzyme#PC00262 CCKR signaling map#P06959>CD38#P07204 GORGO|Ensembl=ENSGGOG00000009921.3|UniProtKB=A0A2I2YKN9 A0A2I2YKN9 SRP14 PTHR12013:SF2 SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN SRP-dependent cotranslational protein targeting to membrane#GO:0006614;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization to endoplasmic reticulum#GO:0072599;localization within membrane#GO:0051668;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein targeting#GO:0006605 signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013599.3|UniProtKB=G3RCM9 G3RCM9 ROM1 PTHR19282:SF234 TETRASPANIN ROD OUTER SEGMENT MEMBRANE PROTEIN 1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011472.3|UniProtKB=G3R756 G3R756 PSMB6 PTHR11599:SF46 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-6 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009799.3|UniProtKB=A0A2I2Z9T8 A0A2I2Z9T8 COL11A2 PTHR24023:SF509 COLLAGEN ALPHA COLLAGEN ALPHA-2(XI) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;connective tissue development#GO:0061448;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;skeletal system development#GO:0001501;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;external encapsulating structure organization#GO:0045229;system development#GO:0048731;cartilage development#GO:0051216;cellular component organization#GO:0016043;sensory perception of sound#GO:0007605 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000009959.3|UniProtKB=G3R395 G3R395 ZNF121 PTHR24381:SF149 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 266 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024917.2|UniProtKB=A0A2I2YW61 A0A2I2YW61 PTHR23073:SF85 26S PROTEASOME REGULATORY SUBUNIT AAA+ ATPASE DOMAIN-CONTAINING PROTEIN ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502 protease#PC00190 GORGO|Ensembl=ENSGGOG00000005877.3|UniProtKB=G3QSV3 G3QSV3 SLC51A PTHR23423:SF11 ORGANIC SOLUTE TRANSPORTER-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT ALPHA transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;lipid transport#GO:0006869;macromolecule localization#GO:0033036 endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004349.3|UniProtKB=G3QNY7 G3QNY7 ING3 PTHR10333:SF114 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone H3 reader activity#GO:0140006;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;nucleus#GO:0005634;chromatin#GO:0000785;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000009968.3|UniProtKB=G3R3A6 G3R3A6 EFNB1 PTHR11304:SF17 EPHRIN EPHRIN-B1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 Angiogenesis#P00005>Eph#P00239 GORGO|Ensembl=ENSGGOG00000041481.1|UniProtKB=A0A2I2YAH5 A0A2I2YAH5 PTHR10562:SF131 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 2-RELATED protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899 post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 p53 pathway#P00059>Sumo-1 ligase#P04635 GORGO|Ensembl=ENSGGOG00000036544.1|UniProtKB=A0A2I2ZIA8 A0A2I2ZIA8 SUPT7L PTHR28598:SF1 STAGA COMPLEX 65 SUBUNIT GAMMA STAGA COMPLEX 65 SUBUNIT GAMMA transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 GORGO|Ensembl=ENSGGOG00000017001.3|UniProtKB=A0A2I2ZP89 A0A2I2ZP89 GIT1 PTHR46097:SF1 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT1 enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;molecular function activator activity#GO:0140677 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure development#GO:0048856;cellular localization#GO:0051641;localization#GO:0051179;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;nervous system development#GO:0007399;head development#GO:0060322;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;multicellular organismal process#GO:0032501;brain development#GO:0007420;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of small GTPase mediated signal transduction#GO:0051056;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;animal organ development#GO:0048513;multicellular organism development#GO:0007275;synaptic vesicle cycle#GO:0099504;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;transport#GO:0006810;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;neuron projection#GO:0043005;postsynapse#GO:0098794;cytosol#GO:0005829;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202 GORGO|Ensembl=ENSGGOG00000037157.1|UniProtKB=A0A2I2YWW1 A0A2I2YWW1 TRBV28 PTHR23268:SF121 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 28 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000006683.3|UniProtKB=G3QUY8 G3QUY8 ABTB3 PTHR46071:SF1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT- AND BTB_POZ DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014459.3|UniProtKB=G3REX3 G3REX3 RBM6 PTHR13948:SF22 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 6 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000022169.2|UniProtKB=A0A2I2YFA4 A0A2I2YFA4 PTHR10553:SF26 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;U2 snRNP#GO:0005686;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;P granule#GO:0043186;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;SMN-Sm protein complex#GO:0034719;nucleus#GO:0005634;U1 snRNP#GO:0005685;ribonucleoprotein granule#GO:0035770;catalytic step 2 spliceosome#GO:0071013;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;U12-type spliceosomal complex#GO:0005689;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type prespliceosome#GO:0071004;precatalytic spliceosome#GO:0071011;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000016810.3|UniProtKB=G3SAH7 G3SAH7 ANO9 PTHR12308:SF37 ANOCTAMIN ANOCTAMIN-9 transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010008.3|UniProtKB=G3R3E5 G3R3E5 TPRA1 PTHR15876:SF8 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000010869.3|UniProtKB=G3R5L7 G3R5L7 MLX PTHR15741:SF25 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MAX-LIKE PROTEIN X sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004737.3|UniProtKB=A0A2I2YTW4 A0A2I2YTW4 SREK1 PTHR32343:SF71 SERINE/ARGININE-RICH SPLICING FACTOR SPLICING REGULATORY GLUTAMINE_LYSINE-RICH PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000022919.2|UniProtKB=A0A2I2YHI7 A0A2I2YHI7 PTHR36683:SF1 CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1 CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1 cellular process#GO:0009987;head development#GO:0060322;nervous system development#GO:0007399;cell migration#GO:0016477;multicellular organismal process#GO:0032501;brain development#GO:0007420;developmental maturation#GO:0021700;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;anatomical structure formation involved in morphogenesis#GO:0048646;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;anatomical structure maturation#GO:0071695;cell motility#GO:0048870;cell differentiation#GO:0030154;central nervous system development#GO:0007417;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856 GORGO|Ensembl=ENSGGOG00000004671.3|UniProtKB=G3QPS6 G3QPS6 PTHR12176:SF78 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003127.3|UniProtKB=G3QKT8 G3QKT8 RTP2 PTHR14402:SF18 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 2 signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 detection of chemical stimulus involved in sensory perception#GO:0050907;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;localization within membrane#GO:0051668;sensory perception#GO:0007600;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;protein targeting#GO:0006605;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;protein targeting to membrane#GO:0006612;establishment of localization#GO:0051234;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;intracellular protein localization#GO:0008104;detection of stimulus#GO:0051606;macromolecule localization#GO:0033036;detection of stimulus involved in sensory perception#GO:0050906;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012282.3|UniProtKB=A0A2I2YA26 A0A2I2YA26 MON1A PTHR13027:SF14 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG A enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 export from cell#GO:0140352;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;macromolecule localization#GO:0033036;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;protein secretion#GO:0009306;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000007027.3|UniProtKB=G3QVU0 G3QVU0 RAB11FIP1 PTHR15746:SF22 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 1 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;regulated exocytosis#GO:0045055;transport#GO:0006810;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000016104.3|UniProtKB=G3RJ40 G3RJ40 PROC PTHR24278:SF0 COAGULATION FACTOR VITAMIN K-DEPENDENT PROTEIN C hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>PC#P00426;Blood coagulation#P00011>APC#P00423 GORGO|Ensembl=ENSGGOG00000000365.3|UniProtKB=G3QDN4 G3QDN4 RAD51D PTHR46457:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;four-way junction DNA binding#GO:0000400;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;telomere organization#GO:0032200;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;homologous recombination#GO:0035825;reproductive process#GO:0022414;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;replication fork#GO:0005657;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000014063.3|UniProtKB=G3RDV8 G3RDV8 TCP1 PTHR11353:SF192 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 protein folding chaperone complex#GO:0101031;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000016926.3|UniProtKB=G3RL83 G3RL83 CLU PTHR10970:SF1 CLUSTERIN CLUSTERIN protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of apoptotic process#GO:0042981;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of programmed cell death#GO:0043067;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 CCKR signaling map#P06959>CLU#P07069;CCKR signaling map#P06959>CLU#G07284;CCKR signaling map#P06959>CLU#G06991 GORGO|Ensembl=ENSGGOG00000002154.3|UniProtKB=A0A2I2Z873 A0A2I2Z873 RPS6KC1 PTHR15508:SF2 RIBOSOMAL PROTEIN S6 KINASE INACTIVE RIBOSOMAL PROTEIN S6 KINASE DELTA-1 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142 GORGO|Ensembl=ENSGGOG00000011094.3|UniProtKB=G3R695 G3R695 SDK2 PTHR13817:SF59 TITIN PROTEIN SIDEKICK-2 cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;synapse assembly#GO:0007416;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;synapse organization#GO:0050808 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000034996.2|UniProtKB=A0A2I2YDB8 A0A2I2YDB8 GRM7 PTHR24060:SF98 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 7 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 GORGO|Ensembl=ENSGGOG00000006455.3|UniProtKB=G3QUC2 G3QUC2 DSCAML1 PTHR13817:SF54 TITIN CELL ADHESION MOLECULE DSCAML1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000041817.1|UniProtKB=A0A2I2ZWB6 A0A2I2ZWB6 PTHR12682:SF12 ARCHEASE TRNA-SPLICING LIGASE-ACTIVATING FACTOR ARCHEASE intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000025732.2|UniProtKB=G3SEF9 G3SEF9 SPMIP7 PTHR34759:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 48 PROTEIN SPMIP7 gamete generation#GO:0007276;male gamete generation#GO:0048232;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953 GORGO|Ensembl=ENSGGOG00000001459.4|UniProtKB=G3QGI6 G3QGI6 PARP8 PTHR21328:SF3 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP8 molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;transferase activity#GO:0016740;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;pentosyltransferase activity#GO:0016763;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;glycosyltransferase activity#GO:0016757;protein kinase activator activity#GO:0030295;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165 endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;nucleus#GO:0005634;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967 GORGO|Ensembl=ENSGGOG00000001338.3|UniProtKB=G3QG71 G3QG71 TBX19 PTHR11267:SF114 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX19 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cell fate specification#GO:0001708;anatomical structure formation involved in morphogenesis#GO:0048646;animal organ development#GO:0048513;mesoderm development#GO:0007498;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular process#GO:0009987;embryo development#GO:0009790;heart development#GO:0007507;formation of primary germ layer#GO:0001704;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;gastrulation#GO:0007369;cell differentiation#GO:0030154;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;mesoderm formation#GO:0001707;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;mesoderm morphogenesis#GO:0048332;heart morphogenesis#GO:0003007;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 GORGO|Ensembl=ENSGGOG00000007957.3|UniProtKB=G3S6H7 G3S6H7 PTRH2 PTHR12649:SF31 PEPTIDYL-TRNA HYDROLASE 2 PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;hydrolase activity#GO:0016787 positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of apoptotic process#GO:0043065;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000010228.3|UniProtKB=G3R3Z8 G3R3Z8 ASS1 PTHR11587:SF5 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;ligase#PC00142 Arginine biosynthesis#P02728>Argininosuccinate synthase#P02840 GORGO|Ensembl=ENSGGOG00000009289.3|UniProtKB=A0A2I2Y3T8 A0A2I2Y3T8 MED12 PTHR46007:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000015905.3|UniProtKB=G3RIL0 G3RIL0 PHF7 PTHR12420:SF47 PHD FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE PHF7 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000003430.4|UniProtKB=G3QLL5 G3QLL5 TK2 PTHR10513:SF24 DEOXYNUCLEOSIDE KINASE THYMIDINE KINASE 2, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;deoxynucleoside kinase activity#GO:0019136 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000005879.3|UniProtKB=A0A2I2ZBT4 A0A2I2ZBT4 EVL PTHR11202:SF4 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER ENA_VASP-LIKE PROTEIN binding#GO:0005488;protein binding#GO:0005515 actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of supramolecular fiber organization#GO:1902903;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;system development#GO:0048731;actin filament-based process#GO:0030029;multicellular organismal process#GO:0032501;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;axon guidance#GO:0007411;axon development#GO:0061564;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular component size#GO:0032535;positive regulation of organelle organization#GO:0010638;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;generation of neurons#GO:0048699;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cytoskeleton organization#GO:0007010;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;regulation of anatomical structure size#GO:0090066;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182 anchoring junction#GO:0070161;cell junction#GO:0030054;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516 GORGO|Ensembl=ENSGGOG00000015465.3|UniProtKB=G3RHG8 G3RHG8 RHCG PTHR11730:SF30 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE C channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;apical part of cell#GO:0045177 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000027028.2|UniProtKB=G3SGV1 G3SGV1 S100P PTHR11639:SF139 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-P cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870;endothelial cell migration#GO:0043542 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000025072.2|UniProtKB=G3S422 G3S422 WDFY2 PTHR46189:SF3 LD41958P WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 2 regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;positive regulation of fat cell differentiation#GO:0045600;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000009165.3|UniProtKB=G3R1A1 G3R1A1 EIF2B1 PTHR45860:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT ALPHA translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000011446.3|UniProtKB=G3R735 G3R735 SCP2 PTHR24314:SF20 NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED STEROL CARRIER PROTEIN 2 peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000005913.3|UniProtKB=G3QSZ1 G3QSZ1 PTHR10183:SF280 CALPAIN CALPAIN-12 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000023062.2|UniProtKB=G3RPN2 G3RPN2 C16H15orf40 PTHR13420:SF7 UPF0235 PROTEIN C15ORF40 UPF0235 PROTEIN C15ORF40 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000005267.3|UniProtKB=G3S7C5 G3S7C5 PSRC1 PTHR21584:SF1 DIFFERENTIAL DISPLAY AND ACTIVATED BY P53 DDA3 /G2 S PHASE EXPRESSED 1 PROLINE_SERINE-RICH COILED-COIL PROTEIN 1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 organelle fission#GO:0048285;localization#GO:0051179;nuclear division#GO:0000280;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic metaphase chromosome alignment#GO:0007080;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;chromosome localization#GO:0050000;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987 spindle pole#GO:0000922;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;spindle#GO:0005819;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 GORGO|Ensembl=ENSGGOG00000005510.3|UniProtKB=G3QRX8 G3QRX8 RNF44 PTHR46171:SF2 GH10160P RING FINGER PROTEIN 44 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 GORGO|Ensembl=ENSGGOG00000040187.1|UniProtKB=A0A2I2YD06 A0A2I2YD06 CALML4 PTHR23048:SF45 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN-LIKE PROTEIN 4 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000010966.3|UniProtKB=G3RM46 G3RM46 PTHR44427:SF12 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 3 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000004877.3|UniProtKB=G3QQB4 G3QQB4 FKBPL PTHR11242:SF9 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED FK506-BINDING PROTEIN-LIKE metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000010716.3|UniProtKB=G3R590 G3R590 TRAPPC10 PTHR13251:SF3 EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000025745.2|UniProtKB=G3S5W2 G3S5W2 LOC101129736 PTHR26452:SF807 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000219.3|UniProtKB=G3QDA6 G3QDA6 RNF167 PTHR22765:SF35 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF167 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;lysosome localization#GO:0032418;biological regulation#GO:0065007;organelle localization#GO:0051640;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;localization#GO:0051179;protein metabolic process#GO:0019538;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011976.3|UniProtKB=G3R8H2 G3R8H2 PTHR23214:SF1 NEUROFILAMENT TRIPLET H PROTEIN NEUROFILAMENT HEAVY POLYPEPTIDE structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 intermediate filament bundle assembly#GO:0045110;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;axon development#GO:0061564;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;axon#GO:0030424;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;neuron projection#GO:0043005;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000037688.1|UniProtKB=A0A2I2ZUT8 A0A2I2ZUT8 PTHR23359:SF225 NUCLEOTIDE KINASE SUBFAMILY NOT NAMED phosphotransferase activity, phosphate group as acceptor#GO:0016776;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740 purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleoside diphosphate metabolic process#GO:0009132;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleoside phosphate biosynthetic process#GO:1901293;ADP metabolic process#GO:0046031;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000005079.3|UniProtKB=G3QQV0 G3QQV0 HTN1 PTHR15057:SF2 STATHERIN HISTATIN-1 response to external stimulus#GO:0009605;defense response#GO:0006952;humoral immune response#GO:0006959;cell killing#GO:0001906;antimicrobial humoral response#GO:0019730;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;cellular process#GO:0009987;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;immune system process#GO:0002376;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002586.3|UniProtKB=G3QJF1 G3QJF1 MTURN PTHR32008:SF2 MATURIN MATURIN regulation of hemopoiesis#GO:1903706;regulation of myeloid cell differentiation#GO:0045637;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002255.3|UniProtKB=G3QIK8 G3QIK8 SLC16A14 PTHR11360:SF239 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 14 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001520.3|UniProtKB=G3QGP2 G3QGP2 METAP1 PTHR43330:SF7 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000005718.3|UniProtKB=P0DJG2 P0DJG2 APOA2 PTHR11027:SF0 APOLIPOPROTEIN A-II APOLIPOPROTEIN A-II protein-containing complex binding#GO:0044877;lipoprotein particle binding#GO:0071813;binding#GO:0005488;protein-lipid complex binding#GO:0071814 lipid localization#GO:0010876;chemical homeostasis#GO:0048878;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;sterol transport#GO:0015918;organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;lipid homeostasis#GO:0055088;lipid transport#GO:0006869;homeostatic process#GO:0042592 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;high-density lipoprotein particle#GO:0034364;plasma lipoprotein particle#GO:0034358;lipoprotein particle#GO:1990777;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;extracellular region#GO:0005576 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000043496.1|UniProtKB=A0A2I2YFD9 A0A2I2YFD9 PTHR23138:SF190 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2 ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nucleocytoplasmic transport#GO:0006913;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein transport#GO:0015031;protein import into nucleus#GO:0006606;protein localization to organelle#GO:0033365 membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle envelope#GO:0031967 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014625.3|UniProtKB=G3S037 G3S037 WDR73 PTHR46947:SF1 WD REPEAT-CONTAINING PROTEIN 73 INTEGRATOR COMPLEX ASSEMBLY FACTOR WDR73 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819 GORGO|Ensembl=ENSGGOG00000007258.3|UniProtKB=G3QWE5 G3QWE5 ZWINT PTHR31504:SF1 ZW10 INTERACTOR ZWINT OUTER KINETOCHORE KNL1 COMPLEX SUBUNIT ZWINT negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of chromosome organization#GO:2001251;organelle fission#GO:0048285;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;regulation of mitotic sister chromatid separation#GO:0010965;establishment of localization#GO:0051234;regulation of mitotic nuclear division#GO:0007088;cellular component organization#GO:0016043;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;mitotic spindle assembly checkpoint signaling#GO:0007094;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;negative regulation of cell cycle#GO:0045786;negative regulation of organelle organization#GO:0010639;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;negative regulation of cell cycle phase transition#GO:1901988;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;negative regulation of biological process#GO:0048519;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;nuclear division#GO:0000280;cellular localization#GO:0051641;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;cellular component organization or biogenesis#GO:0071840 kinetochore#GO:0000776;chromosome#GO:0005694;organelle lumen#GO:0043233;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;dendrite#GO:0030425;intracellular organelle lumen#GO:0070013;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;neuron projection#GO:0043005;condensed chromosome, centromeric region#GO:0000779;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;supramolecular complex#GO:0099080;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000006861.3|UniProtKB=G3QVE5 G3QVE5 PSMD9 PTHR12651:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829 protein modifying enzyme#PC00260;protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000013065.3|UniProtKB=G3RBA4 G3RBA4 IL34 PTHR28606:SF1 INTERLEUKIN-34 INTERLEUKIN-34 binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of developmental process#GO:0050793;regulation of myeloid cell differentiation#GO:0045637;regulation of hemopoiesis#GO:1903706;regulation of cell population proliferation#GO:0042127;positive regulation of immune system process#GO:0002684;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;biological regulation#GO:0065007;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128 GORGO|Ensembl=ENSGGOG00000009149.3|UniProtKB=G3R187 G3R187 SECTM1 PTHR15123:SF5 SECRETED AND TRANSMEMBRANE PROTEIN 1 SECRETED AND TRANSMEMBRANE PROTEIN 1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of biosynthetic process#GO:0009891;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;regulation of immune response#GO:0050776;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of adaptive immune response#GO:0002821;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of lymphocyte mediated immunity#GO:0002706;regulation of cytokine production involved in immune response#GO:0002718 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000026016.2|UniProtKB=G3SJU5 G3SJU5 SNW1 PTHR12096:SF0 NUCLEAR PROTEIN SKIP-RELATED SNW DOMAIN-CONTAINING PROTEIN 1 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000011521.3|UniProtKB=G3R7A6 G3R7A6 CCDC50 PTHR22115:SF1 C3ORF6 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 50 binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007757.3|UniProtKB=A0A2I2ZY83 A0A2I2ZY83 ITGB3 PTHR10082:SF25 INTEGRIN BETA SUBUNIT INTEGRIN BETA-3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 signaling#GO:0023052;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;hemostasis#GO:0007599;integrin-mediated signaling pathway#GO:0007229;regulation of biological quality#GO:0065008;wound healing#GO:0042060;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell activation#GO:0001775;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;homotypic cell-cell adhesion#GO:0034109;biological regulation#GO:0065007;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;coagulation#GO:0050817;response to stress#GO:0006950;response to wounding#GO:0009611;cell-cell adhesion#GO:0098609;blood coagulation#GO:0007596;platelet activation#GO:0030168;cell surface receptor signaling pathway#GO:0007166;platelet aggregation#GO:0070527;cell adhesion mediated by integrin#GO:0033627 focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;integrin complex#GO:0008305;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;signaling receptor complex#GO:0043235 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931;Blood coagulation#P00011>GP IIIa#P00458 GORGO|Ensembl=ENSGGOG00000039004.1|UniProtKB=A0A2I2Z1F2 A0A2I2Z1F2 U2AF1 PTHR12620:SF11 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT SPLICING FACTOR U2AF 35 KDA SUBUNIT RNA binding#GO:0003723;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002;binding#GO:0005488 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000001902.3|UniProtKB=G3QHN7 G3QHN7 MRPL9 PTHR21368:SF27 50S RIBOSOMAL PROTEIN L9 LARGE RIBOSOMAL SUBUNIT PROTEIN BL9M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000005196.3|UniProtKB=G3S124 G3S124 PTHR11738:SF177 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL3 molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008259.3|UniProtKB=G3SCL2 G3SCL2 JAM2 PTHR44663:SF2 JUNCTIONAL ADHESION MOLECULE B JUNCTIONAL ADHESION MOLECULE B cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000014747.3|UniProtKB=G3RFM7 G3RFM7 TIAM1 PTHR46001:SF1 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR TIAM1 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of axonogenesis#GO:0050770;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;regulation of developmental process#GO:0050793;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 Ras Pathway#P04393>Tiam1#P04571 GORGO|Ensembl=ENSGGOG00000038467.1|UniProtKB=A0A2I2ZNY9 A0A2I2ZNY9 PTHR45633:SF14 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 cellular component organization or biogenesis#GO:0071840;protein maturation#GO:0051604;gene expression#GO:0010467;lymphocyte activation#GO:0046649;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;organelle organization#GO:0006996;cellular localization#GO:0051641;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839;apoptotic process#GO:0006915;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;transport#GO:0006810;intracellular transport#GO:0046907;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biosynthetic process#GO:0009058;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of lymphocyte activation#GO:0051251;cellular response to topologically incorrect protein#GO:0035967;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;positive regulation of type I interferon production#GO:0032481;programmed cell death#GO:0012501;positive regulation of leukocyte activation#GO:0002696;metabolic process#GO:0008152;regulation of multicellular organismal process#GO:0051239;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;response to stress#GO:0006950;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of metabolic process#GO:0009893;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;regulation of lymphocyte activation#GO:0051249;regulation of cell activation#GO:0050865;T cell activation#GO:0042110;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;establishment of localization#GO:0051234;regulation of leukocyte cell-cell adhesion#GO:1903037;mitochondrial protein import pathway#GO:7770058;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;cell activation#GO:0001775;cellular response to unfolded protein#GO:0034620;positive regulation of cytokine production#GO:0001819;positive regulation of cell adhesion#GO:0045785;cell death#GO:0008219;leukocyte activation#GO:0045321 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000013078.3|UniProtKB=A0A2I2YGX3 A0A2I2YGX3 SAE1 PTHR10953:SF201 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 1 sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874 post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein sumoylation#GO:0016925;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 GORGO|Ensembl=ENSGGOG00000003786.3|UniProtKB=G3QMH9 G3QMH9 PNPO PTHR10851:SF0 PYRIDOXINE-5-PHOSPHATE OXIDASE PYRIDOXINE-5'-PHOSPHATE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidase#PC00175;oxidoreductase#PC00176 Vitamin B6 metabolism#P02787>Pyridoxamine phosphate oxidase#P03236;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine-5-phosphate oxidase#P03120;Pyridoxal phosphate salvage pathway#P02770>Pyridoxine-5-phosphate oxidase#P03123;Pyridoxal-5-phosphate biosynthesis#P02759>Pyridoxine-5-phosphate oxidase#P03061 GORGO|Ensembl=ENSGGOG00000006341.3|UniProtKB=A0A2I2Z7F9 A0A2I2Z7F9 MED6 PTHR13104:SF0 MED-6-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000001417.3|UniProtKB=G3QGE4 G3QGE4 SEL1L3 PTHR44444:SF1 PROTEIN SEL-1 HOMOLOG 3 PROTEIN SEL-1 HOMOLOG 3 GORGO|Ensembl=ENSGGOG00000001098.3|UniProtKB=G3QFK6 G3QFK6 SCD PTHR11351:SF102 ACYL-COA DESATURASE STEAROYL-COA DESATURASE oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914 lipid biosynthetic process#GO:0008610;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000016867.3|UniProtKB=G3RL25 G3RL25 SGK3 PTHR24351:SF197 RIBOSOMAL PROTEIN S6 KINASE SERINE_THREONINE-PROTEIN KINASE SGK1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001159.3|UniProtKB=G3QFR4 G3QFR4 SYTL4 PTHR45716:SF4 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 4 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810 plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000007693.3|UniProtKB=A0A2I2ZJB2 A0A2I2ZJB2 TBXT PTHR11267:SF83 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR T RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 tissue development#GO:0009888;multicellular organismal process#GO:0032501;regionalization#GO:0003002;epithelium development#GO:0060429;mesoderm formation#GO:0001707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;mesoderm morphogenesis#GO:0048332;heart morphogenesis#GO:0003007;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;heart development#GO:0007507;embryo development#GO:0009790;cellular process#GO:0009987;animal organ development#GO:0048513;mesoderm development#GO:0007498;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;anterior/posterior pattern specification#GO:0009952;cell fate specification#GO:0001708;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;cell differentiation#GO:0030154;gastrulation#GO:0007369;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;formation of primary germ layer#GO:0001704 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 GORGO|Ensembl=ENSGGOG00000011866.3|UniProtKB=G3R884 G3R884 PHAF1 PTHR13465:SF5 UPF0183 PROTEIN PHAGOSOME ASSEMBLY FACTOR 1 vesicle-mediated transport#GO:0016192;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;transport#GO:0006810;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951 presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle subcompartment#GO:0031984;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;somatodendritic compartment#GO:0036477;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;dendritic tree#GO:0097447;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000006745.3|UniProtKB=G3SJV5 G3SJV5 PPP1R1B PTHR15417:SF2 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1B molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cellular response to nitrogen compound#GO:1901699;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell body#GO:0044297 protein-binding activity modulator#PC00095;phosphatase inhibitor#PC00183;phosphatase modulator#PC00184 Nicotine pharmacodynamics pathway#P06587>PPP1R1B#P06589;Dopamine receptor mediated signaling pathway#P05912>DARPP-32#P05950 GORGO|Ensembl=ENSGGOG00000005655.3|UniProtKB=A0A2I2YAA3 A0A2I2YAA3 CD209 PTHR22802:SF197 C-TYPE LECTIN SUPERFAMILY MEMBER CD209 ANTIGEN small molecule binding#GO:0036094;binding#GO:0005488;monosaccharide binding#GO:0048029;signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000042302.1|UniProtKB=A0A2I2ZD71 A0A2I2ZD71 TPD52L3 PTHR19307:SF5 TUMOR PROTEIN D52 TUMOR PROTEIN D55 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007561.3|UniProtKB=A0A2I2Y4H7 A0A2I2Y4H7 ARHGEF7 PTHR46026:SF3 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 7 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 cell leading edge#GO:0031252;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000015866.3|UniProtKB=G3RIH8 G3RIH8 SLTM PTHR15683:SF5 SCAFFOLD ATTACHMENT FACTOR B-RELATED SAFB-LIKE TRANSCRIPTION MODULATOR cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000034866.2|UniProtKB=G3SKL3 G3SKL3 SLC9A9 PTHR10110:SF61 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 9 metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 recycling endosome#GO:0055037;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000006851.3|UniProtKB=G3QVE7 G3QVE7 ANKIB1 PTHR11685:SF463 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING ANKYRIN REPEAT AND IBR DOMAIN-CONTAINING PROTEIN 1 acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000003363.3|UniProtKB=A0A2I2YC32 A0A2I2YC32 KIAA0825 PTHR33960:SF1 SIMILAR TO KIAA0825 PROTEIN KIAA0825 HOMOLOG GORGO|Ensembl=ENSGGOG00000025261.2|UniProtKB=G3S1F4 G3S1F4 SLC25A15 PTHR45624:SF22 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ORNITHINE TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;cellular localization#GO:0051641;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;intracellular transport#GO:0046907;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000041355.1|UniProtKB=A0A2I2Y3G9 A0A2I2Y3G9 KCNE3 PTHR15282:SF6 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 3 transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;channel activity#GO:0015267;channel regulator activity#GO:0016247;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;potassium channel regulator activity#GO:0015459;voltage-gated potassium channel activity#GO:0005249;binding#GO:0005488;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832 cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;cardiac muscle cell action potential involved in contraction#GO:0086002;regulation of membrane potential#GO:0042391;heart process#GO:0003015;action potential#GO:0001508;muscle system process#GO:0003012;regulation of biological process#GO:0050789;export from cell#GO:0140352;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;actin filament-based movement#GO:0030048;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;potassium ion transport#GO:0006813;transport#GO:0006810;muscle contraction#GO:0006936;regulation of system process#GO:0044057;system process#GO:0003008;heart contraction#GO:0060047;establishment of localization#GO:0051234;cardiac muscle cell contraction#GO:0086003;regulation of heart contraction#GO:0008016;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;actin-mediated cell contraction#GO:0070252;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;localization#GO:0051179;monoatomic cation transport#GO:0006812 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000010649.3|UniProtKB=G3R524 G3R524 PTHR45702:SF4 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 10 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;proteolysis#GO:0006508;cell communication#GO:0007154;protein metabolic process#GO:0019538;membrane protein proteolysis#GO:0033619;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;membrane protein ectodomain proteolysis#GO:0006509;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219 cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 protein modifying enzyme#PC00260;protease#PC00190 Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 GORGO|Ensembl=ENSGGOG00000005348.3|UniProtKB=G3QRJ0 G3QRJ0 ACAP3 PTHR23180:SF407 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;nervous system development#GO:0007399;cell migration#GO:0016477;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;neurogenesis#GO:0022008;neuron migration#GO:0001764;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 GORGO|Ensembl=ENSGGOG00000006699.3|UniProtKB=G3QUZ7 G3QUZ7 PTHR43836:SF3 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;O-methyltransferase activity#GO:0008171;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 amine metabolic process#GO:0009308;phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576;metabolic process#GO:0008152;amine catabolic process#GO:0009310;catecholamine metabolic process#GO:0006584 axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;membrane#GO:0016020 methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>COMT#P00069;Dopamine receptor mediated signaling pathway#P05912>COMT#P05944 GORGO|Ensembl=ENSGGOG00000017085.3|UniProtKB=G3RLL7 G3RLL7 PTHR21389:SF0 P53 INDUCED PROTEIN ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236;metabolic process#GO:0008152;autophagy#GO:0006914;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000003881.3|UniProtKB=G3QMR3 G3QMR3 ACD PTHR14487:SF3 ADRENOCORTICAL DYSPLASIA PROTEIN ACD ADRENOCORTICAL DYSPLASIA PROTEIN HOMOLOG GORGO|Ensembl=ENSGGOG00000006531.3|UniProtKB=A0A2I2Z3G1 A0A2I2Z3G1 LOC101146566 PTHR23424:SF36 SERUM AMYLOID A SERUM AMYLOID A-1 PROTEIN apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000004668.3|UniProtKB=G3QPS4 G3QPS4 MNS1 PTHR19265:SF0 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;cilium#GO:0005929 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000026575.2|UniProtKB=A0A2I2ZRI9 A0A2I2ZRI9 LOC109024079 PTHR12884:SF36 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000002465.3|UniProtKB=A0A2I2ZCG0 A0A2I2ZCG0 CCDC175 PTHR35347:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 175 COILED-COIL DOMAIN-CONTAINING PROTEIN 175 GORGO|Ensembl=ENSGGOG00000024982.2|UniProtKB=A0A2I2ZRF4 A0A2I2ZRF4 PTHR23048:SF41 MYOSIN LIGHT CHAIN 1, 3 EF-HAND DOMAIN-CONTAINING PROTEIN ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;structural molecule activity#GO:0005198;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000003793.3|UniProtKB=G3QMJ6 G3QMJ6 DOP1B PTHR14042:SF23 DOPEY-RELATED PROTEIN DOP1B localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;retrograde transport, vesicle recycling within Golgi#GO:0000301;establishment of localization in cell#GO:0051649;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987 intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;early endosome membrane#GO:0031901;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000003478.3|UniProtKB=G3QLR0 G3QLR0 RRN3 PTHR12790:SF0 TRANSCRIPTION INITIATION FACTOR IA RRN3 RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription initiation at RNA polymerase I promoter#GO:0006361;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 GORGO|Ensembl=ENSGGOG00000007643.3|UniProtKB=G3QXD5 G3QXD5 DYNC2I2 PTHR12442:SF26 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043 cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;dynein complex#GO:0030286;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;catalytic complex#GO:1902494;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000002373.3|UniProtKB=G3QIW8 G3QIW8 CENPF PTHR18874:SF10 CMF/LEK/CENP CELL DIVISION-RELATED CENTROMERE PROTEIN F GORGO|Ensembl=ENSGGOG00000009071.3|UniProtKB=G3RSI9 G3RSI9 NFKB1 PTHR24169:SF9 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to peptide#GO:1901652;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;intracellular signaling cassette#GO:0141124;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;defense response to symbiont#GO:0140546;non-canonical NF-kappaB signal transduction#GO:0038061;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;response to other organism#GO:0051707;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Apoptosis signaling pathway#P00006>NFkappaB#P00297;B cell activation#P00010>NFkappaB#P00370;Toll receptor signaling pathway#P00054>NFkappaB#P01354;T cell activation#P00053>NFkappaB#P01298 GORGO|Ensembl=ENSGGOG00000037940.1|UniProtKB=A0A2I2ZGJ3 A0A2I2ZGJ3 PTHR48112:SF43 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B3 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000015061.3|UniProtKB=G3RGF5 G3RGF5 CMAS PTHR21485:SF3 HAD SUPERFAMILY MEMBERS CMAS AND KDSC N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleotidyltransferase#PC00174;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001514.4|UniProtKB=A0A2I2ZSX7 A0A2I2ZSX7 SPATA7 PTHR14917:SF2 SPERMATOGENESIS-ASSOCIATED PROTEIN 7 SPERMATOGENESIS-ASSOCIATED PROTEIN 7 multicellular organismal-level homeostasis#GO:0048871;microtubule-based process#GO:0007017;tissue homeostasis#GO:0001894;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;retina homeostasis#GO:0001895;cytoskeleton organization#GO:0007010;homeostatic process#GO:0042592;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;9+0 non-motile cilium#GO:0097731;microtubule cytoskeleton#GO:0015630;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;axoneme#GO:0005930;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000005729.3|UniProtKB=G3QSH2 G3QSH2 LAMP3 PTHR11506:SF30 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 3 localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000012515.3|UniProtKB=G3R9W1 G3R9W1 LIX1 PTHR31139:SF5 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG PROTEIN LIMB EXPRESSION 1 HOMOLOG organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001764.3|UniProtKB=G3QHB2 G3QHB2 GJA3 PTHR11984:SF12 CONNEXIN GAP JUNCTION ALPHA-3 PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 cell communication#GO:0007154;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of biological process#GO:0050789 cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070;gap junction#PC00105 GORGO|Ensembl=ENSGGOG00000000337.3|UniProtKB=G3QDK9 G3QDK9 ZNF667 PTHR23226:SF378 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 667 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016000.3|UniProtKB=A0A2I2YJ76 A0A2I2YJ76 LOC101138428 PTHR35250:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 4 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 5 GORGO|Ensembl=ENSGGOG00000040936.1|UniProtKB=A0A2I2Y7L0 A0A2I2Y7L0 PTHR31905:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 PROTEIN MIX23 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007679.3|UniProtKB=G3QXH0 G3QXH0 DTNB PTHR12268:SF22 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN BETA multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399;cellular process#GO:0009987;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;developmental process#GO:0032502;neuron differentiation#GO:0030182 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000026927.2|UniProtKB=G3RUP5 G3RUP5 PTN PTHR13850:SF1 PLEIOTROPHIN FAMILY MEMBER PLEIOTROPHIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000014085.3|UniProtKB=G3RDY3 G3RDY3 F10 PTHR24278:SF28 COAGULATION FACTOR COAGULATION FACTOR X serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 Blood coagulation#P00011>FXa#P00445;Blood coagulation#P00011>FX#P00430 GORGO|Ensembl=ENSGGOG00000036830.1|UniProtKB=A0A2I2Z704 A0A2I2Z704 PTHR31911:SF3 PROTEIN FAM133 PROTEIN FAM133B RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000042968.1|UniProtKB=A0A2I2YZ36 A0A2I2YZ36 CILP PTHR15031:SF3 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 1 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000013150.3|UniProtKB=G3RBH2 G3RBH2 PDHB PTHR11624:SF116 DEHYDROGENASE RELATED PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;acetyl-CoA metabolic process#GO:0006084;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 acetyltransferase complex#GO:1902493;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;oxidoreductase complex#GO:1990204 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000007784.3|UniProtKB=G3QXQ7 G3QXQ7 EAPP PTHR15967:SF1 E2F-ASSOCIATED PHOSPHOPROTEIN E2F-ASSOCIATED PHOSPHOPROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002361.3|UniProtKB=G3QIV1 G3QIV1 PTHR28638:SF2 CELL CYCLE PROGRESSION PROTEIN 1 CELL CYCLE PROGRESSION PROTEIN 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000038562.1|UniProtKB=G3RK80 G3RK80 SERPINB9 PTHR11461:SF350 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B9 peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000022359.2|UniProtKB=G3RZK6 G3RZK6 DST PTHR23169:SF24 ENVOPLAKIN DYSTONIN tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;response to wounding#GO:0009611;response to stress#GO:0006950;cytoskeleton organization#GO:0007010;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103;wound healing#GO:0042060;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161 intermediate filament#PC00129;intermediate filament binding protein#PC00130 GORGO|Ensembl=ENSGGOG00000009717.3|UniProtKB=G3SBS7 G3SBS7 TLE3 PTHR10814:SF24 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 3 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 GORGO|Ensembl=ENSGGOG00000022019.2|UniProtKB=G3S202 G3S202 LOC101135821 PTHR22879:SF14 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 2A-RELATED GORGO|Ensembl=ENSGGOG00000043682.1|UniProtKB=A0A2I2YVE2 A0A2I2YVE2 ZNF197 PTHR23226:SF290 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 197 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000041964.1|UniProtKB=A0A2I2Y505 A0A2I2Y505 CFAP99 PTHR34649:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000002417.3|UniProtKB=G3SCD2 G3SCD2 PDLIM2 PTHR24214:SF1 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular process#GO:0009987;organelle organization#GO:0006996;system development#GO:0048731;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;circulatory system development#GO:0072359;cellular component organization#GO:0016043 adherens junction#GO:0005912;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;sarcomere#GO:0030017;actin filament#GO:0005884;I band#GO:0031674;cytoskeleton#GO:0005856;stress fiber#GO:0001725;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;Z disc#GO:0030018;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;cell-cell junction#GO:0005911;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000000800.3|UniProtKB=A0A2I2YEQ6 A0A2I2YEQ6 ARHGAP27 PTHR23176:SF104 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 27 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000011731.3|UniProtKB=G3R7U6 G3R7U6 AKR1B1 PTHR11732:SF294 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000002116.3|UniProtKB=G3QI78 G3QI78 PTHR13141:SF4 TRANSMEMBRANE PROTEIN 242 TRANSMEMBRANE PROTEIN 242 GORGO|Ensembl=ENSGGOG00000016759.3|UniProtKB=A0A2I2Z8P0 A0A2I2Z8P0 HIGD1A PTHR12297:SF5 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A, MITOCHONDRIAL regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037768.1|UniProtKB=A0A2I2Z5X2 A0A2I2Z5X2 HES6 PTHR10985:SF11 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION COFACTOR HES-6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of neurogenesis#GO:0050767;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000026351.2|UniProtKB=A0A2I2Z1E4 A0A2I2Z1E4 NASP PTHR15081:SF1 NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED NUCLEAR AUTOANTIGENIC SPERM PROTEIN protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 cellular component assembly#GO:0022607;chromatin organization#GO:0006325;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;kinetochore organization#GO:0051383;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000007093.3|UniProtKB=G3QVZ5 G3QVZ5 HYAL1 PTHR11769:SF23 HYALURONIDASE HYALURONIDASE-1 macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;glycosaminoglycan catabolic process#GO:0006027;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000008286.3|UniProtKB=G3QZ01 G3QZ01 GINM1 PTHR28549:SF1 GLYCOPROTEIN INTEGRAL MEMBRANE PROTEIN 1 GLYCOPROTEIN INTEGRAL MEMBRANE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000041871.1|UniProtKB=A0A2I2YFX7 A0A2I2YFX7 PTHR14894:SF1 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 CDK5 REGULATORY SUBUNIT ASSOCIATED PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;biological regulation#GO:0065007 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000187.3|UniProtKB=G3QD75 G3QD75 CC2D1B PTHR13076:SF5 COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000010790.3|UniProtKB=A0A2I2ZBL2 A0A2I2ZBL2 DGKI PTHR11255:SF92 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE IOTA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;biological regulation#GO:0065007;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000038620.1|UniProtKB=A0A2I2Z1I2 A0A2I2Z1I2 PTHR23142:SF6 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38B gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000010719.3|UniProtKB=G3R584 G3R584 PRMT2 PTHR11006:SF92 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 2 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;histone modifying activity#GO:0140993;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007856.3|UniProtKB=G3QXX9 G3QXX9 TENM2 PTHR11219:SF8 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell adhesion#GO:0007155;axonogenesis#GO:0007409;neuron development#GO:0048666;synaptic membrane adhesion#GO:0099560;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;cell junction organization#GO:0034330;synapse organization#GO:0050808;anatomical structure development#GO:0048856;system development#GO:0048731;axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000016621.3|UniProtKB=G3RKF0 G3RKF0 TUBB1 PTHR11588:SF112 TUBULIN TUBULIN BETA-1 CHAIN nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 tubulin#PC00228;cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 GORGO|Ensembl=ENSGGOG00000016550.3|UniProtKB=G3RK86 G3RK86 CIAO2A PTHR12377:SF6 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2A macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000012805.3|UniProtKB=A0A2I2Z2R3 A0A2I2Z2R3 PPP1R7 PTHR45973:SF23 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;chromosome segregation#GO:0007059 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000010183.3|UniProtKB=A0A2I2Y2U9 A0A2I2Y2U9 BEGAIN PTHR28664:SF2 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 BRAIN-ENRICHED GUANYLATE KINASE-ASSOCIATED PROTEIN regulation of biological quality#GO:0065008;cell communication#GO:0007154;nervous system process#GO:0050877;trans-synaptic signaling#GO:0099537;chemical synaptic transmission, postsynaptic#GO:0099565;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of postsynaptic membrane potential#GO:0060078;chemical synaptic transmission#GO:0007268;system process#GO:0003008;regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000008434.3|UniProtKB=G3QZD4 G3QZD4 NGFR PTHR46605:SF3 TUMOR NECROSIS FACTOR RECEPTOR TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16 coreceptor activity#GO:0015026;signaling receptor activity#GO:0038023;binding#GO:0005488;death receptor activity#GO:0005035;transmembrane signaling receptor activity#GO:0004888;growth factor binding#GO:0019838;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000041060.1|UniProtKB=A0A2I2YZU4 A0A2I2YZU4 DRD1 PTHR24247:SF217 5-HYDROXYTRYPTAMINE RECEPTOR D(1A) DOPAMINE RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 GORGO|Ensembl=ENSGGOG00000002695.3|UniProtKB=A0A2I2YMK4 A0A2I2YMK4 NAALADL1 PTHR10404:SF50 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE AMINOPEPTIDASE NAALADL1 peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000006802.3|UniProtKB=G3QV94 G3QV94 UTS2 PTHR14447:SF0 UROTENSIN 2 UROTENSIN-2 circulatory system process#GO:0003013;regulation of blood pressure#GO:0008217;regulation of biological quality#GO:0065008;system process#GO:0003008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000001804.3|UniProtKB=G3SJR2 G3SJR2 FLYWCH1 PTHR31665:SF3 FLYWCH FAMILY MEMBER 2-RELATED FLYWCH-TYPE ZINC FINGER-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000028118.2|UniProtKB=G3RT32 G3RT32 NGRN PTHR13475:SF4 NEUGRIN NEUGRIN cellular process#GO:0009987;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;mitochondrial ribosome assembly#GO:0061668;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000008378.4|UniProtKB=A0A2I2YY21 A0A2I2YY21 CHRNA4 PTHR18945:SF401 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4 acetylcholine receptor activity#GO:0015464;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261 regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;neuromuscular synaptic transmission#GO:0007274;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;establishment of localization#GO:0051234;transport#GO:0006810;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537 synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;synapse#GO:0045202 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA4#P06594;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 GORGO|Ensembl=ENSGGOG00000007442.3|UniProtKB=G3QWW2 G3QWW2 NME8 PTHR46135:SF2 NME/NM23 FAMILY MEMBER 8 PROTEIN NME8 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987 sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;sperm principal piece#GO:0097228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000015975.3|UniProtKB=G3RIS8 G3RIS8 ATP7B PTHR43520:SF30 ATP7, ISOFORM B COPPER-TRANSPORTING ATPASE 2 cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;metal ion binding#GO:0046872;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;binding#GO:0005488;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;copper ion binding#GO:0005507;transporter activity#GO:0005215 inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;copper ion transmembrane transport#GO:0035434;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000015723.3|UniProtKB=G3RI49 G3RI49 PNOC PTHR11438:SF2 PROENKEPHALIN PREPRONOCICEPTIN protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664 regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;neuropeptide signaling pathway#GO:0007218;sensory perception of pain#GO:0019233;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell body#GO:0044297;cell periphery#GO:0071944 intercellular signal molecule#PC00207;neuropeptide#PC00162;peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000003494.3|UniProtKB=G3QLR8 G3QLR8 SLC25A10 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER dicarboxylic acid transmembrane transporter activity#GO:0005310;succinate transmembrane transporter activity#GO:0015141;C4-dicarboxylate transmembrane transporter activity#GO:0015556;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 dicarboxylic acid transport#GO:0006835;phosphate ion transport#GO:0006817;carboxylic acid transmembrane transport#GO:1905039;succinate transport#GO:0015744;cellular process#GO:0009987;inorganic anion transport#GO:0015698;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000011834.3|UniProtKB=G3R868 G3R868 PTHR13650:SF2 SPATACSIN SPATACSIN axo-dendritic transport#GO:0008088;axon development#GO:0061564;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;intracellular transport#GO:0046907;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;chemical synaptic transmission#GO:0007268;microtubule-based movement#GO:0007018;anterograde trans-synaptic signaling#GO:0098916;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;system development#GO:0048731;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;neuron projection development#GO:0031175;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle localization#GO:0097479;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;establishment of vesicle localization#GO:0051650;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;axonogenesis#GO:0007409;neuron development#GO:0048666 cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425 GORGO|Ensembl=ENSGGOG00000015916.3|UniProtKB=G3SK08 G3SK08 PTHR19443:SF60 HEXOKINASE HEXOKINASE-2 hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate metabolic process#GO:0005975;homeostatic process#GO:0042592;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;intracellular chemical homeostasis#GO:0055082;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;intracellular glucose homeostasis#GO:0001678;oxoacid metabolic process#GO:0043436;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;cellular homeostasis#GO:0019725;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;pyruvate metabolic process#GO:0006090;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing small molecule metabolic process#GO:0055086;glucose homeostasis#GO:0042593;purine nucleoside diphosphate catabolic process#GO:0009137;ADP catabolic process#GO:0046032 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;cytoplasmic side of membrane#GO:0098562;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;cytosol#GO:0005829;membrane#GO:0016020 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000004497.3|UniProtKB=G3QPC0 G3QPC0 CCDC170 PTHR18863:SF4 TSEC-2-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 170 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000027716.2|UniProtKB=G3SEI6 G3SEI6 ZC2HC1B PTHR13555:SF36 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1B C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000023119.2|UniProtKB=G3S032 G3S032 SHPRH PTHR45865:SF2 E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE SHPRH catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000015614.3|UniProtKB=A0A2I2YJW1 A0A2I2YJW1 C4H17orf50 PTHR37878:SF1 HYPOTHETICAL PROTEIN LOC689039 SIMILAR TO HUMAN CHROMOSOME 17 OPEN READING FRAME 50 GORGO|Ensembl=ENSGGOG00000041363.1|UniProtKB=G3RWL3 G3RWL3 PTHR16776:SF3 EXTRACELLULAR MATRIX PROTEIN 1 EXTRACELLULAR MATRIX PROTEIN 1 biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239;regulation of bone mineralization#GO:0030500;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026 GORGO|Ensembl=ENSGGOG00000024069.2|UniProtKB=A0A2I2ZSY7 A0A2I2ZSY7 YTHDF2 PTHR12357:SF8 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 2 RNA binding#GO:0003723;protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004142.3|UniProtKB=G3QNE9 G3QNE9 KLF12 PTHR23235:SF56 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 12 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013225.3|UniProtKB=G3RBP1 G3RBP1 ELL3 PTHR23288:SF18 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;transcription by RNA polymerase II#GO:0006366;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of biological process#GO:0050789;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;snRNA transcription#GO:0009301;nucleic acid biosynthetic process#GO:0141187;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000010926.3|UniProtKB=G3R5S3 G3R5S3 SHCBP1 PTHR14695:SF8 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED SHC SH2 DOMAIN-BINDING PROTEIN 1 meiotic nuclear division#GO:0140013;spermatogenesis#GO:0007283;developmental process#GO:0032502;response to fibroblast growth factor#GO:0071774;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;male gamete generation#GO:0048232;multicellular organismal reproductive process#GO:0048609;cell communication#GO:0007154;organelle fission#GO:0048285;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;sexual reproduction#GO:0019953;reproductive process#GO:0022414;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cell division#GO:0051301;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;meiotic cell cycle#GO:0051321;male meiotic nuclear division#GO:0007140;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;organelle organization#GO:0006996;cellular response to growth factor stimulus#GO:0071363;cytoskeleton-dependent cytokinesis#GO:0061640;nuclear division#GO:0000280;cytokinesis#GO:0000910;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;gamete generation#GO:0007276;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;response to endogenous stimulus#GO:0009719;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043 GORGO|Ensembl=ENSGGOG00000004984.3|UniProtKB=G3SCN6 G3SCN6 HPS4 PTHR14407:SF9 HERMANSKY-PUDLAK SYNDROME 4 PROTEIN LIGHT-EAR PROTEIN-RELATED BLOC-3 COMPLEX MEMBER HPS4 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular pigmentation#GO:0033059;cellular component assembly#GO:0022607;protein targeting#GO:0006605;pigmentation#GO:0043473;melanosome organization#GO:0032438;organelle assembly#GO:0070925;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234 lysosome#GO:0005764;vesicle#GO:0031982;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 GORGO|Ensembl=ENSGGOG00000011596.3|UniProtKB=G3R7H4 G3R7H4 ATP5F1B PTHR15184:SF88 ATP SYNTHASE ATP SYNTHASE F(1) COMPLEX SUBUNIT BETA, MITOCHONDRIAL proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117 membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ATP synthase#PC00002 ATP synthesis#P02721>F1 beta#P02794 GORGO|Ensembl=ENSGGOG00000008390.3|UniProtKB=G3S8V2 G3S8V2 GPBP1 PTHR14339:SF11 VASCULIN VASCULIN DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000015377.3|UniProtKB=G3RH93 G3RH93 PTHR33722:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT DELTA male gamete generation#GO:0048232;developmental maturation#GO:0021700;sperm capacitation#GO:0048240;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;cellular developmental process#GO:0048869;cell maturation#GO:0048469;microtubule-based process#GO:0007017;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;microtubule-based movement#GO:0007018;gamete generation#GO:0007276;cell motility#GO:0048870;cell differentiation#GO:0030154;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;sperm motility#GO:0097722;anatomical structure maturation#GO:0071695;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285;multicellular organismal reproductive process#GO:0048609;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;sexual reproduction#GO:0019953;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539 cilium#GO:0005929;9+2 motile cilium#GO:0097729;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;sperm principal piece#GO:0097228;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cation channel complex#GO:0034703;transporter complex#GO:1990351;membrane#GO:0016020;cell periphery#GO:0071944;sperm flagellum#GO:0036126;CatSper complex#GO:0036128;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008497.3|UniProtKB=G3QZK1 G3QZK1 AFF1 PTHR10528:SF6 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;system process#GO:0003008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;DNA-templated transcription elongation#GO:0006354;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;gene expression#GO:0010467;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nucleic acid biosynthetic process#GO:0141187;nervous system process#GO:0050877;RNA metabolic process#GO:0016070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000027103.2|UniProtKB=A0A2I2YYV9 A0A2I2YYV9 MREG PTHR34340:SF3 MELANOREGULIN MELANOREGULIN establishment of vesicle localization#GO:0051650;cellular pigmentation#GO:0033059;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;developmental pigmentation#GO:0048066;cellular process#GO:0009987;melanocyte differentiation#GO:0030318;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;pigmentation#GO:0043473 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;melanosome#GO:0042470;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000010712.3|UniProtKB=G3R576 G3R576 CIMIP2C PTHR34924:SF1 UPF0573 PROTEIN C2ORF70 CILIARY MICROTUBULE INNER PROTEIN 2C GORGO|Ensembl=ENSGGOG00000023115.2|UniProtKB=G3SCZ8 G3SCZ8 PDXP PTHR19288:SF94 4-NITROPHENYLPHOSPHATASE-RELATED CHRONOPHIN phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000027366.2|UniProtKB=A0A2I2YH32 A0A2I2YH32 CACNA2D1 PTHR10166:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-1 voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857 transporter complex#GO:1990351;sarcolemma#GO:0042383;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;calcium channel complex#GO:0034704;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796 voltage-gated ion channel#PC00241;transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>Ca2+ channel#P01081 GORGO|Ensembl=ENSGGOG00000013438.3|UniProtKB=G3RC78 G3RC78 ZBTB7B PTHR46105:SF4 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013770.3|UniProtKB=G3RD36 G3RD36 GABARAP PTHR10969:SF20 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN enzyme binding#GO:0019899;signaling receptor binding#GO:0005102;binding#GO:0005488;lipid binding#GO:0008289;protein binding#GO:0005515;ubiquitin-like protein ligase binding#GO:0044389;phospholipid binding#GO:0005543;GABA receptor binding#GO:0050811;ubiquitin protein ligase binding#GO:0031625 response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;cellular component organization#GO:0016043;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;organelle assembly#GO:0070925;cellular response to stress#GO:0033554;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033 vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;organelle membrane#GO:0031090;autophagosome#GO:0005776;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000000642.3|UniProtKB=G3QEE1 G3QEE1 ACE PTHR10514:SF25 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;proteolysis#GO:0006508;positive regulation of blood pressure#GO:0045777;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;macromolecule metabolic process#GO:0043170;system process#GO:0003008;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000013143.3|UniProtKB=G3RMP7 G3RMP7 NEMP1 PTHR13598:SF2 AT07567P-RELATED NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 1 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001275.3|UniProtKB=G3QG10 G3QG10 CST7 PTHR47141:SF1 CYSTATIN-F CYSTATIN-F molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of cell activation#GO:0050865;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;negative regulation of inflammatory response#GO:0050728;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;regulation of developmental process#GO:0050793;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of nervous system development#GO:0051960;positive regulation of cellular process#GO:0048522;regulation of macrophage activation#GO:0043030;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of immune system process#GO:0002683;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of system process#GO:0044057;regulation of response to stimulus#GO:0048583;negative regulation of cell activation#GO:0050866 endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;lytic vacuole#GO:0000323;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;intracellular organelle#GO:0043229;extracellular region#GO:0005576;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000038132.1|UniProtKB=A0A2I2Y9I9 A0A2I2Y9I9 PTHR10562:SF147 SMALL UBIQUITIN-RELATED MODIFIER RAD60_SUMO-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488 protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 organelle lumen#GO:0043233;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000009668.3|UniProtKB=G3R2J1 G3R2J1 NR1D1 PTHR24082:SF113 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 1 sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000010709.3|UniProtKB=A0A2I2ZJ17 A0A2I2ZJ17 UBE2F PTHR24068:SF129 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBE2F catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000006549.3|UniProtKB=G3S1U3 G3S1U3 OPA1 PTHR11566:SF67 DYNAMIN DYNAMIN-LIKE GTPASE OPA1, MITOCHONDRIAL GTPase activity#GO:0003924;microtubule binding#GO:0008017;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 organelle fusion#GO:0048284;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;cytoskeleton#GO:0005856;mitochondrial intermembrane space#GO:0005758 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000016200.3|UniProtKB=G3SCL9 G3SCL9 NTNG2 PTHR10574:SF27 NETRIN/LAMININ-RELATED NETRIN-G2 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 GORGO|Ensembl=ENSGGOG00000014765.3|UniProtKB=A0A2I2YHK7 A0A2I2YHK7 TLE2 PTHR10814:SF4 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of cell communication#GO:0010648;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of canonical Wnt signaling pathway#GO:0060828 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 GORGO|Ensembl=ENSGGOG00000026279.2|UniProtKB=G3S6U6 G3S6U6 LOC101144397 PTHR23226:SF142 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 75C-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008224.3|UniProtKB=G3QYU7 G3QYU7 SUCLA2 PTHR11815:SF14 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;tricarboxylic acid cycle#GO:0006099;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000002470.3|UniProtKB=G3QJ49 G3QJ49 TAF9B PTHR48068:SF5 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 9B structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824 acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;transferase complex#GO:1990234;peptidase complex#GO:1905368;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 GORGO|Ensembl=ENSGGOG00000009774.3|UniProtKB=G3R2T5 G3R2T5 PSMD7 PTHR10540:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502 translation initiation factor#PC00224 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000001228.3|UniProtKB=G3QFX6 G3QFX6 CNKSR3 PTHR12844:SF17 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000038744.1|UniProtKB=A0A2I2ZF62 A0A2I2ZF62 PTHR37154:SF1 MITOREGULIN MITOREGULIN intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000042480.1|UniProtKB=A0A2I2ZIA9 A0A2I2ZIA9 PTHR23115:SF310 TRANSLATION FACTOR TR-TYPE G DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000014823.3|UniProtKB=G3RPM5 G3RPM5 PML PTHR25462:SF302 BONUS, ISOFORM C-RELATED PROTEIN PML catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;SUMO transferase activity#GO:0019789 response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;response to virus#GO:0009615;cell communication#GO:0007154;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;immune system process#GO:0002376;defense response to other organism#GO:0098542;cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to biotic stimulus#GO:0009607 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 p53 pathway#P00059>PML#P04618;p53 pathway#P00059>PML#G04701 GORGO|Ensembl=ENSGGOG00000017190.3|UniProtKB=G3RLW4 G3RLW4 SCMH1 PTHR12247:SF68 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SCMH1 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000011628.3|UniProtKB=G3S4P5 G3S4P5 NTN3 PTHR10574:SF292 NETRIN/LAMININ-RELATED NETRIN-3 neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;dendrite development#GO:0016358;anatomical structure morphogenesis#GO:0009653;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;tissue development#GO:0009888;system development#GO:0048731;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 GORGO|Ensembl=ENSGGOG00000013816.3|UniProtKB=G3RD79 G3RD79 BTC PTHR10740:SF3 TRANSFORMING GROWTH FACTOR ALPHA PROBETACELLULIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840;regulation of mitotic nuclear division#GO:0007088;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;ERBB signaling pathway#GO:0038127;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of nuclear division#GO:0051783;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 GORGO|Ensembl=ENSGGOG00000001052.3|UniProtKB=G3QFG5 G3QFG5 PTHR14098:SF16 SH2 DOMAIN CONTAINING PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 6 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;intracellular signal transduction#GO:0035556;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003291.3|UniProtKB=A0A2I2Y4M8 A0A2I2Y4M8 TMEM104 PTHR16189:SF0 TRANSMEMBRANE PROTEIN 104-RELATED SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 12-RELATED GORGO|Ensembl=ENSGGOG00000022172.2|UniProtKB=G3S7D5 G3S7D5 LDHAL6B PTHR43128:SF8 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A-LIKE 6B oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000012525.3|UniProtKB=G3R9Y3 G3R9Y3 POMT1 PTHR10050:SF51 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 1 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000006983.3|UniProtKB=A0A2I2ZN17 A0A2I2ZN17 NF1 PTHR10194:SF142 RAS GTPASE-ACTIVATING PROTEINS NEUROFIBROMIN GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 GORGO|Ensembl=ENSGGOG00000003616.3|UniProtKB=G3QM28 G3QM28 SNX9 PTHR45827:SF2 SORTING NEXIN SORTING NEXIN-9 ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091 endocytosis#GO:0006897;cell division#GO:0051301;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell cycle#GO:0007049;cellular localization#GO:0051641;cytoskeleton-dependent cytokinesis#GO:0061640;plasma membrane organization#GO:0007009;localization#GO:0051179;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;membrane invagination#GO:0010324;intracellular transport#GO:0046907 vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027266.2|UniProtKB=G3RR33 G3RR33 OR5P3 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003171.3|UniProtKB=G3QKY3 G3QKY3 CD63 PTHR19282:SF471 TETRASPANIN CD63 ANTIGEN regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003904.3|UniProtKB=G3QMT5 G3QMT5 PDXK PTHR10534:SF2 PYRIDOXAL KINASE PYRIDOXAL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;pyridine-containing compound metabolic process#GO:0072524;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine kinase#P03122;Vitamin B6 metabolism#P02787>Pyridoxal kinase#P03244;Pyridoxal phosphate salvage pathway#P02770>Pyridoxal kinase#P03121 GORGO|Ensembl=ENSGGOG00000000558.3|UniProtKB=G3QE64 G3QE64 PPP2R3A PTHR14095:SF3 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT ALPHA enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;embryo development#GO:0009790;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;regionalization#GO:0003002;tissue development#GO:0009888;regulation of canonical Wnt signaling pathway#GO:0060828;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;anterior/posterior pattern specification#GO:0009952;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;regulation of signaling#GO:0023051;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108 protein-containing complex#GO:0032991;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023504.2|UniProtKB=G3S6D8 G3S6D8 EFHC1 PTHR12086:SF9 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;cell motility#GO:0048870;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cytokinesis#GO:0000910;cilium or flagellum-dependent cell motility#GO:0001539;microtubule cytoskeleton organization#GO:0000226;cytoskeleton-dependent cytokinesis#GO:0061640;cilium-dependent cell motility#GO:0060285 intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule#GO:0005874;axoneme#GO:0005930;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;mitotic spindle#GO:0072686;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;spindle#GO:0005819;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000002243.3|UniProtKB=G3QIK3 G3QIK3 SUPT16H PTHR13980:SF15 CDC68 RELATED FACT COMPLEX SUBUNIT SPT16 chromatin binding#GO:0003682;binding#GO:0005488;molecular carrier activity#GO:0140104;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;protein carrier activity#GO:0140597 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000009665.3|UniProtKB=G3R2I6 G3R2I6 CSGALNACT1 PTHR12369:SF19 CHONDROITIN SYNTHASE CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000024347.2|UniProtKB=G3S133 G3S133 EVI5 PTHR22957:SF679 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN ECOTROPIC VIRAL INTEGRATION SITE 5 PROTEIN HOMOLOG molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000013536.3|UniProtKB=G3RCG7 G3RCG7 NDP PTHR28611:SF1 NORRIN NORRIN cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;positive regulation of RNA metabolic process#GO:0051254;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891 GORGO|Ensembl=ENSGGOG00000038213.1|UniProtKB=A0A2I2ZRM0 A0A2I2ZRM0 FIGNL2 PTHR23074:SF33 AAA DOMAIN-CONTAINING FIDGETIN-LIKE PROTEIN 2 ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000041261.1|UniProtKB=A0A2I2YIU2 A0A2I2YIU2 PTHR28630:SF34 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2C GORGO|Ensembl=ENSGGOG00000015419.3|UniProtKB=A0A2I2ZU75 A0A2I2ZU75 TBCB PTHR18916:SF97 DYNACTIN 1-RELATED MICROTUBULE-BINDING TUBULIN-FOLDING COFACTOR B microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010 cell cortex#GO:0005938;microtubule end#GO:1990752;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000011444.3|UniProtKB=G3R734 G3R734 GNL3 PTHR11089:SF11 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000009871.3|UniProtKB=A0A2I2ZX37 A0A2I2ZX37 TRPV1 PTHR10582:SF17 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 1 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;transport#GO:0006810;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;import into cell#GO:0098657;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007184.3|UniProtKB=G3QW82 G3QW82 CUZD1 PTHR14002:SF27 ENDOGLIN/TGF-BETA RECEPTOR TYPE III CUB AND ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007257.3|UniProtKB=G3QWE9 G3QWE9 PPP2R5D PTHR10257:SF89 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT DELTA ISOFORM molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 GORGO|Ensembl=ENSGGOG00000016181.3|UniProtKB=G3RJA4 G3RJA4 MRPS23 PTHR15925:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S23 SMALL RIBOSOMAL SUBUNIT PROTEIN MS23 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016923.3|UniProtKB=G3RUX0 G3RUX0 STAG3 PTHR11199:SF8 STROMAL ANTIGEN COHESIN SUBUNIT SA-3 binding#GO:0005488;chromatin binding#GO:0003682 chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996 organelle#GO:0043226;protein-containing complex#GO:0032991;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000003356.3|UniProtKB=G3QLE9 G3QLE9 CXCL1 PTHR12015:SF192 SMALL INDUCIBLE CYTOKINE A GROWTH-REGULATED ALPHA PROTEIN cytokine#PC00083 CCKR signaling map#P06959>CXCL1#G07268;CCKR signaling map#P06959>CXCL1#G06975 GORGO|Ensembl=ENSGGOG00000016670.3|UniProtKB=G3SIX8 G3SIX8 CACNG8 PTHR12107:SF2 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-8 SUBUNIT voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter regulator activity#GO:0141108;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;channel regulator activity#GO:0016247;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051;nervous system process#GO:0050877;localization within membrane#GO:0051668;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;regulation of synaptic transmission, glutamatergic#GO:0051966;localization#GO:0051179;cell communication#GO:0007154;regulation of biological quality#GO:0065008;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transmission of nerve impulse#GO:0019226;system process#GO:0003008 organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 transporter#PC00227;ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000001895.3|UniProtKB=G3RM52 G3RM52 VAV3 PTHR45818:SF1 PROTEIN VAV GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV3 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of immune response#GO:0050776;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169;B cell activation#P00010>vav#P00368 GORGO|Ensembl=ENSGGOG00000041520.1|UniProtKB=A0A2I2ZGR4 A0A2I2ZGR4 AMFR PTHR15067:SF5 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE AMFR ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;intracellular signal transduction#GO:0035556;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein K48-linked ubiquitination#GO:0070936;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;response to unfolded protein#GO:0006986;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;protein ubiquitination#GO:0016567 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000022080.2|UniProtKB=G3S8K5 G3S8K5 RBM34 PTHR13964:SF24 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4B double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000028059.2|UniProtKB=G3SBC6 G3SBC6 FCRLB PTHR11481:SF94 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;immune response#GO:0006955;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000007526.4|UniProtKB=G3QX47 G3QX47 TNIK PTHR48015:SF39 SERINE/THREONINE-PROTEIN KINASE TAO TRAF2 AND NCK-INTERACTING PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000038545.1|UniProtKB=A0A2I2ZS59 A0A2I2ZS59 PTHR16040:SF6 AUSTRALIN, ISOFORM A-RELATED BOREALIN mitotic cell cycle#GO:0000278;mitotic metaphase chromosome alignment#GO:0007080;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;localization#GO:0051179;organelle fission#GO:0048285;nuclear division#GO:0000280;organelle localization#GO:0051640;chromosome localization#GO:0050000;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310 chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233 GORGO|Ensembl=ENSGGOG00000015362.3|UniProtKB=G3RH69 G3RH69 HSD11B1L PTHR44279:SF3 HYDROXYSTEROID (11-BETA) DEHYDROGENASE 1-LIKE B-RELATED HYDROXYSTEROID 11-BETA-DEHYDROGENASE 1-LIKE PROTEIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000010251.3|UniProtKB=G3RQH5 G3RQH5 CBS PTHR10314:SF194 CYSTATHIONINE BETA-SYNTHASE CYSTATHIONINE BETA-SYNTHASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;lyase#PC00144 Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887 GORGO|Ensembl=ENSGGOG00000000071.4|UniProtKB=G3QCW8 G3QCW8 CCDC91 PTHR35072:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 91 COILED-COIL DOMAIN-CONTAINING PROTEIN 91 Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;lysosomal transport#GO:0007041;post-Golgi vesicle-mediated transport#GO:0006892;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus subcompartment#GO:0098791 GORGO|Ensembl=ENSGGOG00000000734.3|UniProtKB=A0A2I2ZSZ9 A0A2I2ZSZ9 PTHR23316:SF64 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001573.3|UniProtKB=G3QGU2 G3QGU2 PRPF40B PTHR11864:SF1 PRE-MRNA-PROCESSING PROTEIN PRP40 PRE-MRNA-PROCESSING FACTOR 40 HOMOLOG B binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114 GORGO|Ensembl=ENSGGOG00000037430.1|UniProtKB=A0A2I2ZFD9 A0A2I2ZFD9 PTHR48014:SF19 SERINE/THREONINE-PROTEIN KINASE FRAY2 STE20-RELATED KINASE ADAPTER PROTEIN BETA molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 protein export from nucleus#GO:0006611;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;protein-containing complex#GO:0032991 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000013228.3|UniProtKB=G3RM62 G3RM62 DPP3 PTHR23422:SF11 DIPEPTIDYL PEPTIDASE III-RELATED DIPEPTIDYL PEPTIDASE 3 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000000453.3|UniProtKB=G3SE28 G3SE28 SECISBP2 PTHR13284:SF9 GH01354P SELENOCYSTEINE INSERTION SEQUENCE-BINDING PROTEIN 2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA 3'-UTR binding#GO:0003730;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;translational elongation#GO:0006414;metabolic process#GO:0008152;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005553.3|UniProtKB=A0A2I2YCZ6 A0A2I2YCZ6 SLIT1 PTHR45836:SF3 SLIT HOMOLOG SLIT HOMOLOG 1 PROTEIN carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102;binding#GO:0005488;heparin binding#GO:0008201;protein binding#GO:0005515 cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;taxis#GO:0042330;response to chemical#GO:0042221;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;locomotion#GO:0040011;chemotaxis#GO:0006935;system development#GO:0048731;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 GORGO|Ensembl=ENSGGOG00000000960.3|UniProtKB=G3QF81 G3QF81 MARK1 PTHR24346:SF21 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE MARK1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Gene=NDUFS3|UniProtKB=Q0MQG7 Q0MQG7 NDUFS3 PTHR10884:SF15 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000027143.2|UniProtKB=G3S113 G3S113 LOC101130023 PTHR24404:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 835 double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002517.3|UniProtKB=G3QJ94 G3QJ94 UBA2 PTHR10953:SF5 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 2 catalytic activity, acting on a protein#GO:0140096;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 GORGO|Ensembl=ENSGGOG00000026376.2|UniProtKB=G3SER5 G3SER5 ADTRP PTHR10989:SF17 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-DEPENDENT TFPI-REGULATING PROTEIN catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane raft#GO:0045121;caveola#GO:0005901;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000015249.3|UniProtKB=G3RGW8 G3RGW8 MAK PTHR24055:SF194 MITOGEN-ACTIVATED PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE MAK kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular response to stimulus#GO:0051716;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;intraciliary transport#GO:0042073;organelle assembly#GO:0070925;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;cell projection organization#GO:0030030;response to stimulus#GO:0050896;signaling#GO:0023052;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;cilium organization#GO:0044782 nucleus#GO:0005634;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000002389.3|UniProtKB=G3QIY0 G3QIY0 EEF1D PTHR11595:SF21 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-DELTA guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000027566.2|UniProtKB=G3S9P2 G3S9P2 PDPK1 PTHR24353:SF133 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell adhesion#GO:0007155;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Enkephalin release#P05913>PKA#P05972;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946 GORGO|Ensembl=ENSGGOG00000001582.3|UniProtKB=G3QGU8 G3QGU8 FMNL3 PTHR45857:SF3 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 3 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cell migration#GO:0016477;cell motility#GO:0048870;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000011608.3|UniProtKB=G3R7I1 G3R7I1 RAC3 PTHR24072:SF325 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection organization#GO:0030030;cell differentiation#GO:0030154;signaling#GO:0023052;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;Rac protein signal transduction#GO:0016601;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of developmental process#GO:0050793;regulation of cell motility#GO:2000145;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;system development#GO:0048731;intracellular signal transduction#GO:0035556;cortical cytoskeleton organization#GO:0030865;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;neuron differentiation#GO:0030182;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;cell development#GO:0048468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;axon guidance#GO:0007411;neuron projection guidance#GO:0097485;actin filament organization#GO:0007015;neurogenesis#GO:0022008;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 small GTPase#PC00208;G-protein#PC00020 EGF receptor signaling pathway#P00018>Rac#P00564;T cell activation#P00053>rac#P01324;Ras Pathway#P04393>Rac#P04559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Integrin signalling pathway#P00034>Rac#P00927;Huntington disease#P00029>Rac#P00775;FGF signaling pathway#P00021>Rac#P00645;Axon guidance mediated by netrin#P00009>Rac#P00366;Axon guidance mediated by semaphorins#P00007>Rac#P00340;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;VEGF signaling pathway#P00056>Rac#P01421;B cell activation#P00010>Rac#P00385;p38 MAPK pathway#P05918>Rac#P06021;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354 GORGO|Ensembl=ENSGGOG00000003394.3|UniProtKB=G3QLI3 G3QLI3 SMPD2 PTHR12393:SF8 SPHINGOMYELIN PHOSPHODIESTERASE RELATED SPHINGOMYELIN PHOSPHODIESTERASE 2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;lipase activity#GO:0016298;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sphingolipid catabolic process#GO:0030149;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;ceramide metabolic process#GO:0006672 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane raft#GO:0045121;endoplasmic reticulum#GO:0005783;membrane microdomain#GO:0098857;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;cell periphery#GO:0071944;caveola#GO:0005901;membrane#GO:0016020 phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000002954.3|UniProtKB=A0A2I2ZVF3 A0A2I2ZVF3 HSD17B13 PTHR24322:SF499 PKSB 17-BETA-HYDROXYSTEROID DEHYDROGENASE 13 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000004436.3|UniProtKB=G3RPV9 G3RPV9 WASF2 PTHR12902:SF6 WASP-1 ACTIN-BINDING PROTEIN WASF2 binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;organelle organization#GO:0006996;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043 cell leading edge#GO:0031252;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000038242.1|UniProtKB=G3RLJ6 G3RLJ6 GPR142 PTHR46272:SF1 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G PROTEIN-COUPLED RECEPTOR 142 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 GORGO|Ensembl=ENSGGOG00000043803.1|UniProtKB=A0A2I2ZS16 A0A2I2ZS16 PTHR23266:SF281 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-26 binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000007875.3|UniProtKB=G3QXY1 G3QXY1 PRR35 PTHR14678:SF2 PROLINE-RICH PROTEIN 35-RELATED PROLINE-RICH PROTEIN 35 GORGO|Ensembl=ENSGGOG00000037810.1|UniProtKB=A0A2I2ZS83 A0A2I2ZS83 SH3PXD2A PTHR15706:SF30 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;superoxide metabolic process#GO:0006801 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027450.2|UniProtKB=A0A2I2ZGE6 A0A2I2ZGE6 PTHR48099:SF15 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 GORGO|Ensembl=ENSGGOG00000028571.2|UniProtKB=G3RPL9 G3RPL9 PTHR10933:SF12 IMMUNOGLOBULIN-BINDING PROTEIN 1 IMMUNOGLOBULIN-BINDING PROTEIN 1 enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;TOR signaling#GO:0031929;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 p53 pathway by glucose deprivation#P04397>alpha4#P04646 GORGO|Ensembl=ENSGGOG00000043177.1|UniProtKB=G3RW36 G3RW36 RIBC1 PTHR14517:SF11 RIB43A-RELATED RIB43A-LIKE WITH COILED-COILS PROTEIN 1 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000006679.3|UniProtKB=G3QUX5 G3QUX5 PTHR10005:SF7 SKI ONCOGENE-RELATED SKI FAMILY TRANSCRIPTIONAL COREPRESSOR 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;negative regulation of BMP signaling pathway#GO:0030514;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;regulation of BMP signaling pathway#GO:0030510;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000014239.3|UniProtKB=G3REB5 G3REB5 GTF2H4 PTHR13152:SF0 TFIIH, POLYPEPTIDE 4 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 4 DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleotide-excision repair#GO:0006289;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription regulator complex#GO:0005667;transcription factor TFIIH core complex#GO:0000439;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIH complex#P00664;Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392 GORGO|Ensembl=ENSGGOG00000010295.3|UniProtKB=G3R470 G3R470 DGKQ PTHR11255:SF125 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE THETA transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 membrane#GO:0016020;cellular anatomical structure#GO:0110165 kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012686.3|UniProtKB=G3RAB4 G3RAB4 ODR4 PTHR33966:SF1 PROTEIN ODR-4 HOMOLOG PROTEIN ODR-4 HOMOLOG macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179 GORGO|Ensembl=ENSGGOG00000011577.3|UniProtKB=G3SFL6 G3SFL6 ART3 PTHR10339:SF4 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 3 pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000027583.2|UniProtKB=G3SH61 G3SH61 MESD PTHR17600:SF3 MESODERM DEVELOPMENT CANDIDATE 2 LRP CHAPERONE MESD signaling receptor binding#GO:0005102;binding#GO:0005488;lipoprotein particle receptor binding#GO:0070325;protein binding#GO:0005515 GORGO|Ensembl=ENSGGOG00000034949.2|UniProtKB=G3SKS6 G3SKS6 DENND6A PTHR13677:SF1 LD41638P PROTEIN DENND6A enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708 GORGO|Ensembl=ENSGGOG00000037760.1|UniProtKB=A0A2I2YUA6 A0A2I2YUA6 CEBPZOS PTHR38001:SF1 PROTEIN CEBPZOS PROTEIN CEBPZOS GORGO|Ensembl=ENSGGOG00000004167.4|UniProtKB=G3QNI1 G3QNI1 WWP2 PTHR11254:SF396 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;DNA-binding transcription factor binding#GO:0140297;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription factor binding#GO:0008134;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of transmembrane transport#GO:0034762;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of monoatomic ion transport#GO:0043269;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 GORGO|Ensembl=ENSGGOG00000034923.2|UniProtKB=G3SKF0 G3SKF0 PTHR23004:SF9 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2C microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000037636.1|UniProtKB=A0A2I2Y704 A0A2I2Y704 CLDN12 PTHR16703:SF3 CLAUDIN-12 CLAUDIN-12 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000013836.3|UniProtKB=A0A2I2YX17 A0A2I2YX17 AIPL1 PTHR11242:SF2 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED ARYL-HYDROCARBON-INTERACTING PROTEIN-LIKE 1 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000037284.1|UniProtKB=A0A2I2ZEC8 A0A2I2ZEC8 PTHR24381:SF319 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 699 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000013808.3|UniProtKB=G3RD74 G3RD74 CRLS1 PTHR14269:SF60 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED CARDIOLIPIN SYNTHASE (CMP-FORMING) transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 organophosphate biosynthetic process#GO:0090407;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;phosphatidylglycerol biosynthetic process#GO:0006655;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000043382.1|UniProtKB=A1YF15 A1YF15 ETV3 PTHR11849:SF30 ETS ETS TRANSLOCATION VARIANT 3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000013846.2|UniProtKB=G3RDA8 G3RDA8 THAP11 PTHR22794:SF2 THAP DOMAIN PROTEIN 11 THAP DOMAIN-CONTAINING PROTEIN 11 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000013850.3|UniProtKB=G3RDB7 G3RDB7 DCST2 PTHR21041:SF6 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DC-STAMP DOMAIN-CONTAINING PROTEIN 2 cell-cell recognition#GO:0009988;cell recognition#GO:0008037;sexual reproduction#GO:0019953;sperm-egg recognition#GO:0035036;reproductive process#GO:0022414;fertilization#GO:0009566;cellular process#GO:0009987;single fertilization#GO:0007338 GORGO|Ensembl=ENSGGOG00000016087.3|UniProtKB=A0A2I2YUC8 A0A2I2YUC8 TCP11 PTHR12832:SF14 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11 HOMOLOG signaling#GO:0023052;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;response to stimulus#GO:0050896;regulation of reproductive process#GO:2000241;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of cell development#GO:0060284;cell communication#GO:0007154;regulation of cell differentiation#GO:0045595 secretory vesicle#GO:0099503;cytoplasm#GO:0005737;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;acrosomal vesicle#GO:0001669;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000013260.3|UniProtKB=G3SA97 G3SA97 MME PTHR11733:SF114 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000042381.1|UniProtKB=A0A2I2Z6U4 A0A2I2Z6U4 LOC101128506 PTHR10556:SF57 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 1 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 regulation of biological quality#GO:0065008;steroid biosynthetic process#GO:0006694;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;hormone biosynthetic process#GO:0042446;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;primary metabolic process#GO:0044238 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007482.3|UniProtKB=A0A2I2Y6L3 A0A2I2Y6L3 DARS1 PTHR43450:SF1 ASPARTYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 catalytic complex#GO:1902494;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000011448.3|UniProtKB=G3R736 G3R736 ZSCAN21 PTHR23226:SF10 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 21 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000000514.3|UniProtKB=G3QE21 G3QE21 EIF2B2 PTHR45859:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT BETA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;guanyl-nucleotide exchange factor activity#GO:0005085;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000000968.3|UniProtKB=G3RUJ2 G3RUJ2 ABCF1 PTHR19211:SF130 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1 small molecule binding#GO:0036094;ATP binding#GO:0005524;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000009641.3|UniProtKB=G3R2G5 G3R2G5 PFN3 PTHR13936:SF2 PROFILIN PROFILIN-3 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of actin filament bundle assembly#GO:0032231;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;regulation of actin filament polymerization#GO:0030833;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 GORGO|Ensembl=ENSGGOG00000000482.3|UniProtKB=G3QDZ1 G3QDZ1 ABCB9 PTHR24221:SF242 ATP-BINDING CASSETTE SUB-FAMILY B ABC-TYPE OLIGOPEPTIDE TRANSPORTER ABCB9 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000004852.3|UniProtKB=G3QQ93 G3QQ93 B3GALT9 PTHR11214:SF29 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 9 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000001867.3|UniProtKB=A0A2I2YMS9 A0A2I2YMS9 MTREX PTHR12131:SF7 ATP-DEPENDENT RNA AND DNA HELICASE EXOSOME RNA HELICASE MTR4 helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;cellular component biogenesis#GO:0044085;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000005836.3|UniProtKB=A0A2I2ZEB4 A0A2I2ZEB4 RPN2 PTHR12640:SF0 RIBOPHORIN II DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000007971.3|UniProtKB=G3QY68 G3QY68 TUFT1 PTHR23171:SF4 GDOWN1 TUFTELIN nuclear protein-containing complex#GO:0140513;sarcomere#GO:0030017;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;I band#GO:0031674;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II, core complex#GO:0005665;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000004341.3|UniProtKB=G3QNY2 G3QNY2 GSDMC PTHR16399:SF21 GASDERMIN GASDERMIN-C phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;inflammatory response#GO:0006954;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;defense response#GO:0006952;response to external stimulus#GO:0009605 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000038348.1|UniProtKB=A0A2I2Z977 A0A2I2Z977 LIN52 PTHR31489:SF2 LIN52 FAMILY MEMBER PROTEIN LIN-52 HOMOLOG GORGO|Ensembl=ENSGGOG00000038168.1|UniProtKB=Q9N2B1 Q9N2B1 HRH1 PTHR24247:SF223 5-HYDROXYTRYPTAMINE RECEPTOR HISTAMINE H1 RECEPTOR G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;acetylcholine receptor activity#GO:0015464;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Histamine H1 receptor mediated signaling pathway#P04385>H1#P04485;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 GORGO|Gene=S100A15A|UniProtKB=A7K6Y8 A7K6Y8 S100A15A PTHR11639:SF29 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A15A ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular process#GO:0009987;cell motility#GO:0048870;cell migration#GO:0016477;endothelial cell migration#GO:0043542 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000004387.3|UniProtKB=G3QP19 G3QP19 VEZF1 PTHR24390:SF213 ZINC FINGER PROTEIN MYC-ASSOCIATED ZINC FINGER PROTEIN-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014195.3|UniProtKB=G3RE78 G3RE78 YLPM1 PTHR13413:SF0 YLP MOTIF CONTAINING PROTEIN NUCLEAR PROTEIN ZAP YLP MOTIF-CONTAINING PROTEIN 1 regulation of telomere maintenance#GO:0032204;regulation of chromosome organization#GO:0033044;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000011449.3|UniProtKB=G3R738 G3R738 GLT8D1 PTHR13778:SF3 GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009573.3|UniProtKB=G3R2A3 G3R2A3 CAVIN3 PTHR15240:SF2 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 3 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 membrane raft#GO:0045121;caveola#GO:0005901;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000001382.3|UniProtKB=G3QGB1 G3QGB1 LRIT3 PTHR24366:SF57 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000015081.3|UniProtKB=G3QKA0 G3QKA0 FGFR3 PTHR24416:SF505 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 3 transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;signaling receptor activity#GO:0038023;fibroblast growth factor binding#GO:0017134;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 GORGO|Ensembl=ENSGGOG00000004456.3|UniProtKB=A0A2I2YI79 A0A2I2YI79 SLC5A2 PTHR11819:SF145 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 2 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;sugar transmembrane transporter activity#GO:0051119;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144 carbohydrate transmembrane transport#GO:0034219;multicellular organismal process#GO:0032501;import across plasma membrane#GO:0098739;renal system process#GO:0003014;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;renal absorption#GO:0070293;localization#GO:0051179;system process#GO:0003008;transport#GO:0006810;carbohydrate transport#GO:0008643 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000013821.3|UniProtKB=G3RD83 G3RD83 PMEPA1 PTHR16514:SF5 LOW DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING 4A PROTEIN TMEPAI protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015962.3|UniProtKB=G3RST5 G3RST5 CROT PTHR22589:SF67 CARNITINE O-ACYLTRANSFERASE PEROXISOMAL CARNITINE O-OCTANOYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002714.3|UniProtKB=G3SCG0 G3SCG0 FAU PTHR12650:SF37 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI 40S RIBOSOMAL PROTEIN S30 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000022596.2|UniProtKB=G3SE09 G3SE09 PTHR24248:SF54 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-1 ADRENERGIC RECEPTOR G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;vasodilation#GO:0042311;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;cell communication#GO:0007154;regulation of biological quality#GO:0065008;adrenergic receptor signaling pathway#GO:0071875;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;signal transduction#GO:0007165;cellular process#GO:0009987;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of anatomical structure size#GO:0090066;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Beta1 adrenergic receptor signaling pathway#P04377>Beta1#P04433 GORGO|Ensembl=ENSGGOG00000015829.3|UniProtKB=A0A2I2YDI8 A0A2I2YDI8 ZNF74 PTHR24377:SF336 IP01015P-RELATED ZINC FINGER PROTEIN 74 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004627.3|UniProtKB=G3QPP6 G3QPP6 SPTBN4 PTHR11915:SF232 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 4 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;anatomical structure development#GO:0048856;system development#GO:0048731;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000006981.3|UniProtKB=G3SBZ5 G3SBZ5 MPP3 PTHR23122:SF33 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 3 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037327.1|UniProtKB=G3RUH9 G3RUH9 LOC101140122 PTHR45810:SF10 HISTONE H3.2 HISTONE H3 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 GORGO|Ensembl=ENSGGOG00000025371.2|UniProtKB=G3S6U9 G3S6U9 BBLN PTHR34344:SF1 UPF0184 PROTEIN C9ORF16 BUBLIN COILED-COIL PROTEIN supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;intermediate filament bundle assembly#GO:0045110;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;intermediate filament cytoskeleton organization#GO:0045104;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000025254.3|UniProtKB=G3S3M3 G3S3M3 ITGA4 PTHR23220:SF78 INTEGRIN ALPHA INTEGRIN ALPHA-4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 integrin complex#GO:0008305;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 integrin#PC00126;cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000015121.3|UniProtKB=G3RGL0 G3RGL0 DPPA4 PTHR16073:SF8 DCR DOMAIN-CONTAINING PROTEIN DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 4 chromatin binding#GO:0003682;binding#GO:0005488 developmental process#GO:0032502;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000003647.3|UniProtKB=G3S6A3 G3S6A3 CCDC24 PTHR28601:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 24 COILED-COIL DOMAIN-CONTAINING PROTEIN 24 GORGO|Ensembl=ENSGGOG00000012258.3|UniProtKB=G3R980 G3R980 C4BPA PTHR19325:SF551 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING C4B-BINDING PROTEIN ALPHA CHAIN leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;T cell mediated immunity#GO:0002456;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 complement component#PC00078;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000379.3|UniProtKB=A0A2I2YL32 A0A2I2YL32 SLC6A11 PTHR11616:SF124 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 3 secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370 sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000008793.3|UniProtKB=G3R0B4 G3R0B4 PTHR48424:SF3 DYNEIN LIGHT CHAIN-RELATED DYNEIN LIGHT CHAIN Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000010472.3|UniProtKB=G3R4K6 G3R4K6 TLCD2 PTHR13439:SF2 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 2 chemical homeostasis#GO:0048878;regulation of membrane lipid distribution#GO:0097035;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;membrane assembly#GO:0071709;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;homeostatic process#GO:0042592;membrane organization#GO:0061024;cellular component assembly#GO:0022607 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012818.3|UniProtKB=G3RAN3 G3RAN3 PALB2 PTHR14662:SF2 PARTNER AND LOCALIZER OF BRCA2 PARTNER AND LOCALIZER OF BRCA2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000006792.3|UniProtKB=G3S663 G3S663 MEIS2 PTHR11850:SF47 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS2 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;eye development#GO:0001654;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;head development#GO:0060322;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;embryonic pattern specification#GO:0009880;sensory system development#GO:0048880 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000011558.3|UniProtKB=G3R7D9 G3R7D9 IKZF4 PTHR24404:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN EOS sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000026388.2|UniProtKB=A0A2I2Z9Z7 A0A2I2Z9Z7 PTHR13338:SF7 UPF0240 PROTEIN NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 4 cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000026412.2|UniProtKB=A0A2I2YF53 A0A2I2YF53 DPF2 PTHR45888:SF7 HL01030P-RELATED ZINC FINGER PROTEIN UBI-D4 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000006277.3|UniProtKB=G3QTV4 G3QTV4 PTHR13058:SF27 THREE PRIME REPAIR EXONUCLEASE 1, 2 THREE-PRIME REPAIR EXONUCLEASE 1 hydrolase activity#GO:0016787;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 DNA catabolic process#GO:0006308;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000027658.2|UniProtKB=A0A2I2YI08 A0A2I2YI08 PTHR11875:SF119 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 4 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010035.3|UniProtKB=G3R3G5 G3R3G5 FNDC5 PTHR14470:SF5 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 5 regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of developmental process#GO:0051094;positive regulation of fat cell differentiation#GO:0045600;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000044140.1|UniProtKB=A0A2I2Z3T4 A0A2I2Z3T4 PTHR23299:SF18 METALLOTHIONEIN METALLOTHIONEIN-3 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;response to stimulus#GO:0050896;inorganic ion homeostasis#GO:0098771;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;monoatomic ion homeostasis#GO:0050801;response to stress#GO:0006950;detoxification of inorganic compound#GO:0061687;detoxification#GO:0098754;regulation of ERK1 and ERK2 cascade#GO:0070372;response to chemical#GO:0042221;chemical homeostasis#GO:0048878;regulation of MAPK cascade#GO:0043408;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;homeostatic process#GO:0042592;positive regulation of cell communication#GO:0010647;response to toxic substance#GO:0009636;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;response to metal ion#GO:0010038;response to cadmium ion#GO:0046686;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;positive regulation of MAPK cascade#GO:0043410 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010142.3|UniProtKB=G3R3R4 G3R3R4 AIP PTHR11242:SF3 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED AH RECEPTOR-INTERACTING PROTEIN protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000013285.3|UniProtKB=G3RXA7 G3RXA7 AKAP11 PTHR10226:SF3 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN 11 protein binding#GO:0005515;protein kinase A binding#GO:0051018;binding#GO:0005488 intracellular protein localization#GO:0008104;cell communication#GO:0007154;localization#GO:0051179;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027754.2|UniProtKB=A0A2I2ZJ05 A0A2I2ZJ05 LOC101131692 PTHR12035:SF146 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 13 ion binding#GO:0043167;carbohydrate derivative binding#GO:0097367;carboxylic acid binding#GO:0031406;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;organic acid binding#GO:0043177 cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000016661.3|UniProtKB=G3RKI5 G3RKI5 TRHR PTHR46061:SF2 THYROTROPIN-RELEASING HORMONE RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH Receptor#P04580 GORGO|Ensembl=ENSGGOG00000005130.3|UniProtKB=G3QQZ3 G3QQZ3 MYCN PTHR45851:SF2 MYC PROTO-ONCOGENE N-MYC PROTO-ONCOGENE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 GORGO|Ensembl=ENSGGOG00000008885.3|UniProtKB=G3R0K1 G3R0K1 RFTN1 PTHR17601:SF3 RAFTLIN-RELATED RAFTLIN GORGO|Ensembl=ENSGGOG00000039980.1|UniProtKB=A0A2I2YEL1 A0A2I2YEL1 PTHR45715:SF13 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED ATP6V1E1 proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810 protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949 GORGO|Ensembl=ENSGGOG00000001762.3|UniProtKB=A0A2I2YSI1 A0A2I2YSI1 LSM14A PTHR13586:SF2 SCD6 PROTEIN-RELATED PROTEIN LSM14 HOMOLOG A binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;P-body assembly#GO:0033962;cellular process#GO:0009987;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000039997.1|UniProtKB=A0A2I2Z8C6 A0A2I2Z8C6 NFYA PTHR12632:SF122 TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT ALPHA transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 GORGO|Ensembl=ENSGGOG00000012575.3|UniProtKB=G3RZP6 G3RZP6 PTHR15583:SF13 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR A transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to cytokine#GO:0034097;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;positive regulation of metabolic process#GO:0009893;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037403.1|UniProtKB=G3QES9 G3QES9 PTHR11256:SF11 BCL-2 RELATED APOPTOSIS REGULATOR BCL-2 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;response to stress#GO:0006950;organelle organization#GO:0006996;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Apoptosis signaling pathway#P00006>Bcl-2#P00270;Oxidative stress response#P00046>Bcl-2#P01123;CCKR signaling map#P06959>BCL2#P07059 GORGO|Ensembl=ENSGGOG00000011237.3|UniProtKB=G3QJD6 G3QJD6 ACTR1A PTHR11937:SF370 ACTIN ALPHA-CENTRACTIN cytoskeletal adaptor activity#GO:0008093;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;structural constituent of cytoskeleton#GO:0005200;protein-membrane adaptor activity#GO:0043495;structural molecule activity#GO:0005198 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;nuclear migration#GO:0007097;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 GORGO|Ensembl=ENSGGOG00000011482.3|UniProtKB=G3R769 G3R769 DEF8 PTHR12326:SF3 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN DIFFERENTIALLY EXPRESSED IN FDCP 8 HOMOLOG GORGO|Ensembl=ENSGGOG00000028273.2|UniProtKB=A0A2I2ZJG3 A0A2I2ZJG3 PTHR23158:SF55 MELANOMA INHIBITORY ACTIVITY-RELATED MIA SH3 DOMAIN ER EXPORT FACTOR 2 intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;secretion by cell#GO:0032940;protein transport#GO:0015031;localization#GO:0051179;protein secretion#GO:0009306;secretion#GO:0046903;cellular localization#GO:0051641;export from cell#GO:0140352;protein localization to extracellular region#GO:0071692 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013278.3|UniProtKB=G3SCK3 G3SCK3 CLRN3 PTHR31548:SF3 CLARIN CLARIN-3 GORGO|Ensembl=ENSGGOG00000040724.1|UniProtKB=A0A2I2Y4W5 A0A2I2Y4W5 HHAT PTHR13285:SF20 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE HHAT palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000016684.3|UniProtKB=G3RKK9 G3RKK9 NHLRC1 PTHR24104:SF64 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED E3 UBIQUITIN-PROTEIN LIGASE NHLRC1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000028575.2|UniProtKB=G3RWE0 G3RWE0 BTBD18 PTHR47639:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 18 BTB_POZ DOMAIN-CONTAINING PROTEIN 18 spermatogenesis#GO:0007283;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;male gamete generation#GO:0048232;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000027919.2|UniProtKB=G3RRY7 G3RRY7 CLEC2L PTHR47498:SF1 C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER L C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER L GORGO|Ensembl=ENSGGOG00000000775.3|UniProtKB=G3QER4 G3QER4 FGR PTHR24418:SF224 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FGR protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;non-membrane spanning protein tyrosine kinase activity#GO:0004715;signaling receptor binding#GO:0005102;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230 GORGO|Ensembl=ENSGGOG00000001751.3|UniProtKB=G3QH98 G3QH98 PTHR23226:SF313 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 93 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022413.2|UniProtKB=G3RY62 G3RY62 UNG PTHR11264:SF0 URACIL-DNA GLYCOSYLASE URACIL-DNA GLYCOSYLASE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA N-glycosylase activity#GO:0019104;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 DNA glycosylase#PC00010 GORGO|Ensembl=ENSGGOG00000000678.3|UniProtKB=G3QEH3 G3QEH3 RP1L1 PTHR23005:SF3 RETINITIS PIGMENTOSA 1 PROTEIN RETINITIS PIGMENTOSA 1-LIKE 1 PROTEIN cellular process#GO:0009987;cell projection assembly#GO:0030031;sensory system development#GO:0048880;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;retina development in camera-type eye#GO:0060041;cytoskeleton organization#GO:0007010;anatomical structure homeostasis#GO:0060249;cellular component assembly#GO:0022607;neuron differentiation#GO:0030182;microtubule-based process#GO:0007017;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;eye development#GO:0001654;cilium organization#GO:0044782;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031;neurogenesis#GO:0022008;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;visual system development#GO:0150063;homeostatic process#GO:0042592;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;camera-type eye development#GO:0043010;tissue homeostasis#GO:0001894;axoneme assembly#GO:0035082;system development#GO:0048731;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;retina homeostasis#GO:0001895 ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;ciliary transition zone#GO:0035869;cilium#GO:0005929;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006077.3|UniProtKB=G3QTD3 G3QTD3 BCL2A1 PTHR11256:SF10 BCL-2 RELATED BCL-2-RELATED PROTEIN A1 channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 mitochondrial fusion#GO:0008053;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of cellular process#GO:0050794;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of cellular process#GO:0048522;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;signaling#GO:0023052;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739 Apoptosis signaling pathway#P00006>A1#P00283 GORGO|Ensembl=ENSGGOG00000002718.3|UniProtKB=G3QJS6 G3QJS6 SYVN1 PTHR22763:SF196 RING ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000036921.1|UniProtKB=A0A2I2YS27 A0A2I2YS27 OR2H1 PTHR26453:SF323 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2H1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013309.3|UniProtKB=G3RBW4 G3RBW4 PRH2 PTHR23203:SF19 PROLINE-RICH PROTEIN SALIVARY ACIDIC PROLINE-RICH PHOSPHOPROTEIN 1_2 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000014017.3|UniProtKB=G3RDQ6 G3RDQ6 C2H3orf22 PTHR37875:SF1 HYPOTHETICAL PROTEIN LOC685964 SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 22 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000025637.2|UniProtKB=G3RTL5 G3RTL5 LIG3 PTHR45674:SF20 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 3 ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA ligase#PC00012 GORGO|Ensembl=ENSGGOG00000034852.2|UniProtKB=G3SKQ3 G3SKQ3 RUNDC3B PTHR46251:SF1 RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 RUN DOMAIN-CONTAINING PROTEIN 3B GORGO|Ensembl=ENSGGOG00000025895.2|UniProtKB=G3SJ08 G3SJ08 S100Z PTHR11639:SF72 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-Z calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000004353.3|UniProtKB=G3QNY9 G3QNY9 SMPX PTHR17416:SF0 SMALL MUSCULAR PROTEIN SMALL MUSCULAR PROTEIN cell junction#GO:0030054;sarcomere#GO:0030017;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;M band#GO:0031430;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;myofibril#GO:0030016;A band#GO:0031672;cell-substrate junction#GO:0030055;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013800.3|UniProtKB=G3RD72 G3RD72 INSRR PTHR24416:SF338 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN RECEPTOR-RELATED PROTEIN transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888 response to endogenous stimulus#GO:0009719;carbohydrate homeostasis#GO:0033500;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;positive regulation of signaling#GO:0023056;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;chemical homeostasis#GO:0048878;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;regulation of JNK cascade#GO:0046328;glucose homeostasis#GO:0042593;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;homeostatic process#GO:0042592;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of cellular process#GO:0048522;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;response to peptide hormone#GO:0043434;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410 axon#GO:0030424;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;signaling receptor complex#GO:0043235;protein kinase complex#GO:1902911;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885 GORGO|Gene=ERVW-1|UniProtKB=P61561 P61561 ERVW-1 PTHR10424:SF48 VIRAL ENVELOPE PROTEIN SYNCYTIN-1 muscle cell differentiation#GO:0042692;cellular process#GO:0009987;myoblast fusion#GO:0007520;cell differentiation#GO:0030154;muscle structure development#GO:0061061;developmental process#GO:0032502;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;striated muscle cell differentiation#GO:0051146;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000039088.1|UniProtKB=A0A2I2YG66 A0A2I2YG66 ZNF689 PTHR24381:SF297 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 785 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000003257.3|UniProtKB=G3QL58 G3QL58 TMEM54 PTHR31258:SF2 KERATINOCYTE-ASSOCIATED PROTEIN 3 TRANSMEMBRANE PROTEIN 54 GORGO|Ensembl=ENSGGOG00000004688.3|UniProtKB=G3QPU0 G3QPU0 ZNF274 PTHR23226:SF93 ZINC FINGER AND SCAN DOMAIN-CONTAINING NEUROTROPHIN RECEPTOR-INTERACTING FACTOR HOMOLOG sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009470.3|UniProtKB=A0A2I2Y410 A0A2I2Y410 GIT2 PTHR46097:SF4 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT2 enzyme binding#GO:0019899;binding#GO:0005488;molecular function activator activity#GO:0140677;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;system development#GO:0048731;localization#GO:0051179;cellular localization#GO:0051641;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of small GTPase mediated signal transduction#GO:0051056;multicellular organism development#GO:0007275;animal organ development#GO:0048513;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;head development#GO:0060322;nervous system development#GO:0007399;brain development#GO:0007420;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 GORGO|Ensembl=ENSGGOG00000008643.3|UniProtKB=G3RUA6 G3RUA6 PTHR10366:SF241 NAD DEPENDENT EPIMERASE/DEHYDRATASE SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E MEMBER 2-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 dehydratase#PC00091;lyase#PC00144;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002066.3|UniProtKB=G3RTY5 G3RTY5 ARL5A PTHR11711:SF147 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5A purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000042195.1|UniProtKB=A0A2I2ZUK6 A0A2I2ZUK6 PTHR11910:SF1 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT OSCP, MITOCHONDRIAL transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000010836.3|UniProtKB=G3R5I7 G3R5I7 EFEMP2 PTHR24034:SF96 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 2 extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;supramolecular fiber organization#GO:0097435;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000024865.2|UniProtKB=G3RW22 G3RW22 ERGIC2 PTHR10984:SF30 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 2 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890 vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;COPII-coated ER to Golgi transport vesicle#GO:0030134 GORGO|Ensembl=ENSGGOG00000017118.3|UniProtKB=G3RLP7 G3RLP7 APH1A PTHR12889:SF3 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;protein maturation#GO:0051604;signal transduction#GO:0007165;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cell communication#GO:0007154;protein metabolic process#GO:0019538;proteolysis#GO:0006508 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>Aph-1#P00091;Notch signaling pathway#P00045>Aph-1#P01109;Alzheimer disease-presenilin pathway#P00004>Aph-1#P00170 GORGO|Ensembl=ENSGGOG00000009851.3|UniProtKB=G3R312 G3R312 IGSF21 PTHR23277:SF121 NECTIN-RELATED IMMUNOGLOBULIN SUPERFAMILY MEMBER 21 cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 trans-synaptic signaling#GO:0099537;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;homophilic cell-cell adhesion#GO:0007156;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 synaptic membrane#GO:0097060;adherens junction#GO:0005912;cell junction#GO:0030054;cell periphery#GO:0071944;presynapse#GO:0098793;cell-cell junction#GO:0005911;membrane#GO:0016020;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;anchoring junction#GO:0070161;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000003525.3|UniProtKB=G3RTU6 G3RTU6 NUAK2 PTHR24343:SF133 SERINE/THREONINE KINASE NUAK FAMILY SNF1-LIKE KINASE 2 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 response to stress#GO:0006950;response to nutrient levels#GO:0031667;response to starvation#GO:0042594;cellular response to glucose starvation#GO:0042149;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to starvation#GO:0009267;cellular response to stress#GO:0033554;cellular response to nutrient levels#GO:0031669 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000012021.3|UniProtKB=G3R8L9 G3R8L9 MLIP PTHR31514:SF1 MUSCULAR LMNA-INTERACTING PROTEIN MLIP MUSCULAR LMNA-INTERACTING PROTEIN GORGO|Ensembl=ENSGGOG00000014946.3|UniProtKB=G3RG42 G3RG42 PTHR20937:SF6 IP14615P MESODERM POSTERIOR PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;mesoderm formation#GO:0001707;epithelium development#GO:0060429;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;mesoderm morphogenesis#GO:0048332;heart morphogenesis#GO:0003007;mesoderm development#GO:0007498;animal organ development#GO:0048513;anterior/posterior axis specification#GO:0009948;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anatomical structure formation involved in morphogenesis#GO:0048646;anterior/posterior pattern specification#GO:0009952;heart development#GO:0007507;embryo development#GO:0009790;embryonic pattern specification#GO:0009880;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;formation of primary germ layer#GO:0001704;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;gastrulation#GO:0007369;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000008270.3|UniProtKB=G3RN61 G3RN61 CES4A PTHR11559:SF254 CARBOXYLESTERASE CARBOXYLESTERASE 4A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000012104.3|UniProtKB=G3R8T3 G3R8T3 C3H4orf46 PTHR31641:SF2 RENAL CANCER DIFFERENTIATION GENE 1 PROTEIN RENAL CANCER DIFFERENTIATION GENE 1 PROTEIN GORGO|Ensembl=ENSGGOG00000040599.1|UniProtKB=A0A2I2ZRI3 A0A2I2ZRI3 PTHR23267:SF402 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-39-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000041492.1|UniProtKB=G3R1B6 G3R1B6 LOC101149907 PTHR48018:SF25 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5B17 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040798.1|UniProtKB=A0A2I2Y7B4 A0A2I2Y7B4 PTHR46315:SF3 SPERMINE SYNTHASE PABS DOMAIN-CONTAINING PROTEIN transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596 GORGO|Ensembl=ENSGGOG00000007974.3|UniProtKB=A0A2I2YXZ0 A0A2I2YXZ0 AIMP2 PTHR13438:SF2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005499.3|UniProtKB=A0A2I2ZXZ2 A0A2I2ZXZ2 PTHR28342:SF3 MONOOXYGENASE P33MONOX-RELATED MONOOXYGENASE P33MONOX cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000004846.3|UniProtKB=G3QQ87 G3QQ87 PITX1 PTHR45882:SF1 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>PITX#P06722 GORGO|Ensembl=ENSGGOG00000027830.2|UniProtKB=G3RY92 G3RY92 PTHR18860:SF88 14-3-3 PROTEIN 14-3-3 DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003657.3|UniProtKB=G3QM69 G3QM69 GK5 PTHR10196:SF68 SUGAR KINASE GLYCEROL KINASE 5 phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;acylglycerol metabolic process#GO:0006639;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;organophosphate biosynthetic process#GO:0090407 cytosol#GO:0005829;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000042627.1|UniProtKB=A0A2I2ZTG4 A0A2I2ZTG4 ZBED2 PTHR35827:SF1 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 3 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cell differentiation#GO:0045597;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;regulation of epithelial cell differentiation#GO:0030856;negative regulation of macromolecule biosynthetic process#GO:0010558 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000006329.3|UniProtKB=A0A2I2YVF4 A0A2I2YVF4 RALGAPA2 PTHR10063:SF2 TUBERIN RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-2 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000043342.1|UniProtKB=A0A2I2YLJ6 A0A2I2YLJ6 PTHR12022:SF12 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 7 electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275;catalytic complex#GO:1902494 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000014742.3|UniProtKB=G3RFM5 G3RFM5 UBA6 PTHR10953:SF186 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 6 sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 GORGO|Ensembl=ENSGGOG00000007198.3|UniProtKB=A0A2I2YE12 A0A2I2YE12 FAM114A2 PTHR12842:SF3 FI01459P PROTEIN FAM114A2 GORGO|Ensembl=ENSGGOG00000005154.3|UniProtKB=G3RMU3 G3RMU3 SLC6A2 PTHR11616:SF336 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NORADRENALINE TRANSPORTER symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081 cellular localization#GO:0051641;transmembrane transport#GO:0055085;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;organic hydroxy compound transport#GO:0015850;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;import into cell#GO:0098657;establishment of localization#GO:0051234;amino acid transport#GO:0006865;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic cation transmembrane transport#GO:0098655;nitrogen compound transport#GO:0071705;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, dopaminergic#GO:0001963;sodium ion transmembrane transport#GO:0035725;establishment of localization in cell#GO:0051649 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;presynapse#GO:0098793;membrane#GO:0016020;presynaptic membrane#GO:0042734;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;axon#GO:0030424;cell body#GO:0044297;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;synapse#GO:0045202 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>NET#P00064 GORGO|Ensembl=ENSGGOG00000023462.2|UniProtKB=G3S1Q8 G3S1Q8 PTHR11711:SF119 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4C heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 endocytic recycling#GO:0032456;localization within membrane#GO:0051668;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 GORGO|Ensembl=ENSGGOG00000016697.3|UniProtKB=A0A2I2Z098 A0A2I2Z098 DPYSL5 PTHR11647:SF58 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 5 dihydropyrimidinase activity#GO:0004157;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRAM#P00330;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 GORGO|Ensembl=ENSGGOG00000037565.1|UniProtKB=G3S5E8 G3S5E8 LOC129529069 PTHR23097:SF116 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6B transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004155.3|UniProtKB=G3QNG1 G3QNG1 SYS1 PTHR12952:SF0 SYS1 PROTEIN SYS1 HOMOLOG Golgi to endosome transport#GO:0006895;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;cytosolic transport#GO:0016482;Golgi to plasma membrane protein transport#GO:0043001;protein localization to organelle#GO:0033365;Golgi to plasma membrane transport#GO:0006893;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;protein localization to Golgi apparatus#GO:0034067;protein localization to cell periphery#GO:1990778;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006692.3|UniProtKB=G3QUZ3 G3QUZ3 ESF1 PTHR12202:SF0 ESF1 HOMOLOG ESF1 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000014457.3|UniProtKB=G3REV7 G3REV7 ITGB2 PTHR10082:SF15 INTEGRIN BETA SUBUNIT INTEGRIN BETA-2 binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;peptide binding#GO:0042277;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;cell adhesion molecule binding#GO:0050839;integrin binding#GO:0005178 biological regulation#GO:0065007;cell migration#GO:0016477;cell adhesion mediated by integrin#GO:0033627;leukocyte migration#GO:0050900;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;cell chemotaxis#GO:0060326;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;signal transduction#GO:0007165;leukocyte cell-cell adhesion#GO:0007159;cell-cell adhesion#GO:0098609;granulocyte migration#GO:0097530;response to chemical#GO:0042221;neutrophil migration#GO:1990266;taxis#GO:0042330;cell surface receptor signaling pathway#GO:0007166;neutrophil chemotaxis#GO:0030593;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887 cell junction#GO:0030054;integrin complex#GO:0008305;anchoring junction#GO:0070161;signaling receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 integrin#PC00126 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin beta#P00931 GORGO|Ensembl=ENSGGOG00000027092.2|UniProtKB=G3SDB3 G3SDB3 ARID4A PTHR13964:SF26 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000008431.3|UniProtKB=G3QZD1 G3QZD1 ID3 PTHR11723:SF16 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-3 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Id3#P06711 GORGO|Ensembl=ENSGGOG00000004670.3|UniProtKB=A0A2I2YHE3 A0A2I2YHE3 PTHR18929:SF257 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A3 intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell surface#GO:0009986;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000007926.3|UniProtKB=A0A2I2Z8E6 A0A2I2Z8E6 HEXIM2 PTHR13469:SF3 HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 PROTEIN HEXIM2 molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;snRNA binding#GO:0017069;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000037165.1|UniProtKB=A0A2I2Y1S7 A0A2I2Y1S7 PTHR43247:SF4 PHOSPHOSERINE AMINOTRANSFERASE PHOSPHOSERINE AMINOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;transaminase activity#GO:0008483;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000014480.3|UniProtKB=G3SGT7 G3SGT7 LOC101126399 PTHR11417:SF70 SOMATOTROPIN,PROLACTIN CHORIONIC SOMATOMAMMOTROPIN HORMONE 1 protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;binding#GO:0005488;hormone receptor binding#GO:0051427;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 cell surface receptor signaling pathway#GO:0007166;animal organ development#GO:0048513;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;cellular response to nitrogen compound#GO:1901699;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;regulation of receptor signaling pathway via STAT#GO:1904892 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000002208.3|UniProtKB=G3QIG3 G3QIG3 TBX21 PTHR11267:SF125 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX21 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 leukocyte migration#GO:0050900;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;lymphocyte migration#GO:0072676;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;immune system process#GO:0002376;mononuclear cell migration#GO:0071674;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;cell motility#GO:0048870 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 GORGO|Ensembl=ENSGGOG00000026978.2|UniProtKB=G3SFD7 G3SFD7 KLF17 PTHR23235:SF159 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 17 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014520.3|UniProtKB=G3RF13 G3RF13 BNIP3 PTHR15186:SF4 RE48077P BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;programmed cell death#GO:0012501;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;apoptotic mitochondrial changes#GO:0008637;macroautophagy#GO:0016236;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;reticulophagy#GO:0061709 organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane#GO:0016020;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;outer membrane#GO:0019867;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 GORGO|Gene=NDUFAF1|UniProtKB=Q0MQ83 Q0MQ83 NDUFAF1 PTHR13194:SF23 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000014466.3|UniProtKB=G3REV6 G3REV6 PTHR15617:SF1 TRANSCRIPTION FACTOR GIBBIN TRANSCRIPTION FACTOR GIBBIN GORGO|Ensembl=ENSGGOG00000042064.1|UniProtKB=A0A2I2ZFU7 A0A2I2ZFU7 LOC101154476 PTHR10836:SF120 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (PHOSPHORYLATING) oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891 ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000009376.3|UniProtKB=G3R1S9 G3R1S9 RNF151 PTHR15315:SF64 RING FINGER PROTEIN 41, 151 RING FINGER PROTEIN 151 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 GORGO|Ensembl=ENSGGOG00000015448.3|UniProtKB=G3RHF0 G3RHF0 FAM3D PTHR14592:SF9 UNCHARACTERIZED FAM3 PROTEIN FAM3D cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000025211.2|UniProtKB=G3RU62 G3RU62 CNEP1R1 PTHR20996:SF2 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000011647.3|UniProtKB=G3R7P2 G3R7P2 FASN PTHR43775:SF7 FATTY ACID SYNTHASE FATTY ACID SYNTHASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000006838.3|UniProtKB=G3QVC5 G3QVC5 ZNF251 PTHR24377:SF1025 IP01015P-RELATED ZINC FINGER PROTEIN 251 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000027710.2|UniProtKB=G3S021 G3S021 LAPTM4A PTHR12479:SF5 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4A regulation of membrane permeability#GO:0090559;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000026706.2|UniProtKB=A0A2I2Y260 A0A2I2Y260 SNRPD1 PTHR23338:SF18 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000015352.3|UniProtKB=G3RH70 G3RH70 CPLANE1 PTHR14492:SF4 JBTS17 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 1 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 cilium#GO:0005929;ciliary transition zone#GO:0035869;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000006711.3|UniProtKB=G3QV07 G3QV07 RSPO4 PTHR46987:SF6 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-4 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical Wnt signaling pathway#GO:0060828 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000016535.3|UniProtKB=G3RK73 G3RK73 PTPN18 PTHR45983:SF4 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 18 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000025300.2|UniProtKB=A0A2I2YYZ8 A0A2I2YYZ8 PTHR11523:SF47 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3 ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;export from cell#GO:0140352;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082 ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000016488.3|UniProtKB=A0A2I2YWS1 A0A2I2YWS1 LUC7L PTHR12375:SF31 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN LUC7-LIKE 1-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525 GORGO|Ensembl=ENSGGOG00000004263.3|UniProtKB=G3QNR2 G3QNR2 SPDYC PTHR31545:SF2 SEEDY PROTEIN A/C FAMILY MEMBER SPEEDY PROTEIN C protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 GORGO|Ensembl=ENSGGOG00000014912.3|UniProtKB=G3RG15 G3RG15 SMPDL3B PTHR10340:SF25 SPHINGOMYELIN PHOSPHODIESTERASE ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3B phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000004296.3|UniProtKB=G3QNU1 G3QNU1 PTHR17314:SF0 REGULATED ENDOCRINE SPECIFIC PROTEIN 18 REGULATED ENDOCRINE-SPECIFIC PROTEIN 18 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000010793.3|UniProtKB=G3R5E8 G3R5E8 NUAK1 PTHR24343:SF350 SERINE/THREONINE KINASE NUAK FAMILY SNF1-LIKE KINASE 1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000026312.2|UniProtKB=G3S8A4 G3S8A4 PTHR45027:SF5 PUTATIVE GLUTATHIONE HYDROLASE LIGHT CHAIN GLUTATHIONE HYDROLASE LIGHT CHAIN 2-RELATED hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000039317.1|UniProtKB=A0A2I2ZDT5 A0A2I2ZDT5 PTHR10390:SF13 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000012628.3|UniProtKB=G3SII6 G3SII6 CDT1 PTHR28637:SF1 DNA REPLICATION FACTOR CDT1 DNA REPLICATION FACTOR CDT1 protein binding#GO:0005515;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;enzyme binding#GO:0019899 cell communication#GO:0007154;regulation of DNA replication#GO:0006275;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell cycle checkpoint signaling#GO:0000075;regulation of DNA-templated DNA replication initiation#GO:0030174;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;DNA integrity checkpoint signaling#GO:0031570;cellular process#GO:0009987;signal transduction#GO:0007165 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000009412.3|UniProtKB=G3R1W5 G3R1W5 PDILT PTHR18929:SF58 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE-LIKE PROTEIN OF THE TESTIS catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853 cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000001033.3|UniProtKB=G3RXQ2 G3RXQ2 AMOTL1 PTHR14826:SF12 ANGIOMOTIN ANGIOMOTIN-LIKE PROTEIN 1 system development#GO:0048731;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;cell motility#GO:0048870;establishment of cell polarity#GO:0030010;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;regulation of cell migration#GO:0030334;developmental process#GO:0032502;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;cell migration#GO:0016477;angiogenesis#GO:0001525;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;hippo signaling#GO:0035329;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cytoplasm#GO:0005737;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000037637.1|UniProtKB=A0A2I2YV72 A0A2I2YV72 PTHR23267:SF376 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014471.3|UniProtKB=G3S185 G3S185 PDE7B PTHR11347:SF72 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 7B hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000026719.2|UniProtKB=G3S5J9 G3S5J9 FAM171B PTHR31626:SF2 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171B GORGO|Ensembl=ENSGGOG00000004460.4|UniProtKB=G3QP98 G3QP98 DOCK5 PTHR45653:SF3 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 5 enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;syncytium formation by cell-cell fusion#GO:0000768;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;myoblast fusion#GO:0007520;muscle structure development#GO:0061061;cell migration#GO:0016477;cell motility#GO:0048870;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000015913.3|UniProtKB=G3RIL7 G3RIL7 SEMA3G PTHR11036:SF20 SEMAPHORIN SEMAPHORIN-3G signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;axon guidance#GO:0007411;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000026648.2|UniProtKB=G3S1A3 G3S1A3 STMN1 PTHR10104:SF5 STATHMIN STATHMIN protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular component disassembly#GO:0022411;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell development#GO:0048468;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule depolymerization#GO:0007019;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of microtubule-based process#GO:0032886;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;supramolecular fiber organization#GO:0097435;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;protein-containing complex disassembly#GO:0032984;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule polymerization or depolymerization#GO:0031109;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;protein depolymerization#GO:0051261 cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 Cytoskeletal regulation by Rho GTPase#P00016>Op18/stathmin#P00513 GORGO|Ensembl=ENSGGOG00000024903.2|UniProtKB=A0A2I2ZPK9 A0A2I2ZPK9 PTHR45787:SF3 LD11652P RHOMBOTIN-2 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;hemopoiesis#GO:0030097;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;embryonic organ development#GO:0048568;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000000555.3|UniProtKB=A0A2I2ZAT7 A0A2I2ZAT7 LAMP2 PTHR11506:SF6 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 2 lysosomal transport#GO:0007041;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular localization#GO:0051641;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;protein localization to lysosome#GO:0061462;cellular component organization#GO:0016043;establishment of protein localization to vacuole#GO:0072666;response to stimulus#GO:0050896;protein targeting#GO:0006605;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;response to stress#GO:0006950;protein targeting to vacuole#GO:0006623;autophagy#GO:0006914;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;protein localization to vacuole#GO:0072665;localization#GO:0051179;protein metabolic process#GO:0019538;response to starvation#GO:0042594;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;protein-containing complex disassembly#GO:0032984;cellular response to starvation#GO:0009267;autophagosome maturation#GO:0097352;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;cellular response to nutrient levels#GO:0031669;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;response to nutrient levels#GO:0031667;macromolecule localization#GO:0033036;macroautophagy#GO:0016236 vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;autophagosome membrane#GO:0000421;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000010510.3|UniProtKB=G3R4Q4 G3R4Q4 OSBPL3 PTHR10972:SF15 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 3 alcohol binding#GO:0043178;lipid binding#GO:0008289;steroid binding#GO:0005496;cholesterol binding#GO:0015485;binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934 cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;endomembrane system#GO:0012505;plasma membrane#GO:0005886;nuclear envelope#GO:0005635;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;organelle envelope#GO:0031967;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000010975.3|UniProtKB=G3R5X1 G3R5X1 PTHR14324:SF3 CONDENSIN-2 COMPLEX SUBUNIT H2 CONDENSIN-2 COMPLEX SUBUNIT H2 binding#GO:0005488;chromatin binding#GO:0003682 organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome separation#GO:0051304;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cell cycle#GO:0007049;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic cell cycle#GO:0000278;mitotic sister chromatid separation#GO:0051306;reproductive process#GO:0022414;nuclear division#GO:0000280;sexual reproduction#GO:0019953;organelle fission#GO:0048285;chromosome condensation#GO:0030261 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;condensin complex#GO:0000796 GORGO|Ensembl=ENSGGOG00000008245.3|UniProtKB=G3SGC4 G3SGC4 SNRNP70 PTHR13952:SF5 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000015726.3|UniProtKB=G3RI54 G3RI54 CHAF1B PTHR15271:SF4 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000013287.3|UniProtKB=G3RBU5 G3RBU5 MFNG PTHR10811:SF6 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593 transferase#PC00220;glycosyltransferase#PC00111 Notch signaling pathway#P00045>Fringe#P01107 GORGO|Ensembl=ENSGGOG00000006761.3|UniProtKB=A0A2I2YDI6 A0A2I2YDI6 GK PTHR10196:SF56 SUGAR KINASE GLYCEROL KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;alcohol metabolic process#GO:0006066;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829 carbohydrate kinase#PC00065;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000000533.3|UniProtKB=G3QE40 G3QE40 MRTO4 PTHR45841:SF2 MRNA TURNOVER PROTEIN 4 MRTO4 MRNA TURNOVER PROTEIN 4 HOMOLOG RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;rRNA processing#GO:0006364;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000024274.2|UniProtKB=G3SD81 G3SD81 RPL15 PTHR11847:SF4 RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN EL15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013989.3|UniProtKB=G3RDN2 G3RDN2 LOC101138012 PTHR26450:SF73 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51S1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026795.2|UniProtKB=G3RLT2 G3RLT2 KCNE4 PTHR15282:SF9 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 4 molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;channel activity#GO:0015267;channel regulator activity#GO:0016247;potassium ion transmembrane transporter activity#GO:0015079;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;transmembrane transporter binding#GO:0044325;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;potassium channel regulator activity#GO:0015459;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488 biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;actin filament-based movement#GO:0030048;heart contraction#GO:0060047;system process#GO:0003008;cardiac muscle cell contraction#GO:0086003;establishment of localization#GO:0051234;muscle contraction#GO:0006936;transport#GO:0006810;regulation of system process#GO:0044057;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;regulation of heart contraction#GO:0008016;actin-mediated cell contraction#GO:0070252;localization#GO:0051179;monoatomic cation transport#GO:0006812;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;circulatory system process#GO:0003013;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;cardiac muscle cell action potential involved in contraction#GO:0086002;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;export from cell#GO:0140352;regulation of biological process#GO:0050789;action potential#GO:0001508;muscle system process#GO:0003012;heart process#GO:0003015;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000016940.3|UniProtKB=G3RX04 G3RX04 SYT15 PTHR10024:SF234 SYNAPTOTAGMIN SYNAPTOTAGMIN-15-RELATED SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;protein binding#GO:0005515 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular process#GO:0009987;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794;transport#GO:0006810;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;localization#GO:0051179;regulation of secretion#GO:0051046;establishment of localization#GO:0051234 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 GORGO|Ensembl=ENSGGOG00000004983.3|UniProtKB=G3QQL4 G3QQL4 FGF9 PTHR11486:SF28 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 9 growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000005937.3|UniProtKB=G3QT05 G3QT05 MNDA PTHR12200:SF27 INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER MYELOID CELL NUCLEAR DIFFERENTIATION ANTIGEN double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of response to biotic stimulus#GO:0002831;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;immune system process#GO:0002376;response to peptide#GO:1901652;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;positive regulation of response to external stimulus#GO:0032103 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000024187.2|UniProtKB=G3S493 G3S493 LOC101128125 PTHR12728:SF0 BRIX DOMAIN CONTAINING PROTEIN RIBOSOME PRODUCTION FACTOR 2 HOMOLOG binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000025545.2|UniProtKB=G3RW53 G3RW53 PTHR23143:SF22 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 7 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000008410.3|UniProtKB=G3QZC9 G3QZC9 TRPM2 PTHR13800:SF2 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 2 gated channel activity#GO:0022836;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261 monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;calcium ion transmembrane import into cytosol#GO:0097553;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;calcium ion transmembrane transport#GO:0070588 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012856.3|UniProtKB=G3RAR1 G3RAR1 PYGO2 PTHR23194:SF7 PYGOPUS PYGOPUS HOMOLOG 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;Wnt signaling pathway#GO:0016055;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell surface receptor signaling pathway#GO:0007166 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 Wnt signaling pathway#P00057>Pygo#P01464 GORGO|Ensembl=ENSGGOG00000023984.2|UniProtKB=G3R7H3 G3R7H3 LOC101150071 PTHR11937:SF176 ACTIN ACTIN, ALPHA CARDIAC MUSCLE 1 protein binding#GO:0005515;structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200;myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 heart contraction#GO:0060047;actin filament organization#GO:0007015;system process#GO:0003008;cellular component organization or biogenesis#GO:0071840;actin filament-based movement#GO:0030048;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;actin filament-based process#GO:0030029;circulatory system process#GO:0003013;supramolecular fiber organization#GO:0097435;heart process#GO:0003015;cellular component organization#GO:0016043;actin-mediated cell contraction#GO:0070252;actin cytoskeleton organization#GO:0030036 contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;actin filament#GO:0005884;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;sarcomere#GO:0030017;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470 GORGO|Ensembl=ENSGGOG00000013405.3|UniProtKB=G3RMF6 G3RMF6 TLK1 PTHR22974:SF22 MIXED LINEAGE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TOUSLED-LIKE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;chromosome segregation#GO:0007059 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000013961.3|UniProtKB=G3RDL1 G3RDL1 SIRT7 PTHR11085:SF1 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-7 deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 response to stimulus#GO:0050896;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;response to stress#GO:0006950;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000024523.2|UniProtKB=G3SAG0 G3SAG0 LOC109023149 PTHR11961:SF15 CYTOCHROME C CYTOCHROME C, SOMATIC aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ATP synthesis#P02721>Cyt C#P02798;Apoptosis signaling pathway#P00006>Cytochrome C#P00322 GORGO|Ensembl=ENSGGOG00000025603.2|UniProtKB=G3SI55 G3SI55 RBM11 PTHR13798:SF5 RNA BINDING MOTIF RBM PROTEIN -RELATED SPLICING REGULATOR RBM11 RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014281.3|UniProtKB=G3REE5 G3REE5 TADA3 PTHR13556:SF2 TRANSCRIPTIONAL ADAPTER 3-RELATED TRANSCRIPTIONAL ADAPTER 3 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000026319.2|UniProtKB=G3RMK2 G3RMK2 LOC101150350 PTHR11363:SF10 60S RIBOSOMAL PROTEIN L3-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL3 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000023233.2|UniProtKB=G3S735 G3S735 LOC101131889 PTHR26453:SF286 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T33-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013377.3|UniProtKB=A0A2I2YY26 A0A2I2YY26 KCNQ1 PTHR11537:SF274 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1 transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 muscle contraction#GO:0006936;transport#GO:0006810;system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle cell contraction#GO:0086003;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;actin filament-based movement#GO:0030048;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cardiac muscle cell action potential involved in contraction#GO:0086002;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;action potential#GO:0001508;muscle system process#GO:0003012;heart process#GO:0003015;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;actin-mediated cell contraction#GO:0070252 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000006224.3|UniProtKB=G3RVT8 G3RVT8 PTHR19944:SF98 MHC CLASS II-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277;protein-containing complex binding#GO:0044877 immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522 late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000015510.3|UniProtKB=G3SA03 G3SA03 GEMIN4 PTHR15571:SF2 GEM-ASSOCIATED PROTEIN 4 GEM-ASSOCIATED PROTEIN 4 spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 membrane-bounded organelle#GO:0043227;SMN complex#GO:0032797;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000034917.2|UniProtKB=G3SKQ8 G3SKQ8 EHBP1 PTHR23167:SF43 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED EH DOMAIN-BINDING PROTEIN 1 cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004318.2|UniProtKB=G3QNV6 G3QNV6 LOC101144471 PTHR24377:SF703 IP01015P-RELATED ZINC FINGER PROTEIN 610 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008083.3|UniProtKB=A0A2I2YTG6 A0A2I2YTG6 ATR PTHR11139:SF133 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE ATR protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular response to stress#GO:0033554;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;telomere organization#GO:0032200;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;DNA integrity checkpoint signaling#GO:0031570 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>ATM/ATR#P01481;p53 pathway feedback loops 2#P04398>ATM#P04669 GORGO|Ensembl=ENSGGOG00000012687.3|UniProtKB=G3RAB3 G3RAB3 LAD1 PTHR12392:SF0 LADININ 1 LADININ-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000024821.2|UniProtKB=G3S742 G3S742 PPP4R3C PTHR23318:SF19 ATP SYNTHASE GAMMA-RELATED PROTEIN PPP4R3C enzyme activator activity#GO:0008047;phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 DNA damage response#GO:0006974;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;cellular response to stress#GO:0033554;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of DNA metabolic process#GO:0051052 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000036462.1|UniProtKB=G3S5S9 G3S5S9 PTHR23095:SF40 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 6A transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000002010.4|UniProtKB=A0A2I2YBZ7 A0A2I2YBZ7 HSD17B4 PTHR13078:SF56 PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002368.3|UniProtKB=G3S1C1 G3S1C1 LOC101150478 PTHR24123:SF124 ANKYRIN REPEAT-CONTAINING TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY A MEMBER 1 gated channel activity#GO:0022836;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;detection of chemical stimulus#GO:0009593;calcium ion transmembrane transport#GO:0070588;sensory perception of pain#GO:0019233;metal ion transport#GO:0030001;response to stimulus#GO:0050896;transport#GO:0006810;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;cellular process#GO:0009987;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;response to chemical#GO:0042221;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006541.3|UniProtKB=G3QUJ6 G3QUJ6 ACADL PTHR48083:SF20 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;carnitine metabolic process#GO:0009437;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000002696.3|UniProtKB=G3QJQ7 G3QJQ7 DYNC1I2 PTHR12442:SF37 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 2 binding#GO:0005488;protein binding#GO:0005515 microtubule-based transport#GO:0099111;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;microtubule-based movement#GO:0007018;cytoskeleton-dependent intracellular transport#GO:0030705 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000002800.3|UniProtKB=A0A2I2ZSL7 A0A2I2ZSL7 HPSE PTHR46145:SF3 HEPARANASE HEPARANASE vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;multicellular organismal process#GO:0032501;cellular process#GO:0009987;response to stress#GO:0006950;response to wounding#GO:0009611;system development#GO:0048731;wound healing#GO:0042060;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;blood vessel morphogenesis#GO:0048514 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000037269.1|UniProtKB=A0A2I2ZPZ5 A0A2I2ZPZ5 PTHR12642:SF4 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000002502.3|UniProtKB=A0A2I2YP06 A0A2I2YP06 NME7 PTHR43109:SF2 NUCLEOSIDE DIPHOSPHATE KINASE 7 NUCLEOSIDE DIPHOSPHATE KINASE 7 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;intracellular organelle#GO:0043229;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881 transferase#PC00220;kinase#PC00137 De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907 GORGO|Ensembl=ENSGGOG00000009522.3|UniProtKB=G3R258 G3R258 FABP1 PTHR11955:SF96 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, LIVER organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;lipid binding#GO:0008289;fatty acid binding#GO:0005504 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000000311.3|UniProtKB=G3QDI7 G3QDI7 ASB10 PTHR24161:SF123 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT AND SOCS BOX PROTEIN 10 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000043845.1|UniProtKB=A0A2I2ZUR5 A0A2I2ZUR5 CCL22 PTHR12015:SF102 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 22 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488 cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cell migration#GO:0016477;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;myeloid leukocyte migration#GO:0097529;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;response to cytokine#GO:0034097;taxis#GO:0042330;response to chemical#GO:0042221;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000007149.3|UniProtKB=A0A2I2YKX2 A0A2I2YKX2 YIPF6 PTHR21236:SF1 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF6 Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000025296.2|UniProtKB=G3S4I1 G3S4I1 CCDC59 PTHR15657:SF1 THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008482.3|UniProtKB=A0A2I2ZP40 A0A2I2ZP40 ALCAM PTHR11973:SF2 CELL SURFACE GLYCOPROTEIN MUC18-RELATED CD166 ANTIGEN multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000015650.3|UniProtKB=G3RHZ8 G3RHZ8 IREB2 PTHR11670:SF31 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER IRON-RESPONSIVE ELEMENT-BINDING PROTEIN 2 hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824;iron-sulfur cluster binding#GO:0051536;RNA binding#GO:0003723;lyase activity#GO:0016829;binding#GO:0005488;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;mRNA binding#GO:0003729 inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 GORGO|Ensembl=ENSGGOG00000013466.3|UniProtKB=G3RCB2 G3RCB2 ATP6AP1 PTHR12471:SF2 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of pH#GO:0006885;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;regulation of intracellular pH#GO:0051453;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 proton-transporting V-type ATPase complex#GO:0033176;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;ATPase complex#GO:1904949;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000010044.3|UniProtKB=G3S0U0 G3S0U0 CEACAM5 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000009610.3|UniProtKB=G3R2D6 G3R2D6 MGAT1 PTHR10468:SF12 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1/ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000037276.1|UniProtKB=G3RRX6 G3RRX6 PTHR23266:SF369 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-72 antigen binding#GO:0003823;binding#GO:0005488 immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000042477.1|UniProtKB=A0A2I2YE49 A0A2I2YE49 ST8SIA3 PTHR11987:SF36 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-N-ACETYLNEURAMINATE ALPHA-2,8-SIALYLTRANSFERASE ST8SIA3 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;oligosaccharide metabolic process#GO:0009311;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006906.3|UniProtKB=G3S0X8 G3S0X8 SOX8 PTHR45803:SF2 SOX100B TRANSCRIPTION FACTOR SOX-8 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;peripheral nervous system development#GO:0007422;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;morphogenesis of an epithelium#GO:0002009;animal organ development#GO:0048513;multicellular organism development#GO:0007275;mesenchymal cell differentiation#GO:0048762;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neural crest cell differentiation#GO:0014033;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;tissue morphogenesis#GO:0048729;stem cell development#GO:0048864;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;neural crest cell development#GO:0014032;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;stem cell differentiation#GO:0048863;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;mesenchyme development#GO:0060485;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000002683.3|UniProtKB=G3QJP3 G3QJP3 TFEB PTHR45776:SF5 MIP04163P TRANSCRIPTION FACTOR EB sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;vacuole organization#GO:0007033;regulation of RNA metabolic process#GO:0051252;positive regulation of autophagy#GO:0010508;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;lysosome organization#GO:0007040;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;lytic vacuole organization#GO:0080171;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000008569.3|UniProtKB=G3QZR2 G3QZR2 DDB2 PTHR15169:SF0 DAMAGE-SPECIFIC DNA BINDING PROTEIN 2 DNA DAMAGE-BINDING PROTEIN 2 damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to abiotic stimulus#GO:0009628;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;response to radiation#GO:0009314;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to UV#GO:0009411;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 damaged DNA-binding protein#PC00086 p53 pathway#P00059>p48#G04705 GORGO|Ensembl=ENSGGOG00000008967.3|UniProtKB=G3SHZ2 G3SHZ2 RASA3 PTHR10194:SF53 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 3 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000005750.3|UniProtKB=G3QSJ0 G3QSJ0 SLC49A3 PTHR10924:SF6 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER A3 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000012146.3|UniProtKB=G3R8X6 G3R8X6 PTHR17615:SF6 PROTEIN FAM189A PROTEIN ENTREP2 GORGO|Ensembl=ENSGGOG00000007567.2|UniProtKB=G3QX71 G3QX71 PTHR31564:SF0 ANAPHASE-PROMOTING COMPLEX SUBUNIT 16 ANAPHASE-PROMOTING COMPLEX SUBUNIT 16 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152 GORGO|Ensembl=ENSGGOG00000013177.3|UniProtKB=G3RBJ9 G3RBJ9 LOC101146509 PTHR11476:SF6 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;translation#GO:0006412;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000021945.2|UniProtKB=G3RZY3 G3RZY3 NCALD PTHR23055:SF87 CALCIUM BINDING PROTEINS NEUROCALCIN-DELTA cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;actin binding#GO:0003779;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 cell communication#GO:0007154;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000000784.3|UniProtKB=G3QES4 G3QES4 PTHR23138:SF160 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intracellular transport#GO:0046907;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011250.3|UniProtKB=A0A2I2Y1U9 A0A2I2Y1U9 TSPYL5 PTHR11875:SF30 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 5 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000012481.3|UniProtKB=A0A2I2YXA5 A0A2I2YXA5 PTHR23039:SF2 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 2 GORGO|Ensembl=ENSGGOG00000012004.3|UniProtKB=G3R8K1 G3R8K1 INO80E PTHR21812:SF1 INO80 COMPLEX SUBUNIT E INO80 COMPLEX SUBUNIT E regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;positive regulation of RNA metabolic process#GO:0051254;cellular component organization#GO:0016043;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;regulation of DNA replication#GO:0006275;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;Ino80 complex#GO:0031011;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000001608.3|UniProtKB=G3SK58 G3SK58 THUMPD2 PTHR14911:SF1 THUMP DOMAIN-CONTAINING U6 SNRNA (GUANINE-N(2))-METHYLTRANSFERASE THUMPD2 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000010679.3|UniProtKB=G3R548 G3R548 LOC101140563 PTHR16675:SF146 MHC CLASS I-RELATED T-CELL SURFACE GLYCOPROTEIN CD1E, MEMBRANE-ASSOCIATED antigen binding#GO:0003823;binding#GO:0005488;lipid binding#GO:0008289 regulation of leukocyte mediated cytotoxicity#GO:0001910;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000008792.3|UniProtKB=G3R0B3 G3R0B3 SLC1A5 PTHR11958:SF19 SODIUM/DICARBOXYLATE SYMPORTER-RELATED NEUTRAL AMINO ACID TRANSPORTER B(0) symporter activity#GO:0015293;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;C4-dicarboxylate transmembrane transporter activity#GO:0015556;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172 import into cell#GO:0098657;establishment of localization#GO:0051234;amino acid transport#GO:0006865;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;nitrogen compound transport#GO:0071705;aspartate transmembrane transport#GO:0015810;L-amino acid transport#GO:0015807;cellular process#GO:0009987;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179;L-glutamate import#GO:0051938;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000000285.3|UniProtKB=G3QDG5 G3QDG5 URB1 PTHR13500:SF0 NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1 NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1 nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000006345.3|UniProtKB=G3QU16 G3QU16 SERPINA12 PTHR11461:SF157 SERINE PROTEASE INHIBITOR, SERPIN SERPIN A12 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000007938.3|UniProtKB=G3QY48 G3QY48 CLTC PTHR10292:SF7 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN 1 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;endocytosis#GO:0006897;mitotic cell cycle#GO:0000278;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cell cycle#GO:0007049;localization#GO:0051179 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;membraneless organelle#GO:0043228;clathrin-coated endocytic vesicle#GO:0045334;spindle#GO:0005819;cytoskeleton#GO:0005856;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738 GORGO|Ensembl=ENSGGOG00000000206.3|UniProtKB=G3QD96 G3QD96 TEP1 PTHR44791:SF1 TELOMERASE PROTEIN COMPONENT 1 TEP1 TELOMERASE PROTEIN COMPONENT 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA-directed DNA polymerase activity#GO:0003964;RNA binding#GO:0003723;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA polymerase activity#GO:0034061;telomerase activity#GO:0003720;catalytic activity, acting on DNA#GO:0140097 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;mitotic recombination#GO:0006312 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000011724.4|UniProtKB=G3R7X3 G3R7X3 PTHR13743:SF62 BEIGE/BEACH-RELATED NEUROBEACHIN protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005203.3|UniProtKB=A0A2I2YRB3 A0A2I2YRB3 NDRG2 PTHR11034:SF59 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG2 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000009589.3|UniProtKB=G3R2C0 G3R2C0 PTHR46487:SF1 DNA REPAIR PROTEIN XRCC3 DNA REPAIR PROTEIN XRCC3 four-way junction DNA binding#GO:0000400;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;telomere organization#GO:0032200;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;replication fork#GO:0005657;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000037535.1|UniProtKB=A0A2I2Z1Y0 A0A2I2Z1Y0 PTHR23236:SF44 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4B nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000014654.3|UniProtKB=A0A2I2YZD7 A0A2I2YZD7 LOC101154200 PTHR24379:SF98 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 44 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016022.3|UniProtKB=G3RIW3 G3RIW3 DBH PTHR10157:SF29 DOPAMINE BETA HYDROXYLASE RELATED DOPAMINE BETA-HYDROXYLASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;phenol-containing compound biosynthetic process#GO:0046189;amine metabolic process#GO:0009308;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;response to stimulus#GO:0050896;response to chemical#GO:0042221;catabolic process#GO:0009056;response to alcohol#GO:0097305;multicellular organismal process#GO:0032501;amine catabolic process#GO:0009310;response to oxygen-containing compound#GO:1901700;metabolic process#GO:0008152;catecholamine metabolic process#GO:0006584 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydroxylase#PC00122 Dopamine receptor mediated signaling pathway#P05912>DBH#P05955;Adrenaline and noradrenaline biosynthesis#P00001>DBH#P00063 GORGO|Ensembl=ENSGGOG00000013363.3|UniProtKB=G3RC14 G3RC14 OR51V1 PTHR26450:SF67 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51V1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037674.1|UniProtKB=A0A2I2ZC10 A0A2I2ZC10 PTHR23316:SF6 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-4 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025173.2|UniProtKB=G3SIK1 G3SIK1 KMT2C PTHR45888:SF1 HL01030P-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE 2C methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;transcription regulator activity#GO:0140110;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;transcription coactivator activity#GO:0003713;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone H3 methyltransferase activity#GO:0140938;histone H3K4 methyltransferase activity#GO:0042800;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000013207.3|UniProtKB=G3RBM3 G3RBM3 ZNF674 PTHR24381:SF125 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 674 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000027926.2|UniProtKB=G3SJI0 G3SJI0 ZCCHC8 PTHR13316:SF0 ZINC FINGER, CCHC DOMAIN CONTAINING 8 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000034899.2|UniProtKB=A0A2I2YGK4 A0A2I2YGK4 PCMTD2 PTHR11579:SF2 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 2 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;O-methyltransferase activity#GO:0008171;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009301.3|UniProtKB=G3S1H4 G3S1H4 TXNL1 PTHR46115:SF1 THIOREDOXIN-LIKE PROTEIN 1 THIOREDOXIN-LIKE PROTEIN 1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122 GORGO|Ensembl=ENSGGOG00000010406.3|UniProtKB=G3R4F2 G3R4F2 LONRF1 PTHR23327:SF4 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000117.3|UniProtKB=G3QD13 G3QD13 CABLES2 PTHR22896:SF3 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CDK5 AND ABL1 ENZYME SUBSTRATE 2 GORGO|Ensembl=ENSGGOG00000012890.3|UniProtKB=G3RW18 G3RW18 RUNX2 PTHR11950:SF7 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;ossification#GO:0001503;regulation of developmental process#GO:0050793;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;cartilage development#GO:0051216;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;chondrocyte differentiation#GO:0002062;multicellular organismal process#GO:0032501;tissue development#GO:0009888;hemopoiesis#GO:0030097;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;connective tissue development#GO:0061448;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;skeletal system development#GO:0001501;cellular process#GO:0009987;nervous system development#GO:0007399;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;animal organ development#GO:0048513 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;Runt transcription factor#PC00254 GORGO|Ensembl=ENSGGOG00000008776.3|UniProtKB=A0A2I2YSD0 A0A2I2YSD0 CCDC42 PTHR21683:SF8 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 42 developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;cellular process#GO:0009987;male gamete generation#GO:0048232;spermatid development#GO:0007286;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000000583.3|UniProtKB=A0A2I2YPE7 A0A2I2YPE7 SSH2 PTHR45864:SF3 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 2 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488;actin binding#GO:0003779 negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 GORGO|Ensembl=ENSGGOG00000016884.3|UniProtKB=G3RL38 G3RL38 SPHK1 PTHR12358:SF47 SPHINGOSINE KINASE SPHINGOSINE KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;primary metabolic process#GO:0044238;cellular response to growth factor stimulus#GO:0071363;sphingoid biosynthetic process#GO:0046520;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of apoptotic process#GO:0043066;lipid biosynthetic process#GO:0008610;negative regulation of programmed cell death#GO:0043069;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;regulation of apoptotic process#GO:0042981;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 VEGF signaling pathway#P00056>SPK#P01404;Angiogenesis#P00005>SPK#P00229 GORGO|Ensembl=ENSGGOG00000000203.3|UniProtKB=G3QD90 G3QD90 TRMU PTHR11933:SF9 TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1 catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on RNA#GO:0140098;sulfurtransferase activity#GO:0016783;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;mitochondrial RNA modification#GO:1900864;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA wobble position uridine thiolation#GO:0002143 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000042383.1|UniProtKB=A0A2I2Y3V1 A0A2I2Y3V1 MRPL22 PTHR13501:SF10 CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005285.3|UniProtKB=G3QRD0 G3QRD0 TXNL4A PTHR12052:SF5 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4A macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000001429.3|UniProtKB=G3RNG2 G3RNG2 NEFL PTHR45652:SF8 GLIAL FIBRILLARY ACIDIC PROTEIN NEUROFILAMENT LIGHT POLYPEPTIDE structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918;structural constituent of cytoskeleton#GO:0005200 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;intermediate filament bundle assembly#GO:0045110;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;neuron projection#GO:0043005;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;axon#GO:0030424;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000015686.3|UniProtKB=G3RI22 G3RI22 CEP112 PTHR18871:SF2 CENTROSOMAL PROTEIN OF 112 KDA CENTROSOMAL PROTEIN OF 112 KDA GORGO|Ensembl=ENSGGOG00000001114.3|UniProtKB=G3QFM0 G3QFM0 MED28 PTHR13512:SF2 MEDIATOR COMPLEX SUBUNIT 28 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 28 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000028243.2|UniProtKB=G3RUH5 G3RUH5 SUV39H2 PTHR46223:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2 protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000013325.3|UniProtKB=A0A2I2YMK8 A0A2I2YMK8 LOC101123742 PTHR24291:SF132 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 FAMILY 4 SUBFAMILY F MEMBER 12 carboxylic acid metabolic process#GO:0019752;vitamin K metabolic process#GO:0042373;ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;arachidonate metabolic process#GO:0019369;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;icosanoid metabolic process#GO:0006690;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000015238.3|UniProtKB=G3RGV6 G3RGV6 PHF10 PTHR10615:SF174 HISTONE ACETYLTRANSFERASE PHD FINGER PROTEIN 10 protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;acetyltransferase activity#GO:0016407;binding#GO:0005488;transcription regulator activity#GO:0140110;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;histone acetyltransferase activity#GO:0004402;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000014268.3|UniProtKB=G3RED6 G3RED6 CAMK1 PTHR24347:SF197 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;regulation of synapse organization#GO:0050807;regulation of synapse structure or activity#GO:0050803;cell communication#GO:0007154;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879 postsynapse#GO:0098794;cytoplasm#GO:0005737;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic density#GO:0014069;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000012514.3|UniProtKB=G3R9W7 G3R9W7 ZC3H18 PTHR46582:SF1 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 GORGO|Ensembl=ENSGGOG00000007602.4|UniProtKB=G3QX97 G3QX97 COMMD1 PTHR21199:SF1 COMM DOMAIN-CONTAINING PROTEIN 1 COMM DOMAIN-CONTAINING PROTEIN 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;localization#GO:0051179;regulation of protein catabolic process#GO:0042176;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein ubiquitination#GO:0031396;transport#GO:0006810;establishment of localization#GO:0051234;regulation of protein modification process#GO:0031399;regulation of catabolic process#GO:0009894 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000007425.3|UniProtKB=G3QWV1 G3QWV1 EIF2B5 PTHR45887:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON TRANSLATION INITIATION FACTOR EIF2B SUBUNIT EPSILON translation factor activity#GO:0180051;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;translation initiation factor binding#GO:0031369;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;protein binding#GO:0005515;enzyme regulator activity#GO:0030234 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000039385.1|UniProtKB=A0A2I2YSS8 A0A2I2YSS8 PTHR20854:SF41 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000001457.3|UniProtKB=G3QGI1 G3QGI1 STX1A PTHR19957:SF84 SYNTAXIN SYNTAXIN-1A SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular protein localization#GO:0008104;exocytosis#GO:0006887;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;secretion by cell#GO:0032940;protein transport#GO:0015031;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;vesicle fusion#GO:0006906;export from cell#GO:0140352;cellular component organization#GO:0016043 cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091 GORGO|Ensembl=ENSGGOG00000004382.3|UniProtKB=G3QP12 G3QP12 LOC101136303 PTHR23236:SF105 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4B binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000025848.2|UniProtKB=G3SED8 G3SED8 PRR20G PTHR38819:SF1 PROLINE-RICH PROTEIN 20A-RELATED PROLINE-RICH PROTEIN 20A-RELATED GORGO|Ensembl=ENSGGOG00000024263.2|UniProtKB=G3RYE8 G3RYE8 RWDD3 PTHR15628:SF1 RWD DOMAIN-CONTAINING PROTEIN 3 RWD DOMAIN-CONTAINING PROTEIN 3 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;positive regulation of response to stimulus#GO:0048584;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056 GORGO|Ensembl=ENSGGOG00000003838.3|UniProtKB=G3QMM9 G3QMM9 INTS14 PTHR13532:SF3 FAMILY NOT NAMED INTEGRATOR COMPLEX SUBUNIT 14 GORGO|Ensembl=ENSGGOG00000002034.3|UniProtKB=G3QI12 G3QI12 SUCLG1 PTHR11117:SF2 SUCCINYL-COA LIGASE SUBUNIT ALPHA SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;cellular process#GO:0009987;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;ligase#PC00142 TCA cycle#P00051>Succinyl CoA Synthetase#P01274 GORGO|Ensembl=ENSGGOG00000043581.1|UniProtKB=A0A2I2Y460 A0A2I2Y460 CBX6 PTHR46389:SF4 POLYCOMB GROUP PROTEIN PC CHROMOBOX PROTEIN HOMOLOG 6 binding#GO:0005488;chromatin binding#GO:0003682 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;PcG protein complex#GO:0031519;nucleus#GO:0005634;chromatin#GO:0000785;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004438.3|UniProtKB=A0A2I2ZAR8 A0A2I2ZAR8 ZC3H11A PTHR15725:SF2 ZN-FINGER, C-X8-C-X5-C-X3-H TYPE-CONTAINING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 11A RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000005094.3|UniProtKB=G3QQW5 G3QQW5 PFDN2 PTHR13303:SF0 PREFOLDIN SUBUNIT 2 PREFOLDIN SUBUNIT 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058 protein-containing complex#GO:0032991 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000000298.3|UniProtKB=G3QDH5 G3QDH5 GRIP1 PTHR46227:SF3 GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 protein localization to synapse#GO:0035418;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;protein localization to cell periphery#GO:1990778;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;endosome to plasma membrane protein transport#GO:0099638;localization#GO:0051179;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;protein transport#GO:0015031;protein localization to cell junction#GO:1902414;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;endocytic recycling#GO:0032456;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659 GORGO|Ensembl=ENSGGOG00000024246.2|UniProtKB=G3RYM7 G3RYM7 GPR22 PTHR24241:SF1 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 22 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004606.3|UniProtKB=G3QPL9 G3QPL9 CXCL9 PTHR12015:SF210 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 9 chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009 cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cell motility#GO:0048870;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;response to other organism#GO:0051707;biological regulation#GO:0065007;cell migration#GO:0016477;leukocyte migration#GO:0050900;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;response to peptide#GO:1901652;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;response to lipid#GO:0033993;granulocyte migration#GO:0097530;cellular response to lipid#GO:0071396;neutrophil migration#GO:1990266;response to chemical#GO:0042221;taxis#GO:0042330;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166;neutrophil chemotaxis#GO:0030593;response to lipopolysaccharide#GO:0032496 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000004464.3|UniProtKB=G3QP92 G3QP92 RUSF1 PTHR12770:SF31 RUS1 FAMILY PROTEIN C16ORF58 RUS FAMILY MEMBER 1 GORGO|Ensembl=ENSGGOG00000003297.3|UniProtKB=G3QL90 G3QL90 BRS3 PTHR45695:SF6 LEUCOKININ RECEPTOR-RELATED BOMBESIN RECEPTOR SUBTYPE-3 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025791.2|UniProtKB=G3S5Y5 G3S5Y5 PTHR13802:SF66 MUCIN 4-RELATED MUCIN-4 system process#GO:0003008;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;digestion#GO:0007586;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000024338.2|UniProtKB=A0A2I2YXN7 A0A2I2YXN7 MITF PTHR45776:SF4 MIP04163P MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental pigmentation#GO:0048066;cellular process#GO:0009987;melanocyte differentiation#GO:0030318;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;pigmentation#GO:0043473;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004358.3|UniProtKB=G3QP03 G3QP03 WDFY4 PTHR46108:SF3 BLUE CHEESE WD REPEAT- AND FYVE DOMAIN-CONTAINING PROTEIN 4 antigen processing and presentation#GO:0019882;immune system process#GO:0002376 GORGO|Ensembl=ENSGGOG00000037689.1|UniProtKB=A0A2I2YM85 A0A2I2YM85 C1QTNF9 PTHR15427:SF21 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q AND TUMOR NECROSIS FACTOR-RELATED PROTEIN 9A molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;lipid oxidation#GO:0034440;lipid modification#GO:0030258;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037201.1|UniProtKB=A0A2I2ZUE2 A0A2I2ZUE2 LOC101138283 PTHR10288:SF260 KH DOMAIN CONTAINING RNA BINDING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015181.3|UniProtKB=G3RGQ6 G3RGQ6 CREB3L1 PTHR46004:SF1 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383 GORGO|Ensembl=ENSGGOG00000011353.3|UniProtKB=G3R6U7 G3R6U7 ABO PTHR10462:SF29 GLYCOSYLTRANSFERASE-RELATED HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 vesicle#GO:0031982;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000014815.3|UniProtKB=G3RFT0 G3RFT0 SMARCAL1 PTHR45766:SF6 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER SNF2 RELATED CHROMATIN REMODELING ANNEALING HELICASE 1 ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386 replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554 replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000042470.1|UniProtKB=A0A2I2YVF9 A0A2I2YVF9 PTHR13160:SF12 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane protein complex#GO:0098796;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000037020.1|UniProtKB=A0A2I2YDR6 A0A2I2YDR6 MUC7 PTHR41683:SF1 MUCIN-7 MUCIN-7 GORGO|Ensembl=ENSGGOG00000024641.2|UniProtKB=A0A2I2YLY5 A0A2I2YLY5 PTHR11431:SF37 FERRITIN FERRITIN HEAVY CHAIN iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000002766.3|UniProtKB=A0A2I2Z7L6 A0A2I2Z7L6 GALNTL6 PTHR11675:SF129 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE-LIKE 6 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000010683.3|UniProtKB=G3R553 G3R553 MRPS27 PTHR21393:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN MS27 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016494.3|UniProtKB=G3RK38 G3RK38 RPUSD4 PTHR21600:SF81 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD4, MITOCHONDRIAL catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000037025.1|UniProtKB=A0A2I2YUC3 A0A2I2YUC3 PTHR10544:SF12 60S RIBOSOMAL PROTEIN L28 LARGE RIBOSOMAL SUBUNIT PROTEIN EL28 cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009870.3|UniProtKB=G3R331 G3R331 MTBP PTHR14382:SF1 MDM2-BINDING PROTEIN MDM2-BINDING PROTEIN intracellular protein localization#GO:0008104;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;macromolecule localization#GO:0033036;protein localization to kinetochore#GO:0034501;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic cell cycle phase transition#GO:1901990;localization#GO:0051179;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779 GORGO|Ensembl=ENSGGOG00000026870.2|UniProtKB=A0A2I2YQ66 A0A2I2YQ66 PTHR26453:SF186 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027455.2|UniProtKB=A0A2I2Z934 A0A2I2Z934 RPS3A PTHR11830:SF28 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012126.3|UniProtKB=G3R8V8 G3R8V8 GSTK1 PTHR42943:SF2 GLUTATHIONE S-TRANSFERASE KAPPA GLUTATHIONE S-TRANSFERASE KAPPA 1 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000039052.1|UniProtKB=A0A2I2ZAV7 A0A2I2ZAV7 C1R PTHR24255:SF25 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1R SUBCOMPONENT catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 zymogen activation#GO:0031638;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000002136.3|UniProtKB=A0A2I2Y8T2 A0A2I2Y8T2 TMEM126B PTHR16296:SF3 UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007 COMPLEX I ASSEMBLY FACTOR TMEM126B, MITOCHONDRIAL protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000012401.3|UniProtKB=G3R9L7 G3R9L7 PTHR15874:SF1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;establishment of spindle localization#GO:0051293;mitotic sister chromatid segregation#GO:0000070;organelle localization#GO:0051640;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cell division#GO:0051301;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytokinesis#GO:0000910;nuclear division#GO:0000280;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;cellular localization#GO:0051641;spindle localization#GO:0051653;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;establishment of organelle localization#GO:0051656 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000022391.2|UniProtKB=A0A2I2ZV47 A0A2I2ZV47 PTHR13160:SF9 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000000912.3|UniProtKB=G3QF36 G3QF36 CCDC22 PTHR15668:SF5 JM1 PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 22 binding#GO:0005488;protein binding#GO:0005515 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;establishment of localization#GO:0051234;positive regulation of catabolic process#GO:0009896;vesicle-mediated transport to the plasma membrane#GO:0098876;regulation of catabolic process#GO:0009894;intracellular transport#GO:0046907;regulation of response to stimulus#GO:0048583;transport#GO:0006810;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;localization#GO:0051179;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;localization within membrane#GO:0051668;positive regulation of macromolecule metabolic process#GO:0010604;vesicle-mediated transport#GO:0016192;regulation of protein metabolic process#GO:0051246;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;endosomal transport#GO:0016197;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;endocytic recycling#GO:0032456;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;cellular localization#GO:0051641;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247 GORGO|Ensembl=ENSGGOG00000013001.3|UniProtKB=G3RB47 G3RB47 NEK3 PTHR44984:SF1 SERINE/THREONINE-PROTEIN KINASE NEK3 SERINE_THREONINE-PROTEIN KINASE NEK3 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000001040.3|UniProtKB=G3QFF2 G3QFF2 SLC22A5 PTHR24064:SF283 SOLUTE CARRIER FAMILY 22 MEMBER ORGANIC CATION_CARNITINE TRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;quaternary ammonium group transmembrane transporter activity#GO:0015651 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000041982.1|UniProtKB=A0A2I2Z159 A0A2I2Z159 PTHR23267:SF514 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-16-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000022061.2|UniProtKB=G3RPT2 G3RPT2 PTHR11205:SF33 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000002102.3|UniProtKB=G3QI67 G3QI67 PDGFD PTHR11633:SF4 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR D signaling receptor binding#GO:0005102;binding#GO:0005488;growth factor receptor binding#GO:0070851;protein binding#GO:0005515 regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of locomotion#GO:0040017;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of ERK1 and ERK2 cascade#GO:0070372;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224 GORGO|Ensembl=ENSGGOG00000036182.1|UniProtKB=A0A2I2ZD15 A0A2I2ZD15 CLDN4 PTHR12002:SF89 CLAUDIN CLAUDIN-4 cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;localization#GO:0051179;cellular component biogenesis#GO:0044085;renal system process#GO:0003014;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;transport#GO:0006810;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;renal absorption#GO:0070293;system process#GO:0003008 tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000001635.3|UniProtKB=G3QGZ4 G3QGZ4 BCAR3 PTHR14247:SF10 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 positive regulation of response to stimulus#GO:0048584;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to peptide hormone#GO:0043434;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to chemical#GO:0042221;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;regulation of signaling#GO:0023051 GORGO|Ensembl=ENSGGOG00000012048.3|UniProtKB=G3R8P3 G3R8P3 IL1RAP PTHR11890:SF20 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000041206.1|UniProtKB=G3R5Z4 G3R5Z4 PTHR23262:SF182 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-2 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000016629.3|UniProtKB=A0A2I2YJC0 A0A2I2YJC0 ZNF775 PTHR24393:SF184 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 775 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010015.3|UniProtKB=A0A2I2ZIY1 A0A2I2ZIY1 MOB1A PTHR22599:SF30 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 1A protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;hippo signaling#GO:0035329;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 kinase activator#PC00138 CCKR signaling map#P06959>MOB1#G07283;CCKR signaling map#P06959>MOB1#G06990 GORGO|Ensembl=ENSGGOG00000015056.3|UniProtKB=G3RSN8 G3RSN8 PTHR12247:SF78 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 4 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000039503.1|UniProtKB=A0A2I2ZZ00 A0A2I2ZZ00 PTHR10442:SF24 40S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN ES21 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;protein metabolic process#GO:0019538;translation#GO:0006412;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012714.3|UniProtKB=G3RAC9 G3RAC9 VEGFA PTHR12025:SF5 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR A, LONG FORM signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;blood vessel morphogenesis#GO:0048514;response to abiotic stimulus#GO:0009628;response to endogenous stimulus#GO:0009719;vascular endothelial growth factor receptor signaling pathway#GO:0048010;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;positive regulation of response to external stimulus#GO:0032103;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of chemotaxis#GO:0050921;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte migration#GO:0002685;response to growth factor#GO:0070848;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of locomotion#GO:0040017;response to hypoxia#GO:0001666;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;tube development#GO:0035295;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 VEGF signaling pathway#P00056>VEGF#P01406;Angiogenesis#P00005>VEGF#P00241 GORGO|Ensembl=ENSGGOG00000011462.3|UniProtKB=G3R753 G3R753 GLTPD2 PTHR10219:SF19 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN DOMAIN-CONTAINING PROTEIN 2 transporter activity#GO:0005215;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;molecular carrier activity#GO:0140104;ion binding#GO:0043167;lipid carrier activity#GO:0005319;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;phospholipid transfer activity#GO:0120014 lipid transport#GO:0006869;membrane organization#GO:0061024;ceramide transport#GO:0035627;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;lipid localization#GO:0010876;transport#GO:0006810 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000017058.3|UniProtKB=G3RLJ8 G3RLJ8 MIGA1 PTHR21508:SF3 MITOGUARDIN MITOGUARDIN 1 organelle fusion#GO:0048284;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular component organization#GO:0016043;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000011272.3|UniProtKB=G3R6M9 G3R6M9 WNT1 PTHR12027:SF91 WNT RELATED PROTO-ONCOGENE WNT-1 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102 biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell fate commitment#GO:0045165;system development#GO:0048731;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 GORGO|Ensembl=ENSGGOG00000007092.3|UniProtKB=G3QVZ4 G3QVZ4 SSPN PTHR15260:SF1 SARCOSPAN SARCOSPAN sarcolemma#GO:0042383;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000004666.3|UniProtKB=G3QPS3 G3QPS3 PTHR23039:SF3 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000016668.3|UniProtKB=G3SH16 G3SH16 SLC34A2 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B symporter activity#GO:0015293;phosphate transmembrane transporter activity#GO:0005315;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 phosphate ion transport#GO:0006817;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698 apical part of cell#GO:0045177;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;vesicle#GO:0031982;cell periphery#GO:0071944;brush border#GO:0005903;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000025115.2|UniProtKB=G3RTP8 G3RTP8 SIRT5 PTHR11085:SF24 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;NAD-dependent protein lysine deacetylase activity#GO:0034979;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;deacetylase activity#GO:0019213;hydrolase activity#GO:0016787;histone modifying activity#GO:0140993 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000003300.3|UniProtKB=G3QL96 G3QL96 ERCC8 PTHR46202:SF1 DNA EXCISION REPAIR PROTEIN ERCC-8 DNA EXCISION REPAIR PROTEIN ERCC-8 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 response to stress#GO:0006950;cellular process#GO:0009987;protein ubiquitination#GO:0016567;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 nucleus#GO:0005634;protein-containing complex#GO:0032991;nucleotide-excision repair complex#GO:0000109;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000024007.2|UniProtKB=G3S013 G3S013 LOC101135843 PTHR45027:SF5 PUTATIVE GLUTATHIONE HYDROLASE LIGHT CHAIN GLUTATHIONE HYDROLASE LIGHT CHAIN 2-RELATED hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000000193.3|UniProtKB=G3RP36 G3RP36 ANO4 PTHR12308:SF28 ANOCTAMIN ANOCTAMIN-4 intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215 cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000001184.3|UniProtKB=G3QFT7 G3QFT7 ERICH5 PTHR23006:SF0 GLUTAMATE-RICH PROTEIN 5 GLUTAMATE-RICH PROTEIN 5 GORGO|Ensembl=ENSGGOG00000001726.3|UniProtKB=A0A2I2ZST0 A0A2I2ZST0 ARMC10 PTHR15712:SF19 ARMADILLO REPEAT CONTAINING PROTEIN ARMADILLO REPEAT-CONTAINING PROTEIN 10 establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;axonal transport#GO:0098930;organelle localization#GO:0051640;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;axo-dendritic transport#GO:0008088;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000568.3|UniProtKB=G3QE71 G3QE71 IHO1 PTHR35662:SF1 INTERACTOR OF HORMAD1 PROTEIN 1 INTERACTOR OF HORMAD1 PROTEIN 1 chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;DNA metabolic process#GO:0006259;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;meiotic DNA double-strand break formation#GO:0042138;organelle organization#GO:0006996;organelle fission#GO:0048285;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049 intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000023468.2|UniProtKB=G3SGH8 G3SGH8 WFDC12 PTHR19441:SF42 WAP four-disulfide core domain protein WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 12 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000009659.3|UniProtKB=G3R2I7 G3R2I7 F12 PTHR24253:SF26 TRANSMEMBRANE PROTEASE SERINE COAGULATION FACTOR XII serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009544.3|UniProtKB=G3R280 G3R280 SETD6 PTHR13271:SF34 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE N-LYSINE METHYLTRANSFERASE SETD6 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 transferase#PC00220;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000001909.3|UniProtKB=G3QHP3 G3QHP3 PRF1 PTHR46096:SF3 PERFORIN-1 PERFORIN-1 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 leukocyte activation#GO:0045321;defense response to virus#GO:0051607;leukocyte mediated cytotoxicity#GO:0001909;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;T cell mediated immunity#GO:0002456;cell activation#GO:0001775;cell recognition#GO:0008037;leukocyte mediated immunity#GO:0002443;response to virus#GO:0009615;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;cellular process#GO:0009987;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;response to other organism#GO:0051707;adaptive immune response#GO:0002250;cell killing#GO:0001906;immune effector process#GO:0002252;response to external stimulus#GO:0009605;cell-cell recognition#GO:0009988;defense response#GO:0006952 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000002149.3|UniProtKB=G3QIB1 G3QIB1 EDARADD PTHR28469:SF1 ECTODYSPLASIN-A RECEPTOR-ASSOCIATED ADAPTER PROTEIN ECTODYSPLASIN-A RECEPTOR-ASSOCIATED ADAPTER PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008838.3|UniProtKB=G3R0F6 G3R0F6 SIRT6 PTHR11085:SF19 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-6 histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;transcription regulator activity#GO:0140110;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;NAD-dependent protein lysine deacetylase activity#GO:0034979;catalytic activity, acting on a protein#GO:0140096;transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;histone deacetylase activity#GO:0004407;transcription corepressor activity#GO:0003714;deacylase activity#GO:0160215;catalytic activity#GO:0003824 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000005418.3|UniProtKB=G3QRQ0 G3QRQ0 P2RY11 PTHR24231:SF46 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 11 neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010134.3|UniProtKB=G3R3Q9 G3R3Q9 TSKS PTHR14351:SF1 TESTIS-SPECIFIC SERINE KINASE SUBSTRATE TESTIS-SPECIFIC SERINE KINASE SUBSTRATE sexual reproduction#GO:0019953;developmental process#GO:0032502;spermatogenesis#GO:0007283;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000005834.3|UniProtKB=G3QSS0 G3QSS0 RUNDC3A PTHR46251:SF4 RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 RUN DOMAIN-CONTAINING PROTEIN 3A GORGO|Ensembl=ENSGGOG00000011575.3|UniProtKB=G3R7E8 G3R7E8 SPSB1 PTHR12245:SF8 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000028532.2|UniProtKB=G3QPU9 G3QPU9 PTHR22534:SF5 SRCR DOMAIN-CONTAINING PROTEIN IMD DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000013149.3|UniProtKB=G3RBH0 G3RBH0 LCA5L PTHR16650:SF9 C21ORF13-RELATED LEBERCILIN-LIKE PROTEIN microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000005222.4|UniProtKB=Q0MQD7 Q0MQD7 NDUFB5 PTHR13178:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SGDH SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 5, MITOCHONDRIAL respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000042896.1|UniProtKB=A0A2I2ZIP7 A0A2I2ZIP7 LOC101154053 PTHR12010:SF26 40S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN US14 cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;zinc ion binding#GO:0008270 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000005693.3|UniProtKB=G3SB91 G3SB91 TAF15 PTHR23238:SF25 RNA BINDING PROTEIN TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;RNA binding#GO:0003723 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006184.3|UniProtKB=G3QTM0 G3QTM0 CHCHD1 PTHR31278:SF2 CHCHD1 SMALL RIBOSOMAL SUBUNIT PROTEIN MS37 GORGO|Ensembl=ENSGGOG00000012784.3|UniProtKB=G3RAJ5 G3RAJ5 RBSN PTHR13510:SF44 FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED RABENOSYN-5 GORGO|Ensembl=ENSGGOG00000009493.3|UniProtKB=G3R235 G3R235 SMIM5 PTHR37344:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 5 SMALL INTEGRAL MEMBRANE PROTEIN 5 GORGO|Ensembl=ENSGGOG00000038821.1|UniProtKB=A0A2I2YM23 A0A2I2YM23 PTHR11627:SF51 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332;lyase activity#GO:0016829 nicotinamide nucleotide metabolic process#GO:0046496;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 lyase#PC00144;aldolase#PC00044 GORGO|Ensembl=ENSGGOG00000009174.3|UniProtKB=G3SBP4 G3SBP4 EDA2R PTHR12120:SF8 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 27 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;signaling#GO:0023052;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000043699.1|UniProtKB=A0A2I2Z1X8 A0A2I2Z1X8 POLH PTHR45873:SF1 DNA POLYMERASE ETA DNA POLYMERASE ETA catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA-directed DNA polymerase activity#GO:0003887 translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;response to stress#GO:0006950;response to radiation#GO:0009314;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;DNA synthesis involved in DNA replication#GO:0090592;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187 site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;replication fork#GO:0005657;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000013671.3|UniProtKB=G3RCV0 G3RCV0 TCL1B PTHR14060:SF2 PROTEIN P13 MTCP-1 T-CELL LEUKEMIA_LYMPHOMA PROTEIN 1B molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 GORGO|Ensembl=ENSGGOG00000024502.2|UniProtKB=G3S5H5 G3S5H5 PTHR16684:SF13 CENTROMERE PROTEIN C CENTROMERE PROTEIN C nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690 mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;kinetochore assembly#GO:0051382;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;cellular process#GO:0009987;attachment of spindle microtubules to kinetochore#GO:0008608;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779 centromere DNA-binding protein#PC00071 GORGO|Ensembl=ENSGGOG00000011398.3|UniProtKB=G3R6Y9 G3R6Y9 SDC2 PTHR10915:SF6 SYNDECAN SYNDECAN-2 neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;generation of neurons#GO:0048699;regulation of synapse organization#GO:0050807;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;neuron development#GO:0048666;dendrite development#GO:0016358;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;regulation of cell junction assembly#GO:1901888;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;dendrite morphogenesis#GO:0048813;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006874.3|UniProtKB=G3RPK0 G3RPK0 TRIM52 PTHR24103:SF685 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM52 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000007716.3|UniProtKB=G3RQW3 G3RQW3 CD247 PTHR10035:SF2 T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN cell communication#GO:0007154;regulation of immune response#GO:0050776;immune system process#GO:0002376;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 T cell activation#P00053>TCR zeta#P01296 GORGO|Ensembl=ENSGGOG00000028194.2|UniProtKB=G3SGN1 G3SGN1 HAS1 PTHR22913:SF4 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;aminoglycan metabolic process#GO:0006022;extracellular structure organization#GO:0043062;polysaccharide biosynthetic process#GO:0000271;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;cellular component organization#GO:0016043;aminoglycan biosynthetic process#GO:0006023;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;cellular component organization or biogenesis#GO:0071840;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;cellular component assembly#GO:0022607;extracellular matrix assembly#GO:0085029;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000010250.3|UniProtKB=G3R420 G3R420 DDX51 PTHR24031:SF68 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX51 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008127.3|UniProtKB=G3RQ99 G3RQ99 SALL3 PTHR23233:SF46 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000014559.3|UniProtKB=G3RF59 G3RF59 WDR59 PTHR46170:SF1 GATOR COMPLEX PROTEIN WDR59 GATOR2 COMPLEX PROTEIN WDR59 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of TORC1 signaling#GO:1903432;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;cellular response to amino acid starvation#GO:0034198;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to stress#GO:0006950;positive regulation of TORC1 signaling#GO:1904263;response to nutrient levels#GO:0031667;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;Seh1-associated complex#GO:0035859;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001425.3|UniProtKB=G3QGF0 G3QGF0 KLK8 PTHR24271:SF62 KALLIKREIN-RELATED KALLIKREIN-8 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000026101.2|UniProtKB=G3S3L5 G3S3L5 TMEM35B PTHR13163:SF2 SPINAL CORD EXPRESSION PROTEIN 4 TRANSMEMBRANE PROTEIN 35B chaperone-mediated protein complex assembly#GO:0051131;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;biological regulation#GO:0065007;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000038775.1|UniProtKB=A0A2I2Y1Z9 A0A2I2Y1Z9 DUSP7 PTHR10159:SF305 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 7 protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of response to stimulus#GO:0048585;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000042323.1|UniProtKB=A0A2I2ZVQ8 A0A2I2ZVQ8 PTHR23147:SF137 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 10 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000003842.3|UniProtKB=G3QMN6 G3QMN6 KDM7A PTHR23123:SF15 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 7A protein demethylase activity#GO:0140457;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone demethylase activity#GO:0032452 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000002344.3|UniProtKB=G3QIT9 G3QIT9 JADE1 PTHR13793:SF79 PHD FINGER PROTEINS PROTEIN JADE-1 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000012939.3|UniProtKB=G3RAZ2 G3RAZ2 GAB4 PTHR45960:SF4 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 4 receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005665.3|UniProtKB=G3QSB7 G3QSB7 FBP2 PTHR11556:SF13 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE ISOZYME 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987;hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;glucose metabolic process#GO:0006006 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 phosphatase#PC00181;carbohydrate phosphatase#PC00066;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000042563.1|UniProtKB=A0A2I2Y700 A0A2I2Y700 CFAP45 PTHR15504:SF1 NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45 flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;regulation of microtubule-based process#GO:0032886;regulation of biological quality#GO:0065008;regulation of cell motility#GO:2000145;cilium-dependent cell motility#GO:0060285;sperm motility#GO:0097722;regulation of biological process#GO:0050789;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;cell motility#GO:0048870;microtubule-based movement#GO:0007018;regulation of microtubule-based movement#GO:0060632 axoneme#GO:0005930;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoplasmic microtubule#GO:0005881;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000015581.3|UniProtKB=G3RHS3 G3RHS3 LCP1 PTHR19961:SF35 FIMBRIN/PLASTIN PLASTIN-2 binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092 actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;actin filament#GO:0005884;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000003577.3|UniProtKB=G3QLZ7 G3QLZ7 CAMTA1 PTHR23335:SF11 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 1 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000038070.1|UniProtKB=A0A2I2Y8Q2 A0A2I2Y8Q2 PTHR23413:SF19 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N 60S RIBOSOMAL PROTEIN L32 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000022993.2|UniProtKB=G3RSR4 G3RSR4 PGAP4 PTHR31410:SF1 TRANSMEMBRANE PROTEIN 246 GPI-N-ACETYLGALACTOSAMINE TRANSFERASE PGAP4 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000003442.3|UniProtKB=G3QLM8 G3QLM8 PTHR13589:SF4 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 3 transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488;transcription coregulator activity#GO:0003712;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription coactivator activity#GO:0003713 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell communication#GO:0010648;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000014598.3|UniProtKB=G3RF85 G3RF85 RTKN PTHR21538:SF19 ANILLIN/RHOTEKIN RTKN RHOTEKIN enzyme inhibitor activity#GO:0004857;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 actomyosin contractile ring assembly#GO:0000915;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;septin cytoskeleton organization#GO:0032185;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actomyosin structure organization#GO:0031032;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;actin filament-based process#GO:0030029;cytokinetic process#GO:0032506;septin ring organization#GO:0031106;cortical actin cytoskeleton organization#GO:0030866;cytoskeleton-dependent cytokinesis#GO:0061640 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;contractile ring#GO:0070938;actomyosin contractile ring#GO:0005826;membraneless organelle#GO:0043228;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000023735.2|UniProtKB=G3SDK2 G3SDK2 PTHR23215:SF5 ZINC FINGER PROTEIN 207 C2H2-TYPE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of sister chromatid segregation#GO:0033046;cellular component organization or biogenesis#GO:0071840;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;mitotic spindle organization#GO:0007052;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;negative regulation of biological process#GO:0048519;sister chromatid segregation#GO:0000819;negative regulation of cell cycle phase transition#GO:1901988;nuclear chromosome segregation#GO:0098813;nuclear division#GO:0000280;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;mitotic spindle assembly checkpoint signaling#GO:0007094;spindle assembly#GO:0051225;attachment of spindle microtubules to kinetochore#GO:0008608;microtubule-based process#GO:0007017;negative regulation of cell cycle#GO:0045786;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;regulation of mitotic cell cycle#GO:0007346;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic nuclear division#GO:0007088;spindle organization#GO:0007051;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;mitotic cell cycle checkpoint signaling#GO:0007093;microtubule cytoskeleton organization involved in mitosis#GO:1902850;negative regulation of cellular component organization#GO:0051129;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;negative regulation of chromosome organization#GO:2001251;organelle localization#GO:0051640 condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000022458.2|UniProtKB=A0A2I2ZB95 A0A2I2ZB95 AK9 PTHR23359:SF148 NUCLEOTIDE KINASE ADENYLATE KINASE 9 nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000028531.2|UniProtKB=G3RTF7 G3RTF7 FBXL14 PTHR13318:SF273 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 14 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000003869.3|UniProtKB=G3QMR1 G3QMR1 CARMIL2 PTHR24112:SF32 LEUCINE-RICH REPEAT, ISOFORM F-RELATED CAPPING PROTEIN, ARP2_3 AND MYOSIN-I LINKER PROTEIN 2 cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000008582.3|UniProtKB=A0A2I2ZPV9 A0A2I2ZPV9 TSACC PTHR37368:SF1 TSSK6-ACTIVATING CO-CHAPERONE PROTEIN TSSK6-ACTIVATING CO-CHAPERONE PROTEIN protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of metabolic process#GO:0009893 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein folding chaperone complex#GO:0101031 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000003197.3|UniProtKB=G3QL07 G3QL07 VCP PTHR23077:SF69 AAA-FAMILY ATPASE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;polyubiquitin modification-dependent protein binding#GO:0031593;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;modification-dependent protein binding#GO:0140030;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;microtubule cytoskeleton organization#GO:0000226;protein metabolic process#GO:0019538;localization#GO:0051179;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;microtubule cytoskeleton organization involved in mitosis#GO:1902850;primary metabolic process#GO:0044238;cell cycle#GO:0007049;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;transport#GO:0006810;autophagosome maturation#GO:0097352;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;spindle organization#GO:0007051;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;cell cycle process#GO:0022402;cellular component organization#GO:0016043;mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagy#GO:0006914;establishment of protein localization#GO:0045184;response to stress#GO:0006950;organelle organization#GO:0006996;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;response to chemical#GO:0042221 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008292.3|UniProtKB=G3QZ09 G3QZ09 ORMDL3 PTHR12665:SF11 ORMDL PROTEINS ORM1-LIKE PROTEIN 3 homeostatic process#GO:0042592;cellular process#GO:0009987;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;ceramide metabolic process#GO:0006672;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665 protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000041304.1|UniProtKB=A0A2I2YDG2 A0A2I2YDG2 PTHR11695:SF652 ALCOHOL DEHYDROGENASE RELATED NAD(P)H OXIDOREDUCTASE RTN4IP1, MITOCHONDRIAL oxidoreductase activity, acting on NAD(P)H#GO:0016651;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000041914.1|UniProtKB=A0A2I2YEH1 A0A2I2YEH1 SMIM22 PTHR36982:SF3 CLCA DOMAIN-CONTAINING PROTEIN SMALL INTEGRAL MEMBRANE PROTEIN 22 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000024135.2|UniProtKB=G3RUU5 G3RUU5 CRIP2 PTHR24215:SF29 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE-RICH PROTEIN 2 cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000010747.3|UniProtKB=G3R5B0 G3R5B0 M6PR PTHR15071:SF29 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-DEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR binding#GO:0005488;protein-containing complex binding#GO:0044877 protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;protein localization to vacuole#GO:0072665;lysosomal transport#GO:0007041;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;establishment of protein localization to vacuole#GO:0072666;protein localization to lysosome#GO:0061462;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;late endosome#GO:0005770;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000002202.3|UniProtKB=G3QIG0 G3QIG0 PTHR31254:SF1 HYPOTHETICAL PROTEIN LOC690617 TEKTIN BUNDLE-INTERACTING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000024080.2|UniProtKB=G3SDA8 G3SDA8 C23H22orf23 PTHR28348:SF1 UPF0193 PROTEIN EVG1 UPF0193 PROTEIN EVG1 GORGO|Ensembl=ENSGGOG00000012593.3|UniProtKB=G3RA25 G3RA25 PTHR23235:SF16 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 Huntington disease#P00029>Sp1#P00803;Gonadotropin-releasing hormone receptor pathway#P06664>SP1#P06846;CCKR signaling map#P06959>SP1#P07203 GORGO|Ensembl=ENSGGOG00000000783.3|UniProtKB=G3QES2 G3QES2 TRMT2A PTHR45904:SF2 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000043794.1|UniProtKB=G3RZ65 G3RZ65 CLDN24 PTHR12002:SF84 CLAUDIN CLAUDIN-24 cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000007616.3|UniProtKB=G3QXB0 G3QXB0 SPIN1 PTHR10405:SF15 SPINDLIN SPINDLIN-1 histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;chromatin-protein adaptor activity#GO:0140463 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000040431.1|UniProtKB=A0A2I2YNM2 A0A2I2YNM2 PTHR11193:SF5 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933 U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000007291.3|UniProtKB=G3QWI0 G3QWI0 RNF115 PTHR22765:SF422 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING-TYPE E3 UBIQUITIN TRANSFERASE acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010498.3|UniProtKB=G3R4N2 G3R4N2 TTI2 PTHR32226:SF2 TELO2-INTERACTING PROTEIN 2 TELO2-INTERACTING PROTEIN 2 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000011506.3|UniProtKB=G3R797 G3R797 IL27RA PTHR48423:SF1 INTERLEUKIN-27 RECEPTOR SUBUNIT ALPHA INTERLEUKIN-27 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000016254.3|UniProtKB=A0A2I2Y7N6 A0A2I2Y7N6 UBQLN1 PTHR10677:SF16 UBIQUILIN UBIQUILIN-1 polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488;protein binding#GO:0005515 response to stimulus#GO:0050896;cellular component organization#GO:0016043;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular component assembly#GO:0022607;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;regulation of macroautophagy#GO:0016241;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;vacuole organization#GO:0007033;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;organelle assembly#GO:0070925;macroautophagy#GO:0016236;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027557.2|UniProtKB=G3RVM4 G3RVM4 KLRK1 PTHR22800:SF185 C-TYPE LECTIN PROTEINS NKG2-F TYPE II INTEGRAL MEMBRANE PROTEIN signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 defense response#GO:0006952;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;response to other organism#GO:0051707;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;activation of innate immune response#GO:0002218;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of response to biotic stimulus#GO:0002831;positive regulation of natural killer cell mediated immunity#GO:0002717;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of natural killer cell mediated immunity#GO:0002715;cellular response to stimulus#GO:0051716;regulation of leukocyte mediated immunity#GO:0002703;innate immune response-activating signaling pathway#GO:0002758;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;signal transduction#GO:0007165;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;natural killer cell mediated immunity#GO:0002228;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014622.4|UniProtKB=G3RFA7 G3RFA7 SLCO1C1 PTHR11388:SF99 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1C1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016303.3|UniProtKB=A0A2I2ZFT9 A0A2I2ZFT9 FAM240C PTHR40387:SF4 PROTEIN FAM240B PROTEIN FAM240C GORGO|Ensembl=ENSGGOG00000040642.1|UniProtKB=G3S4Y3 G3S4Y3 LOC101149806 PTHR26454:SF79 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C75 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001544.3|UniProtKB=G3QGR5 G3QGR5 FLCN PTHR31441:SF4 FOLLICULIN FAMILY MEMBER FOLLICULIN enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of signaling#GO:0023056;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of TORC1 signaling#GO:1903432;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of TOR signaling#GO:0032008;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000040461.1|UniProtKB=A0A2I2Z093 A0A2I2Z093 EIF5 PTHR23001:SF22 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 5 translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;translation initiation factor binding#GO:0031369;binding#GO:0005488;protein binding#GO:0005515;enzyme regulator activity#GO:0030234 biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000000184.3|UniProtKB=G3RTQ0 G3RTQ0 PTHR15025:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-6 SUBUNIT ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762 membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cation channel complex#GO:0034703;sarcolemma#GO:0042383;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016937.3|UniProtKB=G3RL88 G3RL88 PTTG1 PTHR10418:SF7 SECURIN-3 SECURIN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869 organelle organization#GO:0006996;cellular process#GO:0009987;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;meiotic chromosome segregation#GO:0045132;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;reproductive process#GO:0022414;cell cycle#GO:0007049;meiosis I#GO:0007127;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sexual reproduction#GO:0019953 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000034812.2|UniProtKB=G3SKT1 G3SKT1 NEXN PTHR10075:SF52 BASIGIN RELATED NEXILIN focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;myofibril#GO:0030016;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;I band#GO:0031674;membraneless organelle#GO:0043228;cell junction#GO:0030054;sarcomere#GO:0030017 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000003736.3|UniProtKB=G3QMD5 G3QMD5 ZNF607 PTHR23226:SF412 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015628.3|UniProtKB=A0A2I2YF24 A0A2I2YF24 NEDD4 PTHR11254:SF282 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD4 transferase activity#GO:0016740;catalytic activity#GO:0003824;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;transporter regulator activity#GO:0141108;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247 anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;protein metabolic process#GO:0019538;localization#GO:0051179;system development#GO:0048731;synapse organization#GO:0050808;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;cell junction organization#GO:0034330;catabolic process#GO:0009056;regulation of developmental process#GO:0050793;primary metabolic process#GO:0044238;regulation of dendrite morphogenesis#GO:0048814;modification-dependent protein catabolic process#GO:0019941;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;neurogenesis#GO:0022008;receptor-mediated endocytosis#GO:0006898;regulation of cell projection organization#GO:0031344;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;neuron development#GO:0048666;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;modification-dependent macromolecule catabolic process#GO:0043632;regulation of synapse organization#GO:0050807;protein catabolic process#GO:0030163;generation of neurons#GO:0048699;endocytosis#GO:0006897;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of anatomical structure morphogenesis#GO:0022603;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuromuscular junction development#GO:0007528;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;neuron differentiation#GO:0030182;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;neuron projection development#GO:0031175;receptor internalization#GO:0031623;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 GORGO|Ensembl=ENSGGOG00000002448.3|UniProtKB=G3QJ27 G3QJ27 AKIRIN2 PTHR13293:SF8 AKIRIN-RELATED AKIRIN-2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of response to biotic stimulus#GO:0002833;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of response to biotic stimulus#GO:0002831;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of response to external stimulus#GO:0032103;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000014683.3|UniProtKB=A0A2I2YXP6 A0A2I2YXP6 F3 PTHR20859:SF22 INTERFERON/INTERLEUKIN RECEPTOR TISSUE FACTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Blood coagulation#P00011>Tissue Factor#P00450;Angiogenesis#P00005>TF#P00191 GORGO|Ensembl=ENSGGOG00000002745.3|UniProtKB=G3QJU8 G3QJU8 C1QBP PTHR10826:SF1 COMPLEMENT COMPONENT 1 COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL protein-RNA adaptor activity#GO:0140517;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 defense/immunity protein#PC00090;complement component#PC00078 GORGO|Ensembl=ENSGGOG00000026832.2|UniProtKB=G3SCH9 G3SCH9 PTHR23266:SF304 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-18 antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000016408.3|UniProtKB=A0A2I2ZA18 A0A2I2ZA18 RAB36 PTHR47977:SF10 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-36 ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000003581.3|UniProtKB=G3QLZ5 G3QLZ5 ODAD4 PTHR23040:SF1 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000965.3|UniProtKB=A0A2I2YXZ5 A0A2I2YXZ5 BRME1 PTHR14583:SF0 UNCHARACTERIZED PROTEIN C19ORF57 FAMILY MEMBER BREAK REPAIR MEIOTIC RECOMBINASE RECRUITMENT FACTOR 1 GORGO|Ensembl=ENSGGOG00000037045.1|UniProtKB=A0A2I2Y7J3 A0A2I2Y7J3 RNF182 PTHR46675:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF182 E3 UBIQUITIN-PROTEIN LIGASE RNF182 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000005432.3|UniProtKB=G3QRQ5 G3QRQ5 TTC22 PTHR16253:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 22 TETRATRICOPEPTIDE REPEAT PROTEIN 22 GORGO|Ensembl=ENSGGOG00000013971.2|UniProtKB=G3RDL7 G3RDL7 LOC101144267 PTHR26453:SF757 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 10 SUBFAMILY K MEMBER 2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007992.3|UniProtKB=G3QY85 G3QY85 AOC2 PTHR10638:SF4 COPPER AMINE OXIDASE AMINE OXIDASE [COPPER-CONTAINING] 2 transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872;copper ion binding#GO:0005507;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;amine metabolic process#GO:0009308;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 oxidoreductase#PC00176;oxidase#PC00175 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 GORGO|Ensembl=ENSGGOG00000004394.4|UniProtKB=G3QP24 G3QP24 DEPTOR PTHR22829:SF18 DEP DOMAIN PROTEIN DEP DOMAIN-CONTAINING MTOR-INTERACTING PROTEIN protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase inhibitor activity#GO:0019210;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme inhibitor activity#GO:0004857;enzyme activator activity#GO:0008047;molecular function inhibitor activity#GO:0140678;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000015900.3|UniProtKB=A0A2I2ZF19 A0A2I2ZF19 LARP1B PTHR22792:SF50 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1B RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000037494.1|UniProtKB=A0A2I2ZQL8 A0A2I2ZQL8 ZNF470 PTHR24381:SF397 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 78 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000004807.3|UniProtKB=A0A2I2Z9C3 A0A2I2Z9C3 CACNA1B PTHR45628:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT N-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1B voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215 trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic cation transmembrane transport#GO:0098655;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;cell body#GO:0044297;transmembrane transporter complex#GO:1902495;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;GABA-B receptor II signaling#P05731>Ca channel#P05753;Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 GORGO|Ensembl=ENSGGOG00000025253.2|UniProtKB=G3RVH8 G3RVH8 LOC101125648 PTHR48002:SF59 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4L1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026748.2|UniProtKB=G3S9D0 G3S9D0 ZNRF1 PTHR46661:SF2 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZNRF1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000015111.3|UniProtKB=A0A2I2ZBM6 A0A2I2ZBM6 LRRC7 PTHR23119:SF48 DISCS LARGE LEUCINE-RICH REPEAT-CONTAINING PROTEIN 7 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;cell adhesion#GO:0007155;receptor clustering#GO:0043113;positive regulation of cellular component organization#GO:0051130;localization within membrane#GO:0051668;positive regulation of cell projection organization#GO:0031346;establishment or maintenance of bipolar cell polarity#GO:0061245;positive regulation of neuron projection development#GO:0010976;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;cellular localization#GO:0051641;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;macromolecule localization#GO:0033036;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;intracellular protein localization#GO:0008104;regulation of plasma membrane bounded cell projection organization#GO:0120035 anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;main axon#GO:0044304;neuron projection#GO:0043005;cell-cell junction#GO:0005911 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011961.3|UniProtKB=G3SF29 G3SF29 TBX10 PTHR11267:SF102 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX10 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 GORGO|Ensembl=ENSGGOG00000023354.2|UniProtKB=G3SAJ0 G3SAJ0 PTHR23267:SF454 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-19-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000001199.3|UniProtKB=A0A2I2ZEV7 A0A2I2ZEV7 GPRC6A PTHR24061:SF5 CALCIUM-SENSING RECEPTOR-RELATED G PROTEIN-COUPLED RECEPTOR FAMILY C GROUP 6 MEMBER A molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013738.3|UniProtKB=G3SD30 G3SD30 XRN2 PTHR12341:SF41 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 2 5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 GORGO|Ensembl=ENSGGOG00000028300.2|UniProtKB=G3RPW5 G3RPW5 PTHR10926:SF1 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000004005.3|UniProtKB=G3QN26 G3QN26 CNMD PTHR14064:SF6 CHONDROMODULIN-RELATED LEUKOCYTE CELL-DERIVED CHEMOTAXIN 1 negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cell population proliferation#GO:0042127;regulation of angiogenesis#GO:0045765;negative regulation of cellular process#GO:0048523;regulation of vasculature development#GO:1901342;regulation of cellular process#GO:0050794;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000003390.3|UniProtKB=G3QLI4 G3QLI4 MAST1 PTHR24356:SF150 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;signal transduction#GO:0007165;organelle organization#GO:0006996;head development#GO:0060322;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;animal gross anatomical part developmental process#GO:0160108;intracellular signal transduction#GO:0035556;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;central nervous system development#GO:0007417 cell body#GO:0044297;microtubule cytoskeleton#GO:0015630;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;neuronal cell body#GO:0043025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000024062.2|UniProtKB=G3RUR9 G3RUR9 PTHR11829:SF209 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN B1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000043224.1|UniProtKB=A0A2I2Y7V2 A0A2I2Y7V2 PTHR23359:SF58 NUCLEOTIDE KINASE ADENYLATE KINASE 4, MITOCHONDRIAL nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776 purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 GORGO|Ensembl=ENSGGOG00000026663.2|UniProtKB=G3RU40 G3RU40 RRS1 PTHR17602:SF4 RIBOSOME BIOGENESIS REGULATORY PROTEIN RIBOSOME BIOGENESIS REGULATORY PROTEIN HOMOLOG ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014499.3|UniProtKB=G3REY8 G3REY8 PTGFR PTHR11866:SF4 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN F2-ALPHA RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of biological quality#GO:0065008;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 GORGO|Ensembl=ENSGGOG00000005239.3|UniProtKB=G3RNY1 G3RNY1 SMTNL1 PTHR23167:SF45 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SMOOTHELIN-LIKE PROTEIN 1 cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015934.3|UniProtKB=G3RIP1 G3RIP1 CTSA PTHR11802:SF502 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE LYSOSOMAL PROTECTIVE PROTEIN catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000010315.3|UniProtKB=G3R469 G3R469 MMP3 PTHR10201:SF215 MATRIX METALLOPROTEINASE STROMELYSIN-1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;cellular process#GO:0009987;catabolic process#GO:0009056 metalloprotease#PC00153 CCKR signaling map#P06959>MMP3#P07105;Plasminogen activating cascade#P00050>pro-MMP-3#P01260;Plasminogen activating cascade#P00050>MMP-3#P01251 GORGO|Ensembl=ENSGGOG00000014474.3|UniProtKB=A0A2I2ZAF9 A0A2I2ZAF9 MTUS1 PTHR24200:SF7 TOUCAN, ISOFORM A MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;regulation of cell motility#GO:2000145;regulation of biological process#GO:0050789;regulation of chemotaxis#GO:0050920;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of leukocyte migration#GO:0002685;regulation of immune system process#GO:0002682;regulation of response to external stimulus#GO:0032101;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000036861.1|UniProtKB=A0A2I2Z5R6 A0A2I2Z5R6 PTHR31817:SF7 FAMILY NOT NAMED KIAA0895 LIKE GORGO|Ensembl=ENSGGOG00000015431.3|UniProtKB=G3RHD4 G3RHD4 OVOL3 PTHR10032:SF220 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS TRANSCRIPTION FACTOR OVO-LIKE PROTEIN 3-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;epidermis development#GO:0008544;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012782.3|UniProtKB=G3RAJ0 G3RAJ0 HYI PTHR43489:SF6 ISOMERASE HYDROXYPYRUVATE ISOMERASE-RELATED isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824 aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 isomerase#PC00135;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000038761.1|UniProtKB=A0A2I2Z842 A0A2I2Z842 PTHR10792:SF44 60S RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN EL24 mRNA binding#GO:0003729;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000861.3|UniProtKB=G3QEZ0 G3QEZ0 RASD2 PTHR46149:SF1 MIP08469P GTP-BINDING PROTEIN RHES binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000005141.3|UniProtKB=G3RS44 G3RS44 PKMYT1 PTHR11042:SF183 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 reproductive process#GO:0022414;meiotic cell cycle#GO:0051321;cell cycle#GO:0007049;sexual reproduction#GO:0019953;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003199.3|UniProtKB=G3QL06 G3QL06 GNG3 PTHR13809:SF11 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-3 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;catalytic complex#GO:1902494 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;GABA-B receptor II signaling#P05731>Ggamma#P05754;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448 GORGO|Ensembl=ENSGGOG00000003942.3|UniProtKB=G3QMX0 G3QMX0 LGSN PTHR43407:SF1 GLUTAMINE SYNTHETASE LENGSIN ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 homeostatic process#GO:0042592;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;response to nutrient levels#GO:0031667;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;chemical homeostasis#GO:0048878;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483 GORGO|Ensembl=ENSGGOG00000001315.3|UniProtKB=G3QG46 G3QG46 TMEM121 PTHR31046:SF0 TRANSMEMBRANE PROTEIN 121 TRANSMEMBRANE PROTEIN 121 GORGO|Ensembl=ENSGGOG00000006754.3|UniProtKB=A0A2I2ZTF1 A0A2I2ZTF1 TMF1 PTHR46515:SF1 TATA ELEMENT MODULATORY FACTOR TMF1 TATA ELEMENT MODULATORY FACTOR Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000002866.3|UniProtKB=G3QK55 G3QK55 ZFR2 PTHR45762:SF2 ZINC FINGER RNA-BINDING PROTEIN ZINC FINGER RNA-BINDING PROTEIN 2 double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000043936.1|UniProtKB=G3RVL7 G3RVL7 LOC101123860 PTHR23428:SF77 HISTONE H2B HISTONE H2B TYPE 1-A chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000014938.3|UniProtKB=G3S809 G3S809 CHCHD2 PTHR13523:SF3 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 2-RELATED DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000013491.3|UniProtKB=A0A2I2ZDZ6 A0A2I2ZDZ6 CASD1 PTHR13533:SF53 N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE N-ACETYLNEURAMINATE (7)9-O-ACETYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 acetyltransferase#PC00038;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000024818.2|UniProtKB=G3S685 G3S685 ORC3 PTHR12748:SF1 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 binding#GO:0005488;DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;nuclear pre-replicative complex#GO:0005656;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nuclear origin of replication recognition complex#GO:0005664;membraneless organelle#GO:0043228;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;organelle lumen#GO:0043233;DNA replication preinitiation complex#GO:0031261;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;pre-replicative complex#GO:0036387;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 GORGO|Ensembl=ENSGGOG00000022853.2|UniProtKB=A0A2I2YGR5 A0A2I2YGR5 LOC101153946 PTHR24071:SF43 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule biosynthetic process#GO:0009059;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;transport#GO:0006810;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;RNA export from nucleus#GO:0006405;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;ribosome localization#GO:0033750;organelle localization#GO:0051640;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;protein export from nucleus#GO:0006611;gene expression#GO:0010467;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;ribosomal large subunit export from nucleus#GO:0000055;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;ribosome biogenesis#GO:0042254;protein transport#GO:0015031;protein import into nucleus#GO:0006606;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406 intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000044142.1|UniProtKB=A0A2I2YU73 A0A2I2YU73 PTHR10666:SF438 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN ES31 FUSION PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;ribosome#GO:0005840;nucleus#GO:0005634;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000006912.3|UniProtKB=G3QVJ5 G3QVJ5 IDS PTHR45953:SF1 IDURONATE 2-SULFATASE IDURONATE 2-SULFATASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764 GORGO|Ensembl=ENSGGOG00000022778.2|UniProtKB=G3RVF9 G3RVF9 PTHR23267:SF359 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-22 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000022888.2|UniProtKB=G3SHA8 G3SHA8 EPCAM PTHR14168:SF2 TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER EPITHELIAL CELL ADHESION MOLECULE binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 apical junction complex#GO:0043296;extracellular region#GO:0005576;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000001698.3|UniProtKB=G3QH50 G3QH50 PLEKHF1 PTHR46280:SF2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091 cellular component organization#GO:0016043;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;cellular localization#GO:0051641;positive regulation of metabolic process#GO:0009893;localization#GO:0051179;regulation of metabolic process#GO:0019222;positive regulation of autophagy#GO:0010508;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of cellular process#GO:0048522;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;regulation of catabolic process#GO:0009894;vesicle organization#GO:0016050 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole#GO:0000323;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773 GORGO|Ensembl=ENSGGOG00000006665.3|UniProtKB=G3QUX7 G3QUX7 VPS41 PTHR12616:SF1 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular localization#GO:0051641;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;catabolic process#GO:0009056;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular transport#GO:0046907;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;transport#GO:0006810;vacuolar transport#GO:0007034;cellular response to nutrient levels#GO:0031669;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;membrane organization#GO:0061024;response to stress#GO:0006950;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987;autophagy#GO:0006914;establishment of localization in cell#GO:0051649 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;vacuole#GO:0005773;cytoplasm#GO:0005737;vacuolar membrane#GO:0005774;vesicle tethering complex#GO:0099023;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000037091.1|UniProtKB=A0A2I2ZHP0 A0A2I2ZHP0 MTCP1 PTHR14060:SF8 PROTEIN P13 MTCP-1 PROTEIN P13 MTCP-1 kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 GORGO|Ensembl=ENSGGOG00000004471.3|UniProtKB=G3QP97 G3QP97 CDK18 PTHR24056:SF52 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 18 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein serine/threonine kinase activity#GO:0004693 membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006917.3|UniProtKB=G3QVJ9 G3QVJ9 THRAP3 PTHR15268:SF16 THRAP3/BCLAF1 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN 3 transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000023750.2|UniProtKB=G3S2S4 G3S2S4 EMC2 PTHR12760:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000002946.3|UniProtKB=A0A2I2ZKS9 A0A2I2ZKS9 SYCP3 PTHR19368:SF12 XLR/SCP3/FAM9 SYNAPTONEMAL COMPLEX PROTEIN 3 spermatid development#GO:0007286;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;cell cycle#GO:0007049;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell differentiation#GO:0030154;spermatogenesis#GO:0007283;developmental process#GO:0032502;meiotic cell cycle#GO:0051321;cellular developmental process#GO:0048869;cellular process#GO:0009987;male gamete generation#GO:0048232 condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000003081.3|UniProtKB=G3RYG2 G3RYG2 LOC115931052 PTHR36878:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 30 SMALL INTEGRAL MEMBRANE PROTEIN 30 GORGO|Ensembl=ENSGGOG00000002118.3|UniProtKB=G3S1V2 G3S1V2 PTHR12619:SF2 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX7 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000015980.3|UniProtKB=G3RIS1 G3RIS1 NRL PTHR10129:SF24 TRANSCRIPTION FACTOR MAF NEURAL RETINA-SPECIFIC LEUCINE ZIPPER PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 camera-type eye development#GO:0043010;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;visual system development#GO:0150063;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;camera-type eye morphogenesis#GO:0048593;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;sensory organ morphogenesis#GO:0090596;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular process#GO:0009987;sensory system development#GO:0048880;retina development in camera-type eye#GO:0060041;nervous system development#GO:0007399 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000024101.2|UniProtKB=G3QUU9 G3QUU9 LOC101137046 PTHR11639:SF128 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A7 protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 cellular process#GO:0009987;endothelial cell migration#GO:0043542;cell migration#GO:0016477;cell motility#GO:0048870 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000002969.3|UniProtKB=G3QKE5 G3QKE5 PSMD10 PTHR24184:SF27 SI:CH211-189E2.2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000009039.3|UniProtKB=G3R0Y8 G3R0Y8 HGD PTHR11056:SF0 HOMOGENTISATE 1,2-DIOXYGENASE HOMOGENTISATE 1,2-DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000006628.3|UniProtKB=A0A2I2YEQ1 A0A2I2YEQ1 MRI1 PTHR43475:SF1 METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281 isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000042278.1|UniProtKB=A0A2I2YRA6 A0A2I2YRA6 NME6 PTHR46956:SF1 NUCLEOSIDE DIPHOSPHATE KINASE 6 NUCLEOSIDE DIPHOSPHATE KINASE 6, MITOCHONDRIAL nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;negative regulation of cell growth#GO:0030308;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell growth#GO:0001558;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic nuclear division#GO:0007088;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 GORGO|Ensembl=ENSGGOG00000042391.1|UniProtKB=A0A2I2ZVM1 A0A2I2ZVM1 PTHR24068:SF210 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein K11-linked ubiquitination#GO:0070979;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000011010.3|UniProtKB=A0A2I2ZCP5 A0A2I2ZCP5 C20H19orf47 PTHR21359:SF1 DUF5577 DOMAIN-CONTAINING PROTEIN DUF5577 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000002710.3|UniProtKB=G3QJS0 G3QJS0 DES PTHR45652:SF2 GLIAL FIBRILLARY ACIDIC PROTEIN DESMIN structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;muscle structure development#GO:0061061;muscle organ development#GO:0007517;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;myofibril#GO:0030016;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intermediate filament#GO:0005882;cell junction#GO:0030054;sarcomere#GO:0030017;sarcolemma#GO:0042383;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;I band#GO:0031674;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;cell periphery#GO:0071944;Z disc#GO:0030018;cell-cell junction#GO:0005911;membrane#GO:0016020 intermediate filament#PC00129;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000026256.2|UniProtKB=G3S7H5 G3S7H5 CEP83 PTHR23170:SF2 NY-REN-58 ANTIGEN CENTROSOMAL PROTEIN OF 83 KDA cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;organelle localization#GO:0051640;organelle assembly#GO:0070925;centrosome localization#GO:0051642;establishment of organelle localization#GO:0051656;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary transition fiber#GO:0097539;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;Golgi apparatus#GO:0005794;centrosome#GO:0005813;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011180.3|UniProtKB=G3R6F1 G3R6F1 CDH7 PTHR24027:SF91 CADHERIN-23 CADHERIN-7 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell adhesion#GO:0007155;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cell migration#GO:0016477;cellular component assembly#GO:0022607 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000008725.3|UniProtKB=G3R050 G3R050 LOC109024512 PTHR43917:SF4 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-2-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000011852.3|UniProtKB=G3R862 G3R862 PRKD1 PTHR22968:SF9 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE D1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>PRKD1#P07103;EGF receptor signaling pathway#P00018>PKC#P00565;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 GORGO|Ensembl=ENSGGOG00000036587.1|UniProtKB=G3RUE8 G3RUE8 APOBEC3C PTHR13857:SF24 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3D catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;hydrolase activity#GO:0016787 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;base conversion or substitution editing#GO:0016553;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;RNA modification#GO:0009451;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;defense response#GO:0006952;response to external stimulus#GO:0009605;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to external biotic stimulus#GO:0043207;cytidine to uridine editing#GO:0016554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to virus#GO:0009615;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000008503.3|UniProtKB=G3QZJ8 G3QZJ8 GRID2IP PTHR45725:SF3 FORMIN HOMOLOGY 2 FAMILY MEMBER DELPHILIN GORGO|Ensembl=ENSGGOG00000026595.2|UniProtKB=G3SEY0 G3SEY0 PTHR24249:SF405 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 8 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000034888.2|UniProtKB=G3SKK7 G3SKK7 C1QTNF5 PTHR24251:SF60 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000004629.3|UniProtKB=G3QPP3 G3QPP3 A2ML1 PTHR11412:SF182 MACROGLOBULIN / COMPLEMENT ALPHA-2-MACROGLOBULIN-LIKE PROTEIN 1 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 inflammatory response#GO:0006954;response to stress#GO:0006950;defense response#GO:0006952;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000008030.3|UniProtKB=G3QYC3 G3QYC3 RNF175 PTHR13407:SF2 RNF121 PROTEIN RING FINGER PROTEIN 175 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000388.3|UniProtKB=G3RVN5 G3RVN5 ILRUN PTHR20930:SF10 OVARIAN CARCINOMA ANTIGEN CA125-RELATED PROTEIN ILRUN protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;regulation of protein localization#GO:0032880;cellular localization#GO:0051641;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;regulation of localization#GO:0032879;cellular process#GO:0009987;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein targeting to vacuole#GO:0006623;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;protein localization to vacuole#GO:0072665;localization#GO:0051179;negative regulation of multicellular organismal process#GO:0051241;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;transport#GO:0006810;vacuolar transport#GO:0007034;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000034990.2|UniProtKB=G3SKW9 G3SKW9 CAPN8 PTHR10183:SF374 CALPAIN CALPAIN-8 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000024687.2|UniProtKB=A0A2I2Y4W1 A0A2I2Y4W1 TET2 PTHR23358:SF3 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;hemopoiesis#GO:0030097;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transcription by RNA polymerase II#GO:0045944;cell development#GO:0048468;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011207.3|UniProtKB=A0A2I2YX51 A0A2I2YX51 GABRB3 PTHR18945:SF571 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3 chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;channel activity#GO:0015267 signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;cell communication#GO:0007154;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;synaptic signaling#GO:0099536;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821 cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;postsynaptic membrane#GO:0045211;cell junction#GO:0030054 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000016939.3|UniProtKB=G3RL92 G3RL92 ISYNA1 PTHR11510:SF5 MYO-INOSITOL-1 PHOSPHATE SYNTHASE INOSITOL-3-PHOSPHATE SYNTHASE 1 catalytic activity#GO:0003824;isomerase activity#GO:0016853 alcohol biosynthetic process#GO:0046165;small molecule biosynthetic process#GO:0044283;cellular process#GO:0009987;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000038344.1|UniProtKB=A0A2I2Y1P7 A0A2I2Y1P7 ZNF90 PTHR23226:SF313 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 93 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010299.3|UniProtKB=A0A2I2Y939 A0A2I2Y939 H6PD PTHR23429:SF7 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GDH_6PGL ENDOPLASMIC BIFUNCTIONAL PROTEIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;glucose-6-phosphate dehydrogenase activity#GO:0004345;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;generation of precursor metabolites and energy#GO:0006091;pentose-phosphate shunt, oxidative branch#GO:0009051;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000026442.2|UniProtKB=G3S0H0 G3S0H0 ZNF140 PTHR24381:SF483 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 566 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015489.3|UniProtKB=G3RHJ1 G3RHJ1 CFAP221 PTHR46500:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000004911.3|UniProtKB=G3QQE6 G3QQE6 MYL7 PTHR23049:SF39 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2, ATRIAL ISOFORM myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 blood circulation#GO:0008015;heart development#GO:0007507;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;animal organ development#GO:0048513;system process#GO:0003008;heart contraction#GO:0060047;heart process#GO:0003015;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;circulatory system process#GO:0003013;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;system development#GO:0048731 myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;myosin complex#GO:0016459;contractile muscle fiber#GO:0043292 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000001533.4|UniProtKB=G3QGQ2 G3QGQ2 HCN1 PTHR45689:SF3 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 1 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000000549.3|UniProtKB=G3QE55 G3QE55 L3MBTL3 PTHR12247:SF72 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000006474.3|UniProtKB=G3QUD4 G3QUD4 RAD52 PTHR12132:SF1 DNA REPAIR AND RECOMBINATION PROTEIN RAD52, RAD59 DNA REPAIR PROTEIN RAD52 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 double-strand break repair via homologous recombination#GO:0000724;double-strand break repair via single-strand annealing#GO:0045002;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;mitotic recombination#GO:0006312;recombinational repair#GO:0000725;telomere organization#GO:0032200;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;site of double-strand break#GO:0035861;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000000862.3|UniProtKB=G3QEZ3 G3QEZ3 TMEM63A PTHR13018:SF24 PROBABLE MEMBRANE PROTEIN DUF221-RELATED MECHANOSENSITIVE CATION CHANNEL TMEM63A gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000003529.3|UniProtKB=G3QLV2 G3QLV2 KLHDC8A PTHR46260:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 8A GORGO|Ensembl=ENSGGOG00000024780.2|UniProtKB=G3SDA9 G3SDA9 CDKN1B PTHR10265:SF9 CYCLIN-DEPENDENT KINASE INHIBITOR 1 CYCLIN-DEPENDENT KINASE INHIBITOR 1B molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase inhibitor activity#GO:0019210 regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;negative regulation of mitotic cell cycle phase transition#GO:1901991 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase modulator#PC00140;kinase inhibitor#PC00139 Interleukin signaling pathway#P00036>p27KIP1#P00982 GORGO|Ensembl=ENSGGOG00000026697.2|UniProtKB=G3S627 G3S627 RPL17 PTHR11593:SF52 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000039368.1|UniProtKB=A0A2I2Z337 A0A2I2Z337 LOC101144761 PTHR31463:SF7 MACROPHAGE-EXPRESSED GENE 1 PROTEIN MACPF DOMAIN-CONTAINING PROTEIN response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617 GORGO|Ensembl=ENSGGOG00000009788.3|UniProtKB=G3R2U7 G3R2U7 NAA10 PTHR23091:SF268 N-TERMINAL ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 10 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein N-acyltransferase activity#GO:0140186 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein acetyltransferase complex#GO:0031248;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000014081.3|UniProtKB=G3RDW9 G3RDW9 GALP PTHR20950:SF1 GALANIN-RELATED PEPTIDE GALANIN-LIKE PEPTIDE response to stress#GO:0006950;response to nutrient levels#GO:0031667;response to starvation#GO:0042594;response to stimulus#GO:0050896 GORGO|Ensembl=ENSGGOG00000037698.1|UniProtKB=A0A2I2ZGI9 A0A2I2ZGI9 PTHR19343:SF13 T CELL RECEPTOR ALPHA VARIABLE 1-2 IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000013050.3|UniProtKB=G3RB92 G3RB92 ARSH PTHR42693:SF16 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE H hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000016046.3|UniProtKB=G3RIY4 G3RIY4 IRF9 PTHR11949:SF26 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 9 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000022568.2|UniProtKB=G3S3V1 G3S3V1 PTHR47963:SF11 DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL RNA HELICASE RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000001695.3|UniProtKB=G3QH49 G3QH49 PCNA PTHR11352:SF5 PROLIFERATING CELL NUCLEAR ANTIGEN DNA SLIDING CLAMP PCNA molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 DNA biosynthetic process#GO:0071897;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;DNA-templated DNA replication#GO:0006261 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA polymerase processivity factor#PC00015 DNA replication#P00017>PCNA#P00534 GORGO|Ensembl=ENSGGOG00000010246.3|UniProtKB=A0A2I2ZFV9 A0A2I2ZFV9 PAX6 PTHR45636:SF48 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 nervous system development#GO:0007399;head development#GO:0060322;retina development in camera-type eye#GO:0060041;sensory system development#GO:0048880;cellular process#GO:0009987;animal organ development#GO:0048513;multicellular organism development#GO:0007275;forebrain development#GO:0030900;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;brain development#GO:0007420;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;visual system development#GO:0150063;pancreas development#GO:0031016;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;camera-type eye development#GO:0043010 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000000324.3|UniProtKB=G3QDJ7 G3QDJ7 ZBTB37 PTHR24399:SF32 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 37 sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008880.3|UniProtKB=G3R0J4 G3R0J4 NLRP12 PTHR45690:SF11 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;negative regulation of biological process#GO:0048519;positive regulation of biological process#GO:0048518;negative regulation of signal transduction#GO:0009968;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;positive regulation of biosynthetic process#GO:0009891;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000041119.1|UniProtKB=A0A2I2YG73 A0A2I2YG73 STMP1 PTHR47709:SF2 SHORT TRANSMEMBRANE MITOCHONDRIAL PROTEIN 1 SHORT TRANSMEMBRANE MITOCHONDRIAL PROTEIN 1 protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803 GORGO|Ensembl=ENSGGOG00000025973.2|UniProtKB=A1YF16 A1YF16 MSX2 PTHR24338:SF10 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000008983.3|UniProtKB=G3R0T5 G3R0T5 PTHR14057:SF34 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000006204.3|UniProtKB=G3QTP1 G3QTP1 LOC101146257 PTHR11783:SF14 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1B1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000013051.3|UniProtKB=G3RB86 G3RB86 ERICH4 PTHR36879:SF1 GLUTAMATE-RICH PROTEIN 4 GLUTAMATE-RICH PROTEIN 4 GORGO|Ensembl=ENSGGOG00000012622.3|UniProtKB=G3S5Z3 G3S5Z3 MAP3K12 PTHR23257:SF707 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 12 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000027000.2|UniProtKB=A0A2I2YQS4 A0A2I2YQS4 LOC129527246 PTHR10026:SF70 CYCLIN CYCLIN-Q enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138;kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000008329.3|UniProtKB=G3S6K8 G3S6K8 PRC1 PTHR19321:SF1 PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED PROTEIN REGULATOR OF CYTOKINESIS 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;microtubule cytoskeleton organization involved in mitosis#GO:1902850;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000005126.3|UniProtKB=G3RQL4 G3RQL4 TTYH1 PTHR12424:SF5 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 1 channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000006631.3|UniProtKB=G3S0T3 G3S0T3 KIF4A PTHR47969:SF15 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;organelle organization#GO:0006996;cellular process#GO:0009987;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226 microtubule binding motor protein#PC00156;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000001507.3|UniProtKB=G3QGM9 G3QGM9 PIGH PTHR15231:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000004972.3|UniProtKB=G3QQK8 G3QQK8 SEZ6L PTHR45656:SF8 PROTEIN CBR-CLEC-78 SEIZURE 6-LIKE PROTEIN developmental process#GO:0032502;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;nervous system development#GO:0007399;head development#GO:0060322;multicellular organismal process#GO:0032501;brain development#GO:0007420;developmental maturation#GO:0021700;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;cell junction organization#GO:0034330;central nervous system development#GO:0007417 synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;postsynapse#GO:0098794;cell body#GO:0044297;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;postsynaptic membrane#GO:0045211;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;endoplasmic reticulum#GO:0005783;synaptic membrane#GO:0097060 GORGO|Ensembl=ENSGGOG00000008380.3|UniProtKB=G3QZ87 G3QZ87 PPP1R1A PTHR15417:SF4 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1A enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;phosphatase inhibitor#PC00183;phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000028294.2|UniProtKB=G3S404 G3S404 GJD2 PTHR11984:SF32 CONNEXIN GAP JUNCTION DELTA-2 PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070;gap junction#PC00105 GORGO|Ensembl=ENSGGOG00000043176.1|UniProtKB=A0A2I2YUS0 A0A2I2YUS0 PTHR23266:SF376 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000001045.3|UniProtKB=G3RNN2 G3RNN2 DKC1 PTHR23127:SF0 CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1 isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;snRNA processing#GO:0016180;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077;centromere DNA-binding protein#PC00071 GORGO|Ensembl=ENSGGOG00000006652.3|UniProtKB=G3QUV1 G3QUV1 POC1A PTHR44019:SF2 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG A plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000043473.1|UniProtKB=A0A2I2ZJY5 A0A2I2ZJY5 KLC2 PTHR45783:SF2 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 GORGO|Ensembl=ENSGGOG00000005265.3|UniProtKB=G3QRB1 G3QRB1 RAB11FIP5 PTHR15746:SF14 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 5 regulated exocytosis#GO:0045055;transport#GO:0006810;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 recycling endosome#GO:0055037;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;secretory granule#GO:0030141;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;mitochondrion#GO:0005739;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000037578.1|UniProtKB=A0A2I2YSB6 A0A2I2YSB6 PTHR48034:SF18 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA-BINDING MOTIF PROTEIN, X CHROMOSOME RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013323.3|UniProtKB=A0A2I2YWN4 A0A2I2YWN4 AMPD2 PTHR11359:SF3 AMP DEAMINASE AMP DEAMINASE 2 catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137 deaminase#PC00088 GORGO|Ensembl=ENSGGOG00000015294.3|UniProtKB=G3RWF2 G3RWF2 PLK3 PTHR24345:SF42 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;Golgi organization#GO:0007030;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of cell cycle G1/S phase transition#GO:1902806;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;endomembrane system organization#GO:0010256;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;cellular response to stress#GO:0033554;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000009833.3|UniProtKB=G3R2Z5 G3R2Z5 PLD4 PTHR10185:SF8 PHOSPHOLIPASE D - RELATED 5'-3' EXONUCLEASE PLD4 localization#GO:0051179;establishment of localization#GO:0051234;endocytosis#GO:0006897;import into cell#GO:0098657;phagocytosis#GO:0006909;transport#GO:0006810 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000010038.3|UniProtKB=G3R3G8 G3R3G8 ANGPT2 PTHR19143:SF199 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-2 receptor tyrosine kinase binding#GO:0030971;protein binding#GO:0005515;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 signaling#GO:0023052;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;response to stimulus#GO:0050896;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;angiogenesis#GO:0001525;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-2#P00246 GORGO|Gene=TRIM5|UniProtKB=Q5C8T6 Q5C8T6 TRIM5 PTHR24103:SF416 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 5 kinase binding#GO:0019900;binding#GO:0005488;acyltransferase activity#GO:0016746;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein kinase binding#GO:0019901;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;identical protein binding#GO:0042802;aminoacyltransferase activity#GO:0016755 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;positive regulation of signal transduction#GO:0009967;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of protein localization#GO:0032880;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of localization#GO:0032879;defense response to other organism#GO:0098542;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000008333.3|UniProtKB=G3QZ49 G3QZ49 SH3KBP1 PTHR14167:SF6 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001190.3|UniProtKB=G3QFU4 G3QFU4 SNRPA PTHR10501:SF63 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;U1 snRNP#GO:0005685;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 mRNA splicing#P00058>U1#P01479 GORGO|Ensembl=ENSGGOG00000027530.2|UniProtKB=G3SI38 G3SI38 HAUS6 PTHR16151:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 GORGO|Ensembl=ENSGGOG00000006653.3|UniProtKB=G3QUV0 G3QUV0 C1H1orf146 PTHR31408:SF2 HYPOTHETICAL PROTEIN LOC689986 PROTEIN SPO16 HOMOLOG cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;synaptonemal complex assembly#GO:0007130;homologous chromosome pairing at meiosis#GO:0007129;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285 intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000044046.1|UniProtKB=A0A2I2Z1P2 A0A2I2Z1P2 FAXC PTHR12289:SF76 METAXIN RELATED FAILED AXON CONNECTIONS HOMOLOG transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008522.3|UniProtKB=G3QZL8 G3QZL8 GSG1L2 PTHR10671:SF40 EPITHELIAL MEMBRANE PROTEIN-RELATED GERM CELL-SPECIFIC GENE 1-LIKE PROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000024722.2|UniProtKB=G3S2Y1 G3S2Y1 PTHR11880:SF27 RIBOSOMAL PROTEIN S19P FAMILY MEMBER 40S RIBOSOMAL PROTEIN S15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010588.3|UniProtKB=G3R4W6 G3R4W6 MST1 PTHR24261:SF12 PLASMINOGEN-RELATED HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN-RELATED protein binding#GO:0005515;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;binding#GO:0005488;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;receptor tyrosine kinase binding#GO:0030971;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000022218.2|UniProtKB=A0A2I2ZSF6 A0A2I2ZSF6 FAM174A PTHR28607:SF1 EXPRESSED PROTEIN MEMBRANE PROTEIN FAM174A GORGO|Ensembl=ENSGGOG00000012011.3|UniProtKB=G3R8K9 G3R8K9 AIF1 PTHR10356:SF4 ALLOGRAFT INFLAMMATORY FACTOR-1 ALLOGRAFT INFLAMMATORY FACTOR 1 actin binding#GO:0003779;calcium ion binding#GO:0005509;actin filament binding#GO:0051015;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;protein-containing complex binding#GO:0044877;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092 cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;plasma membrane bounded cell projection assembly#GO:0120031 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;leading edge membrane#GO:0031256;intracellular organelle#GO:0043229;cell projection membrane#GO:0031253;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;supramolecular complex#GO:0099080;plasma membrane region#GO:0098590;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;ruffle membrane#GO:0032587;cytoskeleton#GO:0005856;actin filament#GO:0005884;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;ruffle#GO:0001726 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000038561.1|UniProtKB=A0A2I2ZPM1 A0A2I2ZPM1 PTHR19300:SF9 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 4 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 GORGO|Gene=NGF|UniProtKB=Q9N2F0 Q9N2F0 NGF PTHR11589:SF10 NERVE GROWTH FACTOR NGF -RELATED BETA-NERVE GROWTH FACTOR signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;negative regulation of neuron apoptotic process#GO:0043524;neuron projection development#GO:0031175;regulation of neuron apoptotic process#GO:0043523;nervous system development#GO:0007399;regulation of trans-synaptic signaling#GO:0099177;regulation of apoptotic process#GO:0042981;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular response to nerve growth factor stimulus#GO:1990090;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cellular response to endogenous stimulus#GO:0071495;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular response to growth factor stimulus#GO:0071363;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154 cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle#GO:0030133;presynapse#GO:0098793;secretory vesicle#GO:0099503;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;extracellular region#GO:0005576;intracellular organelle#GO:0043229 growth factor#PC00112;neurotrophic factor#PC00163 GORGO|Ensembl=ENSGGOG00000015503.3|UniProtKB=G3RHK1 G3RHK1 EBF4 PTHR10747:SF36 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 P53-like transcription factor#PC00253;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004116.3|UniProtKB=G3QNC9 G3QNC9 CDC45 PTHR10507:SF0 CDC45-RELATED PROTEIN CELL DIVISION CONTROL PROTEIN 45 HOMOLOG chromatin binding#GO:0003682;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA replication origin binding#GO:0003688;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;mitotic cell cycle#GO:0000278;recombinational repair#GO:0000725;double-strand break repair via break-induced replication#GO:0000727;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;cell cycle DNA replication#GO:0044786;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;metabolic process#GO:0008152;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;protein-containing complex organization#GO:0043933 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 GORGO|Ensembl=ENSGGOG00000028007.2|UniProtKB=G3RYX3 G3RYX3 CRHR2 PTHR45620:SF19 PDF RECEPTOR-LIKE PROTEIN-RELATED CORTICOTROPIN-RELEASING HORMONE RECEPTOR 2 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;hormone binding#GO:0042562;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051 dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;cell projection#GO:0042995;neuron projection terminus#GO:0044306;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;synapse#GO:0045202;cellular anatomical structure#GO:0110165;axon terminus#GO:0043679;cell junction#GO:0030054;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;presynapse#GO:0098793;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Cortocotropin releasing factor receptor signaling pathway#P04380>CRHR1#P04451 GORGO|Ensembl=ENSGGOG00000006417.3|UniProtKB=G3QU84 G3QU84 USP43 PTHR21646:SF20 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 43 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000023694.2|UniProtKB=G3RS69 G3RS69 RAB24 PTHR24073:SF471 DRAB5-RELATED RAS-RELATED PROTEIN RAB-24 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;endosome#GO:0005768;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000011284.3|UniProtKB=G3RU28 G3RU28 ZNF503 PTHR12522:SF3 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN 503 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000003002.3|UniProtKB=G3QKH6 G3QKH6 RPL21 PTHR20981:SF8 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010848.3|UniProtKB=G3R5J9 G3R5J9 LTBR PTHR47607:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 3 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 3 ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037236.1|UniProtKB=A0A2I2YV24 A0A2I2YV24 ATP5MF PTHR13080:SF16 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE F(0) COMPLEX SUBUNIT F, MITOCHONDRIAL proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803 ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;oxidative phosphorylation#GO:0006119 cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;proton-transporting ATP synthase complex#GO:0045259;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000011392.3|UniProtKB=G3R6Z2 G3R6Z2 PTHR19302:SF14 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 3 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;cytoplasmic microtubule organization#GO:0031122;reproductive process#GO:0022414;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000007792.3|UniProtKB=G3QXR7 G3QXR7 SIK1 PTHR24346:SF47 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE SIK2-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000037837.1|UniProtKB=A0A2I2ZVE1 A0A2I2ZVE1 GPR26 PTHR24245:SF6 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 26 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000462.3|UniProtKB=G3QDX5 G3QDX5 PXDC1 PTHR31433:SF0 PX DOMAIN-CONTAINING PROTEIN 1 PX DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000040010.1|UniProtKB=A0A2I2ZXU0 A0A2I2ZXU0 PTHR23236:SF42 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4B binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000026954.2|UniProtKB=A0A2I2ZER9 A0A2I2ZER9 FUNDC2 PTHR21346:SF5 FUN14 DOMAIN CONTAINING FUN14 DOMAIN-CONTAINING PROTEIN 2 process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;autophagy#GO:0006914;cellular process#GO:0009987;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000008616.3|UniProtKB=G3QZV3 G3QZV3 QPCT PTHR12283:SF5 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;acyltransferase activity#GO:0016746;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004759.3|UniProtKB=G3QQ04 G3QQ04 RRAS2 PTHR24070:SF396 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN R-RAS2 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280 GORGO|Ensembl=ENSGGOG00000012987.3|UniProtKB=G3RB36 G3RB36 THBS1 PTHR10199:SF78 THROMBOSPONDIN THROMBOSPONDIN-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 regulation of vasculature development#GO:1901342;negative regulation of cellular process#GO:0048523;regulation of angiogenesis#GO:0045765;negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cell population proliferation#GO:0042127;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of cell population proliferation#GO:0008285;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 p53 pathway#P00059>TSP1#G01566 GORGO|Ensembl=ENSGGOG00000012835.3|UniProtKB=G3RAN9 G3RAN9 ZNF707 PTHR24399:SF95 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER PROTEIN 3 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000002415.3|UniProtKB=G3QJ05 G3QJ05 RBM25 PTHR18806:SF4 RBM25 PROTEIN RNA-BINDING PROTEIN 25 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889 GORGO|Ensembl=ENSGGOG00000039733.1|UniProtKB=A0A2I2ZC64 A0A2I2ZC64 CRCP PTHR15561:SF0 CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016080.3|UniProtKB=A0A2I2Y5T6 A0A2I2Y5T6 UBXN2B PTHR23333:SF14 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 2B protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 positive regulation of cell cycle#GO:0045787;proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;establishment of organelle localization#GO:0051656;regulation of cell cycle#GO:0051726;cellular component organization#GO:0016043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cellular localization#GO:0051641;spindle localization#GO:0051653;establishment or maintenance of cell polarity#GO:0007163;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;establishment of spindle localization#GO:0051293;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;primary metabolic process#GO:0044238;cell cycle#GO:0007049;modification-dependent protein catabolic process#GO:0019941;establishment of cell polarity#GO:0030010;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;organelle localization#GO:0051640 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000016241.3|UniProtKB=G3RJH5 G3RJH5 PTPRD PTHR19134:SF430 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE DELTA phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;synapse organization#GO:0050808;cell communication#GO:0007154;anatomical structure development#GO:0048856;synaptic membrane adhesion#GO:0099560;system development#GO:0048731;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;signaling#GO:0023052;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002994.3|UniProtKB=G3QKH2 G3QKH2 PTHR11686:SF56 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 1 PROENZYME-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;sulfur compound catabolic process#GO:0044273;modified amino acid metabolic process#GO:0006575;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;catabolic process#GO:0009056;glutathione metabolic process#GO:0006749;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;peptide metabolic process#GO:0006518 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000014581.2|UniProtKB=G3RF57 G3RF57 NCBP2L PTHR18847:SF5 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2-LIKE RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;RNA transport#GO:0050658;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;mRNA transport#GO:0051028;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA splicing, via transesterification reactions#GO:0000375;nucleocytoplasmic transport#GO:0006913;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nitrogen compound transport#GO:0071705;nucleobase-containing compound catabolic process#GO:0034655;macromolecule localization#GO:0033036;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;establishment of localization#GO:0051234;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000028361.2|UniProtKB=G3S376 G3S376 LUM PTHR45712:SF6 AGAP008170-PA LUMICAN collagen binding#GO:0005518;binding#GO:0005488;protein-containing complex binding#GO:0044877 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000011520.3|UniProtKB=G3R7A1 G3R7A1 GUCA2B PTHR11318:SF4 GUANYLIN FAMILY MEMBER GUANYLATE CYCLASE ACTIVATOR 2B enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000042300.1|UniProtKB=A0A2I2YQC5 A0A2I2YQC5 OMD PTHR45712:SF3 AGAP008170-PA OSTEOMODULIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002326.3|UniProtKB=A0A2I2Y8T8 A0A2I2Y8T8 RPL3 PTHR11363:SF4 60S RIBOSOMAL PROTEIN L3-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL3 nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000015984.3|UniProtKB=G3RIT6 G3RIT6 NT5DC2 PTHR12103:SF14 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 2 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000040280.1|UniProtKB=G3QN92 G3QN92 ITGAM PTHR23220:SF130 INTEGRIN ALPHA INTEGRIN ALPHA-M molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 integrin complex#GO:0008305;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 GORGO|Ensembl=ENSGGOG00000014355.3|UniProtKB=G3REL3 G3REL3 COQ6 PTHR43876:SF7 UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000004161.3|UniProtKB=A0A2I2YFY9 A0A2I2YFY9 LIN54 PTHR12446:SF36 TESMIN/TSO1-RELATED PROTEIN LIN-54 HOMOLOG regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000013528.3|UniProtKB=G3RCH6 G3RCH6 DSC1 PTHR24025:SF8 DESMOGLEIN FAMILY MEMBER DESMOCOLLIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000025033.2|UniProtKB=A0A2I2YNW4 A0A2I2YNW4 PTHR11158:SF31 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014 macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;localization#GO:0051179;establishment of localization#GO:0051234 mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000037070.1|UniProtKB=A0A2I2YAV8 A0A2I2YAV8 PTHR46289:SF16 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE GORGO|Ensembl=ENSGGOG00000016198.3|UniProtKB=G3RJB4 G3RJB4 PTHR19860:SF35 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 12-LIKE PROTEIN 1 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 GORGO|Ensembl=ENSGGOG00000001624.3|UniProtKB=G3QGY3 G3QGY3 OR10R2 PTHR26453:SF601 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003167.3|UniProtKB=G3QKY0 G3QKY0 SLBP PTHR17408:SF7 HISTONE RNA HAIRPIN-BINDING PROTEIN HISTONE RNA HAIRPIN-BINDING PROTEIN mRNA binding#GO:0003729;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;localization#GO:0051179;nucleic acid transport#GO:0050657;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;transport#GO:0006810;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;establishment of localization#GO:0051234;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;mRNA processing#GO:0006397;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015611.3|UniProtKB=G3RHV5 G3RHV5 TRPV6 PTHR10582:SF25 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 6 monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000004081.3|UniProtKB=G3QN94 G3QN94 DNAJC27 PTHR24073:SF269 DRAB5-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 27 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 GORGO|Ensembl=ENSGGOG00000003044.3|UniProtKB=G3QKL8 G3QKL8 LAMP1 PTHR11506:SF27 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000024243.2|UniProtKB=G3RXU7 G3RXU7 MAP3K7 PTHR46716:SF1 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;positive regulation of response to stimulus#GO:0048584;JNK cascade#GO:0007254;immune response#GO:0006955;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;TGF-beta signaling pathway#P00052>TAK#P01285;Interleukin signaling pathway#P00036>MEK#P00984;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Gonadotropin-releasing hormone receptor pathway#P06664>TAK1#P06799;p38 MAPK pathway#P05918>TAK1#P06037;Toll receptor signaling pathway#P00054>TAK1#P01370 GORGO|Ensembl=ENSGGOG00000027291.2|UniProtKB=A4K2R6 A4K2R6 PI3 PTHR19441:SF30 WAP four-disulfide core domain protein ELAFIN endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to other organism#GO:0051707;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000008139.3|UniProtKB=G3QYL8 G3QYL8 OAS3 PTHR11258:SF4 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;adenylyltransferase activity#GO:0070566;double-stranded RNA binding#GO:0003725;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;response to peptide#GO:1901652;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;defense response to other organism#GO:0098542;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;antiviral innate immune response#GO:0140374;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;response to virus#GO:0009615;immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000022902.2|UniProtKB=G3SII1 G3SII1 FCHO2 PTHR23065:SF8 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 F-BAR DOMAIN ONLY PROTEIN 2 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;cellular component assembly#GO:0022607;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;clathrin-dependent endocytosis#GO:0072583;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;endocytosis#GO:0006897;cellular localization#GO:0051641;localization#GO:0051179 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated vesicle#GO:0030136;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000011321.3|UniProtKB=G3R6R8 G3R6R8 SYNC PTHR47147:SF1 SYNCOILIN SYNCOILIN intermediate filament-based process#GO:0045103;cellular process#GO:0009987 I band#GO:0031674;neuromuscular junction#GO:0031594;membraneless organelle#GO:0043228;sarcolemma#GO:0042383;sarcomere#GO:0030017;cell junction#GO:0030054;membrane#GO:0016020;cytosol#GO:0005829;Z disc#GO:0030018;cell periphery#GO:0071944;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000002920.3|UniProtKB=G3QKA1 G3QKA1 ARID3C PTHR15348:SF2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3C DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000009746.3|UniProtKB=G3R2R2 G3R2R2 MANBA PTHR43730:SF1 BETA-MANNOSIDASE BETA-MANNOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000043527.1|UniProtKB=A0A2I2ZV74 A0A2I2ZV74 MCHR1 PTHR24229:SF91 NEUROPEPTIDES RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000005692.3|UniProtKB=G3QSD8 G3QSD8 MRPS24 PTHR21244:SF1 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN US3M ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000015869.3|UniProtKB=G3RIH2 G3RIH2 IL18 PTHR10078:SF35 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-18 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;biological regulation#GO:0065007;response to other organism#GO:0051707;immune response#GO:0006955;response to external stimulus#GO:0009605;defense response#GO:0006952;cellular response to molecule of bacterial origin#GO:0071219;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;inflammatory response#GO:0006954;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;interleukin superfamily#PC00128;cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870;Toll receptor signaling pathway#P00054>Gene trancription#G01550;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>INFgamma#P00878;Interleukin signaling pathway#P00036>Interleukin#P00970 GORGO|Ensembl=ENSGGOG00000010187.3|UniProtKB=G3R3W0 G3R3W0 SIRT1 PTHR11085:SF9 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1 histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;transcription corepressor activity#GO:0003714;transferase activity#GO:0016740;deacylase activity#GO:0160215;transcription coregulator activity#GO:0003712;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;transcription regulator activity#GO:0140110;acyltransferase activity#GO:0016746;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;constitutive heterochromatin formation#GO:0140719;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular response to stress#GO:0033554;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;heterochromatin formation#GO:0031507;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;nucleus#GO:0005634;chromatin#GO:0000785;organelle inner membrane#GO:0019866;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637;organelle lumen#GO:0043233;chromosome#GO:0005694;organelle envelope#GO:0031967;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 p53 pathway#P00059>SIRT-1#P04632 GORGO|Ensembl=ENSGGOG00000001882.3|UniProtKB=G3QHM1 G3QHM1 POLR1E PTHR14440:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transcription by RNA polymerase I#GO:0006360;DNA-templated transcription elongation#GO:0006354;transcription initiation at RNA polymerase I promoter#GO:0006361;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880 DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000041000.1|UniProtKB=A0A2I2ZSX2 A0A2I2ZSX2 LRRTM2 PTHR24373:SF268 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016743.3|UniProtKB=G3RKQ6 G3RKQ6 ZNF629 PTHR23226:SF333 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 629 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009531.3|UniProtKB=G3RY85 G3RY85 CP PTHR11709:SF226 MULTI-COPPER OXIDASE CERULOPLASMIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000022784.2|UniProtKB=G3S128 G3S128 CDCA2 PTHR21603:SF16 ANTIGEN KI-67-LIKE PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 2 molecular condensate scaffold activity#GO:0140693;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 sexual reproduction#GO:0019953;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cell cycle#GO:0007049;reproductive process#GO:0022414;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793 GORGO|Ensembl=ENSGGOG00000014119.3|UniProtKB=G3RE09 G3RE09 COL8A1 PTHR24023:SF903 COLLAGEN ALPHA COLLAGEN ALPHA-1(VIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000012967.3|UniProtKB=G3SA31 G3SA31 ADSSL1 PTHR11846:SF2 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 1 ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;ligase#PC00142 De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890;Wnt signaling pathway#P00057>NFAT Target Genes#G01559 GORGO|Ensembl=ENSGGOG00000003144.3|UniProtKB=G3QKV8 G3QKV8 ACP6 PTHR11567:SF202 ACID PHOSPHATASE-RELATED LYSOPHOSPHATIDIC ACID PHOSPHATASE TYPE 6 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000013606.3|UniProtKB=G3RNG8 G3RNG8 KAT8 PTHR10615:SF82 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT8 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 NSL complex#GO:0044545;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010899.3|UniProtKB=A0A2I2Z9K2 A0A2I2Z9K2 TUBG2 PTHR11588:SF79 TUBULIN TUBULIN GAMMA-2 CHAIN structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001 mitotic sister chromatid segregation#GO:0000070;microtubule polymerization or depolymerization#GO:0031109;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule polymerization#GO:0046785;chromosome organization#GO:0051276;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;sexual reproduction#GO:0019953;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;mitotic spindle organization#GO:0007052;microtubule nucleation#GO:0007020;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;nuclear division#GO:0000280 protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 tubulin#PC00228;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000041024.1|UniProtKB=A0A2I2YKE9 A0A2I2YKE9 PTHR11249:SF3 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR BETA protein-containing complex binding#GO:0044877;binding#GO:0005488 regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;actin filament-based process#GO:0030029;negative regulation of cytoskeleton organization#GO:0051494;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000012681.3|UniProtKB=G3RAB0 G3RAB0 PTHR10379:SF6 MTG8 ETO EIGHT TWENTY ONE PROTEIN TRANSCRIPTIONAL COREPRESSOR CBFA2T3 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000025933.2|UniProtKB=A0A2I2YQT8 A0A2I2YQT8 BCAS4 PTHR16230:SF5 CAPPUCCINO BREAST CARCINOMA-AMPLIFIED SEQUENCE 4 pigmentation#GO:0043473;melanosome organization#GO:0032438;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular pigmentation#GO:0033059 protein-containing complex#GO:0032991;BLOC-1 complex#GO:0031083;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000004247.3|UniProtKB=G3QNP5 G3QNP5 NAA20 PTHR45910:SF1 N-ALPHA-ACETYLTRANSFERASE 20 N-ALPHA-ACETYLTRANSFERASE 20 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein N-acyltransferase activity#GO:0140186 regulation of actin filament-based process#GO:0032970;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007 protein acetyltransferase complex#GO:0031248;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000006347.3|UniProtKB=G3QU17 G3QU17 SCGB2A2 PTHR14037:SF7 MAMMAGLOBIN-RELATED MAMMAGLOBIN-A response to steroid hormone#GO:0048545;cellular response to chemical stimulus#GO:0070887;intracellular signal transduction#GO:0035556;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to steroid hormone stimulus#GO:0071383;cellular process#GO:0009987;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;nuclear receptor-mediated signaling pathway#GO:0141193;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000041116.1|UniProtKB=A0A2I2Y453 A0A2I2Y453 FOXN3 PTHR13962:SF20 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N3 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000040020.1|UniProtKB=A0A2I2Z6D1 A0A2I2Z6D1 PTHR13422:SF16 SIN3-HDAC COMPLEX-ASSOCIATED FACTOR FAM60A regulation of locomotion#GO:0040012;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000003353.3|UniProtKB=G3QLE8 G3QLE8 PTHR15976:SF14 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000014992.3|UniProtKB=G3RG88 G3RG88 DLX4 PTHR24327:SF21 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-4 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;skeletal system development#GO:0001501;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000006963.3|UniProtKB=G3QVN3 G3QVN3 WDR31 PTHR19869:SF1 SPERMATID WD-REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 31 GORGO|Ensembl=ENSGGOG00000043295.1|UniProtKB=A0A2I2YLX0 A0A2I2YLX0 LOC101151822 PTHR13337:SF9 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT heme binding#GO:0020037;binding#GO:0005488;small molecule binding#GO:0036094;tetrapyrrole binding#GO:0046906 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152 catalytic complex#GO:1902494;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000008590.3|UniProtKB=G3QZT0 G3QZT0 NUFIP2 PTHR28333:SF2 NUCLEAR FRAGILE X MENTAL RETARDATION-INTERACTING PROTEIN 2 FMR1-INTERACTING PROTEIN NUFIP2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle lumen#GO:0043233;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000000370.3|UniProtKB=G3QDN9 G3QDN9 TTC5 PTHR26312:SF87 TETRATRICOPEPTIDE REPEAT PROTEIN 5 TETRATRICOPEPTIDE REPEAT PROTEIN 5 GORGO|Ensembl=ENSGGOG00000009341.2|UniProtKB=A0A2I2YDD1 A0A2I2YDD1 LOC101135299 PTHR11937:SF417 ACTIN ACTIN-RELATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;structural molecule activity#GO:0005198;actin binding#GO:0003779;actin filament binding#GO:0051015;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000014644.3|UniProtKB=G3RFB9 G3RFB9 DRD3 PTHR24248:SF154 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(3) DOPAMINE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;G protein-coupled receptor signaling pathway#GO:0007186;response to nitrogen compound#GO:1901698;adrenergic receptor signaling pathway#GO:0071875;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;cellular response to nitrogen compound#GO:1901699;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of cellular process#GO:0048523 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603 GORGO|Ensembl=ENSGGOG00000022940.2|UniProtKB=G3RWT9 G3RWT9 APIP PTHR10640:SF7 METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;sulfur compound metabolic process#GO:0006790;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;purine-containing compound metabolic process#GO:0072521;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007103.3|UniProtKB=G3QW07 G3QW07 RNF13 PTHR22765:SF34 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF13 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cellular process#GO:0009987;biological regulation#GO:0065007;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011206.3|UniProtKB=G3R6H2 G3R6H2 ZNF846 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000027940.2|UniProtKB=G3RPH8 G3RPH8 NEUROD1 PTHR19290:SF88 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cell development#GO:0048468;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000008287.3|UniProtKB=A0A2I2YG62 A0A2I2YG62 GSDMB PTHR16399:SF20 GASDERMIN GASDERMIN-B phosphatidylserine binding#GO:0001786;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 inflammatory response#GO:0006954;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000028457.2|UniProtKB=A0A2I2ZVQ5 A0A2I2ZVQ5 PTHR12895:SF9 DYMECLIN DYMECLIN cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Golgi organization#GO:0007030 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000024008.2|UniProtKB=G3S446 G3S446 TMLHE PTHR10696:SF51 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;carnitine metabolic process#GO:0009437 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000004337.3|UniProtKB=A0A2I2ZHP1 A0A2I2ZHP1 HORMAD1 PTHR48225:SF1 HORMA DOMAIN-CONTAINING PROTEIN 1 HORMA DOMAIN-CONTAINING PROTEIN 1 negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of reproductive process#GO:2000241;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of cell cycle#GO:0051726;nuclear division#GO:0000280;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component assembly#GO:0022607;cell cycle checkpoint signaling#GO:0000075;synaptonemal complex assembly#GO:0007130;homologous chromosome pairing at meiosis#GO:0007129;regulation of cell cycle process#GO:0010564;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;negative regulation of cell cycle#GO:0045786 condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;synaptonemal structure#GO:0099086;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000039563.1|UniProtKB=A0A2I2Y5M6 A0A2I2Y5M6 STAC2 PTHR15135:SF5 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN 2 transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 muscle contraction#GO:0006936;system process#GO:0003008;regulation of localization#GO:0032879;regulation of protein localization to membrane#GO:1905475;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuromuscular process#GO:0050905;nervous system process#GO:0050877;regulation of protein localization#GO:0032880;muscle system process#GO:0003012;regulation of biological process#GO:0050789;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794 cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003273.3|UniProtKB=G3QL72 G3QL72 LIPN PTHR11005:SF16 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER N hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 lipase#PC00143;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000038806.1|UniProtKB=A0A2I2ZED6 A0A2I2ZED6 CD300E PTHR11860:SF89 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of innate immune response#GO:0045088;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of response to biotic stimulus#GO:0002831;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000006196.3|UniProtKB=G3RSB2 G3RSB2 PCNX1 PTHR12372:SF2 PECANEX PECANEX-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000005440.3|UniProtKB=G3QRR2 G3QRR2 ZNF623 PTHR24393:SF113 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 623 transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000015441.3|UniProtKB=G3RHE6 G3RHE6 ACOX2 PTHR10909:SF344 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 2 nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;lipid binding#GO:0008289;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;organic acid binding#GO:0043177;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;very long-chain fatty acid metabolic process#GO:0000038;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000001408.3|UniProtKB=G3QGD6 G3QGD6 KLK1 PTHR24271:SF47 KALLIKREIN-RELATED KALLIKREIN-1 serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 circulatory system process#GO:0003013;proteolysis#GO:0006508;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;zymogen activation#GO:0031638;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;system process#GO:0003008;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;gene expression#GO:0010467;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;blood circulation#GO:0008015;biological regulation#GO:0065007;biosynthetic process#GO:0009058 extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000024411.2|UniProtKB=G3SFQ1 G3SFQ1 GHSR PTHR24243:SF7 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000005199.3|UniProtKB=G3QR58 G3QR58 ALG12 PTHR22760:SF1 GLYCOSYLTRANSFERASE DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000027073.2|UniProtKB=G3RXJ7 G3RXJ7 PTHR10026:SF70 CYCLIN CYCLIN-Q molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000004156.3|UniProtKB=A0A2I2Z3R8 A0A2I2Z3R8 PTHR23226:SF397 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 84 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003342.3|UniProtKB=G3SB52 G3SB52 PTHR19960:SF28 TEKTIN SUBFAMILY NOT NAMED cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000025780.2|UniProtKB=G3SJ56 G3SJ56 LOC101151087 PTHR24103:SF666 E3 UBIQUITIN-PROTEIN LIGASE TRIM RET FINGER PROTEIN-LIKE 4A-RELATED acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;immune system process#GO:0002376;biological regulation#GO:0065007;response to other organism#GO:0051707;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Gene=HTR1B|UniProtKB=Q9N2B7 Q9N2B7 HTR1B PTHR24247:SF16 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1B transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000002811.3|UniProtKB=G3QK07 G3QK07 PSAPL1 PTHR11480:SF39 SAPOSIN-RELATED PROACTIVATOR POLYPEPTIDE-LIKE 1 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of lipid metabolic process#GO:0019216;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010441.3|UniProtKB=G3RYQ1 G3RYQ1 ITPRIPL1 PTHR10656:SF40 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN-LIKE 1 nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular anatomical structure#GO:0110165;membrane#GO:0016020 nucleotidyltransferase#PC00174;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000022393.2|UniProtKB=G3RWV9 G3RWV9 PTHR23203:SF20 PROLINE-RICH PROTEIN BASIC SALIVARY PROLINE-RICH PROTEIN 1-RELATED antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000008833.3|UniProtKB=G3R0F0 G3R0F0 SPMAP1 PTHR34221:SF2 HYPOTHETICAL PROTEIN LOC691189 SPERM MICROTUBULE ASSOCIATED PROTEIN 1 GORGO|Ensembl=ENSGGOG00000012016.3|UniProtKB=G3QNS8 G3QNS8 KYAT3 PTHR43807:SF6 FI04487P KYNURENINE--OXOGLUTARATE TRANSAMINASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000011663.3|UniProtKB=A0A2I2ZXW3 A0A2I2ZXW3 PPP1CC PTHR11668:SF204 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cellular process#GO:0009987;regulation of circadian rhythm#GO:0042752;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602;Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969 GORGO|Ensembl=ENSGGOG00000010457.3|UniProtKB=A0A2I2YHR3 A0A2I2YHR3 SORBS1 PTHR14167:SF64 SH3 DOMAIN-CONTAINING SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 organelle organization#GO:0006996;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;cell junction#GO:0030054;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025486.2|UniProtKB=G3SI02 G3SI02 PTHR23267:SF471 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-16 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000013355.3|UniProtKB=A0A2I2YKF8 A0A2I2YKF8 SMARCD1 PTHR13844:SF1 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000025872.2|UniProtKB=G3RBF6 G3RBF6 PTHR24381:SF400 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 829 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007831.3|UniProtKB=G3QXU8 G3QXU8 NGEF PTHR12845:SF8 GUANINE NUCLEOTIDE EXCHANGE FACTOR EPHEXIN-1 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000007452.3|UniProtKB=G3QWX4 G3QWX4 ACE2 PTHR10514:SF24 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME 2 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 metabolic process#GO:0008152;system process#GO:0003008;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;biological regulation#GO:0065007;biosynthetic process#GO:0009058;hormone metabolic process#GO:0042445;blood circulation#GO:0008015;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;proteolysis#GO:0006508;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000007788.3|UniProtKB=G3QXR1 G3QXR1 HBP1 PTHR15499:SF3 HMG BOX-CONTAINING PROTEIN 1 HMG BOX-CONTAINING PROTEIN 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000012497.3|UniProtKB=G3R9U1 G3R9U1 BACH2 PTHR46105:SF8 AGAP004733-PA TRANSCRIPTION REGULATOR PROTEIN BACH2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000044102.1|UniProtKB=A0A2I2Z467 A0A2I2Z467 LOC101142721 PTHR32344:SF1 U1-TYPE DOMAIN-CONTAINING PROTEIN U1-TYPE DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012458.3|UniProtKB=G3R9Q8 G3R9Q8 CLEC14A PTHR14789:SF5 CHONDROLECTIN VARIANT CHODLFDELTAE. C-TYPE LECTIN DOMAIN FAMILY 14 MEMBER A binding#GO:0005488;extracellular matrix binding#GO:0050840;protein binding#GO:0005515 cell motility#GO:0048870;cell migration#GO:0016477;cellular process#GO:0009987 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 GORGO|Ensembl=ENSGGOG00000024190.2|UniProtKB=A0A2I2ZH59 A0A2I2ZH59 RAB28 PTHR24073:SF572 DRAB5-RELATED RAS-RELATED PROTEIN RAB-28 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000007694.3|UniProtKB=G3QXI1 G3QXI1 GPR83 PTHR24238:SF82 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 83 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008474.3|UniProtKB=G3RZ80 G3RZ80 CCDC77 PTHR22091:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 77 COILED-COIL DOMAIN-CONTAINING PROTEIN 77 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000010787.3|UniProtKB=G3R5E2 G3R5E2 FEV PTHR11849:SF203 ETS PROTEIN FEV DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000009622.3|UniProtKB=Q645Z1 Q645Z1 TAS2R5 PTHR11394:SF8 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 5 taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000033.3|UniProtKB=G3QCT5 G3QCT5 EBF1 PTHR10747:SF26 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;P53-like transcription factor#PC00253 GORGO|Ensembl=ENSGGOG00000028388.2|UniProtKB=A0A2I2YKG2 A0A2I2YKG2 PTHR22812:SF144 CHROMOBOX PROTEIN CHROMO DOMAIN-CONTAINING PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular component assembly#GO:0022607 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006481.3|UniProtKB=A0A2I2ZE85 A0A2I2ZE85 PTHR10502:SF189 ANNEXIN ANNEXIN lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phospholipid binding#GO:0005543 regulation of proteolysis#GO:0030162;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein metabolic process#GO:0051247;cell adhesion#GO:0007155;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000010124.3|UniProtKB=G3R3Q1 G3R3Q1 PMM2 PTHR10466:SF2 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE 2 intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 protein metabolic process#GO:0019538;hexose metabolic process#GO:0019318;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 mutase#PC00160;isomerase#PC00135;metabolite interconversion enzyme#PC00262 Mannose metabolism#P02752>P-Mannose mutase#P03019 GORGO|Ensembl=ENSGGOG00000009471.3|UniProtKB=G3R215 G3R215 CHRNA10 PTHR18945:SF889 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-10 ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023 cellular process#GO:0009987;synaptic signaling#GO:0099536;detection of stimulus involved in sensory perception#GO:0050906;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;signaling#GO:0023052;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;nervous system process#GO:0050877;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;synaptic transmission, cholinergic#GO:0007271;response to mechanical stimulus#GO:0009612;detection of stimulus#GO:0051606;system process#GO:0003008;response to external stimulus#GO:0009605;establishment of localization#GO:0051234;transport#GO:0006810;detection of mechanical stimulus#GO:0050982;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;trans-synaptic signaling#GO:0099537 organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane protein complex#GO:0098796;postsynapse#GO:0098794;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 GORGO|Ensembl=ENSGGOG00000003781.3|UniProtKB=A0A2I2ZFQ4 A0A2I2ZFQ4 NF2 PTHR23281:SF23 MERLIN/MOESIN/EZRIN/RADIXIN MERLIN cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;integrin binding#GO:0005178;signaling receptor binding#GO:0005102;binding#GO:0005488;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;regulation of multicellular organismal development#GO:2000026;regulation of cell shape#GO:0008360;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of hippo signaling#GO:0035330;regulation of cellular component organization#GO:0051128;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of multicellular organismal process#GO:0051239;regulation of cell population proliferation#GO:0042127;regulation of nervous system development#GO:0051960;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;negative regulation of cell population proliferation#GO:0008285;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cytoskeleton#GO:0005856;apical part of cell#GO:0045177;cell junction#GO:0030054;membraneless organelle#GO:0043228;adherens junction#GO:0005912;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;filopodium#GO:0030175;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000041341.1|UniProtKB=A0A2I2ZT18 A0A2I2ZT18 SLAMF9 PTHR12080:SF18 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;biological regulation#GO:0065007;T cell activation#GO:0042110;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;cell activation#GO:0001775;cell communication#GO:0007154 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000022567.2|UniProtKB=G3QT24 G3QT24 LOC101140367 PTHR12015:SF103 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 4-LIKE signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125 response to peptide#GO:1901652;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell motility#GO:2000147;cell surface receptor signaling pathway#GO:0007166;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;taxis#GO:0042330;response to cytokine#GO:0034097;response to chemical#GO:0042221;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;response to stress#GO:0006950;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;regulation of cell motility#GO:2000145;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cytokine-mediated signaling pathway#GO:0019221;response to external biotic stimulus#GO:0043207;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;cell migration#GO:0016477;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000015597.3|UniProtKB=G3RHT9 G3RHT9 SCIN PTHR11977:SF78 VILLIN SCINDERIN phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;phosphatidylinositol phosphate binding#GO:1901981;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289 regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell projection assembly#GO:0030031;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;regulation of actin filament length#GO:0030832;animal gross anatomical part developmental process#GO:0160108;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;central nervous system development#GO:0007417;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of actin filament polymerization#GO:0030833;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;supramolecular fiber organization#GO:0097435;system development#GO:0048731;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein-containing complex disassembly#GO:0043242;anatomical structure development#GO:0048856;negative regulation of cytoskeleton organization#GO:0051494;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of actin filament depolymerization#GO:0030834;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 GORGO|Ensembl=ENSGGOG00000043301.1|UniProtKB=A0A2I2Z747 A0A2I2Z747 PTHR14360:SF13 PROTEIN FMP32, MITOCHONDRIAL COILED-COIL DOMAIN CONTAINING 90B intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000013796.3|UniProtKB=A0A2I2Z0C8 A0A2I2Z0C8 WDR90 PTHR13720:SF24 WD-40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 90 organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000028494.2|UniProtKB=G3RYS4 G3RYS4 PTHR10165:SF14 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 3 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 signaling#GO:0023052;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cell communication#GO:0007154;dephosphorylation#GO:0016311;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000006067.3|UniProtKB=G3QTC0 G3QTC0 LRRC8B PTHR45752:SF40 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8B monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 aspartate transmembrane transport#GO:0015810;nitrogen compound transport#GO:0071705;biological regulation#GO:0065007;dicarboxylic acid transport#GO:0006835;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;establishment of localization#GO:0051234;cellular response to stimulus#GO:0051716;carbohydrate derivative transport#GO:1901264;monoatomic anion transport#GO:0006820;carboxylic acid transmembrane transport#GO:1905039;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;signal transduction#GO:0007165;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;amino acid transport#GO:0006865;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;import into cell#GO:0098657;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085 intracellular anatomical structure#GO:0005622;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008826.3|UniProtKB=G3R0F4 G3R0F4 ZNF236 PTHR24396:SF21 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 236 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000037675.1|UniProtKB=A0A2I2ZEF0 A0A2I2ZEF0 PTHR23411:SF38 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823 immune effector process#GO:0002252;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;antibacterial humoral response#GO:0019731;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;defense response to bacterium#GO:0042742;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;defense response#GO:0006952;response to external stimulus#GO:0009605;complement activation#GO:0006956;immune response#GO:0006955;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000013299.3|UniProtKB=A0A2I2YZT0 A0A2I2YZT0 STXBP1 PTHR11679:SF35 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 1 binding#GO:0005488;SNARE binding#GO:0000149;syntaxin binding#GO:0019905;protein binding#GO:0005515 establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;synaptic signaling#GO:0099536;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;intracellular protein transport#GO:0006886;regulated exocytosis#GO:0045055;signaling#GO:0023052;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;protein transport#GO:0015031;secretion by cell#GO:0032940;cellular localization#GO:0051641;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;vesicle localization#GO:0051648;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;calcium-ion regulated exocytosis#GO:0017156;intracellular transport#GO:0046907;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;signal release#GO:0023061 plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Munc18#P05770 GORGO|Ensembl=ENSGGOG00000008827.3|UniProtKB=G3R0E5 G3R0E5 MFSD4B PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 2 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016651.3|UniProtKB=G3RKI1 G3RKI1 HUNK PTHR24346:SF80 MAP/MICROTUBULE AFFINITY-REGULATING KINASE HORMONALLY UP-REGULATED NEU TUMOR-ASSOCIATED KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000043023.1|UniProtKB=A0A2I2YPQ6 A0A2I2YPQ6 PTHR23147:SF233 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 4 circadian rhythm#GO:0007623;rhythmic process#GO:0048511 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000014990.3|UniProtKB=G3RG89 G3RG89 LCN2 PTHR11430:SF13 LIPOCALIN NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000009834.3|UniProtKB=G3R2Z3 G3R2Z3 TMEM183A PTHR20988:SF2 TRANSMEMBRANE PROTEIN 183A-RELATED TRANSMEMBRANE PROTEIN 183A-RELATED transferase complex#GO:1990234;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000017092.3|UniProtKB=G3RLM6 G3RLM6 NKX2-5 PTHR24340:SF28 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.5 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000037480.1|UniProtKB=A0A2I2YC01 A0A2I2YC01 FLRT2 PTHR45712:SF16 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000000934.3|UniProtKB=G3QF57 G3QF57 IDI1 PTHR10885:SF5 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE 1 catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;metabolic process#GO:0008152;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 isomerase#PC00135 Cholesterol biosynthesis#P00014>Isopentenyl diphosphate delta-isomerase#P00495 GORGO|Ensembl=ENSGGOG00000039748.1|UniProtKB=A0A2I2ZGX9 A0A2I2ZGX9 TMEM47 PTHR14399:SF3 P53-INDUCED PROTEIN RELATED TRANSMEMBRANE PROTEIN 47 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 GORGO|Ensembl=ENSGGOG00000009265.3|UniProtKB=A0A2I2ZKU4 A0A2I2ZKU4 TPRX1 PTHR45793:SF12 HOMEOBOX PROTEIN TETRAPEPTIDE REPEAT HOMEOBOX 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000003859.3|UniProtKB=G3S4T4 G3S4T4 FCGR2B PTHR11481:SF97 IMMUNOGLOBULIN FC RECEPTOR LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR II-B-RELATED immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;protein-containing complex binding#GO:0044877;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of localization#GO:0032879;regulation of transport#GO:0051049;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;regulation of endocytosis#GO:0030100;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;response to stress#GO:0006950;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of cellular component organization#GO:0051130;immune system process#GO:0002376;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;leukocyte mediated cytotoxicity#GO:0001909;defense response#GO:0006952;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;cell killing#GO:0001906;adaptive immune response#GO:0002250;biological regulation#GO:0065007;positive regulation of endocytosis#GO:0045807;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;acute inflammatory response#GO:0002526;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000015878.3|UniProtKB=G3RII0 G3RII0 LOC101146821 PTHR24242:SF356 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016634.3|UniProtKB=A0A2I2Z1A5 A0A2I2Z1A5 WDR81 PTHR44662:SF1 WD REPEAT-CONTAINING PROTEIN 81 WD REPEAT-CONTAINING PROTEIN 81 enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 metabolic process#GO:0008152;cellular process#GO:0009987;autophagy#GO:0006914;catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000003239.3|UniProtKB=G3QL44 G3QL44 KRBA1 PTHR22740:SF3 PROTEIN KRBA1 KRAB DOMAIN-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000016331.3|UniProtKB=G3RJN8 G3RJN8 CRYM PTHR13812:SF25 KETIMINE REDUCTASE MU-CRYSTALLIN KETIMINE REDUCTASE MU-CRYSTALLIN binding#GO:0005488;hormone binding#GO:0042562 regulation of biological quality#GO:0065008;metabolic process#GO:0008152;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;modified amino acid metabolic process#GO:0006575;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 reductase#PC00198;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000023095.2|UniProtKB=G3S299 G3S299 RPS7 PTHR11278:SF5 40S RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN ES7 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cytosolic small ribosomal subunit#GO:0022627;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small-subunit processome#GO:0032040;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012025.3|UniProtKB=G3R8L7 G3R8L7 ZNF213 PTHR23226:SF258 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 213 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005633.3|UniProtKB=G3QS86 G3QS86 PTHR28593:SF1 METEORIN-LIKE PROTEIN METEORIN-LIKE PROTEIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;multicellular organismal-level homeostasis#GO:0048871;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of fat cell differentiation#GO:0045600;positive regulation of developmental process#GO:0051094 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000014050.3|UniProtKB=G3RDU2 G3RDU2 FGB PTHR19143:SF332 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN BETA CHAIN gene expression#GO:0010467;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;homotypic cell-cell adhesion#GO:0034109;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to stress#GO:0006950;response to wounding#GO:0009611;cell-cell adhesion#GO:0098609;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;coagulation#GO:0050817;macromolecule metabolic process#GO:0043170;platelet activation#GO:0030168;blood coagulation#GO:0007596;metabolic process#GO:0008152;platelet aggregation#GO:0070527;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;hemostasis#GO:0007599;protein metabolic process#GO:0019538;cell-substrate adhesion#GO:0031589;protein activation cascade#GO:0072376;regulation of biological quality#GO:0065008;wound healing#GO:0042060;cell activation#GO:0001775;blood coagulation, fibrin clot formation#GO:0072378;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443;Blood coagulation#P00011>Fibrinogen#P00406;Blood coagulation#P00011>Fibrin monomer#P00418 GORGO|Ensembl=ENSGGOG00000004049.3|UniProtKB=G3QN67 G3QN67 NARS2 PTHR22594:SF59 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINYL-TRNA SYNTHETASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000007731.3|UniProtKB=G3QXL7 G3QXL7 PTHR21549:SF1 MUTATED IN BLADDER CANCER 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 148 GORGO|Ensembl=ENSGGOG00000012070.3|UniProtKB=G3R8Q5 G3R8Q5 PTHR13338:SF5 UPF0240 PROTEIN NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 4 cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000043272.1|UniProtKB=G3QQD7 G3QQD7 LOC101149184 PTHR31283:SF4 EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER CANCER_TESTIS ANTIGEN 1 protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000014597.3|UniProtKB=G3RF79 G3RF79 BARD1 PTHR24171:SF8 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1 GORGO|Ensembl=ENSGGOG00000016139.3|UniProtKB=G3S7V7 G3S7V7 PROM1 PTHR22730:SF3 PROMININ PROM PROTEIN PROMININ-1 cell projection organization#GO:0030030;cell differentiation#GO:0030154;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;visual system development#GO:0150063;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;retina development in camera-type eye#GO:0060041;nervous system development#GO:0007399;camera-type eye morphogenesis#GO:0048593;sensory system development#GO:0048880;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;neurogenesis#GO:0022008;sensory organ development#GO:0007423;developmental process#GO:0032502;neuron differentiation#GO:0030182 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microvillus#GO:0005902;actin-based cell projection#GO:0098858;vesicle#GO:0031982;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;apical part of cell#GO:0045177;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000041754.1|UniProtKB=A0A2I2YR56 A0A2I2YR56 PTHR11849:SF288 ETS ETS DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000012992.3|UniProtKB=G3RB55 G3RB55 PIKFYVE PTHR46715:SF1 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;endocytosis#GO:0006897;regulation of reactive oxygen species metabolic process#GO:2000377;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;lysosome organization#GO:0007040;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;cellular pigmentation#GO:0033059;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;neutrophil migration#GO:1990266;glycerophospholipid metabolic process#GO:0006650;response to chemical#GO:0042221;taxis#GO:0042330;vesicle-mediated transport#GO:0016192;granulocyte migration#GO:0097530;melanosome organization#GO:0032438;neutrophil chemotaxis#GO:0030593;phagolysosome assembly#GO:0001845;metabolic process#GO:0008152;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;vesicle fusion#GO:0006906;phospholipid metabolic process#GO:0006644;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cell motility#GO:0048870;pigmentation#GO:0043473;chemotaxis#GO:0006935;organelle assembly#GO:0070925;vacuole organization#GO:0007033;cell chemotaxis#GO:0060326;localization#GO:0051179;membrane fusion#GO:0061025;organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;membrane organization#GO:0061024;cell migration#GO:0016477;transport#GO:0006810;lipid metabolic process#GO:0006629;lytic vacuole organization#GO:0080171;leukocyte migration#GO:0050900;phagocytosis#GO:0006909;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;phagocytic vesicle#GO:0045335;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000010553.3|UniProtKB=G3S010 G3S010 BSN PTHR14113:SF1 PICCOLO/BASSOON PROTEIN BASSOON structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;protein localization to cell junction#GO:1902414;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;protein localization to synapse#GO:0035418;intracellular protein localization#GO:0008104;developmental process#GO:0032502;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 axon#GO:0030424;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;GABA-ergic synapse#GO:0098982;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;presynaptic active zone#GO:0048786;neuron projection#GO:0043005;presynapse#GO:0098793;cell periphery#GO:0071944;glutamatergic synapse#GO:0098978;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000004847.3|UniProtKB=A0A2I2Y4Z3 A0A2I2Y4Z3 TPD52L1 PTHR19307:SF8 TUMOR PROTEIN D52 TUMOR PROTEIN D53 regulation of apoptotic signaling pathway#GO:2001233;mitotic cell cycle phase transition#GO:0044772;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;positive regulation of signal transduction#GO:0009967;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of JNK cascade#GO:0046328;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;cell cycle G2/M phase transition#GO:0044839;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014762.3|UniProtKB=G3RFN4 G3RFN4 TIGD3 PTHR19303:SF36 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000025330.2|UniProtKB=G3RUE6 G3RUE6 PTHR13248:SF6 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2 ELONGIN-B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of metabolic process#GO:0009892;protein catabolic process#GO:0030163;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;post-transcriptional gene silencing#GO:0016441;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Cul2-RING ubiquitin ligase complex#GO:0031462;intracellular organelle lumen#GO:0070013;cullin-RING ubiquitin ligase complex#GO:0031461;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000016775.3|UniProtKB=G3RKT2 G3RKT2 ZNF792 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000026070.2|UniProtKB=G3RNW6 G3RNW6 ZNF311 PTHR24377:SF273 IP01015P-RELATED ZINC FINGER PROTEIN 311 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012734.3|UniProtKB=G3RAF8 G3RAF8 TTC27 PTHR16193:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 27 TETRATRICOPEPTIDE REPEAT PROTEIN 27 GORGO|Ensembl=ENSGGOG00000036215.1|UniProtKB=A0A2I2ZBU7 A0A2I2ZBU7 PTHR38498:SF1 TRANSMEMBRANE PROTEIN 191B-RELATED TRANSMEMBRANE PROTEIN 191C GORGO|Ensembl=ENSGGOG00000012638.3|UniProtKB=G3RA66 G3RA66 APRT PTHR32315:SF3 ADENINE PHOSPHORIBOSYLTRANSFERASE ADENINE PHOSPHORIBOSYLTRANSFERASE pentosyltransferase activity#GO:0016763;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;cation binding#GO:0043169;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;glycosyltransferase activity#GO:0016757;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;organophosphate biosynthetic process#GO:0090407;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220 Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphoribosyl transferase#P02810 GORGO|Ensembl=ENSGGOG00000011113.3|UniProtKB=A0A2I2YN01 A0A2I2YN01 NSG1 PTHR28546:SF3 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;regulation of biological quality#GO:0065008;protein transport#GO:0015031;metabolic process#GO:0008152;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transport#GO:0006810;biological regulation#GO:0065007;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;vesicle#GO:0031982;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;endomembrane system#GO:0012505;glutamatergic synapse#GO:0098978;late endosome#GO:0005770;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 GORGO|Ensembl=ENSGGOG00000022349.2|UniProtKB=G3RUY6 G3RUY6 MYMX PTHR41686:SF1 MYOMIXER PROTEIN MYOMIXER cell differentiation#GO:0030154;muscle structure development#GO:0061061;myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;animal organ development#GO:0048513;striated muscle cell differentiation#GO:0051146;muscle organ development#GO:0007517;cell-cell fusion#GO:0140253;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 GORGO|Ensembl=ENSGGOG00000013307.3|UniProtKB=G3RV25 G3RV25 MIER2 PTHR10865:SF27 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 2 protein binding#GO:0005515;histone deacetylase binding#GO:0042826;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000010941.3|UniProtKB=G3RWW2 G3RWW2 TAP2 PTHR24221:SF237 ATP-BINDING CASSETTE SUB-FAMILY B ANTIGEN PEPTIDE TRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000007205.3|UniProtKB=G3QW97 G3QW97 CSTF1 PTHR44133:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000008023.3|UniProtKB=A0A2I2YQN9 A0A2I2YQN9 PREX1 PTHR22829:SF6 DEP DOMAIN PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 1 PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function activator activity#GO:0140677;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875 GORGO|Ensembl=ENSGGOG00000002924.3|UniProtKB=G3QKA2 G3QKA2 SIGMAR1 PTHR10868:SF4 SIGMA 1-TYPE OPIOID RECEPTOR-RELATED SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067;regulation of cellular response to stress#GO:0080135;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134 intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;neuron to neuron synapse#GO:0098984;endomembrane system#GO:0012505;postsynaptic specialization#GO:0099572;cell junction#GO:0030054;endoplasmic reticulum#GO:0005783 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016469.3|UniProtKB=G3RK15 G3RK15 LOC101149966 PTHR11559:SF441 CARBOXYLESTERASE LIVER CARBOXYLESTERASE 1-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 short-chain fatty acid catabolic process#GO:0019626;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000017089.3|UniProtKB=G3SB57 G3SB57 BRAF PTHR23257:SF731 SERINE-THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000026189.2|UniProtKB=G3RV70 G3RV70 ZNF549 PTHR24377:SF690 IP01015P-RELATED ZINC FINGER PROTEIN 549 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002308.3|UniProtKB=G3QIQ7 G3QIQ7 MAB21L3 PTHR10656:SF30 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 3 transferase#PC00220;nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000008961.3|UniProtKB=G3R0S2 G3R0S2 SEPTIN3 PTHR18884:SF62 SEPTIN NEURONAL-SPECIFIC SEPTIN-3 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;cellular process#GO:0009987;cell division#GO:0051301 intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000008782.3|UniProtKB=G3RQS9 G3RQS9 ZNF605 PTHR24381:SF455 ZINC FINGER PROTEIN RB-ASSOCIATED KRAB ZINC FINGER PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000023913.2|UniProtKB=G3SE39 G3SE39 TMEM106A PTHR28556:SF3 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106A macrophage activation#GO:0042116;multicellular organismal process#GO:0032501;myeloid leukocyte activation#GO:0002274;cellular process#GO:0009987;cell activation#GO:0001775;leukocyte activation#GO:0045321;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000037216.1|UniProtKB=A0A2I2ZTI5 A0A2I2ZTI5 PTHR18860:SF84 14-3-3 PROTEIN 14-3-3 DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000017040.3|UniProtKB=G3RLI2 G3RLI2 ANGEL1 PTHR12121:SF28 CARBON CATABOLITE REPRESSOR PROTEIN 4 RNA 2',3'-CYCLIC PHOSPHATASE ANGEL1 RNA nuclease activity#GO:0004540;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;phosphoric ester hydrolase activity#GO:0042578;mRNA 3'-UTR binding#GO:0003730;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;mRNA binding#GO:0003729;binding#GO:0005488;3'-5'-RNA exonuclease activity#GO:0000175 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA processing#GO:0006397;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;mitochondrial RNA processing#GO:0000963;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000013185.3|UniProtKB=G3RBK3 G3RBK3 LOC101123936 PTHR36462:SF1 CHROMOSOME 12 OPEN READING FRAME 71 CHROMOSOME 11 C12ORF71 HOMOLOG GORGO|Ensembl=ENSGGOG00000017046.3|UniProtKB=G3RLI9 G3RLI9 KIF19 PTHR46272:SF3 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G PROTEIN-COUPLED RECEPTOR 139-RELATED signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154 GORGO|Ensembl=ENSGGOG00000001423.3|UniProtKB=G3QGF1 G3QGF1 RASGEF1B PTHR23113:SF197 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1B guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000008395.3|UniProtKB=G3QZA3 G3QZA3 RAB3IP PTHR14430:SF2 RABIN3-RELATED RAB-3A-INTERACTING PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000014411.3|UniProtKB=G3RER1 G3RER1 PTHR16434:SF2 EWING'S TUMOR-ASSOCIATED ANTIGEN 1 ETAA1 EWING'S TUMOR-ASSOCIATED ANTIGEN 1 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;DNA-templated DNA replication#GO:0006261;regulation of cellular response to stress#GO:0080135;regulation of cell cycle phase transition#GO:1901987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of response to stress#GO:0080134;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;replication fork processing#GO:0031297 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000041634.1|UniProtKB=A0A2I2Y8S3 A0A2I2Y8S3 BTLA PTHR37996:SF1 B- AND T-LYMPHOCYTE ATTENUATOR B- AND T-LYMPHOCYTE ATTENUATOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of immune response#GO:0050776;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012382.3|UniProtKB=G3SDN9 G3SDN9 PTHR15566:SF6 POM121-LIKE POM121-LIKE PROTEIN 1-RELATED GORGO|Ensembl=ENSGGOG00000038214.1|UniProtKB=A0A2I2YTR2 A0A2I2YTR2 CERS6 PTHR12560:SF43 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 6 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;ceramide metabolic process#GO:0006672;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000036597.1|UniProtKB=A0A2I2ZGR0 A0A2I2ZGR0 RHOG PTHR24072:SF158 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOG pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515 locomotion#GO:0040011;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029;chemotaxis#GO:0006935;cortical cytoskeleton organization#GO:0030865;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cell migration#GO:0016477;response to external stimulus#GO:0009605;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;Rac protein signal transduction#GO:0016601;cellular response to chemical stimulus#GO:0070887;establishment or maintenance of cell polarity#GO:0007163;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;cytoskeleton organization#GO:0007010;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 G-protein#PC00020;small GTPase#PC00208 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Huntington disease#P00029>Rac#P00775;EGF receptor signaling pathway#P00018>Rac#P00564 GORGO|Ensembl=ENSGGOG00000012128.3|UniProtKB=G3SGN3 G3SGN3 LHFPL5 PTHR12489:SF18 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 5 PROTEIN system process#GO:0003008;response to external stimulus#GO:0009605;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of mechanical stimulus#GO:0050982;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;response to mechanical stimulus#GO:0009612;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037012.1|UniProtKB=A0A2I2ZUA6 A0A2I2ZUA6 PTHR23268:SF30 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA CHAIN MC.7.G5-RELATED cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000024578.2|UniProtKB=A0A2I2Z7F4 A0A2I2Z7F4 PTHR12842:SF3 FI01459P PROTEIN FAM114A2 GORGO|Ensembl=ENSGGOG00000006510.3|UniProtKB=A0A2I2ZGV1 A0A2I2ZGV1 SCARB1 PTHR11923:SF110 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 SCAVENGER RECEPTOR CLASS B MEMBER 1 cargo receptor activity#GO:0038024;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;lipoprotein particle binding#GO:0071813;binding#GO:0005488;low-density lipoprotein particle binding#GO:0030169;protein-lipid complex binding#GO:0071814 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;cell recognition#GO:0008037;endocytosis#GO:0006897;regulation of biological process#GO:0050789;apoptotic cell clearance#GO:0043277;plasma lipoprotein particle clearance#GO:0034381;establishment of localization#GO:0051234;import into cell#GO:0098657;sterol transport#GO:0015918;phagocytosis#GO:0006909;transport#GO:0006810;lipid transport#GO:0006869;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;cellular process#GO:0009987;cholesterol efflux#GO:0033344 membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853;cell periphery#GO:0071944;membrane raft#GO:0045121;caveola#GO:0005901;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell surface#GO:0009986 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000003588.3|UniProtKB=G3QM04 G3QM04 E2F1 PTHR12081:SF43 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000036996.1|UniProtKB=A0A2I2ZRY6 A0A2I2ZRY6 PTHR10623:SF20 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;chromosome segregation#GO:0007059;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule end#GO:1990752;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000016296.3|UniProtKB=G3SA22 G3SA22 BZW1 PTHR14208:SF0 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN EIF5-MIMIC PROTEIN 2 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000024663.2|UniProtKB=G3SEV8 G3SEV8 ZFYVE27 PTHR14543:SF1 PROTRUDIN PROTRUDIN enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of nervous system development#GO:0051960;cell communication#GO:0007154;localization#GO:0051179;system development#GO:0048731;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of growth#GO:0040008;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;macromolecule localization#GO:0033036;regulation of cell size#GO:0008361;cellular response to growth factor stimulus#GO:0071363;positive regulation of axonogenesis#GO:0050772;positive regulation of growth#GO:0045927;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;positive regulation of nervous system development#GO:0051962;cell projection organization#GO:0030030;signaling#GO:0023052;cellular component organization#GO:0016043;response to endogenous stimulus#GO:0009719;protein localization to membrane#GO:0072657;regulation of multicellular organismal development#GO:2000026;regulation of cellular component size#GO:0032535;regulation of axonogenesis#GO:0050770;cell surface receptor signaling pathway#GO:0007166;cellular component assembly#GO:0022607;regulation of cell growth#GO:0001558;regulation of multicellular organismal process#GO:0051239;anatomical structure development#GO:0048856;positive regulation of cell projection organization#GO:0031346;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;localization within membrane#GO:0051668;regulation of cellular process#GO:0050794;endoplasmic reticulum tubular network organization#GO:0071786;response to growth factor#GO:0070848;protein localization to plasma membrane#GO:0072659;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;regulation of cell projection organization#GO:0031344;transport#GO:0006810;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell development#GO:0048468;endoplasmic reticulum organization#GO:0007029;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of cell growth#GO:0030307;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;protein localization to cell periphery#GO:1990778;regulation of anatomical structure size#GO:0090066;positive regulation of cell differentiation#GO:0045597;neuron differentiation#GO:0030182;vesicle-mediated transport#GO:0016192;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;endomembrane system organization#GO:0010256;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;axon#GO:0030424;intracellular organelle#GO:0043229;growth cone#GO:0030426;cell projection#GO:0042995;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;endoplasmic reticulum tubular network#GO:0071782;cell periphery#GO:0071944;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011290.3|UniProtKB=G3S8G2 G3S8G2 PTHR37006:SF1 RETROVIRAL-LIKE ASPARTIC PROTEASE 1 RETROVIRAL-LIKE ASPARTIC PROTEASE 1 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000008376.3|UniProtKB=G3S3F3 G3S3F3 NUP54 PTHR13000:SF0 NUCLEOPORIN P54 NUCLEOPORIN P54 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 localization within membrane#GO:0051668;nucleocytoplasmic transport#GO:0006913;nuclear pore organization#GO:0006999;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;nucleus organization#GO:0006997;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;organelle organization#GO:0006996;protein localization to nucleus#GO:0034504 organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000026199.2|UniProtKB=G3RMK0 G3RMK0 PTHR45820:SF1 FI23527P1 PROTON-COUPLED ZINC ANTIPORTER SLC30A1 transporter regulator activity#GO:0141108;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;zinc ion transmembrane transporter activity#GO:0005385;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;monoatomic ion transmembrane transporter activity#GO:0015075 response to stress#GO:0006950;detoxification of inorganic compound#GO:0061687;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;response to chemical#GO:0042221;detoxification#GO:0098754;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;response to metal ion#GO:0010038;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;metal ion transport#GO:0030001;homeostatic process#GO:0042592;zinc ion transmembrane transport#GO:0071577;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000000747.3|UniProtKB=G3QEN7 G3QEN7 MXD4 PTHR11969:SF4 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000005781.3|UniProtKB=G3S649 G3S649 BABAM1 PTHR15660:SF2 BRISC AND BRCA1-A COMPLEX MEMBER 1 BRISC AND BRCA1-A COMPLEX MEMBER 1 negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;cellular response to stress#GO:0033554;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000016567.3|UniProtKB=G3RKA6 G3RKA6 ELAPOR1 PTHR22727:SF13 PROTEIN CBG13728 ENDOSOME_LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR 1 positive regulation of biological process#GO:0048518;autophagy#GO:0006914;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;biological regulation#GO:0065007;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of cellular component organization#GO:0051130;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;positive regulation of organelle organization#GO:0010638 Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;late endosome#GO:0005770;endomembrane system#GO:0012505;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;lytic vacuole#GO:0000323;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000036248.1|UniProtKB=A0A2I2Z1W0 A0A2I2Z1W0 HAUS2 PTHR16039:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;spindle assembly#GO:0051225;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;centrosome cycle#GO:0007098;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell cycle process#GO:0022402;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;HAUS complex#GO:0070652;mitotic spindle#GO:0072686;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876 GORGO|Ensembl=ENSGGOG00000013062.3|UniProtKB=G3RBA2 G3RBA2 LOC101154259 PTHR38491:SF1 REGULATOR OF HEMOGLOBINIZATION AND ERYTHROID CELL EXPANSION PROTEIN REGULATOR OF HEMOGLOBINIZATION AND ERYTHROID CELL EXPANSION PROTEIN GORGO|Ensembl=ENSGGOG00000010282.3|UniProtKB=G3R447 G3R447 PRXL2B PTHR28630:SF29 FAMILY NOT NAMED PROSTAMIDE_PROSTAGLANDIN F SYNTHASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cellular process#GO:0009987;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;unsaturated fatty acid biosynthetic process#GO:0006636;icosanoid metabolic process#GO:0006690;lipid biosynthetic process#GO:0008610;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;prostaglandin metabolic process#GO:0006693;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001588.3|UniProtKB=G3QGV1 G3QGV1 BECN1 PTHR12768:SF6 BECLIN 1 BECLIN-1 protein binding#GO:0005515;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;phosphatidylinositol 3-kinase binding#GO:0043548 vacuole organization#GO:0007033;localization#GO:0051179;organelle assembly#GO:0070925;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;establishment of localization#GO:0051234;mitophagy#GO:0000423;transport#GO:0006810;vacuolar transport#GO:0007034;cellular response to nutrient levels#GO:0031669;intracellular transport#GO:0046907;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;cellular response to stress#GO:0033554;late endosome to vacuole transport#GO:0045324;response to stimulus#GO:0050896;cellular component organization#GO:0016043;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 membrane protein complex#GO:0098796;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;phosphatidylinositol 3-kinase complex, class III#GO:0035032;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000000243.3|UniProtKB=G3QDC7 G3QDC7 PTHR13315:SF0 METALLO PHOSPHOESTERASE RELATED METALLOPHOSPHOESTERASE 1 esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007575.3|UniProtKB=G3QX79 G3QX79 TRIB3 PTHR22961:SF14 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 3 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein metabolic process#GO:0051247;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000028267.2|UniProtKB=G3RRR0 G3RRR0 PTHR11593:SF11 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008449.3|UniProtKB=A0A2I2ZAN3 A0A2I2ZAN3 AFTPH PTHR16156:SF9 AFTIPHILIN A-RELATED AFTIPHILIN binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515 Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;trans-Golgi network transport vesicle membrane#GO:0012510;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;clathrin vesicle coat#GO:0030125;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;vesicle coat#GO:0030120;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;trans-Golgi network membrane#GO:0032588;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular vesicle#GO:0097708;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015784.3|UniProtKB=G3RIA1 G3RIA1 DKK4 PTHR12113:SF10 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 4 protein binding#GO:0005515;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545 regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000010352.3|UniProtKB=G3R4A9 G3R4A9 LOC101149019 PTHR22597:SF0 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SUZ12 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;constitutive heterochromatin formation#GO:0140719;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000210.3|UniProtKB=G3QD98 G3QD98 MINK1 PTHR47096:SF3 MISSHAPEN LIKE KINASE 1 NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE GORGO|Ensembl=ENSGGOG00000025248.2|UniProtKB=G3S2H2 G3S2H2 TSPAN1 PTHR19282:SF216 TETRASPANIN TETRASPANIN-1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003956.3|UniProtKB=G3RNM5 G3RNM5 RAMP1 PTHR14076:SF3 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;coreceptor activity#GO:0015026 cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;localization within membrane#GO:0051668;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;receptor-mediated endocytosis#GO:0006898;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;macromolecule localization#GO:0033036;monoatomic ion transport#GO:0006811;protein transport#GO:0015031;cellular localization#GO:0051641;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;endocytosis#GO:0006897;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;protein localization to membrane#GO:0072657;calcium ion transport#GO:0006816;import into cell#GO:0098657;protein localization to cell periphery#GO:1990778;response to chemical#GO:0042221;vesicle-mediated transport#GO:0016192;signal transduction#GO:0007165;establishment of protein localization#GO:0045184;cellular process#GO:0009987;receptor internalization#GO:0031623;response to hormone#GO:0009725 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012270.3|UniProtKB=A0A2I2YBS7 A0A2I2YBS7 HTN3 PTHR15057:SF0 STATHERIN HISTATIN-3 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;immune system process#GO:0002376;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cellular process#GO:0009987;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell killing#GO:0001906;defense response#GO:0006952;response to external stimulus#GO:0009605 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000004878.3|UniProtKB=G3QQB5 G3QQB5 TTPA PTHR10174:SF225 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;heterocyclic compound binding#GO:1901363 metabolic process#GO:0008152;cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vitamin transport#GO:0051180;localization#GO:0051179;vitamin E metabolic process#GO:0042360 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000011088.3|UniProtKB=G3R671 G3R671 POU2F2 PTHR11636:SF46 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000001418.3|UniProtKB=G3QGE5 G3QGE5 AVIL PTHR11977:SF33 VILLIN ADVILLIN phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092 actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000007628.3|UniProtKB=G3SHG1 G3SHG1 MEP1A PTHR10127:SF824 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT ALPHA catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000013465.3|UniProtKB=G3S590 G3S590 CLUH PTHR12601:SF54 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3 CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 localization#GO:0051179;mitochondrion localization#GO:0051646;organelle localization#GO:0051640 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000014700.3|UniProtKB=G3RFH4 G3RFH4 MATK PTHR24418:SF399 TYROSINE-PROTEIN KINASE MEGAKARYOCYTE-ASSOCIATED TYROSINE-PROTEIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 GORGO|Ensembl=ENSGGOG00000008622.3|UniProtKB=P79175 P79175 C5AR1 PTHR24225:SF29 CHEMOTACTIC RECEPTOR C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR 1 immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of biological quality#GO:0065008;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987 basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000007362.3|UniProtKB=A0A2I2Y6B2 A0A2I2Y6B2 ZFAT PTHR24388:SF73 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZFAT RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002485.3|UniProtKB=G3QJ62 G3QJ62 ZNF329 PTHR24377:SF1050 IP01015P-RELATED MYOCARDIAL ISCHEMIC PRECONDITIONING UP-REGULATED PROTEIN 1-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000023414.2|UniProtKB=G3RV93 G3RV93 RNASEL PTHR24141:SF4 2-5A-DEPENDENT RIBONUCLEASE 2-5A-DEPENDENT RIBONUCLEASE catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biosynthetic process#GO:0009058;biological regulation#GO:0065007;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;defense response#GO:0006952;response to external stimulus#GO:0009605;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;RNA biosynthetic process#GO:0032774;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;response to virus#GO:0009615;RNA metabolic process#GO:0016070 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000014013.3|UniProtKB=G3RDR2 G3RDR2 YARS1 PTHR11586:SF43 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER TYROSINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000002109.3|UniProtKB=G3QI74 G3QI74 SCN7A PTHR10037:SF14 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 7 SUBUNIT ALPHA transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;system process#GO:0003008;transmission of nerve impulse#GO:0019226;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;inorganic ion homeostasis#GO:0098771;nervous system process#GO:0050877;sensory perception#GO:0007600;transmembrane transport#GO:0055085;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;sensory perception of pain#GO:0019233;sodium ion transport#GO:0006814;action potential#GO:0001508;homeostatic process#GO:0042592;membrane depolarization#GO:0051899;metal ion transport#GO:0030001 transporter complex#GO:1990351;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;axon#GO:0030424;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000014199.3|UniProtKB=G3RE70 G3RE70 FBXO45 PTHR12245:SF7 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN F-BOX_SPRY DOMAIN-CONTAINING PROTEIN 1 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 synapse assembly#GO:0007416;cell junction organization#GO:0034330;catabolic process#GO:0009056;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cell junction assembly#GO:0034329;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;modification-dependent macromolecule catabolic process#GO:0043632;synapse organization#GO:0050808;protein catabolic process#GO:0030163;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;proteasomal protein catabolic process#GO:0010498;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;developmental process#GO:0032502 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;cell junction#GO:0030054;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012107.3|UniProtKB=G3R8T6 G3R8T6 FAM83C PTHR16181:SF29 PROTEIN FAM83A-RELATED PROTEIN FAM83C protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 GORGO|Ensembl=ENSGGOG00000044155.1|UniProtKB=G3RN26 G3RN26 BORCS8 PTHR21146:SF3 MEF2B PROTEIN BLOC-1-RELATED COMPLEX SUBUNIT 8 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 p38 MAPK pathway#P05918>MEF#P06023 GORGO|Ensembl=ENSGGOG00000009696.4|UniProtKB=G3R2M2 G3R2M2 ADAMTS12 PTHR13723:SF189 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 12 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000010767.3|UniProtKB=G3S4J0 G3S4J0 DCUN1D1 PTHR12281:SF10 RP42 RELATED DCN1-LIKE PROTEIN 1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746 positive regulation of protein metabolic process#GO:0051247;regulation of protein modification process#GO:0031399;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023949.2|UniProtKB=G3RM56 G3RM56 PTHR24543:SF295 MULTICOPPER OXIDASE-RELATED RETINOSCHISIN developmental process#GO:0032502;sensory organ development#GO:0007423;anatomical structure formation involved in morphogenesis#GO:0048646;animal organ development#GO:0048513;multicellular organism development#GO:0007275;camera-type eye morphogenesis#GO:0048593;sensory system development#GO:0048880;retina development in camera-type eye#GO:0060041;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;visual system development#GO:0150063;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000026781.2|UniProtKB=G3S6A8 G3S6A8 ARHGAP30 PTHR15729:SF12 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 30 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000005725.3|UniProtKB=G3QSG9 G3QSG9 CDKN3 PTHR23339:SF103 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE CYCLIN-DEPENDENT KINASE INHIBITOR 3 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000013745.3|UniProtKB=G3RD14 G3RD14 ZNF782 PTHR24377:SF782 IP01015P-RELATED ZINC FINGER PROTEIN 782 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008944.3|UniProtKB=G3R0Q6 G3R0Q6 PPP4R4 PTHR21467:SF0 PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4 SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000012161.3|UniProtKB=G3R907 G3R907 TIAM2 PTHR46001:SF5 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR TIAM2 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of axonogenesis#GO:0050770;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 GORGO|Ensembl=ENSGGOG00000008315.3|UniProtKB=G3QZ28 G3QZ28 PRPS2 PTHR10210:SF123 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007417.3|UniProtKB=G3QWT8 G3QWT8 PGBD4 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000008010.4|UniProtKB=A0A2I2YWP0 A0A2I2YWP0 ITPR2 PTHR45816:SF3 MIR DOMAIN-CONTAINING PROTEIN INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR GORGO|Ensembl=ENSGGOG00000005173.3|UniProtKB=G3QR40 G3QR40 UBE3C PTHR45700:SF2 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3C ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 GORGO|Ensembl=ENSGGOG00000001961.3|UniProtKB=G3QHU6 G3QHU6 CASP9 PTHR10454:SF157 CASPASE CASPASE-9 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233 positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;biological regulation#GO:0065007;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;apoptotic signaling pathway#GO:0097190;positive regulation of apoptotic process#GO:0043065;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;DNA damage response#GO:0006974 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 PI3 kinase pathway#P00048>Caspase-9#P01197;FAS signaling pathway#P00020>Pro-Caspase9#P00603;VEGF signaling pathway#P00056>Caspase9#P01410;FAS signaling pathway#P00020>Caspase9#P00593;Angiogenesis#P00005>Caspase 9#P00216;Apoptosis signaling pathway#P00006>Caspase 9#P00298 GORGO|Ensembl=ENSGGOG00000040247.1|UniProtKB=A0A2I2YKA7 A0A2I2YKA7 PTHR46035:SF2 TETRATRICOPEPTIDE REPEAT PROTEIN 4 CNS1_TTC4 WHEEL DOMAIN-CONTAINING PROTEIN heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000011838.3|UniProtKB=G3R848 G3R848 TXNIP PTHR11188:SF14 ARRESTIN DOMAIN CONTAINING PROTEIN THIOREDOXIN-INTERACTING PROTEIN enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 response to oxidative stress#GO:0006979;response to stimulus#GO:0050896;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000007690.3|UniProtKB=A0A2I2ZS43 A0A2I2ZS43 TCTE1 PTHR24107:SF27 YNEIN REGULATORY COMPLEX SUBUNIT 5 DYNEIN REGULATORY COMPLEX SUBUNIT 5 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000014339.3|UniProtKB=G3REJ3 G3REJ3 HIGD2A PTHR12297:SF11 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 2A, MITOCHONDRIAL cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000028474.2|UniProtKB=G3RUI3 G3RUI3 PTHR13287:SF5 ADIPOSE-SECRETED SIGNALING PROTEIN SUBFAMILY NOT NAMED multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal-level homeostasis#GO:0048871;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;temperature homeostasis#GO:0001659;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;homeostatic process#GO:0042592;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adaptive thermogenesis#GO:1990845 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000024395.2|UniProtKB=G3S571 G3S571 FAM167B PTHR32289:SF4 PROTEIN FAM167A PROTEIN FAM167B GORGO|Ensembl=ENSGGOG00000010503.3|UniProtKB=G3R4N9 G3R4N9 EEF2KMT PTHR14614:SF117 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT-RELATED catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009927.3|UniProtKB=G3R374 G3R374 DNAJA3 PTHR44145:SF6 DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000001938.3|UniProtKB=G3QHS5 G3QHS5 TRIM29 PTHR25465:SF7 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 29 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000010893.3|UniProtKB=G3R5N5 G3R5N5 RETREG3 PTHR28659:SF1 RETICULON-LIKE PROTEIN RETICULOPHAGY REGULATOR 3 GORGO|Ensembl=ENSGGOG00000010419.3|UniProtKB=G3R4G2 G3R4G2 CDC20 PTHR19918:SF3 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;binding#GO:0005488 primary metabolic process#GO:0044238;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;positive regulation of metabolic process#GO:0009893;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008125.3|UniProtKB=G3QYK3 G3QYK3 PTHR11610:SF2 LIPASE HEPATIC TRIACYLGLYCEROL LIPASE hydrolase activity, acting on ester bonds#GO:0016788;binding#GO:0005488;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 Triacylglycerol metabolism#P02782>Triacylglycerol lipase#P03205 GORGO|Ensembl=ENSGGOG00000013828.3|UniProtKB=G3RD91 G3RD91 WFDC1 PTHR14308:SF0 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 regulation of growth#GO:0040008;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell growth#GO:0001558;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000038407.1|UniProtKB=A0A2I2ZQF0 A0A2I2ZQF0 GMNC PTHR13372:SF2 GEMININ GEMININ COILED-COIL DOMAIN-CONTAINING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA replication#GO:0006275;biological regulation#GO:0065007;regulation of DNA-templated DNA replication initiation#GO:0030174;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000036120.1|UniProtKB=A0A2I2YTK3 A0A2I2YTK3 PTHR13624:SF3 RE42071P TRANSMEMBRANE PROTEIN 161B GORGO|Ensembl=ENSGGOG00000023598.2|UniProtKB=G3S0S1 G3S0S1 PTHR11819:SF150 SOLUTE CARRIER FAMILY 5 SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012410.3|UniProtKB=A0A2I2Y251 A0A2I2Y251 FGD6 PTHR12673:SF12 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 6 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000025378.2|UniProtKB=G3RRY6 G3RRY6 HNRNPH3 PTHR13976:SF36 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009999.3|UniProtKB=G3R3D8 G3R3D8 RPS6KB2 PTHR24351:SF171 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE BETA-2 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 TOR signaling#GO:0031929;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;TORC1 signaling#GO:0038202 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protein modifying enzyme#PC00260 PI3 kinase pathway#P00048>S6K#P01194;PDGF signaling pathway#P00047>p90RSK#P01142;p53 pathway by glucose deprivation#P04397>S6K#P04636;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 GORGO|Ensembl=ENSGGOG00000011458.3|UniProtKB=G3R750 G3R750 MAN1C1 PTHR11742:SF28 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IC hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000000354.4|UniProtKB=A0A2I2Z4Z3 A0A2I2Z4Z3 LDB2 PTHR10378:SF8 LIM DOMAIN-BINDING PROTEIN LIM DOMAIN-BINDING PROTEIN 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000009547.3|UniProtKB=G3R2A2 G3R2A2 CNOT1 PTHR13162:SF8 CCR4-NOT TRANSCRIPTION COMPLEX CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;CCR4-NOT complex#GO:0030014;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000025450.2|UniProtKB=G3S488 G3S488 LOC101124743 PTHR26454:SF10 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6V1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012066.3|UniProtKB=G3R8Q4 G3R8Q4 MPEG1 PTHR31463:SF4 MACROPHAGE-EXPRESSED GENE 1 PROTEIN MACROPHAGE-EXPRESSED GENE 1 PROTEIN defense response#GO:0006952;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 GORGO|Ensembl=ENSGGOG00000004503.3|UniProtKB=G3QPC9 G3QPC9 XPNPEP1 PTHR43763:SF6 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 1 protease#PC00190 GORGO|Ensembl=ENSGGOG00000027332.3|UniProtKB=G3S760 G3S760 TECRL PTHR10556:SF27 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE TRANS-2,3-ENOYL-COA REDUCTASE-LIKE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003093.3|UniProtKB=G3QKR0 G3QKR0 SMCR8 PTHR31334:SF1 SMITH-MAGENIS SYNDROME REGION GENE 8 PROTEIN GUANINE NUCLEOTIDE EXCHANGE PROTEIN SMCR8 protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000001083.3|UniProtKB=G3QFJ4 G3QFJ4 PTHR23285:SF3 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3D RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000037407.1|UniProtKB=A0A2I2Z7T7 A0A2I2Z7T7 RBBP7 PTHR22850:SF82 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP7 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000009406.3|UniProtKB=G3R1W4 G3R1W4 CASKIN2 PTHR24174:SF18 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 CASKIN-2 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004279.3|UniProtKB=G3QNS5 G3QNS5 PTHR14995:SF2 AMNIONLESS PROTEIN AMNIONLESS renal absorption#GO:0070293;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;transport#GO:0006810;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;macromolecule localization#GO:0033036;cellular process#GO:0009987;renal system process#GO:0003014 apical part of cell#GO:0045177;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708 GORGO|Ensembl=ENSGGOG00000024643.2|UniProtKB=G3SAH8 G3SAH8 LOC101128867 PTHR26453:SF32 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004370.3|UniProtKB=A0A2I2YNK1 A0A2I2YNK1 SLC30A6 PTHR46531:SF1 ZINC TRANSPORTER 6 ZINC TRANSPORTER 6 zinc ion transport#GO:0006829;metal ion transport#GO:0030001;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040981.1|UniProtKB=A0A2I2ZGB8 A0A2I2ZGB8 PDK1 PTHR11947:SF14 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 1, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004708.3|UniProtKB=G3QPV9 G3QPV9 PRAP1 PTHR37861:SF1 PROLINE-RICH ACIDIC PROTEIN 1 PROLINE-RICH ACIDIC PROTEIN 1 GORGO|Ensembl=ENSGGOG00000000217.3|UniProtKB=G3SBC9 G3SBC9 GP1BA PTHR24366:SF158 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS PLATELET GLYCOPROTEIN IB ALPHA CHAIN immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000012358.3|UniProtKB=G3R9J1 G3R9J1 ADAMTS14 PTHR13723:SF24 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 14 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;external encapsulating structure organization#GO:0045229;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000015555.3|UniProtKB=G3RPN5 G3RPN5 PTHR10751:SF102 GUANYLATE BINDING PROTEIN GB1_RHD3-TYPE G DOMAIN-CONTAINING PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 G-protein#PC00020;heterotrimeric G-protein#PC00117 GORGO|Ensembl=ENSGGOG00000010209.3|UniProtKB=A0A2I2ZYC7 A0A2I2ZYC7 ENDOV PTHR28511:SF1 ENDONUCLEASE V ENDONUCLEASE V binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;single-stranded RNA binding#GO:0003727;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013873.3|UniProtKB=G3SGR6 G3SGR6 EVPL PTHR23169:SF7 ENVOPLAKIN ENVOPLAKIN cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular component organization#GO:0016043;response to stress#GO:0006950;response to wounding#GO:0009611;organelle organization#GO:0006996;wound healing#GO:0042060;cellular component organization or biogenesis#GO:0071840;intermediate filament-based process#GO:0045103 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane#GO:0016020 intermediate filament#PC00129;intermediate filament binding protein#PC00130 GORGO|Ensembl=ENSGGOG00000041642.1|UniProtKB=A0A2I2YGY6 A0A2I2YGY6 TIFA PTHR31266:SF2 TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A FAMILY MEMBER TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A cellular process#GO:0009987;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;positive regulation of signaling#GO:0023056;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;activation of innate immune response#GO:0002218;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;innate immune response-activating signaling pathway#GO:0002758;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;intracellular receptor signaling pathway#GO:0030522;response to external biotic stimulus#GO:0043207;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005146.3|UniProtKB=G3QR08 G3QR08 ZNF669 PTHR24379:SF104 KRAB AND ZINC FINGER DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000038396.1|UniProtKB=A0A2I2Z6B2 A0A2I2Z6B2 PTHR23158:SF55 MELANOMA INHIBITORY ACTIVITY-RELATED MIA SH3 DOMAIN ER EXPORT FACTOR 2 intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;protein secretion#GO:0009306;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;secretion by cell#GO:0032940;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000022097.2|UniProtKB=A0A2I2YAA0 A0A2I2YAA0 UROD PTHR21091:SF169 METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED UROPORPHYRINOGEN DECARBOXYLASE catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;porphyrin-containing compound biosynthetic process#GO:0006779;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 methyltransferase#PC00155 Heme biosynthesis#P02746>Uroporphyrinogen decarboxylase#P02975 GORGO|Ensembl=ENSGGOG00000010103.3|UniProtKB=G3R3M8 G3R3M8 PTHR17597:SF0 MEMBRANE PROTEIN MLC1 MEMBRANE PROTEIN MLC1 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of response to stress#GO:0080134;biological regulation#GO:0065007 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000010962.3|UniProtKB=G3R5V3 G3R5V3 FBXL5 PTHR13318:SF19 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 5 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000008044.3|UniProtKB=G3SC97 G3SC97 ZNF229 PTHR24381:SF488 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 227 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016143.3|UniProtKB=G3RR05 G3RR05 EVX1 PTHR46294:SF2 SEGMENTATION PROTEIN EVEN-SKIPPED HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000005906.3|UniProtKB=G3QSZ0 G3QSZ0 COL19A1 PTHR24023:SF938 COLLAGEN ALPHA COLLAGEN ALPHA-1(XIX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000011318.3|UniProtKB=G3R6S2 G3R6S2 FUBP3 PTHR10288:SF234 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 3 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000024146.2|UniProtKB=G3S134 G3S134 PTHR24103:SF567 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 77 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;immune system process#GO:0002376;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000010952.3|UniProtKB=G3R5T9 G3R5T9 FOSB PTHR23351:SF3 FOS TRANSCRIPTION FACTOR-RELATED PROTEIN FOSB RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>Fosb#G06666;Gonadotropin-releasing hormone receptor pathway#P06664>Fosb#G06878;Gonadotropin-releasing hormone receptor pathway#P06664>FOS#P06709 GORGO|Ensembl=ENSGGOG00000014062.4|UniProtKB=G3RDW8 G3RDW8 PTHR24278:SF26 COAGULATION FACTOR COAGULATION FACTOR VII endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;hemostasis#GO:0007599;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;wound healing#GO:0042060;protein metabolic process#GO:0019538;coagulation#GO:0050817;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to wounding#GO:0009611;response to stress#GO:0006950;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;metabolic process#GO:0008152;blood coagulation#GO:0007596;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>FVII#P00454;Angiogenesis#P00005>FVIIa#P00201;Blood coagulation#P00011>FVIIa#P00447 GORGO|Ensembl=ENSGGOG00000007161.3|UniProtKB=G3QW63 G3QW63 NAA25 PTHR22767:SF3 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 protein acetyltransferase complex#GO:0031248;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000024218.2|UniProtKB=A0A2I2ZRV7 A0A2I2ZRV7 CCN5 PTHR11348:SF22 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 5 glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178 regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;cell adhesion#GO:0007155;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207;growth factor#PC00112 GORGO|Ensembl=ENSGGOG00000028356.2|UniProtKB=G3S7A3 G3S7A3 PPP6C PTHR45619:SF67 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 CATALYTIC SUBUNIT hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PP2A#P00547 GORGO|Ensembl=ENSGGOG00000000408.3|UniProtKB=G3RQG9 G3RQG9 RUSC1 PTHR15591:SF11 RUN AND SH3 DOMAIN CONTAINING AP-4 COMPLEX ACCESSORY SUBUNIT RUSC1 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013012.3|UniProtKB=G3RB57 G3RB57 ZBTB49 PTHR24390:SF205 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 49 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015885.3|UniProtKB=G3RIJ0 G3RIJ0 XRCC6 PTHR12604:SF5 KU AUTOANTIGEN DNA HELICASE DNA REPAIR PROTEIN KU70 binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;telomeric repeat DNA binding#GO:0042162;DNA binding#GO:0003677 nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA helicase#PC00011 GORGO|Ensembl=ENSGGOG00000011147.3|UniProtKB=G3S1C3 G3S1C3 PTK2 PTHR24418:SF78 TYROSINE-PROTEIN KINASE FOCAL ADHESION KINASE 1 catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;non-membrane spanning protein tyrosine kinase activity#GO:0004715 positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;cell surface receptor signaling pathway#GO:0007166;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;anchoring junction#GO:0070161;cell junction#GO:0030054 non-receptor tyrosine protein kinase#PC00168 VEGF signaling pathway#P00056>FAK#P01420;Integrin signalling pathway#P00034>FAK#P00932;Gonadotropin-releasing hormone receptor pathway#P06664>FAK#P06707;Angiogenesis#P00005>FAK#P00209;CCKR signaling map#P06959>FAK1#P07129 GORGO|Ensembl=ENSGGOG00000013165.3|UniProtKB=A0A2I2YAN9 A0A2I2YAN9 PTHR10388:SF43 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 SUI1 DOMAIN-CONTAINING PROTEIN ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;nucleic acid binding#GO:0003676;binding#GO:0005488;translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000008752.3|UniProtKB=A0A2I2ZDJ9 A0A2I2ZDJ9 LOC101131103 PTHR26451:SF52 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000010968.3|UniProtKB=G3R5Z0 G3R5Z0 ADGRV1 PTHR46682:SF1 ADHESION G-PROTEIN COUPLED RECEPTOR V1 ADHESION G PROTEIN-COUPLED RECEPTOR V1 molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;molecular transducer activity#GO:0060089;enzyme regulator activity#GO:0030234;adenylate cyclase regulator activity#GO:0010854;transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibitor activity#GO:0010855;cyclase inhibitor activity#GO:0010852;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;enzyme inhibitor activity#GO:0004857;cyclase regulator activity#GO:0010851 cellular response to chemical stimulus#GO:0070887;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;response to metal ion#GO:0010038;nervous system process#GO:0050877;response to calcium ion#GO:0051592;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;sensory perception of sound#GO:0007605;visual perception#GO:0007601;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501 stereocilium#GO:0032420;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000025913.2|UniProtKB=A0A2I2YXD1 A0A2I2YXD1 KRBA2 PTHR45935:SF2 PROTEIN ZBED8-RELATED KRAB DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000006812.3|UniProtKB=A0A2I2YMU1 A0A2I2YMU1 TAS1R1 PTHR24061:SF3 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011248.3|UniProtKB=G3R6K7 G3R6K7 RASD1 PTHR46149:SF4 MIP08469P DEXAMETHASONE-INDUCED RAS-RELATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000007497.3|UniProtKB=G3QX15 G3QX15 SLC6A12 PTHR11616:SF118 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT BETAINE TRANSPORTER carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000042519.1|UniProtKB=A0A2I2ZSM0 A0A2I2ZSM0 UBE2D4 PTHR24068:SF541 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D4 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein K11-linked ubiquitination#GO:0070979;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein K63-linked ubiquitination#GO:0070534;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000014106.3|UniProtKB=G3RE07 G3RE07 EPHB1 PTHR46877:SF17 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199 system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 GORGO|Ensembl=ENSGGOG00000000194.3|UniProtKB=A0A2I2Y6Z9 A0A2I2Y6Z9 DPYSL2 PTHR11647:SF56 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;dihydropyrimidinase activity#GO:0004157;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 GORGO|Ensembl=ENSGGOG00000013030.3|UniProtKB=G3RB74 G3RB74 DHODH PTHR48109:SF4 DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;pyrimidine nucleobase metabolic process#GO:0006206;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;ribonucleotide metabolic process#GO:0009259 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydrooratate oxidase#P02927 GORGO|Ensembl=ENSGGOG00000013018.3|UniProtKB=A0A2I2Z0G4 A0A2I2Z0G4 GABRD PTHR18945:SF34 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT DELTA ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820 cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;GABA-ergic synapse#GO:0098982;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000042425.1|UniProtKB=A0A2I2YI34 A0A2I2YI34 PTHR46254:SF12 PROTEIN GVQW1-RELATED SMALL INTEGRAL MEMBRANE PROTEIN 11 GORGO|Ensembl=ENSGGOG00000006092.3|UniProtKB=G3S6Z9 G3S6Z9 HDC PTHR11999:SF68 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE HISTIDINE DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;amine metabolic process#GO:0009308;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;lyase#PC00144 CCKR signaling map#P06959>HDC#G07262;CCKR signaling map#P06959>HDC#G06969;Histamine synthesis#P04387>Histidine decarboxylase#P04493 GORGO|Ensembl=ENSGGOG00000004259.3|UniProtKB=G3QNR0 G3QNR0 FARP2 PTHR45858:SF4 FERM DOMAIN CONTAINING PROTEIN FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 GORGO|Ensembl=ENSGGOG00000027218.2|UniProtKB=G3S0P8 G3S0P8 RDX PTHR23281:SF14 MERLIN/MOESIN/EZRIN/RADIXIN RADIXIN protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of anatomical structure morphogenesis#GO:0022603 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;filopodium#GO:0030175 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000008707.3|UniProtKB=G3R037 G3R037 LOC101142994 PTHR24173:SF12 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG A ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of response to stress#GO:0080134;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;proteasomal protein catabolic process#GO:0010498;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;protein catabolic process#GO:0030163;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;catabolic process#GO:0009056;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009669.3|UniProtKB=A0A2I2Y339 A0A2I2Y339 GRK6 PTHR24355:SF15 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 6 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK6#P05939;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GPRK#P00840 GORGO|Ensembl=ENSGGOG00000001063.3|UniProtKB=G3QFH5 G3QFH5 CTCF PTHR24403:SF73 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR CTCF double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000006103.3|UniProtKB=G3QTF3 G3QTF3 KLHL40 PTHR24412:SF22 KELCH PROTEIN KELCH-LIKE PROTEIN 40 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 animal organ development#GO:0048513;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;striated muscle cell differentiation#GO:0051146;muscle organ development#GO:0007517;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;striated muscle tissue development#GO:0014706;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;proteasomal protein catabolic process#GO:0010498;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;regulation of post-translational protein modification#GO:1901873;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;protein catabolic process#GO:0030163;negative regulation of protein ubiquitination#GO:0031397;modification-dependent macromolecule catabolic process#GO:0043632;cell differentiation#GO:0030154;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;negative regulation of metabolic process#GO:0009892;cell development#GO:0048468;negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;regulation of protein modification process#GO:0031399;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;developmental process#GO:0032502;regulation of protein ubiquitination#GO:0031396;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;skeletal muscle tissue development#GO:0007519;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;negative regulation of catabolic process#GO:0009895;muscle tissue development#GO:0060537;regulation of protein catabolic process#GO:0042176;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of protein metabolic process#GO:0051248;muscle cell development#GO:0055001;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;muscle cell differentiation#GO:0042692 transferase complex#GO:1990234;I band#GO:0031674;Cul3-RING ubiquitin ligase complex#GO:0031463;sarcomere#GO:0030017;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;A band#GO:0031672;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013145.3|UniProtKB=G3RBH1 G3RBH1 BMPER PTHR11339:SF272 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED BMP-BINDING ENDOTHELIAL REGULATOR PROTEIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 vasculature development#GO:0001944;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of vasculature development#GO:1901342;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of angiogenesis#GO:0045765;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of developmental process#GO:0050793;circulatory system development#GO:0072359;regulation of multicellular organismal development#GO:2000026;blood vessel development#GO:0001568;regulation of biological process#GO:0050789 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000034993.2|UniProtKB=A0A2I2Y4R6 A0A2I2Y4R6 GOLGA3 PTHR18902:SF26 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GOLGIN SUBFAMILY A MEMBER 3 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000005739.3|UniProtKB=G3QSH9 G3QSH9 CLDN19 PTHR12002:SF27 CLAUDIN CLAUDIN-19 binding#GO:0005488;transporter activity#GO:0005215;cell adhesion mediator activity#GO:0098631;paracellular tight junction channel activity#GO:0160187;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell junction organization#GO:0034330;visual system development#GO:0150063;sensory organ development#GO:0007423;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;transport#GO:0006810;cell-cell junction assembly#GO:0007043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;animal organ development#GO:0048513;establishment of localization#GO:0051234;cellular component biogenesis#GO:0044085;sensory system development#GO:0048880;cellular process#GO:0009987;cellular component assembly#GO:0022607;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;retina development in camera-type eye#GO:0060041 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000002037.3|UniProtKB=G3QI15 G3QI15 EDEM1 PTHR45679:SF5 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1 cellular process#GO:0009987;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;biological regulation#GO:0065007;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 GORGO|Ensembl=ENSGGOG00000014590.3|UniProtKB=A0A2I2Y9D5 A0A2I2Y9D5 GNL1 PTHR45709:SF3 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 1 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 GORGO|Ensembl=ENSGGOG00000023510.2|UniProtKB=G3SJ85 G3SJ85 FBXO39 PTHR10706:SF160 F-BOX FAMILY PROTEIN F-BOX ONLY PROTEIN 39 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000024612.2|UniProtKB=G3RN23 G3RN23 PKIG PTHR15416:SF5 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR GAMMA protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 kinase inhibitor#PC00139;kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000003891.3|UniProtKB=G3QMS0 G3QMS0 ULBP3 PTHR16675:SF199 MHC CLASS I-RELATED UL16-BINDING PROTEIN 3 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biological process#GO:0050789;natural killer cell mediated immunity#GO:0002228;leukocyte mediated cytotoxicity#GO:0001909;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;defense response to other organism#GO:0098542;immune effector process#GO:0002252;natural killer cell mediated cytotoxicity#GO:0042267;regulation of leukocyte mediated immunity#GO:0002703;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;cell killing#GO:0001906;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000012548.3|UniProtKB=G3R9Z3 G3R9Z3 MVD PTHR10977:SF3 DIPHOSPHOMEVALONATE DECARBOXYLASE DIPHOSPHOMEVALONATE DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407;isoprenoid biosynthetic process#GO:0008299;acetyl-CoA metabolic process#GO:0006084 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 lyase#PC00144;decarboxylase#PC00089 Cholesterol biosynthesis#P00014>Diphosphomevalonate decarboxylase#P00496 GORGO|Ensembl=ENSGGOG00000006820.3|UniProtKB=G3QVB0 G3QVB0 LOC101133375 PTHR14952:SF12 ROPPORIN-1-LIKE PROTEIN ROPPORIN-1B cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;sperm capacitation#GO:0048240;male gamete generation#GO:0048232;developmental maturation#GO:0021700;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;cell maturation#GO:0048469;sperm motility#GO:0097722;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;developmental process involved in reproduction#GO:0003006;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;gamete generation#GO:0007276;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell differentiation#GO:0030154;spermatid development#GO:0007286;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285 cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000016988.3|UniProtKB=G3S0D1 G3S0D1 PLIN4 PTHR47538:SF1 PERILIPIN 4 PERILIPIN-4 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000179.3|UniProtKB=A0A2I2ZCH9 A0A2I2ZCH9 MGLL PTHR11614:SF198 PHOSPHOLIPASE-RELATED MONOGLYCERIDE LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;catalytic activity#GO:0003824 membrane#GO:0016020;cellular anatomical structure#GO:0110165 phospholipase#PC00186;lipase#PC00143 GORGO|Ensembl=ENSGGOG00000000634.3|UniProtKB=A0A2I2YQU4 A0A2I2YQU4 ELAVL4 PTHR10352:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 4 negative regulation of catabolic process#GO:0009895;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of RNA stability#GO:0043487;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;mRNA stabilization#GO:0048255;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518 neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell body#GO:0044297;nucleus#GO:0005634;perikaryon#GO:0043204;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000015204.3|UniProtKB=G3S8P1 G3S8P1 PTHR23254:SF16 EIF4G DOMAIN PROTEIN CBP80_20-DEPENDENT TRANSLATION INITIATION FACTOR translation regulator activity#GO:0045182 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007932.3|UniProtKB=G3QY33 G3QY33 SRARP PTHR38494:SF1 STEROID RECEPTOR-ASSOCIATED AND REGULATED PROTEIN STEROID RECEPTOR-ASSOCIATED AND REGULATED PROTEIN nuclear estrogen receptor binding#GO:0030331;transcription factor binding#GO:0008134;binding#GO:0005488;nuclear receptor binding#GO:0016922;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;positive regulation of intracellular signal transduction#GO:1902533;regulation of intracellular signal transduction#GO:1902531 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000007899.3|UniProtKB=A0A2I2YXF0 A0A2I2YXF0 DOCK10 PTHR23317:SF71 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 10 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;system development#GO:0048731;synapse organization#GO:0050808;dendritic spine morphogenesis#GO:0060997;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;postsynapse organization#GO:0099173;regulation of cell communication#GO:0010646;dendritic spine development#GO:0060996;dendrite morphogenesis#GO:0048813;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;dendritic spine organization#GO:0097061;cellular process#GO:0009987;dendrite development#GO:0016358;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;cell projection organization#GO:0030030;cell differentiation#GO:0030154;neuron projection organization#GO:0106027;regulation of Rho protein signal transduction#GO:0035023;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000009674.3|UniProtKB=G3S8G0 G3S8G0 PALLD PTHR13817:SF106 TITIN PALLADIN structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 A band#GO:0031672;contractile muscle fiber#GO:0043292;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;M band#GO:0031430;intracellular organelle#GO:0043229;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000016644.3|UniProtKB=G3RKI2 G3RKI2 ANO5 PTHR12308:SF23 ANOCTAMIN ANOCTAMIN-5 intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003603.3|UniProtKB=G3QM12 G3QM12 INHA PTHR11848:SF117 TGF-BETA FAMILY INHIBIN ALPHA CHAIN cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inha#P06855 GORGO|Ensembl=ENSGGOG00000015513.3|UniProtKB=G3RHL0 G3RHL0 GDF5 PTHR11848:SF44 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 5 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;regulation of cell differentiation#GO:0045595;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;positive regulation of developmental process#GO:0051094;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000016431.3|UniProtKB=G3RJY3 G3RJY3 UAP1 PTHR11952:SF4 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine biosynthetic process#GO:0006048 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000007814.3|UniProtKB=G3S0R0 G3S0R0 ITGA6 PTHR23220:SF9 INTEGRIN ALPHA INTEGRIN ALPHA-6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;immune system process#GO:0002376;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell migration#GO:0016477;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;leukocyte migration#GO:0050900;cell surface receptor signaling pathway#GO:0007166 integrin complex#GO:0008305;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000000693.3|UniProtKB=G3QEI6 G3QEI6 RNF139 PTHR22763:SF163 RING ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF139 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000023623.2|UniProtKB=G3SGL1 G3SGL1 TLR3 PTHR24365:SF524 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014949.4|UniProtKB=A0A2I2YTZ8 A0A2I2YTZ8 RIC8B PTHR12425:SF2 SYNEMBRYN CHAPERONE RIC-8B guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016202.3|UniProtKB=G3RJC4 G3RJC4 SLC39A4 PTHR12191:SF21 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP4 transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804 transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000006556.3|UniProtKB=G3QUL3 G3QUL3 SORT1 PTHR12106:SF23 SORTILIN RELATED SORTILIN vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;endocytosis#GO:0006897;Golgi to endosome transport#GO:0006895;cellular component organization#GO:0016043;post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;cellular localization#GO:0051641 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000043435.1|UniProtKB=A0A2I2Y582 A0A2I2Y582 NAALADL2 PTHR10404:SF32 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE INACTIVE N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE-LIKE PROTEIN 2 exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000004474.3|UniProtKB=G3QP96 G3QP96 RNLS PTHR23357:SF1 RENALASE RENALASE catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000002668.3|UniProtKB=G3QJM7 G3QJM7 ZNF134 PTHR24399:SF4 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER PROTEIN 134 DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007657.3|UniProtKB=A0A2I2ZTA2 A0A2I2ZTA2 PTHR24342:SF6 SERINE/THREONINE-PROTEIN KINASE 17 SERINE_THREONINE-PROTEIN KINASE 17A transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000009369.3|UniProtKB=G3R1S1 G3R1S1 OVCA2 PTHR48070:SF6 ESTERASE OVCA2 ESTERASE OVCA2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 esterase#PC00097;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000038420.1|UniProtKB=A0A2I2ZSX6 A0A2I2ZSX6 LOC101130507 PTHR24384:SF257 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 709-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000001835.3|UniProtKB=G3QHI0 G3QHI0 TM4SF4 PTHR14198:SF15 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 4 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000016262.2|UniProtKB=A0A2I2Y9K7 A0A2I2Y9K7 LOC101125257 PTHR48018:SF90 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AK3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040633.1|UniProtKB=A0A2I2Z2G8 A0A2I2Z2G8 MAPK14 PTHR24055:SF110 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 14 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>p38#P00644;EGF receptor signaling pathway#P00018>p38#P00562;B cell activation#P00010>p38#P00384;TGF-beta signaling pathway#P00052>P38#P01275;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;VEGF signaling pathway#P00056>p38MAPK#P01423;JAK/STAT signaling pathway#P00038>Serine kinase#P01029;Parkinson disease#P00049>p38 MAPK#P01212;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Oxidative stress response#P00046>p38#P01135;p38 MAPK pathway#P05918>p38alpha#P06031;CCKR signaling map#P06959>p38MAPK#P07079;Toll receptor signaling pathway#P00054>p38#P01352;Angiogenesis#P00005>p38MAPK#P00182;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;CCKR signaling map#P06959>MAPKAP-K2#P07217;Ras Pathway#P04393>p38#P04558 GORGO|Ensembl=ENSGGOG00000026764.2|UniProtKB=G3R245 G3R245 HMGB1 PTHR48112:SF11 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B1 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 p53 pathway#P00059>HMG1#P04619 GORGO|Ensembl=ENSGGOG00000003637.3|UniProtKB=G3QM49 G3QM49 LCN1 PTHR11430:SF136 LIPOCALIN LIPOCALIN-1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000043182.1|UniProtKB=A0A2I2YNV2 A0A2I2YNV2 PTHR13220:SF13 TIMELESS INTERACTING-RELATED TIMELESS-INTERACTING PROTEIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;negative regulation of DNA metabolic process#GO:0051053;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;negative regulation of DNA-templated DNA replication#GO:2000104;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA replication#GO:0006275;DNA-templated DNA replication#GO:0006261 organelle lumen#GO:0043233;chromosome#GO:0005694;replication fork#GO:0005657;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000003675.3|UniProtKB=G3SDB6 G3SDB6 CNOT6 PTHR12121:SF33 CARBON CATABOLITE REPRESSOR PROTEIN 4 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6 catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;CCR4-NOT complex#GO:0030014 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000014658.3|UniProtKB=G3RFD6 G3RFD6 LACTB PTHR46520:SF1 SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;regulation of lipid metabolic process#GO:0019216;proteolysis#GO:0006508;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biological process#GO:0050789 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000003847.3|UniProtKB=G3QMN1 G3QMN1 OR2T10 PTHR26453:SF734 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T10 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040234.1|UniProtKB=A0A2I2ZE33 A0A2I2ZE33 PTHR21528:SF2 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 SUBFAMILY NOT NAMED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000001412.3|UniProtKB=G3S1L5 G3S1L5 COPB1 PTHR10635:SF0 COATOMER SUBUNIT BETA COATOMER SUBUNIT BETA Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 intracellular membrane-bounded organelle#GO:0043231;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;COPI-coated vesicle#GO:0030137;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000015947.3|UniProtKB=G3RIP6 G3RIP6 PLTP PTHR10504:SF16 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED PHOSPHOLIPID TRANSFER PROTEIN transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014 transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;multicellular organismal process#GO:0032501;lipid transport#GO:0006869;phospholipid transport#GO:0015914;biological regulation#GO:0065007;lipid localization#GO:0010876;localization#GO:0051179;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;organophosphate ester transport#GO:0015748;ceramide transport#GO:0035627 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000037242.1|UniProtKB=A0A2I2Z933 A0A2I2Z933 PTHR13958:SF5 CENTROSOME-ASSOCIATED PROTEIN 350 COILED-COIL DOMAIN-CONTAINING PROTEIN 187 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000009323.3|UniProtKB=G3R1N1 G3R1N1 FOXN4 PTHR13962:SF17 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N4 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000043482.1|UniProtKB=A0A2I2ZAW7 A0A2I2ZAW7 COG5 PTHR13228:SF3 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;COG complex#GO:0017119;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000005082.3|UniProtKB=G3QQV4 G3QQV4 SAP30 PTHR13286:SF7 SAP30 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000001899.3|UniProtKB=G3QHN5 G3QHN5 LOC101129851 PTHR23070:SF255 BCS1 AAA-TYPE ATPASE MITOCHONDRIAL CHAPERONE BCS1 cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;mitochondrial respiratory chain complex assembly#GO:0033108;protein insertion into membrane#GO:0051205;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000004946.3|UniProtKB=A0A2I2YVA4 A0A2I2YVA4 TACC2 PTHR13924:SF11 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 2 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;binding#GO:0005488 system development#GO:0048731;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;establishment of organelle localization#GO:0051656;cytoplasmic microtubule organization#GO:0031122;cell differentiation#GO:0030154;cell cycle process#GO:0022402;nuclear migration#GO:0007097;cellular component organization#GO:0016043;cell cycle#GO:0007049;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;spindle organization#GO:0007051;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996 spindle pole#GO:0000922;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000027003.2|UniProtKB=G3RQZ4 G3RQZ4 MRGPRD PTHR11334:SF57 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER D cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014610.3|UniProtKB=G3RF91 G3RF91 PTHR21561:SF12 INO80 COMPLEX SUBUNIT B INO80 COMPLEX SUBUNIT B chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011 GORGO|Gene=TAS2R31|UniProtKB=Q645Z6 Q645Z6 TAS2R31 PTHR11394:SF129 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 31 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008328.3|UniProtKB=G3QZ39 G3QZ39 TMEM101 PTHR31034:SF2 TRANSMEMBRANE PROTEIN 101 TRANSMEMBRANE PROTEIN 101 GORGO|Ensembl=ENSGGOG00000014166.3|UniProtKB=A0A2I2YSI6 A0A2I2YSI6 ATXN3 PTHR14159:SF0 ATAXIN-3-RELATED ATAXIN-3-RELATED catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;regulation of ERAD pathway#GO:1904292;primary metabolic process#GO:0044238;regulation of response to endoplasmic reticulum stress#GO:1905897;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of TORC1 signaling#GO:1904262 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008639.3|UniProtKB=G3QZX2 G3QZX2 FNDC11 PTHR14537:SF0 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 11 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 11 GORGO|Ensembl=ENSGGOG00000000423.3|UniProtKB=G3QDU0 G3QDU0 DLK1 PTHR24052:SF11 DELTA-RELATED PROTEIN DELTA HOMOLOG 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 GORGO|Ensembl=ENSGGOG00000008866.3|UniProtKB=G3R0I0 G3R0I0 NFYB PTHR11064:SF205 CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000006355.3|UniProtKB=G3QU29 G3QU29 ZNF333 PTHR24381:SF76 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 891 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000043034.1|UniProtKB=G3RKW9 G3RKW9 ZNF579 PTHR24383:SF14 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 579 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010569.3|UniProtKB=G3R4V5 G3R4V5 POGZ PTHR24403:SF59 ZINC FINGER PROTEIN POGO TRANSPOSABLE ELEMENT WITH ZNF DOMAIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015687.3|UniProtKB=G3RI20 G3RI20 PTHR46770:SF1 HOMEOBOX PROTEIN ORTHOPEDIA HOMEOBOX PROTEIN ORTHOPEDIA nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;system development#GO:0048731;neurogenesis#GO:0022008;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000000122.3|UniProtKB=G3QD18 G3QD18 PTHR10559:SF14 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR TRANSCOBALAMIN-2 binding#GO:0005488;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906 establishment of localization#GO:0051234;vitamin transport#GO:0051180;localization#GO:0051179;nitrogen compound transport#GO:0071705;transport#GO:0006810 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008298.3|UniProtKB=G3SDN6 G3SDN6 HDGF PTHR12550:SF41 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000003560.3|UniProtKB=G3QLX4 G3QLX4 TOMM34 PTHR45984:SF2 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM34 protein binding#GO:0005515;binding#GO:0005488;heat shock protein binding#GO:0031072 intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000005613.3|UniProtKB=G3QS75 G3QS75 POLD1 PTHR10322:SF23 DNA POLYMERASE CATALYTIC SUBUNIT DNA POLYMERASE DELTA CATALYTIC SUBUNIT exonuclease activity#GO:0004527;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;DNA exonuclease activity#GO:0004529;transferase activity#GO:0016740;3'-5' exonuclease activity#GO:0008408;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base-excision repair#GO:0006284 replisome#GO:0030894;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 GORGO|Ensembl=ENSGGOG00000016427.3|UniProtKB=G3RJX7 G3RJX7 ZSCAN32 PTHR23226:SF209 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 32 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008424.3|UniProtKB=G3QZC6 G3QZC6 TRMT10A PTHR13563:SF20 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG A binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA binding#GO:0000049;RNA binding#GO:0003723 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007565.3|UniProtKB=G3S3V0 G3S3V0 CLDND1 PTHR14347:SF3 CLAUDIN DOMAIN-CONTAINING PROTEIN 1 CLAUDIN DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000017166.3|UniProtKB=G3SCX7 G3SCX7 GAS6 PTHR24040:SF14 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN GROWTH ARREST-SPECIFIC PROTEIN 6 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000011229.3|UniProtKB=G3R6K5 G3R6K5 ABCA7 PTHR19229:SF49 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA7 cargo receptor activity#GO:0038024;primary active transmembrane transporter activity#GO:0015399;signaling receptor activity#GO:0038023;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;molecular transducer activity#GO:0060089;intramembrane lipid carrier activity#GO:0140303;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;phosphatidylcholine intramembrane carrier activity#GO:0008525;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane signaling receptor activity#GO:0004888 lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;sterol transport#GO:0015918;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cholesterol efflux#GO:0033344;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;phospholipid transport#GO:0015914 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000002687.3|UniProtKB=G3QJP4 G3QJP4 CPLX3 PTHR16705:SF5 COMPLEXIN COMPLEXIN-3 SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515 secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of signaling#GO:0023051;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;regulation of transport#GO:0051049;exocytosis#GO:0006887;regulation of localization#GO:0032879;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055;neurotransmitter transport#GO:0006836;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269 membrane protein complex#GO:0098796;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection terminus#GO:0044306;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;synapse#GO:0045202;axon#GO:0030424;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;presynapse#GO:0098793;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000026127.2|UniProtKB=G3S7Q4 G3S7Q4 PTHR11786:SF8 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 1 N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000012116.3|UniProtKB=G3R8V1 G3R8V1 ATP4B PTHR11523:SF11 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 monoatomic ion transport#GO:0006811;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000006046.3|UniProtKB=A0A2I2ZPJ1 A0A2I2ZPJ1 WDR20 PTHR14107:SF5 WD REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 20 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134 biological regulation#GO:0065007;negative regulation of protein catabolic process#GO:0042177;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of catabolic process#GO:0009894;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of cellular process#GO:0048523;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000007634.3|UniProtKB=G3QXC9 G3QXC9 GGA3 PTHR45905:SF3 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA3 enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;small GTPase binding#GO:0031267 vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;cellular process#GO:0009987;macromolecule localization#GO:0033036;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization within membrane#GO:0051668 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791 GORGO|Ensembl=ENSGGOG00000006782.3|UniProtKB=G3QV70 G3QV70 SCML4 PTHR12247:SF85 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 4 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000042907.1|UniProtKB=G3SF10 G3SF10 PTHR23299:SF47 METALLOTHIONEIN METALLOTHIONEIN ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 intracellular monoatomic ion homeostasis#GO:0006873;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;homeostatic process#GO:0042592;cellular response to chemical stimulus#GO:0070887;inorganic ion homeostasis#GO:0098771;detoxification of inorganic compound#GO:0061687;monoatomic ion homeostasis#GO:0050801;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;detoxification#GO:0098754;response to cadmium ion#GO:0046686;response to metal ion#GO:0010038;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008174.3|UniProtKB=G3QYQ6 G3QYQ6 FES PTHR24418:SF197 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FES_FPS signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;chemotaxis#GO:0006935;cell adhesion#GO:0007155;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;locomotion#GO:0040011;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;taxis#GO:0042330;response to chemical#GO:0042221;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 Axon guidance mediated by semaphorins#P00007>Fes#P00332 GORGO|Ensembl=ENSGGOG00000009074.3|UniProtKB=G3R121 G3R121 MMP11 PTHR10201:SF20 MATRIX METALLOPROTEINASE STROMELYSIN-3 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000002123.3|UniProtKB=G3QI87 G3QI87 OSGEP PTHR11735:SF14 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000027722.2|UniProtKB=G3RMF9 G3RMF9 FTH1 PTHR11431:SF37 FERRITIN FERRITIN HEAVY CHAIN iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;iron ion transport#GO:0006826;transport#GO:0006810;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000013245.3|UniProtKB=G3RBQ8 G3RBQ8 IMPDH PTHR11911:SF121 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 GORGO|Ensembl=ENSGGOG00000011330.3|UniProtKB=G3R6S9 G3R6S9 PTHR24418:SF23 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRMS catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular developmental process#GO:0048869;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 GORGO|Ensembl=ENSGGOG00000023236.2|UniProtKB=G3RTR0 G3RTR0 PALM3 PTHR47528:SF1 PARALEMMIN-3 PARALEMMIN-3 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to other organism#GO:0051707;negative regulation of response to stimulus#GO:0048585;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;response to external biotic stimulus#GO:0043207;negative regulation of response to cytokine stimulus#GO:0060761;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to bacterium#GO:0009617;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;response to lipid#GO:0033993;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;regulation of response to cytokine stimulus#GO:0060759;regulation of cytokine-mediated signaling pathway#GO:0001959;response to lipopolysaccharide#GO:0032496;negative regulation of cytokine-mediated signaling pathway#GO:0001960;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057 GORGO|Ensembl=ENSGGOG00000000470.3|UniProtKB=G3QDY1 G3QDY1 LRRC40 PTHR45752:SF160 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 40 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004482.3|UniProtKB=G3QPA4 G3QPA4 NUDT18 PTHR22769:SF56 MUTT/NUDIX HYDROLASE 8-OXO-DGDP PHOSPHATASE NUDT18 nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000004084.3|UniProtKB=G3QN95 G3QN95 MCM9 PTHR11630:SF48 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM9 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000000313.3|UniProtKB=A0A2I2Y8F6 A0A2I2Y8F6 PTHR24338:SF13 HOMEOBOX PROTEIN MSX HOMEOBOX DOMAIN-CONTAINING PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000007648.3|UniProtKB=G3RMC6 G3RMC6 TOPBP1 PTHR13561:SF20 DNA REPLICATION REGULATOR DPB11-RELATED DNA TOPOISOMERASE 2-BINDING PROTEIN 1 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000034980.2|UniProtKB=G3SKS2 G3SKS2 L3MBTL1 PTHR12247:SF69 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000014386.3|UniProtKB=G3REN9 G3REN9 PANX2 PTHR15759:SF7 PANNEXIN PANNEXIN-2 channel activity#GO:0015267;wide pore channel activity#GO:0022829;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of biological process#GO:0050789;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012588.3|UniProtKB=A0A2I2ZVQ1 A0A2I2ZVQ1 ASB1 PTHR24173:SF27 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 1 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003691.3|UniProtKB=A0A2I2ZWI0 A0A2I2ZWI0 METAP1D PTHR43330:SF28 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1D, MITOCHONDRIAL aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000011827.3|UniProtKB=G3R846 G3R846 INTS13 PTHR12955:SF1 SARCOMA ANTIGEN NY-SAR-95-RELATED INTEGRATOR COMPLEX SUBUNIT 13 localization#GO:0051179;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;centrosome localization#GO:0051642;regulation of cellular process#GO:0050794;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;integrator complex#GO:0032039;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000026311.2|UniProtKB=A0A2I2Z410 A0A2I2Z410 RUFY3 PTHR45956:SF1 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN PROTEIN RUFY3 regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344 axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;cell body#GO:0044297;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013840.3|UniProtKB=G3RDA4 G3RDA4 CNGA1 PTHR45638:SF9 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-1 guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;gated channel activity#GO:0022836;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;purine ribonucleotide binding#GO:0032555;monoatomic ion channel activity#GO:0005216;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;channel activity#GO:0015267;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;transport#GO:0006810;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 ion channel#PC00133;ligand-gated ion channel#PC00141 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 GORGO|Ensembl=ENSGGOG00000001963.3|UniProtKB=G3QHU9 G3QHU9 SPNS1 PTHR23505:SF13 SPINSTER PROTEIN SPINSTER HOMOLOG 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 carbohydrate derivative transport#GO:1901264;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003425.3|UniProtKB=G3SF17 G3SF17 UPP2 PTHR43691:SF8 URIDINE PHOSPHORYLASE URIDINE PHOSPHORYLASE 2 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;nucleoside catabolic process#GO:0009164;nucleobase-containing compound metabolic process#GO:0006139;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 GORGO|Ensembl=ENSGGOG00000009579.3|UniProtKB=G3R2C2 G3R2C2 PIK3CB PTHR10048:SF33 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;phosphatidylinositol phosphate biosynthetic process#GO:0046854;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;cell motility#GO:0048870;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622 kinase#PC00137 Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;Ras Pathway#P04393>PI3K#P04567;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Interleukin signaling pathway#P00036>PI3K#P00990;p53 pathway feedback loops 2#P04398>PI3K#P04661;Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;FGF signaling pathway#P00021>PI3K#P00640;B cell activation#P00010>PI3K#P00391;CCKR signaling map#P06959>p110#P07020;T cell activation#P00053>PI3K#P01322;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;PI3 kinase pathway#P00048>P110ACT#P01177;VEGF signaling pathway#P00056>PI3K#P01413;PI3 kinase pathway#P00048>p110#P01192 GORGO|Ensembl=ENSGGOG00000023867.2|UniProtKB=G3SJZ5 G3SJZ5 PTHR20981:SF8 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016213.3|UniProtKB=G3RJD2 G3RJD2 NTNG1 PTHR10574:SF28 NETRIN/LAMININ-RELATED NETRIN-G1 cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 GORGO|Ensembl=ENSGGOG00000016180.3|UniProtKB=G3RJA3 G3RJA3 ANGPTL6 PTHR19143:SF209 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 6 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000012254.3|UniProtKB=G3SBQ1 G3SBQ1 LOC101136923 PTHR26453:SF204 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2M3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000036694.1|UniProtKB=A0A2I2YM70 A0A2I2YM70 SNN PTHR28564:SF1 STANNIN STANNIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005113.3|UniProtKB=A0A2I2Z434 A0A2I2Z434 TP63 PTHR11447:SF8 CELLULAR TUMOR ANTIGEN P53 TUMOR PROTEIN 63 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;intrinsic apoptotic signaling pathway#GO:0097193;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of apoptotic process#GO:0042981;positive regulation of macromolecule metabolic process#GO:0010604;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;regulation of gene expression#GO:0010468;DNA damage response#GO:0006974;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;P53-like transcription factor#PC00253 Huntington disease#P00029>p53#P00797;p53 pathway#P00059>p53#P01485;p53 pathway feedback loops 2#P04398>p53#P04668;P53 pathway feedback loops 1#P04392>p73DeltaN#G04685;P53 pathway feedback loops 1#P04392>p73DeltaN#P04537;p53 pathway#P00059>p53#G04702;P53 pathway feedback loops 1#P04392>p53#P04539;p53 pathway by glucose deprivation#P04397>p53#P04640 GORGO|Ensembl=ENSGGOG00000014447.3|UniProtKB=G3SCJ9 G3SCJ9 LOC101126065 PTHR24404:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 835 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012173.3|UniProtKB=G3R919 G3R919 CUX2 PTHR14043:SF5 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT-LIKE 2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000007727.3|UniProtKB=G3QXL3 G3QXL3 SNTB2 PTHR10554:SF8 SYNTROPHIN BETA-2-SYNTROPHIN cell junction#GO:0030054;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002984.3|UniProtKB=G3QKG2 G3QKG2 SUGP1 PTHR23340:SF3 ARGININE/SERINE RICH SPLICING FACTOR SF4/14 SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000004352.3|UniProtKB=G3SJH6 G3SJH6 C8G PTHR47304:SF1 COMPLEMENT COMPONENT C8 GAMMA CHAIN COMPLEMENT COMPONENT C8 GAMMA CHAIN regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of biological process#GO:0050789;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;humoral immune response#GO:0006959;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;positive regulation of biological process#GO:0048518;immune response#GO:0006955;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;complement activation#GO:0006956;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;defense response to other organism#GO:0098542 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 complement component#PC00078 GORGO|Ensembl=ENSGGOG00000014107.3|UniProtKB=G3RE05 G3RE05 QSOX2 PTHR22897:SF7 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE 2 catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 protein folding#GO:0006457;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;extracellular structure organization#GO:0043062;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;protein maturation#GO:0051604;extracellular matrix assembly#GO:0085029;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000023563.2|UniProtKB=G3S8V0 G3S8V0 SPINK8 PTHR21312:SF37 SERINE PROTEASE INHIBITOR SERINE PROTEASE INHIBITOR KAZAL-TYPE 8 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000016852.3|UniProtKB=A0A2I2Y228 A0A2I2Y228 PIAS1 PTHR10782:SF11 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS1 SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;negative regulation of cellular process#GO:0048523;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;metabolic process#GO:0008152;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;protein sumoylation#GO:0016925;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 GORGO|Ensembl=ENSGGOG00000001841.3|UniProtKB=G3QHI6 G3QHI6 PKD2L1 PTHR10877:SF196 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2-LIKE PROTEIN 1 metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;cytoskeletal protein binding#GO:0008092;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;gated channel activity#GO:0022836;binding#GO:0005488;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium-activated potassium channel activity#GO:0015269;monoatomic ion-gated channel activity#GO:0022839;cation binding#GO:0043169;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;ion binding#GO:0043167;small molecule binding#GO:0036094 monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;response to mechanical stimulus#GO:0009612;cellular process#GO:0009987;detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;establishment of localization#GO:0051234;transport#GO:0006810;detection of mechanical stimulus#GO:0050982;metal ion transport#GO:0030001;response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000010974.3|UniProtKB=G3RP65 G3RP65 FBXO28 PTHR13252:SF9 F-BOX ONLY PROTEIN 28 F-BOX ONLY PROTEIN 28 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 GORGO|Ensembl=ENSGGOG00000009963.3|UniProtKB=G3R3A3 G3R3A3 LY6G5C PTHR14909:SF6 LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G5C LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G5C cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000013548.3|UniProtKB=G3RCJ4 G3RCJ4 FKBP15 PTHR44927:SF1 FK506-BINDING PROTEIN 15 FK506-BINDING PROTEIN 15 site of polarized growth#GO:0030427;axon#GO:0030424;growth cone#GO:0030426;cell projection#GO:0042995;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 GORGO|Ensembl=ENSGGOG00000009263.3|UniProtKB=G3R1J3 G3R1J3 PTPRF PTHR19134:SF203 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;synapse organization#GO:0050808;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;synaptic membrane adhesion#GO:0099560;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008516.3|UniProtKB=G3QZK9 G3QZK9 VXN PTHR31520:SF1 VEXIN VEXIN multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;animal gross anatomical part developmental process#GO:0160108;neuron differentiation#GO:0030182;generation of neurons#GO:0048699;developmental process#GO:0032502;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000015725.3|UniProtKB=G3RI52 G3RI52 ZNF395 PTHR13006:SF6 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 ZINC FINGER PROTEIN 395 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000039217.1|UniProtKB=G3R1E2 G3R1E2 ARPC1A PTHR10709:SF11 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1A cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 GORGO|Ensembl=ENSGGOG00000013414.3|UniProtKB=G3QIL2 G3QIL2 LOC101141937 PTHR14199:SF29 NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 6-LIKE PROTEIN NBPF FAMILY MEMBER NBPF4-RELATED GORGO|Ensembl=ENSGGOG00000007385.3|UniProtKB=G3QWR4 G3QWR4 VIPR2 PTHR45620:SF22 PDF RECEPTOR-LIKE PROTEIN-RELATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000022869.2|UniProtKB=G3SCA7 G3SCA7 PROP1 PTHR47409:SF1 HOMEOBOX PROTEIN PROPHET OF PIT-1 HOMEOBOX PROTEIN PROPHET OF PIT-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000000054.3|UniProtKB=A0A2I2Y5P3 A0A2I2Y5P3 PTHR10902:SF19 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;translation#GO:0006412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000024271.2|UniProtKB=G3SFM2 G3SFM2 LOC101146371 PTHR22932:SF3 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE PROSTAGLANDIN E SYNTHASE 3 isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;catalytic activity#GO:0003824;protein binding#GO:0005515;Hsp90 protein binding#GO:0051879;binding#GO:0005488 cellular component assembly#GO:0022607;telomere maintenance via telomere lengthening#GO:0010833;icosanoid metabolic process#GO:0006690;telomere maintenance via telomerase#GO:0007004;gene expression#GO:0010467;protein maturation#GO:0051604;icosanoid biosynthetic process#GO:0046456;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;unsaturated fatty acid metabolic process#GO:0033559;small molecule metabolic process#GO:0044281;ribonucleoprotein complex biogenesis#GO:0022613;protein folding#GO:0006457;monocarboxylic acid metabolic process#GO:0032787;cellular component organization#GO:0016043;carboxylic acid metabolic process#GO:0019752;protein-containing complex assembly#GO:0065003;oxoacid metabolic process#GO:0043436;nucleic acid biosynthetic process#GO:0141187;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;unsaturated fatty acid biosynthetic process#GO:0006636;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;monocarboxylic acid biosynthetic process#GO:0072330;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;RNA-templated DNA biosynthetic process#GO:0006278;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;telomere organization#GO:0032200;chaperone-mediated protein complex assembly#GO:0051131;prostaglandin metabolic process#GO:0006693 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000037353.1|UniProtKB=A0A2I2YDG6 A0A2I2YDG6 PTHR10709:SF18 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1A cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000008230.3|UniProtKB=G3QYV7 G3QYV7 C6 PTHR45742:SF4 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C6 regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;humoral immune response#GO:0006959;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;extracellular region#GO:0005576 complement component#PC00078 GORGO|Ensembl=ENSGGOG00000013428.3|UniProtKB=G3RC82 G3RC82 GBP4 PTHR10751:SF142 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 4 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein#PC00020;heterotrimeric G-protein#PC00117 GORGO|Ensembl=ENSGGOG00000037632.1|UniProtKB=A0A2I2ZSF1 A0A2I2ZSF1 C20H19orf38 PTHR36859:SF1 PROTEIN HIDE1 PROTEIN HIDE1 GORGO|Ensembl=ENSGGOG00000042032.1|UniProtKB=A0A2I2YPW2 A0A2I2YPW2 GPX6 PTHR11592:SF15 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 6 catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to oxidative stress#GO:0034599;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 oxidoreductase#PC00176;peroxidase#PC00180 GORGO|Ensembl=ENSGGOG00000038310.1|UniProtKB=A0A2I2ZYY3 A0A2I2ZYY3 PPP1R2C PTHR12398:SF29 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE INHIBITOR 2 FAMILY MEMBER C phosphatase regulator activity#GO:0019208;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 phosphatase inhibitor#PC00183 GORGO|Ensembl=ENSGGOG00000003574.3|UniProtKB=A0A2I2YVQ7 A0A2I2YVQ7 EMCN PTHR15869:SF0 ENDOMUCIN-RELATED ENDOMUCIN negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of cell adhesion#GO:0007162;negative regulation of leukocyte cell-cell adhesion#GO:1903038;biological regulation#GO:0065007 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 GORGO|Ensembl=ENSGGOG00000023204.2|UniProtKB=G3SBF6 G3SBF6 SLX4IP PTHR28557:SF1 PROTEIN SLX4IP PROTEIN SLX4IP GORGO|Ensembl=ENSGGOG00000004450.3|UniProtKB=G3QP77 G3QP77 TGFB1I1 PTHR24216:SF27 PAXILLIN-RELATED TRANSFORMING GROWTH FACTOR BETA-1-INDUCED TRANSCRIPT 1 PROTEIN transcription coactivator activity#GO:0003713;protein sequestering activity#GO:0140311;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular sequestering activity#GO:0140313 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418 GORGO|Ensembl=ENSGGOG00000043387.1|UniProtKB=G3S393 G3S393 DDX10 PTHR24031:SF775 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX10-RELATED gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000037536.1|UniProtKB=A0A2I2ZBA4 A0A2I2ZBA4 PTHR48013:SF16 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000006634.3|UniProtKB=G3QUT4 G3QUT4 ALDH5A1 PTHR43353:SF14 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481;Aminobutyrate degradation#P02726>Succinate semi-aldehyde dehydrogenase#P02824 GORGO|Ensembl=ENSGGOG00000007903.3|UniProtKB=G3QY06 G3QY06 SMDT1 PTHR33904:SF1 ESSENTIAL MCU REGULATOR, MITOCHONDRIAL ESSENTIAL MCU REGULATOR, MITOCHONDRIAL monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 mitochondrial protein-containing complex#GO:0098798;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;transporter complex#GO:1990351;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011435.3|UniProtKB=G3R731 G3R731 CTR9 PTHR14027:SF2 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000011529.3|UniProtKB=G3S012 G3S012 CDH15 PTHR24027:SF300 CADHERIN-23 CADHERIN-15 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;cell migration#GO:0016477;cell motility#GO:0048870 extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000004575.3|UniProtKB=G3RMT4 G3RMT4 FCN1 PTHR19143:SF377 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-1 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000002500.3|UniProtKB=G3QJ78 G3QJ78 MRPS12 PTHR11652:SF1 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 ribosome#GO:0005840;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000015978.3|UniProtKB=G3RIR8 G3RIR8 PTHR45827:SF3 SORTING NEXIN SORTING NEXIN-33 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168 import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;membrane invagination#GO:0010324;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;plasma membrane organization#GO:0007009;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;endocytosis#GO:0006897;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027109.2|UniProtKB=G3RZT2 G3RZT2 PTHR23267:SF511 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-9 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000037097.1|UniProtKB=A0A2I2YVD9 A0A2I2YVD9 PTHR13215:SF0 RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004716.3|UniProtKB=G3QPW2 G3QPW2 FUOM PTHR31690:SF4 FUCOSE MUTAROTASE FUCOSE MUTAROTASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;isomerase activity#GO:0016853;monosaccharide binding#GO:0048029;carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488 cellular process#GO:0009987;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281 GORGO|Ensembl=ENSGGOG00000010221.3|UniProtKB=G3R409 G3R409 COL9A1 PTHR24023:SF918 COLLAGEN ALPHA COLLAGEN ALPHA-1(IX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000000015.3|UniProtKB=G3QCS0 G3QCS0 LOC101133989 PTHR23105:SF129 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA processing#GO:0016180;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006164.3|UniProtKB=G3QL95 G3QL95 LOC101154124 PTHR48615:SF8 LATE CORNIFIED ENVELOPE PROTEIN 1C LATE CORNIFIED ENVELOPE PROTEIN 1C GORGO|Ensembl=ENSGGOG00000013602.3|UniProtKB=G3RCP0 G3RCP0 HSF1 PTHR10015:SF274 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000023687.2|UniProtKB=G3RXS2 G3RXS2 RBMX2 PTHR45880:SF4 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525 GORGO|Ensembl=ENSGGOG00000009252.3|UniProtKB=A0A2I2ZXF3 A0A2I2ZXF3 PTHR12120:SF1 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000384.3|UniProtKB=G3QDQ2 G3QDQ2 DCAF15 PTHR28541:SF1 DDB1- AND CUL4-ASSOCIATED FACTOR 15 DDB1- AND CUL4-ASSOCIATED FACTOR 15 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000000577.3|UniProtKB=G3QE80 G3QE80 ANKRD13B PTHR12447:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;biological regulation#GO:0065007 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009011.3|UniProtKB=G3R0X0 G3R0X0 TXK PTHR24418:SF247 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE TXK kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 GORGO|Ensembl=ENSGGOG00000022739.2|UniProtKB=G3S4R8 G3S4R8 PTHR45616:SF44 GATA-TYPE DOMAIN-CONTAINING PROTEIN IF ROD DOMAIN-CONTAINING PROTEIN cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;muscle cell development#GO:0055001;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108 supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 GORGO|Ensembl=ENSGGOG00000005193.3|UniProtKB=G3S667 G3S667 TSC22D3 PTHR12348:SF24 TSC22 TSC22 DOMAIN FAMILY PROTEIN 3 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000040977.1|UniProtKB=A0A2I2ZQH6 A0A2I2ZQH6 LOC101126237 PTHR11961:SF6 CYTOCHROME C CYTOCHROME C, TESTIS-SPECIFIC aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967 Apoptosis signaling pathway#P00006>Cytochrome C#P00322 GORGO|Ensembl=ENSGGOG00000006094.3|UniProtKB=G3RVJ2 G3RVJ2 BACH1 PTHR46105:SF1 AGAP004733-PA TRANSCRIPTION REGULATOR PROTEIN BACH1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015257.3|UniProtKB=G3RGX7 G3RGX7 PADI6 PTHR10837:SF4 PEPTIDYLARGININE DEIMINASE INACTIVE PROTEIN-ARGININE DEIMINASE TYPE-6 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004941.3|UniProtKB=G3QQH5 G3QQH5 HJV PTHR31428:SF3 RGM DOMAIN FAMILY MEMBER DRAG-1 HEMOJUVELIN coreceptor activity#GO:0015026;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235 GORGO|Ensembl=ENSGGOG00000014532.2|UniProtKB=A0A2I2ZEN8 A0A2I2ZEN8 ACTBL2 PTHR11937:SF168 ACTIN BETA-ACTIN-LIKE PROTEIN 2 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell junction#GO:0030054;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Cadherin signaling pathway#P00012>F-actin#P00470;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 GORGO|Ensembl=ENSGGOG00000005940.3|UniProtKB=G3QT06 G3QT06 CALY PTHR28546:SF1 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURON-SPECIFIC VESICULAR PROTEIN CALCYON intracellular protein localization#GO:0008104;regulation of biological quality#GO:0065008;protein transport#GO:0015031;localization#GO:0051179;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;metabolic process#GO:0008152;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;biological regulation#GO:0065007;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 cell junction#GO:0030054;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;plasma membrane region#GO:0098590;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000009444.3|UniProtKB=G3R1Z1 G3R1Z1 TREML2 PTHR16423:SF3 TREM-LIKE TRANSCRIPT PROTEIN TREM-LIKE TRANSCRIPT 2 PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cell activation#GO:0001775;immune system process#GO:0002376;leukocyte activation#GO:0045321;T cell activation#GO:0042110 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 GORGO|Ensembl=ENSGGOG00000015372.3|UniProtKB=G3RH96 G3RH96 ABCA6 PTHR19229:SF13 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 6 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234;transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000004550.3|UniProtKB=G3QPH2 G3QPH2 RIC1 PTHR22746:SF11 RAB6A-GEF COMPLEX PARTNER PROTEIN 1 GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;intracellular protein localization#GO:0008104;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;protein localization to cell junction#GO:1902414;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;neuron projection development#GO:0031175;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;endosomal transport#GO:0016197;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cytosolic transport#GO:0016482;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular localization#GO:0051641;axonogenesis#GO:0007409;protein transport#GO:0015031;neuron development#GO:0048666 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000012003.3|UniProtKB=G3R8J5 G3R8J5 TEX44 PTHR37365:SF1 TESTIS-EXPRESSED PROTEIN 44 TESTIS-EXPRESSED PROTEIN 44 GORGO|Ensembl=ENSGGOG00000007034.3|UniProtKB=G3SJK8 G3SJK8 SYNGR3 PTHR10838:SF8 SYNAPTOGYRIN SYNAPTOGYRIN-3 transport#GO:0006810;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular process#GO:0009987;synaptic vesicle membrane organization#GO:0048499;cellular component organization#GO:0016043;export from cell#GO:0140352;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192 organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell junction#GO:0030054;neuromuscular junction#GO:0031594 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000038577.1|UniProtKB=A0A2I2ZKQ6 A0A2I2ZKQ6 PTPRN2 PTHR46106:SF5 IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE N2 peptide hormone secretion#GO:0030072;secretion#GO:0046903;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;peptide secretion#GO:0002790;signal release#GO:0023061;homeostatic process#GO:0042592;protein localization to extracellular region#GO:0071692;cellular response to stimulus#GO:0051716;cellular homeostasis#GO:0019725;establishment of protein localization to extracellular region#GO:0035592;intracellular chemical homeostasis#GO:0055082;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;response to glucose#GO:0009749;insulin secretion#GO:0030073;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;peptide transport#GO:0015833;regulation of biological quality#GO:0065008;hormone secretion#GO:0046879;protein transport#GO:0015031;response to carbohydrate#GO:0009743;intracellular glucose homeostasis#GO:0001678;secretion by cell#GO:0032940;cellular localization#GO:0051641;protein secretion#GO:0009306;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to monosaccharide#GO:0034284;signaling#GO:0023052;export from cell#GO:0140352;response to stimulus#GO:0050896;regulation of hormone levels#GO:0010817;carbohydrate homeostasis#GO:0033500;regulation of biological process#GO:0050789;response to hexose#GO:0009746;regulation of localization#GO:0032879;regulation of transport#GO:0051049;glucose homeostasis#GO:0042593;hormone transport#GO:0009914;chemical homeostasis#GO:0048878;cellular response to glucose stimulus#GO:0071333;response to chemical#GO:0042221;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular response to oxygen-containing compound#GO:1901701 vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cell junction#GO:0030054 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000038751.1|UniProtKB=Q646A1 Q646A1 TAS2R50 PTHR11394:SF43 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 50 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000932.3|UniProtKB=G3QF55 G3QF55 SPACDR PTHR39221:SF1 CHROMOSOME 7 OPEN READING FRAME 61 SPERM ACROSOME DEVELOPMENTAL REGULATOR GORGO|Ensembl=ENSGGOG00000013117.3|UniProtKB=G3RBE5 G3RBE5 PPARG PTHR24082:SF488 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of lipid metabolic process#GO:0019216;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to chemical stimulus#GO:0070887;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;hormone-mediated signaling pathway#GO:0009755;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C4 zinc finger nuclear receptor#PC00169 CCKR signaling map#P06959>PPARgamma#P07060;Gonadotropin-releasing hormone receptor pathway#P06664>PPARalpha/gamma#P06744;Gonadotropin-releasing hormone receptor pathway#P06664>PPARgamma#P06721 GORGO|Ensembl=ENSGGOG00000002803.3|UniProtKB=G3SHF8 G3SHF8 NYAP1 PTHR22633:SF2 NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2-RELATED NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 1 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system development#GO:0048731;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;cellular developmental process#GO:0048869 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013109.3|UniProtKB=G3RBD8 G3RBD8 ATG10 PTHR14957:SF1 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10 ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;Atg12 transferase activity#GO:0019777;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;Atg12 conjugating enzyme activity#GO:0061651 protein modification by small protein conjugation or removal#GO:0070647;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular component organization#GO:0016043;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;post-translational protein modification#GO:0043687;macroautophagy#GO:0016236;cellular component assembly#GO:0022607 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000001667.3|UniProtKB=G3QH26 G3QH26 SH3BP5 PTHR19423:SF1 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5 enzyme inhibitor activity#GO:0004857;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;kinase inhibitor activity#GO:0019210;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003083.3|UniProtKB=G3QKQ3 G3QKQ3 SEMA4D PTHR11036:SF18 SEMAPHORIN SEMAPHORIN-4D receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;taxis#GO:0042330;response to chemical#GO:0042221;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 Axon guidance mediated by semaphorins#P00007>Sema4D#P00329 GORGO|Ensembl=ENSGGOG00000011690.3|UniProtKB=A0A2I2Z3S8 A0A2I2Z3S8 TCOF1 PTHR20787:SF10 TREACLE TREACLE PROTEIN protein binding#GO:0005515;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase I#GO:0006360;rRNA transcription#GO:0009303;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015206.3|UniProtKB=G3RGS8 G3RGS8 KLF10 PTHR23235:SF64 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 10 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000043832.1|UniProtKB=A0A2I2ZZ07 A0A2I2ZZ07 ZG16 PTHR33589:SF4 OS11G0524900 PROTEIN ZYMOGEN GRANULE MEMBRANE PROTEIN 16 GORGO|Ensembl=ENSGGOG00000005435.3|UniProtKB=G3QRR0 G3QRR0 CIMAP2 PTHR34914:SF1 LYMPHOCYTE EXPANSION MOLECULE CILIARY MICROTUBULE-ASSOCIATED PROTEIN 2 GORGO|Ensembl=ENSGGOG00000001833.3|UniProtKB=G3QHH9 G3QHH9 RSF1 PTHR14296:SF16 REMODELING AND SPACING FACTOR 1 REMODELING AND SPACING FACTOR 1 histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular component assembly#GO:0022607;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002934.3|UniProtKB=A0A2I2Z234 A0A2I2Z234 ACVR1 PTHR23255:SF69 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1 transferase activity#GO:0016740;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;signaling receptor activity#GO:0038023;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;molecular transducer activity#GO:0060089 heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;cellular developmental process#GO:0048869;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;response to BMP#GO:0071772;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;dorsal/ventral pattern formation#GO:0009953;BMP signaling pathway#GO:0030509;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;pattern specification process#GO:0007389;response to transforming growth factor beta#GO:0071559 signaling receptor complex#GO:0043235;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 GORGO|Ensembl=ENSGGOG00000004910.3|UniProtKB=G3QQE5 G3QQE5 RNF170 PTHR22894:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF170 GORGO|Ensembl=ENSGGOG00000009358.3|UniProtKB=G3R1R6 G3R1R6 DCAF5 PTHR15574:SF43 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 5 regulation of lipid metabolic process#GO:0019216;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of lipid biosynthetic process#GO:0046890;regulation of cellular process#GO:0050794;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002571.3|UniProtKB=A0A2I2Z358 A0A2I2Z358 ODF2L PTHR23162:SF7 OUTER DENSE FIBER OF SPERM TAILS 2 PROTEIN BCAP regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cell projection assembly#GO:0060491;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344 microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000002983.3|UniProtKB=G3QKG0 G3QKG0 TM6SF2 PTHR14568:SF9 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 TRANSMEMBRANE 6 SUPERFAMILY MEMBER 2 chemical homeostasis#GO:0048878;regulation of lipid metabolic process#GO:0019216;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;lipid homeostasis#GO:0055088;regulation of metabolic process#GO:0019222;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 GORGO|Ensembl=ENSGGOG00000028599.2|UniProtKB=G3SJ70 G3SJ70 FAM185A PTHR34094:SF1 FAMILY NOT NAMED PROTEIN FAM185A GORGO|Ensembl=ENSGGOG00000005590.3|UniProtKB=G3QS48 G3QS48 S100PBP PTHR14455:SF0 ASKOPOS S100P-BINDING PROTEIN GORGO|Ensembl=ENSGGOG00000037241.1|UniProtKB=G3RTH8 G3RTH8 PTHR11636:SF42 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 1 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000006120.3|UniProtKB=G3QTH1 G3QTH1 FOXK2 PTHR45881:SF3 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED FORKHEAD BOX PROTEIN K2 GORGO|Ensembl=ENSGGOG00000007530.3|UniProtKB=G3QX42 G3QX42 BPI PTHR10504:SF84 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BACTERICIDAL PERMEABILITY-INCREASING PROTEIN lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 defense response to bacterium#GO:0042742;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;defense response to Gram-negative bacterium#GO:0050829;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;defense response to other organism#GO:0098542;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;regulation of macrophage activation#GO:0043030;defense response to symbiont#GO:0140546;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;cell communication#GO:0007154;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617;response to external biotic stimulus#GO:0043207;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;negative regulation of multicellular organismal process#GO:0051241;cellular response to biotic stimulus#GO:0071216;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of biosynthetic process#GO:0009889;negative regulation of cell activation#GO:0050866;innate immune response#GO:0045087;cellular response to molecule of bacterial origin#GO:0071219;negative regulation of cellular process#GO:0048523;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;response to other organism#GO:0051707;negative regulation of macromolecule metabolic process#GO:0010605;immune response#GO:0006955;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000013026.3|UniProtKB=G3RB71 G3RB71 PAK1IP1 PTHR44675:SF1 PAK1 INTERACTING PROTEIN 1 P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1 kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000014006.3|UniProtKB=G3RDQ1 G3RDQ1 VANGL2 PTHR20886:SF10 VANG-LIKE PROTEIN VANG-LIKE PROTEIN 2 animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;non-canonical Wnt signaling pathway#GO:0035567;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signaling#GO:0023052;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;morphogenesis of an epithelium#GO:0002009;signal transduction#GO:0007165;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000025654.2|UniProtKB=G3RPF1 G3RPF1 LOC101129103 PTHR23023:SF81 DIMETHYLANILINE MONOOXYGENASE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 6-RELATED monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000015107.3|UniProtKB=G3RGJ1 G3RGJ1 EMP3 PTHR10671:SF8 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 3 plasma membrane bounded cell projection assembly#GO:0120031;bleb assembly#GO:0032060;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000026693.2|UniProtKB=G3S7T0 G3S7T0 PTHR11524:SF13 60S RIBOSOMAL PROTEIN L7 RIBOSOMAL PROTEIN UL30-LIKE RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007765.3|UniProtKB=A0A2I2ZMV0 A0A2I2ZMV0 ARPIN PTHR31199:SF1 ARPIN ARPIN negative regulation of biological process#GO:0048519;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;negative regulation of cytoskeleton organization#GO:0051494;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523 GORGO|Ensembl=ENSGGOG00000008498.3|UniProtKB=G3QZJ2 G3QZJ2 KIAA1614 PTHR14102:SF12 PAR-6-RELATED CDNA SEQUENCE BC034090 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 centrosome cycle#GO:0007098;cellular process#GO:0009987;cell cycle process#GO:0022402;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;establishment or maintenance of cell polarity#GO:0007163;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cell-cell junction maintenance#GO:0045217 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;apical plasma membrane#GO:0016324;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;protein kinase complex#GO:1902911;apical part of cell#GO:0045177;transferase complex#GO:1990234 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000005810.3|UniProtKB=G3QSP6 G3QSP6 MYCBP PTHR13168:SF2 ASSOCIATE OF C-MYC AMY-1 C-MYC-BINDING PROTEIN transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 PDGF signaling pathway#P00047>c-Myc#P01172 GORGO|Ensembl=ENSGGOG00000010769.3|UniProtKB=G3R5D0 G3R5D0 EPHX3 PTHR43329:SF10 EPOXIDE HYDROLASE EPOXIDE HYDROLASE 3 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ether hydrolase activity#GO:0016803 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000007851.3|UniProtKB=G3QXW3 G3QXW3 CAPN6 PTHR10183:SF381 CALPAIN CALPAIN-6 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000023815.2|UniProtKB=G3SG71 G3SG71 STATH PTHR15057:SF3 STATHERIN STATHERIN response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response#GO:0006952;response to external stimulus#GO:0009605;cell killing#GO:0001906;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013566.3|UniProtKB=G3RCK6 G3RCK6 SRPK1 PTHR47634:SF4 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SRSF PROTEIN KINASE 1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;signal transduction#GO:0007165;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;signaling#GO:0023052;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;response to stimulus#GO:0050896;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000023793.2|UniProtKB=A0A2I2ZCG9 A0A2I2ZCG9 RPGR PTHR22872:SF9 BTK-BINDING PROTEIN-RELATED X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR GORGO|Ensembl=ENSGGOG00000000808.4|UniProtKB=G3QEU5 G3QEU5 SPOCK1 PTHR13866:SF17 SPARC OSTEONECTIN TESTICAN-1 metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cation binding#GO:0043169;binding#GO:0005488;peptidase inhibitor activity#GO:0030414;small molecule binding#GO:0036094;endopeptidase regulator activity#GO:0061135;ion binding#GO:0043167;calcium ion binding#GO:0005509;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000025131.2|UniProtKB=G3RUT2 G3RUT2 NCOA3 PTHR10684:SF3 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 3 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulator activity#GO:0140110;binding#GO:0005488 positive regulation of transcription by RNA polymerase II#GO:0045944;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to chemical stimulus#GO:0070887;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 Gonadotropin-releasing hormone receptor pathway#P06664>Ncoa3#P06719 GORGO|Ensembl=ENSGGOG00000008941.3|UniProtKB=G3R0Q3 G3R0Q3 ATP6V0A2 PTHR11629:SF22 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 2 protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;enzyme binding#GO:0019899;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;cellular component disassembly#GO:0022411;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;process utilizing autophagic mechanism#GO:0061919;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;monoatomic ion homeostasis#GO:0050801;autophagy#GO:0006914;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;monoatomic cation transport#GO:0006812;localization#GO:0051179;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;homeostatic process#GO:0042592;autophagosome maturation#GO:0097352;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;biological regulation#GO:0065007;macroautophagy#GO:0016236;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ATPase complex#GO:1904949;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000016462.3|UniProtKB=G3RK07 G3RK07 SRSF5 PTHR23147:SF237 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 5 nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000011175.3|UniProtKB=A0A2I2Y1T9 A0A2I2Y1T9 SRGAP3 PTHR14166:SF8 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 3 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;animal gross anatomical part developmental process#GO:0160108;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of cell motility#GO:2000145;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000010328.3|UniProtKB=G3R490 G3R490 MSI1 PTHR48032:SF3 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 RNA-BINDING PROTEIN MUSASHI HOMOLOG 1 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007611.4|UniProtKB=G3QXB5 G3QXB5 BRF1 PTHR11618:SF4 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 GORGO|Ensembl=ENSGGOG00000003021.3|UniProtKB=G3QKK1 G3QKK1 PTHR10183:SF302 CALPAIN CALPAIN-14 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000016459.3|UniProtKB=G3RK00 G3RK00 PTHR26450:SF355 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52J3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000024021.2|UniProtKB=G3RXA6 G3RXA6 CDC123 PTHR15323:SF6 D123 PROTEIN TRANSLATION INITIATION FACTOR EIF2 ASSEMBLY PROTEIN cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012201.3|UniProtKB=G3R929 G3R929 FKBP2 PTHR45779:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2 isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 TGF-beta signaling pathway#P00052>FKBP12#P01288 GORGO|Ensembl=ENSGGOG00000043307.1|UniProtKB=A0A2I2ZAS4 A0A2I2ZAS4 PTHR43986:SF6 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000007483.4|UniProtKB=G3QX08 G3QX08 TAF2 PTHR15137:SF9 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 GORGO|Ensembl=ENSGGOG00000001488.3|UniProtKB=G3QGL6 G3QGL6 LOC109029274 PTHR26453:SF286 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T33-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013895.3|UniProtKB=G3RSI2 G3RSI2 SRP68 PTHR12860:SF0 SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010792.3|UniProtKB=G3SGY6 G3SGY6 TCHP PTHR31183:SF2 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;programmed cell death#GO:0012501 intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000040552.1|UniProtKB=A0A2I2YNH5 A0A2I2YNH5 CTXND1 PTHR16736:SF5 CORTEXIN-1-RELATED CORTEXIN DOMAIN-CONTAINING 1 PROTEIN GORGO|Ensembl=ENSGGOG00000014300.3|UniProtKB=G3REF8 G3REF8 IL10 PTHR48482:SF5 INTERLEUKIN-19-RELATED INTERLEUKIN-10 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;negative regulation of defense response#GO:0031348;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;negative regulation of inflammatory response#GO:0050728;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;immune system process#GO:0002376;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;response to cytokine#GO:0034097 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Interleukin signaling pathway#P00036>Interleukin#P00970 GORGO|Ensembl=ENSGGOG00000027061.2|UniProtKB=G3SBZ2 G3SBZ2 VBP1 PTHR12409:SF0 PREFOLDIN SUBUNIT 3 PREFOLDIN SUBUNIT 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;protein folding#GO:0006457;protein metabolic process#GO:0019538;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000017163.3|UniProtKB=G3RLT9 G3RLT9 LOC101129437 PTHR47015:SF3 BPI FOLD-CONTAINING FAMILY A MEMBER 1 BPIFA4P PROTEIN-RELATED homeostatic process#GO:0042592;multicellular organismal-level homeostasis#GO:0048871;multicellular organismal process#GO:0032501;chemical homeostasis#GO:0048878 GORGO|Ensembl=ENSGGOG00000011328.3|UniProtKB=G3R6T0 G3R6T0 CABCOCO1 PTHR28457:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 CILIARY-ASSOCIATED CALCIUM-BINDING COILED-COIL PROTEIN 1 GORGO|Ensembl=ENSGGOG00000012229.3|UniProtKB=G3SJI4 G3SJI4 VSIG10 PTHR11640:SF157 NEPHRIN V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000001135.3|UniProtKB=G3QFP2 G3QFP2 PTHR24379:SF40 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 700 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000008236.3|UniProtKB=G3QYW4 G3QYW4 DPY19L1 PTHR31488:SF5 DPY-19-LIKE 1, LIKE (H. SAPIENS) PROTEIN C-MANNOSYL-TRANSFERASE DPY19L1 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000022273.2|UniProtKB=G3SFG5 G3SFG5 LRGUK PTHR23117:SF18 GUANYLATE KINASE-RELATED LEUCINE-RICH REPEAT AND GUANYLATE KINASE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cilium organization#GO:0044782;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;gamete generation#GO:0007276;small molecule metabolic process#GO:0044281;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;ribose phosphate biosynthetic process#GO:0046390;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;cell projection assembly#GO:0030031;organophosphate biosynthetic process#GO:0090407;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;nucleoside diphosphate metabolic process#GO:0009132;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;nucleoside phosphate metabolic process#GO:0006753;reproductive process#GO:0022414;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;nucleoside phosphate biosynthetic process#GO:1901293;plasma membrane bounded cell projection assembly#GO:0120031;purine ribonucleoside diphosphate metabolic process#GO:0009179;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669 kinase#PC00137;transferase#PC00220 GORGO|Gene=TAS2R39|UniProtKB=Q645Y7 Q645Y7 TAS2R39 PTHR11394:SF142 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 39 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000292.3|UniProtKB=A0A2I2ZRW5 A0A2I2ZRW5 LOC101153990 PTHR10814:SF31 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 4 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 GORGO|Ensembl=ENSGGOG00000000024.3|UniProtKB=G3QCS8 G3QCS8 PPM1N PTHR47992:SF59 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1N-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical Wnt signaling pathway#GO:0060828 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000036901.1|UniProtKB=A0A2I2YW34 A0A2I2YW34 ZNF766 PTHR24377:SF971 IP01015P-RELATED ZINC FINGER PROTEIN 766 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010460.3|UniProtKB=G3R4J6 G3R4J6 LYZL6 PTHR11407:SF9 LYSOZYME C LYSOZYME-LIKE PROTEIN 6 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;lysozyme activity#GO:0003796;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;single fertilization#GO:0007338;cellular process#GO:0009987;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;reproductive process#GO:0022414 cytoplasm#GO:0005737;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;secretory vesicle#GO:0099503;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;acrosomal vesicle#GO:0001669 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000016848.3|UniProtKB=G3RL11 G3RL11 ZRANB1 PTHR13367:SF28 UBIQUITIN THIOESTERASE UBIQUITIN THIOESTERASE ZRANB1 hydrolase activity#GO:0016787;protein binding#GO:0005515;deubiquitinase activity#GO:0101005;modification-dependent protein binding#GO:0140030;binding#GO:0005488;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;polyubiquitin modification-dependent protein binding#GO:0031593;catalytic activity#GO:0003824;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530 positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;post-translational protein modification#GO:0043687;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;positive regulation of canonical Wnt signaling pathway#GO:0090263;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of signal transduction#GO:0009967;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of Wnt signaling pathway#GO:0030177;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of signaling#GO:0023056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000011038.3|UniProtKB=G3R625 G3R625 STK11 PTHR24343:SF457 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE STK11 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000000979.3|UniProtKB=A0A2I2ZM66 A0A2I2ZM66 SSH1 PTHR45864:SF5 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 1 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;cytoskeletal protein binding#GO:0008092;hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488;actin binding#GO:0003779 regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 GORGO|Ensembl=ENSGGOG00000027584.2|UniProtKB=G3RUK1 G3RUK1 HIC1 PTHR24394:SF16 ZINC FINGER PROTEIN HYPERMETHYLATED IN CANCER 1 PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000023671.2|UniProtKB=G3S6M0 G3S6M0 PTGER1 PTHR11866:SF3 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP1 SUBTYPE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of biological quality#GO:0065008;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 PI3 kinase pathway#P00048>GPCR#P01204;Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 GORGO|Ensembl=ENSGGOG00000002346.3|UniProtKB=G3S6K4 G3S6K4 EHD2 PTHR11216:SF62 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;endocytic recycling#GO:0032456;cell projection organization#GO:0030030;localization within membrane#GO:0051668;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;transport#GO:0006810;intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection assembly#GO:0120031;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;recycling endosome#GO:0055037;organelle membrane#GO:0031090;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006934.3|UniProtKB=G3RQA9 G3RQA9 ACSS2 PTHR24095:SF126 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 organophosphate biosynthetic process#GO:0090407;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 GORGO|Ensembl=ENSGGOG00000026998.2|UniProtKB=G3RPS3 G3RPS3 ITM2A PTHR10962:SF7 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2A binding#GO:0005488;peptide binding#GO:0042277 negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000024078.2|UniProtKB=G3RYW9 G3RYW9 LGI4 PTHR24367:SF268 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 4 anatomical structure maturation#GO:0071695;peripheral nervous system development#GO:0007422;cell development#GO:0048468;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;developmental maturation#GO:0021700;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;myelination#GO:0042552;gliogenesis#GO:0042063;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell maturation#GO:0048469 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000003757.3|UniProtKB=G3QMF2 G3QMF2 SPA17 PTHR10699:SF16 NEUROMODULIN SPERM SURFACE PROTEIN SP17 calmodulin binding#GO:0005516;binding#GO:0005488;protein binding#GO:0005515 sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;sperm principal piece#GO:0097228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000016063.3|UniProtKB=G3SF90 G3SF90 GTSF1 PTHR21402:SF9 GAMETOCYTE SPECIFIC FACTOR 1-RELATED GAMETOCYTE-SPECIFIC FACTOR 1 GORGO|Ensembl=ENSGGOG00000001308.3|UniProtKB=G3QG43 G3QG43 MTF2 PTHR12628:SF12 POLYCOMB-LIKE TRANSCRIPTION FACTOR METAL-RESPONSE ELEMENT-BINDING TRANSCRIPTION FACTOR 2 chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000016012.3|UniProtKB=G3RIU9 G3RIU9 PTHR18945:SF82 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-6 molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic cation transmembrane transporter activity#GO:0008324;acetylcholine receptor activity#GO:0015464;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;neuromuscular synaptic transmission#GO:0007274;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536;response to nitrogen compound#GO:1901698;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of cell communication#GO:0010646;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;synaptic transmission, cholinergic#GO:0007271 membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cell junction#GO:0030054;transporter complex#GO:1990351 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA6#P06592;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 GORGO|Ensembl=ENSGGOG00000012012.3|UniProtKB=A0A2I2Y9R9 A0A2I2Y9R9 IFIT3 PTHR10271:SF3 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 3 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;cellular response to cytokine stimulus#GO:0071345;antiviral innate immune response#GO:0140374;defense response to virus#GO:0051607;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune system process#GO:0002376;response to peptide#GO:1901652;response to virus#GO:0009615 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014833.3|UniProtKB=G3RFU2 G3RFU2 OLFML1 PTHR23192:SF13 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 1 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000005800.3|UniProtKB=G3QSP0 G3QSP0 ESAM PTHR44549:SF1 ENDOTHELIAL CELL-SELECTIVE ADHESION MOLECULE ENDOTHELIAL CELL-SELECTIVE ADHESION MOLECULE binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000002487.3|UniProtKB=G3QJ69 G3QJ69 SIRT2 PTHR11085:SF6 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2 deacetylase activity#GO:0019213;histone modifying activity#GO:0140993;acyltransferase activity#GO:0016746;NAD-dependent protein lysine deacetylase activity#GO:0034979;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;nucleolus organization#GO:0007000;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of gene expression#GO:0010468;nucleus organization#GO:0006997;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000041137.1|UniProtKB=A0A2I2YXA1 A0A2I2YXA1 PTHR26453:SF81 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001279.3|UniProtKB=G3QG14 G3QG14 SYP PTHR10306:SF10 SYNAPTOPHYSIN SYNAPTOPHYSIN regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646 organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;cell junction#GO:0030054;presynaptic active zone#GO:0048786;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptophysin#P05777 GORGO|Ensembl=ENSGGOG00000012490.3|UniProtKB=G3R9U2 G3R9U2 LYN PTHR24418:SF42 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE LYN catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular component organization#GO:0016043;leukocyte differentiation#GO:0002521;immune response-regulating signaling pathway#GO:0002764;mononuclear cell differentiation#GO:1903131;regulation of biological process#GO:0050789;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;cellular response to stress#GO:0033554;immune system development#GO:0002520;neuron development#GO:0048666;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of B cell receptor signaling pathway#GO:0050855;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of immune response#GO:0050776;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of signal transduction#GO:0009966;hemopoiesis#GO:0030097;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;DNA damage response#GO:0006974;positive regulation of immune response#GO:0050778;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Lyn#P00374;CCKR signaling map#P06959>LYN#P07141;Parkinson disease#P00049>Src kinase#P01230;Cadherin signaling pathway#P00012>Yes#P00476 GORGO|Ensembl=ENSGGOG00000013928.3|UniProtKB=A0A2I2YA81 A0A2I2YA81 SF3A3 PTHR12786:SF3 SPLICING FACTOR SF3A-RELATED SPLICING FACTOR 3A SUBUNIT 3 snoRNA binding#GO:0030515;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;U2 snRNP#GO:0005686;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000007410.2|UniProtKB=G3QWT1 G3QWT1 TMEM203 PTHR13568:SF9 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 203 homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009906.3|UniProtKB=G3R352 G3R352 EMC6 PTHR20994:SF0 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;organelle assembly#GO:0070925;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;metabolic process#GO:0008152;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;macroautophagy#GO:0016236;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;cellular component assembly#GO:0022607;autophagy#GO:0006914;establishment of protein localization#GO:0045184;cellular process#GO:0009987;autophagosome organization#GO:1905037;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;EMC complex#GO:0072546;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 GORGO|Ensembl=ENSGGOG00000014378.3|UniProtKB=G3S726 G3S726 SRSF2 PTHR23147:SF145 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 2 membraneless organelle#GO:0043228;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000041087.1|UniProtKB=A0A2I2ZKY0 A0A2I2ZKY0 PTHR23268:SF6 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 5-5-RELATED cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000043454.1|UniProtKB=G3SH55 G3SH55 ZNF282 PTHR23232:SF121 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 282 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Gene=NDUFB7|UniProtKB=Q0MQE3 Q0MQE3 NDUFB7 PTHR20900:SF0 NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000025713.2|UniProtKB=G3S397 G3S397 SFR1 PTHR28643:SF1 SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 cellular response to stress#GO:0033554;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to stress#GO:0006950;positive regulation of macromolecule metabolic process#GO:0010604;recombinational repair#GO:0000725;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;DNA repair#GO:0006281;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000005519.3|UniProtKB=G3SE84 G3SE84 TERF2IP PTHR16466:SF6 TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance via telomere lengthening#GO:0010833;cellular process#GO:0009987;telomere capping#GO:0016233;organelle organization#GO:0006996;response to stress#GO:0006950;telomere organization#GO:0032200;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nuclear telomere cap complex#GO:0000783;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000001599.3|UniProtKB=G3QGW1 G3QGW1 SLC17A9 PTHR11662:SF279 SOLUTE CARRIER FAMILY 17 VOLTAGE-GATED PURINE NUCLEOTIDE UNIPORTER SLC17A9 nitrogen compound transport#GO:0071705;transport#GO:0006810;carbohydrate derivative transport#GO:1901264;establishment of localization#GO:0051234;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;localization#GO:0051179 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000022695.3|UniProtKB=G3SCQ0 G3SCQ0 KIF6 PTHR24115:SF194 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF6 polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000034979.2|UniProtKB=G3SKG3 G3SKG3 CCDC103 PTHR28572:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 103 DYNEIN AXONEMAL ASSEMBLY FACTOR 19 determination of left/right symmetry#GO:0007368;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;pattern specification process#GO:0007389;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;regionalization#GO:0003002;developmental process#GO:0032502;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;cilium organization#GO:0044782;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;determination of bilateral symmetry#GO:0009855;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;left/right pattern formation#GO:0060972;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 GORGO|Ensembl=ENSGGOG00000002426.3|UniProtKB=G3QJ11 G3QJ11 PTHR14463:SF5 LIPASE MATURATION FACTOR LIPASE MATURATION FACTOR 2 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000000019.3|UniProtKB=G3QCS3 G3QCS3 ZNF546 PTHR24377:SF142 IP01015P-RELATED ZINC FINGER PROTEIN 546 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005961.4|UniProtKB=G3QT29 G3QT29 REDIC1 PTHR35158:SF1 CDNA SEQUENCE CN725425 REGULATOR OF DNA CLASS I CROSSOVER INTERMEDIATES 1 GORGO|Ensembl=ENSGGOG00000011086.3|UniProtKB=G3R669 G3R669 PPIB PTHR11071:SF477 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000003794.3|UniProtKB=G3QMI8 G3QMI8 TMEM116 PTHR23112:SF51 G PROTEIN-COUPLED RECEPTOR 157-RELATED TRANSMEMBRANE PROTEIN 116 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000026599.2|UniProtKB=A0A2I2YY13 A0A2I2YY13 PIP5K1A PTHR23086:SF54 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 ALPHA kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transferase#PC00220;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000005103.3|UniProtKB=A0A2I2Y270 A0A2I2Y270 N4BP2 PTHR46535:SF1 NEDD4-BINDING PROTEIN 2 NEDD4-BINDING PROTEIN 2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;nuclease activity#GO:0004518 GORGO|Ensembl=ENSGGOG00000014692.3|UniProtKB=G3RFH0 G3RFH0 EEIG1 PTHR21456:SF2 FAMILY WITH SEQUENCE SIMILARITY 102 EARLY ESTROGEN-INDUCED GENE 1 PROTEIN GORGO|Ensembl=ENSGGOG00000000277.3|UniProtKB=G3QDF6 G3QDF6 ZNF541 PTHR16089:SF23 REST COREPRESSOR COREST PROTEIN-RELATED ZINC FINGER PROTEIN 541 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000022639.2|UniProtKB=A0A2I2YJ33 A0A2I2YJ33 LRIG2 PTHR24366:SF64 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEATS AND IMMUNOGLOBULIN LIKE DOMAINS 2 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000011553.3|UniProtKB=G3R7D2 G3R7D2 FICD PTHR13504:SF34 FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145 PROTEIN ADENYLYLTRANSFERASE FICD phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 GORGO|Ensembl=ENSGGOG00000000857.3|UniProtKB=G3QEY7 G3QEY7 S100A9 PTHR11639:SF79 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A9 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515 neutrophil chemotaxis#GO:0030593;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;gliogenesis#GO:0042063;multicellular organism development#GO:0007275;leukocyte cell-cell adhesion#GO:0007159;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;taxis#GO:0042330;response to chemical#GO:0042221;neutrophil migration#GO:1990266;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;cell adhesion#GO:0007155;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;granulocyte chemotaxis#GO:0071621;central nervous system development#GO:0007417;response to stimulus#GO:0050896;developmental process#GO:0032502;leukocyte migration#GO:0050900;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;immune response#GO:0006955;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;response to other organism#GO:0051707;cell migration#GO:0016477;endothelial cell migration#GO:0043542;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cell chemotaxis#GO:0060326;system development#GO:0048731;cell communication#GO:0007154;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cell motility#GO:0048870 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000025278.2|UniProtKB=G3S0U3 G3S0U3 AMH PTHR15009:SF4 MUELLERIAN-INHIBITING FACTOR ANTI-MUELLERIAN HORMONE protein binding#GO:0005515;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488 animal gross anatomical part developmental process#GO:0160108;reproductive system development#GO:0061458;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;developmental process involved in reproduction#GO:0003006;reproductive structure development#GO:0048608;reproductive process#GO:0022414;male sex differentiation#GO:0046661;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;development of primary male sexual characteristics#GO:0046546;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;gonad development#GO:0008406;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Gonadotropin-releasing hormone receptor pathway#P06664>MIS#P06750 GORGO|Ensembl=ENSGGOG00000025061.2|UniProtKB=G3S5Z9 G3S5Z9 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000006359.3|UniProtKB=G3QU31 G3QU31 GLRA3 PTHR18945:SF455 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-3 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic anion transmembrane transporter activity#GO:0008509 chloride transport#GO:0006821;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220 postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000038483.1|UniProtKB=A0A2I2YP41 A0A2I2YP41 LOC101125649 PTHR26452:SF812 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AC2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000186.3|UniProtKB=A0A2I2YE90 A0A2I2YE90 DAB2IP PTHR10194:SF26 RAS GTPASE-ACTIVATING PROTEINS DISABLED HOMOLOG 2-INTERACTING PROTEIN GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 GORGO|Ensembl=ENSGGOG00000028164.2|UniProtKB=G3S3P0 G3S3P0 NT5C3A PTHR13045:SF14 5'-NUCLEOTIDASE CYTOSOLIC 5'-NUCLEOTIDASE 3A hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 esterase#PC00097;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000024499.2|UniProtKB=G3S4I5 G3S4I5 LOC101154368 PTHR11071:SF466 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A-LIKE 4C-RELATED intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000023535.2|UniProtKB=G3S7U5 G3S7U5 ARMC8 PTHR15651:SF7 ARMADILLO REPEAT-CONTAINING PROTEIN 8 ARMADILLO REPEAT-CONTAINING PROTEIN 8 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000043840.1|UniProtKB=A0A2I2YCH2 A0A2I2YCH2 PTHR24075:SF12 SEC63 DOMAIN-CONTAINING SEC63 DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853 cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002321.3|UniProtKB=A0A2I2Y765 A0A2I2Y765 MYO1B PTHR13140:SF277 MYOSIN UNCONVENTIONAL MYOSIN-IB isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146 cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;cellular process#GO:0009987;actin filament-based movement#GO:0030048;organelle organization#GO:0006996;actin filament organization#GO:0007015;system process#GO:0003008;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;sensory perception of sound#GO:0007605;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;localization#GO:0051179;actin filament-based process#GO:0030029;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;brush border#GO:0005903;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000002267.3|UniProtKB=G3QIL9 G3QIL9 BATF PTHR23351:SF14 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000022517.2|UniProtKB=G3SAB4 G3SAB4 EID2 PTHR15556:SF3 EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2-RELATED EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003563.3|UniProtKB=G3QLX5 G3QLX5 DPT PTHR15040:SF2 DERMATOPONTIN-RELATED DERMATOPONTIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization#GO:0016043 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000042024.1|UniProtKB=A0A2I2ZWY0 A0A2I2ZWY0 C1H1orf21 PTHR14974:SF3 SIMILAR TO RIKEN CDNA 1700025G04 GENE SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 21 GORGO|Ensembl=ENSGGOG00000017044.3|UniProtKB=A0A2I2Z0Z0 A0A2I2Z0Z0 KCTD17 PTHR14958:SF24 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD17 protein binding#GO:0005515;binding#GO:0005488 positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;regulation of cell projection organization#GO:0031344;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of cilium assembly#GO:1902017;macromolecule metabolic process#GO:0043170;regulation of plasma membrane bounded cell projection organization#GO:0120035;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;protein catabolic process#GO:0030163;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of organelle organization#GO:0010638;protein metabolic process#GO:0019538;regulation of cell projection assembly#GO:0060491 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012013.3|UniProtKB=A0A2I2YFD3 A0A2I2YFD3 IRF5 PTHR11949:SF10 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell surface receptor signaling pathway#GO:0007166 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000041019.1|UniProtKB=A0A2I2ZVX8 A0A2I2ZVX8 PTHR23266:SF238 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 4-34 antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000040352.1|UniProtKB=A0A2I2YJ83 A0A2I2YJ83 L1CAM PTHR10075:SF77 BASIGIN RELATED NEURONAL-GLIAL CELL ADHESION MOLECULE cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000009334.3|UniProtKB=A0A2I2ZE46 A0A2I2ZE46 MTX1 PTHR12289:SF34 METAXIN RELATED METAXIN-1 establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial outer membrane translocase complex#GO:0005742;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012441.3|UniProtKB=G3R9Q2 G3R9Q2 RRP9 PTHR19865:SF0 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000000589.3|UniProtKB=G3QE88 G3QE88 PRAF2 PTHR11227:SF44 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 4 anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981 primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;vacuole organization#GO:0007033;localization#GO:0051179;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;intracellular protein localization#GO:0008104;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;phagophore assembly site#GO:0000407;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022554.2|UniProtKB=G3RMK5 G3RMK5 PFDN1 PTHR20903:SF1 PREFOLDIN SUBUNIT 1-RELATED PREFOLDIN SUBUNIT 1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000005231.3|UniProtKB=G3RRY5 G3RRY5 THUMPD1 PTHR13452:SF15 THUMP DOMAIN CONTAINING PROTEIN 1-RELATED THUMP DOMAIN-CONTAINING PROTEIN 1 protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000004774.3|UniProtKB=A0A2I2Z818 A0A2I2Z818 KIF2A PTHR24115:SF486 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2A hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092 cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;microtubule-based movement#GO:0007018;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000038271.1|UniProtKB=A0A2I2Z907 A0A2I2Z907 CCDC107 PTHR37345:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 107 COILED-COIL DOMAIN-CONTAINING PROTEIN 107 GORGO|Ensembl=ENSGGOG00000013305.3|UniProtKB=A0A2I2Y1Q6 A0A2I2Y1Q6 NLGN3 PTHR43903:SF4 NEUROLIGIN NEUROLIGIN-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 synaptic vesicle cycle#GO:0099504;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;biological regulation#GO:0065007;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;synaptic vesicle endocytosis#GO:0048488;regulation of cell communication#GO:0010646;postsynapse organization#GO:0099173;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;cellular localization#GO:0051641;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;signaling#GO:0023052;endocytosis#GO:0006897;synapse assembly#GO:0007416 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000007656.3|UniProtKB=A0A2I2Z783 A0A2I2Z783 SLC4A5 PTHR11453:SF20 ANION EXCHANGE PROTEIN ELECTROGENIC SODIUM BICARBONATE COTRANSPORTER 4 active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;bicarbonate transmembrane transporter activity#GO:0015106;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;system process#GO:0003008;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;renal system process#GO:0003014;cellular process#GO:0009987 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000040174.1|UniProtKB=A0A2I2YDN0 A0A2I2YDN0 PTHR45837:SF3 VESICLE-TRAFFICKING PROTEIN SEC22B VESICLE-TRAFFICKING PROTEIN SEC22B SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;vesicle fusion#GO:0006906;Golgi organization#GO:0007030;cellular component organization#GO:0016043 cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;ER to Golgi transport vesicle membrane#GO:0012507;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827 GORGO|Ensembl=ENSGGOG00000006493.3|UniProtKB=G3QUF0 G3QUF0 ERG28 PTHR15451:SF19 ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014879.3|UniProtKB=G3RFY8 G3RFY8 TTC23 PTHR14485:SF3 TETRATRICOPEPTIDE REPEAT PROTEIN 23 TETRATRICOPEPTIDE REPEAT PROTEIN 23 GORGO|Ensembl=ENSGGOG00000015371.3|UniProtKB=G3RH77 G3RH77 FAM200C PTHR45935:SF18 PROTEIN ZBED8-RELATED PROTEIN FAM200C GORGO|Ensembl=ENSGGOG00000014249.3|UniProtKB=G3REC3 G3REC3 BRPF1 PTHR13793:SF85 PHD FINGER PROTEINS PEREGRIN chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000016263.3|UniProtKB=G3SAN6 G3SAN6 ANKRD30A PTHR24147:SF63 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 30A GORGO|Ensembl=ENSGGOG00000016676.3|UniProtKB=G3RKK0 G3RKK0 ART4 PTHR10339:SF1 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 4 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009604.3|UniProtKB=G3R2D3 G3R2D3 LSAMP PTHR42757:SF22 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED LIMBIC SYSTEM-ASSOCIATED MEMBRANE PROTEIN regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;cell adhesion#GO:0007155;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of synapse assembly#GO:0051963;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000039386.1|UniProtKB=A0A2I2YA72 A0A2I2YA72 CHST5 PTHR10704:SF13 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 5 transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004399.3|UniProtKB=G3QP29 G3QP29 DLX5 PTHR24327:SF31 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development ending in birth or egg hatching#GO:0009792;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000001070.3|UniProtKB=G3QD74 G3QD74 RASAL2 PTHR10194:SF52 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN NGAP GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 GORGO|Ensembl=ENSGGOG00000039350.1|UniProtKB=A0A2I2YVG7 A0A2I2YVG7 LOC101132095 PTHR15336:SF3 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 reductase#PC00198;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000027952.2|UniProtKB=G3RT07 G3RT07 LOC101127384 PTHR24300:SF409 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2A13 binding#GO:0005488;tetrapyrrole binding#GO:0046906;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 arachidonate metabolic process#GO:0019369;cellular response to stimulus#GO:0051716;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;xenobiotic metabolic process#GO:0006805;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;response to xenobiotic stimulus#GO:0009410;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;olefinic compound metabolic process#GO:0120254;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;secondary metabolic process#GO:0019748 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 Nicotine degradation#P05914>CYP2A6#P05984 GORGO|Ensembl=ENSGGOG00000001969.3|UniProtKB=G3QHV1 G3QHV1 ADRA1B PTHR24248:SF17 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1B ADRENERGIC RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;regulation of biological quality#GO:0065008;adrenergic receptor signaling pathway#GO:0071875 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000003685.4|UniProtKB=G3QM91 G3QM91 KLHL18 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000038263.1|UniProtKB=A0A2I2Y8W7 A0A2I2Y8W7 PTHR48034:SF20 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA BINDING MOTIF PROTEIN, X-LINKED-LIKE-1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000011136.3|UniProtKB=G3R6B4 G3R6B4 CPNE4 PTHR10857:SF4 COPINE COPINE-4 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 response to chemical#GO:0042221;response to stimulus#GO:0050896;response to calcium ion#GO:0051592;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to metal ion#GO:0010038;cellular response to chemical stimulus#GO:0070887 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000004191.3|UniProtKB=G3QNJ8 G3QNJ8 TKTL1 PTHR43195:SF2 TRANSKETOLASE TRANSKETOLASE-LIKE PROTEIN 1 anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;transketolase activity#GO:0004802;transketolase or transaldolase activity#GO:0016744;catalytic activity#GO:0003824;transferase activity#GO:0016740;heterocyclic compound binding#GO:1901363 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transketolase#PC00221;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000042572.1|UniProtKB=A0A2I2Y266 A0A2I2Y266 PTHR11570:SF0 S-ADENOSYLMETHIONINE DECARBOXYLASE S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME decarboxylase#PC00089;lyase#PC00144;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000001478.3|UniProtKB=G3QGK4 G3QGK4 ANKMY1 PTHR15897:SF2 ANKYRIN REPEAT AND MYND DOMAIN PROTEIN 1 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000011925.3|UniProtKB=G3R8C4 G3R8C4 ANAPC13 PTHR28672:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein K11-linked ubiquitination#GO:0070979;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000009895.3|UniProtKB=G3R347 G3R347 ADORA1 PTHR24246:SF1 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 GORGO|Ensembl=ENSGGOG00000024003.2|UniProtKB=A0A2I2ZI58 A0A2I2ZI58 ZNF207 PTHR23215:SF6 ZINC FINGER PROTEIN 207 BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;nuclear division#GO:0000280;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;negative regulation of cell cycle phase transition#GO:1901988;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic sister chromatid segregation#GO:0033047;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;negative regulation of organelle organization#GO:0010639;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;metaphase chromosome alignment#GO:0051310;microtubule-based process#GO:0007017;negative regulation of cell cycle#GO:0045786;mitotic spindle assembly checkpoint signaling#GO:0007094;attachment of spindle microtubules to kinetochore#GO:0008608;spindle assembly#GO:0051225;chromosome localization#GO:0050000;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;spindle organization#GO:0007051;regulation of mitotic cell cycle#GO:0007346;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;organelle localization#GO:0051640;organelle assembly#GO:0070925;negative regulation of chromosome organization#GO:2001251;intracellular signal transduction#GO:0035556;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell communication#GO:0007154;localization#GO:0051179;negative regulation of cellular component organization#GO:0051129;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000004017.3|UniProtKB=G3QN36 G3QN36 SLC5A8 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 monocarboxylic acid transport#GO:0015718;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;fatty acid transport#GO:0015908;transmembrane transport#GO:0055085;lipid localization#GO:0010876;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010587.3|UniProtKB=G3R4V9 G3R4V9 TRIM42 PTHR25465:SF13 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 42 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000041086.1|UniProtKB=G3SG94 G3SG94 HTR3E PTHR18945:SF764 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3E monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;response to nitrogen compound#GO:1901698;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000004335.3|UniProtKB=G3QNX6 G3QNX6 PATL1 PTHR21551:SF2 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PROTEIN PAT1 HOMOLOG 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;membraneless organelle assembly#GO:0140694;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;cellular component assembly#GO:0022607;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;organelle assembly#GO:0070925;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;negative regulation of protein metabolic process#GO:0051248;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;P-body assembly#GO:0033962;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;RNA decapping#GO:0110154;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;nucleus#GO:0005634 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012158.3|UniProtKB=Q2IBE7 Q2IBE7 CAPZA2 PTHR10653:SF2 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of protein depolymerization#GO:1901879;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;regulation of actin filament depolymerization#GO:0030834;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000008691.3|UniProtKB=G3R023 G3R023 ZHX3 PTHR15467:SF6 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000014681.3|UniProtKB=A0A2I2YK32 A0A2I2YK32 ZNF334 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000042541.1|UniProtKB=A0A2I2ZKE2 A0A2I2ZKE2 C5H6orf132 PTHR35077:SF2 SIMILAR TO AI661453 PROTEIN SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 132 GORGO|Ensembl=ENSGGOG00000010096.3|UniProtKB=G3RM31 G3RM31 STOX1 PTHR22437:SF1 WINGED HELIX DOMAIN-CONTAINING PROTEIN STORKHEAD-BOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002975.3|UniProtKB=G3QKF0 G3QKF0 MEN1 PTHR12693:SF3 MENIN MENIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;response to stress#GO:0006950;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;DNA-templated transcription initiation#GO:0006352;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 CCKR signaling map#P06959>MEN1#P07084 GORGO|Ensembl=ENSGGOG00000007375.3|UniProtKB=G3QWQ1 G3QWQ1 H1-4 PTHR11467:SF179 HISTONE H1 HISTONE H1.4 chromatin DNA binding#GO:0031490;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;DNA binding#GO:0003677;nucleosome binding#GO:0031491;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;regulation of DNA recombination#GO:0000018 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000025867.2|UniProtKB=G3RX12 G3RX12 ICE1 PTHR11852:SF4 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE LITTLE ELONGATION COMPLEX SUBUNIT 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;snRNA transcription by RNA polymerase III#GO:0042796;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;snRNA transcription#GO:0009301;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016158.3|UniProtKB=G3RYT0 G3RYT0 CRX PTHR45793:SF22 HOMEOBOX PROTEIN CONE-ROD HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000011145.3|UniProtKB=G3R6C0 G3R6C0 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 ceramide metabolic process#GO:0006672;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000014125.3|UniProtKB=G3RE18 G3RE18 CMSS1 PTHR24030:SF0 PROTEIN CMSS1 PROTEIN CMSS1 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000028471.2|UniProtKB=G3RVC8 G3RVC8 LOC101124795 PTHR11818:SF142 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN E-RELATED structural molecule activity#GO:0005198 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000024832.2|UniProtKB=G3S6G9 G3S6G9 CYLC2 PTHR16742:SF2 CYCLICIN CYLICIN-2 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000005745.3|UniProtKB=A0A2I2ZEV5 A0A2I2ZEV5 P3H1 PTHR14049:SF5 LEPRECAN 1 PROLYL 3-HYDROXYLASE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular process#GO:0009987;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000011091.3|UniProtKB=G3R672 G3R672 CNOT9 PTHR12262:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;P-body#GO:0000932;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;CCR4-NOT complex#GO:0030014 GORGO|Ensembl=ENSGGOG00000022340.2|UniProtKB=A0A2I2ZC69 A0A2I2ZC69 PTHR13968:SF36 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RRM DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008818.4|UniProtKB=G3R0D8 G3R0D8 SLC9A7 PTHR10110:SF62 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 7 metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;recycling endosome#GO:0055037 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000039307.1|UniProtKB=A0A2I2YEM2 A0A2I2YEM2 MZT1 PTHR28520:SF15 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 microtubule polymerization or depolymerization#GO:0031109;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule polymerization#GO:0046785;chromosome organization#GO:0051276;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;chromosome segregation#GO:0007059;mitotic spindle organization#GO:0007052;microtubule nucleation#GO:0007020;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;nuclear division#GO:0000280 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000027555.2|UniProtKB=G3S0W8 G3S0W8 NEK9 PTHR44535:SF1 PROTEIN CBG16200 SERINE_THREONINE-PROTEIN KINASE NEK9 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle#GO:0007049 GORGO|Ensembl=ENSGGOG00000008502.3|UniProtKB=G3QZK3 G3QZK3 DENND2C PTHR15288:SF6 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2C molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000009352.3|UniProtKB=G3R1Q4 G3R1Q4 A4GALT PTHR12042:SF17 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000016842.3|UniProtKB=A0A2I2YKR5 A0A2I2YKR5 SGCB PTHR21142:SF2 SARCOGLYCANS BETA-SARCOGLYCAN sarcolemma#GO:0042383;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000006995.3|UniProtKB=G3QVR8 G3QVR8 TMC6 PTHR23302:SF4 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 6 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000011197.3|UniProtKB=G3SH60 G3SH60 C1QTNF1 PTHR22923:SF63 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 1 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 negative regulation of response to wounding#GO:1903035;negative regulation of response to external stimulus#GO:0032102;regulation of multicellular organismal process#GO:0051239;negative regulation of cell-cell adhesion#GO:0022408;regulation of response to external stimulus#GO:0032101;regulation of response to wounding#GO:1903034;regulation of biological quality#GO:0065008;negative regulation of coagulation#GO:0050819;negative regulation of hemostasis#GO:1900047;regulation of platelet aggregation#GO:0090330;regulation of wound healing#GO:0061041;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of biological process#GO:0048519;negative regulation of cell activation#GO:0050866;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;negative regulation of blood coagulation#GO:0030195;biological regulation#GO:0065007;regulation of coagulation#GO:0050818;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;negative regulation of response to stimulus#GO:0048585;regulation of hemostasis#GO:1900046;negative regulation of wound healing#GO:0061045;regulation of platelet activation#GO:0010543;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;negative regulation of multicellular organismal process#GO:0051241 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001848.3|UniProtKB=A0A2I2YMX0 A0A2I2YMX0 ESPN PTHR24153:SF14 ESPIN ESPIN actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 plasma membrane bounded cell projection assembly#GO:0120031;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cell projection organization#GO:0030030 actin-based cell projection#GO:0098858;neuron projection#GO:0043005;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stereocilium#GO:0032420;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000014467.3|UniProtKB=G3REW0 G3REW0 SURF2 PTHR34348:SF1 SURFEIT LOCUS PROTEIN 2 SURFEIT LOCUS PROTEIN 2 GORGO|Ensembl=ENSGGOG00000001949.3|UniProtKB=G3S6Q5 G3S6Q5 FBXO3 PTHR46550:SF7 F-BOX ONLY PROTEIN 3 F-BOX ONLY PROTEIN 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000025508.2|UniProtKB=G3SE94 G3SE94 PTHR23239:SF349 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 18 intermediate filament cytoskeleton organization#GO:0045104;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;intermediate filament-based process#GO:0045103;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000024429.2|UniProtKB=A0A2I2YSS0 A0A2I2YSS0 PTHR10653:SF19 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of protein depolymerization#GO:1901879;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament organization#GO:0110053;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000023939.2|UniProtKB=G3S587 G3S587 FBXO24 PTHR47004:SF1 F-BOX ONLY PROTEIN 24 F-BOX ONLY PROTEIN 24 GORGO|Ensembl=ENSGGOG00000023282.2|UniProtKB=G3RPS1 G3RPS1 PTHR19918:SF45 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;binding#GO:0005488 biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;primary metabolic process#GO:0044238;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;proteasomal protein catabolic process#GO:0010498;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;metabolic process#GO:0008152;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of metabolic process#GO:0009893;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023395.2|UniProtKB=G3SCC6 G3SCC6 SNX19 PTHR22775:SF31 SORTING NEXIN SORTING NEXIN-19 ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000041740.1|UniProtKB=A0A2I2ZLV6 A0A2I2ZLV6 PTHR20855:SF40 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>AdipoR1/R2#P06706 GORGO|Ensembl=ENSGGOG00000014708.3|UniProtKB=G3RFK3 G3RFK3 FREM1 PTHR45739:SF7 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1 cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010121.3|UniProtKB=G3R3P3 G3R3P3 RPS19BP1 PTHR31454:SF2 ACTIVE REGULATOR OF SIRT1 ACTIVE REGULATOR OF SIRT1 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000025985.2|UniProtKB=G3RN16 G3RN16 PTHR24393:SF190 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 13 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015715.3|UniProtKB=Q8HY06 Q8HY06 CLEC4M PTHR22802:SF438 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER M signaling receptor activity#GO:0038023;monosaccharide binding#GO:0048029;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;small molecule binding#GO:0036094;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000043992.1|UniProtKB=G3RUF6 G3RUF6 ORM1 PTHR11967:SF2 ALPHA-1-ACID GLYCOPROTEIN ALPHA-1-ACID GLYCOPROTEIN 1 defense response#GO:0006952;acute inflammatory response#GO:0002526;response to stimulus#GO:0050896;inflammatory response#GO:0006954;immune response#GO:0006955;response to stress#GO:0006950;immune system process#GO:0002376 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000026757.1|UniProtKB=G3RZR3 G3RZR3 ND3 PTHR11058:SF26 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NADH dehydrogenase activity#GO:0003954 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Gene=TAS2R38|UniProtKB=Q697L4 Q697L4 TAS2R38 PTHR11394:SF52 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 38 transmembrane signaling receptor activity#GO:0004888;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089 detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013348.3|UniProtKB=G3RC02 G3RC02 FAM234A PTHR21419:SF7 FAMILY NOT NAMED PROTEIN FAM234A cell surface#GO:0009986;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000006232.3|UniProtKB=A0A2I2ZYE1 A0A2I2ZYE1 NCR1 PTHR11738:SF4 MHC CLASS I NK CELL RECEPTOR IMMUNOGLOBULIN ALPHA FC RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 cell communication#GO:0007154;regulation of immune response#GO:0050776;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000002203.3|UniProtKB=G3QIG6 G3QIG6 MROH2B PTHR23120:SF22 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 2B secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141 GORGO|Ensembl=ENSGGOG00000003121.3|UniProtKB=G3QKT4 G3QKT4 ENC1 PTHR24410:SF5 HL07962P-RELATED ECTODERM-NEURAL CORTEX PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000003585.3|UniProtKB=A0A2I2YAD6 A0A2I2YAD6 CDK14 PTHR24056:SF154 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 14 cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;cyclin binding#GO:0030332;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 mitotic cell cycle#GO:0000278;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;cell cycle G2/M phase transition#GO:0044839;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;protein kinase complex#GO:1902911;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016289.3|UniProtKB=G3SFM3 G3SFM3 COPS5 PTHR10410:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 5 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237 regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229 translation initiation factor#PC00224;translation factor#PC00223 PDGF signaling pathway#P00047>c-Jun#P01163 GORGO|Ensembl=ENSGGOG00000023658.2|UniProtKB=G3S3E0 G3S3E0 LMBRD2 PTHR21355:SF19 G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 G PROTEIN-COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011491.3|UniProtKB=G3SDU5 G3SDU5 PTHR18950:SF1 PROGESTERONE-INDUCED BLOCKING FACTOR 1 PROGESTERONE-INDUCED-BLOCKING FACTOR 1 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000028282.2|UniProtKB=G3SG91 G3SG91 LOC101147167 PTHR48018:SF106 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M11 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010168.3|UniProtKB=G3R3T7 G3R3T7 PTHR15880:SF1 ASPARTATE-RICH PROTEIN 1 CHROMOSOME 22 OPEN READING FRAME 42 GORGO|Ensembl=ENSGGOG00000006889.3|UniProtKB=G3QVG9 G3QVG9 CDC37L1 PTHR12800:SF2 CDC37-RELATED HSP90 CO-CHAPERONE CDC37-LIKE 1 heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of protein stability#GO:0031647;primary metabolic process#GO:0044238;protein folding#GO:0006457;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein folding chaperone complex#GO:0101031;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000006880.3|UniProtKB=G3QVG2 G3QVG2 PPP1R27 PTHR46899:SF4 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27 protein binding#GO:0005515;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000015152.3|UniProtKB=G3RGN4 G3RGN4 MRPS11 PTHR11759:SF76 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001595.3|UniProtKB=G3QGV6 G3QGV6 IMP4 PTHR22734:SF2 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;rRNA binding#GO:0019843 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000026876.2|UniProtKB=A4H238 A4H238 DEFB125 PTHR15001:SF12 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 125 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;cell killing#GO:0001906;immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000011877.4|UniProtKB=G3R894 G3R894 PTHR10177:SF496 CYCLINS CYCLIN-F enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000011533.3|UniProtKB=A0A2I2ZDN3 A0A2I2ZDN3 PTHR12022:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 7 cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773 cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex III#GO:0045275;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000017082.3|UniProtKB=G3RLL6 G3RLL6 GMPS PTHR11922:SF6 GMP SYNTHASE-RELATED GMP SYNTHASE [GLUTAMINE-HYDROLYZING] ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 De novo purine biosynthesis#P02738>GMP synthase#P02899 GORGO|Ensembl=ENSGGOG00000022114.2|UniProtKB=G3RUT1 G3RUT1 DYNLL1 PTHR11886:SF118 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 1, CYTOPLASMIC binding#GO:0005488;protein binding#GO:0005515 cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;cilium assembly#GO:0060271;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111 cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000011561.3|UniProtKB=G3R7E7 G3R7E7 FBLN2 PTHR24034:SF158 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN 2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000007072.3|UniProtKB=G3QVY0 G3QVY0 IFRD2 PTHR12354:SF8 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 2 GORGO|Ensembl=ENSGGOG00000023863.2|UniProtKB=G3SB88 G3SB88 FLRT3 PTHR45712:SF12 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT3 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015653.3|UniProtKB=G3RHZ2 G3RHZ2 GLT8D2 PTHR13778:SF2 GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN 2 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001403.3|UniProtKB=G3QGD1 G3QGD1 MS4A3 PTHR23320:SF74 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 3 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000043978.1|UniProtKB=A0A2I2YPK5 A0A2I2YPK5 ZCCHC10 PTHR13491:SF0 ZCCHC10 PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10 GORGO|Ensembl=ENSGGOG00000013365.3|UniProtKB=G3RC23 G3RC23 MAN2B1 PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 glycosidase#PC00110;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000012261.3|UniProtKB=G3R989 G3R989 MEIOB PTHR21166:SF2 CELL DIVISION CONTROL PROTEIN 24 OB DOMAIN-CONTAINING PROTEIN-RELATED MEIOSIS-SPECIFIC WITH OB DOMAIN-CONTAINING PROTEIN DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;hydrolase activity#GO:0016787 sexual reproduction#GO:0019953;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;reproductive process#GO:0022414;homologous recombination#GO:0035825;DNA damage response#GO:0006974;DNA repair#GO:0006281;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;response to stimulus#GO:0050896;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000001752.3|UniProtKB=G3QHA2 G3QHA2 SARS1 PTHR11778:SF7 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000008514.4|UniProtKB=G3QZL2 G3QZL2 FSTL5 PTHR10913:SF44 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 5 developmental process#GO:0032502;cellular process#GO:0009987;cell differentiation#GO:0030154;cellular developmental process#GO:0048869 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000006822.2|UniProtKB=A0A2I2Y2V3 A0A2I2Y2V3 FGF14 PTHR11486:SF18 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 14 signaling receptor regulator activity#GO:0030545;ion channel regulator activity#GO:0099106;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104;transporter regulator activity#GO:0141108;binding#GO:0005488;signaling receptor binding#GO:0005102;channel regulator activity#GO:0016247;molecular function activator activity#GO:0140677;protein binding#GO:0005515 cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;response to fibroblast growth factor#GO:0071774;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000014287.3|UniProtKB=G3RR12 G3RR12 ABCA3 PTHR19229:SF98 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA3 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000005912.3|UniProtKB=G3QSY5 G3QSY5 RNF135 PTHR25465:SF41 B-BOX DOMAIN CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF135 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;regulation of response to external stimulus#GO:0032101;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of innate immune response#GO:0045088 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000013682.3|UniProtKB=G3RCW0 G3RCW0 PTHR13473:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L48 LARGE RIBOSOMAL SUBUNIT PROTEIN ML48 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012582.3|UniProtKB=A0A2I2ZE17 A0A2I2ZE17 RYR2 PTHR46399:SF7 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 2 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836 multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;system process#GO:0003008;calcium ion transport#GO:0006816;muscle contraction#GO:0006936;transport#GO:0006810;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;muscle system process#GO:0003012;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;I band#GO:0031674;membraneless organelle#GO:0043228;sarcolemma#GO:0042383;organelle membrane#GO:0031090;membrane#GO:0016020;Z disc#GO:0030018;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;organelle subcompartment#GO:0031984;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;cation channel complex#GO:0034703;transporter complex#GO:1990351;sarcomere#GO:0030017;bounding membrane of organelle#GO:0098588;contractile muscle fiber#GO:0043292;sarcoplasmic reticulum#GO:0016529;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;sarcoplasmic reticulum membrane#GO:0033017;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 CCKR signaling map#P06959>RYR1/2/3#P07088;Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441 GORGO|Ensembl=ENSGGOG00000000905.3|UniProtKB=G3QF29 G3QF29 MARCHF3 PTHR46065:SF2 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF3 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000014189.3|UniProtKB=G3RE75 G3RE75 CFAP61 PTHR21178:SF8 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000024916.2|UniProtKB=A0A2I2YHI9 A0A2I2YHI9 PTHR10139:SF3 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 DOUBLE-STRAND BREAK REPAIR PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520 negative regulation of mitotic cell cycle phase transition#GO:1901991;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;meiotic DNA double-strand break formation#GO:0042138;negative regulation of cell cycle G2/M phase transition#GO:1902750;cellular component organization or biogenesis#GO:0071840;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;biological regulation#GO:0065007;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;primary metabolic process#GO:0044238;telomere organization#GO:0032200;regulation of G2/M transition of mitotic cell cycle#GO:0010389;sexual reproduction#GO:0019953;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;response to stress#GO:0006950;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786;DNA recombination#GO:0006310;metabolic process#GO:0008152;signaling#GO:0023052;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;telomere maintenance#GO:0000723;double-strand break repair via nonhomologous end joining#GO:0006303;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009385.3|UniProtKB=G3R1U1 G3R1U1 SFXN2 PTHR11153:SF14 SIDEROFLEXIN SIDEROFLEXIN-2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;localization#GO:0051179;cellular localization#GO:0051641;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000043345.1|UniProtKB=G3RXW3 G3RXW3 LOC101149752 PTHR28163:SF1 PROTEIN PET117 HOMOLOG, MITOCHONDRIAL PROTEIN PET117 HOMOLOG, MITOCHONDRIAL cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000026356.2|UniProtKB=G3RU12 G3RU12 TNFRSF25 PTHR47220:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 25 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 25 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003824.3|UniProtKB=G3QML4 G3QML4 AUH PTHR11941:SF12 ENOYL-COA HYDRATASE-RELATED METHYLGLUTACONYL-COA HYDRATASE, MITOCHONDRIAL hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000467.3|UniProtKB=G3S9S1 G3S9S1 CD248 PTHR14789:SF4 CHONDROLECTIN VARIANT CHODLFDELTAE. ENDOSIALIN binding#GO:0005488;extracellular matrix binding#GO:0050840;protein binding#GO:0005515 cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000722.3|UniProtKB=G3S1W2 G3S1W2 ITGA5 PTHR23220:SF3 INTEGRIN ALPHA INTEGRIN ALPHA-5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;blood vessel morphogenesis#GO:0048514;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;tube development#GO:0035295;multicellular organismal process#GO:0032501 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000000281.3|UniProtKB=A0A2I2ZRJ2 A0A2I2ZRJ2 PLAAT4 PTHR13943:SF36 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 4 phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycerophospholipase activity#GO:0004620;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;A2-type glycerophospholipase activity#GO:0004623;carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;hydrolase activity#GO:0016787 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000012902.3|UniProtKB=A0A2I2YZ33 A0A2I2YZ33 LOC101130821 PTHR26452:SF701 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 11L1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000002842.3|UniProtKB=G3QK30 G3QK30 CXCL14 PTHR12015:SF202 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 14 defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune system process#GO:0002376;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to external stimulus#GO:0009605;defense response#GO:0006952;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000013930.3|UniProtKB=G3RDI4 G3RDI4 CD276 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000003835.3|UniProtKB=A0A2I2Y401 A0A2I2Y401 INTS3 PTHR13587:SF7 INTEGRATOR COMPLEX SUBUNIT 3 INTEGRATOR COMPLEX SUBUNIT 3 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011753.3|UniProtKB=G3R7W1 G3R7W1 MARCKSL1 PTHR14353:SF8 MYRISTOYLATED ALANINE-RICH C-KINASE SUBSTRATE MARCKS MARCKS-RELATED PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;developmental process#GO:0032502;actin cytoskeleton organization#GO:0030036;central nervous system development#GO:0007417;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000041411.1|UniProtKB=A0A2I2YH49 A0A2I2YH49 PTHR23266:SF419 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA-LIKE POLYPEPTIDE 1 binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000039792.1|UniProtKB=A0A2I2ZQY5 A0A2I2ZQY5 PTHR11885:SF17 RIBOSOMAL PROTEIN S15P/S13E SMALL RIBOSOMAL SUBUNIT PROTEIN US15 N-TERMINAL DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribosome#GO:0005840;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;cytosolic ribosome#GO:0022626;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000040368.1|UniProtKB=A0A2I2YP49 A0A2I2YP49 MPZL1 PTHR13869:SF19 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000034850.2|UniProtKB=G3SKN6 G3SKN6 VPS13B PTHR12517:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13B membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000001839.3|UniProtKB=G3RWN9 G3RWN9 EPS8L1 PTHR12287:SF19 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8-LIKE PROTEIN 1 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cell projection organization#GO:0031346;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of intracellular signal transduction#GO:1902531;regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;response to stimulus#GO:0050896 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;cell projection membrane#GO:0031253;ruffle#GO:0001726;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006858.3|UniProtKB=G3QVF1 G3QVF1 PTPRG PTHR19134:SF468 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE GAMMA phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;cell communication#GO:0007154;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;biological regulation#GO:0065007;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006744.3|UniProtKB=G3QV34 G3QV34 ITM2B PTHR10962:SF4 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2B binding#GO:0005488;peptide binding#GO:0042277 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000043881.1|UniProtKB=A0A2I2YGA2 A0A2I2YGA2 CLEC12A PTHR46490:SF4 C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000025443.2|UniProtKB=G3SIZ9 G3SIZ9 SSUH2 PTHR15852:SF54 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN PROTEIN SSUH2 HOMOLOG GORGO|Ensembl=ENSGGOG00000037479.1|UniProtKB=G3QTS4 G3QTS4 PHOSPHO2 PTHR20889:SF1 PHOSPHATASE, ORPHAN 1, 2 PYRIDOXAL PHOSPHATE PHOSPHATASE PHOSPHO2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000027051.2|UniProtKB=G3SFC6 G3SFC6 NRIP2 PTHR12917:SF17 ASPARTYL PROTEASE DDI-RELATED NUCLEAR RECEPTOR-INTERACTING PROTEIN 2 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aspartic protease#PC00053;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004374.3|UniProtKB=G3SEY7 G3SEY7 FBLN5 PTHR24034:SF107 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-5 external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000002282.3|UniProtKB=G3S6J4 G3S6J4 KISS1 PTHR16955:SF6 METASTASIS-SUPPRESSOR KISS-1 METASTASIS-SUPPRESSOR KISS-1 G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of system process#GO:0044057;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;positive regulation of signaling#GO:0023056;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of hormone secretion#GO:0046883;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000042677.1|UniProtKB=G3RP93 G3RP93 FFAR3 PTHR45822:SF6 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 3-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;biological regulation#GO:0065007;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to fatty acid#GO:0071398;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to fatty acid#GO:0070542;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000007839.3|UniProtKB=G3QXW0 G3QXW0 PTHR11451:SF38 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE 2, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000002884.3|UniProtKB=G3QK66 G3QK66 GRXCR1 PTHR46990:SF1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 1 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;sensory organ development#GO:0007423;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;inner ear development#GO:0048839;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;ear development#GO:0043583;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;inner ear receptor cell stereocilium organization#GO:0060122;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;cilium#GO:0005929;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;stereocilium#GO:0032420;membraneless organelle#GO:0043228;neuron projection#GO:0043005;intracellular membraneless organelle#GO:0043232 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000000812.3|UniProtKB=G3QEV0 G3QEV0 TDRD9 PTHR18934:SF113 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE TDRD9 helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015583.3|UniProtKB=G3RHS5 G3RHS5 PDK2 PTHR11947:SF15 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 2, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 TCA cycle#P00051>Pyruvate Dehydrogenase#P01266 GORGO|Ensembl=ENSGGOG00000009741.3|UniProtKB=G3R2Q3 G3R2Q3 TEX29 PTHR37339:SF1 TESTIS-EXPRESSED PROTEIN 29 TESTIS-EXPRESSED PROTEIN 29 GORGO|Ensembl=ENSGGOG00000010589.3|UniProtKB=A0A2I2Y1P3 A0A2I2Y1P3 LSM12 PTHR13542:SF0 LSM12 HOMOLOG PROTEIN LSM12 GORGO|Ensembl=ENSGGOG00000006532.3|UniProtKB=G3QUJ4 G3QUJ4 ERN1 PTHR13954:SF17 IRE1-RELATED SERINE_THREONINE-PROTEIN KINASE_ENDORIBONUCLEASE IRE1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;nuclease activity#GO:0004518;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519 endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;apoptotic signaling pathway#GO:0097190;programmed cell death#GO:0012501;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transmembrane signal receptor#PC00197;tyrosine protein kinase receptor#PC00233 Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110;Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144 GORGO|Ensembl=ENSGGOG00000007326.4|UniProtKB=G3QWK9 G3QWK9 COMMD10 PTHR12333:SF0 COMM DOMAIN CONTAINING PROTEIN 10 COMM DOMAIN-CONTAINING PROTEIN 10 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000002677.3|UniProtKB=A0A2I2YIS0 A0A2I2YIS0 ZNF438 PTHR24408:SF23 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 438 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003634.3|UniProtKB=A0A2I2ZVD2 A0A2I2ZVD2 TGFBR1 PTHR23255:SF61 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-1 kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;activin binding#GO:0048185;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089 response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell population proliferation#GO:0008283;response to transforming growth factor beta#GO:0071559;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;activin receptor signaling pathway#GO:0032924;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;endothelial cell proliferation#GO:0001935;epithelial cell proliferation#GO:0050673;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell surface receptor signaling pathway#GO:0007166 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;signaling receptor complex#GO:0043235;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 GORGO|Ensembl=ENSGGOG00000006054.3|UniProtKB=G3QTB0 G3QTB0 PTHR11738:SF185 MHC CLASS I NK CELL RECEPTOR PLATELET GLYCOPROTEIN VI molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of immune response#GO:0050776;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000007058.3|UniProtKB=G3S9R4 G3S9R4 SLC25A23 PTHR24089:SF196 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SLC25A23 antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;purine nucleotide transmembrane transporter activity#GO:0015216;phosphate transmembrane transporter activity#GO:0005315;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505 transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;carbohydrate derivative transport#GO:1901264;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;nitrogen compound transport#GO:0071705;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 GORGO|Ensembl=ENSGGOG00000012996.3|UniProtKB=A0A2I2YP23 A0A2I2YP23 CNOT3 PTHR23326:SF34 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007 CCR4-NOT complex#GO:0030014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004378.3|UniProtKB=G3QP17 G3QP17 ALK PTHR24416:SF276 TYROSINE-PROTEIN KINASE RECEPTOR ALK TYROSINE KINASE RECEPTOR transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of neuron differentiation#GO:0045664 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001415.3|UniProtKB=G3QGE2 G3QGE2 TSFM PTHR11741:SF0 ELONGATION FACTOR TS ELONGATION FACTOR TS, MITOCHONDRIAL translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000016615.3|UniProtKB=G3RKE1 G3RKE1 LOC101124517 PTHR26453:SF625 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014737.3|UniProtKB=G3SE83 G3SE83 PGF PTHR12025:SF9 VASCULAR ENDOTHELIAL GROWTH FACTOR PLACENTA GROWTH FACTOR receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;molecular function activator activity#GO:0140677;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;developmental process#GO:0032502;response to hypoxia#GO:0001666;positive regulation of locomotion#GO:0040017;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;tube development#GO:0035295;biological regulation#GO:0065007;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;positive regulation of chemotaxis#GO:0050921;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of leukocyte migration#GO:0002685;cell surface receptor signaling pathway#GO:0007166;positive regulation of response to external stimulus#GO:0032103;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of response to external stimulus#GO:0032101;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;blood vessel morphogenesis#GO:0048514;response to abiotic stimulus#GO:0009628;vascular endothelial growth factor receptor signaling pathway#GO:0048010;response to endogenous stimulus#GO:0009719;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000011693.3|UniProtKB=G3R7S7 G3R7S7 DUOX2 PTHR11972:SF67 NADPH OXIDASE DUAL OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 superoxide metabolic process#GO:0006801;response to stimulus#GO:0050896;defense response#GO:0006952;reactive oxygen species metabolic process#GO:0072593;response to stress#GO:0006950;metabolic process#GO:0008152;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;catalytic complex#GO:1902494 oxidase#PC00175;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000016323.3|UniProtKB=G3RYE2 G3RYE2 LAMA1 PTHR10574:SF409 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 neuron projection development#GO:0031175;sensory system development#GO:0048880;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell projection morphogenesis#GO:0048858;vasculature development#GO:0001944;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;circulatory system development#GO:0072359;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;eye development#GO:0001654;neuron development#GO:0048666;axon guidance#GO:0007411;axon development#GO:0061564;tissue development#GO:0009888;multicellular organismal process#GO:0032501;tube development#GO:0035295;plasma membrane bounded cell projection organization#GO:0120036;sensory organ development#GO:0007423;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;visual system development#GO:0150063;camera-type eye development#GO:0043010;anatomical structure development#GO:0048856;system development#GO:0048731 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000007735.3|UniProtKB=G3QXL9 G3QXL9 HDAC11 PTHR10625:SF23 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 11 catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;cellular process#GO:0009987 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000039785.1|UniProtKB=A4H1Z9 A4H1Z9 DEFB103A PTHR20515:SF0 BETA-DEFENSIN BETA-DEFENSIN 103 binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 response to external stimulus#GO:0009605;defense response#GO:0006952;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;defense response to bacterium#GO:0042742;chemotaxis#GO:0006935;response to bacterium#GO:0009617;cellular response to chemical stimulus#GO:0070887;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;locomotion#GO:0040011;response to stimulus#GO:0050896;cell motility#GO:0048870 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000039843.1|UniProtKB=A0A2I2YSJ6 A0A2I2YSJ6 BEX4 PTHR13987:SF3 PROTEIN BEX4 PROTEIN BEX4 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014357.3|UniProtKB=A0A2I2YZG2 A0A2I2YZG2 INTS6L PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6-LIKE molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;snRNA processing#GO:0016180;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;integrator complex#GO:0032039;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000003612.3|UniProtKB=G3QM26 G3QM26 PTHR24100:SF110 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 2 MEMBER A3-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000011746.3|UniProtKB=G3R7V6 G3R7V6 PTHR16537:SF1 SJOEGREN SYNDROME/SCLERODERMA AUTOANTIGEN 1 PROTEIN ZNRD2 GORGO|Ensembl=ENSGGOG00000024066.2|UniProtKB=G3RWJ4 G3RWJ4 MGAT4B PTHR12062:SF1 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000028602.2|UniProtKB=G3QKR1 G3QKR1 PGAM1 PTHR11931:SF34 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE 1 phosphoglycerate mutase activity#GO:0004619;isomerase activity#GO:0016853;intramolecular phosphotransferase activity#GO:0016868;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 isomerase#PC00135;mutase#PC00160 GORGO|Ensembl=ENSGGOG00000011900.3|UniProtKB=G3R8A6 G3R8A6 TEDC2 PTHR14870:SF1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 2 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 2 GORGO|Ensembl=ENSGGOG00000008781.3|UniProtKB=A0A2I2YEW1 A0A2I2YEW1 RCN3 PTHR10827:SF47 RETICULOCALBIN RETICULOCALBIN-3 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000038191.1|UniProtKB=A0A2I2Z6X4 A0A2I2Z6X4 POLR3H PTHR12709:SF1 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000040989.1|UniProtKB=A0A2I2YKZ5 A0A2I2YKZ5 CPA4 PTHR11705:SF136 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A4 peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000003715.3|UniProtKB=A0A2I2ZE67 A0A2I2ZE67 VCF2 PTHR34763:SF2 PROTEIN FAM104A PROTEIN VCF2 GORGO|Ensembl=ENSGGOG00000000766.3|UniProtKB=G3RQZ9 G3RQZ9 LSR PTHR15923:SF1 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN LIPOLYSIS-STIMULATED LIPOPROTEIN RECEPTOR system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell junction organization#GO:0034330;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000004410.3|UniProtKB=G3QP39 G3QP39 HARBI1 PTHR22930:SF253 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED GORGO|Ensembl=ENSGGOG00000041639.1|UniProtKB=A0A2I2ZJU8 A0A2I2ZJU8 PTHR11309:SF81 FRIZZLED FRIZZLED-1 signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Wnt signaling pathway#P00057>Frizzled#P01428;Angiogenesis#P00005>FRP#P00237;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 GORGO|Ensembl=ENSGGOG00000014146.3|UniProtKB=G3RE29 G3RE29 NIPAL4 PTHR12570:SF7 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MAGNESIUM TRANSPORTER NIPA4 magnesium ion transport#GO:0015693;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000028610.2|UniProtKB=A0A2I2ZMP5 A0A2I2ZMP5 PTHR12121:SF45 CARBON CATABOLITE REPRESSOR PROTEIN 4 NOCTURNIN hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000013867.3|UniProtKB=G3RDE5 G3RDE5 ABCA8 PTHR19229:SF274 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC-TYPE ORGANIC ANION TRANSPORTER ABCA8 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000003958.3|UniProtKB=G3QMY4 G3QMY4 ZNF575 PTHR23226:SF206 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 575 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005669.3|UniProtKB=G3QSF0 G3QSF0 EP400 PTHR46459:SF1 E1A-BINDING PROTEIN P400-RELATED E1A-BINDING PROTEIN P400 binding#GO:0005488;chromatin binding#GO:0003682 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;acetyltransferase complex#GO:1902493;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;Swr1 complex#GO:0000812;catalytic complex#GO:1902494;H4 histone acetyltransferase complex#GO:1902562;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000010448.3|UniProtKB=G3R4I6 G3R4I6 MYOZ2 PTHR15941:SF9 MYOZENIN MYOZENIN-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;molecular condensate scaffold activity#GO:0140693 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;muscle organ development#GO:0007517;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell development#GO:0048468;actomyosin structure organization#GO:0031032;response to stimulus#GO:0050896;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;striated muscle cell development#GO:0055002;skeletal muscle tissue development#GO:0007519;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;system process#GO:0003008;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;I band#GO:0031674 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000043195.1|UniProtKB=A0A2I2Y258 A0A2I2Y258 ERC1 PTHR18861:SF1 ELKS/RAB6-INTERACTING/CAST PROTEIN ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1 structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043 cell junction#GO:0030054;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cytoplasm#GO:0005737;presynapse#GO:0098793;cell cortex#GO:0005938;cell periphery#GO:0071944 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000002366.3|UniProtKB=G3RWD9 G3RWD9 CARD14 PTHR14559:SF1 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 14 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026130.2|UniProtKB=A0A2I2YCU2 A0A2I2YCU2 PTHR11599:SF204 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-3 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000036381.1|UniProtKB=G3SG80 G3SG80 ZNF578 PTHR24377:SF859 IP01015P-RELATED ZINC FINGER PROTEIN 578 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016917.3|UniProtKB=G3RL76 G3RL76 TMEM214 PTHR13448:SF0 TRANSMEMBRANE PROTEIN 214 TRANSMEMBRANE PROTEIN 214 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000024037.2|UniProtKB=G3SGW6 G3SGW6 PTHR23235:SF156 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUPPEL-LIKE FACTOR 18 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011517.3|UniProtKB=A0A2I2ZMU8 A0A2I2ZMU8 NRG3 PTHR11100:SF18 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-3, MEMBRANE-BOUND ISOFORM signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;biological regulation#GO:0065007;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;animal organ development#GO:0048513 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 EGF receptor signaling pathway#P00018>EGF#P00549 GORGO|Ensembl=ENSGGOG00000007843.3|UniProtKB=G3QXV9 G3QXV9 PTHR23001:SF17 EUKARYOTIC TRANSLATION INITIATION FACTOR TRANSLATION INITIATION FACTOR IF2_IF5 DOMAIN-CONTAINING PROTEIN translation factor activity#GO:0180051;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;GTPase regulator activity#GO:0030695;translation initiation factor binding#GO:0031369;nucleoside-triphosphatase regulator activity#GO:0060589;binding#GO:0005488;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000043404.1|UniProtKB=G3SI13 G3SI13 LOC101145063 PTHR10106:SF14 CYTOCHROME B561-RELATED TRANSMEMBRANE ASCORBATE-DEPENDENT REDUCTASE CYB561 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;carbohydrate homeostasis#GO:0033500;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000043736.1|UniProtKB=A0A2I2Y297 A0A2I2Y297 PTHR45883:SF9 HSC70-INTERACTING PROTEIN STI1 DOMAIN-CONTAINING PROTEIN protein-folding chaperone binding#GO:0051087;binding#GO:0005488;heat shock protein binding#GO:0031072;protein binding#GO:0005515;Hsp70 protein binding#GO:0030544 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 GORGO|Ensembl=ENSGGOG00000000295.3|UniProtKB=G3QDH2 G3QDH2 CLDN20 PTHR12002:SF17 CLAUDIN CLAUDIN-20 cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043 cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000005476.3|UniProtKB=G3QRU8 G3QRU8 CXCL16 PTHR14385:SF0 CXC CHEMOKINE LIGAND C-X-C MOTIF CHEMOKINE 16 cargo receptor activity#GO:0038024;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;low-density lipoprotein particle receptor activity#GO:0005041;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125 cellular process#GO:0009987;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;lymphocyte migration#GO:0072676;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;leukocyte chemotaxis#GO:0030595;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;chemotaxis#GO:0006935;mononuclear cell migration#GO:0071674;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;cell chemotaxis#GO:0060326;regulation of cell motility#GO:2000145 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;chemokine#PC00074 GORGO|Ensembl=ENSGGOG00000026946.2|UniProtKB=A0A2I2Y376 A0A2I2Y376 FSD1L PTHR24099:SF8 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FSD1-LIKE PROTEIN ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000011241.3|UniProtKB=G3R6K8 G3R6K8 NPR2 PTHR11920:SF509 GUANYLYL CYCLASE ATRIAL NATRIURETIC PEPTIDE RECEPTOR 2 peptide receptor activity#GO:0001653;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;lyase activity#GO:0016829;molecular transducer activity#GO:0060089 carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cyclic nucleotide biosynthetic process#GO:0009190;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanylate cyclase#PC00114;lyase#PC00144 Gonadotropin-releasing hormone receptor pathway#P06664>Npr2#P06796 GORGO|Ensembl=ENSGGOG00000006753.3|UniProtKB=G3QV47 G3QV47 LMAN1 PTHR12223:SF32 VESICULAR MANNOSE-BINDING LECTIN PROTEIN ERGIC-53 small molecule binding#GO:0036094;binding#GO:0005488;carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000003818.3|UniProtKB=A0A2I2Y3F2 A0A2I2Y3F2 ACER3 PTHR46187:SF3 ALKALINE CERAMIDASE 3 ALKALINE CERAMIDASE 3 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingoid biosynthetic process#GO:0046520;primary metabolic process#GO:0044238;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000010459.3|UniProtKB=A0A2I2YK27 A0A2I2YK27 CNOT8 PTHR10797:SF1 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 8 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098 regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;CCR4-NOT complex#GO:0030014;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 RNA metabolism protein#PC00031;RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000027202.2|UniProtKB=A0A2I2YSU6 A0A2I2YSU6 GIPC3 PTHR12259:SF2 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC3 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000023851.2|UniProtKB=G3SG43 G3SG43 PRAMEF20 PTHR14224:SF93 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 20 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000011017.3|UniProtKB=G3RXX3 G3RXX3 JAG1 PTHR24044:SF448 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Serrate#P01104;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Next#P01103 GORGO|Ensembl=ENSGGOG00000007435.3|UniProtKB=G3QWV7 G3QWV7 APBB2 PTHR14058:SF11 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 2 binding#GO:0005488;peptide binding#GO:0042277 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 GORGO|Ensembl=ENSGGOG00000025543.2|UniProtKB=A0A2I2ZSS8 A0A2I2ZSS8 GOLT1B PTHR21493:SF79 CGI-141-RELATED/LIPASE CONTAINING PROTEIN VESICLE TRANSPORT PROTEIN GOT1B membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000008086.3|UniProtKB=G3QYG9 G3QYG9 RAB18 PTHR47977:SF80 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-18 binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000026740.2|UniProtKB=G3SH42 G3SH42 EMC7 PTHR13605:SF4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7 ENDOPLASMIC RETICULUM MEMBRANE PROTEIN COMPLEX SUBUNIT 7 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;EMC complex#GO:0072546;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 GORGO|Ensembl=ENSGGOG00000016281.3|UniProtKB=A0A2I2YR65 A0A2I2YR65 EPHB3 PTHR46877:SF6 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 3 transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 dendrite#GO:0030425;dendritic tree#GO:0097447;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 GORGO|Ensembl=ENSGGOG00000005705.3|UniProtKB=P61140 P61140 SNCA PTHR13820:SF5 SYNUCLEIN ALPHA-SYNUCLEIN transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;copper ion binding#GO:0005507;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 cellular localization#GO:0051641;secretion by cell#GO:0032940;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;export from cell#GO:0140352;signaling#GO:0023052;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;cellular component assembly#GO:0022607;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;synaptic vesicle endocytosis#GO:0048488;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;synaptic vesicle recycling#GO:0036465;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;vesicle localization#GO:0051648 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;presynapse#GO:0098793;neuron projection#GO:0043005;cell junction#GO:0030054;axon terminus#GO:0043679;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron projection terminus#GO:0044306;neuronal cell body#GO:0043025;cell projection#GO:0042995;cell body#GO:0044297;intracellular anatomical structure#GO:0005622;axon#GO:0030424 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Parkinson disease#P00049>alpha-Synuclein#P01218 GORGO|Ensembl=ENSGGOG00000008831.3|UniProtKB=G3RT49 G3RT49 CREB3L3 PTHR45996:SF1 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 GORGO|Ensembl=ENSGGOG00000011070.4|UniProtKB=A0A2I2ZRL6 A0A2I2ZRL6 DPP6 PTHR11731:SF20 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED A-TYPE POTASSIUM CHANNEL MODULATORY PROTEIN DPP6 catalytic activity#GO:0003824;ion channel regulator activity#GO:0099106;peptidase activity#GO:0008233;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;channel regulator activity#GO:0016247;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 regulation of localization#GO:0032879;regulation of transport#GO:0051049;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of monoatomic cation transmembrane transport#GO:1904062;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;protein metabolic process#GO:0019538;proteolysis#GO:0006508;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;primary metabolic process#GO:0044238 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000042430.1|UniProtKB=A0A2I2YEE1 A0A2I2YEE1 PTHR23268:SF47 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 11-1 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000024318.2|UniProtKB=G3S403 G3S403 LRRC8E PTHR24369:SF193 ANTIGEN BSP, PUTATIVE-RELATED VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8E membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000036635.1|UniProtKB=A0A2I2YLM2 A0A2I2YLM2 PTHR22763:SF167 RING ZINC FINGER PROTEIN RING FINGER PROTEIN 145 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000042618.1|UniProtKB=A0A2I2ZJC0 A0A2I2ZJC0 PTHR11743:SF13 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL NON-SELECTIVE VOLTAGE-GATED ION CHANNEL VDAC1 gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic anion channel activity#GO:0008308 intracellular transport#GO:0046907;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial transport#GO:0006839 membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;cell periphery#GO:0071944;organelle outer membrane#GO:0031968;plasma membrane#GO:0005886;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000003286.3|UniProtKB=G3QL82 G3QL82 LMX1A PTHR24208:SF88 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1-ALPHA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010786.3|UniProtKB=G3R5E3 G3R5E3 FBXO33 PTHR20933:SF3 F-BOX ONLY PROTEIN 33 F-BOX ONLY PROTEIN 33 regulation of protein modification process#GO:0031399;regulation of protein ubiquitination#GO:0031396;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000016941.4|UniProtKB=G3RL99 G3RL99 ELMO1 PTHR12771:SF23 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 1 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;response to external stimulus#GO:0009605;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cell chemotaxis#GO:0060326;supramolecular fiber organization#GO:0097435;cellular response to chemical stimulus#GO:0070887;actin filament-based process#GO:0030029;chemotaxis#GO:0006935;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;response to stimulus#GO:0050896;locomotion#GO:0040011;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>ELMO#P00917 GORGO|Ensembl=ENSGGOG00000022879.2|UniProtKB=G3RWS0 G3RWS0 TARBP1 PTHR12029:SF11 RNA METHYLTRANSFERASE TRNA (GUANOSINE(18)-2'-O)-METHYLTRANSFERASE TARBP1 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003372.3|UniProtKB=G3QLG0 G3QLG0 RPL6 PTHR10715:SF7 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005744.3|UniProtKB=G3QSJ2 G3QSJ2 CATSPERE PTHR33722:SF3 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT EPSILON spermatid differentiation#GO:0048515;spermatid development#GO:0007286;cilium movement#GO:0003341;sexual reproduction#GO:0019953;cilium or flagellum-dependent cell motility#GO:0001539;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;sperm motility#GO:0097722;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;gamete generation#GO:0007276;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;cell maturation#GO:0048469;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;male gamete generation#GO:0048232;developmental maturation#GO:0021700;sperm capacitation#GO:0048240 membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;9+2 motile cilium#GO:0097729;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane protein complex#GO:0098797;sperm principal piece#GO:0097228;calcium channel complex#GO:0034704;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;sperm flagellum#GO:0036126;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000011552.3|UniProtKB=G3R7D1 G3R7D1 RBP5 PTHR11955:SF74 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 5 lipid binding#GO:0008289;fatty acid binding#GO:0005504;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;binding#GO:0005488 lipid transport#GO:0006869;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;lipid localization#GO:0010876 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000027370.2|UniProtKB=A0A2I2Y951 A0A2I2Y951 TSC2 PTHR10063:SF0 TUBERIN TUBERIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 negative regulation of signal transduction#GO:0009968;intracellular signaling cassette#GO:0141124;positive regulation of autophagy#GO:0010508;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of macroautophagy#GO:0016241;negative regulation of TORC1 signaling#GO:1904262;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;positive regulation of macroautophagy#GO:0016239;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GTPase-activating protein#PC00257;G-protein modulator#PC00022 p53 pathway by glucose deprivation#P04397>TSC2#P04644;p53 pathway by glucose deprivation#P04397>TSC2#G04706;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC2#P04494 GORGO|Ensembl=ENSGGOG00000010657.3|UniProtKB=G3R528 G3R528 LOC101127754 PTHR46019:SF5 BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED BPI FOLD-CONTAINING FAMILY B MEMBER 3 GORGO|Ensembl=ENSGGOG00000000178.3|UniProtKB=G3QD67 G3QD67 CDK5RAP2 PTHR46930:SF1 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 regulation of sister chromatid segregation#GO:0033045;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;spindle localization#GO:0051653;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of intracellular signal transduction#GO:1902531;establishment or maintenance of cell polarity#GO:0007163;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;cellular component assembly#GO:0022607;establishment of mitotic spindle localization#GO:0040001;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;microtubule organizing center organization#GO:0031023;negative regulation of cell cycle#GO:0045786;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;regulation of cytoskeleton organization#GO:0051493;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of cellular component organization#GO:0051129;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;negative regulation of cytoskeleton organization#GO:0051494;centriole replication#GO:0007099;organelle localization#GO:0051640;organelle assembly#GO:0070925;regulation of nuclear division#GO:0051783;regulation of signal transduction#GO:0009966;regulation of mitotic cell cycle#GO:0007346;regulation of organelle assembly#GO:1902115;regulation of mitotic nuclear division#GO:0007088;establishment of mitotic spindle orientation#GO:0000132;regulation of mitotic sister chromatid separation#GO:0010965;establishment of localization#GO:0051234;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular localization#GO:0051641;regulation of signaling#GO:0023051;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;centrosome duplication#GO:0051298;cellular component organization or biogenesis#GO:0071840;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;establishment of cell polarity#GO:0030010;negative regulation of organelle organization#GO:0010639;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of mitotic sister chromatid segregation#GO:0033047;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;establishment of spindle localization#GO:0051293;mitotic cell cycle process#GO:1903047;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;microtubule end#GO:1990752;spindle pole#GO:0000922;mitotic spindle#GO:0072686;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000022374.2|UniProtKB=G3RLZ7 G3RLZ7 PTHR10562:SF74 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 3 ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 protein sumoylation#GO:0016925;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 p53 pathway#P00059>Sumo-1 ligase#P04635 GORGO|Ensembl=ENSGGOG00000010841.3|UniProtKB=G3R5I9 G3R5I9 NAGLU PTHR12872:SF5 ALPHA-N-ACETYLGLUCOSAMINIDASE ALPHA-N-ACETYLGLUCOSAMINIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006160.3|UniProtKB=G3SBN0 G3SBN0 EPS15 PTHR11216:SF54 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;import into cell#GO:0098657;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;clathrin coat#GO:0030118;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;clathrin-coated pit#GO:0005905 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000002132.3|UniProtKB=G3QI95 G3QI95 PSEN1 PTHR10202:SF18 PRESENILIN PRESENILIN-1 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;protein metabolic process#GO:0019538;proteolysis#GO:0006508;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;membrane protein ectodomain proteolysis#GO:0006509;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;catalytic complex#GO:1902494 aspartic protease#PC00053;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098;Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Notch signaling pathway#P00045>Presenilin#P01110;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129 GORGO|Ensembl=ENSGGOG00000043471.1|UniProtKB=A0A2I2ZNZ7 A0A2I2ZNZ7 ZNF558 PTHR24381:SF80 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 558 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000015624.3|UniProtKB=G3RHW5 G3RHW5 ASPHD1 PTHR46332:SF1 ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 1 hydroxylase#PC00122;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010512.3|UniProtKB=G3R4P4 G3R4P4 LOC101149517 PTHR43917:SF9 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000007641.3|UniProtKB=G3QXE3 G3QXE3 MYO10 PTHR46049:SF2 AGAP003327-PA UNCONVENTIONAL MYOSIN-X actin binding#GO:0003779;ATP-dependent activity#GO:0140657;binding#GO:0005488;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;phosphatidylinositol phosphate binding#GO:1901981;actin filament binding#GO:0051015;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;polypeptide conformation or assembly isomerase activity#GO:0120544;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;isomerase activity#GO:0016853 localization#GO:0051179;cellular localization#GO:0051641;regulation of cell projection assembly#GO:0060491;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection organization#GO:0031344;intracellular transport#GO:0046907;transport#GO:0006810;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;establishment of localization#GO:0051234;regulation of filopodium assembly#GO:0051489;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;filopodium#GO:0030175;intracellular organelle#GO:0043229 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000010870.3|UniProtKB=G3R5L8 G3R5L8 FXYD4 PTHR14132:SF10 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 4 transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of monoatomic ion transmembrane transport#GO:0034765 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000004769.3|UniProtKB=G3SJK0 G3SJK0 ZKSCAN2 PTHR23226:SF164 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000043194.1|UniProtKB=G3R5S5 G3R5S5 LOC101137108 PTHR19944:SF43 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DO BETA CHAIN peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488;protein-containing complex binding#GO:0044877 positive regulation of cellular process#GO:0048522;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of cell adhesion#GO:0045785;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune response#GO:0050776;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of T cell activation#GO:0050863;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of multicellular organismal process#GO:0051239;positive regulation of leukocyte activation#GO:0002696;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765 major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000004797.3|UniProtKB=G3QQ39 G3QQ39 DRAP1 PTHR10252:SF163 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DR1-ASSOCIATED COREPRESSOR DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nucleic acid biosynthetic process#GO:0141187;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000022363.2|UniProtKB=A0A2I2Y3R8 A0A2I2Y3R8 PTHR11732:SF444 ALDO/KETO REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000011359.3|UniProtKB=G3R6W4 G3R6W4 PTHR12049:SF7 PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008595.3|UniProtKB=A0A2I2YBA4 A0A2I2YBA4 USP22 PTHR24006:SF721 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000037004.1|UniProtKB=A0A2I2Z2T8 A0A2I2Z2T8 PTHR21668:SF6 EIF-1A EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000013063.3|UniProtKB=G3RVR8 G3RVR8 LDB3 PTHR24240:SF72 OPSIN MELANOPSIN G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to radiation#GO:0071478;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of circadian rhythm#GO:0042752;cellular process#GO:0009987;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;detection of stimulus#GO:0051606;biological regulation#GO:0065007;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000014462.3|UniProtKB=G3REV8 G3REV8 DLL3 PTHR24044:SF308 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 3 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of Notch signaling pathway#GO:0045746;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;negative regulation of cellular process#GO:0048523;Notch signaling pathway#GO:0007219;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 intercellular signal molecule#PC00207 Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Delta#P01116 GORGO|Ensembl=ENSGGOG00000043341.1|UniProtKB=A0A2I2YV23 A0A2I2YV23 PTHR48099:SF1 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 tetrahydrofolate metabolic process#GO:0046653;metabolic process#GO:0008152;tetrahydrofolate biosynthetic process#GO:0046654;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007511.3|UniProtKB=A0A2I2Y706 A0A2I2Y706 C13H9orf153 PTHR37353:SF1 RIKEN CDNA 4921517D22 GENE RIKEN CDNA 4921517D22 GENE GORGO|Ensembl=ENSGGOG00000043039.1|UniProtKB=A0A2I2YUX0 A0A2I2YUX0 KIAA0040 PTHR40382:SF1 FAMILY NOT NAMED RIKEN CDNA 4930523C07 GENE GORGO|Ensembl=ENSGGOG00000024940.2|UniProtKB=A0A2I2Y9D1 A0A2I2Y9D1 LOC101132325 PTHR11224:SF53 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-4-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000034836.2|UniProtKB=G3SKR2 G3SKR2 AHCTF1 PTHR21583:SF8 ELYS PROTEIN PROTEIN ELYS scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008786.3|UniProtKB=A0A2I2Z4W6 A0A2I2Z4W6 TMBIM6 PTHR23291:SF133 BAX INHIBITOR-RELATED BAX INHIBITOR 1 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;cellular response to topologically incorrect protein#GO:0035967;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of signaling#GO:0023057;cellular response to unfolded protein#GO:0034620;negative regulation of cell communication#GO:0010648;response to unfolded protein#GO:0006986;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;response to topologically incorrect protein#GO:0035966;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 ion channel#PC00133;transporter#PC00227 Apoptosis signaling pathway#P00006>Bi1#P00277 GORGO|Ensembl=ENSGGOG00000004159.3|UniProtKB=G3QNG7 G3QNG7 TP53TG5 PTHR15562:SF0 TP53-TARGET GENE 5 PROTEIN TP53-TARGET GENE 5 PROTEIN GORGO|Ensembl=ENSGGOG00000040451.1|UniProtKB=A0A2I2ZFR4 A0A2I2ZFR4 CFAP276 PTHR48619:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 276 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 276 GORGO|Ensembl=ENSGGOG00000003290.3|UniProtKB=G3QL86 G3QL86 TOE1 PTHR15092:SF37 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 TARGET OF EGR1 PROTEIN 1 3'-5'-RNA exonuclease activity#GO:0000175;binding#GO:0005488;nucleic acid binding#GO:0003676;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;snRNA binding#GO:0017069;RNA binding#GO:0003723;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540 RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000008892.3|UniProtKB=G3R0K6 G3R0K6 HPS6 PTHR14696:SF2 HERMANSKY-PUDLAK SYNDROME 6 PROTEIN BLOC-2 COMPLEX MEMBER HPS6 intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;organelle localization#GO:0051640;cellular process#GO:0009987;lysosome localization#GO:0032418;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000005187.3|UniProtKB=G3QR45 G3QR45 CLCC1 PTHR34093:SF1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509 monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;calcium ion homeostasis#GO:0055074;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006977.4|UniProtKB=G3QVP7 G3QVP7 DCAF10 PTHR14588:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 10 DDB1- AND CUL4-ASSOCIATED FACTOR 10 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 GORGO|Ensembl=ENSGGOG00000016305.3|UniProtKB=A0A2I2Z5A1 A0A2I2Z5A1 HTR7 PTHR24247:SF116 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 7 transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Gene=RAX2|UniProtKB=A1YEV8 A1YEV8 RAX2 PTHR46271:SF2 HOMEOBOX PROTEIN, PUTATIVE-RELATED RETINA AND ANTERIOR NEURAL FOLD HOMEOBOX PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000005674.3|UniProtKB=A0A2I2YZL2 A0A2I2YZL2 ABCC11 PTHR24223:SF168 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 11 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;bile acid and bile salt transport#GO:0015721 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000038683.1|UniProtKB=A0A2I2YMD6 A0A2I2YMD6 PTHR13544:SF0 SELENOPROTEIN T THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036 cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 GORGO|Ensembl=ENSGGOG00000009817.3|UniProtKB=G3R2X4 G3R2X4 SOSTDC1 PTHR14903:SF5 SCLEROSTIN-RELATED SCLEROSTIN DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;cytokine binding#GO:0019955;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of BMP signaling pathway#GO:0030510;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000023025.2|UniProtKB=G3SGA6 G3SGA6 RAF1 PTHR23257:SF763 SERINE-THREONINE PROTEIN KINASE RAF PROTO-ONCOGENE SERINE_THREONINE-PROTEIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000044170.1|UniProtKB=A0A2I2YGZ8 A0A2I2YGZ8 PTHR46559:SF4 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 PROTEIN TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 11 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;receptor tyrosine kinase binding#GO:0030971;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;phosphoric ester hydrolase activity#GO:0042578;cell adhesion molecule binding#GO:0050839 positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000003641.3|UniProtKB=G3QM53 G3QM53 B4GALT2 PTHR19300:SF32 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 2 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000000051.3|UniProtKB=A0A2I2ZV71 A0A2I2ZV71 DNAJC17 PTHR44313:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular component disassembly#GO:0022411;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex disassembly#GO:0032984;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000007358.3|UniProtKB=G3RP59 G3RP59 SEC11C PTHR10806:SF12 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11C catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;peptidase complex#GO:1905368;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827 serine protease#PC00203 Vasopressin synthesis#P04395>Signal Peptidase#P04589;Endothelin signaling pathway#P00019>signal peptidase#P00573 GORGO|Ensembl=ENSGGOG00000007544.3|UniProtKB=G3QX55 G3QX55 SLC6A19 PTHR11616:SF125 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 apical part of cell#GO:0045177;cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862;apical plasma membrane#GO:0016324;membrane#GO:0016020;brush border#GO:0005903;cell periphery#GO:0071944;plasma membrane region#GO:0098590;brush border membrane#GO:0031526;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 GORGO|Ensembl=ENSGGOG00000024985.2|UniProtKB=G3RUQ5 G3RUQ5 PTHR14132:SF12 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA PHOSPHOLEMMAN transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of monoatomic ion transmembrane transport#GO:0034765;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of transmembrane transport#GO:0034762;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of localization#GO:0032879;regulation of transport#GO:0051049 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023972.2|UniProtKB=G3SFM4 G3SFM4 IRF2BP1 PTHR10816:SF17 MYELIN TRANSCRIPTION FACTOR 1-RELATED INTERFERON REGULATORY FACTOR 2-BINDING PROTEIN 1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000001585.3|UniProtKB=G3QGU9 G3QGU9 EBF2 PTHR10747:SF33 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;P53-like transcription factor#PC00253 GORGO|Ensembl=ENSGGOG00000024748.2|UniProtKB=G3SB59 G3SB59 PROB1 PTHR33775:SF1 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED PROLINE-RICH BASIC PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000016096.3|UniProtKB=G3RJ28 G3RJ28 PTHR17045:SF7 MELANOCYTE SPECIFIC GENE RELATED CITED CBP_P300-INTERACTING TRANSACTIVATOR 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;transforming growth factor beta receptor signaling pathway#GO:0007179;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to growth factor stimulus#GO:0071363;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;response to transforming growth factor beta#GO:0071559 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 GORGO|Ensembl=ENSGGOG00000007345.3|UniProtKB=G3QWN0 G3QWN0 SP9 PTHR23235:SF26 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP9 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015973.3|UniProtKB=G3S1Z2 G3S1Z2 DHRS13 PTHR43157:SF44 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 13 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000038602.1|UniProtKB=A0A2I2ZHG0 A0A2I2ZHG0 SPMIP1 PTHR35826:SF2 PROTEIN ATP6V1FNB-LIKE PROTEIN SPMIP1 GORGO|Ensembl=ENSGGOG00000010244.3|UniProtKB=G3R406 G3R406 LOC101152943 PTHR48018:SF129 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9G4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015131.3|UniProtKB=G3RGL8 G3RGL8 CPSF4 PTHR23102:SF18 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000038709.1|UniProtKB=A0A2I2YS15 A0A2I2YS15 PTHR12126:SF9 NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL binding#GO:0005488;protein-containing complex binding#GO:0044877 ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005606.3|UniProtKB=G3QS64 G3QS64 ENO2 PTHR11902:SF10 ENOLASE GAMMA-ENOLASE catalytic activity#GO:0003824;phosphopyruvate hydratase activity#GO:0004634;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nicotinamide nucleotide metabolic process#GO:0046496;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117 catalytic complex#GO:1902494;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;lyase#PC00144 Glycolysis#P00024>Enolase#P00678 GORGO|Ensembl=ENSGGOG00000027897.2|UniProtKB=G3RPA6 G3RPA6 PTHR24103:SF575 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 64C ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 immune system process#GO:0002376;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012370.3|UniProtKB=G3R9J0 G3R9J0 CDH9 PTHR24027:SF99 CADHERIN-23 CADHERIN-9 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell motility#GO:0048870;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;synapse organization#GO:0050808;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;synaptic membrane adhesion#GO:0099560;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell migration#GO:0016477;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000002700.3|UniProtKB=G3QJQ8 G3QJQ8 HSPB1 PTHR45640:SF7 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-1 response to stress#GO:0006950;response to heat#GO:0009408;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;protein folding#GO:0006457;protein metabolic process#GO:0019538;protein refolding#GO:0042026 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 chaperone#PC00072 p38 MAPK pathway#P05918>HSP27#P06016;VEGF signaling pathway#P00056>HSP27#P01412;CCKR signaling map#P06959>HSP27#P07154;Angiogenesis#P00005>HSP27#P00231 GORGO|Ensembl=ENSGGOG00000013198.3|UniProtKB=A0A2I2ZB77 A0A2I2ZB77 RXFP1 PTHR24372:SF68 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000002534.3|UniProtKB=G3SBY3 G3SBY3 ZNF354A PTHR24377:SF146 IP01015P-RELATED ZINC FINGER PROTEIN 354A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014377.3|UniProtKB=G3REQ0 G3REQ0 PTHR21646:SF76 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 32 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824 positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of TORC1 signaling#GO:1904263;regulation of protein stability#GO:0031647;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of TOR signaling#GO:0032006;regulation of TORC1 signaling#GO:1903432;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of biological quality#GO:0065008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000006461.3|UniProtKB=G3QUC7 G3QUC7 PFKM PTHR13697:SF59 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE phosphotransferase activity, alcohol group as acceptor#GO:0016773;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;carbohydrate kinase activity#GO:0019200;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;transferase activity#GO:0016740 ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase#PC00137;carbohydrate kinase#PC00065;transferase#PC00220 Glycolysis#P00024>Phosphofructokinase-1#P00672 GORGO|Ensembl=ENSGGOG00000006261.3|UniProtKB=G3QTU0 G3QTU0 KLHL38 PTHR24412:SF462 KELCH PROTEIN KELCH-LIKE PROTEIN 38 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005944.3|UniProtKB=G3QT12 G3QT12 CKAP2 PTHR16076:SF8 CYTOSKELETON ASSOCIATED PROTEIN 2-RELATED CYTOSKELETON-ASSOCIATED PROTEIN 2 regulation of protein-containing complex disassembly#GO:0043244;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein depolymerization#GO:1901880;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of microtubule-based process#GO:0032886;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000002379.3|UniProtKB=G3QIX2 G3QIX2 HGH1 PTHR13387:SF9 PROTEIN HGH1 HOMOLOG CO-CHAPERONE PROTEIN HGH1 HOMOLOG GORGO|Ensembl=ENSGGOG00000036966.1|UniProtKB=G3RQ20 G3RQ20 OR6C1 PTHR26454:SF27 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025021.2|UniProtKB=A0A2I2Y7Q0 A0A2I2Y7Q0 TOMM7 PTHR46722:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of protein localization#GO:0032880 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane translocase complex#GO:0005742 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000016975.3|UniProtKB=G3RLC3 G3RLC3 PTHR10872:SF4 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 2 molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune system process#GO:0002376 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014640.3|UniProtKB=G3SF04 G3SF04 PLEKHG5 PTHR13217:SF11 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 5 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 cell motility#GO:0048870;endothelial cell migration#GO:0043542;cell migration#GO:0016477;cellular process#GO:0009987 vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000025808.2|UniProtKB=A0A2I2YJS5 A0A2I2YJS5 PTHR15341:SF3 SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA processing#GO:0006396;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000015753.3|UniProtKB=A0A2I2YB19 A0A2I2YB19 FKBP6 PTHR46674:SF1 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 binding#GO:0005488;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;protein binding#GO:0005515 cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;male gamete generation#GO:0048232;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;spermatogenesis#GO:0007283;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;sexual reproduction#GO:0019953;piRNA processing#GO:0034587;multicellular organismal reproductive process#GO:0048609 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000039759.1|UniProtKB=A0A2I2YCI0 A0A2I2YCI0 PTHR23143:SF19 TRICHOHYALIN-RELATED GOLGIN A6 FAMILY LIKE 10-RELATED actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000010676.3|UniProtKB=G3RPY8 G3RPY8 FBXO21 PTHR31350:SF21 SI:DKEY-261L7.2 F-BOX ONLY PROTEIN 21 GORGO|Ensembl=ENSGGOG00000009751.3|UniProtKB=G3R2R7 G3R2R7 SYN2 PTHR10841:SF20 SYNAPSIN SYNAPSIN-2 cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>Synapsin#P05775 GORGO|Ensembl=ENSGGOG00000011188.3|UniProtKB=A0A2I2Y987 A0A2I2Y987 ADCY2 PTHR45627:SF6 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 2 cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;Beta2 adrenergic receptor signaling pathway#P04378>AC#P04446;Opioid proopiomelanocortin pathway#P05917>AC#P06011;Enkephalin release#P05913>AC#P05978;Nicotine pharmacodynamics pathway#P06587>ADCY2#P06606;5HT1 type receptor mediated signaling pathway#P04373>AC#P04406;Beta1 adrenergic receptor signaling pathway#P04377>AC#P04439;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Histamine H2 receptor mediated signaling pathway#P04386>AC#P04492;5HT4 type receptor mediated signaling pathway#P04376>AC#P04429;Opioid proenkephalin pathway#P05915>AC#P05993;Beta3 adrenergic receptor signaling pathway#P04379>AC#P04450;Opioid prodynorphin pathway#P05916>AC#P06001;Dopamine receptor mediated signaling pathway#P05912>AC#P05947;GABA-B receptor II signaling#P05731>AC#P05760 GORGO|Ensembl=ENSGGOG00000023185.2|UniProtKB=G3RPV0 G3RPV0 LOC101124317 PTHR11905:SF232 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 20 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000007352.3|UniProtKB=A0A2I2Y672 A0A2I2Y672 ZNF425 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010674.4|UniProtKB=A0A2I2Y8M5 A0A2I2Y8M5 PLCB1 PTHR10336:SF12 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-1 lipase activity#GO:0016298;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;calmodulin binding#GO:0005516;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;signal transduction#GO:0007165;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;metabolic process#GO:0008152;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;cognition#GO:0050890;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;system process#GO:0003008;establishment of localization#GO:0051234;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;transport#GO:0006810 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 lipase#PC00143;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;CCKR signaling map#P06959>PLC_beta#P07110;Gonadotropin-releasing hormone receptor pathway#P06664>PLCbeta#P06705;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;Endogenous cannabinoid signaling#P05730>PLC#P05746;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Endothelin signaling pathway#P00019>PLCbeta#P00591;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744 GORGO|Ensembl=ENSGGOG00000003492.3|UniProtKB=G3QLR6 G3QLR6 WFS1 PTHR13098:SF3 WOLFRAMIN WOLFRAMIN biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;signal transduction#GO:0007165;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;homeostatic process#GO:0042592;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;calcium ion homeostasis#GO:0055074;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;inorganic ion homeostasis#GO:0098771;cellular response to stress#GO:0033554 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000015968.3|UniProtKB=G3RIR2 G3RIR2 CSNK1G3 PTHR11909:SF151 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 GORGO|Ensembl=ENSGGOG00000010671.3|UniProtKB=G3R545 G3R545 CABLES1 PTHR22896:SF1 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CDK5 AND ABL1 ENZYME SUBSTRATE 1 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000008634.3|UniProtKB=G3QZX1 G3QZX1 PPP4C PTHR45619:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 CATALYTIC SUBUNIT phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 GORGO|Ensembl=ENSGGOG00000016169.3|UniProtKB=G3RJ96 G3RJ96 HIVEP1 PTHR45944:SF3 SCHNURRI, ISOFORM F ZINC FINGER PROTEIN 40 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004600.3|UniProtKB=G3QPL0 G3QPL0 BAMBI PTHR15505:SF1 RIIA DOMAIN-CONTAINING PROTEIN 1 BMP AND ACTIVIN MEMBRANE-BOUND INHIBITOR HOMOLOG TGF-beta signaling pathway#P00052>BAMBI#P01287 GORGO|Ensembl=ENSGGOG00000041854.1|UniProtKB=A0A2I2Z389 A0A2I2Z389 RHBDD1 PTHR43066:SF14 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 4 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to unfolded protein#GO:0006986 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000026926.2|UniProtKB=A0A2I2ZFZ2 A0A2I2ZFZ2 TRPC1 PTHR10117:SF56 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 1 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488 homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 GORGO|Ensembl=ENSGGOG00000012837.3|UniProtKB=G3RAP1 G3RAP1 NANP PTHR46470:SF3 N-ACYLNEURAMINATE-9-PHOSPHATASE N-ACYLNEURAMINATE-9-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000023860.2|UniProtKB=G3S5P7 G3S5P7 NUDT6 PTHR13994:SF46 NUDIX HYDROLASE RELATED NUDIX HYDROLASE 6 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity#GO:0016787 nucleotide phosphatase#PC00173;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000025197.2|UniProtKB=G3S0D5 G3S0D5 NENF PTHR10281:SF120 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUDESIN growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043756.1|UniProtKB=A0A2I2ZFK6 A0A2I2ZFK6 LOC109025072 PTHR24012:SF745 RNA BINDING PROTEIN RRM DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010128.3|UniProtKB=G3R3Q4 G3R3Q4 NT5C3B PTHR13045:SF15 5'-NUCLEOTIDASE 7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;esterase#PC00097 GORGO|Ensembl=ENSGGOG00000038981.1|UniProtKB=A0A2I2YFG4 A0A2I2YFG4 PTHR23266:SF305 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000004691.3|UniProtKB=G3RYV8 G3RYV8 TTC29 PTHR46630:SF2 TETRATRICOPEPTIDE REPEAT PROTEIN 29 TETRATRICOPEPTIDE REPEAT PROTEIN 29 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cilium movement#GO:0003341;cellular process#GO:0009987 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000043462.1|UniProtKB=A0A2I2Z5H7 A0A2I2Z5H7 PTHR23267:SF468 IMMUNOGLOBULIN LIGHT CHAIN NON-FUNCTIONAL IMMUNOGLOBULIN KAPPA VARIABLE 1-37-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015451.3|UniProtKB=G3RHG0 G3RHG0 PTHR21328:SF23 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP6 protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;transferase activity#GO:0016740;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;molecular function regulator activity#GO:0098772;glycosyltransferase activity#GO:0016757;protein kinase activator activity#GO:0030295;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;kinase activator activity#GO:0019209 endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052 endoplasmic reticulum#GO:0005783;endoplasmic reticulum tubular network#GO:0071782;nucleus#GO:0005634;membrane#GO:0016020;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009129.3|UniProtKB=G3R166 G3R166 PTHR13675:SF3 LYR MOTIF-CONTAINING PROTEIN 2 LYR MOTIF-CONTAINING PROTEIN 2 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000004796.3|UniProtKB=A0A2I2Y799 A0A2I2Y799 PORCN PTHR13906:SF12 PORCUPINE PROTEIN-SERINE O-PALMITOLEOYLTRANSFERASE PORCUPINE protein binding#GO:0005515;Wnt-protein binding#GO:0017147;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;binding#GO:0005488;transferase activity#GO:0016740 protein localization to extracellular region#GO:0071692;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;signaling#GO:0023052;export from cell#GO:0140352;signal release#GO:0023061;protein transport#GO:0015031;secretion by cell#GO:0032940;secretion#GO:0046903;localization#GO:0051179;protein secretion#GO:0009306;cell communication#GO:0007154;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;transport#GO:0006810;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;lipid modification#GO:0030258 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000004230.3|UniProtKB=G3RXG9 G3RXG9 ARIH1 PTHR11685:SF475 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000028407.2|UniProtKB=G3SHA0 G3SHA0 TAF1D PTHR14562:SF3 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000022785.2|UniProtKB=A0A2I2YWI1 A0A2I2YWI1 NIP7 PTHR23415:SF34 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 HOMOLOG cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015457.3|UniProtKB=G3RHF9 G3RHF9 RASSF7 PTHR15286:SF11 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006916.3|UniProtKB=A0A2I2Z9A1 A0A2I2Z9A1 ANKRD17 PTHR23206:SF1 MASK PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 17 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000580.3|UniProtKB=G3QE83 G3QE83 PER3 PTHR11269:SF13 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 3 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription factor binding#GO:0008134 rhythmic process#GO:0048511;negative regulation of DNA-templated transcription#GO:0045892;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;photoperiodism#GO:0009648;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;response to radiation#GO:0009314;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Circadian clock system#P00015>per#G01499;Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>Per#P00504 GORGO|Ensembl=ENSGGOG00000016704.3|UniProtKB=G3RKM6 G3RKM6 EXOC3L4 PTHR21292:SF14 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN 4 SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515 secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 cytoplasm#GO:0005737;exocyst#GO:0000145;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000003812.3|UniProtKB=A0A2I2YHE6 A0A2I2YHE6 KCNJ6 PTHR11767:SF19 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 2 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 GORGO|Ensembl=ENSGGOG00000034952.2|UniProtKB=G3SKN5 G3SKN5 DOCK2 PTHR45653:SF6 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 2 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146;myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;cell motility#GO:0048870;cell migration#GO:0016477;muscle structure development#GO:0061061;cell differentiation#GO:0030154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000027086.2|UniProtKB=A0A2I2ZDX1 A0A2I2ZDX1 PRKACB PTHR24353:SF116 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT BETA protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GABA-B receptor II signaling#P05731>PKA#P05752;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Endothelin signaling pathway#P00019>PKA#P00570;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;CCKR signaling map#P06959>PKA-Calpha/beta/gamma#P07099 GORGO|Ensembl=ENSGGOG00000012408.3|UniProtKB=A0A2I2ZVI3 A0A2I2ZVI3 PTHR23358:SF4 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET3 catalytic activity, acting on DNA#GO:0140097;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013892.3|UniProtKB=A0A2I2ZIJ0 A0A2I2ZIJ0 BLOC1S6 PTHR31328:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;establishment of vesicle localization#GO:0051650;cellular pigmentation#GO:0033059;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;establishment of organelle localization#GO:0051656;pigmentation#GO:0043473;organelle localization#GO:0051640;localization#GO:0051179;cellular localization#GO:0051641 actomyosin#GO:0042641;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle#GO:0030133;stress fiber#GO:0001725;cytoskeleton#GO:0005856;cell-cell contact zone#GO:0044291;intracellular protein-containing complex#GO:0140535;neuromuscular junction#GO:0031594;membraneless organelle#GO:0043228;cell junction#GO:0030054;vesicle#GO:0031982;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;BLOC-1 complex#GO:0031083;actin filament bundle#GO:0032432 GORGO|Ensembl=ENSGGOG00000002849.3|UniProtKB=G3QK38 G3QK38 PLS1 PTHR19961:SF27 FIMBRIN/PLASTIN PLASTIN-1 molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000010875.3|UniProtKB=G3SCL8 G3SCL8 CSE1L PTHR10997:SF8 IMPORTIN-7, 8, 11 EXPORTIN-2 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;protein localization to organelle#GO:0033365 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;organelle envelope#GO:0031967 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013400.3|UniProtKB=G3RC49 G3RC49 MRPS2 PTHR12534:SF0 30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR SMALL RIBOSOMAL SUBUNIT PROTEIN US2M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010556.3|UniProtKB=G3R4U1 G3R4U1 ILVBL PTHR18968:SF166 THIAMINE PYROPHOSPHATE ENZYMES 2-HYDROXYACYL-COA LYASE 2 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;catalytic activity#GO:0003824;transferase activity#GO:0016740;transketolase or transaldolase activity#GO:0016744;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 proteinogenic amino acid biosynthetic process#GO:0170038;branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234 ligase#PC00142;metabolite interconversion enzyme#PC00262 Valine biosynthesis#P02785>Acetolactate synthase#P03216;Isoleucine biosynthesis#P02748>Acetolactate synthase#P02997 GORGO|Ensembl=ENSGGOG00000015020.3|UniProtKB=A0A2I2YKU2 A0A2I2YKU2 RELCH PTHR32059:SF2 RAB11-BINDING PROTEIN RELCH RAB11-BINDING PROTEIN RELCH transport#GO:0006810;lipid localization#GO:0010876;intracellular transport#GO:0046907;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;cellular localization#GO:0051641;sterol transport#GO:0015918;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869 trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 GORGO|Ensembl=ENSGGOG00000043322.1|UniProtKB=A0A2I2YXH1 A0A2I2YXH1 PTHR16052:SF4 TBCC DOMAIN-CONTAINING PROTEIN 1 TBCC DOMAIN-CONTAINING PROTEIN 1 cellular process#GO:0009987;organelle localization#GO:0051640;centrosome localization#GO:0051642;cellular localization#GO:0051641;localization#GO:0051179 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000012242.3|UniProtKB=G3R965 G3R965 IL10RB PTHR20859:SF50 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-10 RECEPTOR SUBUNIT BETA molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866;Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 GORGO|Ensembl=ENSGGOG00000040239.1|UniProtKB=A0A2I2Z0Z1 A0A2I2Z0Z1 MGP PTHR10109:SF0 MATRIX GLA PROTEIN MATRIX GLA PROTEIN extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000024879.2|UniProtKB=G3S6V8 G3S6V8 SAR1A PTHR45684:SF6 RE74312P SMALL COPII COAT GTPASE SAR1A hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;coated membrane#GO:0048475;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000007194.3|UniProtKB=G3QW89 G3QW89 FAM24A PTHR35860:SF1 PROTEIN FAM24B PROTEIN FAM24A GORGO|Ensembl=ENSGGOG00000007559.3|UniProtKB=A0A2I2YDF6 A0A2I2YDF6 ASCC1 PTHR13360:SF1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000025407.2|UniProtKB=G3RRP5 G3RRP5 PREX2 PTHR22829:SF1 DEP DOMAIN PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 2 PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function inhibitor activity#GO:0140678;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase inhibitor activity#GO:0019210;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000028231.2|UniProtKB=G3S412 G3S412 LOC101151678 PTHR24300:SF406 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2B6 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;tetrapyrrole binding#GO:0046906;binding#GO:0005488 xenobiotic metabolic process#GO:0006805;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;arachidonate metabolic process#GO:0019369;cellular response to stimulus#GO:0051716;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 Bupropion degradation#P05729>Cytochrome P450 2B6#P05742 GORGO|Ensembl=ENSGGOG00000004706.4|UniProtKB=G3QPV6 G3QPV6 SMAD2 PTHR13703:SF42 SMAD SMAD FAMILY MEMBER 2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of transcription by RNA polymerase II#GO:0045944;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor signaling pathway#GO:0007179;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;activin receptor signaling pathway#GO:0032924;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;response to BMP#GO:0071772;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;response to transforming growth factor beta#GO:0071559;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;BMP signaling pathway#GO:0030509;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 GORGO|Ensembl=ENSGGOG00000015382.3|UniProtKB=G3RH88 G3RH88 PTHR15527:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane translocase complex#GO:0005742;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000024942.2|UniProtKB=G3RW27 G3RW27 LOC101143885 PTHR10502:SF133 ANNEXIN ANNEXIN A8-RELATED lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;ion binding#GO:0043167;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;anion binding#GO:0043168;binding#GO:0005488 endosomal transport#GO:0016197;endosome organization#GO:0007032;vesicle organization#GO:0016050;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;sarcolemma#GO:0042383;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000008177.3|UniProtKB=G3QYQ4 G3QYQ4 ILDR2 PTHR15923:SF0 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING RECEPTOR 2 animal organ development#GO:0048513;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;pancreas development#GO:0031016;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000016603.3|UniProtKB=G3RKD0 G3RKD0 RRP15 PTHR13245:SF14 RRP15-LIKE PROTEIN RRP15-LIKE PROTEIN ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 GORGO|Ensembl=ENSGGOG00000023578.2|UniProtKB=A0A2I2YM80 A0A2I2YM80 LOC101148853 PTHR11588:SF53 TUBULIN TUBULIN ALPHA-4A CHAIN structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 cell cycle#GO:0007049;cellular component organization#GO:0016043;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;microtubule-based process#GO:0007017;neurogenesis#GO:0022008 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630 tubulin#PC00228;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000000864.3|UniProtKB=G3QEZ2 G3QEZ2 CDNF PTHR12990:SF9 ARMET-LIKE PROTEIN CEREBRAL DOPAMINE NEUROTROPHIC FACTOR signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000028548.2|UniProtKB=G3RU97 G3RU97 PTHR11524:SF13 60S RIBOSOMAL PROTEIN L7 RIBOSOMAL PROTEIN UL30-LIKE nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009379.3|UniProtKB=G3R1T2 G3R1T2 XKR6 PTHR16024:SF9 XK-RELATED PROTEIN XK-RELATED PROTEIN 6 cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657;membrane invagination#GO:0010324;endomembrane system organization#GO:0010256;cellular process#GO:0009987;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;endocytosis#GO:0006897;cellular component organization#GO:0016043;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;phagocytosis#GO:0006909;developmental process#GO:0032502;transport#GO:0006810;lipid transport#GO:0006869;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;macromolecule localization#GO:0033036;localization#GO:0051179;anatomical structure development#GO:0048856;organophosphate ester transport#GO:0015748;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;programmed cell death#GO:0012501;cell death#GO:0008219 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000003049.3|UniProtKB=G3QKM1 G3QKM1 PTHR22957:SF686 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN GROWTH HORMONE-REGULATED TBC PROTEIN 1 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000009135.3|UniProtKB=G3R175 G3R175 B4GALT1 PTHR19300:SF5 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000042716.1|UniProtKB=A0A2I2ZA04 A0A2I2ZA04 PTHR16073:SF11 DCR DOMAIN-CONTAINING PROTEIN SAP DOMAIN-CONTAINING PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000016811.3|UniProtKB=G3RKW6 G3RKW6 KLHL31 PTHR45632:SF17 LD33804P KELCH-LIKE PROTEIN 31 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of JNK cascade#GO:0046328;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;negative regulation of intracellular signal transduction#GO:1902532;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;negative regulation of MAPK cascade#GO:0043409 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026545.2|UniProtKB=G3SJ95 G3SJ95 PTHR24327:SF70 HOMEOBOX PROTEIN HOMEOBOX DOMAIN-CONTAINING PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;stem cell population maintenance#GO:0019827;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;maintenance of cell number#GO:0098727;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000010737.3|UniProtKB=A0A2I2ZF06 A0A2I2ZF06 EXT2 PTHR11062:SF381 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-2 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000043850.1|UniProtKB=A0A2I2ZHF7 A0A2I2ZHF7 VSIG8 PTHR45166:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 8 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 8 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000022332.2|UniProtKB=G3RP32 G3RP32 PTHR23430:SF442 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004158.3|UniProtKB=A0A2I2Z365 A0A2I2Z365 PTHR23045:SF11 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A LRRC37A3 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037942.1|UniProtKB=A0A2I2ZFE6 A0A2I2ZFE6 ESYT1 PTHR45761:SF3 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-1 lipid binding#GO:0008289;cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylcholine binding#GO:0031210;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000008598.3|UniProtKB=A0A2I2ZEV3 A0A2I2ZEV3 HELQ PTHR47961:SF12 DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED HELICASE POLQ-LIKE helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;double-strand break repair via single-strand annealing#GO:0045002;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000012952.3|UniProtKB=G3RYM1 G3RYM1 ZSCAN18 PTHR23226:SF157 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 18 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002270.3|UniProtKB=G3QIM4 G3QIM4 SKIC2 PTHR12131:SF34 ATP-DEPENDENT RNA AND DNA HELICASE SUPERKILLER COMPLEX PROTEIN 2 ATP-dependent activity#GO:0140657;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724 macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000014008.3|UniProtKB=A0A2I2Z5H5 A0A2I2Z5H5 COL5A2 PTHR24023:SF1135 COLLAGEN ALPHA COLLAGEN ALPHA-2(V) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 skin development#GO:0043588;cellular process#GO:0009987;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000004618.3|UniProtKB=G3QPM8 G3QPM8 CDKN2D PTHR24201:SF7 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR D cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 p53 pathway#P00059>ARF#P01482;p53 pathway#P00059>ARF#G01574 GORGO|Ensembl=ENSGGOG00000034846.2|UniProtKB=A0A2I2ZH36 A0A2I2ZH36 TEX11 PTHR38487:SF1 TESTIS EXPRESSED 11 PROTEIN ZIP4 HOMOLOG GORGO|Ensembl=ENSGGOG00000036620.1|UniProtKB=G3RY32 G3RY32 SLCO1B3 PTHR11388:SF163 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804;bile acid transmembrane transporter activity#GO:0015125 lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;bile acid and bile salt transport#GO:0015721;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;lipid localization#GO:0010876 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000036483.1|UniProtKB=A0A2I2YYG6 A0A2I2YYG6 HMGA2 PTHR46254:SF6 PROTEIN GVQW1-RELATED HIGH MOBILITY GROUP AT-HOOK 2 GORGO|Ensembl=ENSGGOG00000006764.4|UniProtKB=A0A2I2YTS0 A0A2I2YTS0 JAM3 PTHR44598:SF2 JUNCTIONAL ADHESION MOLECULE C JUNCTIONAL ADHESION MOLECULE C cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000003919.3|UniProtKB=G3QMU7 G3QMU7 SLC38A8 PTHR22950:SF226 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 38 MEMBER 8 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;amino acid transport#GO:0006865;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000044044.1|UniProtKB=A0A2I2YQR0 A0A2I2YQR0 PTHR48637:SF1 SECRETED PROTEIN-RELATED CHROMOSOME 14 OPEN READING FRAME 178 GORGO|Ensembl=ENSGGOG00000002388.3|UniProtKB=G3QIX7 G3QIX7 TXLNG PTHR16127:SF14 TAXILIN GAMMA-TAXILIN regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000016789.3|UniProtKB=G3RKV1 G3RKV1 ZBTB32 PTHR24394:SF76 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 32 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000022605.2|UniProtKB=A0A2I2YMC2 A0A2I2YMC2 PTHR46559:SF5 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 PROTEIN-TYROSINE-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;receptor tyrosine kinase binding#GO:0030971;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782 regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of intracellular signal transduction#GO:1902531;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000011016.3|UniProtKB=A0A2I2ZPX1 A0A2I2ZPX1 SUDS3 PTHR21964:SF34 BREAST CANCER METASTASIS-SUPPRESSOR 1 SIN3 HISTONE DEACETYLASE COREPRESSOR COMPLEX COMPONENT SDS3 histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000007937.3|UniProtKB=G3S2K9 G3S2K9 PDZD4 PTHR15545:SF4 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 PDZ DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000006136.3|UniProtKB=G3S5X3 G3S5X3 AGTRAP PTHR16521:SF3 TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN regulation of blood pressure#GO:0008217;circulatory system process#GO:0003013;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;system process#GO:0003008;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005854.3|UniProtKB=G3QST5 G3QST5 TRAF6 PTHR10131:SF131 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 6 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;molecular adaptor activity#GO:0060090;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;signaling adaptor activity#GO:0035591;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;protein-macromolecule adaptor activity#GO:0030674;acyltransferase activity#GO:0016746 cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to lipid#GO:0033993;defense response to other organism#GO:0098542;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response#GO:0006955;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;defense response#GO:0006952;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;innate immune response#GO:0045087;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617;cell communication#GO:0007154 side of membrane#GO:0098552;cell junction#GO:0030054;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TRAF6#P01371;CCKR signaling map#P06959>TRAF6#P07111;p38 MAPK pathway#P05918>TRAF6#P06038 GORGO|Ensembl=ENSGGOG00000000834.3|UniProtKB=G3QEW7 G3QEW7 LGI3 PTHR24367:SF10 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 3 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of secretion#GO:0051046;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157 cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708 GORGO|Ensembl=ENSGGOG00000039327.1|UniProtKB=A0A2I2ZXZ9 A0A2I2ZXZ9 LOC101149269 PTHR10634:SF129 AN1-TYPE ZINC FINGER PROTEIN ZFAND5 GORGO|Ensembl=ENSGGOG00000016452.3|UniProtKB=G3RJZ6 G3RJZ6 C5AR2 PTHR24225:SF1 CHEMOTACTIC RECEPTOR C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR 2 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006856.3|UniProtKB=G3QVE6 G3QVE6 ADA PTHR11409:SF53 ADENOSINE DEAMINASE ADENOSINE DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;leukocyte activation#GO:0045321;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;purine nucleoside metabolic process#GO:0042278;cell activation#GO:0001775;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;regulation of circadian rhythm#GO:0042752;multicellular organismal process#GO:0032501;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;small molecule biosynthetic process#GO:0044283;nucleobase metabolic process#GO:0009112;T cell activation#GO:0042110;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;purine-containing compound biosynthetic process#GO:0072522;immune system process#GO:0002376;nucleoside catabolic process#GO:0009164;cellular process#GO:0009987;adenosine metabolic process#GO:0046085;lymphocyte activation#GO:0046649;regulation of multicellular organismal process#GO:0051239;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 deaminase#PC00088 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 GORGO|Ensembl=ENSGGOG00000025809.2|UniProtKB=G3S126 G3S126 PRPS1L1 PTHR10210:SF112 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000028140.2|UniProtKB=A0A2I2Y2S0 A0A2I2Y2S0 RPL10A PTHR23105:SF186 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000000597.3|UniProtKB=G3S0Y5 G3S0Y5 PTHR23285:SF5 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3B RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008787.3|UniProtKB=G3R0A6 G3R0A6 SYNDIG1L PTHR14768:SF4 UPF0338 PROTEIN SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1-LIKE membrane#GO:0016020;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000016912.3|UniProtKB=A0A2I2Z4P6 A0A2I2Z4P6 MAPRE3 PTHR10623:SF10 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 3 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 chromosome segregation#GO:0007059;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;intracellular protein localization#GO:0008104;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;cell cycle#GO:0007049;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;microtubule end#GO:1990752 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000009891.3|UniProtKB=G3RVJ1 G3RVJ1 FGF13 PTHR11486:SF77 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 13 fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;ion channel regulator activity#GO:0099106;protein binding#GO:0005515;molecular function activator activity#GO:0140677;channel regulator activity#GO:0016247;signaling receptor binding#GO:0005102;binding#GO:0005488;transporter regulator activity#GO:0141108 positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;positive regulation of cellular process#GO:0048522;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000016250.3|UniProtKB=G3S088 G3S088 ATP13A2 PTHR45630:SF2 CATION-TRANSPORTING ATPASE-RELATED POLYAMINE-TRANSPORTING ATPASE 13A2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;polyamine transmembrane transporter activity#GO:0015203 vacuole organization#GO:0007033;localization#GO:0051179;regulation of mitochondrion organization#GO:0010821;homeostatic process#GO:0042592;vesicle fusion#GO:0006906;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;membrane fusion#GO:0061025;nitrogen compound transport#GO:0071705;biological regulation#GO:0065007;membrane organization#GO:0061024;macroautophagy#GO:0016236;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;regulation of biological quality#GO:0065008;process utilizing autophagic mechanism#GO:0061919;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;regulation of cellular component organization#GO:0051128;chemical homeostasis#GO:0048878;regulation of anatomical structure size#GO:0090066;metabolic process#GO:0008152;intracellular calcium ion homeostasis#GO:0006874;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;monoatomic ion homeostasis#GO:0050801;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000016403.3|UniProtKB=A0A2I2ZEV0 A0A2I2ZEV0 RPP21 PTHR24103:SF639 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM39 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 protein stabilization#GO:0050821;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;defense response to other organism#GO:0098542;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;regulation of protein stability#GO:0031647;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;immune system process#GO:0002376;negative regulation of metabolic process#GO:0009892;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;negative regulation of macromolecule metabolic process#GO:0010605;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of proteasomal protein catabolic process#GO:1901799;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of signal transduction#GO:0009967 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000036502.1|UniProtKB=A0A2I2ZC09 A0A2I2ZC09 PTHR10653:SF2 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;regulation of actin filament organization#GO:0110053;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of actin filament depolymerization#GO:0030834;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493 cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000038502.1|UniProtKB=G3QHM8 G3QHM8 PRR23A PTHR31813:SF4 PROLINE-RICH PROTEIN 23B PROLINE-RICH PROTEIN 23A GORGO|Ensembl=ENSGGOG00000028525.2|UniProtKB=G3SHS9 G3SHS9 POTEA PTHR24147:SF68 ANKYRIN REPEAT DOMAIN 36-RELATED POTE ANKYRIN DOMAIN FAMILY MEMBER A GORGO|Ensembl=ENSGGOG00000016052.3|UniProtKB=G3RIZ6 G3RIZ6 SETD1A PTHR45814:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1A N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000043102.1|UniProtKB=A0A2I2ZKR4 A0A2I2ZKR4 SNRPE PTHR11193:SF9 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;U2 snRNP#GO:0005686;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000010452.3|UniProtKB=G3R4J3 G3R4J3 PTHR10075:SF123 BASIGIN RELATED IMMUNOGLOBULIN SUPERFAMILY DCC SUBCLASS MEMBER 3 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000012966.3|UniProtKB=G3RB16 G3RB16 SLC38A4 PTHR22950:SF222 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 4 L-amino acid transmembrane transporter activity#GO:0015179;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171 nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 amino acid transporter#PC00046;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000007884.3|UniProtKB=G3QXZ6 G3QXZ6 CDK13 PTHR24056:SF459 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 13 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;transferase complex#GO:1990234 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000025897.2|UniProtKB=G3S135 G3S135 LOC101144990 PTHR24031:SF625 RNA HELICASE RNA HELICASE protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003823.3|UniProtKB=G3QML3 G3QML3 IKZF5 PTHR24404:SF55 ZINC FINGER PROTEIN ZINC FINGER PROTEIN PEGASUS cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014749.3|UniProtKB=G3RFM0 G3RFM0 MPI PTHR10309:SF0 MANNOSE-6-PHOSPHATE ISOMERASE MANNOSE-6-PHOSPHATE ISOMERASE catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Mannose metabolism#P02752>Mannose 6-P isomerase#P03017 GORGO|Ensembl=ENSGGOG00000024093.2|UniProtKB=G3S415 G3S415 MAPRE2 PTHR10623:SF7 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 2 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cell cycle#GO:0007049;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;membraneless organelle assembly#GO:0140694;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;spindle assembly#GO:0051225;cellular process#GO:0009987;protein localization to microtubule cytoskeleton#GO:0072698;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;microtubule end#GO:1990752;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000027009.2|UniProtKB=G3S296 G3S296 PTHR21191:SF8 AQUAPORIN AQUAPORIN-12A-RELATED water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 biological regulation#GO:0065007;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;cellular component organization or biogenesis#GO:0071840;regulation of cell size#GO:0008361;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;regulation of anatomical structure size#GO:0090066;chemical homeostasis#GO:0048878 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000040306.1|UniProtKB=A0A2I2YH28 A0A2I2YH28 PTHR23037:SF49 CYTOKINE RECEPTOR SUBFAMILY NOT NAMED growth factor binding#GO:0019838;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;adaptive immune response#GO:0002250;interleukin-9-mediated signaling pathway#GO:0038113;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune system process#GO:0002376;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;cell communication#GO:0007154 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009178.3|UniProtKB=G3R1B2 G3R1B2 PUS1 PTHR11142:SF4 PSEUDOURIDYLATE SYNTHASE PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866;catalytic activity, acting on a tRNA#GO:0140101;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;pseudouridine synthesis#GO:0001522;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 lyase#PC00144 GORGO|Ensembl=ENSGGOG00000026297.2|UniProtKB=G3S2E7 G3S2E7 PTHR22747:SF28 NUCLEOPLASMIN NUCLEOPHOSMIN nucleic acid binding#GO:0003676;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515;RNA binding#GO:0003723 cellular component organization#GO:0016043;ribosomal large subunit export from nucleus#GO:0000055;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;regulation of cell cycle#GO:0051726;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular localization#GO:0051641;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cell cycle process#GO:0010564;positive regulation of transcription by RNA polymerase II#GO:0045944;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;organelle localization#GO:0051640;regulation of microtubule-based process#GO:0032886;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;nuclear transport#GO:0051169;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;regulation of gene expression#GO:0010468 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000044020.1|UniProtKB=A0A2I2YR32 A0A2I2YR32 PTHR24100:SF160 BUTYROPHILIN SELECTION AND UPKEEP OF INTRAEPITHELIAL T-CELLS PROTEIN 5-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000008702.3|UniProtKB=G3R033 G3R033 USP44 PTHR24006:SF895 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000008134.3|UniProtKB=G3QYK9 G3QYK9 MLN PTHR14156:SF0 MOTILIN PROMOTILIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 GORGO|Ensembl=ENSGGOG00000024442.2|UniProtKB=G3S986 G3S986 PTHR45616:SF26 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 8 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;actomyosin structure organization#GO:0031032;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000043431.1|UniProtKB=A0A2I2YXL8 A0A2I2YXL8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000013595.3|UniProtKB=G3RCN7 G3RCN7 FCRL3 PTHR11481:SF93 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 3 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;immune response#GO:0006955;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000009104.3|UniProtKB=A0A2I2Z4U1 A0A2I2Z4U1 COBLL1 PTHR21557:SF2 CORDON-BLEU CORDON-BLEU PROTEIN-LIKE 1 GORGO|Ensembl=ENSGGOG00000011053.3|UniProtKB=G3R639 G3R639 CRYL1 PTHR48075:SF1 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN LAMBDA-CRYSTALLIN HOMOLOG oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005466.3|UniProtKB=G3QRT9 G3QRT9 KANK1 PTHR24168:SF19 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein polymerization#GO:0032272;regulation of actin filament length#GO:0030832;negative regulation of cytoskeleton organization#GO:0051494;regulation of biological quality#GO:0065008;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of organelle organization#GO:0010639;cellular component organization#GO:0016043;negative regulation of cellular component organization#GO:0051129;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000002284.3|UniProtKB=G3QIN4 G3QIN4 TRAF1 PTHR10131:SF96 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 1 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;tumor necrosis factor receptor superfamily binding#GO:0032813;molecular adaptor activity#GO:0060090 cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;cytokine-mediated signaling pathway#GO:0019221;regulation of intracellular signal transduction#GO:1902531;response to peptide#GO:1901652;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;signal transduction#GO:0007165;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;response to tumor necrosis factor#GO:0034612;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040382.1|UniProtKB=A0A2I2YS22 A0A2I2YS22 PTHR24031:SF682 RNA HELICASE ATP-DEPENDENT RNA HELICASE ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396 organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010180.3|UniProtKB=G3RUC6 G3RUC6 AEN PTHR12801:SF57 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED APOPTOSIS-ENHANCING NUCLEASE nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640 gene expression#GO:0010467;RNA processing#GO:0006396;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;signaling#GO:0023052;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;intrinsic apoptotic signaling pathway#GO:0097193;RNA metabolic process#GO:0016070;signal transduction by p53 class mediator#GO:0072331;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000017094.3|UniProtKB=A0A2I2Y4L9 A0A2I2Y4L9 PRDM11 PTHR46880:SF11 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN PR_SET DOMAIN 11 GORGO|Ensembl=ENSGGOG00000041406.1|UniProtKB=A0A2I2Z186 A0A2I2Z186 PTHR15217:SF3 WILMS' TUMOR 1-ASSOCIATING PROTEIN PRE-MRNA-SPLICING REGULATOR WTAP enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000039303.1|UniProtKB=A0A2I2YNG1 A0A2I2YNG1 PTHR10715:SF7 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008227.3|UniProtKB=G3RMP3 G3RMP3 SERINC2 PTHR10383:SF22 SERINE INCORPORATOR SERINE INCORPORATOR 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000025481.2|UniProtKB=G3SEY6 G3SEY6 SCIMP PTHR12044:SF11 BCL2 INTERACTING MEDIATOR OF CELL DEATH SLP ADAPTER AND CSK-INTERACTING MEMBRANE PROTEIN positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of response to biotic stimulus#GO:0002833;meiotic nuclear division#GO:0140013;positive regulation of signal transduction#GO:0009967;cell cycle#GO:0007049;reproductive process#GO:0022414;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of response to external stimulus#GO:0032101;meiotic cell cycle#GO:0051321;cellular component organization or biogenesis#GO:0071840;positive regulation of response to external stimulus#GO:0032103;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;regulation of signaling#GO:0023051;nuclear division#GO:0000280;positive regulation of signaling#GO:0023056 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000005831.3|UniProtKB=G3RWG4 G3RWG4 PTHR12092:SF1 PLECKSTRIN PLECKSTRIN actin filament-based process#GO:0030029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000001917.3|UniProtKB=G3QHQ3 G3QHQ3 PKLR PTHR11817:SF31 PYRUVATE KINASE PYRUVATE KINASE PKLR transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;pyruvate kinase activity#GO:0004743;phosphotransferase activity, alcohol group as acceptor#GO:0016773 carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;cellular response to chemical stimulus#GO:0070887;pyruvate metabolic process#GO:0006090;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ADP metabolic process#GO:0046031;cellular response to insulin stimulus#GO:0032869;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;response to peptide hormone#GO:0043434;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;pyridine nucleotide catabolic process#GO:0019364;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;response to endogenous stimulus#GO:0009719;purine-containing compound catabolic process#GO:0072523;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;response to chemical#GO:0042221;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;response to hormone#GO:0009725;response to nitrogen compound#GO:1901698;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate metabolic process#GO:0006753;cellular response to peptide hormone stimulus#GO:0071375;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;cellular response to nitrogen compound#GO:1901699;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132;Glycolysis#P00024>Pyruvate kinase#P00675 GORGO|Ensembl=ENSGGOG00000000043.3|UniProtKB=G3QCU4 G3QCU4 SYTL1 PTHR45716:SF3 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 secretion by cell#GO:0032940;exocytosis#GO:0006887;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000025831.2|UniProtKB=A0A2I2Y5K3 A0A2I2Y5K3 LOC101136143 PTHR48188:SF2 60S RIBOSOMAL PROTEIN L43 LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000022489.2|UniProtKB=G3S755 G3S755 TUBAL3 PTHR11588:SF278 TUBULIN TUBULIN ALPHA CHAIN-LIKE 3 anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010 supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;tubulin#PC00228 GORGO|Ensembl=ENSGGOG00000004308.3|UniProtKB=G3QNV0 G3QNV0 HIF1AN PTHR12461:SF108 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of Notch signaling pathway#GO:0045746;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000024803.2|UniProtKB=G3S7D0 G3S7D0 PTHR23266:SF384 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-53-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000016225.3|UniProtKB=A0A2I2Z0X2 A0A2I2Z0X2 RIOX2 PTHR13096:SF7 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 2 GORGO|Ensembl=ENSGGOG00000010880.3|UniProtKB=G3R5M5 G3R5M5 VDAC1 PTHR11743:SF13 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL NON-SELECTIVE VOLTAGE-GATED ION CHANNEL VDAC1 passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;channel activity#GO:0015267 localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;intracellular transport#GO:0046907;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;cell periphery#GO:0071944;organelle outer membrane#GO:0031968;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000041282.1|UniProtKB=A0A2I2YSI4 A0A2I2YSI4 PTHR12735:SF41 BOLA-LIKE PROTEIN-RELATED BOLA FAMILY MEMBER 2 iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000006149.3|UniProtKB=A0A2I2YH19 A0A2I2YH19 EHF PTHR11849:SF171 ETS ETS HOMOLOGOUS FACTOR transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000006214.3|UniProtKB=A0A2I2YEL4 A0A2I2YEL4 IRF6 PTHR11949:SF9 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000005609.3|UniProtKB=G3QS71 G3QS71 XPO6 PTHR21452:SF4 EXPORTIN-6 EXPORTIN-6 protein export from nucleus#GO:0006611;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913 GORGO|Ensembl=ENSGGOG00000010746.3|UniProtKB=G3R5A9 G3R5A9 TALDO1 PTHR10683:SF44 TRANSALDOLASE TRANSALDOLASE transaldolase activity#GO:0004801;transketolase or transaldolase activity#GO:0016744;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;aldolase#PC00044;lyase#PC00144 Pentose phosphate pathway#P02762>Transaldolase#P03081 GORGO|Ensembl=ENSGGOG00000008689.3|UniProtKB=G3R019 G3R019 TMEM174 PTHR31020:SF1 TRANSMEMBRANE PROTEIN 174 TRANSMEMBRANE PROTEIN 174 GORGO|Ensembl=ENSGGOG00000011615.3|UniProtKB=G3R7K0 G3R7K0 SEC31A PTHR13923:SF23 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31A cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 intracellular organelle#GO:0043229;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle coat#GO:0030120;cytoplasm#GO:0005737 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000034898.2|UniProtKB=G3SKJ0 G3SKJ0 SNX27 PTHR12431:SF19 SORTING NEXIN 17 AND 27 SORTING NEXIN-27 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule metabolic process#GO:0043170;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005066.3|UniProtKB=A0A2I2ZEG1 A0A2I2ZEG1 HPN PTHR24253:SF166 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE HEPSIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002122.3|UniProtKB=G3QI85 G3QI85 MIXL1 PTHR47656:SF1 HOMEOBOX PROTEIN MIXL HOMEOBOX PROTEIN MIXL1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000015185.3|UniProtKB=G3RGQ9 G3RGQ9 TJAP1 PTHR28664:SF3 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000003905.3|UniProtKB=G3QMT7 G3QMT7 MPHOSPH10 PTHR17039:SF0 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000027893.2|UniProtKB=G3RX67 G3RX67 INAFM1 PTHR34929:SF2 ZGC:153157 TRANSMEMBRANE PROTEIN INAFM1-RELATED GORGO|Ensembl=ENSGGOG00000009173.3|UniProtKB=G3R1B1 G3R1B1 GTF2H3 PTHR12831:SF0 TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 GORGO|Ensembl=ENSGGOG00000011346.3|UniProtKB=G3SCF3 G3SCF3 ACTR3 PTHR11937:SF175 ACTIN ACTIN-RELATED PROTEIN 3 actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;structural molecule activity#GO:0005198 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000042350.1|UniProtKB=A0A2I2YAH8 A0A2I2YAH8 PPP1R9B PTHR16154:SF24 NEURABIN NEURABIN-2 protein-containing complex binding#GO:0044877;protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090 supramolecular fiber organization#GO:0097435;system development#GO:0048731;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;actin filament organization#GO:0007015;neurogenesis#GO:0022008;calcium-mediated signaling#GO:0019722;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996 cell periphery#GO:0071944;neuron projection#GO:0043005;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cortical cytoskeleton#GO:0030863;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dendrite#GO:0030425;filopodium#GO:0030175;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000040771.1|UniProtKB=G3QWS8 G3QWS8 KIAA0408 PTHR15705:SF1 MCG7194, ISOFORM CRA_A RIKEN CDNA 9330159F19 GENE GORGO|Ensembl=ENSGGOG00000016801.3|UniProtKB=A0A2I2Z7W3 A0A2I2Z7W3 PTHR43270:SF1 BETA-ALA-HIS DIPEPTIDASE BETA-ALA-HIS DIPEPTIDASE catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000038650.1|UniProtKB=A0A2I2Y9G9 A0A2I2Y9G9 PTHR11581:SF23 30S/40S RIBOSOMAL PROTEIN S4 RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009795.3|UniProtKB=G3R2V4 G3R2V4 ENPP7 PTHR10151:SF63 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 7 phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;sphingomyelin metabolic process#GO:0006684;phospholipid metabolic process#GO:0006644;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 actin-based cell projection#GO:0098858;microvillus#GO:0005902;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000042881.1|UniProtKB=A0A2I2Z9A9 A0A2I2Z9A9 PTHR23281:SF41 MERLIN/MOESIN/EZRIN/RADIXIN FERM DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;filopodium#GO:0030175;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000037361.1|UniProtKB=G3SHH9 G3SHH9 LOC101126757 PTHR26453:SF613 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10H4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000017112.4|UniProtKB=G3RLP4 G3RLP4 CORO1C PTHR10856:SF10 CORONIN CORONIN-1C protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488 cytoskeleton organization#GO:0007010;neural crest cell development#GO:0014032;tissue development#GO:0009888;cell migration#GO:0016477;cellular process#GO:0009987;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;organelle organization#GO:0006996;mesenchyme development#GO:0060485;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;mesenchymal cell differentiation#GO:0048762;neural crest cell differentiation#GO:0014033;developmental process#GO:0032502;cell development#GO:0048468;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;cell differentiation#GO:0030154;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;stem cell development#GO:0048864 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;lamellipodium#GO:0030027;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;actin filament#GO:0005884 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000022495.2|UniProtKB=G3RZT0 G3RZT0 GTF2E2 PTHR12716:SF8 TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488;transcription factor binding#GO:0008134;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transferase complex#GO:1990234;protein-containing complex#GO:0032991;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;General transcription regulation#P00023>TFIIEbeta#P00659;Transcription regulation by bZIP transcription factor#P00055>TFIIEbeta#P01386;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395 GORGO|Ensembl=ENSGGOG00000010717.3|UniProtKB=G3R580 G3R580 EXOC3L2 PTHR21292:SF7 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810 cytoplasm#GO:0005737;exocyst#GO:0000145;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell cortex#GO:0005938;cell periphery#GO:0071944;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000034827.2|UniProtKB=A0A2I2YBF3 A0A2I2YBF3 MAMDC4 PTHR23282:SF129 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. APICAL ENDOSOMAL GLYCOPROTEIN GORGO|Ensembl=ENSGGOG00000010796.3|UniProtKB=G3R5F5 G3R5F5 CDKL5 PTHR24056:SF111 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 5 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000014723.3|UniProtKB=G3RFJ3 G3RFJ3 SOCS1 PTHR10155:SF4 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 cytokine-mediated signaling pathway#GO:0019221;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;response to peptide#GO:1901652;negative regulation of biological process#GO:0048519;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;signal transduction#GO:0007165;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968 kinase modulator#PC00140 JAK/STAT signaling pathway#P00038>SOCS#P01030 GORGO|Ensembl=ENSGGOG00000041142.1|UniProtKB=A0A2I2ZTK2 A0A2I2ZTK2 PTHR10666:SF359 UBIQUITIN UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;nucleus#GO:0005634;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000008863.3|UniProtKB=G3S8Z3 G3S8Z3 ASPH PTHR12366:SF33 ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE ASPARTYL_ASPARAGINYL BETA-HYDROXYLASE catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cytosolic calcium ion concentration#GO:0051480;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009690.3|UniProtKB=G3QTK9 G3QTK9 UNC119 PTHR12951:SF5 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG A lipid binding#GO:0008289;binding#GO:0005488 localization#GO:0051179;organelle assembly#GO:0070925;mitotic cytokinesis#GO:0000281;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;negative regulation of transport#GO:0051051;negative regulation of cellular component organization#GO:0051129;cell cycle#GO:0007049;cell division#GO:0051301;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;intracellular protein localization#GO:0008104;negative regulation of cellular process#GO:0048523;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;protein transport#GO:0015031;cilium organization#GO:0044782;cytokinesis#GO:0000910;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of receptor-mediated endocytosis#GO:0048259;cellular component organization#GO:0016043;cilium assembly#GO:0060271;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cell projection assembly#GO:0030031 cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;membrane-bounded organelle#GO:0043227;spindle pole#GO:0000922;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012803.3|UniProtKB=G3RAL3 G3RAL3 PPP1R17 PTHR15387:SF0 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 17 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 17 phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein serine/threonine phosphatase inhibitor activity#GO:0004865 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000010835.3|UniProtKB=G3R5J4 G3R5J4 LOC101139167 PTHR22762:SF60 ALPHA-GLUCOSIDASE NEUTRAL ALPHA-GLUCOSIDASE C catalytic activity#GO:0003824;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;alpha-glucosidase activity#GO:0090599;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487 glucosidase#PC00108 GORGO|Ensembl=ENSGGOG00000039306.1|UniProtKB=A0A2I2YE40 A0A2I2YE40 TNFRSF11B PTHR23097:SF90 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11B transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000189.3|UniProtKB=G3QD76 G3QD76 CILK1 PTHR24055:SF260 MITOGEN-ACTIVATED PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE ICK protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular response to stimulus#GO:0051716;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;signaling#GO:0023052;response to stimulus#GO:0050896;cell projection organization#GO:0030030;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000005989.3|UniProtKB=G3QT53 G3QT53 DDX39B PTHR47958:SF124 ATP-DEPENDENT RNA HELICASE DBP3 SPLICEOSOME RNA HELICASE DDX39B helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;localization#GO:0051179;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;RNA splicing, via transesterification reactions#GO:0000375;nucleocytoplasmic transport#GO:0006913;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;mRNA export from nucleus#GO:0006406;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;nucleic acid biosynthetic process#GO:0141187 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000010102.3|UniProtKB=G3R3M4 G3R3M4 KDM4D PTHR10694:SF21 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4D demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000001863.3|UniProtKB=A0A2I2Y7S3 A0A2I2Y7S3 IST1 PTHR12161:SF56 IST1 FAMILY MEMBER IST1 HOMOLOG macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179 GORGO|Ensembl=ENSGGOG00000000450.3|UniProtKB=G3S5F3 G3S5F3 DOP1A PTHR14042:SF22 DOPEY-RELATED PROTEIN DOP1A intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;retrograde transport, vesicle recycling within Golgi#GO:0000301;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000000353.3|UniProtKB=G3SC82 G3SC82 PTHR45615:SF8 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIB catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000011386.3|UniProtKB=G3S6X0 G3S6X0 ELOVL5 PTHR11157:SF18 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 5 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000043313.1|UniProtKB=A0A2I2ZJZ0 A0A2I2ZJZ0 PTHR13693:SF105 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000014057.3|UniProtKB=G3RDX0 G3RDX0 PI4K2B PTHR12865:SF6 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-BETA kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;Golgi organization#GO:0007030;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;endomembrane system organization#GO:0010256;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;organelle organization#GO:0006996;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosome organization#GO:0007032;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629 Golgi apparatus#GO:0005794;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009044.3|UniProtKB=G3R0Z5 G3R0Z5 LOC101138570 PTHR12151:SF4 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER CYTOCHROME C OXIDASE ASSEMBLY FACTOR SCO1 cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 oxidoreductase#PC00176;oxidase#PC00175;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000001015.3|UniProtKB=G3QFD1 G3QFD1 FAM124B PTHR14715:SF2 FAM124 DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN FAM124B intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 GORGO|Ensembl=ENSGGOG00000027353.2|UniProtKB=A0A2I2YJ72 A0A2I2YJ72 POU3F4 PTHR11636:SF83 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000016720.3|UniProtKB=A0A2I2ZNW4 A0A2I2ZNW4 BAZ2B PTHR45915:SF1 TRANSCRIPTION INTERMEDIARY FACTOR BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000015827.3|UniProtKB=G3RIE1 G3RIE1 GRN PTHR12274:SF9 GRANULIN PROGRANULIN regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of biological process#GO:0050789;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000028335.2|UniProtKB=G3RS30 G3RS30 RBP7 PTHR11955:SF97 FATTY ACID BINDING PROTEIN RETINOID-BINDING PROTEIN 7 lipid binding#GO:0008289;fatty acid binding#GO:0005504;organic acid binding#GO:0043177;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;lipid transport#GO:0006869;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000015096.3|UniProtKB=G3RNJ2 G3RNJ2 NUP210 PTHR23019:SF2 NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210 nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011148.3|UniProtKB=G3R6C2 G3R6C2 SPRY2 PTHR12365:SF8 SPROUTY PROTEIN SPROUTY HOMOLOG 2 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860 regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of Ras protein signal transduction#GO:0046578;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>SPRY#G01511;EGF receptor signaling pathway#P00018>Spry#P00541;FGF signaling pathway#P00021>Spry#P00626 GORGO|Ensembl=ENSGGOG00000015907.3|UniProtKB=G3RIL1 G3RIL1 TBC1D26 PTHR22957:SF598 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 26 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000013590.3|UniProtKB=G3RCM7 G3RCM7 BOP1 PTHR17605:SF0 RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN RIBOSOME BIOGENESIS PROTEIN BOP1 RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011859.3|UniProtKB=G3R866 G3R866 MSL1 PTHR21656:SF2 MALE-SPECIFIC LETHAL-1 PROTEIN MALE-SPECIFIC LETHAL 1 HOMOLOG binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin binding#GO:0003682 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromatin#GO:0000785;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000026065.2|UniProtKB=G3RZM1 G3RZM1 BORCS5 PTHR31634:SF2 BLOC-1-RELATED COMPLEX SUBUNIT 5 BLOC-1-RELATED COMPLEX SUBUNIT 5 intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049;microtubule-based process#GO:0007017;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;establishment of localization in cell#GO:0051649;lysosome localization#GO:0032418;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;organelle transport along microtubule#GO:0072384;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;regulation of biological process#GO:0050789;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;side of membrane#GO:0098552;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;lytic vacuole#GO:0000323;presynapse#GO:0098793;lysosomal membrane#GO:0005765;secretory vesicle#GO:0099503;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658 GORGO|Ensembl=ENSGGOG00000004752.3|UniProtKB=G3QPZ5 G3QPZ5 TRAPPC3 PTHR13048:SF2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 establishment of localization in cell#GO:0051649;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 vesicle tethering complex#GO:0099023;cis-Golgi network#GO:0005801;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytosol#GO:0005829;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000022845.2|UniProtKB=G3RZB7 G3RZB7 TAS2R39 PTHR11394:SF142 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 39 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037037.1|UniProtKB=A0A2I2ZMV7 A0A2I2ZMV7 GEMIN7 PTHR14679:SF1 GEM-ASSOCIATED PROTEIN 7 GEM-ASSOCIATED PROTEIN 7 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618 Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000007057.3|UniProtKB=G3QVW6 G3QVW6 RSBN1L PTHR13354:SF9 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE RSBN1L histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000015035.3|UniProtKB=A0A2I2YR64 A0A2I2YR64 IGF2BP2 PTHR10288:SF93 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;negative regulation of catabolic process#GO:0009895;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000026077.2|UniProtKB=G3S5N1 G3S5N1 METTL21C PTHR14614:SF13 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE METHYLTRANSFERASE METTL21C protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010061.3|UniProtKB=G3S8X1 G3S8X1 PTHR15666:SF2 COMM DOMAIN CONTAINING PROTEIN 5 COMM DOMAIN-CONTAINING PROTEIN 5 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000014264.3|UniProtKB=G3RUG2 G3RUG2 PTHR48188:SF6 60S RIBOSOMAL PROTEIN L43 RIBOSOMAL PROTEIN EL43-LIKE-RELATED ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006380.3|UniProtKB=G3QU50 G3QU50 SGO1 PTHR21577:SF4 SHUGOSHIN SHUGOSHIN 1 meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic chromosome segregation#GO:0045132;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;microtubule organizing center organization#GO:0031023;meiotic sister chromatid cohesion#GO:0051177;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;mitotic sister chromatid cohesion#GO:0007064;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;sister chromatid cohesion#GO:0007062;organelle fission#GO:0048285;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;reproductive process#GO:0022414;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098 condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 centromere DNA-binding protein#PC00071 GORGO|Ensembl=ENSGGOG00000010132.3|UniProtKB=G3R3Q6 G3R3Q6 KLHL10 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011758.3|UniProtKB=A0A2I2ZG10 A0A2I2ZG10 NMNAT2 PTHR12039:SF18 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 nucleotidyltransferase#PC00174;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000037553.1|UniProtKB=A0A2I2YW98 A0A2I2YW98 PTHR16821:SF5 FRATAXIN FRATAXIN iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;molecular carrier activity#GO:0140104;binding#GO:0005488;small molecule binding#GO:0036094;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198 iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000003693.3|UniProtKB=G3QM95 G3QM95 SNAPC5 PTHR15333:SF2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 GORGO|Ensembl=ENSGGOG00000003498.3|UniProtKB=A0A2I2YR12 A0A2I2YR12 HNRNPM PTHR23003:SF6 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN M binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000000535.3|UniProtKB=A0A2I2Z3G6 A0A2I2Z3G6 PTHR43625:SF52 AFLATOXIN B1 ALDEHYDE REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cellular process#GO:0009987;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to toxic substance#GO:0009636;detoxification#GO:0098754;metabolic process#GO:0008152;secondary metabolic process#GO:0019748 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000007649.3|UniProtKB=G3QXD9 G3QXD9 ZAR1 PTHR31054:SF6 ZYGOTE ARREST PROTEIN 1-LIKE ISOFORM X1 ZYGOTE ARREST PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;negative regulation of protein metabolic process#GO:0051248;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cell maturation#GO:0048469;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;developmental maturation#GO:0021700;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of translation#GO:0017148;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;oogenesis#GO:0048477;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000003240.3|UniProtKB=G3QL52 G3QL52 IPO11 PTHR10997:SF7 IMPORTIN-7, 8, 11 IMPORTIN-11 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nucleocytoplasmic transport#GO:0006913;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000041052.1|UniProtKB=A0A2I2YUQ3 A0A2I2YUQ3 PTHR15825:SF3 UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-FOLD MODIFIER 1 process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;macroautophagy#GO:0016236;response to stimulus#GO:0050896;catabolic process#GO:0009056;autophagy#GO:0006914;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;reticulophagy#GO:0061709;response to stress#GO:0006950 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000022009.2|UniProtKB=G3SBZ1 G3SBZ1 BEX1 PTHR19430:SF3 PROTEIN BEX1-RELATED PROTEIN BEX1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000001048.3|UniProtKB=G3QFG0 G3QFG0 IL3 PTHR48489:SF1 INTERLEUKIN-3 INTERLEUKIN-3 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Interleukin signaling pathway#P00036>Interleukin#P00970 GORGO|Ensembl=ENSGGOG00000000922.3|UniProtKB=G3SJX7 G3SJX7 TGFBR3 PTHR14002:SF7 ENDOGLIN/TGF-BETA RECEPTOR TYPE III TRANSFORMING GROWTH FACTOR BETA RECEPTOR TYPE 3 signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539;molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;transforming growth factor beta binding#GO:0050431;catalytic activity#GO:0003824;cytokine binding#GO:0019955;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine receptor binding#GO:0005126;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;growth factor binding#GO:0019838;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;transferase activity#GO:0016740;carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023 response to transforming growth factor beta#GO:0071559;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;mesenchyme development#GO:0060485;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;mesenchymal cell differentiation#GO:0048762;cell surface receptor signaling pathway#GO:0007166;animal organ development#GO:0048513;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>TBRIII#P06806 GORGO|Ensembl=ENSGGOG00000009780.3|UniProtKB=G3R2U1 G3R2U1 PTHR24393:SF168 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 470 sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010087.3|UniProtKB=G3S1P5 G3S1P5 CYTH1 PTHR10663:SF340 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000009113.3|UniProtKB=G3RDM8 G3RDM8 UNC13A PTHR10480:SF1 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG A binding#GO:0005488;calmodulin binding#GO:0005516;SNARE binding#GO:0000149;syntaxin binding#GO:0019905;protein binding#GO:0005515 synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656;secretion by cell#GO:0032940;cellular localization#GO:0051641;vesicle localization#GO:0051648;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;calcium-ion regulated exocytosis#GO:0017156;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903 synaptic membrane#GO:0097060;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular vesicle#GO:0097708;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;axon terminus#GO:0043679;organelle membrane#GO:0031090;neuromuscular junction#GO:0031594;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;distal axon#GO:0150034;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306 GORGO|Ensembl=ENSGGOG00000007863.3|UniProtKB=G3QXX2 G3QXX2 RNGTT PTHR10367:SF17 MRNA-CAPPING ENZYME MRNA-CAPPING ENZYME catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 RNA processing factor#PC00147;mRNA capping factor#PC00145 GORGO|Ensembl=ENSGGOG00000006463.3|UniProtKB=G3QUB9 G3QUB9 ZNF212 PTHR24390:SF49 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 212 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000000246.3|UniProtKB=G3RXU9 G3RXU9 BTBD10 PTHR21637:SF5 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN 10 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016391.3|UniProtKB=G3RJV3 G3RJV3 FCHSD1 PTHR15735:SF4 FCH AND DOUBLE SH3 DOMAINS PROTEIN F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 1 ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament-based process#GO:0032970;neuromuscular synaptic transmission#GO:0007274;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;chemical synaptic transmission#GO:0007268;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;regulation of actin filament length#GO:0030832;cell communication#GO:0007154;regulation of biological quality#GO:0065008 neuromuscular junction#GO:0031594;cell junction#GO:0030054;recycling endosome#GO:0055037;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000004068.3|UniProtKB=A0A2I2YKC9 A0A2I2YKC9 ZNF26 PTHR24381:SF455 ZINC FINGER PROTEIN RB-ASSOCIATED KRAB ZINC FINGER PROTEIN-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008648.3|UniProtKB=A0A2I2YL70 A0A2I2YL70 PRPF19 PTHR43995:SF1 PRE-MRNA-PROCESSING FACTOR 19 PRE-MRNA-PROCESSING FACTOR 19 ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA processing factor#PC00147;RNA metabolism protein#PC00031 mRNA splicing#P00058>U4#P01476 GORGO|Ensembl=ENSGGOG00000011481.3|UniProtKB=G3RM93 G3RM93 SMURF1 PTHR11254:SF293 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF1 acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;primary metabolic process#GO:0044238;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of BMP signaling pathway#GO:0030514;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490;TGF-beta signaling pathway#P00052>Smurfs#P01279 GORGO|Ensembl=ENSGGOG00000006143.3|UniProtKB=G3QTJ1 G3QTJ1 PUM3 PTHR13389:SF0 PUMILIO HOMOLOG 3 PUMILIO HOMOLOG 3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of biological process#GO:0050789;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000009339.3|UniProtKB=G3R1P3 G3R1P3 ARL16 PTHR46688:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 GORGO|Ensembl=ENSGGOG00000034883.2|UniProtKB=G3SKK1 G3SKK1 GSAP PTHR13630:SF1 GAMMA-SECRETASE-ACTIVATING PROTEIN GAMMA-SECRETASE-ACTIVATING PROTEIN regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000016630.3|UniProtKB=G3RKF9 G3RKF9 CCDC8 PTHR47741:SF1 COILED COIL DOMAIN-CONTAINING PROTEIN 8, CCDC8 COILED-COIL DOMAIN-CONTAINING PROTEIN 8 cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;microtubule cytoskeleton organization#GO:0000226;organelle organization#GO:0006996;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of nuclear division#GO:0051783;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of mitotic nuclear division#GO:0007088 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000001144.3|UniProtKB=G3S4J2 G3S4J2 TRIM23 PTHR11711:SF163 ADP RIBOSYLATION FACTOR-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM23 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000036359.1|UniProtKB=A0A2I2YFZ3 A0A2I2YFZ3 PTHR23267:SF484 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 38-2_DELTA VARIABLE 8 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000042206.1|UniProtKB=A0A2I2Z285 A0A2I2Z285 LOC109024409 PTHR11502:SF34 40S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN ES6 ribosomal protein#PC00202 CCKR signaling map#P06959>RPS6#P07143 GORGO|Ensembl=ENSGGOG00000012563.3|UniProtKB=G3RA05 G3RA05 CACFD1 PTHR13314:SF2 CALCIUM CHANNEL FLOWER HOMOLOG CALCIUM CHANNEL FLOWER HOMOLOG calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;calcium ion transport#GO:0006816;synaptic vesicle endocytosis#GO:0048488;calcium ion transmembrane transport#GO:0070588;endocytosis#GO:0006897;metal ion transport#GO:0030001;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506 GORGO|Ensembl=ENSGGOG00000003743.3|UniProtKB=G3QMD9 G3QMD9 PANX PTHR15759:SF3 PANNEXIN PANNEXIN-3 wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001642.3|UniProtKB=A0A2I2ZUP0 A0A2I2ZUP0 MVK PTHR43290:SF4 MEVALONATE KINASE MEVALONATE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;cholesterol biosynthetic process#GO:0006695;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;isoprenoid biosynthetic process#GO:0008299;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;acyl-CoA metabolic process#GO:0006637;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;nucleoside phosphate metabolic process#GO:0006753;phospholipid biosynthetic process#GO:0008654;acetyl-CoA metabolic process#GO:0006084;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 Cholesterol biosynthesis#P00014>Mevalonate kinase#P00492 GORGO|Ensembl=ENSGGOG00000016361.3|UniProtKB=G3RJR7 G3RJR7 SLC35E1 PTHR11132:SF427 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E1 antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023976.2|UniProtKB=G3SC88 G3SC88 PTHR23411:SF36 TAPASIN IMMUNOGLOBULIN KAPPA CONSTANT immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000024909.2|UniProtKB=G3RT40 G3RT40 PTHR11817:SF80 PYRUVATE KINASE PYRUVATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;pyruvate kinase activity#GO:0004743;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to insulin#GO:0032868;purine nucleoside triphosphate metabolic process#GO:0009144;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;response to peptide hormone#GO:0043434;cellular response to insulin stimulus#GO:0032869;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;cellular response to chemical stimulus#GO:0070887;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;cellular response to peptide hormone stimulus#GO:0071375;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;response to nitrogen compound#GO:1901698;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;cellular response to nitrogen compound#GO:1901699;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ribonucleoside diphosphate metabolic process#GO:0009185;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;response to endogenous stimulus#GO:0009719;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;response to hormone#GO:0009725;response to chemical#GO:0042221;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000040400.1|UniProtKB=G3RTV7 G3RTV7 LOC101140583 PTHR23203:SF15 PROLINE-RICH PROTEIN BASIC SALIVARY PROLINE-RICH PROTEIN 4 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000001360.3|UniProtKB=G3QG90 G3QG90 GARIN5B PTHR22574:SF12 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 5B GORGO|Ensembl=ENSGGOG00000015306.3|UniProtKB=G3SGW8 G3SGW8 ELOB PTHR13248:SF5 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2 ELONGIN-B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;post-transcriptional gene silencing#GO:0016441;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;proteasomal protein catabolic process#GO:0010498;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of gene silencing by regulatory ncRNA#GO:0060966;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 Cul3-RING ubiquitin ligase complex#GO:0031463;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cullin-RING ubiquitin ligase complex#GO:0031461;organelle lumen#GO:0043233 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000005634.3|UniProtKB=G3QS87 G3QS87 PSMA7 PTHR11599:SF40 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 proteasome complex#GO:0000502;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000014788.3|UniProtKB=G3SGU4 G3SGU4 SLC35F1 PTHR14233:SF10 DUF914-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F1 GORGO|Ensembl=ENSGGOG00000005061.3|UniProtKB=G3QQT6 G3QQT6 PITPNB PTHR10658:SF27 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN BETA ISOFORM binding#GO:0005488;molecular carrier activity#GO:0140104;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylcholine intramembrane carrier activity#GO:0008525;ion binding#GO:0043167;lipid carrier activity#GO:0005319;cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303;phospholipid binding#GO:0005543;phosphatidylinositol binding#GO:0035091;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine binding#GO:0031210 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012662.3|UniProtKB=A0A2I2ZK96 A0A2I2ZK96 TRAPPC2L PTHR12403:SF23 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-LIKE PROTEIN cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015247.3|UniProtKB=G3RGW4 G3RGW4 PI4K2A PTHR12865:SF7 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;Golgi organization#GO:0007030;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosome organization#GO:0007032;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;endomembrane system organization#GO:0010256 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000001928.3|UniProtKB=G3QHR6 G3QHR6 HSP90B1 PTHR11528:SF96 HEAT SHOCK PROTEIN 90 FAMILY MEMBER ENDOPLASMIN ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein folding#GO:0006457;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to chemical#GO:0042221;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 Hsp90 family chaperone#PC00028;chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000012055.3|UniProtKB=G3SFZ7 G3SFZ7 PTHR14735:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000041535.1|UniProtKB=A0A2I2YLG5 A0A2I2YLG5 AP1S3 PTHR11753:SF18 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-3 transport#GO:0006810;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000016479.3|UniProtKB=G3RK21 G3RK21 HMGN5 PTHR23145:SF6 NUCLEOSOMAL BINDING PROTEIN 1 HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 5 GORGO|Ensembl=ENSGGOG00000015042.3|UniProtKB=G3RGE6 G3RGE6 LIG1 PTHR45674:SF15 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on DNA#GO:0140097 DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cell cycle process#GO:0022402;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA strand elongation involved in DNA replication#GO:0006271;mitotic cell cycle#GO:0000278;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;DNA ligase#PC00012 GORGO|Ensembl=ENSGGOG00000027867.2|UniProtKB=G3RV88 G3RV88 PTHR14882:SF3 COILED-COIL DOMAIN-CONTAINING 74A COILED-COIL DOMAIN-CONTAINING 92B GORGO|Ensembl=ENSGGOG00000036119.1|UniProtKB=A0A2I2YUP6 A0A2I2YUP6 CHRM2 PTHR24247:SF207 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M2 transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536;regulation of multicellular organismal process#GO:0051239;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of system process#GO:0044057;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of smooth muscle contraction#GO:0006940;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of muscle system process#GO:0090257;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;trans-synaptic signaling#GO:0099537;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of muscle contraction#GO:0006937;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>mAChR2/4#P01077;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 GORGO|Ensembl=ENSGGOG00000007213.3|UniProtKB=G3RRM5 G3RRM5 RAB11FIP2 PTHR15746:SF20 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 2 export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;secretion by cell#GO:0032940;exocytosis#GO:0006887;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;transport#GO:0006810;regulated exocytosis#GO:0045055 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000011183.3|UniProtKB=G3R6F9 G3R6F9 CHIT1 PTHR11177:SF407 CHITINASE CHITOTRIOSIDASE-1 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000002194.3|UniProtKB=A0A2I2YG22 A0A2I2YG22 ARHGEF10L PTHR12877:SF16 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 10-LIKE PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;positive regulation of organelle organization#GO:0010638;cellular response to stress#GO:0033554;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;regulation of stress fiber assembly#GO:0051492;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;actin filament-based process#GO:0030029;SREBP signaling pathway#GO:0032933;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000000235.3|UniProtKB=A0A2I2ZQ27 A0A2I2ZQ27 SREK1IP1 PTHR31437:SF1 SREK1IP1 FAMILY MEMBER PROTEIN SREK1IP1 GORGO|Ensembl=ENSGGOG00000014638.3|UniProtKB=G3RFC3 G3RFC3 NCKAP5 PTHR21740:SF0 NCK-ASSOCIATED PROTEIN 5 NCK-ASSOCIATED PROTEIN 5 supramolecular fiber organization#GO:0097435;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular component disassembly#GO:0022411;microtubule bundle formation#GO:0001578;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component organization#GO:0016043 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;microtubule end#GO:1990752;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;microtubule plus-end#GO:0035371;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000008249.3|UniProtKB=G3QYX9 G3QYX9 HERC4 PTHR45622:SF5 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC4-RELATED ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005883.3|UniProtKB=G3QSW6 G3QSW6 ATAD5 PTHR23389:SF21 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5 nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000039582.1|UniProtKB=A0A2I2ZAN6 A0A2I2ZAN6 TMEM107 PTHR34341:SF1 TRANSMEMBRANE PROTEIN 107 TRANSMEMBRANE PROTEIN 107 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;localization#GO:0051179;organelle assembly#GO:0070925;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;cilium assembly#GO:0060271 membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000026820.2|UniProtKB=G3SI34 G3SI34 LOC101124358 PTHR36131:SF1 KERATIN-ASSOCIATED PROTEIN 8-1 KERATIN-ASSOCIATED PROTEIN 8-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000012815.3|UniProtKB=G3RAM3 G3RAM3 GPR50 PTHR24228:SF56 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN-RELATED RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000039750.1|UniProtKB=A0A2I2Y6Q9 A0A2I2Y6Q9 TMEM140 PTHR16103:SF0 TRANSMEMBRANE PROTEIN 140 TRANSMEMBRANE PROTEIN 140 GORGO|Ensembl=ENSGGOG00000003473.3|UniProtKB=G3QLQ2 G3QLQ2 NSL1 PTHR31749:SF3 KINETOCHORE-ASSOCIATED PROTEIN NSL1 HOMOLOG KINETOCHORE-ASSOCIATED PROTEIN NSL1 HOMOLOG intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;outer kinetochore#GO:0000940;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793 GORGO|Gene=CCHCR1|UniProtKB=Q8HZ59 Q8HZ59 CCHCR1 PTHR46822:SF1 COILED-COIL ALPHA-HELICAL ROD PROTEIN 1 COILED-COIL ALPHA-HELICAL ROD PROTEIN 1 protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;protein export from nucleus#GO:0006611;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000028385.2|UniProtKB=G3S0T7 G3S0T7 PTHR11489:SF17 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2-RELATED structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;translation#GO:0006412;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000040229.1|UniProtKB=A0A2I2YWA3 A0A2I2YWA3 MS4A18 PTHR23320:SF37 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 18 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015324.3|UniProtKB=A0A2I2ZWN9 A0A2I2ZWN9 ANKH PTHR28384:SF1 PROGRESSIVE ANKYLOSIS PROTEIN HOMOLOG MINERALIZATION REGULATOR ANKH active transmembrane transporter activity#GO:0022804;phosphate transmembrane transporter activity#GO:0005315;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000034863.2|UniProtKB=G3SKQ9 G3SKQ9 SUGCT PTHR48207:SF3 SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE SUCCINYL-COA:GLUTARATE COA-TRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 Carnitine metabolism#P02733>Carnitine dehydratase#P02866;Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864 GORGO|Ensembl=ENSGGOG00000009069.3|UniProtKB=G3RNK0 G3RNK0 GINS2 PTHR12772:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950;cellular process#GO:0009987;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA replication preinitiation complex#GO:0031261;chromosome#GO:0005694;organelle lumen#GO:0043233;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 GORGO|Gene=MT-ND4|UniProtKB=P03907 P03907 MT-ND4 PTHR43507:SF20 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824 metabolic process#GO:0008152;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;aerobic respiration#GO:0009060;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000003266.3|UniProtKB=G3QL65 G3QL65 WDR5B PTHR22847:SF516 WD40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 5B chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;transcription initiation at RNA polymerase II promoter#GO:0006367;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;chromatin remodeling#GO:0006338;DNA-templated transcription initiation#GO:0006352;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;nucleic acid biosynthetic process#GO:0141187 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;membraneless organelle#GO:0043228;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromosome#GO:0005694;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000010602.3|UniProtKB=G3R4Y0 G3R4Y0 RAD54L PTHR45629:SF17 SNF2/RAD54 FAMILY MEMBER DNA REPAIR AND RECOMBINATION PROTEIN RAD54-LIKE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;nucleobase-containing compound metabolic process#GO:0006139;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;homologous recombination#GO:0035825;reproductive process#GO:0022414;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000007428.3|UniProtKB=G3QWV0 G3QWV0 ERMAP PTHR24100:SF46 BUTYROPHILIN ERYTHROID MEMBRANE-ASSOCIATED PROTEIN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000038355.1|UniProtKB=A0A2I2ZXZ8 A0A2I2ZXZ8 PTHR23087:SF13 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-17 binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000011610.3|UniProtKB=G3R7I7 G3R7I7 DCXR PTHR44252:SF2 D-ERYTHRULOSE REDUCTASE L-XYLULOSE REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 glucose metabolic process#GO:0006006;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000008664.3|UniProtKB=A0A2I2YNJ2 A0A2I2YNJ2 LOC101139132 PTHR26453:SF221 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10D3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007642.3|UniProtKB=G3RNK1 G3RNK1 SLC35G2 PTHR22911:SF52 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000026098.2|UniProtKB=G3RNW8 G3RNW8 ZNF554 PTHR24381:SF56 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 554 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Gene=AFP|UniProtKB=P28050 P28050 AFP PTHR11385:SF7 SERUM ALBUMIN-RELATED ALPHA-FETOPROTEIN binding#GO:0005488;small molecule binding#GO:0036094 response to nutrient levels#GO:0031667;response to stimulus#GO:0050896 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000021983.2|UniProtKB=G3S2N8 G3S2N8 PTHR24291:SF215 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4A11-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;arachidonate metabolic process#GO:0019369;anatomical structure development#GO:0048856;system development#GO:0048731;oxoacid metabolic process#GO:0043436;animal gross anatomical part developmental process#GO:0160108;olefinic compound metabolic process#GO:0120254;icosanoid metabolic process#GO:0006690;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;renal system development#GO:0072001;kidney development#GO:0001822;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;developmental process#GO:0032502;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010536.3|UniProtKB=G3R4R5 G3R4R5 SLC22A13 PTHR24064:SF705 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 13 monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000007491.3|UniProtKB=G3QX05 G3QX05 HHLA2 PTHR24100:SF106 BUTYROPHILIN HERV-H LTR-ASSOCIATING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000038161.1|UniProtKB=A0A2I2ZBN5 A0A2I2ZBN5 MS4A10 PTHR23320:SF5 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 10 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010935.3|UniProtKB=G3S4N5 G3S4N5 CDK10 PTHR24056:SF508 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 10 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 mitotic cell cycle#GO:0000278;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic cell cycle phase transition#GO:0044772;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle G2/M phase transition#GO:1902749;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012792.3|UniProtKB=G3S9A2 G3S9A2 USP10 PTHR24006:SF947 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234 cellular process#GO:0009987;signal transduction#GO:0007165;regulation of protein stability#GO:0031647;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;biological regulation#GO:0065007;DNA damage response#GO:0006974;regulation of catabolic process#GO:0009894;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;regulation of autophagy#GO:0010506;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell communication#GO:0007154 intracellular vesicle#GO:0097708;cytosol#GO:0005829;vesicle#GO:0031982;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000001036.3|UniProtKB=G3QFF0 G3QFF0 MANF PTHR12990:SF10 ARMET-LIKE PROTEIN MESENCEPHALIC ASTROCYTE-DERIVED NEUROTROPHIC FACTOR molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000042919.1|UniProtKB=A0A2I2YXP0 A0A2I2YXP0 PTHR22848:SF3 WD40 REPEAT PROTEIN WD40 REPEAT-CONTAINING PROTEIN SMU1 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904 GORGO|Ensembl=ENSGGOG00000014829.3|UniProtKB=G3RFT5 G3RFT5 SDHAF3 PTHR13137:SF6 DC11 ACN9 HOMOLOG SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 3, MITOCHONDRIAL cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex II assembly#GO:0034553;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000004679.3|UniProtKB=A0A2I2Y853 A0A2I2Y853 ELP2 PTHR44111:SF2 ELONGATOR COMPLEX PROTEIN 2 ELONGATOR COMPLEX PROTEIN 2 intracellular protein-containing complex#GO:0140535;elongator holoenzyme complex#GO:0033588;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000006269.3|UniProtKB=G3QTU2 G3QTU2 FUT5 PTHR11929:SF11 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE FUT5 glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920;transferase activity#GO:0016740;catalytic activity#GO:0003824;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000009625.3|UniProtKB=G3R2E9 G3R2E9 PTHR19872:SF11 UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN TRIPARTITE MOTIF CONTAINING 16 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000034895.2|UniProtKB=G3SKQ2 G3SKQ2 MARS2 PTHR43326:SF8 METHIONYL-TRNA SYNTHETASE METHIONINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000008465.3|UniProtKB=G3RY75 G3RY75 RBAK PTHR24393:SF126 ZINC FINGER PROTEIN RB-ASSOCIATED KRAB ZINC FINGER PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000025881.2|UniProtKB=G3RS00 G3RS00 NFE2L3 PTHR24411:SF8 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 3 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000026850.2|UniProtKB=G3RWC0 G3RWC0 ACSBG2 PTHR43272:SF101 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ACSBG2 catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000008184.3|UniProtKB=G3QYQ9 G3QYQ9 NSMCE2 PTHR21330:SF1 E3 SUMO-PROTEIN LIGASE NSE2 E3 SUMO-PROTEIN LIGASE NSE2 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659 DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;response to stimulus#GO:0050896 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;condensed chromosome#GO:0000793 GORGO|Ensembl=ENSGGOG00000011797.3|UniProtKB=G3R819 G3R819 AUTS2 PTHR14429:SF5 FIBROSIN FAMILY MEMBER AUTISM SUSCEPTIBILITY GENE 2 PROTEIN GORGO|Ensembl=ENSGGOG00000024658.2|UniProtKB=G3RX97 G3RX97 C22H21orf140 PTHR35969:SF1 PROTEIN FAM243A-RELATED SIMILAR TO HUMAN CHROMOSOME 21 OPEN READING FRAME 140 GORGO|Ensembl=ENSGGOG00000001876.3|UniProtKB=A0A2I2ZEG2 A0A2I2ZEG2 RBM46 PTHR21245:SF3 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 46-RELATED RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000021969.2|UniProtKB=G3SBW2 G3SBW2 TBCCD1 PTHR16052:SF4 TBCC DOMAIN-CONTAINING PROTEIN 1 TBCC DOMAIN-CONTAINING PROTEIN 1 cellular localization#GO:0051641;localization#GO:0051179;centrosome localization#GO:0051642;organelle localization#GO:0051640;cellular process#GO:0009987 intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003834.3|UniProtKB=G3QMM3 G3QMM3 GABRP PTHR18945:SF33 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT PI monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215 synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 cell junction#GO:0030054;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;GABA-ergic synapse#GO:0098982;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000041043.1|UniProtKB=G3RXT8 G3RXT8 LOC101131994 PTHR10484:SF210 HISTONE H4 HISTONE H4 structural molecule activity#GO:0005198 chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000016614.3|UniProtKB=G3RKF1 G3RKF1 VWA5B1 PTHR46299:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2-RELATED VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B1 GORGO|Ensembl=ENSGGOG00000013071.3|UniProtKB=G3S4J4 G3S4J4 ZC3H4 PTHR13119:SF23 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity#GO:0001217;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription elongation#GO:0032784;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000010618.3|UniProtKB=G3SCF0 G3SCF0 LRRC41 PTHR15354:SF1 MUF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 41 ubiquitin ligase complex#GO:0000151;Cul5-RING ubiquitin ligase complex#GO:0031466;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Gene=TNP2|UniProtKB=Q9N1A5 Q9N1A5 TNP2 PTHR17488:SF0 NUCLEAR TRANSITION PROTEIN 2 NUCLEAR TRANSITION PROTEIN 2 developmental process#GO:0032502;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;multicellular organismal reproductive process#GO:0048609;single fertilization#GO:0007338;developmental process involved in reproduction#GO:0003006;multi-multicellular organism process#GO:0044706;acrosome reaction#GO:0007340;gamete generation#GO:0007276;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;fertilization#GO:0009566;reproductive process#GO:0022414 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008556.3|UniProtKB=G3QZQ6 G3QZQ6 C8B PTHR45742:SF5 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C8 BETA CHAIN positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;immune response#GO:0006955;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of immune response#GO:0050776 extracellular region#GO:0005576;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 complement component#PC00078 GORGO|Ensembl=ENSGGOG00000005371.3|UniProtKB=G3QRK4 G3QRK4 MEPCE PTHR12315:SF0 BICOID-INTERACTING PROTEIN RELATED 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;snRNA binding#GO:0017069;RNA binding#GO:0003723;binding#GO:0005488;O-methyltransferase activity#GO:0008171;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168 macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 GORGO|Ensembl=ENSGGOG00000000632.3|UniProtKB=A0A2I2ZN79 A0A2I2ZN79 AJAP1 PTHR32422:SF0 ADHERENS JUNCTION-ASSOCIATED PROTEIN 1 ADHERENS JUNCTION-ASSOCIATED PROTEIN 1 binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cytoplasmic side of membrane#GO:0098562;cell-cell contact zone#GO:0044291;anchoring junction#GO:0070161;adherens junction#GO:0005912;side of membrane#GO:0098552;cell junction#GO:0030054;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003185.3|UniProtKB=A0A2I2ZSH0 A0A2I2ZSH0 PPIG PTHR11071:SF292 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000027930.2|UniProtKB=A0A2I2Y7D0 A0A2I2Y7D0 LOC101152385 PTHR11006:SF99 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone modifying activity#GO:0140993;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000026001.2|UniProtKB=G3SHQ2 G3SHQ2 PTHR10064:SF18 60S RIBOSOMAL PROTEIN L22 60S RIBOSOMAL PROTEIN L22 structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012237.3|UniProtKB=G3R966 G3R966 CPT1C PTHR22589:SF55 CARNITINE O-ACYLTRANSFERASE PALMITOYL THIOESTERASE CPT1C acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carnitine metabolic process#GO:0009437;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000027734.2|UniProtKB=A0A2I2YUM1 A0A2I2YUM1 LOC101151835 PTHR11736:SF146 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 11 protein binding#GO:0005515;histone deacetylase binding#GO:0042826;enzyme binding#GO:0019899;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000036327.1|UniProtKB=A0A2I2ZTV9 A0A2I2ZTV9 LOC101152380 PTHR23189:SF110 RNA RECOGNITION MOTIF-CONTAINING RRM DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003595.3|UniProtKB=G3QM08 G3QM08 TMEM26 PTHR22168:SF3 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26 GORGO|Ensembl=ENSGGOG00000037615.1|UniProtKB=A0A2I2ZLF5 A0A2I2ZLF5 PTHR11430:SF1 LIPOCALIN EPIDIDYMAL-SPECIFIC LIPOCALIN-8 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000008154.3|UniProtKB=G3QYN3 G3QYN3 SLC39A10 PTHR12191:SF14 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP10 transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804 intracellular monoatomic ion homeostasis#GO:0006873;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000011089.3|UniProtKB=G3R674 G3R674 CTDP1 PTHR23081:SF36 RNA POLYMERASE II CTD PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Transcription regulation by bZIP transcription factor#P00055>TFIIF#P01394;General transcription regulation#P00023>TFIIF#P00665 GORGO|Ensembl=ENSGGOG00000015184.3|UniProtKB=G3SJP1 G3SJP1 XPNPEP2 PTHR43763:SF4 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 2 protease#PC00190 GORGO|Ensembl=ENSGGOG00000014940.3|UniProtKB=A0A2I2ZKB5 A0A2I2ZKB5 DENND2B PTHR15288:SF5 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2B molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;recycling endosome#GO:0055037 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000005950.3|UniProtKB=G3QT17 G3QT17 MAPKAP1 PTHR13335:SF1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;TORC2 signaling#GO:0038203;biological regulation#GO:0065007;signaling#GO:0023052;TOR signaling#GO:0031929;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;TOR complex#GO:0038201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003298.3|UniProtKB=G3QL93 G3QL93 ANKRA2 PTHR24124:SF3 ANKYRIN REPEAT FAMILY A ANKYRIN REPEAT FAMILY A PROTEIN 2 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000004109.3|UniProtKB=G3QND0 G3QND0 STAG2 PTHR11199:SF3 STROMAL ANTIGEN COHESIN SUBUNIT SA-2 binding#GO:0005488;chromatin binding#GO:0003682 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000026572.2|UniProtKB=G3SDS8 G3SDS8 ASIP PTHR16551:SF1 AGOUTI RELATED AGOUTI-SIGNALING PROTEIN protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;neuropeptide hormone activity#GO:0005184;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;G protein-coupled receptor binding#GO:0001664 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000014797.3|UniProtKB=A0A2I2YX85 A0A2I2YX85 SERINC4 PTHR10383:SF5 SERINE INCORPORATOR SERINE INCORPORATOR 4 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000036714.1|UniProtKB=A0A2I2YE64 A0A2I2YE64 FAM131B PTHR15736:SF9 PROTEIN FAM131B-RELATED PROTEIN FAM131B GORGO|Ensembl=ENSGGOG00000002216.3|UniProtKB=G3QIH4 G3QIH4 TSN PTHR10741:SF2 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000027688.2|UniProtKB=A0A2I2YFI8 A0A2I2YFI8 C1orf52 PTHR31833:SF2 UPF0690 PROTEIN C1ORF52 UPF0690 PROTEIN C1ORF52 GORGO|Ensembl=ENSGGOG00000038641.1|UniProtKB=A0A2I2YVV5 A0A2I2YVV5 ZNF527 PTHR24381:SF400 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 829 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005524.3|UniProtKB=G3QRZ1 G3QRZ1 RNMT PTHR12189:SF2 MRNA GUANINE-7- METHYLTRANSFERASE MRNA CAP GUANINE-N(7) METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000005235.3|UniProtKB=G3QR92 G3QR92 EEA1 PTHR23164:SF30 EARLY ENDOSOME ANTIGEN 1 EARLY ENDOSOME ANTIGEN 1 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 localization#GO:0051179;establishment of localization#GO:0051234;endocytosis#GO:0006897;import into cell#GO:0098657;transport#GO:0006810 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000022686.2|UniProtKB=G3SFE6 G3SFE6 LOC101149119 PTHR20981:SF8 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001999.3|UniProtKB=G3QHY0 G3QHY0 LOC101150488 PTHR14224:SF30 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 7-RELATED ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000037092.1|UniProtKB=A0A2I2YHY6 A0A2I2YHY6 PTHR22573:SF27 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE-LIKE PROTEIN 5 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;metabolic process#GO:0008152;striated muscle tissue development#GO:0014706;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;tissue development#GO:0009888;cellular developmental process#GO:0048869;developmental process#GO:0032502;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;carbohydrate metabolic process#GO:0005975;muscle cell development#GO:0055001;primary metabolic process#GO:0044238;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029 adherens junction#GO:0005912;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;sarcolemma#GO:0042383;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;cell-cell junction#GO:0005911 isomerase#PC00135;metabolite interconversion enzyme#PC00262;mutase#PC00160 GORGO|Ensembl=ENSGGOG00000023179.2|UniProtKB=A0A2I2ZUX4 A0A2I2ZUX4 PTHR11278:SF8 40S RIBOSOMAL PROTEIN S7 40S RIBOSOMAL PROTEIN S7 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;small-subunit processome#GO:0032040;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000036427.1|UniProtKB=A0A2I2ZDU0 A0A2I2ZDU0 PTHR24068:SF360 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 C ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of chromosome segregation#GO:0051983;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of mitotic cell cycle phase transition#GO:1901990;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of mitotic metaphase/anaphase transition#GO:0030071;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000003211.3|UniProtKB=G3SCM0 G3SCM0 LOC101126416 PTHR24291:SF198 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F11 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002555.3|UniProtKB=G3QJC4 G3QJC4 PAX4 PTHR45636:SF8 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;head development#GO:0060322;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008822.3|UniProtKB=G3R0D9 G3R0D9 ST3GAL2 PTHR46032:SF4 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 2 sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000005369.3|UniProtKB=G3SFQ9 G3SFQ9 PAPSS2 PTHR11055:SF16 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;organophosphate biosynthetic process#GO:0090407;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 GORGO|Ensembl=ENSGGOG00000003725.3|UniProtKB=A0A2I2ZWN0 A0A2I2ZWN0 NREP PTHR17102:SF4 NEURONAL REGENERATION-RELATED PROTEIN NEURONAL REGENERATION-RELATED PROTEIN nervous system development#GO:0007399;regeneration#GO:0031099;cellular process#GO:0009987;neuron projection development#GO:0031175;response to stress#GO:0006950;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;cellular response to stress#GO:0033554;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;regulation of neuron differentiation#GO:0045664;axon development#GO:0061564;response to wounding#GO:0009611;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;cellular response to stimulus#GO:0051716;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;system development#GO:0048731;anatomical structure development#GO:0048856 GORGO|Ensembl=ENSGGOG00000002636.3|UniProtKB=G3QJL2 G3QJL2 MYH14 PTHR45615:SF31 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-14 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;actin binding#GO:0003779 regulation of biological process#GO:0050789;cell division#GO:0051301;cell cycle process#GO:0022402;regulation of cell shape#GO:0008360;cell cycle#GO:0007049;cellular component organization#GO:0016043;regulation of developmental process#GO:0050793;actomyosin structure organization#GO:0031032;mitotic cell cycle#GO:0000278;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;actin filament-based process#GO:0030029;cytokinesis#GO:0000910;regulation of biological quality#GO:0065008;cytoskeleton-dependent cytokinesis#GO:0061640;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 GORGO|Ensembl=ENSGGOG00000005142.3|UniProtKB=G3QR04 G3QR04 STARD5 PTHR46374:SF3 PROTEIN CBG07384 STAR-RELATED LIPID TRANSFER PROTEIN 5 sterol transfer activity#GO:0120015;transporter activity#GO:0005215;cholesterol transfer activity#GO:0120020;alcohol binding#GO:0043178;steroid binding#GO:0005496;small molecule binding#GO:0036094;binding#GO:0005488;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;sterol binding#GO:0032934;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;cholesterol binding#GO:0015485 lipid transport#GO:0006869;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;sterol transport#GO:0015918;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876 GORGO|Ensembl=ENSGGOG00000022628.2|UniProtKB=G3S6F6 G3S6F6 PTHR16471:SF2 CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN-LIKE PROTEIN SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000003033.3|UniProtKB=G3QKK9 G3QKK9 E2F2 PTHR12081:SF50 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000016714.3|UniProtKB=G3RKP4 G3RKP4 TSPOAP1 PTHR14234:SF20 RIM BINDING PROTEIN-RELATED PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005486.3|UniProtKB=G3QRX0 G3QRX0 ITPR1 PTHR45816:SF2 MIR DOMAIN-CONTAINING PROTEIN INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR Histamine H1 receptor mediated signaling pathway#P04385>IP3R#P04486;Metabotropic glutamate receptor group I pathway#P00041>IP3R#P01056;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IP3R#P00842;Endothelin signaling pathway#P00019>IP3 R#P00590;Alpha adrenergic receptor signaling pathway#P00002>IP3R#P00076;PDGF signaling pathway#P00047>IP3 receptor#P01160;Wnt signaling pathway#P00057>IP3 Gated Calcium Channel#P01426;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>IP3R#P01064 GORGO|Ensembl=ENSGGOG00000007996.3|UniProtKB=A0A2I2YL44 A0A2I2YL44 PAQR3 PTHR20855:SF15 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;macromolecule localization#GO:0033036;protein localization to Golgi apparatus#GO:0034067 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005070.3|UniProtKB=G3QQU5 G3QQU5 CNOT11 PTHR15975:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 CCR4-NOT complex#GO:0030014;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000014136.3|UniProtKB=A0A2I2YVU5 A0A2I2YVU5 TUFM PTHR43721:SF36 ELONGATION FACTOR TU-RELATED ELONGATION FACTOR TU, MITOCHONDRIAL translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000008322.3|UniProtKB=G3RVF3 G3RVF3 PLA2R1 PTHR22803:SF74 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED SECRETORY PHOSPHOLIPASE A2 RECEPTOR transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000007403.3|UniProtKB=G3QWT3 G3QWT3 ACIN1 PTHR46589:SF1 APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000002101.3|UniProtKB=G3QI65 G3QI65 SLC6A20 PTHR11616:SF44 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT TRANSPORTER XTRP3 transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324 L-alpha-amino acid transmembrane transport#GO:1902475;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;glycine transport#GO:0015816;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 GORGO|Ensembl=ENSGGOG00000016522.3|UniProtKB=G3RK57 G3RK57 LAMTOR5 PTHR13342:SF4 RAGULATOR COMPLEX PROTEIN LAMTOR5 RAGULATOR COMPLEX PROTEIN LAMTOR5 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;positive regulation of TORC1 signaling#GO:1904263;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000023754.2|UniProtKB=G3S4B3 G3S4B3 SGTB PTHR45831:SF1 LD24721P SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN BETA localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000004285.3|UniProtKB=A0A2I2YAK7 A0A2I2YAK7 CDC42BPB PTHR22988:SF34 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE MRCK BETA protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000007162.3|UniProtKB=G3QW55 G3QW55 KCNMB1 PTHR10258:SF1 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-1 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 detection of chemical stimulus#GO:0009593;action potential#GO:0001508;response to stimulus#GO:0050896;metal ion transport#GO:0030001;nervous system process#GO:0050877;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;response to calcium ion#GO:0051592;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;detection of stimulus#GO:0051606;cellular process#GO:0009987;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;potassium ion transport#GO:0006813;biological regulation#GO:0065007;transport#GO:0006810;response to metal ion#GO:0010038;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;system process#GO:0003008;transmission of nerve impulse#GO:0019226 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000042820.1|UniProtKB=A0A2I2Y6R9 A0A2I2Y6R9 PTHR11193:SF8 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;spliceosomal snRNP assembly#GO:0000387;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043 ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2 snRNP#GO:0005686;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytoplasm#GO:0005737 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000013563.3|UniProtKB=G3RCK2 G3RCK2 EXO1 PTHR11081:SF8 FLAP ENDONUCLEASE FAMILY MEMBER EXONUCLEASE 1 hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000002181.3|UniProtKB=G3QIE2 G3QIE2 FRMD4B PTHR46079:SF1 FERM DOMAIN-CONTAINING PROTEIN 4 FERM DOMAIN-CONTAINING PROTEIN 4B adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 GORGO|Ensembl=ENSGGOG00000023682.2|UniProtKB=G3SCR5 G3SCR5 PTHR15222:SF3 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 SUBFAMILY NOT NAMED catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Gene=TAS2R19|UniProtKB=Q645Z9 Q645Z9 TAS2R19 PTHR11394:SF139 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 19-RELATED transmembrane signaling receptor activity#GO:0004888;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of taste#GO:0050909;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012195.3|UniProtKB=G3R921 G3R921 MEIOC PTHR33861:SF3 PROTEIN CBG18333 MEIOSIS-SPECIFIC COILED-COIL DOMAIN-CONTAINING PROTEIN MEIOC regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;RNA stabilization#GO:0043489;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nuclear division#GO:0000280;mRNA stabilization#GO:0048255;male meiotic nuclear division#GO:0007140;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell cycle#GO:0007049;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;organelle fission#GO:0048285;positive regulation of biosynthetic process#GO:0009891;sexual reproduction#GO:0019953;regulation of RNA stability#GO:0043487;meiosis I cell cycle process#GO:0061982;biological regulation#GO:0065007;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;meiotic nuclear division#GO:0140013;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000023625.2|UniProtKB=G3SEA0 G3SEA0 MATCAP1 PTHR31817:SF1 FAMILY NOT NAMED MICROTUBULE-ASSOCIATED TYROSINE CARBOXYPEPTIDASE 1 GORGO|Ensembl=ENSGGOG00000012494.3|UniProtKB=G3R9T8 G3R9T8 KLF11 PTHR23235:SF65 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 11 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009912.3|UniProtKB=G3R364 G3R364 CHI3L1 PTHR11177:SF202 CHITINASE CHITINASE-3-LIKE PROTEIN 1 catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002129.3|UniProtKB=G3QI92 G3QI92 PIP4P1 PTHR21014:SF2 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE TYPE 1 PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 4-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;dephosphorylation#GO:0016311;lipid modification#GO:0030258 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;late endosome membrane#GO:0031902 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000037735.1|UniProtKB=A0A2I2YLM3 A0A2I2YLM3 PTHR37553:SF10 DUF4705 DOMAIN-CONTAINING PROTEIN DUF4705 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000009303.3|UniProtKB=G3R1K9 G3R1K9 KRTCAP2 PTHR32001:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 2 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT KCP2 biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 GORGO|Ensembl=ENSGGOG00000043321.1|UniProtKB=A0A2I2ZAH3 A0A2I2ZAH3 LOC101125083 PTHR34260:SF1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex III assembly#GO:0034551;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000003846.3|UniProtKB=G3QMN5 G3QMN5 FCGR2A PTHR11481:SF106 IMMUNOGLOBULIN FC RECEPTOR LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR II-A signaling receptor activity#GO:0038023;protein-containing complex binding#GO:0044877;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of endocytosis#GO:0045807;adaptive immune response#GO:0002250;biological regulation#GO:0065007;cell killing#GO:0001906;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of gene expression#GO:0010628;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;inflammatory response#GO:0006954;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;acute inflammatory response#GO:0002526;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879;leukocyte mediated cytotoxicity#GO:0001909;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of cellular component organization#GO:0051130;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000016946.3|UniProtKB=G3RZ84 G3RZ84 IGFBP5 PTHR11551:SF4 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 5 protein binding#GO:0005515;growth factor binding#GO:0019838;binding#GO:0005488 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000002853.3|UniProtKB=G3QK40 G3QK40 ITLN1 PTHR16146:SF38 INTELECTIN INTELECTIN-1 oligosaccharide binding#GO:0070492;binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013262.3|UniProtKB=A0A2I2Z7M2 A0A2I2Z7M2 LOC101131416 PTHR14882:SF6 COILED-COIL DOMAIN-CONTAINING 74A CCDC92_74 N-TERMINAL DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000005842.3|UniProtKB=G3QSS6 G3QSS6 PTHR11890:SF23 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR ACCESSORY PROTEIN cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000017119.3|UniProtKB=G3RLP8 G3RLP8 ZNF585B PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010150.3|UniProtKB=G3R3S9 G3R3S9 ESRP2 PTHR13976:SF30 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED EPITHELIAL SPLICING REGULATORY PROTEIN 2 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000006492.3|UniProtKB=A0A2I2ZBK5 A0A2I2ZBK5 INSYN2A PTHR28682:SF1 INHIBITORY SYNAPTIC FACTOR 2A-RELATED INHIBITORY SYNAPTIC FACTOR 2A regulation of biological quality#GO:0065008;cell communication#GO:0007154;nervous system process#GO:0050877;trans-synaptic signaling#GO:0099537;chemical synaptic transmission, postsynaptic#GO:0099565;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;regulation of postsynaptic membrane potential#GO:0060078;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;system process#GO:0003008;regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536 postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202 GORGO|Ensembl=ENSGGOG00000027981.2|UniProtKB=A0A2I2Y1K5 A0A2I2Y1K5 C22H21orf91 PTHR15961:SF3 PROTEIN EURL HOMOLOG PROTEIN EURL HOMOLOG central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;neuron differentiation#GO:0030182;positive regulation of developmental process#GO:0051094;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;multicellular organismal process#GO:0032501;brain development#GO:0007420;nervous system development#GO:0007399;head development#GO:0060322;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological process#GO:0050789;forebrain development#GO:0030900;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of developmental process#GO:0050793 GORGO|Ensembl=ENSGGOG00000041745.1|UniProtKB=A0A2I2Y3F4 A0A2I2Y3F4 PTHR19339:SF0 T CELL RECEPTOR ALPHA VARIABLE 39 T CELL RECEPTOR ALPHA VARIABLE 41 GORGO|Ensembl=ENSGGOG00000014311.3|UniProtKB=G3REH0 G3REH0 MFSD3 PTHR12778:SF10 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED SOLUTE CARRIER FAMILY 33 MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008735.3|UniProtKB=G3R062 G3R062 ACBD6 PTHR24119:SF0 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;enzyme activator activity#GO:0008047;heterocyclic compound binding#GO:1901363;molecular function regulator activity#GO:0098772 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000002598.3|UniProtKB=G3QJG4 G3QJG4 XCL2 PTHR12015:SF101 SMALL INDUCIBLE CYTOKINE A CYTOKINE SCM-1 BETA-RELATED chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009 signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;response to peptide#GO:1901652;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;taxis#GO:0042330;response to cytokine#GO:0034097;response to chemical#GO:0042221;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;response to stress#GO:0006950;cell surface receptor signaling pathway#GO:0007166;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell chemotaxis#GO:0060326;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;regulation of cell motility#GO:2000145;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;cell migration#GO:0016477;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000006159.3|UniProtKB=G3QTJ8 G3QTJ8 PNMA1 PTHR23095:SF17 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN MA1 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000006870.3|UniProtKB=Q8SQ79 Q8SQ79 COX8A PTHR16717:SF1 CYTOCHROME C OXIDASE POLYPEPTIDE VIII CYTOCHROME C OXIDASE SUBUNIT 8A, MITOCHONDRIAL transporter complex#GO:1990351;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009542.3|UniProtKB=G3R277 G3R277 KCNE2 PTHR15282:SF8 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 2 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;potassium channel regulator activity#GO:0015459;voltage-gated potassium channel activity#GO:0005249;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;transmembrane transporter binding#GO:0044325 cardiac muscle cell action potential involved in contraction#GO:0086002;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;export from cell#GO:0140352;regulation of biological process#GO:0050789;muscle system process#GO:0003012;action potential#GO:0001508;heart process#GO:0003015;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;blood circulation#GO:0008015;potassium ion transport#GO:0006813;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;actin filament-based movement#GO:0030048;establishment of localization#GO:0051234;cardiac muscle cell contraction#GO:0086003;system process#GO:0003008;heart contraction#GO:0060047;regulation of system process#GO:0044057;muscle contraction#GO:0006936;transport#GO:0006810;actin-mediated cell contraction#GO:0070252;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;regulation of heart contraction#GO:0008016;monoatomic cation transport#GO:0006812;localization#GO:0051179;circulatory system process#GO:0003013;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000023058.2|UniProtKB=G3S3D1 G3S3D1 C12H2orf74 PTHR37882:SF1 HYPOTHETICAL PROTEIN LOC690352 SIMILAR TO HUMAN CHROMOSOME 2 OPEN READING FRAME 74 GORGO|Ensembl=ENSGGOG00000010585.3|UniProtKB=A0A2I2Z785 A0A2I2Z785 VPS53 PTHR12820:SF0 VACUOLAR SORTING PROTEIN 53 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000003626.3|UniProtKB=A0A2I2ZJF9 A0A2I2ZJF9 MOXD1 PTHR10157:SF28 DOPAMINE BETA HYDROXYLASE RELATED DBH-LIKE MONOOXYGENASE PROTEIN 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;extracellular region#GO:0005576;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 hydroxylase#PC00122 GORGO|Gene=ELAC2|UniProtKB=Q9GL73 Q9GL73 ELAC2 PTHR12553:SF49 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;tRNA 3'-end processing#GO:0042780;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000014963.3|UniProtKB=G3RG64 G3RG64 LRRC71 PTHR46984:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71 GORGO|Ensembl=ENSGGOG00000006465.3|UniProtKB=G3QUC1 G3QUC1 LOC109024094 PTHR11738:SF196 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR-LIKE PROTEIN KIR3DX1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000002705.3|UniProtKB=G3QJR5 G3QJR5 ERCC6L2 PTHR45629:SF14 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 2 response to stimulus#GO:0050896;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000027593.2|UniProtKB=G3RN73 G3RN73 CT83 PTHR38650:SF1 KITA-KYUSHU LUNG CANCER ANTIGEN 1 KITA-KYUSHU LUNG CANCER ANTIGEN 1 GORGO|Ensembl=ENSGGOG00000000485.3|UniProtKB=G3S0W3 G3S0W3 PITPNM2 PTHR10658:SF41 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN MEMBRANE-ASSOCIATED PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 2 lipid binding#GO:0008289;lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;binding#GO:0005488;transporter activity#GO:0005215;cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303;lipid carrier activity#GO:0005319;ion binding#GO:0043167;phosphatidylcholine intramembrane carrier activity#GO:0008525;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine binding#GO:0031210;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004631.3|UniProtKB=G3SAU5 G3SAU5 HOPX PTHR21408:SF1 HOMEODOMAIN-ONLY PROTEIN HOMEODOMAIN-ONLY PROTEIN molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000007705.3|UniProtKB=G3S8L4 G3S8L4 TMEM8B PTHR14319:SF6 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 TRANSMEMBRANE PROTEIN 8B cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000028552.2|UniProtKB=G3SK06 G3SK06 FTSJ1 PTHR10920:SF12 RIBOSOMAL RNA METHYLTRANSFERASE TRNA (CYTIDINE(32)_GUANOSINE(34)-2'-O)-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000034865.2|UniProtKB=G3SKF8 G3SKF8 PTHR23031:SF5 RHOPHILIN RHOPHILIN-2-RELATED negative regulation of cytoskeleton organization#GO:0051494;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of actin filament bundle assembly#GO:0032231;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament organization#GO:0110053;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005282.3|UniProtKB=A0A2I2Z7T6 A0A2I2Z7T6 TSHZ2 PTHR12487:SF3 TEASHIRT-RELATED TEASHIRT HOMOLOG 2 DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000002750.3|UniProtKB=G3QJV6 G3QJV6 RGS2 PTHR10845:SF43 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 2 GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of cell communication#GO:0010648 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 CCKR signaling map#P06959>RGS2#P07040;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 GORGO|Ensembl=ENSGGOG00000040815.1|UniProtKB=A0A2I2YLX4 A0A2I2YLX4 TDRD10 PTHR22948:SF12 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 10 binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000034841.2|UniProtKB=G3SKD5 G3SKD5 RINT1 PTHR13520:SF0 RAD50-INTERACTING PROTEIN 1 RINT-1 RAD50-INTERACTING PROTEIN 1 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000000940.3|UniProtKB=G3QF60 G3QF60 KHDRBS3 PTHR11208:SF29 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 3 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000034807.2|UniProtKB=G3SKT9 G3SKT9 KCNH5 PTHR10217:SF533 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH5 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025031.2|UniProtKB=G3RVB9 G3RVB9 PTHR11831:SF48 30S 40S RIBOSOMAL PROTEIN SMALL RIBOSOMAL SUBUNIT PROTEIN US4 structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843 ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016907.3|UniProtKB=G3RL58 G3RL58 S100A14 PTHR11639:SF4 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A14 ion binding#GO:0043167;binding#GO:0005488;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;cytokine receptor binding#GO:0005126;calcium ion binding#GO:0005509;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;metal ion binding#GO:0046872;cation binding#GO:0043169;G protein-coupled receptor binding#GO:0001664 regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;immune response-regulating signaling pathway#GO:0002764;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;response to lipid#GO:0033993;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;response to external biotic stimulus#GO:0043207;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831;regulation of leukocyte migration#GO:0002685;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of granulocyte chemotaxis#GO:0071622;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;response to bacterium#GO:0009617;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of chemotaxis#GO:0050921;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;positive regulation of cell migration#GO:0030335;activation of innate immune response#GO:0002218;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;toll-like receptor 4 signaling pathway#GO:0034142;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of locomotion#GO:0040017;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088 extracellular region#GO:0005576;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000004136.3|UniProtKB=G3QNE6 G3QNE6 SLC16A9 PTHR11360:SF158 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 9 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016337.3|UniProtKB=A0A2I2YZD6 A0A2I2YZD6 SYNPO PTHR24217:SF13 PUTATIVE-RELATED SYNAPTOPODIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of small GTPase mediated signal transduction#GO:0051056;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;actomyosin structure organization#GO:0031032;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of Rho protein signal transduction#GO:0035023;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;regulation of actin filament bundle assembly#GO:0032231;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;striated muscle cell development#GO:0055002;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;positive regulation of actin filament bundle assembly#GO:0032233;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of actin filament-based process#GO:0032970;regulation of cell communication#GO:0010646;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927 Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;neuron to neuron synapse#GO:0098984;glutamatergic synapse#GO:0098978;supramolecular polymer#GO:0099081;postsynaptic specialization#GO:0099572;supramolecular complex#GO:0099080;I band#GO:0031674;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;sarcomere#GO:0030017;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000007952.3|UniProtKB=G3QY49 G3QY49 CLPSL1 PTHR10041:SF7 COLIPASE COLIPASE-LIKE PROTEIN 1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000000617.3|UniProtKB=G3QEB6 G3QEB6 SYNDIG1 PTHR14768:SF3 UPF0338 PROTEIN SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1 vesicle localization#GO:0051648;positive regulation of cellular process#GO:0048522;regulation of synapse assembly#GO:0051963;biological regulation#GO:0065007;positive regulation of developmental process#GO:0051094;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;positive regulation of synapse assembly#GO:0051965;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;organelle localization#GO:0051640;regulation of cell junction assembly#GO:1901888;localization#GO:0051179;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;regulation of multicellular organismal process#GO:0051239;vesicle-mediated transport in synapse#GO:0099003;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of cellular component biogenesis#GO:0044087;positive regulation of cellular component organization#GO:0051130;regulation of synapse organization#GO:0050807;cellular localization#GO:0051641;regulation of biological quality#GO:0065008 membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;neuron to neuron synapse#GO:0098984;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;organelle membrane#GO:0031090;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;asymmetric synapse#GO:0032279;intracellular membrane-bounded organelle#GO:0043231;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;synaptic membrane#GO:0097060;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008206.3|UniProtKB=G3S9C2 G3S9C2 ZIM3 PTHR24404:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 835 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005607.3|UniProtKB=G3QS62 G3QS62 NR1H2 PTHR48092:SF2 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 1, GROUP H, MEMBER 3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000014438.3|UniProtKB=G3RET9 G3RET9 GALNT10 PTHR11675:SF41 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 10 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000009025.3|UniProtKB=G3SE27 G3SE27 PBX3 PTHR11850:SF97 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 3 transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837 neuron development#GO:0048666;eye development#GO:0001654;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;head development#GO:0060322;nervous system development#GO:0007399;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;sensory system development#GO:0048880;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;embryonic organ development#GO:0048568;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000027438.3|UniProtKB=G3RZ39 G3RZ39 SUCLG2 PTHR11815:SF12 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;energy derivation by oxidation of organic compounds#GO:0015980 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000017038.3|UniProtKB=G3RLI0 G3RLI0 ICA1L PTHR10164:SF5 ISLET CELL AUTOANTIGEN 1 ISLET CELL AUTOANTIGEN 1-LIKE PROTEIN molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 cellular component organization or biogenesis#GO:0071840;regulation of secretion#GO:0051046;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;biological regulation#GO:0065007;membrane organization#GO:0061024 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000003013.4|UniProtKB=G3QKJ3 G3QKJ3 PTHR13265:SF2 THO COMPLEX SUBUNIT 1 THO COMPLEX SUBUNIT 1 metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010032.3|UniProtKB=G3R3H8 G3R3H8 RAD54L2 PTHR45797:SF1 RAD54-LIKE HELICASE ARIP4 transcription regulator activity#GO:0140110;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000000939.3|UniProtKB=G3QF61 G3QF61 NDC80 PTHR10643:SF2 KINETOCHORE PROTEIN NDC80 KINETOCHORE PROTEIN NDC80 HOMOLOG chromosome localization#GO:0050000;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;attachment of spindle microtubules to kinetochore#GO:0008608;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;mitotic metaphase chromosome alignment#GO:0007080;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;localization#GO:0051179;organelle fission#GO:0048285;nuclear division#GO:0000280;organelle localization#GO:0051640;attachment of mitotic spindle microtubules to kinetochore#GO:0051315 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000003963.3|UniProtKB=A0A2I2Z4L4 A0A2I2Z4L4 IMPDH PTHR11911:SF74 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 nucleoside phosphate biosynthetic process#GO:1901293;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 GORGO|Ensembl=ENSGGOG00000013985.3|UniProtKB=G3RDN1 G3RDN1 PCBD1 PTHR12599:SF13 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 lyase#PC00144;dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000012037.3|UniProtKB=G3R8M6 G3R8M6 PTHR21585:SF0 FULL-LENGTH CDNA CLONE CS0DC025YL05 OF NEUROBLASTOMA ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000006973.3|UniProtKB=A0A2I2YK06 A0A2I2YK06 DZIP3 PTHR15727:SF4 RING FINGER PROTEIN 214 E3 UBIQUITIN-PROTEIN LIGASE DZIP3 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;polyubiquitin modification-dependent protein binding#GO:0031593;ubiquitin-protein transferase activity#GO:0004842;RNA binding#GO:0003723;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;binding#GO:0005488;modification-dependent protein binding#GO:0140030 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000001189.3|UniProtKB=G3S6E7 G3S6E7 ACTMAP PTHR28631:SF1 UPF0692 PROTEIN C19ORF54 ACTIN MATURATION PROTEASE aminopeptidase activity#GO:0004177;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 GORGO|Ensembl=ENSGGOG00000004287.3|UniProtKB=G3QNS9 G3QNS9 EMG1 PTHR12636:SF5 NEP1/MRA1 RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1 catalytic activity, acting on a rRNA#GO:0140102;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;rRNA binding#GO:0019843;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;methylation#GO:0032259;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;rRNA base methylation#GO:0070475;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040 transferase#PC00220;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000011173.3|UniProtKB=G3R6E6 G3R6E6 AZIN1 PTHR11482:SF7 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ANTIZYME INHIBITOR 1 ornithine decarboxylase activity#GO:0004586;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;lyase activity#GO:0016829;molecular function regulator activity#GO:0098772;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;carboxy-lyase activity#GO:0016831 negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of catabolic process#GO:0009894;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;amine metabolic process#GO:0009308;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;negative regulation of protein catabolic process#GO:0042177;polyamine biosynthetic process#GO:0006596;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;regulation of biological process#GO:0050789;polyamine metabolic process#GO:0006595;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 GORGO|Ensembl=ENSGGOG00000026427.2|UniProtKB=A0A2I2Z4L5 A0A2I2Z4L5 AIFM3 PTHR43557:SF8 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219;execution phase of apoptosis#GO:0097194;programmed cell death#GO:0012501 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000008320.3|UniProtKB=G3QZ29 G3QZ29 LOC101138925 PTHR26453:SF237 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2C1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015129.3|UniProtKB=A0A2I2Z9J5 A0A2I2Z9J5 STS PTHR42693:SF9 ARYLSULFATASE FAMILY MEMBER STERYL-SULFATASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000007556.3|UniProtKB=G3SGD5 G3SGD5 PPP3CB PTHR45673:SF7 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT BETA ISOFORM phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;protein binding#GO:0005515;hydrolase activity#GO:0016787;binding#GO:0005488 intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;calcineurin-mediated signaling#GO:0097720 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 protein phosphatase#PC00195 Wnt signaling pathway#P00057>Calcineurin#P01446;T cell activation#P00053>Calcineurin#P01315;B cell activation#P00010>Calcineurin#P00386 GORGO|Ensembl=ENSGGOG00000004334.4|UniProtKB=A0A2I2YDJ3 A0A2I2YDJ3 NR3C1 PTHR48092:SF5 KNIRPS-RELATED PROTEIN-RELATED GLUCOCORTICOID RECEPTOR DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;response to steroid hormone#GO:0048545;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;cellular response to steroid hormone stimulus#GO:0071383;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>GR#P06810 GORGO|Ensembl=ENSGGOG00000010895.3|UniProtKB=G3R5N6 G3R5N6 PRRG1 PTHR24278:SF37 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 1 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000007199.4|UniProtKB=G3QWA1 G3QWA1 STXBP3 PTHR11679:SF33 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 3 protein binding#GO:0005515;syntaxin binding#GO:0019905;binding#GO:0005488;SNARE binding#GO:0000149 vesicle localization#GO:0051648;macromolecule localization#GO:0033036;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;calcium-ion regulated exocytosis#GO:0017156;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;synaptic signaling#GO:0099536;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;regulation of biological process#GO:0050789;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656;secretion by cell#GO:0032940;protein transport#GO:0015031;cellular localization#GO:0051641 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000002966.3|UniProtKB=G3QKE4 G3QKE4 PTHR46939:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000011516.3|UniProtKB=G3R796 G3R796 GUCA2A PTHR11318:SF3 GUANYLIN FAMILY MEMBER GUANYLIN cyclase regulator activity#GO:0010851;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000025887.2|UniProtKB=A0A2I2ZE50 A0A2I2ZE50 PTHR43205:SF25 PROSTAGLANDIN REDUCTASE 15-OXOPROSTAGLANDIN 13-REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 lipid metabolic process#GO:0006629;prostaglandin metabolic process#GO:0006693;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;long-chain fatty acid metabolic process#GO:0001676 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000012489.3|UniProtKB=G3R9U6 G3R9U6 ENO4 PTHR11902:SF30 ENOLASE ENOLASE 4 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824;phosphopyruvate hydratase activity#GO:0004634 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000008766.3|UniProtKB=G3R088 G3R088 PDE6H PTHR12122:SF5 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;positive regulation of signal transduction#GO:0009967;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cell projection membrane#GO:0031253;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;plasma membrane region#GO:0098590;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000005405.3|UniProtKB=A0A2I2YIG6 A0A2I2YIG6 ADGRE5 PTHR12011:SF348 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E5 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000009036.3|UniProtKB=G3R0Y3 G3R0Y3 LOC101138121 PTHR15712:SF6 ARMADILLO REPEAT CONTAINING PROTEIN PROTEIN ARMCX6 transport#GO:0006810;intracellular transport#GO:0046907;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;axo-dendritic transport#GO:0008088;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;axonal transport#GO:0098930;organelle localization#GO:0051640;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014751.3|UniProtKB=G3RSC2 G3RSC2 TBC1D2 PTHR22957:SF570 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 2A molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000001386.3|UniProtKB=A0A2I2Z707 A0A2I2Z707 RGS20 PTHR10845:SF277 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 20 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583 cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 GORGO|Ensembl=ENSGGOG00000015591.3|UniProtKB=A0A2I2YSQ9 A0A2I2YSQ9 KIF22 PTHR24115:SF1037 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF22 cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000004951.3|UniProtKB=G3QQI2 G3QQI2 VAMP5 PTHR47462:SF1 VESICLE-ASSOCIATED MEMBRANE PROTEIN 5 VESICLE-ASSOCIATED MEMBRANE PROTEIN 5 localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;Golgi vesicle transport#GO:0048193;transport#GO:0006810;protein localization to cell periphery#GO:1990778;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000010807.3|UniProtKB=G3SHS8 G3SHS8 LOC101144699 PTHR16675:SF154 MHC CLASS I-RELATED MHC CLASS I POLYPEPTIDE-RELATED SEQUENCE A-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823 regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;cell activation#GO:0001775;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;T cell activation#GO:0042110;leukocyte activation#GO:0045321;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000007323.3|UniProtKB=G3QWK6 G3QWK6 ARMC5 PTHR23312:SF8 ARMC5 ARMADILLO REPEAT-CONTAINING -RELATED ARMADILLO REPEAT-CONTAINING PROTEIN 5 anatomical structure development#GO:0048856;developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653 GORGO|Ensembl=ENSGGOG00000027565.2|UniProtKB=G3SCL4 G3SCL4 MPC2 PTHR14154:SF154 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 2 monocarboxylic acid transmembrane transporter activity#GO:0008028;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transmembrane transport#GO:0055085;monocarboxylic acid transport#GO:0015718;intracellular transport#GO:0046907;carboxylic acid transport#GO:0046942;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;organic acid transport#GO:0015849 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000013870.3|UniProtKB=G3RDC6 G3RDC6 CNN3 PTHR46756:SF4 TRANSGELIN CALPONIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;supramolecular fiber organization#GO:0097435;regulation of microtubule-based process#GO:0032886;microtubule bundle formation#GO:0001578;actin filament-based process#GO:0030029;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;actin filament organization#GO:0007015;protein localization to microtubule cytoskeleton#GO:0072698;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;actomyosin#GO:0042641;microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;stress fiber#GO:0001725;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;microtubule end#GO:1990752;microtubule#GO:0005874;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000028183.2|UniProtKB=A0A2I2YRQ8 A0A2I2YRQ8 ZNF540 PTHR24381:SF480 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 59 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000006828.3|UniProtKB=A0A2I2YCS3 A0A2I2YCS3 IL12A PTHR48485:SF1 INTERLEUKIN-12 SUBUNIT BETA-RELATED INTERLEUKIN-12 SUBUNIT ALPHA cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;protein binding#GO:0005515;molecular function activator activity#GO:0140677;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 GORGO|Ensembl=ENSGGOG00000003028.3|UniProtKB=G3SIA9 G3SIA9 TBC1D9B PTHR22957:SF225 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 9B enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000016243.3|UniProtKB=G3RJF8 G3RJF8 POU2F1 PTHR11636:SF47 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>OCT-1#P06720 GORGO|Ensembl=ENSGGOG00000003749.3|UniProtKB=G3QME2 G3QME2 NNMT PTHR10867:SF52 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 GORGO|Ensembl=ENSGGOG00000015607.3|UniProtKB=G3RHU5 G3RHU5 RASL10B PTHR46350:SF1 RAS LIKE FAMILY 10 MEMBER B-RELATED RAS-LIKE PROTEIN FAMILY MEMBER 10B GORGO|Ensembl=ENSGGOG00000002504.3|UniProtKB=G3QJ84 G3QJ84 PTHR10668:SF103 PHYTOENE DEHYDROGENASE PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000038627.1|UniProtKB=A0A2I2YTW9 A0A2I2YTW9 ZNF486 PTHR24384:SF95 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 486 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000025074.2|UniProtKB=G3RMJ5 G3RMJ5 AHCYL2 PTHR23420:SF2 ADENOSYLHOMOCYSTEINASE S-ADENOSYLHOMOCYSTEINE HYDROLASE-LIKE PROTEIN 2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000027071.2|UniProtKB=G3SAE4 G3SAE4 PPIL1 PTHR45625:SF7 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000014750.3|UniProtKB=G3RFM2 G3RFM2 EDF1 PTHR10245:SF15 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 GORGO|Ensembl=ENSGGOG00000011246.3|UniProtKB=G3R6K1 G3R6K1 MED9 PTHR20844:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9 core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000008475.3|UniProtKB=G3QZH4 G3QZH4 LHX2 PTHR24208:SF80 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>LHX2#P06756 GORGO|Ensembl=ENSGGOG00000016506.3|UniProtKB=G3RK46 G3RK46 WNT16 PTHR12027:SF70 WNT RELATED PROTEIN WNT-16 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125 cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell fate commitment#GO:0045165;system development#GO:0048731 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 GORGO|Ensembl=ENSGGOG00000009366.4|UniProtKB=A0A2I2ZIK5 A0A2I2ZIK5 PDE1A PTHR11347:SF34 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1A catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585 cell body#GO:0044297;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025 hydrolase#PC00121;phosphodiesterase#PC00185 CCKR signaling map#P06959>PDE#P07161 GORGO|Ensembl=ENSGGOG00000027544.2|UniProtKB=G3RT48 G3RT48 GOLPH3 PTHR12704:SF3 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3 phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312;lipid binding#GO:0008289;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674 establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi organization#GO:0007030;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000038281.1|UniProtKB=A0A2I2YXD8 A0A2I2YXD8 KLRF2 PTHR46746:SF6 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY F MEMBER 2 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY F MEMBER 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025004.2|UniProtKB=G3RMI7 G3RMI7 DCTPP1 PTHR46523:SF1 DCTP PYROPHOSPHATASE 1 DCTP PYROPHOSPHATASE 1 nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462 cellular response to stress#GO:0033554;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleotide catabolic process#GO:0009166;macromolecule metabolic process#GO:0043170;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;response to stress#GO:0006950;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000005909.3|UniProtKB=G3QSY3 G3QSY3 MPHOSPH8 PTHR24173:SF95 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013259.3|UniProtKB=G3SI09 G3SI09 CHAC1 PTHR12192:SF26 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1 lyase activity#GO:0016829;catalytic activity#GO:0003824 sulfur compound catabolic process#GO:0044273;catabolic process#GO:0009056;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000016413.3|UniProtKB=A0A2I2Z0M2 A0A2I2Z0M2 ZNF428 PTHR36862:SF1 ZINC FINGER PROTEIN 428 ZINC FINGER PROTEIN 428 GORGO|Ensembl=ENSGGOG00000007891.3|UniProtKB=G3QY04 G3QY04 CSGALNACT2 PTHR12369:SF20 CHONDROITIN SYNTHASE CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000022915.2|UniProtKB=A0A2I2ZJ74 A0A2I2ZJ74 MRPL48 PTHR13473:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L48 LARGE RIBOSOMAL SUBUNIT PROTEIN ML48 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010651.3|UniProtKB=A0A2I2YIR5 A0A2I2YIR5 ANTXRL PTHR16059:SF16 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000007961.3|UniProtKB=G3QY54 G3QY54 CTLA4 PTHR11494:SF8 CYTOTOXIC T-LYMPHOCYTE PROTEIN CYTOTOXIC T-LYMPHOCYTE PROTEIN 4 negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of developmental process#GO:0050793;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;negative regulation of multicellular organismal process#GO:0051241;cell communication#GO:0007154;regulation of hemopoiesis#GO:1903706;regulation of immune response#GO:0050776;negative regulation of T cell activation#GO:0050868;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;positive regulation of response to stimulus#GO:0048584;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;regulation of cell development#GO:0060284;negative regulation of cell activation#GO:0050866;positive regulation of immune response#GO:0050778;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;immune response-regulating signaling pathway#GO:0002764;regulation of multicellular organismal development#GO:2000026;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;immune system process#GO:0002376;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell-cell adhesion#GO:0022408;antigen receptor-mediated signaling pathway#GO:0050851;regulation of T cell activation#GO:0050863;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;B cell receptor signaling pathway#GO:0050853;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000004446.3|UniProtKB=G3QP75 G3QP75 ATP6V1A PTHR43607:SF9 V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;lysosome#GO:0005764;cation-transporting ATPase complex#GO:0090533;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000003201.3|UniProtKB=A0A2I2YZP1 A0A2I2YZP1 RFT1 PTHR13117:SF5 ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED MAN(5)GLCNAC(2)-PP-DOLICHOL TRANSLOCATION PROTEIN RFT1 lipid localization#GO:0010876;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;lipid transport#GO:0006869;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid translocation#GO:0034204 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000005028.3|UniProtKB=G3QQQ4 G3QQQ4 DCPS PTHR12978:SF0 HISTIDINE TRIAD HIT PROTEIN MEMBER M7GPPPX DIPHOSPHATASE nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;RNA decapping#GO:0110154;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;nucleus#GO:0005634 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000009078.3|UniProtKB=G3RZ02 G3RZ02 EPCIP PTHR35658:SF1 RCG58666, ISOFORM CRA_A EXOSOMAL POLYCYSTIN-1-INTERACTING PROTEIN export from cell#GO:0140352;establishment of organelle localization#GO:0051656;cellular process#GO:0009987;mitochondrion localization#GO:0051646;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;organelle localization#GO:0051640 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000010081.4|UniProtKB=G3R3L8 G3R3L8 LRRIQ1 PTHR46652:SF11 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT- AND IQ DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000000997.3|UniProtKB=A0A2I2ZWS9 A0A2I2ZWS9 PCDH1 PTHR24028:SF247 CADHERIN-87A PROTOCADHERIN-1 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000016856.3|UniProtKB=A0A2I2Z5Q6 A0A2I2Z5Q6 ARHGAP33 PTHR15729:SF11 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 33 GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000006970.3|UniProtKB=A0A2I2YV06 A0A2I2YV06 EXOSC3 PTHR21321:SF1 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP40 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of 5.8S rRNA#GO:0000460;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;snRNA 3'-end processing#GO:0034472;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;snRNA processing#GO:0016180;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;snRNA metabolic process#GO:0016073 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000011227.3|UniProtKB=G3R6I7 G3R6I7 ZNF467 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003125.3|UniProtKB=G3QKT9 G3QKT9 CABP5 PTHR45917:SF3 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 5 transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 signal transduction#GO:0007165;response to radiation#GO:0009314;cellular process#GO:0009987;detection of stimulus#GO:0051606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to external stimulus#GO:0009605;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;sensory perception of light stimulus#GO:0050953;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;visual perception#GO:0007601;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154 GORGO|Ensembl=ENSGGOG00000038523.1|UniProtKB=A0A2I2YEL7 A0A2I2YEL7 ZNF596 PTHR24381:SF30 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 596 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001911.3|UniProtKB=G3RPH1 G3RPH1 NXF1 PTHR10662:SF27 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000028091.2|UniProtKB=G3RTN8 G3RTN8 TXN2 PTHR43601:SF39 THIOREDOXIN, MITOCHONDRIAL THIOREDOXIN, MITOCHONDRIAL cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 GORGO|Ensembl=ENSGGOG00000037786.1|UniProtKB=A0A2I2YPL8 A0A2I2YPL8 PTHR22426:SF6 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 SMALL ACIDIC PROTEIN-LIKE DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000023385.2|UniProtKB=A0A2I2Z3K5 A0A2I2Z3K5 RNF145 PTHR22763:SF167 RING ZINC FINGER PROTEIN RING FINGER PROTEIN 145 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012477.3|UniProtKB=G3R9T0 G3R9T0 METTL22 PTHR23108:SF0 METHYLTRANSFERASE-RELATED METHYLTRANSFERASE-LIKE PROTEIN 22 transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000039965.1|UniProtKB=A0A2I2YD99 A0A2I2YD99 CXCR1 PTHR10489:SF916 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 1 cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 calcium-mediated signaling#GO:0019722;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;leukocyte migration#GO:0050900;cell migration#GO:0016477;biological regulation#GO:0065007;immune response#GO:0006955;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;chemotaxis#GO:0006935;cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;neutrophil chemotaxis#GO:0030593;granulocyte migration#GO:0097530;response to chemical#GO:0042221;taxis#GO:0042330;neutrophil migration#GO:1990266;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological quality#GO:0065008;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854;Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000010176.4|UniProtKB=G3R3U6 G3R3U6 WDR25 PTHR44566:SF1 TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN WD REPEAT-CONTAINING PROTEIN 25 GORGO|Ensembl=ENSGGOG00000023270.2|UniProtKB=A0A2I2YXU5 A0A2I2YXU5 PTHR23158:SF53 MELANOMA INHIBITORY ACTIVITY-RELATED CTAGE FAMILY MEMBER 5 secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;protein secretion#GO:0009306;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;secretion by cell#GO:0032940;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000008674.3|UniProtKB=G3S009 G3S009 PPP1R37 PTHR24112:SF68 LEUCINE-RICH REPEAT, ISOFORM F-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37 cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000014613.3|UniProtKB=G3RF96 G3RF96 TFAP2B PTHR10812:SF14 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-BETA DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of apoptotic process#GO:0043066;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;regulation of apoptotic process#GO:0042981;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000004325.3|UniProtKB=G3SH09 G3SH09 SENP1 PTHR12606:SF30 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190 GORGO|Ensembl=ENSGGOG00000001210.3|UniProtKB=A0A2I2Z863 A0A2I2Z863 NCS1 PTHR23055:SF198 CALCIUM BINDING PROTEINS NEURONAL CALCIUM SENSOR 1 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;molecular function activator activity#GO:0140677;cation binding#GO:0043169;enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851;molecular function regulator activity#GO:0098772 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000028122.2|UniProtKB=G3S5H3 G3S5H3 AK3 PTHR23359:SF68 NUCLEOTIDE KINASE GTP:AMP PHOSPHOTRANSFERASE AK3, MITOCHONDRIAL phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 GORGO|Ensembl=ENSGGOG00000023712.2|UniProtKB=G3RWU3 G3RWU3 LOC101130789 PTHR31239:SF3 NICOLIN 1 NICN1 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000027331.2|UniProtKB=G3RVX1 G3RVX1 PTHR22834:SF17 NUCLEAR FUSION PROTEIN FUS2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 38 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000007437.3|UniProtKB=A0A2I2ZGR3 A0A2I2ZGR3 SRC PTHR24418:SF53 TYROSINE-PROTEIN KINASE PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715 regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;regulation of cell communication#GO:0010646;regulation of extrinsic apoptotic signaling pathway#GO:2001236;steroid hormone receptor signaling pathway#GO:0043401;regulation of intrinsic apoptotic signaling pathway#GO:2001242;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular signal transduction#GO:0035556;response to steroid hormone#GO:0048545;negative regulation of apoptotic signaling pathway#GO:2001234;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of apoptotic signaling pathway#GO:2001233;nuclear receptor-mediated signaling pathway#GO:0141193;negative regulation of apoptotic process#GO:0043066;epidermal growth factor receptor signaling pathway#GO:0007173;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;ERBB signaling pathway#GO:0038127;cellular developmental process#GO:0048869;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;hormone-mediated signaling pathway#GO:0009755;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;negative regulation of signal transduction#GO:0009968;response to hormone#GO:0009725;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;cellular response to steroid hormone stimulus#GO:0071383;cell surface receptor signaling pathway#GO:0007166;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of apoptotic process#GO:0042981 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Src#P00468;CCKR signaling map#P06959>p62 SRC#P07047;Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940;Angiogenesis#P00005>Src#P00184;CCKR signaling map#P06959>p54 SRC#P07109;CCKR signaling map#P06959>SRC#P07202;CCKR signaling map#P06959>SRC @Galphaq#P07163;Gonadotropin-releasing hormone receptor pathway#P06664>SRC#P06844;CCKR signaling map#P06959>p60 SRC#P07207 GORGO|Ensembl=ENSGGOG00000005603.3|UniProtKB=G3QS57 G3QS57 RIT2 PTHR24070:SF203 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RIT2 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;pyrophosphatase activity#GO:0016462;protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;GTPase activity#GO:0003924 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;positive regulation of neuron projection development#GO:0010976;Ras protein signal transduction#GO:0007265;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000038594.1|UniProtKB=A0A2I2YLD1 A0A2I2YLD1 PTHR11587:SF7 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000039677.1|UniProtKB=A0A2I2YDF9 A0A2I2YDF9 PTHR12403:SF25 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-LIKE PROTEIN vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006279.3|UniProtKB=Q0MQB9 Q0MQB9 NDUFA11 PTHR21382:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009818.3|UniProtKB=G3R2Y0 G3R2Y0 SLC43A3 PTHR20765:SF1 SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1 secondary carrier transporter#PC00258;amino acid transporter#PC00046 GORGO|Ensembl=ENSGGOG00000013139.3|UniProtKB=G3RMG3 G3RMG3 NCF4 PTHR15706:SF20 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 4 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;superoxide metabolic process#GO:0006801 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000802.3|UniProtKB=A0A2I2Y2B4 A0A2I2Y2B4 TYRO3 PTHR24416:SF279 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TYRO3 catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 hemostasis#GO:0007599;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell activation#GO:0001775;localization#GO:0051179;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;response to wounding#GO:0009611;multicellular organismal process#GO:0032501;cell migration#GO:0016477;biological regulation#GO:0065007;homotypic cell-cell adhesion#GO:0034109;phagocytosis#GO:0006909;developmental process#GO:0032502;transport#GO:0006810;platelet activation#GO:0030168;establishment of localization#GO:0051234;blood coagulation#GO:0007596;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;endocytosis#GO:0006897;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;wound healing#GO:0042060;regulation of biological quality#GO:0065008;cell-cell adhesion#GO:0098609;response to stress#GO:0006950;signal transduction#GO:0007165;coagulation#GO:0050817;cellular process#GO:0009987;nervous system development#GO:0007399;platelet aggregation#GO:0070527;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;import into cell#GO:0098657 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000372.3|UniProtKB=G3RUR6 G3RUR6 VPS39 PTHR12894:SF49 CNH DOMAIN CONTAINING VAM6_VPS39-LIKE PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;small GTPase binding#GO:0031267;protein binding#GO:0005515 vacuole fusion#GO:0097576;cellular component disassembly#GO:0022411;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization#GO:0016043;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular process#GO:0009987;autophagy#GO:0006914;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;macroautophagy#GO:0016236 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vesicle tethering complex#GO:0099023;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000000603.3|UniProtKB=A0A2I2YL51 A0A2I2YL51 WDR18 PTHR18763:SF0 WD-REPEAT PROTEIN 18 WD REPEAT-CONTAINING PROTEIN 18 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nuclear pre-replicative complex#GO:0005656;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoribonuclease complex#GO:1902555;intracellular organelle lumen#GO:0070013;pre-replicative complex#GO:0036387;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002278.3|UniProtKB=G3QIM7 G3QIM7 PDIA6 PTHR45815:SF3 PROTEIN DISULFIDE-ISOMERASE A6 PROTEIN DISULFIDE-ISOMERASE A6 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000043344.1|UniProtKB=A0A2I2YM18 A0A2I2YM18 PTHR12905:SF31 METALLOPHOSPHOESTERASE METALLOPHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 GORGO|Ensembl=ENSGGOG00000007993.3|UniProtKB=G3QY87 G3QY87 HBM PTHR11442:SF8 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT MU heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488;tetrapyrrole binding#GO:0046906 cellular process#GO:0009987;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;cell development#GO:0048468;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;localization#GO:0051179;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 globin#PC00107;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000002358.3|UniProtKB=A0A2I2YNY1 A0A2I2YNY1 API5 PTHR12758:SF23 APOPTOSIS INHIBITOR 5-RELATED APOPTOSIS INHIBITOR 5 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000002179.3|UniProtKB=A0A2I2ZMN3 A0A2I2ZMN3 ITPRID2 PTHR17469:SF11 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN ITPRID2 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005159.3|UniProtKB=G3QR20 G3QR20 IL31 PTHR38652:SF1 INTERLEUKIN-31 INTERLEUKIN-31 binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 interleukin superfamily#PC00128;cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000010133.3|UniProtKB=G3S6S9 G3S6S9 PTHR32005:SF4 TRANSMEMBRANE PROTEIN 178B-RELATED TRANSMEMBRANE PROTEIN 178A regulation of hemopoiesis#GO:1903706;inorganic ion homeostasis#GO:0098771;regulation of myeloid cell differentiation#GO:0045637;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;regulation of developmental process#GO:0050793;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of cytosolic calcium ion concentration#GO:0051480;negative regulation of biological process#GO:0048519;intracellular monoatomic ion homeostasis#GO:0006873;negative regulation of multicellular organismal process#GO:0051241;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;regulation of cell differentiation#GO:0045595;intracellular monoatomic cation homeostasis#GO:0030003;negative regulation of cellular process#GO:0048523;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;monoatomic ion homeostasis#GO:0050801 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000011457.3|UniProtKB=G3R749 G3R749 CDC25B PTHR10828:SF48 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 M-PHASE INDUCER PHOSPHATASE 2 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of cell cycle#GO:0051726;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of meiotic cell cycle#GO:0051445;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic cell cycle phase transition#GO:0044772;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of reproductive process#GO:2000241;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cell cycle G2/M phase transition#GO:0044839;positive regulation of cellular process#GO:0048522;regulation of cell cycle G2/M phase transition#GO:1902749;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011042.3|UniProtKB=G3R629 G3R629 ITIH6 PTHR10338:SF155 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H6 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000014974.3|UniProtKB=G3RG70 G3RG70 RHOD PTHR24072:SF175 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOD nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899 supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029;signaling#GO:0023052;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cell migration#GO:0016477;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000004176.3|UniProtKB=G3QNH8 G3QNH8 PXT1 PTHR40381:SF1 PEROXISOMAL TESTIS-SPECIFIC PROTEIN 1 PEROXISOMAL TESTIS-SPECIFIC PROTEIN 1 GORGO|Ensembl=ENSGGOG00000027162.2|UniProtKB=A0A2I2ZII6 A0A2I2ZII6 PTHR24020:SF23 COLLAGEN ALPHA VITRIN cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;extracellular structure organization#GO:0043062;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;interstitial matrix#GO:0005614 extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000022308.2|UniProtKB=A0A2I2YSV9 A0A2I2YSV9 PTHR13194:SF25 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000006626.3|UniProtKB=G3QUS8 G3QUS8 PDZD11 PTHR14063:SF1 PROTEIN LIN-7 HOMOLOG PDZ DOMAIN-CONTAINING PROTEIN 11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component biogenesis#GO:0044085;synaptic vesicle transport#GO:0048489;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;synaptic vesicle localization#GO:0097479;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component biogenesis#GO:0044087;regulation of synapse organization#GO:0050807;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of biological quality#GO:0065008;vesicle localization#GO:0051648;regulation of synapse assembly#GO:0051963;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;transport#GO:0006810;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of growth#GO:0040008;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;regulation of cell junction assembly#GO:1901888;localization#GO:0051179;cell communication#GO:0007154;regulation of synapse structure or activity#GO:0050803;secretion#GO:0046903 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;cell-cell junction#GO:0005911;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000010943.3|UniProtKB=G3R5W5 G3R5W5 PKHD1 PTHR46769:SF1 POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1 FIBROCYSTIN GORGO|Ensembl=ENSGGOG00000003983.3|UniProtKB=G3S7Z4 G3S7Z4 RXRG PTHR24083:SF100 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-GAMMA transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;positive regulation of RNA metabolic process#GO:0051254;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;hormone-mediated signaling pathway#GO:0009755;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000025569.2|UniProtKB=A0A2I2YFK9 A0A2I2YFK9 CNN1 PTHR46756:SF1 TRANSGELIN CALPONIN-1 binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;supramolecular fiber organization#GO:0097435;regulation of microtubule-based process#GO:0032886;actin filament-based process#GO:0030029;microtubule bundle formation#GO:0001578;protein localization to microtubule cytoskeleton#GO:0072698;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;actin filament organization#GO:0007015;intracellular protein localization#GO:0008104 microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;stress fiber#GO:0001725;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;actomyosin#GO:0042641;microtubule#GO:0005874;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;microtubule end#GO:1990752 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000041620.1|UniProtKB=A0A2I2ZJQ3 A0A2I2ZJQ3 PTHR10800:SF7 PULMONARY SURFACTANT-ASSOCIATED PROTEIN C SURFACTANT PROTEIN C vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227 surfactant#PC00212;structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000006907.3|UniProtKB=A0A2I2ZG78 A0A2I2ZG78 LGALS8 PTHR11346:SF22 GALECTIN GALECTIN-8 carbohydrate binding#GO:0030246;binding#GO:0005488 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000006976.3|UniProtKB=A0A2I2YZS3 A0A2I2YZS3 RASGRF2 PTHR23113:SF187 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 2 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000007197.3|UniProtKB=G3QW90 G3QW90 AURKA PTHR24350:SF5 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE A protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000010019.3|UniProtKB=G3R3F1 G3R3F1 GPR152 PTHR11334:SF1 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 152-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000008403.3|UniProtKB=G3S788 G3S788 PPFIA3 PTHR12587:SF4 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-3 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043 presynaptic active zone#GO:0048786;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003699.3|UniProtKB=G3SB19 G3SB19 CAPNS1 PTHR46735:SF1 CALPAIN, SMALL SUBUNIT 1 A-RELATED CALPAIN SMALL SUBUNIT 1 intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;caspase complex#GO:0008303;cytoplasm#GO:0005737;peptidase complex#GO:1905368 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000014548.3|UniProtKB=A0A2I2ZSJ1 A0A2I2ZSJ1 C15H14orf93 PTHR14375:SF2 SIMILAR TO RIKEN CDNA 4931414P19 SIMILAR TO HUMAN CHROMOSOME 14 OPEN READING FRAME 93 GORGO|Ensembl=ENSGGOG00000040911.1|UniProtKB=A0A2I2ZQJ3 A0A2I2ZQJ3 GJC1 PTHR11984:SF6 CONNEXIN GAP JUNCTION GAMMA-1 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;cell junction#GO:0030054 cell junction protein#PC00070;gap junction#PC00105 GORGO|Ensembl=ENSGGOG00000015904.3|UniProtKB=G3RIK4 G3RIK4 METTL18 PTHR14614:SF177 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007864.3|UniProtKB=G3RV65 G3RV65 IRAG1 PTHR15352:SF2 LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1 INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 1 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015820.3|UniProtKB=G3RIC8 G3RIC8 CHST12 PTHR12137:SF4 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 12 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000006323.3|UniProtKB=G3QU00 G3QU00 ECM1 PTHR16776:SF3 EXTRACELLULAR MATRIX PROTEIN 1 EXTRACELLULAR MATRIX PROTEIN 1 regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;regulation of bone mineralization#GO:0030500;biological regulation#GO:0065007;regulation of developmental process#GO:0050793 GORGO|Ensembl=ENSGGOG00000002077.3|UniProtKB=G3QI45 G3QI45 PTTG1IP PTHR15191:SF14 PROTEIN CBG20567 PITUITARY TUMOR-TRANSFORMING GENE 1 PROTEIN-INTERACTING PROTEIN import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000042558.1|UniProtKB=A0A2I2YUG2 A0A2I2YUG2 PTHR23232:SF178 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN 5-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000037859.1|UniProtKB=A0A2I2YL23 A0A2I2YL23 PTHR25952:SF259 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN AC1233 GORGO|Ensembl=ENSGGOG00000003287.4|UniProtKB=A0A2I2Z8S9 A0A2I2Z8S9 ABCB11 PTHR24221:SF165 ATP-BINDING CASSETTE SUB-FAMILY B BILE SALT EXPORT PUMP primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000008144.3|UniProtKB=G3QYM0 G3QYM0 BCL9L PTHR15185:SF3 BCL9 B-CELL CLL_LYMPHOMA 9-LIKE PROTEIN binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;cellular response to stimulus#GO:0051716;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000024611.2|UniProtKB=A0A2I2Y1R8 A0A2I2Y1R8 EFR3A PTHR12444:SF1 PROTEIN EFR3 HOMOLOG CMP44E PROTEIN EFR3 HOMOLOG A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000009616.3|UniProtKB=G3R2F1 G3R2F1 MED13 PTHR48249:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000025495.2|UniProtKB=G3S9F1 G3S9F1 ACTL7A PTHR11937:SF167 ACTIN ACTIN-LIKE PROTEIN 7A structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000005611.3|UniProtKB=A0A2I2ZXY2 A0A2I2ZXY2 SPRYD7 PTHR20951:SF2 C13ORF1 PROTEIN-RELATED SPRY DOMAIN-CONTAINING PROTEIN 7 GORGO|Ensembl=ENSGGOG00000027463.2|UniProtKB=G3SA93 G3SA93 SOX15 PTHR10270:SF45 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-15 sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;head development#GO:0060322;nervous system development#GO:0007399 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000005117.3|UniProtKB=G3SJE7 G3SJE7 NPC1 PTHR45727:SF11 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934;alcohol binding#GO:0043178;cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496 establishment of localization#GO:0051234;sterol transport#GO:0015918;cholesterol homeostasis#GO:0042632;localization#GO:0051179;system process#GO:0003008;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;transport#GO:0006810;chemical homeostasis#GO:0048878;multicellular organismal process#GO:0032501;digestion#GO:0007586;lipid transport#GO:0006869;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;macromolecule localization#GO:0033036 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000015849.3|UniProtKB=A0A2I2Y5T2 A0A2I2Y5T2 PTHR13308:SF5 NEDD4-BINDING PROTEIN 2-LIKE 1 NEDD4-BINDING PROTEIN 2-LIKE 1 GORGO|Ensembl=ENSGGOG00000001942.3|UniProtKB=A0A2I2ZNC2 A0A2I2ZNC2 PDLIM3 PTHR24214:SF7 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 3 protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;heart development#GO:0007507;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;actomyosin#GO:0042641;Z disc#GO:0030018;cell-cell junction#GO:0005911;adherens junction#GO:0005912;cell junction#GO:0030054;sarcomere#GO:0030017;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;I band#GO:0031674;actin filament#GO:0005884;cytoskeleton#GO:0005856;stress fiber#GO:0001725 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000005897.3|UniProtKB=G3QSX4 G3QSX4 AQP2 PTHR19139:SF45 AQUAPORIN TRANSPORTER AQUAPORIN-2 channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372 transport#GO:0006810;fluid transport#GO:0042044;water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001223.3|UniProtKB=G3QFX1 G3QFX1 LOC101134144 PTHR10816:SF9 MYELIN TRANSCRIPTION FACTOR 1-RELATED SUPPRESSION OF TUMORIGENICITY 18 PROTEIN DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000037409.1|UniProtKB=A0A2I2ZMW0 A0A2I2ZMW0 FUT9 PTHR11929:SF10 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE 9 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000014187.3|UniProtKB=G3RE73 G3RE73 ATP2B1 PTHR24093:SF245 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 1 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 regulation of cytosolic calcium ion concentration#GO:0051480;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;calcium ion homeostasis#GO:0055074;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000012368.3|UniProtKB=G3R9I2 G3R9I2 PIPOX PTHR10961:SF46 PEROXISOMAL SARCOSINE OXIDASE PEROXISOMAL SARCOSINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579 metabolite interconversion enzyme#PC00262;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000010722.3|UniProtKB=A0A2I2YBK9 A0A2I2YBK9 RAP1GAP PTHR15711:SF3 RAP GTPASE-ACTIVATING PROTEIN RAP1 GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of cell adhesion#GO:0030155 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424 G-protein modulator#PC00022;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1GAP#P00737 GORGO|Ensembl=ENSGGOG00000014248.3|UniProtKB=G3REC1 G3REC1 CLK4 PTHR45646:SF1 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK4 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000003696.3|UniProtKB=G3QMA0 G3QMA0 OSGIN2 PTHR15192:SF4 PROTEIN CBG05349 OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 2 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545 regulation of growth#GO:0040008;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell growth#GO:0030308;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell growth#GO:0001558;regulation of cellular component organization#GO:0051128;negative regulation of cellular process#GO:0048523 GORGO|Ensembl=ENSGGOG00000005123.3|UniProtKB=A0A2I2YF64 A0A2I2YF64 ANKRD29 PTHR24120:SF3 GH07239P ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 29 GORGO|Ensembl=ENSGGOG00000008851.3|UniProtKB=G3R0H0 G3R0H0 ST8SIA6 PTHR11987:SF29 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8F sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000039847.1|UniProtKB=A0A2I2ZGJ8 A0A2I2ZGJ8 PTHR11587:SF8 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000004558.3|UniProtKB=G3QPH6 G3QPH6 TRPC3 PTHR10117:SF8 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 3 channel activity#GO:0015267;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;single fertilization#GO:0007338;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;homeostatic process#GO:0042592;metal ion transport#GO:0030001;fertilization#GO:0009566;reproductive process#GO:0022414;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;sexual reproduction#GO:0019953;inorganic ion homeostasis#GO:0098771 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 GORGO|Gene=RNASE6|UniProtKB=O46532 O46532 RNASE6 PTHR11437:SF4 RIBONUCLEASE RIBONUCLEASE K6 catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to Gram-negative bacterium#GO:0050829;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004887.3|UniProtKB=G3QQC5 G3QQC5 RAD51AP2 PTHR39229:SF1 MCG1037962 RAD51-ASSOCIATED PROTEIN 2 GORGO|Ensembl=ENSGGOG00000042283.1|UniProtKB=A0A2I2ZA81 A0A2I2ZA81 PTHR24300:SF406 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2B6 heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;olefinic compound metabolic process#GO:0120254;response to xenobiotic stimulus#GO:0009410;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;xenobiotic metabolic process#GO:0006805;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxygenase#PC00177;oxidoreductase#PC00176 Bupropion degradation#P05729>Cytochrome P450 2B6#P05742 GORGO|Ensembl=ENSGGOG00000007515.3|UniProtKB=G3QX24 G3QX24 CFAP97 PTHR23035:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97 GORGO|Ensembl=ENSGGOG00000008659.3|UniProtKB=G3QZZ3 G3QZZ3 GNAT1 PTHR10218:SF67 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;visual perception#GO:0007601;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;signaling#GO:0023052;sensory perception of light stimulus#GO:0050953;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;cellular process#GO:0009987;response to radiation#GO:0009314;signal transduction#GO:0007165;system process#GO:0003008;response to external stimulus#GO:0009605;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;side of membrane#GO:0098552;catalytic complex#GO:1902494;cilium#GO:0005929;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117;G-protein#PC00020 Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid proenkephalin pathway#P05915>G-protein#P05994;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;PI3 kinase pathway#P00048>Galpha#P01199;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gtalpha#P00760;Enkephalin release#P05913>G-Protein (i)#P05974 GORGO|Ensembl=ENSGGOG00000000878.3|UniProtKB=G3QF07 G3QF07 HEATR3 PTHR13347:SF1 HEAT REPEAT-CONTAINING PROTEIN 3 HEAT REPEAT-CONTAINING PROTEIN 3 cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to organelle#GO:0033365;ribonucleoprotein complex biogenesis#GO:0022613;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleocytoplasmic transport#GO:0006913 GORGO|Ensembl=ENSGGOG00000011581.3|UniProtKB=G3RWE7 G3RWE7 IL5 PTHR48491:SF1 INTERLEUKIN-5 INTERLEUKIN-5 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;signaling#GO:0023052;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Interleukin signaling pathway#P00036>Interleukin#P00970;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 GORGO|Ensembl=ENSGGOG00000042185.1|UniProtKB=A0A2I2YW45 A0A2I2YW45 PTHR24264:SF62 TRYPSIN-RELATED TRYPSIN peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000027182.2|UniProtKB=G3RR85 G3RR85 SH3BGRL2 PTHR12232:SF4 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000002546.4|UniProtKB=G3QJB7 G3QJB7 CNNM1 PTHR12064:SF28 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003798.3|UniProtKB=G3QMJ2 G3QMJ2 PTHR12369:SF46 CHONDROITIN SYNTHASE N-ACETYL-BETA-GLUCOSAMINYL-GLYCOPROTEIN 4-BETA-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000043203.1|UniProtKB=A0A2I2YWL9 A0A2I2YWL9 PTHR23415:SF42 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 1 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015485.3|UniProtKB=G3RHI6 G3RHI6 DHRS7C PTHR44668:SF2 FAMILY NOT NAMED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7C GORGO|Ensembl=ENSGGOG00000004831.3|UniProtKB=G3QQ71 G3QQ71 MIS18A PTHR16431:SF2 NEUROGENIC PROTEIN MASTERMIND PROTEIN MIS18-ALPHA cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;kinetochore organization#GO:0051383;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000257.3|UniProtKB=G3QDE0 G3QDE0 CLECL1P PTHR46746:SF3 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY F MEMBER 2 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040656.1|UniProtKB=A0A2I2ZTZ2 A0A2I2ZTZ2 IGHV5-51 PTHR23266:SF348 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 5-10-1-RELATED binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000024620.2|UniProtKB=G3RSH0 G3RSH0 LOC109023730 PTHR10969:SF15 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 BETA-RELATED phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;microtubule binding#GO:0008017;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289 cellular response to stress#GO:0033554;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to nutrient levels#GO:0031669;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000014238.3|UniProtKB=G3REA8 G3REA8 PTHR10091:SF0 ALDOSE-1-EPIMERASE GALACTOSE MUTAROTASE catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 epimerase/racemase#PC00096 GORGO|Ensembl=ENSGGOG00000004007.3|UniProtKB=G3QN32 G3QN32 LOC101149786 PTHR24044:SF471 NOTCH LIGAND FAMILY MEMBER NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Notch signaling pathway#GO:0045746;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;negative regulation of cellular process#GO:0048523;Notch signaling pathway#GO:0007219 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000022826.2|UniProtKB=Q6YK33 Q6YK33 INS PTHR11454:SF34 INSULIN/INSULIN GROWTH FACTOR INSULIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 regulation of biological process#GO:0050789;carbohydrate homeostasis#GO:0033500;regulation of protein secretion#GO:0050708;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;positive regulation of secretion#GO:0051047;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;biological regulation#GO:0065007;chemical homeostasis#GO:0048878;regulation of transport#GO:0051049;glucose homeostasis#GO:0042593;regulation of localization#GO:0032879;positive regulation of protein secretion#GO:0050714 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Gonadotropin-releasing hormone receptor pathway#P06664>Insulin#P06793 GORGO|Ensembl=ENSGGOG00000015738.3|UniProtKB=G3RI64 G3RI64 CTBS PTHR46290:SF8 DI-N-ACETYLCHITOBIASE DI-N-ACETYLCHITOBIASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 carbohydrate catabolic process#GO:0016052;aminoglycan metabolic process#GO:0006022;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000007255.3|UniProtKB=A0A2I2YYR1 A0A2I2YYR1 PCSK2 PTHR42884:SF13 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 2 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 proteolysis#GO:0006508;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;peptide hormone processing#GO:0016486;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;biological regulation#GO:0065007 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 GORGO|Ensembl=ENSGGOG00000022333.2|UniProtKB=G3SFT9 G3SFT9 ANO8 PTHR12308:SF51 ANOCTAMIN ANOCTAMIN-8 phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303 macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000043831.1|UniProtKB=A0A2I2Y2H5 A0A2I2Y2H5 PTHR11902:SF38 ENOLASE PHOSPHOPYRUVATE HYDRATASE phosphopyruvate hydratase activity#GO:0004634;catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117 catalytic complex#GO:1902494;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000014851.3|UniProtKB=G3RFX2 G3RFX2 ABCA5 PTHR19229:SF100 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA CHOLESTEROL TRANSPORTER ABCA5 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179;transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000006872.3|UniProtKB=G3QVG0 G3QVG0 BSG PTHR10075:SF107 BASIGIN RELATED BASIGIN cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000009714.3|UniProtKB=G3R2N2 G3R2N2 KIN PTHR12805:SF0 KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG DNA_RNA-BINDING PROTEIN KIN17 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676 response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000014585.3|UniProtKB=G3RF67 G3RF67 SLC22A15 PTHR24064:SF170 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 15 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000041459.1|UniProtKB=A0A2I2Z1S7 A0A2I2Z1S7 PTHR12297:SF5 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A, MITOCHONDRIAL cellular component assembly#GO:0022607;negative regulation of apoptotic process#GO:0043066;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Gene=NDUFA8|UniProtKB=Q0MQB0 Q0MQB0 NDUFA8 PTHR13344:SF0 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016477.3|UniProtKB=A0A2I2YA82 A0A2I2YA82 SPMIP4 PTHR31393:SF2 C5ORF31 SPERM-ASSOCIATED MICROTUBULE INNER PROTEIN 4 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000007420.3|UniProtKB=A0A2I2ZEF2 A0A2I2ZEF2 MFSD10 PTHR23504:SF121 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 75 MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cluster of actin-based cell projections#GO:0098862;cell projection membrane#GO:0031253;apical part of cell#GO:0045177;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;brush border membrane#GO:0031526;plasma membrane region#GO:0098590;cell periphery#GO:0071944;brush border#GO:0005903;membrane#GO:0016020;apical plasma membrane#GO:0016324 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000013593.3|UniProtKB=A0A2I2Z2M6 A0A2I2Z2M6 NXT2 PTHR12612:SF1 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 2 macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006441.3|UniProtKB=A0A2I2Z882 A0A2I2Z882 SDAD1 PTHR12730:SF1 HSDA/SDA1-RELATED PROTEIN SDA1 HOMOLOG ribosomal large subunit export from nucleus#GO:0000055;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;ribosomal large subunit biogenesis#GO:0042273;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;transport#GO:0006810;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000009439.4|UniProtKB=G3R1Y7 G3R1Y7 BBOX1 PTHR10696:SF33 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED GAMMA-BUTYROBETAINE DIOXYGENASE oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 carnitine metabolic process#GO:0009437;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;hydroxylase#PC00122 GORGO|Ensembl=ENSGGOG00000000545.3|UniProtKB=G3QE50 G3QE50 LATS1 PTHR24356:SF138 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE LATS1 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 mitotic cell cycle phase transition#GO:0044772;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of programmed cell death#GO:0043067;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;signaling#GO:0023052;G1/S transition of mitotic cell cycle#GO:0000082;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;mitotic cell cycle process#GO:1903047;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;hippo signaling#GO:0035329;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000010263.3|UniProtKB=A0A2I2ZN06 A0A2I2ZN06 ESRRG PTHR48092:SF10 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN-RELATED RECEPTOR GAMMA double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000010797.3|UniProtKB=G3R5F3 G3R5F3 PNPLA2 PTHR12406:SF29 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;triacylglycerol lipase activity#GO:0004806;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 neutral lipid metabolic process#GO:0006638;cellular component organization or biogenesis#GO:0071840;acylglycerol catabolic process#GO:0046464;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid catabolic process#GO:0046461;triglyceride metabolic process#GO:0006641;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;organelle organization#GO:0006996;lipid catabolic process#GO:0016042;cellular process#GO:0009987;triglyceride catabolic process#GO:0019433;lipid droplet organization#GO:0034389;glycerolipid catabolic process#GO:0046503;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000027601.2|UniProtKB=G3SDK0 G3SDK0 AMELY PTHR46794:SF2 AMELOGENIN, Y ISOFORM AMELOGENIN, X ISOFORM extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 animal organ development#GO:0048513;anatomical structure development#GO:0048856;anatomical structure formation involved in morphogenesis#GO:0048646;animal gross anatomical part developmental process#GO:0160108;enamel mineralization#GO:0070166;biomineral tissue development#GO:0031214;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;tissue development#GO:0009888;odontogenesis of dentin-containing tooth#GO:0042475;odontogenesis#GO:0042476;amelogenesis#GO:0097186;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 GORGO|Ensembl=ENSGGOG00000013083.3|UniProtKB=A0A2I2ZPU5 A0A2I2ZPU5 IQCA1 PTHR14690:SF8 IQ MOTIF CONTAINING WITH AAA DOMAIN 1 DYNEIN REGULATORY COMPLEX SUBUNIT 11 GORGO|Ensembl=ENSGGOG00000022727.2|UniProtKB=G3S5X5 G3S5X5 PTHR31859:SF5 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT DOMAIN 39D negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of metabolic process#GO:0019222;lipid homeostasis#GO:0055088;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000001368.3|UniProtKB=A0A2I2ZGC8 A0A2I2ZGC8 UBE2D2 PTHR24068:SF330 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D2 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000011137.3|UniProtKB=G3R6B0 G3R6B0 ZNF177 PTHR24381:SF403 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 177 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000010915.3|UniProtKB=A0A2I2YRC6 A0A2I2YRC6 DNAJB2 PTHR45168:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 2 DNAJ HOMOLOG SUBFAMILY B MEMBER 2 Hsp70 protein binding#GO:0030544;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein refolding#GO:0042026;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000043025.1|UniProtKB=A0A2I2Y5C1 A0A2I2Y5C1 PTHR10369:SF45 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN EL42-LIKE structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000028062.2|UniProtKB=G3RLK9 G3RLK9 PTHR11961:SF31 CYTOCHROME C CYTOCHROME C metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002341.3|UniProtKB=G3QIT7 G3QIT7 EFNA2 PTHR11304:SF4 EPHRIN EPHRIN-A2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;hemopoiesis#GO:0030097;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;osteoclast differentiation#GO:0030316;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;myeloid cell differentiation#GO:0030099;cell morphogenesis#GO:0000902;bone remodeling#GO:0046849;signaling#GO:0023052;tissue remodeling#GO:0048771;cell development#GO:0048468;cellular component organization#GO:0016043;leukocyte differentiation#GO:0002521;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000016318.3|UniProtKB=G3RJM1 G3RJM1 FCF1 PTHR12416:SF8 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN FCF1 HOMOLOG nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 GORGO|Ensembl=ENSGGOG00000003022.3|UniProtKB=G3QKJ5 G3QKJ5 LOC101137794 PTHR26452:SF814 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000011413.3|UniProtKB=G3S523 G3S523 BCO2 PTHR10543:SF122 BETA-CAROTENE DIOXYGENASE CAROTENOID-CLEAVING DIOXYGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 metabolic process#GO:0008152;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;isoprenoid metabolic process#GO:0006720;diterpenoid metabolic process#GO:0016101;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;catabolic process#GO:0009056 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000002275.3|UniProtKB=G3RQL0 G3RQL0 ABCC2 PTHR24223:SF176 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 2 xenobiotic transmembrane transporter activity#GO:0042910;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000023450.2|UniProtKB=G3RR71 G3RR71 ME1 PTHR23406:SF17 MALIC ENZYME-RELATED NADP-DEPENDENT MALIC ENZYME oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Pyruvate metabolism#P02772>Malic enzyme#P03136 GORGO|Ensembl=ENSGGOG00000000899.3|UniProtKB=G3QF26 G3QF26 CFAP43 PTHR14885:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43 sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000023796.2|UniProtKB=A0A2I2ZXN3 A0A2I2ZXN3 IDH3G PTHR11835:SF78 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT GAMMA, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009432.3|UniProtKB=G3SG04 G3SG04 SCAMP3 PTHR10687:SF6 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 3 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506 transfer/carrier protein#PC00219 GORGO|Gene=RPS4Y1|UniProtKB=Q861U8 Q861U8 RPS4Y1 PTHR11581:SF8 30S/40S RIBOSOMAL PROTEIN S4 SMALL RIBOSOMAL SUBUNIT PROTEIN ES4, Y ISOFORM 1 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003010.3|UniProtKB=A0A2I2Z1V1 A0A2I2Z1V1 PHKB PTHR10749:SF8 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 GORGO|Ensembl=ENSGGOG00000002613.3|UniProtKB=G3QJH6 G3QJH6 CDCA3 PTHR34756:SF1 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3 GORGO|Ensembl=ENSGGOG00000006176.3|UniProtKB=G3RW37 G3RW37 LOC101146782 PTHR12670:SF21 CERAMIDASE NEUTRAL CERAMIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid catabolic process#GO:0016042;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;alcohol metabolic process#GO:0006066;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;ceramide metabolic process#GO:0006672;sphingoid biosynthetic process#GO:0046520 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016078.3|UniProtKB=G3SD43 G3SD43 ACAP2 PTHR23180:SF241 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000024219.2|UniProtKB=G3S163 G3S163 ELOVL3 PTHR11157:SF68 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 3 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000024994.2|UniProtKB=G3S6W7 G3S6W7 LOC101131259 PTHR12021:SF20 THYMOSIN BETA THYMOSIN BETA-4 protein binding#GO:0005515;molecular sequestering activity#GO:0140313;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein sequestering activity#GO:0140311;actin binding#GO:0003779;actin monomer binding#GO:0003785 regulation of cell migration#GO:0030334;regulation of biological process#GO:0050789;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell motility#GO:2000145 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000003047.3|UniProtKB=A0A2I2ZXW1 A0A2I2ZXW1 SLC35F2 PTHR14233:SF12 DUF914-RELATED QUEUINE_QUEUOSINE TRANSPORTER SLC35F2 GORGO|Ensembl=ENSGGOG00000009386.3|UniProtKB=G3R1U0 G3R1U0 FBXO31 PTHR10706:SF161 F-BOX FAMILY PROTEIN F-BOX ONLY PROTEIN 31 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000004949.3|UniProtKB=G3S409 G3S409 ATP1A2 PTHR43294:SF6 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;localization#GO:0051179;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;export from cell#GO:0140352;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000011182.3|UniProtKB=G3R6F3 G3R6F3 NR4A2 PTHR24085:SF0 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 2 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837 cellular response to endogenous stimulus#GO:0071495;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;generation of neurons#GO:0048699;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;cellular response to peptide hormone stimulus#GO:0071375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000038123.1|UniProtKB=A0A2I2YHT9 A0A2I2YHT9 PTHR23238:SF28 RNA BINDING PROTEIN EWS RNA BINDING PROTEIN 1 transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008852.3|UniProtKB=G3R0H2 G3R0H2 RETSAT PTHR46091:SF1 BLR7054 PROTEIN ALL-TRANS-RETINOL 13,14-REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 biological regulation#GO:0065007;hormone metabolic process#GO:0042445;cellular process#GO:0009987;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule metabolic process#GO:0044281;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000006678.3|UniProtKB=G3QUX6 G3QUX6 PTHR18952:SF89 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 5A, MITOCHONDRIAL hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000009815.3|UniProtKB=G3SJ41 G3SJ41 ABCD3 PTHR11384:SF62 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 3 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;nucleotide binding#GO:0000166;monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265 establishment of localization in cell#GO:0051649;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;fatty acid oxidation#GO:0019395;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;metabolic process#GO:0008152;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;cellular component organization#GO:0016043;carboxylic acid metabolic process#GO:0019752;fatty acid catabolic process#GO:0009062;cellular localization#GO:0051641;transmembrane transport#GO:0055085;peroxisome organization#GO:0007031;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;lipid transport#GO:0006869;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;macromolecule localization#GO:0033036;lipid modification#GO:0030258;establishment of localization#GO:0051234;fatty acid beta-oxidation#GO:0006635;transport#GO:0006810;lipid metabolic process#GO:0006629;intracellular transport#GO:0046907;fatty acid metabolic process#GO:0006631;carboxylic acid transmembrane transport#GO:1905039;catabolic process#GO:0009056;primary metabolic process#GO:0044238;peroxisomal transport#GO:0043574;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;lipid oxidation#GO:0034440 membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000014579.3|UniProtKB=G3RF64 G3RF64 ANKRD23 PTHR24126:SF45 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 23 DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000004643.3|UniProtKB=G3RWI5 G3RWI5 TMEM30B PTHR10926:SF19 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50B enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000001224.3|UniProtKB=G3QFX3 G3QFX3 POGLUT1 PTHR12203:SF126 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-xylosyltransferase activity#GO:0035252;UDP-glucosyltransferase activity#GO:0035251;xylosyltransferase activity#GO:0042285;glucosyltransferase activity#GO:0046527;pentosyltransferase activity#GO:0016763 cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of Notch signaling pathway#GO:0045747;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000036744.1|UniProtKB=A0A2I2ZUE8 A0A2I2ZUE8 PTHR11960:SF39 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000039258.1|UniProtKB=A0A2I2Z0M6 A0A2I2Z0M6 OTULIN PTHR33662:SF2 OTU DEUBIQUITINASE WITH LINEAR LINKAGE-SPECIFICITY A-RELATED UBIQUITIN THIOESTERASE OTULIN cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 protein modification by small protein conjugation or removal#GO:0070647;regulation of signaling#GO:0023051;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;regulation of cell communication#GO:0010646;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of response to cytokine stimulus#GO:0060759;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;post-translational protein modification#GO:0043687;regulation of signal transduction#GO:0009966;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009950.3|UniProtKB=A0A2I2ZS21 A0A2I2ZS21 RASGRF1 PTHR23113:SF193 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of synaptic plasticity#GO:0048167;regulation of trans-synaptic signaling#GO:0099177;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;Ras protein signal transduction#GO:0007265;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000041276.1|UniProtKB=G3RET3 G3RET3 LOC101136504 PTHR24381:SF404 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 736 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000016064.3|UniProtKB=G3RIZ9 G3RIZ9 HSD3B7 PTHR10366:SF847 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 7 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 lyase#PC00144;dehydratase#PC00091;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>3beta-hydroxy-Delta5-steroid dehydrogenase#P02837 GORGO|Ensembl=ENSGGOG00000013219.3|UniProtKB=G3RBN3 G3RBN3 PTHR12322:SF117 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR C1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;reproductive process#GO:0022414;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;sex differentiation#GO:0007548;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007573.3|UniProtKB=A0A2I2ZM84 A0A2I2ZM84 SUMF2 PTHR23150:SF33 SULFATASE MODIFYING FACTOR 1, 2 INACTIVE C-ALPHA-FORMYLGLYCINE-GENERATING ENZYME 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000026603.2|UniProtKB=A0A2I2YRY8 A0A2I2YRY8 RAB1A PTHR24073:SF963 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1A hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;organelle assembly#GO:0070925;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cell body#GO:0044297 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000025426.2|UniProtKB=G3S4M3 G3S4M3 GPR68 PTHR24234:SF5 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G PROTEIN-COUPLED RECEPTOR 68 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to abiotic stimulus#GO:0009628;cellular response to abiotic stimulus#GO:0071214;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016485.3|UniProtKB=G3RK26 G3RK26 PLIN2 PTHR14024:SF25 PERILIPIN PERILIPIN-2 positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;lipid storage#GO:0019915;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of localization#GO:0032879 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006964.3|UniProtKB=G3QVN0 G3QVN0 ZNF572 PTHR23226:SF335 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 572 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001552.3|UniProtKB=G3QGR9 G3QGR9 CER1 PTHR15273:SF4 DAN DOMAIN FAMILY MEMBER 5 CERBERUS signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 determination of left/right symmetry#GO:0007368;cellular response to stimulus#GO:0051716;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regionalization#GO:0003002;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;specification of symmetry#GO:0009799;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;negative regulation of cell communication#GO:0010648;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;determination of bilateral symmetry#GO:0009855;heart development#GO:0007507;left/right pattern formation#GO:0060972;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anterior/posterior axis specification#GO:0009948 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Wnt signaling pathway#P00057>Cerebus#P01445 GORGO|Ensembl=ENSGGOG00000016536.3|UniProtKB=A0A2I2ZEM4 A0A2I2ZEM4 ZMYND11 PTHR46379:SF1 ZINC FINGER MYND DOMAIN-CONTAINING ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11 histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000022813.2|UniProtKB=A0A2I2YFB7 A0A2I2YFB7 PTHR14200:SF12 CYTOCHROME C OXIDASE POLYPEPTIDE CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277 oxidase#PC00175;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000016577.3|UniProtKB=G3RKB2 G3RKB2 TMEM43 PTHR13416:SF2 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 43 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000006308.3|UniProtKB=G3SBV5 G3SBV5 PARP1 PTHR10459:SF112 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 1 catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 GORGO|Ensembl=ENSGGOG00000011124.3|UniProtKB=G3R6A1 G3R6A1 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 670 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010576.3|UniProtKB=G3RZ93 G3RZ93 VSIG1 PTHR44974:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000009450.3|UniProtKB=G3R221 G3R221 MYO15B PTHR22692:SF16 MYOSIN VII, XV UNCONVENTIONAL MYOSIN-XVB actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000003184.3|UniProtKB=G3QKZ3 G3QKZ3 KLHL32 PTHR45632:SF45 LD33804P KELCH-LIKE PROTEIN 32 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009762.3|UniProtKB=G3R2S6 G3R2S6 TFAP2E PTHR10812:SF13 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-EPSILON binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cell population proliferation#GO:0042127;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000011400.3|UniProtKB=A0A2I2YUX4 A0A2I2YUX4 MYO6 PTHR13140:SF745 MYOSIN UNCONVENTIONAL MYOSIN-VI isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146 actin filament-based process#GO:0030029;embryonic organ development#GO:0048568;system development#GO:0048731;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin cytoskeleton organization#GO:0030036;animal organ morphogenesis#GO:0009887;developmental process#GO:0032502;epidermis development#GO:0008544;sensory organ development#GO:0007423;neurogenesis#GO:0022008;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;actin filament-based movement#GO:0030048;inner ear development#GO:0048839;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;ear development#GO:0043583;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;sensory organ morphogenesis#GO:0090596;cell differentiation#GO:0030154;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;hair cell differentiation#GO:0035315;inner ear morphogenesis#GO:0042472;organelle organization#GO:0006996;nervous system development#GO:0007399;embryo development#GO:0009790;cytoskeleton organization#GO:0007010 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;membraneless organelle#GO:0043228;ruffle#GO:0001726;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000010443.3|UniProtKB=G3R4J8 G3R4J8 TPCN1 PTHR46474:SF1 TWO PORE CALCIUM CHANNEL PROTEIN 1 TWO PORE CHANNEL PROTEIN 1 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;lysosomal membrane#GO:0005765;membrane#GO:0016020;vesicle membrane#GO:0012506 ion channel#PC00133 CCKR signaling map#P06959>TPC1/2#P07209 GORGO|Ensembl=ENSGGOG00000010429.3|UniProtKB=G3R4H4 G3R4H4 SLC22A4 PTHR24064:SF222 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 4 quaternary ammonium group transmembrane transporter activity#GO:0015651;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000038795.1|UniProtKB=A0A2I2ZFH6 A0A2I2ZFH6 ASTN2 PTHR16592:SF2 ASTROTACTIN-1-LIKE ASTROTACTIN-2 alcohol binding#GO:0043178;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell motility#GO:0048870;multicellular organism development#GO:0007275;neuron migration#GO:0001764;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell migration#GO:0016477;nervous system development#GO:0007399;cell-cell adhesion#GO:0098609;cellular process#GO:0009987 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000005543.3|UniProtKB=G3QS09 G3QS09 LY6G5B PTHR11740:SF45 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 GORGO|Ensembl=ENSGGOG00000025814.2|UniProtKB=A0A2I2YCF0 A0A2I2YCF0 VTCN1 PTHR24100:SF0 BUTYROPHILIN V-SET DOMAIN-CONTAINING T-CELL ACTIVATION INHIBITOR 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000037461.1|UniProtKB=A0A2I2YI00 A0A2I2YI00 PTHR43655:SF7 ATP-DEPENDENT PROTEASE MITOCHONDRIAL INNER MEMBRANE M-AAA PROTEASE COMPONENT AFG3L1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000036959.1|UniProtKB=A0A2I2Z5U2 A0A2I2Z5U2 RASSF2 PTHR22738:SF14 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 2 signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003057.3|UniProtKB=G3QKM8 G3QKM8 ACOT8 PTHR11066:SF34 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 8 hydrolase activity#GO:0016787;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790 nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;monocarboxylic acid catabolic process#GO:0072329;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000042684.1|UniProtKB=A0A2I2Y9R2 A0A2I2Y9R2 NDUFB2 PTHR15223:SF1 NADH-UBIQUINONE OXIDOREDUCTASE AGGG SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333 membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007422.3|UniProtKB=G3QWU6 G3QWU6 CCNC PTHR10026:SF7 CYCLIN CYCLIN-C cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513 kinase activator#PC00138;kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000016091.3|UniProtKB=A0A2I2Y7G8 A0A2I2Y7G8 CHMP4A PTHR10766:SF177 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 1 cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;localization within membrane#GO:0051668 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023577.2|UniProtKB=G3S9A5 G3S9A5 SNX7 PTHR45949:SF3 SORTING NEXIN-4 SORTING NEXIN-7 catabolic process#GO:0009056;endocytic recycling#GO:0032456;piecemeal microautophagy of the nucleus#GO:0034727;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;macromolecule localization#GO:0033036;reticulophagy#GO:0061709;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;macroautophagy#GO:0016236;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;intracellular transport#GO:0046907;transport#GO:0006810;mitophagy#GO:0000423;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;endosome#GO:0005768 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004103.3|UniProtKB=A0A2I2YZA8 A0A2I2YZA8 LARS1 PTHR45794:SF1 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000001596.3|UniProtKB=G3QGW0 G3QGW0 SLC9A1 PTHR10110:SF59 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 1 antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000013771.3|UniProtKB=G3RD37 G3RD37 LOC101144243 PTHR48416:SF1 CYTOCHROME C OXIDASE SUBUNIT 6C CYTOCHROME C OXIDASE SUBUNIT 6C cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011782.3|UniProtKB=A0A2I2ZKS4 A0A2I2ZKS4 REG3G PTHR22802:SF345 C-TYPE LECTIN SUPERFAMILY MEMBER RERATING FAMILY MEMBER 4 molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000016353.3|UniProtKB=G3RJR6 G3RJR6 ARHGAP11A PTHR15670:SF4 RHO GTPASE ACTIVATING PROTEIN 11A INACTIVE RHO GTPASE-ACTIVATING PROTEIN 11B-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000013357.3|UniProtKB=G3RC12 G3RC12 UBE2M PTHR24068:SF572 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBC12 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000004064.3|UniProtKB=G3QN78 G3QN78 ALX3 PTHR24329:SF578 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARISTALESS-LIKE 3 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000025351.2|UniProtKB=A0A2I2Z1M6 A0A2I2Z1M6 STAU1 PTHR46054:SF2 MATERNAL EFFECT PROTEIN STAUFEN DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 1 double-stranded RNA binding#GO:0003725;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;RNA localization#GO:0006403;gamete generation#GO:0007276;cell differentiation#GO:0030154;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;sexual reproduction#GO:0019953;microtubule-based transport#GO:0099111;protein localization to cell junction#GO:1902414;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;macromolecule localization#GO:0033036;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;protein localization to synapse#GO:0035418;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025 GORGO|Ensembl=ENSGGOG00000010973.3|UniProtKB=G3R5W1 G3R5W1 CRLF1 PTHR23036:SF16 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 1 cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 response to chemical#GO:0042221;response to cytokine#GO:0034097;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of neuron apoptotic process#GO:0043523;negative regulation of neuron apoptotic process#GO:0043524;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002568.3|UniProtKB=G3QJD8 G3QJD8 MYL3 PTHR23048:SF2 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 3 ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;structural molecule activity#GO:0005198;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000006115.3|UniProtKB=G3QTG5 G3QTG5 CD36 PTHR11923:SF12 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 PLATELET GLYCOPROTEIN 4 low-density lipoprotein particle receptor activity#GO:0005041;cargo receptor activity#GO:0038024;protein-containing complex binding#GO:0044877;binding#GO:0005488;lipoprotein particle binding#GO:0071813;protein-lipid complex binding#GO:0071814;low-density lipoprotein particle binding#GO:0030169 carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;metabolic process#GO:0008152;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;plasma lipoprotein particle clearance#GO:0034381;import into cell#GO:0098657;lipid storage#GO:0019915;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;lipid transport#GO:0006869;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;lipid localization#GO:0010876;protein transport#GO:0015031;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;regulation of biological process#GO:0050789;catabolic process#GO:0009056;endocytosis#GO:0006897 plasma membrane#GO:0005886;cell surface#GO:0009986;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane raft#GO:0045121;caveola#GO:0005901;plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000008187.3|UniProtKB=G3QYR8 G3QYR8 DHX57 PTHR18934:SF145 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX57-RELATED nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000023295.2|UniProtKB=A0A2I2ZRQ5 A0A2I2ZRQ5 DENND4C PTHR12296:SF17 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN 4C guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 response to nitrogen compound#GO:1901698;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000002640.3|UniProtKB=G3QJK6 G3QJK6 CNBD2 PTHR23011:SF43 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 2 ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166 developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;gamete generation#GO:0007276;male gamete generation#GO:0048232;spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609 GORGO|Ensembl=ENSGGOG00000010501.3|UniProtKB=A0A2I2ZAL0 A0A2I2ZAL0 ZNF507 PTHR24409:SF448 ZINC FINGER PROTEIN 142 C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016222.3|UniProtKB=G3RJF5 G3RJF5 TONSL PTHR46358:SF1 TONSOKU-LIKE PROTEIN TONSOKU-LIKE PROTEIN cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;response to stress#GO:0006950;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000014464.3|UniProtKB=G3REW1 G3REW1 PTHR24055:SF146 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 12 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;p38 MAPK pathway#P05918>p38gamma#P06015;Ras Pathway#P04393>p38#P04558;Oxidative stress response#P00046>p38#P01135;B cell activation#P00010>p38#P00384;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>p38#P00562;TGF-beta signaling pathway#P00052>P38#P01275;Parkinson disease#P00049>SAPK#P01219;FGF signaling pathway#P00021>p38#P00644;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831 GORGO|Ensembl=ENSGGOG00000014889.3|UniProtKB=G3RG00 G3RG00 BCOR PTHR24117:SF8 AGAP007537-PB BCL-6 COREPRESSOR transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000016608.3|UniProtKB=A0A2I2Z996 A0A2I2Z996 POLR3B PTHR20856:SF8 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA transcription#GO:0009301;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA transcription by RNA polymerase III#GO:0042796;snRNA metabolic process#GO:0016073 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000039974.1|UniProtKB=A0A2I2YAD7 A0A2I2YAD7 CMPK1 PTHR23359:SF206 NUCLEOTIDE KINASE UMP-CMP KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776 ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nucleoside diphosphate metabolic process#GO:0009132;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153;De novo pyrimidine ribonucleotides biosythesis#P02740>Uridylate kinase#P02924 GORGO|Ensembl=ENSGGOG00000013959.3|UniProtKB=G3RDK8 G3RDK8 KBTBD4 PTHR47195:SF1 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000022219.2|UniProtKB=A0A2I2Y6Y4 A0A2I2Y6Y4 PTHR48002:SF63 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003510.3|UniProtKB=G3QLT1 G3QLT1 TFAP2D PTHR10812:SF5 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-DELTA DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000016889.3|UniProtKB=G3RL39 G3RL39 PLAGL1 PTHR24390:SF64 ZINC FINGER PROTEIN PLEIOMORPHIC ADENOMA GENE-LIKE 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005862.3|UniProtKB=G3QSU0 G3QSU0 MAT1A PTHR11964:SF11 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987;biosynthetic process#GO:0009058 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174;transferase#PC00220 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 GORGO|Ensembl=ENSGGOG00000038788.1|UniProtKB=G3REB4 G3REB4 LOC101130441 PTHR11848:SF257 TGF-BETA FAMILY LEFT-RIGHT DETERMINATION FACTOR 1 receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 response to endogenous stimulus#GO:0009719;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;signaling#GO:0023052;pattern specification process#GO:0007389;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;regionalization#GO:0003002;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;anterior/posterior pattern specification#GO:0009952;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;developmental process#GO:0032502;cellular response to BMP stimulus#GO:0071773;anterior/posterior axis specification#GO:0009948;multicellular organism development#GO:0007275 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000016769.3|UniProtKB=G3RKS6 G3RKS6 C7H8orf33 PTHR13602:SF2 UPF0488 PROTEIN C8ORF33 UPF0488 PROTEIN C8ORF33 GORGO|Ensembl=ENSGGOG00000001470.3|UniProtKB=G3QGJ5 G3QGJ5 CHDH PTHR11552:SF231 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE CHOLINE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000040998.1|UniProtKB=A0A2I2ZUY2 A0A2I2ZUY2 KCNJ12 PTHR11767:SF14 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 12-RELATED transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000005428.3|UniProtKB=G3QRQ8 G3QRQ8 HDAC2 PTHR10625:SF3 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 2 catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993 regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>Histone deacetylase#P01472;p53 pathway#P00059>HDAC1#P04612 GORGO|Ensembl=ENSGGOG00000000142.3|UniProtKB=G3QD37 G3QD37 CNOT4 PTHR12603:SF0 CCR4-NOT TRANSCRIPTION COMPLEX RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;protein metabolic process#GO:0019538;regulation of RNA stability#GO:0043487;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;protein catabolic process#GO:0030163;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;CCR4-NOT complex#GO:0030014 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000037214.1|UniProtKB=G3QHF4 G3QHF4 OR7D2 PTHR26453:SF626 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003966.3|UniProtKB=G3QMZ3 G3QMZ3 KBTBD3 PTHR24412:SF418 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 3 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000038551.1|UniProtKB=G3RY22 G3RY22 PTHR37553:SF10 DUF4705 DOMAIN-CONTAINING PROTEIN DUF4705 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000038720.1|UniProtKB=A0A2I2Z8L1 A0A2I2Z8L1 CENPVL3 PTHR28620:SF8 CENTROMERE PROTEIN V CENTROMERE PROTEIN V-LIKE PROTEIN 2 GORGO|Ensembl=ENSGGOG00000000637.3|UniProtKB=G3QED5 G3QED5 GSTO2 PTHR43968:SF4 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA-2 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;glutathione transferase activity#GO:0004364 glutathione metabolic process#GO:0006749;monosaccharide metabolic process#GO:0005996;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;L-ascorbic acid metabolic process#GO:0019852;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000028180.3|UniProtKB=A0A2I2YJ53 A0A2I2YJ53 TMTC2 PTHR44216:SF3 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000000512.3|UniProtKB=G3QE18 G3QE18 STIL PTHR15128:SF0 TAL1 SCL INTERRUPTING LOCUS SCL-INTERRUPTING LOCUS PROTEIN macromolecule localization#GO:0033036;biological regulation#GO:0065007;protein localization to microtubule cytoskeleton#GO:0072698;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;protein localization to centrosome#GO:0071539;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;smoothened signaling pathway#GO:0007224;cell communication#GO:0007154;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell surface receptor signaling pathway#GO:0007166;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;protein localization to microtubule organizing center#GO:1905508 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000013581.3|UniProtKB=A0A2I2ZK20 A0A2I2ZK20 EML3 PTHR13720:SF15 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 3 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000037695.1|UniProtKB=A0A2I2ZY94 A0A2I2ZY94 ZNF776 PTHR24377:SF725 IP01015P-RELATED ZINC FINGER PROTEIN 776 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015295.3|UniProtKB=G3RH07 G3RH07 MICALL2 PTHR23167:SF87 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED MICAL-LIKE PROTEIN 2 cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010274.3|UniProtKB=G3R438 G3R438 RBP2 PTHR11955:SF59 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 2 organic acid binding#GO:0043177;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;fatty acid binding#GO:0005504 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000027369.2|UniProtKB=G3S7R1 G3S7R1 PTHR23074:SF173 AAA DOMAIN-CONTAINING SPASTIN hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543 plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell projection organization#GO:0030030;neuron projection morphogenesis#GO:0048812;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000001328.3|UniProtKB=G3QG60 G3QG60 ASNSD1 PTHR45937:SF2 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 animal organ development#GO:0048513;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;connective tissue development#GO:0061448;muscle organ development#GO:0007517;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;tissue development#GO:0009888;muscle structure development#GO:0061061;skeletal muscle tissue development#GO:0007519 GORGO|Ensembl=ENSGGOG00000001298.4|UniProtKB=G3QG32 G3QG32 MAGI2 PTHR10316:SF27 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 2 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 macromolecule localization#GO:0033036;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of protein localization to membrane#GO:1905475;biological regulation#GO:0065007;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;protein localization to membrane#GO:0072657;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;receptor clustering#GO:0043113;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cell communication#GO:0007154;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880 adherens junction#GO:0005912;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection#GO:0043005;cell-cell junction#GO:0005911 GORGO|Ensembl=ENSGGOG00000010685.3|UniProtKB=G3R552 G3R552 IFT25 PTHR33906:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;spermatogenesis#GO:0007283;male gamete generation#GO:0048232;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;multicellular organismal reproductive process#GO:0048609;smoothened signaling pathway#GO:0007224;sexual reproduction#GO:0019953;gamete generation#GO:0007276;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;reproductive process#GO:0022414;signaling#GO:0023052;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;intraciliary transport particle#GO:0030990;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intraciliary transport particle B#GO:0030992;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 GORGO|Gene=TGIF2LX|UniProtKB=Q8MIE9 Q8MIE9 TGIF2LX PTHR11850:SF205 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF2LX-RELATED DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000039519.1|UniProtKB=A0A2I2YFF0 A0A2I2YFF0 LOC101132260 PTHR26453:SF680 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2L3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000035.3|UniProtKB=A0A2I2Z313 A0A2I2Z313 CMIP PTHR25480:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 73 C-MAF-INDUCING PROTEIN membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007578.3|UniProtKB=G3S5Q3 G3S5Q3 ADRB3 PTHR24248:SF3 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-3 ADRENERGIC RECEPTOR G protein-coupled amine receptor activity#GO:0008227;hormone binding#GO:0042562;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;cellular process#GO:0009987;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;biological regulation#GO:0065007;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of anatomical structure size#GO:0090066;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;vasodilation#GO:0042311;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Beta3 adrenergic receptor signaling pathway#P04379>Beta3#P04449 GORGO|Ensembl=ENSGGOG00000025923.2|UniProtKB=G3SF59 G3SF59 PATL2 PTHR21551:SF3 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PROTEIN PAT1 HOMOLOG 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;cellular component assembly#GO:0022607;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;organelle assembly#GO:0070925;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;RNA destabilization#GO:0050779;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of RNA metabolic process#GO:0051254;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;P-body assembly#GO:0033962;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;RNA decapping#GO:0110154;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000026920.2|UniProtKB=A0A2I2YQN5 A0A2I2YQN5 CCDC181 PTHR14320:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 GORGO|Ensembl=ENSGGOG00000009026.3|UniProtKB=G3R0X4 G3R0X4 CD300C PTHR11860:SF107 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of response to biotic stimulus#GO:0002831;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000011518.3|UniProtKB=G3R7A0 G3R7A0 PTHR23290:SF0 RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 RRNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL5 catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414 GORGO|Ensembl=ENSGGOG00000011158.3|UniProtKB=G3R6C5 G3R6C5 RARRES2 PTHR15106:SF2 RETINOIC ACID RECEPTOR RESPONDER PROTEIN 2 RETINOIC ACID RECEPTOR RESPONDER PROTEIN 2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of chemotaxis#GO:0050921;regulation of lipid metabolic process#GO:0019216;immune system process#GO:0002376;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of chemotaxis#GO:0050920;regulation of lipid catabolic process#GO:0050994;regulation of biological process#GO:0050789;innate immune response#GO:0045087;positive regulation of response to external stimulus#GO:0032103;regulation of catabolic process#GO:0009894;defense response#GO:0006952;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;response to biotic stimulus#GO:0009607;regulation of primary metabolic process#GO:0080090;immune response#GO:0006955;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008181.3|UniProtKB=G3RZJ6 G3RZJ6 LEO1 PTHR23146:SF0 LEO1 PROTEIN RNA POLYMERASE-ASSOCIATED PROTEIN LEO1 binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;transcription coregulator activity#GO:0003712;RNA polymerase binding#GO:0070063;RNA polymerase core enzyme binding#GO:0043175 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000000304.3|UniProtKB=G3SHU4 G3SHU4 CDK11B PTHR24056:SF599 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 11A-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000010857.3|UniProtKB=A0A2I2ZSQ9 A0A2I2ZSQ9 FIBP PTHR13223:SF2 ACIDIC FIBROBLAST GROWTH FACTOR INTRACELLULAR BINDING PROTEIN ACIDIC FIBROBLAST GROWTH FACTOR INTRACELLULAR-BINDING PROTEIN binding#GO:0005488;fibroblast growth factor binding#GO:0017134;protein binding#GO:0005515;growth factor binding#GO:0019838 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000043521.1|UniProtKB=A0A2I2Z0P7 A0A2I2Z0P7 PTHR11224:SF45 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005671.3|UniProtKB=G3QSC2 G3QSC2 FBP1 PTHR11556:SF11 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;glucose metabolic process#GO:0006006;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987;hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;carbohydrate phosphatase#PC00066;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000003667.3|UniProtKB=A0A2I2YZY3 A0A2I2YZY3 TCF3 PTHR11793:SF14 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR E2-ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;gene expression#GO:0010467;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;multicellular organism development#GO:0007275;V(D)J recombination#GO:0033151;regulation of biological process#GO:0050789;production of molecular mediator of immune response#GO:0002440;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;immune system development#GO:0002520;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;somatic cell DNA recombination#GO:0016444;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;somatic diversification of immune receptors#GO:0002200;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000015132.3|UniProtKB=G3RGL4 G3RGL4 CST9L PTHR46945:SF1 CYSTATIN-9-LIKE CYSTATIN-9-LIKE response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000003366.3|UniProtKB=G3QLF6 G3QLF6 ZNF530 PTHR23226:SF432 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015182.3|UniProtKB=G3RGQ5 G3RGQ5 SLC25A34 PTHR45928:SF3 RE38146P SOLUTE CARRIER FAMILY 25 MEMBER 34 GORGO|Ensembl=ENSGGOG00000015841.3|UniProtKB=G3RIE8 G3RIE8 ZNF746 PTHR23232:SF118 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 746-RELATED sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000043502.1|UniProtKB=A0A2I2ZGB4 A0A2I2ZGB4 FAM9C PTHR19368:SF6 XLR/SCP3/FAM9 PROTEIN FAM9C developmental process involved in reproduction#GO:0003006;cell cycle#GO:0007049;germ cell development#GO:0007281;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;cellular process#GO:0009987;male gamete generation#GO:0048232;meiotic cell cycle#GO:0051321;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869 condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;synaptonemal structure#GO:0099086;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 GORGO|Ensembl=ENSGGOG00000013843.3|UniProtKB=A0A2I2YA69 A0A2I2YA69 DDX46 PTHR24031:SF25 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX46-RELATED macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006579.3|UniProtKB=G3QUN3 G3QUN3 AGXT2 PTHR45688:SF3 FAMILY NOT NAMED ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL GORGO|Ensembl=ENSGGOG00000006637.3|UniProtKB=G3QUT6 G3QUT6 ATG3 PTHR12866:SF2 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 ubiquitin-like protein conjugating enzyme activity#GO:0061650;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;autophagosome assembly#GO:0000045;autophagy of mitochondrion#GO:0000422;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;organelle organization#GO:0006996;glycogen catabolic process#GO:0005980;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;polysaccharide catabolic process#GO:0000272 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000009409.3|UniProtKB=G3S190 G3S190 WDR37 PTHR19855:SF12 WD40 REPEAT PROTEIN 12, 37 WD REPEAT-CONTAINING PROTEIN 37 GORGO|Ensembl=ENSGGOG00000000307.3|UniProtKB=G3RQZ2 G3RQZ2 NADK PTHR20275:SF44 NAD KINASE NAD KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000026953.2|UniProtKB=G3S2M0 G3S2M0 LOC101142669 PTHR28620:SF7 CENTROMERE PROTEIN V CENTROMERE PROTEIN V-LIKE PROTEIN 3 GORGO|Ensembl=ENSGGOG00000013490.3|UniProtKB=A0A2I2YYI8 A0A2I2YYI8 ZDHHC3 PTHR22883:SF246 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC3 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular localization#GO:0051641;localization#GO:0051179;regulation of signaling#GO:0023051;localization within membrane#GO:0051668;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;protein targeting#GO:0006605;regulation of biological process#GO:0050789;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;protein localization to cell periphery#GO:1990778;protein targeting to membrane#GO:0006612;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000014551.3|UniProtKB=G3RF38 G3RF38 MFGE8 PTHR24543:SF317 MULTICOPPER OXIDASE-RELATED LACTADHERIN ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000027445.2|UniProtKB=G3RS25 G3RS25 NFIA PTHR11492:SF6 NUCLEAR FACTOR I NUCLEAR FACTOR 1 A-TYPE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000007895.3|UniProtKB=G3QY09 G3QY09 PIAS4 PTHR10782:SF9 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS4 molecular function inhibitor activity#GO:0140678;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;metabolic process#GO:0008152;protein sumoylation#GO:0016925 membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958;JAK/STAT signaling pathway#P00038>PIAS#P01031 GORGO|Ensembl=ENSGGOG00000005582.3|UniProtKB=G3QS41 G3QS41 ANXA9 PTHR10502:SF122 ANNEXIN ANNEXIN A9 phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular process#GO:0009987;cell adhesion#GO:0007155 nucleus#GO:0005634;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000016660.3|UniProtKB=G3RKI6 G3RKI6 DIPK2B PTHR32073:SF8 GH11358P DIVERGENT PROTEIN KINASE DOMAIN 2B GORGO|Ensembl=ENSGGOG00000011790.3|UniProtKB=G3R803 G3R803 MDH2 PTHR11540:SF76 MALATE AND LACTATE DEHYDROGENASE MALATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000001201.3|UniProtKB=A0A2I2Y756 A0A2I2Y756 CACNA1S PTHR45628:SF9 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1S monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 voltage-gated ion channel#PC00241 5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812 GORGO|Ensembl=ENSGGOG00000016365.3|UniProtKB=G3RJT0 G3RJT0 HDAC3 PTHR10625:SF36 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 3 deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974 Wnt signaling pathway#P00057>Histone deacetylase#P01472 GORGO|Ensembl=ENSGGOG00000016335.3|UniProtKB=G3S7V3 G3S7V3 RIGI PTHR14074:SF16 HELICASE WITH DEATH DOMAIN-RELATED ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I double-stranded RNA binding#GO:0003725;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;cation binding#GO:0043169;RNA binding#GO:0003723;metal ion binding#GO:0046872;zinc ion binding#GO:0008270;single-stranded RNA binding#GO:0003727 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000007550.3|UniProtKB=G3SDT7 G3SDT7 GNL3L PTHR11089:SF33 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3-LIKE PROTEIN intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 GORGO|Ensembl=ENSGGOG00000003141.4|UniProtKB=A0A2I2ZN14 A0A2I2ZN14 MAPK10 PTHR24055:SF162 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 10 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Angiogenesis#P00005>JNK1#P00221;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Ras Pathway#P04393>JNK#P04572;B cell activation#P00010>Jnk#P00402;PDGF signaling pathway#P00047>ERK#P01143;CCKR signaling map#P06959>MAPK8-10#P07090;Apoptosis signaling pathway#P00006>JNK#P00274;Integrin signalling pathway#P00034>ERK#P00907;Parkinson disease#P00049>SAPK#P01219;Toll receptor signaling pathway#P00054>JNK#P01375;Oxidative stress response#P00046>JNK1/2#P01129;FGF signaling pathway#P00021>JNK1-3#P00628;TGF-beta signaling pathway#P00052>JNK#P01284;T cell activation#P00053>Jnk#P01336;FAS signaling pathway#P00020>JNK#P00615;EGF receptor signaling pathway#P00018>JNK1-3#P00545;Integrin signalling pathway#P00034>Jnk#P00951 GORGO|Ensembl=ENSGGOG00000028567.2|UniProtKB=A0A2I2Y4M1 A0A2I2Y4M1 CRB1 PTHR24049:SF1 CRUMBS FAMILY MEMBER PROTEIN CRUMBS HOMOLOG 1 establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of bipolar cell polarity#GO:0061245;cell adhesion#GO:0007155;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000024798.2|UniProtKB=G3S026 G3S026 PTHR15566:SF4 POM121-LIKE POM121-LIKE PROTEIN 1-RELATED GORGO|Ensembl=ENSGGOG00000010688.3|UniProtKB=G3SGQ0 G3SGQ0 LOC109024635 PTHR14112:SF23 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX5 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000000417.3|UniProtKB=G3QDT4 G3QDT4 EPDR1 PTHR10697:SF1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323 GORGO|Ensembl=ENSGGOG00000026321.2|UniProtKB=G3RWD8 G3RWD8 FGA PTHR47221:SF3 FIBRINOGEN ALPHA CHAIN FIBRINOGEN ALPHA CHAIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein maturation#GO:0051604;regulation of response to external stimulus#GO:0032101;gene expression#GO:0010467;fibrinolysis#GO:0042730;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;positive regulation of cell-cell adhesion#GO:0022409;regulation of response to wounding#GO:1903034;cellular process#GO:0009987;coagulation#GO:0050817;positive regulation of biological process#GO:0048518;negative regulation of response to wounding#GO:1903035;metabolic process#GO:0008152;platelet aggregation#GO:0070527;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;response to stimulus#GO:0050896;regulation of wound healing#GO:0061041;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of coagulation#GO:0050819;protein activation cascade#GO:0072376;regulation of biological quality#GO:0065008;wound healing#GO:0042060;negative regulation of hemostasis#GO:1900047;cell adhesion#GO:0007155;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of response to stimulus#GO:0048585;regulation of coagulation#GO:0050818;homotypic cell-cell adhesion#GO:0034109;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of wound healing#GO:0061045;response to wounding#GO:0009611;macromolecule biosynthetic process#GO:0009059;regulation of hemostasis#GO:1900046;positive regulation of cellular process#GO:0048522;macromolecule metabolic process#GO:0043170;platelet activation#GO:0030168;blood coagulation#GO:0007596;negative regulation of blood coagulation#GO:0030195;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;hemostasis#GO:0007599;negative regulation of multicellular organismal process#GO:0051241;positive regulation of cell adhesion#GO:0045785;protein metabolic process#GO:0019538;cell activation#GO:0001775;blood coagulation, fibrin clot formation#GO:0072378 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 Plasminogen activating cascade#P00050>Fibrin C-terminal truncation#P01258;Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin monomer#P00418;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443;Blood coagulation#P00011>Fibrinogen#P00406 GORGO|Ensembl=ENSGGOG00000038623.1|UniProtKB=A0A2I2Z8W1 A0A2I2Z8W1 PEX2 PTHR48178:SF3 PEROXISOME BIOGENESIS FACTOR 2 PEROXISOME BIOGENESIS FACTOR 2 monocarboxylic acid metabolic process#GO:0032787;cellular component organization#GO:0016043;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;peroxisome organization#GO:0007031;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;organelle organization#GO:0006996;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;lipid modification#GO:0030258;cellular component organization or biogenesis#GO:0071840 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;peroxisomal membrane#GO:0005778;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;microbody#GO:0042579;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000037600.1|UniProtKB=A0A2I2Y538 A0A2I2Y538 XIRP2 PTHR22591:SF1 XIN XIN ACTIN-BINDING REPEAT-CONTAINING PROTEIN 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cell junction#GO:0030054;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;organelle#GO:0043226;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;intracellular membraneless organelle#GO:0043232;cell-substrate junction#GO:0030055 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000026860.2|UniProtKB=G3RN17 G3RN17 LOC101150965 PTHR24381:SF366 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004302.3|UniProtKB=G3QNU6 G3QNU6 TMEM106C PTHR28556:SF5 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106C GORGO|Ensembl=ENSGGOG00000016653.3|UniProtKB=G3RKI3 G3RKI3 IL1RL1 PTHR11890:SF7 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR-LIKE 1 binding#GO:0005488;protein binding#GO:0005515;cytokine binding#GO:0019955 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;biological regulation#GO:0065007;signaling#GO:0023052 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016396.3|UniProtKB=G3RJU5 G3RJU5 HBQ1 PTHR11442:SF15 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT THETA-1 tetrapyrrole binding#GO:0046906;binding#GO:0005488;molecular carrier activity#GO:0140104;heme binding#GO:0020037 cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;cell development#GO:0048468;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;localization#GO:0051179;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;cellular process#GO:0009987;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219;globin#PC00107 GORGO|Ensembl=ENSGGOG00000016803.3|UniProtKB=G3QMC2 G3QMC2 PTHR19970:SF1 RIBOSOMAL PROTEIN L39E SUBFAMILY NOT NAMED structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasmic translation#GO:0002181;gamete generation#GO:0007276;protein biosynthetic process#GO:0160307;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;translation#GO:0006412;male gamete generation#GO:0048232;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;spermatogenesis#GO:0007283;developmental process#GO:0032502 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003489.3|UniProtKB=A0A2I2YHM5 A0A2I2YHM5 LIMK2 PTHR46485:SF1 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000034862.2|UniProtKB=G3SKG6 G3SKG6 WDR27 PTHR44525:SF1 WD REPEAT-CONTAINING PROTEIN 27 WD REPEAT-CONTAINING PROTEIN 27 GORGO|Ensembl=ENSGGOG00000013515.3|UniProtKB=G3RCF5 G3RCF5 ASGR2 PTHR22802:SF433 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR 2 pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000002468.3|UniProtKB=G3QJ50 G3QJ50 COL6A3 PTHR24020:SF13 COLLAGEN ALPHA COLLAGEN ALPHA-3(VI) CHAIN extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863 GORGO|Ensembl=ENSGGOG00000027456.2|UniProtKB=A0A2I2YWW6 A0A2I2YWW6 PTHR12161:SF51 IST1 FAMILY MEMBER IST1 HOMOLOG localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036 GORGO|Ensembl=ENSGGOG00000009422.3|UniProtKB=G3R1X5 G3R1X5 ENTREP3 PTHR17615:SF7 PROTEIN FAM189A PROTEIN ENTREP3 GORGO|Ensembl=ENSGGOG00000026902.2|UniProtKB=G3RXT9 G3RXT9 DMP1 PTHR23400:SF0 DENTIN MATRIX ACIDIC PHOSPHOPROTEIN 1 DENTIN MATRIX ACIDIC PHOSPHOPROTEIN 1 extracellular matrix binding#GO:0050840;binding#GO:0005488 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007395.3|UniProtKB=G3SED9 G3SED9 LOC101136962 PTHR12428:SF70 OXA1 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;respiratory chain complex IV assembly#GO:0008535;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;protein insertion into membrane#GO:0051205;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016368.3|UniProtKB=G3RJS2 G3RJS2 ARTN PTHR12173:SF9 GDNF SUBFAMILY OF TGF-BETA FAMILY ARTEMIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;generation of neurons#GO:0048699 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112;neurotrophic factor#PC00163 GORGO|Ensembl=ENSGGOG00000036703.1|UniProtKB=A0A2I2Y1N6 A0A2I2Y1N6 LOC109024489 PTHR20981:SF8 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012598.3|UniProtKB=G3RA31 G3RA31 SGMS2 PTHR21290:SF24 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 2 phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;ceramide metabolic process#GO:0006672;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000004861.3|UniProtKB=G3QQA3 G3QQA3 AAK1 PTHR47907:SF3 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN AP2-ASSOCIATED PROTEIN KINASE 1 protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049 presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000003832.3|UniProtKB=G3QMN0 G3QMN0 PTHR22762:SF63 ALPHA-GLUCOSIDASE MALTASE-GLUCOAMYLASE alpha-glucosidase activity#GO:0090599;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;glucosidase activity#GO:0015926 glucosidase#PC00108 GORGO|Ensembl=ENSGGOG00000012718.3|UniProtKB=G3RAF1 G3RAF1 MIB1 PTHR24202:SF53 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;localization#GO:0051179;cell communication#GO:0007154;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;signaling#GO:0023052;metabolic process#GO:0008152;transport#GO:0006810;cell surface receptor signaling pathway#GO:0007166;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;import into cell#GO:0098657;Notch signaling pathway#GO:0007219;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000006245.3|UniProtKB=G3QTS9 G3QTS9 SPSB3 PTHR12245:SF5 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000000805.3|UniProtKB=A0A2I2Z7D5 A0A2I2Z7D5 DNAAF11 PTHR18849:SF21 LEUCINE RICH REPEAT PROTEIN DYNEIN AXONEMAL ASSEMBLY FACTOR 11 cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;organelle assembly#GO:0070925;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000006280.3|UniProtKB=G3QTV9 G3QTV9 PTHR31395:SF14 SHISA PROTEIN SHISA-5 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000043233.1|UniProtKB=G3SGM4 G3SGM4 LOC101150195 PTHR12002:SF224 CLAUDIN CLAUDIN-22 cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987 bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000000971.3|UniProtKB=G3QF88 G3QF88 HMGN2 PTHR23087:SF13 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-17 binding#GO:0005488;chromatin binding#GO:0003682 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004146.3|UniProtKB=G3QNF3 G3QNF3 ATP6V1C1 PTHR10137:SF5 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 1 monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078 proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000014676.3|UniProtKB=G3RFF6 G3RFF6 PPP4R3B PTHR23318:SF18 ATP SYNTHASE GAMMA-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3B protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;enzyme activator activity#GO:0008047 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of DNA metabolic process#GO:0051052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;cellular response to stress#GO:0033554;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;DNA damage response#GO:0006974 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000001997.3|UniProtKB=G3RRN0 G3RRN0 PTHR16675:SF289 MHC CLASS I-RELATED ZINC-ALPHA-2-GLYCOPROTEIN positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015579.3|UniProtKB=G3RHS0 G3RHS0 ZNF23 PTHR24409:SF331 ZINC FINGER PROTEIN 142 C2H2-TYPE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000028581.2|UniProtKB=G3SGF5 G3SGF5 TMEM52B PTHR33955:SF1 TRANSMEMBRANE PROTEIN 52 TRANSMEMBRANE PROTEIN 52B GORGO|Ensembl=ENSGGOG00000013646.3|UniProtKB=G3RCS8 G3RCS8 IBA57 PTHR22602:SF0 IRON-SULFUR CLUSTER ASSEMBLY FACTOR CAF17/IBA57, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY FACTOR IBA57, MITOCHONDRIAL cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002746.3|UniProtKB=G3QJV1 G3QJV1 NLRC4 PTHR47688:SF1 NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000013969.3|UniProtKB=G3RDM1 G3RDM1 TMEM184A PTHR23423:SF59 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010892.3|UniProtKB=G3R5N2 G3R5N2 CFAP144 PTHR33865:SF2 PROTEIN FAM183B CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 144 cilium#GO:0005929;ciliary base#GO:0097546;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014523.3|UniProtKB=G3RN05 G3RN05 PDE8A PTHR11347:SF85 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 positive regulation of signal transduction#GO:0009967;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;cellular response to growth factor stimulus#GO:0071363;negative regulation of cell communication#GO:0010648;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000000330.4|UniProtKB=G3QDK3 G3QDK3 LPIN2 PTHR12181:SF11 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN2 catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid catabolic process#GO:0016042;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;regulation of biological process#GO:0050789;carboxylic acid metabolic process#GO:0019752;response to endogenous stimulus#GO:0009719;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;glycerolipid biosynthetic process#GO:0045017;carboxylic acid catabolic process#GO:0046395;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;response to peptide hormone#GO:0043434;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;monocarboxylic acid catabolic process#GO:0072329;cellular response to nitrogen compound#GO:1901699;positive regulation of DNA-templated transcription#GO:0045893;lipid biosynthetic process#GO:0008610;regulation of nucleobase-containing compound metabolic process#GO:0019219;triglyceride biosynthetic process#GO:0019432;triglyceride metabolic process#GO:0006641;cellular response to insulin stimulus#GO:0032869;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;acylglycerol metabolic process#GO:0006639;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;neutral lipid metabolic process#GO:0006638;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000003437.3|UniProtKB=G3QLL9 G3QLL9 RAMP2 PTHR14076:SF9 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;coreceptor activity#GO:0015026 metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;system development#GO:0048731;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;anatomical structure development#GO:0048856;localization within membrane#GO:0051668;biological regulation#GO:0065007;tube development#GO:0035295;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036;receptor-mediated endocytosis#GO:0006898;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;cellular response to hormone stimulus#GO:0032870;endocytosis#GO:0006897;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;blood vessel morphogenesis#GO:0048514;monoatomic ion transport#GO:0006811;protein transport#GO:0015031;cellular localization#GO:0051641;angiogenesis#GO:0001525;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;response to chemical#GO:0042221;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;cellular process#GO:0009987;receptor internalization#GO:0031623;response to hormone#GO:0009725;anatomical structure formation involved in morphogenesis#GO:0048646;calcium ion transport#GO:0006816;vasculature development#GO:0001944;multicellular organism development#GO:0007275;import into cell#GO:0098657;protein localization to cell periphery#GO:1990778 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000024279.2|UniProtKB=A0A2I2YKW7 A0A2I2YKW7 PTHR12387:SF3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;proteasome regulatory particle, lid subcomplex#GO:0008541;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000008581.3|UniProtKB=G3QZS2 G3QZS2 TMT1B PTHR45036:SF6 METHYLTRANSFERASE LIKE 7B THIOL S-METHYLTRANSFERASE TMT1B methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000001197.3|UniProtKB=G3S6F9 G3S6F9 KIF21B PTHR24115:SF893 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF21B ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000022202.2|UniProtKB=G3SF48 G3SF48 SCGB2A1 PTHR14037:SF4 MAMMAGLOBIN-RELATED MAMMAGLOBIN-B cellular response to steroid hormone stimulus#GO:0071383;nuclear receptor-mediated signaling pathway#GO:0141193;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;cellular process#GO:0009987;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;intracellular signal transduction#GO:0035556;cellular response to chemical stimulus#GO:0070887;response to steroid hormone#GO:0048545;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;intracellular receptor signaling pathway#GO:0030522;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;steroid hormone receptor signaling pathway#GO:0043401;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000001101.3|UniProtKB=G3SI03 G3SI03 ZIC1 PTHR19818:SF141 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011652.3|UniProtKB=G3R7M0 G3R7M0 CALHM2 PTHR32261:SF3 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 2 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000042970.1|UniProtKB=A0A2I2YS95 A0A2I2YS95 ARL4D PTHR11711:SF137 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4D GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 GORGO|Ensembl=ENSGGOG00000024507.2|UniProtKB=G3SHU1 G3SHU1 OR14J1 PTHR26452:SF42 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14J1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000009972.3|UniProtKB=G3RVH6 G3RVH6 RBM42 PTHR47640:SF11 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED RNA-BINDING PROTEIN 42 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 GORGO|Ensembl=ENSGGOG00000007883.3|UniProtKB=A0A2I2YL11 A0A2I2YL11 PTHR21255:SF20 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 3 binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000022463.2|UniProtKB=G3RW41 G3RW41 FOXJ2 PTHR46078:SF1 FORKHEAD BOX PROTEIN J2 FAMILY MEMBER FORKHEAD BOX PROTEIN J2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000004647.3|UniProtKB=G3QPQ1 G3QPQ1 FGF10 PTHR11486:SF21 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 10 protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;locomotion#GO:0040011;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;system development#GO:0048731;chemotaxis#GO:0006935;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to wounding#GO:0009611;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;wound healing#GO:0042060;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;response to chemical#GO:0042221;taxis#GO:0042330;nervous system development#GO:0007399;response to stress#GO:0006950;positive chemotaxis#GO:0050918;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000013926.3|UniProtKB=G3RDH8 G3RDH8 CSNK1A1 PTHR11909:SF84 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;CCKR signaling map#P06959>CK1#P07049;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Parkinson disease#P00049>Casein kinase I#P01242 GORGO|Ensembl=ENSGGOG00000027735.2|UniProtKB=G3RXF9 G3RXF9 PTHR26453:SF196 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AE1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009779.3|UniProtKB=G3R2T8 G3R2T8 FGF20 PTHR11486:SF72 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 20 protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000007510.3|UniProtKB=A0A2I2YGY5 A0A2I2YGY5 PTHR11064:SF104 CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008662.3|UniProtKB=A0A2I2YD01 A0A2I2YD01 UGT3A1 PTHR48043:SF112 EG:EG0003.4 PROTEIN-RELATED UDP-GLYCOSYLTRANSFERASE 3A1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;transferase complex, transferring phosphorus-containing groups#GO:0061695;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000008748.3|UniProtKB=G3R074 G3R074 ZNF556 PTHR24379:SF136 KRAB AND ZINC FINGER DOMAIN-CONTAINING TRANSCRIPTION FACTOR E4F1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011230.3|UniProtKB=G3R6J2 G3R6J2 ENTREP1 PTHR17615:SF8 PROTEIN FAM189A ENDOSOMAL TRANSMEMBRANE EPSIN INTERACTOR 1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to chemokine#GO:1990869;signaling#GO:0023052;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;localization#GO:0051179;cellular process#GO:0009987;signal transduction#GO:0007165;receptor internalization#GO:0031623;response to chemokine#GO:1990868;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;recycling endosome#GO:0055037;early endosome membrane#GO:0031901 GORGO|Ensembl=ENSGGOG00000000942.3|UniProtKB=A0A2I2YJ95 A0A2I2YJ95 TAF1C PTHR15319:SF1 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription by RNA polymerase I#P00022>TAF-IC#P00649;General transcription regulation#P00023>TBP-associated factors#P00658 GORGO|Ensembl=ENSGGOG00000016441.3|UniProtKB=A0A2I2ZU18 A0A2I2ZU18 CPEB3 PTHR12566:SF7 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 3 translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730;translation factor activity#GO:0180051;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;system process#GO:0003008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;cognition#GO:0050890;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;negative regulation of metabolic process#GO:0009892;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;negative regulation of translation#GO:0017148;regulation of synapse organization#GO:0050807;nervous system process#GO:0050877 nucleus#GO:0005634;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular organelle#GO:0043229;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000025802.2|UniProtKB=G3S7Z1 G3S7Z1 LOC101136057 PTHR26453:SF570 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000041273.1|UniProtKB=A0A2I2ZR04 A0A2I2ZR04 PTHR21346:SF8 FUN14 DOMAIN CONTAINING FUNDC1 catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular process#GO:0009987;autophagy#GO:0006914 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000007521.3|UniProtKB=G3QX33 G3QX33 OSBPL11 PTHR10972:SF46 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 11 sterol binding#GO:0032934;binding#GO:0005488;steroid binding#GO:0005496;lipid binding#GO:0008289 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000027999.2|UniProtKB=G3S8A9 G3S8A9 IFT46 PTHR13376:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intraciliary transport particle B#GO:0030992;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000011236.3|UniProtKB=G3R6J6 G3R6J6 KRT26 PTHR23239:SF162 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 26 structural molecule activity#GO:0005198 intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000005938.4|UniProtKB=G3QT15 G3QT15 PZP PTHR11412:SF92 MACROGLOBULIN / COMPLEMENT PREGNANCY ZONE PROTEIN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 response to stress#GO:0006950;inflammatory response#GO:0006954;response to stimulus#GO:0050896;defense response#GO:0006952 catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000003826.3|UniProtKB=A0A2I2YE76 A0A2I2YE76 TBC1D7 PTHR13530:SF3 TBC1 DOMAIN FAMILY MEMBER 7 TBC1 DOMAIN FAMILY MEMBER 7 binding#GO:0005488;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of TOR signaling#GO:0032006;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000010369.3|UniProtKB=G3R4B8 G3R4B8 RNF26 PTHR22696:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF26 E3 UBIQUITIN-PROTEIN LIGASE RNF26 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005771.3|UniProtKB=G3S9C9 G3S9C9 TCP11L1 PTHR12832:SF15 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11-LIKE PROTEIN 1 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000008242.3|UniProtKB=G3QYW2 G3QYW2 ZNF577 PTHR24404:SF34 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 649 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000005209.3|UniProtKB=G3QR71 G3QR71 SRRM1 PTHR23148:SF0 SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000007438.4|UniProtKB=G3QWV5 G3QWV5 NEGR1 PTHR42757:SF6 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED NEURONAL GROWTH REGULATOR 1 heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell-cell adhesion#GO:0098609;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;cell adhesion#GO:0007155;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803 postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;plasma membrane#GO:0005886;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic density#GO:0014069 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000005993.3|UniProtKB=G3QT55 G3QT55 CILP2 PTHR15031:SF0 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 2 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040519.1|UniProtKB=A0A2I2ZQ42 A0A2I2ZQ42 PTHR23232:SF85 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003785.3|UniProtKB=G3QMH5 G3QMH5 GPR82 PTHR47392:SF1 G-PROTEIN COUPLED RECEPTOR 82-RELATED G PROTEIN-COUPLED RECEPTOR 82-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000043691.1|UniProtKB=A0A2I2Z8Z0 A0A2I2Z8Z0 ZNF813 PTHR24377:SF644 IP01015P-RELATED ZINC FINGER PROTEIN 813 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004900.3|UniProtKB=A0A2I2ZHS2 A0A2I2ZHS2 TRIM40 PTHR24103:SF564 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN LIGASE TRIM40 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000043666.1|UniProtKB=A0A2I2YNF3 A0A2I2YNF3 PTHR23266:SF241 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-30-RELATED antigen binding#GO:0003823;binding#GO:0005488 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000011546.3|UniProtKB=G3R7C5 G3R7C5 LOC109029323 PTHR48615:SF6 LATE CORNIFIED ENVELOPE PROTEIN 1C LATE CORNIFIED ENVELOPE PROTEIN 1A-RELATED GORGO|Ensembl=ENSGGOG00000009563.3|UniProtKB=G3R292 G3R292 MRPS33 PTHR13362:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S33 SMALL RIBOSOMAL SUBUNIT PROTEIN MS33 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000012521.3|UniProtKB=G3R9W2 G3R9W2 LBX1 PTHR24336:SF9 TRANSCRIPTION FACTOR LBX TRANSCRIPTION FACTOR LBX1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000042210.1|UniProtKB=A0A2I2ZQQ5 A0A2I2ZQQ5 LOC101129227 PTHR48553:SF2 SMALL PROLINE-RICH PROTEIN 2E SMALL PROLINE-RICH PROTEIN 2E GORGO|Ensembl=ENSGGOG00000015216.3|UniProtKB=G3RGU1 G3RGU1 PTHR24118:SF65 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER B-RELATED transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012947.3|UniProtKB=G3RAZ8 G3RAZ8 RBM22 PTHR14089:SF6 PRE-MRNA-SPLICING FACTOR RBM22 PRE-MRNA-SPLICING FACTOR RBM22 pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;binding#GO:0005488;snRNA binding#GO:0017069;RNA binding#GO:0003723 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000011990.3|UniProtKB=G3SAJ8 G3SAJ8 MIA2 PTHR23158:SF38 MELANOMA INHIBITORY ACTIVITY-RELATED MELANOMA INHIBITORY ACTIVITY PROTEIN 2 export from cell#GO:0140352;protein localization to extracellular region#GO:0071692;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;secretion by cell#GO:0032940;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;protein secretion#GO:0009306;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000016269.3|UniProtKB=G3R883 G3R883 PTHR24147:SF50 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 36A-RELATED GORGO|Ensembl=ENSGGOG00000004866.3|UniProtKB=A0A2I2YAS8 A0A2I2YAS8 MAEA PTHR12170:SF2 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000013546.3|UniProtKB=G3S122 G3S122 LIPH PTHR11610:SF12 LIPASE LIPASE MEMBER H hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;lipase activity#GO:0016298;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 2-arachidonoylglycerol biosynthesis#P05726>PLA1#P05735 GORGO|Ensembl=ENSGGOG00000040714.1|UniProtKB=A0A2I2Z6R1 A0A2I2Z6R1 CHST6 PTHR10704:SF4 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 6 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 amino sugar metabolic process#GO:0006040;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001249.3|UniProtKB=G3QFZ1 G3QFZ1 ODAD1 PTHR21694:SF35 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 1 cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium movement#GO:0003341;organelle assembly#GO:0070925;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000001075.4|UniProtKB=A0A2I2Y5X7 A0A2I2Y5X7 LOC101145887 PTHR13817:SF190 TITIN CONTACTIN 4 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000008709.4|UniProtKB=G3R039 G3R039 TMEM132D PTHR13388:SF2 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132D cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000003053.3|UniProtKB=G3QKM4 G3QKM4 RRM2B PTHR23409:SF19 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B metabolic process#GO:0008152;cellular process#GO:0009987;biosynthetic process#GO:0009058 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;reductase#PC00198 De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909 GORGO|Ensembl=ENSGGOG00000024585.2|UniProtKB=G3S5F8 G3S5F8 AGBL3 PTHR12756:SF23 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 3 carboxypeptidase activity#GO:0004180;protein binding#GO:0005515;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;binding#GO:0005488;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;catalytic activity#GO:0003824 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000042608.1|UniProtKB=A0A2I2Z655 A0A2I2Z655 PTHR16064:SF4 BTB POZ DOMAIN CONTAINING 7 BTB DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603 GORGO|Ensembl=ENSGGOG00000010370.3|UniProtKB=G3R4C0 G3R4C0 CD14 PTHR10630:SF3 MONOCYTE DIFFERENTIATION ANTIGEN CD14 MONOCYTE DIFFERENTIATION ANTIGEN CD14 lipopolysaccharide binding#GO:0001530;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;lipid binding#GO:0008289 response to lipid#GO:0033993;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;cellular response to lipopolysaccharide#GO:0071222;positive regulation of response to external stimulus#GO:0032103;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;positive regulation of metabolic process#GO:0009893;response to oxygen-containing compound#GO:1901700;response to other organism#GO:0051707;toll-like receptor 4 signaling pathway#GO:0034142;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;cellular response to molecule of bacterial origin#GO:0071219;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;response to external stimulus#GO:0009605;regulation of response to stress#GO:0080134;positive regulation of cytokine production#GO:0001819;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;response to bacterium#GO:0009617;regulation of response to external stimulus#GO:0032101;cellular response to lipid#GO:0071396;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;activation of immune response#GO:0002253;signal transduction#GO:0007165;immune response-activating signaling pathway#GO:0002757;response to lipopolysaccharide#GO:0032496;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;cellular response to biotic stimulus#GO:0071216;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776 membrane microdomain#GO:0098857;signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;membrane raft#GO:0045121;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>CD14#P01373 GORGO|Ensembl=ENSGGOG00000007106.3|UniProtKB=G3QW11 G3QW11 RASSF1 PTHR22738:SF12 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 1 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012252.3|UniProtKB=G3SF16 G3SF16 HAGH PTHR11935:SF80 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE, MITOCHONDRIAL catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002266.3|UniProtKB=G3QIL7 G3QIL7 MS4A4A PTHR23320:SF177 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000037445.1|UniProtKB=A0A2I2ZMB8 A0A2I2ZMB8 PTHR24075:SF13 SEC63 DOMAIN-CONTAINING U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013170.3|UniProtKB=A0A2I2YEM8 A0A2I2YEM8 PTHR23067:SF6 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385C intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000005702.3|UniProtKB=G3S599 G3S599 CFAP410 PTHR18849:SF0 LEUCINE RICH REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410 GORGO|Ensembl=ENSGGOG00000041811.1|UniProtKB=A0A2I2ZLQ5 A0A2I2ZLQ5 XXYLT1 PTHR46612:SF1 XYLOSIDE XYLOSYLTRANSFERASE 1 XYLOSIDE XYLOSYLTRANSFERASE 1 glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000024764.2|UniProtKB=A0A2I2YV97 A0A2I2YV97 GORASP1 PTHR12893:SF2 GOLGI REASSEMBLY STACKING PROTEIN GRASP GOLGI REASSEMBLY-STACKING PROTEIN 1 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000008679.3|UniProtKB=G3R020 G3R020 CHL1 PTHR13817:SF136 TITIN NEURAL CELL ADHESION MOLECULE L1-LIKE PROTEIN structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000001721.3|UniProtKB=A0A2I2Z5P7 A0A2I2Z5P7 EIF5B PTHR43381:SF4 TRANSLATION INITIATION FACTOR IF-2-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 5B translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000001663.3|UniProtKB=G3QH19 G3QH19 IL23A PTHR15947:SF0 SGRF INTERLEUKIN-23 SUBUNIT ALPHA cytokine#PC00083;interleukin superfamily#PC00128;intercellular signal molecule#PC00207 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000022609.2|UniProtKB=A0A2I2ZQ62 A0A2I2ZQ62 ZNF688 PTHR23232:SF69 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 688 double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002519.3|UniProtKB=G3QJ95 G3QJ95 DLAT PTHR23151:SF94 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790 oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227 acetyltransferase#PC00038;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000039266.1|UniProtKB=G3R404 G3R404 ATF5 PTHR13044:SF3 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-5 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000042444.1|UniProtKB=A0A2I2YK05 A0A2I2YK05 PTHR10031:SF58 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE LIPID-BINDING PROTEIN ATP synthase#PC00002;transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000025687.2|UniProtKB=G3S4T9 G3S4T9 GIMAP8 PTHR10903:SF73 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 8 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000013111.3|UniProtKB=A0A2I2YPR6 A0A2I2YPR6 PTHR11652:SF44 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008718.3|UniProtKB=G3R056 G3R056 ASAP1 PTHR45854:SF2 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;positive regulation of cellular process#GO:0048522;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cilium organization#GO:0044782;organelle assembly#GO:0070925;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789 cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Integrin signalling pathway#P00034>ASAP1#P00909 GORGO|Ensembl=ENSGGOG00000026234.2|UniProtKB=G3RP57 G3RP57 RNF19A PTHR11685:SF111 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF19A ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000037456.1|UniProtKB=A0A2I2YAD9 A0A2I2YAD9 REEP5 PTHR12300:SF93 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 5 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000024006.2|UniProtKB=A0A2I2Z7P4 A0A2I2Z7P4 PTHR17550:SF5 E3 UBIQUITIN-PROTEIN LIGASE TTC3 E3 UBIQUITIN-PROTEIN LIGASE TTC3 catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000041599.1|UniProtKB=A0A2I2YPZ3 A0A2I2YPZ3 HSPA13 PTHR19375:SF169 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 13 ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072;Hsp70 family chaperone#PC00027 GORGO|Ensembl=ENSGGOG00000012903.3|UniProtKB=G3RAV4 G3RAV4 P2RY2 PTHR24231:SF17 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 2 G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000042574.1|UniProtKB=A0A2I2Y828 A0A2I2Y828 PTHR39231:SF4 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP25 SIN3A ASSOCIATED PROTEIN 25 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000006766.3|UniProtKB=G3S184 G3S184 SLC25A33 PTHR45829:SF5 MITOCHONDRIAL CARRIER PROTEIN RIM2 SOLUTE CARRIER FAMILY 25 MEMBER 33 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000012462.3|UniProtKB=G3R9R4 G3R9R4 LOC101144055 PTHR21633:SF14 IQ MOTIF CONTAINING F IQ DOMAIN-CONTAINING PROTEIN F1 protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 sexual reproduction#GO:0019953;spermatid development#GO:0007286;regulation of microtubule-based process#GO:0032886;multicellular organismal reproductive process#GO:0048609;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;developmental process#GO:0032502;spermatogenesis#GO:0007283;positive regulation of locomotion#GO:0040017;cell maturation#GO:0048469;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of reproductive process#GO:2000241;developmental maturation#GO:0021700;male gamete generation#GO:0048232;spermatid differentiation#GO:0048515;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;regulation of microtubule-based movement#GO:0060632;cell differentiation#GO:0030154;gamete generation#GO:0007276;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;sperm capacitation#GO:0048240 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669 GORGO|Ensembl=ENSGGOG00000012002.3|UniProtKB=G3RY02 G3RY02 SLC2A11 PTHR23503:SF22 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 11 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000000846.3|UniProtKB=G3QEX7 G3QEX7 SESTD1 PTHR46607:SF1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;phospholipid binding#GO:0005543 GORGO|Ensembl=ENSGGOG00000002692.3|UniProtKB=G3QJQ4 G3QJQ4 GRHL1 PTHR11037:SF16 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 1 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013057.3|UniProtKB=G3RB96 G3RB96 PTP4A2 PTHR23339:SF65 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 2 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000008200.3|UniProtKB=G3R297 G3R297 ASGR1 PTHR22802:SF470 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR 1 molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013716.3|UniProtKB=A0A2I2YUE0 A0A2I2YUE0 ATP5PD PTHR12700:SF17 ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT D, MITOCHONDRIAL channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;nucleoside phosphate biosynthetic process#GO:1901293;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;organelle membrane#GO:0031090;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000009722.3|UniProtKB=G3R2N7 G3R2N7 MYL4 PTHR23048:SF1 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 4 isomerase activity#GO:0016853;structural molecule activity#GO:0005198;cytoskeletal motor activity#GO:0003774;actin monomer binding#GO:0003785;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;protein binding#GO:0005515;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544 muscle system process#GO:0003012;heart process#GO:0003015;striated muscle contraction#GO:0006941;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;cardiac muscle contraction#GO:0060048;muscle contraction#GO:0006936;circulatory system process#GO:0003013;heart contraction#GO:0060047;system process#GO:0003008 protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;A band#GO:0031672;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000039316.1|UniProtKB=A0A2I2Z4J5 A0A2I2Z4J5 LOC101127305 PTHR48553:SF3 SMALL PROLINE-RICH PROTEIN 2E SMALL PROLINE-RICH PROTEIN 2D GORGO|Ensembl=ENSGGOG00000022313.2|UniProtKB=A0A2I2YQM9 A0A2I2YQM9 PHF20L1 PTHR15856:SF26 PHD FINGER PROTEIN 20-RELATED PHD FINGER PROTEIN 20-LIKE PROTEIN 1 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 NSL complex#GO:0044545;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785 GORGO|Ensembl=ENSGGOG00000011944.3|UniProtKB=G3R8E2 G3R8E2 PTHR24100:SF108 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 8 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000014340.3|UniProtKB=G3REJ5 G3REJ5 DUSP26 PTHR45682:SF8 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 26 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000001645.3|UniProtKB=G3QH05 G3QH05 ZSWIM7 PTHR28498:SF1 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000002331.3|UniProtKB=G3S8K4 G3S8K4 RARB PTHR24085:SF5 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR ALPHA transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulatory region nucleic acid binding#GO:0001067 response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to peptide hormone#GO:0043434;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000007722.3|UniProtKB=G3QXL5 G3QXL5 AKT3 PTHR24351:SF199 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to oxygen-containing compound#GO:1901700;response to hormone#GO:0009725;response to endogenous stimulus#GO:0009719;response to peptide hormone#GO:0043434;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000026738.2|UniProtKB=G3RUD4 G3RUD4 MMP10 PTHR10201:SF270 MATRIX METALLOPROTEINASE STROMELYSIN-2 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000011646.3|UniProtKB=G3R7P0 G3R7P0 BAIAP3 PTHR45999:SF1 UNC-13-4A, ISOFORM B BAI1-ASSOCIATED PROTEIN 3 protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;positive regulation of synaptic transmission#GO:0050806;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of neurotransmitter secretion#GO:0046928;positive regulation of cell communication#GO:0010647;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;trans-Golgi network membrane#GO:0032588;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;late endosome membrane#GO:0031902;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003212.3|UniProtKB=A0A2I2YV46 A0A2I2YV46 STOML2 PTHR43327:SF10 STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL transporter#PC00227 GORGO|Ensembl=ENSGGOG00000021992.2|UniProtKB=G3S334 G3S334 PTHR22747:SF36 NUCLEOPLASMIN NUCLEOPHOSMIN nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515;RNA binding#GO:0003723 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;regulation of DNA-templated transcription#GO:0006355;nuclear transport#GO:0051169;nuclear export#GO:0051168;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;ribosomal large subunit export from nucleus#GO:0000055;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;establishment of organelle localization#GO:0051656;regulation of cell cycle#GO:0051726;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular localization#GO:0051641;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cell cycle process#GO:0010564;positive regulation of transcription by RNA polymerase II#GO:0045944;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840 intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000043915.1|UniProtKB=A0A2I2ZB00 A0A2I2ZB00 CDC42EP3 PTHR15344:SF3 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 3 enzyme binding#GO:0019899;binding#GO:0005488;small GTPase binding#GO:0031267;protein binding#GO:0005515 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;Rho protein signal transduction#GO:0007266;positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of supramolecular fiber organization#GO:1902903;cellular response to stimulus#GO:0051716;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of cell projection organization#GO:0031346;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cell projection assembly#GO:0060491 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001680.3|UniProtKB=G3RZF0 G3RZF0 TFCP2L1 PTHR11037:SF18 TRANSCRIPTION FACTOR CP2 TRANSCRIPTION FACTOR CP2-LIKE PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008317.3|UniProtKB=G3QZ40 G3QZ40 MAP3K15 PTHR11584:SF363 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 15 MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;p38MAPK cascade#GO:0038066;intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000004321.3|UniProtKB=A0A2I2YK50 A0A2I2YK50 SMC1A PTHR18937:SF170 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1A DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000013077.3|UniProtKB=G3RBB8 G3RBB8 KANSL2 PTHR13453:SF1 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 GORGO|Ensembl=ENSGGOG00000000654.3|UniProtKB=A0A2I2Z1Q4 A0A2I2Z1Q4 PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-N7 METHYLTRANSFERASE ACTIVATING SUBUNIT-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;RNA binding#GO:0003723;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000009131.3|UniProtKB=G3SIW7 G3SIW7 ETFB PTHR21294:SF8 ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000036763.1|UniProtKB=A0A2I2Y6X9 A0A2I2Y6X9 CFAP144P1 PTHR33865:SF1 PROTEIN FAM183B PROTEIN CFAP144P1 cilium#GO:0005929;ciliary base#GO:0097546;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000013002.3|UniProtKB=G3RB41 G3RB41 PTHR13703:SF28 SMAD SMAD FAMILY MEMBER 6 sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;sequence-specific double-stranded DNA binding#GO:1990837;molecular function regulator activity#GO:0098772;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 cellular response to growth factor stimulus#GO:0071363;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 TGF-beta signaling pathway#P00052>I-SMAD#G01548;TGF-beta signaling pathway#P00052>I-Smads#P01289 GORGO|Ensembl=ENSGGOG00000043131.1|UniProtKB=A0A2I2YHF9 A0A2I2YHF9 PTHR31905:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 PROTEIN MIX23 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000023277.2|UniProtKB=G3SDG5 G3SDG5 FNTA PTHR11129:SF5 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000015965.3|UniProtKB=G3RIR9 G3RIR9 SLC12A2 PTHR11827:SF58 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 2 symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 sodium ion transport#GO:0006814;monoatomic anion transport#GO:0006820;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;chloride transport#GO:0006821;establishment of localization#GO:0051234 apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;membrane#GO:0016020;cell body#GO:0044297;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000010149.3|UniProtKB=G3R3S1 G3R3S1 TATDN2 PTHR46363:SF1 DEOXYRIBONUCLEASE TATDN2-RELATED 3'-5' RNA NUCLEASE TATDN2 endodeoxyribonuclease#PC00093 GORGO|Ensembl=ENSGGOG00000044165.1|UniProtKB=A0A2I2ZUQ9 A0A2I2ZUQ9 MILR1 PTHR11481:SF58 IMMUNOGLOBULIN FC RECEPTOR ALLERGIN-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;immune response#GO:0006955;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000010839.3|UniProtKB=G3R5J7 G3R5J7 PRMT5 PTHR10738:SF0 PROTEIN ARGININE N-METHYLTRANSFERASE 5 PROTEIN ARGININE N-METHYLTRANSFERASE 5 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023286.2|UniProtKB=G3S7I7 G3S7I7 ANTXR2 PTHR16059:SF13 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 cell adhesion molecule#PC00069 GORGO|Gene=TAS2R20|UniProtKB=Q646A0 Q646A0 TAS2R20 PTHR11394:SF173 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 20 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004392.3|UniProtKB=G3QP27 G3QP27 HDLBP PTHR10627:SF34 SCP160 VIGILIN binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000039336.1|UniProtKB=A0A2I2Z0T8 A0A2I2Z0T8 CALHM5 PTHR32261:SF8 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 5 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000041473.1|UniProtKB=A0A2I2YXV0 A0A2I2YXV0 PTHR14564:SF2 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT MIC26 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrion organization#GO:0007005;membrane organization#GO:0061024 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000001146.3|UniProtKB=G3S959 G3S959 ABCB1 PTHR24222:SF93 ABC TRANSPORTER B FAMILY ABC-TYPE XENOBIOTIC TRANSPORTER transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000039969.1|UniProtKB=A0A2I2Z4T2 A0A2I2Z4T2 PTHR24184:SF27 SI:CH211-189E2.2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10 plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000010989.3|UniProtKB=A0A2I2YY32 A0A2I2YY32 BMPR2 PTHR23255:SF63 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-2 transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;molecular transducer activity#GO:0060089;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transforming growth factor beta receptor activity#GO:0005024;transferase activity#GO:0016740;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;vasculature development#GO:0001944 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740 GORGO|Ensembl=ENSGGOG00000011711.3|UniProtKB=G3R7S5 G3R7S5 PTHR11537:SF23 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 2 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249 metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054;axon terminus#GO:0043679;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;main axon#GO:0044304;presynapse#GO:0098793;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;transmembrane transporter complex#GO:1902495;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;synapse#GO:0045202;cellular anatomical structure#GO:0110165;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection terminus#GO:0044306 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000007622.3|UniProtKB=P60047 P60047 PABPC5 PTHR24012:SF682 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 5 mRNA 3'-UTR binding#GO:0003730;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;poly(A) binding#GO:0008143;mRNA binding#GO:0003729 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014583.3|UniProtKB=G3RF66 G3RF66 SLC9A4 PTHR10110:SF103 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 4 antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000002893.3|UniProtKB=G3QK77 G3QK77 DAPL1 PTHR13177:SF2 DEATH-ASSOCIATED PROTEIN 1 DEATH-ASSOCIATED PROTEIN-LIKE 1 binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;negative regulation of gene expression#GO:0010629;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;negative regulation of translation#GO:0017148;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;negative regulation of catabolic process#GO:0009895;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of autophagy#GO:0010507;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 GORGO|Ensembl=ENSGGOG00000008453.3|UniProtKB=G3QZG1 G3QZG1 UMODL1 PTHR14002:SF22 ENDOGLIN/TGF-BETA RECEPTOR TYPE III UROMODULIN-LIKE 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001299.3|UniProtKB=G3QG31 G3QG31 SPINK7 PTHR47499:SF1 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 inflammatory response#GO:0006954;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;defense response#GO:0006952;regulation of proteolysis#GO:0030162;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000010381.3|UniProtKB=G3R4C6 G3R4C6 TNFRSF13B PTHR15511:SF2 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026873.2|UniProtKB=G3RSE5 G3RSE5 OSTC PTHR13160:SF9 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000023601.2|UniProtKB=G3SEG7 G3SEG7 RNF150 PTHR22765:SF42 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING FINGER PROTEIN 150 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000451.3|UniProtKB=G3QDW3 G3QDW3 TFAP4 PTHR15741:SF27 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR AP-4 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000027882.2|UniProtKB=G3RYK0 G3RYK0 FREY1 PTHR37872:SF1 SIMILAR TO RIKEN CDNA 1700029I15 PROTEIN FREY 1 cell-cell recognition#GO:0009988;multicellular organismal reproductive process#GO:0048609;sperm-egg recognition#GO:0035036;cell recognition#GO:0008037;sexual reproduction#GO:0019953;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;fertilization#GO:0009566;single fertilization#GO:0007338;cellular process#GO:0009987;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000042661.1|UniProtKB=A0A2I2Y3S2 A0A2I2Y3S2 PTHR24103:SF677 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 61-RELATED ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;biological regulation#GO:0065007;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002329.3|UniProtKB=G3QIS5 G3QIS5 GPSM3 PTHR47617:SF1 G-PROTEIN SIGNALING MODULATOR 3 G PROTEIN-SIGNALING MODULATOR 3 regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;positive regulation of defense response#GO:0031349;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of inflammatory response#GO:0050729;positive regulation of response to external stimulus#GO:0032103 GORGO|Ensembl=ENSGGOG00000007844.3|UniProtKB=A0A2I2ZSJ2 A0A2I2ZSJ2 MACO1 PTHR47464:SF2 MACOILIN MACOILIN GORGO|Ensembl=ENSGGOG00000007461.3|UniProtKB=G3QWY2 G3QWY2 TMPRSS3 PTHR24253:SF86 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 3 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 proteolysis#GO:0006508;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;sensory perception of sound#GO:0007605;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;system process#GO:0003008;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000010527.3|UniProtKB=G3R4R0 G3R4R0 NCR1 PTHR11738:SF14 MHC CLASS I NK CELL RECEPTOR NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000012163.3|UniProtKB=G3S681 G3S681 TRPT1 PTHR12684:SF2 PUTATIVE PHOSPHOTRANSFERASE TRNA 2'-PHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA splicing#GO:0008380;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA biosynthetic process#GO:0032774 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002398.3|UniProtKB=A0A2I2YU68 A0A2I2YU68 GNAO1 PTHR10218:SF363 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(O) SUBUNIT ALPHA G protein-coupled receptor binding#GO:0001664;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;neuropeptide receptor binding#GO:0071855;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;GTPase activity#GO:0003924;protein binding#GO:0005515;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737 heterotrimeric G-protein#PC00117;G-protein#PC00020 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Enkephalin release#P05913>G-Protein (i)#P05974;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Opioid prodynorphin pathway#P05916>G-protein#P06002;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Endogenous cannabinoid signaling#P05730>Galpha#P05751;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Goalpha#P00729 GORGO|Ensembl=ENSGGOG00000002288.3|UniProtKB=G3RWS1 G3RWS1 BUB1B PTHR14030:SF29 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 BETA protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 organelle organization#GO:0006996;negative regulation of sister chromatid segregation#GO:0033046;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;cellular process#GO:0009987;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;meiotic sister chromatid cohesion#GO:0051177;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;chromosome organization#GO:0051276;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;negative regulation of chromosome organization#GO:2001251;cell communication#GO:0007154;sister chromatid cohesion#GO:0007062;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047 membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;kinetochore#GO:0000776 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000006316.3|UniProtKB=G3S4V3 G3S4V3 TENT4B PTHR23092:SF51 POLY(A) RNA POLYMERASE TERMINAL NUCLEOTIDYLTRANSFERASE 4B adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000034821.2|UniProtKB=G3SKT5 G3SKT5 CBLL2 PTHR13480:SF1 E3 UBIQUITIN-PROTEIN LIGASE HAKAI-RELATED E3 UBIQUITIN-PROTEIN LIGASE CBLL2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005364.3|UniProtKB=G3QRJ5 G3QRJ5 PTHR11142:SF33 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE SYNTHASE-LIKE 1 catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;pseudouridine synthesis#GO:0001522;mRNA modification#GO:0016556;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 lyase#PC00144 GORGO|Ensembl=ENSGGOG00000003383.3|UniProtKB=G3QLH3 G3QLH3 CD164 PTHR11337:SF12 MUCIN/PORIMIN SIALOMUCIN CORE PROTEIN 24 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000004779.3|UniProtKB=A0A2I2YYV7 A0A2I2YYV7 STMN3 PTHR10104:SF17 STATHMIN STATHMIN-3 protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 neurogenesis#GO:0022008;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular developmental process#GO:0048869;developmental process#GO:0032502;protein depolymerization#GO:0051261;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;microtubule polymerization or depolymerization#GO:0031109;system development#GO:0048731;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;regulation of microtubule-based process#GO:0032886;protein-containing complex disassembly#GO:0032984;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;neuron development#GO:0048666;cellular component disassembly#GO:0022411;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000002165.3|UniProtKB=G3QIC6 G3QIC6 REST PTHR24403:SF102 ZINC FINGER PROTEIN RE1-SILENCING TRANSCRIPTION FACTOR DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of neuron differentiation#GO:0045664;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cell differentiation#GO:0045595;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000001327.3|UniProtKB=G3QG59 G3QG59 SLC35C1 PTHR11132:SF255 SOLUTE CARRIER FAMILY 35 GDP-FUCOSE TRANSPORTER 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804 nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleotide-sugar transmembrane transport#GO:0015780;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000037042.1|UniProtKB=A0A2I2YIZ6 A0A2I2YIZ6 TMEM182 PTHR32012:SF0 TRANSMEMBRANE PROTEIN 182-RELATED TRANSMEMBRANE PROTEIN 182 GORGO|Ensembl=ENSGGOG00000003530.3|UniProtKB=G3S2C5 G3S2C5 PCSK9 PTHR43806:SF60 PEPTIDASE S8 PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 9 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000008404.3|UniProtKB=A0A2I2YB32 A0A2I2YB32 DCAF12 PTHR19860:SF10 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 12 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000015660.3|UniProtKB=A0A2I2YTW7 A0A2I2YTW7 CCDC106 PTHR16477:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 106 COILED-COIL DOMAIN-CONTAINING PROTEIN 106 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000001479.3|UniProtKB=G3RRF1 G3RRF1 UPF2 PTHR12839:SF7 NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2 REGULATOR OF NONSENSE TRANSCRIPTS 2 nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000037848.1|UniProtKB=A0A2I2ZU44 A0A2I2ZU44 PTHR23073:SF77 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 4 ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502 protease#PC00190 GORGO|Ensembl=ENSGGOG00000005122.3|UniProtKB=G3QQY9 G3QQY9 ZNF620 PTHR23226:SF441 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 621 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000017180.3|UniProtKB=G3RLV5 G3RLV5 ZBTB43 PTHR46105:SF15 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 43 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000037486.1|UniProtKB=A0A2I2Z669 A0A2I2Z669 PPIF PTHR11071:SF408 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to stress#GO:0006950;regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;response to chemical#GO:0042221;regulation of membrane permeability#GO:0090559;cellular response to oxidative stress#GO:0034599;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;mitochondrial protein-containing complex#GO:0098798;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000001924.3|UniProtKB=G3QHR1 G3QHR1 G2E3 PTHR12420:SF37 PHD FINGER PROTEIN G2_M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000014502.3|UniProtKB=G3REZ4 G3REZ4 FAM193B PTHR15109:SF3 AGAP004327-PA PROTEIN FAM193B nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000023559.2|UniProtKB=G3RS51 G3RS51 GATA1 PTHR10071:SF190 TRANSCRIPTION FACTOR GATA FAMILY MEMBER ERYTHROID TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015808.3|UniProtKB=G3SGJ0 G3SGJ0 BRCA2 PTHR11289:SF0 BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2 BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;double-strand break repair#GO:0006302;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000011360.3|UniProtKB=G3R6V2 G3R6V2 LGALS1 PTHR11346:SF97 GALECTIN GALECTIN-1 extracellular matrix binding#GO:0050840;carbohydrate binding#GO:0030246;protein binding#GO:0005515;laminin binding#GO:0043236;binding#GO:0005488;oligosaccharide binding#GO:0070492 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000014304.3|UniProtKB=A0A2I2YQZ7 A0A2I2YQZ7 GPM6B PTHR11683:SF10 MYELIN PROTEOLIPID NEURONAL MEMBRANE GLYCOPROTEIN M6-B structural molecule activity#GO:0005198 cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;oligodendrocyte differentiation#GO:0048709;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;axon development#GO:0061564;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;gliogenesis#GO:0042063;neurogenesis#GO:0022008;myelination#GO:0042552;developmental process#GO:0032502;neuron differentiation#GO:0030182 myelin sheath#GO:0043209;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000037552.1|UniProtKB=A0A2I2YUG9 A0A2I2YUG9 PTHR11668:SF472 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE PP1-BETA CATALYTIC SUBUNIT catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 regulation of metabolic process#GO:0019222;circadian regulation of gene expression#GO:0032922;regulation of macromolecule biosynthetic process#GO:0010556;regulation of circadian rhythm#GO:0042752;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;rhythmic process#GO:0048511;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;circadian rhythm#GO:0007623 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 GORGO|Ensembl=ENSGGOG00000010982.3|UniProtKB=G3R5W9 G3R5W9 SPX PTHR28590:SF1 SPEXIN SPEXIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;neuropeptide hormone activity#GO:0005184 regulation of smooth muscle contraction#GO:0006940;regulation of muscle contraction#GO:0006937;regulation of system process#GO:0044057;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000016220.3|UniProtKB=G3RJD8 G3RJD8 MKX PTHR11211:SF3 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX HOMEOBOX PROTEIN MOHAWK RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 muscle organ development#GO:0007517;developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000004548.2|UniProtKB=G3QPF9 G3QPF9 PRR9 PTHR48427:SF1 PROLINE-RICH PROTEIN 9 PROLINE-RICH PROTEIN 9 GORGO|Ensembl=ENSGGOG00000012906.3|UniProtKB=G3RAW5 G3RAW5 GAA PTHR22762:SF92 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE alpha-glucosidase activity#GO:0090599;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 generation of precursor metabolites and energy#GO:0006091;lytic vacuole organization#GO:0080171;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;lysosome organization#GO:0007040;cellular process#GO:0009987;glycogen catabolic process#GO:0005980;organelle organization#GO:0006996;energy reserve metabolic process#GO:0006112;vacuole organization#GO:0007033;carbohydrate catabolic process#GO:0016052;polysaccharide catabolic process#GO:0000272;glycogen metabolic process#GO:0005977;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976 glucosidase#PC00108 GORGO|Ensembl=ENSGGOG00000008142.3|UniProtKB=G3QYL1 G3QYL1 LOC101134919 PTHR23262:SF186 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 1-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000043172.1|UniProtKB=G3QI37 G3QI37 PTHR11711:SF329 ADP RIBOSYLATION FACTOR-RELATED ARL5A nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to Golgi apparatus#GO:0034067;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657 Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000003349.3|UniProtKB=G3QLD6 G3QLD6 LOC101141801 PTHR10366:SF364 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3 BETA-HYDROXYSTEROID DEHYDROGENASE_DELTA 5--4-ISOMERASE TYPE 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 regulation of hormone levels#GO:0010817;cellular process#GO:0009987;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;biological regulation#GO:0065007;lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;regulation of biological quality#GO:0065008;steroid biosynthetic process#GO:0006694 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144;dehydratase#PC00091;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>3beta-Hydroxysteroid dehydrogenase#P02833 GORGO|Ensembl=ENSGGOG00000040733.1|UniProtKB=A0A2I2ZD38 A0A2I2ZD38 LOC101124732 PTHR23232:SF146 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002091.3|UniProtKB=G3QI57 G3QI57 JOSD1 PTHR13291:SF1 JOSEPHIN 1, 2 JOSEPHIN-1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 cysteine protease#PC00081;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006524.3|UniProtKB=G3QUI2 G3QUI2 RSAD1 PTHR13932:SF5 COPROPORPHYRINIGEN III OXIDASE RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488 porphyrin-containing compound biosynthetic process#GO:0006779;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;cellular process#GO:0009987;porphyrin-containing compound metabolic process#GO:0006778 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidase#PC00175 Heme biosynthesis#P02746>Coproporphyrinogen oxidase (oxygen independent)#P02970 GORGO|Ensembl=ENSGGOG00000044054.1|UniProtKB=A0A2I2Y4J7 A0A2I2Y4J7 LOC109024612 PTHR11954:SF41 D-DOPACHROME DECARBOXYLASE D-DOPACHROME TAUTOMERASE LIKE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;lyase#PC00144;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000679.3|UniProtKB=G3QEH4 G3QEH4 ACTR8 PTHR11937:SF13 ACTIN ACTIN-RELATED PROTEIN 8 structural molecule activity#GO:0005198;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleic acid binding#GO:0003676 double-strand break repair#GO:0006302;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000034824.2|UniProtKB=G3SKE8 G3SKE8 NAALAD2 PTHR10404:SF38 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE 2 carboxypeptidase activity#GO:0004180;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000025828.2|UniProtKB=A0A2I2ZR56 A0A2I2ZR56 PTHR48002:SF81 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4S1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014607.3|UniProtKB=G3RF87 G3RF87 SAV1 PTHR47522:SF2 SALVADOR FAMILY WW DOMAIN-CONTAINING PROTEIN 1 PROTEIN SALVADOR HOMOLOG 1 hippo signaling#GO:0035329;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of cell population proliferation#GO:0008285;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;intracellular signal transduction#GO:0035556;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000023289.2|UniProtKB=A0A2I2Z8G9 A0A2I2Z8G9 SEM1 PTHR16771:SF11 26 PROTEASOME COMPLEX SUBUNIT DSS1 26S PROTEASOME COMPLEX SUBUNIT SEM1 DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;proteasome complex#GO:0000502;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular protein-containing complex#GO:0140535 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000005121.3|UniProtKB=G3QQY5 G3QQY5 ZMAT2 PTHR45986:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 2 ZINC FINGER MATRIN-TYPE PROTEIN 2 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 Sm-like protein family complex#GO:0120114;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000011989.3|UniProtKB=G3R8J7 G3R8J7 ARHGEF15 PTHR12845:SF7 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 15 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of actin filament-based process#GO:0032970;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000005662.3|UniProtKB=G3QSB6 G3QSB6 ASNS PTHR11772:SF36 ASPARAGINE SYNTHETASE ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING] ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ligase#PC00142 Asparagine and aspartate biosynthesis#P02730>Asparagine synthetase#P02853 GORGO|Ensembl=ENSGGOG00000001877.3|UniProtKB=G3QHL6 G3QHL6 IRAK2 PTHR24419:SF2 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-LIKE 2 histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;cell cycle#GO:0007049;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cytokine-mediated signaling pathway#GO:0019221;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000001524.3|UniProtKB=G3QGP7 G3QGP7 HECTD3 PTHR46654:SF1 E3 UBIQUITIN-PROTEIN LIGASE HECTD3 E3 UBIQUITIN-PROTEIN LIGASE HECTD3 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000008155.3|UniProtKB=G3QYN5 G3QYN5 HHIPL1 PTHR19328:SF32 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 1 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000016247.3|UniProtKB=A0A2I2ZGX4 A0A2I2ZGX4 ROGDI PTHR13618:SF1 LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1 PROTEIN ROGDI HOMOLOG cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000023890.2|UniProtKB=G3S316 G3S316 SFT2D2 PTHR23137:SF1 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2B GORGO|Ensembl=ENSGGOG00000008492.3|UniProtKB=G3QZK0 G3QZK0 PTHR21556:SF2 TRESLIN TRESLIN binding#GO:0005488;chromatin binding#GO:0003682 regulation of DNA-templated DNA replication initiation#GO:0030174;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of DNA metabolic process#GO:0051052;mitotic DNA replication checkpoint signaling#GO:0033314;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of DNA replication#GO:0006275;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;regulation of metabolic process#GO:0019222;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of primary metabolic process#GO:0080090;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated DNA replication#GO:0090329;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015527.3|UniProtKB=G3RHM5 G3RHM5 ZBTB10 PTHR24414:SF27 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 10 DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000028517.2|UniProtKB=G3RXN8 G3RXN8 TMEM244 PTHR12952:SF1 SYS1 TRANSMEMBRANE PROTEIN 244-RELATED membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000003235.3|UniProtKB=G3QL38 G3QL38 DRC12 PTHR28656:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 153 DYNEIN REGULATORY COMPLEX PROTEIN 12 GORGO|Ensembl=ENSGGOG00000025406.2|UniProtKB=G3RME2 G3RME2 PABIR3 PTHR22227:SF3 FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1 PABIR FAMILY MEMBER 1 protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein serine/threonine phosphatase inhibitor activity#GO:0004865;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864 regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;biological regulation#GO:0065007;positive regulation of protein metabolic process#GO:0051247;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000003018.3|UniProtKB=G3QKI8 G3QKI8 LOC101129101 PTHR26450:SF112 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51I2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000041432.1|UniProtKB=A0A2I2YVS4 A0A2I2YVS4 PTHR31911:SF3 PROTEIN FAM133 PROTEIN FAM133B RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007105.3|UniProtKB=G3SHZ5 G3SHZ5 CATIP PTHR15505:SF3 RIIA DOMAIN-CONTAINING PROTEIN 1 CILIOGENESIS-ASSOCIATED TTC17-INTERACTING PROTEIN cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cilium organization#GO:0044782 GORGO|Ensembl=ENSGGOG00000017171.3|UniProtKB=G3RLU7 G3RLU7 PATZ1 PTHR24379:SF75 KRAB AND ZINC FINGER DOMAIN-CONTAINING VASCULAR ENDOTHELIAL ZINC FINGER 1 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000006500.3|UniProtKB=G3SAB9 G3SAB9 KDM8 PTHR12461:SF106 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND ARGINYL-HYDROXYLASE JMJD5 histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;chromatin binding#GO:0003682;binding#GO:0005488;protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000017102.3|UniProtKB=A0A2I2ZUI1 A0A2I2ZUI1 GSTCD PTHR13369:SF4 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN response to stress#GO:0006950;inflammatory response#GO:0006954;response to stimulus#GO:0050896;defense response#GO:0006952 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000043805.1|UniProtKB=P02024 P02024 HBB PTHR11442:SF42 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT BETA molecular carrier activity#GO:0140104;binding#GO:0005488;heme binding#GO:0020037;protein binding#GO:0005515;tetrapyrrole binding#GO:0046906 hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;cellular process#GO:0009987;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;cell development#GO:0048468;homeostatic process#GO:0042592;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;localization#GO:0051179;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219;globin#PC00107 GORGO|Ensembl=ENSGGOG00000001217.3|UniProtKB=G3QFW6 G3QFW6 ZFP62 PTHR24404:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 835 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004227.3|UniProtKB=G3QNM6 G3QNM6 LOC101128649 PTHR26453:SF293 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008338.3|UniProtKB=A0A2I2ZMS6 A0A2I2ZMS6 VPS33B PTHR11679:SF92 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33B macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;lytic vacuole#GO:0000323;vesicle tethering complex#GO:0099023;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000015933.3|UniProtKB=G3RIM8 G3RIM8 NEURL2 PTHR12429:SF8 NEURALIZED NEURALIZED-LIKE PROTEIN 2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;supramolecular fiber organization#GO:0097435;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 GORGO|Ensembl=ENSGGOG00000011507.3|UniProtKB=G3R793 G3R793 PTHR22792:SF158 LUPUS LA PROTEIN-RELATED LUPUS LA PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008565.3|UniProtKB=G3QZQ9 G3QZQ9 GSG1 PTHR10671:SF43 EPITHELIAL MEMBRANE PROTEIN-RELATED GERM CELL-SPECIFIC GENE 1 PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000022345.3|UniProtKB=G3S9H3 G3S9H3 MLXIP PTHR15741:SF23 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MLX-INTERACTING PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000002740.3|UniProtKB=G3QJU6 G3QJU6 RPAIN PTHR31742:SF1 RPA-INTERACTING PROTEIN RPAIN RPA-INTERACTING PROTEIN protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000005309.3|UniProtKB=G3QRE6 G3QRE6 HOXA13 PTHR45804:SF3 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-A13 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000042617.1|UniProtKB=A0A2I2YCP2 A0A2I2YCP2 PARD6G PTHR14102:SF3 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG GAMMA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell-cell junction organization#GO:0045216;establishment or maintenance of cell polarity#GO:0007163;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;microtubule cytoskeleton organization#GO:0000226;cell-cell junction maintenance#GO:0045217;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell junction organization#GO:0034330 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;apical plasma membrane#GO:0016324;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;apical part of cell#GO:0045177;protein kinase complex#GO:1902911;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000007028.3|UniProtKB=G3QVV0 G3QVV0 KHSRP PTHR10288:SF101 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 2 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of mRNA stability#GO:0043488;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010628.3|UniProtKB=G3R4Z4 G3R4Z4 GMPPB PTHR22572:SF15 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE CATALYTIC SUBUNIT BETA nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;organophosphate metabolic process#GO:0019637;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 GORGO|Ensembl=ENSGGOG00000027896.2|UniProtKB=A0A2I2Z2F3 A0A2I2Z2F3 PTHR15680:SF21 RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010820.3|UniProtKB=G3R5I0 G3R5I0 RPGRIP1 PTHR14240:SF3 RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN 1 cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515 ciliary transition zone#GO:0035869;cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002583.3|UniProtKB=G3QJF0 G3QJF0 VSX2 PTHR24323:SF6 CEH-10 HOMEODOMAIN-CONTAINING HOMOLOG VISUAL SYSTEM HOMEOBOX 2 nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000024728.2|UniProtKB=G3SBE5 G3SBE5 PTHR14211:SF9 GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2 RIBOSOME BIOGENESIS PROTEIN NOP53 nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;binding#GO:0005488;RNA binding#GO:0003723 protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;RNA metabolic process#GO:0016070;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000000312.3|UniProtKB=A0A2I2Z030 A0A2I2Z030 IQCA1L PTHR14690:SF6 IQ MOTIF CONTAINING WITH AAA DOMAIN 1 DYNEIN REGULATORY COMPLEX SUBUNIT LIKE-11 GORGO|Ensembl=ENSGGOG00000007841.3|UniProtKB=G3QXV3 G3QXV3 PISD PTHR10067:SF6 PHOSPHATIDYLSERINE DECARBOXYLASE PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000013216.3|UniProtKB=G3RST4 G3RST4 PTHR15739:SF2 ZINC FINGER PROTEIN PROTEIN ZNF365 organelle organization#GO:0006996;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of cellular component organization#GO:0051128;regulation of double-strand break repair via homologous recombination#GO:0010569;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of cellular response to stress#GO:0080135;regulation of DNA recombination#GO:0000018;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;regulation of cell projection organization#GO:0031344;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of double-strand break repair#GO:2000779;telomere organization#GO:0032200 GORGO|Ensembl=ENSGGOG00000014512.3|UniProtKB=G3RF12 G3RF12 ARFGAP3 PTHR45686:SF1 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 3 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000040434.1|UniProtKB=G3RTD6 G3RTD6 PTHR23411:SF34 TAPASIN T CELL RECEPTOR BETA CONSTANT 1 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;signaling receptor complex#GO:0043235 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000001208.3|UniProtKB=G3QFV8 G3QFV8 ATG4B PTHR22624:SF39 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4B hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;proteolysis#GO:0006508;organelle assembly#GO:0070925;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;autophagosome organization#GO:1905037;autophagy#GO:0006914;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagosome assembly#GO:0000045 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000010661.3|UniProtKB=A0A2I2YLI8 A0A2I2YLI8 BCAR1 PTHR10654:SF15 CAS SCAFFOLDING PROTEIN BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 1 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;cytoplasm#GO:0005737;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 Integrin signalling pathway#P00034>p130CAS#P00908;CCKR signaling map#P06959>CAS#P07180 GORGO|Ensembl=ENSGGOG00000004645.3|UniProtKB=G3QPQ0 G3QPQ0 CCNJL PTHR10177:SF63 CYCLINS CYCLIN-J-LIKE PROTEIN cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000013841.3|UniProtKB=A0A2I2YFT3 A0A2I2YFT3 TSPAN7 PTHR19282:SF257 TETRASPANIN TETRASPANIN-7 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005719.3|UniProtKB=G3QSG2 G3QSG2 C1QTNF2 PTHR15427:SF28 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 2 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027203.2|UniProtKB=G3RMT5 G3RMT5 RPS3A PTHR11830:SF28 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000016300.3|UniProtKB=A0A2I2Y780 A0A2I2Y780 ZNF727 PTHR23226:SF313 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 93 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012356.3|UniProtKB=G3R9H6 G3R9H6 SHF PTHR15127:SF28 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN F binding#GO:0005488;protein binding#GO:0005515 GORGO|Ensembl=ENSGGOG00000012218.3|UniProtKB=G3R963 G3R963 PLCB3 PTHR10336:SF11 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-3 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;calmodulin binding#GO:0005516;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein binding#GO:0005515;lipase activity#GO:0016298;binding#GO:0005488 monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;signal transduction#GO:0007165;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;metabolic process#GO:0008152;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;organophosphate metabolic process#GO:0019637;establishment of localization#GO:0051234;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;transport#GO:0006810;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;hydrolase#PC00121 Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;Endothelin signaling pathway#P00019>PLCbeta#P00591;Endogenous cannabinoid signaling#P05730>PLC#P05746;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;Wnt signaling pathway#P00057>Phospholipase C#P01443;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 GORGO|Ensembl=ENSGGOG00000009715.3|UniProtKB=G3R2N1 G3R2N1 MOB2 PTHR22599:SF21 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 2 kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000007427.3|UniProtKB=G3RWL4 G3RWL4 KYAT1 PTHR43807:SF14 FI04487P KYNURENINE--OXOGLUTARATE TRANSAMINASE 1 transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000015287.3|UniProtKB=G3RGZ8 G3RGZ8 RPA2 PTHR13989:SF54 REPLICATION PROTEIN A-RELATED REPLICATION PROTEIN A 32 KDA SUBUNIT sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676 response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;replication fork#GO:0005657;replisome#GO:0030894;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;protein-DNA complex#GO:0032993;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;chromosome, telomeric region#GO:0000781;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DNA replication#P00017>RPA#P00537 GORGO|Ensembl=ENSGGOG00000038460.1|UniProtKB=A0A2I2ZFD4 A0A2I2ZFD4 SSMEM1 PTHR31822:SF1 SERINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 SERINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000001411.3|UniProtKB=A0A2I2YEB8 A0A2I2YEB8 METTL1 PTHR23417:SF24 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510 intracellular anatomical structure#GO:0005622;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000028492.2|UniProtKB=G3S915 G3S915 DGCR2 PTHR15256:SF6 INTEGRAL MEMBRANE PROTEIN DGCR2/IDD INTEGRAL MEMBRANE PROTEIN DGCR2_IDD cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000002932.3|UniProtKB=G3QKB2 G3QKB2 RPL13A PTHR11545:SF30 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of translation#GO:0017148;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012498.3|UniProtKB=G3R9U9 G3R9U9 TTI1 PTHR18460:SF3 TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER TELO2-INTERACTING PROTEIN 1 HOMOLOG cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002311.3|UniProtKB=G3QIQ9 G3QIQ9 FLOT1 PTHR13806:SF47 FLOTILLIN-RELATED FLOTILLIN-1 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of receptor-mediated endocytosis#GO:0048259;positive regulation of endocytosis#GO:0045807;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of endocytosis#GO:0030100;positive regulation of cellular component organization#GO:0051130;regulation of localization#GO:0032879;regulation of transport#GO:0051049 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane raft#GO:0044853;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;membrane raft#GO:0045121;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane microdomain#GO:0098857;cell periphery#GO:0071944;caveola#GO:0005901;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590 GORGO|Ensembl=ENSGGOG00000004271.3|UniProtKB=G3QNS2 G3QNS2 DRP2 PTHR12268:SF16 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN-RELATED PROTEIN 2 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000024267.2|UniProtKB=G3SCV8 G3SCV8 EGLN1 PTHR12907:SF4 EGL NINE HOMOLOG-RELATED EGL NINE HOMOLOG 1 catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;iron ion binding#GO:0005506;catalytic activity#GO:0003824;ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;metal ion binding#GO:0046872;dioxygenase activity#GO:0051213;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914 response to stress#GO:0006950;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;response to hypoxia#GO:0001666;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 GORGO|Ensembl=ENSGGOG00000000682.3|UniProtKB=G3QEH7 G3QEH7 OPRK1 PTHR24229:SF1 NEUROPEPTIDES RECEPTOR KAPPA-TYPE OPIOID RECEPTOR G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide binding#GO:0042277;neuropeptide binding#GO:0042923 system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;sensory perception of pain#GO:0019233;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Opioid prodynorphin pathway#P05916>Kappa Receptor#P05998;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 GORGO|Ensembl=ENSGGOG00000002387.3|UniProtKB=G3QIX8 G3QIX8 NIPAL2 PTHR12570:SF16 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED NIPA-LIKE PROTEIN 2 transport#GO:0006810;magnesium ion transport#GO:0015693;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000007325.3|UniProtKB=G3QWL0 G3QWL0 RAPSN PTHR46574:SF1 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;synaptic signaling#GO:0099536;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, cholinergic#GO:0007271;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;neuromuscular junction#GO:0031594;synapse#GO:0045202;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008262.3|UniProtKB=G3QYY1 G3QYY1 PTHR11559:SF416 CARBOXYLESTERASE CARBOXYLESTERASE 3 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000006133.3|UniProtKB=G3QTI1 G3QTI1 DSC2 PTHR24025:SF0 DESMOGLEIN FAMILY MEMBER DESMOCOLLIN-2 calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000023337.2|UniProtKB=G3S1Y8 G3S1Y8 IL2 PTHR48487:SF1 INTERLEUKIN-2 INTERLEUKIN-2 cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;interleukin-2-mediated signaling pathway#GO:0038110;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Interleukin signaling pathway#P00036>Interleukin#P00970;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 GORGO|Ensembl=ENSGGOG00000006336.3|UniProtKB=G3QU10 G3QU10 DRG2 PTHR43127:SF2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014072.3|UniProtKB=G3RDV7 G3RDV7 GJA10 PTHR11984:SF9 CONNEXIN GAP JUNCTION ALPHA-10 PROTEIN passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161 gap junction#PC00105;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000015426.3|UniProtKB=G3RHC8 G3RHC8 POLR2I PTHR11239:SF1 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;transcription initiation at RNA polymerase II promoter#GO:0006367;DNA-templated transcription elongation#GO:0006354;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;response to stimulus#GO:0050896;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 GORGO|Ensembl=ENSGGOG00000006356.3|UniProtKB=A0A2I2ZJG8 A0A2I2ZJG8 SLC36A1 PTHR22950:SF188 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 1 carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;neutral L-amino acid transmembrane transporter activity#GO:0015175;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;proton transmembrane transporter activity#GO:0015078;glycine transmembrane transporter activity#GO:0015187;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;alanine transport#GO:0032328;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transmembrane transport#GO:1905039;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;glycine transport#GO:0015816 vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 GORGO|Ensembl=ENSGGOG00000009896.3|UniProtKB=A0A2I2YPR2 A0A2I2YPR2 CPNE7 PTHR10857:SF6 COPINE COPINE-7 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to chemical#GO:0042221;response to stimulus#GO:0050896;response to calcium ion#GO:0051592;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to metal ion#GO:0010038;cellular response to chemical stimulus#GO:0070887 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000006575.3|UniProtKB=G3SD79 G3SD79 CNKSR1 PTHR12844:SF10 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>CNKSR1#P07029 GORGO|Ensembl=ENSGGOG00000005449.3|UniProtKB=G3QRS2 G3QRS2 RIPPLY1 PTHR16770:SF5 PROTEIN RIPPLY-LIKE PROTEIN RIPPLY1 embryo development#GO:0009790;embryonic pattern specification#GO:0009880;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000001238.3|UniProtKB=G3QFY3 G3QFY3 CPM PTHR11532:SF84 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE M metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 GORGO|Ensembl=ENSGGOG00000024098.2|UniProtKB=A0A2I2ZCZ6 A0A2I2ZCZ6 YWHAG PTHR18860:SF22 14-3-3 PROTEIN 14-3-3 PROTEIN GAMMA enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;Parkinson disease#P00049>14-3-3#P01238 GORGO|Ensembl=ENSGGOG00000023543.2|UniProtKB=A0A2I2YVC5 A0A2I2YVC5 LRWD1 PTHR24370:SF10 OPTICIN LEUCINE-RICH REPEAT AND WD REPEAT-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000005765.3|UniProtKB=G3QSK5 G3QSK5 SFMBT1 PTHR12247:SF77 POLYCOMB GROUP PROTEIN SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000001495.3|UniProtKB=G3S3Y0 G3S3Y0 SGK1 PTHR24351:SF184 RIBOSOMAL PROTEIN S6 KINASE SERINE_THREONINE-PROTEIN KINASE SGK1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006511.3|UniProtKB=G3QUH0 G3QUH0 KRT40 PTHR23239:SF90 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 40 structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000042973.1|UniProtKB=A0A2I2YXV3 A0A2I2YXV3 WWOX PTHR24320:SF304 RETINOL DEHYDROGENASE WW DOMAIN-CONTAINING OXIDOREDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 cellular response to transforming growth factor beta stimulus#GO:0071560;response to transforming growth factor beta#GO:0071559;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000002666.3|UniProtKB=A0A2I2ZB74 A0A2I2ZB74 PLXDC1 PTHR13055:SF10 TUMOR ENDOTHELIAL MARKER 7 RELATED PLEXIN DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000009389.3|UniProtKB=G3SDJ7 G3SDJ7 SLC28A1 PTHR10590:SF16 SODIUM/NUCLEOSIDE COTRANSPORTER SODIUM_NUCLEOSIDE COTRANSPORTER 1 symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate derivative transmembrane transporter activity#GO:1901505;solute:sodium symporter activity#GO:0015370;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;nucleoside transmembrane transporter activity#GO:0005337;solute:monoatomic cation symporter activity#GO:0015294 nucleobase-containing compound transport#GO:0015931;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001471.3|UniProtKB=A0A2I2YXX4 A0A2I2YXX4 NCR2 PTHR16423:SF7 TREM-LIKE TRANSCRIPT PROTEIN NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 GORGO|Ensembl=ENSGGOG00000001842.3|UniProtKB=G3QHJ1 G3QHJ1 ULK4 PTHR46240:SF1 SER/THR PROTEIN KINASE ULK4 INACTIVE SERINE_THREONINE-PROTEIN KINASE ULK4 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000013863.3|UniProtKB=G3SJT2 G3SJT2 CDK3 PTHR24056:SF462 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 3 protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;signal transduction#GO:0007165;biological regulation#GO:0065007;mitotic cell cycle process#GO:1903047;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cell cycle#GO:0007049;signaling#GO:0023052;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;mitotic cell cycle phase transition#GO:0044772;cell communication#GO:0007154 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000034992.2|UniProtKB=A0A2I2ZA87 A0A2I2ZA87 MAD1L1 PTHR23168:SF0 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular component organization#GO:0016043;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;metaphase chromosome alignment#GO:0051310;negative regulation of cell cycle#GO:0045786;mitotic spindle assembly checkpoint signaling#GO:0007094;attachment of spindle microtubules to kinetochore#GO:0008608;chromosome localization#GO:0050000;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;organelle localization#GO:0051640;negative regulation of chromosome organization#GO:2001251;intracellular signal transduction#GO:0035556;organelle fission#GO:0048285;cell communication#GO:0007154;localization#GO:0051179;mitotic metaphase chromosome alignment#GO:0007080;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic cell cycle#GO:0007346;mitotic sister chromatid segregation#GO:0000070;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;nuclear division#GO:0000280;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;sister chromatid segregation#GO:0000819;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of chromosome segregation#GO:0051985;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;regulation of mitotic sister chromatid segregation#GO:0033047;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;negative regulation of organelle organization#GO:0010639;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;chromosome#GO:0005694;organelle envelope#GO:0031967;kinetochore#GO:0000776 GORGO|Ensembl=ENSGGOG00000002601.3|UniProtKB=G3QJG7 G3QJG7 PTHR10794:SF60 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000002476.3|UniProtKB=A0A2I2YB84 A0A2I2YB84 SIGLEC5 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;organic acid binding#GO:0043177 cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000016572.3|UniProtKB=G3RKA3 G3RKA3 C18H16orf90 PTHR37334:SF1 RGD1561796 SIMILAR TO HUMAN CHROMOSOME 16 OPEN READING FRAME 90 GORGO|Ensembl=ENSGGOG00000012653.3|UniProtKB=G3S927 G3S927 LOC101150657 PTHR15087:SF14 PROTEIN NPAT PROTEIN NPAT transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000012838.3|UniProtKB=G3RAP4 G3RAP4 HOXB3 PTHR45664:SF11 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 embryo development#GO:0009790;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;skeletal system development#GO:0001501;regulation of primary metabolic process#GO:0080090;skeletal system morphogenesis#GO:0048705;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000008977.3|UniProtKB=A0A2I2Z4A5 A0A2I2Z4A5 ZNF75D PTHR23226:SF272 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 75D sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000038739.1|UniProtKB=A0A2I2YA94 A0A2I2YA94 IL1RN PTHR10078:SF28 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine binding#GO:0019955;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;molecular function activator activity#GO:0140677;growth factor binding#GO:0019838;protein binding#GO:0005515 inflammatory response#GO:0006954;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;regulation of cell communication#GO:0010646;negative regulation of response to cytokine stimulus#GO:0060761;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;defense response#GO:0006952;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;response to peptide#GO:1901652;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;negative regulation of biological process#GO:0048519;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;negative regulation of cytokine-mediated signaling pathway#GO:0001960;response to lipopolysaccharide#GO:0032496;regulation of cytokine-mediated signaling pathway#GO:0001959;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;regulation of response to cytokine stimulus#GO:0060759;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;negative regulation of signal transduction#GO:0009968;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;response to cytokine#GO:0034097 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;cytokine#PC00083;interleukin superfamily#PC00128 GORGO|Ensembl=ENSGGOG00000041213.1|UniProtKB=A0A2I2Z6V5 A0A2I2Z6V5 SNORC PTHR28453:SF1 PROTEIN SNORC PROTEIN SNORC cell periphery#GO:0071944;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015385.3|UniProtKB=G3RH95 G3RH95 PRICKLE4 PTHR24211:SF35 LIM DOMAIN-CONTAINING PROTEIN PRICKLE PLANAR CELL POLARITY PROTEIN 4 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002620.3|UniProtKB=G3QJI2 G3QJI2 OR2A25 PTHR26453:SF257 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016245.3|UniProtKB=A0A2I2YMY9 A0A2I2YMY9 SPPL3 PTHR12174:SF22 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 3 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi-associated vesicle membrane#GO:0030660;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi-associated vesicle#GO:0005798;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554 aspartic protease#PC00053;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000027588.2|UniProtKB=A0A2I2ZHK0 A0A2I2ZHK0 PIH1D2 PTHR22997:SF6 PIH1 DOMAIN-CONTAINING PROTEIN 1 PIH1 DOMAIN-CONTAINING PROTEIN 2 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 GORGO|Ensembl=ENSGGOG00000015998.3|UniProtKB=G3RIV3 G3RIV3 OPLAH PTHR11365:SF2 5-OXOPROLINASE RELATED 5-OXOPROLINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812 sulfur compound catabolic process#GO:0044273;catabolic process#GO:0009056;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006788.3|UniProtKB=A0A2I2YYM8 A0A2I2YYM8 UNC5D PTHR12582:SF5 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5D molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;cellular process#GO:0009987;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 GORGO|Ensembl=ENSGGOG00000042275.1|UniProtKB=A0A2I2ZVI8 A0A2I2ZVI8 NRXN3 PTHR15036:SF57 PIKACHURIN-LIKE PROTEIN NEUREXIN-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;signaling receptor binding#GO:0005102;binding#GO:0005488 intracellular protein localization#GO:0008104;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;macromolecule localization#GO:0033036;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;postsynaptic specialization organization#GO:0099084;organelle assembly#GO:0070925;protein localization to cell junction#GO:1902414;cognition#GO:0050890;synapse organization#GO:0050808;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;postsynapse organization#GO:0099173;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;signal transduction#GO:0007165;postsynaptic density assembly#GO:0097107;cellular process#GO:0009987;animal gross anatomical part developmental process#GO:0160108;nervous system process#GO:0050877;postsynaptic density organization#GO:0097106;response to stimulus#GO:0050896;synapse assembly#GO:0007416;signaling#GO:0023052;excitatory synapse assembly#GO:1904861;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786;presynaptic active zone membrane#GO:0048787;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000009166.3|UniProtKB=G3R198 G3R198 CCNO PTHR10177:SF401 CYCLINS CYCLIN-O enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000010200.3|UniProtKB=A0A2I2ZVJ5 A0A2I2ZVJ5 ZNF141 PTHR24381:SF439 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 141 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000027305.2|UniProtKB=G3S4Y0 G3S4Y0 PTHR10513:SF19 DEOXYNUCLEOSIDE KINASE DEOXYCYTIDINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;deoxynucleoside kinase activity#GO:0019136;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000001671.3|UniProtKB=G3QH27 G3QH27 SLC22A1 PTHR24064:SF291 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 1 transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;quaternary ammonium group transmembrane transporter activity#GO:0015651;active transmembrane transporter activity#GO:0022804 quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000027381.2|UniProtKB=G3RVJ8 G3RVJ8 CRIP1 PTHR46074:SF3 CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER CYSTEINE-RICH PROTEIN 1 metal ion binding#GO:0046872;cation binding#GO:0043169;zinc ion binding#GO:0008270;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;regulation of gene expression#GO:0010468;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;signaling#GO:0023052;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000015941.3|UniProtKB=G3RIN9 G3RIN9 TIMM21 PTHR13032:SF6 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000024625.2|UniProtKB=G3S3X7 G3S3X7 ALG10 PTHR12989:SF12 ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10 DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE B glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000040736.1|UniProtKB=A0A2I2YBV9 A0A2I2YBV9 PRR23E PTHR31813:SF17 PROLINE-RICH PROTEIN 23B PROLINE-RICH PROTEIN 23E GORGO|Ensembl=ENSGGOG00000006769.3|UniProtKB=A0A2I2Z8J2 A0A2I2Z8J2 IKBKB PTHR22969:SF7 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;response to tumor necrosis factor#GO:0034612;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;cytokine-mediated signaling pathway#GO:0019221;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>IKK#P00313;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871;Interleukin signaling pathway#P00036>Ikk#P00968;Toll receptor signaling pathway#P00054>IKKbeta#P01360;B cell activation#P00010>IKK#P00397;T cell activation#P00053>IKK#P01330;PDGF signaling pathway#P00047>Ikk#P01146 GORGO|Ensembl=ENSGGOG00000008301.3|UniProtKB=A0A2I2Z8J5 A0A2I2Z8J5 C13H9orf85 PTHR22876:SF5 ZGC:101016 CHROMOSOME 9 OPEN READING FRAME 85 GORGO|Ensembl=ENSGGOG00000010986.3|UniProtKB=G3R5X4 G3R5X4 SCO2 PTHR12151:SF2 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER CYTOCHROME C OXIDASE ASSEMBLY FACTOR SCO2 mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108 oxidase#PC00175;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000015244.3|UniProtKB=G3RGW0 G3RGW0 LOC129528877 PTHR48001:SF67 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7G1 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013765.3|UniProtKB=A0A2I2Y4P6 A0A2I2Y4P6 SLA PTHR46037:SF5 PROTEIN ENHANCER OF SEVENLESS 2B SRC-LIKE-ADAPTER growth factor receptor binding#GO:0070851;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;signaling#GO:0023052;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of MAPK cascade#GO:0043408;regulation of intracellular signal transduction#GO:1902531 nuclear protein-containing complex#GO:0140513;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000014067.3|UniProtKB=G3RDV6 G3RDV6 IRX3 PTHR11211:SF14 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-3 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell development#GO:0048468;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000009938.3|UniProtKB=G3R385 G3R385 ZXDC PTHR46179:SF5 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZXDC transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000044075.1|UniProtKB=G3S4D5 G3S4D5 PTHR11593:SF11 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010291.3|UniProtKB=A0A2I2YC30 A0A2I2YC30 SNX13 PTHR22775:SF51 SORTING NEXIN SORTING NEXIN-13 ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;small molecule binding#GO:0036094 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS-PX1#P00706 GORGO|Ensembl=ENSGGOG00000016179.3|UniProtKB=G3RJD1 G3RJD1 MYO15A PTHR22692:SF21 MYOSIN VII, XV MYOSIN XVA actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000005329.3|UniProtKB=G3QRG5 G3QRG5 NTF4 PTHR11589:SF8 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIN-4 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;neuron development#GO:0048666;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of trans-synaptic signaling#GO:0099177;nervous system development#GO:0007399;negative regulation of neuron apoptotic process#GO:0043524;neuron projection development#GO:0031175;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular response to nerve growth factor stimulus#GO:1990090;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;extracellular region#GO:0005576;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;secretory vesicle#GO:0099503 growth factor#PC00112;neurotrophic factor#PC00163 GORGO|Ensembl=ENSGGOG00000008264.2|UniProtKB=G3QYX7 G3QYX7 LOC101133357 PTHR26453:SF215 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10AD1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014720.3|UniProtKB=G3RFJ7 G3RFJ7 SV2B PTHR23511:SF2 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2B intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;regulation of transport#GO:0051049;intracellular calcium ion homeostasis#GO:0006874;regulation of localization#GO:0032879;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;inorganic ion homeostasis#GO:0098771;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;calcium ion homeostasis#GO:0055074;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;modulation of chemical synaptic transmission#GO:0050804;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of cell communication#GO:0010646;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular process#GO:0050794 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular vesicle#GO:0097708 GORGO|Ensembl=ENSGGOG00000015532.3|UniProtKB=A0A2I2ZE16 A0A2I2ZE16 WDR64 PTHR44324:SF2 WD40 REPEAT DOMAIN 95 WD REPEAT-CONTAINING PROTEIN 64 GORGO|Ensembl=ENSGGOG00000010558.3|UniProtKB=G3R2R0 G3R2R0 KLC4 PTHR45783:SF6 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 4 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 GORGO|Ensembl=ENSGGOG00000025379.2|UniProtKB=G3SEN4 G3SEN4 PTHR31453:SF2 TRANSMEMBRANE PROTEIN 236 TRANSMEMBRANE PROTEIN 236 GORGO|Ensembl=ENSGGOG00000002121.3|UniProtKB=G3S665 G3S665 APBB1 PTHR14058:SF5 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 1 peptide binding#GO:0042277;binding#GO:0005488 DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to stress#GO:0033554;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126;Alzheimer disease-amyloid secretase pathway#P00003>Fe65#P00087 GORGO|Ensembl=ENSGGOG00000003139.3|UniProtKB=G3QKV3 G3QKV3 MKS1 PTHR12968:SF4 B9 DOMAIN-CONTAINING TECTONIC-LIKE COMPLEX MEMBER MKS1 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000027581.2|UniProtKB=A0A2I2Y2F1 A0A2I2Y2F1 C1H1orf50 PTHR14553:SF1 UNCHARACTERIZED PROTEIN C1ORF50 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 50 GORGO|Ensembl=ENSGGOG00000003064.3|UniProtKB=G3QKN5 G3QKN5 LLGL1 PTHR10241:SF21 LETHAL 2 GIANT LARVAE PROTEIN LETHAL(2) GIANT LARVAE PROTEIN HOMOLOG 1 cytoskeletal protein binding#GO:0008092;enzyme activator activity#GO:0008047;SNARE binding#GO:0000149;myosin binding#GO:0017022;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function activator activity#GO:0140677;syntaxin binding#GO:0019905;protein binding#GO:0005515;enzyme regulator activity#GO:0030234 vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;regulation of response to stimulus#GO:0048583;transport#GO:0006810;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;establishment of spindle localization#GO:0051293;localization#GO:0051179;cortical actin cytoskeleton organization#GO:0030866;microtubule cytoskeleton organization#GO:0000226;secretion#GO:0046903;localization within membrane#GO:0051668;actin filament-based process#GO:0030029;regulation of Notch signaling pathway#GO:0008593;cortical cytoskeleton organization#GO:0030865;organelle localization#GO:0051640;regulation of cell communication#GO:0010646;Golgi to plasma membrane transport#GO:0006893;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;exocytosis#GO:0006887;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;regulation of establishment or maintenance of cell polarity#GO:0032878;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;secretion by cell#GO:0032940;post-Golgi vesicle-mediated transport#GO:0006892;spindle localization#GO:0051653;cellular localization#GO:0051641;regulation of signaling#GO:0023051;establishment or maintenance of cell polarity#GO:0007163;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular component organization#GO:0016043 cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;membrane#GO:0016020;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000004950.3|UniProtKB=G3QQJ2 G3QQJ2 PTHR12663:SF1 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG B chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000025783.2|UniProtKB=G3S886 G3S886 GLRX2 PTHR46679:SF1 FAMILY NOT NAMED GLUTAREDOXIN-2, MITOCHONDRIAL disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 GORGO|Ensembl=ENSGGOG00000016732.3|UniProtKB=G3RKP6 G3RKP6 PTHR13962:SF24 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORK-HEAD DOMAIN-CONTAINING PROTEIN double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000011189.3|UniProtKB=G3RF53 G3RF53 RNFT1 PTHR15860:SF1 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNFT1 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;regulation of cellular response to stress#GO:0080135;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of ERAD pathway#GO:1904292;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000002259.3|UniProtKB=G3QIL1 G3QIL1 IL2RB PTHR23037:SF30 CYTOKINE RECEPTOR INTERLEUKIN-2 RECEPTOR SUBUNIT BETA growth factor binding#GO:0019838;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;cytokine receptor activity#GO:0004896;coreceptor activity#GO:0015026 response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;interleukin-2-mediated signaling pathway#GO:0038110;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 GORGO|Ensembl=ENSGGOG00000027647.2|UniProtKB=G3SAU8 G3SAU8 ARSD PTHR42693:SF5 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE D hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000027500.2|UniProtKB=G3SF36 G3SF36 NPM3 PTHR22747:SF13 NUCLEOPLASMIN NUCLEOPLASMIN-3 nucleic acid binding#GO:0003676;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682;RNA binding#GO:0003723;protein binding#GO:0005515 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000014907.3|UniProtKB=G3RG19 G3RG19 LAMB2 PTHR10574:SF36 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-2 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;system development#GO:0048731;external encapsulating structure organization#GO:0045229;cell migration#GO:0016477;extracellular matrix assembly#GO:0085029;tissue development#GO:0009888;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;neuron development#GO:0048666;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000015328.3|UniProtKB=G3RH41 G3RH41 HCST PTHR21409:SF1 HEMATOPOIETIC CELL SIGNAL TRANSDUCER HEMATOPOIETIC CELL SIGNAL TRANSDUCER molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000036552.1|UniProtKB=A0A2I2YDM6 A0A2I2YDM6 PTHR23266:SF286 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 7-4-1 antigen binding#GO:0003823;binding#GO:0005488 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000005017.3|UniProtKB=G3QQP7 G3QQP7 EFL1 PTHR42908:SF3 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR-LIKE GTPASE 1 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity#GO:0016787;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational elongation#GO:0006414;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;translation#GO:0006412;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000025228.2|UniProtKB=A0A2I2Z891 A0A2I2Z891 GMFB PTHR11249:SF3 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR BETA binding#GO:0005488;protein-containing complex binding#GO:0044877 negative regulation of cytoskeleton organization#GO:0051494;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of biological process#GO:0048519;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053 cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000025834.2|UniProtKB=G3RP27 G3RP27 CHSY3 PTHR12369:SF40 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000002158.3|UniProtKB=G3S0X9 G3S0X9 NOLC1 PTHR23216:SF2 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 GORGO|Gene=TAS2R60|UniProtKB=Q645Z0 Q645Z0 TAS2R60 PTHR11394:SF32 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 60 transmembrane signaling receptor activity#GO:0004888;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014780.3|UniProtKB=G3RFP9 G3RFP9 TRUB2 PTHR13195:SF0 PSEUDOURIDINE SYNTHASE-RELATED PSEUDOURIDYLATE SYNTHASE TRUB2, MITOCHONDRIAL isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of translation#GO:0045727;macromolecule modification#GO:0043412;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;mRNA modification#GO:0016556;mRNA metabolic process#GO:0016071;RNA modification#GO:0009451;positive regulation of protein metabolic process#GO:0051247;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 lyase#PC00144 GORGO|Ensembl=ENSGGOG00000013304.3|UniProtKB=G3RBW0 G3RBW0 UBE2R2 PTHR24067:SF148 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 R2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000024776.2|UniProtKB=G3RWU1 G3RWU1 LOC101141507 PTHR12396:SF6 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3-LIKE 2-RELATED biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;constitutive heterochromatin formation#GO:0140719;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000013815.3|UniProtKB=G3RD77 G3RD77 GPR6 PTHR22750:SF19 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 6 transmembrane signaling receptor activity#GO:0004888;bioactive lipid receptor activity#GO:0045125;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000001776.3|UniProtKB=A0A2I2YSU7 A0A2I2YSU7 SLC44A1 PTHR12385:SF56 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;nitrogen compound transport#GO:0071705;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024051.2|UniProtKB=G3SH59 G3SH59 LOC101138507 PTHR23425:SF2 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME N4 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016352.4|UniProtKB=G3RJS3 G3RJS3 CEP131 PTHR31540:SF1 CENTROSOMAL PROTEIN OF 131 KDA CENTROSOMAL PROTEIN OF 131 KDA microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;intraciliary transport involved in cilium assembly#GO:0035735;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cilium movement#GO:0003341;microtubule-based transport#GO:0099111;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cellular localization#GO:0051641;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;transport#GO:0006810;spermatogenesis#GO:0007283;developmental process#GO:0032502;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;male gamete generation#GO:0048232;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;intraciliary transport#GO:0042073;cell motility#GO:0048870;microtubule-based movement#GO:0007018 GORGO|Ensembl=ENSGGOG00000005078.3|UniProtKB=G3QQV1 G3QQV1 LOC101152195 PTHR11732:SF529 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER C8 oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016763.3|UniProtKB=G3RKS1 G3RKS1 FAM222B PTHR16070:SF1 PROTEIN FAM222A-RELATED PROTEIN FAM222B GORGO|Ensembl=ENSGGOG00000009777.3|UniProtKB=G3R2T7 G3R2T7 TTC32 PTHR47059:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 32 TETRATRICOPEPTIDE REPEAT PROTEIN 32 GORGO|Ensembl=ENSGGOG00000027755.2|UniProtKB=G3SG28 G3SG28 RSPRY1 PTHR13363:SF6 RING FINGER AND SRY DOMAIN-CONTAINING RING FINGER AND SPRY DOMAIN-CONTAINING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009483.3|UniProtKB=G3R230 G3R230 CPVL PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000010013.3|UniProtKB=A0A2I2Z964 A0A2I2Z964 CORO1B PTHR10856:SF24 CORONIN CORONIN-1B protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cell motility#GO:0048870;cell migration#GO:0016477;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;lamellipodium#GO:0030027;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;actin filament#GO:0005884 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000005350.3|UniProtKB=G3QRI5 G3QRI5 DIABLO PTHR32247:SF3 DIABLO HOMOLOG, MITOCHONDRIAL DIABLO IAP-BINDING MITOCHONDRIAL PROTEIN intracellular signal transduction#GO:0035556;intrinsic apoptotic signaling pathway#GO:0097193;neuron apoptotic process#GO:0051402;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;apoptotic signaling pathway#GO:0097190;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Apoptosis signaling pathway#P00006>Smac/Diablo#P00309 GORGO|Ensembl=ENSGGOG00000004099.4|UniProtKB=A0A2I2Z5K8 A0A2I2Z5K8 PTHR39082:SF1 PHOSPHOLIPASE C-BETA-2-RELATED SCAVENGER RECEPTOR CLASS A MEMBER 3 metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143 GORGO|Ensembl=ENSGGOG00000005201.3|UniProtKB=G3S6M4 G3S6M4 SCUBE1 PTHR24046:SF4 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;smoothened signaling pathway#GO:0007224;muscle cell development#GO:0055001;response to endogenous stimulus#GO:0009719;muscle cell differentiation#GO:0042692;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell development#GO:0048468;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000004209.3|UniProtKB=G3QNK9 G3QNK9 B3GALT5 PTHR11214:SF265 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 5 galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000004006.3|UniProtKB=G3QN27 G3QN27 ADAM30 PTHR11905:SF148 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 30 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 multicellular organismal process#GO:0032501;gonad development#GO:0008406;male gonad development#GO:0008584;sex differentiation#GO:0007548;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;animal organ development#GO:0048513;development of primary male sexual characteristics#GO:0046546;metabolic process#GO:0008152;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;male sex differentiation#GO:0046661;reproductive structure development#GO:0048608;reproductive process#GO:0022414;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;system development#GO:0048731;reproductive system development#GO:0061458;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000011452.3|UniProtKB=G3R745 G3R745 PTHR22619:SF4 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 4 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000012500.3|UniProtKB=G3R9V2 G3R9V2 ABCG4 PTHR48041:SF75 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 4 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857 transport#GO:0006810;chemical homeostasis#GO:0048878;sterol transport#GO:0015918;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;cholesterol efflux#GO:0033344;cellular process#GO:0009987;lipid transport#GO:0006869;lipid localization#GO:0010876;localization#GO:0051179;transmembrane transport#GO:0055085;organic hydroxy compound transport#GO:0015850;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000000989.3|UniProtKB=G3QFA8 G3QFA8 CFAP300 PTHR31078:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000038009.1|UniProtKB=A0A2I2ZYG1 A0A2I2ZYG1 C11H2orf66 PTHR47620:SF1 CHROMOSOME 2 OPEN READING FRAME 66 GENE, 34066-RELATED GORGO|Ensembl=ENSGGOG00000021999.2|UniProtKB=G3SK00 G3SK00 FCER1A PTHR11481:SF12 IMMUNOGLOBULIN FC RECEPTOR HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT ALPHA transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;adaptive immune response#GO:0002250;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000016286.3|UniProtKB=G3RJJ3 G3RJJ3 ABRA PTHR22739:SF20 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED ACTIN-BINDING RHO-ACTIVATING PROTEIN positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of Rho protein signal transduction#GO:0035023;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 contractile muscle fiber#GO:0043292;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000028170.2|UniProtKB=G3S2Z9 G3S2Z9 PRICKLE1 PTHR24211:SF15 LIM DOMAIN-CONTAINING PROTEIN PRICKLE-LIKE PROTEIN 1 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;cellular localization#GO:0051641;neuron development#GO:0048666;protein import into nucleus#GO:0006606;protein transport#GO:0015031;neuron projection development#GO:0031175;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;embryo development#GO:0009790;nervous system development#GO:0007399;intracellular protein transport#GO:0006886;neuron differentiation#GO:0030182;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;anatomical structure formation involved in morphogenesis#GO:0048646;tube morphogenesis#GO:0035239;establishment of cell polarity#GO:0030010;cell motility#GO:0048870;protein localization to organelle#GO:0033365;embryo development ending in birth or egg hatching#GO:0009792;nucleocytoplasmic transport#GO:0006913;anatomical structure development#GO:0048856;localization#GO:0051179;tissue morphogenesis#GO:0048729;nuclear transport#GO:0051169;system development#GO:0048731;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cell migration#GO:0016477;epithelium development#GO:0060429;plasma membrane bounded cell projection organization#GO:0120036;tube development#GO:0035295;intracellular transport#GO:0046907;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;establishment of protein localization to organelle#GO:0072594;neurogenesis#GO:0022008;intracellular protein localization#GO:0008104 cell junction#GO:0030054;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014274.3|UniProtKB=G3REE2 G3REE2 SGCG PTHR12939:SF4 SARCOGLYCAN GAMMA-SARCOGLYCAN animal gross anatomical part developmental process#GO:0160108;circulatory system process#GO:0003013;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;system development#GO:0048731;heart process#GO:0003015;circulatory system development#GO:0072359;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;animal organ development#GO:0048513;heart contraction#GO:0060047;system process#GO:0003008;heart development#GO:0007507;blood circulation#GO:0008015;tissue development#GO:0009888;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;sarcolemma#GO:0042383 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000022614.2|UniProtKB=G3RS82 G3RS82 PTHR23235:SF146 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007094.3|UniProtKB=G3QW03 G3QW03 TAOK1 PTHR47167:SF8 SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN SERINE_THREONINE-PROTEIN KINASE TAO1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000024297.2|UniProtKB=A0A2I2YT02 A0A2I2YT02 PTHR10064:SF21 60S RIBOSOMAL PROTEIN L22 RIBOSOMAL PROTEIN L22 nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005743.3|UniProtKB=G3QSI5 G3QSI5 MYL5 PTHR23049:SF8 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN LIGHT CHAIN 5 cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000010070.3|UniProtKB=G3R3K0 G3R3K0 TRIT1 PTHR11088:SF89 TRNA DIMETHYLALLYLTRANSFERASE TRNA DIMETHYLALLYLTRANSFERASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147 GORGO|Gene=SULT6B1|UniProtKB=Q6WG17 Q6WG17 SULT6B1 PTHR11783:SF55 SULFOTRANSFERASE SULT SULFOTRANSFERASE 6B1 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000000737.3|UniProtKB=G3QEM9 G3QEM9 TANC2 PTHR24166:SF21 ROLLING PEBBLES, ISOFORM B PROTEIN TANC2 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;regulation of cell projection organization#GO:0031344;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse organization#GO:0050807 somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection#GO:0043005;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000023090.2|UniProtKB=G3S307 G3S307 ANGPT1 PTHR19143:SF156 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-1 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;receptor tyrosine kinase binding#GO:0030971 circulatory system development#GO:0072359;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-1#P00248 GORGO|Ensembl=ENSGGOG00000012609.3|UniProtKB=G3RA46 G3RA46 SLC22A23 PTHR24064:SF192 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 23 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000022128.2|UniProtKB=G3RUG3 G3RUG3 PSMB1 PTHR32194:SF2 METALLOPROTEASE TLDD PROTEASOME SUBUNIT BETA TYPE-1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;proteasome complex#GO:0000502 metalloprotease#PC00153 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Gene=PCDH11X|UniProtKB=Q6X862 Q6X862 PCDH11X PTHR24028:SF254 CADHERIN-87A PROTOCADHERIN-11 X-LINKED-RELATED cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000002595.3|UniProtKB=A0A2I2ZK23 A0A2I2ZK23 PTHR43085:SF55 HEXOKINASE FAMILY MEMBER KETOHEXOKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;small molecule metabolic process#GO:0044281;regulation of glycogen biosynthetic process#GO:0005979;monosaccharide metabolic process#GO:0005996;regulation of carbohydrate metabolic process#GO:0006109;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065;transferase#PC00220 Fructose galactose metabolism#P02744>Ketohexokinase#P02963 GORGO|Ensembl=ENSGGOG00000015701.3|UniProtKB=G3RI42 G3RI42 LSS PTHR11764:SF94 TERPENE CYCLASE/MUTASE FAMILY MEMBER LANOSTEROL SYNTHASE isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;secondary alcohol biosynthetic process#GO:1902653;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 lyase#PC00144;cyclase#PC00079 Cholesterol biosynthesis#P00014>Anosterol synthase#P00497 GORGO|Ensembl=ENSGGOG00000011397.3|UniProtKB=G3R6Z3 G3R6Z3 ARHGAP42 PTHR12552:SF3 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 42 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000002688.3|UniProtKB=G3QJP9 G3QJP9 PGC PTHR47966:SF72 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED GASTRICSIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 aspartic protease#PC00053;protease#PC00190 GORGO|Ensembl=ENSGGOG00000006950.3|UniProtKB=G3QVM8 G3QVM8 GSS PTHR11130:SF0 GLUTATHIONE SYNTHETASE GLUTATHIONE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000026221.1|UniProtKB=G3SJB1 G3SJB1 ND6 PTHR11435:SF1 NADH UBIQUINONE OXIDOREDUCTASE SUBUNIT ND6 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000012228.3|UniProtKB=G3R950 G3R950 PTHR46756:SF16 TRANSGELIN GAS2-LIKE PROTEIN 1 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;actin filament organization#GO:0007015;protein localization to microtubule cytoskeleton#GO:0072698;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;supramolecular fiber organization#GO:0097435;regulation of microtubule-based process#GO:0032886;actin filament-based process#GO:0030029;microtubule bundle formation#GO:0001578;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;protein localization to organelle#GO:0033365;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;actin filament bundle#GO:0032432;microtubule end#GO:1990752;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;stress fiber#GO:0001725;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actomyosin#GO:0042641;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000006935.3|UniProtKB=G3QVK9 G3QVK9 PRICKLE2 PTHR24211:SF18 LIM DOMAIN-CONTAINING PROTEIN PRICKLE-LIKE PROTEIN 2 plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;regulation of organelle assembly#GO:1902115;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;regulation of cell junction assembly#GO:1901888;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015596.3|UniProtKB=G3RHT5 G3RHT5 CHRNA2 PTHR18945:SF757 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2 channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;acetylcholine receptor activity#GO:0015464;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594 response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;neuromuscular synaptic transmission#GO:0007274;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;modulation of chemical synaptic transmission#GO:0050804;membrane depolarization#GO:0051899;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;synaptic transmission, cholinergic#GO:0007271;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;establishment of localization#GO:0051234;transport#GO:0006810 synapse#GO:0045202;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 GORGO|Ensembl=ENSGGOG00000014141.3|UniProtKB=G3RE24 G3RE24 DUSP21 PTHR46495:SF3 DUAL SPECIFICITY PROTEIN PHOSPHATASE 21 DUAL SPECIFICITY PROTEIN PHOSPHATASE 21 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000013509.3|UniProtKB=G3RQ50 G3RQ50 UBL4A PTHR46555:SF1 UBIQUITIN-LIKE PROTEIN 4A UBIQUITIN-LIKE PROTEIN 4A GORGO|Ensembl=ENSGGOG00000026121.2|UniProtKB=A0A2I2YZ54 A0A2I2YZ54 LOC101151185 PTHR11363:SF4 60S RIBOSOMAL PROTEIN L3-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL3 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004609.3|UniProtKB=G3QPM1 G3QPM1 NNAT PTHR15285:SF0 NEURONATIN NEURONATIN cell differentiation#GO:0030154;regulation of protein transport#GO:0051223;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of hormone secretion#GO:0046883;positive regulation of signaling#GO:0023056;generation of neurons#GO:0048699;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;cellular process#GO:0009987;regulation of insulin secretion#GO:0050796;regulation of localization#GO:0032879;regulation of transport#GO:0051049;multicellular organism development#GO:0007275;positive regulation of protein secretion#GO:0050714;neuron differentiation#GO:0030182;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of protein secretion#GO:0050708;system development#GO:0048731;regulation of establishment of protein localization#GO:0070201;regulation of secretion#GO:0051046;anatomical structure development#GO:0048856;positive regulation of hormone secretion#GO:0046887;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000004207.3|UniProtKB=G3QNL6 G3QNL6 KIAA1549L PTHR21590:SF3 SEA DOMAIN-CONTAINING PROTEIN UPF0606 PROTEIN KIAA1549L GORGO|Ensembl=ENSGGOG00000011196.3|UniProtKB=G3R6G5 G3R6G5 TCF19 PTHR15464:SF1 TRANSCRIPTION FACTOR 19 TRANSCRIPTION FACTOR 19 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000043294.1|UniProtKB=A0A2I2YF66 A0A2I2YF66 KLHL42 PTHR45972:SF2 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH-LIKE PROTEIN 42 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of microtubule-based process#GO:0032886;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;cellular process#GO:0009987 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463 GORGO|Ensembl=ENSGGOG00000005500.3|UniProtKB=G3QRX1 G3QRX1 BLMH PTHR10363:SF2 BLEOMYCIN HYDROLASE BLEOMYCIN HYDROLASE cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 response to chemical#GO:0042221;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;carboxylic acid catabolic process#GO:0046395;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152;response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to toxic substance#GO:0009636;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000016215.3|UniProtKB=G3RJD6 G3RJD6 CTSO PTHR12411:SF992 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN O endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016938.3|UniProtKB=G3RL91 G3RL91 RTKN2 PTHR21538:SF21 ANILLIN/RHOTEKIN RTKN RHOTEKIN-2 positive regulation of cellular process#GO:0048522;hemopoiesis#GO:0030097;biological regulation#GO:0065007;septin cytoskeleton organization#GO:0032185;developmental process#GO:0032502;cellular developmental process#GO:0048869;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell division#GO:0051301;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;mitotic cell cycle#GO:0000278;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;cortical actin cytoskeleton organization#GO:0030866;actomyosin contractile ring assembly#GO:0000915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;positive regulation of cell population proliferation#GO:0008284;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;cytoskeleton-dependent cytokinesis#GO:0061640;septin ring organization#GO:0031106 cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;actomyosin contractile ring#GO:0005826;contractile ring#GO:0070938;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000005767.3|UniProtKB=G3QSK6 G3QSK6 GOT2 PTHR11879:SF39 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 GORGO|Ensembl=ENSGGOG00000009916.3|UniProtKB=G3R365 G3R365 KLF15 PTHR23235:SF44 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 15 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010359.3|UniProtKB=G3R4B1 G3R4B1 TSG101 PTHR23306:SF17 TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED TUMOR SUSCEPTIBILITY GENE 101 PROTEIN ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 vesicle membrane#GO:0012506;membrane#GO:0016020;ESCRT I complex#GO:0000813;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000013691.3|UniProtKB=G3S836 G3S836 PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3B molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000012210.3|UniProtKB=G3R949 G3R949 SYNJ2 PTHR11200:SF148 INOSITOL 5-PHOSPHATASE POLYPHOSPHATIDYLINOSITOL PHOSPHATASE SYNJ2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle endocytosis#GO:0048488;endocytosis#GO:0006897;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;synapse#GO:0045202;presynapse#GO:0098793;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000012337.3|UniProtKB=G3R9G5 G3R9G5 PLA2G4A PTHR10728:SF13 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;carboxylic ester hydrolase activity#GO:0052689;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094;cation binding#GO:0043169;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623;calcium ion binding#GO:0005509;binding#GO:0005488;lipid binding#GO:0008289;metal ion binding#GO:0046872 metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;lipid metabolic process#GO:0006629;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid catabolic process#GO:0016042;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 phospholipase#PC00186 Oxidative stress response#P00046>cPLA2#P01134;Endothelin signaling pathway#P00019>cPLA2#P00583;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLA2#P00855;VEGF signaling pathway#P00056>cPLA2#P01409;Angiogenesis#P00005>PLA2#P00227;Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;CCKR signaling map#P06959>PLA2#P07086;Angiogenesis#P00005>cPLA2#P00251 GORGO|Ensembl=ENSGGOG00000039092.1|UniProtKB=A0A2I2YVY6 A0A2I2YVY6 ACVR1C PTHR23255:SF58 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1C kinase activity#GO:0016301;activin binding#GO:0048185;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089 multicellular organism development#GO:0007275;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;nervous system development#GO:0007399;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;activin receptor signaling pathway#GO:0032924;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;signaling receptor complex#GO:0043235;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 GORGO|Ensembl=ENSGGOG00000001120.3|UniProtKB=A0A2I2ZKK8 A0A2I2ZKK8 CCDC112 PTHR21549:SF0 MUTATED IN BLADDER CANCER 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 112 GORGO|Ensembl=ENSGGOG00000036387.1|UniProtKB=A0A2I2YTV8 A0A2I2YTV8 PDCL3 PTHR45809:SF4 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 3 protein binding#GO:0005515;growth factor receptor binding#GO:0070851;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 primary metabolic process#GO:0044238;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;biosynthetic process#GO:0009058;tube development#GO:0035295;developmental process#GO:0032502;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;circulatory system development#GO:0072359;protein folding#GO:0006457;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;angiogenesis#GO:0001525;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000011946.3|UniProtKB=G3QXS8 G3QXS8 PNPLA6 PTHR14226:SF26 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 6 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 hydrolase#PC00121;esterase#PC00097 GORGO|Ensembl=ENSGGOG00000003776.3|UniProtKB=G3QMG8 G3QMG8 C1H1orf115 PTHR14680:SF1 SI:DKEY-126G1.9-RELATED REQUIRED FOR DRUG-INDUCED DEATH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000004810.3|UniProtKB=G3S3V5 G3S3V5 PTHR24377:SF800 IP01015P-RELATED ZINC FINGER PROTEIN 701 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000039866.1|UniProtKB=A0A2I2Z379 A0A2I2Z379 PTHR21255:SF53 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 1 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000016949.3|UniProtKB=G3RLA0 G3RLA0 MRPL36 PTHR46909:SF3 39S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL36M protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016623.3|UniProtKB=G3SDS4 G3SDS4 ZNF831 PTHR47166:SF1 ZINC FINGER PROTEIN 831 ZINC FINGER PROTEIN 831 GORGO|Ensembl=ENSGGOG00000007493.4|UniProtKB=A0A2I2ZMI0 A0A2I2ZMI0 PTHR10554:SF3 SYNTROPHIN GAMMA-2-SYNTROPHIN plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037739.1|UniProtKB=A0A2I2Z662 A0A2I2Z662 PTHR24068:SF334 UBIQUITIN-CONJUGATING ENZYME E2 UBC CORE DOMAIN-CONTAINING PROTEIN acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein K63-linked ubiquitination#GO:0070534;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein K11-linked ubiquitination#GO:0070979;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000009552.3|UniProtKB=G3R294 G3R294 PLCH1 PTHR10336:SF51 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ETA-1 hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530 GORGO|Ensembl=ENSGGOG00000006043.3|UniProtKB=G3RZS0 G3RZS0 ZFTA PTHR34589:SF2 SIMILAR TO RIKEN CDNA 2700081O15 ZINC FINGER TRANSLOCATION-ASSOCIATED PROTEIN regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 GORGO|Ensembl=ENSGGOG00000026432.2|UniProtKB=G3SC48 G3SC48 SPC25 PTHR14281:SF0 KINETOCHORE PROTEIN SPC25-RELATED KINETOCHORE PROTEIN SPC25 cell cycle process#GO:0022402;cellular process#GO:0009987;chromosome segregation#GO:0007059;cell cycle#GO:0007049 condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;outer kinetochore#GO:0000940;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000003114.3|UniProtKB=G3QKS9 G3QKS9 RARA PTHR24085:SF8 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription factor binding#GO:0008134;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;nuclear receptor binding#GO:0016922;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of primary metabolic process#GO:0080090;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015698.3|UniProtKB=G3RI32 G3RI32 IPCEF1 PTHR12844:SF45 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CNK3_IPCEF1 FUSION PROTEIN-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;postsynaptic specialization organization#GO:0099084;synapse organization#GO:0050808;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;response to stimulus#GO:0050896;postsynapse organization#GO:0099173;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025242.2|UniProtKB=G3R2D7 G3R2D7 PTHR33667:SF7 SI:DKEY-57N24.6 CILIA AND FLAGELLA ASSOCIATED PROTEIN 92 GORGO|Ensembl=ENSGGOG00000011464.3|UniProtKB=G3R758 G3R758 NLRP1 PTHR46985:SF3 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;signaling receptor activity#GO:0038023;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;molecular function activator activity#GO:0140677;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;enzyme regulator activity#GO:0030234 programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of defense response#GO:0031347;inflammatory response#GO:0006954;regulation of immune response#GO:0050776;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;apoptotic signaling pathway#GO:0097190;regulation of innate immune response#GO:0045088;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;canonical inflammasome complex#GO:0061702;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000001291.3|UniProtKB=A0A2I2ZHN5 A0A2I2ZHN5 GHRHR PTHR45620:SF14 PDF RECEPTOR-LIKE PROTEIN-RELATED GROWTH HORMONE-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;protein binding#GO:0005515;molecular transducer activity#GO:0060089;growth factor binding#GO:0019838;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000098.3|UniProtKB=G3QCZ5 G3QCZ5 ILKAP PTHR13832:SF883 PROTEIN PHOSPHATASE 2C INTEGRIN-LINKED KINASE-ASSOCIATED SERINE_THREONINE PHOSPHATASE 2C hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000005035.3|UniProtKB=G3QQQ9 G3QQQ9 DPCD PTHR31921:SF1 PROTEIN DPCD PROTEIN DPCD protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection assembly#GO:0060491;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000042841.1|UniProtKB=G3RSP4 G3RSP4 LOC129533605 PTHR26453:SF235 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2V2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004710.3|UniProtKB=G3QPW1 G3QPW1 RIPK3 PTHR23257:SF974 SERINE-THREONINE PROTEIN KINASE RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 3 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000027760.2|UniProtKB=A0A2I2Y238 A0A2I2Y238 PTHR23430:SF47 HISTONE H2A HISTONE H2A.Z structural molecule activity#GO:0005198 heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;cellular component assembly#GO:0022607;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000025181.2|UniProtKB=G3S0Y1 G3S0Y1 NPS PTHR36679:SF1 NEUROPEPTIDE S NEUROPEPTIDE S positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051;regulation of membrane potential#GO:0042391;positive regulation of signaling#GO:0023056;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of trans-synaptic signaling#GO:0099177;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000028580.2|UniProtKB=A0A2I2YFT5 A0A2I2YFT5 PTHR48033:SF9 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN TAR DNA-BINDING PROTEIN 43 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008966.3|UniProtKB=G3R0S1 G3R0S1 MGME1 PTHR31340:SF3 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;exonuclease activity#GO:0004527;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity#GO:0003824 GORGO|Ensembl=ENSGGOG00000013041.3|UniProtKB=G3S8X2 G3S8X2 DMAC2 PTHR13318:SF186 PARTNER OF PAIRED, ISOFORM B-RELATED DISTAL MEMBRANE-ARM ASSEMBLY COMPLEX PROTEIN 2 proteasomal protein catabolic process#GO:0010498;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;NADH dehydrogenase complex assembly#GO:0010257;ubiquitin-dependent protein catabolic process#GO:0006511;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000038839.1|UniProtKB=A0A2I2YIY3 A0A2I2YIY3 PTHR23138:SF185 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nuclear export#GO:0051168;nuclear transport#GO:0051169;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;intracellular transport#GO:0046907 organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011781.3|UniProtKB=G3R7Z3 G3R7Z3 ERICH1 PTHR22444:SF1 GLUTAMATE-RICH PROTEIN 1 GLUTAMATE-RICH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000015625.3|UniProtKB=G3RHW4 G3RHW4 HS3ST1 PTHR10605:SF16 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000011675.3|UniProtKB=G3RP58 G3RP58 TRIM54 PTHR24103:SF596 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 54 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000011695.3|UniProtKB=A0A2I2YJ36 A0A2I2YJ36 PLEKHB1 PTHR14309:SF7 EXPRESSED PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY B MEMBER 1 regulation of biological process#GO:0050789;regulation of cell differentiation#GO:0045595;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000004284.4|UniProtKB=G3QNT8 G3QNT8 MAST4 PTHR24356:SF224 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;signal transduction#GO:0007165;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000003849.3|UniProtKB=G3QMP2 G3QMP2 PTPN22 PTHR45983:SF1 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 22 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of cell-cell adhesion#GO:0022408;antigen receptor-mediated signaling pathway#GO:0050851;regulation of response to external stimulus#GO:0032101;regulation of T cell activation#GO:0050863;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;negative regulation of immune system process#GO:0002683;T cell receptor signaling pathway#GO:0050852;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;negative regulation of cell activation#GO:0050866;negative regulation of multicellular organismal process#GO:0051241;cellular response to stimulus#GO:0051716;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of leukocyte cell-cell adhesion#GO:1903038;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;negative regulation of T cell activation#GO:0050868;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000002861.3|UniProtKB=G3QK47 G3QK47 HCK PTHR24418:SF245 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE HCK binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular developmental process#GO:0048869;enzyme-linked receptor protein signaling pathway#GO:0007167 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230 GORGO|Ensembl=ENSGGOG00000008199.3|UniProtKB=A0A2I2YAG5 A0A2I2YAG5 HDDC3 PTHR46246:SF1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000002928.3|UniProtKB=A0A2I2Z877 A0A2I2Z877 TRRAP PTHR11139:SF1 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular response to stress#GO:0033554;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;SAGA complex#GO:0000124;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012415.3|UniProtKB=G3RTN0 G3RTN0 POLR2C PTHR11800:SF2 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;transcription by RNA polymerase II#GO:0006366 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 GORGO|Ensembl=ENSGGOG00000013234.3|UniProtKB=A0A2I2ZSD6 A0A2I2ZSD6 SRP72 PTHR14094:SF9 SIGNAL RECOGNITION PARTICLE 72 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72 ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;nucleic acid binding#GO:0003676;binding#GO:0005488 localization within membrane#GO:0051668;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605 ribonucleoprotein complex#GO:1990904;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000017009.3|UniProtKB=A0A2I2YMT8 A0A2I2YMT8 INTS9 PTHR46094:SF1 INTEGRATOR COMPLEX SUBUNIT 9 INTEGRATOR COMPLEX SUBUNIT 9 snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;integrator complex#GO:0032039 GORGO|Ensembl=ENSGGOG00000016122.3|UniProtKB=G3RJ51 G3RJ51 HCN3 PTHR45689:SF7 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 3 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215 regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transporter complex#GO:1990351;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004571.3|UniProtKB=G3SI20 G3SI20 FCN2 PTHR19143:SF433 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-2 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000006514.3|UniProtKB=G3QUH1 G3QUH1 LOC101132106 PTHR26450:SF89 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52B4 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043919.1|UniProtKB=A0A2I2ZMV1 A0A2I2ZMV1 LOC101126219 PTHR23339:SF55 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 1 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 positive regulation of cell migration#GO:0030335;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Gene=NDUFA6|UniProtKB=Q0MQA4 Q0MQA4 NDUFA6 PTHR12964:SF7 NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000006871.3|UniProtKB=A0A2I2Z5W8 A0A2I2Z5W8 FAM83F PTHR16181:SF32 PROTEIN FAM83A-RELATED PROTEIN FAM83F protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000013040.3|UniProtKB=G3RB81 G3RB81 DPPA3 PTHR31577:SF2 DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 3-RELATED DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 3 chromatin-protein adaptor activity#GO:0140463;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone H3K9me2/3 reader activity#GO:0062072;histone reader activity#GO:0140566 cell division#GO:0051301;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;anatomical structure development#GO:0048856;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;embryo development#GO:0009790;biological regulation#GO:0065007;chromatin organization#GO:0006325;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000003322.3|UniProtKB=G3QLB5 G3QLB5 OTOP3 PTHR21522:SF36 PROTON CHANNEL OTOP PROTON CHANNEL OTOP3 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;protein binding#GO:0005515;binding#GO:0005488;proton channel activity#GO:0015252;identical protein binding#GO:0042802;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002790.4|UniProtKB=G3QJZ8 G3QJZ8 ASCC3 PTHR24075:SF6 SEC63 DOMAIN-CONTAINING ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3 ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000119.3|UniProtKB=G3QD15 G3QD15 RBBP8NL PTHR15107:SF3 RETINOBLASTOMA BINDING PROTEIN 8 RBBP8 N-TERMINAL-LIKE PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684;DNA binding#GO:0003677 DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;double-strand break repair via single-strand annealing#GO:0045002;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000004000.3|UniProtKB=G3QN18 G3QN18 MAGEB18 PTHR11736:SF23 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B18 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012299.3|UniProtKB=G3R9C1 G3R9C1 GABARAPL2 PTHR10969:SF114 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 2 binding#GO:0005488;phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;ubiquitin protein ligase binding#GO:0031625 mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;cellular response to nutrient levels#GO:0031669;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component disassembly#GO:0022411;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;response to starvation#GO:0042594;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716 autophagosome#GO:0005776;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000038148.1|UniProtKB=A0A2I2ZCN6 A0A2I2ZCN6 PTHR23266:SF410 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-46 binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000042749.1|UniProtKB=A0A2I2Z9E7 A0A2I2Z9E7 PTHR13168:SF1 ASSOCIATE OF C-MYC AMY-1 C-MYC-BINDING PROTEIN transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000001140.3|UniProtKB=G3QFP6 G3QFP6 HMGCS1 PTHR43323:SF4 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE HYDROXYMETHYLGLUTARYL-COA SYNTHASE, CYTOPLASMIC acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;acetyl-CoA metabolic process#GO:0006084 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA synthase#P00498 GORGO|Ensembl=ENSGGOG00000001954.3|UniProtKB=G3QHT8 G3QHT8 ABI3 PTHR10460:SF7 ABL INTERACTOR FAMILY MEMBER ABI GENE FAMILY MEMBER 3 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell migration#GO:0016477;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of cell migration#GO:0030334;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;system development#GO:0048731 cell leading edge#GO:0031252;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014506.3|UniProtKB=G3REZ9 G3REZ9 ANGPTL4 PTHR19143:SF256 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 4 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;triglyceride homeostasis#GO:0070328;lipid homeostasis#GO:0055088 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000011535.3|UniProtKB=G3R7B6 G3R7B6 MTERF3 PTHR13068:SF194 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 3, MITOCHONDRIAL mitochondrial ribosome assembly#GO:0061668;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;organelle assembly#GO:0070925;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000001097.3|UniProtKB=G3QFK5 G3QFK5 B9D1 PTHR12968:SF1 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 1 cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000039921.1|UniProtKB=A0A2I2Y3I3 A0A2I2Y3I3 LOC101133280 PTHR23430:SF28 HISTONE H2A HISTONE H2A TYPE 1-C structural molecule activity#GO:0005198 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000024206.2|UniProtKB=A0A2I2Z321 A0A2I2Z321 GPAT2 PTHR12563:SF15 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 2, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid metabolic process#GO:0006638 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000013425.3|UniProtKB=G3RN02 G3RN02 FBXW9 PTHR19855:SF34 WD40 REPEAT PROTEIN 12, 37 F-BOX_WD REPEAT-CONTAINING PROTEIN 9 GORGO|Ensembl=ENSGGOG00000040757.1|UniProtKB=A0A2I2YYC0 A0A2I2YYC0 ZNF441 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 670 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006862.3|UniProtKB=G3QVE9 G3QVE9 NKRF PTHR16148:SF15 NF-KAPPA-B-REPRESSING FACTOR-RELATED NF-KAPPA-B-REPRESSING FACTOR DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;molecular function activator activity#GO:0140677;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000000652.3|UniProtKB=G3QEE9 G3QEE9 MIOS PTHR16453:SF9 WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER GATOR2 COMPLEX PROTEIN MIOS positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;regulation of TORC1 signaling#GO:1903432;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular response to amino acid starvation#GO:0034198;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to nutrient levels#GO:0031667;response to stress#GO:0006950;positive regulation of TORC1 signaling#GO:1904263 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000023508.2|UniProtKB=A0A2I2YPP4 A0A2I2YPP4 PTHR10956:SF49 60S RIBOSOMAL PROTEIN L31 LARGE RIBOSOMAL SUBUNIT PROTEIN EL31 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000489.3|UniProtKB=G3QDZ8 G3QDZ8 DRC3 PTHR45973:SF12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN REGULATORY COMPLEX SUBUNIT 3 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000005320.3|UniProtKB=G3QRF7 G3QRF7 GFI1 PTHR24377:SF708 IP01015P-RELATED ZINC FINGER PROTEIN 586 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016354.3|UniProtKB=A0A2I2YEH8 A0A2I2YEH8 ST3GAL3 PTHR13713:SF37 SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-BETA-1,4-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000013823.3|UniProtKB=G3RD95 G3RD95 FERMT1 PTHR16160:SF12 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 1 signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877 cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013341.3|UniProtKB=G3RBZ6 G3RBZ6 STEAP4 PTHR14239:SF5 DUDULIN-RELATED METALLOREDUCTASE STEAP4 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722;catalytic activity#GO:0003824;ferric-chelate reductase activity#GO:0000293 transition metal ion transport#GO:0000041;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000044000.1|UniProtKB=A0A2I2YFN4 A0A2I2YFN4 PELI2 PTHR12098:SF5 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011008.3|UniProtKB=G3R5Z5 G3R5Z5 GHITM PTHR23291:SF112 BAX INHIBITOR-RELATED GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 mitochondrion organization#GO:0007005;monoatomic cation transmembrane transport#GO:0098655;membrane organization#GO:0061024;monoatomic ion transmembrane transport#GO:0034220;mitochondrial membrane organization#GO:0007006;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;mitochondrial calcium ion transmembrane transport#GO:0006851;calcium ion transport#GO:0006816;cellular component organization or biogenesis#GO:0071840;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;cellular component organization#GO:0016043;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000043336.1|UniProtKB=A0A2I2ZNY2 A0A2I2ZNY2 AGPAT3 PTHR10983:SF9 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GAMMA catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000041932.1|UniProtKB=A0A2I2YQ22 A0A2I2YQ22 EPM2A PTHR46864:SF1 LAFORIN LAFORIN catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000001330.3|UniProtKB=A0A2I2YLI7 A0A2I2YLI7 PPP2R2D PTHR11871:SF6 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B DELTA ISOFORM protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 cytosol#GO:0005829;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 GORGO|Ensembl=ENSGGOG00000011759.3|UniProtKB=G3R7W8 G3R7W8 LIPJ PTHR11005:SF11 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER J catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 lipase#PC00143;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000039927.1|UniProtKB=A0A2I2Z0U4 A0A2I2Z0U4 PTHR10792:SF23 60S RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN EL24-RELATED N-TERMINAL DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000023558.2|UniProtKB=A0A2I2YJH7 A0A2I2YJH7 PTHR14388:SF18 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SUPPRESSOR OF CYTOKINE SIGNALING 6 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000005996.3|UniProtKB=G3QT57 G3QT57 ANGPTL2 PTHR19143:SF24 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000037583.1|UniProtKB=A0A2I2ZL36 A0A2I2ZL36 BCL2L11 PTHR12044:SF9 BCL2 INTERACTING MEDIATOR OF CELL DEATH BCL-2-LIKE PROTEIN 11 response to endoplasmic reticulum stress#GO:0034976;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;programmed cell death#GO:0012501;cell cycle#GO:0007049;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;apoptotic signaling pathway#GO:0097190;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;nuclear division#GO:0000280;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;meiotic cell cycle#GO:0051321;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 Apoptosis signaling pathway#P00006>Bim#P00325 GORGO|Ensembl=ENSGGOG00000011064.3|UniProtKB=G3R655 G3R655 ARHGEF10 PTHR12877:SF14 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 10 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 biological regulation#GO:0065007;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;spindle organization#GO:0007051;chromosome organization#GO:0051276;positive regulation of actin filament bundle assembly#GO:0032233;mitotic cell cycle process#GO:1903047;regulation of actin filament-based process#GO:0032970;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;regulation of supramolecular fiber organization#GO:1902903;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059;mitotic spindle organization#GO:0007052;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;regulation of biological process#GO:0050789;positive regulation of organelle organization#GO:0010638;nuclear division#GO:0000280;positive regulation of cellular component organization#GO:0051130 intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000012091.3|UniProtKB=G3SEX3 G3SEX3 MMD2 PTHR20855:SF107 ADIPOR/PROGESTIN RECEPTOR-RELATED MONOCYTE TO MACROPHAGE DIFFERENTIATION FACTOR 2 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015066.3|UniProtKB=G3RGF7 G3RGF7 GPC5 PTHR10822:SF12 GLYPICAN GLYPICAN-5 regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of protein localization to membrane#GO:1905475;positive regulation of biological process#GO:0048518;cell migration#GO:0016477;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of localization#GO:0032879;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of protein localization#GO:0032880 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002548.3|UniProtKB=G3QJC7 G3QJC7 IQGAP3 PTHR14149:SF10 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP3 binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;calmodulin binding#GO:0005516;enzyme activator activity#GO:0008047;cytoskeletal protein binding#GO:0008092;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;mitotic cell cycle process#GO:1903047;actomyosin contractile ring assembly#GO:0000915;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;mitotic cytokinetic process#GO:1902410;cytoskeleton-dependent cytokinesis#GO:0061640;cortical actin cytoskeleton organization#GO:0030866;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;mitotic cell cycle#GO:0000278;actomyosin structure organization#GO:0031032 cell cortex#GO:0005938;cell periphery#GO:0071944;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000001594.3|UniProtKB=G3RTI5 G3RTI5 DIDO1 PTHR11477:SF13 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN DEATH-INDUCER OBLITERATOR 1 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003538.3|UniProtKB=G3QLV5 G3QLV5 OR2W1 PTHR26453:SF169 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2W1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043829.1|UniProtKB=A0A2I2ZW34 A0A2I2ZW34 CIMIP5 PTHR31909:SF2 CHROMOSOME 20 ORF85 FAMILY MEMBER CILIARY MICROTUBULE INNER PROTEIN 5 GORGO|Ensembl=ENSGGOG00000000369.3|UniProtKB=G3S105 G3S105 PTHR10728:SF22 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 ZETA binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;lipase activity#GO:0016298;small molecule binding#GO:0036094;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;ruffle membrane#GO:0032587;ruffle#GO:0001726;cytosol#GO:0005829;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;cytoplasm#GO:0005737 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000012027.3|UniProtKB=G3RVS8 G3RVS8 NAGK PTHR12862:SF0 BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN N-ACETYL-D-GLUCOSAMINE KINASE carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 GORGO|Ensembl=ENSGGOG00000023489.2|UniProtKB=A0A2I2ZHG3 A0A2I2ZHG3 LOC101128496 PTHR14081:SF3 SPERM-ASSOCIATED ANTIGEN 11A-RELATED-RELATED SPERM-ASSOCIATED ANTIGEN 11A-RELATED GORGO|Ensembl=ENSGGOG00000003020.3|UniProtKB=G3QKJ4 G3QKJ4 PLA1A PTHR11610:SF111 LIPASE PHOSPHOLIPASE A1 MEMBER A hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 2-arachidonoylglycerol biosynthesis#P05726>PLA1#P05735 GORGO|Ensembl=ENSGGOG00000039636.1|UniProtKB=A0A2I2YBK8 A0A2I2YBK8 PTHR12675:SF6 MUSCLEBLIND-LIKE PROTEIN ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 10 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000001893.3|UniProtKB=G3QHN0 G3QHN0 STPG3 PTHR21580:SF25 SHIPPO-1-RELATED PROTEIN STPG3 cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;flagellated sperm motility#GO:0030317;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;cilium movement involved in cell motility#GO:0060294;sperm motility#GO:0097722;cellular process#GO:0009987 cytoskeleton#GO:0005856;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000013253.3|UniProtKB=G3RBR5 G3RBR5 PLAC1 PTHR14380:SF2 PLACENTA-SPECIFIC PROTEIN 1 PLACENTA-SPECIFIC PROTEIN 1 GORGO|Ensembl=ENSGGOG00000025875.2|UniProtKB=G3RWF3 G3RWF3 TSPYL4 PTHR11875:SF33 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010509.3|UniProtKB=G3R4N7 G3R4N7 LOC101136919 PTHR26452:SF704 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AS1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000013973.3|UniProtKB=G3RDM3 G3RDM3 C8A PTHR45742:SF1 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C8 ALPHA CHAIN positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;immune response#GO:0006955;humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 complement component#PC00078 GORGO|Ensembl=ENSGGOG00000004414.3|UniProtKB=G3SIU7 G3SIU7 PHF2 PTHR23123:SF14 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE PHF2 histone modifying activity#GO:0140993;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000001613.3|UniProtKB=G3SHK3 G3SHK3 MAN1B1 PTHR11742:SF55 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007119.3|UniProtKB=G3QW19 G3QW19 RCC1 PTHR45982:SF9 REGULATOR OF CHROMOSOME CONDENSATION REGULATOR OF CHROMOSOME CONDENSATION GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of mitotic spindle organization#GO:0060236;regulation of spindle assembly#GO:0090169;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitotic spindle assembly#GO:1901673;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;regulation of organelle assembly#GO:1902115 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014164.3|UniProtKB=G3RE42 G3RE42 ZNF165 PTHR23226:SF61 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 165 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001697.3|UniProtKB=G3QH52 G3QH52 GPN3 PTHR21231:SF7 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 3 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 G-protein#PC00020;protein-binding activity modulator#PC00095;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000007601.3|UniProtKB=G3QXA2 G3QXA2 SEMA5B PTHR11036:SF39 SEMAPHORIN SEMAPHORIN-5B binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 neuron projection extension#GO:1990138;axonogenesis#GO:0007409;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell projection morphogenesis#GO:0048858;cell growth#GO:0016049;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;growth#GO:0040007;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;axon extension#GO:0048675;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;developmental cell growth#GO:0048588;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;developmental growth#GO:0048589;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;axon guidance#GO:0007411 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000039314.1|UniProtKB=A0A2I2ZV32 A0A2I2ZV32 LOC115932623 PTHR20383:SF10 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 LIKE PROTEIN 1-RELATED hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 mRNA processing#GO:0006397;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000013359.3|UniProtKB=G3RC18 G3RC18 HHIP PTHR19328:SF27 HEDGEHOG-INTERACTING PROTEIN HEDGEHOG-INTERACTING PROTEIN protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000001990.3|UniProtKB=G3QHX3 G3QHX3 ZNF750 PTHR14678:SF1 PROLINE-RICH PROTEIN 35-RELATED ZINC FINGER PROTEIN 750 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;tissue development#GO:0009888;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;epidermis development#GO:0008544;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000022980.2|UniProtKB=A0A2I2ZCV0 A0A2I2ZCV0 RCHY1 PTHR21319:SF53 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 P53 pathway feedback loops 1#P04392>Pirh-2#G04684;P53 pathway feedback loops 1#P04392>Pirh-2#P04538 GORGO|Ensembl=ENSGGOG00000007222.3|UniProtKB=A0A2I2YTY7 A0A2I2YTY7 ASL PTHR43814:SF1 ARGININOSUCCINATE LYASE ARGININOSUCCINATE LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 lyase#PC00144 Arginine biosynthesis#P02728>argininosuccinate lyase#P02841 GORGO|Ensembl=ENSGGOG00000013617.3|UniProtKB=G3S1Q1 G3S1Q1 DBT PTHR43178:SF18 LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED CHAIN ALPHA_KETOACID DEHYDROGENASE COMPLEX LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 transferase#PC00220;acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000002670.3|UniProtKB=G3QJM8 G3QJM8 GRP PTHR16866:SF2 GASTRIN-RELEASING PEPTIDE GASTRIN-RELEASING PEPTIDE regulation of response to stress#GO:0080134;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of response to stimulus#GO:0048584;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;positive regulation of multicellular organismal process#GO:0051240;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000024936.2|UniProtKB=G3SA70 G3SA70 LOC101135314 PTHR26453:SF232 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2A5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002520.3|UniProtKB=G3QJ93 G3QJ93 PTHR48424:SF3 DYNEIN LIGHT CHAIN-RELATED DYNEIN LIGHT CHAIN Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000011486.3|UniProtKB=G3R775 G3R775 CERS2 PTHR12560:SF7 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;ceramide metabolic process#GO:0006672;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002335.3|UniProtKB=G3S8C0 G3S8C0 MIDN PTHR23010:SF1 MIDNOLIN MIDNOLIN membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000016992.3|UniProtKB=G3RLE8 G3RLE8 NPHP4 PTHR31043:SF3 NEPHROCYSTIN-4 NEPHROCYSTIN-4 negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;macromolecule localization#GO:0033036;regulation of canonical Wnt signaling pathway#GO:0060828;intracellular protein localization#GO:0008104;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;protein localization to cilium#GO:0061512;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;localization#GO:0051179;negative regulation of cell communication#GO:0010648;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000002985.3|UniProtKB=G3QKG3 G3QKG3 IL31RA PTHR23036:SF96 CYTOKINE RECEPTOR INTERLEUKIN-31 RECEPTOR SUBUNIT ALPHA cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 response to peptide#GO:1901652;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011387.3|UniProtKB=G3R6Y7 G3R6Y7 ADAMTS7 PTHR13723:SF142 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 7 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000005455.3|UniProtKB=G3QRS9 G3QRS9 DTX2 PTHR12622:SF21 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX2-RELATED ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cell communication#GO:0007154;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;signaling#GO:0023052;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;signal transduction#GO:0007165;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009874.3|UniProtKB=G3R328 G3R328 PTMA PTHR22745:SF14 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 negative regulation of cellular process#GO:0048523;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of apoptotic process#GO:0042981;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of apoptotic process#GO:0043066;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000012295.3|UniProtKB=G3SDP1 G3SDP1 SLC25A30 PTHR45618:SF11 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED KIDNEY MITOCHONDRIAL CARRIER PROTEIN 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012910.3|UniProtKB=G3RAW2 G3RAW2 PTHR24345:SF43 SERINE/THREONINE-PROTEIN KINASE PLK INACTIVE SERINE_THREONINE-PROTEIN KINASE PLK5 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;endomembrane system organization#GO:0010256;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;signaling#GO:0023052;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;regulation of G1/S transition of mitotic cell cycle#GO:2000045;organelle disassembly#GO:1903008;regulation of mitotic cell cycle phase transition#GO:1901990;cellular component disassembly#GO:0022411;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;microtubule cytoskeleton organization involved in mitosis#GO:1902850;Golgi organization#GO:0007030;cellular response to stimulus#GO:0051716;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of cell cycle G1/S phase transition#GO:1902806;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000004077.3|UniProtKB=G3QN90 G3QN90 TMEM138 PTHR13306:SF6 TRANSMEMBRANE PROTEIN 138 TRANSMEMBRANE PROTEIN 138 cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000011691.3|UniProtKB=G3R7R9 G3R7R9 TNKS PTHR24180:SF3 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-1 glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of Wnt signaling pathway#GO:0030177;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;regulation of cellular component organization#GO:0051128;regulation of Wnt signaling pathway#GO:0030111;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of telomere maintenance#GO:0032204;intracellular protein localization#GO:0008104;regulation of chromosome organization#GO:0033044;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;positive regulation of DNA metabolic process#GO:0051054;positive regulation of signal transduction#GO:0009967;localization#GO:0051179 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000002342.3|UniProtKB=G3QIU3 G3QIU3 SMG7 PTHR15696:SF5 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG7 nucleic acid binding#GO:0003676;binding#GO:0005488;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;RNA binding#GO:0003723 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036566.1|UniProtKB=A0A2I2YH75 A0A2I2YH75 SPACA4 PTHR47613:SF1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 4 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 4 cellular process#GO:0009987;single fertilization#GO:0007338;reproductive process#GO:0022414;fertilization#GO:0009566;sexual reproduction#GO:0019953;cell recognition#GO:0008037;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000036835.1|UniProtKB=A0A2I2YT47 A0A2I2YT47 PTHR47507:SF7 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000041258.1|UniProtKB=A0A2I2YXR6 A0A2I2YXR6 TAF10 PTHR21242:SF0 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352 nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;peptidase complex#GO:1905368;catalytic complex#GO:1902494;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003325.3|UniProtKB=G3QLC1 G3QLC1 SPDL1 PTHR32123:SF9 BICD FAMILY-LIKE CARGO ADAPTER PROTEIN SPINDLY binding#GO:0005488 establishment of spindle localization#GO:0051293;mitotic sister chromatid segregation#GO:0000070;macromolecule localization#GO:0033036;protein localization to kinetochore#GO:0034501;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;mitotic cell cycle#GO:0000278;protein localization to organelle#GO:0033365;mitotic metaphase chromosome alignment#GO:0007080;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;localization#GO:0051179;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;organelle localization#GO:0051640;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;establishment of organelle localization#GO:0051656;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;spindle localization#GO:0051653;cellular localization#GO:0051641;establishment or maintenance of cell polarity#GO:0007163;nuclear division#GO:0000280 organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;spindle#GO:0005819;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000023522.2|UniProtKB=G3QMV6 G3QMV6 LOC101132319 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E10-RELATED GORGO|Ensembl=ENSGGOG00000040308.1|UniProtKB=A0A2I2ZLH7 A0A2I2ZLH7 PTHR12801:SF22 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED EXONUCLEASE GOR-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 exoribonuclease#PC00099;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005434.3|UniProtKB=G3QRQ9 G3QRQ9 EIF3G PTHR10352:SF88 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000038007.1|UniProtKB=A0A2I2Y2M4 A0A2I2Y2M4 PTHR10031:SF53 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE LIPID-BINDING PROTEIN ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004764.3|UniProtKB=G3QQ15 G3QQ15 MTMR11 PTHR10807:SF51 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 11 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000016029.3|UniProtKB=G3RIX0 G3RIX0 PLCL2 PTHR10336:SF84 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN INACTIVE PHOSPHOLIPASE C-LIKE PROTEIN 2 phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;lipase activity#GO:0016298 regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177 metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412 GORGO|Ensembl=ENSGGOG00000007796.3|UniProtKB=A0A2I2ZHQ2 A0A2I2ZHQ2 CASK PTHR23122:SF40 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PERIPHERAL PLASMA MEMBRANE PROTEIN CASK signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of secretion by cell#GO:1903530;regulation of biological process#GO:0050789;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;intracellular protein localization#GO:0008104;regulation of transport#GO:0051049;regulation of localization#GO:0032879;macromolecule localization#GO:0033036;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cell-cell junction#GO:0005911;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178 scaffold/adaptor protein#PC00226 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Parkinson disease#P00049>CASK#P01232 GORGO|Ensembl=ENSGGOG00000016869.3|UniProtKB=G3RL27 G3RL27 ASIC3 PTHR11690:SF228 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 3 metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003593.3|UniProtKB=G3QM11 G3QM11 OBSL1 PTHR35971:SF6 SI:DKEY-31G6.6 OBSCURIN-LIKE PROTEIN 1 regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;positive regulation of cell differentiation#GO:0045597;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;cellular component organization#GO:0016043;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of nervous system development#GO:0051960;microtubule cytoskeleton organization#GO:0000226;positive regulation of cell projection organization#GO:0031346;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of dendrite morphogenesis#GO:0048814 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000042026.1|UniProtKB=A0A2I2ZPA7 A0A2I2ZPA7 PTHR45883:SF6 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN-RELATED protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;heat shock protein binding#GO:0031072 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 GORGO|Ensembl=ENSGGOG00000024836.3|UniProtKB=A0A2I2YZY4 A0A2I2YZY4 DAB1 PTHR47695:SF4 PID DOMAIN-CONTAINING PROTEIN DISABLED HOMOLOG 1 cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell migration#GO:0016477;cell motility#GO:0048870;cell differentiation#GO:0030154;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neuron migration#GO:0001764;neurogenesis#GO:0022008;system development#GO:0048731 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008149.3|UniProtKB=G3QYM7 G3QYM7 OAS2 PTHR11258:SF3 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE 2 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;cellular response to stimulus#GO:0051716;antiviral innate immune response#GO:0140374;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;response to virus#GO:0009615;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;defense response to other organism#GO:0098542;cell surface receptor signaling pathway#GO:0007166;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;response to peptide#GO:1901652 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829 nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003371.4|UniProtKB=A0A2I2Y2K4 A0A2I2Y2K4 CFI PTHR24253:SF91 TRANSMEMBRANE PROTEASE SERINE COMPLEMENT FACTOR I catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016173.3|UniProtKB=G3RJ95 G3RJ95 STING1 PTHR34339:SF1 STIMULATOR OF INTERFERON GENES PROTEIN STIMULATOR OF INTERFERON GENES PROTEIN guanyl nucleotide binding#GO:0019001;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome organization#GO:1905037;cellular process#GO:0009987;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;response to stimulus#GO:0050896;regulation of autophagy#GO:0010506;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;process utilizing autophagic mechanism#GO:0061919;immune system process#GO:0002376;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of innate immune response#GO:0045088;defense response#GO:0006952;regulation of catabolic process#GO:0009894;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of type I interferon production#GO:0032481;response to virus#GO:0009615;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;positive regulation of response to external stimulus#GO:0032103;regulation of macroautophagy#GO:0016241;metabolic process#GO:0008152;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of macroautophagy#GO:0016239;cellular component organization#GO:0016043;defense response to virus#GO:0051607;positive regulation of metabolic process#GO:0009893;response to other organism#GO:0051707;macroautophagy#GO:0016236;regulation of macromolecule biosynthetic process#GO:0010556;reticulophagy#GO:0061709;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;positive regulation of gene expression#GO:0010628;regulation of response to stress#GO:0080134;positive regulation of cytokine production#GO:0001819;catabolic process#GO:0009056;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;positive regulation of biosynthetic process#GO:0009891;vacuole organization#GO:0007033;organelle assembly#GO:0070925 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;autophagosome#GO:0005776;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000022099.2|UniProtKB=G3RP85 G3RP85 TRAF7 PTHR22847:SF731 WD40 REPEAT PROTEIN TNF RECEPTOR-ASSOCIATED FACTOR 7 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000003234.3|UniProtKB=A0A2I2YD61 A0A2I2YD61 STK4 PTHR48015:SF32 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE 4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;negative regulation of signal transduction#GO:0009968;hippo signaling#GO:0035329;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023665.2|UniProtKB=G3RTV9 G3RTV9 ZFAND1 PTHR14677:SF37 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 1 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;organelle disassembly#GO:1903008;protein-RNA complex organization#GO:0071826;cellular component disassembly#GO:0022411 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000025271.2|UniProtKB=A0A2I2ZQ21 A0A2I2ZQ21 LOC101150221 PTHR11761:SF24 50S/60S RIBOSOMAL PROTEIN L14/L23 LARGE RIBOSOMAL SUBUNIT PROTEIN UL14 rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025825.2|UniProtKB=A0A2I2ZBN2 A0A2I2ZBN2 LOC109024736 PTHR23503:SF104 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000011806.3|UniProtKB=G3R820 G3R820 METTL27 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 transferase#PC00220;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000007108.3|UniProtKB=G3QW14 G3QW14 ALDH2 PTHR11699:SF233 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 metabolic process#GO:0008152;response to chemical#GO:0042221;detoxification#GO:0098754;aldehyde catabolic process#GO:0046185;cellular response to toxic substance#GO:0097237;cellular response to oxygen-containing compound#GO:1901701;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;cellular detoxification of aldehyde#GO:0110095;cellular response to stimulus#GO:0051716 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000024028.2|UniProtKB=A0A2I2ZJI2 A0A2I2ZJI2 LOC101127388 PTHR24062:SF181 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 4 binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011440.3|UniProtKB=G3R726 G3R726 PIM2 PTHR22984:SF10 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE PIM-2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;regulation of mitotic cell cycle#GO:0007346;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007289.3|UniProtKB=G3SF05 G3SF05 SECISBP2L PTHR13284:SF10 GH01354P SELENOCYSTEINE INSERTION SEQUENCE-BINDING PROTEIN 2-LIKE mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;mRNA 3'-UTR binding#GO:0003730;protein-containing complex binding#GO:0044877 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000022388.2|UniProtKB=G3SJX3 G3SJX3 NACC1 PTHR46105:SF3 AGAP004733-PA NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007002.3|UniProtKB=G3QVR9 G3QVR9 EEF1B2 PTHR11595:SF60 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-BETA guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000001343.3|UniProtKB=G3QG74 G3QG74 HOXD9 PTHR45970:SF4 AGAP004664-PA HOMEOBOX PROTEIN HOX-D9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;skeletal system development#GO:0001501;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development#GO:0009790;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;skeletal system morphogenesis#GO:0048705;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000014507.3|UniProtKB=G3REZ7 G3REZ7 NEU3 PTHR10628:SF23 SIALIDASE SIALIDASE-3 catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate catabolic process#GO:0016052;ceramide metabolic process#GO:0006672;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;liposaccharide metabolic process#GO:1903509;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;cellular process#GO:0009987 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000012095.3|UniProtKB=G3SK78 G3SK78 MOB3C PTHR22599:SF12 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3C kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000003477.3|UniProtKB=G3QLQ7 G3QLQ7 B4GALT6 PTHR19300:SF47 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 6 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000001149.3|UniProtKB=G3QFQ4 G3QFQ4 PTHR16243:SF2 BTG3-ASSOCIATED NUCLEAR PROTEIN BANP PROTEIN BANP GORGO|Ensembl=ENSGGOG00000007760.3|UniProtKB=A0A2I2ZCB7 A0A2I2ZCB7 MAP7D2 PTHR15073:SF3 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 2 cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000007886.3|UniProtKB=G3QXZ4 G3QXZ4 LOC101154167 PTHR11461:SF289 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-1-ANTITRYPSIN-RELATED PROTEIN enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000001699.3|UniProtKB=G3SBM5 G3SBM5 GUF1 PTHR43512:SF7 TRANSLATION FACTOR GUF1-RELATED TRANSLATION FACTOR GUF1, MITOCHONDRIAL ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of translation#GO:0045727;positive regulation of protein metabolic process#GO:0051247 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000007308.3|UniProtKB=A0A2I2YRI4 A0A2I2YRI4 MATR3 PTHR15592:SF2 MATRIN 3/NUCLEAR PROTEIN 220-RELATED MATRIN-3 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000007945.3|UniProtKB=G3QY47 G3QY47 DNASE1 PTHR11371:SF27 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1 DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 endodeoxyribonuclease#PC00093 GORGO|Ensembl=ENSGGOG00000027831.2|UniProtKB=G3SAB7 G3SAB7 ZNF444 PTHR23226:SF150 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 444 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013882.3|UniProtKB=G3RDD7 G3RDD7 GRXCR2 PTHR46926:SF1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 2 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 2 multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;system process#GO:0003008;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stereocilium#GO:0032420;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membraneless organelle#GO:0043228;actin-based cell projection#GO:0098858;microvillus#GO:0005902;neuron projection#GO:0043005;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000043357.1|UniProtKB=A0A2I2Z923 A0A2I2Z923 PTHR45883:SF3 HSC70-INTERACTING PROTEIN PROTEIN FAM10A4-RELATED Hsp70 protein binding#GO:0030544;protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 GORGO|Ensembl=ENSGGOG00000008846.3|UniProtKB=A0A2I2YML3 A0A2I2YML3 SPO11 PTHR10848:SF0 MEIOTIC RECOMBINATION PROTEIN SPO11 MEIOTIC RECOMBINATION PROTEIN SPO11 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stress#GO:0006950;meiotic DNA double-strand break formation#GO:0042138;organelle organization#GO:0006996;cellular process#GO:0009987;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 endodeoxyribonuclease#PC00093 GORGO|Ensembl=ENSGGOG00000006693.3|UniProtKB=G3QUZ4 G3QUZ4 NET1 PTHR46006:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000015617.3|UniProtKB=G3RHV7 G3RHV7 MMP28 PTHR10201:SF298 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-28 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000026051.2|UniProtKB=G3RTP4 G3RTP4 PTHR15438:SF4 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B15-RELATED GORGO|Ensembl=ENSGGOG00000006313.3|UniProtKB=G3QTY9 G3QTY9 HK2 PTHR19443:SF4 HEXOKINASE HEXOKINASE-2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;hexokinase activity#GO:0004396;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;pyruvate metabolic process#GO:0006090;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;glucose homeostasis#GO:0042593;ADP catabolic process#GO:0046032;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;ADP metabolic process#GO:0046031;cellular homeostasis#GO:0019725;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;intracellular glucose homeostasis#GO:0001678;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;carbohydrate homeostasis#GO:0033500;ribonucleoside diphosphate metabolic process#GO:0009185;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleotide catabolic process#GO:0006195;glucose 6-phosphate metabolic process#GO:0051156;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;energy derivation by oxidation of organic compounds#GO:0015980;intracellular chemical homeostasis#GO:0055082;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261 organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966;Glycolysis#P00024>Hexokinase#P00677 GORGO|Ensembl=ENSGGOG00000011819.3|UniProtKB=A0A2I2YXU3 A0A2I2YXU3 GLCCI1 PTHR14972:SF3 AGAP011572-PA GLUCOCORTICOID-INDUCED TRANSCRIPT 1 PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000012330.3|UniProtKB=G3R9F2 G3R9F2 CDH13 PTHR24027:SF80 CADHERIN-23 CADHERIN-13 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell migration#GO:0016477;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Gene=MYD88|UniProtKB=B3Y680 B3Y680 MYD88 PTHR15079:SF11 MYD88 MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;response to other organism#GO:0051707;toll-like receptor 4 signaling pathway#GO:0034142;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;activation of innate immune response#GO:0002218;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;defense response to Gram-positive bacterium#GO:0050830;defense response to bacterium#GO:0042742;immune system process#GO:0002376;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;activation of immune response#GO:0002253;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>MyD88#P01377 GORGO|Ensembl=ENSGGOG00000009124.3|UniProtKB=A0A2I2ZIZ1 A0A2I2ZIZ1 EEIG2 PTHR21456:SF3 FAMILY WITH SEQUENCE SIMILARITY 102 EEIG FAMILY MEMBER 2 GORGO|Ensembl=ENSGGOG00000028096.2|UniProtKB=G3S7V4 G3S7V4 TMEM51 PTHR16015:SF0 TRANSMEMBRANE PROTEIN 51 TRANSMEMBRANE PROTEIN 51 GORGO|Ensembl=ENSGGOG00000008889.3|UniProtKB=G3SG66 G3SG66 HSP90AB1 PTHR11528:SF79 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-BETA-RELATED ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;ATP binding#GO:0005524;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of protein stability#GO:0031647;response to stress#GO:0006950;cellular response to heat#GO:0034605;response to heat#GO:0009408;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein stabilization#GO:0050821;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein folding#GO:0006457;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538 perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 chaperone#PC00072;Hsp90 family chaperone#PC00028 GORGO|Ensembl=ENSGGOG00000009310.3|UniProtKB=G3SGK4 G3SGK4 TTC7A PTHR23083:SF475 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT PROTEIN 7A primary metabolic process#GO:0044238;protein localization to plasma membrane#GO:0072659;phosphorus metabolic process#GO:0006793;protein localization to membrane#GO:0072657;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;localization within membrane#GO:0051668;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000025824.2|UniProtKB=G3S0M4 G3S0M4 PTHR10031:SF32 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE LIPID-BINDING PROTEIN ATP synthase#PC00002;transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000002094.3|UniProtKB=G3QI60 G3QI60 CA12 PTHR18952:SF19 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 12 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878 apical part of cell#GO:0045177;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000022633.2|UniProtKB=G3SHW5 G3SHW5 PTHR45710:SF40 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER A molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell communication#GO:0007154;immune system process#GO:0002376;cell activation#GO:0001775;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;T cell activation#GO:0042110;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune response-activating signaling pathway#GO:0002757;T cell receptor signaling pathway#GO:0050852;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000043990.1|UniProtKB=A0A2I2YUK5 A0A2I2YUK5 PTHR12138:SF159 PRIMATE-EXPANDED PROTEIN FAMILY SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000037303.1|UniProtKB=A0A2I2ZLC8 A0A2I2ZLC8 PTHR11353:SF188 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000036511.1|UniProtKB=A0A2I2ZT55 A0A2I2ZT55 CCR1 PTHR10489:SF711 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 1 cytokine receptor activity#GO:0004896;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;defense response#GO:0006952;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000015888.3|UniProtKB=G3RS19 G3RS19 TINAGL1 PTHR12411:SF270 CYSTEINE PROTEASE FAMILY C1-RELATED TUBULOINTERSTITIAL NEPHRITIS ANTIGEN-LIKE catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000001785.3|UniProtKB=G3QHD3 G3QHD3 PGAP1 PTHR15495:SF7 NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED GPI INOSITOL-DEACYLASE catalytic activity#GO:0003824;deacylase activity#GO:0160215 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001329.3|UniProtKB=G3RRZ9 G3RRZ9 KCNK4 PTHR11003:SF30 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 4 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000006468.3|UniProtKB=G3QUC5 G3QUC5 MRPS31 PTHR13231:SF3 MITOCHONDRIAL RIBOSOMAL PROTEIN S31 SMALL RIBOSOMAL SUBUNIT PROTEIN MS31 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016609.4|UniProtKB=A0A2I2YA70 A0A2I2YA70 CNTN1 PTHR13817:SF77 TITIN CONTACTIN 1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000022480.2|UniProtKB=G3S4A0 G3S4A0 PTHR14614:SF117 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT-RELATED transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;lysine N-methyltransferase activity#GO:0016278 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003302.3|UniProtKB=G3QLA3 G3QLA3 KDM1B PTHR10742:SF410 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000003737.3|UniProtKB=G3QMD4 G3QMD4 TRAPPC2 PTHR12403:SF1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-RELATED intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006268.3|UniProtKB=G3QTU1 G3QTU1 IGFALS PTHR45617:SF2 LEUCINE RICH REPEAT FAMILY PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040669.1|UniProtKB=G3R6N1 G3R6N1 PTHR31324:SF1 MORF4 FAMILY-ASSOCIATED PROTEIN 1-RELATED MORF4 FAMILY-ASSOCIATED PROTEIN 1 GORGO|Ensembl=ENSGGOG00000005573.3|UniProtKB=G3QS35 G3QS35 MAP3K8 PTHR48016:SF31 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 8 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Toll receptor signaling pathway#P00054>TPL2#P01364 GORGO|Ensembl=ENSGGOG00000000321.3|UniProtKB=G3QDJ3 G3QDJ3 STAP1 PTHR16186:SF10 SIGNAL-TRANSDUCING ADAPTOR PROTEIN-RELATED SIGNAL-TRANSDUCING ADAPTOR PROTEIN 1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of B cell receptor signaling pathway#GO:0050855;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004492.3|UniProtKB=A0A2I2ZJP1 A0A2I2ZJP1 REEP4 PTHR12300:SF36 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 4 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015839.3|UniProtKB=G3S0T9 G3S0T9 KLHL35 PTHR24412:SF187 KELCH PROTEIN KELCH-LIKE PROTEIN 35 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008624.3|UniProtKB=G3QZW2 G3QZW2 TGS1 PTHR14741:SF32 S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED TRIMETHYLGUANOSINE SYNTHASE catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006113.3|UniProtKB=A0A2I2YCK1 A0A2I2YCK1 MTRES1 PTHR13633:SF3 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000012197.3|UniProtKB=G3R927 G3R927 RASL11B PTHR45704:SF6 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11B GORGO|Ensembl=ENSGGOG00000007512.3|UniProtKB=G3QX25 G3QX25 SLC10A6 PTHR10361:SF55 SODIUM-BILE ACID COTRANSPORTER SODIUM-DEPENDENT ORGANIC ANION TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;bile acid transmembrane transporter activity#GO:0015125;solute:sodium symporter activity#GO:0015370 establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869;macromolecule localization#GO:0033036 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000016998.3|UniProtKB=G3RLE6 G3RLE6 ST3GAL6 PTHR13713:SF8 SIALYLTRANSFERASE TYPE 2 LACTOSAMINE ALPHA-2,3-SIALYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;glycoprotein metabolic process#GO:0009100;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000043971.1|UniProtKB=A0A2I2Y343 A0A2I2Y343 MDFIC2 PTHR15304:SF2 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR DOMAIN-CONTAINING PROTEIN 2 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of JNK cascade#GO:0046328;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010333.3|UniProtKB=A0A2I2YTK5 A0A2I2YTK5 SLC26A1 PTHR11814:SF31 SULFATE TRANSPORTER SULFATE ANION TRANSPORTER 1 dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025086.2|UniProtKB=A0A2I2YY19 A0A2I2YY19 ABCC13 PTHR24223:SF166 ATP-BINDING CASSETTE SUB-FAMILY C ATP BINDING CASSETTE SUBFAMILY C MEMBER 13 (PSEUDO xenobiotic transmembrane transporter activity#GO:0042910;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000002024.3|UniProtKB=G3QI04 G3QI04 LOC101142243 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000027916.2|UniProtKB=G3RPV2 G3RPV2 PTGS2 PTHR11903:SF8 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G_H SYNTHASE 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;arachidonate metabolic process#GO:0019369;small molecule metabolic process#GO:0044281;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;prostaglandin metabolic process#GO:0006693;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;unsaturated fatty acid biosynthetic process#GO:0006636;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;monocarboxylic acid biosynthetic process#GO:0072330 neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 CCKR signaling map#P06959>COX2#G06998;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cyclooxygenase#P00845;Toll receptor signaling pathway#P00054>Gene trancription#G01550;CCKR signaling map#P06959>COX2#G07292;Endothelin signaling pathway#P00019>COX-2#P00582;CCKR signaling map#P06959>COX2#P07080 GORGO|Ensembl=ENSGGOG00000006048.3|UniProtKB=G3S0Z0 G3S0Z0 LARP1 PTHR22792:SF51 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014368.3|UniProtKB=G3REN1 G3REN1 ENTPD5 PTHR11782:SF35 ADENOSINE/GUANOSINE DIPHOSPHATASE NUCLEOSIDE DIPHOSPHATE PHOSPHATASE ENTPD5 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;metabolic process#GO:0008152;organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181;nucleotide phosphatase#PC00173;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000042155.1|UniProtKB=A0A2I2YRU3 A0A2I2YRU3 PTHR23115:SF222 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 1-RELATED translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000039816.1|UniProtKB=A0A2I2Z189 A0A2I2Z189 SLC35F6 PTHR13146:SF0 SOLUTE CARRIER FAMILY 35 MEMBER F6-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F6 intracellular organelle#GO:0043229;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000000234.3|UniProtKB=G3QDC0 G3QDC0 TRDN PTHR14106:SF0 TRIADIN TRIADIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;release of sequestered calcium ion into cytosol#GO:0051209;monoatomic cation transmembrane transport#GO:0098655;calcium ion transmembrane import into cytosol#GO:0097553;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of transport#GO:0051049;regulation of localization#GO:0032879;calcium ion transmembrane transport#GO:0070588;heart process#GO:0003015;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;multicellular organismal process#GO:0032501;regulation of monoatomic ion transport#GO:0043269;blood circulation#GO:0008015;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic ion transmembrane transport#GO:0034220;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of monoatomic cation transmembrane transport#GO:1904062;transport#GO:0006810;establishment of localization#GO:0051234;heart contraction#GO:0060047;system process#GO:0003008;regulation of transmembrane transport#GO:0034762;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;metal ion transport#GO:0030001;circulatory system process#GO:0003013;localization#GO:0051179;monoatomic cation transport#GO:0006812 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;sarcoplasmic reticulum#GO:0016529;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000009055.4|UniProtKB=A0A2I2YQJ8 A0A2I2YQJ8 GSE1 PTHR17608:SF4 GENETIC SUPPRESSOR ELEMENT 1 GENETIC SUPPRESSOR ELEMENT 1 GORGO|Ensembl=ENSGGOG00000005105.3|UniProtKB=G3QQX2 G3QQX2 CENPK PTHR14401:SF6 CENTROMERE PROTEIN K CENTROMERE PROTEIN K GORGO|Ensembl=ENSGGOG00000036425.1|UniProtKB=A0A2I2YSW2 A0A2I2YSW2 LOC101146227 PTHR19970:SF25 RIBOSOMAL PROTEIN L39E LARGE RIBOSOMAL SUBUNIT PROTEIN EL39 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005439.3|UniProtKB=G3QRR4 G3QRR4 NEK2 PTHR43671:SF115 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 mitotic cell cycle phase transition#GO:0044772;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule organizing center organization#GO:0031023;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;cytoskeleton organization#GO:0007010 microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006837.3|UniProtKB=G3QVC6 G3QVC6 GABRA2 PTHR18945:SF218 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-2 transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023 cellular process#GO:0009987;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;chloride transport#GO:0006821;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;signaling#GO:0023052;synapse assembly#GO:0007416;animal gross anatomical part developmental process#GO:0160108;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476 cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell projection membrane#GO:0031253;dendrite#GO:0030425;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000009900.3|UniProtKB=G3R350 G3R350 TAX1BP3 PTHR48620:SF1 TAX1-BINDING PROTEIN 3 TAX1-BINDING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000039109.1|UniProtKB=A0A2I2YES4 A0A2I2YES4 PTHR23266:SF236 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000016208.3|UniProtKB=A0A2I2YDN8 A0A2I2YDN8 CSNK1E PTHR11909:SF523 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM EPSILON phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>CK1delta/epsilon#P07089;Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Circadian clock system#P00015>Casein kinase I#P00502;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 GORGO|Ensembl=ENSGGOG00000014653.3|UniProtKB=A0A2I2ZFQ3 A0A2I2ZFQ3 ZNF548 PTHR23226:SF394 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 749 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024158.2|UniProtKB=A0A2I2Z249 A0A2I2Z249 PTHR46734:SF5 TELOMERIC REPEAT-BINDING FACTOR 1 TERF1 TELOMERIC REPEAT-BINDING FACTOR DNA polymerase activity#GO:0034061;telomerase activity#GO:0003720;catalytic activity, acting on DNA#GO:0140097;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA binding#GO:0003677;RNA-directed DNA polymerase activity#GO:0003964;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of chromosome organization#GO:2001251;telomere organization#GO:0032200;negative regulation of cellular component organization#GO:0051129;nucleic acid metabolic process#GO:0090304;negative regulation of organelle organization#GO:0010639;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;RNA-templated DNA biosynthetic process#GO:0006278;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;regulation of telomere maintenance#GO:0032204;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleic acid biosynthetic process#GO:0141187;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;nuclear telomere cap complex#GO:0000783;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000008357.3|UniProtKB=G3QZ70 G3QZ70 PRKCH PTHR24351:SF198 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000014843.4|UniProtKB=A0A2I2Z6G0 A0A2I2Z6G0 CTNND2 PTHR10372:SF9 PLAKOPHILLIN-RELATED CATENIN DELTA-2 protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 neurogenesis#GO:0022008;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;system development#GO:0048731;anatomical structure development#GO:0048856;synapse organization#GO:0050808;postsynapse organization#GO:0099173;dendritic spine morphogenesis#GO:0060997;cell junction organization#GO:0034330;dendritic spine development#GO:0060996;dendrite morphogenesis#GO:0048813;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;dendritic spine organization#GO:0097061;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;neuron development#GO:0048666;dendrite development#GO:0016358;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;neuron projection organization#GO:0106027;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 adherens junction#GO:0005912;cell junction#GO:0030054;cell periphery#GO:0071944;nucleus#GO:0005634;cell-cell junction#GO:0005911;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279 cytoskeletal protein#PC00085;intermediate filament#PC00129;intermediate filament binding protein#PC00130 Cadherin signaling pathway#P00012>P120#P00473 GORGO|Ensembl=ENSGGOG00000022806.2|UniProtKB=G3RV46 G3RV46 PTHR32414:SF2 NEUROMEDIN-S NEUROMEDIN-S GORGO|Ensembl=ENSGGOG00000039842.1|UniProtKB=A0A2I2Y406 A0A2I2Y406 PTHR11730:SF100 AMMONIUM TRANSPORTER BLOOD GROUP RH(CE) POLYPEPTIDE channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040183.1|UniProtKB=G3RNZ8 G3RNZ8 AMT PTHR43757:SF2 AMINOMETHYLTRANSFERASE AMINOMETHYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transferase#PC00220;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000001316.3|UniProtKB=G3RT56 G3RT56 PTHR43294:SF1 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;primary active transmembrane transporter activity#GO:0015399;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 transmembrane transport#GO:0055085;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;export from cell#GO:0140352;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001243.3|UniProtKB=Q0MQH0 Q0MQH0 NDUFS4 PTHR12219:SF28 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular respiration#GO:0045333;electron transport chain#GO:0022900;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007560.3|UniProtKB=G3QX65 G3QX65 LOC101127012 PTHR10044:SF167 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 8 enzyme regulator activity#GO:0030234;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of signal transduction#GO:0009967;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of protein ubiquitination#GO:0031396;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of protein modification process#GO:0031399;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;regulation of cell cycle#GO:0051726;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;positive regulation of signaling#GO:0023056;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of Wnt signaling pathway#GO:0030177;regulation of apoptotic process#GO:0042981 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000038422.1|UniProtKB=A0A2I2Z774 A0A2I2Z774 PTHR10517:SF23 FOLATE RECEPTOR FOLATE RECEPTOR-LIKE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;cargo receptor activity#GO:0038024;signaling receptor activity#GO:0038023 carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;localization#GO:0051179;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;dicarboxylic acid transport#GO:0006835;vitamin transport#GO:0051180 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000040208.1|UniProtKB=A0A2I2YEY8 A0A2I2YEY8 PTHR15532:SF2 FAMILY NOT NAMED DERMATAN-SULFATE EPIMERASE-LIKE PROTEIN racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;isomerase activity#GO:0016853 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 GORGO|Ensembl=ENSGGOG00000001119.3|UniProtKB=G3SAB8 G3SAB8 PGAP3 PTHR13148:SF0 PER1-RELATED GPI-SPECIFIC PHOSPHOLIPASE A2-LIKE PGAP3 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000017158.3|UniProtKB=G3RLT5 G3RLT5 FBXO7 PTHR15537:SF2 F-BOX ONLY PROTEIN 7 F-BOX ONLY PROTEIN 7 GORGO|Ensembl=ENSGGOG00000009243.3|UniProtKB=A0A2I2YUN5 A0A2I2YUN5 UBXN6 PTHR23153:SF38 UBX-RELATED UBX DOMAIN-CONTAINING PROTEIN 6 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000011702.3|UniProtKB=G3SER3 G3SER3 EIF3F PTHR10540:SF16 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F peptidase activity#GO:0008233;translation initiation factor activity#GO:0003743;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;translation initiation factor binding#GO:0031369;translation factor activity#GO:0180051;catalytic activity#GO:0003824;protein binding#GO:0005515;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;binding#GO:0005488 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000006212.3|UniProtKB=G3QTP5 G3QTP5 MRAP2 PTHR28675:SF1 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;protein binding#GO:0005515 localization within membrane#GO:0051668;regulation of signaling#GO:0023051;localization#GO:0051179;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;protein localization to cell periphery#GO:1990778;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000007455.3|UniProtKB=G3QWX2 G3QWX2 SAMD7 PTHR12247:SF89 POLYCOMB GROUP PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 7 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000038865.1|UniProtKB=A0A2I2ZXR1 A0A2I2ZXR1 PTHR46232:SF4 SMARCE1 REGULATOR OF CHROMATIN HMG BOX DOMAIN-CONTAINING PROTEIN transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000026626.2|UniProtKB=A0A2I2ZTE3 A0A2I2ZTE3 PTHR11158:SF32 MSF1/PX19 RELATED PRELI_MSF1 DOMAIN-CONTAINING PROTEIN molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036;localization#GO:0051179;establishment of localization#GO:0051234;lipid localization#GO:0010876;transport#GO:0006810 intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000001889.3|UniProtKB=G3QQK7 G3QQK7 TUBB4B PTHR11588:SF247 TUBULIN TUBULIN BETA-4B CHAIN nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>beta-Tubulin#P00790 GORGO|Ensembl=ENSGGOG00000003625.3|UniProtKB=A0A2I2YZZ2 A0A2I2YZZ2 FBXL19 PTHR23123:SF35 PHD/F-BOX CONTAINING PROTEIN F-BOX_LRR-REPEAT PROTEIN 19 histone demethylase activity#GO:0032452;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;protein-macromolecule adaptor activity#GO:0030674;histone modifying activity#GO:0140993;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;chromatin remodeling#GO:0006338;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;modification-dependent protein catabolic process#GO:0019941;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;chromatin organization#GO:0006325;cellular process#GO:0009987 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000011034.3|UniProtKB=G3R619 G3R619 SERTAD1 PTHR16277:SF12 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 SERTA DOMAIN-CONTAINING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000013631.3|UniProtKB=G3SB18 G3SB18 ECM2 PTHR46544:SF1 EXTRACELLULAR MATRIX PROTEIN 2-RELATED EXTRACELLULAR MATRIX PROTEIN 2 protein-containing complex binding#GO:0044877;heparin binding#GO:0008201;collagen binding#GO:0005518;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;cellular process#GO:0009987;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 GORGO|Ensembl=ENSGGOG00000044072.1|UniProtKB=A0A2I2ZVF5 A0A2I2ZVF5 BCL10 PTHR34920:SF1 B-CELL LYMPHOMA/LEUKEMIA 10 B-CELL LYMPHOMA_LEUKEMIA 10 enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;transcription coactivator activity#GO:0003713;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;kinase binding#GO:0019900;binding#GO:0005488;molecular function activator activity#GO:0140677;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;immune system process#GO:0002376;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of signaling#GO:0023056 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000022385.2|UniProtKB=G3RZI2 G3RZI2 PTHR19818:SF69 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002407.3|UniProtKB=G3QIZ5 G3QIZ5 DYNLT5 PTHR21255:SF64 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 5 binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000036124.1|UniProtKB=A0A2I2YI91 A0A2I2YI91 PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000025554.2|UniProtKB=A0A2I2YAH6 A0A2I2YAH6 MSR1 PTHR19331:SF440 SCAVENGER RECEPTOR DOMAIN-CONTAINING MACROPHAGE SCAVENGER RECEPTOR TYPES I AND II protein-containing complex binding#GO:0044877;cargo receptor activity#GO:0038024;protein-lipid complex binding#GO:0071814;low-density lipoprotein particle binding#GO:0030169;peptide binding#GO:0042277;binding#GO:0005488;lipoprotein particle binding#GO:0071813 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;plasma lipoprotein particle clearance#GO:0034381;regulation of localization#GO:0032879 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000006410.3|UniProtKB=G3QU73 G3QU73 SMTNL2 PTHR23167:SF37 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SMOOTHELIN-LIKE PROTEIN 2 cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based process#GO:0030029 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006337.3|UniProtKB=A0A2I2ZD20 A0A2I2ZD20 MIB2 PTHR24202:SF4 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB2-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000014405.3|UniProtKB=G3RER4 G3RER4 TUSC3 PTHR12692:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT TUSC3 transmembrane transport#GO:0055085;protein metabolic process#GO:0019538;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;magnesium ion transport#GO:0015693;transport#GO:0006810;glycoprotein metabolic process#GO:0009100;monoatomic ion transmembrane transport#GO:0034220;biosynthetic process#GO:0009058;monoatomic cation transmembrane transport#GO:0098655;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004922.3|UniProtKB=G3QQF9 G3QQF9 SESN3 PTHR12474:SF4 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-3 cation binding#GO:0043169;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;ion binding#GO:0043167;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;small molecule binding#GO:0036094;oxidoreductase activity#GO:0016491;amino acid binding#GO:0016597;catalytic activity#GO:0003824 regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;negative regulation of TORC1 signaling#GO:1904262;regulation of macroautophagy#GO:0016241;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;response to acid chemical#GO:0001101;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;response to chemical#GO:0042221;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;positive regulation of macroautophagy#GO:0016239;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010647.3|UniProtKB=G3R513 G3R513 ANGPTL7 PTHR19143:SF40 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 7 anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;visual system development#GO:0150063;regulation of developmental process#GO:0050793;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;multicellular organism development#GO:0007275;animal organ development#GO:0048513;sensory organ development#GO:0007423;regulation of vasculature development#GO:1901342;developmental process#GO:0032502;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;sensory system development#GO:0048880 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000005901.3|UniProtKB=A0A2I2YK38 A0A2I2YK38 LPIN1 PTHR12181:SF10 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN1 transcription regulator activity#GO:0140110;hydrolase activity#GO:0016787;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transcription coactivator activity#GO:0003713;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;carboxylic acid metabolic process#GO:0019752;response to endogenous stimulus#GO:0009719;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;glycerolipid metabolic process#GO:0046486;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;lipid catabolic process#GO:0016042;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;glycerolipid biosynthetic process#GO:0045017;carboxylic acid catabolic process#GO:0046395;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to peptide hormone#GO:0043434;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;lipid biosynthetic process#GO:0008610;cellular response to nitrogen compound#GO:1901699;positive regulation of DNA-templated transcription#GO:0045893;monocarboxylic acid catabolic process#GO:0072329;triglyceride biosynthetic process#GO:0019432;regulation of nucleobase-containing compound metabolic process#GO:0019219;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;cellular response to insulin stimulus#GO:0032869;acylglycerol metabolic process#GO:0006639;fatty acid metabolic process#GO:0006631;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;neutral lipid metabolic process#GO:0006638 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;mitochondrial membrane#GO:0031966;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000011875.3|UniProtKB=A0A2I2YIJ1 A0A2I2YIJ1 TNRC18 PTHR12505:SF21 PHD FINGER TRANSCRIPTION FACTOR TRINUCLEOTIDE REPEAT-CONTAINING GENE 18 PROTEIN gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007793.4|UniProtKB=G3QXR6 G3QXR6 PTHR24064:SF217 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 25 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000003862.3|UniProtKB=G3QMP6 G3QMP6 TCEA2 PTHR11477:SF3 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 2 transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000042659.1|UniProtKB=A0A2I2YXQ9 A0A2I2YXQ9 PTHR12621:SF9 CYSTEINE AND HISTIDINE-RICH DOMAIN CHORD -CONTAINING PROTEIN CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;ion binding#GO:0043167;transition metal ion binding#GO:0046914 cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040405.1|UniProtKB=A0A2I2YA28 A0A2I2YA28 BLOC1S5 PTHR31784:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 microtubule-based process#GO:0007017;synaptic vesicle transport#GO:0048489;cellular process#GO:0009987;developmental pigmentation#GO:0048066;establishment of localization in cell#GO:0051649;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;organelle transport along microtubule#GO:0072384;cellular pigmentation#GO:0033059;establishment of vesicle localization#GO:0051650;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;establishment of organelle localization#GO:0051656;response to stimulus#GO:0050896;cell differentiation#GO:0030154;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;developmental process#GO:0032502;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;response to external stimulus#GO:0009605;anterograde synaptic vesicle transport#GO:0048490;vesicle cytoskeletal trafficking#GO:0099518;axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;developmental maturation#GO:0021700;organelle localization#GO:0051640;axonal transport#GO:0098930;pigmentation#GO:0043473;localization#GO:0051179;anterograde axonal transport#GO:0008089;cellular response to stimulus#GO:0051716;microtubule-based movement#GO:0007018 protein-containing complex#GO:0032991;BLOC-1 complex#GO:0031083;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000001701.3|UniProtKB=G3QH55 G3QH55 LOC101142081 PTHR26453:SF6 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G4-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014068.3|UniProtKB=G3RDV4 G3RDV4 ZNF550 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024616.2|UniProtKB=G3RYV0 G3RYV0 PTHR46803:SF5 E3 UBIQUITIN-PROTEIN LIGASE CHIP E3 UBIQUITIN-PROTEIN LIGASE CHIP protein-folding chaperone binding#GO:0051087;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of proteolysis#GO:0030162;positive regulation of macromolecule metabolic process#GO:0010604;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;response to misfolded protein#GO:0051788;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular response to misfolded protein#GO:0071218;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to topologically incorrect protein#GO:0035967;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;I band#GO:0031674 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>CHIP#P01214 GORGO|Ensembl=ENSGGOG00000022344.2|UniProtKB=G3RWP2 G3RWP2 LOC101143345 PTHR26453:SF589 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1A1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000041997.1|UniProtKB=A0A2I2Y7N4 A0A2I2Y7N4 PTHR28441:SF5 PROTEIN FAM91A1 FAM91A1 protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;Golgi apparatus subcompartment#GO:0098791 GORGO|Ensembl=ENSGGOG00000003335.3|UniProtKB=G3QLD4 G3QLD4 TTC14 PTHR23184:SF9 TETRATRICOPEPTIDE REPEAT PROTEIN 14 TETRATRICOPEPTIDE REPEAT PROTEIN 14 GORGO|Ensembl=ENSGGOG00000001820.3|UniProtKB=G3QHG5 G3QHG5 STK38L PTHR24356:SF160 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 38-LIKE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;establishment or maintenance of cell polarity#GO:0007163;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000014120.3|UniProtKB=G3RE10 G3RE10 CXCL13 PTHR12015:SF204 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 13 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000000003.3|UniProtKB=A0A2I2YRS6 A0A2I2YRS6 RUFY4 PTHR47732:SF1 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 4 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000015220.3|UniProtKB=G3RWK2 G3RWK2 PPP4R3A PTHR23318:SF3 ATP SYNTHASE GAMMA-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3A enzyme activator activity#GO:0008047;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;regulation of response to stress#GO:0080134;cellular response to stimulus#GO:0051716;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000001916.3|UniProtKB=G3S2X2 G3S2X2 LPXN PTHR24216:SF23 PAXILLIN-RELATED LEUPAXIN molecular sequestering activity#GO:0140313;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein sequestering activity#GO:0140311 regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of B cell receptor signaling pathway#GO:0050855;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585 actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell-cell junction#GO:0005911;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 VEGF signaling pathway#P00056>Paxillin#P01418;Angiogenesis#P00005>Paxillin#P00194 GORGO|Ensembl=ENSGGOG00000043146.1|UniProtKB=G3SG45 G3SG45 SLCO1B1 PTHR11388:SF89 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B1 active transmembrane transporter activity#GO:0022804;bile acid transmembrane transporter activity#GO:0015125;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;secondary active transmembrane transporter activity#GO:0015291 cellular process#GO:0009987;macromolecule localization#GO:0033036;lipid transport#GO:0006869;bile acid and bile salt transport#GO:0015721;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000043729.1|UniProtKB=A0A2I2ZEX5 A0A2I2ZEX5 RAB7B PTHR47981:SF22 RAB FAMILY RAS-RELATED PROTEIN RAB-7B GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;phagolysosome assembly#GO:0001845;intracellular transport#GO:0046907;phagocytosis#GO:0006909;vacuolar transport#GO:0007034;transport#GO:0006810;lytic vacuole organization#GO:0080171;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle organization#GO:0016050;cellular component organization#GO:0016043;endocytosis#GO:0006897;vesicle fusion#GO:0006906;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;organelle assembly#GO:0070925;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033 endomembrane system#GO:0012505;late endosome#GO:0005770;phagocytic vesicle#GO:0045335;cytoplasm#GO:0005737;vacuole#GO:0005773;lytic vacuole#GO:0000323;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000015346.3|UniProtKB=G3RH61 G3RH61 NFRKB PTHR13052:SF3 NFRKB-RELATED NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN protein binding#GO:0005515;binding#GO:0005488;protease binding#GO:0002020;enzyme binding#GO:0019899 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000012742.3|UniProtKB=G3RAF7 G3RAF7 KIF3B PTHR24115:SF744 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3B cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;microtubule-based movement#GO:0007018;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000012110.4|UniProtKB=G3R8V4 G3R8V4 SPON1 PTHR11311:SF16 SPONDIN SPONDIN-1 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000014448.3|UniProtKB=G3REU4 G3REU4 AMMECR1L PTHR13016:SF1 AMMECR1 HOMOLOG AMMECR1-LIKE PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000768.3|UniProtKB=G3QEQ8 G3QEQ8 HAMP PTHR16877:SF0 HEPCIDIN HEPCIDIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function inhibitor activity#GO:0140678;transporter regulator activity#GO:0141108 multicellular organismal process#GO:0032501;response to other organism#GO:0051707;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;response to biotic stimulus#GO:0009607;defense response#GO:0006952;cellular homeostasis#GO:0019725;multicellular organismal-level homeostasis#GO:0048871;response to external stimulus#GO:0009605;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular iron ion homeostasis#GO:0006879;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;defense response to Gram-positive bacterium#GO:0050830;response to bacterium#GO:0009617;inorganic ion homeostasis#GO:0098771;defense response to bacterium#GO:0042742 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000012840.3|UniProtKB=G3RAP6 G3RAP6 PMVK PTHR13101:SF1 PHOSPHOMEVALONATE KINASE PHOSPHOMEVALONATE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;cholesterol biosynthetic process#GO:0006695;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;isoprenoid biosynthetic process#GO:0008299;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;acyl-CoA metabolic process#GO:0006637;secondary alcohol biosynthetic process#GO:1902653;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610;organophosphate metabolic process#GO:0019637;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407;acetyl-CoA metabolic process#GO:0006084;phospholipid metabolic process#GO:0006644;nucleoside phosphate metabolic process#GO:0006753;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 Cholesterol biosynthesis#P00014>Phosphomevalonate kinase#P00500 GORGO|Ensembl=ENSGGOG00000024691.2|UniProtKB=G3RTN2 G3RTN2 RPL29 PTHR12884:SF43 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016823.3|UniProtKB=G3RKX7 G3RKX7 CHST11 PTHR12137:SF32 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 11 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000005002.3|UniProtKB=G3QQN3 G3QQN3 CRLF3 PTHR23389:SF12 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CYTOKINE RECEPTOR-LIKE FACTOR 3 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000000228.3|UniProtKB=G3QDB5 G3QDB5 DYNC1I1 PTHR12442:SF34 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;microtubule-based transport#GO:0099111;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;localization#GO:0051179;cellular localization#GO:0051641;transport along microtubule#GO:0010970;establishment of localization#GO:0051234 microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000005638.3|UniProtKB=G3QS93 G3QS93 SS18L1 PTHR23107:SF21 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN CALCIUM-RESPONSIVE TRANSACTIVATOR transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 positive regulation of cell differentiation#GO:0045597;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular component organization#GO:0051130;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cell projection organization#GO:0031344;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cell projection organization#GO:0031346;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;positive regulation of biosynthetic process#GO:0009891;regulation of neurogenesis#GO:0050767;regulation of dendrite morphogenesis#GO:0048814;positive regulation of RNA metabolic process#GO:0051254;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000014297.3|UniProtKB=G3REH7 G3REH7 PTHR28678:SF1 CODANIN-1 CODANIN-1 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015148.3|UniProtKB=G3RGM8 G3RGM8 MRPL46 PTHR13124:SF12 39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN ML46 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004236.3|UniProtKB=G3QNP0 G3QNP0 KNG1 PTHR13814:SF12 FETUIN KININOGEN-1 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 negative regulation of blood coagulation#GO:0030195;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;negative regulation of response to wounding#GO:1903035;regulation of response to wounding#GO:1903034;negative regulation of wound healing#GO:0061045;regulation of hemostasis#GO:1900046;negative regulation of cell adhesion#GO:0007162;regulation of coagulation#GO:0050818;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of cell adhesion#GO:0030155;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;negative regulation of hemostasis#GO:1900047;negative regulation of coagulation#GO:0050819;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of blood coagulation#GO:0030193;regulation of cellular process#GO:0050794;regulation of body fluid levels#GO:0050878;regulation of wound healing#GO:0061041 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>Bradykinin#P00438;Blood coagulation#P00011>HMWK#P00413;Blood coagulation#P00011>Kininogen#P00451 GORGO|Ensembl=ENSGGOG00000011772.3|UniProtKB=G3S538 G3S538 GOSR1 PTHR21094:SF2 GOS-28 SNARE- RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 1 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;localization#GO:0051179;intra-Golgi vesicle-mediated transport#GO:0006891;cellular component organization#GO:0016043;vesicle fusion#GO:0006906 membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;Golgi cisterna#GO:0031985;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi stack#GO:0005795;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 membrane traffic protein#PC00150;SNARE protein#PC00034 GORGO|Ensembl=ENSGGOG00000043967.1|UniProtKB=A0A2I2Z455 A0A2I2Z455 PTHR23267:SF402 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-39-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000044205.1|UniProtKB=A0A2I2YZD9 A0A2I2YZD9 PTHR10966:SF4 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA GAMMA CHAIN transcription factor binding#GO:0008134;binding#GO:0005488;protein binding#GO:0005515 DNA-templated transcription initiation#GO:0006352;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390;General transcription regulation#P00023>TFIIA complex#P00662 GORGO|Ensembl=ENSGGOG00000001724.3|UniProtKB=G3QH77 G3QH77 CES5A PTHR11559:SF43 CARBOXYLESTERASE CARBOXYLESTERASE 5A carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000016849.3|UniProtKB=G3RL10 G3RL10 ANGPT4 PTHR19143:SF31 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-4 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;receptor tyrosine kinase binding#GO:0030971 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000024826.2|UniProtKB=A0A2I2YR87 A0A2I2YR87 REL PTHR24169:SF4 NUCLEAR FACTOR NF-KAPPA-B PROTEIN PROTO-ONCOGENE C-REL nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;response to peptide#GO:1901652;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;intracellular signaling cassette#GO:0141124;defense response to other organism#GO:0098542;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;non-canonical NF-kappaB signal transduction#GO:0038061;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;response to other organism#GO:0051707;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;canonical NF-kappaB signal transduction#GO:0007249;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264 Toll receptor signaling pathway#P00054>NFkappaB#P01354;Apoptosis signaling pathway#P00006>NFkappaB#P00297;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859 GORGO|Ensembl=ENSGGOG00000008853.3|UniProtKB=G3R0H3 G3R0H3 UHRF2 PTHR14140:SF3 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED E3 UBIQUITIN-PROTEIN LIGASE UHRF2 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;metabolic process#GO:0008152;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;post-translational protein modification#GO:0043687;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000025421.2|UniProtKB=A0A2I2ZWR8 A0A2I2ZWR8 S100A10 PTHR11639:SF74 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A10 calcium ion binding#GO:0005509;transmembrane transporter binding#GO:0044325;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000000136.3|UniProtKB=G3QD30 G3QD30 CAV3 PTHR10844:SF16 CAVEOLIN CAVEOLIN-3 binding#GO:0005488;transmembrane transporter binding#GO:0044325;protein binding#GO:0005515 homeostatic process#GO:0042592;cell differentiation#GO:0030154;membrane assembly#GO:0071709;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;biological regulation#GO:0065007;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;monoatomic ion homeostasis#GO:0050801;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;cellular component organization or biogenesis#GO:0071840;regulation of membrane potential#GO:0042391;cellular developmental process#GO:0048869;developmental process#GO:0032502;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080 membrane microdomain#GO:0098857;anchoring junction#GO:0070161;cell junction#GO:0030054;sarcolemma#GO:0042383;plasma membrane raft#GO:0044853;cell periphery#GO:0071944;membrane#GO:0016020;caveola#GO:0005901;membrane raft#GO:0045121;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009098.3|UniProtKB=G3R146 G3R146 MRS2 PTHR13890:SF0 RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;magnesium ion transmembrane transporter activity#GO:0015095 magnesium ion transport#GO:0015693;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000009377.3|UniProtKB=G3R1T3 G3R1T3 PLEKHG3 PTHR45924:SF4 FI17866P1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 3 binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;regulation of establishment or maintenance of cell polarity#GO:0032878;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000040028.1|UniProtKB=A0A2I2Z9I6 A0A2I2Z9I6 CDK5R1 PTHR23401:SF2 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 1 kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase activator activity#GO:0030295;kinase activator activity#GO:0019209 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;central nervous system development#GO:0007417;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;head development#GO:0060322;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;anatomical structure development#GO:0048856;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;brain development#GO:0007420;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;axon#GO:0030424;growth cone#GO:0030426 kinase activator#PC00138;kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000012365.3|UniProtKB=G3R9I6 G3R9I6 PTHR24099:SF6 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 2 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000039081.1|UniProtKB=A0A2I2YQW9 A0A2I2YQW9 PRICKLE3 PTHR24211:SF19 LIM DOMAIN-CONTAINING PROTEIN PRICKLE PLANAR CELL POLARITY PROTEIN 3 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008984.3|UniProtKB=G3R0T9 G3R0T9 RBPMS2 PTHR10501:SF87 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B RNA-BINDING PROTEIN WITH MULTIPLE SPLICING 2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 negative regulation of biological process#GO:0048519;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;regulation of cell differentiation#GO:0045595;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000012314.3|UniProtKB=G3R9D3 G3R9D3 PTHR10772:SF67 10 KDA HEAT SHOCK PROTEIN 10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;protein-folding chaperone binding#GO:0051087 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000015026.3|UniProtKB=G3S0V0 G3S0V0 KIF26A PTHR21608:SF6 KINESIN-LIKE PROTEIN CG14535 KINESIN-LIKE PROTEIN KIF26A tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 regulation of cell migration#GO:0030334;regulation of neuron migration#GO:2001222;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell motility#GO:2000145;regulation of biological process#GO:0050789;regulation of neuron projection development#GO:0010975;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128 GORGO|Ensembl=ENSGGOG00000005356.3|UniProtKB=G3QRJ4 G3QRJ4 VPS33A PTHR11679:SF85 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;lytic vacuole#GO:0000323;vesicle tethering complex#GO:0099023;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000011384.3|UniProtKB=G3R6X5 G3R6X5 SELPLG PTHR17384:SF7 P-SELECTIN GLYCOPROTEIN LIGAND-1 P-SELECTIN GLYCOPROTEIN LIGAND 1 immune system process#GO:0002376;leukocyte migration#GO:0050900;cell adhesion#GO:0007155;cell migration#GO:0016477;cell motility#GO:0048870;cell-cell adhesion#GO:0098609;leukocyte cell-cell adhesion#GO:0007159;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000003747.3|UniProtKB=G3RYJ7 G3RYJ7 MDGA1 PTHR42757:SF30 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED OBSCURIN, CYTOSKELETAL CALMODULIN AND TITIN-INTERACTING RHOGEF cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000012735.3|UniProtKB=G3RAE5 G3RAE5 KCNMB4 PTHR10258:SF3 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-4 potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 biological regulation#GO:0065007;potassium ion transport#GO:0006813;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;cellular process#GO:0009987;detection of stimulus#GO:0051606;transmission of nerve impulse#GO:0019226;system process#GO:0003008;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;response to metal ion#GO:0010038;transport#GO:0006810;metal ion transport#GO:0030001;response to stimulus#GO:0050896;action potential#GO:0001508;detection of chemical stimulus#GO:0009593;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;response to calcium ion#GO:0051592;nervous system process#GO:0050877 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000027675.2|UniProtKB=A0A2I2ZNB4 A0A2I2ZNB4 PTHR23409:SF37 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE cellular process#GO:0009987;metabolic process#GO:0008152;biosynthetic process#GO:0009058 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 reductase#PC00198;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000014716.3|UniProtKB=G3RFI9 G3RFI9 LOC101138067 PTHR24300:SF364 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 binding#GO:0005488;steroid hydroxylase activity#GO:0008395;tetrapyrrole binding#GO:0046906;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 lipid metabolic process#GO:0006629;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;steroid metabolic process#GO:0008202;response to stimulus#GO:0050896;response to chemical#GO:0042221 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000005900.3|UniProtKB=G3QSY0 G3QSY0 OCA2 PTHR43568:SF2 P PROTEIN P PROTEIN biosynthetic process#GO:0009058;developmental pigmentation#GO:0048066;cellular process#GO:0009987;melanocyte differentiation#GO:0030318;pigment metabolic process#GO:0042440;phenol-containing compound biosynthetic process#GO:0046189;secondary metabolic process#GO:0019748;cellular developmental process#GO:0048869;pigment biosynthetic process#GO:0046148;developmental process#GO:0032502;secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;cell differentiation#GO:0030154;phenol-containing compound metabolic process#GO:0018958;melanin biosynthetic process#GO:0042438;pigmentation#GO:0043473 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;melanosome#GO:0042470;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000034815.2|UniProtKB=A0A2I2Y4R5 A0A2I2Y4R5 RO60 PTHR14202:SF0 60 KDA RIBONUCLEOPROTEIN SSA/RO RNA-BINDING PROTEIN RO60 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000022716.2|UniProtKB=G3S828 G3S828 LOC115931267 PTHR16471:SF3 CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN-LIKE PROTEIN CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN GORGO|Ensembl=ENSGGOG00000004937.3|UniProtKB=G3QQH0 G3QQH0 LOC101150995 PTHR35664:SF1 SPERMATID-SPECIFIC MANCHETTE-RELATED PROTEIN 1 SPERM MICROTUBULE INNER PROTEIN 6 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 GORGO|Gene=SCML1|UniProtKB=B0FZN8 B0FZN8 SCML1 PTHR12247:SF128 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 1 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000009704.3|UniProtKB=G3SBW8 G3SBW8 ECHDC3 PTHR43602:SF1 FAMILY NOT NAMED ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000015914.3|UniProtKB=G3RIL6 G3RIL6 PTHR38498:SF2 TRANSMEMBRANE PROTEIN 191B-RELATED TRANSMEMBRANE PROTEIN 191B GORGO|Ensembl=ENSGGOG00000039278.1|UniProtKB=A0A2I2ZT67 A0A2I2ZT67 PTHR11616:SF96 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;amino acid transport#GO:0006865;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 GORGO|Ensembl=ENSGGOG00000006584.3|UniProtKB=G3QUN6 G3QUN6 CATSPER4 PTHR47077:SF1 ION_TRANS DOMAIN-CONTAINING PROTEIN CATION CHANNEL SPERM-ASSOCIATED PROTEIN 4 transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267 sexual reproduction#GO:0019953;spermatid development#GO:0007286;multicellular organismal reproductive process#GO:0048609;localization#GO:0051179;monoatomic cation transport#GO:0006812;anatomical structure development#GO:0048856;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;metal ion transport#GO:0030001;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;spermatogenesis#GO:0007283;developmental process#GO:0032502;transport#GO:0006810;flagellated sperm motility#GO:0030317;cell maturation#GO:0048469;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;developmental maturation#GO:0021700;male gamete generation#GO:0048232;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;monoatomic ion transport#GO:0006811;cilium-dependent cell motility#GO:0060285;sperm motility#GO:0097722;sodium ion transport#GO:0006814;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cell differentiation#GO:0030154;gamete generation#GO:0007276;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;sperm capacitation#GO:0048240 plasma membrane#GO:0005886;endomembrane system#GO:0012505;monoatomic ion channel complex#GO:0034702;sperm flagellum#GO:0036126;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;transmembrane transporter complex#GO:1902495;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;secretory vesicle#GO:0099503;transporter complex#GO:1990351;cation channel complex#GO:0034703;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;calcium channel complex#GO:0034704;sperm principal piece#GO:0097228;intracellular vesicle#GO:0097708;voltage-gated calcium channel complex#GO:0005891;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669 GORGO|Ensembl=ENSGGOG00000009451.3|UniProtKB=A0A2I2ZTT2 A0A2I2ZTT2 HSPA2 PTHR19375:SF382 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK-RELATED 70 KDA PROTEIN 2 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 Hsp70 family chaperone#PC00027;chaperone#PC00072 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 GORGO|Ensembl=ENSGGOG00000005903.3|UniProtKB=G3QSX7 G3QSX7 TMEM204 PTHR14627:SF0 TRANSMEMBRANE PROTEIN 204 TRANSMEMBRANE PROTEIN 204 regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000026122.2|UniProtKB=G3SID0 G3SID0 PTHR12783:SF5 RALA BINDING PROTEIN 1 RALBP1 RALA-BINDING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;signal transduction#GO:0007165;vesicle-mediated transport#GO:0016192;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000013512.3|UniProtKB=G3RCF1 G3RCF1 PDE6D PTHR12976:SF0 RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE DELTA-SUBUNIT RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT DELTA cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000038672.1|UniProtKB=A0A2I2Z7M7 A0A2I2Z7M7 CACNB4 PTHR11824:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-4 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;signaling#GO:0023052;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 voltage-gated ion channel#PC00241 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 GORGO|Ensembl=ENSGGOG00000000920.3|UniProtKB=G3QF43 G3QF43 PSMC4 PTHR23073:SF155 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6B macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 protease#PC00190 Ubiquitin proteasome pathway#P00060>19S proteasome#P01494;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000009653.3|UniProtKB=G3R2H9 G3R2H9 GLI2 PTHR45718:SF6 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTION ACTIVATOR GLI2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 smoothened signaling pathway#GO:0007224;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 GORGO|Ensembl=ENSGGOG00000027276.2|UniProtKB=G3S5D8 G3S5D8 LOC101128557 PTHR26452:SF247 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5K3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001802.3|UniProtKB=G3QHE9 G3QHE9 PARP10 PTHR14453:SF94 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP10 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transcription regulator activity#GO:0140110;pentosyltransferase activity#GO:0016763;transcription corepressor activity#GO:0003714;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;glycosyltransferase activity#GO:0016757 regulation of biological process#GO:0050789;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of gene expression#GO:0010629;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000012392.3|UniProtKB=G3R9K4 G3R9K4 PYHIN1 PTHR12200:SF25 INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER PYRIN AND HIN DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;immune system process#GO:0002376;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of response to biotic stimulus#GO:0002831;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;positive regulation of response to external stimulus#GO:0032103;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;response to cytokine#GO:0034097;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000000770.3|UniProtKB=A0A2I2Y7H1 A0A2I2Y7H1 KRTDAP PTHR36463:SF1 KERATINOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN KERATINOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN tissue development#GO:0009888;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;epidermis development#GO:0008544 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015862.3|UniProtKB=G3RIH1 G3RIH1 RPF1 PTHR22734:SF3 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 RIBOSOME PRODUCTION FACTOR 1 RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000040870.1|UniProtKB=G3RVK2 G3RVK2 PTHR20981:SF24 60S RIBOSOMAL PROTEIN L21 60S RIBOSOMAL PROTEIN L21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003780.3|UniProtKB=G3QMH2 G3QMH2 PTHR12223:SF36 VESICULAR MANNOSE-BINDING LECTIN VESICULAR INTEGRAL-MEMBRANE PROTEIN VIP36 carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029;small molecule binding#GO:0036094;binding#GO:0005488 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000034920.2|UniProtKB=G3SKT8 G3SKT8 EPHA6 PTHR46877:SF10 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 6 catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411 dendrite#GO:0030425;dendritic tree#GO:0097447;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011510.3|UniProtKB=G3R798 G3R798 MAP9 PTHR14739:SF9 MICROTUBULE-ASSOCIATED PROTEIN 9 MICROTUBULE-ASSOCIATED PROTEIN 9 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;regulation of cell cycle#GO:0051726;mitotic spindle organization#GO:0007052;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;regulation of cytokinesis#GO:0032465;nuclear division#GO:0000280;biological regulation#GO:0065007;regulation of mitotic cytokinesis#GO:1902412;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;regulation of cell division#GO:0051302 intracellular organelle#GO:0043229;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoplasmic microtubule#GO:0005881;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000015542.3|UniProtKB=G3RHN5 G3RHN5 SVIP PTHR35269:SF1 SMALL VCP/P97-INTERACTING PROTEIN SMALL VCP_P97-INTERACTING PROTEIN regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;regulation of protein metabolic process#GO:0051246;positive regulation of autophagy#GO:0010508;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;regulation of protein localization#GO:0032880;regulation of protein transport#GO:0051223;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of protein transport#GO:0051224;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein catabolic process#GO:0042176;regulation of establishment of protein localization#GO:0070201;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transport#GO:0051051;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of ERAD pathway#GO:1904292;negative regulation of cellular component organization#GO:0051129;regulation of response to endoplasmic reticulum stress#GO:1905897 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000026782.2|UniProtKB=G3RX92 G3RX92 GNG5 PTHR13809:SF51 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT G PROTEIN SUBUNIT GAMMA 5 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;catalytic complex#GO:1902494;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234 heterotrimeric G-protein#PC00117 Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751 GORGO|Ensembl=ENSGGOG00000000502.3|UniProtKB=G3QE12 G3QE12 TRIP11 PTHR18921:SF2 MYOSIN HEAVY CHAIN - RELATED THYROID RECEPTOR-INTERACTING PROTEIN 11 small GTPase binding#GO:0031267;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 cellular process#GO:0009987;Golgi organization#GO:0007030;establishment of localization in cell#GO:0051649;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 actin binding motor protein#PC00040;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000040320.1|UniProtKB=A0A2I2Z1N3 A0A2I2Z1N3 PPP1R9A PTHR16154:SF22 NEURABIN NEURABIN-1 molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-membrane adaptor activity#GO:0043495;protein-containing complex binding#GO:0044877 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neurogenesis#GO:0022008;calcium-mediated signaling#GO:0019722;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;neuron projection development#GO:0031175;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;cytoskeleton organization#GO:0007010;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;dendrite#GO:0030425;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;actin-based cell projection#GO:0098858;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279 GORGO|Ensembl=ENSGGOG00000007081.3|UniProtKB=G3QVY8 G3QVY8 NAA80 PTHR11769:SF19 HYALURONIDASE HYALURONIDASE-3 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;glycosaminoglycan catabolic process#GO:0006027;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026 acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000001664.3|UniProtKB=G3SCB5 G3SCB5 LOC101137392 PTHR11736:SF84 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN C2 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026517.2|UniProtKB=G3SHT7 G3SHT7 C9H11orf42 PTHR36872:SF1 GENE 5901-RELATED GENE 5901-RELATED 9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000003713.3|UniProtKB=G3QMC5 G3QMC5 YEATS2 PTHR23195:SF7 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 2 histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000008454.3|UniProtKB=A0A2I2YPC2 A0A2I2YPC2 DCK PTHR10513:SF19 DEOXYNUCLEOSIDE KINASE DEOXYCYTIDINE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;deoxynucleoside kinase activity#GO:0019136;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000011557.3|UniProtKB=G3R7E1 G3R7E1 SLC8A2 PTHR11878:SF8 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 2 antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;sodium ion transport#GO:0006814;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873 cell junction#GO:0030054;postsynaptic membrane#GO:0045211;axon#GO:0030424;synaptic membrane#GO:0097060;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;membrane#GO:0016020;neuron projection#GO:0043005;presynapse#GO:0098793;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000026364.2|UniProtKB=G3SIJ5 G3SIJ5 PRDX3 PTHR10681:SF182 THIOREDOXIN PEROXIDASE THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular process#GO:0009987;response to stress#GO:0006950;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to oxidative stress#GO:0006979;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016216.3|UniProtKB=G3RJE2 G3RJE2 EIF2AK1 PTHR11042:SF160 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000043964.1|UniProtKB=A0A2I2YNV6 A0A2I2YNV6 PTHR11715:SF23 GLYCINE CLEAVAGE SYSTEM H PROTEIN GLYCINE CLEAVAGE SYSTEM H PROTEIN, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000000110.3|UniProtKB=A0A2I2Y2Q0 A0A2I2Y2Q0 CHRD PTHR46526:SF1 CHORDIN CHORDIN cytokine binding#GO:0019955;protein binding#GO:0005515;binding#GO:0005488 negative regulation of BMP signaling pathway#GO:0030514;multicellular organism development#GO:0007275;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regionalization#GO:0003002;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of BMP signaling pathway#GO:0030510;negative regulation of cell communication#GO:0010648;anatomical structure development#GO:0048856;regulation of signaling#GO:0023051;pattern specification process#GO:0007389;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;dorsal/ventral pattern formation#GO:0009953;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DPP signaling pathway#P06213>SOG#P06293;DPP-SCW signaling pathway#P06212>SOG#P06266;BMP/activin signaling pathway-drosophila#P06211>SOG#P06252;SCW signaling pathway#P06216>SOG#P06335 GORGO|Ensembl=ENSGGOG00000016518.3|UniProtKB=G3RK53 G3RK53 CSRNP3 PTHR13580:SF13 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN 3 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000003464.3|UniProtKB=G3QLP5 G3QLP5 PTHR22879:SF14 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 2A-RELATED GORGO|Ensembl=ENSGGOG00000001640.3|UniProtKB=G3QH03 G3QH03 PTHR11267:SF32 T-BOX PROTEIN-RELATED MAX GENE-ASSOCIATED PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 GORGO|Ensembl=ENSGGOG00000010195.3|UniProtKB=A0A2I2Z4B8 A0A2I2Z4B8 PRRC1 PTHR23276:SF2 PROTEIN PRRC1 PROTEIN PRRC1 protein kinase A regulatory subunit binding#GO:0034237;protein kinase A binding#GO:0051018;binding#GO:0005488;protein binding#GO:0005515 anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000012307.3|UniProtKB=G3SF06 G3SF06 SHROOM1 PTHR15012:SF39 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;actin cytoskeleton organization#GO:0030036;cell morphogenesis#GO:0000902;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;apical junction complex#GO:0043296;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;cell junction#GO:0030054;membraneless organelle#GO:0043228;adherens junction#GO:0005912;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000012212.3|UniProtKB=G3R945 G3R945 EWSR1 PTHR23238:SF3 RNA BINDING PROTEIN RNA-BINDING PROTEIN EWS transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004347.3|UniProtKB=A0A2I2Y3F0 A0A2I2Y3F0 UCHL5 PTHR10589:SF51 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of chromosome organization#GO:0033044;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000017074.3|UniProtKB=G3SC55 G3SC55 KNTC1 PTHR15688:SF1 KINETOCHORE-ASSOCIATED PROTEIN 1 KINETOCHORE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488;enzyme binding#GO:0019899 intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;organelle fission#GO:0048285;negative regulation of chromosome organization#GO:2001251;organelle assembly#GO:0070925;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;intracellular protein localization#GO:0008104;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of mitotic cell cycle#GO:0007346;macromolecule localization#GO:0033036;mitotic sister chromatid segregation#GO:0000070;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;kinetochore assembly#GO:0051382;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;negative regulation of cell cycle#GO:0045786;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;mitotic spindle assembly checkpoint signaling#GO:0007094;regulation of mitotic sister chromatid segregation#GO:0033047;kinetochore organization#GO:0051383;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;protein localization to kinetochore#GO:0034501;nuclear division#GO:0000280;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;protein-containing complex assembly#GO:0065003;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of sister chromatid segregation#GO:0033046 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;microtubule#GO:0005874;spindle microtubule#GO:0005876;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000036857.1|UniProtKB=A0A2I2Z843 A0A2I2Z843 PTHR15415:SF7 MITOFILIN MICOS COMPLEX SUBUNIT MIC60 GORGO|Ensembl=ENSGGOG00000007373.3|UniProtKB=G3QWQ3 G3QWQ3 INPP5K PTHR11200:SF117 INOSITOL 5-PHOSPHATASE INOSITOL POLYPHOSPHATE 5-PHOSPHATASE K phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;negative regulation of cell communication#GO:0010648;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of polysaccharide metabolic process#GO:0032881;negative regulation of signal transduction#GO:0009968;regulation of carbohydrate metabolic process#GO:0006109;negative regulation of cellular process#GO:0048523;regulation of glycogen biosynthetic process#GO:0005979;regulation of response to stimulus#GO:0048583;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;ruffle#GO:0001726;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000014989.3|UniProtKB=G3RS37 G3RS37 AKNAD1 PTHR21510:SF16 AKNA DOMAIN-CONTAINING PROTEIN PROTEIN AKNAD1 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 GORGO|Ensembl=ENSGGOG00000023707.2|UniProtKB=G3RUG4 G3RUG4 RAB10 PTHR47980:SF87 LD44762P RAS-RELATED PROTEIN RAB-10 export from cell#GO:0140352;endocytic recycling#GO:0032456;localization within membrane#GO:0051668;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;exocytosis#GO:0006887;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000012849.3|UniProtKB=G3RAQ7 G3RAQ7 PRSS38 PTHR24253:SF159 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 42 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012703.3|UniProtKB=G3RAD1 G3RAD1 RAP1GAP2 PTHR15711:SF17 RAP GTPASE-ACTIVATING PROTEIN RAP1 GTPASE-ACTIVATING PROTEIN 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;axon#GO:0030424 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000007196.3|UniProtKB=A0A2I2ZAU0 A0A2I2ZAU0 PTHR23324:SF84 SEC14 RELATED PROTEIN SEC14 LIKE LIPID BINDING 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000023037.2|UniProtKB=G3RT90 G3RT90 PTHR11842:SF12 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 HORMA DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;negative regulation of chromosome segregation#GO:0051985;negative regulation of cell cycle#GO:0045786;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic cell cycle#GO:0007346;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of chromosome organization#GO:2001251;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;cell communication#GO:0007154 membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776 GORGO|Ensembl=ENSGGOG00000023428.2|UniProtKB=G3RRU9 G3RRU9 OR10AG1 PTHR26453:SF159 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10AG1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027167.2|UniProtKB=G3SIR7 G3SIR7 PTHR12604:SF8 KU AUTOANTIGEN DNA HELICASE KU DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;telomeric repeat DNA binding#GO:0042162;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;telomere organization#GO:0032200;cellular response to stress#GO:0033554 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA helicase#PC00011 GORGO|Ensembl=ENSGGOG00000012501.3|UniProtKB=G3R9U5 G3R9U5 ANAPC15 PTHR22526:SF4 ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED ANAPHASE-PROMOTING COMPLEX SUBUNIT 15 regulation of sister chromatid segregation#GO:0033045;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of chromosome separation#GO:1905818;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;regulation of response to stimulus#GO:0048583;regulation of chromosome segregation#GO:0051983;regulation of chromosome organization#GO:0033044 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000007024.3|UniProtKB=G3QVT7 G3QVT7 IBSP PTHR10345:SF0 BONE SIALOPROTEIN 2 INTEGRIN-BINDING SIALOPROTEIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 tissue development#GO:0009888;multicellular organismal process#GO:0032501;ossification#GO:0001503;cellular process#GO:0009987;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;animal organ development#GO:0048513;biomineral tissue development#GO:0031214;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;bone mineralization#GO:0030282 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000042043.1|UniProtKB=A0A2I2Y5C6 A0A2I2Y5C6 PTHR21399:SF4 CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN METHYLOSOME SUBUNIT PICLN cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003 spliceosomal complex#GO:0005681;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010361.3|UniProtKB=G3RQ08 G3RQ08 TRAF3IP1 PTHR31363:SF0 TRAF3-INTERACTING PROTEIN 1 TRAF3-INTERACTING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular localization#GO:0051641;cilium organization#GO:0044782;microtubule-based transport#GO:0099111;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;localization#GO:0051179;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;intraciliary transport#GO:0042073 membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intraciliary transport particle B#GO:0030992;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000027711.2|UniProtKB=G3S777 G3S777 GGTLC1 PTHR45027:SF4 PUTATIVE GLUTATHIONE HYDROLASE LIGHT CHAIN GLUTATHIONE HYDROLASE LIGHT CHAIN 1 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000013965.3|UniProtKB=G3RDL2 G3RDL2 PSMG3 PTHR31051:SF1 PROTEASOME ASSEMBLY CHAPERONE 3 PROTEASOME ASSEMBLY CHAPERONE 3 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000039812.1|UniProtKB=A0A2I2YLU1 A0A2I2YLU1 LOC109027573 PTHR12416:SF8 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN FCF1 HOMOLOG RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040 GORGO|Ensembl=ENSGGOG00000000483.3|UniProtKB=G3QDZ2 G3QDZ2 OGFOD2 PTHR24014:SF4 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015714.3|UniProtKB=G3RI48 G3RI48 RAB4A PTHR47979:SF73 DRAB11-RELATED RAS-RELATED PROTEIN RAB-4A purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167 cellular process#GO:0009987;regulation of biological process#GO:0050789;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;transport#GO:0006810;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;localization#GO:0051179 recycling endosome#GO:0055037;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000038139.1|UniProtKB=A0A2I2ZU82 A0A2I2ZU82 RD3L PTHR28489:SF3 RENTINAL DEGENERATION 3-LIKE PROTEIN RD3-LIKE GORGO|Ensembl=ENSGGOG00000015603.3|UniProtKB=G3RHU8 G3RHU8 MVP PTHR14165:SF3 MAJOR VAULT PROTEIN MAJOR VAULT PROTEIN cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006322.3|UniProtKB=G3QTZ9 G3QTZ9 HNF1B PTHR11568:SF2 HEPATOCYTE NUCLEAR FACTOR 1 HEPATOCYTE NUCLEAR FACTOR 1-BETA RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000043189.1|UniProtKB=A0A2I2YX34 A0A2I2YX34 TM2D2 PTHR21016:SF4 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of Notch signaling pathway#GO:0045747;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056 GORGO|Ensembl=ENSGGOG00000004713.3|UniProtKB=A0A2I2ZUM8 A0A2I2ZUM8 PAM16 PTHR12388:SF0 MITOCHONDRIA ASSOCIATED GRANULOCYTE MACROPHAGE CSF SIGNALING MOLECULE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM16 protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016978.3|UniProtKB=G3RLC5 G3RLC5 EMC8 PTHR12941:SF13 ER MEMBRANE PROTEIN COMPLEX ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 GORGO|Ensembl=ENSGGOG00000000145.3|UniProtKB=G3QD40 G3QD40 CDH3 PTHR24027:SF446 CADHERIN-23 CADHERIN-3 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell migration#GO:0016477;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622 cadherin#PC00057;cell adhesion molecule#PC00069 Alzheimer disease-presenilin pathway#P00004>E-cadherin transmembrane fragment#P00139;Wnt signaling pathway#P00057>Cadherin#P01440;Alzheimer disease-presenilin pathway#P00004>E-cadherin#P00118;Alzheimer disease-presenilin pathway#P00004>E-cadherin intracellular fragment#P00168;Alzheimer disease-presenilin pathway#P00004>E-cadherin C-terminal fragment#P00117;Alzheimer disease-presenilin pathway#P00004>E-cadherin N-terminal fragment#P00165;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000005931.3|UniProtKB=G3QT04 G3QT04 JAML PTHR13869:SF22 MYELIN P0 RELATED JUNCTIONAL ADHESION MOLECULE-LIKE cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000016565.3|UniProtKB=G3RWJ6 G3RWJ6 TTC21A PTHR14699:SF2 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21A macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;transport#GO:0006810;flagellated sperm motility#GO:0030317;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;protein localization to cilium#GO:0061512;intraciliary transport#GO:0042073;reproductive process#GO:0022414;protein localization to organelle#GO:0033365;microtubule-based movement#GO:0007018;cell motility#GO:0048870;sexual reproduction#GO:0019953;spermatid development#GO:0007286;multicellular organismal reproductive process#GO:0048609;localization#GO:0051179;anatomical structure development#GO:0048856;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;sperm motility#GO:0097722;cellular component organization#GO:0016043;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;intraciliary retrograde transport#GO:0035721;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based transport#GO:0099111;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;cellular localization#GO:0051641 protein-containing complex#GO:0032991;intraciliary transport particle A#GO:0030991;intraciliary transport particle#GO:0030990 GORGO|Ensembl=ENSGGOG00000009595.3|UniProtKB=G3R2C5 G3R2C5 LOC101135980 PTHR48043:SF137 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2A3 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 GORGO|Ensembl=ENSGGOG00000017064.3|UniProtKB=G3RLK2 G3RLK2 NSDHL PTHR10366:SF860 NAD DEPENDENT EPIMERASE/DEHYDRATASE STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 secondary alcohol metabolic process#GO:1902652;steroid metabolic process#GO:0008202;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydratase#PC00091;lyase#PC00144;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000005670.3|UniProtKB=A0A2I2YFB5 A0A2I2YFB5 IL4 PTHR47401:SF3 INTERLEUKIN-4 INTERLEUKIN-4 cell surface receptor signaling pathway#GO:0007166;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of response to external stimulus#GO:0032102;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;cytokine-mediated signaling pathway#GO:0019221;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716 interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970 GORGO|Ensembl=ENSGGOG00000007652.3|UniProtKB=G3RW86 G3RW86 CD47 PTHR10613:SF0 LEUKOCYTE SURFACE ANTIGEN CD47 LEUKOCYTE SURFACE ANTIGEN CD47 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000042955.1|UniProtKB=A0A2I2Y9Q5 A0A2I2Y9Q5 PTHR23266:SF379 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-3 binding#GO:0005488;antigen binding#GO:0003823 immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000003471.3|UniProtKB=G3SAV9 G3SAV9 KRT77 PTHR45616:SF24 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 1B structural molecule activity#GO:0005198 intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;epidermis development#GO:0008544;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;skin development#GO:0043588;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000007985.3|UniProtKB=G3QY89 G3QY89 FGD1 PTHR12673:SF79 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;filopodium assembly#GO:0046847;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000012436.3|UniProtKB=A0A2I2ZG96 A0A2I2ZG96 ARL15 PTHR46693:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 GORGO|Ensembl=ENSGGOG00000015744.3|UniProtKB=A0A2I2YM55 A0A2I2YM55 PTPN9 PTHR19134:SF285 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 9 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006252.3|UniProtKB=G3QTT1 G3QTT1 MEOX2 PTHR24328:SF1 HOMEOBOX PROTEIN MOX HOMEOBOX PROTEIN MOX-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000027419.2|UniProtKB=G3RVI9 G3RVI9 NXNL2 PTHR46762:SF1 NUCLEOREDOXIN-LIKE PROTEIN 2 NUCLEOREDOXIN-LIKE PROTEIN 2 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;visual perception#GO:0007601 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000026878.2|UniProtKB=G3S6N7 G3S6N7 MKLN1 PTHR15526:SF5 MUSKELIN MUSKELIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000006695.3|UniProtKB=G3QUY9 G3QUY9 COL6A5 PTHR22588:SF4 VWFA DOMAIN-CONTAINING PROTEIN COLLAGEN ALPHA-5(VI) CHAIN external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 GORGO|Ensembl=ENSGGOG00000009106.3|UniProtKB=G3R152 G3R152 CNPY2 PTHR13341:SF6 MIR-INTERACTING SAPOSIN-LIKE PROTEIN PROTEIN CANOPY HOMOLOG 2 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000011000.3|UniProtKB=G3R5Y7 G3R5Y7 PPM1G PTHR13832:SF872 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1G catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000001523.3|UniProtKB=G3QGP3 G3QGP3 CCNB1 PTHR10177:SF193 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887 cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;chromosome localization#GO:0050000;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;organelle fission#GO:0048285;localization#GO:0051179;organelle localization#GO:0051640;nuclear division#GO:0000280;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic metaphase chromosome alignment#GO:0007080 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;protein kinase complex#GO:1902911;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554 kinase activator#PC00138 p53 pathway#P00059>Cyclin B#P04614;Cell cycle#P00013>Cyclin B#P00486 GORGO|Ensembl=ENSGGOG00000000673.3|UniProtKB=A0A2I2YXP4 A0A2I2YXP4 SAMD4A PTHR12515:SF8 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG HOMOLOG 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000022941.2|UniProtKB=A0A2I2Z118 A0A2I2Z118 PTHR23043:SF30 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015972.3|UniProtKB=G3RIT5 G3RIT5 ABCC8 PTHR24223:SF187 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000043511.1|UniProtKB=A0A2I2ZEZ1 A0A2I2ZEZ1 PTHR24055:SF171 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 6 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell surface receptor signaling pathway#GO:0007166 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>MEK#P01402;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interleukin signaling pathway#P00036>ERK#P00965;Integrin signalling pathway#P00034>ERK#P00907 GORGO|Ensembl=ENSGGOG00000004070.3|UniProtKB=G3QN85 G3QN85 SLAMF6 PTHR12080:SF16 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;T cell activation#GO:0042110;cell communication#GO:0007154;cell activation#GO:0001775;immune system process#GO:0002376 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000042023.1|UniProtKB=A0A2I2Z3V8 A0A2I2Z3V8 PTHR12623:SF9 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 GORGO|Ensembl=ENSGGOG00000017153.3|UniProtKB=G3RYB4 G3RYB4 CD72 PTHR15028:SF10 CD72-RELATED B-CELL DIFFERENTIATION ANTIGEN CD72 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of B cell receptor signaling pathway#GO:0050855;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000010909.3|UniProtKB=G3R5Q1 G3R5Q1 TUBA3E PTHR11588:SF322 TUBULIN TUBULIN ALPHA-3C CHAIN-RELATED structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265 cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;tubulin#PC00228 GORGO|Ensembl=ENSGGOG00000002722.3|UniProtKB=G3RW65 G3RW65 RGCC PTHR32193:SF3 REGULATOR OF CELL CYCLE RGCC REGULATOR OF CELL CYCLE RGCC protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 positive regulation of mitotic cell cycle#GO:0045931;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;regulation of mitotic cell cycle#GO:0007346;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of immune response#GO:0050776;response to transforming growth factor beta#GO:0071559;regulation of cell cycle G1/S phase transition#GO:1902806;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;positive regulation of immune system process#GO:0002684;cellular response to growth factor stimulus#GO:0071363;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;immune system process#GO:0002376;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to endogenous stimulus#GO:0009719 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000002293.3|UniProtKB=G3QIP3 G3QIP3 CRY2 PTHR11455:SF15 CRYPTOCHROME CRYPTOCHROME-2 carbon-carbon lyase activity#GO:0016830;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotide binding#GO:0000166;anion binding#GO:0043168;deoxyribodipyrimidine photo-lyase activity#GO:0003904;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;ion binding#GO:0043167;DNA binding#GO:0003677 circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;rhythmic process#GO:0048511;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;circadian regulation of gene expression#GO:0032922;negative regulation of biological process#GO:0048519;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;photoperiodism#GO:0009648;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to radiation#GO:0009314;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505;Circadian clock system#P00015>cry#G01501;Circadian clock system#P00015>cry#G01497 GORGO|Ensembl=ENSGGOG00000041260.1|UniProtKB=A0A2I2YAZ7 A0A2I2YAZ7 TMEM236 PTHR31453:SF2 TRANSMEMBRANE PROTEIN 236 TRANSMEMBRANE PROTEIN 236 GORGO|Ensembl=ENSGGOG00000009506.3|UniProtKB=G3R247 G3R247 CLEC3A PTHR22799:SF2 TETRANECTIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 3 MEMBER A multicellular organismal process#GO:0032501;ossification#GO:0001503 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000003495.3|UniProtKB=G3QLS1 G3QLS1 PPP2R2C PTHR11871:SF5 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B GAMMA ISOFORM protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 GORGO|Ensembl=ENSGGOG00000003765.3|UniProtKB=A0A2I2YLD7 A0A2I2YLD7 SLC39A14 PTHR12191:SF5 SOLUTE CARRIER FAMILY 39 METAL CATION SYMPORTER ZIP14 transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000012810.3|UniProtKB=G3S4F3 G3S4F3 CTNNA1 PTHR18914:SF24 ALPHA CATENIN CATENIN ALPHA-1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;beta-catenin binding#GO:0008013;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 cell motility#GO:0048870;cell migration#GO:0016477;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161 non-motor actin binding protein#PC00165 Wnt signaling pathway#P00057>alpha-catenin#P01471;Alzheimer disease-presenilin pathway#P00004>alpha-catenin#P00133;Cadherin signaling pathway#P00012>alpha-catenin#P00467 GORGO|Ensembl=ENSGGOG00000008138.3|UniProtKB=G3QYL2 G3QYL2 ACSM3 PTHR43605:SF7 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM3, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;purine-containing compound metabolic process#GO:0072521;oxoacid metabolic process#GO:0043436 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;ligase#PC00142 GORGO|Ensembl=ENSGGOG00000004222.3|UniProtKB=G3QNM4 G3QNM4 ABITRAM PTHR13651:SF1 PROTEIN ABITRAM PROTEIN ABITRAM cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;actin monomer binding#GO:0003785;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;generation of neurons#GO:0048699;dendrite development#GO:0016358;regulation of biological quality#GO:0065008;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399;regulation of anatomical structure size#GO:0090066;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;dendrite morphogenesis#GO:0048813;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;anatomical structure development#GO:0048856;regulation of cell projection assembly#GO:0060491;system development#GO:0048731;regulation of actin filament organization#GO:0110053;multicellular organismal process#GO:0032501;regulation of actin filament polymerization#GO:0030833;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;regulation of filopodium assembly#GO:0051489 intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;nucleus#GO:0005634;neuron projection#GO:0043005;cell leading edge#GO:0031252;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;lamellipodium#GO:0030027 GORGO|Ensembl=ENSGGOG00000012434.3|UniProtKB=G3R9P2 G3R9P2 TIMM10 PTHR11038:SF16 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 mitochondrial transport#GO:0006839;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;membrane organization#GO:0061024;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrial protein import pathway#GO:7770058;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular transport#GO:0046907;transport#GO:0006810 organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024374.2|UniProtKB=G3SGK7 G3SGK7 COMMD8 PTHR16231:SF0 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 8 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to peptide#GO:1901652;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;signal transduction#GO:0007165;cellular process#GO:0009987;response to tumor necrosis factor#GO:0034612;cell surface receptor signaling pathway#GO:0007166 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000015030.4|UniProtKB=A0A2I2YB40 A0A2I2YB40 TEX9 PTHR23313:SF0 TSEC1-RELATED TESTIS-EXPRESSED PROTEIN 9 actin binding motor protein#PC00040;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000006749.3|UniProtKB=G3QV51 G3QV51 FLT4 PTHR24416:SF49 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of locomotion#GO:0040017;positive regulation of MAPK cascade#GO:0043410;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;tube development#GO:0035295;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell migration#GO:0016477;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;sprouting angiogenesis#GO:0002040;positive regulation of signaling#GO:0023056;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;vascular endothelial growth factor receptor signaling pathway#GO:0048010;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 GORGO|Ensembl=ENSGGOG00000008305.3|UniProtKB=G3QZ16 G3QZ16 LRRC55 PTHR46473:SF5 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 55 molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;channel activity#GO:0015267;channel regulator activity#GO:0016247;potassium ion transmembrane transporter activity#GO:0015079;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;transmembrane transporter binding#GO:0044325;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;molecular function activator activity#GO:0140677;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;potassium channel regulator activity#GO:0015459;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 GORGO|Ensembl=ENSGGOG00000000030.3|UniProtKB=G3QCT3 G3QCT3 MCAT PTHR42681:SF8 MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000010414.3|UniProtKB=G3R4G8 G3R4G8 DDX54 PTHR24031:SF292 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX54 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000016607.3|UniProtKB=G3RKD7 G3RKD7 FMO3 PTHR23023:SF44 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE 3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity#GO:0016491 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987;biosynthetic process#GO:0009058 oxygenase#PC00177;oxidoreductase#PC00176 Nicotine degradation#P05914>FMO3#P05979 GORGO|Ensembl=ENSGGOG00000008678.3|UniProtKB=G3R012 G3R012 CD6 PTHR19331:SF477 SCAVENGER RECEPTOR DOMAIN-CONTAINING T-CELL DIFFERENTIATION ANTIGEN CD6 cargo receptor activity#GO:0038024 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000009738.3|UniProtKB=G3R2Q2 G3R2Q2 ANXA2 PTHR10502:SF18 ANNEXIN ANNEXIN A2-RELATED ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786 regulation of proteolysis#GO:0030162;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of protein metabolic process#GO:0051247;cell adhesion#GO:0007155;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000016491.3|UniProtKB=G3RK34 G3RK34 SLC9A2 PTHR10110:SF89 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 2 potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000008101.3|UniProtKB=G3RTV3 G3RTV3 OVOL1 PTHR10032:SF217 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS TRANSCRIPTION FACTOR OVO-LIKE 1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;epidermis development#GO:0008544;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000001269.3|UniProtKB=G3QG06 G3QG06 DALRD3 PTHR16043:SF1 DALRD3 PROTEIN DALR ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA binding#GO:0000049;RNA binding#GO:0003723 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 GORGO|Ensembl=ENSGGOG00000006839.3|UniProtKB=A0A2I2Y5K9 A0A2I2Y5K9 SLC38A6 PTHR22950:SF366 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 38 MEMBER 6 neutral L-amino acid transmembrane transporter activity#GO:0015175;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 localization#GO:0051179;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 GORGO|Ensembl=ENSGGOG00000016619.3|UniProtKB=G3RNK3 G3RNK3 LOC101145974 PTHR11468:SF3 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, LIVER FORM glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate catabolic process#GO:0016052;energy reserve metabolic process#GO:0006112;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;polysaccharide catabolic process#GO:0000272;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;generation of precursor metabolites and energy#GO:0006091;glycogen catabolic process#GO:0005980;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 GORGO|Ensembl=ENSGGOG00000037117.1|UniProtKB=G3RX39 G3RX39 PTHR14744:SF15 N-ALPHA-ACETYLTRANSFERASE 60 N-ALPHA-ACETYLTRANSFERASE 60 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;N-acetyltransferase activity#GO:0008080;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186 cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;chromosome segregation#GO:0007059 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 acetyltransferase#PC00038;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000015949.3|UniProtKB=G3SDW9 G3SDW9 ANKRD12 PTHR24149:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 GORGO|Ensembl=ENSGGOG00000006661.3|UniProtKB=G3QUV9 G3QUV9 ACVRL1 PTHR23255:SF66 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1-LIKE transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;pattern specification process#GO:0007389;response to transforming growth factor beta#GO:0071559;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;dorsal/ventral pattern formation#GO:0009953;cellular response to transforming growth factor beta stimulus#GO:0071560;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;BMP signaling pathway#GO:0030509;cellular developmental process#GO:0048869;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;tube development#GO:0035295;multicellular organismal process#GO:0032501;regionalization#GO:0003002;cellular response to growth factor stimulus#GO:0071363;angiogenesis#GO:0001525;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;circulatory system development#GO:0072359;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;blood vessel morphogenesis#GO:0048514;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;signaling receptor complex#GO:0043235 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 GORGO|Ensembl=ENSGGOG00000010741.3|UniProtKB=G3R5B1 G3R5B1 CD96 PTHR15317:SF1 T-CELL SURFACE PROTEIN TACTILE T-CELL SURFACE PROTEIN TACTILE cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000026774.2|UniProtKB=G3S2K0 G3S2K0 LOC101127555 PTHR11071:SF490 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000042246.1|UniProtKB=A0A2I2ZK59 A0A2I2ZK59 C1H1orf210 PTHR31450:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 LRRC19 FAMILY MEMBER TYPE III ENDOSOME MEMBRANE PROTEIN TEMP GORGO|Ensembl=ENSGGOG00000001350.3|UniProtKB=G3QG81 G3QG81 FAM200A PTHR45935:SF1 PROTEIN ZBED8-RELATED PROTEIN FAM200A GORGO|Ensembl=ENSGGOG00000009627.3|UniProtKB=G3SDX5 G3SDX5 PTHR24369:SF9 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4 protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 intracellular protein localization#GO:0008104;developmental process#GO:0032502;biological regulation#GO:0065007;membrane organization#GO:0061024;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036;system development#GO:0048731;postsynaptic specialization organization#GO:0099084;localization#GO:0051179;anatomical structure development#GO:0048856;synapse organization#GO:0050808;localization within membrane#GO:0051668;modulation of chemical synaptic transmission#GO:0050804;postsynapse organization#GO:0099173;regulation of cell communication#GO:0010646;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;nervous system development#GO:0007399;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;cellular localization#GO:0051641;cell adhesion#GO:0007155;postsynaptic density organization#GO:0097106;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;excitatory synapse assembly#GO:1904861;synapse assembly#GO:0007416;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000016264.3|UniProtKB=G3RJI1 G3RJI1 SOX5 PTHR45789:SF3 FI18025P1 TRANSCRIPTION FACTOR SOX-5 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;regulation of developmental process#GO:0050793;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000005200.3|UniProtKB=G3RTX7 G3RTX7 DNAJA2 PTHR43888:SF31 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 2 ATPase activator activity#GO:0001671;protein binding#GO:0005515;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 response to stimulus#GO:0050896;protein folding#GO:0006457;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;protein refolding#GO:0042026;cellular response to stress#GO:0033554;gene expression#GO:0010467;protein maturation#GO:0051604;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;response to stress#GO:0006950;cellular response to heat#GO:0034605;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000008621.3|UniProtKB=G3SFY9 G3SFY9 PDCD10 PTHR13250:SF1 TF-1 CELL APOPTOSIS RELATED PROTEIN-15 PROGRAMMED CELL DEATH PROTEIN 10 protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000016421.3|UniProtKB=G3RJX1 G3RJX1 TRIM63 PTHR24103:SF570 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM63 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000041742.1|UniProtKB=A0A2I2YBM2 A0A2I2YBM2 SLC6A8 PTHR11616:SF96 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 GORGO|Ensembl=ENSGGOG00000007955.3|UniProtKB=G3QY61 G3QY61 TRAP1 PTHR11528:SF44 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 75 KDA, MITOCHONDRIAL-RELATED nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp90 family chaperone#PC00028 GORGO|Ensembl=ENSGGOG00000034970.2|UniProtKB=A0A2I2Z0B2 A0A2I2Z0B2 LYRM4 PTHR13166:SF7 PROTEIN C6ORF149 LYR MOTIF-CONTAINING PROTEIN 4 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;sulfurtransferase complex#GO:1990228;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000036663.1|UniProtKB=A0A2I2ZCC9 A0A2I2ZCC9 PRSS22 PTHR24253:SF6 TRANSMEMBRANE PROTEASE SERINE BRAIN-SPECIFIC SERINE PROTEASE 4 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000000436.3|UniProtKB=G3SJ20 G3SJ20 SNAP91 PTHR22951:SF4 CLATHRIN ASSEMBLY PROTEIN CLATHRIN COAT ASSEMBLY PROTEIN AP180 binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;phospholipid binding#GO:0005543;clathrin binding#GO:0030276;SNARE binding#GO:0000149;phosphatidylinositol phosphate binding#GO:1901981 cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583 organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;clathrin-coated vesicle#GO:0030136;synaptic membrane#GO:0097060 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000000570.3|UniProtKB=G3QE72 G3QE72 TPD52L2 PTHR19307:SF13 TUMOR PROTEIN D52 TUMOR PROTEIN D54 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003505.3|UniProtKB=G3QLT5 G3QLT5 PTHR12269:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013248.3|UniProtKB=G3RBR3 G3RBR3 OSBPL5 PTHR10972:SF213 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 5 small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934;alcohol binding#GO:0043178;cholesterol binding#GO:0015485;steroid binding#GO:0005496;lipid binding#GO:0008289 lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;macromolecule localization#GO:0033036;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;phospholipid transport#GO:0015914 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000026756.2|UniProtKB=G3RQ68 G3RQ68 RADX PTHR14944:SF2 RPA-RELATED PROTEIN RADX RPA-RELATED PROTEIN RADX GORGO|Ensembl=ENSGGOG00000009452.3|UniProtKB=G3R1Z7 G3R1Z7 TSGA10IP PTHR21501:SF5 PROTEIN FAM-161 TESTIS-SPECIFIC PROTEIN 10-INTERACTING PROTEIN cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium organization#GO:0044782;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000038498.1|UniProtKB=A0A2I2ZEN3 A0A2I2ZEN3 PTHR45871:SF4 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000015540.4|UniProtKB=A0A2I2ZAM7 A0A2I2ZAM7 ADAMTS9 PTHR13723:SF33 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 9 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000007645.3|UniProtKB=G3RPB0 G3RPB0 PTHR24118:SF56 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER G-RELATED transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000010390.3|UniProtKB=A0A2I2ZIL1 A0A2I2ZIL1 MED27 PTHR13130:SF4 34 KDA TRANSCRIPTIONAL CO-ACTIVATOR-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 27 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000001554.3|UniProtKB=G3QGS2 G3QGS2 MX2 PTHR11566:SF46 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MX2 hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;microtubule binding#GO:0008017;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787 defense response to virus#GO:0051607;cellular component organization#GO:0016043;response to stimulus#GO:0050896;endocytosis#GO:0006897;establishment of organelle localization#GO:0051656;biological process involved in interspecies interaction between organisms#GO:0044419;cellular localization#GO:0051641;organelle organization#GO:0006996;response to biotic stimulus#GO:0009607;synaptic vesicle transport#GO:0048489;response to stress#GO:0006950;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;vesicle organization#GO:0016050;synaptic vesicle endocytosis#GO:0048488;response to external biotic stimulus#GO:0043207;organelle localization#GO:0051640;localization#GO:0051179;response to virus#GO:0009615;vesicle localization#GO:0051648;synaptic vesicle recycling#GO:0036465;membrane organization#GO:0061024;response to other organism#GO:0051707;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;response to external stimulus#GO:0009605;defense response#GO:0006952;vesicle budding from membrane#GO:0006900 cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;nucleus#GO:0005634;microtubule#GO:0005874;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000038259.1|UniProtKB=A0A2I2ZQ07 A0A2I2ZQ07 MTPN PTHR24189:SF76 MYOTROPHIN MYOTROPHIN regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of actin filament depolymerization#GO:0030834;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of protein-containing complex disassembly#GO:0043244;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of protein depolymerization#GO:1901879;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000037309.1|UniProtKB=A0A2I2ZCN9 A0A2I2ZCN9 PTHR11711:SF147 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5A GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 localization within membrane#GO:0051668;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;protein localization to organelle#GO:0033365;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000002649.3|UniProtKB=G3QJL0 G3QJL0 RGS16 PTHR10845:SF187 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 16 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;negative regulation of cell communication#GO:0010648;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 GORGO|Ensembl=ENSGGOG00000006552.3|UniProtKB=G3QUK4 G3QUK4 VGLL1 PTHR15950:SF20 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 1 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000010981.3|UniProtKB=G3R5X3 G3R5X3 CDH18 PTHR24027:SF106 CADHERIN-23 CADHERIN-18 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell migration#GO:0016477;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;anatomical structure morphogenesis#GO:0009653;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;anatomical structure development#GO:0048856 anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000014941.4|UniProtKB=G3RG49 G3RG49 CTTNBP2 PTHR24166:SF27 ROLLING PEBBLES, ISOFORM B CORTACTIN-BINDING PROTEIN 2 regulation of synapse organization#GO:0050807;regulation of biological process#GO:0050789;regulation of synapse structure or activity#GO:0050803;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005893.3|UniProtKB=G3QSX0 G3QSX0 GDF2 PTHR11848:SF157 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 2 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 positive regulation of epithelial cell proliferation#GO:0050679;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000013440.3|UniProtKB=G3RC84 G3RC84 PTHR26450:SF166 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51D1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015514.3|UniProtKB=G3RHL2 G3RHL2 TMEM252 PTHR35682:SF1 TRANSMEMBRANE PROTEIN 252 TRANSMEMBRANE PROTEIN 252 GORGO|Ensembl=ENSGGOG00000003993.3|UniProtKB=G3QN14 G3QN14 AQP3 PTHR43829:SF7 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-3 water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;carbohydrate transmembrane transporter activity#GO:0015144 carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987;fluid transport#GO:0042044;organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;water transport#GO:0006833;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000041150.1|UniProtKB=A0A2I2ZXY8 A0A2I2ZXY8 PTHR36289:SF1 CHROMOSOME 12 OPEN READING FRAME 60 CHROMOSOME 12 OPEN READING FRAME 60 GORGO|Ensembl=ENSGGOG00000016524.3|UniProtKB=G3S3Y4 G3S3Y4 SLC39A13 PTHR16950:SF16 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER ZIP13 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075 homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002322.3|UniProtKB=G3QIS0 G3QIS0 VMP1 PTHR10281:SF121 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED VACUOLE MEMBRANE PROTEIN 1 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;intramembrane lipid carrier activity#GO:0140303 metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macroautophagy#GO:0016236;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;Golgi organization#GO:0007030;cellular component organization#GO:0016043;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000500.3|UniProtKB=G3QE06 G3QE06 ZNF654 PTHR15507:SF16 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN 654 DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015518.3|UniProtKB=G3RHL5 G3RHL5 MRM3 PTHR43191:SF2 RRNA METHYLTRANSFERASE 3, RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000022591.2|UniProtKB=A0A2I2Z1I4 A0A2I2Z1I4 VPS13A PTHR16166:SF22 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13A lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 lipid localization#GO:0010876;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;cellular component organization#GO:0016043;catabolic process#GO:0009056;transport#GO:0006810;metabolic process#GO:0008152;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagy#GO:0006914;macromolecule localization#GO:0033036;organelle organization#GO:0006996;macroautophagy#GO:0016236;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;lipid transport#GO:0006869 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;outer membrane#GO:0019867;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000042915.1|UniProtKB=A0A2I2Z8I1 A0A2I2Z8I1 PTHR12510:SF4 TROPONIN C-AKIN-1 PROTEIN GAMMA-GLUTAMYLAMINECYCLOTRANSFERASE cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000022770.2|UniProtKB=G3SBY2 G3SBY2 EOLA1 PTHR31666:SF0 PROTEIN CXORF40A-RELATED PROTEIN EOLA1-RELATED GORGO|Ensembl=ENSGGOG00000000355.3|UniProtKB=G3QDM5 G3QDM5 PTHR11216:SF127 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endocytosis#GO:0006897;endocytic recycling#GO:0032456;cell projection organization#GO:0030030;cilium assembly#GO:0060271;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778 cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;recycling endosome#GO:0055037;organelle membrane#GO:0031090;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000022399.2|UniProtKB=A0A2I2ZRM4 A0A2I2ZRM4 PTHR11994:SF26 60S RIBOSOMAL PROTEIN L11-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL5 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009567.3|UniProtKB=G3R2A0 G3R2A0 CDK2AP1 PTHR22607:SF2 DELETED IN ORAL CANCER 1/CDK2-ASSOCIATED PROTEIN 1 CYCLIN-DEPENDENT KINASE 2-ASSOCIATED PROTEIN 1 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase modulator#PC00140;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000041798.1|UniProtKB=A0A2I2ZKH8 A0A2I2ZKH8 PTHR10061:SF0 S-FORMYLGLUTATHIONE HYDROLASE S-FORMYLGLUTATHIONE HYDROLASE hydrolase activity#GO:0016787;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010984.3|UniProtKB=G3R5W4 G3R5W4 CHST2 PTHR10704:SF3 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 2 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 amino sugar metabolic process#GO:0006040;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001919.3|UniProtKB=G3QHQ6 G3QHQ6 STX5 PTHR19957:SF3 SYNTAXIN SYNTAXIN-5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 membrane protein complex#GO:0098796;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 SNARE protein#PC00034 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091 GORGO|Ensembl=ENSGGOG00000014253.3|UniProtKB=G3REB8 G3REB8 PTHR11937:SF194 ACTIN ACTIN-LIKE PROTEIN 9 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;structural constituent of cytoskeleton#GO:0005200;structural constituent of synapse#GO:0098918;protein binding#GO:0005515;structural molecule activity#GO:0005198 neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;cytoskeleton#GO:0005856;transferase complex#GO:1990234;H4 histone acetyltransferase complex#GO:1902562;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;chromosome#GO:0005694;cell junction#GO:0030054;histone acetyltransferase complex#GO:0000123;actin filament#GO:0005884;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;NuA4 histone acetyltransferase complex#GO:0035267;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;neuron projection#GO:0043005;acetyltransferase complex#GO:1902493;supramolecular fiber#GO:0099512;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000004886.3|UniProtKB=G3QQC2 G3QQC2 OR52N1 PTHR26450:SF145 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001513.3|UniProtKB=A0A2I2ZR47 A0A2I2ZR47 NDUFS1 PTHR11615:SF377 NITRATE, FORMATE, IRON DEHYDROGENASE NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;NADH dehydrogenase activity#GO:0003954;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;electron transfer activity#GO:0009055 aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;oxidoreductase complex#GO:1990204;membrane#GO:0016020;organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002848.3|UniProtKB=G3RM87 G3RM87 DPP9 PTHR11731:SF109 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 9 catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000006887.3|UniProtKB=G3QVG5 G3QVG5 C21H20orf173 PTHR46032:SF7 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 RIKEN CDNA 6430550D23 GENE catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000038410.1|UniProtKB=G3SIC3 G3SIC3 PTHR24083:SF98 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1 signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000012738.3|UniProtKB=A0A2I2Z3M3 A0A2I2Z3M3 SCAMP5 PTHR10687:SF5 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 5 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;recycling endosome membrane#GO:0055038;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000014776.3|UniProtKB=G3RFP4 G3RFP4 LIM2 PTHR10671:SF9 EPITHELIAL MEMBRANE PROTEIN-RELATED LENS FIBER MEMBRANE INTRINSIC PROTEIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000014549.3|UniProtKB=G3RF33 G3RF33 TNFSF10 PTHR11471:SF27 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Apoptosis signaling pathway#P00006>TRAIL#P00263 GORGO|Ensembl=ENSGGOG00000005540.3|UniProtKB=A0A2I2ZNV6 A0A2I2ZNV6 TRIR PTHR34753:SF1 TELOMERASE RNA COMPONENT INTERACTING RNASE TELOMERASE RNA COMPONENT-INTERACTING RNASE exonuclease activity#GO:0004527;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000000576.3|UniProtKB=G3QE78 G3QE78 CAB39L PTHR10182:SF9 CALCIUM-BINDING PROTEIN 39-RELATED CALCIUM-BINDING PROTEIN 39-LIKE enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295 GORGO|Ensembl=ENSGGOG00000015153.3|UniProtKB=A0A2I2ZJU4 A0A2I2ZJU4 PI4KB PTHR10048:SF122 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity#GO:0016740;catalytic activity#GO:0003824;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;anatomical structure development#GO:0048856;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;developmental process#GO:0032502;sensory organ development#GO:0007423;biosynthetic process#GO:0009058;biological regulation#GO:0065007;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;inner ear development#GO:0048839;organophosphate metabolic process#GO:0019637;ear development#GO:0043583;animal gross anatomical part developmental process#GO:0160108;phosphatidylinositol phosphate biosynthetic process#GO:0046854;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;animal organ development#GO:0048513;metabolic process#GO:0008152;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000038975.1|UniProtKB=G3RVW6 G3RVW6 LOC101139701 PTHR23262:SF250 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-10 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000026273.2|UniProtKB=G3RUQ4 G3RUQ4 MINAR2 PTHR31530:SF4 MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 MINAR1 FAMILY MEMBER MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1-LIKE transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008588.3|UniProtKB=G3QZT3 G3QZT3 MADD PTHR13008:SF7 MAP-KINASE ACTIVATING DEATH DOMAIN PROTEIN MADD /DENN/AEX-3 C.ELEGANS MAP KINASE-ACTIVATING DEATH DOMAIN PROTEIN molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 Apoptosis signaling pathway#P00006>MADD#P00267 GORGO|Ensembl=ENSGGOG00000026460.2|UniProtKB=G3RSP8 G3RSP8 PPFIA2 PTHR12587:SF6 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-2 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808 cellular anatomical structure#GO:0110165;synapse#GO:0045202;presynaptic active zone#GO:0048786;cell junction#GO:0030054;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015785.3|UniProtKB=G3RIA2 G3RIA2 LOC109023055 PTHR18843:SF2 TORSIN-1A-INTERACTING PROTEIN TORSIN-1A-INTERACTING PROTEIN 2 organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;endomembrane system organization#GO:0010256 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000015902.3|UniProtKB=G3RIK5 G3RIK5 C1H1orf185 PTHR37858:SF1 HYPOTHETICAL PROTEIN LOC689589 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 185 GORGO|Ensembl=ENSGGOG00000022996.2|UniProtKB=G3SJE6 G3SJE6 BRDT PTHR22880:SF175 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN TESTIS-SPECIFIC PROTEIN chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000015623.3|UniProtKB=A0A2I2Z7B5 A0A2I2Z7B5 NADK2 PTHR13158:SF5 FAMILY NOT NAMED NAD KINASE 2, MITOCHONDRIAL phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleotide metabolic process#GO:0006163;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000012684.3|UniProtKB=G3RAA8 G3RAA8 LOC101148900 PTHR44427:SF1 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM1 protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000016713.3|UniProtKB=A0A2I2Y337 A0A2I2Y337 ZNHIT1 PTHR13093:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1 ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 1 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000026152.2|UniProtKB=G3SCU0 G3SCU0 LRRTM3 PTHR24366:SF150 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 3 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000007361.3|UniProtKB=G3QWP1 G3QWP1 NR1I2 PTHR48092:SF8 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Angiogenesis#P00005>PAR#P00192 GORGO|Ensembl=ENSGGOG00000002110.2|UniProtKB=G3QI73 G3QI73 NACA2 PTHR21713:SF2 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA-2 establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000007687.3|UniProtKB=A0A2I2ZKC7 A0A2I2ZKC7 TMEM151B PTHR31893:SF4 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151B membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000043834.1|UniProtKB=A0A2I2ZU56 A0A2I2ZU56 LOC101130182 PTHR48553:SF1 SMALL PROLINE-RICH PROTEIN 2E SMALL PROLINE-RICH PROTEIN 2F GORGO|Ensembl=ENSGGOG00000005527.3|UniProtKB=G3QRZ5 G3QRZ5 KANSL1 PTHR22443:SF14 NON-SPECIFIC LETHAL 1, ISOFORM M KAT8 REGULATORY NSL COMPLEX SUBUNIT 1 protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545 GORGO|Ensembl=ENSGGOG00000015415.3|UniProtKB=G3RHB9 G3RHB9 LYZL4 PTHR11407:SF21 LYSOZYME C LYSOZYME-LIKE PROTEIN 4 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;lysozyme activity#GO:0003796;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;reproductive process#GO:0022414;single fertilization#GO:0007338;cellular process#GO:0009987;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342 organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;intracellular vesicle#GO:0097708;vesicle#GO:0031982;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;acrosomal vesicle#GO:0001669;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;cytoplasm#GO:0005737;secretory vesicle#GO:0099503 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000005894.3|UniProtKB=G3QSX1 G3QSX1 NTF3 PTHR11589:SF4 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIN-3 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 regulation of neuron apoptotic process#GO:0043523;neuron projection development#GO:0031175;negative regulation of neuron apoptotic process#GO:0043524;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular response to nerve growth factor stimulus#GO:1990090;cell projection morphogenesis#GO:0048858;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;cellular response to growth factor stimulus#GO:0071363;neuron development#GO:0048666;negative regulation of apoptotic process#GO:0043066;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731 presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell junction#GO:0030054;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 growth factor#PC00112;neurotrophic factor#PC00163 GORGO|Ensembl=ENSGGOG00000000913.3|UniProtKB=A0A2I2Z9W8 A0A2I2Z9W8 FOXP3 PTHR45796:SF5 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P3 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000023405.2|UniProtKB=G3RX31 G3RX31 MALT1 PTHR22576:SF40 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 regulation of signaling#GO:0023051;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;B cell activation#GO:0042113;immune response-activating signaling pathway#GO:0002757;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;signal transduction#GO:0007165;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851;defense response to other organism#GO:0098542;regulation of immune response#GO:0050776;cell activation#GO:0001775;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;positive regulation of signal transduction#GO:0009967;response to external biotic stimulus#GO:0043207;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;positive regulation of immune response#GO:0050778;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000016137.3|UniProtKB=A0A2I2ZP66 A0A2I2ZP66 RABGGTA PTHR11129:SF2 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA catalytic activity, acting on a protein#GO:0140096;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000042509.1|UniProtKB=A0A2I2Z1I9 A0A2I2Z1I9 ZNF81 PTHR24393:SF186 ZINC FINGER PROTEIN ENDOTHELIAL ZINC FINGER PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000038419.1|UniProtKB=G3QQE9 G3QQE9 LOC101136122 PTHR22950:SF185 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 2 glycine transmembrane transporter activity#GO:0015187;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;neutral L-amino acid transmembrane transporter activity#GO:0015175;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295 proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;alanine transport#GO:0032328;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;glycine transport#GO:0015816;carboxylic acid transmembrane transport#GO:1905039 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000014191.3|UniProtKB=G3RE67 G3RE67 AMBP PTHR46676:SF1 PROTEIN AMBP PROTEIN AMBP molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 GORGO|Ensembl=ENSGGOG00000010085.3|UniProtKB=A0A2I2YNE6 A0A2I2YNE6 CNBP PTHR23002:SF67 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN CCHC-TYPE ZINC FINGER NUCLEIC ACID BINDING PROTEIN single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000027388.2|UniProtKB=A0A2I2YMA2 A0A2I2YMA2 PTHR23105:SF142 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER RIBOSOMAL PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000025810.2|UniProtKB=A0A2I2Z9W3 A0A2I2Z9W3 LOC109024183 PTHR11831:SF54 30S 40S RIBOSOMAL PROTEIN SMALL RIBOSOMAL SUBUNIT PROTEIN US4 nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000011297.3|UniProtKB=G3R6Q5 G3R6Q5 GRK2 PTHR24355:SF22 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 2 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;G protein-coupled receptor binding#GO:0001664;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;signaling receptor binding#GO:0005102;protein serine/threonine kinase activity#GO:0004674 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of heart contraction#GO:0008016;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GPRK#P00840;Parkinson disease#P00049>GRK#P01234;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK2#P05943 GORGO|Ensembl=ENSGGOG00000016384.4|UniProtKB=G3RJU2 G3RJU2 ABI2 PTHR10460:SF26 ABL INTERACTOR FAMILY MEMBER ABL INTERACTOR 2 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell migration#GO:0016477;cellular process#GO:0009987 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;cell leading edge#GO:0031252;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013637.3|UniProtKB=G3S0E2 G3S0E2 ANO1 PTHR12308:SF13 ANOCTAMIN ANOCTAMIN-1 lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;intramembrane lipid carrier activity#GO:0140303;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;molecular carrier activity#GO:0140104;gated channel activity#GO:0022836;chloride channel activity#GO:0005254;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;monoatomic anion transport#GO:0006820;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;lipid transport#GO:0006869;monoatomic ion transmembrane transport#GO:0034220;phospholipid transport#GO:0015914;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;macromolecule localization#GO:0033036;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000008146.3|UniProtKB=G3QYM3 G3QYM3 TMEM187 PTHR15066:SF0 TRANSMEMBRANE PROTEIN 187 TRANSMEMBRANE PROTEIN 187 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;transport vesicle#GO:0030133;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000006649.3|UniProtKB=G3RR40 G3RR40 C8orf76 PTHR31919:SF1 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000011307.3|UniProtKB=G3R6Q9 G3R6Q9 PPP1R10 PTHR46557:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10 enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;protein phosphatase binding#GO:0019903;protein binding#GO:0005515 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000000887.3|UniProtKB=G3QF13 G3QF13 CLIP3 PTHR18916:SF77 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 3 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017 microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;nucleus#GO:0005634;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;microtubule end#GO:1990752 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000009772.3|UniProtKB=G3R2U0 G3R2U0 CDH8 PTHR24027:SF273 CADHERIN-23 CADHERIN-8 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cell migration#GO:0016477;cellular component assembly#GO:0022607;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;presynapse#GO:0098793;neuron projection#GO:0043005;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;adherens junction#GO:0005912;axon terminus#GO:0043679;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cell projection#GO:0042995;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;axon#GO:0030424;extracellular region#GO:0005576 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000027809.2|UniProtKB=G3SGJ8 G3SGJ8 BPIFA1 PTHR47015:SF1 BPI FOLD-CONTAINING FAMILY A MEMBER 1 BPI FOLD-CONTAINING FAMILY A MEMBER 1 chemical homeostasis#GO:0048878;multicellular organismal-level homeostasis#GO:0048871;homeostatic process#GO:0042592;multicellular organismal process#GO:0032501 GORGO|Ensembl=ENSGGOG00000006375.3|UniProtKB=G3QU46 G3QU46 SPNS3 PTHR23505:SF3 SPINSTER PROTEIN SPINSTER HOMOLOG 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000034913.2|UniProtKB=G3SKE0 G3SKE0 TMEM132B PTHR13388:SF12 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132B cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000003352.3|UniProtKB=G3S741 G3S741 ZNF808 PTHR24390:SF267 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 22 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013764.3|UniProtKB=G3RNP0 G3RNP0 RPP40 PTHR15396:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P40 RIBONUCLEASE P PROTEIN SUBUNIT P40 RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;ribonuclease P activity#GO:0004526 RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 protein-containing complex#GO:0032991;multimeric ribonuclease P complex#GO:0030681;ribonuclease MRP complex#GO:0000172;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular protein-containing complex#GO:0140535;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;endonuclease complex#GO:1905348;catalytic complex#GO:1902494 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012983.3|UniProtKB=G3RB48 G3RB48 LOC101147118 PTHR46708:SF3 TENASCIN TENASCIN-X extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000011253.3|UniProtKB=G3R6L0 G3R6L0 LOC101152062 PTHR11736:SF157 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B10 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025951.2|UniProtKB=G3RSV9 G3RSV9 PTHR12137:SF6 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 9 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000013021.4|UniProtKB=G3RB70 G3RB70 PRKCZ PTHR24351:SF241 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002679.3|UniProtKB=G3QJP0 G3QJP0 FOXK1 PTHR45881:SF4 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED FORKHEAD BOX PROTEIN K1 GORGO|Ensembl=ENSGGOG00000006024.3|UniProtKB=G3QT97 G3QT97 COL1A2 PTHR24023:SF568 COLLAGEN ALPHA COLLAGEN ALPHA-2(I) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 multicellular organismal process#GO:0032501;skin development#GO:0043588;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;skeletal system development#GO:0001501;system development#GO:0048731;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000040025.1|UniProtKB=A0A2I2YFW4 A0A2I2YFW4 PTHR11589:SF10 NERVE GROWTH FACTOR NGF -RELATED BETA-NERVE GROWTH FACTOR receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular response to growth factor stimulus#GO:0071363;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular response to nerve growth factor stimulus#GO:1990090;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;negative regulation of neuron apoptotic process#GO:0043524;regulation of neuron apoptotic process#GO:0043523;neuron projection development#GO:0031175;nervous system development#GO:0007399;regulation of trans-synaptic signaling#GO:0099177;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066 cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;extracellular region#GO:0005576;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708 growth factor#PC00112;neurotrophic factor#PC00163 GORGO|Ensembl=ENSGGOG00000000828.3|UniProtKB=G3QEW2 G3QEW2 PARP12 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000000894.3|UniProtKB=G3QF20 G3QF20 NAF1 PTHR31633:SF1 H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;protein-RNA complex organization#GO:0071826;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;ribonucleoprotein complex#GO:1990904 GORGO|Ensembl=ENSGGOG00000017147.3|UniProtKB=A0A2I2YWK7 A0A2I2YWK7 USB1 PTHR13522:SF3 U6 SNRNA PHOSPHODIESTERASE 1 U6 SNRNA PHOSPHODIESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000022185.2|UniProtKB=G3RV05 G3RV05 NOBOX PTHR47060:SF1 HOMEOBOX PROTEIN NOBOX HOMEOBOX PROTEIN NOBOX homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000005363.3|UniProtKB=G3QRJ9 G3QRJ9 ZCWPW1 PTHR15999:SF2 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006682.3|UniProtKB=A0A2I2Y3G4 A0A2I2Y3G4 PTHR22911:SF110 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G3-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023589.1|UniProtKB=G3SGQ7 G3SGQ7 ATP8 PTHR13722:SF0 ATP SYNTHASE PROTEIN 8 ATP SYNTHASE F(0) COMPLEX SUBUNIT 8 monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;oxidative phosphorylation#GO:0006119 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proton-transporting ATP synthase complex#GO:0045259;respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000000882.3|UniProtKB=G3QF11 G3QF11 PTHR24416:SF356 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;hemopoiesis#GO:0030097;developmental process#GO:0032502;cellular developmental process#GO:0048869;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cytokine-mediated signaling pathway#GO:0019221;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to chemical#GO:0042221;response to cytokine#GO:0034097;lymphocyte activation#GO:0046649;cell surface receptor signaling pathway#GO:0007166;B cell activation#GO:0042113;leukocyte differentiation#GO:0002521;positive regulation of cell population proliferation#GO:0008284;mononuclear cell differentiation#GO:1903131;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;immune system process#GO:0002376;response to peptide#GO:1901652 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000362.3|UniProtKB=G3QDN1 G3QDN1 GPHA2 PTHR31129:SF3 GLYCOPROTEIN HORMONE ALPHA-2 GLYCOPROTEIN HORMONE ALPHA-2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000014772.3|UniProtKB=A0A2I2YGZ4 A0A2I2YGZ4 SIGLEC10 PTHR12035:SF115 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 10 carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;organic acid binding#GO:0043177 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000014982.3|UniProtKB=G3RG76 G3RG76 CEP57L1 PTHR19336:SF10 UNCHARACTERIZED DUF1167 CENTROSOMAL PROTEIN CEP57L1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;organelle localization#GO:0051640;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;chromosome localization#GO:0050000;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;attachment of spindle microtubules to kinetochore#GO:0008608;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000001469.3|UniProtKB=G3QGJ4 G3QGJ4 RPF2 PTHR12728:SF0 BRIX DOMAIN CONTAINING PROTEIN RIBOSOME PRODUCTION FACTOR 2 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000014800.3|UniProtKB=G3RFS4 G3RFS4 POLR2A PTHR19376:SF37 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 DNA-templated transcription#GO:0006351;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription termination#GO:0006353;macromolecule metabolic process#GO:0043170;termination of RNA polymerase II transcription#GO:0006369;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000011572.3|UniProtKB=A0A2I2ZIP4 A0A2I2ZIP4 WNK3 PTHR13902:SF47 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;protein serine/threonine kinase activity#GO:0004674;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;transferase activity#GO:0016740;catalytic activity#GO:0003824;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 chemical homeostasis#GO:0048878;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762;homeostatic process#GO:0042592;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000036840.1|UniProtKB=A0A2I2Z9R3 A0A2I2Z9R3 MEIOSIN PTHR47658:SF1 HIGH MOBILITY GROUP B PROTEIN 12-RELATED MEIOSIS INITIATOR PROTEIN GORGO|Ensembl=ENSGGOG00000028603.2|UniProtKB=A0A2I2Z415 A0A2I2Z415 MIF4GD PTHR23254:SF17 EIF4G DOMAIN PROTEIN MIF4G DOMAIN-CONTAINING PROTEIN translation regulator activity#GO:0045182 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012660.4|UniProtKB=A0A2I2YWB4 A0A2I2YWB4 ADAP1 PTHR46021:SF5 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1 phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;phosphatidylinositol phosphate binding#GO:1901981;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid binding#GO:0008289 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000299.3|UniProtKB=G3QDH6 G3QDH6 KIAA0753 PTHR15732:SF4 PROTEIN MOONRAKER PROTEIN MOONRAKER macromolecule localization#GO:0033036;protein localization to cytoskeleton#GO:0044380;protein localization to microtubule cytoskeleton#GO:0072698;protein localization to microtubule organizing center#GO:1905508;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000008840.3|UniProtKB=G3R0F9 G3R0F9 CLEC12B PTHR47647:SF1 C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER B C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER B protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899 regulation of biological process#GO:0050789;signal transduction#GO:0007165;immune response-regulating signaling pathway#GO:0002764;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000043196.1|UniProtKB=A0A2I2Y9G0 A0A2I2Y9G0 PTHR19367:SF11 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-6 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000007535.3|UniProtKB=G3QX39 G3QX39 C18H16orf54 PTHR36134:SF1 TRANSMEMBRANE PROTEIN C16ORF54 TRANSMEMBRANE PROTEIN C16ORF54 GORGO|Ensembl=ENSGGOG00000025392.2|UniProtKB=G3RTC8 G3RTC8 TAB3 PTHR46253:SF3 TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 3 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000016002.3|UniProtKB=G3RIV7 G3RIV7 PBRM1 PTHR16062:SF19 SWI/SNF-RELATED PROTEIN POLYBROMO-1 chromatin binding#GO:0003682;binding#GO:0005488 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RSC-type complex#GO:0016586;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000026767.2|UniProtKB=A0A2I2Z4D3 A0A2I2Z4D3 PGK2 PTHR11406:SF10 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE 2 ribonucleotide binding#GO:0032553;kinase activity#GO:0016301;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;phosphoglycerate kinase activity#GO:0004618;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine ribonucleotide catabolic process#GO:0009154;hexose biosynthetic process#GO:0019319;nucleoside diphosphate catabolic process#GO:0009134;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;cytosol#GO:0005829 carbohydrate kinase#PC00065 GORGO|Ensembl=ENSGGOG00000013482.3|UniProtKB=A0A2I2YD02 A0A2I2YD02 SLC38A9 PTHR22950:SF244 AMINO ACID TRANSPORTER NEUTRAL AMINO ACID TRANSPORTER 9 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;amino acid transporter#PC00046 GORGO|Ensembl=ENSGGOG00000027194.2|UniProtKB=A0A2I2Y9C9 A0A2I2Y9C9 PTHR12642:SF5 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000013508.3|UniProtKB=G3RCE9 G3RCE9 CRYGS PTHR11818:SF6 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN S structural molecule activity#GO:0005198 sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000026034.2|UniProtKB=G3SBL9 G3SBL9 C8H10orf120 PTHR47509:SF1 MCG1612 SIMILAR TO HUMAN CHROMOSOME 10 OPEN READING FRAME 120 GORGO|Ensembl=ENSGGOG00000041708.1|UniProtKB=A0A2I2YHJ2 A0A2I2YHJ2 IL36RN PTHR10078:SF32 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-36 RECEPTOR ANTAGONIST PROTEIN signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;inflammatory response#GO:0006954;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;response to other organism#GO:0051707;immune response#GO:0006955;response to external stimulus#GO:0009605;defense response#GO:0006952;cellular response to molecule of bacterial origin#GO:0071219 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;interleukin superfamily#PC00128;cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000007067.3|UniProtKB=G3QVX5 G3QVX5 PSMB3 PTHR11599:SF185 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-3 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000039053.1|UniProtKB=A0A2I2ZP23 A0A2I2ZP23 KCNG3 PTHR11537:SF91 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNG3 transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;action potential#GO:0001508;metal ion transport#GO:0030001;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000000261.3|UniProtKB=G3QDE3 G3QDE3 KIFC1 PTHR47972:SF45 KINESIN-LIKE PROTEIN KLP-3 PROTEIN CLARET SEGREGATIONAL microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000010643.3|UniProtKB=G3R517 G3R517 C15H14orf39 PTHR35449:SF1 PROTEIN SIX6OS1 PROTEIN SIX6OS1 multicellular organismal reproductive process#GO:0048609;organelle fission#GO:0048285;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;homologous recombination#GO:0035825;reproductive process#GO:0022414;cellular response to stimulus#GO:0051716;germ cell development#GO:0007281;reciprocal homologous recombination#GO:0140527;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;cell cycle#GO:0007049;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;cellular developmental process#GO:0048869;meiotic nuclear division#GO:0140013;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;DNA damage response#GO:0006974;spermatogenesis#GO:0007283;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;male gamete generation#GO:0048232;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell cycle process#GO:0022402;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;double-strand break repair#GO:0006302;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;DNA metabolic process#GO:0006259;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;oogenesis#GO:0048477;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996 chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;central element#GO:0000801;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;synaptonemal structure#GO:0099086;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794 GORGO|Ensembl=ENSGGOG00000009723.3|UniProtKB=G3S016 G3S016 LOC101135984 PTHR46497:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000017090.3|UniProtKB=G3RLM5 G3RLM5 BICRAL PTHR15572:SF2 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN-LIKE regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000007412.3|UniProtKB=G3QWV6 G3QWV6 AKAP9 PTHR44981:SF1 PERICENTRIN-LIKE PROTEIN, ISOFORM F A-KINASE ANCHOR PROTEIN 9 protein kinase A binding#GO:0051018;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;protein kinase A regulatory subunit binding#GO:0034237;potassium channel regulator activity#GO:0015459;binding#GO:0005488;channel regulator activity#GO:0016247;protein binding#GO:0005515 microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;organelle localization#GO:0051640;centrosome localization#GO:0051642;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043 cell junction#GO:0030054;membraneless organelle#GO:0043228;cis-Golgi network#GO:0005801;centrosome#GO:0005813;microtubule organizing center#GO:0005815;Golgi apparatus#GO:0005794;cytoskeleton#GO:0005856;synaptic membrane#GO:0097060;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi stack#GO:0005795 GORGO|Ensembl=ENSGGOG00000007298.3|UniProtKB=G3QWI7 G3QWI7 KRT73 PTHR45616:SF31 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 73 structural molecule activity#GO:0005198 animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;epidermis development#GO:0008544;developmental process#GO:0032502;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;skin development#GO:0043588;organelle organization#GO:0006996;cellular process#GO:0009987;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043 intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001712.3|UniProtKB=G3QH67 G3QH67 ANLN PTHR21538:SF27 ANILLIN/RHOTEKIN RTKN ANILLIN mitotic cell cycle#GO:0000278;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;actomyosin structure organization#GO:0031032;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell division#GO:0051301;cell cycle process#GO:0022402;cortical actin cytoskeleton organization#GO:0030866;septin ring organization#GO:0031106;cytoskeleton-dependent cytokinesis#GO:0061640;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actomyosin contractile ring assembly#GO:0000915;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;septin cytoskeleton organization#GO:0032185 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cell periphery#GO:0071944;membraneless organelle#GO:0043228;contractile ring#GO:0070938;cytoskeleton#GO:0005856;actomyosin contractile ring#GO:0005826 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000010998.3|UniProtKB=G3R5Y3 G3R5Y3 ZNF513 PTHR24392:SF63 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 510 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014245.3|UniProtKB=G3RYF6 G3RYF6 ZNF354C PTHR23226:SF412 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000023542.2|UniProtKB=G3SES9 G3SES9 DRD4 PTHR24248:SF143 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE RECEPTOR D4A postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;adrenergic receptor signaling pathway#GO:0071875;negative regulation of cell communication#GO:0010648;G protein-coupled dopamine receptor signaling pathway#GO:0007212;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;negative regulation of cellular process#GO:0048523;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 GORGO|Ensembl=ENSGGOG00000009808.3|UniProtKB=G3R2W6 G3R2W6 SRSF6 PTHR23003:SF52 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE_ARGININE-RICH SPLICING FACTOR 6 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000041324.1|UniProtKB=G3QIB4 G3QIB4 LOC101145690 PTHR24377:SF708 IP01015P-RELATED ZINC FINGER PROTEIN 586 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014181.3|UniProtKB=G3RE56 G3RE56 CXXC5 PTHR13419:SF2 ZINC FINGER-CONTAINING CXXC-TYPE ZINC FINGER PROTEIN 5 nucleotide binding#GO:0000166;sequence-specific DNA binding#GO:0043565;heterocyclic compound binding#GO:1901363;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;nucleic acid binding#GO:0003676;binding#GO:0005488;small molecule binding#GO:0036094 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000026201.2|UniProtKB=A0A2I2ZFB2 A0A2I2ZFB2 PTHR16105:SF5 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING REGION-CONTAINING PROTEIN 3 pre-mRNA binding#GO:0036002;binding#GO:0005488;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000001306.4|UniProtKB=A0A2I2Y9M1 A0A2I2Y9M1 WIPI1 PTHR11227:SF23 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 1 small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981 process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;vacuole organization#GO:0007033;localization#GO:0051179;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;intracellular protein localization#GO:0008104;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036 phagophore assembly site#GO:0000407;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003536.3|UniProtKB=A0A2I2YFE7 A0A2I2YFE7 ADAM11 PTHR11905:SF114 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 11 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000015976.3|UniProtKB=G3RIS4 G3RIS4 MTMR8 PTHR10807:SF36 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR8 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856 organelle envelope#GO:0031967;membrane#GO:0016020;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000036262.1|UniProtKB=A0A2I2ZE69 A0A2I2ZE69 PTHR19269:SF73 TROPOMYOSIN TROPOMYOSIN 3, RELATED SEQUENCE 7 binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;muscle contraction#GO:0006936;actin filament-based process#GO:0030029 actin filament#GO:0005884;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000015267.3|UniProtKB=G3RGY7 G3RGY7 EEF2K PTHR45992:SF12 EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED EUKARYOTIC ELONGATION FACTOR 2 KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202 Oxidative stress response#P00046>eEF2K#P01127;p38 MAPK pathway#P05918>eEF2K#P06022 GORGO|Ensembl=ENSGGOG00000007621.3|UniProtKB=G3QXB3 G3QXB3 PTHR23266:SF240 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000015571.3|UniProtKB=G3RHR5 G3RHR5 LRRC47 PTHR10947:SF3 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000002992.3|UniProtKB=G3QKG8 G3QKG8 INSC PTHR21386:SF0 INSCUTEABLE PROTEIN INSCUTEABLE HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal adaptor activity#GO:0008093 regulation of cellular process#GO:0050794;localization#GO:0051179;intracellular protein localization#GO:0008104;biological regulation#GO:0065007;regulation of cell division#GO:0051302;macromolecule localization#GO:0033036;regulation of biological process#GO:0050789 cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000002605.3|UniProtKB=G3QJH2 G3QJH2 PREB PTHR23284:SF0 PROLACTIN REGULATORY ELEMENT BINDING PROTEIN GUANINE NUCLEOTIDE-EXCHANGE FACTOR SEC12 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;membrane organization#GO:0061024;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;COPII-coated vesicle budding#GO:0090114;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000012302.3|UniProtKB=G3R9C3 G3R9C3 GPR151 PTHR45695:SF1 LEUCOKININ RECEPTOR-RELATED G PROTEIN-COUPLED RECEPTOR 151 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000023922.2|UniProtKB=G3S1W9 G3S1W9 LOC101150653 PTHR26453:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6Y1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000022619.2|UniProtKB=G3SC46 G3SC46 CNR2 PTHR22750:SF10 G-PROTEIN COUPLED RECEPTOR CANNABINOID RECEPTOR 2 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000011850.3|UniProtKB=G3R854 G3R854 RTL9 PTHR47702:SF1 RETROTRANSPOSON GAG-LIKE PROTEIN 9 RETROTRANSPOSON GAG-LIKE PROTEIN 9 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000024946.2|UniProtKB=G3S049 G3S049 PTHR11655:SF29 60S/50S RIBOSOMAL PROTEIN L6/L9 LARGE RIBOSOMAL SUBUNIT PROTEIN UL6 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014408.3|UniProtKB=G3REQ8 G3REQ8 SMR3A PTHR14179:SF11 SMR1-RELATED SUBMAXILLARY GLAND ANDROGEN-REGULATED PROTEIN 3A endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 regulation of system process#GO:0044057;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000010130.3|UniProtKB=G3R3Q5 G3R3Q5 SPINDOC PTHR34589:SF1 SIMILAR TO RIKEN CDNA 2700081O15 SPINDLIN INTERACTOR AND REPRESSOR OF CHROMATIN-BINDING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000009189.3|UniProtKB=G3RV40 G3RV40 NKAIN1 PTHR13084:SF4 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 1 regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002578.3|UniProtKB=G3QJE7 G3QJE7 WSB2 PTHR15622:SF1 WD40 REPEAT PROTEIN WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 2 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000022278.2|UniProtKB=G3SIQ4 G3SIQ4 PTHR20515:SF17 BETA-DEFENSIN BETA-DEFENSIN 133 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;response to bacterium#GO:0009617;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;defense response to bacterium#GO:0042742;cell chemotaxis#GO:0060326;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;response to other organism#GO:0051707;response to external stimulus#GO:0009605;defense response#GO:0006952 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008028.3|UniProtKB=A0A2I2YIN5 A0A2I2YIN5 SLC45A4 PTHR19432:SF7 SUGAR TRANSPORTER POLYAMINE-TRANSPORTER SLC45A4 monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000010238.3|UniProtKB=G3R417 G3R417 COL28A1 PTHR24023:SF878 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXVIII) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000023375.2|UniProtKB=G3SJQ6 G3SJQ6 GATAD1 PTHR13340:SF2 GATA ZINC FINGER DOMAIN-CONTAINING GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000009019.3|UniProtKB=G3R0X2 G3R0X2 SDCBP PTHR12345:SF10 SYNTENIN RELATED SYNTENIN-1 protein binding#GO:0005515;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000038899.1|UniProtKB=A0A2I2ZEX1 A0A2I2ZEX1 SLC30A7 PTHR45755:SF6 FAMILY NOT NAMED ZINC TRANSPORTER 7 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592 Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;Golgi cis cisterna#GO:0000137;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;vesicle#GO:0031982;Golgi stack#GO:0005795;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000000465.4|UniProtKB=A0A2I2YNU2 A0A2I2YNU2 EXOC6B PTHR12702:SF3 SEC15 EXOCYST COMPLEX COMPONENT 6B cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234 cell periphery#GO:0071944;cell cortex#GO:0005938;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;exocyst#GO:0000145;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015899.3|UniProtKB=G3RIK7 G3RIK7 FAM81A PTHR22420:SF2 PROTEIN FAM81A PROTEIN FAM81A GORGO|Ensembl=ENSGGOG00000015538.3|UniProtKB=G3RHN4 G3RHN4 PTHR15375:SF22 ACTIVATOR OF S-PHASE KINASE-RELATED PROTEIN DBF4 HOMOLOG A molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of DNA replication#GO:0045740;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;positive regulation of DNA metabolic process#GO:0051054;regulation of cell cycle phase transition#GO:1901987;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 kinase activator#PC00138;kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000034939.2|UniProtKB=A0A2I2YIQ2 A0A2I2YIQ2 TCTN3 PTHR14611:SF4 TECTONIC FAMILY MEMBER TECTONIC-3 cell communication#GO:0007154;cilium organization#GO:0044782;smoothened signaling pathway#GO:0007224;organelle assembly#GO:0070925;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell projection organization#GO:0030030;signaling#GO:0023052;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cell surface receptor signaling pathway#GO:0007166;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;signal transduction#GO:0007165 GORGO|Ensembl=ENSGGOG00000042163.1|UniProtKB=A0A2I2YHE1 A0A2I2YHE1 UBE2I PTHR24067:SF280 UBIQUITIN-CONJUGATING ENZYME E2 SUMO-CONJUGATING ENZYME UBC9 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein sumoylation#GO:0016925 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000013849.3|UniProtKB=G3SEU1 G3SEU1 GSTP1 PTHR11571:SF141 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE P transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000026446.2|UniProtKB=G3RPK2 G3RPK2 EFCAB12 PTHR47225:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 12 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 12 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000025274.2|UniProtKB=G3RXU1 G3RXU1 TEFM PTHR21053:SF2 TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;mitochondrial nucleoid#GO:0042645;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoid#GO:0009295;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000016471.3|UniProtKB=G3S4E9 G3S4E9 MON1B PTHR13027:SF13 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG B GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;guanyl-nucleotide exchange factor complex#GO:0032045;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 GORGO|Ensembl=ENSGGOG00000036981.1|UniProtKB=A0A2I2Y965 A0A2I2Y965 HRCT1 PTHR23009:SF2 FAMILY NOT NAMED HISTIDINE-RICH CARBOXYL TERMINUS PROTEIN 1 GORGO|Ensembl=ENSGGOG00000001442.3|UniProtKB=G3QGH1 G3QGH1 DCHS2 PTHR24027:SF416 CADHERIN-23 CADHERIN DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell migration#GO:0016477;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000011934.3|UniProtKB=G3R8E1 G3R8E1 SLC6A4 PTHR11616:SF105 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT SEROTONIN TRANSPORTER ion binding#GO:0043167;small molecule binding#GO:0036094;cation binding#GO:0043169;solute:sodium symporter activity#GO:0015370;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;serotonin binding#GO:0051378;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;metal ion transmembrane transporter activity#GO:0046873;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075 sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;cellular localization#GO:0051641;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;organic hydroxy compound transport#GO:0015850;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization in cell#GO:0051649;monoatomic ion transmembrane transport#GO:0034220;neurotransmitter transport#GO:0006836;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;amino acid transport#GO:0006865;import into cell#GO:0098657;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054 primary active transporter#PC00068 5HT3 type receptor mediated signaling pathway#P04375>5HT transporter#P04421;5HT2 type receptor mediated signaling pathway#P04374>5HT transporter#P04417;5HT1 type receptor mediated signaling pathway#P04373>5HT transporter#P04409;5HT4 type receptor mediated signaling pathway#P04376>5HT transporter#P04431 GORGO|Ensembl=ENSGGOG00000024699.2|UniProtKB=G3S3Y1 G3S3Y1 WASL PTHR13037:SF23 FORMIN ACTIN NUCLEATION-PROMOTING FACTOR WASL protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;microtubule binding#GO:0008017 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 organelle membrane#GO:0031090;membraneless organelle#GO:0043228;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;endomembrane system#GO:0012505;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Huntington disease#P00029>N-Wasp#P00769;Cytoskeletal regulation by Rho GTPase#P00016>N-WASP#P00525 GORGO|Ensembl=ENSGGOG00000013729.2|UniProtKB=G3RCZ6 G3RCZ6 PTHR10533:SF15 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PANCREATIC POLYPEPTIDE binding#GO:0005488;signaling receptor binding#GO:0005102;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;neuropeptide hormone activity#GO:0005184 regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;feeding behavior#GO:0007631;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000006448.3|UniProtKB=G3QUA5 G3QUA5 TRAPPC1 PTHR23249:SF16 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000001638.3|UniProtKB=G3QGZ9 G3QGZ9 UBE3B PTHR45700:SF3 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3B catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 GORGO|Ensembl=ENSGGOG00000015139.3|UniProtKB=G3SE26 G3SE26 PTHR19981:SF34 TALIN TALIN-2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell adhesion#GO:0007155;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;cytoplasm#GO:0005737;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000027729.2|UniProtKB=G3S495 G3S495 POLR3A PTHR19376:SF72 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000041280.1|UniProtKB=A0A2I2YV90 A0A2I2YV90 SPATA33 PTHR38649:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 33 SPERMATOGENESIS-ASSOCIATED PROTEIN 33 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000034839.2|UniProtKB=A0A2I2Z2I7 A0A2I2Z2I7 BLZF1 PTHR13066:SF2 BASIC LEUCINE ZIPPER NUCLEAR FACTOR 1 BLZF1 PROTEIN GOLGIN-45 localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;Golgi organization#GO:0007030;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000006919.3|UniProtKB=G3QVJ6 G3QVJ6 LOC101141573 PTHR10722:SF22 60S RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN EL19 RNA binding#GO:0003723;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001627.3|UniProtKB=G3QGY8 G3QGY8 UGT2B10 PTHR48043:SF86 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2B10-RELATED catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;steroid metabolic process#GO:0008202 GORGO|Ensembl=ENSGGOG00000016440.4|UniProtKB=G3RJZ9 G3RJZ9 PTHR13742:SF36 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-ASSOCIATED PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;regulation of mitotic cell cycle#GO:0007346;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell cycle process#GO:0010564;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;neuron projection development#GO:0031175;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;neuron differentiation#GO:0030182;regulation of cell cycle#GO:0051726;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;neuron development#GO:0048666;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 chromatin#GO:0000785;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway feedback loops 2#P04398>Rb#P04654 GORGO|Ensembl=ENSGGOG00000013189.3|UniProtKB=G3RBL0 G3RBL0 SLC22A14 PTHR24064:SF48 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 14 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000006774.3|UniProtKB=G3QV66 G3QV66 PDE4B PTHR11347:SF108 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4B hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000000202.3|UniProtKB=G3QD89 G3QD89 GTSE1 PTHR21584:SF10 DIFFERENTIAL DISPLAY AND ACTIVATED BY P53 DDA3 /G2 S PHASE EXPRESSED 1 G2 AND S PHASE-EXPRESSED PROTEIN 1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 p53 pathway#P00059>B99#G04697;p53 pathway#P00059>B99#P04613 GORGO|Ensembl=ENSGGOG00000005468.3|UniProtKB=G3QRU1 G3QRU1 CD53 PTHR19282:SF39 TETRASPANIN LEUKOCYTE SURFACE ANTIGEN CD53 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002100.3|UniProtKB=G3QI66 G3QI66 CHRNG PTHR18945:SF60 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT GAMMA monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to chemical#GO:0042221;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;muscle system process#GO:0003012;response to stimulus#GO:0050896;signaling#GO:0023052;skeletal muscle contraction#GO:0003009;cellular response to chemical stimulus#GO:0070887;nervous system process#GO:0050877;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;acetylcholine receptor signaling pathway#GO:0095500;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;transport#GO:0006810;muscle contraction#GO:0006936;establishment of localization#GO:0051234;system process#GO:0003008;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;trans-synaptic signaling#GO:0099537;neuromuscular process#GO:0050905;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;cell junction#GO:0030054;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>gamma#P01094 GORGO|Ensembl=ENSGGOG00000024127.2|UniProtKB=G3RVY6 G3RVY6 GTF2A2 PTHR10966:SF5 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515 gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390;General transcription regulation#P00023>TFIIA complex#P00662 GORGO|Ensembl=ENSGGOG00000004906.3|UniProtKB=G3S7G1 G3S7G1 LAMA2 PTHR10574:SF291 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 tissue development#GO:0009888;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000002609.3|UniProtKB=G3QJH3 G3QJH3 GNB3 PTHR19850:SF31 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-3 signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095;heterotrimeric G-protein#PC00117;G-protein#PC00020 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Enkephalin release#P05913>G-Protein (i)#P05974;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;GABA-B receptor II signaling#P05731>Gbeta#P05755;Enkephalin release#P05913>G-Protein (s)#P05977;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;PI3 kinase pathway#P00048>Gbetagamma#P01188;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Wnt signaling pathway#P00057>GBeta#P01457;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743 GORGO|Ensembl=ENSGGOG00000016249.4|UniProtKB=G3RJG1 G3RJG1 IGFBP7 PTHR14186:SF19 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;tube development#GO:0035295;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000005651.3|UniProtKB=G3QSA3 G3QSA3 ZNF136 PTHR24379:SF22 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 441 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013449.3|UniProtKB=G3RC94 G3RC94 GRWD1 PTHR45903:SF1 GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1 GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000006979.3|UniProtKB=G3QVQ0 G3QVQ0 ALAD PTHR11458:SF0 DELTA-AMINOLEVULINIC ACID DEHYDRATASE DELTA-AMINOLEVULINIC ACID DEHYDRATASE hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;porphyrin-containing compound biosynthetic process#GO:0006779;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 dehydratase#PC00091 Heme biosynthesis#P02746>porphobilinogen synthase#P02979 GORGO|Ensembl=ENSGGOG00000006824.3|UniProtKB=G3QVB4 G3QVB4 TPK1 PTHR13622:SF14 THIAMIN PYROPHOSPHOKINASE THIAMINE PYROPHOSPHOKINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transferase#PC00220;kinase#PC00137 Thiamin metabolism#P02780>Thiamine kinase#P03176 GORGO|Ensembl=ENSGGOG00000042631.1|UniProtKB=A0A2I2ZLK8 A0A2I2ZLK8 PTHR23266:SF345 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 6 antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000009364.3|UniProtKB=G3R1R9 G3R1R9 RPL3L PTHR11363:SF7 60S RIBOSOMAL PROTEIN L3-RELATED RIBOSOMAL PROTEIN UL3-LIKE binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003381.3|UniProtKB=G3QLG9 G3QLG9 IFITM1 PTHR13999:SF6 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 1 response to peptide#GO:1901652;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cell surface receptor signaling pathway#GO:0007166;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;response to type II interferon#GO:0034341;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;response to virus#GO:0009615;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000025694.2|UniProtKB=G3RV37 G3RV37 OOSP2 PTHR14380:SF7 PLACENTA-SPECIFIC PROTEIN 1 OOCYTE-SECRETED PROTEIN 2 GORGO|Ensembl=ENSGGOG00000007487.3|UniProtKB=G3S130 G3S130 IQSEC3 PTHR10663:SF318 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 3 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;biological regulation#GO:0065007;regulation of endocytosis#GO:0030100;regulation of biological quality#GO:0065008;regulation of transport#GO:0051049;regulation of localization#GO:0032879 postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000015193.3|UniProtKB=G3RGS0 G3RGS0 CRIP3 PTHR24215:SF31 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE-RICH PROTEIN 1 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000001735.3|UniProtKB=A0A2I2Z6L1 A0A2I2Z6L1 BLVRA PTHR43377:SF13 BILIVERDIN REDUCTASE A BILIVERDIN REDUCTASE A catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000016819.3|UniProtKB=G3RKY1 G3RKY1 DHX15 PTHR18934:SF95 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX15 binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007597.3|UniProtKB=G3QXA1 G3QXA1 JAG2 PTHR24044:SF421 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Next#P01103;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Serrate#P01104 GORGO|Ensembl=ENSGGOG00000001626.3|UniProtKB=G3QGY6 G3QGY6 ATP5MC1 PTHR10031:SF59 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C3, MITOCHONDRIAL ATP synthase#PC00002;transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000015582.3|UniProtKB=A0A2I2YJE5 A0A2I2YJE5 KCND3 PTHR11537:SF182 VOLTAGE-GATED POTASSIUM CHANNEL A-TYPE VOLTAGE-GATED POTASSIUM CHANNEL KCND3 voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 metal ion transport#GO:0030001;export from cell#GO:0140352;action potential#GO:0001508;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;voltage-gated potassium channel complex#GO:0008076;cell junction#GO:0030054;transporter complex#GO:1990351;cell body#GO:0044297;plasma membrane protein complex#GO:0098797;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell projection#GO:0042995;neuronal cell body#GO:0043025;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic tree#GO:0097447;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000040579.1|UniProtKB=A0A2I2YR80 A0A2I2YR80 HYCC1 PTHR31220:SF4 HYCCIN RELATED HYCCIN phosphatidylinositol phosphate biosynthetic process#GO:0046854;localization within membrane#GO:0051668;localization#GO:0051179;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;protein localization to plasma membrane#GO:0072659;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;intracellular protein localization#GO:0008104;organophosphate metabolic process#GO:0019637;macromolecule localization#GO:0033036;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000016723.3|UniProtKB=A0A2I2ZUV9 A0A2I2ZUV9 CFAP119 PTHR28457:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 119 GORGO|Ensembl=ENSGGOG00000008472.3|UniProtKB=A0A2I2Z6B5 A0A2I2Z6B5 SH2B1 PTHR10872:SF3 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 1 receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;signaling adaptor activity#GO:0035591 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000041897.1|UniProtKB=A0A2I2YXG3 A0A2I2YXG3 GATD3 PTHR10224:SF9 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL GORGO|Ensembl=ENSGGOG00000026362.2|UniProtKB=A0A2I2ZQP9 A0A2I2ZQP9 LOC101125574 PTHR43880:SF34 ALCOHOL DEHYDROGENASE S-(HYDROXYMETHYL)GLUTATHIONE DEHYDROGENASE metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;ion binding#GO:0043167;transition metal ion binding#GO:0046914;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;zinc ion binding#GO:0008270 metabolic process#GO:0008152;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;detoxification#GO:0098754;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;response to toxic substance#GO:0009636;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;small molecule catabolic process#GO:0044282;cellular detoxification of aldehyde#GO:0110095;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000001141.3|UniProtKB=G3QFP7 G3QFP7 SEC23A PTHR11141:SF7 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23A enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179 vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000016155.3|UniProtKB=Q3BCR3 Q3BCR3 TPMT PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000002437.3|UniProtKB=G3SJC4 G3SJC4 LSP1 PTHR18949:SF1 CALDESMON LYMPHOCYTE-SPECIFIC PROTEIN 1 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000027129.2|UniProtKB=G3SEM8 G3SEM8 DIS3L2 PTHR23355:SF68 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000003283.3|UniProtKB=G3S5C2 G3S5C2 KAT5 PTHR10615:SF219 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT5 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402 double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137;Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093 GORGO|Ensembl=ENSGGOG00000036661.1|UniProtKB=A0A2I2ZAU5 A0A2I2ZAU5 CTXN3 PTHR16736:SF1 CORTEXIN-1-RELATED CORTEXIN-3 GORGO|Ensembl=ENSGGOG00000008439.3|UniProtKB=G3QZE2 G3QZE2 HMG20A PTHR46040:SF1 HIGH MOBILITY GROUP PROTEIN 2 HIGH MOBILITY GROUP PROTEIN 20A regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000034965.2|UniProtKB=G3SKK9 G3SKK9 FAM78B PTHR31655:SF0 PROTEIN FAM78A PROTEIN FAM78B GORGO|Ensembl=ENSGGOG00000036580.1|UniProtKB=A0A2I2ZJ42 A0A2I2ZJ42 PTHR23236:SF42 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4B nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000004226.3|UniProtKB=G3RVY0 G3RVY0 AIMP1 PTHR11586:SF51 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;enzyme activator activity#GO:0008047 tRNA metabolic process#GO:0006399;leukocyte migration#GO:0050900;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;cell migration#GO:0016477;amino acid metabolic process#GO:0006520;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cell-cell signaling#GO:0007267;biosynthetic process#GO:0009058;immune system process#GO:0002376;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;cell communication#GO:0007154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;protein biosynthetic process#GO:0160307;cell motility#GO:0048870;signaling#GO:0023052 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extracellular region#GO:0005576 translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000016178.3|UniProtKB=G3RJA0 G3RJA0 ADAT2 PTHR11079:SF208 CYTOSINE DEAMINASE FAMILY MEMBER TRNA-SPECIFIC ADENOSINE-34 DEAMINASE CATALYTIC SUBUNIT ADAT2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;tRNA-specific adenosine deaminase activity#GO:0008251;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;adenosine to inosine editing#GO:0006382;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;base conversion or substitution editing#GO:0016553;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCTP deaminase#P02920;Salvage pyrimidine ribonucleotides#P02775>Cytosine deaminase#P03155;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154 GORGO|Ensembl=ENSGGOG00000001318.3|UniProtKB=G3SI93 G3SI93 PRAG1 PTHR22972:SF3 SERINE/THREONINE PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE PRAG1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of cellular process#GO:0050794;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of biological process#GO:0050789 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007661.3|UniProtKB=A0A2I2Y7N2 A0A2I2Y7N2 ALDH1A2 PTHR11699:SF102 ALDEHYDE DEHYDROGENASE-RELATED RETINAL DEHYDROGENASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 biosynthetic process#GO:0009058;biological regulation#GO:0065007;aldehyde catabolic process#GO:0046185;hormone metabolic process#GO:0042445;terpenoid biosynthetic process#GO:0016114;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;monocarboxylic acid biosynthetic process#GO:0072330;diterpenoid biosynthetic process#GO:0016102;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid biosynthetic process#GO:0046394;regulation of hormone levels#GO:0010817;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;isoprenoid biosynthetic process#GO:0008299;oxoacid metabolic process#GO:0043436 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000000689.3|UniProtKB=G3R228 G3R228 ZKSCAN3 PTHR23226:SF130 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004895.3|UniProtKB=G3QQD2 G3QQD2 GARIN1B PTHR22574:SF13 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 1B GORGO|Ensembl=ENSGGOG00000026123.2|UniProtKB=G3RYG3 G3RYG3 LIN7C PTHR14063:SF5 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological quality#GO:0065008;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of synapse organization#GO:0050807;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;secretion#GO:0046903;regulation of synapse structure or activity#GO:0050803;cell communication#GO:0007154;localization#GO:0051179;regulation of cell junction assembly#GO:1901888;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;signal release#GO:0023061;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of growth#GO:0040008;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;establishment of localization#GO:0051234;transport#GO:0006810;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of synapse assembly#GO:0051963;vesicle localization#GO:0051648 adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991 cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000000454.3|UniProtKB=G3S9W3 G3S9W3 PGM3 PTHR45955:SF5 PHOSPHOACETYLGLUCOSAMINE MUTASE PHOSPHOACETYLGLUCOSAMINE MUTASE intramolecular phosphotransferase activity#GO:0016868;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 UDP-N-acetylglucosamine biosynthetic process#GO:0006048;anatomical structure development#GO:0048856;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;cell development#GO:0048468;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;developmental process#GO:0032502;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;cellular developmental process#GO:0048869;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;hemopoiesis#GO:0030097;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225 mutase#PC00160;isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000007551.3|UniProtKB=A0A2I2YER8 A0A2I2YER8 HIF3A PTHR23043:SF18 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA HYPOXIA-INDUCIBLE FACTOR 3-ALPHA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;intracellular chemical homeostasis#GO:0055082;response to hypoxia#GO:0001666;cellular homeostasis#GO:0019725;regulation of gene expression#GO:0010468;chemical homeostasis#GO:0048878;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;response to abiotic stimulus#GO:0009628;cellular response to hypoxia#GO:0071456;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000011463.3|UniProtKB=G3R765 G3R765 CHD1 PTHR45623:SF7 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD1 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ATP hydrolysis activity#GO:0016887;DNA binding#GO:0003677;hydrolase activity#GO:0016787 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000039181.1|UniProtKB=A0A2I2YJM7 A0A2I2YJM7 PTHR15606:SF8 DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED J DOMAIN-CONTAINING PROTEIN nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000010306.3|UniProtKB=G3R463 G3R463 ZBTB33 PTHR24399:SF24 ZINC FINGER AND BTB DOMAIN-CONTAINING TRANSCRIPTIONAL REGULATOR KAISO sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024408.2|UniProtKB=A0A2I2YMH1 A0A2I2YMH1 PTHR43899:SF20 RH59310P 17BETA-ESTRADIOL 17-DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006439.3|UniProtKB=G3QUA0 G3QUA0 NUP85 PTHR13373:SF21 FROUNT PROTEIN-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP85 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 gene expression#GO:0010467;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;protein transport#GO:0015031;protein import into nucleus#GO:0006606;biosynthetic process#GO:0009058;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;macromolecule biosynthetic process#GO:0009059;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000011135.3|UniProtKB=G3R6B1 G3R6B1 HLCS PTHR12835:SF5 BIOTIN PROTEIN LIGASE BIOTIN--PROTEIN LIGASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000009021.3|UniProtKB=G3R0W8 G3R0W8 NLRP10 PTHR45690:SF4 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 10 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000002662.3|UniProtKB=G3SIM1 G3SIM1 PTHR17388:SF2 SECRETOGRANIN III SECRETOGRANIN-3 localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036 cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000038240.1|UniProtKB=A0A2I2YFC9 A0A2I2YFC9 PTHR11581:SF15 30S/40S RIBOSOMAL PROTEIN S4 40S RIBOSOMAL PROTEIN S4 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010201.3|UniProtKB=G3R3X6 G3R3X6 SEL1L2 PTHR11102:SF53 SEL-1-LIKE PROTEIN PROTEIN SEL-1 HOMOLOG 2 protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 GORGO|Ensembl=ENSGGOG00000007071.3|UniProtKB=G3QVX8 G3QVX8 NPM2 PTHR22747:SF14 NUCLEOPLASMIN NUCLEOPLASMIN-2 binding#GO:0005488;nucleic acid binding#GO:0003676;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515;RNA binding#GO:0003723 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000039135.1|UniProtKB=A0A2I2ZSB8 A0A2I2ZSB8 PTHR11441:SF0 THYMIDINE KINASE THYMIDINE KINASE, CYTOSOLIC transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;deoxynucleoside kinase activity#GO:0019136 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleoside monophosphate biosynthetic process#GO:0009124 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine deoxyribonucleotides#P02774>Deoxyuridine kinase#P03146;Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine kinase#P03147 GORGO|Ensembl=ENSGGOG00000015844.3|UniProtKB=G3RIE9 G3RIE9 GLYCTK PTHR12227:SF0 GLYCERATE KINASE GLYCERATE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 carbohydrate kinase#PC00065 GORGO|Ensembl=ENSGGOG00000013520.3|UniProtKB=G3RCF6 G3RCF6 SLC10A3 PTHR10361:SF3 SODIUM-BILE ACID COTRANSPORTER P3 PROTEIN symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;bile acid transmembrane transporter activity#GO:0015125;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 lipid transport#GO:0006869;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;establishment of localization#GO:0051234;bile acid and bile salt transport#GO:0015721;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;lipid localization#GO:0010876 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000011974.3|UniProtKB=G3R8I0 G3R8I0 MORC3 PTHR23336:SF17 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 3 chromatin-protein adaptor activity#GO:0140463;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;antiviral innate immune response#GO:0140374;response to virus#GO:0009615;immune system process#GO:0002376 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000012386.3|UniProtKB=A0A2I2ZMF3 A0A2I2ZMF3 PIK3CD PTHR10048:SF35 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742 intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;phosphatidylinositol phosphate biosynthetic process#GO:0046854;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;cell motility#GO:0048870;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;intracellular signaling cassette#GO:0141124;biosynthetic process#GO:0009058;biological regulation#GO:0065007;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;organophosphate metabolic process#GO:0019637 intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 kinase#PC00137 Integrin signalling pathway#P00034>PI3K#P00936;Axon guidance mediated by netrin#P00009>PI3K#P00363;p53 pathway feedback loops 2#P04398>PI3K#P04661;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;PDGF signaling pathway#P00047>PI3K#P01168;Ras Pathway#P04393>PI3K#P04567;Apoptosis signaling pathway#P00006>PI3K#P00310;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;VEGF signaling pathway#P00056>PI3K#P01413;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;T cell activation#P00053>PI3K#P01322;FGF signaling pathway#P00021>PI3K#P00640;B cell activation#P00010>PI3K#P00391;EGF receptor signaling pathway#P00018>PI3K#P00557;Angiogenesis#P00005>PI3K#P00236 GORGO|Ensembl=ENSGGOG00000004463.3|UniProtKB=G3SG77 G3SG77 TAF7L PTHR12228:SF8 TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 7-LIKE nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000005545.3|UniProtKB=G3QS12 G3QS12 ASNA1 PTHR10803:SF3 ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE ATPASE GET3 ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365 endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023436.2|UniProtKB=G3S2Y8 G3S2Y8 TLCD4 PTHR13439:SF1 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 4 chemical homeostasis#GO:0048878;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012532.3|UniProtKB=G3R9X4 G3R9X4 CACTIN PTHR21737:SF6 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 SPLICING FACTOR CACTIN RNA biosynthetic process#GO:0032774;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;biosynthetic process#GO:0009058;negative regulation of response to stimulus#GO:0048585;macromolecule biosynthetic process#GO:0009059;regulation of innate immune response#GO:0045088;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;negative regulation of response to external stimulus#GO:0032102;RNA processing#GO:0006396;negative regulation of innate immune response#GO:0045824;regulation of response to external stimulus#GO:0032101;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002405.3|UniProtKB=G3QIZ2 G3QIZ2 ETV3L PTHR11849:SF306 ETS ETS TRANSLOCATION VARIANT 3-LIKE PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000025142.2|UniProtKB=G3SF03 G3SF03 CLTRN PTHR46884:SF1 COLLECTRIN COLLECTRIN EGF receptor signaling pathway#P00018>Ras#P00552 GORGO|Ensembl=ENSGGOG00000026437.2|UniProtKB=G3RVZ6 G3RVZ6 LOC101150390 PTHR48018:SF166 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016317.3|UniProtKB=G3S7K8 G3S7K8 ADGRL2 PTHR23192:SF70 OLFACTOMEDIN-RELATED ADHESION G PROTEIN-COUPLED RECEPTOR L2 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000014628.3|UniProtKB=G3RFA6 G3RFA6 LOC109023480 PTHR11994:SF47 60S RIBOSOMAL PROTEIN L11-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL5 nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000024649.2|UniProtKB=G3RYI7 G3RYI7 PTHR35345:SF1 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 2 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 2 organelle fission#GO:0048285;localization#GO:0051179;nuclear division#GO:0000280;organelle localization#GO:0051640;telomere tethering at nuclear periphery#GO:0034398;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cellular component organization#GO:0016043;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;telomere localization#GO:0034397;cell cycle#GO:0007049;cell cycle process#GO:0022402;meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome segregation#GO:0007059;homologous chromosome pairing at meiosis#GO:0007129;chromosome localization#GO:0050000;organelle organization#GO:0006996;cellular process#GO:0009987 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane#GO:0016020;nucleus#GO:0005634;organelle inner membrane#GO:0019866;nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016357.3|UniProtKB=G3RJR3 G3RJR3 CD37 PTHR19282:SF263 TETRASPANIN LEUKOCYTE ANTIGEN CD37 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000041596.1|UniProtKB=A0A2I2Z3V6 A0A2I2Z3V6 CHURC1 PTHR31931:SF2 PROTEIN CHURCHILL PROTEIN CHURCHILL cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to fibroblast growth factor#GO:0071774;cell surface receptor signaling pathway#GO:0007166;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344 GORGO|Ensembl=ENSGGOG00000023297.2|UniProtKB=A0A2I2ZQH5 A0A2I2ZQH5 PTHR11071:SF490 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000013144.3|UniProtKB=G3RBG7 G3RBG7 GET1 PTHR42650:SF1 TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 GORGO|Gene=FPR1|UniProtKB=P79176 P79176 FPR1 PTHR24225:SF15 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 1 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;immune response-activating signaling pathway#GO:0002757;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;regulation of biological quality#GO:0065008;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000014343.3|UniProtKB=G3REJ9 G3REJ9 LRRC24 PTHR24366:SF129 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 24 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000013586.3|UniProtKB=G3QJN1 G3QJN1 LOC101147313 PTHR11632:SF51 SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;anaerobic respiration#GO:0009061 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;cell periphery#GO:0071944;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000038003.1|UniProtKB=A0A2I2Z344 A0A2I2Z344 MRPL17 PTHR14413:SF24 RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012669.3|UniProtKB=A0A2I2Y409 A0A2I2Y409 TNNT2 PTHR11521:SF5 TROPONIN T TROPONIN T, CARDIAC MUSCLE cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;heart process#GO:0003015;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;system process#GO:0003008;heart contraction#GO:0060047;cellular developmental process#GO:0048869;muscle contraction#GO:0006936;developmental process#GO:0032502;striated muscle contraction#GO:0006941;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system process#GO:0003013 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000005630.3|UniProtKB=G3RTJ5 G3RTJ5 LSM14B PTHR13586:SF1 SCD6 PROTEIN-RELATED PROTEIN LSM14 HOMOLOG B binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;P-body assembly#GO:0033962 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003805.3|UniProtKB=G3QMK1 G3QMK1 RFX3 PTHR12619:SF20 RFX TRANSCRIPTION FACTOR FAMILY TRANSCRIPTION FACTOR RFX3 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000003800.3|UniProtKB=G3RQ21 G3RQ21 GPR37L1 PTHR46216:SF4 PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER G PROTEIN-COUPLED RECEPTOR 37-LIKE 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;G protein-coupled receptor signaling pathway#GO:0007186;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Parkinson disease#P00049>Pael-R#P01229 GORGO|Ensembl=ENSGGOG00000010530.3|UniProtKB=A0A2I2YIR3 A0A2I2YIR3 CD99 PTHR15076:SF15 CD99/MIC2 PROTEIN RELATED CD99 ANTIGEN positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;homotypic cell-cell adhesion#GO:0034109;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cell migration#GO:0016477;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;lymphocyte migration#GO:0072676;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;regulation of cell motility#GO:2000145;cell adhesion#GO:0007155;mononuclear cell migration#GO:0071674;immune system process#GO:0002376;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cell motility#GO:0048870;regulation of leukocyte migration#GO:0002685;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000010700.3|UniProtKB=G3R578 G3R578 ALPL PTHR11596:SF74 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 animal organ development#GO:0048513;anatomical structure development#GO:0048856;bone mineralization#GO:0030282;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;biomineral tissue development#GO:0031214;multicellular organismal process#GO:0032501;ossification#GO:0001503;tissue development#GO:0009888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000015106.4|UniProtKB=G3RGJ5 G3RGJ5 POC5 PTHR28618:SF1 CENTROSOMAL PROTEIN POC5 CENTROSOMAL PROTEIN POC5 GORGO|Ensembl=ENSGGOG00000002989.3|UniProtKB=G3QKG6 G3QKG6 MAU2 PTHR21394:SF0 MAU2 CHROMATID COHESION FACTOR HOMOLOG MAU2 CHROMATID COHESION FACTOR HOMOLOG catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitotic sister chromatid cohesion#GO:0007064;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000036429.1|UniProtKB=A0A2I2YFI0 A0A2I2YFI0 SOCS3 PTHR10155:SF11 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 3 signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;protein binding#GO:0005515 signaling#GO:0023052;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;response to peptide#GO:1901652;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of signaling#GO:0023051;cytokine-mediated signaling pathway#GO:0019221;negative regulation of signaling#GO:0023057;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;response to cytokine#GO:0034097;response to chemical#GO:0042221;negative regulation of response to stimulus#GO:0048585;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 GORGO|Ensembl=ENSGGOG00000023192.2|UniProtKB=G3SFM8 G3SFM8 HSF2 PTHR10015:SF185 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000016100.3|UniProtKB=A0A2I2Y8B9 A0A2I2Y8B9 MDP1 PTHR17901:SF14 MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1 MAGNESIUM-DEPENDENT PHOSPHATASE 1 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000009792.3|UniProtKB=A0A2I2ZEK8 A0A2I2ZEK8 PPIL2 PTHR45625:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;cis-trans isomerase activity#GO:0016859;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000003000.3|UniProtKB=A0A2I2YCR6 A0A2I2YCR6 PEX5L PTHR10130:SF1 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEX5-RELATED PROTEIN signal sequence receptor activity#GO:0005048;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;peroxisomal transport#GO:0043574;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;peroxisome organization#GO:0007031;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;cytosol#GO:0005829;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000016794.3|UniProtKB=G3RKV3 G3RKV3 CNDP2 PTHR43270:SF11 BETA-ALA-HIS DIPEPTIDASE CYTOSOLIC NON-SPECIFIC DIPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000007133.3|UniProtKB=G3RMH2 G3RMH2 UAP1L1 PTHR11952:SF6 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE-LIKE PROTEIN 1 nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleoside phosphate metabolic process#GO:0006753;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000010219.3|UniProtKB=A0A2I2ZGA9 A0A2I2ZGA9 CADM1 PTHR45889:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cell adhesion#GO:0007155;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;positive regulation of response to external stimulus#GO:0032103;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte mediated immunity#GO:0002703;regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;regulation of immune response#GO:0050776;cell recognition#GO:0008037;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;detection of stimulus#GO:0051606;homophilic cell-cell adhesion#GO:0007156;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stress#GO:0080134 cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000039166.1|UniProtKB=A0A2I2Z0C1 A0A2I2Z0C1 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002453.3|UniProtKB=G3QJ33 G3QJ33 CDC40 PTHR43979:SF1 PRE-MRNA-PROCESSING FACTOR 17 PRE-MRNA-PROCESSING FACTOR 17 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000003961.3|UniProtKB=G3QMZ2 G3QMZ2 PHEX PTHR11733:SF133 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000014215.3|UniProtKB=G3RE93 G3RE93 ADGRG5 PTHR12011:SF326 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G5 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015146.3|UniProtKB=G3RGM7 G3RGM7 WDCP PTHR14897:SF5 WD REPEAT AND COILED-COIL-CONTAINING PROTEIN WD REPEAT AND COILED-COIL-CONTAINING PROTEIN protein binding#GO:0005515;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488 GORGO|Ensembl=ENSGGOG00000008920.3|UniProtKB=G3R0M8 G3R0M8 TIGD6 PTHR19303:SF52 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 6 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000006783.4|UniProtKB=G3QV78 G3QV78 PDE1C PTHR11347:SF32 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1C hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;cell body#GO:0044297 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000000172.3|UniProtKB=G3QD60 G3QD60 NUPR1 PTHR17149:SF5 NUCLEAR PROTEIN 1 AND 2 NUCLEAR PROTEIN 1 regulation of cell population proliferation#GO:0042127;negative regulation of cell cycle#GO:0045786;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;negative regulation of cell population proliferation#GO:0008285;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000024558.2|UniProtKB=G3SI46 G3SI46 RPAP3 PTHR46423:SF1 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 GORGO|Ensembl=ENSGGOG00000026524.2|UniProtKB=G3SEV4 G3SEV4 PTHR46349:SF2 CINGULIN-LIKE PROTEIN 1-RELATED CINGULIN-LIKE PROTEIN 1 localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cell junction#GO:1902414;macromolecule localization#GO:0033036 apical junction complex#GO:0043296;cell-cell junction#GO:0005911;bicellular tight junction#GO:0005923;cell junction#GO:0030054;tight junction#GO:0070160;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 GORGO|Ensembl=ENSGGOG00000021937.2|UniProtKB=G3S7I4 G3S7I4 RRAGA PTHR11259:SF7 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN A ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;negative regulation of catabolic process#GO:0009895;positive regulation of TOR signaling#GO:0032008;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;lysosome#GO:0005764;nucleus#GO:0005634;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000022801.2|UniProtKB=G3SGB7 G3SGB7 LOC101128093 PTHR12146:SF10 40S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN ES10 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011454.3|UniProtKB=G3R740 G3R740 MAF PTHR10129:SF9 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAF sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;animal organ development#GO:0048513;lens development in camera-type eye#GO:0002088;cellular process#GO:0009987;sensory system development#GO:0048880;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;camera-type eye development#GO:0043010;visual system development#GO:0150063;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008183.3|UniProtKB=G3QYQ7 G3QYQ7 MTARC2 PTHR14237:SF27 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 2 transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;nitrate metabolic process#GO:0042126;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000001336.3|UniProtKB=G3RL47 G3RL47 TMEM170A PTHR22779:SF2 SD17342P TRANSMEMBRANE PROTEIN 170A cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786;endomembrane system organization#GO:0010256 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 GORGO|Ensembl=ENSGGOG00000027997.2|UniProtKB=G3S4W1 G3S4W1 PTHR11461:SF27 SERINE PROTEASE INHIBITOR, SERPIN SERPIN H1 endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000005529.3|UniProtKB=G3SDX2 G3SDX2 BAG6 PTHR15204:SF0 LARGE PROLINE-RICH PROTEIN BAG6 LARGE PROLINE-RICH PROTEIN BAG6 protein binding#GO:0005515;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488 cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000002421.3|UniProtKB=G3QJ07 G3QJ07 C7H8orf58 PTHR37336:SF1 SIMILAR TO 9930012K11RIK PROTEIN SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 58 GORGO|Ensembl=ENSGGOG00000007232.3|UniProtKB=G3QWC0 G3QWC0 SUPT4H1 PTHR12882:SF1 SUPPRESSOR OF TY 4 TRANSCRIPTION ELONGATION FACTOR SPT4 RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006135.3|UniProtKB=G3QTH9 G3QTH9 AIM2 PTHR12200:SF17 INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER INTERFERON-INDUCIBLE PROTEIN AIM2 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 response to cytokine#GO:0034097;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of innate immune response#GO:0045089;regulation of innate immune response#GO:0045088;positive regulation of response to external stimulus#GO:0032103;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;canonical inflammasome complex#GO:0061702;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010181.3|UniProtKB=G3RN34 G3RN34 LOC101152766 PTHR24300:SF23 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2S1 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;olefinic compound metabolic process#GO:0120254;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;xenobiotic metabolic process#GO:0006805;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000024460.2|UniProtKB=G3RPR1 G3RPR1 LANCL3 PTHR12736:SF29 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 3 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of cellular response to alcohol#GO:1905957;regulation of biological process#GO:0050789;regulation of response to alcohol#GO:1901419;regulation of abscisic acid-activated signaling pathway#GO:0009787;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 GORGO|Ensembl=ENSGGOG00000011606.3|UniProtKB=G3R7I8 G3R7I8 FBXO11 PTHR22990:SF20 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 11 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000010681.3|UniProtKB=G3R551 G3R551 GTF3C6 PTHR21860:SF2 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 6-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 6 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription by RNA polymerase III#GO:0006383;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;transcription factor TFIIIC complex#GO:0000127 GORGO|Ensembl=ENSGGOG00000002923.3|UniProtKB=G3S811 G3S811 LETM1 PTHR14009:SF8 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;calcium ion transport#GO:0006816;mitochondrial calcium ion transmembrane transport#GO:0006851;organelle organization#GO:0006996;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;mitochondrion organization#GO:0007005;monoatomic cation transmembrane transport#GO:0098655;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular component organization#GO:0016043;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012097.3|UniProtKB=A0A2I2ZRJ8 A0A2I2ZRJ8 EIF6 PTHR10784:SF0 TRANSLATION INITIATION FACTOR 6 EUKARYOTIC TRANSLATION INITIATION FACTOR 6 ribonucleoprotein complex binding#GO:0043021;ribosomal large subunit binding#GO:0043023;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;organelle assembly#GO:0070925;nuclear export#GO:0051168;rRNA processing#GO:0006364;nuclear transport#GO:0051169;protein-RNA complex assembly#GO:0022618;localization#GO:0051179;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA#GO:0000470;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;rRNA metabolic process#GO:0016072;intracellular transport#GO:0046907;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;establishment of organelle localization#GO:0051656;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000015264.3|UniProtKB=G3RGY0 G3RGY0 MAGEA10 PTHR11736:SF153 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 10 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003758.3|UniProtKB=G3RUN4 G3RUN4 WHRN PTHR23116:SF37 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED WHIRLIN animal organ morphogenesis#GO:0009887;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;embryonic organ development#GO:0048568;system development#GO:0048731;anatomical structure development#GO:0048856;inner ear development#GO:0048839;plasma membrane bounded cell projection organization#GO:0120036;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;developmental process#GO:0032502;sensory organ development#GO:0007423;epidermis development#GO:0008544;system process#GO:0003008;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;inner ear receptor cell stereocilium organization#GO:0060122;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;sensory perception of sound#GO:0007605;sensory organ morphogenesis#GO:0090596;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;nervous system process#GO:0050877;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;ear development#GO:0043583;cellular process#GO:0009987;inner ear morphogenesis#GO:0042472;neuron projection development#GO:0031175;hair cell differentiation#GO:0035315;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;embryo development#GO:0009790;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;stereocilium#GO:0032420;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000009664.3|UniProtKB=G3SIZ4 G3SIZ4 SH3BGRL PTHR12232:SF5 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN ADAPTER SH3BGRL ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;protein-RNA adaptor activity#GO:0140517 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;proteasomal protein catabolic process#GO:0010498;positive regulation of macromolecule metabolic process#GO:0010604;protein catabolic process#GO:0030163;regulation of translational initiation#GO:0006446;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000040253.1|UniProtKB=A0A2I2YF57 A0A2I2YF57 PTHR45722:SF37 60S RIBOSOMAL PROTEIN L35 LARGE RIBOSOMAL SUBUNIT PROTEIN UL29 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000015312.3|UniProtKB=G3RH21 G3RH21 PRSS33 PTHR24253:SF58 TRANSMEMBRANE PROTEASE SERINE TRYPTASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008696.3|UniProtKB=A0A2I2Y3S7 A0A2I2Y3S7 METAP2 PTHR45777:SF2 METHIONINE AMINOPEPTIDASE 2 METHIONINE AMINOPEPTIDASE 2 exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000043912.1|UniProtKB=G3SBB8 G3SBB8 PTHR24257:SF22 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 3B peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007726.3|UniProtKB=G3QXK8 G3QXK8 PRKRIP1 PTHR13507:SF0 PRKR-INTERACTING PROTEIN 1 PRKR-INTERACTING PROTEIN 1 enzyme inhibitor activity#GO:0004857;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase inhibitor activity#GO:0019210;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;enzyme regulator activity#GO:0030234 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000004783.3|UniProtKB=G3RVG2 G3RVG2 FAM117A PTHR14972:SF7 AGAP011572-PA PROTEIN FAM117A GORGO|Ensembl=ENSGGOG00000001475.3|UniProtKB=G3QGJ9 G3QGJ9 GPC1 PTHR10822:SF8 GLYPICAN GLYPICAN-1 growth factor binding#GO:0019838;protein binding#GO:0005515;fibroblast growth factor binding#GO:0017134;binding#GO:0005488 negative regulation of response to stimulus#GO:0048585;cell migration#GO:0016477;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of protein localization#GO:0032880;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell surface#GO:0009986;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000041410.1|UniProtKB=G3QLD9 G3QLD9 HSD3B2 PTHR10366:SF784 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3 BETA-HYDROXYSTEROID DEHYDROGENASE_DELTA 5--4-ISOMERASE TYPE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;steroid biosynthetic process#GO:0006694;regulation of biological quality#GO:0065008;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;lyase#PC00144;dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000016866.3|UniProtKB=A0A2I2Z3L2 A0A2I2Z3L2 PTHR21588:SF19 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 3 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;membrane organization#GO:0061024 mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000007517.3|UniProtKB=G3RT87 G3RT87 EED PTHR10253:SF12 POLYCOMB PROTEIN POLYCOMB PROTEIN EED chromatin binding#GO:0003682;binding#GO:0005488;molecular function activator activity#GO:0140677;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772 negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000003193.3|UniProtKB=G3QL02 G3QL02 MRPS35 PTHR13490:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN MS35 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000012363.3|UniProtKB=G3R9I9 G3R9I9 ZER1 PTHR12904:SF23 FAMILY NOT NAMED PROTEIN ZER-1 HOMOLOG Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000006781.3|UniProtKB=G3QV86 G3QV86 PHKA1 PTHR10749:SF4 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, SKELETAL MUSCLE ISOFORM cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 GORGO|Ensembl=ENSGGOG00000041777.1|UniProtKB=A0A2I2ZQU8 A0A2I2ZQU8 PTHR10031:SF55 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE LIPID-BINDING PROTEIN transporter#PC00227;primary active transporter#PC00068;ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000015452.3|UniProtKB=G3S8T6 G3S8T6 FAM107A PTHR16768:SF3 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A ACTIN-ASSOCIATED PROTEIN FAM107A actin filament bundle organization#GO:0061572;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actin filament polymerization#GO:0030041;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;regulation of actin filament-based process#GO:0032970;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 actomyosin#GO:0042641;neuron projection#GO:0043005;intracellular membraneless organelle#GO:0043232;stress fiber#GO:0001725;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;actin cytoskeleton#GO:0015629;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000016797.3|UniProtKB=G3RKW0 G3RKW0 LOC101135790 PTHR45615:SF50 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-16 isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000015154.3|UniProtKB=G3RGP4 G3RGP4 MRC1 PTHR22803:SF104 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED MACROPHAGE MANNOSE RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000005164.3|UniProtKB=G3QR24 G3QR24 GPR139 PTHR46272:SF3 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G PROTEIN-COUPLED RECEPTOR 139-RELATED signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186 GORGO|Ensembl=ENSGGOG00000038727.1|UniProtKB=A0A2I2ZI40 A0A2I2ZI40 LOC101129206 PTHR10496:SF21 40S RIBOSOMAL PROTEIN S24 40S RIBOSOMAL PROTEIN S24 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010016.3|UniProtKB=G3R3F7 G3R3F7 SLC9A5 PTHR10110:SF56 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 5 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000013905.3|UniProtKB=G3RZ49 G3RZ49 NUP155 PTHR10350:SF6 NUCLEAR PORE COMPLEX PROTEIN NUP155 NUCLEAR PORE COMPLEX PROTEIN NUP155 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;localization within membrane#GO:0051668;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;protein localization to organelle#GO:0033365 nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006213.3|UniProtKB=G3QTP3 G3QTP3 HESX1 PTHR46966:SF1 HOMEOBOX EXPRESSED IN ES CELLS 1 HOMEOBOX EXPRESSED IN ES CELLS 1 DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;nervous system development#GO:0007399;head development#GO:0060322;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;forebrain development#GO:0030900;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000009958.3|UniProtKB=G3S2G9 G3S2G9 RPL7L1 PTHR11524:SF13 60S RIBOSOMAL PROTEIN L7 RIBOSOMAL PROTEIN UL30-LIKE structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000022354.2|UniProtKB=G3SGX8 G3SGX8 SARAF PTHR15929:SF0 STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of transport#GO:0051049;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 GORGO|Ensembl=ENSGGOG00000015460.3|UniProtKB=A0A2I2YCN6 A0A2I2YCN6 WLS PTHR13449:SF2 INTEGRAL MEMBRANE PROTEIN GPR177 PROTEIN WNTLESS HOMOLOG binding#GO:0005488;protein binding#GO:0005515;Wnt-protein binding#GO:0017147 regulation of biological process#GO:0050789;protein localization to extracellular region#GO:0071692;signaling#GO:0023052;export from cell#GO:0140352;signal release#GO:0023061;localization#GO:0051179;protein secretion#GO:0009306;cell communication#GO:0007154;cellular localization#GO:0051641;secretion#GO:0046903;secretion by cell#GO:0032940;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020 GORGO|Gene=1C03_GORGO|UniProtKB=P30386 P30386 PTHR16675:SF294 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, C ALPHA CHAIN protein binding#GO:0005515;antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488;signaling receptor binding#GO:0005102 antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of cellular process#GO:0048522 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000000607.3|UniProtKB=G3QEA5 G3QEA5 SH3BGRL3 PTHR12232:SF3 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 3 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000007302.3|UniProtKB=G3QWI8 G3QWI8 POLR3D PTHR13408:SF0 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012948.3|UniProtKB=G3RAZ1 G3RAZ1 NAA11 PTHR23091:SF282 N-TERMINAL ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 11 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000013226.3|UniProtKB=G3RBP0 G3RBP0 CBY1 PTHR21533:SF20 LEUCINE-RICH PROTEIN PROTEIN CHIBBY HOMOLOG 1 regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005548.3|UniProtKB=G3QS16 G3QS16 DTNBP1 PTHR16294:SF5 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN establishment of vesicle localization#GO:0051650;regulation of localization#GO:0032879;regulation of transport#GO:0051049;microtubule-based process#GO:0007017;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of neurotransmitter secretion#GO:0046928;generation of neurons#GO:0048699;regulation of secretion by cell#GO:1903530;vesicle localization#GO:0051648;axo-dendritic transport#GO:0008088;regulation of signal transduction#GO:0009966;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;anterograde synaptic vesicle transport#GO:0048490;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;axonal transport#GO:0098930;organelle localization#GO:0051640;system development#GO:0048731;anterograde axonal transport#GO:0008089;regulation of secretion#GO:0051046;localization#GO:0051179;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;synaptic vesicle transport#GO:0048489;endomembrane system organization#GO:0010256;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;synaptic vesicle localization#GO:0097479;regulation of trans-synaptic signaling#GO:0099177;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of synaptic vesicle exocytosis#GO:2000300;cell development#GO:0048468;establishment of organelle localization#GO:0051656;microtubule-based transport#GO:0099111;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular localization#GO:0051641;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;vesicle cytoskeletal trafficking#GO:0099518;neurogenesis#GO:0022008;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;regulation of exocytosis#GO:0017157;anatomical structure development#GO:0048856 cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular vesicle#GO:0097708;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane#GO:0005886;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;BLOC-1 complex#GO:0031083;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000015986.3|UniProtKB=G3RIU0 G3RIU0 ALG6 PTHR12413:SF1 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000005495.3|UniProtKB=G3QRW9 G3QRW9 RBL1 PTHR13742:SF20 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-LIKE PROTEIN 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular developmental process#GO:0048869;negative regulation of cell cycle#GO:0045786;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;developmental process#GO:0032502;negative regulation of mitotic cell cycle phase transition#GO:1901991;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789 transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway feedback loops 2#P04398>Rb#P04654 GORGO|Ensembl=ENSGGOG00000002917.3|UniProtKB=G3RPD8 G3RPD8 FGFR4 PTHR24416:SF343 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 4 transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;fibroblast growth factor binding#GO:0017134;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740 regulation of biosynthetic process#GO:0009889;positive regulation of MAPK cascade#GO:0043410;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;fibroblast growth factor receptor signaling pathway#GO:0008543;regulation of steroid biosynthetic process#GO:0050810;regulation of lipid biosynthetic process#GO:0046890;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of lipid metabolic process#GO:0019216;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;regulation of ERK1 and ERK2 cascade#GO:0070372;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 GORGO|Ensembl=ENSGGOG00000028397.2|UniProtKB=A0A2I2ZXJ9 A0A2I2ZXJ9 LOC101143171 PTHR31586:SF2 CYTOCHROME C OXIDASE PROTEIN 20 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000014611.3|UniProtKB=G3RFB4 G3RFB4 PDE2A PTHR11347:SF102 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC PHOSPHODIESTERASE PDE-2-RELATED protein binding#GO:0005515;hydrolase activity#GO:0016787;binding#GO:0005488;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;identical protein binding#GO:0042802;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 positive regulation of biological process#GO:0048518;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;positive regulation of macromolecule metabolic process#GO:0010604;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;phosphorus metabolic process#GO:0006793;regulation of cellular component organization#GO:0051128;small molecule metabolic process#GO:0044281;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;ribonucleotide metabolic process#GO:0009259;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nucleotide metabolic process#GO:0009117;negative regulation of intracellular signal transduction#GO:1902532;ribonucleotide catabolic process#GO:0009261;positive regulation of cellular process#GO:0048522;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cyclic nucleotide metabolic process#GO:0009187;regulation of response to stimulus#GO:0048583;nucleotide catabolic process#GO:0009166;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;purine ribonucleotide catabolic process#GO:0009154;regulation of mitochondrion organization#GO:0010821;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide catabolic process#GO:0006195;positive regulation of biosynthetic process#GO:0009891;organophosphate catabolic process#GO:0046434 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;plasma membrane region#GO:0098590;organelle outer membrane#GO:0031968;plasma membrane#GO:0005886;mitochondrial inner membrane#GO:0005743;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;synaptic membrane#GO:0097060;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;organelle inner membrane#GO:0019866;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;outer membrane#GO:0019867;mitochondrial matrix#GO:0005759;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;mitochondrion#GO:0005739 hydrolase#PC00121;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000042116.1|UniProtKB=A0A2I2YHZ7 A0A2I2YHZ7 SIT1 PTHR15604:SF0 SIGNALING THRESHOLD-REGULATING TRANSMEMBRANE ADAPTER 1 SIGNALING THRESHOLD-REGULATING TRANSMEMBRANE ADAPTER 1 enzyme binding#GO:0019899;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;binding#GO:0005488;protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515 regulation of T cell activation#GO:0050863;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022776.2|UniProtKB=G3S5J5 G3S5J5 TMEM248 PTHR16002:SF5 TRANSMEMBRANE PROTEIN 248-LIKE TRANSMEMBRANE PROTEIN 248 GORGO|Ensembl=ENSGGOG00000011910.3|UniProtKB=G3R8C2 G3R8C2 MORC4 PTHR23336:SF22 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000000434.3|UniProtKB=G3QDU9 G3QDU9 EIF5A2 PTHR11673:SF13 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-2 translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000003168.3|UniProtKB=G3QKX8 G3QKX8 BLOC1S1 PTHR43313:SF12 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 5 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;cytoplasm#GO:0005737 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000998.3|UniProtKB=G3QFB7 G3QFB7 PLEKHM3 PTHR12326:SF10 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 3 GORGO|Ensembl=ENSGGOG00000007265.3|UniProtKB=G3QWF2 G3QWF2 MEA1 PTHR17005:SF3 MALE-ENHANCED ANTIGEN-1 MALE-ENHANCED ANTIGEN 1 GORGO|Ensembl=ENSGGOG00000015344.3|UniProtKB=G3RH58 G3RH58 OSBPL7 PTHR10972:SF85 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 7 binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934;alcohol binding#GO:0043178;lipid binding#GO:0008289;cholesterol binding#GO:0015485;steroid binding#GO:0005496 endomembrane system#GO:0012505;nuclear envelope#GO:0005635;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000014599.3|UniProtKB=G3S715 G3S715 RICTOR PTHR13298:SF11 CYTOSOLIC REGULATOR PIANISSIMO RAPAMYCIN-INSENSITIVE COMPANION OF MTOR protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 TORC2 signaling#GO:0038203;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of response to stimulus#GO:0048584;TOR signaling#GO:0031929;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000002839.3|UniProtKB=G3QK28 G3QK28 IRF2BPL PTHR10816:SF14 MYELIN TRANSCRIPTION FACTOR 1-RELATED E3 UBIQUITIN-PROTEIN LIGASE IRF2BPL-RELATED transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000003128.3|UniProtKB=G3QKV2 G3QKV2 COL4A3 PTHR24023:SF1070 COLLAGEN ALPHA COLLAGEN ALPHA-3(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000026058.2|UniProtKB=G3S8F5 G3S8F5 PTHR11375:SF19 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000005183.3|UniProtKB=G3QR41 G3QR41 BMP3 PTHR11848:SF144 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 3 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000014356.3|UniProtKB=G3REL5 G3REL5 BCORL1 PTHR24117:SF6 AGAP007537-PB BCL-6 COREPRESSOR-LIKE PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000016779.3|UniProtKB=A0A2I2ZGK4 A0A2I2ZGK4 DCLK3 PTHR24347:SF427 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK3 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000024991.2|UniProtKB=A0A2I2YGR4 A0A2I2YGR4 PABPC4L PTHR24012:SF776 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 4-LIKE single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;binding#GO:0005488;nucleic acid binding#GO:0003676 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015400.3|UniProtKB=G3RHA7 G3RHA7 SERINC3 PTHR10383:SF51 SERINE INCORPORATOR SERINE INCORPORATOR 3 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000024651.2|UniProtKB=G3RZH1 G3RZH1 PTHR14057:SF10 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000002055.3|UniProtKB=G3QI26 G3QI26 KLF6 PTHR23235:SF50 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004827.3|UniProtKB=G3QQ77 G3QQ77 NSMAF PTHR13743:SF123 BEIGE/BEACH-RELATED PROTEIN FAN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009957.3|UniProtKB=A0A2I2YKD6 A0A2I2YKD6 FXR1 PTHR10603:SF6 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN RNA-BINDING PROTEIN FXR1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;positive regulation of macromolecule metabolic process#GO:0010604;regulation of trans-synaptic signaling#GO:0099177;positive regulation of cell differentiation#GO:0045597;regulation of mRNA metabolic process#GO:1903311;animal organ development#GO:0048513;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;positive regulation of nervous system development#GO:0051962;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of translation#GO:0006417;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nitrogen compound transport#GO:0071705;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;transport#GO:0006810;regulation of cell differentiation#GO:0045595;regulation of synaptic plasticity#GO:0048167;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;regulation of neurogenesis#GO:0050767;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;modulation of chemical synaptic transmission#GO:0050804;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound transport#GO:0015931;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;RNA localization#GO:0006403;regulation of RNA stability#GO:0043487;positive regulation of translation#GO:0045727;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;nucleic acid transport#GO:0050657;regulation of nervous system development#GO:0051960 nucleus#GO:0005634;neuron projection#GO:0043005;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000039585.1|UniProtKB=A0A2I2YCJ8 A0A2I2YCJ8 TIMM23 PTHR15371:SF34 TIM23 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM23B transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transmembrane protein transporter activity#GO:0008320 macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031 organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967 transporter#PC00227;secondary carrier transporter#PC00258;amino acid transporter#PC00046 GORGO|Ensembl=ENSGGOG00000008925.3|UniProtKB=A0A2I2Z9I5 A0A2I2Z9I5 PACC1 PTHR16087:SF0 TRANSMEMBRANE PROTEIN 206 PROTON-ACTIVATED CHLORIDE CHANNEL GORGO|Ensembl=ENSGGOG00000012647.3|UniProtKB=G3RA76 G3RA76 PTHR15044:SF0 NEUROPEPTIDE FF PRO-FMRFAMIDE-RELATED NEUROPEPTIDE FF molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;neuropeptide hormone activity#GO:0005184;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of blood pressure#GO:0008217;immune response#GO:0006955;defense response#GO:0006952;system process#GO:0003008;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission, postsynaptic#GO:0099565;chemical synaptic transmission#GO:0007268;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;regulation of postsynaptic membrane potential#GO:0060078;cell communication#GO:0007154;acute inflammatory response#GO:0002526;circulatory system process#GO:0003013;trans-synaptic signaling#GO:0099537;inflammatory response#GO:0006954;response to stress#GO:0006950;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;positive regulation of blood pressure#GO:0045777;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;nervous system process#GO:0050877 axon terminus#GO:0043679;cell junction#GO:0030054;extracellular region#GO:0005576;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;somatodendritic compartment#GO:0036477;neuron projection terminus#GO:0044306;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;presynapse#GO:0098793;neuron projection#GO:0043005 GORGO|Ensembl=ENSGGOG00000021985.2|UniProtKB=G3SG29 G3SG29 PTHR43329:SF4 EPOXIDE HYDROLASE SERINE HYDROLASE-LIKE PROTEIN-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000016906.3|UniProtKB=A0A2I2ZS62 A0A2I2ZS62 FASTK PTHR21228:SF4 FAST LEU-RICH DOMAIN-CONTAINING FAS-ACTIVATED SERINE_THREONINE KINASE binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;regulation of RNA stability#GO:0043487;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;regulation of RNA metabolic process#GO:0051252 membraneless organelle#GO:0043228;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000004547.3|UniProtKB=G3QPG3 G3QPG3 SCRN2 PTHR12994:SF16 SECERNIN SECERNIN-2 GORGO|Ensembl=ENSGGOG00000026248.2|UniProtKB=G3SB40 G3SB40 GNB4 PTHR19850:SF28 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-4 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562 G-protein#PC00020;heterotrimeric G-protein#PC00117;protein-binding activity modulator#PC00095 Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;GABA-B receptor II signaling#P05731>Gbeta#P05755;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Wnt signaling pathway#P00057>GBeta#P01457;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;PI3 kinase pathway#P00048>Gbetagamma#P01188;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Endogenous cannabinoid signaling#P05730>Gbeta#P05745 GORGO|Ensembl=ENSGGOG00000026511.2|UniProtKB=G3SEN8 G3SEN8 LOC101141967 PTHR21633:SF10 IQ MOTIF CONTAINING F IQ MOTIF CONTAINING F4 GORGO|Ensembl=ENSGGOG00000011784.3|UniProtKB=G3R7Z0 G3R7Z0 TGIF2 PTHR11850:SF412 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000023158.2|UniProtKB=A0A2I2ZIY0 A0A2I2ZIY0 CLDN11 PTHR12002:SF6 CLAUDIN CLAUDIN-11 cell adhesion#GO:0007155;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330 apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000017053.4|UniProtKB=G3RLK0 G3RLK0 MYO16 PTHR47335:SF1 UNCONVENTIONAL MYOSIN-XVI UNCONVENTIONAL MYOSIN-XVI intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;system development#GO:0048731 actin cytoskeleton#GO:0015629;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;myosin complex#GO:0016459;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000005976.3|UniProtKB=G3QT45 G3QT45 NIN PTHR18905:SF11 NINEIN NINEIN protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;centrosome localization#GO:0051642;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule anchoring#GO:0034453;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393 spindle pole#GO:0000922;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;mitotic spindle#GO:0072686;cell projection#GO:0042995;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary transition fiber#GO:0097539;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535 PDGF signaling pathway#P00047>GSK3#P01153 GORGO|Ensembl=ENSGGOG00000015274.3|UniProtKB=A0A2I2ZSU6 A0A2I2ZSU6 DMRTC2 PTHR12322:SF126 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR C2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;sex differentiation#GO:0007548;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008607.3|UniProtKB=G3RSY1 G3RSY1 ZNF235 PTHR24381:SF488 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 227 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000012499.3|UniProtKB=G3R9U4 G3R9U4 SNRPC PTHR31148:SF1 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000027111.2|UniProtKB=G3RSA6 G3RSA6 ATP1B3 PTHR11523:SF47 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000039058.1|UniProtKB=A0A2I2YI38 A0A2I2YI38 PTHR11711:SF139 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4A small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 GORGO|Gene=OR1G1|UniProtKB=Q9TU86 Q9TU86 OR1G1 PTHR48018:SF105 OLFACTORY RECEPTOR OLFACTORY RECEPTOR OR9H1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004526.3|UniProtKB=G3QPE7 G3QPE7 UTP4 PTHR44163:SF1 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;t-UTP complex#GO:0034455;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000013142.3|UniProtKB=G3SH62 G3SH62 KCNC4 PTHR11537:SF126 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL KCNC4 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;action potential#GO:0001508 cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;postsynaptic membrane#GO:0045211;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell body#GO:0044297;postsynapse#GO:0098794;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;presynapse#GO:0098793;cell leading edge#GO:0031252;transmembrane transporter complex#GO:1902495;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;neuron projection terminus#GO:0044306;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;axon terminus#GO:0043679;neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000012866.3|UniProtKB=A0A2I2Y2L4 A0A2I2Y2L4 FKBP8 PTHR46512:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP8 macromolecule metabolic process#GO:0043170;positive regulation of BMP signaling pathway#GO:0030513;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of BMP signaling pathway#GO:0030510;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;protein folding#GO:0006457;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000007627.3|UniProtKB=A0A2I2ZE79 A0A2I2ZE79 BTBD6 PTHR24410:SF24 HL07962P-RELATED BTB (POZ) DOMAIN CONTAINING 6B defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000041808.1|UniProtKB=A0A2I2Y4Q0 A0A2I2Y4Q0 LOC101150640 PTHR23428:SF364 HISTONE H2B HISTONE H2B TYPE 2-F humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000036913.1|UniProtKB=A0A2I2ZSA5 A0A2I2ZSA5 TMEM265 PTHR48581:SF1 TRANSMEMBRANE PROTEIN 265 TRANSMEMBRANE PROTEIN 265 GORGO|Ensembl=ENSGGOG00000015523.3|UniProtKB=G3RHM6 G3RHM6 LOC101126302 PTHR10648:SF7 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1 LIKE (PSEUDO structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000004840.3|UniProtKB=G3QQ82 G3QQ82 CSRP1 PTHR24215:SF23 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198 actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;tissue development#GO:0009888;cellular developmental process#GO:0048869;developmental process#GO:0032502 Z disc#GO:0030018;nucleus#GO:0005634;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000014615.3|UniProtKB=G3RF94 G3RF94 DDX59 PTHR47958:SF30 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX59-RELATED ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000013855.3|UniProtKB=G3RDB5 G3RDB5 NDEL1 PTHR10921:SF0 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;centrosome localization#GO:0051642;establishment or maintenance of cell polarity#GO:0007163;nuclear division#GO:0000280;microtubule-based transport#GO:0099111;spindle localization#GO:0051653;cellular localization#GO:0051641;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of mitotic spindle localization#GO:0040001;regulation of neuron projection development#GO:0010975;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;organelle transport along microtubule#GO:0072384;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;cell motility#GO:0048870;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;supramolecular fiber organization#GO:0097435;microtubule polymerization or depolymerization#GO:0031109;establishment of spindle localization#GO:0051293;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810;regulation of plasma membrane bounded cell projection organization#GO:0120035;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;establishment of mitotic spindle orientation#GO:0000132;vesicle cytoskeletal trafficking#GO:0099518;mitotic cell cycle process#GO:1903047;microtubule polymerization#GO:0046785 microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule organizing center#GO:0005815;centrosome#GO:0005813;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000023506.2|UniProtKB=G3SHV7 G3SHV7 PTHR23143:SF19 TRICHOHYALIN-RELATED GOLGIN A6 FAMILY LIKE 10-RELATED actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000000906.4|UniProtKB=G3QF31 G3QF31 TXNDC5 PTHR45672:SF3 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5 isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000006726.3|UniProtKB=G3QV23 G3QV23 PDIA5 PTHR45672:SF2 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED PROTEIN DISULFIDE-ISOMERASE A5 protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000041100.1|UniProtKB=A0A2I2Y7C8 A0A2I2Y7C8 ATG14 PTHR13664:SF0 BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein-membrane adaptor activity#GO:0043495;kinase regulator activity#GO:0019207;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein-containing complex disassembly#GO:0032984;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;cellular component organization#GO:0016043;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;cellular component disassembly#GO:0022411;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;organelle localization#GO:0051640;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;cellular response to nutrient levels#GO:0031669;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;phosphatidylinositol 3-kinase complex, class III#GO:0035032;transferase complex, transferring phosphorus-containing groups#GO:0061695;autophagosome#GO:0005776;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;extrinsic component of membrane#GO:0019898;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000000083.3|UniProtKB=G3QCX9 G3QCX9 ZP2 PTHR23343:SF4 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899 cell-cell recognition#GO:0009988;binding of sperm to zona pellucida#GO:0007339;cell recognition#GO:0008037;cell activation#GO:0001775;sexual reproduction#GO:0019953;sperm-egg recognition#GO:0035036;fertilization#GO:0009566;reproductive process#GO:0022414;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of reproductive process#GO:2000241;cellular process#GO:0009987;regulation of biological process#GO:0050789;single fertilization#GO:0007338;negative regulation of biological process#GO:0048519 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009983.3|UniProtKB=G3R3C3 G3R3C3 NUTM2F PTHR22879:SF2 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 2F-RELATED GORGO|Ensembl=ENSGGOG00000004793.3|UniProtKB=G3SK41 G3SK41 NRDC PTHR43690:SF40 NARDILYSIN NARDILYSIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000009296.3|UniProtKB=G3R1K8 G3R1K8 HEXB PTHR22600:SF38 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE SUBUNIT BETA hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycosaminoglycan metabolic process#GO:0030203;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;protein N-linked glycosylation#GO:0006487;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;carbohydrate derivative catabolic process#GO:1901136;aminoglycan metabolic process#GO:0006022;ceramide metabolic process#GO:0006672;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;glycoprotein metabolic process#GO:0009100;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;membrane#GO:0016020;cell periphery#GO:0071944;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000003080.3|UniProtKB=G3QKP9 G3QKP9 FANCB PTHR28450:SF1 FANCONI ANEMIA GROUP B PROTEIN FANCONI ANEMIA GROUP B PROTEIN positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;regulation of double-strand break repair via homologous recombination#GO:0010569;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;double-strand break repair via homologous recombination#GO:0000724;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of macromolecule metabolic process#GO:0010604;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of double-strand break repair#GO:2000779;recombinational repair#GO:0000725;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of double-strand break repair#GO:2000781;negative regulation of DNA recombination#GO:0045910;primary metabolic process#GO:0044238;positive regulation of DNA metabolic process#GO:0051054;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA metabolic process#GO:0051053;positive regulation of DNA repair#GO:0045739;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000010281.3|UniProtKB=G3R442 G3R442 FAM168A PTHR31844:SF1 MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR-RELATED PROTEIN FAM168A regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;positive regulation of DNA metabolic process#GO:0051054;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 structural protein#PC00211;myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000024556.2|UniProtKB=G3RX03 G3RX03 PTHR12884:SF42 60S RIBOSOMAL PROTEIN L29 LARGE RIBOSOMAL SUBUNIT PROTEIN EL29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000038540.1|UniProtKB=A0A2I2YX53 A0A2I2YX53 PTHR11587:SF6 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000004408.3|UniProtKB=A0A2I2ZNY8 A0A2I2ZNY8 PXN PTHR24216:SF11 PAXILLIN-RELATED PAXILLIN protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell adhesion#GO:0007155;response to transforming growth factor beta#GO:0071559;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;endothelial cell migration#GO:0043542;cell migration#GO:0016477;substrate adhesion-dependent cell spreading#GO:0034446;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Integrin signalling pathway#P00034>Paxillin#P00950;Gonadotropin-releasing hormone receptor pathway#P06664>Paxillin#P06784;CCKR signaling map#P06959>Paxillin#P07145;Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418 GORGO|Ensembl=ENSGGOG00000014881.3|UniProtKB=G3SIC0 G3SIC0 CXCR3 PTHR10489:SF671 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 3 protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;chemotaxis#GO:0006935;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000013445.3|UniProtKB=G3RC92 G3RC92 SMCO2 PTHR22422:SF5 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5B-RELATED SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000011374.3|UniProtKB=A0A2I2ZMI7 A0A2I2ZMI7 PUM2 PTHR12537:SF52 RNA BINDING PROTEIN PUMILIO-RELATED PUMILIO HOMOLOG 2 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000042124.1|UniProtKB=A0A2I2ZAS3 A0A2I2ZAS3 FAM240A PTHR40387:SF3 PROTEIN FAM240B PROTEIN FAM240A GORGO|Ensembl=ENSGGOG00000008211.3|UniProtKB=A0A2I2YN73 A0A2I2YN73 CPSF6 PTHR23204:SF3 CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;nucleus#GO:0005634 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006394.3|UniProtKB=G3QU58 G3QU58 DPH7 PTHR46042:SF1 DIPHTHINE METHYLTRANSFERASE DIPHTHINE METHYLTRANSFERASE protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000014422.3|UniProtKB=G3RES8 G3RES8 NMT1 PTHR11377:SF7 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000034867.2|UniProtKB=G3SKP1 G3SKP1 AXDND1 PTHR23052:SF1 AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1 AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008471.3|UniProtKB=G3QZH0 G3QZH0 DHRS7B PTHR44196:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B PEROXISOMAL REDUCTASE ACTIVATING PPAR-GAMMA cellular anatomical structure#GO:0110165;membrane#GO:0016020 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000015646.3|UniProtKB=G3RHY3 G3RHY3 C21H20orf202 PTHR32289:SF5 PROTEIN FAM167A TRANSMEMBRANE 74B, OPPOSITE STRAND GORGO|Ensembl=ENSGGOG00000039771.1|UniProtKB=A0A2I2Y4R9 A0A2I2Y4R9 PTHR23268:SF89 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000042895.1|UniProtKB=A0A2I2Z051 A0A2I2Z051 PTHR15001:SF12 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 125 immune system process#GO:0002376;cell killing#GO:0001906;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000004652.3|UniProtKB=G3SFW1 G3SFW1 NRBP2 PTHR13902:SF53 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN 2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system development#GO:0048731;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000005559.3|UniProtKB=G3QS23 G3QS23 BCAP31 PTHR12701:SF15 BCR-ASSOCIATED PROTEIN, BAP B-CELL RECEPTOR-ASSOCIATED PROTEIN 31 molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;protein carrier activity#GO:0140597 regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;positive regulation of metabolic process#GO:0009893;protein transport#GO:0015031;positive regulation of protein metabolic process#GO:0051247;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;intracellular protein localization#GO:0008104;transport#GO:0006810;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;protein metabolic process#GO:0019538;localization#GO:0051179;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;primary metabolic process#GO:0044238;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006863.3|UniProtKB=G3QVE8 G3QVE8 SDF2L1 PTHR46809:SF1 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000025079.2|UniProtKB=G3S0W7 G3S0W7 LRRC8D PTHR45752:SF11 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8D monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 establishment of localization#GO:0051234;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;monoatomic ion transmembrane transport#GO:0034220;dicarboxylic acid transport#GO:0006835;biological regulation#GO:0065007;nitrogen compound transport#GO:0071705;aspartate transmembrane transport#GO:0015810;intracellular signal transduction#GO:0035556;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;cell communication#GO:0007154;carboxylic acid transmembrane transport#GO:1905039;regulation of cellular process#GO:0050794;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;carbohydrate derivative transport#GO:1901264;cellular response to stimulus#GO:0051716;monoatomic anion transport#GO:0006820;import into cell#GO:0098657;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;signal transduction#GO:0007165;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;signaling#GO:0023052;import across plasma membrane#GO:0098739;response to stimulus#GO:0050896;regulation of biological process#GO:0050789 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005298.3|UniProtKB=G3S2T2 G3S2T2 ZNF772 PTHR24381:SF304 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 587B DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000002900.3|UniProtKB=G3QK84 G3QK84 SP140L PTHR10417:SF9 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN SP140 NUCLEAR BODY PROTEIN DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007930.3|UniProtKB=G3QY35 G3QY35 MLF2 PTHR13105:SF4 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR 2 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000012150.4|UniProtKB=A0A2I2YVA2 A0A2I2YVA2 ZMYM4 PTHR45736:SF5 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 4 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016466.3|UniProtKB=G3RQW1 G3RQW1 HIVEP2 PTHR45944:SF1 SCHNURRI, ISOFORM F TRANSCRIPTION FACTOR HIVEP2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000038633.1|UniProtKB=A0A2I2Z6X5 A0A2I2Z6X5 LOC101145263 PTHR10768:SF46 60S RIBOSOMAL PROTEIN L37 60S RIBOSOMAL PROTEIN L37 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009198.3|UniProtKB=G3R1D4 G3R1D4 TRPC6 PTHR10117:SF7 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 6 channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215 intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480;homeostatic process#GO:0042592;metal ion transport#GO:0030001;reproductive process#GO:0022414;fertilization#GO:0009566;calcium ion homeostasis#GO:0055074;sexual reproduction#GO:0019953;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;single fertilization#GO:0007338;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 GORGO|Ensembl=ENSGGOG00000024564.2|UniProtKB=A0A2I2ZPE3 A0A2I2ZPE3 CD163 PTHR19331:SF441 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M130 cargo receptor activity#GO:0038024 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000002394.3|UniProtKB=G3QIY4 G3QIY4 GFUS PTHR43238:SF1 GDP-L-FUCOSE SYNTHASE GDP-L-FUCOSE SYNTHASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009487.3|UniProtKB=G3RTP5 G3RTP5 ZKSCAN4 PTHR23226:SF67 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000025436.2|UniProtKB=G3RR38 G3RR38 CD164L2 PTHR11337:SF11 MUCIN/PORIMIN CD164 SIALOMUCIN-LIKE 2 PROTEIN intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000010803.3|UniProtKB=G3R5H5 G3R5H5 UGGT2 PTHR11226:SF1 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 2 UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000005896.3|UniProtKB=G3QSX2 G3QSX2 TBCC PTHR15139:SF0 TUBULIN FOLDING COFACTOR C TUBULIN-SPECIFIC CHAPERONE C microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000034825.2|UniProtKB=A0A2I2ZQU0 A0A2I2ZQU0 TMPRSS6 PTHR24253:SF62 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 6 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000028370.2|UniProtKB=G3S4Q9 G3S4Q9 TMEM45B PTHR16007:SF59 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B GORGO|Ensembl=ENSGGOG00000010083.3|UniProtKB=G3R3L0 G3R3L0 TSPAN2 PTHR19282:SF155 TETRASPANIN TETRASPANIN-2 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039074.1|UniProtKB=A0A2I2ZDZ9 A0A2I2ZDZ9 OR7D1 PTHR48001:SF172 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015023.3|UniProtKB=G3RGB8 G3RGB8 ACOT2 PTHR10824:SF44 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COENZYME A THIOESTERASE 1-RELATED hydrolase activity#GO:0016787;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;deacylase activity#GO:0160215;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824 purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 peroxisome#GO:0005777;mitochondrion#GO:0005739;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000024707.2|UniProtKB=G3S3Q2 G3S3Q2 PTPDC1 PTHR23339:SF123 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE DOMAIN-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000026800.2|UniProtKB=A0A2I2ZPQ4 A0A2I2ZPQ4 TNPO1 PTHR10527:SF21 IMPORTIN BETA TRANSPORTIN-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013522.3|UniProtKB=G3RCG1 G3RCG1 LDLRAD4 PTHR16514:SF4 LOW DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING 4A LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488 negative regulation of signal transduction#GO:0009968;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;early endosome membrane#GO:0031901;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000014493.3|UniProtKB=G3REY7 G3REY7 RNF169 PTHR23328:SF2 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF169 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;chromatin binding#GO:0003682;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;ubiquitin-protein transferase activity#GO:0004842 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000012140.3|UniProtKB=G3R8X7 G3R8X7 SLC5A9 PTHR11819:SF96 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003037.3|UniProtKB=G3QKL3 G3QKL3 RAP1A PTHR24070:SF395 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1A hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of neurotransmitter transport#GO:0051588;regulation of secretion by cell#GO:1903530;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;intracellular signaling cassette#GO:0141124;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;regulation of exocytosis#GO:0017157;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;regulation of secretion#GO:0051046;cell communication#GO:0007154;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular response to nitrogen compound#GO:1901699;negative regulation of cellular process#GO:0048523 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 GORGO|Ensembl=ENSGGOG00000002843.3|UniProtKB=G3QK34 G3QK34 GNAS PTHR10218:SF348 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(S) SUBUNIT ALPHA ISOFORMS XLAS protein binding#GO:0005515;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;G protein-coupled receptor binding#GO:0001664 sensory perception of chemical stimulus#GO:0007606;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;renal absorption#GO:0070293;system process#GO:0003008;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;renal system process#GO:0003014;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234 heterotrimeric G-protein#PC00117;G-protein#PC00020 Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Endothelin signaling pathway#P00019>Gs#P00584;Enkephalin release#P05913>G-Protein (s)#P05977;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Gonadotropin-releasing hormone receptor pathway#P06664>gnas#P06717;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458 GORGO|Ensembl=ENSGGOG00000004467.3|UniProtKB=G3QP89 G3QP89 NPY1R PTHR24241:SF135 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000006473.3|UniProtKB=G3QUD2 G3QUD2 FXYD6 PTHR14132:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 6-RELATED transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of monoatomic ion transmembrane transport#GO:0034765 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015316.3|UniProtKB=G3RH27 G3RH27 PTHR12828:SF3 PROTEASOME MATURATION PROTEIN UMP1 PROTEASOME MATURATION PROTEIN cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000012976.3|UniProtKB=G3RW88 G3RW88 LOC109023079 PTHR24281:SF318 STEROID 21-HYDROXYLASE-RELATED STEROID 21-HYDROXYLASE tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;primary metabolic process#GO:0044238;cellular process#GO:0009987;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 hydroxylase#PC00122 GORGO|Ensembl=ENSGGOG00000023927.2|UniProtKB=G3RTF4 G3RTF4 TNFSF9 PTHR15153:SF0 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 9 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 9 tumor necrosis factor receptor superfamily binding#GO:0032813;protein binding#GO:0005515;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488 positive regulation of mononuclear cell proliferation#GO:0032946;regulation of leukocyte proliferation#GO:0070663;positive regulation of leukocyte activation#GO:0002696;positive regulation of cell differentiation#GO:0045597;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of biological process#GO:0048518;regulation of lymphocyte activation#GO:0051249;positive regulation of T cell proliferation#GO:0042102;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of leukocyte proliferation#GO:0070665;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;regulation of hemopoiesis#GO:1903706;positive regulation of lymphocyte proliferation#GO:0050671;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of T cell proliferation#GO:0042129;regulation of developmental process#GO:0050793;positive regulation of cell adhesion#GO:0045785 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000007780.3|UniProtKB=G3QXQ5 G3QXQ5 TSPAN15 PTHR19282:SF159 TETRASPANIN TETRASPANIN-15 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006978.3|UniProtKB=G3QVP6 G3QVP6 CCN1 PTHR11348:SF18 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 1 integrin binding#GO:0005178;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;carbohydrate derivative binding#GO:0097367;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;glycosaminoglycan binding#GO:0005539 cell adhesion#GO:0007155;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of cell motility#GO:2000147;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;biological regulation#GO:0065007 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 GORGO|Gene=FUT5|UniProtKB=Q8HYJ7 Q8HYJ7 FUT5 PTHR11929:SF11 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE FUT5 fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000014931.3|UniProtKB=A0A2I2Z288 A0A2I2Z288 CCSAP PTHR31022:SF4 CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;regulation of mitotic spindle assembly#GO:1901673;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of spindle organization#GO:0090224;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of spindle assembly#GO:0090169;regulation of mitotic spindle organization#GO:0060236;regulation of microtubule-based process#GO:0032886 microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoplasm#GO:0005737;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;axon#GO:0030424;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000040664.1|UniProtKB=A0A2I2Y407 A0A2I2Y407 PTHR12791:SF50 GOLGI SNARE BET1-RELATED BET1 HOMOLOG SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;Golgi organization#GO:0007030;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;membrane fusion#GO:0061025;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284 membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 SNARE protein#PC00034 GORGO|Ensembl=ENSGGOG00000040764.1|UniProtKB=A0A2I2ZR92 A0A2I2ZR92 PTHR22745:SF0 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic process#GO:0043066;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000022539.2|UniProtKB=G3SK68 G3SK68 PTHR10369:SF43 60S RIBOSOMAL PROTEIN L36A/L44 60S RIBOSOMAL PROTEIN L36A-LIKE structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005520.3|UniProtKB=G3QRY5 G3QRY5 GBX2 PTHR24334:SF3 HOMEOBOX PROTEIN GBX HOMEOBOX PROTEIN GBX-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000003610.3|UniProtKB=G3QM22 G3QM22 COQ2 PTHR11048:SF42 PRENYLTRANSFERASES 4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181 plasma membrane#GO:0005886;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;cell periphery#GO:0071944;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000028468.2|UniProtKB=G3RM37 G3RM37 TIGAR PTHR46517:SF1 FRUCTOSE-2,6-BISPHOSPHATASE TIGAR FRUCTOSE-2,6-BISPHOSPHATASE TIGAR phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of catabolic process#GO:0009895;regulation of carbohydrate metabolic process#GO:0006109;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 Cobalamin biosynthesis#P02735>Ribazole-5-phosphate phosphatase#P02881 GORGO|Ensembl=ENSGGOG00000001796.3|UniProtKB=G3SCP8 G3SCP8 STPG1 PTHR21580:SF21 SHIPPO-1-RELATED O(6)-METHYLGUANINE-INDUCED APOPTOSIS 2 cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;cellular component organization#GO:0016043;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of membrane permeability#GO:0090559;mitochondrion organization#GO:0007005;regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;apoptotic mitochondrial changes#GO:0008637 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000042178.1|UniProtKB=A0A2I2YBT7 A0A2I2YBT7 PTHR31036:SF0 FANCD2 OPPOSITE STRAND PROTEIN FANCD2 OPPOSITE STRAND PROTEIN regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216;negative regulation of metabolic process#GO:0009892;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of steroid biosynthetic process#GO:0050810;regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001455.3|UniProtKB=G3QGI0 G3QGI0 C1S PTHR24255:SF18 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1S SUBCOMPONENT serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000013496.3|UniProtKB=G3RCF2 G3RCF2 CHD3 PTHR45623:SF9 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD3 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ATP hydrolysis activity#GO:0016887;DNA binding#GO:0003677;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000015671.3|UniProtKB=G3RI10 G3RI10 TMOD2 PTHR10901:SF15 TROPOMODULIN TROPOMODULIN-2 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;cellular developmental process#GO:0048869;system process#GO:0003008;actin filament organization#GO:0007015;developmental process#GO:0032502;muscle contraction#GO:0006936;multicellular organismal process#GO:0032501;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987 contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000008312.3|UniProtKB=G3QZ21 G3QZ21 EIF1B PTHR10388:SF51 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1B translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000004880.3|UniProtKB=G3QQB8 G3QQB8 IDH2 PTHR11822:SF46 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;NADP+ metabolic process#GO:0006739;phosphorus metabolic process#GO:0006793 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010125.3|UniProtKB=G3R3P8 G3R3P8 CMKLR1 PTHR24225:SF49 CHEMOTACTIC RECEPTOR CHEMERIN-LIKE RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;taxis#GO:0042330;cell surface receptor signaling pathway#GO:0007166;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;positive regulation of immune response#GO:0050778;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte migration#GO:0002685;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cell communication#GO:0010646;locomotion#GO:0040011;regulation of calcium-mediated signaling#GO:0050848;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;chemotaxis#GO:0006935;regulation of granulocyte chemotaxis#GO:0071622;positive regulation of chemotaxis#GO:0050921;cell communication#GO:0007154;regulation of cell motility#GO:2000145 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000038295.1|UniProtKB=A0A2I2YI33 A0A2I2YI33 PTHR31423:SF3 YBAK DOMAIN-CONTAINING PROTEIN PROLYL-TRNA SYNTHETASE ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED GORGO|Ensembl=ENSGGOG00000008549.3|UniProtKB=G3QZP8 G3QZP8 PTHR10373:SF25 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell surface receptor signaling pathway#GO:0007166;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Wnt signaling pathway#P00057>TCF#P01437;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Gonadotropin-releasing hormone receptor pathway#P06664>TCF#P06701;Cadherin signaling pathway#P00012>TCF/LEF#P00465 GORGO|Ensembl=ENSGGOG00000027681.2|UniProtKB=A0A2I2YRL0 A0A2I2YRL0 YTHDF3 PTHR12357:SF9 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 3 protein-RNA adaptor activity#GO:0140517;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;RNA binding#GO:0003723 regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000000700.3|UniProtKB=G3QEJ0 G3QEJ0 PTHR19944:SF108 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1 BETA CHAIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823;protein-containing complex binding#GO:0044877 antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of leukocyte activation#GO:0002696;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;late endosome membrane#GO:0031902;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;vesicle membrane#GO:0012506 major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000013538.3|UniProtKB=G3RX38 G3RX38 LOC101133995 PTHR19944:SF59 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ ALPHA 1 CHAIN binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277;protein-containing complex binding#GO:0044877 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;regulation of immune response#GO:0050776;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;regulation of T cell activation#GO:0050863;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 GORGO|Ensembl=ENSGGOG00000016601.3|UniProtKB=G3RKD4 G3RKD4 CRB2 PTHR24049:SF19 CRUMBS FAMILY MEMBER PROTEIN CRUMBS HOMOLOG 2 cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000026567.2|UniProtKB=G3SGC2 G3SGC2 RPIA PTHR11934:SF0 RIBOSE-5-PHOSPHATE ISOMERASE RIBOSE-5-PHOSPHATE ISOMERASE isomerase activity#GO:0016853;ribose-5-phosphate isomerase activity#GO:0004751;intramolecular oxidoreductase activity#GO:0016860;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;generation of precursor metabolites and energy#GO:0006091;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;pentose-phosphate shunt, non-oxidative branch#GO:0009052;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide metabolic process#GO:0009117;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pentose-phosphate shunt#GO:0006098 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Pentose phosphate pathway#P02762>Ribulose 5-P Isomerase#P03071 GORGO|Ensembl=ENSGGOG00000025675.2|UniProtKB=G3S518 G3S518 EEF1A1 PTHR23115:SF222 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 1-RELATED translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000044172.1|UniProtKB=G3R6T8 G3R6T8 PAK6 PTHR45832:SF3 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE GORGO|Ensembl=ENSGGOG00000025804.2|UniProtKB=G3SHP9 G3SHP9 HMGA1 PTHR23341:SF1 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP PROTEIN HMG-I_HMG-Y transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000026285.2|UniProtKB=A0A2I2ZTG7 A0A2I2ZTG7 PTHR12138:SF165 PRIMATE-EXPANDED PROTEIN FAMILY SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000003774.3|UniProtKB=G3QMG9 G3QMG9 NIPSNAP1 PTHR21017:SF11 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 catabolic process#GO:0009056;macroautophagy#GO:0016236;cellular process#GO:0009987;autophagy#GO:0006914;mitophagy#GO:0000423;process utilizing autophagic mechanism#GO:0061919;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000040493.1|UniProtKB=A0A2I2ZRL4 A0A2I2ZRL4 PTHR10562:SF131 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 2-RELATED protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488 post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein sumoylation#GO:0016925;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 p53 pathway#P00059>Sumo-1 ligase#P04635 GORGO|Ensembl=ENSGGOG00000011468.3|UniProtKB=G3RR87 G3RR87 CRHR1 PTHR45620:SF2 PDF RECEPTOR-LIKE PROTEIN-RELATED CORTICOTROPIN-RELEASING HORMONE RECEPTOR 1 molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;binding#GO:0005488;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;hormone binding#GO:0042562 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 transmembrane signal receptor#PC00197 Cortocotropin releasing factor receptor signaling pathway#P04380>CRHR1#P04451 GORGO|Ensembl=ENSGGOG00000014336.3|UniProtKB=A0A2I2ZBR6 A0A2I2ZBR6 TARS1 PTHR11451:SF36 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE 1, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000011894.3|UniProtKB=G3SHI3 G3SHI3 NSD3 PTHR22884:SF473 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000011068.3|UniProtKB=G3R649 G3R649 LRRC66 PTHR24366:SF156 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT-CONTAINING PROTEIN 66 system process#GO:0003008;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;cognition#GO:0050890 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000005663.3|UniProtKB=G3QSB8 G3QSB8 GMDS PTHR43715:SF1 GDP-MANNOSE 4,6-DEHYDRATASE GDP-MANNOSE 4,6 DEHYDRATASE dehydratase#PC00091;lyase#PC00144 Mannose metabolism#P02752>GDP-Mannose 4,6-dehydratase#P03015 GORGO|Ensembl=ENSGGOG00000038289.1|UniProtKB=A0A2I2Y736 A0A2I2Y736 SMIM1 PTHR38503:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 1 SMALL INTEGRAL MEMBRANE PROTEIN 1 cellular process#GO:0009987;homeostatic process#GO:0042592;hemopoiesis#GO:0030097;cell development#GO:0048468;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;multicellular organismal process#GO:0032501;developmental process#GO:0032502;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;multicellular organismal-level homeostasis#GO:0048871;erythrocyte differentiation#GO:0030218;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000017193.3|UniProtKB=G3SE00 G3SE00 PTHR11304:SF18 EPHRIN EPHRIN-B2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;circulatory system development#GO:0072359;cell differentiation#GO:0030154;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;vasculature development#GO:0001944;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411 presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synaptic membrane#GO:0097060;cell junction#GO:0030054 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 Angiogenesis#P00005>Eph#P00239 GORGO|Ensembl=ENSGGOG00000024287.2|UniProtKB=G3S3M1 G3S3M1 IGFBPL1 PTHR14186:SF16 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-LIKE 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011697.3|UniProtKB=G3R7R1 G3R7R1 FUT7 PTHR11929:SF12 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE 7 fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000023723.2|UniProtKB=G3SBZ6 G3SBZ6 CLIC6 PTHR45476:SF1 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6 monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 establishment of localization#GO:0051234;localization#GO:0051179;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ion channel#PC00133 Nicotine pharmacodynamics pathway#P06587>CLIC6#P06611;Dopamine receptor mediated signaling pathway#P05912>CLIC6#P05968 GORGO|Ensembl=ENSGGOG00000027436.2|UniProtKB=G3SIU9 G3SIU9 PTHR12730:SF2 HSDA/SDA1-RELATED PROTEIN SDA1 nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;ribosomal large subunit export from nucleus#GO:0000055;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 GORGO|Ensembl=ENSGGOG00000037452.1|UniProtKB=A0A2I2YK72 A0A2I2YK72 TRGV9 PTHR19256:SF44 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 9 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000003214.3|UniProtKB=G3QL15 G3QL15 LOC101127921 PTHR26453:SF674 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2G3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002993.3|UniProtKB=G3QKG7 G3QKG7 VPS18 PTHR23323:SF29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosome organization#GO:0007032;organelle organization#GO:0006996;lysosome organization#GO:0007040;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;endomembrane system organization#GO:0010256;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;cellular localization#GO:0051641;localization#GO:0051179;vacuole organization#GO:0007033;cellular component organization#GO:0016043 vesicle tethering complex#GO:0099023;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000016851.3|UniProtKB=G3RXP2 G3RXP2 LOC109026842 PTHR23239:SF99 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA3-II structural molecule activity#GO:0005198 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000003756.3|UniProtKB=G3QMF3 G3QMF3 MID1 PTHR24099:SF23 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE MIDLINE-1 regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000011788.3|UniProtKB=G3R840 G3R840 PCNT PTHR44981:SF3 PERICENTRIN-LIKE PROTEIN, ISOFORM F PERICENTRIN protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278 GORGO|Ensembl=ENSGGOG00000007697.3|UniProtKB=G3QXI4 G3QXI4 CD52 PTHR15029:SF0 CAMPATH-1 ANTIGEN CAMPATH-1 ANTIGEN positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514 GORGO|Ensembl=ENSGGOG00000016075.3|UniProtKB=G3RJ10 G3RJ10 PAX1 PTHR45636:SF15 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;skeletal system development#GO:0001501;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000015740.3|UniProtKB=G3RI89 G3RI89 COL16A1 PTHR24023:SF372 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVI) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000037989.1|UniProtKB=A0A2I2Z5R5 A0A2I2Z5R5 ZNF143 PTHR24388:SF55 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 143 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004933.3|UniProtKB=G3QQH1 G3QQH1 ASCC2 PTHR21494:SF3 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 GORGO|Ensembl=ENSGGOG00000027414.2|UniProtKB=G3RY27 G3RY27 PTHR45893:SF2 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 6 negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000014677.3|UniProtKB=G3RFG1 G3RFG1 NDC1 PTHR13269:SF6 NUCLEOPORIN NDC1 NUCLEOPORIN NDC1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nuclear pore organization#GO:0006999;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000037991.1|UniProtKB=A0A2I2ZH43 A0A2I2ZH43 DEPP1 PTHR15426:SF6 PROTEIN DEPP1 PROTEIN DEPP1 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000027756.2|UniProtKB=A0A2I2Y1M9 A0A2I2Y1M9 MMP16 PTHR10201:SF26 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-16 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular component organization#GO:0016043;cellular process#GO:0009987;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;metabolic process#GO:0008152;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;skeletal system development#GO:0001501;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;system development#GO:0048731;external encapsulating structure organization#GO:0045229 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000009982.3|UniProtKB=G3R3D2 G3R3D2 WDR3 PTHR19853:SF0 WD REPEAT CONTAINING PROTEIN 3 WDR3 WD REPEAT-CONTAINING PROTEIN 3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000041615.1|UniProtKB=A0A2I2ZGR6 A0A2I2ZGR6 ZFP36L1 PTHR12547:SF53 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36L1 protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 metabolic process#GO:0008152;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000016782.3|UniProtKB=A0A2I2YC66 A0A2I2YC66 ACSF3 PTHR24096:SF435 LONG-CHAIN-FATTY-ACID--COA LIGASE MALONATE--COA LIGASE ACSF3, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000013053.3|UniProtKB=G3RB88 G3RB88 GPRIN2 PTHR15718:SF5 G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH C-TERMINAL DOMAIN-CONTAINING PROTEIN G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 2 nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000000537.3|UniProtKB=A0A2I2YQL0 A0A2I2YQL0 RNF220 PTHR13459:SF3 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 GORGO|Ensembl=ENSGGOG00000006158.3|UniProtKB=G3QTJ6 G3QTJ6 HRK PTHR15056:SF0 ACTIVATOR OF APOPTOSIS HARAKIRI ACTIVATOR OF APOPTOSIS HARAKIRI regulation of release of cytochrome c from mitochondria#GO:0090199;positive regulation of cellular component organization#GO:0051130;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;positive regulation of organelle organization#GO:0010638;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000040015.1|UniProtKB=A0A2I2Z757 A0A2I2Z757 PTHR11911:SF126 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED IMP DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000021982.2|UniProtKB=G3S5D6 G3S5D6 FAM43B PTHR11232:SF34 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN FAM43B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731;vasculature development#GO:0001944;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012426.3|UniProtKB=G3R9P0 G3R9P0 DOK4 PTHR21258:SF44 DOCKING PROTEIN RELATED DOCKING PROTEIN 4 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000044177.1|UniProtKB=A0A2I2YUU3 A0A2I2YUU3 PTHR24068:SF129 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBE2F ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000001914.3|UniProtKB=G3QHQ5 G3QHQ5 TTLL4 PTHR12241:SF162 TUBULIN POLYGLUTAMYLASE TUBULIN MONOGLUTAMYLASE TTLL4 binding#GO:0005488;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000000075.3|UniProtKB=G3QCX2 G3QCX2 C2H3orf38 PTHR21084:SF1 DENSE INCISORS SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 38 GORGO|Ensembl=ENSGGOG00000043931.1|UniProtKB=A0A2I2Y621 A0A2I2Y621 PTHR23267:SF313 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 5-2 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000011662.3|UniProtKB=G3R7N1 G3R7N1 CALHM3 PTHR32261:SF7 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 3 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000011336.3|UniProtKB=G3R6T5 G3R6T5 SAMHD1 PTHR11373:SF48 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;phosphorus metabolic process#GO:0006793;defense response to virus#GO:0051607;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;nucleotide metabolic process#GO:0009117;regulation of response to external stimulus#GO:0032101;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;regulation of immune system process#GO:0002682;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;regulation of response to biotic stimulus#GO:0002831;carbohydrate derivative catabolic process#GO:1901136;response to external biotic stimulus#GO:0043207;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;response to virus#GO:0009615;organophosphate catabolic process#GO:0046434;regulation of defense response#GO:0031347;purine nucleotide catabolic process#GO:0006195;regulation of immune response#GO:0050776;response to other organism#GO:0051707;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;regulation of innate immune response#GO:0045088;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stress#GO:0080134;nucleotide catabolic process#GO:0009166;regulation of response to stimulus#GO:0048583 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000009670.3|UniProtKB=G3R2J3 G3R2J3 A1CF PTHR21245:SF8 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN APOBEC1 COMPLEMENTATION FACTOR RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005898.3|UniProtKB=G3QSX6 G3QSX6 AQP5 PTHR19139:SF38 AQUAPORIN TRANSPORTER AQUAPORIN-5 channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;passive transmembrane transporter activity#GO:0022803 water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234;fluid transport#GO:0042044;transport#GO:0006810 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013452.3|UniProtKB=G3RC98 G3RC98 DFFB PTHR13067:SF2 CASPASE-ACTIVATED DNASE DNAATION FACTOR-RELATED PROTEIN 4 catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536 cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>CAD#P00618 GORGO|Ensembl=ENSGGOG00000005252.3|UniProtKB=A0A2I2ZU29 A0A2I2ZU29 CELSR2 PTHR24026:SF32 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 2 neuron projection development#GO:0031175;axon development#GO:0061564;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000024745.2|UniProtKB=G3R737 G3R737 PTHR24070:SF396 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN R-RAS2 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280 GORGO|Ensembl=ENSGGOG00000009079.3|UniProtKB=G3R122 G3R122 OR5D18 PTHR48018:SF121 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D18 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003703.3|UniProtKB=G3QMA8 G3QMA8 ZWILCH PTHR15995:SF1 PROTEIN ZWILCH HOMOLOG PROTEIN ZWILCH HOMOLOG negative regulation of cell cycle#GO:0045786;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;intracellular protein localization#GO:0008104;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;protein localization to kinetochore#GO:0034501;macromolecule localization#GO:0033036;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;localization#GO:0051179;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093 intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012156.3|UniProtKB=G3R8Y3 G3R8Y3 SULT2A1 PTHR11783:SF8 SULFOTRANSFERASE SULT SULFOTRANSFERASE 2A1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010788.3|UniProtKB=G3R5E4 G3R5E4 ARL1 PTHR11711:SF41 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1 carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 GORGO|Ensembl=ENSGGOG00000008330.3|UniProtKB=G3QZ45 G3QZ45 PHRF1 PTHR12618:SF20 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000038026.1|UniProtKB=A0A2I2ZWG6 A0A2I2ZWG6 PTHR23232:SF124 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 708 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000041390.1|UniProtKB=G3RXV4 G3RXV4 LOC101137977 PTHR10547:SF4 SEMENOGELIN/SEMINAL VESICLE SECRETORY PROTEIN SEMENOGELIN-1 cellular process#GO:0009987;developmental maturation#GO:0021700;male gamete generation#GO:0048232;sperm capacitation#GO:0048240;spermatogenesis#GO:0007283;developmental process#GO:0032502;cell maturation#GO:0048469;cellular developmental process#GO:0048869;developmental process involved in reproduction#GO:0003006;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000013683.3|UniProtKB=A0A2I2ZIX9 A0A2I2ZIX9 AP1S2 PTHR11753:SF19 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000011132.3|UniProtKB=G3R6A4 G3R6A4 STX11 PTHR19957:SF30 SYNTAXIN SYNTAXIN-11 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;exocytosis#GO:0006887;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle fusion#GO:0006906;export from cell#GO:0140352;cellular component organization#GO:0016043;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;protein transport#GO:0015031;secretion by cell#GO:0032940 intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;SNARE complex#GO:0031201;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 GORGO|Ensembl=ENSGGOG00000025030.2|UniProtKB=A0A2I2ZR84 A0A2I2ZR84 PSTPIP2 PTHR23065:SF9 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 2 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Gene=SCAND1|UniProtKB=A1YEW3 A1YEW3 SCAND1 PTHR45935:SF23 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000025908.2|UniProtKB=G3RQX8 G3RQX8 PPP1R2 PTHR12398:SF35 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE INHIBITOR 2-RELATED enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 phosphatase inhibitor#PC00183 GORGO|Ensembl=ENSGGOG00000000606.3|UniProtKB=G3QEA6 G3QEA6 ZNF791 PTHR24379:SF106 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 791 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000040269.1|UniProtKB=A0A2I2Z4G6 A0A2I2Z4G6 PTHR31577:SF2 DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 3-RELATED DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 3 histone H3K9me2/3 reader activity#GO:0062072;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;chromatin-protein adaptor activity#GO:0140463 chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell division#GO:0051301;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;embryo development#GO:0009790;chromatin organization#GO:0006325;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000039250.1|UniProtKB=G3RRY8 G3RRY8 PTHR11545:SF36 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of translation#GO:0017148;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000034969.2|UniProtKB=G3SKW7 G3SKW7 WBP2NL PTHR31606:SF2 WW DOMAIN BINDING PROTEIN 2, ISOFORM E POSTACROSOMAL SHEATH WW DOMAIN-BINDING PROTEIN transcription coregulator activity#GO:0003712;chromatin DNA binding#GO:0031490;transcription coactivator activity#GO:0003713;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000008489.3|UniProtKB=G3QZI7 G3QZI7 NFXL1 PTHR12360:SF1 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 NF-X1-TYPE ZINC FINGER PROTEIN NFXL1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000008756.3|UniProtKB=G3R085 G3R085 KAT6B PTHR10615:SF73 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT6B protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;binding#GO:0005488;acetyltransferase activity#GO:0016407;transcription regulator activity#GO:0140110;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;histone acetyltransferase activity#GO:0004402;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway#P00059>CBP#P04623 GORGO|Ensembl=ENSGGOG00000039312.1|UniProtKB=A0A2I2YI06 A0A2I2YI06 PTHR19433:SF119 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 35 response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to other organism#GO:0051707 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000013533.3|UniProtKB=G3SFU0 G3SFU0 DHX9 PTHR18934:SF119 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE A macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013361.3|UniProtKB=G3SER4 G3SER4 CTDSP1 PTHR12210:SF139 DULLARD PROTEIN PHOSPHATASE CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 1 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000009513.3|UniProtKB=G3R256 G3R256 PTHR12197:SF184 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD HISTONE-LYSINE N-METHYLTRANSFERASE SMYD1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279 heart development#GO:0007507;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000036420.1|UniProtKB=A0A2I2Y3G3 A0A2I2Y3G3 PTHR12391:SF6 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000024583.2|UniProtKB=G3SAW1 G3SAW1 PTHR12146:SF10 40S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN ES10 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000002018.3|UniProtKB=A0A2I2YJV1 A0A2I2YJV1 DAPK3 PTHR24347:SF372 SERINE/THREONINE-PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000016944.3|UniProtKB=G3RLA1 G3RLA1 PAXBP1 PTHR12214:SF2 GC-RICH SEQUENCE DNA-BINDING FACTOR PAX3- AND PAX7-BINDING PROTEIN 1 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000036395.1|UniProtKB=A0A2I2YQ40 A0A2I2YQ40 KCNA6 PTHR11537:SF104 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 6 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;metal ion transport#GO:0030001;action potential#GO:0001508 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000014048.3|UniProtKB=G3RSY8 G3RSY8 ROS1 PTHR24416:SF527 TYROSINE-PROTEIN KINASE RECEPTOR PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000515.3|UniProtKB=A0A2I2Z4M8 A0A2I2Z4M8 ATP6V1H PTHR10698:SF7 V-TYPE PROTON ATPASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT H cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801;organelle organization#GO:0006996;monoatomic cation transmembrane transport#GO:0098655;vesicle-mediated transport#GO:0016192;chemical homeostasis#GO:0048878;vesicle organization#GO:0016050;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular localization#GO:0051641;transmembrane transport#GO:0055085;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;developmental maturation#GO:0021700;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;synaptic vesicle cycle#GO:0099504;developmental process#GO:0032502;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;proton transmembrane transport#GO:1902600;homeostatic process#GO:0042592;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic cation transport#GO:0006812;localization#GO:0051179 transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020 primary active transporter#PC00068;ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000014809.3|UniProtKB=A0A2I2YQJ1 A0A2I2YQJ1 HYPK PTHR31184:SF2 HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER HUNTINGTIN-INTERACTING PROTEIN K negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of protein stability#GO:0031647;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008 GORGO|Ensembl=ENSGGOG00000011235.3|UniProtKB=G3R6J4 G3R6J4 FAM131B PTHR15736:SF9 PROTEIN FAM131B-RELATED PROTEIN FAM131B GORGO|Ensembl=ENSGGOG00000022611.2|UniProtKB=G3RWU8 G3RWU8 PTHR12786:SF4 SPLICING FACTOR SF3A-RELATED SPLICING FACTOR 3A SUBUNIT 3 binding#GO:0005488;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000038357.1|UniProtKB=G3SC51 G3SC51 LOC101137607 PTHR23262:SF170 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-9 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000006798.2|UniProtKB=A0A2I2Y926 A0A2I2Y926 PTHR46917:SF1 MORN REPEAT-CONTAINING PROTEIN 2 MORN REPEAT-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000014746.3|UniProtKB=G3RSI0 G3RSI0 MELK PTHR24346:SF122 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000004441.3|UniProtKB=G3QP70 G3QP70 SAP30L PTHR13286:SF5 SAP30 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30L transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 protein-containing complex#GO:0032991;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000005062.3|UniProtKB=A0A2I2ZNS9 A0A2I2ZNS9 PKM PTHR11817:SF101 PYRUVATE KINASE PYRUVATE KINASE PKM phosphotransferase activity, alcohol group as acceptor#GO:0016773;pyruvate kinase activity#GO:0004743;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;purine nucleoside triphosphate metabolic process#GO:0009144;response to insulin#GO:0032868;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside diphosphate metabolic process#GO:0009179;cellular response to insulin stimulus#GO:0032869;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;response to peptide hormone#GO:0043434;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;cellular response to chemical stimulus#GO:0070887;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;pyruvate metabolic process#GO:0006090;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;response to nitrogen compound#GO:1901698;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;cellular response to peptide hormone stimulus#GO:0071375;carbohydrate metabolic process#GO:0005975;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;cellular response to nitrogen compound#GO:1901699;nucleobase-containing compound metabolic process#GO:0006139;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;response to endogenous stimulus#GO:0009719;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;pyridine nucleotide catabolic process#GO:0019364;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;response to hormone#GO:0009725;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 Glycolysis#P00024>Pyruvate kinase#P00675;Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 GORGO|Ensembl=ENSGGOG00000000095.3|UniProtKB=G3QCZ2 G3QCZ2 ERFE PTHR24019:SF11 ADIPOLIN ERYTHROFERRONE signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000034928.2|UniProtKB=A0A2I2ZB43 A0A2I2ZB43 LOC101129066 PTHR47148:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000006197.3|UniProtKB=A0A2I2YF50 A0A2I2YF50 TRAF3IP3 PTHR15715:SF21 CENTROSOMAL PROTEIN OF 170 KDA TRAF3-INTERACTING JNK-ACTIVATING MODULATOR molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;negative regulation of signal transduction#GO:0009968;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;regulation of hippo signaling#GO:0035330;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;negative regulation of hippo signaling#GO:0035331;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;activation of innate immune response#GO:0002218;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;cellular response to stimulus#GO:0051716;antiviral innate immune response#GO:0140374;innate immune response-activating signaling pathway#GO:0002758;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;intracellular signal transduction#GO:0035556;response to virus#GO:0009615;cell communication#GO:0007154 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016703.3|UniProtKB=A0A2I2YG33 A0A2I2YG33 TTLL5 PTHR12241:SF164 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL5 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;tubulin binding#GO:0015631;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;spermatogenesis#GO:0007283;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000012942.3|UniProtKB=A0A2I2Z7V2 A0A2I2Z7V2 SYNPO2 PTHR24217:SF9 PUTATIVE-RELATED SYNAPTOPODIN-2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular developmental process#GO:0048869;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;regulation of cytoskeleton organization#GO:0051493;regulation of cell communication#GO:0010646;muscle cell development#GO:0055001;regulation of supramolecular fiber organization#GO:1902903;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;regulation of small GTPase mediated signal transduction#GO:0051056;cellular anatomical entity morphogenesis#GO:0032989;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of organelle organization#GO:0010638;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of Rho protein signal transduction#GO:0035023;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 actomyosin#GO:0042641;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;stress fiber#GO:0001725;I band#GO:0031674;membraneless organelle#GO:0043228;cell junction#GO:0030054;sarcomere#GO:0030017;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000010379.3|UniProtKB=G3R4C5 G3R4C5 SPTY2D1 PTHR22691:SF8 YEAST SPT2-RELATED PROTEIN SPT2 HOMOLOG histone binding#GO:0042393;nucleic acid binding#GO:0003676;binding#GO:0005488;protein binding#GO:0005515;DNA binding#GO:0003677 chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004682.3|UniProtKB=G3QPT4 G3QPT4 ONECUT1 PTHR14057:SF9 TRANSCRIPTION FACTOR ONECUT HEPATOCYTE NUCLEAR FACTOR 6 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008103.3|UniProtKB=A0A2I2Z0H9 A0A2I2Z0H9 HELLS PTHR47161:SF1 LYMPHOID-SPECIFIC HELICASE LYMPHOID-SPECIFIC HELICASE protein-macromolecule adaptor activity#GO:0030674;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;molecular adaptor activity#GO:0060090;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;chromatin-protein adaptor activity#GO:0140463 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;recombinational repair#GO:0000725;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;constitutive heterochromatin formation#GO:0140719;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;negative regulation of gene expression, epigenetic#GO:0045814;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;cellular response to stress#GO:0033554;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629 membraneless organelle#GO:0043228;heterochromatin#GO:0000792;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000012779.3|UniProtKB=G3RAJ9 G3RAJ9 CDK19 PTHR24056:SF570 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 19 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;protein kinase complex#GO:1902911;cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000011921.3|UniProtKB=A0A2I2YU21 A0A2I2YU21 PDGFA PTHR11633:SF3 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR SUBUNIT A protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;growth factor receptor binding#GO:0070851 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;positive regulation of signal transduction#GO:0009967;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of locomotion#GO:0040017;positive regulation of MAPK cascade#GO:0043410;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;tube development#GO:0035295;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;signaling#GO:0023052;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of ERK1 and ERK2 cascade#GO:0070372 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 PDGF signaling pathway#P00047>PDGF#P01170;Angiogenesis#P00005>PDGF#P00224 GORGO|Ensembl=ENSGGOG00000028339.2|UniProtKB=G3RVP7 G3RVP7 LYPLA1 PTHR10655:SF58 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 1 thiolester hydrolase activity#GO:0016790;carboxylic ester hydrolase activity#GO:0052689;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298;hydrolase activity#GO:0016787;palmitoyl hydrolase activity#GO:0098599;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;catalytic activity, acting on a protein#GO:0140096 regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of protein transport#GO:0051224;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;negative regulation of transport#GO:0051051;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of protein localization to membrane#GO:1905475;negative regulation of biological process#GO:0048519 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 phospholipase#PC00186;lipase#PC00143 GORGO|Ensembl=ENSGGOG00000005056.3|UniProtKB=G3QQS8 G3QQS8 PTHR26453:SF626 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007008.3|UniProtKB=G3QVS4 G3QVS4 LOC101125551 PTHR11266:SF39 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;regulation of membrane permeability#GO:0090559;negative regulation of response to stimulus#GO:0048585;negative regulation of programmed cell death#GO:0043069;negative regulation of cell communication#GO:0010648;regulation of biological quality#GO:0065008;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015432.3|UniProtKB=G3RHD7 G3RHD7 MVB12B PTHR31547:SF1 MULTIVESICULAR BODY SUBUNIT 12B MULTIVESICULAR BODY SUBUNIT 12B regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;ESCRT I complex#GO:0000813;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000003843.3|UniProtKB=G3QMN2 G3QMN2 RSBN1 PTHR13354:SF8 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE 9 demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000009014.3|UniProtKB=G3RS74 G3RS74 FLVCR2 PTHR10924:SF3 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED CHOLINE_ETHANOLAMINE TRANSPORTER FLVCR2 tetrapyrrole binding#GO:0046906;binding#GO:0005488;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;heme binding#GO:0020037 metal ion transport#GO:0030001;nitrogen compound transport#GO:0071705;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;iron ion transport#GO:0006826;transport#GO:0006810;transition metal ion transport#GO:0000041;iron coordination entity transport#GO:1901678 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000000056.3|UniProtKB=G3QCV7 G3QCV7 ALDH1A3 PTHR11699:SF209 ALDEHYDE DEHYDROGENASE-RELATED RETINALDEHYDE DEHYDROGENASE 3 oxidoreductase activity#GO:0016491;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;biological regulation#GO:0065007;biosynthetic process#GO:0009058;aldehyde catabolic process#GO:0046185;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;terpenoid biosynthetic process#GO:0016114;diterpenoid biosynthetic process#GO:0016102;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;monocarboxylic acid biosynthetic process#GO:0072330;regulation of hormone levels#GO:0010817;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;terpenoid metabolic process#GO:0006721;isoprenoid biosynthetic process#GO:0008299;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000013506.3|UniProtKB=G3RCE8 G3RCE8 SH3BP4 PTHR15603:SF3 SH3 DOMAIN-CONTAINING PROTEIN SH3 DOMAIN-BINDING PROTEIN 4 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;response to chemical#GO:0042221;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;response to acid chemical#GO:0001101;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039618.1|UniProtKB=G3SFL2 G3SFL2 PTHR15438:SF14 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER A1-RELATED GORGO|Ensembl=ENSGGOG00000024360.2|UniProtKB=A0A2I2YP58 A0A2I2YP58 PTHR11205:SF68 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 mRNA binding#GO:0003729;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000002222.3|UniProtKB=G3QIH8 G3QIH8 HOXA9 PTHR45970:SF3 AGAP004664-PA HOMEOBOX PROTEIN HOX-A9 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;skeletal system development#GO:0001501;embryo development#GO:0009790;anterior/posterior pattern specification#GO:0009952;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;skeletal system morphogenesis#GO:0048705;regulation of primary metabolic process#GO:0080090;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008210.3|UniProtKB=A0A2I2Z4D0 A0A2I2Z4D0 BNIPL PTHR12112:SF21 BNIP - RELATED BCL-2_ADENOVIRUS E1B 19 KDA-INTERACTING PROTEIN 2-LIKE PROTEIN programmed cell death#GO:0012501;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000004169.3|UniProtKB=G3QNH4 G3QNH4 ATXN1 PTHR13392:SF5 ATAXIN 1 ATAXIN-1 RNA binding#GO:0003723;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;nervous system development#GO:0007399;head development#GO:0060322;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000004736.3|UniProtKB=G3QPY1 G3QPY1 ARMC7 PTHR46263:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 7 ARMADILLO REPEAT-CONTAINING PROTEIN 7 GORGO|Ensembl=ENSGGOG00000003308.3|UniProtKB=G3QLA2 G3QLA2 TUBB6 PTHR11588:SF88 TUBULIN TUBULIN BETA-6 CHAIN nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166 microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 tubulin#PC00228;cytoskeletal protein#PC00085 Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780 GORGO|Ensembl=ENSGGOG00000006104.3|UniProtKB=G3QTF7 G3QTF7 JHY PTHR14726:SF1 JHY PROTEIN HOMOLOG JHY PROTEIN HOMOLOG animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;cilium organization#GO:0044782;system development#GO:0048731;axoneme assembly#GO:0035082;cilium assembly#GO:0060271;cellular component organization#GO:0016043;central nervous system development#GO:0007417;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;multicellular organismal process#GO:0032501;brain development#GO:0007420;cellular component assembly#GO:0022607;head development#GO:0060322;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010 GORGO|Ensembl=ENSGGOG00000024112.2|UniProtKB=A0A2I2Y4D8 A0A2I2Y4D8 PTHR10653:SF18 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of protein depolymerization#GO:1901879;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament organization#GO:0110053;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell periphery#GO:0071944;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000009405.3|UniProtKB=G3R1V8 G3R1V8 TMEM190 PTHR37868:SF1 TRANSMEMBRANE PROTEIN 190 TRANSMEMBRANE PROTEIN 190 developmental process#GO:0032502;cellular process#GO:0009987;hemopoiesis#GO:0030097;cell development#GO:0048468;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856 vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;acrosomal membrane#GO:0002080;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003315.3|UniProtKB=G3QLA7 G3QLA7 USH1G PTHR24161:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PRE-MRNA SPLICING REGULATOR USH1G sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877 9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;photoreceptor inner segment#GO:0001917;cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007711.3|UniProtKB=G3QXK9 G3QXK9 PTHR13723:SF151 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 17 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000000171.3|UniProtKB=G3QD61 G3QD61 CNOT10 PTHR12979:SF5 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000005704.3|UniProtKB=G3SHL1 G3SHL1 MAP3K21 PTHR23257:SF750 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 21 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000016639.3|UniProtKB=G3RKH0 G3RKH0 TYSND1 PTHR21004:SF0 SERINE PROTEASE-RELATED PEROXISOMAL LEADER PEPTIDE-PROCESSING PROTEASE catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of lipid catabolic process#GO:0050994;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;proteolysis#GO:0006508;regulation of lipid metabolic process#GO:0019216;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000000322.3|UniProtKB=G3QDJ4 G3QDJ4 PTHR12276:SF57 EPSIN/ENT-RELATED ENTH DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;clathrin binding#GO:0030276 localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987 endosome#GO:0005768;intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vesicle coat#GO:0030120 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000001313.3|UniProtKB=G3SDX1 G3SDX1 TEDC1 PTHR35076:SF1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 1 GORGO|Ensembl=ENSGGOG00000014278.3|UniProtKB=G3REE6 G3REE6 MAN1A2 PTHR11742:SF40 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IB hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011475.3|UniProtKB=G3RYY4 G3RYY4 ATP13A3 PTHR45630:SF12 CATION-TRANSPORTING ATPASE-RELATED POLYAMINE-TRANSPORTING ATPASE 13A3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;polyamine transmembrane transporter activity#GO:0015203 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;nitrogen compound transport#GO:0071705;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;transmembrane transport#GO:0055085;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000024478.2|UniProtKB=G3RZI3 G3RZI3 PIGF PTHR43157:SF79 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED GPI ETHANOLAMINE PHOSPHATE TRANSFERASE, STABILIZING SUBUNIT glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004058.3|UniProtKB=G3QN73 G3QN73 DACH1 PTHR12577:SF14 DACHSHUND DACHSHUND HOMOLOG 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000038810.1|UniProtKB=G3S0T1 G3S0T1 LOC101127726 PTHR23260:SF1 KERATIN ASSOCIATED PROTEIN 3-3-RELATED KERATIN-ASSOCIATED PROTEIN 3-3 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000013171.3|UniProtKB=G3RBJ4 G3RBJ4 EDEM2 PTHR45679:SF10 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 response to unfolded protein#GO:0006986;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of biological process#GO:0050789;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glycoprotein metabolic process#GO:0009100;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;carbohydrate derivative metabolic process#GO:1901135 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000000661.3|UniProtKB=A0A2I2Y9T1 A0A2I2Y9T1 PTHR46968:SF3 E3 UBIQUITIN-PROTEIN LIGASE RNF138 E3 UBIQUITIN-PROTEIN LIGASE RNF138 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;single-stranded DNA binding#GO:0003697;acyltransferase activity#GO:0016746;binding#GO:0005488;nucleic acid binding#GO:0003676;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;DNA binding#GO:0003677 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;double-strand break repair via single-strand annealing#GO:0045002;cellular response to stimulus#GO:0051716;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;site of double-strand break#GO:0035861;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000010994.3|UniProtKB=G3R5Y1 G3R5Y1 LOC101151556 PTHR24291:SF53 CYTOCHROME P450 FAMILY 4 ULTRA-LONG-CHAIN FATTY ACID OMEGA-HYDROXYLASE oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000015948.3|UniProtKB=G3RIG9 G3RIG9 PTHR48001:SF141 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015481.3|UniProtKB=A0A2I2YBK4 A0A2I2YBK4 VMA21 PTHR31792:SF3 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000026519.2|UniProtKB=G3RRM9 G3RRM9 PTHR15664:SF27 C20ORF30 PROTEIN TRANSMEMBRANE PROTEIN 230 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;organelle localization#GO:0051640;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;establishment of organelle localization#GO:0051656;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;synaptic vesicle transport#GO:0048489 cell junction#GO:0030054;secretory vesicle#GO:0099503;presynapse#GO:0098793;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000012492.3|UniProtKB=G3RX57 G3RX57 LRRC51 PTHR43836:SF1 CATECHOL O-METHYLTRANSFERASE 1-RELATED TRANSMEMBRANE O-METHYLTRANSFERASE O-methyltransferase activity#GO:0008171;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056;amine catabolic process#GO:0009310;metabolic process#GO:0008152;catecholamine metabolic process#GO:0006584 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000038597.1|UniProtKB=A0A2I2YIJ7 A0A2I2YIJ7 HILPDA PTHR16886:SF0 HYPOXIA-INDUCIBLE PROTEIN 2 HYPOXIA-INDUCIBLE LIPID DROPLET-ASSOCIATED PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000007972.3|UniProtKB=G3QY83 G3QY83 PKD1L3 PTHR10877:SF136 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-1-LIKE PROTEIN 3 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 detection of mechanical stimulus#GO:0050982;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;response to mechanical stimulus#GO:0009612;response to stimulus#GO:0050896;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000006034.3|UniProtKB=G3QT91 G3QT91 CCNJ PTHR10177:SF62 CYCLINS CYCLIN-J cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000008671.3|UniProtKB=G3R004 G3R004 SLC15A3 PTHR11654:SF95 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;dipeptide transmembrane transporter activity#GO:0071916;oligopeptide transmembrane transporter activity#GO:0035673 import across plasma membrane#GO:0098739;oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;oligopeptide transport#GO:0006857;localization#GO:0051179;dipeptide transport#GO:0042938;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810 vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004479.3|UniProtKB=G3QPA2 G3QPA2 GNRH1 PTHR10522:SF0 GONADOLIBERIN PROGONADOLIBERIN-1 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179;intercellular signal molecule#PC00207 Gonadotropin-releasing hormone receptor pathway#P06664>GnRH#P06704 GORGO|Gene=COX4I1|UniProtKB=O46578 O46578 COX4I1 PTHR10707:SF12 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 1, MITOCHONDRIAL aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000014934.3|UniProtKB=A0A2I2ZY34 A0A2I2ZY34 C15H14orf180 PTHR36868:SF1 NUTRITIONALLY-REGULATED ADIPOSE AND CARDIAC ENRICHED PROTEIN HOMOLOG NUTRITIONALLY-REGULATED ADIPOSE AND CARDIAC ENRICHED PROTEIN HOMOLOG GORGO|Ensembl=ENSGGOG00000023135.2|UniProtKB=G3S8S1 G3S8S1 TOP3B PTHR11390:SF20 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-BETA-1 isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000040072.1|UniProtKB=A0A2I2YFF5 A0A2I2YFF5 ANXA2R PTHR38820:SF1 ANNEXIN-2 RECEPTOR ANNEXIN-2 RECEPTOR transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008500.3|UniProtKB=G3QZI9 G3QZI9 POLR3K PTHR11239:SF12 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10 nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000028241.2|UniProtKB=A0A2I2ZDE8 A0A2I2ZDE8 PTHR45809:SF6 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN DOMAIN-CONTAINING PROTEIN cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;growth factor receptor binding#GO:0070851;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;protein folding#GO:0006457;circulatory system development#GO:0072359;metabolic process#GO:0008152;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;protein maturation#GO:0051604;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;biosynthetic process#GO:0009058;tube development#GO:0035295;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000013404.3|UniProtKB=G3RC53 G3RC53 COMMD3 PTHR31159:SF1 COMM DOMAIN-CONTAINING PROTEIN 3 COMM DOMAIN-CONTAINING PROTEIN 3 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000036408.1|UniProtKB=A0A2I2ZA77 A0A2I2ZA77 PTHR23222:SF23 PROHIBITIN PROHIBITIN mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000010698.3|UniProtKB=G3S7S7 G3S7S7 MBD4 PTHR15074:SF7 METHYL-CPG-BINDING PROTEIN METHYL-CPG-BINDING DOMAIN PROTEIN 4 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000001400.3|UniProtKB=G3QGC7 G3QGC7 PTHR13999:SF4 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 3 response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;response to virus#GO:0009615;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to type II interferon#GO:0034341;cellular process#GO:0009987;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000027855.2|UniProtKB=G3RYB7 G3RYB7 KCTD8 PTHR14499:SF68 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD8 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;animal gross anatomical part developmental process#GO:0160108;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of biological process#GO:0050789 presynaptic active zone membrane#GO:0048787;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic membrane#GO:0045211;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cell junction#GO:0030054;presynaptic active zone#GO:0048786 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007056.3|UniProtKB=G3QVW4 G3QVW4 GPR132 PTHR24234:SF7 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G PROTEIN-COUPLED RECEPTOR 132-RELATED biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;mitotic cell cycle process#GO:1903047;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;G1/S transition of mitotic cell cycle#GO:0000082;regulation of cell cycle#GO:0051726;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic cell cycle phase transition#GO:0044772 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000036424.1|UniProtKB=A0A2I2Y4D9 A0A2I2Y4D9 SRPK3 PTHR47634:SF20 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SRSF PROTEIN KINASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;cell communication#GO:0007154;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;mRNA metabolic process#GO:0016071;signaling#GO:0023052;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000023061.2|UniProtKB=G3SAP9 G3SAP9 PTHR11489:SF17 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2-RELATED structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;translation#GO:0006412;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000040122.1|UniProtKB=A0A2I2YDM2 A0A2I2YDM2 PTHR10652:SF18 ADENYLYL CYCLASE-ASSOCIATED PROTEIN C-CAP_COFACTOR C-LIKE DOMAIN-CONTAINING PROTEIN actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515 actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;developmental process#GO:0032502;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;cell morphogenesis#GO:0000902;actin cytoskeleton organization#GO:0030036;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000008170.3|UniProtKB=G3QYP7 G3QYP7 CBLIF PTHR10559:SF15 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR COBALAMIN BINDING INTRINSIC FACTOR tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;binding#GO:0005488 localization#GO:0051179;vitamin transport#GO:0051180;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;transport#GO:0006810 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000042890.1|UniProtKB=A0A2I2YLM9 A0A2I2YLM9 SOCS4 PTHR10155:SF21 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 4 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;signaling#GO:0023052;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 GORGO|Ensembl=ENSGGOG00000004804.3|UniProtKB=G3QQ53 G3QQ53 PTHR47740:SF1 LCK-INTERACTING TRANSMEMBRANE ADAPTER 1, LIME1 LCK-INTERACTING TRANSMEMBRANE ADAPTER 1 protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;immune system process#GO:0002376;regulation of immune response#GO:0050776;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007967.3|UniProtKB=G3QY69 G3QY69 DMPK PTHR22988:SF79 MYOTONIC DYSTROPHY S/T KINASE-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000025844.2|UniProtKB=A0A2I2Y4F9 A0A2I2Y4F9 HNRNPH1 PTHR13976:SF60 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000002223.3|UniProtKB=G3QII0 G3QII0 RORC PTHR45805:SF1 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-GAMMA sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;sterol binding#GO:0032934;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;lipid binding#GO:0008289;sequence-specific double-stranded DNA binding#GO:1990837;steroid binding#GO:0005496;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 Hypoxia response via HIF activation#P00030>TOR#P00817 GORGO|Ensembl=ENSGGOG00000026879.2|UniProtKB=G3S6H1 G3S6H1 HSPA5 PTHR19375:SF380 HEAT SHOCK PROTEIN 70KDA ENDOPLASMIC RETICULUM CHAPERONE BIP ribonucleoside triphosphate phosphatase activity#GO:0017111;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;gene expression#GO:0010467;protein maturation#GO:0051604;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;protein folding#GO:0006457;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;protein refolding#GO:0042026;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;protein metabolic process#GO:0019538;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 GORGO|Ensembl=ENSGGOG00000004567.3|UniProtKB=G3SGI0 G3SGI0 LOC101142172 PTHR48001:SF51 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1L1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026763.2|UniProtKB=G3S962 G3S962 S100A16 PTHR11639:SF76 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A16 cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;perinuclear region of cytoplasm#GO:0048471;extracellular region#GO:0005576 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000025893.2|UniProtKB=A0A2I2ZTH3 A0A2I2ZTH3 ADH4 PTHR43880:SF14 ALCOHOL DEHYDROGENASE ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH4 transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;zinc ion binding#GO:0008270;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;detoxification#GO:0098754;response to chemical#GO:0042221;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;small molecule catabolic process#GO:0044282;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;cellular detoxification of aldehyde#GO:0110095 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 GORGO|Gene=TAS2R10|UniProtKB=Q645Z4 Q645Z4 TAS2R10 PTHR11394:SF63 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 10 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010409.3|UniProtKB=G3R4F1 G3R4F1 VSTM5 PTHR12080:SF93 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;regulation of multicellular organismal process#GO:0051239;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;regulation of biological quality#GO:0065008;immune system process#GO:0002376;positive regulation of cellular component organization#GO:0051130;regulation of synapse organization#GO:0050807;response to stimulus#GO:0050896;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;positive regulation of synapse assembly#GO:0051965;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of developmental process#GO:0051094;regulation of synapse assembly#GO:0051963;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;filopodium assembly#GO:0046847;cell communication#GO:0007154;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;regulation of cell junction assembly#GO:1901888;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;cellular response to stimulus#GO:0051716 neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000012645.3|UniProtKB=G3RA82 G3RA82 E2F7 PTHR12081:SF25 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F7 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000012281.3|UniProtKB=G3R9A8 G3R9A8 TCERG1L PTHR15377:SF5 TRANSCRIPTION ELONGATION REGULATOR 1 TRANSCRIPTION ELONGATION REGULATOR 1-LIKE PROTEIN protein binding#GO:0005515;RNA polymerase binding#GO:0070063;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;transcription coregulator activity#GO:0003712;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000000704.3|UniProtKB=A0A2I2ZF08 A0A2I2ZF08 NHS PTHR23039:SF5 NANCE-HORAN SYNDROME PROTEIN ACTIN REMODELING REGULATOR NHS sensory system development#GO:0048880;multicellular organismal process#GO:0032501;visual system development#GO:0150063;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;eye development#GO:0001654;system development#GO:0048731 GORGO|Ensembl=ENSGGOG00000004938.3|UniProtKB=G3QQH3 G3QQH3 CALB1 PTHR19972:SF14 CALBINDIN CALBINDIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;neuron projection terminus#GO:0044306;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;axon#GO:0030424;dendrite#GO:0030425;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;nucleus#GO:0005634;presynapse#GO:0098793;neuron projection#GO:0043005;cytosol#GO:0005829;axon terminus#GO:0043679;cell junction#GO:0030054 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000001935.3|UniProtKB=G3QHR9 G3QHR9 KEAP1 PTHR24412:SF162 KELCH PROTEIN KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022588.2|UniProtKB=A0A2I2YGD4 A0A2I2YGD4 PTHR12642:SF1 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000022475.2|UniProtKB=G3RS61 G3RS61 CBLB PTHR23007:SF3 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL-B transferase activity#GO:0016740;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;receptor tyrosine kinase binding#GO:0030971;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;ubiquitin-like protein transferase activity#GO:0019787 negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane raft#GO:0045121;membrane#GO:0016020;cell periphery#GO:0071944;membrane microdomain#GO:0098857 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 GORGO|Ensembl=ENSGGOG00000040743.1|UniProtKB=A0A2I2ZXY3 A0A2I2ZXY3 PTHR15896:SF11 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000003227.3|UniProtKB=G3QL33 G3QL33 SMO PTHR11309:SF35 FRIZZLED PROTEIN SMOOTHENED signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;central nervous system development#GO:0007417;response to stimulus#GO:0050896;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;pattern specification process#GO:0007389;smoothened signaling pathway#GO:0007224;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070 cilium#GO:0005929;dendritic tree#GO:0097447;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transmembrane signal receptor#PC00197 Hedgehog signaling pathway#P00025>Smoothened#P00685 GORGO|Ensembl=ENSGGOG00000007274.3|UniProtKB=G3QWF9 G3QWF9 CHST8 PTHR12137:SF7 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 8 catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009623.3|UniProtKB=G3S3B7 G3S3B7 LOC101129526 PTHR24223:SF339 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 6 xenobiotic transmembrane transporter activity#GO:0042910;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000016902.3|UniProtKB=G3RL50 G3RL50 ZNF716 PTHR23226:SF234 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 716 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015557.3|UniProtKB=G3RHQ8 G3RHQ8 SCAF4 PTHR23140:SF3 RNA PROCESSING PROTEIN LD23810P SR-RELATED AND CTD-ASSOCIATED FACTOR 4 protein binding#GO:0005515;RNA binding#GO:0003723;RNA polymerase II complex binding#GO:0000993;binding#GO:0005488;nucleic acid binding#GO:0003676;enzyme binding#GO:0019899;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase binding#GO:0070063 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000007898.3|UniProtKB=G3QY03 G3QY03 GNG4 PTHR13809:SF21 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-4 molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796 heterotrimeric G-protein#PC00117 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;GABA-B receptor II signaling#P05731>Ggamma#P05754;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 GORGO|Ensembl=ENSGGOG00000008412.3|UniProtKB=G3QZB2 G3QZB2 SPINK1 PTHR21312:SF27 SERINE PROTEASE INHIBITOR SERINE PROTEASE INHIBITOR KAZAL-TYPE 1 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000003493.3|UniProtKB=A0A2I2ZVZ4 A0A2I2ZVZ4 ATG7 PTHR10953:SF3 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7 catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;Atg12 activating enzyme activity#GO:0019778;transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;cellular component assembly#GO:0022607;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;process utilizing autophagic mechanism#GO:0061919;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular component organization#GO:0016043;protein modification by small protein conjugation#GO:0032446;macromolecule metabolic process#GO:0043170;mitophagy#GO:0000423;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;post-translational protein modification#GO:0043687;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;vacuole organization#GO:0007033;organelle assembly#GO:0070925;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;phagophore assembly site#GO:0000407 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 GORGO|Ensembl=ENSGGOG00000002819.3|UniProtKB=G3QK16 G3QK16 NEK10 PTHR43671:SF92 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK10 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of cell cycle G2/M phase transition#GO:1902749;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;protein-containing complex#GO:0032991 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003137.3|UniProtKB=G3QKV1 G3QKV1 RASGEF1C PTHR23113:SF186 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1C enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000012771.3|UniProtKB=G3RAI4 G3RAI4 CACNG1 PTHR15025:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062 calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;sarcolemma#GO:0042383;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 transporter#PC00227;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000041028.1|UniProtKB=A0A2I2YCA9 A0A2I2YCA9 PTHR23359:SF225 NUCLEOTIDE KINASE SUBFAMILY NOT NAMED phosphotransferase activity, phosphate group as acceptor#GO:0016776;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740 ADP metabolic process#GO:0046031;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;organophosphate biosynthetic process#GO:0090407;nucleoside diphosphate metabolic process#GO:0009132;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 kinase#PC00137;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000013497.3|UniProtKB=G3RCD6 G3RCD6 EXOSC7 PTHR11097:SF8 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP42 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000012762.3|UniProtKB=G3RAH9 G3RAH9 PTHR45819:SF8 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 11 ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;pyrophosphatase activity#GO:0016462;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000041724.1|UniProtKB=A0A2I2YLA2 A0A2I2YLA2 PTHR15566:SF7 POM121-LIKE UPF0607 PROTEIN ENSP00000381514-RELATED GORGO|Ensembl=ENSGGOG00000014714.3|UniProtKB=G3RFI8 G3RFI8 SLURP2 PTHR16983:SF14 UPAR/LY6 DOMAIN-CONTAINING PROTEIN SECRETED LY-6_UPAR DOMAIN-CONTAINING PROTEIN 2 molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;neurotransmitter receptor regulator activity#GO:0099602;protein binding#GO:0005515;binding#GO:0005488;acetylcholine receptor inhibitor activity#GO:0030550;signaling receptor binding#GO:0005102;acetylcholine receptor regulator activity#GO:0030548 response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000027383.2|UniProtKB=G3S2M2 G3S2M2 MYO1F PTHR13140:SF663 MYOSIN UNCONVENTIONAL MYOSIN-IF microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 actin filament-based process#GO:0030029;transport#GO:0006810;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897 intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000007933.3|UniProtKB=A0A2I2Y2K6 A0A2I2Y2K6 MYO19 PTHR13140:SF289 MYOSIN UNCONVENTIONAL MYOSIN-XIX cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000001441.3|UniProtKB=A0A2I2Z3R1 A0A2I2Z3R1 LOC101129546 PTHR26453:SF254 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000614.3|UniProtKB=G3QEB4 G3QEB4 CTNNBL1 PTHR14978:SF4 BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN BETA-CATENIN-LIKE PROTEIN 1 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 GORGO|Ensembl=ENSGGOG00000027068.2|UniProtKB=A0A2I2Y1R3 A0A2I2Y1R3 TLE7 PTHR10814:SF33 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 7 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of cell communication#GO:0010648;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of canonical Wnt signaling pathway#GO:0060828 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000000658.3|UniProtKB=G3QEF4 G3QEF4 ZNF649 PTHR24404:SF34 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 649 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000004415.3|UniProtKB=G3QP47 G3QP47 EXTL2 PTHR47844:SF1 SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED EXOSTOSIN-LIKE 2 GORGO|Ensembl=ENSGGOG00000005907.3|UniProtKB=G3SHS4 G3SHS4 ARHGEF2 PTHR13944:SF20 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;actin filament organization#GO:0007015;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;actin filament-based process#GO:0030029;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;actin cytoskeleton organization#GO:0030036 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;leading edge membrane#GO:0031256;intracellular anatomical structure#GO:0005622;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;ruffle membrane#GO:0032587;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;ruffle#GO:0001726 GORGO|Ensembl=ENSGGOG00000002574.3|UniProtKB=A0A2I2Y2J1 A0A2I2Y2J1 RFC5 PTHR11669:SF9 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 5 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 chromosome#GO:0005694;nucleus#GO:0005634;replication fork#GO:0005657;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 GORGO|Ensembl=ENSGGOG00000014399.3|UniProtKB=G3REP8 G3REP8 ZFP36 PTHR12547:SF58 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36 RNA binding#GO:0003723;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182;protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015552.3|UniProtKB=G3RHP3 G3RHP3 LOC101126391 PTHR13813:SF3 GLYCOPHORIN GLYCOPHORIN-A plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000024682.2|UniProtKB=G3RXL6 G3RXL6 DACT2 PTHR15919:SF13 DAPPER-RELATED DAPPER HOMOLOG 2 regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000013857.3|UniProtKB=G3RDD0 G3RDD0 EDC4 PTHR15598:SF5 ENHANCER OF MRNA-DECAPPING PROTEIN 4 ENHANCER OF MRNA-DECAPPING PROTEIN 4 molecular condensate scaffold activity#GO:0140693;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 RNA catabolic process#GO:0006401;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 mRNA capping factor#PC00145 GORGO|Ensembl=ENSGGOG00000005043.3|UniProtKB=A0A2I2YKC4 A0A2I2YKC4 C9H11orf98 PTHR14987:SF1 PROTEIN LBH-RELATED LBH DOMAIN-CONTAINING PROTEIN 1 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014546.3|UniProtKB=G3RF31 G3RF31 SLC45A1 PTHR19432:SF6 SUGAR TRANSPORTER PROTON-ASSOCIATED SUGAR TRANSPORTER A solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000000867.3|UniProtKB=G3QEZ5 G3QEZ5 PTHR21564:SF2 BRAKELESS PROTEIN ZINC FINGER PROTEIN 609 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000024900.2|UniProtKB=G3SHG8 G3SHG8 ANHX PTHR10390:SF34 HOMEOBOX PROTEIN SIX ANOMALOUS HOMEOBOX PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000014244.3|UniProtKB=G3REB1 G3REB1 ACOT13 PTHR21660:SF1 THIOESTERASE SUPERFAMILY MEMBER-RELATED ACYL-COENZYME A THIOESTERASE 13 catalytic activity#GO:0003824;acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215;fatty acyl-CoA hydrolase activity#GO:0047617;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002510.3|UniProtKB=G3QJ90 G3QJ90 DIXDC1 PTHR10878:SF22 SEGMENT POLARITY PROTEIN DISHEVELLED DIXIN cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009482.3|UniProtKB=G3R232 G3R232 ANKRD13A PTHR12447:SF4 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879 endomembrane system#GO:0012505;late endosome#GO:0005770;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011706.3|UniProtKB=G3R7R6 G3R7R6 ZBED1 PTHR46169:SF2 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A E3 SUMO-PROTEIN LIGASE ZBED1 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000016358.3|UniProtKB=A7X8B7 A7X8B7 PGR PTHR48092:SF6 KNIRPS-RELATED PROTEIN-RELATED PROGESTERONE RECEPTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to steroid hormone stimulus#GO:0071383;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;intracellular receptor signaling pathway#GO:0030522;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;response to steroid hormone#GO:0048545;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>PR#P06708 GORGO|Ensembl=ENSGGOG00000024624.2|UniProtKB=G3S3L3 G3S3L3 PTHR11736:SF86 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN C3 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010600.3|UniProtKB=G3R4W5 G3R4W5 QRFP PTHR36476:SF1 OREXIGENIC NEUROPEPTIDE QRFP OREXIGENIC NEUROPEPTIDE QRFP molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;neuropeptide hormone activity#GO:0005184;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signaling#GO:0023052;regulation of multicellular organismal process#GO:0051239 GORGO|Ensembl=ENSGGOG00000025696.2|UniProtKB=G3SAE1 G3SAE1 LURAP1 PTHR33767:SF2 LEUCINE RICH ADAPTOR PROTEIN 1-LIKE LEUCINE RICH ADAPTOR PROTEIN 1 regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;positive regulation of signal transduction#GO:0009967;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 GORGO|Ensembl=ENSGGOG00000002626.3|UniProtKB=G3SC49 G3SC49 ADGRG6 PTHR12011:SF290 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G6 extracellular matrix binding#GO:0050840;protein binding#GO:0005515;molecular transducer activity#GO:0060089;laminin binding#GO:0043236;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930 G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;circulatory system development#GO:0072359;response to stimulus#GO:0050896;signaling#GO:0023052;cell development#GO:0048468;peripheral nervous system development#GO:0007422;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;animal organ development#GO:0048513;gliogenesis#GO:0042063;anatomical structure formation involved in morphogenesis#GO:0048646;myelination#GO:0042552;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;heart development#GO:0007507;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;heart morphogenesis#GO:0003007;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004839.3|UniProtKB=G3QQ78 G3QQ78 PTHR15478:SF11 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY LIKE DOMAIN FAMILY A MEMBER 3 positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;intracellular signal transduction#GO:0035556;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;signal transduction by p53 class mediator#GO:0072331;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;intrinsic apoptotic signaling pathway#GO:0097193;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000027549.2|UniProtKB=G3SJ00 G3SJ00 TEX15 PTHR22380:SF1 TESTIS-EXPRESSED PROTEIN 15 TESTIS-EXPRESSED PROTEIN 15 chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;male meiotic nuclear division#GO:0007140;homologous chromosome pairing at meiosis#GO:0007129;cellular component assembly#GO:0022607;synaptonemal complex assembly#GO:0007130;regulation of DNA recombination#GO:0000018;nuclear division#GO:0000280;regulation of cellular response to stress#GO:0080135;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;regulation of double-strand break repair via homologous recombination#GO:0010569;gamete generation#GO:0007276;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of response to stress#GO:0080134;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;male gamete generation#GO:0048232;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;regulation of double-strand break repair#GO:2000779;multicellular organismal reproductive process#GO:0048609;organelle fission#GO:0048285;cell cycle#GO:0007049;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000003094.3|UniProtKB=G3QKR3 G3QKR3 ALG5 PTHR10859:SF91 GLYCOSYL TRANSFERASE DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000004386.3|UniProtKB=G3QP16 G3QP16 SRSF1 PTHR23147:SF44 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 1 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;nuclear speck#GO:0016607;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000013036.3|UniProtKB=G3RB78 G3RB78 FAAP20 PTHR37862:SF1 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 20 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 20 binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;modification-dependent protein binding#GO:0140030;protein binding#GO:0005515 response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000012009.3|UniProtKB=G3R8L2 G3R8L2 WDTC1 PTHR15574:SF40 WD REPEAT DOMAIN-CONTAINING FAMILY WD AND TETRATRICOPEPTIDE REPEATS PROTEIN 1 negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of lipid biosynthetic process#GO:0046890;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;negative regulation of biosynthetic process#GO:0009890;regulation of lipid metabolic process#GO:0019216;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012934.3|UniProtKB=G3SCD3 G3SCD3 CLCN6 PTHR11689:SF158 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 6 voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 chloride transport#GO:0006821;monoatomic anion transport#GO:0006820;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000011904.3|UniProtKB=G3SG18 G3SG18 TNFRSF1A PTHR46861:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A protein binding#GO:0005515;molecular transducer activity#GO:0060089;tumor necrosis factor binding#GO:0043120;death receptor activity#GO:0005035;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 inflammatory response#GO:0006954;response to stress#GO:0006950;defense response#GO:0006952;response to stimulus#GO:0050896 signaling receptor complex#GO:0043235;membrane microdomain#GO:0098857;membrane raft#GO:0045121;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TNFR1#P00288 GORGO|Ensembl=ENSGGOG00000016750.3|UniProtKB=G3SDN5 G3SDN5 YME1L1 PTHR23076:SF144 METALLOPROTEASE M41 FTSH ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1 ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule catabolic process#GO:0009057;mitochondrion organization#GO:0007005;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000005699.3|UniProtKB=G3QSF2 G3QSF2 MYPN PTHR13817:SF67 TITIN MYOPALLADIN structural molecule activity#GO:0005198 actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 contractile muscle fiber#GO:0043292;A band#GO:0031672;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;M band#GO:0031430;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000009308.3|UniProtKB=G3R1M0 G3R1M0 CACNB2 PTHR11824:SF9 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2 anterograde trans-synaptic signaling#GO:0098916;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 voltage-gated ion channel#PC00241 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438 GORGO|Ensembl=ENSGGOG00000000600.3|UniProtKB=G3QE99 G3QE99 PRRX2 PTHR46385:SF3 PAIRED MESODERM HOMEOBOX PROTEIN 1-RELATED PAIRED MESODERM HOMEOBOX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 Gonadotropin-releasing hormone receptor pathway#P06664>Prx2#P06731 GORGO|Ensembl=ENSGGOG00000009603.3|UniProtKB=G3R2D4 G3R2D4 ACAD9 PTHR43884:SF9 ACYL-COA DEHYDROGENASE COMPLEX I ASSEMBLY FACTOR ACAD9, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007959.4|UniProtKB=G3QY50 G3QY50 HAUS7 PTHR14352:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle process#GO:0022402 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;HAUS complex#GO:0070652;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000026866.2|UniProtKB=G3SK50 G3SK50 PTHR15578:SF0 CHROMOSOME 8 C22ORF31 HOMOLOG CHROMOSOME 22 OPEN READING FRAME 31 GORGO|Ensembl=ENSGGOG00000013172.3|UniProtKB=G3RBJ2 G3RBJ2 CSTL1 PTHR47887:SF1 CYSTATIN-LIKE 1 CYSTATIN-LIKE 1 peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538 GORGO|Ensembl=ENSGGOG00000025393.2|UniProtKB=G3SB61 G3SB61 PTHR46734:SF2 TELOMERIC REPEAT-BINDING FACTOR 1 TERF1 TELOMERIC REPEAT-BINDING FACTOR transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;telomerase activity#GO:0003720;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;RNA-directed DNA polymerase activity#GO:0003964;double-stranded DNA binding#GO:0003690 nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;telomere maintenance via telomerase#GO:0007004;telomere maintenance via telomere lengthening#GO:0010833;nucleic acid biosynthetic process#GO:0141187;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;RNA-templated DNA biosynthetic process#GO:0006278;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;regulation of telomere maintenance#GO:0032204;telomere maintenance#GO:0000723;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of chromosome organization#GO:2001251;telomere organization#GO:0032200;primary metabolic process#GO:0044238;negative regulation of organelle organization#GO:0010639;nucleic acid metabolic process#GO:0090304;negative regulation of cellular component organization#GO:0051129;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 chromosome#GO:0005694;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear telomere cap complex#GO:0000783;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000005153.3|UniProtKB=G3QR16 G3QR16 TNFRSF12A PTHR32037:SF2 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 12A TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 12A transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016136.3|UniProtKB=G3RJ63 G3RJ63 GABRQ PTHR18945:SF579 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT THETA ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;channel activity#GO:0015267;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;trans-synaptic signaling#GO:0099537 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;GABA-ergic synapse#GO:0098982;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000016993.3|UniProtKB=G3RLE4 G3RLE4 EPHX2 PTHR43329:SF165 EPOXIDE HYDROLASE BIFUNCTIONAL EPOXIDE HYDROLASE 2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 lipid modification#GO:0030258;dephosphorylation#GO:0016311;cholesterol homeostasis#GO:0042632;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000037575.1|UniProtKB=A0A2I2YP93 A0A2I2YP93 PTHR23267:SF393 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-12 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000001377.3|UniProtKB=G3QGA8 G3QGA8 USP39 PTHR21646:SF16 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 39 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;regulation of protein stability#GO:0031647;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000003318.4|UniProtKB=G3QLB4 G3QLB4 DOK6 PTHR21258:SF43 DOCKING PROTEIN RELATED DOCKING PROTEIN 6 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014540.3|UniProtKB=A0A2I2YY49 A0A2I2YY49 NUB1 PTHR12948:SF3 NEDD8 ULTIMATE BUSTER-1 BS4 PROTEIN NEDD8 ULTIMATE BUSTER 1 regulation of catabolic process#GO:0009894;regulation of protein catabolic process#GO:0042176;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000012260.3|UniProtKB=G3R996 G3R996 MST1R PTHR24416:SF564 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE-STIMULATING PROTEIN RECEPTOR catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;cell motility#GO:0048870;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;localization#GO:0051179;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell migration#GO:0016477;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;import into cell#GO:0098657;phagocytosis#GO:0006909;developmental process#GO:0032502;transport#GO:0006810;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043469.1|UniProtKB=A0A2I2ZH19 A0A2I2ZH19 LSM5 PTHR20971:SF0 U6 SNRNA-ASSOCIATED PROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;Lsm2-8 complex#GO:0120115;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;U6 snRNP#GO:0005688;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000039455.1|UniProtKB=A0A2I2YE38 A0A2I2YE38 FGF2 PTHR11486:SF83 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 2 molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 growth factor#PC00112;intercellular signal molecule#PC00207 Angiogenesis#P00005>FGF#P00213;FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000000422.3|UniProtKB=G3QDT9 G3QDT9 ZNF764 PTHR24381:SF299 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 764 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008326.3|UniProtKB=G3QZ37 G3QZ37 GTF3C4 PTHR15496:SF2 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000005050.3|UniProtKB=A0A2I2ZSG6 A0A2I2ZSG6 DERA PTHR10889:SF3 DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOXYRIBOSE-PHOSPHATE ALDOLASE lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleobase-containing small molecule catabolic process#GO:0034656;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside catabolic process#GO:0009164;metabolic process#GO:0008152 aldolase#PC00044;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000003204.3|UniProtKB=G3QL09 G3QL09 FANCG PTHR15254:SF2 FANCONI ANEMIA GROUP G PROTEIN FAMILY MEMBER FANCONI ANEMIA GROUP G PROTEIN response to stimulus#GO:0050896;response to stress#GO:0006950;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;Fanconi anaemia nuclear complex#GO:0043240 GORGO|Ensembl=ENSGGOG00000016800.4|UniProtKB=G3RKW5 G3RKW5 CNTN5 PTHR13817:SF80 TITIN INACTIVE TYROSINE-PROTEIN KINASE 7 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000008193.3|UniProtKB=G3QYR1 G3QYR1 ZNF474 PTHR13555:SF67 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER PROTEIN 474 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015437.3|UniProtKB=G3RHE0 G3RHE0 LIN28B PTHR46109:SF3 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG B binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007006.3|UniProtKB=G3QVS9 G3QVS9 PTHR24416:SF294 TYROSINE-PROTEIN KINASE RECEPTOR LEUKOCYTE TYROSINE KINASE RECEPTOR transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;signal transduction#GO:0007165;regulation of neuron differentiation#GO:0045664;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040874.1|UniProtKB=A0A2I2YMB0 A0A2I2YMB0 PTHR11711:SF148 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5C-RELATED GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 intracellular transport#GO:0046907;protein localization to Golgi apparatus#GO:0034067;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein localization to membrane#GO:0072657;protein localization to organelle#GO:0033365 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000022070.2|UniProtKB=G3SHF3 G3SHF3 TRIM7 PTHR24103:SF700 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000022768.2|UniProtKB=G3RM96 G3RM96 ZNF789 PTHR23226:SF412 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008528.4|UniProtKB=G3QZM3 G3QZM3 CEP76 PTHR46436:SF1 CENTROSOMAL PROTEIN OF 76 KDA CENTROSOMAL PROTEIN OF 76 KDA regulation of microtubule-based process#GO:0032886;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007 microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000014846.3|UniProtKB=G3S979 G3S979 EZH2 PTHR45747:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE EZH2 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;binding#GO:0005488;N-methyltransferase activity#GO:0008170;chromatin binding#GO:0003682;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000037655.1|UniProtKB=G3SFV0 G3SFV0 SIRPG PTHR19971:SF6 SIGNAL-REGULATORY PROTEIN BETA SIGNAL-REGULATORY PROTEIN GAMMA positive regulation of cellular component organization#GO:0051130;positive regulation of lymphocyte activation#GO:0051251;positive regulation of cell adhesion#GO:0045785;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;positive regulation of leukocyte activation#GO:0002696;regulation of endocytosis#GO:0030100;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;regulation of multicellular organismal process#GO:0051239;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of cell adhesion#GO:0030155;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;positive regulation of endocytosis#GO:0045807 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011528.3|UniProtKB=G3R7A8 G3R7A8 MTCP1 PTHR15590:SF0 CX9C MOTIF-CONTAINING PROTEIN 4 CX9C MOTIF-CONTAINING PROTEIN 4 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740 GORGO|Ensembl=ENSGGOG00000002607.3|UniProtKB=G3RW38 G3RW38 TERT PTHR12066:SF0 TELOMERASE REVERSE TRANSCRIPTASE TELOMERASE REVERSE TRANSCRIPTASE binding#GO:0005488;nucleic acid binding#GO:0003676;RNA-directed DNA polymerase activity#GO:0003964;RNA binding#GO:0003723;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;telomerase activity#GO:0003720;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleic acid biosynthetic process#GO:0141187;telomere organization#GO:0032200;organelle organization#GO:0006996;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA-templated DNA biosynthetic process#GO:0006278;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;telomere maintenance#GO:0000723 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;ribonucleoprotein complex#GO:1990904;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000005118.3|UniProtKB=A0A2I2ZU69 A0A2I2ZU69 C9H11orf16 PTHR14343:SF3 VWFA DOMAIN-CONTAINING PROTEIN SIMILAR TO HUMAN CHROMOSOME 11 OPEN READING FRAME 16 GORGO|Ensembl=ENSGGOG00000012950.3|UniProtKB=G3RAZ6 G3RAZ6 SERPINB10 PTHR11461:SF175 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B10 endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000013557.3|UniProtKB=G3S0A9 G3S0A9 EEF1G PTHR43986:SF4 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003292.3|UniProtKB=G3QLA9 G3QLA9 FBN1 PTHR24040:SF8 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN FIBRILLIN 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000002921.3|UniProtKB=G3QKA3 G3QKA3 PTHR16201:SF53 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED TRANSMEMBRANE PROTEIN 44 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174 localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;homeostatic process#GO:0042592;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;vacuolar transmembrane transport#GO:0034486;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;chemical homeostasis#GO:0048878;organic acid transport#GO:0015849;transport#GO:0006810;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000008874.3|UniProtKB=G3R0I6 G3R0I6 IFI35 PTHR15225:SF1 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN INTERFERON-INDUCED 35 KDA PROTEIN intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000004294.3|UniProtKB=G3QNT9 G3QNT9 ARRDC3 PTHR11188:SF49 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 3 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000001502.3|UniProtKB=G3QGM4 G3QGM4 SLC12A9 PTHR11827:SF98 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 9 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000043173.1|UniProtKB=A0A2I2YMZ4 A0A2I2YMZ4 PA2G4 PTHR10804:SF130 PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P PROLIFERATION-ASSOCIATED PROTEIN 2G4 protease#PC00190 GORGO|Ensembl=ENSGGOG00000028569.2|UniProtKB=G3SB07 G3SB07 MS4A14 PTHR23320:SF10 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 14 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012881.3|UniProtKB=G3RAT8 G3RAT8 MARCHF7 PTHR14471:SF1 MARCH7/10 E3 UBIQUITIN PROTEIN LIGASE FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF7 protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin binding#GO:0043130;binding#GO:0005488 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000006811.3|UniProtKB=G3QVA5 G3QVA5 CCDC14 PTHR22367:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 14 COILED-COIL DOMAIN-CONTAINING PROTEIN 14 protein localization to centrosome#GO:0071539;protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036;protein localization to organelle#GO:0033365;protein localization to microtubule cytoskeleton#GO:0072698;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to microtubule organizing center#GO:1905508 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriolar satellite#GO:0034451 GORGO|Ensembl=ENSGGOG00000021943.2|UniProtKB=G3S9M0 G3S9M0 FERD3L PTHR23349:SF63 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FER3-LIKE PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000011343.3|UniProtKB=G3R6U0 G3R6U0 OSBP PTHR10972:SF205 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 1 lipid binding#GO:0008289;steroid binding#GO:0005496;binding#GO:0005488;sterol binding#GO:0032934 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000014634.3|UniProtKB=G3RFB5 G3RFB5 WNT8B PTHR12027:SF94 WNT RELATED PROTEIN WNT-8B cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;system development#GO:0048731;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 GORGO|Ensembl=ENSGGOG00000016809.3|UniProtKB=G3RKW7 G3RKW7 AMOTL2 PTHR14826:SF3 ANGIOMOTIN ANGIOMOTIN-LIKE PROTEIN 2 blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;circulatory system development#GO:0072359;response to stimulus#GO:0050896;signaling#GO:0023052;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;hippo signaling#GO:0035329;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;establishment of cell polarity#GO:0030010;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cellular process#GO:0050794;actin filament-based process#GO:0030029;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;system development#GO:0048731;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;developmental process#GO:0032502;regulation of cell migration#GO:0030334 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000043314.1|UniProtKB=A0A2I2Y7B6 A0A2I2Y7B6 PTHR44490:SF1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;kinase activator activity#GO:0019209 regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cellular response to stress#GO:0080135;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of programmed cell death#GO:0043068;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;regulation of response to stress#GO:0080134;positive regulation of apoptotic process#GO:0043065;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 translation factor#PC00223;translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000028577.3|UniProtKB=A0A2I2YJ08 A0A2I2YJ08 CDK15 PTHR24056:SF159 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 15 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;cyclin binding#GO:0030332;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000040844.1|UniProtKB=A0A2I2YUK3 A0A2I2YUK3 ANKRD39 PTHR24171:SF9 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 GORGO|Ensembl=ENSGGOG00000009045.3|UniProtKB=A0A2I2Y288 A0A2I2Y288 CCDC90B PTHR14360:SF14 PROTEIN FMP32, MITOCHONDRIAL COILED-COIL DOMAIN-CONTAINING PROTEIN 90B, MITOCHONDRIAL mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000014958.3|UniProtKB=G3RG55 G3RG55 DUSP23 PTHR23339:SF26 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000023170.2|UniProtKB=G3RVU6 G3RVU6 GDF6 PTHR11848:SF43 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 6 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;renal system development#GO:0072001;kidney development#GO:0001822;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000000201.3|UniProtKB=G3QD88 G3QD88 PTHR11339:SF371 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-2 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000006096.3|UniProtKB=G3QTF6 G3QTF6 STRN3 PTHR15653:SF3 STRIATIN STRIATIN-3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell body#GO:0044297;postsynapse#GO:0098794;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 GORGO|Ensembl=ENSGGOG00000001579.3|UniProtKB=G3QGU3 G3QGU3 EIF3I PTHR19877:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I translation factor activity#GO:0180051;nucleic acid binding#GO:0003676;binding#GO:0005488;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000000169.3|UniProtKB=A0A2I2YZI4 A0A2I2YZI4 PTHR11909:SF139 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA-LIKE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 GORGO|Ensembl=ENSGGOG00000000578.3|UniProtKB=G3QE79 G3QE79 CX3CL1 PTHR12015:SF92 SMALL INDUCIBLE CYTOKINE A FRACTALKINE molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125 immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to peptide#GO:1901652;positive regulation of cell motility#GO:2000147;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to chemical#GO:0042221;taxis#GO:0042330;response to cytokine#GO:0034097;cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;regulation of cell motility#GO:2000145;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;response to external biotic stimulus#GO:0043207;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;cell migration#GO:0016477;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000025641.2|UniProtKB=A0A2I2YK37 A0A2I2YK37 HTR1F PTHR24247:SF34 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1F signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 GORGO|Ensembl=ENSGGOG00000009511.3|UniProtKB=G3R250 G3R250 SLC30A10 PTHR45820:SF3 FI23527P1 CALCIUM_MANGANESE ANTIPORTER SLC30A10 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;zinc ion transmembrane transport#GO:0071577;homeostatic process#GO:0042592;metal ion transport#GO:0030001;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;response to metal ion#GO:0010038;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;detoxification#GO:0098754;monoatomic cation transmembrane transport#GO:0098655;response to chemical#GO:0042221;cellular process#GO:0009987;detoxification of inorganic compound#GO:0061687;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040283.1|UniProtKB=A0A2I2YAL6 A0A2I2YAL6 ZNF518B PTHR24392:SF41 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 518B DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024083.2|UniProtKB=G3S121 G3S121 PTHR47226:SF3 C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4A C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4A regulation of biological process#GO:0050789;response to stress#GO:0006950;biological regulation#GO:0065007;response to stimulus#GO:0050896;blood circulation#GO:0008015;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;inflammatory response#GO:0006954;circulatory system process#GO:0003013;acute inflammatory response#GO:0002526;system process#GO:0003008;defense response#GO:0006952;regulation of biological quality#GO:0065008 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000043706.1|UniProtKB=G3RXM3 G3RXM3 LOC101138091 PTHR23428:SF339 HISTONE H2B HISTONE H2B TYPE 1-N response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000283.3|UniProtKB=G3QDG1 G3QDG1 PTHR23330:SF6 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED WASP HOMOLOG-ASSOCIATED PROTEIN WITH ACTIN, MEMBRANES AND MICROTUBULES binding#GO:0005488;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane#GO:0016020;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000042974.1|UniProtKB=A0A2I2YVV3 A0A2I2YVV3 RNASE7 PTHR11437:SF31 RIBONUCLEASE RIBONUCLEASE 7 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098 defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to Gram-positive bacterium#GO:0050830;defense response to fungus#GO:0050832;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000041433.1|UniProtKB=A0A2I2YHZ4 A0A2I2YHZ4 PTHR10666:SF438 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN ES31 FUSION PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014384.3|UniProtKB=G3REN7 G3REN7 ARL14EP PTHR46536:SF1 ARL14 EFFECTOR PROTEIN ARL14 EFFECTOR PROTEIN GORGO|Ensembl=ENSGGOG00000001586.3|UniProtKB=A0A2I2YNI0 A0A2I2YNI0 LOC101134208 PTHR31837:SF3 CYTOCHROME B-245 CHAPERONE 1 CYTOCHROME B-245 CHAPERONE 1 response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune effector process#GO:0002252;metabolic process#GO:0008152;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000009652.3|UniProtKB=G3R2H4 G3R2H4 KERA PTHR45712:SF13 AGAP008170-PA KERATOCAN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000028554.2|UniProtKB=G3RMA0 G3RMA0 LOC101148972 PTHR11588:SF251 TUBULIN TUBULIN ALPHA-1B CHAIN heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;tubulin#PC00228 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 GORGO|Ensembl=ENSGGOG00000010260.3|UniProtKB=A0A2I2YM77 A0A2I2YM77 PANK4 PTHR12280:SF42 PANTOTHENATE KINASE 4'-PHOSPHOPANTETHEINE PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;kinase activity#GO:0016301;hydrolase activity#GO:0016787;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 GORGO|Ensembl=ENSGGOG00000001606.3|UniProtKB=G3QGW9 G3QGW9 FBXO5 PTHR15493:SF8 F-BOX ONLY PROTEIN 5 AND 43 F-BOX ONLY PROTEIN 5 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of cell cycle process#GO:0090068;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of chromosome segregation#GO:0051985;G1/S transition of mitotic cell cycle#GO:0000082;negative regulation of cell cycle#GO:0045786;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of sister chromatid segregation#GO:0033046;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of chromosome organization#GO:2001251;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of G2/M transition of mitotic cell cycle#GO:0010389;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of mitotic nuclear division#GO:0007088;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic sister chromatid separation#GO:0010965;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of reproductive process#GO:2000241 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000036443.1|UniProtKB=G3QVS2 G3QVS2 PTHR11515:SF25 GLYCOPROTEIN HORMONE BETA CHAIN CHORIOGONADOTROPIN SUBUNIT BETA 3-RELATED molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 system development#GO:0048731;female gonad development#GO:0008585;reproductive system development#GO:0061458;cell communication#GO:0007154;anatomical structure development#GO:0048856;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;reproductive process#GO:0022414;reproductive structure development#GO:0048608;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;developmental process involved in reproduction#GO:0003006;multicellular organism development#GO:0007275;animal organ development#GO:0048513;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;biological regulation#GO:0065007;gonad development#GO:0008406;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;sex differentiation#GO:0007548 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000004855.3|UniProtKB=G3QQ98 G3QQ98 WEE1 PTHR11042:SF72 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 negative regulation of mitotic cell cycle#GO:0045930;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000007680.3|UniProtKB=G3QXH8 G3QXH8 KDM5C PTHR10694:SF43 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5C histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;protein demethylase activity#GO:0140457;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000002062.3|UniProtKB=G3QI34 G3QI34 FASTKD2 PTHR21228:SF1 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA stability#GO:0043487;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membraneless organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000013805.3|UniProtKB=A0A2I2YPD9 A0A2I2YPD9 AMPD1 PTHR11359:SF1 AMP DEAMINASE AMP DEAMINASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137 deaminase#PC00088 GORGO|Ensembl=ENSGGOG00000028177.2|UniProtKB=G3S0Y6 G3S0Y6 XCR1 PTHR10489:SF730 CELL ADHESION MOLECULE CHEMOKINE XC RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930 immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000011231.3|UniProtKB=G3R6J3 G3R6J3 MFSD13A PTHR28658:SF3 TRANSMEMBRANE PROTEIN 180 SOLUTE CARRIER FAMILY 68 MEMBER 1 GORGO|Ensembl=ENSGGOG00000011208.3|UniProtKB=G3R6H4 G3R6H4 GRIN3B PTHR18966:SF364 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3B ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;molecular transducer activity#GO:0060089;channel activity#GO:0015267;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;voltage-gated monoatomic ion channel activity#GO:0005244;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;cell surface receptor signaling pathway#GO:0007166;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Ionotropic glutamate receptor pathway#P00037>NR3#P01009;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071 GORGO|Ensembl=ENSGGOG00000001565.3|UniProtKB=G3QGT0 G3QGT0 PTHR31196:SF2 RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED GORGO|Ensembl=ENSGGOG00000003334.3|UniProtKB=G3QLD1 G3QLD1 TNFAIP3 PTHR13367:SF3 UBIQUITIN THIOESTERASE TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;aminoacyltransferase activity#GO:0016755;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;deubiquitinase activity#GO:0101005;ubiquitin-like protein transferase activity#GO:0019787 positive regulation of signal transduction#GO:0009967;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;catabolic process#GO:0009056;negative regulation of defense response#GO:0031348;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;post-translational protein modification#GO:0043687;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;positive regulation of canonical Wnt signaling pathway#GO:0090263;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of signaling#GO:0023056;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of Wnt signaling pathway#GO:0030177;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;negative regulation of signal transduction#GO:0009968;negative regulation of innate immune response#GO:0045824;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 Toll receptor signaling pathway#P00054>A20#P01348 GORGO|Ensembl=ENSGGOG00000002781.3|UniProtKB=G3QJY1 G3QJY1 DMTF1 PTHR46380:SF2 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000010212.3|UniProtKB=G3R402 G3R402 IARS1 PTHR42780:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000010944.3|UniProtKB=A0A2I2Z4X4 A0A2I2Z4X4 HERC5 PTHR45622:SF7 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 ISG15--PROTEIN LIGASE HERC5 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;ISG15-protein conjugation#GO:0032020;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000017097.3|UniProtKB=G3RLN2 G3RLN2 PM20D1 PTHR45962:SF4 N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1 N-FATTY-ACYL-AMINO ACID SYNTHASE_HYDROLASE PM20D1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 temperature homeostasis#GO:0001659;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;adaptive thermogenesis#GO:1990845;multicellular organismal-level homeostasis#GO:0048871;primary metabolic process#GO:0044238;cellular process#GO:0009987;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000014631.3|UniProtKB=G3RFB2 G3RFB2 SUPT3H PTHR11380:SF16 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription#GO:0006351;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000006000.3|UniProtKB=G3QT64 G3QT64 PBX4 PTHR11850:SF98 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;head development#GO:0060322;embryo development#GO:0009790;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;sensory system development#GO:0048880;eye development#GO:0001654;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;embryonic organ development#GO:0048568;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000009371.3|UniProtKB=A0A2I2Z2K9 A0A2I2Z2K9 RPS2 PTHR13718:SF93 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001152.3|UniProtKB=G3RYH6 G3RYH6 TCEA3 PTHR11477:SF4 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 3 transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007174.3|UniProtKB=G3QW70 G3QW70 H1-3 PTHR11467:SF137 HISTONE H1 HISTONE H1.3 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;DNA binding#GO:0003677;nucleosome binding#GO:0031491;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490 cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;regulation of DNA recombination#GO:0000018;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000009088.3|UniProtKB=G3R138 G3R138 ZNF692 PTHR24406:SF4 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER PROTEIN 692 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007039.3|UniProtKB=A0A2I2ZDC0 A0A2I2ZDC0 PTHR20516:SF1 TRANSMEMBRANE PROTEIN 114/235 FAMILY MEMBER TRANSMEMBRANE PROTEIN 235 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000008467.3|UniProtKB=G3QZJ6 G3QZJ6 CUBN PTHR46806:SF2 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN NEUROPILIN-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 synaptic membrane#GO:0097060;axon#GO:0030424;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;postsynapse#GO:0098794;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590 GORGO|Ensembl=ENSGGOG00000010119.3|UniProtKB=G3R3P6 G3R3P6 FKBP10 PTHR46046:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP10 GORGO|Ensembl=ENSGGOG00000013381.3|UniProtKB=G3RC27 G3RC27 WDR83OS PTHR13193:SF0 CGI-140 PAT COMPLEX SUBUNIT ASTERIX organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000012990.3|UniProtKB=A0A2I2YKJ8 A0A2I2YKJ8 KLHL36 PTHR45632:SF4 LD33804P KELCH-LIKE PROTEIN 36 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;enzyme-substrate adaptor activity#GO:0140767;protein binding#GO:0005515;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004380.3|UniProtKB=G3QP18 G3QP18 ANO7 PTHR12308:SF22 ANOCTAMIN ANOCTAMIN-7 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;endomembrane system organization#GO:0010256;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;lipid localization#GO:0010876 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000043573.1|UniProtKB=A0A2I2Y2G5 A0A2I2Y2G5 PTHR23226:SF74 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 500 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005707.3|UniProtKB=G3QSF3 G3QSF3 TMEM270 PTHR37369:SF1 TRANSMEMBRANE PROTEIN 270 TRANSMEMBRANE PROTEIN 270 GORGO|Ensembl=ENSGGOG00000001435.2|UniProtKB=G3QGG3 G3QGG3 H1-5 PTHR11467:SF24 HISTONE H1 HISTONE H1.5 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490 negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000037467.1|UniProtKB=G3RDV3 G3RDV3 LOC101141336 PTHR48018:SF41 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8J3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008137.3|UniProtKB=G3QYL4 G3QYL4 NR1H4 PTHR48092:SF14 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 1, GROUP H, MEMBER 4 nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000014939.4|UniProtKB=G3RG43 G3RG43 EPHA3 PTHR46877:SF12 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 3 catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858 dendritic tree#GO:0097447;dendrite#GO:0030425;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 GORGO|Ensembl=ENSGGOG00000008005.3|UniProtKB=G3SFP3 G3SFP3 TOB1 PTHR17537:SF6 TRANSDUCER OF ERBB2 TOB PROTEIN TOB1 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000000326.3|UniProtKB=G3QDJ9 G3QDJ9 PTHR48102:SF7 ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED ATP-DEPENDENT CLPX-LIKE CHAPERONE, MITOCHONDRIAL pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ATP-dependent activity#GO:0140657;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP binding#GO:0005524 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190 GORGO|Ensembl=ENSGGOG00000016369.3|UniProtKB=G3RJS1 G3RJS1 SCG5 PTHR12738:SF0 NEUROENDOCRINE PROTEIN 7B2 NEUROENDOCRINE PROTEIN 7B2 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000010437.3|UniProtKB=A0A2I2YVC0 A0A2I2YVC0 SLC25A4 PTHR45635:SF32 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 1 active transmembrane transporter activity#GO:0022804;purine nucleotide transmembrane transporter activity#GO:0015216;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 regulation of membrane permeability#GO:0090559;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008;transport#GO:0006810 membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;organelle membrane#GO:0031090 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000002188.3|UniProtKB=G3QIE4 G3QIE4 ELOC PTHR20648:SF13 ELONGIN-C ELONGIN-C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000006026.3|UniProtKB=G3QT85 G3QT85 ATP13A1 PTHR45630:SF20 CATION-TRANSPORTING ATPASE-RELATED ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE protein carrier activity#GO:0140597;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104 establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;localization within membrane#GO:0051668;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000005654.3|UniProtKB=G3QSA5 G3QSA5 HRH3 PTHR24248:SF210 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR HISTAMINE H3 RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000015505.3|UniProtKB=G3RHK5 G3RHK5 ALKBH8 PTHR13069:SF21 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 TRNA (CARBOXYMETHYLURIDINE(34)-5-O)-METHYLTRANSFERASE ALKBH8 binding#GO:0005488;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000007997.3|UniProtKB=G3QY92 G3QY92 LOC101129658 PTHR10638:SF23 COPPER AMINE OXIDASE AMINE OXIDASE [COPPER-CONTAINING] 3 oxidoreductase activity#GO:0016491;copper ion binding#GO:0005507;catalytic activity#GO:0003824;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 oxidase#PC00175;oxidoreductase#PC00176 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 GORGO|Ensembl=ENSGGOG00000023440.2|UniProtKB=G3SC18 G3SC18 PTHR18929:SF257 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A3 catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853 response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;response to stimulus#GO:0050896;protein folding#GO:0006457;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000009012.3|UniProtKB=G3R0W4 G3R0W4 CCDC12 PTHR31551:SF1 PRE-MRNA-SPLICING FACTOR CWF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 12 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000025644.2|UniProtKB=A0A2I2YV34 A0A2I2YV34 PTHR11229:SF12 50S RIBOSOMAL PROTEIN L3 LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010837.3|UniProtKB=G3R5I6 G3R5I6 CNPPD1 PTHR15615:SF127 FAMILY NOT NAMED PROTEIN CNPPD1 enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000007434.3|UniProtKB=G3S9U4 G3S9U4 PTHR19269:SF68 TROPOMYOSIN TROPOMYOSIN 3 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;muscle contraction#GO:0006936;actin filament organization#GO:0007015;system process#GO:0003008;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;muscle system process#GO:0003012;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;multicellular organismal process#GO:0032501 supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000001245.3|UniProtKB=G3QFY6 G3QFY6 FUT1 PTHR11927:SF4 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE GALACTOSIDE ALPHA-(1,2)-FUCOSYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000001085.3|UniProtKB=G3S926 G3S926 OVCH2 PTHR24251:SF16 OVOCHYMASE-RELATED OVOCHYMASE-2 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000001110.4|UniProtKB=G3QFL8 G3QFL8 LAP3 PTHR11963:SF39 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000003424.3|UniProtKB=A0A2I2YIL5 A0A2I2YIL5 ADGRG2 PTHR12011:SF264 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000027151.2|UniProtKB=G3RQN3 G3RQN3 JRK PTHR19303:SF11 TRANSPOSON JERKY PROTEIN HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000025989.2|UniProtKB=G3RSE3 G3RSE3 BATF2 PTHR23351:SF11 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000014301.3|UniProtKB=G3REG7 G3REG7 NDE1 PTHR10921:SF2 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 establishment of spindle orientation#GO:0051294;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;chromosome localization#GO:0050000;organelle transport along microtubule#GO:0072384;cytoskeleton organization#GO:0007010;establishment of vesicle localization#GO:0051650;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of mitotic spindle localization#GO:0040001;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular localization#GO:0051641;spindle localization#GO:0051653;microtubule-based transport#GO:0099111;nuclear division#GO:0000280;establishment or maintenance of cell polarity#GO:0007163;centrosome localization#GO:0051642;establishment of organelle localization#GO:0051656;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;centrosome cycle#GO:0007098;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;microtubule polymerization#GO:0046785;vesicle cytoskeletal trafficking#GO:0099518;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;establishment of mitotic spindle orientation#GO:0000132;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;cytoskeleton-dependent intracellular transport#GO:0030705;cell migration#GO:0016477;establishment of spindle localization#GO:0051293;vesicle localization#GO:0051648;microtubule polymerization or depolymerization#GO:0031109;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;organelle localization#GO:0051640;cell motility#GO:0048870;microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;establishment of cell polarity#GO:0030010;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049 membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;kinetochore#GO:0000776 GORGO|Ensembl=ENSGGOG00000043979.1|UniProtKB=A0A2I2YZL6 A0A2I2YZL6 PTHR10424:SF72 VIRAL ENVELOPE PROTEIN BC035947 PROTEIN-RELATED animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146;myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;cell differentiation#GO:0030154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000034889.2|UniProtKB=A0A2I2Z340 A0A2I2Z340 ARHGEF33 PTHR46944:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000041978.1|UniProtKB=A0A2I2Z5J4 A0A2I2Z5J4 CRYZL1 PTHR44461:SF1 QUINONE OXIDOREDUCTASE-LIKE PROTEIN 1 FERRY ENDOSOMAL RAB5 EFFECTOR COMPLEX SUBUNIT 4 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016463.4|UniProtKB=G3RK16 G3RK16 EPHA5 PTHR46877:SF13 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 5 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713 cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003779.3|UniProtKB=A0A2I2Y3Z8 A0A2I2Y3Z8 LIMCH1 PTHR15551:SF3 LIM DOMAIN ONLY 7 LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092 regulation of cell-matrix adhesion#GO:0001952;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of cell junction assembly#GO:1901888;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of actin filament bundle assembly#GO:0032231;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053 cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;actin filament bundle#GO:0032432;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000026229.3|UniProtKB=G3SHU7 G3SHU7 KCNT2 PTHR10027:SF9 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 2 transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008016.4|UniProtKB=G3QYB3 G3QYB3 TRMT44 PTHR21210:SF0 TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451 GORGO|Ensembl=ENSGGOG00000002968.3|UniProtKB=G3QKE8 G3QKE8 MAP4K2 PTHR48012:SF6 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCK#P00268;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861 GORGO|Ensembl=ENSGGOG00000003922.3|UniProtKB=G3QMV0 G3QMV0 IPPK PTHR14456:SF2 INOSITOL POLYPHOSPHATE KINASE 1 INOSITOL-PENTAKISPHOSPHATE 2-KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000012153.3|UniProtKB=G3R8Y4 G3R8Y4 IL13RA2 PTHR23036:SF101 CYTOKINE RECEPTOR INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-2 immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000015095.3|UniProtKB=G3RGI9 G3RGI9 PCSK5 PTHR42884:SF7 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 5 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 protein maturation#GO:0051604;gene expression#GO:0010467;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;biosynthetic process#GO:0009058;peptide hormone processing#GO:0016486;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;proteolysis#GO:0006508 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 GORGO|Ensembl=ENSGGOG00000003123.3|UniProtKB=G3QKT7 G3QKT7 SMS PTHR46315:SF2 SPERMINE SYNTHASE SPERMINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058 GORGO|Ensembl=ENSGGOG00000008783.3|UniProtKB=G3R0B0 G3R0B0 PIWIL2 PTHR22891:SF188 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;RNA binding#GO:0003723 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;sexual reproduction#GO:0019953;piRNA processing#GO:0034587;multicellular organismal reproductive process#GO:0048609;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;male gamete generation#GO:0048232;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000025709.2|UniProtKB=G3RT11 G3RT11 SKIC3 PTHR15704:SF7 SUPERKILLER 3 PROTEIN-RELATED SUPERKILLER COMPLEX PROTEIN 3 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009219.3|UniProtKB=G3SJT8 G3SJT8 UNC13D PTHR45999:SF3 UNC-13-4A, ISOFORM B PROTEIN UNC-13 HOMOLOG D transport#GO:0006810;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179 vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 Synaptic vesicle trafficking#P05734>Munc13#P05773 GORGO|Ensembl=ENSGGOG00000005539.3|UniProtKB=G3QS06 G3QS06 GPANK1 PTHR20923:SF1 BAT4 PROTEIN-RELATED G PATCH DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000002399.3|UniProtKB=G3QIY6 G3QIY6 OR8D2 PTHR48018:SF173 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8D2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000875.3|UniProtKB=G3QF01 G3QF01 GPRC5D PTHR14511:SF16 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G PROTEIN-COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER D protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 extracellular region#GO:0005576;signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;vesicle#GO:0031982;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000012407.3|UniProtKB=G3R9M1 G3R9M1 COQ9 PTHR21427:SF19 UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL binding#GO:0005488;lipid binding#GO:0008289 metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000043565.1|UniProtKB=A0A2I2ZCD6 A0A2I2ZCD6 PTHR22932:SF13 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE CS DOMAIN-CONTAINING PROTEIN Hsp90 protein binding#GO:0051879;binding#GO:0005488;protein binding#GO:0005515;heat shock protein binding#GO:0031072;catalytic activity#GO:0003824;protein-folding chaperone binding#GO:0051087;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 protein folding#GO:0006457;ribonucleoprotein complex biogenesis#GO:0022613;small molecule metabolic process#GO:0044281;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;nucleic acid biosynthetic process#GO:0141187;oxoacid metabolic process#GO:0043436;icosanoid biosynthetic process#GO:0046456;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;icosanoid metabolic process#GO:0006690;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;unsaturated fatty acid metabolic process#GO:0033559;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;telomere organization#GO:0032200;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;prostaglandin metabolic process#GO:0006693;chaperone-mediated protein complex assembly#GO:0051131;unsaturated fatty acid biosynthetic process#GO:0006636;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;macromolecule biosynthetic process#GO:0009059;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;monocarboxylic acid biosynthetic process#GO:0072330;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;RNA-templated DNA biosynthetic process#GO:0006278 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000004960.3|UniProtKB=G3QQJ4 G3QQJ4 BTBD16 PTHR46843:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 16 BTB_POZ DOMAIN-CONTAINING PROTEIN 16 GORGO|Ensembl=ENSGGOG00000038789.1|UniProtKB=A0A2I2YQQ4 A0A2I2YQQ4 PTHR12504:SF2 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 SUBFAMILY NOT NAMED macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031 membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000009855.3|UniProtKB=A0A2I2ZPZ7 A0A2I2ZPZ7 BTNL2 PTHR24100:SF105 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000005561.3|UniProtKB=G3QS26 G3QS26 ABCD1 PTHR11384:SF21 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1 carboxylic acid transmembrane transporter activity#GO:0046943;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;nucleotide binding#GO:0000166;monocarboxylic acid transmembrane transporter activity#GO:0008028;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 lipid modification#GO:0030258;establishment of localization#GO:0051234;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;transport#GO:0006810;intracellular transport#GO:0046907;fatty acid metabolic process#GO:0006631;lipid transport#GO:0006869;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;peroxisomal transport#GO:0043574;fatty acid transport#GO:0015908;localization#GO:0051179;lipid oxidation#GO:0034440;carboxylic acid transmembrane transport#GO:1905039;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;fatty acid oxidation#GO:0019395;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;metabolic process#GO:0008152;lipid catabolic process#GO:0016042;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;fatty acid catabolic process#GO:0009062;transmembrane transport#GO:0055085;cellular localization#GO:0051641;peroxisome organization#GO:0007031;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000011714.3|UniProtKB=G3R7S8 G3R7S8 ENTPD2 PTHR11782:SF33 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110 nucleoside diphosphate metabolic process#GO:0009132;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000024081.3|UniProtKB=G3RTL6 G3RTL6 PTPN3 PTHR45706:SF5 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000036653.1|UniProtKB=A0A2I2ZQT0 A0A2I2ZQT0 MRFAP1L2 PTHR31324:SF3 MORF4 FAMILY-ASSOCIATED PROTEIN 1-RELATED MORF4 FAMILY ASSOCIATED PROTEIN 1 LIKE 2 GORGO|Ensembl=ENSGGOG00000037517.1|UniProtKB=A0A2I2ZP69 A0A2I2ZP69 KCNK9 PTHR11003:SF75 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 9 voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 5HT3 type receptor mediated signaling pathway#P04375>K+ channel#P04425;Dopamine receptor mediated signaling pathway#P05912>K+ channel#P05957;Opioid proenkephalin pathway#P05915>K+ channel#P05990;Nicotine pharmacodynamics pathway#P06587>KCNK3/9#P06605;5HT4 type receptor mediated signaling pathway#P04376>K+ channel#P04426;Opioid proopiomelanocortin pathway#P05917>K+ channel#P06009;5HT1 type receptor mediated signaling pathway#P04373>K+ channel#P04407;5HT2 type receptor mediated signaling pathway#P04374>K+ channel#P04413 GORGO|Ensembl=ENSGGOG00000010794.3|UniProtKB=G3R5E7 G3R5E7 CRYBA2 PTHR11818:SF7 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A2 structural molecule activity#GO:0005198 sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000040749.1|UniProtKB=A0A2I2YE15 A0A2I2YE15 SFI1 PTHR22028:SF4 SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN SFI1 HOMOLOG protein binding#GO:0005515;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488 GORGO|Ensembl=ENSGGOG00000042835.1|UniProtKB=A0A2I2ZMY1 A0A2I2ZMY1 PCMT1 PTHR11579:SF7 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE O-methyltransferase activity#GO:0008171;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000040624.1|UniProtKB=A0A2I2YPA5 A0A2I2YPA5 PTHR48225:SF2 HORMA DOMAIN-CONTAINING PROTEIN 1 HORMA DOMAIN-CONTAINING PROTEIN nuclear division#GO:0000280;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;meiosis I#GO:0007127;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;homologous chromosome segregation#GO:0045143;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;regulation of cell cycle process#GO:0010564;homologous chromosome pairing at meiosis#GO:0007129;cell cycle checkpoint signaling#GO:0000075;synaptonemal complex assembly#GO:0007130;cellular component assembly#GO:0022607;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of reproductive process#GO:2000241 condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;synaptonemal structure#GO:0099086;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013472.3|UniProtKB=G3RCB1 G3RCB1 BDKRB1 PTHR24228:SF28 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR B1 BRADYKININ RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 GORGO|Ensembl=ENSGGOG00000000969.3|UniProtKB=A0A2I2YPT8 A0A2I2YPT8 DHDDS PTHR10291:SF51 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 primary metabolic process#GO:0044238;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;isoprenoid metabolic process#GO:0006720 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000034808.2|UniProtKB=G3SKN9 G3SKN9 PTHR18640:SF5 SOLUTE CARRIER FAMILY 10 MEMBER 7 SODIUM_BILE ACID COTRANSPORTER 7 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040802.1|UniProtKB=A0A2I2Y3I6 A0A2I2Y3I6 RYBP PTHR12920:SF3 RYBP AND YAF2-RELATED RING1 AND YY1-BINDING PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000015760.3|UniProtKB=G3RI79 G3RI79 PTHR11691:SF8 TYPE I INTERFERON INTERFERON EPSILON molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;protein binding#GO:0005515;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125 immune system process#GO:0002376;B cell activation involved in immune response#GO:0002312;type I interferon-mediated signaling pathway#GO:0060337;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;natural killer cell activation#GO:0030101;humoral immune response#GO:0006959;B cell activation#GO:0042113;lymphocyte activation involved in immune response#GO:0002285;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;T cell activation involved in immune response#GO:0002286;response to cytokine#GO:0034097;lymphocyte activation#GO:0046649;response to chemical#GO:0042221;defense response to other organism#GO:0098542;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune response#GO:0006955;biological regulation#GO:0065007;adaptive immune response#GO:0002250;response to other organism#GO:0051707;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;interferon superfamily#PC00127 GORGO|Ensembl=ENSGGOG00000001155.3|UniProtKB=G3QFR0 G3QFR0 PTHR24025:SF3 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-3 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000010695.3|UniProtKB=G3R562 G3R562 PTCD2 PTHR14700:SF0 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;regulation of cellular process#GO:0050794;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010543.3|UniProtKB=G3R1N0 G3R1N0 AFF2 PTHR10528:SF18 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;system process#GO:0003008;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;nervous system process#GO:0050877;nucleic acid biosynthetic process#GO:0141187;regulation of biological process#GO:0050789 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000008540.3|UniProtKB=G3QZN5 G3QZN5 CD274 PTHR25466:SF3 T-LYMPHOCYTE ACTIVATION ANTIGEN PROGRAMMED CELL DEATH 1 LIGAND 1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 immune response#GO:0006955;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000009798.3|UniProtKB=G3R2V8 G3R2V8 MATN3 PTHR24034:SF105 EGF-LIKE DOMAIN-CONTAINING PROTEIN MATRILIN-3 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000010964.3|UniProtKB=G3RUE2 G3RUE2 UBTF PTHR46318:SF4 UPSTREAM BINDING TRANSCRIPTION FACTOR NUCLEOLAR TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase I#GO:0006356;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase I#GO:0045943;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;transcription by RNA polymerase I#GO:0006360;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 General transcription by RNA polymerase I#P00022>UBF1#P00655 GORGO|Ensembl=ENSGGOG00000003172.3|UniProtKB=G3QKY4 G3QKY4 SGCE PTHR10132:SF17 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER EPSILON-SARCOGLYCAN cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000038808.1|UniProtKB=A0A2I2YYZ7 A0A2I2YYZ7 PTHR21223:SF4 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 1 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000015335.3|UniProtKB=G3RH50 G3RH50 TREH PTHR23403:SF1 TREHALASE TREHALASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;cellular process#GO:0009987;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000006786.3|UniProtKB=G3S8G6 G3S8G6 TBK1 PTHR22969:SF14 IKB KINASE SERINE_THREONINE-PROTEIN KINASE TBK1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;positive regulation of response to external stimulus#GO:0032103;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;immune system process#GO:0002376;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of type I interferon production#GO:0032481;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to biotic stimulus#GO:0002831;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;positive regulation of biosynthetic process#GO:0009891 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>TBK1#P01361 GORGO|Ensembl=ENSGGOG00000008795.3|UniProtKB=G3R0B6 G3R0B6 COQ5 PTHR43591:SF116 METHYLTRANSFERASE 2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 transferase#PC00220;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000043913.1|UniProtKB=A0A2I2ZJB4 A0A2I2ZJB4 ZNF722 PTHR23226:SF234 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 716 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004204.3|UniProtKB=G3QNL5 G3QNL5 ELP1 PTHR12747:SF0 ELONGATOR COMPLEX PROTEIN 1 ELONGATOR COMPLEX PROTEIN 1 tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;elongator holoenzyme complex#GO:0033588;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 general transcription factor#PC00259 PDGF signaling pathway#P00047>Ikk#P01146 GORGO|Ensembl=ENSGGOG00000002898.3|UniProtKB=G3QK85 G3QK85 CNTNAP5 PTHR15036:SF46 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 5 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;developmental process#GO:0032502;multicellular organism development#GO:0007275 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000013861.3|UniProtKB=A0A2I2YX40 A0A2I2YX40 PTHR11060:SF2 PROTEIN MEMO1 SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000009588.3|UniProtKB=G3R2B6 G3R2B6 ISL1 PTHR24204:SF4 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of transcription by RNA polymerase II#GO:0045944;cell fate specification#GO:0001708;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;axonogenesis#GO:0007409;neuron development#GO:0048666;cell fate commitment#GO:0045165;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;neuron fate commitment#GO:0048663;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06682;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#P06791;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06896 GORGO|Ensembl=ENSGGOG00000002794.3|UniProtKB=G3QK04 G3QK04 MYOM2 PTHR13817:SF22 TITIN MYOMESIN-2 structural molecule activity#GO:0005198 organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 contractile muscle fiber#GO:0043292;A band#GO:0031672;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;M band#GO:0031430;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000014038.3|UniProtKB=G3RDT8 G3RDT8 NOC3L PTHR14428:SF5 NUCLEOLAR COMPLEX PROTEIN 3 NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG binding#GO:0005488;chromatin binding#GO:0003682 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000005888.3|UniProtKB=G3QSW4 G3QSW4 DEGS2 PTHR12879:SF21 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE_C4-MONOOXYGENASE DES2 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672 hydroxylase#PC00122;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009492.3|UniProtKB=G3R238 G3R238 VGLL3 PTHR15950:SF16 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 3 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000038282.1|UniProtKB=A0A2I2YKD5 A0A2I2YKD5 SUSD5 PTHR32493:SF0 SUSHI DOMAIN-CONTAINING PROTEIN 5 SUSHI DOMAIN-CONTAINING PROTEIN 5 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;Notch signaling pathway#GO:0007219;cell surface receptor signaling pathway#GO:0007166 GORGO|Ensembl=ENSGGOG00000004026.3|UniProtKB=G3QN50 G3QN50 SETD5 PTHR46462:SF1 UPSET, ISOFORM A HISTONE-LYSINE N-METHYLTRANSFERASE SETD5 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Rpd3L-Expanded complex#GO:0070210;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000011734.3|UniProtKB=G3R7U8 G3R7U8 SLC19A1 PTHR10686:SF12 FOLATE TRANSPORTER REDUCED FOLATE TRANSPORTER transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;antiporter activity#GO:0015297;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;binding#GO:0005488;carboxylic acid binding#GO:0031406 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;dicarboxylic acid transport#GO:0006835;carboxylic acid transmembrane transport#GO:1905039;vitamin transport#GO:0051180;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;apical plasma membrane#GO:0016324;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical part of cell#GO:0045177 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025865.2|UniProtKB=A0A2I2YA66 A0A2I2YA66 TNIP2 PTHR31882:SF14 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 2 immune response-activating signaling pathway#GO:0002757;response to lipopolysaccharide#GO:0032496;regulation of response to external stimulus#GO:0032101;cellular response to lipid#GO:0071396;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of RNA metabolic process#GO:0051252;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;regulation of cell communication#GO:0010646;innate immune response-activating signaling pathway#GO:0002758;positive regulation of signal transduction#GO:0009967;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;positive regulation of response to external stimulus#GO:0032103;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipopolysaccharide#GO:0071222;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;response to other organism#GO:0051707;activation of innate immune response#GO:0002218;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of innate immune response#GO:0045089;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;intracellular signal transduction#GO:0035556;response to bacterium#GO:0009617;positive regulation of cell communication#GO:0010647;response to external biotic stimulus#GO:0043207;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831 GORGO|Ensembl=ENSGGOG00000006416.2|UniProtKB=G3QU78 G3QU78 BSX PTHR24327:SF35 HOMEOBOX PROTEIN BRAIN-SPECIFIC HOMEOBOX PROTEIN HOMOLOG RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;maintenance of cell number#GO:0098727;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;stem cell population maintenance#GO:0019827;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;feeding behavior#GO:0007631;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000006571.3|UniProtKB=G3QUM7 G3QUM7 RPS18 PTHR10871:SF42 30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN US13 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000015793.3|UniProtKB=A0A2I2YNT8 A0A2I2YNT8 CRTAP PTHR13986:SF3 PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT CARTILAGE-ASSOCIATED PROTEIN collagen binding#GO:0005518;binding#GO:0005488;protein-containing complex binding#GO:0044877 collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000000613.3|UniProtKB=G3QEB2 G3QEB2 GIMAP6 PTHR10903:SF144 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 6 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000010207.3|UniProtKB=G3R3X4 G3R3X4 CCDC196 PTHR37863:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 196-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 196 GORGO|Ensembl=ENSGGOG00000000832.3|UniProtKB=G3QEW6 G3QEW6 FAM53C PTHR28567:SF4 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53C macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nucleocytoplasmic transport#GO:0006913 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008446.3|UniProtKB=G3S7U6 G3S7U6 ADGRG1 PTHR12011:SF318 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G1 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;molecular transducer activity#GO:0060089;heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000012591.3|UniProtKB=G3RA24 G3RA24 CEACAM3 PTHR44427:SF23 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM3 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000015858.3|UniProtKB=A0A2I2ZDV2 A0A2I2ZDV2 TSPAN17 PTHR19282:SF470 TETRASPANIN TETRASPANIN-17 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001160.3|UniProtKB=G3RXB0 G3RXB0 PANK1 PTHR12280:SF23 PANTOTHENATE KINASE PANTOTHENATE KINASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 GORGO|Ensembl=ENSGGOG00000003195.3|UniProtKB=A0A2I2Z3C5 A0A2I2Z3C5 BSCL2 PTHR21212:SF0 BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN SEIPIN cellular process#GO:0009987;lipid storage#GO:0019915;cellular component organization#GO:0016043;lipid droplet organization#GO:0034389;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 GORGO|Ensembl=ENSGGOG00000006702.3|UniProtKB=G3QV03 G3QV03 NDUFAF5 PTHR13090:SF1 ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000007854.3|UniProtKB=G3QXW8 G3QXW8 RAB11FIP3 PTHR15726:SF6 RAB11-FAMILY INTERACTING PROTEIN RAB11 FAMILY-INTERACTING PROTEIN 3 regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;endocytic recycling#GO:0032456;localization within membrane#GO:0051668;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization#GO:0051234 vesicle#GO:0031982;midbody#GO:0030496;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cell division site#GO:0032153;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;recycling endosome#GO:0055037;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cleavage furrow#GO:0032154 GORGO|Ensembl=ENSGGOG00000011719.3|UniProtKB=G3S512 G3S512 AKAP1 PTHR22948:SF75 TUDOR DOMAIN CONTAINING PROTEIN A-KINASE ANCHOR PROTEIN 1, MITOCHONDRIAL protein kinase A regulatory subunit binding#GO:0034237;protein kinase A binding#GO:0051018;binding#GO:0005488;protein binding#GO:0005515 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>AKAP#P07184 GORGO|Ensembl=ENSGGOG00000013660.3|UniProtKB=G3S4P8 G3S4P8 TMEM184C PTHR23423:SF10 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184C transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000034875.2|UniProtKB=G3SKU2 G3SKU2 SMYD3 PTHR12197:SF288 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of macromolecule biosynthetic process#GO:0010558;heart development#GO:0007507;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;circulatory system development#GO:0072359;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000039381.1|UniProtKB=A0A2I2ZUU0 A0A2I2ZUU0 EMP2 PTHR10671:SF32 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 2 plasma membrane bounded cell projection organization#GO:0120036;regulation of cell-substrate adhesion#GO:0010810;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;cellular component assembly#GO:0022607;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell projection assembly#GO:0030031;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;bleb assembly#GO:0032060;plasma membrane bounded cell projection assembly#GO:0120031;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;localization#GO:0051179;regulation of cell-matrix adhesion#GO:0001952;regulation of signaling#GO:0023051;cell adhesion#GO:0007155 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000026819.2|UniProtKB=G3SA82 G3SA82 LGR4 PTHR24372:SF67 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G PROTEIN-COUPLED RECEPTOR 4 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 positive regulation of signaling#GO:0023056;hormone-mediated signaling pathway#GO:0009755;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to chemical#GO:0042221;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;response to hormone#GO:0009725;cell communication#GO:0007154;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of canonical Wnt signaling pathway#GO:0090263;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000001289.3|UniProtKB=A0A2I2Z2Z0 A0A2I2Z2Z0 ZNHIT6 PTHR13483:SF3 BOX C_D SNORNA PROTEIN 1-RELATED BOX C_D SNORNA PROTEIN 1 protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;cellular component assembly#GO:0022607;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000001300.3|UniProtKB=G3QG30 G3QG30 MRPL11 PTHR11661:SF19 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010499.3|UniProtKB=G3RXW1 G3RXW1 LOC101147811 PTHR24356:SF449 SERINE/THREONINE-PROTEIN KINASE 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to oxygen-containing compound#GO:1901700 non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>PDK1/2#P04616;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PDK1#P00831;PI3 kinase pathway#P00048>P110ACT#P01177;Ras Pathway#P04393>PDK#P04555;Interleukin signaling pathway#P00036>PDK1/2#P00985;PI3 kinase pathway#P00048>PDK1#P01196;CCKR signaling map#P06959>PDPK1#P07162;PI3 kinase pathway#P00048>PDK1 ACT#P01190;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PDK1/2#P00903;PDGF signaling pathway#P00047>PDK1/2#P01164;p53 pathway feedback loops 2#P04398>PDK1/2#P04656 GORGO|Ensembl=ENSGGOG00000037468.1|UniProtKB=A0A2I2Y1V0 A0A2I2Y1V0 PTHR24377:SF1054 IP01015P-RELATED ZINC FINGER PROTEIN 655 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016312.3|UniProtKB=G3RSS0 G3RSS0 TBC1D5 PTHR22957:SF337 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 5 GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 retromer complex#GO:0030904;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000002521.3|UniProtKB=G3S4H0 G3S4H0 CALM1 PTHR23048:SF63 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN-LIKE 5 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000013587.3|UniProtKB=G3S617 G3S617 EFHB PTHR12086:SF12 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER B molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 regulation of transport#GO:0051049;regulation of localization#GO:0032879;microtubule-based process#GO:0007017;regulation of response to stimulus#GO:0048583;flagellated sperm motility#GO:0030317;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of monoatomic ion transport#GO:0043269;cellular process#GO:0009987;regulation of calcineurin-NFAT signaling cascade#GO:0070884;cilium movement involved in cell motility#GO:0060294;cilium-dependent cell motility#GO:0060285;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of calcium-mediated signaling#GO:0050848;reproductive process#GO:0022414;regulation of cell communication#GO:0010646;regulation of metal ion transport#GO:0010959;microtubule-based movement#GO:0007018;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;sperm motility#GO:0097722 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;axoneme#GO:0005930;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasmic microtubule#GO:0005881 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000007547.3|UniProtKB=G3RC58 G3RC58 LOC101142418 PTHR24279:SF115 CYTOCHROME P450 CYTOCHROME P450 11B1, MITOCHONDRIAL oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;steroid metabolic process#GO:0008202;response to chemical#GO:0042221;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;regulation of biological quality#GO:0065008;response to oxygen-containing compound#GO:1901700;olefinic compound metabolic process#GO:0120254;cellular response to chemical stimulus#GO:0070887;secondary alcohol metabolic process#GO:1902652;cellular response to hormone stimulus#GO:0032870;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of hormone levels#GO:0010817;ketone metabolic process#GO:0042180;response to endogenous stimulus#GO:0009719;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;response to nitrogen compound#GO:1901698;cellular response to peptide hormone stimulus#GO:0071375;hormone biosynthetic process#GO:0042446;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866 GORGO|Ensembl=ENSGGOG00000012758.3|UniProtKB=A0A2I2YU59 A0A2I2YU59 MTNAP1 PTHR16270:SF5 HYPOTHETICAL LOC287798 MITOCHONDRIAL NUCLEOID-ASSOCIATED PROTEIN 1 GORGO|Ensembl=ENSGGOG00000013054.3|UniProtKB=G3RB89 G3RB89 MMGT1 PTHR21181:SF7 ER membrane protein complex subunit 5-related ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546 GORGO|Ensembl=ENSGGOG00000037832.1|UniProtKB=A0A2I2Y8S0 A0A2I2Y8S0 LOC109028572 PTHR23050:SF383 CALCIUM BINDING PROTEIN CALMODULIN-2 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cation binding#GO:0043169;ion binding#GO:0043167;kinase activator activity#GO:0019209;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 signaling#GO:0023052;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;detection of chemical stimulus#GO:0009593;regulation of transmembrane transport#GO:0034762;calcineurin-mediated signaling#GO:0097720;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to calcium ion#GO:0051592;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;intracellular signaling cassette#GO:0141124;regulation of monoatomic ion transport#GO:0043269;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;detection of stimulus#GO:0051606;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of release of sequestered calcium ion into cytosol#GO:0051279;calcium-mediated signaling#GO:0019722;response to metal ion#GO:0010038;regulation of monoatomic cation transmembrane transport#GO:1904062 microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;myelin sheath#GO:0043209;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;T cell activation#P00053>Calmodulin#P01305;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;B cell activation#P00010>Calmodulin#P00375 GORGO|Ensembl=ENSGGOG00000003052.3|UniProtKB=A0A2I2Y8F9 A0A2I2Y8F9 LMTK2 PTHR24417:SF8 SERINE/THREONINE-PROTEIN KINASE LMTK1 SERINE_THREONINE-PROTEIN KINASE LMTK2 catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000002281.3|UniProtKB=A0A2I2YX04 A0A2I2YX04 PHF19 PTHR12628:SF6 POLYCOMB-LIKE TRANSCRIPTION FACTOR PHD FINGER PROTEIN 19 DNA binding#GO:0003677;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000037035.1|UniProtKB=A0A2I2ZE93 A0A2I2ZE93 PTHR23115:SF254 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000013302.3|UniProtKB=A0A2I2ZL93 A0A2I2ZL93 ASF1B PTHR12040:SF22 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1B histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000034922.2|UniProtKB=G3SKV0 G3SKV0 FAM180A PTHR34034:SF2 PROTEIN FAM180A-RELATED PROTEIN FAM180A GORGO|Ensembl=ENSGGOG00000003063.3|UniProtKB=G3QKN1 G3QKN1 ZSWIM3 PTHR31569:SF3 SWIM-TYPE DOMAIN-CONTAINING PROTEIN ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 3 GORGO|Gene=UBB|UniProtKB=P0CG67 P0CG67 UBB PTHR10666:SF424 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN EL40 FUSION PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000011279.3|UniProtKB=G3R6P2 G3R6P2 NCOA1 PTHR10684:SF1 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 1 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134 cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000023977.2|UniProtKB=G3S6Y3 G3S6Y3 MKRN1 PTHR11224:SF37 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-1 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000010831.3|UniProtKB=G3R5K0 G3R5K0 PTHR48015:SF2 SERINE/THREONINE-PROTEIN KINASE TAO MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 4 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCKR#P00311 GORGO|Ensembl=ENSGGOG00000002738.3|UniProtKB=G3S1Y6 G3S1Y6 CACNA1C PTHR45628:SF10 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1C channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 voltage-gated ion channel#PC00241 Nicotine pharmacodynamics pathway#P06587>CACNA#P06600;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 GORGO|Ensembl=ENSGGOG00000005316.3|UniProtKB=G3QRF4 G3QRF4 CPB1 PTHR11705:SF20 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE B exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000001151.3|UniProtKB=G3QFQ7 G3QFQ7 PTHR10590:SF11 SODIUM/NUCLEOSIDE COTRANSPORTER SODIUM_NUCLEOSIDE COTRANSPORTER 2 nucleoside transmembrane transporter activity#GO:0005337;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;nucleobase-containing compound transmembrane transporter activity#GO:0015932;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate derivative transmembrane transporter activity#GO:1901505;symporter activity#GO:0015293 retina homeostasis#GO:0001895;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;homeostatic process#GO:0042592;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002327.3|UniProtKB=Q8SPF0 Q8SPF0 NDUFA1 PTHR17098:SF2 NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1 membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000022597.2|UniProtKB=G3SA55 G3SA55 ARL14EPL PTHR46804:SF4 ADP RIBOSYLATION FACTOR LIKE GTPASE 14 EFFECTOR PROTEIN LIKE ARL14 EFFECTOR PROTEIN-LIKE small GTPase#PC00208;protein-binding activity modulator#PC00095;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000038930.1|UniProtKB=G3RC73 G3RC73 CFH PTHR45785:SF4 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H-RELATED PROTEIN 3-RELATED binding#GO:0005488;complement binding#GO:0001848;protein binding#GO:0005515 positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;humoral immune response#GO:0006959;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 complement component#PC00078 GORGO|Ensembl=ENSGGOG00000008254.3|UniProtKB=G3QYX1 G3QYX1 RTN4IP1 PTHR11695:SF652 ALCOHOL DEHYDROGENASE RELATED NAD(P)H OXIDOREDUCTASE RTN4IP1, MITOCHONDRIAL catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity#GO:0016491;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000014880.3|UniProtKB=G3SKC4 G3SKC4 LOC101125803 PTHR11417:SF70 SOMATOTROPIN,PROLACTIN CHORIONIC SOMATOMAMMOTROPIN HORMONE 1 signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;hormone receptor binding#GO:0051427;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515 regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to peptide hormone#GO:0043434;positive regulation of response to stimulus#GO:0048584;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of signaling#GO:0023056;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;animal organ development#GO:0048513;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000014508.3|UniProtKB=G3RF01 G3RF01 REXO4 PTHR12801:SF130 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 4 hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA catabolic process#GO:0006308;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000026113.2|UniProtKB=G3SGT9 G3SGT9 ZCCHC14 PTHR16195:SF16 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 14 GORGO|Ensembl=ENSGGOG00000009801.3|UniProtKB=G3R2W1 G3R2W1 CBX2 PTHR46860:SF1 CHROMOBOX PROTEIN HOMOLOG 2 CHROMOBOX PROTEIN HOMOLOG 2 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;histone H3K9me2/3 reader activity#GO:0062072;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;PcG protein complex#GO:0031519;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000013782.3|UniProtKB=G3RD49 G3RD49 LILRB2 PTHR11738:SF117 MHC CLASS I NK CELL RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of immune response#GO:0050776;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010004.3|UniProtKB=G3R3E6 G3R3E6 CCDC150 PTHR35352:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 GORGO|Ensembl=ENSGGOG00000000430.3|UniProtKB=G3QDU5 G3QDU5 ZBTB24 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024137.2|UniProtKB=Q6LDH0 Q6LDH0 HBE1 PTHR11442:SF103 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT EPSILON molecular carrier activity#GO:0140104;binding#GO:0005488;heme binding#GO:0020037;protein binding#GO:0005515;tetrapyrrole binding#GO:0046906 establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;developmental process#GO:0032502;transport#GO:0006810;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;cellular process#GO:0009987;localization#GO:0051179;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;cell development#GO:0048468 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 transfer/carrier protein#PC00219;globin#PC00107 GORGO|Ensembl=ENSGGOG00000028547.2|UniProtKB=G3RT60 G3RT60 LOC101130706 PTHR11431:SF37 FERRITIN FERRITIN HEAVY CHAIN cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;metal ion transport#GO:0030001 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000005518.3|UniProtKB=G3QRZ0 G3QRZ0 SLC4A3 PTHR11453:SF15 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 3 monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000040281.1|UniProtKB=A0A2I2YNA4 A0A2I2YNA4 PTHR12398:SF26 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE INHIBITOR 2 protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 phosphatase inhibitor#PC00183 GORGO|Ensembl=ENSGGOG00000027844.2|UniProtKB=G3S8H3 G3S8H3 LOC101145047 PTHR45935:SF6 PROTEIN ZBED8-RELATED PROTEIN FAM200B GORGO|Ensembl=ENSGGOG00000011092.3|UniProtKB=G3R673 G3R673 MRAS PTHR24070:SF268 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN M-RAS ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Ras#P00552 GORGO|Ensembl=ENSGGOG00000001518.3|UniProtKB=G3QGN8 G3QGN8 PTHR24418:SF369 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ZAP-70 catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 T cell activation#P00053>ZAP-70#P01308 GORGO|Ensembl=ENSGGOG00000009022.3|UniProtKB=G3R0W9 G3R0W9 CD300LD PTHR11860:SF108 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 5 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;immune system process#GO:0002376;regulation of immune response#GO:0050776;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Gene=HRH2|UniProtKB=Q76MS7 Q76MS7 HRH2 PTHR24247:SF263 5-HYDROXYTRYPTAMINE RECEPTOR HISTAMINE H2 RECEPTOR neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 dendritic tree#GO:0097447;dendrite#GO:0030425;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Histamine H2 receptor mediated signaling pathway#P04386>H2#P04489 GORGO|Ensembl=ENSGGOG00000036670.1|UniProtKB=G3S0N1 G3S0N1 PTHR12801:SF22 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED EXONUCLEASE GOR-RELATED nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 exoribonuclease#PC00099;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015083.3|UniProtKB=G3RGH1 G3RGH1 RAB17 PTHR24073:SF912 DRAB5-RELATED RAS-RELATED PROTEIN RAB-17 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular localization#GO:0051641;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;endocytosis#GO:0006897 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000002742.3|UniProtKB=A0A2I2Y3M3 A0A2I2Y3M3 DMTN PTHR24213:SF17 ACTIN-BINDING LIM PROTEIN DEMATIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;actin cytoskeleton#GO:0015629;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000015262.3|UniProtKB=G3RGY1 G3RGY1 TEKT1 PTHR19960:SF25 TEKTIN TEKTIN-1 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000000531.3|UniProtKB=G3QE37 G3QE37 EMC1 PTHR21573:SF0 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 GORGO|Ensembl=ENSGGOG00000043966.1|UniProtKB=A0A2I2Z9Y4 A0A2I2Z9Y4 GLTP PTHR10219:SF74 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN phospholipid binding#GO:0005543;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;ion binding#GO:0043167;lipid carrier activity#GO:0005319;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phospholipid transfer activity#GO:0120014;lipid binding#GO:0008289;lipid transfer activity#GO:0120013 lipid localization#GO:0010876;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;lipid transport#GO:0006869;membrane organization#GO:0061024;ceramide transport#GO:0035627 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000022262.2|UniProtKB=G3RXI3 G3RXI3 HS3ST3A1 PTHR10605:SF64 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 3A1 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000038731.1|UniProtKB=A0A2I2ZWW7 A0A2I2ZWW7 METTL2A PTHR22809:SF4 METHYLTRANSFERASE-RELATED TRNA N(3)-CYTIDINE METHYLTRANSFERASE METTL2A-RELATED catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000011508.3|UniProtKB=G3R790 G3R790 IZUMO3 PTHR36470:SF1 IZUMO SPERM-EGG FUSION PROTEIN 3 IZUMO SPERM-EGG FUSION PROTEIN 3 GORGO|Ensembl=ENSGGOG00000001050.3|UniProtKB=G3RSU5 G3RSU5 PHACTR2 PTHR12751:SF5 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000038539.1|UniProtKB=A0A2I2ZNW7 A0A2I2ZNW7 PTHR10544:SF12 60S RIBOSOMAL PROTEIN L28 LARGE RIBOSOMAL SUBUNIT PROTEIN EL28 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000003851.3|UniProtKB=G3QMN8 G3QMN8 ACER2 PTHR46139:SF1 ALKALINE CERAMIDASE ALKALINE CERAMIDASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;lipid catabolic process#GO:0016042;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000014043.3|UniProtKB=G3RDT6 G3RDT6 ACTG1 PTHR11937:SF414 ACTIN ACTIN, CYTOPLASMIC 1 structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell motility#GO:0048870;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;actin filament#GO:0005884;histone acetyltransferase complex#GO:0000123;cell junction#GO:0030054;neuron projection#GO:0043005;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;NuA4 histone acetyltransferase complex#GO:0035267;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;axon#GO:0030424;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;plasma membrane bounded cell projection#GO:0120025;transferase complex#GO:1990234;cytoskeleton#GO:0005856;intracellular protein-containing complex#GO:0140535;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;membrane#GO:0016020;H4 histone acetyltransferase complex#GO:1902562 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470 GORGO|Ensembl=ENSGGOG00000023366.2|UniProtKB=G3RZJ3 G3RZJ3 PTHR13462:SF16 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803 calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;mitochondrial calcium ion homeostasis#GO:0051560;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular process#GO:0009987;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;transporter complex#GO:1990351;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial protein-containing complex#GO:0098798;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000004444.3|UniProtKB=A0A2I2YLL3 A0A2I2YLL3 RAD51AP1 PTHR15361:SF4 RAD51/NUKS-INTERACTING PROTEIN RAD51-ASSOCIATED PROTEIN 1 single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139 GORGO|Ensembl=ENSGGOG00000040676.1|UniProtKB=A0A2I2ZNP6 A0A2I2ZNP6 PRSS41 PTHR24256:SF564 TRYPTASE-RELATED SERINE PROTEASE 21 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 reproductive process#GO:0022414;gamete generation#GO:0007276;male gamete generation#GO:0048232;cellular process#GO:0009987;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;multicellular organismal reproductive process#GO:0048609;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000008256.3|UniProtKB=G3RSQ1 G3RSQ1 LGMN PTHR12000:SF38 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;catabolic process#GO:0009056;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000004724.3|UniProtKB=G3QPX2 G3QPX2 CTSD PTHR47966:SF42 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CATHEPSIN D catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764 aspartic protease#PC00053;protease#PC00190 GORGO|Ensembl=ENSGGOG00000012595.3|UniProtKB=G3RA37 G3RA37 SMARCA5 PTHR10799:SF997 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5 ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000034896.2|UniProtKB=G3SKU3 G3SKU3 SCRN3 PTHR12994:SF18 SECERNIN SECERNIN-3 GORGO|Ensembl=ENSGGOG00000026291.2|UniProtKB=G3SIV1 G3SIV1 INO80C PTHR31200:SF1 INO80 COMPLEX SUBUNIT C INO80 COMPLEX SUBUNIT C cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011 GORGO|Ensembl=ENSGGOG00000037390.1|UniProtKB=A0A2I2YZK6 A0A2I2YZK6 PTHR12430:SF5 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;nucleic acid transport#GO:0050657;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179 membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000013645.3|UniProtKB=A0A2I2Z5C6 A0A2I2Z5C6 PLOD1 PTHR10730:SF5 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE 1 dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000036489.1|UniProtKB=A0A2I2YUI0 A0A2I2YUI0 PTHR10829:SF25 CORTACTIN AND DREBRIN COACTOSIN-LIKE PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;actin filament#GO:0005884;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000009718.3|UniProtKB=G3R2N8 G3R2N8 ACOT12 PTHR11049:SF3 ACYL COENZYME A THIOESTER HYDROLASE ACETYL-COENZYME A THIOESTERASE hydrolase activity#GO:0016787;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;acetyl-CoA metabolic process#GO:0006084;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000039844.1|UniProtKB=A0A2I2YXW6 A0A2I2YXW6 PTHR31905:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 PROTEIN MIX23 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000041499.1|UniProtKB=A0A2I2YYK8 A0A2I2YYK8 PTHR11759:SF73 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;translation#GO:0006412 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000040530.1|UniProtKB=A0A2I2Y6H0 A0A2I2Y6H0 PTHR23268:SF131 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 19 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000037395.1|UniProtKB=A0A2I2Z061 A0A2I2Z061 THNSL2 PTHR42690:SF3 THREONINE SYNTHASE FAMILY MEMBER THREONINE SYNTHASE-LIKE 2 heterocyclic compound binding#GO:1901363;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824;lyase activity#GO:0016829;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 Threonine biosynthesis#P02781>Threonine synthase#P03190 GORGO|Ensembl=ENSGGOG00000000011.4|UniProtKB=G3QCR7 G3QCR7 NECAB1 PTHR12178:SF11 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 1 regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000017061.3|UniProtKB=G3RLK3 G3RLK3 UTP18 PTHR18359:SF2 WD-REPEAT PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000011766.3|UniProtKB=G3R7Y0 G3R7Y0 KCNK7 PTHR11003:SF31 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 7 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004952.3|UniProtKB=G3RNA6 G3RNA6 ARL8B PTHR45732:SF13 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8B vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;axo-dendritic transport#GO:0008088;vesicle-mediated transport#GO:0016192;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041;axonal transport#GO:0098930;anterograde axonal transport#GO:0008089;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based movement#GO:0007018 vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000025307.2|UniProtKB=G3RVA9 G3RVA9 DCDC2B PTHR23004:SF10 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2B microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000001444.3|UniProtKB=A0A2I2YSF6 A0A2I2YSF6 DBP PTHR11988:SF7 THYROTROPH EMBRYONIC FACTOR RELATED D SITE-BINDING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000039682.1|UniProtKB=A0A2I2YYF6 A0A2I2YYF6 TAMM41 PTHR13619:SF0 PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phosphatidylglycerol biosynthetic process#GO:0006655;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;phospholipid biosynthetic process#GO:0008654;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003886.3|UniProtKB=G3QMR8 G3QMR8 PARD6A PTHR14102:SF9 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG ALPHA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;establishment or maintenance of cell polarity#GO:0007163;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cell-cell junction maintenance#GO:0045217 membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886;apical part of cell#GO:0045177;transferase complex#GO:1990234;protein kinase complex#GO:1902911;apical plasma membrane#GO:0016324;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000025369.2|UniProtKB=G3RZB0 G3RZB0 HSBP1L1 PTHR19424:SF4 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1-LIKE PROTEIN 1 response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266;response to heat#GO:0009408;heat acclimation#GO:0010286;cellular response to heat#GO:0034605;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000004754.3|UniProtKB=G3QQ01 G3QQ01 PGD PTHR11811:SF50 6-PHOSPHOGLUCONATE DEHYDROGENASE 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;phosphogluconate dehydrogenase (decarboxylating) activity#GO:0004616;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;pentose-phosphate shunt, oxidative branch#GO:0009051;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;pentose-phosphate shunt#GO:0006098 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092 Pentose phosphate pathway#P02762>Gluconate Dehydrogenase#P03070 GORGO|Ensembl=ENSGGOG00000015480.3|UniProtKB=G3RHI3 G3RHI3 PSAT1 PTHR43247:SF5 PHOSPHOSERINE AMINOTRANSFERASE PHOSPHOSERINE AMINOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;heterocyclic compound binding#GO:1901363;transaminase activity#GO:0008483;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transaminase#PC00216 Vitamin B6 metabolism#P02787>Phosphoserine transaminase#P03227;Serine glycine biosynthesis#P02776>Phosphoserine aminotransferase#P03157;Pyridoxal-5-phosphate biosynthesis#P02759>Phosphohydroxythreonine aminotransferase#P03058 GORGO|Ensembl=ENSGGOG00000008958.3|UniProtKB=G3R0R2 G3R0R2 GJB4 PTHR11984:SF30 CONNEXIN GAP JUNCTION BETA-4 PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020 cell junction protein#PC00070;gap junction#PC00105 GORGO|Ensembl=ENSGGOG00000016959.3|UniProtKB=G3RLB1 G3RLB1 PTH2R PTHR45620:SF7 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE 2 RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012234.3|UniProtKB=G3R953 G3R953 RPS12 PTHR11843:SF19 40S RIBOSOMAL PROTEIN S12 SMALL RIBOSOMAL SUBUNIT PROTEIN ES12 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;translation#GO:0006412;ribosomal small subunit biogenesis#GO:0042274;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component biogenesis#GO:0044085 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001163.3|UniProtKB=G3QFR8 G3QFR8 DAGLA PTHR45792:SF13 DIACYLGLYCEROL LIPASE HOMOLOG-RELATED DIACYLGLYCEROL LIPASE-ALPHA hydrolase activity#GO:0016787;triacylglycerol lipase activity#GO:0004806;lipase activity#GO:0016298;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 unsaturated fatty acid metabolic process#GO:0033559;metabolic process#GO:0008152;acylglycerol catabolic process#GO:0046464;multicellular organism development#GO:0007275;lipid catabolic process#GO:0016042;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;synaptic signaling#GO:0099536;nervous system development#GO:0007399;icosanoid metabolic process#GO:0006690;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;glycerolipid catabolic process#GO:0046503;animal gross anatomical part developmental process#GO:0160108;regulation of biological process#GO:0050789;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;signaling#GO:0023052;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;glycerolipid metabolic process#GO:0046486;neutral lipid catabolic process#GO:0046461;developmental process#GO:0032502;lipid metabolic process#GO:0006629;acylglycerol metabolic process#GO:0006639;fatty acid metabolic process#GO:0006631;neurogenesis#GO:0022008;neutral lipid metabolic process#GO:0006638;cellular developmental process#GO:0048869;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;trans-synaptic signaling#GO:0099537;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;primary metabolic process#GO:0044238;catabolic process#GO:0009056 dendritic tree#GO:0097447;leading edge membrane#GO:0031256;postsynaptic membrane#GO:0045211;dendrite#GO:0030425;cell projection membrane#GO:0031253;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection membrane#GO:0032589;synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane region#GO:0098590 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 2-arachidonoylglycerol biosynthesis#P05726>DGL#P05736 GORGO|Ensembl=ENSGGOG00000006387.3|UniProtKB=G3QU53 G3QU53 IL1B PTHR10078:SF30 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 BETA molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of intracellular signal transduction#GO:1902533;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;positive regulation of cell adhesion#GO:0045785;positive regulation of cell communication#GO:0010647;response to external biotic stimulus#GO:0043207;response to bacterium#GO:0009617;positive regulation of lymphocyte proliferation#GO:0050671;inflammatory response#GO:0006954;cell communication#GO:0007154;positive regulation of cell-cell adhesion#GO:0022409;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;positive regulation of T cell activation#GO:0050870;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of T cell activation#GO:0050863;response to lipid#GO:0033993;regulation of multicellular organismal process#GO:0051239;regulation of MAPK cascade#GO:0043408;positive regulation of leukocyte activation#GO:0002696;cell surface receptor signaling pathway#GO:0007166;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;positive regulation of T cell proliferation#GO:0042102;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of lymphocyte activation#GO:0051249;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte proliferation#GO:0070665;regulation of response to stimulus#GO:0048583;defense response#GO:0006952;positive regulation of signal transduction#GO:0009967;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;regulation of T cell proliferation#GO:0042129;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cytokine-mediated signaling pathway#GO:0019221;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;response to biotic stimulus#GO:0009607;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of ERK1 and ERK2 cascade#GO:0070372;cellular response to lipid#GO:0071396;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;response to lipopolysaccharide#GO:0032496;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 GORGO|Ensembl=ENSGGOG00000013146.3|UniProtKB=A0A2I2ZA10 A0A2I2ZA10 PABPC3 PTHR24012:SF680 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 3 single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;mRNA binding#GO:0003729 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000022062.2|UniProtKB=G3RXS5 G3RXS5 PTHR11205:SF32 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;binding#GO:0005488;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000011803.3|UniProtKB=A0A2I2YBH9 A0A2I2YBH9 SMARCE1 PTHR46232:SF2 SMARCE1 REGULATOR OF CHROMATIN SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1 DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;binding#GO:0005488 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000037482.1|UniProtKB=A0A2I2Y5F6 A0A2I2Y5F6 C8H10orf105 PTHR38325:SF1 MCG55969 GENE, 17455-RELATED GORGO|Ensembl=ENSGGOG00000021963.2|UniProtKB=G3RMD6 G3RMD6 CDCP1 PTHR14477:SF1 CUB DOMAIN-CONTAINING PROTEIN 1 CUB DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000013161.3|UniProtKB=A0A2I2ZTP9 A0A2I2ZTP9 CDIN1 PTHR31661:SF2 SIMILAR TO CDNA SEQUENCE BC052040 CDAN1-INTERACTING NUCLEASE 1 anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;immune system process#GO:0002376;developmental process#GO:0032502;homeostasis of number of cells#GO:0048872;multicellular organismal process#GO:0032501;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592;hemopoiesis#GO:0030097;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013890.3|UniProtKB=G3RDE0 G3RDE0 PSKH1 PTHR24347:SF254 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000001907.3|UniProtKB=G3QHP2 G3QHP2 TMEM179B PTHR31056:SF1 TRANSMEMBRANE PROTEIN 179B TRANSMEMBRANE PROTEIN 179B GORGO|Ensembl=ENSGGOG00000022629.2|UniProtKB=G3S8S7 G3S8S7 MLF1 PTHR13105:SF22 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR 1 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000022110.2|UniProtKB=G3SHA5 G3SHA5 LOC101146307 PTHR13526:SF17 TRANSCRIPTION FACTOR SPT20 HOMOLOG TRANSCRIPTION FACTOR SPT20 HOMOLOG-LIKE 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;chromatin#GO:0000785;SAGA complex#GO:0000124;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000016974.3|UniProtKB=G3RLC8 G3RLC8 HIVEP3 PTHR45944:SF5 SCHNURRI, ISOFORM F TRANSCRIPTION FACTOR HIVEP3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000000118.3|UniProtKB=G3QD14 G3QD14 RUFY2 PTHR45956:SF3 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000131.3|UniProtKB=G3S9Q9 G3S9Q9 RPL10 PTHR11726:SF36 60S RIBOSOMAL PROTEIN L10 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011534.3|UniProtKB=G3R7C6 G3R7C6 KCNU1 PTHR10027:SF23 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY U MEMBER 1 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;calcium-activated potassium channel activity#GO:0015269;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;potassium ion transport#GO:0006813;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024718.2|UniProtKB=A0A2I2YDD7 A0A2I2YDD7 ZNF142 PTHR24392:SF60 ZINC FINGER PROTEIN ZINC FINGER Y-CHROMOSOMAL PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000009615.3|UniProtKB=G3R2E1 G3R2E1 SSBP1 PTHR10302:SF0 SINGLE-STRANDED DNA-BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN, MITOCHONDRIAL molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;DNA binding#GO:0003677;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697 positive regulation of DNA replication#GO:0045740;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;DNA replication#GO:0006260;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;primary metabolic process#GO:0044238;positive regulation of DNA metabolic process#GO:0051054;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;regulation of DNA replication#GO:0006275 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial nucleoid#GO:0042645;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoid#GO:0009295;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000012387.3|UniProtKB=G3R9K2 G3R9K2 TBATA PTHR33772:SF3 THYMUS, BRAIN AND TESTES-ASSOCIATED PROTEIN TBATA GORGO|Ensembl=ENSGGOG00000005599.3|UniProtKB=G3QS70 G3QS70 CUL9 PTHR22771:SF2 CULLIN AND GALACTOSE-BINDING DOMAIN-CONTAINING CULLIN-9 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of nuclear division#GO:0051783;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;regulation of mitotic nuclear division#GO:0007088;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000005376.3|UniProtKB=G3QRL1 G3QRL1 GSTA4 PTHR11571:SF123 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE A4 transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;glutathione metabolic process#GO:0006749;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000028295.2|UniProtKB=G3RY61 G3RY61 YPEL PTHR13848:SF17 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 4 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000043568.1|UniProtKB=G3S4Q3 G3S4Q3 RPL32 PTHR23413:SF6 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N LARGE RIBOSOMAL SUBUNIT PROTEIN EL32 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009789.3|UniProtKB=A0A2I2YG57 A0A2I2YG57 TMTC1 PTHR44809:SF1 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE TMTC1 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000005048.3|UniProtKB=G3QQS3 G3QQS3 STX2 PTHR19957:SF36 SYNTAXIN SYNTAXIN-2 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;exocytosis#GO:0006887;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;secretion by cell#GO:0032940;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;cellular component organization#GO:0016043;export from cell#GO:0140352;vesicle fusion#GO:0006906 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 GORGO|Ensembl=ENSGGOG00000024837.2|UniProtKB=G3S4D6 G3S4D6 ZFHX4 PTHR45891:SF2 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000004250.3|UniProtKB=G3QNQ8 G3QNQ8 TDRD1 PTHR22948:SF4 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 1 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;piRNA processing#GO:0034587;pattern specification process#GO:0007389;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;regionalization#GO:0003002;male gamete generation#GO:0048232;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;spermatogenesis#GO:0007283;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;cell maturation#GO:0048469;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;embryonic pattern specification#GO:0009880;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;embryo development#GO:0009790;oogenesis#GO:0048477;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;anterior/posterior pattern specification#GO:0009952;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anterior/posterior axis specification#GO:0009948 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015055.3|UniProtKB=G3RGE8 G3RGE8 MRPS16 PTHR12919:SF41 30S RIBOSOMAL PROTEIN S16 SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000015361.3|UniProtKB=G3RH71 G3RH71 WSB1 PTHR15622:SF12 WD40 REPEAT PROTEIN WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 1 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209 GORGO|Ensembl=ENSGGOG00000016679.3|UniProtKB=G3RKK7 G3RKK7 LPP PTHR24207:SF0 ZYX102 PROTEIN LIPOMA-PREFERRED PARTNER cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 actomyosin#GO:0042641;actin cytoskeleton#GO:0015629;cell-substrate junction#GO:0030055;intracellular membraneless organelle#GO:0043232;focal adhesion#GO:0005925;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228 kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000000215.3|UniProtKB=G3QDA2 G3QDA2 C19H17orf107 PTHR38506:SF1 RIKEN CDNA 4930544D05 GENE RIKEN CDNA 4930544D05 GENE GORGO|Ensembl=ENSGGOG00000004985.3|UniProtKB=G3QQL6 G3QQL6 LOC101149649 PTHR43829:SF15 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-7 carbohydrate transmembrane transporter activity#GO:0015144;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;passive transmembrane transporter activity#GO:0022803 organic hydroxy compound transport#GO:0015850;fluid transport#GO:0042044;water transport#GO:0006833;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006050.3|UniProtKB=G3QTA8 G3QTA8 TNNT1 PTHR11521:SF6 TROPONIN T TROPONIN T, SLOW SKELETAL MUSCLE binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;striated muscle contraction#GO:0006941;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;neuromuscular process#GO:0050905;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;developmental process#GO:0032502;muscle contraction#GO:0006936;system process#GO:0003008;cellular developmental process#GO:0048869;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell development#GO:0048468;actomyosin structure organization#GO:0031032;skeletal muscle contraction#GO:0003009;cell differentiation#GO:0030154;nervous system process#GO:0050877;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000027678.2|UniProtKB=G3SCN1 G3SCN1 PTHR13800:SF8 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 7 passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;transferase activity#GO:0016740;transporter activity#GO:0005215;kinase activity#GO:0016301;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium ion transmembrane transporter activity#GO:0015085;protein kinase activity#GO:0004672;monoatomic cation transmembrane transporter activity#GO:0008324 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025787.2|UniProtKB=G3RTI4 G3RTI4 PTHR12138:SF75 PRIMATE-EXPANDED PROTEIN FAMILY TRANSMEMBRANE PROTEIN GORGO|Ensembl=ENSGGOG00000013737.4|UniProtKB=G3RD05 G3RD05 GFRA2 PTHR10269:SF4 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-2 cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;system development#GO:0048731;nervous system development#GO:0007399 signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006975.4|UniProtKB=A0A2I2ZQA2 A0A2I2ZQA2 PDE4D PTHR11347:SF91 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4D catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000004364.3|UniProtKB=G3QP00 G3QP00 SLC24A3 PTHR10846:SF42 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000004307.3|UniProtKB=A0A2I2ZAI0 A0A2I2ZAI0 DHX30 PTHR18934:SF229 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX30 ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;helicase activity#GO:0004386 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000006814.3|UniProtKB=G3RMF2 G3RMF2 SMARCD2 PTHR13844:SF2 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000001066.3|UniProtKB=G3QFH7 G3QFH7 SPATA4 PTHR12509:SF8 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 4 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000010945.3|UniProtKB=G3R5U1 G3R5U1 VPS9D1 PTHR23101:SF98 RAB GDP/GTP EXCHANGE FACTOR VPS9 DOMAIN-CONTAINING PROTEIN 1 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000006829.3|UniProtKB=G3QVB9 G3QVB9 KLHL21 PTHR24412:SF255 KELCH PROTEIN KELCH-LIKE PROTEIN 21 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013088.3|UniProtKB=A0A2I2ZMV2 A0A2I2ZMV2 AAMDC PTHR15811:SF5 MTH938 DOMAIN-CONTAINING PROTEIN MTH938 DOMAIN-CONTAINING PROTEIN positive regulation of developmental process#GO:0051094;positive regulation of fat cell differentiation#GO:0045600;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000017063.3|UniProtKB=G3RLK1 G3RLK1 KRT39 PTHR23239:SF106 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 39 structural molecule activity#GO:0005198 tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000012352.3|UniProtKB=G3R9G9 G3R9G9 TOLLIP PTHR16461:SF5 TOLL-INTERACTING PROTEIN TOLL-INTERACTING PROTEIN binding#GO:0005488;ubiquitin binding#GO:0043130;enzyme binding#GO:0019899;protein binding#GO:0005515 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Toll receptor signaling pathway#P00054>Tollip#P01379 GORGO|Ensembl=ENSGGOG00000001171.3|UniProtKB=G3S7B4 G3S7B4 ITIH5 PTHR10338:SF62 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H5 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000034831.2|UniProtKB=G3SKG0 G3SKG0 NDST3 PTHR10605:SF29 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 3 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;deacetylase activity#GO:0019213;transferase activity#GO:0016740;catalytic activity#GO:0003824;deacylase activity#GO:0160215 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000022590.2|UniProtKB=G3RV57 G3RV57 HTR1B PTHR24247:SF16 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1B signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594 signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000043086.1|UniProtKB=A0A2I2ZPR4 A0A2I2ZPR4 PPM1E PTHR13832:SF535 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1E hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament bundle assembly#GO:0032231;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000016056.3|UniProtKB=G3RIZ8 G3RIZ8 BIN1 PTHR46514:SF4 AMPHIPHYSIN MYC BOX-DEPENDENT-INTERACTING PROTEIN 1 cytoskeletal protein binding#GO:0008092;binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein binding#GO:0005515 cell junction#GO:0030054;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;presynapse#GO:0098793;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000009502.3|UniProtKB=A0A2I2Y2G1 A0A2I2Y2G1 PTHR48112:SF16 HIGH MOBILITY GROUP PROTEIN DSP1 HMG BOX DOMAIN-CONTAINING PROTEIN cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000008541.3|UniProtKB=G3QZN4 G3QZN4 RCVRN PTHR23055:SF20 CALCIUM BINDING PROTEINS RECOVERIN metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Recoverin#P00756 GORGO|Ensembl=ENSGGOG00000008300.3|UniProtKB=G3QZ10 G3QZ10 LRRC3C PTHR46473:SF3 GH08155P LEUCINE RICH REPEAT CONTAINING 3C voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;gated channel activity#GO:0022836;potassium channel regulator activity#GO:0015459;voltage-gated potassium channel activity#GO:0005249;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;molecular function activator activity#GO:0140677;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;transmembrane transporter binding#GO:0044325;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 GORGO|Ensembl=ENSGGOG00000003894.3|UniProtKB=G3SB46 G3SB46 LOC101149513 PTHR24302:SF48 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A4 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016227.3|UniProtKB=A0A2I2Y8H5 A0A2I2Y8H5 PTHR11256:SF54 BCL-2 RELATED BCL-2 HOMOLOGOUS ANTAGONIST_KILLER passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267 negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968 GORGO|Ensembl=ENSGGOG00000024834.2|UniProtKB=G3S5N8 G3S5N8 SLITRK1 PTHR45773:SF7 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 1 positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;regulation of synapse organization#GO:0050807;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell junction assembly#GO:1901888;system development#GO:0048731;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501 cell junction#GO:0030054;synaptic membrane#GO:0097060;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;GABA-ergic synapse#GO:0098982;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000554.3|UniProtKB=G3QE59 G3QE59 KCNJ4 PTHR11767:SF53 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 4 monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836 potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000006076.3|UniProtKB=Q0MQB3 Q0MQB3 NDUFA9 PTHR12126:SF10 NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL binding#GO:0005488;protein-containing complex binding#GO:0044877 metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009191.3|UniProtKB=G3R1C1 G3R1C1 TP53INP1 PTHR31671:SF0 DIABETES AND OBESITY REGULATED, ISOFORM G TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495;transcription coactivator activity#GO:0003713 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;macroautophagy#GO:0016236;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;vacuole organization#GO:0007033;organelle assembly#GO:0070925;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;process utilizing autophagic mechanism#GO:0061919;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000010646.3|UniProtKB=G3R518 G3R518 MCOLN1 PTHR12127:SF6 MUCOLIPIN MUCOLIPIN-1 gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000011765.3|UniProtKB=G3R7X9 G3R7X9 PDZK1IP1 PTHR15296:SF0 MEMBRANE-ASSOCIATED PROTEIN MAP17 PDZK1-INTERACTING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000005100.3|UniProtKB=G3QQX1 G3QQX1 ANKFN1 PTHR21437:SF3 WIDE AWAKE ANKYRIN REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 1 mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of establishment or maintenance of cell polarity#GO:0032878;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;localization#GO:0051179;spindle localization#GO:0051653;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043 cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000010139.3|UniProtKB=G3R3R2 G3R3R2 CNNM4 PTHR12064:SF26 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM4 monoatomic cation transmembrane transporter activity#GO:0008324;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;magnesium ion transmembrane transporter activity#GO:0015095 monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;magnesium ion transport#GO:0015693;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;metal ion transport#GO:0030001 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011217.3|UniProtKB=G3R6I2 G3R6I2 TMEM259 PTHR21650:SF4 MEMBRALIN/KINETOCHORE PROTEIN NUF2 MEMBRALIN positive regulation of protein catabolic process#GO:0045732;regulation of cellular response to stress#GO:0080135;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;response to endoplasmic reticulum stress#GO:0034976;regulation of ERAD pathway#GO:1904292;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of response to endoplasmic reticulum stress#GO:1905897;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of response to stimulus#GO:0048584;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000000776.3|UniProtKB=G3QER5 G3QER5 IFI6 PTHR16932:SF25 INTERFERON ALPHA-INDUCIBLE PROTEIN 27 INTERFERON ALPHA-INDUCIBLE PROTEIN 6 intracellular signal transduction#GO:0035556;apoptotic signaling pathway#GO:0097190;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cell death#GO:0008219;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;signal transduction#GO:0007165;regulation of biological process#GO:0050789;programmed cell death#GO:0012501 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011150.3|UniProtKB=A0A2I2YLK6 A0A2I2YLK6 KANSL1L PTHR22443:SF16 NON-SPECIFIC LETHAL 1, ISOFORM M KAT8 REGULATORY NSL COMPLEX SUBUNIT 1-LIKE PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515 organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;NSL complex#GO:0044545;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000037261.1|UniProtKB=A0A2I2ZSN7 A0A2I2ZSN7 PTHR12391:SF5 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000003084.3|UniProtKB=G3SF57 G3SF57 MIEF2 PTHR16451:SF11 MITOCHONDRIAL DYNAMICS PROTEINS 49/51 FAMILY MEMBER MITOCHONDRIAL DYNAMICS PROTEIN MID49 positive regulation of cellular component organization#GO:0051130;positive regulation of developmental process#GO:0051094;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of mitochondrion organization#GO:0010821;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;biological regulation#GO:0065007;regulation of developmental process#GO:0050793 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967 GORGO|Ensembl=ENSGGOG00000015964.3|UniProtKB=G3RIQ7 G3RIQ7 KCTD19 PTHR14499:SF20 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD19 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007498.3|UniProtKB=G3QX29 G3QX29 MYH15 PTHR45615:SF26 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-15 macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000008723.3|UniProtKB=A0A2I2ZN59 A0A2I2ZN59 ARHGEF12 PTHR45872:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 12 protein binding#GO:0005515;enzyme regulator activity#GO:0030234;signaling receptor binding#GO:0005102;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;G protein-coupled receptor binding#GO:0001664 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000001674.3|UniProtKB=G3QH33 G3QH33 PHF20 PTHR15856:SF27 PHD FINGER PROTEIN 20-RELATED PHD FINGER PROTEIN 20 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 chromosome#GO:0005694;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;NSL complex#GO:0044545;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000016780.4|UniProtKB=G3RKU0 G3RKU0 ZPBP PTHR15443:SF5 ZONA PELLUCIDA BINDING PROTEIN SP38 ZONA PELLUCIDA-BINDING PROTEIN 1 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;fertilization#GO:0009566;gamete generation#GO:0007276;cell differentiation#GO:0030154;acrosome assembly#GO:0001675;spermatid differentiation#GO:0048515;cellular process#GO:0009987;single fertilization#GO:0007338;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;cell-cell recognition#GO:0009988;anatomical structure formation involved in morphogenesis#GO:0048646;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cell recognition#GO:0008037;spermatid development#GO:0007286;sexual reproduction#GO:0019953;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;binding of sperm to zona pellucida#GO:0007339;male gamete generation#GO:0048232;spermatogenesis#GO:0007283;developmental process#GO:0032502;sperm-egg recognition#GO:0035036;cellular developmental process#GO:0048869 intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000024456.2|UniProtKB=G3S1M4 G3S1M4 PTHR23267:SF315 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-1 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000011916.3|UniProtKB=G3R8D6 G3R8D6 SUPT20H PTHR13526:SF18 TRANSCRIPTION FACTOR SPT20 HOMOLOG TRANSCRIPTION FACTOR SPT20 HOMOLOG transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;SAGA complex#GO:0000124;chromatin#GO:0000785;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000014904.3|UniProtKB=G3RG09 G3RG09 ENTPD6 PTHR11782:SF99 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 6 ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434;metabolic process#GO:0008152;nucleoside diphosphate metabolic process#GO:0009132 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000006891.3|UniProtKB=G3QVH3 G3QVH3 ZNF202 PTHR23226:SF195 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 202 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007813.3|UniProtKB=G3QXS7 G3QXS7 TMEM9B PTHR13064:SF2 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER TRANSMEMBRANE PROTEIN 9B GORGO|Ensembl=ENSGGOG00000024497.2|UniProtKB=A0A2I2ZRN9 A0A2I2ZRN9 PTHR21245:SF16 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RRM DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000042405.1|UniProtKB=A0A2I2YK90 A0A2I2YK90 RTEL1 PTHR11472:SF61 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER HELICASE ATP-BINDING DOMAIN-CONTAINING PROTEIN nucleotide binding#GO:0000166;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;nucleic acid conformation isomerase activity#GO:0120545;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488 telomere organization#GO:0032200;regulation of double-strand break repair#GO:2000779;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA recombination#GO:0045910;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;regulation of telomere maintenance#GO:0032204;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular response to stress#GO:0080135;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA helicase#PC00011 GORGO|Ensembl=ENSGGOG00000042226.1|UniProtKB=A0A2I2YQ77 A0A2I2YQ77 PTHR22245:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 144A-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 144A-RELATED GORGO|Ensembl=ENSGGOG00000040885.1|UniProtKB=A0A2I2YFL3 A0A2I2YFL3 TPRX2 PTHR45793:SF21 HOMEOBOX PROTEIN TETRAPEPTIDE REPEAT HOMEOBOX PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000002042.3|UniProtKB=G3QI27 G3QI27 ADAM22 PTHR11905:SF14 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 22 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;cell junction#GO:0030054 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000009127.3|UniProtKB=G3R164 G3R164 MNAT1 PTHR12683:SF13 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 response to stimulus#GO:0050896;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974 transferase complex#GO:1990234;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000027232.2|UniProtKB=G3SCT6 G3SCT6 PTHR20879:SF1 INTERLEUKIN-27 SUBUNIT ALPHA INTERLEUKIN-27 SUBUNIT ALPHA cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of leukocyte proliferation#GO:0070663;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of T cell activation#GO:0050863;regulation of lymphocyte proliferation#GO:0050670;regulation of cell development#GO:0060284;regulation of mononuclear cell proliferation#GO:0032944;regulation of immune effector process#GO:0002697;regulation of hemopoiesis#GO:1903706;regulation of cell population proliferation#GO:0042127;regulation of immune response#GO:0050776;regulation of lymphocyte activation#GO:0051249;regulation of developmental process#GO:0050793;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of T cell proliferation#GO:0042129;regulation of multicellular organismal development#GO:2000026;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000000331.3|UniProtKB=G3QDK2 G3QDK2 PTHR16431:SF3 NEUROGENIC PROTEIN MASTERMIND PROTEIN MIS18-BETA chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;kinetochore organization#GO:0051383;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775 GORGO|Ensembl=ENSGGOG00000009484.3|UniProtKB=A0A2I2ZPM4 A0A2I2ZPM4 PTHR42738:SF5 HYDROXYMETHYLGLUTARYL-COA LYASE 3-HYDROXY-3-METHYLGLUTARYL-COA LYASE, CYTOPLASMIC carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;lyase activity#GO:0016829 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;lipid biosynthetic process#GO:0008610;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytosol#GO:0005829 lyase#PC00144 GORGO|Ensembl=ENSGGOG00000007528.3|UniProtKB=A0A2I2ZWR5 A0A2I2ZWR5 SEPTIN12 PTHR18884:SF66 SEPTIN SEPTIN-12 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cell cycle process#GO:0022402;cellular process#GO:0009987;cell division#GO:0051301;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179 microtubule cytoskeleton#GO:0015630;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000044040.1|UniProtKB=A0A2I2ZNU5 A0A2I2ZNU5 FGL2 PTHR19143:SF189 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBROLEUKIN cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000015411.3|UniProtKB=G3RHC6 G3RHC6 CDC16 PTHR12558:SF9 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 16 HOMOLOG enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome segregation#GO:0051983;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of cell cycle#GO:0045787;proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;cell division#GO:0051301;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell cycle phase transition#GO:1901987;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;regulation of nuclear division#GO:0051783;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;cytoplasm#GO:0005737;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016119.3|UniProtKB=G3RVG4 G3RVG4 SPG7 PTHR43655:SF8 ATP-DEPENDENT PROTEASE MITOCHONDRIAL INNER MEMBRANE M-AAA PROTEASE COMPONENT PARAPLEGIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000008536.3|UniProtKB=G3QZN6 G3QZN6 CCDC146 PTHR32083:SF34 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 146 organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000000853.3|UniProtKB=G3QEY4 G3QEY4 PGLYRP3 PTHR11022:SF12 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN RECOGNITION PROTEIN 3 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;pattern recognition receptor activity#GO:0038187 defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;response to external stimulus#GO:0009605;defense response#GO:0006952 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014198.3|UniProtKB=G3RE68 G3RE68 RMI1 PTHR14790:SF15 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 RMI1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;sexual reproduction#GO:0019953;homologous recombination#GO:0035825;reproductive process#GO:0022414;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;resolution of meiotic recombination intermediates#GO:0000712;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;response to stimulus#GO:0050896;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;DNA helicase complex#GO:0033202 GORGO|Ensembl=ENSGGOG00000011315.3|UniProtKB=G3R6R5 G3R6R5 GRIK3 PTHR18966:SF174 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 3 gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic cation transmembrane transporter activity#GO:0008324;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;signaling receptor activity#GO:0038023;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;molecular transducer activity#GO:0060089;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;monoatomic cation channel activity#GO:0005261;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;sodium ion transmembrane transporter activity#GO:0015081 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987 asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA3#P01002;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>KA#P01026 GORGO|Ensembl=ENSGGOG00000027895.2|UniProtKB=G3SDA7 G3SDA7 LOC101139802 PTHR11461:SF186 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B4 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000000534.3|UniProtKB=G3QE41 G3QE41 ALG9 PTHR22760:SF2 GLYCOSYLTRANSFERASE ALPHA-1,2-MANNOSYLTRANSFERASE ALG9 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000023990.2|UniProtKB=G3RXF0 G3RXF0 SUOX PTHR19372:SF7 SULFITE REDUCTASE SULFITE OXIDASE, MITOCHONDRIAL intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;reductase#PC00198;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010730.3|UniProtKB=G3R588 G3R588 KLHL25 PTHR24410:SF10 HL07962P-RELATED KELCH-LIKE PROTEIN 25 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of lipid metabolic process#GO:0019216;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;protein metabolic process#GO:0019538;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000027564.2|UniProtKB=A0A2I2YZ48 A0A2I2YZ48 PTHR10802:SF9 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 40 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transmembrane protein transporter activity#GO:0008320 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585 membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000007876.3|UniProtKB=G3QXY2 G3QXY2 SOHLH1 PTHR46665:SF1 TRANSCRIPTION FACTOR BHLH041-RELATED-RELATED SPERMATOGENESIS- AND OOGENESIS-SPECIFIC BASIC HELIX-LOOP-HELIX-CONTAINING PROTEIN 1 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000042322.1|UniProtKB=A0A2I2ZL57 A0A2I2ZL57 RSRC1 PTHR31968:SF4 SERINE/ARGININE-RELATED PROTEIN 53 SERINE_ARGININE-RELATED PROTEIN 53 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000040600.1|UniProtKB=A0A2I2ZNZ5 A0A2I2ZNZ5 SLC31A1 PTHR12483:SF22 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS HIGH AFFINITY COPPER UPTAKE PROTEIN 1 transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;copper ion transmembrane transport#GO:0035434;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000023900.2|UniProtKB=G3SAD4 G3SAD4 DYNLRB1 PTHR10779:SF17 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 1 binding#GO:0005488;protein binding#GO:0005515 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000028527.2|UniProtKB=G3S718 G3S718 PTHR23333:SF30 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 2B ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;establishment of spindle localization#GO:0051293;positive regulation of cellular process#GO:0048522;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;protein metabolic process#GO:0019538;organelle localization#GO:0051640;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;primary metabolic process#GO:0044238;establishment of cell polarity#GO:0030010;modification-dependent protein catabolic process#GO:0019941;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular localization#GO:0051641;spindle localization#GO:0051653;establishment or maintenance of cell polarity#GO:0007163;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment of organelle localization#GO:0051656;regulation of cell cycle#GO:0051726;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cell cycle process#GO:0022402 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000005731.3|UniProtKB=G3QSH3 G3QSH3 SCRN1 PTHR12994:SF7 SECERNIN SECERNIN-1 GORGO|Ensembl=ENSGGOG00000001496.3|UniProtKB=G3QGL8 G3QGL8 NRP1 PTHR46806:SF4 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN NEUROPILIN-1 signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 neuron differentiation#GO:0030182;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neural crest cell migration#GO:0001755;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;vasculogenesis#GO:0001570;positive regulation of cellular component biogenesis#GO:0044089;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;vascular endothelial growth factor receptor signaling pathway#GO:0048010;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;response to stimulus#GO:0050896;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344;positive regulation of locomotion#GO:0040017;regulation of filopodium assembly#GO:0051489;neuron projection guidance#GO:0097485;mesenchyme development#GO:0060485;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon guidance#GO:0007411;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell projection organization#GO:0031346;stem cell development#GO:0048864;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;cell motility#GO:0048870;regulation of cellular process#GO:0050794;neural crest cell differentiation#GO:0014033;plasma membrane bounded cell projection morphogenesis#GO:0120039;mesenchymal cell differentiation#GO:0048762;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;animal organ development#GO:0048513;response to stress#GO:0006950;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;sprouting angiogenesis#GO:0002040;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;signaling#GO:0023052;circulatory system development#GO:0072359;cell projection organization#GO:0030030;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular developmental process#GO:0048869;axon development#GO:0061564;stem cell differentiation#GO:0048863;response to wounding#GO:0009611;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;plasma membrane bounded cell projection organization#GO:0120036;tube development#GO:0035295;neural crest cell development#GO:0014032;cell migration#GO:0016477;tissue development#GO:0009888;system development#GO:0048731;regulation of cell projection assembly#GO:0060491;regulation of cell motility#GO:2000145;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568 axon#GO:0030424;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165 Axon guidance mediated by semaphorins#P00007>Neuropilin 1#P00338 GORGO|Ensembl=ENSGGOG00000034844.2|UniProtKB=G3SKJ8 G3SKJ8 TMEM50B PTHR13180:SF0 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50B vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000024445.2|UniProtKB=G3S9S3 G3S9S3 LST1 PTHR15452:SF5 LEUKOCYTE-SPECIFIC TRANSCRIPT 1 PROTEIN LEUKOCYTE-SPECIFIC TRANSCRIPT 1 PROTEIN cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;dendrite development#GO:0016358;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005596.3|UniProtKB=G3QS53 G3QS53 PANX PTHR15759:SF5 PANNEXIN PANNEXIN-1 channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;transport#GO:0006810;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000011833.3|UniProtKB=G3R852 G3R852 PTHR14130:SF12 3BP-1 RELATED RHOGAP BARGIN-RELATED GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585 cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000016363.3|UniProtKB=G3RJS7 G3RJS7 TBC1D14 PTHR22957:SF367 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 14 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of autophagosome assembly#GO:2000785 recycling endosome#GO:0055037;autophagosome#GO:0005776;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000040432.1|UniProtKB=A0A2I2YXM8 A0A2I2YXM8 PIERCE2 PTHR20899:SF4 PIERCE HOMOLOG PIERCER OF MICROTUBULE WALL 2 PROTEIN GORGO|Ensembl=ENSGGOG00000009661.3|UniProtKB=G3R2I5 G3R2I5 THRA PTHR24082:SF42 NUCLEAR HORMONE RECEPTOR THYROID HORMONE RECEPTOR ALPHA RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;intracellular receptor signaling pathway#GO:0030522;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;negative regulation of DNA-templated transcription#GO:0045892;hormone-mediated signaling pathway#GO:0009755;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000008534.3|UniProtKB=A0A2I2ZB37 A0A2I2ZB37 MEF2D PTHR11945:SF23 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2D sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;CCKR signaling map#P06959>MEF2#P07032;CCKR signaling map#P06959>MEF2D#P07048 GORGO|Ensembl=ENSGGOG00000006157.3|UniProtKB=G3QTJ9 G3QTJ9 PDK3 PTHR11947:SF21 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 3, MITOCHONDRIAL protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of carbohydrate metabolic process#GO:0006109;regulation of lipid metabolic process#GO:0019216;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000037769.1|UniProtKB=A0A2I2ZRP7 A0A2I2ZRP7 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014316.3|UniProtKB=A0A2I2Z3X4 A0A2I2Z3X4 MYH11 PTHR45615:SF23 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-11 cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 GORGO|Ensembl=ENSGGOG00000011582.3|UniProtKB=G3SE25 G3SE25 PTHR24135:SF4 SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3 signaling receptor complex adaptor activity#GO:0030159;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 system process#GO:0003008;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;nervous system process#GO:0050877;cognition#GO:0050890;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cellular component organization#GO:0016043 plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;dendritic spine#GO:0043197;postsynaptic membrane#GO:0045211;dendrite#GO:0030425;dendritic tree#GO:0097447;postsynaptic density#GO:0014069 scaffold/adaptor protein#PC00226 Ionotropic glutamate receptor pathway#P00037>PSD95#P00999 GORGO|Ensembl=ENSGGOG00000005581.3|UniProtKB=A0A2I2Y6M8 A0A2I2Y6M8 MPHOSPH9 PTHR14926:SF1 M-PHASE PHOSPHOPROTEIN 9 M-PHASE PHOSPHOPROTEIN 9 microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000036497.1|UniProtKB=A0A2I2Y9L4 A0A2I2Y9L4 PTHR34755:SF2 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE_ARGININE REPETITIVE MATRIX PROTEIN 3 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 GORGO|Ensembl=ENSGGOG00000002473.3|UniProtKB=G3QJ52 G3QJ52 GINS1 PTHR12914:SF2 PARTNER OF SLD5 DNA REPLICATION COMPLEX GINS PROTEIN PSF1 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;mitotic DNA replication#GO:1902969;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic cell cycle#GO:0000278;DNA strand elongation involved in DNA replication#GO:0006271;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cell cycle process#GO:0022402;DNA-templated DNA replication#GO:0006261 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;CMG complex#GO:0071162;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;chromosome#GO:0005694;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000003822.3|UniProtKB=G3QML6 G3QML6 ACAA1 PTHR43853:SF8 3-KETOACYL-COA THIOLASE, PEROXISOMAL 3-KETOACYL-COA THIOLASE, PEROXISOMAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000000390.3|UniProtKB=G3QDQ8 G3QDQ8 UBAC1 PTHR46738:SF1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000014691.3|UniProtKB=G3RFI2 G3RFI2 DSCAM PTHR13817:SF68 TITIN CELL ADHESION MOLECULE DSCAM structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000002674.3|UniProtKB=G3QJN6 G3QJN6 COQ7 PTHR11237:SF6 COENZYME Q10 BIOSYNTHESIS PROTEIN 7 NADPH-DEPENDENT 3-DEMETHOXYUBIQUINONE 3-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 biological regulation#GO:0065007;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;regulation of reactive oxygen species metabolic process#GO:2000377;metabolic process#GO:0008152 cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000024198.2|UniProtKB=G3S6M3 G3S6M3 SCAMP4 PTHR10687:SF11 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 4 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000010514.3|UniProtKB=G3R4P3 G3R4P3 LYPD4 PTHR16529:SF6 CD177 ANTIGEN LY6_PLAUR DOMAIN-CONTAINING PROTEIN 4 plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;membrane raft#GO:0045121 GORGO|Ensembl=ENSGGOG00000012480.3|UniProtKB=A0A2I2ZR66 A0A2I2ZR66 DAP PTHR13177:SF3 DEATH-ASSOCIATED PROTEIN 1 DEATH-ASSOCIATED PROTEIN 1 ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 apoptotic process#GO:0006915;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;response to stimulus#GO:0050896;negative regulation of translation#GO:0017148;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of catabolic process#GO:0009895;cell communication#GO:0007154;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of autophagy#GO:0010507;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190 GORGO|Ensembl=ENSGGOG00000012695.3|UniProtKB=A0A2I2YWI9 A0A2I2YWI9 RASGRP2 PTHR23113:SF16 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 GORGO|Ensembl=ENSGGOG00000024092.2|UniProtKB=A0A2I2YXA7 A0A2I2YXA7 PTHR19051:SF35 KERATIN-ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 13-3 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000023856.2|UniProtKB=G3S559 G3S559 PTHR12555:SF18 UBIQUITIN FUSION DEGRADATON PROTEIN 1 UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1 binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;protein binding#GO:0005515 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 GORGO|Ensembl=ENSGGOG00000013743.3|UniProtKB=G3RD08 G3RD08 KCNA7 PTHR11537:SF155 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 7 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000013917.3|UniProtKB=G3RDG6 G3RDG6 STOX2 PTHR22437:SF2 WINGED HELIX DOMAIN-CONTAINING PROTEIN STORKHEAD-BOX PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000014994.3|UniProtKB=G3RG91 G3RG91 FAM229B PTHR35355:SF2 PROTEIN FAM229A PROTEIN FAM229B GORGO|Ensembl=ENSGGOG00000004407.3|UniProtKB=G3SGU5 G3SGU5 PTHR45712:SF5 AGAP008170-PA PODOCAN-LIKE PROTEIN 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005698.3|UniProtKB=G3QSE8 G3QSE8 SMYD2 PTHR12197:SF193 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD N-LYSINE METHYLTRANSFERASE SMYD2 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;circulatory system development#GO:0072359;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;heart development#GO:0007507;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;animal organ development#GO:0048513 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000041263.1|UniProtKB=A0A2I2ZDS4 A0A2I2ZDS4 IL21R PTHR23037:SF7 CYTOKINE RECEPTOR INTERLEUKIN-21 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003584.3|UniProtKB=G3S2X1 G3S2X1 NECAB3 PTHR12178:SF3 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 3 regulation of biosynthetic process#GO:0009889;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi cisterna#GO:0031985;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi cis cisterna#GO:0000137;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795 GORGO|Ensembl=ENSGGOG00000011922.3|UniProtKB=G3R8C8 G3R8C8 TRAM2 PTHR12371:SF4 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 2 cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000043416.1|UniProtKB=A0A2I2Z646 A0A2I2Z646 PTHR45732:SF8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP RIBOSYLATION FACTOR LIKE GTPASE 8B anterograde axonal transport#GO:0008089;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;axonal transport#GO:0098930;lysosomal transport#GO:0007041;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;endosomal transport#GO:0016197;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765 GORGO|Ensembl=ENSGGOG00000023400.2|UniProtKB=G3S8C1 G3S8C1 ODF1 PTHR17125:SF2 OUTER DENSE FIBER PROTEIN 1 OUTER DENSE FIBER PROTEIN 1 microtubule cytoskeleton#GO:0015630;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000038425.1|UniProtKB=A0A2I2Z162 A0A2I2Z162 PTHR12538:SF13 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000026275.2|UniProtKB=G3RXQ1 G3RXQ1 TMEM19 PTHR13353:SF5 TRANSMEMBRANE PROTEIN 19 TRANSMEMBRANE PROTEIN 19 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000016777.3|UniProtKB=G3RKT8 G3RKT8 GLCE PTHR13174:SF3 D-GLUCURONYL C5-EPIMERASE D-GLUCURONYL C5-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493 isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000025593.2|UniProtKB=G3RSQ9 G3RSQ9 FSCN1 PTHR10551:SF23 FASCIN FASCIN actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell migration#GO:0016477;cytoskeleton organization#GO:0007010;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell projection membrane#GO:0031253;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;filopodium#GO:0030175;axon#GO:0030424;intracellular organelle#GO:0043229;growth cone#GO:0030426;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;membraneless organelle#GO:0043228;ruffle#GO:0001726;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000009645.3|UniProtKB=G3R2G8 G3R2G8 CAVIN4 PTHR15240:SF4 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 4 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853;intracellular anatomical structure#GO:0005622;membrane raft#GO:0045121;membrane#GO:0016020;caveola#GO:0005901;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011671.3|UniProtKB=G3R7Q6 G3R7Q6 SPTBN2 PTHR11915:SF325 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 2 cytoskeletal protein binding#GO:0008092;structural molecule activity#GO:0005198;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;structural constituent of synapse#GO:0098918 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987 cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000015506.3|UniProtKB=G3RHK4 G3RHK4 TLCD3A PTHR13439:SF20 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 3A homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;chemical homeostasis#GO:0048878 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000039787.1|UniProtKB=A0A2I2YS46 A0A2I2YS46 STAG1 PTHR11199:SF6 STROMAL ANTIGEN COHESIN SUBUNIT SA-1 chromatin binding#GO:0003682;binding#GO:0005488 cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000011874.3|UniProtKB=G3R879 G3R879 FMOD PTHR45712:SF4 AGAP008170-PA FIBROMODULIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000042139.1|UniProtKB=A0A2I2Z4K8 A0A2I2Z4K8 CALML3 PTHR23050:SF557 CALCIUM BINDING PROTEIN CALMODULIN-LIKE PROTEIN 3 ion binding#GO:0043167;kinase activator activity#GO:0019209;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;molecular function activator activity#GO:0140677;cation binding#GO:0043169;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 detection of chemical stimulus#GO:0009593;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;calcineurin-mediated signaling#GO:0097720;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to calcium ion#GO:0051592;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;signal transduction#GO:0007165;detection of stimulus#GO:0051606;intracellular signaling cassette#GO:0141124;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;response to chemical#GO:0042221;regulation of monoatomic ion transport#GO:0043269;response to metal ion#GO:0010038;regulation of monoatomic cation transmembrane transport#GO:1904062;calcium-mediated signaling#GO:0019722;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of localization#GO:0032879;regulation of transport#GO:0051049 centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;myelin sheath#GO:0043209;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755 GORGO|Ensembl=ENSGGOG00000016540.3|UniProtKB=A0A2I2Y869 A0A2I2Y869 ENY2 PTHR12514:SF1 ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR TRANSCRIPTION AND MRNA EXPORT FACTOR ENY2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;regulation of gene expression#GO:0010468;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;localization#GO:0051179;nucleic acid transport#GO:0050657;regulation of DNA-templated transcription#GO:0006355;nuclear transport#GO:0051169;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;metabolic process#GO:0008152;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406 nucleus#GO:0005634;chromatin#GO:0000785;SAGA complex#GO:0000124;DUBm complex#GO:0071819;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004987.3|UniProtKB=G3QQL5 G3QQL5 GIPC2 PTHR12259:SF3 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC2 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010285.3|UniProtKB=G3R448 G3R448 DNAAF10 PTHR10971:SF2 MRNA EXPORT FACTOR AND BUB3 DYNEIN AXONEMAL ASSEMBLY FACTOR 10 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004956.3|UniProtKB=G3QQI9 G3QQI9 VPS37B PTHR13678:SF9 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37B protein localization to vacuole#GO:0072665;localization within membrane#GO:0051668;localization#GO:0051179;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;cellular localization#GO:0051641;protein transport#GO:0015031;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;metabolic process#GO:0008152;protein targeting to membrane#GO:0006612;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;establishment of protein localization to membrane#GO:0090150;protein targeting to vacuole#GO:0006623;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 vesicle membrane#GO:0012506;membrane#GO:0016020;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000012154.3|UniProtKB=A0A2I2ZWM1 A0A2I2ZWM1 DTL PTHR22852:SF2 LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN DENTICLELESS PROTEIN HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;primary metabolic process#GO:0044238;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;protein metabolic process#GO:0019538;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000025673.2|UniProtKB=G3SC07 G3SC07 CRISPLD1 PTHR10334:SF73 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN LCCL DOMAIN-CONTAINING 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000016783.3|UniProtKB=G3RKU4 G3RKU4 RDH16 PTHR43313:SF11 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 16 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 cellular process#GO:0009987;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;terpenoid metabolic process#GO:0006721;olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000016145.3|UniProtKB=G3RJ71 G3RJ71 NT5M PTHR16504:SF6 5'(3')-DEOXYRIBONUCLEOTIDASE 5'(3')-DEOXYRIBONUCLEOTIDASE, MITOCHONDRIAL phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 GORGO|Ensembl=ENSGGOG00000007328.3|UniProtKB=G3QWL4 G3QWL4 LOC101144727 PTHR12743:SF0 CYTOCHROME C1 HEME LYASE HOLOCYTOCHROME C-TYPE SYNTHASE catalytic activity#GO:0003824;carbon-sulfur lyase activity#GO:0016846;catalytic activity, acting on a protein#GO:0140096;lyase activity#GO:0016829 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 lyase#PC00144 GORGO|Ensembl=ENSGGOG00000023085.2|UniProtKB=G3RQZ0 G3RQZ0 UCP1 PTHR45618:SF19 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL BROWN FAT UNCOUPLING PROTEIN 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;temperature homeostasis#GO:0001659;intracellular transport#GO:0046907;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;multicellular organismal process#GO:0032501;mitochondrial transmembrane transport#GO:1990542;adaptive thermogenesis#GO:1990845;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;homeostatic process#GO:0042592;response to cold#GO:0009409;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000014469.3|UniProtKB=G3RZI1 G3RZI1 PLRG1 PTHR19923:SF0 WD40 REPEAT PROTEINPRL1/PRL2-RELATED PLEIOTROPIC REGULATOR 1 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 GORGO|Ensembl=ENSGGOG00000004057.3|UniProtKB=G3SFS3 G3SFS3 STRIP1 PTHR13239:SF7 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 STRIATIN-INTERACTING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014543.3|UniProtKB=G3RF27 G3RF27 FKBP14 PTHR46222:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP14 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000012694.3|UniProtKB=G3RAB7 G3RAB7 TGIF1 PTHR11850:SF425 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF1 double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>TGIF1#P06725 GORGO|Ensembl=ENSGGOG00000003267.2|UniProtKB=G3QL66 G3QL66 KCNB2 PTHR11537:SF134 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 2 transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 metal ion transport#GO:0030001;action potential#GO:0001508;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell body#GO:0044297;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;dendrite#GO:0030425;dendritic tree#GO:0097447;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000043887.1|UniProtKB=A0A2I2YML4 A0A2I2YML4 C1H1orf216 PTHR35673:SF1 UPF0500 PROTEIN C1ORF216 UPF0500 PROTEIN C1ORF216 GORGO|Ensembl=ENSGGOG00000023583.2|UniProtKB=G3RSQ0 G3RSQ0 LOC101150648 PTHR48018:SF116 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5B2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014277.3|UniProtKB=G3RED8 G3RED8 AKAP3 PTHR10226:SF9 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN 3 binding#GO:0005488;protein kinase A binding#GO:0051018;protein binding#GO:0005515 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;localization#GO:0051179;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;9+2 motile cilium#GO:0097729;cilium#GO:0005929;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;sperm principal piece#GO:0097228 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027425.2|UniProtKB=A0A2I2YV02 A0A2I2YV02 MAP4K3 PTHR48012:SF17 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCKR#P00311 GORGO|Ensembl=ENSGGOG00000016098.3|UniProtKB=A0A2I2ZEA0 A0A2I2ZEA0 PTHR24381:SF423 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 391 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000025995.2|UniProtKB=A0A2I2ZHH1 A0A2I2ZHH1 MTERF1 PTHR15437:SF2 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR 1, MITOCHONDRIAL sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488 gene expression#GO:0010467;mitochondrial transcription#GO:0006390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription termination#GO:0006353;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;nucleic acid biosynthetic process#GO:0141187 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389;General transcription regulation#P00023>TTF2#P00661 GORGO|Ensembl=ENSGGOG00000012520.3|UniProtKB=G3R9W8 G3R9W8 SHC3 PTHR10337:SF4 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;trans-synaptic signaling#GO:0099537;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Shc#P01175;FGF signaling pathway#P00021>Shc#P00639;EGF receptor signaling pathway#P00018>Shc#P00554 GORGO|Ensembl=ENSGGOG00000022763.2|UniProtKB=G3S872 G3S872 LOC101143671 PTHR13999:SF23 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN DISPANIN SUBFAMILY A MEMBER 2D-RELATED cell surface receptor signaling pathway#GO:0007166;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;response to type II interferon#GO:0034341;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to peptide#GO:1901652;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;response to virus#GO:0009615;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000004519.3|UniProtKB=G3RVT4 G3RVT4 LOC101130526 PTHR13946:SF47 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000007489.2|UniProtKB=G3QWZ5 G3QWZ5 SHISAL2B PTHR31395:SF2 SHISA PROTEIN SHISA-LIKE-2B scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000043508.1|UniProtKB=A0A2I2ZID2 A0A2I2ZID2 LOC101140958 PTHR26450:SF401 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52K1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005994.3|UniProtKB=A0A2I2YPY4 A0A2I2YPY4 RBM26 PTHR14398:SF2 RNA RECOGNITION RRM/RNP DOMAIN RNA-BINDING PROTEIN 26 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009060.3|UniProtKB=G3R112 G3R112 ALDH6A1 PTHR43866:SF3 MALONATE-SEMIALDEHYDE DEHYDROGENASE METHYLMALONATE-SEMIALDEHYDE_MALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carboxylic acid catabolic process#GO:0046395;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;nucleobase catabolic process#GO:0046113;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 Pyrimidine Metabolism#P02771>Methylmalonate Semialdehyde Dehydrogenase#P03124 GORGO|Ensembl=ENSGGOG00000010634.3|UniProtKB=G3R505 G3R505 LDHD PTHR11748:SF111 D-LACTATE DEHYDROGENASE D-LACTATE DEHYDROGENASE, MITOCHONDRIAL nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488 carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010545.3|UniProtKB=G3R4S5 G3R4S5 MTMR7 PTHR10807:SF35 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3-PHOSPHATE PHOSPHATASE MTMR7 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;dephosphorylation#GO:0016311;lipid modification#GO:0030258;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000012454.3|UniProtKB=G3S7J5 G3S7J5 LOC109024497 PTHR23262:SF233 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-12 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000003182.3|UniProtKB=G3QKY9 G3QKY9 RPS3A PTHR11830:SF28 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000003146.3|UniProtKB=G3QKW0 G3QKW0 SOAT2 PTHR10408:SF10 STEROL O-ACYLTRANSFERASE STEROL O-ACYLTRANSFERASE 2 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;sterol binding#GO:0032934;acyltransferase activity#GO:0016746;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;cholesterol binding#GO:0015485;lipid binding#GO:0008289;catalytic activity#GO:0003824;transferase activity#GO:0016740;heterocyclic compound binding#GO:1901363;steroid binding#GO:0005496;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;alcohol binding#GO:0043178 primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;cholesterol efflux#GO:0033344;cellular process#GO:0009987;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;steroid metabolic process#GO:0008202;lipid transport#GO:0006869;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;transport#GO:0006810;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sterol transport#GO:0015918;establishment of localization#GO:0051234;sterol metabolic process#GO:0016125 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transferase#PC00220;acyltransferase#PC00042 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 GORGO|Ensembl=ENSGGOG00000034944.2|UniProtKB=G3SKP4 G3SKP4 OPHN1 PTHR12552:SF2 OLIGOPHRENIN 1 OLIGOPHRENIN-1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 regulation of catabolic process#GO:0009894;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;synaptic vesicle recycling#GO:0036465;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;localization#GO:0051179;regulation of synaptic transmission, glutamatergic#GO:0051966;actin filament-based process#GO:0030029;modulation of chemical synaptic transmission#GO:0050804;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;synaptic vesicle endocytosis#GO:0048488;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;regulation of endocytosis#GO:0030100;cytoskeleton organization#GO:0007010;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein metabolic process#GO:0051246;cellular localization#GO:0051641;regulation of signaling#GO:0023051;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;endocytosis#GO:0006897;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043 cytoskeleton#GO:0005856;axon terminus#GO:0043679;membraneless organelle#GO:0043228;cell junction#GO:0030054;neuron projection#GO:0043005;presynapse#GO:0098793;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;dendritic tree#GO:0097447;axon#GO:0030424;intracellular organelle#GO:0043229;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;dendritic spine#GO:0043197;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;terminal bouton#GO:0043195;cell projection#GO:0042995;neuron projection terminus#GO:0044306;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000025290.2|UniProtKB=G3RPD2 G3RPD2 SNF8 PTHR12806:SF1 EAP30 SUBUNIT OF ELL COMPLEX VACUOLAR-SORTING PROTEIN SNF8 cellular localization#GO:0051641;protein transport#GO:0015031;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment of protein localization to vacuole#GO:0072666;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;endosomal transport#GO:0016197;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000010138.3|UniProtKB=G3R3R9 G3R3R9 TNC PTHR46708:SF1 TENASCIN TENASCIN anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;neuron projection development#GO:0031175;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000000701.3|UniProtKB=A0A2I2YJL3 A0A2I2YJL3 TDP1 PTHR12415:SF0 TYROSYL-DNA PHOSPHODIESTERASE 1 TYROSYL-DNA PHOSPHODIESTERASE 1 catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000002429.3|UniProtKB=G3QJ14 G3QJ14 CFHR5 PTHR45785:SF9 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H-RELATED PROTEIN 5 protein binding#GO:0005515;complement binding#GO:0001848;binding#GO:0005488 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;humoral immune response#GO:0006959;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;complement activation#GO:0006956;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;regulation of immune response#GO:0050776;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 complement component#PC00078 GORGO|Ensembl=ENSGGOG00000003205.3|UniProtKB=G3S1B0 G3S1B0 PTHR10371:SF3 NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954 mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 dehydrogenase#PC00092;oxidoreductase#PC00176 Parkinson disease#P00049>Complex I#P01237 GORGO|Ensembl=ENSGGOG00000013924.3|UniProtKB=G3RDH2 G3RDH2 MTNR1B PTHR24228:SF54 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN RECEPTOR TYPE 1B transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;regulation of protein secretion#GO:0050708;cell communication#GO:0007154;regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of insulin secretion#GO:0050796;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of localization#GO:0032879;regulation of transport#GO:0051049 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000005726.3|UniProtKB=G3QSH8 G3QSH8 CCDC88C PTHR18947:SF31 HOOK PROTEINS PROTEIN DAPLE protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 microtubule-based process#GO:0007017;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;cytoskeleton organization#GO:0007010;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cytoplasmic microtubule organization#GO:0031122;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011786.3|UniProtKB=G3R7Z9 G3R7Z9 AFF4 PTHR10528:SF15 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 4 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;system process#GO:0003008;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;nucleic acid biosynthetic process#GO:0141187;nervous system process#GO:0050877 intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000014882.3|UniProtKB=G3RFZ6 G3RFZ6 QARS1 PTHR43097:SF16 GLUTAMINE-TRNA LIGASE GLUTAMINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467 catalytic complex#GO:1902494;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 GORGO|Ensembl=ENSGGOG00000004197.4|UniProtKB=G3QNK0 G3QNK0 PCLO PTHR14113:SF6 PICCOLO/BASSOON PROTEIN PICCOLO structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;protein localization to cell junction#GO:1902414;synapse organization#GO:0050808;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component organization or biogenesis#GO:0071840;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;intracellular protein localization#GO:0008104;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cellular process#GO:0009987 cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;plasma membrane bounded cell projection#GO:0120025;GABA-ergic synapse#GO:0098982;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;glutamatergic synapse#GO:0098978;cytoskeleton#GO:0005856;presynaptic active zone#GO:0048786;membraneless organelle#GO:0043228;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000001191.3|UniProtKB=G3QFU5 G3QFU5 MIA PTHR47312:SF1 MELANOMA-DERIVED GROWTH REGULATORY PROTEIN MELANOMA-DERIVED GROWTH REGULATORY PROTEIN cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 GORGO|Ensembl=ENSGGOG00000015179.3|UniProtKB=A0A2I2YN38 A0A2I2YN38 CHAT PTHR22589:SF14 CARNITINE O-ACYLTRANSFERASE CHOLINE O-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407 signaling#GO:0023052;biosynthetic process#GO:0009058;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;anterograde trans-synaptic signaling#GO:0098916;cellular process#GO:0009987;regulation of biological process#GO:0050789;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;neuromuscular synaptic transmission#GO:0007274;trans-synaptic signaling#GO:0099537;metabolic process#GO:0008152 cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 GORGO|Ensembl=ENSGGOG00000010887.3|UniProtKB=A0A2I2ZEW3 A0A2I2ZEW3 SNAPC4 PTHR46621:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 snRNA transcription#GO:0009301;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase III#GO:0042796;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 GORGO|Ensembl=ENSGGOG00000015315.3|UniProtKB=G3RH25 G3RH25 TMEM88 PTHR28628:SF3 TRANSMEMBRANE PROTEIN 88-RELATED TRANSMEMBRANE PROTEIN 88 regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000013932.3|UniProtKB=A0A2I2YCL9 A0A2I2YCL9 BTD PTHR10609:SF14 BIOTINIDASE-RELATED BIOTINIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;monocarboxylic acid metabolic process#GO:0032787;biotin metabolic process#GO:0006768;cellular process#GO:0009987 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000013802.3|UniProtKB=G3RD66 G3RD66 PLEKHH3 PTHR46049:SF5 AGAP003327-PA PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000015378.3|UniProtKB=G3RH85 G3RH85 CTSK PTHR12411:SF1048 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN K catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000007220.3|UniProtKB=A0A2I2YQY6 A0A2I2YQY6 NPM1 PTHR22747:SF28 NUCLEOPLASMIN NUCLEOPHOSMIN nucleic acid binding#GO:0003676;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682;RNA binding#GO:0003723;protein binding#GO:0005515 ribosomal small subunit biogenesis#GO:0042274;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;regulation of cell cycle process#GO:0010564;positive regulation of macromolecule metabolic process#GO:0010604;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular localization#GO:0051641;ribosomal large subunit export from nucleus#GO:0000055;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cell cycle#GO:0051726;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;establishment of organelle localization#GO:0051656;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;regulation of gene expression#GO:0010468;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640;nuclear transport#GO:0051169;nuclear export#GO:0051168;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000011789.3|UniProtKB=G3R7Z6 G3R7Z6 F2RL2 PTHR24232:SF0 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 3 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Blood coagulation#P00011>mPAR-3#P00452 GORGO|Ensembl=ENSGGOG00000012635.3|UniProtKB=G3RA63 G3RA63 PELO PTHR10853:SF11 PELOTA PROTEIN PELOTA HOMOLOG molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;translational elongation#GO:0006414;metabolic process#GO:0008152;gene expression#GO:0010467;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;organelle organization#GO:0006996;cellular process#GO:0009987;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;RNA catabolic process#GO:0006401;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;rescue of stalled cytosolic ribosome#GO:0072344;regulation of biological process#GO:0050789;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;protein metabolic process#GO:0019538;translation#GO:0006412;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 translation release factor#PC00225 GORGO|Ensembl=ENSGGOG00000010562.3|UniProtKB=G3R4T6 G3R4T6 BID PTHR35447:SF1 BH3-INTERACTING DOMAIN DEATH AGONIST BH3-INTERACTING DOMAIN DEATH AGONIST mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of cellular component organization#GO:0051128;positive regulation of programmed cell death#GO:0043068;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of organelle organization#GO:0033043;positive regulation of signaling#GO:0023056;positive regulation of organelle organization#GO:0010638;regulation of release of cytochrome c from mitochondria#GO:0090199;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;programmed cell death#GO:0012501;regulation of mitochondrion organization#GO:0010821;cell death#GO:0008219;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of apoptotic signaling pathway#GO:2001233 mitochondrion#GO:0005739;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000026762.2|UniProtKB=G3SJ01 G3SJ01 PTHR11722:SF5 60S RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN EL13 binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025532.2|UniProtKB=G3S2H5 G3S2H5 LCE1B PTHR48615:SF1 LATE CORNIFIED ENVELOPE PROTEIN 1C LATE CORNIFIED ENVELOPE PROTEIN 1B GORGO|Ensembl=ENSGGOG00000006400.3|UniProtKB=G3QU60 G3QU60 LOC101152908 PTHR24242:SF216 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 9A4 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016090.3|UniProtKB=A0A2I2Y4Y4 A0A2I2Y4Y4 TSSK4 PTHR24343:SF345 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 4 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000025919.2|UniProtKB=A0A2I2Z470 A0A2I2Z470 PTHR23236:SF64 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H POLYADENYLATE-BINDING PROTEIN 2 poly(A) binding#GO:0008143;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000017149.3|UniProtKB=A0A2I2ZE61 A0A2I2ZE61 RANBP10 PTHR12864:SF19 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEIN 10 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;guanyl-nucleotide exchange factor activity#GO:0005085 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;catabolic process#GO:0009056 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007758.3|UniProtKB=G3QXP0 G3QXP0 TNFRSF8 PTHR47497:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 8 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 8 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008450.3|UniProtKB=G3RX20 G3RX20 CANX PTHR11073:SF11 CALRETICULIN AND CALNEXIN CALNEXIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;response to chemical#GO:0042221;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein folding#GO:0006457;response to stimulus#GO:0050896;catabolic process#GO:0009056 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000008020.3|UniProtKB=G3QYB8 G3QYB8 CLPTM1 PTHR21347:SF14 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1-RELATED membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000612.3|UniProtKB=G3QEB1 G3QEB1 GPR171 PTHR24233:SF4 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 171 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000012701.3|UniProtKB=G3RAB8 G3RAB8 GPR146 PTHR24226:SF3 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 G PROTEIN-COUPLED RECEPTOR 146 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000000959.3|UniProtKB=G3QF80 G3QF80 SNAI2 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001648.3|UniProtKB=G3QH06 G3QH06 RALB PTHR24070:SF199 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-B GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 Ras Pathway#P04393>Ral#P04550 GORGO|Ensembl=ENSGGOG00000003012.3|UniProtKB=G3S3D5 G3S3D5 GPRC5C PTHR14511:SF15 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G PROTEIN-COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER C enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 membrane#GO:0016020;cell periphery#GO:0071944;vesicle#GO:0031982;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007577.3|UniProtKB=G3QX78 G3QX78 LOC101149550 PTHR26453:SF697 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6N1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010309.3|UniProtKB=G3RTU7 G3RTU7 HPS5 PTHR23287:SF18 RUBY-EYE2-LIKE PROTEIN BLOC-2 COMPLEX MEMBER HPS5 developmental pigmentation#GO:0048066;pigmentation#GO:0043473 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008602.3|UniProtKB=G3S967 G3S967 MCM8 PTHR11630:SF107 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM8 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000001148.3|UniProtKB=G3QFQ1 G3QFQ1 CRACD PTHR47574:SF3 CANCER-RELATED REGULATOR OF ACTIN DYNAMICS CAPPING PROTEIN-INHIBITING REGULATOR OF ACTIN DYNAMICS negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;multicellular organismal-level homeostasis#GO:0048871;regulation of protein depolymerization#GO:1901879;system process#GO:0003008;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;digestion#GO:0007586;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;tissue homeostasis#GO:0001894;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;regulation of actin filament depolymerization#GO:0030834;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein-containing complex disassembly#GO:0043244;regulation of actin cytoskeleton organization#GO:0032956;epithelial structure maintenance#GO:0010669;anatomical structure homeostasis#GO:0060249;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128 GORGO|Ensembl=ENSGGOG00000043209.1|UniProtKB=A0A2I2Y2L2 A0A2I2Y2L2 PTHR23267:SF518 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-29 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000006752.3|UniProtKB=G3QV42 G3QV42 LOC101144541 PTHR16932:SF2 INTERFERON ALPHA-INDUCIBLE PROTEIN 27 INTERFERON ALPHA-INDUCIBLE PROTEIN 27, MITOCHONDRIAL intracellular signal transduction#GO:0035556;cell communication#GO:0007154;apoptotic signaling pathway#GO:0097190;intrinsic apoptotic signaling pathway#GO:0097193;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cell death#GO:0008219;programmed cell death#GO:0012501;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000039401.1|UniProtKB=A0A2I2Y835 A0A2I2Y835 PTHR23236:SF42 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4B binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000027487.2|UniProtKB=G3SD25 G3SD25 PCNX4 PTHR12372:SF6 PECANEX PECANEX-LIKE PROTEIN 4 GORGO|Ensembl=ENSGGOG00000011880.3|UniProtKB=G3S289 G3S289 AMBRA1 PTHR22874:SF1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macroautophagy#GO:0016236;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000039071.1|UniProtKB=A0A2I2YKS2 A0A2I2YKS2 DEDD PTHR15205:SF2 DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;apoptotic signaling pathway#GO:0097190;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625 membraneless organelle#GO:0043228;nucleus#GO:0005634;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 GORGO|Ensembl=ENSGGOG00000001038.3|UniProtKB=G3S9R3 G3S9R3 NUP42 PTHR46527:SF1 NUCLEOPORIN-LIKE PROTEIN 2 NUCLEOPORIN NUP42 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000039134.1|UniProtKB=A0A2I2ZCG8 A0A2I2ZCG8 PTHR19339:SF2 T CELL RECEPTOR ALPHA VARIABLE 39 T CELL RECEPTOR ALPHA VARIABLE 22 GORGO|Ensembl=ENSGGOG00000022730.2|UniProtKB=G3RPB4 G3RPB4 CLEC4A PTHR22802:SF426 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER A binding#GO:0005488;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;defense response to fungus#GO:0050832;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006173.3|UniProtKB=G3QTL0 G3QTL0 ZNF264 PTHR24384:SF99 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 264 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000003327.3|UniProtKB=G3QLC3 G3QLC3 HID1 PTHR21575:SF12 PROTEIN HID1 PROTEIN HID1 cellular process#GO:0009987;Golgi organization#GO:0007030;anatomical structure maturation#GO:0071695;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;developmental maturation#GO:0021700;developmental process#GO:0032502;vesicle organization#GO:0016050;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi cisterna#GO:0031985;Golgi stack#GO:0005795;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000001556.3|UniProtKB=G3QGS1 G3QGS1 KCNG4 PTHR11537:SF167 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNG4 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;action potential#GO:0001508;metal ion transport#GO:0030001 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000026540.2|UniProtKB=G3S4K9 G3S4K9 LOC101153544 PTHR24103:SF661 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 49D ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;immune response#GO:0006955;defense response to symbiont#GO:0140546;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of biological process#GO:0050789;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000037101.1|UniProtKB=A0A2I2YAF1 A0A2I2YAF1 LOC101144365 PTHR11406:SF14 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE 1 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;kinase activity#GO:0016301;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;phosphoglycerate kinase activity#GO:0004618 ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate biosynthetic process#GO:0016051;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;monocarboxylic acid metabolic process#GO:0032787;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;pyruvate metabolic process#GO:0006090;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;ATP metabolic process#GO:0046034;oxoacid metabolic process#GO:0043436;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 GORGO|Ensembl=ENSGGOG00000005594.3|UniProtKB=G3SJR7 G3SJR7 FANK1 PTHR24183:SF1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000022595.2|UniProtKB=G3S7G3 G3S7G3 OCM PTHR11653:SF4 PARVALBUMIN ALPHA ONCOMODULIN-2 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000025525.2|UniProtKB=G3RUP4 G3RUP4 LOC101133829 PTHR26453:SF205 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10S1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026270.2|UniProtKB=G3RX27 G3RX27 TIPARP PTHR45740:SF7 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE TIPARP catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000013752.3|UniProtKB=A0A2I2ZS19 A0A2I2ZS19 ZMYND8 PTHR46453:SF3 PROTEIN KINASE C-BINDING PROTEIN 1 MYND-TYPE ZINC FINGER-CONTAINING CHROMATIN READER ZMYND8 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006655.3|UniProtKB=G3QUV4 G3QUV4 PPP2R1A PTHR10648:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 65 KDA REGULATORY SUBUNIT A ALPHA ISOFORM structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;microtubule cytoskeleton organization#GO:0000226;sister chromatid cohesion#GO:0007062;organelle assembly#GO:0070925 protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 GORGO|Ensembl=ENSGGOG00000012438.3|UniProtKB=G3S161 G3S161 LOC101152080 PTHR24289:SF13 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 17-ALPHA-HYDROXYLASE_17,20 LYASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;hormone biosynthetic process#GO:0042446;biological regulation#GO:0065007;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of biological quality#GO:0065008 GORGO|Ensembl=ENSGGOG00000025976.2|UniProtKB=G3SBB4 G3SBB4 PTHR11449:SF1 RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN EL30 RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007882.3|UniProtKB=G3QXY9 G3QXY9 SERPINA6 PTHR11461:SF34 SERINE PROTEASE INHIBITOR, SERPIN CORTICOSTEROID-BINDING GLOBULIN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000000755.3|UniProtKB=G3QEP5 G3QEP5 PTHR11193:SF8 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytoplasm#GO:0005737;U2 snRNP#GO:0005686;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000038781.1|UniProtKB=A0A2I2YU48 A0A2I2YU48 SNX22 PTHR15813:SF8 SORTING NEXIN-22 AND 24 SORTING NEXIN-22 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002320.3|UniProtKB=G3RQU7 G3RQU7 RNF5 PTHR12313:SF4 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF5 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;regulation of organelle assembly#GO:1902115;response to stress#GO:0006950;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;regulation of autophagosome assembly#GO:2000785;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000042821.1|UniProtKB=G3QI10 G3QI10 OR13C2 PTHR26453:SF616 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000022508.2|UniProtKB=G3S7T2 G3S7T2 LOC109027078 PTHR24381:SF430 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 454 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000042157.1|UniProtKB=A0A2I2YY17 A0A2I2YY17 PTHR13361:SF1 WW DOMAIN-BINDING PROTEIN 11 WW DOMAIN-BINDING PROTEIN 11 molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 RNA splicing#GO:0008380;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467 GORGO|Ensembl=ENSGGOG00000013396.3|UniProtKB=G3RC43 G3RC43 RTP3 PTHR14402:SF9 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 3 G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 detection of stimulus#GO:0051606;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;detection of stimulus involved in sensory perception#GO:0050906;establishment of protein localization#GO:0045184;cellular process#GO:0009987;response to chemical#GO:0042221;protein insertion into membrane#GO:0051205;multicellular organismal process#GO:0032501;membrane organization#GO:0061024;protein targeting to membrane#GO:0006612;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;cellular component organization or biogenesis#GO:0071840;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;establishment of localization#GO:0051234;system process#GO:0003008;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;protein targeting#GO:0006605;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;localization within membrane#GO:0051668;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;localization#GO:0051179;cellular localization#GO:0051641 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000014721.3|UniProtKB=G3RFK1 G3RFK1 RABL6 PTHR14932:SF1 RAS GTPASE-RELATED RAB-LIKE PROTEIN 6 guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000010095.3|UniProtKB=G3R3M1 G3R3M1 GNAT3 PTHR10218:SF66 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-3 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;cilium#GO:0005929;photoreceptor inner segment#GO:0001917;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750 heterotrimeric G-protein#PC00117;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000036219.1|UniProtKB=A0A2I2YKD3 A0A2I2YKD3 C9H11orf97 PTHR38326:SF1 CHROMOSOME 11 OPEN READING FRAME 97 CHROMOSOME 11 OPEN READING FRAME 97 GORGO|Ensembl=ENSGGOG00000023653.2|UniProtKB=A0A2I2ZK15 A0A2I2ZK15 PTHR11759:SF30 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;translation#GO:0006412;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001270.3|UniProtKB=G3QG04 G3QG04 UBIAD1 PTHR13929:SF17 1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE UBIA PRENYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;vitamin K metabolic process#GO:0042373;ketone metabolic process#GO:0042180;menaquinone biosynthetic process#GO:0009234;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000016275.3|UniProtKB=G3S218 G3S218 PTHR11474:SF4 TYROSINASE FAMILY MEMBER L-DOPACHROME TAUTOMERASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 pigment metabolic process#GO:0042440;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;brain development#GO:0007420;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;biological regulation#GO:0065007;developmental process#GO:0032502;pigment biosynthetic process#GO:0046148;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;cellular developmental process#GO:0048869;secondary metabolic process#GO:0019748;neurogenesis#GO:0022008;regulation of neurogenesis#GO:0050767;cell division#GO:0051301;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;pigmentation#GO:0043473;cell population proliferation#GO:0008283;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;system development#GO:0048731;phenol-containing compound biosynthetic process#GO:0046189;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;developmental pigmentation#GO:0048066;regulation of multicellular organismal process#GO:0051239;head development#GO:0060322;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;metabolic process#GO:0008152;secondary metabolite biosynthetic process#GO:0044550;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of cell population proliferation#GO:0008284;phenol-containing compound metabolic process#GO:0018958;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nervous system development#GO:0051962;central nervous system development#GO:0007417;cell differentiation#GO:0030154;forebrain development#GO:0030900;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;melanin biosynthetic process#GO:0042438 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;melanosome#GO:0042470;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000003445.3|UniProtKB=G3QLN0 G3QLN0 P2RX4 PTHR10125:SF18 P2X PURINOCEPTOR P2X PURINOCEPTOR 4 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000006985.3|UniProtKB=G3QVQ5 G3QVQ5 PSD PTHR10663:SF334 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 1 cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;ruffle#GO:0001726 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000002338.3|UniProtKB=A0A2I2Y929 A0A2I2Y929 CIRBP PTHR48034:SF5 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED COLD-INDUCIBLE RNA-BINDING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000023430.2|UniProtKB=A0A2I2Z5L2 A0A2I2Z5L2 IL32 PTHR48490:SF1 INTERLEUKIN-32 INTERLEUKIN-32 GORGO|Ensembl=ENSGGOG00000012888.3|UniProtKB=G3QPX5 G3QPX5 PTHR12928:SF4 FRG1 PROTEIN FRG1 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;catalytic step 2 spliceosome#GO:0071013;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000001875.3|UniProtKB=G3QHL8 G3QHL8 PPP1R12C PTHR24179:SF27 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12C enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme inhibitor activity#GO:0004857 neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000015930.3|UniProtKB=G3RIM4 G3RIM4 SPATA25 PTHR36857:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 25 SPERMATOGENESIS-ASSOCIATED PROTEIN 25 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproductive process#GO:0022414;sexual reproduction#GO:0019953;developmental process#GO:0032502;spermatogenesis#GO:0007283;multicellular organismal reproductive process#GO:0048609 GORGO|Ensembl=ENSGGOG00000009335.3|UniProtKB=G3R1P5 G3R1P5 MTPAP PTHR12271:SF133 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA processing#GO:0006397;RNA destabilization#GO:0050779;RNA processing#GO:0006396;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of mRNA metabolic process#GO:1903313;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000028169.2|UniProtKB=G3S949 G3S949 LRG1 PTHR45617:SF101 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH ALPHA-2-GLYCOPROTEIN signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein binding#GO:0005515 positive regulation of response to stimulus#GO:0048584;epithelium development#GO:0060429;tissue development#GO:0009888;cell migration#GO:0016477;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;response to wounding#GO:0009611;positive regulation of cellular process#GO:0048522;regulation of vasculature development#GO:1901342;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of response to stimulus#GO:0048583;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of anatomical structure morphogenesis#GO:0022603;morphogenesis of an epithelium#GO:0002009;response to stimulus#GO:0050896;positive regulation of angiogenesis#GO:0045766;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;positive regulation of signaling#GO:0023056;wound healing#GO:0042060;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026842.2|UniProtKB=G3S1F3 G3S1F3 EXOC8 PTHR21426:SF12 EXOCYST COMPLEX COMPONENT 8 EXOCYST COMPLEX COMPONENT 8 macromolecule localization#GO:0033036;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;post-Golgi vesicle-mediated transport#GO:0006892 cell periphery#GO:0071944;cell cortex#GO:0005938;cytoplasm#GO:0005737;exocyst#GO:0000145;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 GORGO|Ensembl=ENSGGOG00000016066.3|UniProtKB=G3RJ02 G3RJ02 DIPK1C PTHR21093:SF2 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1C GORGO|Ensembl=ENSGGOG00000011541.3|UniProtKB=G3R7C2 G3R7C2 CALCOCO1 PTHR31915:SF5 SKICH DOMAIN-CONTAINING PROTEIN CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 GORGO|Ensembl=ENSGGOG00000003323.3|UniProtKB=G3QLB9 G3QLB9 PKD2 PTHR10877:SF114 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2 potassium ion transmembrane transporter activity#GO:0015079;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;cation binding#GO:0043169;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;ion binding#GO:0043167;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;sodium channel activity#GO:0005272;metal ion binding#GO:0046872;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;gated channel activity#GO:0022836;calcium ion binding#GO:0005509;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215 detection of mechanical stimulus#GO:0050982;transport#GO:0006810;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;response to external stimulus#GO:0009605;calcium ion transport#GO:0006816;detection of stimulus#GO:0051606;response to mechanical stimulus#GO:0009612;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000002482.3|UniProtKB=A0A2I2ZXA2 A0A2I2ZXA2 LNPEP PTHR11533:SF42 PROTEASE M1 ZINC METALLOPROTEASE LEUCYL-CYSTINYL AMINOPEPTIDASE exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;cellular process#GO:0009987;peptide catabolic process#GO:0043171;regulation of blood pressure#GO:0008217;system process#GO:0003008;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;circulatory system process#GO:0003013;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000003836.3|UniProtKB=A0A2I2YJN6 A0A2I2YJN6 MOSPD1 PTHR34441:SF2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000011283.3|UniProtKB=A0A2I2ZYL1 A0A2I2ZYL1 PRKAG1 PTHR13780:SF38 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1 purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;binding#GO:0005488;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169 response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of carbohydrate biosynthetic process#GO:0043255;cellular response to stress#GO:0033554;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;response to nutrient levels#GO:0031667;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular response to glucose starvation#GO:0042149;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of carbohydrate metabolic process#GO:0006109;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 GORGO|Ensembl=ENSGGOG00000014865.3|UniProtKB=G3RFX7 G3RFX7 ADAMTS16 PTHR13723:SF140 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 16 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000012698.3|UniProtKB=G3RAC1 G3RAC1 TNNI1 PTHR13738:SF9 TROPONIN I TROPONIN I, SLOW SKELETAL MUSCLE cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 circulatory system process#GO:0003013;cardiac muscle contraction#GO:0060048;muscle contraction#GO:0006936;neuromuscular process#GO:0050905;nervous system process#GO:0050877;heart contraction#GO:0060047;system process#GO:0003008;muscle system process#GO:0003012;heart process#GO:0003015;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;striated muscle contraction#GO:0006941;skeletal muscle contraction#GO:0003009 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000010243.3|UniProtKB=G3R414 G3R414 PLCH2 PTHR10336:SF166 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ETA-2 phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity#GO:0016787;lipase activity#GO:0016298 regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell-cell signaling#GO:0007267;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794 metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000008306.3|UniProtKB=G3QZ31 G3QZ31 MYO1H PTHR13140:SF353 MYOSIN UNCONVENTIONAL MYOSIN-IH polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based movement#GO:0030048;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;transport#GO:0006810 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000014978.3|UniProtKB=A0A2I2YPN9 A0A2I2YPN9 LOC101130871 PTHR40712:SF3 FAMILY WITH SEQUENCE SIMILARITY 153 MEMBER C-RELATED SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000014115.3|UniProtKB=G3RE04 G3RE04 PTHR14947:SF26 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 781 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000028174.2|UniProtKB=G3RZ85 G3RZ85 KLHL24 PTHR24412:SF215 KELCH PROTEIN KELCH-LIKE PROTEIN 24 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008524.3|UniProtKB=G3QZL9 G3QZL9 TNFRSF4 PTHR47881:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 4 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;death receptor activity#GO:0005035;transmembrane signaling receptor activity#GO:0004888 response to stress#GO:0006950;inflammatory response#GO:0006954;response to stimulus#GO:0050896;defense response#GO:0006952 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026372.2|UniProtKB=G3S476 G3S476 PTHR14948:SF18 NG5 PROLINE RICH TRANSMEMBRANE PROTEIN 1B cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012821.3|UniProtKB=G3RAP9 G3RAP9 KDR PTHR24416:SF45 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;regulation of angiogenesis#GO:0045765;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;epithelium development#GO:0060429;cell migration#GO:0016477;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;tube development#GO:0035295;regulation of locomotion#GO:0040012;regulation of vasculature development#GO:1901342;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;endothelial cell differentiation#GO:0045446;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;positive regulation of angiogenesis#GO:0045766;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;cell differentiation#GO:0030154;circulatory system development#GO:0072359;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;angiogenesis#GO:0001525;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 GORGO|Ensembl=ENSGGOG00000023246.2|UniProtKB=A0A2I2ZPG5 A0A2I2ZPG5 PTHR47222:SF3 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 532 GORGO|Ensembl=ENSGGOG00000040077.1|UniProtKB=A0A2I2YE66 A0A2I2YE66 PTHR11822:SF31 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP] purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide metabolic process#GO:0009117 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;microbody#GO:0042579;peroxisome#GO:0005777;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016910.3|UniProtKB=G3S9X6 G3S9X6 MOG PTHR24100:SF71 BUTYROPHILIN MYELIN-OLIGODENDROCYTE GLYCOPROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000014603.3|UniProtKB=G3RF89 G3RF89 MAP3K1 PTHR24361:SF414 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Apoptosis signaling pathway#P00006>MEKK1#P00291;T cell activation#P00053>MEKK#P01297;FGF signaling pathway#P00021>MEKK1-5#P00634;Toll receptor signaling pathway#P00054>MEKK1#P01357;Integrin signalling pathway#P00034>ERK#P00907;Angiogenesis#P00005>MEKK1#P00208;Ras Pathway#P04393>MEKK1/4#P04543;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 GORGO|Ensembl=ENSGGOG00000003546.3|UniProtKB=G3QLW4 G3QLW4 DMAP1 PTHR12855:SF10 DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;H4 histone acetyltransferase complex#GO:1902562;nuclear chromosome#GO:0000228;intracellular organelle lumen#GO:0070013;protein acetyltransferase complex#GO:0031248;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000024399.2|UniProtKB=A0A2I2YXZ3 A0A2I2YXZ3 LUC7L3 PTHR12375:SF47 RNA-BINDING PROTEIN LUC7-RELATED LUC7-LIKE PROTEIN 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304 spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U2-type prespliceosome#GO:0071004;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000036189.1|UniProtKB=G3RGR8 G3RGR8 OR2J2 PTHR26453:SF318 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2J2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012512.3|UniProtKB=A0A2I2ZP70 A0A2I2ZP70 PTHR24210:SF13 LIM DOMAIN-CONTAINING PROTEIN LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1 cell adhesion#GO:0007155;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell junction organization#GO:0034330;regulation of cell communication#GO:0010646;cell-cell junction organization#GO:0045216;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;cell-cell adhesion#GO:0098609;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 GORGO|Ensembl=ENSGGOG00000039340.1|UniProtKB=A0A2I2ZP77 A0A2I2ZP77 PTHR23266:SF270 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-58 antigen binding#GO:0003823;binding#GO:0005488 immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000001286.3|UniProtKB=G3SGA7 G3SGA7 BCAS1 PTHR15016:SF6 BREAST CARCINOMA-AMPLIFIED SEQUENCE 1 BREAST CARCINOMA-AMPLIFIED SEQUENCE 1 nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;myelination#GO:0042552;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 GORGO|Ensembl=ENSGGOG00000012351.3|UniProtKB=A0A2I2ZGX1 A0A2I2ZGX1 RRAD PTHR45775:SF3 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN RAD binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;calcium channel regulator activity#GO:0005246;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000038013.1|UniProtKB=A0A2I2YLA0 A0A2I2YLA0 TENT5C PTHR12974:SF34 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5C catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000000318.3|UniProtKB=A0A2I2ZFR6 A0A2I2ZFR6 GTF2F1 PTHR13011:SF0 TFIIF-ALPHA GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1 enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488;transcription factor binding#GO:0008134;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIFalpha#P00663;Transcription regulation by bZIP transcription factor#P00055>TFIIFalpha#P01391 GORGO|Ensembl=ENSGGOG00000039675.1|UniProtKB=A0A2I2ZAU6 A0A2I2ZAU6 PTHR23236:SF16 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H POLYADENYLATE-BINDING PROTEIN 2 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000011661.3|UniProtKB=G3SB27 G3SB27 ZNF878 PTHR24379:SF109 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 878 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000008773.3|UniProtKB=A0A2I2ZXX5 A0A2I2ZXX5 IGSF1 PTHR11738:SF163 MHC CLASS I NK CELL RECEPTOR IMMUNOGLOBULIN SUPERFAMILY MEMBER 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000008189.3|UniProtKB=G3QYR6 G3QYR6 MPND PTHR10410:SF41 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED MPN DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000013907.3|UniProtKB=G3RDG9 G3RDG9 TBC1D15 PTHR22957:SF300 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 15 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000013123.3|UniProtKB=G3RBG1 G3RBG1 CHD6 PTHR45623:SF8 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD6 ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA binding#GO:0003677;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;histone binding#GO:0042393 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000003579.4|UniProtKB=G3QLZ8 G3QLZ8 ADAMTS3 PTHR13723:SF158 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 3 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000016038.3|UniProtKB=G3RIY6 G3RIY6 CDHR2 PTHR24026:SF133 FAT ATYPICAL CADHERIN-RELATED CADHERIN-RELATED FAMILY MEMBER 2 system development#GO:0048731;anatomical structure development#GO:0048856;plasma membrane bounded cell projection organization#GO:0120036;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;multicellular organismal process#GO:0032501;axon development#GO:0061564;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039 cell-cell junction#GO:0005911;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000008081.3|UniProtKB=G3QYG4 G3QYG4 C18H16orf78 PTHR35679:SF1 RIKEN CDNA 4933402J07 GENE RIKEN CDNA 4933402J07 GENE GORGO|Ensembl=ENSGGOG00000013121.3|UniProtKB=G3RQV2 G3RQV2 EMILIN3 PTHR15427:SF2 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-3 supramolecular fiber#GO:0099512;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein complex involved in cell adhesion#GO:0098636 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001187.3|UniProtKB=G3QFU1 G3QFU1 FBXL4 PTHR13318:SF152 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 4 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000010850.3|UniProtKB=G3R5J8 G3R5J8 CTSW PTHR12411:SF101 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN W cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000008526.3|UniProtKB=G3QZM2 G3QZM2 ZNF615 PTHR24381:SF479 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 432 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000038942.1|UniProtKB=G3R398 G3R398 PTHR11524:SF32 60S RIBOSOMAL PROTEIN L7 RPL7L1 nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;RNA binding#GO:0003723;structural molecule activity#GO:0005198 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000872.3|UniProtKB=G3QF05 G3QF05 CAND1 PTHR12696:SF1 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1 metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular component assembly#GO:0022607;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein-containing complex assembly#GO:0065003;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein modification process#GO:0036211 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000024364.2|UniProtKB=G3SJS1 G3SJS1 PTHR11736:SF66 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MAGE-LIKE PROTEIN 2 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022720.2|UniProtKB=A0A2I2Y1Q5 A0A2I2Y1Q5 PTHR11758:SF34 40S RIBOSOMAL PROTEIN S15A SMALL RIBOSOMAL SUBUNIT PROTEIN US8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000043676.1|UniProtKB=A0A2I2YZI5 A0A2I2YZI5 DTD2 PTHR10472:SF1 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;deacylase activity#GO:0160215;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689 nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000012506.3|UniProtKB=G3R9V3 G3R9V3 TMPRSS11A PTHR24253:SF41 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11A serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000014344.3|UniProtKB=G3REL1 G3REL1 LOC101139746 PTHR42884:SF28 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 7 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 GORGO|Ensembl=ENSGGOG00000040976.1|UniProtKB=A0A2I2YG80 A0A2I2YG80 PTHR13044:SF36 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 BZIP DOMAIN-CONTAINING PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010366.3|UniProtKB=G3RTU9 G3RTU9 BAX PTHR11256:SF42 BCL-2 RELATED APOPTOSIS REGULATOR BAX channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;regulation of neuron apoptotic process#GO:0043523;organelle organization#GO:0006996;response to stress#GO:0006950;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;signaling#GO:0023052;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;positive regulation of cellular process#GO:0048522;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;positive regulation of neuron apoptotic process#GO:0043525;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;mitochondrial fusion#GO:0008053;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of cellular process#GO:0050794;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 p53 pathway#P00059>BAX#G01581;CCKR signaling map#P06959>BAX#P07159;Huntington disease#P00029>Bax#G01533;Apoptosis signaling pathway#P00006>Bax#P00271 GORGO|Ensembl=ENSGGOG00000004562.3|UniProtKB=G3S7K1 G3S7K1 CMAH PTHR46522:SF1 CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE INACTIVE CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;hydroxylase#PC00122 GORGO|Ensembl=ENSGGOG00000014855.4|UniProtKB=G3RFW5 G3RFW5 DEPDC1B PTHR16206:SF11 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 1B regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signal transduction#GO:0009967;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;positive regulation of signaling#GO:0023056 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008316.3|UniProtKB=G3QZ26 G3QZ26 RBBP9 PTHR15394:SF3 SERINE HYDROLASE RBBP9 SERINE HYDROLASE RBBP9 GORGO|Ensembl=ENSGGOG00000009673.3|UniProtKB=A0A2I2YTI9 A0A2I2YTI9 LOC101142284 PTHR24291:SF5 CYTOCHROME P450 FAMILY 4 1,25-DIHYDROXYVITAMIN D(3) 24-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 response to oxygen-containing compound#GO:1901700;steroid catabolic process#GO:0006706;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;vitamin D metabolic process#GO:0042359;lipid catabolic process#GO:0016042;cellular process#GO:0009987;response to nutrient levels#GO:0031667;steroid metabolic process#GO:0008202;response to chemical#GO:0042221;response to lipid#GO:0033993 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 Vitamin D metabolism and pathway#P04396>24-Hydroxylase#P04608;Vitamin D metabolism and pathway#P04396>24-Hydroxylase#G04688 GORGO|Ensembl=ENSGGOG00000016392.3|UniProtKB=G3S099 G3S099 SIDT1 PTHR12185:SF15 SID1 TRANSMEMBRANE FAMILY MEMEBER SID1 TRANSMEMBRANE FAMILY MEMBER 1 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;RNA binding#GO:0003723;nucleobase-containing compound transmembrane transporter activity#GO:0015932 transport#GO:0006810;establishment of localization#GO:0051234;nucleic acid transport#GO:0050657;localization#GO:0051179;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;vacuole#GO:0005773;membrane#GO:0016020;cell periphery#GO:0071944;lysosome#GO:0005764 GORGO|Ensembl=ENSGGOG00000042105.1|UniProtKB=A0A2I2Y8A7 A0A2I2Y8A7 PTHR11772:SF39 ASPARAGINE SYNTHETASE GLUTAMINE AMIDOTRANSFERASE TYPE-2 DOMAIN-CONTAINING PROTEIN ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000009494.3|UniProtKB=G3R236 G3R236 SLC35G6 PTHR22911:SF110 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G3-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000036237.1|UniProtKB=G3S4D2 G3S4D2 H2AC12 PTHR23430:SF29 HISTONE H2A HISTONE H2A TYPE 1-H structural molecule activity#GO:0005198 chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000043302.1|UniProtKB=A0A2I2YT73 A0A2I2YT73 LOC101151848 PTHR10579:SF42 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CHLORIDE CHANNEL ACCESSORY 3B ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000039256.1|UniProtKB=A0A2I2ZD25 A0A2I2ZD25 LOC109029066 PTHR11375:SF5 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER E binding#GO:0005488;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;histone binding#GO:0042393;phosphatase regulator activity#GO:0019208;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772 regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008348.3|UniProtKB=G3QZ66 G3QZ66 PTHR24206:SF103 OS06G0237300 PROTEIN LIM DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000014937.3|UniProtKB=G3RG39 G3RG39 MAPKAPK3 PTHR24349:SF64 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 3 kinase activity#GO:0016301;transferase activity#GO:0016740;calmodulin binding#GO:0005516;mitogen-activated protein kinase binding#GO:0051019;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;calcium/calmodulin-dependent protein kinase activity#GO:0004683;kinase binding#GO:0019900;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 toll-like receptor signaling pathway#GO:0002224;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;response to peptide#GO:1901652;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of response to external stimulus#GO:0032101;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Angiogenesis#P00005>MAPKAPK2/3#P00244;p38 MAPK pathway#P05918>MAPKAP-K3#P05919;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415;Ras Pathway#P04393>MAPKAP#P04564 GORGO|Ensembl=ENSGGOG00000041659.1|UniProtKB=A0A2I2Z9R9 A0A2I2Z9R9 PTHR12884:SF23 60S RIBOSOMAL PROTEIN L29 LARGE RIBOSOMAL SUBUNIT PROTEIN EL29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006162.3|UniProtKB=G3QTK3 G3QTK3 ARCN1 PTHR10121:SF0 COATOMER SUBUNIT DELTA COATOMER SUBUNIT DELTA protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;organelle localization#GO:0051640;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000027042.2|UniProtKB=G3SAD8 G3SAD8 PDP1 PTHR13832:SF627 PROTEIN PHOSPHATASE 2C [PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 1, MITOCHONDRIAL phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000011640.3|UniProtKB=G3R7L2 G3R7L2 PAXX PTHR28586:SF1 PROTEIN PAXX PROTEIN PAXX response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 nucleus#GO:0005634;DNA repair complex#GO:1990391;site of double-strand break#GO:0035861;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000006175.3|UniProtKB=G3QTL6 G3QTL6 PTHR46923:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2 cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sexual reproduction#GO:0019953;spermatid development#GO:0007286;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;cilium-dependent cell motility#GO:0060285;anatomical structure development#GO:0048856;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;sperm motility#GO:0097722;developmental process involved in reproduction#GO:0003006;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;fertilization#GO:0009566;cell development#GO:0048468;cell differentiation#GO:0030154;cell motility#GO:0048870;microtubule-based movement#GO:0007018;gamete generation#GO:0007276;spermatogenesis#GO:0007283;developmental process#GO:0032502;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;cell maturation#GO:0048469;cellular developmental process#GO:0048869;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;sperm capacitation#GO:0048240;developmental maturation#GO:0021700;male gamete generation#GO:0048232 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;CatSper complex#GO:0036128;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011611.3|UniProtKB=G3R7I9 G3R7I9 ALG8 PTHR12413:SF2 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000025324.2|UniProtKB=G3RQG7 G3RQG7 TMA16 PTHR13349:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001871.3|UniProtKB=G3QHL2 G3QHL2 ARHGEF37 PTHR22834:SF9 NUCLEAR FUSION PROTEIN FUS2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 37 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000000569.3|UniProtKB=G3QE70 G3QE70 ABHD16B PTHR12277:SF37 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ABHD16B phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 organophosphate catabolic process#GO:0046434;glycerolipid catabolic process#GO:0046503;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;phosphorus metabolic process#GO:0006793;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerophospholipid catabolic process#GO:0046475;neutral lipid catabolic process#GO:0046461;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;glycerophospholipid metabolic process#GO:0006650;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000002847.3|UniProtKB=G3S910 G3S910 UGCG PTHR12726:SF0 CERAMIDE GLUCOSYLTRANSFERASE CERAMIDE GLUCOSYLTRANSFERASE glucosyltransferase activity#GO:0046527;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;glycolipid biosynthetic process#GO:0009247;glycosphingolipid biosynthetic process#GO:0006688;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513 cellular anatomical structure#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000042516.1|UniProtKB=A0A2I2YXX0 A0A2I2YXX0 PTHR22879:SF14 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 2A-RELATED GORGO|Ensembl=ENSGGOG00000000659.3|UniProtKB=G3QEF5 G3QEF5 PTBP2 PTHR15592:SF16 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000041553.1|UniProtKB=A0A2I2ZUT4 A0A2I2ZUT4 PTHR12669:SF16 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E BINDING PROTEIN 2 binding#GO:0005488;translation regulator activity#GO:0045182;protein binding#GO:0005515;translation initiation factor binding#GO:0031369 regulation of biological quality#GO:0065008;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;regulation of signaling#GO:0023051;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of synaptic plasticity#GO:0048167;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of trans-synaptic signaling#GO:0099177;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605 translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000041736.1|UniProtKB=A0A2I2ZGP8 A0A2I2ZGP8 RAG1 PTHR11539:SF0 VDJ RECOMBINATION ACTIVATING PROTEIN 1 RAG1 V(D)J RECOMBINATION-ACTIVATING PROTEIN 1 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000027076.2|UniProtKB=G3S4T0 G3S4T0 NALF2 PTHR15819:SF8 TRANSMEMBRANE PROTEIN FAM155 NALCN CHANNEL AUXILIARY FACTOR 2 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108 cellular process#GO:0009987;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000003692.3|UniProtKB=G3QM93 G3QM93 PTHR20515:SF1 BETA-DEFENSIN BETA-DEFENSIN 130A-RELATED protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664 cellular response to chemical stimulus#GO:0070887;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;chemotaxis#GO:0006935;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000004776.3|UniProtKB=G3RQ62 G3RQ62 SLC35B1 PTHR10778:SF10 SOLUTE CARRIER FAMILY 35 MEMBER B SOLUTE CARRIER FAMILY 35 MEMBER B1 UDP-galactose transmembrane transporter activity#GO:0005459;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleotide-sugar transmembrane transport#GO:0015780;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748 endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000010827.3|UniProtKB=G3R5H6 G3R5H6 C7H8orf74 PTHR28457:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 74 GORGO|Ensembl=ENSGGOG00000000239.3|UniProtKB=G3QDC4 G3QDC4 PAGE4 PTHR14047:SF11 P ANTIGEN FAMILY MEMBER 5-RELATED P ANTIGEN FAMILY MEMBER 4 GORGO|Ensembl=ENSGGOG00000015946.3|UniProtKB=G3RM17 G3RM17 STAB1 PTHR24038:SF8 STABILIN STABILIN-1 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000008813.3|UniProtKB=G3R0C9 G3R0C9 GALR2 PTHR24230:SF13 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 2 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000041562.1|UniProtKB=A0A2I2YGQ0 A0A2I2YGQ0 SPRED1 PTHR11202:SF18 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008722.3|UniProtKB=G3R051 G3R051 MMP8 PTHR10201:SF137 MATRIX METALLOPROTEINASE NEUTROPHIL COLLAGENASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Plasminogen activating cascade#P00050>MMP-13#P01250;Plasminogen activating cascade#P00050>pro-MMP-13#P01254 GORGO|Ensembl=ENSGGOG00000023287.2|UniProtKB=G3SEE3 G3SEE3 ZDHHC17 PTHR24161:SF18 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE ZDHHC17 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016962.3|UniProtKB=G3RLB4 G3RLB4 MLXIPL PTHR15741:SF14 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR CARBOHYDRATE-RESPONSIVE ELEMENT-BINDING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000026120.2|UniProtKB=G3SIU1 G3SIU1 PTHR46514:SF8 AMPHIPHYSIN BAR DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 membrane invagination#GO:0010324;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;phagocytosis#GO:0006909;protein-containing complex organization#GO:0043933;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;localization#GO:0051179;plasma membrane organization#GO:0007009;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cell projection organization#GO:0030030;endocytosis#GO:0006897 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001273.3|UniProtKB=G3QG11 G3QG11 LY6E PTHR16983:SF13 UPAR/LY6 DOMAIN-CONTAINING PROTEIN LYMPHOCYTE ANTIGEN 6E molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor inhibitor activity#GO:0030547;neurotransmitter receptor regulator activity#GO:0099602;molecular function inhibitor activity#GO:0140678;signaling receptor binding#GO:0005102;acetylcholine receptor inhibitor activity#GO:0030550;binding#GO:0005488;acetylcholine receptor regulator activity#GO:0030548 synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000016796.3|UniProtKB=G3RKX1 G3RKX1 KMT2B PTHR45838:SF3 HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE 2B N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000006231.3|UniProtKB=G3QTS7 G3QTS7 PLXNB1 PTHR22625:SF36 PLEXIN PLEXIN-B1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell shape#GO:0008360;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;signaling#GO:0023052;synapse assembly#GO:0007416;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;response to stimulus#GO:0050896;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Axon guidance mediated by semaphorins#P00007>plexinB1#P00328 GORGO|Ensembl=ENSGGOG00000002539.3|UniProtKB=G3QJB1 G3QJB1 PIP5KL1 PTHR23086:SF46 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE-LIKE PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;catalytic activity#GO:0003824;transferase activity#GO:0016740;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transferase#PC00220;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000014453.3|UniProtKB=G3REV1 G3REV1 TOP6BL PTHR14652:SF2 TYPE 2 DNA TOPOISOMERASE 6 SUBUNIT B-LIKE TYPE 2 DNA TOPOISOMERASE 6 SUBUNIT B-LIKE meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;meiotic DNA double-strand break formation#GO:0042138;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;organelle fission#GO:0048285;cell cycle#GO:0007049;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;meiosis I#GO:0007127;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;reproductive process#GO:0022414;homologous recombination#GO:0035825 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000028489.2|UniProtKB=G3SIH9 G3SIH9 NDUFV2 PTHR10371:SF3 NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 dehydrogenase#PC00092;oxidoreductase#PC00176 Parkinson disease#P00049>Complex I#P01237 GORGO|Ensembl=ENSGGOG00000022809.2|UniProtKB=A0A2I2YKU3 A0A2I2YKU3 P2RY14 PTHR24233:SF3 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 14 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010862.3|UniProtKB=G3R5L6 G3R5L6 GPATCH1 PTHR13384:SF19 G PATCH DOMAIN-CONTAINING PROTEIN 1 G PATCH DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000015994.3|UniProtKB=G3RIT8 G3RIT8 FASTKD3 PTHR21228:SF9 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA metabolic process#GO:0000959;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA metabolic process#GO:1903311;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;cellular process#GO:0009987;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;nucleic acid biosynthetic process#GO:0141187;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000034911.2|UniProtKB=G3SKU5 G3SKU5 PARD3B PTHR16484:SF4 PARTITIONING DEFECTIVE 3 RELATED PARTITIONING DEFECTIVE 3 HOMOLOG B anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167 localization#GO:0051179;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;microtubule cytoskeleton organization#GO:0000226;cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036 cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;cell-cell junction#GO:0005911;apical plasma membrane#GO:0016324;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;apical part of cell#GO:0045177;apical junction complex#GO:0043296;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000016083.3|UniProtKB=G3RJ24 G3RJ24 SAP130 PTHR13497:SF3 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000022232.2|UniProtKB=G3SCJ2 G3SCJ2 PTDSS1 PTHR15362:SF15 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 1 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000006061.3|UniProtKB=G3QTB9 G3QTB9 ZNF839 PTHR16116:SF5 ZINC FINGER PROTEIN 839 ZINC FINGER PROTEIN 839 GORGO|Ensembl=ENSGGOG00000024693.2|UniProtKB=G3S9L6 G3S9L6 TIMMDC1 PTHR13002:SF1 C3ORF1 PROTEIN-RELATED COMPLEX I ASSEMBLY FACTOR TIMMDC1, MITOCHONDRIAL mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000023183.2|UniProtKB=G3RMM9 G3RMM9 CFL1 PTHR11913:SF17 COFILIN-RELATED COFILIN-1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 supramolecular fiber organization#GO:0097435;cytoskeleton-dependent cytokinesis#GO:0061640;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;cytokinesis#GO:0000910;protein-containing complex disassembly#GO:0032984;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;cell cycle process#GO:0022402;cell division#GO:0051301;cell cycle#GO:0007049;cellular component organization#GO:0016043;mitotic cell cycle process#GO:1903047;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;organelle organization#GO:0006996 cell leading edge#GO:0031252;actin cytoskeleton#GO:0015629;lamellipodium#GO:0030027;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Cofilin#P00508 GORGO|Ensembl=ENSGGOG00000016627.4|UniProtKB=G3RKF8 G3RKF8 LDLRAD3 PTHR24270:SF24 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 3 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000016702.3|UniProtKB=G3RKM0 G3RKM0 BICDL1 PTHR32123:SF12 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 1 microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;vesicle cytoskeletal trafficking#GO:0099518;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000010922.3|UniProtKB=A0A2I2YL88 A0A2I2YL88 MGRN1 PTHR22996:SF2 MAHOGUNIN E3 UBIQUITIN-PROTEIN LIGASE MGRN1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 establishment of localization#GO:0051234;vacuolar transport#GO:0007034;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;intracellular transport#GO:0046907;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;cellular process#GO:0009987;smoothened signaling pathway#GO:0007224;localization#GO:0051179;cell communication#GO:0007154;cellular localization#GO:0051641;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000010664.3|UniProtKB=G3R530 G3R530 PTHR13809:SF6 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-10 molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Enkephalin release#P05913>G-Protein (s)#P05977;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Wnt signaling pathway#P00057>Ggamma#P01465;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002 GORGO|Ensembl=ENSGGOG00000041167.1|UniProtKB=A0A2I2Y8S1 A0A2I2Y8S1 SWT1 PTHR16161:SF0 TRANSCRIPTIONAL PROTEIN SWT1 TRANSCRIPTIONAL PROTEIN SWT1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nuclear mRNA surveillance#GO:0071028;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000009753.3|UniProtKB=G3R2R3 G3R2R3 ZNF543 PTHR24384:SF195 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 543 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008345.3|UniProtKB=G3QZ64 G3QZ64 EPHB2 PTHR46877:SF11 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor B#P01156;Angiogenesis#P00005>EphR#P00212 GORGO|Ensembl=ENSGGOG00000009157.3|UniProtKB=G3R193 G3R193 RIMOC1 PTHR28494:SF1 UPF0600 PROTEIN C5ORF51 RAB7A-INTERACTING MON1-CCZ1 COMPLEX SUBUNIT 1 GORGO|Ensembl=ENSGGOG00000002113.3|UniProtKB=A0A2I2YSR0 A0A2I2YSR0 MTA1 PTHR10865:SF5 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;histone deacetylase binding#GO:0042826;transcription coactivator activity#GO:0003713;binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;response to radiation#GO:0009314;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;DNA damage response#GO:0006974;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;response to stress#GO:0006950;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000015241.3|UniProtKB=A0A2I2ZTI9 A0A2I2ZTI9 PTHR19302:SF33 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 5 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cytoplasmic microtubule organization#GO:0031122;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000011854.3|UniProtKB=G3R874 G3R874 PTPRN PTHR46106:SF1 IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE-LIKE N intracellular protein localization#GO:0008104;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of protein localization to extracellular region#GO:0035592;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;insulin secretion#GO:0030073;response to glucose#GO:0009749;macromolecule localization#GO:0033036;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;peptide hormone secretion#GO:0030072;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;peptide secretion#GO:0002790;signal release#GO:0023061;homeostatic process#GO:0042592;cellular response to stimulus#GO:0051716;protein localization to extracellular region#GO:0071692;regulation of localization#GO:0032879;regulation of transport#GO:0051049;glucose homeostasis#GO:0042593;hormone transport#GO:0009914;chemical homeostasis#GO:0048878;cellular response to glucose stimulus#GO:0071333;response to chemical#GO:0042221;establishment of localization in cell#GO:0051649;cellular response to oxygen-containing compound#GO:1901701;establishment of protein localization#GO:0045184;cellular process#GO:0009987;response to carbohydrate#GO:0009743;secretion by cell#GO:0032940;intracellular glucose homeostasis#GO:0001678;hormone secretion#GO:0046879;protein transport#GO:0015031;regulation of biological quality#GO:0065008;protein secretion#GO:0009306;cellular localization#GO:0051641;response to oxygen-containing compound#GO:1901700;response to monosaccharide#GO:0034284;cellular response to chemical stimulus#GO:0070887;export from cell#GO:0140352;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;carbohydrate homeostasis#GO:0033500;regulation of hormone levels#GO:0010817;response to hexose#GO:0009746 organelle#GO:0043226;endomembrane system#GO:0012505;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;cell junction#GO:0030054;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000001831.3|UniProtKB=G3QHH6 G3QHH6 NFIX PTHR11492:SF3 NUCLEAR FACTOR I NUCLEAR FACTOR 1 X-TYPE RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000005777.3|UniProtKB=G3SEZ8 G3SEZ8 ASH2L PTHR10598:SF0 SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000041524.1|UniProtKB=A0A2I2Y7R1 A0A2I2Y7R1 PTHR10496:SF7 40S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN ES24 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006287.3|UniProtKB=G3QTX2 G3QTX2 PAPOLA PTHR10682:SF9 POLY A POLYMERASE POLY(A) POLYMERASE ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000022021.2|UniProtKB=A0A2I2Z9Q4 A0A2I2Z9Q4 NSMF PTHR32061:SF4 NMDA RECEPTOR SYNAPTONUCLEAR SIGNALING AND NEURONAL MIGRATION FACTOR NMDA RECEPTOR SYNAPTONUCLEAR SIGNALING AND NEURONAL MIGRATION FACTOR positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell migration#GO:0030335;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;regulation of neuron migration#GO:2001222;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000014697.3|UniProtKB=G3RFH8 G3RFH8 RIPOR2 PTHR15829:SF2 PROTEIN KINASE PKN/PRK1, EFFECTOR RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 2 non-receptor serine/threonine protein kinase#PC00167 GORGO|Gene=MT-CYB|UniProtKB=Q9T9Y3 Q9T9Y3 MT-CYB PTHR19271:SF42 CYTOCHROME B CYTOCHROME B oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646 membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275 GORGO|Ensembl=ENSGGOG00000040836.1|UniProtKB=A0A2I2Y8D4 A0A2I2Y8D4 PTHR21569:SF22 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9 structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010799.3|UniProtKB=A0A2I2ZAD5 A0A2I2ZAD5 DNAJC6 PTHR23172:SF4 AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED AUXILIN protein binding#GO:0005515;binding#GO:0005488;clathrin binding#GO:0030276 protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;cellular component disassembly#GO:0022411;localization#GO:0051179;protein-containing complex disassembly#GO:0032984;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;vesicle#GO:0031982;postsynapse#GO:0098794 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000042935.1|UniProtKB=G3QDG7 G3QDG7 SRA1 PTHR18834:SF2 STEROID RECEPTOR RNA ACTIVATOR 1 STEROID RECEPTOR RNA ACTIVATOR 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000001088.3|UniProtKB=A0A2I2YWR5 A0A2I2YWR5 CHPF2 PTHR12369:SF14 CHONDROITIN SYNTHASE CHONDROITIN POLYMERIZING FACTOR 2, NON-CATALYTIC SUBUNIT structural molecule activity#GO:0005198;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;protein complex scaffold activity#GO:0140378;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000004687.3|UniProtKB=G3RNU1 G3RNU1 FBXO38 PTHR14753:SF3 F-BOX ONLY PROTEIN 38 F-BOX ONLY PROTEIN 38 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune response#GO:0050776;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;regulation of leukocyte mediated immunity#GO:0002703;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of response to biotic stimulus#GO:0002833;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein K48-linked ubiquitination#GO:0070936;positive regulation of leukocyte mediated immunity#GO:0002705;post-translational protein modification#GO:0043687;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;regulation of lymphocyte mediated immunity#GO:0002706;positive regulation of adaptive immune response#GO:0002821;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011156.3|UniProtKB=G3R6D7 G3R6D7 ANO3 PTHR12308:SF16 ANOCTAMIN ANOCTAMIN-3 transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000008856.3|UniProtKB=A0A2I2YTE9 A0A2I2YTE9 OR4C5 PTHR48002:SF13 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012023.3|UniProtKB=G3R8L4 G3R8L4 CBY3 PTHR21533:SF17 LEUCINE-RICH PROTEIN SPERM ANNULUS POSITIONING COMPLEX SUBUNIT CHIBBY3 GORGO|Ensembl=ENSGGOG00000014174.3|UniProtKB=A0A2I2YUW1 A0A2I2YUW1 FBXO25 PTHR13123:SF8 LD30288P F-BOX ONLY PROTEIN 25 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000024454.2|UniProtKB=G3S375 G3S375 CDKN2A PTHR24201:SF4 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE INHIBITOR 2A cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell population proliferation#GO:0042127;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;negative regulation of cell population proliferation#GO:0008285;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 p53 pathway#P00059>ARF#P01482;p53 pathway#P00059>ARF#G01574 GORGO|Gene=OR1E1|UniProtKB=Q9TU94 Q9TU94 OR1E1 PTHR48001:SF187 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1E1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043128.1|UniProtKB=A0A2I2YKD2 A0A2I2YKD2 PTHR12653:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;metabolic process#GO:0008152;electron transport chain#GO:0022900 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000002095.3|UniProtKB=G3RUI5 G3RUI5 FBXO2 PTHR12125:SF11 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 2 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009997.3|UniProtKB=G3R3D5 G3R3D5 XPC PTHR12135:SF3 DNA REPAIR PROTEIN XP-C / RAD4 DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000006333.4|UniProtKB=A0A2I2Y3T7 A0A2I2Y3T7 OXSR1 PTHR48012:SF1 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE OSR1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular response to chemical stress#GO:0062197;positive regulation of response to external stimulus#GO:0032103;cellular response to abiotic stimulus#GO:0071214;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cell migration#GO:0030334;response to osmotic stress#GO:0006970;regulation of response to stimulus#GO:0048583;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;regulation of lymphocyte migration#GO:2000401;cellular response to osmotic stress#GO:0071470;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of chemotaxis#GO:0050921;cellular response to stimulus#GO:0051716;hyperosmotic response#GO:0006972;regulation of leukocyte migration#GO:0002685;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000016176.3|UniProtKB=G3RJ98 G3RJ98 NYNRIN PTHR12876:SF2 N4BP1-RELATED PROTEIN NYNRIN catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000000714.3|UniProtKB=G3QEK7 G3QEK7 LTBP3 PTHR24034:SF46 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 3 cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to transforming growth factor beta#GO:0071559;signaling#GO:0023052;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000010605.3|UniProtKB=G3R4X3 G3R4X3 FIBCD1 PTHR19143:SF45 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C DOMAIN-CONTAINING PROTEIN 1 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000005666.3|UniProtKB=G3QSB5 G3QSB5 FPR2 PTHR24225:SF0 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 2 peptide receptor activity#GO:0001653;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;cell communication#GO:0007154;regulation of biological quality#GO:0065008;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000012035.3|UniProtKB=G3R8M3 G3R8M3 TLCD3B PTHR13439:SF15 CT120 PROTEIN CERAMIDE SYNTHASE acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 homeostatic process#GO:0042592;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;ceramide metabolic process#GO:0006672;ceramide biosynthetic process#GO:0046513;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000027494.2|UniProtKB=G3S373 G3S373 LOC101145832 PTHR28620:SF3 CENTROMERE PROTEIN V CENTROMERE PROTEIN V-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000026685.2|UniProtKB=G3SFY3 G3SFY3 TMEM229A PTHR31746:SF2 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229A GORGO|Ensembl=ENSGGOG00000027161.2|UniProtKB=G3S011 G3S011 LOC101150170 PTHR26454:SF15 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C65 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016184.3|UniProtKB=G3RJA6 G3RJA6 PEX3 PTHR28080:SF1 PEROXISOMAL BIOGENESIS FACTOR 3 PEROXISOMAL BIOGENESIS FACTOR 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;peroxisomal transport#GO:0043574;protein transport#GO:0015031 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000012200.4|UniProtKB=G3R951 G3R951 ADAMTSL3 PTHR13723:SF169 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 3 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000009455.3|UniProtKB=G3R201 G3R201 FAM47E PTHR46449:SF3 ZGC:158260 PROTEIN FAM47E nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;positive regulation of biosynthetic process#GO:0009891;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;transcription by RNA polymerase II#GO:0006366;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;DNA-templated transcription initiation#GO:0006352;chromatin remodeling#GO:0006338;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Gene=NDUFS7|UniProtKB=Q0MQH9 Q0MQH9 NDUFS7 PTHR11995:SF22 NADH DEHYDROGENASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;electron transfer activity#GO:0009055;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;transmembrane transport#GO:0055085;cellular respiration#GO:0045333;establishment of localization#GO:0051234;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;monoatomic ion transport#GO:0006811 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000024977.2|UniProtKB=G3RQR5 G3RQR5 PTHR23266:SF387 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000009193.3|UniProtKB=G3R1C5 G3R1C5 ZNF786 PTHR24406:SF46 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED OOCYTE ZINC FINGER PROTEIN XLCOF7.1-LIKE C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000007805.3|UniProtKB=G3QXT8 G3QXT8 ARAP1 PTHR45899:SF3 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;phosphatidylinositol phosphate binding#GO:1901981;molecular function regulator activity#GO:0098772 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344 cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000043385.1|UniProtKB=A0A2I2YYS7 A0A2I2YYS7 PTHR11227:SF52 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 4 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;polysaccharide catabolic process#GO:0000272 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000841.3|UniProtKB=A0A2I2Z435 A0A2I2Z435 RALYL PTHR13968:SF21 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING RALY-LIKE PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004281.3|UniProtKB=A0A2I2ZRD6 A0A2I2ZRD6 PHB2 PTHR23222:SF1 PROHIBITIN PROHIBITIN-2 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000008261.3|UniProtKB=G3SBQ6 G3SBQ6 QRSL1 PTHR11895:SF153 TRANSAMIDASE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;ligase#PC00142 GORGO|Ensembl=ENSGGOG00000013659.3|UniProtKB=A0A2I2YIZ9 A0A2I2YIZ9 SEPTIN10 PTHR18884:SF50 SEPTIN SEPTIN-10 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;intracellular protein localization#GO:0008104;cytokinesis#GO:0000910;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000016984.3|UniProtKB=G3RLD1 G3RLD1 UBQLN2 PTHR10677:SF5 UBIQUILIN UBIQUILIN-2 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488 macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;biological regulation#GO:0065007;macroautophagy#GO:0016236;regulation of metabolic process#GO:0019222;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;vacuole organization#GO:0007033;organelle assembly#GO:0070925;response to endoplasmic reticulum stress#GO:0034976;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;regulation of macroautophagy#GO:0016241;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;cellular component assembly#GO:0022607;proteasomal protein catabolic process#GO:0010498;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003534.3|UniProtKB=A0A2I2ZCE8 A0A2I2ZCE8 LOC101126464 PTHR48002:SF159 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4A16 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013866.3|UniProtKB=G3RDC8 G3RDC8 TENT4A PTHR23092:SF24 POLY(A) RNA POLYMERASE TERMINAL NUCLEOTIDYLTRANSFERASE 4A nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;modification-dependent macromolecule catabolic process#GO:0043632;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000003046.3|UniProtKB=A0A2I2ZCA0 A0A2I2ZCA0 MEOX1 PTHR24328:SF8 HOMEOBOX PROTEIN MOX HOMEOBOX PROTEIN MOX-1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000006933.3|UniProtKB=G3RNQ2 G3RNQ2 GPNMB PTHR11861:SF11 MELANOCYTE PROTEIN PMEL 17-RELATED TRANSMEMBRANE GLYCOPROTEIN NMB integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000026989.2|UniProtKB=G3S1G1 G3S1G1 METTL15 PTHR11265:SF1 S-ADENOSYL-METHYLTRANSFERASE MRAW 12S RRNA N(4)-CYTIDINE METHYLTRANSFERASE METTL15-RELATED catalytic activity, acting on a rRNA#GO:0140102;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;rRNA base methylation#GO:0070475;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000024277.2|UniProtKB=G3SAR8 G3SAR8 PTHR11334:SF34 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER X3 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000011685.3|UniProtKB=G3S808 G3S808 ZNF805 PTHR24384:SF99 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 264 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007644.3|UniProtKB=G3QXD8 G3QXD8 CCNB2 PTHR10177:SF184 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B2 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000039158.1|UniProtKB=A0A2I2ZRA8 A0A2I2ZRA8 COQ10B PTHR12901:SF9 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG B, MITOCHONDRIAL intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016187.3|UniProtKB=G3S5K7 G3S5K7 CBLN3 PTHR22923:SF2 CEREBELLIN-RELATED CEREBELLIN-3 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004596.3|UniProtKB=G3QPK6 G3QPK6 DUSP12 PTHR45848:SF4 DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000005567.3|UniProtKB=G3QS29 G3QS29 RAB39B PTHR47979:SF69 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39B pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;myosin binding#GO:0017022;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;transport#GO:0006810;cellular process#GO:0009987 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000005198.3|UniProtKB=G3QR55 G3QR55 MT4 PTHR23299:SF12 METALLOTHIONEIN METALLOTHIONEIN-4 metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular response to chemical stimulus#GO:0070887;inorganic ion homeostasis#GO:0098771;intracellular monoatomic ion homeostasis#GO:0006873;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;homeostatic process#GO:0042592;response to cadmium ion#GO:0046686;response to metal ion#GO:0010038;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;response to stress#GO:0006950;detoxification of inorganic compound#GO:0061687;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;response to chemical#GO:0042221;detoxification#GO:0098754 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000044053.1|UniProtKB=A0A2I2YV52 A0A2I2YV52 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000034997.2|UniProtKB=G3SKR4 G3SKR4 MTSS1 PTHR15708:SF10 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED PROTEIN MTSS 1 lipid binding#GO:0008289;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;binding#GO:0005488 membrane organization#GO:0061024;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;cellular component biogenesis#GO:0044085;positive regulation of actin filament bundle assembly#GO:0032233;cellular component organization or biogenesis#GO:0071840;cell-cell junction maintenance#GO:0045217;cell-cell junction organization#GO:0045216;regulation of actin filament-based process#GO:0032970;regulation of cellular component biogenesis#GO:0044087;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of actin filament bundle assembly#GO:0032231;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000016229.3|UniProtKB=G3RJE5 G3RJE5 ANKRD61 PTHR24197:SF52 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000023803.2|UniProtKB=A0A2I2Z1H5 A0A2I2Z1H5 LOC101148749 PTHR26454:SF36 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002031.3|UniProtKB=G3QI07 G3QI07 PRG2 PTHR10068:SF16 BONE MARROW PROTEOGLYCAN BONE MARROW PROTEOGLYCAN extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000003120.3|UniProtKB=G3QKT5 G3QKT5 ADNP PTHR15740:SF1 NEUROPROTECTIVE PEPTIDE-CONTAINING PROTEIN ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000003024.3|UniProtKB=G3QKJ6 G3QKJ6 ZKSCAN7 PTHR23226:SF300 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 852 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000000639.3|UniProtKB=G3QED7 G3QED7 ZNF324 PTHR24393:SF151 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 956 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000007911.3|UniProtKB=G3S5N5 G3S5N5 VAV2 PTHR45818:SF4 PROTEIN VAV GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signaling cassette#GO:0141124;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;small GTPase-mediated signal transduction#GO:0007264;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;positive regulation of cellular process#GO:0048522;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of immune response#GO:0050776 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 B cell activation#P00010>vav#P00368;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169 GORGO|Ensembl=ENSGGOG00000034858.2|UniProtKB=G3SKS4 G3SKS4 LAT2 PTHR15646:SF5 LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 2 LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 2 leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell activation#GO:0001775;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;calcium-mediated signaling#GO:0019722;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;lymphocyte activation#GO:0046649;intracellular signaling cassette#GO:0141124;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;B cell activation#GO:0042113 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000008847.3|UniProtKB=G3R0G3 G3R0G3 STX19 PTHR19957:SF29 SYNTAXIN SYNTAXIN-19 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;exocytosis#GO:0006887;vesicle organization#GO:0016050;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;membrane fusion#GO:0061025;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;secretion by cell#GO:0032940;protein transport#GO:0015031;export from cell#GO:0140352;vesicle fusion#GO:0006906;cellular component organization#GO:0016043 cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 GORGO|Ensembl=ENSGGOG00000026252.2|UniProtKB=G3SEP2 G3SEP2 PTHR22442:SF4 FAMILY NOT NAMED PROTEIN FAM169BP GORGO|Ensembl=ENSGGOG00000014034.4|UniProtKB=A0A2I2YSL1 A0A2I2YSL1 LRBA PTHR13743:SF64 BEIGE/BEACH-RELATED LIPOPOLYSACCHARIDE-RESPONSIVE AND BEIGE-LIKE ANCHOR PROTEIN kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;localization#GO:0051179;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;synapse organization#GO:0050808;catabolic process#GO:0009056;cell junction organization#GO:0034330;cellular component organization#GO:0016043 cytosol#GO:0005829;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012255.3|UniProtKB=G3R978 G3R978 SLC2A5 PTHR23503:SF32 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000004396.3|UniProtKB=G3QP30 G3QP30 CC2D1A PTHR13076:SF8 COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1A transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000015926.3|UniProtKB=G3RIM2 G3RIM2 TNNC1 PTHR23064:SF47 TROPONIN TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092 muscle system process#GO:0003012;heart process#GO:0003015;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;neuromuscular process#GO:0050905;muscle contraction#GO:0006936;cardiac muscle contraction#GO:0060048;nervous system process#GO:0050877;circulatory system process#GO:0003013;heart contraction#GO:0060047;system process#GO:0003008 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000012943.3|UniProtKB=G3RAY9 G3RAY9 SPATC1L PTHR22192:SF1 SPERIOLIN SPERIOLIN-LIKE PROTEIN microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000012753.4|UniProtKB=A0A2I2ZQG0 A0A2I2ZQG0 ARHGAP12 PTHR23176:SF107 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 12 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000007522.3|UniProtKB=G3QX32 G3QX32 ANKMY2 PTHR24150:SF8 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000011909.3|UniProtKB=G3R8B0 G3R8B0 RBM12B PTHR13976:SF28 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA-BINDING PROTEIN 12B binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000013203.3|UniProtKB=A0A2I2YP15 A0A2I2YP15 UTP23 PTHR12416:SF3 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;binding#GO:0005488 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000008293.3|UniProtKB=G3QZ08 G3QZ08 DEFB135 PTHR15001:SF10 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 135 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;cell killing#GO:0001906 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000024380.2|UniProtKB=A0A2I2YJY4 A0A2I2YJY4 PTHR21377:SF15 PROTEIN FAM210B, MITOCHONDRIAL DUF1279 DOMAIN-CONTAINING PROTEIN organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000002244.3|UniProtKB=G3QIJ8 G3QIJ8 TRIML1 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004181.3|UniProtKB=G3QNI7 G3QNI7 PTHR12277:SF202 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17A catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 regulation of synapse structure or activity#GO:0050803;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of postsynapse organization#GO:0099175 cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000013390.3|UniProtKB=G3RC40 G3RC40 DHPS PTHR11703:SF0 DEOXYHYPUSINE SYNTHASE DEOXYHYPUSINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 biogenic amine metabolic process#GO:0006576;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000016183.3|UniProtKB=G3RJA7 G3RJA7 SPATA31D1 PTHR21859:SF12 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31D1 GORGO|Ensembl=ENSGGOG00000022613.2|UniProtKB=G3RRH5 G3RRH5 LOC101139122 PTHR26453:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037089.1|UniProtKB=A0A2I2Z5T2 A0A2I2Z5T2 HOXD3 PTHR45664:SF5 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-D3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 embryo development#GO:0009790;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;anterior/posterior pattern specification#GO:0009952;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;skeletal system development#GO:0001501;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000000387.3|UniProtKB=G3QDQ5 G3QDQ5 CAMSAP1 PTHR21595:SF3 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;cytoplasmic microtubule organization#GO:0031122;regulation of cellular process#GO:0050794;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of microtubule-based process#GO:0032886;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein depolymerization#GO:1901880;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;negative regulation of cellular process#GO:0048523 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000005457.3|UniProtKB=G3RUP7 G3RUP7 UPK3B PTHR15446:SF15 UROPLAKIN III UROPLAKIN-3B cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000002137.3|UniProtKB=G3SAS0 G3SAS0 ATXN2 PTHR12854:SF11 ATAXIN 2-RELATED ATAXIN-2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000037211.1|UniProtKB=A0A2I2YE79 A0A2I2YE79 NAA30 PTHR45896:SF1 N-ALPHA-ACETYLTRANSFERASE 30 N-ALPHA-ACETYLTRANSFERASE 30 protein N-acyltransferase activity#GO:0140186;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248 metabolite interconversion enzyme#PC00262;transferase#PC00220;acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000023311.2|UniProtKB=A0A2I2YIE7 A0A2I2YIE7 FUNDC1 PTHR21346:SF2 FUN14 DOMAIN CONTAINING FUN14 DOMAIN-CONTAINING PROTEIN 1 process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;autophagy#GO:0006914;cellular process#GO:0009987;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966 GORGO|Ensembl=ENSGGOG00000006849.3|UniProtKB=G3QVD8 G3QVD8 C1H1orf53 PTHR21037:SF2 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 53 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000034963.2|UniProtKB=G3SKH6 G3SKH6 DNAH3 PTHR46961:SF13 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN HEAVY CHAIN, CYTOPLASMIC-LIKE PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000008032.3|UniProtKB=G3QYC1 G3QYC1 FAM163A PTHR31914:SF2 PROTEIN FAM163A PROTEIN FAM163A GORGO|Ensembl=ENSGGOG00000012965.3|UniProtKB=A0A2I2ZCZ1 A0A2I2ZCZ1 TTC39A PTHR31859:SF3 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39A GORGO|Ensembl=ENSGGOG00000011404.3|UniProtKB=G3R6Z8 G3R6Z8 BEST1 PTHR10736:SF4 BESTROPHIN BESTROPHIN-1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000016533.3|UniProtKB=G3RK69 G3RK69 NUDCD1 PTHR21664:SF1 CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66 NUDC DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000014741.3|UniProtKB=A0A2I2YGR1 A0A2I2YGR1 LYSMD4 PTHR20932:SF7 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 4-RELATED GORGO|Ensembl=ENSGGOG00000014586.3|UniProtKB=G3RF69 G3RF69 WDR54 PTHR13720:SF40 WD-40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 54 cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000043018.1|UniProtKB=A0A2I2Y4S6 A0A2I2Y4S6 SPRY1 PTHR12365:SF10 SPROUTY PROTEIN SPROUTY HOMOLOG 1 enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of signal transduction#GO:0009968;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;negative regulation of MAPK cascade#GO:0043409;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of Ras protein signal transduction#GO:0046578;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Spry#P00541;FGF signaling pathway#P00021>Spry#P00626;EGF receptor signaling pathway#P00018>SPRY#G01511 GORGO|Ensembl=ENSGGOG00000024786.2|UniProtKB=G3S3W3 G3S3W3 PTHR11129:SF4 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT FARNESYLTRANSFERASE, CAAX BOX, ALPHA prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000008313.3|UniProtKB=G3QZ25 G3QZ25 PDZRN3 PTHR15545:SF5 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 E3 UBIQUITIN-PROTEIN LIGASE PDZRN3 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;neuromuscular junction development#GO:0007528;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular component organization#GO:0016043;protein modification by small protein conjugation#GO:0032446;cell junction organization#GO:0034330;protein modification by small protein conjugation or removal#GO:0070647;synapse organization#GO:0050808;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cell junction#GO:0030054;neuromuscular junction#GO:0031594;cellular anatomical structure#GO:0110165;synapse#GO:0045202 GORGO|Ensembl=ENSGGOG00000016624.3|UniProtKB=G3RKG5 G3RKG5 MYLK PTHR47633:SF1 IMMUNOGLOBULIN MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008;multicellular organismal process#GO:0032501 intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;stress fiber#GO:0001725;membraneless organelle#GO:0043228;cleavage furrow#GO:0032154;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;actomyosin#GO:0042641;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 GORGO|Ensembl=ENSGGOG00000034879.2|UniProtKB=A0A2I2YWG1 A0A2I2YWG1 SLMAP PTHR15715:SF22 CENTROSOMAL PROTEIN OF 170 KDA SARCOLEMMAL MEMBRANE-ASSOCIATED PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of biological quality#GO:0065008;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of membrane potential#GO:0042391;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027578.2|UniProtKB=G3S9X9 G3S9X9 LOC101143271 PTHR11587:SF5 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Arginine biosynthesis#P02728>Argininosuccinate synthase#P02840 GORGO|Ensembl=ENSGGOG00000005110.3|UniProtKB=G3QQY0 G3QQY0 PAK5 PTHR45832:SF4 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED SERINE_THREONINE-PROTEIN KINASE PAK 5 ISOFORM X1 GORGO|Ensembl=ENSGGOG00000003319.3|UniProtKB=G3QLB2 G3QLB2 SRGN PTHR17178:SF0 SECRETORY GRANULE PROTEOGLYCAN CORE PROTEIN SERGLYCIN organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;response to stimulus#GO:0050896;signaling#GO:0023052;cellular localization#GO:0051641;localization#GO:0051179;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 GORGO|Ensembl=ENSGGOG00000038427.1|UniProtKB=A0A2I2ZUT6 A0A2I2ZUT6 PTHR21569:SF41 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000022933.2|UniProtKB=G3S112 G3S112 PDCD2L PTHR46421:SF1 PROGRAMMED CELL DEATH PROTEIN 2-LIKE US5 ASSEMBLY CHAPERONE PDCD2L programmed cell death#GO:0012501;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000023197.2|UniProtKB=G3RTS0 G3RTS0 KIAA0586 PTHR15721:SF2 KIAA0586 PROTEIN PROTEIN TALPID3 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000006664.3|UniProtKB=G3QUW9 G3QUW9 MIS18BP1 PTHR16124:SF3 MIS18-BINDING PROTEIN 1 MIS18-BINDING PROTEIN 1 membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000000962.3|UniProtKB=G3QF82 G3QF82 NUBP1 PTHR23264:SF35 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1 binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000024196.2|UniProtKB=G3SCG3 G3SCG3 FAM43A PTHR11232:SF36 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN FAM43A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 scaffold/adaptor protein#PC00226 GORGO|Gene=LHB|UniProtKB=Q2Q1P1 Q2Q1P1 LHB PTHR11515:SF11 GLYCOPROTEIN HORMONE BETA CHAIN LUTROPIN SUBUNIT BETA molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 anatomical structure development#GO:0048856;cell communication#GO:0007154;reproductive system development#GO:0061458;system development#GO:0048731;female gonad development#GO:0008585;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;reproductive process#GO:0022414;reproductive structure development#GO:0048608;signaling#GO:0023052;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;multicellular organismal process#GO:0032501;gonad development#GO:0008406;biological regulation#GO:0065007;sex differentiation#GO:0007548;cellular process#GO:0009987;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>LHbeta#G06688;Gonadotropin-releasing hormone receptor pathway#P06664>3' LHbeta#G06903;Gonadotropin-releasing hormone receptor pathway#P06664>5' LHbeta#G06889;Gonadotropin-releasing hormone receptor pathway#P06664>LHbeta#P06751 GORGO|Ensembl=ENSGGOG00000003999.3|UniProtKB=A0A2I2YFU5 A0A2I2YFU5 CREM PTHR45879:SF4 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CAMP-RESPONSIVE ELEMENT MODULATOR double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of nucleobase-containing compound metabolic process#GO:0019219;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;CCKR signaling map#P06959>ICER#P07027;Enkephalin release#P05913>CREB#P05971;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 GORGO|Ensembl=ENSGGOG00000016531.3|UniProtKB=G3RK66 G3RK66 LOC101129522 PTHR24299:SF8 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1A1 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 xenobiotic metabolic process#GO:0006805;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;steroid catabolic process#GO:0006706;regulation of biological quality#GO:0065008;estrogen metabolic process#GO:0008210;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;cellular response to xenobiotic stimulus#GO:0071466;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;response to chemical#GO:0042221;hormone metabolic process#GO:0042445;cellular process#GO:0009987;lipid catabolic process#GO:0016042;secondary metabolic process#GO:0019748;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000012547.3|UniProtKB=G3R9Y4 G3R9Y4 C1QL4 PTHR22923:SF67 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 4 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008371.3|UniProtKB=G3SBR4 G3SBR4 TRIM26 PTHR24103:SF369 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 26 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009496.3|UniProtKB=G3R239 G3R239 VAT1L PTHR44054:SF2 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE NADPH-DEPENDENT QUINONE OXIDOREDUCTASE VAT1L-RELATED Huntington disease#P00029>PIG3#G01535 GORGO|Ensembl=ENSGGOG00000016008.3|UniProtKB=G3SDH6 G3SDH6 PIN4 PTHR45995:SF2 FAMILY NOT NAMED PEPTIDYLPROLYL ISOMERASE nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Gene=1A03_GORGO|UniProtKB=P30377 P30377 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823;peptide binding#GO:0042277 regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of immune system process#GO:0002684 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000003067.3|UniProtKB=A0A2I2Z3Y6 A0A2I2Z3Y6 CNGA3 PTHR45638:SF6 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-3 channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;heterocyclic compound binding#GO:1901363;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;purine ribonucleotide binding#GO:0032555;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076 visual system development#GO:0150063;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;localization#GO:0051179;monoatomic cation transport#GO:0006812;anatomical structure development#GO:0048856;transmembrane transport#GO:0055085;system development#GO:0048731;monoatomic ion transport#GO:0006811;eye development#GO:0001654;sensory system development#GO:0048880;cellular process#GO:0009987;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;retina development in camera-type eye#GO:0060041;monoatomic ion transmembrane transport#GO:0034220;sensory organ development#GO:0007423;sensory perception of chemical stimulus#GO:0007606;developmental process#GO:0032502;transport#GO:0006810;multicellular organism development#GO:0007275;animal organ development#GO:0048513;establishment of localization#GO:0051234;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 ion channel#PC00133;ligand-gated ion channel#PC00141 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 GORGO|Ensembl=ENSGGOG00000027393.2|UniProtKB=G3RRM3 G3RRM3 EXOC6 PTHR12702:SF2 SEC15 EXOCYST COMPLEX COMPONENT 6 export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810 vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;exocyst#GO:0000145 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005488.3|UniProtKB=G3QRV8 G3QRV8 CFAP20 PTHR12458:SF11 ORF PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 20 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;motile cilium assembly#GO:0044458;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell projection organization#GO:0030030;sperm motility#GO:0097722;anatomical structure morphogenesis#GO:0009653;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;organelle assembly#GO:0070925 cytoplasmic microtubule#GO:0005881;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 GORGO|Ensembl=ENSGGOG00000025981.2|UniProtKB=G3S367 G3S367 LECT2 PTHR11329:SF0 LEUKOCYTE CELL-DERIVED CHEMOTAXIN 2 LEUKOCYTE CELL-DERIVED CHEMOTAXIN-2 cytokine#PC00083;chemokine#PC00074 GORGO|Ensembl=ENSGGOG00000005008.3|UniProtKB=G3QQN8 G3QQN8 ZFHX2 PTHR45891:SF1 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011564.3|UniProtKB=G3R7E2 G3R7E2 ARHGDIA PTHR10980:SF9 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 1 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000008120.3|UniProtKB=G3S0F0 G3S0F0 RPH3A PTHR45729:SF3 RABPHILIN, ISOFORM A RABPHILIN-3A regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;exocytosis#GO:0006887;positive regulation of vesicle fusion#GO:0031340;regulation of localization#GO:0032879;vesicle-mediated transport in synapse#GO:0099003;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;positive regulation of cellular component organization#GO:0051130;positive regulation of secretion#GO:0051047;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;export from cell#GO:0140352;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of exocytosis#GO:0017157;secretion#GO:0046903;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916 organelle membrane#GO:0031090;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;bounding membrane of organelle#GO:0098588;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;synaptic membrane#GO:0097060;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;postsynaptic membrane#GO:0045211;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular vesicle#GO:0097708;postsynapse#GO:0098794 GORGO|Ensembl=ENSGGOG00000016282.3|UniProtKB=G3S0X3 G3S0X3 C10H12orf56 PTHR35354:SF1 RGD1561648 SIMILAR TO HUMAN CHROMOSOME 12 OPEN READING FRAME 56 GORGO|Ensembl=ENSGGOG00000005895.3|UniProtKB=G3QSX3 G3QSX3 GDF10 PTHR11848:SF145 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 10 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of developmental process#GO:0050793;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000026736.2|UniProtKB=G3SFF2 G3SFF2 TIGD2 PTHR19303:SF22 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000041943.1|UniProtKB=A0A2I2ZYT6 A0A2I2ZYT6 PTHR11071:SF437 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000002272.3|UniProtKB=G3SD64 G3SD64 ADGRA1 PTHR45930:SF3 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A1 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000034999.2|UniProtKB=G3SKK0 G3SKK0 UBAC2 PTHR43066:SF28 RHOMBOID-RELATED PROTEIN UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 2 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000003938.3|UniProtKB=G3QMW6 G3QMW6 PSME3IP1 PTHR13495:SF0 NEFA-INTERACTING NUCLEAR PROTEIN NIP30 PSME3-INTERACTING PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000026977.2|UniProtKB=A0A2I2YTE2 A0A2I2YTE2 PTHR22960:SF25 MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000002741.3|UniProtKB=G3QJU5 G3QJU5 RHOC PTHR24072:SF100 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOC carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787 organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;mitotic cell cycle process#GO:1903047;actin filament organization#GO:0007015;cell cycle#GO:0007049;cell division#GO:0051301;cellular response to stimulus#GO:0051716;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435 cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507;Angiogenesis#P00005>GTPase#P00254;Integrin signalling pathway#P00034>Rho#P00948;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Ras Pathway#P04393>Rho#P04578;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Axon guidance mediated by semaphorins#P00007>Rho#P00341 GORGO|Ensembl=ENSGGOG00000024275.2|UniProtKB=A0A2I2ZYN5 A0A2I2ZYN5 PTHR11994:SF47 60S RIBOSOMAL PROTEIN L11-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL5 nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;RNA binding#GO:0003723;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000015235.3|UniProtKB=G3RGV7 G3RGV7 PADI3 PTHR10837:SF21 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE TYPE-3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008202.3|UniProtKB=G3S8N9 G3S8N9 SMOC1 PTHR12352:SF13 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 1 binding#GO:0005488;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;heparin binding#GO:0008201;extracellular matrix binding#GO:0050840 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000007563.3|UniProtKB=G3QX68 G3QX68 ALG3 PTHR12646:SF0 NOT56 - RELATED DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000042236.1|UniProtKB=G3RWR9 G3RWR9 S100A8 PTHR11639:SF5 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A8 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 cell-cell adhesion#GO:0098609;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;leukocyte cell-cell adhesion#GO:0007159;response to lipid#GO:0033993;granulocyte migration#GO:0097530;response to chemical#GO:0042221;taxis#GO:0042330;neutrophil migration#GO:1990266;neutrophil chemotaxis#GO:0030593;response to lipopolysaccharide#GO:0032496;response to molecule of bacterial origin#GO:0002237;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;cell adhesion#GO:0007155;response to oxygen-containing compound#GO:1901700;endothelial cell migration#GO:0043542;cell migration#GO:0016477;response to other organism#GO:0051707;leukocyte migration#GO:0050900;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;response to bacterium#GO:0009617;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cell chemotaxis#GO:0060326 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000005608.3|UniProtKB=G3QS63 G3QS63 JTB PTHR13041:SF3 JTB PROTEIN-RELATED PROTEIN JTB mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819 GORGO|Ensembl=ENSGGOG00000038897.1|UniProtKB=G3RRD5 G3RRD5 KCTD11 PTHR14499:SF7 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014114.3|UniProtKB=A0A2I2Z7T8 A0A2I2Z7T8 KLK11 PTHR24271:SF68 KALLIKREIN-RELATED KALLIKREIN-11 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000024890.2|UniProtKB=G3SDV5 G3SDV5 SAC3D1 PTHR12436:SF38 80 KDA MCM3-ASSOCIATED PROTEIN SAC3 DOMAIN-CONTAINING PROTEIN 1 macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;macromolecule metabolic process#GO:0043170;spindle organization#GO:0007051;establishment of localization#GO:0051234;cell cycle#GO:0007049;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleocytoplasmic transport#GO:0006913;organelle assembly#GO:0070925;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;microtubule cytoskeleton organization#GO:0000226;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;gene expression#GO:0010467;chromosome segregation#GO:0007059;metabolic process#GO:0008152;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641 organelle#GO:0043226;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;cytoskeleton#GO:0005856;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025236.2|UniProtKB=G3RTM5 G3RTM5 PTHR11937:SF547 ACTIN POTE ANKYRIN DOMAIN FAMILY MEMBER E-RELATED kinase binding#GO:0019900;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;axon development#GO:0061564;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell differentiation#GO:0030154;cell projection organization#GO:0030030 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;supramolecular fiber#GO:0099512;neuron projection#GO:0043005;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin filament#GO:0005884;cell junction#GO:0030054;histone acetyltransferase complex#GO:0000123;chromosome#GO:0005694;plasma membrane bounded cell projection#GO:0120025;catalytic complex#GO:1902494;axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;H4 histone acetyltransferase complex#GO:1902562;cytoskeleton#GO:0005856;transferase complex#GO:1990234;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular protein-containing complex#GO:0140535 actin and actin related protein#PC00039 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Cadherin signaling pathway#P00012>F-actin#P00470;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944 GORGO|Ensembl=ENSGGOG00000004075.3|UniProtKB=G3RA67 G3RA67 ITGAX PTHR23220:SF135 INTEGRIN ALPHA INTEGRIN ALPHA-X molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;membrane#GO:0016020;membrane protein complex#GO:0098796;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000026102.2|UniProtKB=G3SB92 G3SB92 DDX55 PTHR24031:SF2 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX55 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000002919.3|UniProtKB=G3QK99 G3QK99 LOC101148012 PTHR24247:SF14 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 5B ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;cation binding#GO:0043169;serotonin binding#GO:0051378;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;heterocyclic compound binding#GO:1901363;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 GORGO|Ensembl=ENSGGOG00000008131.3|UniProtKB=G3QYK8 G3QYK8 QRFPR PTHR24241:SF119 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PYROGLUTAMYLATED RF-AMIDE PEPTIDE RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002972.3|UniProtKB=A0A2I2ZW76 A0A2I2ZW76 INTU PTHR21082:SF4 PROTEIN INTURNED PROTEIN INTURNED anatomical structure development#GO:0048856;system development#GO:0048731;cilium organization#GO:0044782;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000013760.3|UniProtKB=G3S9V4 G3S9V4 SPATA46 PTHR33517:SF4 PROTEIN FAM170B-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 46 fertilization#GO:0009566;reproductive process#GO:0022414;sexual reproduction#GO:0019953 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane#GO:0016020;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040202.1|UniProtKB=A0A2I2YZE0 A0A2I2YZE0 PTHR18919:SF150 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407 lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000000870.3|UniProtKB=G3QEZ9 G3QEZ9 WNT10A PTHR12027:SF89 WNT RELATED PROTEIN WNT-10A protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109 nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;signaling#GO:0023052;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system development#GO:0048731;cell fate commitment#GO:0045165;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 GORGO|Ensembl=ENSGGOG00000009197.3|UniProtKB=A0A2I2YFJ5 A0A2I2YFJ5 PTHR11426:SF293 HISTONE H3 HISTONE H3.3C mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;organelle fission#GO:0048285;kinetochore organization#GO:0051383;localization#GO:0051179;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 GORGO|Ensembl=ENSGGOG00000028315.2|UniProtKB=G3SD77 G3SD77 TSC22D4 PTHR47610:SF1 TSC22 DOMAIN FAMILY PROTEIN 4 TSC22 DOMAIN FAMILY PROTEIN 4 GORGO|Ensembl=ENSGGOG00000015422.3|UniProtKB=G3RHD0 G3RHD0 RIPK4 PTHR24198:SF65 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 4 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000008194.3|UniProtKB=G3QYR5 G3QYR5 PTHR16181:SF34 PROTEIN FAM83A-RELATED PROTEIN FAM83A kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 regulation of cellular process#GO:0050794;epidermal growth factor receptor signaling pathway#GO:0007173;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 GORGO|Ensembl=ENSGGOG00000006561.3|UniProtKB=G3QUL5 G3QUL5 PSMA5 PTHR11599:SF14 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-5 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;proteasome complex#GO:0000502;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000014437.3|UniProtKB=G3RET4 G3RET4 MED22 PTHR12434:SF6 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000011184.3|UniProtKB=G3R6F4 G3R6F4 IL26 PTHR48482:SF1 INTERLEUKIN-19-RELATED INTERLEUKIN-26 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;immune system process#GO:0002376;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of cellular process#GO:0050794;negative regulation of inflammatory response#GO:0050728;positive regulation of cell communication#GO:0010647;negative regulation of defense response#GO:0031348;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of response to stress#GO:0080134;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;immune response#GO:0006955 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000012608.3|UniProtKB=A0A2I2YN78 A0A2I2YN78 PRR13 PTHR36287:SF1 FAMILY NOT NAMED PROLINE-RICH PROTEIN 13 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000042888.1|UniProtKB=A0A2I2Z0D7 A0A2I2Z0D7 ZDHHC4 PTHR22883:SF466 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC4 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein targeting#GO:0006605 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007224.3|UniProtKB=G3QWB1 G3QWB1 FEM1C PTHR24173:SF14 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015461.3|UniProtKB=A0A2I2Z1E1 A0A2I2Z1E1 RYR1 PTHR46399:SF10 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 1 gated channel activity#GO:0022836;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261 muscle contraction#GO:0006936;transport#GO:0006810;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;system process#GO:0003008;calcium ion transport#GO:0006816;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;muscle system process#GO:0003012;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;calcium channel complex#GO:0034704;myofibril#GO:0030016;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;sarcoplasmic reticulum membrane#GO:0033017;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;sarcoplasmic reticulum#GO:0016529;contractile muscle fiber#GO:0043292;sarcomere#GO:0030017;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;cation channel complex#GO:0034703;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;monoatomic ion channel complex#GO:0034702;endomembrane system#GO:0012505;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;Z disc#GO:0030018;sarcolemma#GO:0042383;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;I band#GO:0031674 Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441;CCKR signaling map#P06959>RYR1/2/3#P07088 GORGO|Ensembl=ENSGGOG00000006826.3|UniProtKB=G3SKB1 G3SKB1 ATCAY PTHR12112:SF9 BNIP - RELATED CAYTAXIN apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987;programmed cell death#GO:0012501 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000028002.2|UniProtKB=G3RYF1 G3RYF1 PHB1 PTHR23222:SF37 PROHIBITIN PROHIBITIN 1 mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000028275.2|UniProtKB=G3R6V5 G3R6V5 PTHR24377:SF918 IP01015P-RELATED ZINC FINGER PROTEIN 528-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009337.3|UniProtKB=G3R1Q1 G3R1Q1 ARPP21 PTHR15672:SF14 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN CAMP-REGULATED PHOSPHOPROTEIN 21 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000010817.3|UniProtKB=A0A2I2ZR37 A0A2I2ZR37 NECTIN3 PTHR23277:SF12 NECTIN-RELATED NECTIN-3 binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000012042.3|UniProtKB=G3R8M9 G3R8M9 KCNA5 PTHR11537:SF250 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 5 gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;metal ion transport#GO:0030001;action potential#GO:0001508 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;transporter complex#GO:1990351;cell junction#GO:0030054;cell-cell contact zone#GO:0044291;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;anchoring junction#GO:0070161;intercalated disc#GO:0014704 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000040425.1|UniProtKB=A0A2I2YML1 A0A2I2YML1 LOC109029139 PTHR19970:SF18 RIBOSOMAL PROTEIN L39E LARGE RIBOSOMAL SUBUNIT PROTEIN EL39 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000036954.1|UniProtKB=A0A2I2ZWS4 A0A2I2ZWS4 FRAT1 PTHR35154:SF1 GBP PROTEIN PROTO-ONCOGENE FRAT1 positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000010113.3|UniProtKB=G3R3N7 G3R3N7 P3H4 PTHR13986:SF4 PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT ENDOPLASMIC RETICULUM PROTEIN SC65 collagen binding#GO:0005518;binding#GO:0005488;protein-containing complex binding#GO:0044877 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001078.3|UniProtKB=A0A2I2ZZ52 A0A2I2ZZ52 IL5RA PTHR23036:SF17 CYTOKINE RECEPTOR INTERLEUKIN-5 RECEPTOR SUBUNIT ALPHA binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000007042.3|UniProtKB=G3QVV2 G3QVV2 WFDC9 PTHR19441:SF16 WAP four-disulfide core domain protein PROTEIN WFDC9 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;defense response#GO:0006952;response to external stimulus#GO:0009605;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000003700.2|UniProtKB=G3QMA2 G3QMA2 KCNJ11 PTHR11767:SF44 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 11 transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000028212.2|UniProtKB=G3S9V5 G3S9V5 BRD10 PTHR31095:SF3 RIKEN CDNA 9930021J03 GENE BROMODOMAIN CONTAINING 10 GORGO|Ensembl=ENSGGOG00000015389.3|UniProtKB=G3RRC9 G3RRC9 DACT1 PTHR15919:SF12 DAPPER-RELATED DAPPER HOMOLOG 1 regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of JNK cascade#GO:0046328 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Wnt signaling pathway#P00057>Frodo#P01470;Wnt signaling pathway#P00057>Dapper#P01469 GORGO|Gene=TAS2R7|UniProtKB=Q646A2 Q646A2 TAS2R7 PTHR11394:SF58 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 7 taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002384.3|UniProtKB=G3QPH1 G3QPH1 ZNF182 PTHR24377:SF218 IP01015P-RELATED ZINC FINGER PROTEIN 182 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015048.3|UniProtKB=G3RYC1 G3RYC1 TMCO2 PTHR38496:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000009890.3|UniProtKB=A0A2I2Z4S0 A0A2I2Z4S0 OPA3 PTHR12499:SF30 OPTIC ATROPHY 3 PROTEIN OPA3 OPTIC ATROPHY 3 PROTEIN nervous system process#GO:0050877;neuromuscular process#GO:0050905;multicellular organismal process#GO:0032501;system process#GO:0003008 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000042250.1|UniProtKB=A0A2I2YH89 A0A2I2YH89 PTHR11913:SF18 COFILIN-RELATED DESTRIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;protein depolymerization#GO:0051261;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;actin filament depolymerization#GO:0030042 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000037610.1|UniProtKB=G3SBR7 G3SBR7 LOC101145374 PTHR48018:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B8 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005614.3|UniProtKB=G3QS74 G3QS74 GALNT18 PTHR11675:SF37 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 18 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000034954.2|UniProtKB=G3SKN1 G3SKN1 WDR70 PTHR16017:SF0 GASTRULATION DEFECTIVE PROTEIN 1-RELATED WD REPEAT-CONTAINING PROTEIN 70 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000043875.1|UniProtKB=A0A2I2YPW4 A0A2I2YPW4 FGFBP3 PTHR15258:SF3 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 3 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;cellular process#GO:0009987;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;cell communication#GO:0007154 GORGO|Ensembl=ENSGGOG00000002733.3|UniProtKB=G3QJU2 G3QJU2 MCM7 PTHR11630:SF26 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM7 isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA replication initiation#GO:0006270;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;MCM complex#GO:0042555;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000022304.2|UniProtKB=G3RYQ7 G3RYQ7 ASMTL PTHR43213:SF5 BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429 GORGO|Ensembl=ENSGGOG00000002124.3|UniProtKB=G3QI88 G3QI88 ANXA4 PTHR10502:SF28 ANNEXIN ANNEXIN A4 small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phospholipid binding#GO:0005543;ion binding#GO:0043167;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000007104.3|UniProtKB=G3QW04 G3QW04 TUSC2 PTHR15453:SF8 TUMOR SUPPRESSOR CANDIDATE 2 TUMOR SUPPRESSOR CANDIDATE 2 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;defense response#GO:0006952;response to stimulus#GO:0050896;regulation of membrane potential#GO:0042391;inflammatory response#GO:0006954;response to stress#GO:0006950 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000008060.3|UniProtKB=G3QYE7 G3QYE7 PTHR14096:SF40 APOLIPOPROTEIN L APOLIPOPROTEIN L3 lipid binding#GO:0008289;binding#GO:0005488 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000026448.2|UniProtKB=G3S6E3 G3S6E3 LOC101124007 PTHR23089:SF41 HISTIDINE TRIAD HIT PROTEIN HIT DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824 purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 nucleotide phosphatase#PC00173 GORGO|Ensembl=ENSGGOG00000011401.2|UniProtKB=A0A2I2YKD4 A0A2I2YKD4 LOC101150976 PTHR11984:SF56 CONNEXIN GAP JUNCTION GAMMA-3 PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007 cell junction#GO:0030054;anchoring junction#GO:0070161;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 gap junction#PC00105;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000000335.3|UniProtKB=G3SBA6 G3SBA6 YJU2 PTHR12111:SF1 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2 ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000007588.3|UniProtKB=G3QX91 G3QX91 TRPM5 PTHR13800:SF5 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 5 monoatomic ion-gated channel activity#GO:0022839;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604 transport#GO:0006810;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000011380.3|UniProtKB=A0A2I2Z5U4 A0A2I2Z5U4 PTHR24072:SF303 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOG protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 regulation of locomotion#GO:0040012;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;actin filament organization#GO:0007015;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;signal transduction#GO:0007165;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;intracellular signal transduction#GO:0035556;system development#GO:0048731;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cortical cytoskeleton organization#GO:0030865;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;Rac protein signal transduction#GO:0016601;generation of neurons#GO:0048699;establishment or maintenance of cell polarity#GO:0007163 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000023451.2|UniProtKB=A0A2I2Y3H5 A0A2I2Y3H5 PTHR10934:SF6 60S RIBOSOMAL PROTEIN L18 LARGE RIBOSOMAL SUBUNIT PROTEIN EL18 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000038673.1|UniProtKB=G3SA26 G3SA26 PTHR23105:SF130 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER 60S RIBOSOMAL PROTEIN L7A RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000769.3|UniProtKB=A0A2I2ZN22 A0A2I2ZN22 TUBA1C PTHR11588:SF298 TUBULIN TUBULIN ALPHA-1C CHAIN carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;multicellular organismal process#GO:0032501 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 tubulin#PC00228;cytoskeletal protein#PC00085 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 GORGO|Ensembl=ENSGGOG00000010440.3|UniProtKB=G3R4I3 G3R4I3 SLC6A15 PTHR11616:SF101 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT2 monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;branched-chain amino acid transport#GO:0015803;establishment of localization#GO:0051234;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;metal ion transport#GO:0030001;L-leucine transport#GO:0015820;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 GORGO|Ensembl=ENSGGOG00000004755.3|UniProtKB=G3QPZ8 G3QPZ8 GPR17 PTHR24232:SF44 G-PROTEIN COUPLED RECEPTOR URACIL NUCLEOTIDE_CYSTEINYL LEUKOTRIENE RECEPTOR transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000022866.2|UniProtKB=G3RNA1 G3RNA1 PTHR23267:SF518 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-29 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000001561.3|UniProtKB=G3QGS7 G3QGS7 SLC7A6OS PTHR31196:SF2 RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED GORGO|Ensembl=ENSGGOG00000028009.2|UniProtKB=G3S333 G3S333 ZNF800 PTHR21020:SF2 ZINC FINGER PROTEIN 800 ZINC FINGER PROTEIN 800 GORGO|Ensembl=ENSGGOG00000008546.3|UniProtKB=G3QZQ3 G3QZQ3 FANCM PTHR14025:SF20 FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER FANCONI ANEMIA GROUP M PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;four-way junction DNA binding#GO:0000400;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;response to stress#GO:0006950;cellular process#GO:0009987 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000006890.3|UniProtKB=G3QVG8 G3QVG8 KCNB1 PTHR11537:SF63 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 1 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;action potential#GO:0001508;metal ion transport#GO:0030001;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220 cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;synaptic membrane#GO:0097060;neuron projection membrane#GO:0032589;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell projection membrane#GO:0031253;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;axon#GO:0030424;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell body#GO:0044297;plasma membrane protein complex#GO:0098797 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000007399.3|UniProtKB=G3SBG2 G3SBG2 YBX2 PTHR11544:SF61 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011108.3|UniProtKB=G3R681 G3R681 SLC32A1 PTHR48017:SF206 OS05G0424000 PROTEIN-RELATED VESICULAR INHIBITORY AMINO ACID TRANSPORTER glycine transmembrane transporter activity#GO:0015187;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171 glycine transport#GO:0015816;cellular localization#GO:0051641;neutral amino acid transport#GO:0015804;localization#GO:0051179;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836 intracellular vesicle#GO:0097708;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;neuron projection terminus#GO:0044306;dendritic tree#GO:0097447;dendrite#GO:0030425;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;somatodendritic compartment#GO:0036477;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000012067.3|UniProtKB=G3R8R7 G3R8R7 SLC37A1 PTHR43184:SF11 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A1 antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;phosphate transmembrane transporter activity#GO:0005315;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505 carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748;transport#GO:0006810;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001511.3|UniProtKB=G3QGN3 G3QGN3 ACHE PTHR43918:SF11 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093 GORGO|Ensembl=ENSGGOG00000004728.3|UniProtKB=G3QPX4 G3QPX4 CLEC4F PTHR22802:SF238 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER F signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013321.3|UniProtKB=G3SG12 G3SG12 PLA2G4C PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169 phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerophospholipid catabolic process#GO:0046475;organophosphate catabolic process#GO:0046434;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 GORGO|Ensembl=ENSGGOG00000041031.1|UniProtKB=A0A2I2ZLU7 A0A2I2ZLU7 PTHR19969:SF23 SH2-SH3 ADAPTOR PROTEIN-RELATED CRK-LIKE PROTEIN protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971 cell migration#GO:0016477;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of cellular process#GO:0050794;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Crk#P00207;Integrin signalling pathway#P00034>Crk#P00933 GORGO|Ensembl=ENSGGOG00000006630.3|UniProtKB=G3QUT3 G3QUT3 DIS3 PTHR23355:SF35 RIBONUCLEASE EXOSOME COMPLEX EXONUCLEASE RRP44 hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nuclear mRNA surveillance#GO:0071028;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000026473.2|UniProtKB=G3RNH4 G3RNH4 EXOC1 PTHR16092:SF33 SEC3/SYNTAXIN-RELATED EXOCYST COMPLEX COMPONENT 1 small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;cellular process#GO:0009987;cellular localization#GO:0051641;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport to the plasma membrane#GO:0098876;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization within membrane#GO:0051668 vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cytoplasm#GO:0005737;exocyst#GO:0000145;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell cortex#GO:0005938;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150;SNARE protein#PC00034 GORGO|Ensembl=ENSGGOG00000038949.1|UniProtKB=A0A2I2YJR1 A0A2I2YJR1 PTHR23232:SF178 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN 5-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014342.4|UniProtKB=A0A2I2ZC49 A0A2I2ZC49 HUWE1 PTHR11254:SF446 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HUWE1 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cellular response to stimulus#GO:0051716;Golgi organization#GO:0007030;modification-dependent protein catabolic process#GO:0019941;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cellular process#GO:0009987;response to stress#GO:0006950;membrane fusion#GO:0061025;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;nucleus#GO:0005634;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000495.3|UniProtKB=G3QE05 G3QE05 SCAF1 PTHR47013:SF1 SPLICING FACTOR, ARGININE/SERINE-RICH 19 SPLICING FACTOR, ARGININE_SERINE-RICH 19 RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000026716.2|UniProtKB=G3S9U6 G3S9U6 REX1BD PTHR28309:SF1 REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000041500.1|UniProtKB=G3QXM1 G3QXM1 TMEM239 PTHR37356:SF1 TRANSMEMBRANE PROTEIN 239 TRANSMEMBRANE PROTEIN 239 GORGO|Ensembl=ENSGGOG00000009835.3|UniProtKB=G3RPT9 G3RPT9 TKT PTHR43195:SF3 TRANSKETOLASE TRANSKETOLASE cation binding#GO:0043169;transketolase activity#GO:0004802;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;transketolase or transaldolase activity#GO:0016744;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;pentose-phosphate shunt#GO:0006098;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;nucleotide metabolic process#GO:0009117;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;transketolase#PC00221 Pentose phosphate pathway#P02762>Transketolase#P03082 GORGO|Ensembl=ENSGGOG00000016489.3|UniProtKB=G3SDN1 G3SDN1 NEB PTHR46218:SF5 LASP NEBULIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003883.3|UniProtKB=A0A2I2ZMJ2 A0A2I2ZMJ2 NAP1L1 PTHR11875:SF145 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 1 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010336.3|UniProtKB=G3R498 G3R498 ACSM5 PTHR43605:SF6 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM5, MITOCHONDRIAL acyltransferase activity#GO:0016746;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity#GO:0016740;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000027982.2|UniProtKB=G3S9W2 G3S9W2 TBX18 PTHR11267:SF20 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX18 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;regionalization#GO:0003002;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anterior/posterior pattern specification#GO:0009952;cell fate specification#GO:0001708;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anatomical structure formation involved in morphogenesis#GO:0048646;morphogenesis of an epithelium#GO:0002009;cellular process#GO:0009987;embryo development#GO:0009790;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 GORGO|Ensembl=ENSGGOG00000037344.1|UniProtKB=A0A2I2YGM8 A0A2I2YGM8 PTHR23341:SF7 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP AT-HOOK 1 transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;DNA binding#GO:0003677 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000006311.3|UniProtKB=G3QTZ0 G3QTZ0 TARS2 PTHR11451:SF27 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000012248.3|UniProtKB=G3R970 G3R970 PRORP PTHR13547:SF23 RIBONUCLEASE P MITOCHONDRIAL RIBONUCLEASE P CATALYTIC SUBUNIT endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;ribonuclease P activity#GO:0004526 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;nucleic acid biosynthetic process#GO:0141187 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000000698.3|UniProtKB=G3RSC9 G3RSC9 TIMM29 PTHR21435:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 mitochondrial transport#GO:0006839;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;mitochondrial protein import pathway#GO:7770058;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular transport#GO:0046907;transport#GO:0006810 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000025380.2|UniProtKB=G3SC00 G3SC00 SERPIND1 PTHR11461:SF30 SERINE PROTEASE INHIBITOR, SERPIN HEPARIN COFACTOR 2 peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>HCII#P00456 GORGO|Ensembl=ENSGGOG00000028491.2|UniProtKB=G3SAS2 G3SAS2 HAPLN1 PTHR22804:SF10 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 1 anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;extracellular region#GO:0005576;cell junction#GO:0030054 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000005136.3|UniProtKB=G3QR02 G3QR02 CYB5R1 PTHR19370:SF74 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 1 catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on NAD(P)H#GO:0016651 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000023207.2|UniProtKB=G3RPP2 G3RPP2 LOC101141566 PTHR24248:SF179 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594 cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;adrenergic receptor signaling pathway#GO:0071875;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016497.3|UniProtKB=A0A2I2ZV82 A0A2I2ZV82 TMEM176A PTHR15756:SF6 LR8/HCA112 TRANSMEMBRANE PROTEIN 176A GORGO|Ensembl=ENSGGOG00000036127.1|UniProtKB=A0A2I2YTX1 A0A2I2YTX1 RND3 PTHR24072:SF24 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOE protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;actin filament-based process#GO:0030029;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;signaling#GO:0023052 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 GORGO|Ensembl=ENSGGOG00000003402.3|UniProtKB=G3QLI8 G3QLI8 DNASE2 PTHR10858:SF9 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE-2-ALPHA endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;programmed cell death#GO:0012501;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 endodeoxyribonuclease#PC00093 GORGO|Ensembl=ENSGGOG00000021967.2|UniProtKB=G3RND5 G3RND5 RAP2C PTHR24070:SF200 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2C hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of locomotion#GO:0040012 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 GORGO|Ensembl=ENSGGOG00000001950.3|UniProtKB=A0A2I2ZYY6 A0A2I2ZYY6 TMEM245 PTHR21716:SF4 TRANSMEMBRANE PROTEIN TRANSMEMBRANE PROTEIN 245 cellular process#GO:0009987;transport#GO:0006810;organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000023843.2|UniProtKB=G3S820 G3S820 CHMP2A PTHR10476:SF4 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2A cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;late endosome to vacuole transport#GO:0045324;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179 vesicle membrane#GO:0012506;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005513.3|UniProtKB=G3QRY1 G3QRY1 RILP PTHR21502:SF7 ZINC FINGER PROTEIN DZIP1 RAB-INTERACTING LYSOSOMAL PROTEIN small GTPase binding#GO:0031267;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 plasma membrane bounded cell projection organization#GO:0120036;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;organelle assembly#GO:0070925 lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;vacuole#GO:0005773;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;lytic vacuole#GO:0000323 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000005027.3|UniProtKB=G3QQR1 G3QQR1 RALGAPB PTHR21344:SF1 RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 GORGO|Ensembl=ENSGGOG00000000164.3|UniProtKB=G3QD55 G3QD55 LOC101144253 PTHR21859:SF55 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31A1-RELATED GORGO|Ensembl=ENSGGOG00000025020.2|UniProtKB=G3RP68 G3RP68 CCR2 PTHR10489:SF913 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 2 signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;calcium-mediated signaling#GO:0019722;defense response#GO:0006952;response to external stimulus#GO:0009605 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000015305.3|UniProtKB=G3RH15 G3RH15 GPATCH3 PTHR14390:SF3 G PATCH DOMAIN CONTAINING PROTEIN 3 G PATCH DOMAIN-CONTAINING PROTEIN 3 regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of immune system process#GO:0002683;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of signal transduction#GO:0009966;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;negative regulation of multicellular organismal process#GO:0051241;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776 GORGO|Ensembl=ENSGGOG00000007625.3|UniProtKB=G3QXB8 G3QXB8 CLVS1 PTHR10174:SF72 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CLAVESIN-1 binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 cellular component organization#GO:0016043;organelle organization#GO:0006996;lytic vacuole organization#GO:0080171;cellular process#GO:0009987;lysosome organization#GO:0007040;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000011461.3|UniProtKB=G3R747 G3R747 IGFL1 PTHR34827:SF2 INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3-RELATED INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000025266.2|UniProtKB=G3RQS7 G3RQS7 B3GNT2 PTHR11214:SF25 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;aminoglycan biosynthetic process#GO:0006023;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009952.3|UniProtKB=G3R396 G3R396 WDR88 PTHR45048:SF1 FAMILY NOT NAMED WD REPEAT-CONTAINING PROTEIN 88 GORGO|Ensembl=ENSGGOG00000009541.3|UniProtKB=G3RU91 G3RU91 ANGPTL8 PTHR21463:SF0 ANGIOPOIETIN-LIKE PROTEIN 8 ANGIOPOIETIN-LIKE PROTEIN 8 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;lipid homeostasis#GO:0055088;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chemical homeostasis#GO:0048878;regulation of lipid metabolic process#GO:0019216;triglyceride homeostasis#GO:0070328 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000013834.3|UniProtKB=A0A2I2ZS34 A0A2I2ZS34 FBLN7 PTHR24034:SF94 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-7 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000001571.3|UniProtKB=G3QGT7 G3QGT7 TXLNA PTHR16127:SF12 TAXILIN ALPHA-TAXILIN membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000014915.3|UniProtKB=G3SBF7 G3SBF7 UNKL PTHR14493:SF37 UNKEMPT FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE UNKL-RELATED GORGO|Ensembl=ENSGGOG00000008665.3|UniProtKB=G3R002 G3R002 SLC38A3 PTHR22950:SF22 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 3 carboxylic acid transmembrane transporter activity#GO:0046943;aromatic amino acid transmembrane transporter activity#GO:0015173;basic amino acid transmembrane transporter activity#GO:0015174;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 GORGO|Ensembl=ENSGGOG00000007721.3|UniProtKB=A0A2I2ZSY9 A0A2I2ZSY9 SAMD11 PTHR12247:SF67 POLYCOMB GROUP PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 11 histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000013656.3|UniProtKB=G3S8P2 G3S8P2 HDAC9 PTHR10625:SF41 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 9 deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000014748.3|UniProtKB=G3RFL8 G3RFL8 GARIN5A PTHR22574:SF5 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 5A GORGO|Ensembl=ENSGGOG00000027352.2|UniProtKB=G3SA04 G3SA04 RAB9A PTHR47981:SF9 RAB FAMILY RAS-RELATED PROTEIN RAB-9A hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;cellular component biogenesis#GO:0044085;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;membrane fusion#GO:0061025;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;endosomal transport#GO:0016197;vesicle organization#GO:0016050;phagolysosome assembly#GO:0001845;phagocytosis#GO:0006909;intracellular transport#GO:0046907;transport#GO:0006810;lytic vacuole organization#GO:0080171;endocytosis#GO:0006897;vesicle fusion#GO:0006906;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;organelle assembly#GO:0070925 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;late endosome#GO:0005770;phagocytic vesicle#GO:0045335;lytic vacuole#GO:0000323 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000015845.3|UniProtKB=G3RIF1 G3RIF1 SNCB PTHR13820:SF4 SYNUCLEIN BETA-SYNUCLEIN binding#GO:0005488;small molecule binding#GO:0036094;copper ion binding#GO:0005507;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;cellular localization#GO:0051641;cell communication#GO:0007154;localization#GO:0051179;chemical synaptic transmission#GO:0007268;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;regulation of biological process#GO:0050789;endocytosis#GO:0006897;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052 axon#GO:0030424;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;neuronal cell body#GO:0043025;cell projection#GO:0042995;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;axon terminus#GO:0043679;cell junction#GO:0030054;neuron projection#GO:0043005;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Parkinson disease#P00049>beta-Synuclein#P01217 GORGO|Ensembl=ENSGGOG00000043525.1|UniProtKB=G3RD70 G3RD70 PNMA6A PTHR23095:SF40 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 6A transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000024753.2|UniProtKB=G3SBZ3 G3SBZ3 SIRT4 PTHR11085:SF20 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN LIPOAMIDASE SIRTUIN-4, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;pentosyltransferase activity#GO:0016763;acyltransferase activity#GO:0016746;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005452.3|UniProtKB=G3QRS5 G3QRS5 ST6GALNAC5 PTHR23136:SF11 TAX1-BINDING PROTEIN 3-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 5 GORGO|Ensembl=ENSGGOG00000014856.3|UniProtKB=A0A2I2YZK5 A0A2I2YZK5 PLPP2 PTHR10165:SF25 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 2 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 dephosphorylation#GO:0016311;cell communication#GO:0007154;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000026544.2|UniProtKB=A1YEP8 A1YEP8 ZSCAN12 PTHR23226:SF68 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 12 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000017191.3|UniProtKB=A0A2I2Y5I4 A0A2I2Y5I4 MEAF6 PTHR13476:SF0 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000007745.3|UniProtKB=G3QXM8 G3QXM8 KLHL17 PTHR24412:SF475 KELCH PROTEIN KELCH-LIKE PROTEIN 17 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006216.3|UniProtKB=G3SK49 G3SK49 PTHR11834:SF2 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;embryo development#GO:0009790;hippo signaling#GO:0035329;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000002162.2|UniProtKB=G3QIC4 G3QIC4 RPRM PTHR28649:SF6 PROTEIN REPRIMO-RELATED PROTEIN REPRIMO regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005536.4|UniProtKB=A0A2I2Y3Q1 A0A2I2Y3Q1 JARID2 PTHR10694:SF149 LYSINE-SPECIFIC DEMETHYLASE PROTEIN JUMONJI dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;protein demethylase activity#GO:0140457 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000004481.3|UniProtKB=G3QPB2 G3QPB2 PPP1R12B PTHR24179:SF18 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12B enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron differentiation#GO:0030182;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008 I band#GO:0031674;sarcomere#GO:0030017;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;A band#GO:0031672;organelle#GO:0043226;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000008495.3|UniProtKB=G3QZJ1 G3QZJ1 RABEP2 PTHR31179:SF6 RAB GTPASE-BINDING EFFECTOR PROTEIN RAB GTPASE-BINDING EFFECTOR PROTEIN 2 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000015631.3|UniProtKB=G3S071 G3S071 SLC6A3 PTHR11616:SF38 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT DOPAMINE TRANSPORTER establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>DAT#P00065;Parkinson disease#P00049>DAT#P01228;Dopamine receptor mediated signaling pathway#P05912>DAT#P05962;Parkinson disease#P00049>DAT#G01547 GORGO|Ensembl=ENSGGOG00000003314.3|UniProtKB=G3QLA8 G3QLA8 MMP20 PTHR10201:SF125 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-20 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;odontogenesis#GO:0042476;animal organ morphogenesis#GO:0009887;catabolic process#GO:0009056;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;cellular process#GO:0009987;amelogenesis#GO:0097186;odontogenesis of dentin-containing tooth#GO:0042475;developmental process#GO:0032502;metabolic process#GO:0008152;anatomical structure formation involved in morphogenesis#GO:0048646;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000013950.3|UniProtKB=A0A2I2Z6U0 A0A2I2Z6U0 PTHR45973:SF8 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 49 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000012642.3|UniProtKB=G3RA83 G3RA83 EFHC2 PTHR12086:SF11 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2 regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;regulation of dendrite morphogenesis#GO:0048814;cellular component organization#GO:0016043;regulation of developmental process#GO:0050793;regulation of cellular component organization#GO:0051128;regulation of dendrite development#GO:0050773;cell junction organization#GO:0034330;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biological regulation#GO:0065007;nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;developmental process#GO:0032502;growth#GO:0040007;regulation of cell projection organization#GO:0031344;neuromuscular junction development#GO:0007528;regulation of plasma membrane bounded cell projection organization#GO:0120035;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;developmental growth#GO:0048589 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000006335.3|UniProtKB=G3QU15 G3QU15 MYT1 PTHR10816:SF10 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000004372.3|UniProtKB=G3QP07 G3QP07 TERF2 PTHR46833:SF1 TELOMERIC REPEAT-BINDING FACTOR 2 TERF2 TELOMERIC REPEAT-BINDING FACTOR 2 nucleic acid binding#GO:0003676;RNA-directed DNA polymerase activity#GO:0003964;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;binding#GO:0005488;single-stranded DNA binding#GO:0003697;transferase activity#GO:0016740;catalytic activity, acting on DNA#GO:0140097;telomerase activity#GO:0003720;DNA polymerase activity#GO:0034061;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162 cellular process#GO:0009987;telomere capping#GO:0016233;organelle organization#GO:0006996;response to stress#GO:0006950;regulation of telomere maintenance via telomere lengthening#GO:1904356;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cellular response to stress#GO:0033554;regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;intracellular protein localization#GO:0008104;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;regulation of telomere maintenance#GO:0032204;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;negative regulation of organelle organization#GO:0010639;negative regulation of DNA recombination#GO:0045910;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of cellular component organization#GO:0051129;regulation of macromolecule metabolic process#GO:0060255;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;negative regulation of chromosome organization#GO:2001251;telomere organization#GO:0032200;localization#GO:0051179 chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;nuclear telomere cap complex#GO:0000783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;protein-containing complex#GO:0032991;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000002406.3|UniProtKB=G3S787 G3S787 DMRTB1 PTHR12322:SF66 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR B1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;sex differentiation#GO:0007548;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;reproductive process#GO:0022414;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008971.3|UniProtKB=G3R0S7 G3R0S7 PTHR42884:SF8 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 6 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 proteolysis#GO:0006508;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;peptide hormone processing#GO:0016486;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;protein maturation#GO:0051604;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell surface#GO:0009986;Golgi apparatus subcompartment#GO:0098791;extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 GORGO|Ensembl=ENSGGOG00000027742.2|UniProtKB=G3RZH3 G3RZH3 TMEM126A PTHR16296:SF4 UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007 TRANSMEMBRANE PROTEIN 126A mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000015199.3|UniProtKB=G3RGS9 G3RGS9 PTHR13199:SF13 GH03947P ATOS HOMOLOG PROTEIN A GORGO|Ensembl=ENSGGOG00000014256.3|UniProtKB=G3REC4 G3REC4 TMEM120A PTHR46659:SF1 SERINE/THREONINE/TYROSINE-INTERACTING-LIKE PROTEIN 1 SERINE_THREONINE_TYROSINE-INTERACTING-LIKE PROTEIN 1 binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;protein phosphatase binding#GO:0019903;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;positive regulation of apoptotic process#GO:0043065;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of organelle organization#GO:0033043;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cellular component organization#GO:0051128;positive regulation of cell communication#GO:0010647;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000024074.2|UniProtKB=G3SJM7 G3SJM7 IGFL2 PTHR34827:SF7 INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3-RELATED INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 GORGO|Ensembl=ENSGGOG00000036456.1|UniProtKB=A0A2I2YHR4 A0A2I2YHR4 LOC101135486 PTHR10497:SF6 60S RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN EL27 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001461.3|UniProtKB=G3S3A0 G3S3A0 RIT1 PTHR24070:SF208 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RIT1 protein binding#GO:0005515;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ribonucleoside triphosphate phosphatase activity#GO:0017111;calmodulin binding#GO:0005516;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000005869.3|UniProtKB=G3QSU5 G3QSU5 CIMIP1 PTHR31909:SF3 CHROMOSOME 20 ORF85 FAMILY MEMBER CILIARY MICROTUBULE INNER PROTEIN 1 GORGO|Ensembl=ENSGGOG00000025382.2|UniProtKB=G3S074 G3S074 PTHR12138:SF148 PRIMATE-EXPANDED PROTEIN FAMILY SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000026815.2|UniProtKB=G3SAQ1 G3SAQ1 C16H15orf48 PTHR14256:SF3 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE ASSOCIATED SUBUNIT FA4L3 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000013371.3|UniProtKB=G3SB64 G3SB64 CCDC28A PTHR13400:SF3 CHEMOKINE C-C MOTIF RECEPTOR 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 28A developmental process involved in reproduction#GO:0003006;gamete generation#GO:0007276;male gamete generation#GO:0048232;reproductive process#GO:0022414;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;developmental process#GO:0032502;multicellular organismal reproductive process#GO:0048609 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025530.2|UniProtKB=G3SDY7 G3SDY7 PTHR24147:SF52 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 30B GORGO|Ensembl=ENSGGOG00000037834.1|UniProtKB=A0A2I2YK04 A0A2I2YK04 LOC101152728 PTHR22881:SF12 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN-CONTAINING PROTEIN 7 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010191.3|UniProtKB=G3R3V7 G3R3V7 JAGN1 PTHR20955:SF4 PROTEIN JAGUNAL HOMOLOG 1 PROTEIN JAGUNAL HOMOLOG 1 cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;localization#GO:0051179;response to peptide#GO:1901652;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;endoplasmic reticulum organization#GO:0007029;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000025910.2|UniProtKB=G3RVW3 G3RVW3 RPS27L PTHR11594:SF2 40S RIBOSOMAL PROTEIN S27 RIBOSOMAL PROTEIN ES27-LIKE structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;rRNA processing#GO:0006364 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000027841.2|UniProtKB=G3S5C9 G3S5C9 FABP2 PTHR11955:SF89 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, INTESTINAL ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289 lipid transport#GO:0006869;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000001307.3|UniProtKB=G3QG39 G3QG39 LOC101146638 PTHR24300:SF180 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2A6 binding#GO:0005488;tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 secondary metabolic process#GO:0019748;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;olefinic compound metabolic process#GO:0120254;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 Nicotine degradation#P05914>CYP2A6#P05984 GORGO|Ensembl=ENSGGOG00000001230.3|UniProtKB=G3QFX8 G3QFX8 CYRIA PTHR12422:SF4 GH09096P CYFIP-RELATED RAC1 INTERACTOR A GORGO|Ensembl=ENSGGOG00000000740.3|UniProtKB=G3QEN3 G3QEN3 GAK PTHR23172:SF34 AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED CYCLIN-G-ASSOCIATED KINASE protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 transport#GO:0006810;establishment of localization#GO:0051234;cellular component disassembly#GO:0022411;import into cell#GO:0098657;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;cellular component organization#GO:0016043;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;protein-containing complex disassembly#GO:0032984 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006002.3|UniProtKB=G3QT61 G3QT61 ZGLP1 PTHR47341:SF1 GATA-TYPE ZINC FINGER PROTEIN 1 GATA-TYPE ZINC FINGER PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000009764.4|UniProtKB=G3R2S8 G3R2S8 NUBPL PTHR42961:SF4 IRON-SULFUR PROTEIN NUBPL IRON-SULFUR CLUSTER TRANSFER PROTEIN NUBPL iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488 mitochondrion organization#GO:0007005;iron-sulfur cluster assembly#GO:0016226;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000005963.3|UniProtKB=G3QT34 G3QT34 ATP1A3 PTHR43294:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-3 potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;inorganic ion import across plasma membrane#GO:0099587;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000015102.3|UniProtKB=G3RGI4 G3RGI4 KIAA0232 PTHR17611:SF3 DNA SEGMENT, CHR 5, ERATO DOI 579, EXPRESSED KIAA0232 HOMOLOG GORGO|Ensembl=ENSGGOG00000013553.3|UniProtKB=G3RCJ6 G3RCJ6 ATP8B1 PTHR24092:SF48 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IC intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023877.2|UniProtKB=G3S7R5 G3S7R5 BLCAP PTHR13259:SF1 BLADDER CANCER 10 KD PROTEIN HOMOLOG APOPTOSIS INDUCING FACTOR BLCAP GORGO|Ensembl=ENSGGOG00000001631.3|UniProtKB=A0A2I2ZTA5 A0A2I2ZTA5 MCC PTHR23347:SF4 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED COLORECTAL MUTANT CANCER PROTEIN regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007920.3|UniProtKB=A0A2I2YNU6 A0A2I2YNU6 NMU PTHR15390:SF0 NEUROMEDIN-U NEUROMEDIN-U protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;neuropeptide receptor binding#GO:0071855 neuropeptide signaling pathway#GO:0007218;regulation of muscle system process#GO:0090257;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;positive regulation of synaptic transmission#GO:0050806;regulation of muscle contraction#GO:0006937;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of trans-synaptic signaling#GO:0099177;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of system process#GO:0044057;regulation of smooth muscle contraction#GO:0006940 axon terminus#GO:0043679;cell junction#GO:0030054;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;terminal bouton#GO:0043195;cell projection#GO:0042995;neuron projection terminus#GO:0044306;synapse#GO:0045202;cellular anatomical structure#GO:0110165;presynapse#GO:0098793;neuron projection#GO:0043005 GORGO|Ensembl=ENSGGOG00000005304.3|UniProtKB=G3QRE4 G3QRE4 TRIB1 PTHR22961:SF17 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 1 protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000027889.2|UniProtKB=A0A2I2ZN76 A0A2I2ZN76 SLC5A3 PTHR11819:SF150 SOLUTE CARRIER FAMILY 5 SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M-RELATED secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000005345.3|UniProtKB=A0A2I2ZQ76 A0A2I2ZQ76 ENTPD1 PTHR11782:SF32 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 metabolic process#GO:0008152;nucleoside diphosphate metabolic process#GO:0009132;organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000037008.1|UniProtKB=G3R7N0 G3R7N0 PTHR24379:SF66 KRAB AND ZINC FINGER DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000012690.3|UniProtKB=G3RAB2 G3RAB2 CHLSN PTHR22306:SF2 CHROMOSOME 7 OPEN READING FRAME 50 PROTEIN CHOLESIN GORGO|Ensembl=ENSGGOG00000043257.1|UniProtKB=A0A2I2YXJ1 A0A2I2YXJ1 PTHR23073:SF77 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 4 macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 protease#PC00190 GORGO|Ensembl=ENSGGOG00000014687.3|UniProtKB=G3RFG5 G3RFG5 POT1 PTHR14513:SF0 PROTECTION OF TELOMERES 1 PROTECTION OF TELOMERES PROTEIN 1 enzyme inhibitor activity#GO:0004857;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;molecular function regulator activity#GO:0098772;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;molecular function inhibitor activity#GO:0140678;DNA binding#GO:0003677;enzyme regulator activity#GO:0030234 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;telomere organization#GO:0032200;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of telomere maintenance via telomere lengthening#GO:1904356;organelle organization#GO:0006996;telomere capping#GO:0016233;regulation of primary metabolic process#GO:0080090;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;regulation of telomere maintenance#GO:0032204;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;regulation of chromosome organization#GO:0033044;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 nuclear telomere cap complex#GO:0000783;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000041310.1|UniProtKB=A0A2I2YXR1 A0A2I2YXR1 TNFSF12 PTHR15151:SF20 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 12 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 cell communication#GO:0007154;immune system process#GO:0002376;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000024195.2|UniProtKB=G3RC32 G3RC32 RRAGD PTHR11259:SF5 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN D hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553 positive regulation of signaling#GO:0023056;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to stress#GO:0006950;positive regulation of TOR signaling#GO:0032008;negative regulation of catabolic process#GO:0009895;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;regulation of TORC1 signaling#GO:1903432;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;nucleus#GO:0005634;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000009177.3|UniProtKB=G3R1C4 G3R1C4 SCN8A PTHR10037:SF23 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 8 SUBUNIT ALPHA transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;system process#GO:0003008;transport#GO:0006810;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;sensory perception#GO:0007600;nervous system process#GO:0050877;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;sensory perception of pain#GO:0019233;action potential#GO:0001508;sodium ion transport#GO:0006814 protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;transporter complex#GO:1990351;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;axon#GO:0030424 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000003731.3|UniProtKB=G3QMD2 G3QMD2 PTHR12358:SF25 SPHINGOSINE KINASE CERAMIDE KINASE lipid kinase activity#GO:0001727;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006343.3|UniProtKB=G3QU18 G3QU18 ERICH6B PTHR23093:SF17 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 GLUTAMATE-RICH PROTEIN 6B GORGO|Ensembl=ENSGGOG00000015935.3|UniProtKB=G3RIN6 G3RIN6 TACR2 PTHR46925:SF3 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED SUBSTANCE-K RECEPTOR molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of reproductive process#GO:2000241;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000001188.3|UniProtKB=G3QFU3 G3QFU3 DCBLD1 PTHR46806:SF1 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000002197.3|UniProtKB=G3QIF7 G3QIF7 C7 PTHR45742:SF2 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C7 regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778;humoral immune response#GO:0006959;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;complement activation#GO:0006956;immune response#GO:0006955;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of biological process#GO:0050789 extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 complement component#PC00078 GORGO|Ensembl=ENSGGOG00000026202.2|UniProtKB=G3RXD7 G3RXD7 PTHR14614:SF1 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN METHYLTRANSFERASE-LIKE PROTEIN 21E catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000013994.3|UniProtKB=G3RDN9 G3RDN9 SLC25A31 PTHR45635:SF40 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 4 active transmembrane transporter activity#GO:0022804;purine nucleotide transmembrane transporter activity#GO:0015216;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;regulation of membrane permeability#GO:0090559;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000015115.3|UniProtKB=G3RGK5 G3RGK5 SEPTIN11 PTHR18884:SF48 SEPTIN SEPTIN-11 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000014051.3|UniProtKB=G3RDU7 G3RDU7 ACAT2 PTHR18919:SF107 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000009287.3|UniProtKB=A0A2I2Z1V9 A0A2I2Z1V9 MMUT PTHR48101:SF4 METHYLMALONYL-COA MUTASE, MITOCHONDRIAL-RELATED METHYLMALONYL-COA MUTASE, MITOCHONDRIAL intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;isomerase activity#GO:0016853 organophosphate catabolic process#GO:0046434;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;sulfur compound catabolic process#GO:0044273;lipid catabolic process#GO:0016042;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 mutase#PC00160;metabolite interconversion enzyme#PC00262;isomerase#PC00135 Methylmalonyl pathway#P02755>Methylmalonyl-CoA mutase#P03034;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA mutase#P03161 GORGO|Ensembl=ENSGGOG00000026831.2|UniProtKB=G3RTH2 G3RTH2 LOC101146844 PTHR11558:SF11 SPERMIDINE/SPERMINE SYNTHASE SPERMIDINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000038809.1|UniProtKB=A0A2I2ZDX6 A0A2I2ZDX6 LOC109025190 PTHR10552:SF11 U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A' snRNA binding#GO:0017069;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;U2 snRNP#GO:0005686;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;spliceosomal complex#GO:0005681;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000022756.2|UniProtKB=A0A2I2ZY88 A0A2I2ZY88 PTHR11726:SF36 60S RIBOSOMAL PROTEIN L10 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012800.3|UniProtKB=G3RAL2 G3RAL2 GUCA1B PTHR23055:SF11 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 2 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;cation binding#GO:0043169;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851;molecular function regulator activity#GO:0098772 sensory perception of light stimulus#GO:0050953;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;visual perception#GO:0007601;system process#GO:0003008 neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;photoreceptor inner segment#GO:0001917;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000011700.3|UniProtKB=G3R7R2 G3R7R2 TPRN PTHR21685:SF1 TON-B BOX DOMAIN TAPERIN ear development#GO:0043583;neuron development#GO:0048666;nervous system process#GO:0050877;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;sensory organ morphogenesis#GO:0090596;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;sensory perception of sound#GO:0007605;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;inner ear receptor cell stereocilium organization#GO:0060122;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;embryo development#GO:0009790;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;hair cell differentiation#GO:0035315;inner ear morphogenesis#GO:0042472;neuron projection development#GO:0031175;system development#GO:0048731;anatomical structure development#GO:0048856;embryonic organ development#GO:0048568;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;animal organ morphogenesis#GO:0009887;neurogenesis#GO:0022008;system process#GO:0003008;cellular developmental process#GO:0048869;developmental process#GO:0032502;epidermis development#GO:0008544;sensory organ development#GO:0007423;plasma membrane bounded cell projection organization#GO:0120036;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;inner ear development#GO:0048839 stereocilium#GO:0032420;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000038429.1|UniProtKB=A0A2I2ZA39 A0A2I2ZA39 CTXND2 PTHR16736:SF6 CORTEXIN-1-RELATED CORTEXIN DOMAIN CONTAINING 2 GORGO|Ensembl=ENSGGOG00000038568.1|UniProtKB=A0A2I2YKA3 A0A2I2YKA3 HTR2A PTHR24247:SF30 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594 cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;response to oxygen-containing compound#GO:1901700;trans-synaptic signaling#GO:0099537;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to xenobiotic stimulus#GO:0009410;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414 GORGO|Ensembl=ENSGGOG00000011954.3|UniProtKB=G3SCT0 G3SCT0 MRPL27 PTHR15893:SF17 RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000026830.2|UniProtKB=G3RNA2 G3RNA2 PPP1R11 PTHR20835:SF4 E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED E3 UBIQUITIN-PROTEIN LIGASE PPP1R11 binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase binding#GO:0019903 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007824.3|UniProtKB=G3QXT9 G3QXT9 CFAP418 PTHR33958:SF1 PROTEIN C8ORF37 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 418 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell development#GO:0048468;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399 cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ciliary base#GO:0097546;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000008806.3|UniProtKB=G3R0C6 G3R0C6 CKM PTHR11547:SF63 ARGININE OR CREATINE KINASE CREATINE KINASE M-TYPE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775 organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000037763.1|UniProtKB=A0A2I2ZHG9 A0A2I2ZHG9 HIC2 PTHR24399:SF27 ZINC FINGER AND BTB DOMAIN-CONTAINING HYPERMETHYLATED IN CANCER 2 PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015745.3|UniProtKB=G3RI70 G3RI70 ZNF608 PTHR21564:SF4 BRAKELESS PROTEIN ZINC FINGER PROTEIN 608 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000039595.1|UniProtKB=A0A2I2YX69 A0A2I2YX69 PTHR45883:SF6 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN-RELATED heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000022921.2|UniProtKB=G3S9T6 G3S9T6 BPNT1 PTHR43028:SF5 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000026204.2|UniProtKB=G3SJ98 G3SJ98 LHX8 PTHR24208:SF117 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 cellular process#GO:0009987;nervous system development#GO:0007399;head development#GO:0060322;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;forebrain development#GO:0030900;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000022046.2|UniProtKB=G3RNP9 G3RNP9 WRNIP1 PTHR13779:SF7 WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER ATPASE WRNIP1 ATP-dependent activity#GO:0140657;enzyme regulator activity#GO:0030234;ATP-dependent activity, acting on DNA#GO:0008094;molecular function activator activity#GO:0140677;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;enzyme activator activity#GO:0008047;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;molecular function regulator activity#GO:0098772;DNA helicase activity#GO:0003678 cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA helicase#PC00011;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000016625.3|UniProtKB=G3RKF2 G3RKF2 ATP5F1E PTHR12448:SF0 ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT EPSILON, MITOCHONDRIAL channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252 metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000009828.3|UniProtKB=G3R2Z4 G3R2Z4 CFAP91 PTHR22455:SF10 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 GORGO|Ensembl=ENSGGOG00000004959.3|UniProtKB=G3SAM0 G3SAM0 LOC101125455 PTHR12035:SF127 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 11 organic acid binding#GO:0043177;carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000028171.2|UniProtKB=G3RUE9 G3RUE9 E2F6 PTHR12081:SF19 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000005029.3|UniProtKB=G3QQQ5 G3QQQ5 POLL PTHR11276:SF28 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE LAMBDA DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA-directed DNA polymerase activity#GO:0003887 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 GORGO|Ensembl=ENSGGOG00000014392.3|UniProtKB=G3REP7 G3REP7 GC PTHR11385:SF11 SERUM ALBUMIN-RELATED VITAMIN D-BINDING PROTEIN lipid binding#GO:0008289;steroid binding#GO:0005496;binding#GO:0005488;small molecule binding#GO:0036094 response to nutrient levels#GO:0031667;primary metabolic process#GO:0044238;cellular process#GO:0009987;response to stimulus#GO:0050896;steroid metabolic process#GO:0008202;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;vitamin D metabolic process#GO:0042359 transfer/carrier protein#PC00219 Vitamin D metabolism and pathway#P04396>DBP#P04600 GORGO|Ensembl=ENSGGOG00000001897.3|UniProtKB=G3QHN2 G3QHN2 NELFB PTHR13503:SF3 NEGATIVE ELONGATION FACTOR COMPLEX MEMBER B NEGATIVE ELONGATION FACTOR B regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;stem cell differentiation#GO:0048863;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605 intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000005477.3|UniProtKB=A0A2I2YGE1 A0A2I2YGE1 AR PTHR48092:SF13 KNIRPS-RELATED PROTEIN-RELATED ANDROGEN RECEPTOR signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 sex differentiation#GO:0007548;response to hormone#GO:0009725;response to chemical#GO:0042221;response to lipid#GO:0033993;development of primary sexual characteristics#GO:0045137;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;reproductive structure development#GO:0048608;cellular response to endogenous stimulus#GO:0071495;gamete generation#GO:0007276;positive regulation of metabolic process#GO:0009893;hormone-mediated signaling pathway#GO:0009755;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;gonad development#GO:0008406;nuclear receptor-mediated signaling pathway#GO:0141193;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;male sex differentiation#GO:0046661;development of primary male sexual characteristics#GO:0046546;regulation of gene expression#GO:0010468;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;system development#GO:0048731;intracellular signal transduction#GO:0035556;reproductive system development#GO:0061458;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;male gonad development#GO:0008584;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to lipid#GO:0071396;multicellular organism development#GO:0007275;cellular response to steroid hormone stimulus#GO:0071383;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of biosynthetic process#GO:0009889;steroid hormone receptor signaling pathway#GO:0043401;cellular response to stimulus#GO:0051716;intracellular receptor signaling pathway#GO:0030522;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;response to steroid hormone#GO:0048545;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>AR#P06774 GORGO|Ensembl=ENSGGOG00000007691.3|UniProtKB=G3QXI7 G3QXI7 CACHD1 PTHR10166:SF68 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VWFA AND CACHE DOMAIN-CONTAINING PROTEIN 1 voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704 transporter#PC00227;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000008890.3|UniProtKB=G3RE65 G3RE65 RAB3A PTHR47980:SF9 LD44762P RAS-RELATED PROTEIN RAB-3A binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;calcium-ion regulated exocytosis#GO:0017156;neurogenesis#GO:0022008;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;axon development#GO:0061564;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;sexual reproduction#GO:0019953;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;system development#GO:0048731;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;secretion#GO:0046903;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;reproductive process#GO:0022414;anterograde trans-synaptic signaling#GO:0098916;neuron differentiation#GO:0030182;acrosomal vesicle exocytosis#GO:0060478;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;neuron projection development#GO:0031175;single fertilization#GO:0007338;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;vesicle-mediated transport#GO:0016192;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;secretion by cell#GO:0032940;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular localization#GO:0051641;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;acrosome reaction#GO:0007340;cellular component organization#GO:0016043;signaling#GO:0023052;export from cell#GO:0140352;fertilization#GO:0009566;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902 cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular vesicle#GO:0097708;intracellular organelle#GO:0043229;endosome#GO:0005768;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;plasma membrane#GO:0005886;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;axon#GO:0030424 Synaptic vesicle trafficking#P05734>Rab3A#P05780 GORGO|Ensembl=ENSGGOG00000002412.3|UniProtKB=G3SK63 G3SK63 FAM124A PTHR14715:SF4 FAM124 DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN FAM124A GORGO|Ensembl=ENSGGOG00000001558.3|UniProtKB=G3QGS3 G3QGS3 IGFBP3 PTHR11551:SF3 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 p53 pathway#P00059>IGF-BP3#G04691 GORGO|Ensembl=ENSGGOG00000043054.1|UniProtKB=A0A2I2ZWZ2 A0A2I2ZWZ2 PTHR24072:SF136 RHO FAMILY GTPASE CELL DIVISION CONTROL PROTEIN 42 HOMOLOG protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;localization#GO:0051179;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;regulation of cell projection assembly#GO:0060491;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;transport#GO:0006810;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;regulation of filopodium assembly#GO:0051489;actin filament organization#GO:0007015 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Cdc42#P00938;Gonadotropin-releasing hormone receptor pathway#P06664>Cdc42#P06743;CCKR signaling map#P06959>CDC42-GDP#P07044;Ras Pathway#P04393>Cdc42#P04569;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;CCKR signaling map#P06959>CDC42-GTP#P07155;T cell activation#P00053>cdc42#P01333;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Huntington disease#P00029>Rac#P00775;Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349;p38 MAPK pathway#P05918>Cdc42#P06041;Axon guidance mediated by netrin#P00009>cdc42#P00364 GORGO|Ensembl=ENSGGOG00000015402.3|UniProtKB=G3RHA6 G3RHA6 PEX11B PTHR12652:SF7 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11B peroxisome organization#GO:0007031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285 intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777 GORGO|Ensembl=ENSGGOG00000015774.4|UniProtKB=G3RI95 G3RI95 THEMIS PTHR15215:SF1 CABIT DOMAIN-CONTAINING PROTEIN PROTEIN THEMIS regulation of immune response#GO:0050776;immune system process#GO:0002376;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;T cell receptor signaling pathway#GO:0050852;immune response-activating signaling pathway#GO:0002757;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000026708.2|UniProtKB=G3SHK8 G3SHK8 GPR35 PTHR24232:SF54 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 35 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000013887.3|UniProtKB=G3RPI7 G3RPI7 SRD5A2 PTHR10556:SF37 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 system development#GO:0048731;reproductive system development#GO:0061458;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;hormone biosynthetic process#GO:0042446;reproductive process#GO:0022414;reproductive structure development#GO:0048608;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;multicellular organism development#GO:0007275;steroid biosynthetic process#GO:0006694;animal organ development#GO:0048513;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;lipid metabolic process#GO:0006629;male sex differentiation#GO:0046661;development of primary male sexual characteristics#GO:0046546;metabolic process#GO:0008152;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gonad development#GO:0008406;hormone metabolic process#GO:0042445;multicellular organismal process#GO:0032501;lipid biosynthetic process#GO:0008610;male gonad development#GO:0008584;cellular process#GO:0009987;sex differentiation#GO:0007548 neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell body#GO:0044297 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000014970.3|UniProtKB=A0A2I2ZL66 A0A2I2ZL66 PTHR10913:SF45 FOLLISTATIN-RELATED AGRIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000010171.3|UniProtKB=G3R3Z1 G3R3Z1 LRP1 PTHR46513:SF37 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LDL RECEPTOR RELATED PROTEIN 1-RELATED transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016985.3|UniProtKB=G3SIH2 G3SIH2 HGSNAT PTHR31061:SF37 LD22376P HEPARAN-ALPHA-GLUCOSAMINIDE N-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407 glycoprotein metabolic process#GO:0009100;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000026057.2|UniProtKB=G3RUK5 G3RUK5 KIF1B PTHR24115:SF328 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1B hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817 microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;cytosolic transport#GO:0016482;axonal transport#GO:0098930;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;retrograde axonal transport#GO:0008090;localization#GO:0051179;cellular localization#GO:0051641;axo-dendritic transport#GO:0008088;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule#GO:0005874;vesicle#GO:0031982;intracellular vesicle#GO:0097708;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000008477.3|UniProtKB=G3QZH6 G3QZH6 TPPP3 PTHR12932:SF16 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 3 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of protein polymerization#GO:0032273;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;microtubule bundle formation#GO:0001578;positive regulation of cellular component organization#GO:0051130;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000023021.2|UniProtKB=A0A2I2Z7V0 A0A2I2Z7V0 C8H10orf53 PTHR28448:SF1 UPF0728 PROTEIN C10ORF53 UPF0728 PROTEIN C10ORF53 GORGO|Ensembl=ENSGGOG00000043074.1|UniProtKB=A0A2I2ZB32 A0A2I2ZB32 PTHR13112:SF13 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN UPF3 DOMAIN-CONTAINING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;RNA binding#GO:0003723;DNA binding#GO:0003677 nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;positive regulation of macromolecule metabolic process#GO:0010604;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;positive regulation of protein metabolic process#GO:0051247;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000027671.2|UniProtKB=G3RZ14 G3RZ14 TAAR1 PTHR24249:SF415 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000044220.1|UniProtKB=A0A2I2Z1G4 A0A2I2Z1G4 PTHR13539:SF3 CALMODULIN-LYSINE N-METHYLTRANSFERASE CALMODULIN-LYSINE N-METHYLTRANSFERASE protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278 protein modifying enzyme#PC00260 GORGO|Gene=ALDH5A1|UniProtKB=Q6A2H1 Q6A2H1 ALDH5A1 PTHR43353:SF14 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481;Aminobutyrate degradation#P02726>Succinate semi-aldehyde dehydrogenase#P02824 GORGO|Ensembl=ENSGGOG00000016788.3|UniProtKB=G3RKU8 G3RKU8 VPS37C PTHR13678:SF8 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37C establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;cellular localization#GO:0051641;protein transport#GO:0015031;establishment of protein localization to membrane#GO:0090150;protein targeting to vacuole#GO:0006623;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;protein targeting to membrane#GO:0006612;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;protein localization to vacuole#GO:0072665;localization within membrane#GO:0051668;localization#GO:0051179;protein metabolic process#GO:0019538;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000005254.3|UniProtKB=A0A2I2Y999 A0A2I2Y999 ARL2 PTHR45697:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2 purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000006240.3|UniProtKB=A0A2I2Y4N6 A0A2I2Y4N6 WIPI2 PTHR11227:SF27 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;polysaccharide catabolic process#GO:0000272;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;energy derivation by oxidation of organic compounds#GO:0015980;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000814.3|UniProtKB=G3QEV1 G3QEV1 SEMA4A PTHR11036:SF15 SEMAPHORIN SEMAPHORIN-4A signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;chemotaxis#GO:0006935;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;locomotion#GO:0040011 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000002778.3|UniProtKB=G3QJX7 G3QJX7 CACNG3 PTHR12107:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-3 SUBUNIT voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215 regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;positive regulation of synaptic transmission#GO:0050806;localization within membrane#GO:0051668;regulation of signaling#GO:0023051;nervous system process#GO:0050877;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;localization#GO:0051179;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transmission of nerve impulse#GO:0019226;system process#GO:0003008 plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000013244.3|UniProtKB=A0A2I2YLB9 A0A2I2YLB9 ADARB1 PTHR10910:SF58 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN DOUBLE-STRANDED RNA-SPECIFIC EDITASE 1 catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;RNA binding#GO:0003723;hydrolase activity#GO:0016787;tRNA-specific adenosine deaminase activity#GO:0008251;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;adenosine to inosine editing#GO:0006382;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;base conversion or substitution editing#GO:0016553;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000044016.1|UniProtKB=A0A2I2YUI1 A0A2I2YUI1 SHISAL2A PTHR31395:SF3 SHISA PROTEIN SHISA-LIKE-2A scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015359.3|UniProtKB=A0A2I2ZCG1 A0A2I2ZCG1 PRDM10 PTHR24403:SF48 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 10 double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000003895.3|UniProtKB=G3SH85 G3SH85 ARL3 PTHR45697:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000049.4|UniProtKB=G3QCV0 G3QCV0 CWF19L2 PTHR12072:SF5 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 2 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008055.3|UniProtKB=G3QYE8 G3QYE8 HMBS PTHR11557:SF0 PORPHOBILINOGEN DEAMINASE PORPHOBILINOGEN DEAMINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 porphyrin-containing compound biosynthetic process#GO:0006779;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;deaminase#PC00088 Heme biosynthesis#P02746>Hydroxymethylbilane synthase#P02983 GORGO|Ensembl=ENSGGOG00000037113.1|UniProtKB=A0A2I2ZY75 A0A2I2ZY75 SDHAF4 PTHR28524:SF3 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000005090.3|UniProtKB=G3QQW8 G3QQW8 PTBP1 PTHR15592:SF19 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of cell differentiation#GO:0045595;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000015187.3|UniProtKB=G3RGR2 G3RGR2 SLC22A7 PTHR24064:SF33 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 7 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000005892.3|UniProtKB=G3QSW8 G3QSW8 PTHR10993:SF7 OCTANOYLTRANSFERASE OCTANOYL-[ACYL-CARRIER-PROTEIN]:PROTEIN N-OCTANOYLTRANSFERASE LIPT2, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 transferase#PC00220 Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003 GORGO|Ensembl=ENSGGOG00000011716.3|UniProtKB=G3S874 G3S874 POM121C PTHR23193:SF5 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR ENVELOPE PORE MEMBRANE PROTEIN POM 121C-RELATED structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010824.3|UniProtKB=G3R5I3 G3R5I3 SLC6A14 PTHR11616:SF286 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT NEUTRAL AND BASIC AMINO ACID TRANSPORTER B(0+) secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;branched-chain amino acid transmembrane transporter activity#GO:0015658;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;quaternary ammonium group transmembrane transporter activity#GO:0015651;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;sodium ion transport#GO:0006814;localization#GO:0051179;monoatomic cation transport#GO:0006812;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000025206.2|UniProtKB=G3RV35 G3RV35 PTHR43856:SF3 CARDIOLIPIN HYDROLASE MITOCHONDRIAL CARDIOLIPIN HYDROLASE phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;lipase activity#GO:0016298 metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;oogenesis#GO:0048477;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;cell cycle#GO:0007049;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;germ cell development#GO:0007281;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000038784.1|UniProtKB=A0A2I2Y7G6 A0A2I2Y7G6 PTHR13381:SF2 RNA POLYMERASE II HOLOENZYME COMPONENT SRB7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004171.3|UniProtKB=A0A2I2YEF4 A0A2I2YEF4 SUCO PTHR12953:SF10 MEMBRANE PROTEIN CH1 RELATED SUN DOMAIN-CONTAINING OSSIFICATION FACTOR regulation of multicellular organismal process#GO:0051239;regulation of tissue remodeling#GO:0034103;biological regulation#GO:0065007;regulation of bone remodeling#GO:0046850;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000022575.2|UniProtKB=G3RR13 G3RR13 PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3B enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000023300.2|UniProtKB=G3SBH0 G3SBH0 LOC101148803 PTHR19297:SF178 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 7-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000008463.3|UniProtKB=G3QZG3 G3QZG3 ANGPTL5 PTHR19143:SF185 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 5 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000037922.1|UniProtKB=A0A2I2Y2Y9 A0A2I2Y2Y9 CHST14 PTHR12137:SF66 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 14 transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000008098.3|UniProtKB=G3S245 G3S245 CDC37 PTHR12800:SF3 CDC37-RELATED HSP90 CO-CHAPERONE CDC37 protein binding#GO:0005515;binding#GO:0005488;heat shock protein binding#GO:0031072 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of protein stability#GO:0031647;regulation of response to cytokine stimulus#GO:0060759;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;gene expression#GO:0010467;protein maturation#GO:0051604;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;protein stabilization#GO:0050821;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of innate immune response#GO:0045088;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of response to biotic stimulus#GO:0002831;protein folding#GO:0006457;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein folding chaperone complex#GO:0101031 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000025505.2|UniProtKB=G3RPE0 G3RPE0 SERPINB5 PTHR11461:SF55 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B5 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 p53 pathway#P00059>Maspin#G01569 GORGO|Ensembl=ENSGGOG00000012135.3|UniProtKB=G3RS08 G3RS08 MYC PTHR45851:SF1 MYC PROTO-ONCOGENE MYC PROTO-ONCOGENE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CCKR signaling map#P06959>MYC#G06979;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;PDGF signaling pathway#P00047>c-Myc#P01172;Oxidative stress response#P00046>Myc#P01124;p53 pathway feedback loops 2#P04398>Myc#P04649;CCKR signaling map#P06959>MYC#G07272;Interleukin signaling pathway#P00036>c-Myc#P00995 GORGO|Ensembl=ENSGGOG00000006071.3|UniProtKB=G3QTC4 G3QTC4 CINP PTHR15827:SF2 CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN DNA replication#GO:0006260;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 Cell cycle#P00013>Cdk2#P00485 GORGO|Ensembl=ENSGGOG00000025268.2|UniProtKB=A0A2I2ZKR6 A0A2I2ZKR6 PTHR10510:SF15 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A3, MITOCHONDRIAL-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;respiratory chain complex#GO:0098803;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000007562.3|UniProtKB=A0A2I2YFA7 A0A2I2YFA7 PPP5C PTHR45668:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 5 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000002529.3|UniProtKB=G3QJA5 G3QJA5 MTRF1 PTHR43804:SF1 LD18447P PEPTIDE CHAIN RELEASE FACTOR 1, MITOCHONDRIAL macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;protein-containing complex disassembly#GO:0032984;translational termination#GO:0006415;translation#GO:0006412;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translation release factor#PC00225;translational protein#PC00263;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000000057.4|UniProtKB=G3QCV6 G3QCV6 LOC101151965 PTHR24300:SF360 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C19 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular response to xenobiotic stimulus#GO:0071466;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;response to xenobiotic stimulus#GO:0009410;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;olefinic compound metabolic process#GO:0120254;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000000757.3|UniProtKB=A0A2I2ZLC4 A0A2I2ZLC4 SLC12A1 PTHR11827:SF93 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 1 active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000027838.2|UniProtKB=G3RRK7 G3RRK7 UBR7 PTHR13513:SF9 E3 UBIQUITIN-PROTEIN LIGASE UBR7 E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009965.3|UniProtKB=G3R3A9 G3R3A9 GRIN2B PTHR18966:SF382 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2B transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;voltage-gated monoatomic ion channel activity#GO:0005244 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;chemical synaptic transmission, postsynaptic#GO:0099565;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of postsynaptic membrane potential#GO:0060078;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;system process#GO:0003008;regulation of synaptic plasticity#GO:0048167;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;nervous system process#GO:0050877;positive regulation of synaptic transmission#GO:0050806;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;synaptic signaling#GO:0099536 organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NR2B#P01007;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024 GORGO|Ensembl=ENSGGOG00000024754.2|UniProtKB=G3S859 G3S859 ATPAF1 PTHR13126:SF0 CHAPERONE ATP11 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000001560.3|UniProtKB=G3QGS5 G3QGS5 MX1 PTHR11566:SF217 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MX1 microtubule binding#GO:0008017;GTPase activity#GO:0003924;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;cellular component organization#GO:0016043;defense response to virus#GO:0051607;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;response to virus#GO:0009615;localization#GO:0051179;organelle localization#GO:0051640;response to external biotic stimulus#GO:0043207;synaptic vesicle endocytosis#GO:0048488;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;defense response#GO:0006952;response to external stimulus#GO:0009605;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;synaptic vesicle recycling#GO:0036465;response to other organism#GO:0051707;membrane organization#GO:0061024;vesicle localization#GO:0051648 intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015355.3|UniProtKB=A0A2I2ZFL3 A0A2I2ZFL3 HOOK1 PTHR18947:SF36 HOOK PROTEINS PROTEIN HOOK HOMOLOG 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cellular component organization#GO:0016043;cytoplasmic microtubule organization#GO:0031122;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006657.3|UniProtKB=A0A2I2Z0E7 A0A2I2Z0E7 GTF2F2 PTHR10445:SF0 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIFbeta#P00667;Transcription regulation by bZIP transcription factor#P00055>TFIIFbeta#P01396 GORGO|Ensembl=ENSGGOG00000001500.3|UniProtKB=A0A2I2YBJ3 A0A2I2YBJ3 PLEKHH1 PTHR22903:SF4 PLEKHH PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 1 GORGO|Ensembl=ENSGGOG00000004743.3|UniProtKB=G3RUB3 G3RUB3 PTHR10005:SF8 SKI ONCOGENE-RELATED SKI FAMILY TRANSCRIPTIONAL COREPRESSOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of BMP signaling pathway#GO:0030510;negative regulation of macromolecule metabolic process#GO:0010605 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000011263.3|UniProtKB=G3R6M1 G3R6M1 ARF1 PTHR11711:SF357 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 guanyl nucleotide binding#GO:0019001;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 GORGO|Ensembl=ENSGGOG00000013920.3|UniProtKB=G3RDH3 G3RDH3 CELF4 PTHR24012:SF721 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 4 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003890.3|UniProtKB=G3QMT1 G3QMT1 RABGAP1 PTHR47219:SF6 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE RAB GTPASE-ACTIVATING PROTEIN 1 binding#GO:0005488;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000043453.1|UniProtKB=A0A2I2Z366 A0A2I2Z366 PTHR14399:SF4 P53-INDUCED PROTEIN RELATED P53 APOPTOSIS EFFECTOR RELATED TO PMP-22 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 p53 pathway#P00059>PERP#G01565 GORGO|Ensembl=ENSGGOG00000009750.3|UniProtKB=G3R2R4 G3R2R4 PDIA2 PTHR18929:SF93 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A2 catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;response to stimulus#GO:0050896;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000013962.3|UniProtKB=G3RDL9 G3RDL9 PTHR23412:SF6 STEREOCILIN RELATED MESOTHELIN cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000024161.2|UniProtKB=G3S6C8 G3S6C8 PTHR12146:SF10 40S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN ES10 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000037094.1|UniProtKB=G3S4Z9 G3S4Z9 LOC101131885 PTHR23430:SF220 HISTONE H2A HISTONE H2A TYPE 3 structural molecule activity#GO:0005198 heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000036144.1|UniProtKB=A0A2I2ZXB6 A0A2I2ZXB6 PTHR44305:SF24 SI:DKEY-192D15.2-RELATED TYROSINE-PROTEIN KINASE C03B1.5-RELATED GORGO|Ensembl=ENSGGOG00000007681.3|UniProtKB=G3QXH7 G3QXH7 MTIF2 PTHR43381:SF20 TRANSLATION INITIATION FACTOR IF-2-RELATED TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000017087.3|UniProtKB=G3RLL8 G3RLL8 PLA2G6 PTHR24139:SF34 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 85_88 KDA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 lipase activity#GO:0016298;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;carboxylic ester hydrolase activity#GO:0052689;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787;deacylase activity#GO:0160215;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of biosynthetic process#GO:0009889;organophosphate metabolic process#GO:0019637;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;regulation of lipid biosynthetic process#GO:0046890;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;regulation of macromolecule metabolic process#GO:0060255;phosphatidylglycerol metabolic process#GO:0046471;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;regulation of cellular component biogenesis#GO:0044087 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 lipase#PC00143;phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738 GORGO|Ensembl=ENSGGOG00000040731.1|UniProtKB=G3RU19 G3RU19 LOC101154451 PTHR23428:SF77 HISTONE H2B HISTONE H2B TYPE 1-A chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000042542.1|UniProtKB=A0A2I2Y6M5 A0A2I2Y6M5 RHOB PTHR24072:SF0 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOB catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 signaling#GO:0023052;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein#PC00020;small GTPase#PC00208 Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Integrin signalling pathway#P00034>Rho#P00948;Ras Pathway#P04393>Rho#P04578;PDGF signaling pathway#P00047>Ras#P01154;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507;Angiogenesis#P00005>GTPase#P00254 GORGO|Ensembl=ENSGGOG00000043134.1|UniProtKB=A0A2I2Z967 A0A2I2Z967 FLYWCH2 PTHR31665:SF0 FLYWCH FAMILY MEMBER 2-RELATED FLYWCH FAMILY MEMBER 2 GORGO|Gene=NDUFB1|UniProtKB=Q0MQC5 Q0MQC5 NDUFB1 PTHR15222:SF5 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000004649.3|UniProtKB=G3QPQ5 G3QPQ5 GSK3A PTHR24057:SF14 GLYCOGEN SYNTHASE KINASE-3 ALPHA GLYCOGEN SYNTHASE KINASE-3 ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cytoskeleton organization#GO:0051493;negative regulation of TOR signaling#GO:0032007;cellular response to peptide hormone stimulus#GO:0071375;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;negative regulation of Wnt signaling pathway#GO:0030178;cellular response to nitrogen compound#GO:1901699;regulation of signal transduction#GO:0009966;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;positive regulation of proteasomal protein catabolic process#GO:1901800;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;regulation of neuron apoptotic process#GO:0043523;positive regulation of autophagy#GO:0010508;response to hormone#GO:0009725;regulation of protein metabolic process#GO:0051246;regulation of TOR signaling#GO:0032006;response to chemical#GO:0042221;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of microtubule-based process#GO:0032886;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;positive regulation of neuron apoptotic process#GO:0043525;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cellular response to hormone stimulus#GO:0032870;regulation of Wnt signaling pathway#GO:0030111;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;insulin receptor signaling pathway#GO:0008286;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;negative regulation of signal transduction#GO:0009968;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;nucleus#GO:0005634;neuron projection#GO:0043005;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167 Ras Pathway#P04393>GSK3#P04546;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GSK#P00714;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PDGF signaling pathway#P00047>GSK3#P01153 GORGO|Ensembl=ENSGGOG00000011348.3|UniProtKB=G3R6V6 G3R6V6 TEX14 PTHR23060:SF1 TESTIS EXPRESSED GENE 14 INACTIVE SERINE_THREONINE-PROTEIN KINASE TEX14 regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;male gamete generation#GO:0048232;regulation of mitotic cell cycle#GO:0007346;mitotic sister chromatid segregation#GO:0000070;intracellular signal transduction#GO:0035556;organelle fission#GO:0048285;localization#GO:0051179;cell communication#GO:0007154;organelle localization#GO:0051640;negative regulation of chromosome organization#GO:2001251;reproductive process#GO:0022414;mitotic sister chromatid separation#GO:0051306;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;chromosome separation#GO:0051304;negative regulation of cell cycle#GO:0045786;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;metaphase chromosome alignment#GO:0051310;chromosome localization#GO:0050000;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;mitotic spindle assembly checkpoint signaling#GO:0007094;attachment of spindle microtubules to kinetochore#GO:0008608;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;extracellular structure organization#GO:0043062;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;gamete generation#GO:0007276;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;meiotic nuclear division#GO:0140013;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic sister chromatid segregation#GO:0033047;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular component organization or biogenesis#GO:0071840;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;meiotic cell cycle#GO:0051321;male meiotic nuclear division#GO:0007140;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;nuclear division#GO:0000280;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519 chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;midbody#GO:0030496;kinetochore#GO:0000776;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002098.3|UniProtKB=G3QI64 G3QI64 CHRND PTHR18945:SF61 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT DELTA extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;nervous system process#GO:0050877;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of biological process#GO:0050789;muscle system process#GO:0003012;response to stimulus#GO:0050896;signaling#GO:0023052;skeletal muscle contraction#GO:0003009;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;trans-synaptic signaling#GO:0099537;neuromuscular process#GO:0050905;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;membrane depolarization#GO:0051899;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;muscle contraction#GO:0006936;transport#GO:0006810;establishment of localization#GO:0051234;system process#GO:0003008;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220 cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>delta#P01092;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 GORGO|Ensembl=ENSGGOG00000022441.2|UniProtKB=G3RTK0 G3RTK0 LOC101144131 PTHR11595:SF53 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-BETA guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000006085.3|UniProtKB=G3QTE3 G3QTE3 SLC7A10 PTHR11785:SF73 AMINO ACID TRANSPORTER ASC-TYPE AMINO ACID TRANSPORTER 1 neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;alanine transport#GO:0032328;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000005210.3|UniProtKB=A0A2I2YJM1 A0A2I2YJM1 TPPP2 PTHR12932:SF21 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 2 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;positive regulation of cellular component organization#GO:0051130;microtubule bundle formation#GO:0001578 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000002641.3|UniProtKB=A0A2I2YL98 A0A2I2YL98 LOC101137639 PTHR12850:SF19 40S RIBOSOMAL PROTEIN S25 40S RIBOSOMAL PROTEIN S25 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012278.3|UniProtKB=G3R999 G3R999 PTHR22797:SF37 CARD6/NUCLEOLAR PROTEIN 3 NUCLEOLAR PROTEIN 3 GORGO|Ensembl=ENSGGOG00000007041.3|UniProtKB=A0A2I2YXW0 A0A2I2YXW0 OSCP1 PTHR21439:SF0 OXIDORED-NITRO DOMAIN-CONTAINING PROTEIN PROTEIN OSCP1 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014869.3|UniProtKB=G3RWM9 G3RWM9 PKHD1L1 PTHR46769:SF3 POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1 FIBROCYSTIN-L GORGO|Ensembl=ENSGGOG00000037980.1|UniProtKB=A0A2I2ZDG4 A0A2I2ZDG4 SLC7A1 PTHR43243:SF28 INNER MEMBRANE TRANSPORTER YGJI-RELATED HIGH AFFINITY CATIONIC AMINO ACID TRANSPORTER 1 amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;amino acid transporter#PC00046 GORGO|Ensembl=ENSGGOG00000027925.2|UniProtKB=G3S9P8 G3S9P8 PTHR22747:SF28 NUCLEOPLASMIN NUCLEOPHOSMIN binding#GO:0005488;nucleic acid binding#GO:0003676;histone binding#GO:0042393;chromatin binding#GO:0003682;RNA binding#GO:0003723;protein binding#GO:0005515 regulation of gene expression#GO:0010468;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;transport#GO:0006810;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nuclear transport#GO:0051169;nuclear export#GO:0051168;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;regulation of DNA-templated transcription#GO:0006355;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cell cycle process#GO:0010564;positive regulation of macromolecule metabolic process#GO:0010604;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular localization#GO:0051641;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;regulation of cell cycle#GO:0051726;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;ribosomal large subunit export from nucleus#GO:0000055;cellular component organization#GO:0016043 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000007818.3|UniProtKB=G3QXT2 G3QXT2 SLC5A7 PTHR45897:SF2 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH AFFINITY CHOLINE TRANSPORTER 1 symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;transport#GO:0006810;neuromuscular synaptic transmission#GO:0007274;metabolic process#GO:0008152;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;nitrogen compound transport#GO:0071705 cell body#GO:0044297;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;perikaryon#GO:0043204 transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072 GORGO|Ensembl=ENSGGOG00000038832.1|UniProtKB=G3R3Q2 G3R3Q2 PTHR24384:SF104 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 714 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000041565.1|UniProtKB=A0A2I2ZPZ6 A0A2I2ZPZ6 PTHR23428:SF250 HISTONE H2B HISTONE H2B TYPE 1-D humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000007682.3|UniProtKB=G3S7E9 G3S7E9 ALDH3A1 PTHR43570:SF15 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE, DIMERIC NADP-PREFERRING oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000025663.2|UniProtKB=G3RZK8 G3RZK8 ACRBP PTHR21362:SF1 ACROSIN-BINDING PROTEIN ACROSIN-BINDING PROTEIN cellular component assembly#GO:0022607;male gamete generation#GO:0048232;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;anatomical structure formation involved in morphogenesis#GO:0048646;vesicle organization#GO:0016050;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;spermatogenesis#GO:0007283;cell differentiation#GO:0030154;gamete generation#GO:0007276;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;germ cell development#GO:0007281;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;acrosome assembly#GO:0001675;spermatid development#GO:0007286 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669 GORGO|Ensembl=ENSGGOG00000028381.2|UniProtKB=A0A2I2YNX4 A0A2I2YNX4 RBBP8 PTHR15107:SF4 RETINOBLASTOMA BINDING PROTEIN 8 DNA ENDONUCLEASE RBBP8 damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 cellular response to stress#GO:0033554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via single-strand annealing#GO:0045002;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000006799.3|UniProtKB=G3QV91 G3QV91 VPS26B PTHR12233:SF5 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26B cytosolic transport#GO:0016482;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;retromer complex#GO:0030904;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000009841.3|UniProtKB=A0A2I2Y588 A0A2I2Y588 KCNIP3 PTHR23055:SF165 CALCIUM BINDING PROTEINS CALSENILIN sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;metal ion binding#GO:0046872;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;calcium ion binding#GO:0005509;potassium channel regulator activity#GO:0015459;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;cation binding#GO:0043169;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;channel regulator activity#GO:0016247;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;ion binding#GO:0043167;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transporter regulator activity#GO:0141108 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of monoatomic ion transport#GO:0043269;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of monoatomic cation transmembrane transport#GO:1904062;negative regulation of cellular process#GO:0048523;regulation of metal ion transport#GO:0010959;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of transmembrane transport#GO:0034762;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252 transporter complex#GO:1990351;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000022457.2|UniProtKB=G3S3L1 G3S3L1 FBXW12 PTHR44019:SF17 WD REPEAT-CONTAINING PROTEIN 55 F-BOX_WD REPEAT-CONTAINING PROTEIN 12 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000010645.3|UniProtKB=G3R526 G3R526 DNA2 PTHR36531:SF6 CRISPR-ASSOCIATED EXONUCLEASE CAS4 DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2 5'-3' exonuclease activity#GO:0008409;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;DNA catabolic process#GO:0006308;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 GORGO|Ensembl=ENSGGOG00000015848.3|UniProtKB=G3RIG1 G3RIG1 GDPD5 PTHR23344:SF6 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 2 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;regulation of cellular process#GO:0050794;regulation of neuron differentiation#GO:0045664;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000013162.3|UniProtKB=G3RBI0 G3RBI0 LOC101129370 PTHR46329:SF1 KILLER CELL LECTIN-LIKE RECEPTOR 2 KILLER CELL LECTIN-LIKE RECEPTOR, SUBFAMILY A, MEMBER 17 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016324.3|UniProtKB=G3RJN2 G3RJN2 SEMA3C PTHR11036:SF25 SEMAPHORIN SEMAPHORIN-3C protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;mesenchyme development#GO:0060485;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;axon development#GO:0061564;axon guidance#GO:0007411;stem cell differentiation#GO:0048863;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;tissue development#GO:0009888;cell migration#GO:0016477;neural crest cell development#GO:0014032;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;stem cell development#GO:0048864;chemotaxis#GO:0006935;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;locomotion#GO:0040011;mesenchymal cell differentiation#GO:0048762;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neural crest cell differentiation#GO:0014033;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;neural crest cell migration#GO:0001755;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;taxis#GO:0042330;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000013417.3|UniProtKB=G3RC75 G3RC75 KIF5B PTHR24115:SF513 KINESIN-RELATED KINESIN-1 HEAVY CHAIN microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774 axonal transport#GO:0098930;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;anterograde axonal transport#GO:0008089;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;synaptic vesicle transport#GO:0048489;axo-dendritic transport#GO:0008088;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384 supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000013860.3|UniProtKB=G3RM97 G3RM97 GPATCH8 PTHR17614:SF11 ZINC FINGER-CONTAINING G PATCH DOMAIN-CONTAINING PROTEIN 8 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000006350.3|UniProtKB=G3QU26 G3QU26 PTHR10353:SF336 GLYCOSYL HYDROLASE LACTASE-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;beta-glucosidase activity#GO:0008422;glucosidase activity#GO:0015926;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;glycosidase#PC00110;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000012615.3|UniProtKB=G3RA48 G3RA48 CACNG7 PTHR12107:SF12 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-7 SUBUNIT molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel regulator activity#GO:0016247;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transporter regulator activity#GO:0141108;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;localization#GO:0051179;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological quality#GO:0065008;positive regulation of synaptic transmission#GO:0050806;nervous system process#GO:0050877;regulation of signaling#GO:0023051;localization within membrane#GO:0051668;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of biological process#GO:0050789 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000023610.2|UniProtKB=G3RTM4 G3RTM4 KLK3 PTHR24271:SF73 KALLIKREIN-RELATED PROSTATE-SPECIFIC ANTIGEN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 zymogen activation#GO:0031638;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;proteolysis#GO:0006508;circulatory system process#GO:0003013;biosynthetic process#GO:0009058;biological regulation#GO:0065007;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;system process#GO:0003008;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000000040.3|UniProtKB=G3QCU1 G3QCU1 TMEM222 PTHR20921:SF0 TRANSMEMBRANE PROTEIN 222 TRANSMEMBRANE PROTEIN 222 GORGO|Ensembl=ENSGGOG00000041651.1|UniProtKB=A0A2I2Z2A7 A0A2I2Z2A7 SLC1A2 PTHR11958:SF93 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 2 amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;sodium:dicarboxylate symporter activity#GO:0017153;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;L-glutamate import#GO:0051938;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;aspartate transmembrane transport#GO:0015810;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 GORGO|Ensembl=ENSGGOG00000016004.3|UniProtKB=G3RIU8 G3RIU8 PGM1 PTHR22573:SF60 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE-1 isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;intramolecular phosphotransferase activity#GO:0016868 carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 mutase#PC00160;metabolite interconversion enzyme#PC00262;isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000024356.2|UniProtKB=G3SFN8 G3SFN8 BTBD19 PTHR46965:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 19 BTB_POZ DOMAIN-CONTAINING PROTEIN 19 GORGO|Ensembl=ENSGGOG00000024133.2|UniProtKB=A0A2I2Y4E9 A0A2I2Y4E9 PTHR48094:SF10 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED PARKINSON DISEASE PROTEIN 7 HOMOLOG catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;oxidoreductase activity#GO:0016491;hydro-lyase activity#GO:0016836;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;response to oxidative stress#GO:0006979;monocarboxylic acid biosynthetic process#GO:0072330;cellular response to oxygen-containing compound#GO:1901701;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;response to stress#GO:0006950;biosynthetic process#GO:0009058;detoxification#GO:0098754;aldehyde catabolic process#GO:0046185;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;cellular detoxification of aldehyde#GO:0110095;carboxylic acid metabolic process#GO:0019752;ketone metabolic process#GO:0042180;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;response to toxic substance#GO:0009636 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000015572.3|UniProtKB=G3RHR3 G3RHR3 TMEM207 PTHR36467:SF1 TRANSMEMBRANE PROTEIN 207 TRANSMEMBRANE PROTEIN 207 GORGO|Ensembl=ENSGGOG00000004484.3|UniProtKB=G3QPB1 G3QPB1 HR PTHR12549:SF4 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE HAIRLESS demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;chromatin DNA binding#GO:0031490;histone demethylase activity#GO:0032452;DNA binding#GO:0003677;histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000026916.2|UniProtKB=G3SFV2 G3SFV2 PTHR23420:SF17 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;purine-containing compound metabolic process#GO:0072521 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000012914.3|UniProtKB=G3RAW4 G3RAW4 LSM4 PTHR23338:SF16 SMALL NUCLEAR RIBONUCLEOPROTEIN SM U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM4 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;P-body assembly#GO:0033962;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;organelle organization#GO:0006996;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;P-body#GO:0000932;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000000933.3|UniProtKB=G3QF56 G3QF56 BAG4 PTHR12329:SF10 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 4 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;regulation of protein stability#GO:0031647 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cytosol#GO:0005829;nucleus#GO:0005634 chaperone#PC00072 Apoptosis signaling pathway#P00006>SODD#P00320 GORGO|Ensembl=ENSGGOG00000014998.3|UniProtKB=A0A2I2YDA9 A0A2I2YDA9 PTPRO PTHR47028:SF1 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE O RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE O phosphoprotein phosphatase activity#GO:0004721;Wnt-protein binding#GO:0017147;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;hydrolase activity#GO:0016787;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;cell adhesion molecule binding#GO:0050839;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 negative regulation of signal transduction#GO:0009968;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;neuron projection development#GO:0031175;renal system development#GO:0072001;kidney development#GO:0001822;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;neuron development#GO:0048666;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;epithelial cell differentiation#GO:0030855;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;anatomical structure development#GO:0048856;system development#GO:0048731 cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005393.3|UniProtKB=G3QRM0 G3QRM0 OTOS PTHR35073:SF1 OTOSPIRALIN OTOSPIRALIN nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605 GORGO|Ensembl=ENSGGOG00000016144.3|UniProtKB=G3RJ74 G3RJ74 GIPR PTHR45620:SF5 PDF RECEPTOR-LIKE PROTEIN-RELATED GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025140.2|UniProtKB=G3RR19 G3RR19 SDHAF2 PTHR12469:SF2 PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL aerobic respiration#GO:0009060;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic electron transport chain#GO:0019646;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex II assembly#GO:0034553;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;tricarboxylic acid cycle#GO:0006099;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000004684.3|UniProtKB=G3S961 G3S961 LMOD2 PTHR10901:SF12 TROPOMODULIN LEIOMODIN-2 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;developmental process#GO:0032502;muscle contraction#GO:0006936;system process#GO:0003008;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;A band#GO:0031672;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;M band#GO:0031430;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000014977.3|UniProtKB=G3SER2 G3SER2 LIAS PTHR10949:SF0 LIPOYL SYNTHASE LIPOYL SYNTHASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Lipoate_biosynthesis#P02750>Lipoate synthase#P03004 GORGO|Ensembl=ENSGGOG00000002697.3|UniProtKB=G3QJQ6 G3QJQ6 ZFPL1 PTHR12981:SF0 ZINC FINGER PROTEIN-LIKE 1 ZINC FINGER PROTEIN-LIKE 1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000003126.3|UniProtKB=G3QKU2 G3QKU2 KRT5 PTHR45616:SF32 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 5 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;developmental process#GO:0032502;epidermis development#GO:0008544;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513 supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 GORGO|Gene=FPR2|UniProtKB=P79177 P79177 FPR2 PTHR24225:SF0 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;regulation of biological quality#GO:0065008;cell communication#GO:0007154;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000008491.3|UniProtKB=A0A2I2ZIB1 A0A2I2ZIB1 PTHR42748:SF16 NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER NMRA-LIKE FAMILY DOMAIN-CONTAINING PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016048.3|UniProtKB=G3SBS1 G3SBS1 ZNF384 PTHR24403:SF107 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 521-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000007009.3|UniProtKB=G3QVT0 G3QVT0 SMURF2 PTHR11254:SF300 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;protein metabolic process#GO:0019538;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;negative regulation of BMP signaling pathway#GO:0030514;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 TGF-beta signaling pathway#P00052>Smurfs#P01279;Ubiquitin proteasome pathway#P00060>E3#P01490 GORGO|Ensembl=ENSGGOG00000006404.3|UniProtKB=G3QU65 G3QU65 LRRN2 PTHR24366:SF92 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT NEURONAL PROTEIN 2 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000003389.4|UniProtKB=G3QLH9 G3QLH9 PRUNE2 PTHR12112:SF11 BNIP - RELATED PROTEIN PRUNE HOMOLOG 2 cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;programmed cell death#GO:0012501 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000026951.2|UniProtKB=G3SEM2 G3SEM2 PTHR12155:SF30 SCHLAFEN PROTEIN SLFN14 RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;protein-containing complex binding#GO:0044877;nuclease activity#GO:0004518;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000009570.3|UniProtKB=G3R2A5 G3R2A5 LOC101131035 PTHR11610:SF165 LIPASE PANCREATIC LIPASE-RELATED PROTEIN 2 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate catabolic process#GO:0046434 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000014425.3|UniProtKB=G3RS54 G3RS54 SUPT5H PTHR11125:SF7 SUPPRESSOR OF TY 5 TRANSCRIPTION ELONGATION FACTOR SPT5 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000025969.2|UniProtKB=G3RT06 G3RT06 PMM1 PTHR10466:SF1 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE 1 isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;intramolecular phosphotransferase activity#GO:0016868 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;protein N-linked glycosylation#GO:0006487;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 mutase#PC00160;metabolite interconversion enzyme#PC00262;isomerase#PC00135 Mannose metabolism#P02752>P-Mannose mutase#P03019 GORGO|Ensembl=ENSGGOG00000013584.3|UniProtKB=G3RW34 G3RW34 SLC12A5 PTHR11827:SF54 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 5 potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509 chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;neuron projection#GO:0043005;cell body#GO:0044297;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000014472.3|UniProtKB=G3REX2 G3REX2 SLC15A4 PTHR11654:SF80 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 4 aromatic amino acid transmembrane transporter activity#GO:0015173;basic amino acid transmembrane transporter activity#GO:0015174;carboxylic acid transmembrane transporter activity#GO:0046943;L-amino acid transmembrane transporter activity#GO:0015179;dipeptide transmembrane transporter activity#GO:0071916;oligopeptide transmembrane transporter activity#GO:0035673;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 import across plasma membrane#GO:0098739;cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;oligopeptide transport#GO:0006857;dipeptide transport#GO:0042938;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;localization#GO:0051179;amino acid transport#GO:0006865;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007003.3|UniProtKB=G3SHG2 G3SHG2 PTHR11353:SF26 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT DELTA cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 chaperonin-containing T-complex#GO:0005832;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein folding chaperone complex#GO:0101031;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000006192.3|UniProtKB=G3QTM3 G3QTM3 HSD11B1 PTHR44279:SF1 HYDROXYSTEROID (11-BETA) DEHYDROGENASE 1-LIKE B-RELATED 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;steroid binding#GO:0005496;lipid binding#GO:0008289;catalytic activity#GO:0003824;binding#GO:0005488;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 steroid metabolic process#GO:0008202;catabolic process#GO:0009056;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;steroid catabolic process#GO:0006706;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000026863.2|UniProtKB=G3SE77 G3SE77 SSBP2 PTHR12610:SF23 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000009682.3|UniProtKB=G3R2K4 G3R2K4 FOXN1 PTHR46721:SF1 FORKHEAD BOX PROTEIN N1 FORKHEAD BOX PROTEIN N1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000014402.3|UniProtKB=A0A2I2ZML1 A0A2I2ZML1 PLEKHG2 PTHR45924:SF3 FI17866P1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 2 enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000024599.2|UniProtKB=G3RPE5 G3RPE5 LOC101144634 PTHR47055:SF2 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 2-RELATED DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676 GORGO|Ensembl=ENSGGOG00000022923.2|UniProtKB=G3SB96 G3SB96 PTHR23266:SF298 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000026950.2|UniProtKB=G3S477 G3S477 SOS1 PTHR23113:SF168 GUANINE NUCLEOTIDE EXCHANGE FACTOR SON OF SEVENLESS HOMOLOG 1 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 CCKR signaling map#P06959>SOS1#P07061;B cell activation#P00010>SOS#P00379;Angiogenesis#P00005>SOS-1#P00193;PDGF signaling pathway#P00047>SOS#P01159;EGF receptor signaling pathway#P00018>SOS#P00558;Integrin signalling pathway#P00034>SOS#P00920;PI3 kinase pathway#P00048>SOS#P01185;FGF signaling pathway#P00021>SOS#P00641;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883;T cell activation#P00053>SOS#P01307;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Sos#P00850;Gonadotropin-releasing hormone receptor pathway#P06664>Sos#P06849;Ras Pathway#P04393>SOS#P04552;Interleukin signaling pathway#P00036>SOS#P00981 GORGO|Ensembl=ENSGGOG00000008494.3|UniProtKB=G3QZI8 G3QZI8 HMOX2 PTHR10720:SF2 HEME OXYGENASE HEME OXYGENASE 2 binding#GO:0005488;tetrapyrrole binding#GO:0046906;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 heme metabolic process#GO:0042168;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular process#GO:0009987;pigment metabolic process#GO:0042440;response to stress#GO:0006950;response to oxidative stress#GO:0006979;porphyrin-containing compound metabolic process#GO:0006778;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000023268.2|UniProtKB=A0A2I2ZU53 A0A2I2ZU53 PHF6 PTHR12420:SF15 PHD FINGER PROTEIN PHD FINGER PROTEIN 6 histone deacetylase binding#GO:0042826;protein binding#GO:0005515;enzyme binding#GO:0019899;histone binding#GO:0042393;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000015695.3|UniProtKB=A0A2I2YVZ8 A0A2I2YVZ8 LRP10 PTHR24270:SF17 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 10 cargo receptor activity#GO:0038024;low-density lipoprotein particle receptor activity#GO:0005041 lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000012775.3|UniProtKB=G3RAJ4 G3RAJ4 ALOX5 PTHR11771:SF5 LIPOXYGENASE POLYUNSATURATED FATTY ACID 5-LIPOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;arachidonate metabolic process#GO:0019369;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;icosanoid metabolic process#GO:0006690 organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000010519.3|UniProtKB=A0A2I2YQI1 A0A2I2YQI1 BRMS1 PTHR21964:SF15 BREAST CANCER METASTASIS-SUPPRESSOR 1 BREAST CANCER METASTASIS-SUPPRESSOR 1 protein binding#GO:0005515;histone deacetylase binding#GO:0042826;enzyme binding#GO:0019899;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000005971.3|UniProtKB=A0A2I2Y3D3 A0A2I2Y3D3 LOC101144405 PTHR10218:SF329 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 cell communication#GO:0007154;regulation of biological quality#GO:0065008;response to nitrogen compound#GO:1901698;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to oxygen-containing compound#GO:1901700;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;action potential#GO:0001508;regulation of membrane potential#GO:0042391;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell surface receptor signaling pathway#GO:0007166;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701 extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797 G-protein#PC00020;heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Endothelin signaling pathway#P00019>Gq#P00586;Gonadotropin-releasing hormone receptor pathway#P06664>gnaq/11#P06841;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Wnt signaling pathway#P00057>Galpha#P01451;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gqalpha#P05927;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057 GORGO|Ensembl=ENSGGOG00000006330.3|UniProtKB=G3QU06 G3QU06 PPP4R1 PTHR10648:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 GORGO|Ensembl=ENSGGOG00000003773.3|UniProtKB=G3S413 G3S413 CERKL PTHR12358:SF26 SPHINGOSINE KINASE CERAMIDE KINASE-LIKE PROTEIN lipid kinase activity#GO:0001727;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000026532.2|UniProtKB=G3S9H0 G3S9H0 EHMT2 PTHR46307:SF1 G9A, ISOFORM B HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000005990.3|UniProtKB=G3QT50 G3QT50 GPR137B PTHR15146:SF0 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137B regulation of tissue remodeling#GO:0034103;positive regulation of TOR signaling#GO:0032008;regulation of hemopoiesis#GO:1903706;negative regulation of multicellular organismal process#GO:0051241;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;positive regulation of TORC1 signaling#GO:1904263;regulation of bone remodeling#GO:0046850;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of bone resorption#GO:0045124;regulation of intracellular signal transduction#GO:1902531;regulation of myeloid cell differentiation#GO:0045637;positive regulation of signaling#GO:0023056;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239 cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000024543.2|UniProtKB=G3RNB1 G3RNB1 ZSCAN23 PTHR23226:SF76 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 23 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008749.3|UniProtKB=G3S6F8 G3S6F8 MED1 PTHR12881:SF16 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;transcription regulator activity#GO:0140110 response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000006385.3|UniProtKB=G3RX14 G3RX14 SPNS2 PTHR23505:SF4 SPINSTER SPHINGOSINE-1-PHOSPHATE TRANSPORTER SPNS2 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 lipid localization#GO:0010876;G protein-coupled receptor signaling pathway#GO:0007186;localization#GO:0051179;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;transport#GO:0006810;establishment of localization#GO:0051234;signal transduction#GO:0007165;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024342.2|UniProtKB=A0A2I2ZU87 A0A2I2ZU87 ACADM PTHR48083:SF41 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000028585.2|UniProtKB=G3S6T7 G3S6T7 LOC101136829 PTHR10956:SF41 60S RIBOSOMAL PROTEIN L31 LARGE RIBOSOMAL SUBUNIT PROTEIN EL31 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Gene=TAS2R41|UniProtKB=Q645Y3 Q645Y3 TAS2R41 PTHR11394:SF73 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 41 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000017105.3|UniProtKB=G3RLN7 G3RLN7 FAM177B PTHR31206:SF9 LP10445P PROTEIN FAM177B GORGO|Ensembl=ENSGGOG00000011030.3|UniProtKB=G3R621 G3R621 CAGE1 PTHR36864:SF1 CANCER-ASSOCIATED GENE 1 PROTEIN CANCER-ASSOCIATED GENE 1 PROTEIN GORGO|Ensembl=ENSGGOG00000000271.3|UniProtKB=G3QDF1 G3QDF1 DDX10 PTHR24031:SF775 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX10-RELATED gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000041408.1|UniProtKB=G3RY71 G3RY71 PTHR23267:SF413 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 1-44-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000007739.3|UniProtKB=G3QXM2 G3QXM2 GGH PTHR11315:SF20 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE GAMMA-GLUTAMYL HYDROLASE cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000008869.3|UniProtKB=G3R0I7 G3R0I7 MMP1 PTHR10201:SF151 MATRIX METALLOPROTEINASE INTERSTITIAL COLLAGENASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056 metalloprotease#PC00153 Plasminogen activating cascade#P00050>MMP-1#P01252;Plasminogen activating cascade#P00050>pro-MMP-1#P01263;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000027413.2|UniProtKB=G3S4T3 G3S4T3 IFNK PTHR11691:SF6 TYPE I INTERFERON INTERFERON KAPPA protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;protein binding#GO:0005515;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312;immune system process#GO:0002376;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;T cell activation#GO:0042110;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;cell surface receptor signaling pathway#GO:0007166;natural killer cell activation#GO:0030101;humoral immune response#GO:0006959;B cell activation#GO:0042113;cellular process#GO:0009987;defense response to symbiont#GO:0140546;lymphocyte activation involved in immune response#GO:0002285;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;T cell activation involved in immune response#GO:0002286;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127;cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000025980.2|UniProtKB=A0A2I2ZYF3 A0A2I2ZYF3 NDUFAF1 PTHR13194:SF23 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000006513.3|UniProtKB=A0A2I2ZJ98 A0A2I2ZJ98 ACSF2 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 metabolite interconversion enzyme#PC00262;ligase#PC00142 GORGO|Ensembl=ENSGGOG00000009139.3|UniProtKB=G3S544 G3S544 DPF3 PTHR23057:SF4 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 ZINC FINGER PROTEIN DPF3 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000043613.1|UniProtKB=G3R9J4 G3R9J4 LOC101128089 PTHR23260:SF5 KERATIN ASSOCIATED PROTEIN 3-3-RELATED KERATIN-ASSOCIATED PROTEIN 3-2 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000011019.3|UniProtKB=G3R603 G3R603 DUSP29 PTHR45682:SF6 AGAP008228-PA DUAL SPECIFICITY PHOSPHATASE 29 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000026707.2|UniProtKB=G3RW25 G3RW25 RPSA PTHR11489:SF17 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2-RELATED structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025992.2|UniProtKB=G3S6K7 G3S6K7 LOC101142104 PTHR21184:SF4 MENORIN (DENDRITIC BRANCHING PROTEIN) PROTEIN FAM151A cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000026973.2|UniProtKB=G3RZX1 G3RZX1 LOC101143628 PTHR31866:SF3 GENE 4779-RELATED SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000010135.3|UniProtKB=A0A2I2YG60 A0A2I2YG60 ALDH16A1 PTHR11699:SF211 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1 aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000010795.3|UniProtKB=G3R5F1 G3R5F1 NOD2 PTHR24107:SF19 YNEIN REGULATORY COMPLEX SUBUNIT 5 NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000039762.1|UniProtKB=A0A2I2ZRN7 A0A2I2ZRN7 PTHR11278:SF5 40S RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN ES7 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;small-subunit processome#GO:0032040;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010280.3|UniProtKB=G3R444 G3R444 GSTM3 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000002169.3|UniProtKB=G3QID3 G3QID3 BBS7 PTHR16074:SF4 BARDET-BIEDL SYNDROME 7 PROTEIN BBSOME COMPLEX MEMBER BBS7 organelle assembly#GO:0070925;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;BBSome#GO:0034464;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815 GORGO|Ensembl=ENSGGOG00000009904.3|UniProtKB=G3R355 G3R355 HOXB1 PTHR45946:SF5 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-B1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004690.3|UniProtKB=G3QPU1 G3QPU1 ARC PTHR15962:SF0 ACTIVITY-REGULATED CYTOSKELETON-ASSOCIATED PROTEIN ACTIVITY-REGULATED CYTOSKELETON-ASSOCIATED PROTEIN regulation of biological quality#GO:0065008;regulation of neuronal synaptic plasticity#GO:0048168;regulation of signaling#GO:0023051;regulation of synaptic plasticity#GO:0048167;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection cytoplasm#GO:0120111;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013413.3|UniProtKB=G3RC60 G3RC60 SHC1 PTHR10337:SF2 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 1 molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;enzyme binding#GO:0019899 cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to insulin stimulus#GO:0032869;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to nitrogen compound#GO:1901699;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to nitrogen compound#GO:1901698;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Shc#P00183;CCKR signaling map#P06959>SHC1 @EGFR#P07083;FGF signaling pathway#P00021>Shc#P00639;CCKR signaling map#P06959>p52 SHC1#P07151;Integrin signalling pathway#P00034>Shc#P00949;Ras Pathway#P04393>Shc#P04579;PDGF signaling pathway#P00047>Shc#P01175;CCKR signaling map#P06959>p66 SHC1#P07168;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Shc#P00865;Interleukin signaling pathway#P00036>Shc#P00997;CCKR signaling map#P06959>SHC1#P07138;CCKR signaling map#P06959>p46 SHC1#P07098;EGF receptor signaling pathway#P00018>Shc#P00554 GORGO|Ensembl=ENSGGOG00000005444.3|UniProtKB=G3QRR9 G3QRR9 SLC39A11 PTHR11040:SF211 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP11 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000009606.3|UniProtKB=G3R2D5 G3R2D5 LOC101153072 PTHR43313:SF4 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 6 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745 small molecule metabolic process#GO:0044281;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;cellular process#GO:0009987;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 GORGO|Ensembl=ENSGGOG00000015337.3|UniProtKB=G3RH47 G3RH47 HIGD2B PTHR12297:SF8 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 2B cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014334.3|UniProtKB=G3REJ1 G3REJ1 LRRC14 PTHR14224:SF114 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14 molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899 modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;protein metabolic process#GO:0019538;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stress#GO:0080134;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of innate immune response#GO:0045088;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;regulation of response to external stimulus#GO:0032101;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul2-RING ubiquitin ligase complex#GO:0031462;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001782.3|UniProtKB=G3QHD0 G3QHD0 TMEM210 PTHR39234:SF1 TRANSMEMBRANE PROTEIN 210 TRANSMEMBRANE PROTEIN 210 intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000024969.2|UniProtKB=A0A2I2ZDP0 A0A2I2ZDP0 PTHR19877:SF16 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;SMN complex#GO:0032797;Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000036209.1|UniProtKB=A0A2I2ZUZ9 A0A2I2ZUZ9 VPS72 PTHR13275:SF4 YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;intracellular organelle lumen#GO:0070013;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000026930.2|UniProtKB=G3SBR9 G3SBR9 LOC101139163 PTHR14614:SF139 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN FAM86 N-TERMINAL DOMAIN-CONTAINING PROTEIN transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;lysine N-methyltransferase activity#GO:0016278 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009332.3|UniProtKB=G3R1N4 G3R1N4 OXLD1 PTHR21193:SF3 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000004838.3|UniProtKB=A0A2I2ZKJ1 A0A2I2ZKJ1 TSPAN32 PTHR19282:SF51 TETRASPANIN TETRASPANIN-32 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014761.3|UniProtKB=G3RFN2 G3RFN2 PSMD12 PTHR10855:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;proteasome complex#GO:0000502 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 GORGO|Ensembl=ENSGGOG00000017128.3|UniProtKB=G3RLQ7 G3RLQ7 RAPGEF5 PTHR23113:SF26 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 5 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000014969.3|UniProtKB=G3RG69 G3RG69 SYT12 PTHR10024:SF252 SYNAPTOTAGMIN SYNAPTOTAGMIN-12 SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299;protein binding#GO:0005515 biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 GORGO|Ensembl=ENSGGOG00000002357.3|UniProtKB=G3QIV0 G3QIV0 GLB1L2 PTHR23421:SF53 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE-1-LIKE PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 galactosidase#PC00104;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000024965.2|UniProtKB=G3SI66 G3SI66 OTUD7B PTHR13367:SF8 UBIQUITIN THIOESTERASE OTU DOMAIN-CONTAINING PROTEIN 7B polyubiquitin modification-dependent protein binding#GO:0031593;catalytic activity#GO:0003824;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;binding#GO:0005488;modification-dependent protein binding#GO:0140030;hydrolase activity#GO:0016787;protein binding#GO:0005515 negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;post-translational protein modification#GO:0043687;regulation of canonical NF-kappaB signal transduction#GO:0043122;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000040611.1|UniProtKB=A0A2I2Z4Z4 A0A2I2Z4Z4 PTHR21304:SF7 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000007292.3|UniProtKB=G3QWH8 G3QWH8 COPRS PTHR36461:SF1 COORDINATOR OF PRMT5 AND DIFFERENTIATION STIMULATOR COORDINATOR OF PRMT5 AND DIFFERENTIATION STIMULATOR protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000007635.3|UniProtKB=G3QXD0 G3QXD0 AIFM1 PTHR43557:SF4 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166 intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;programmed cell death#GO:0012501;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;mitochondrial transport#GO:0006839;mitochondrial protein import pathway#GO:7770058 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176 Apoptosis signaling pathway#P00006>AIF#P00286 GORGO|Ensembl=ENSGGOG00000003911.3|UniProtKB=G3RXV7 G3RXV7 ADPGK PTHR21208:SF0 ADP-DEPENDENT GLUCOKINASE ADP-DEPENDENT GLUCOKINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000003190.3|UniProtKB=G3QL01 G3QL01 WDR44 PTHR14221:SF72 WD REPEAT DOMAIN 44 WD REPEAT-CONTAINING PROTEIN 44 organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;regulation of localization#GO:0032879;regulation of transport#GO:0051049;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000005442.3|UniProtKB=G3S7N2 G3S7N2 EFCAB3 PTHR22656:SF2 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 13 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000013406.3|UniProtKB=G3RZV8 G3RZV8 LOC101137477 PTHR26453:SF50 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2A12 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Gene=TAS2R13|UniProtKB=Q645Z5 Q645Z5 TAS2R13 PTHR11394:SF28 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 13 transmembrane signaling receptor activity#GO:0004888;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000039961.1|UniProtKB=A0A2I2YEJ5 A0A2I2YEJ5 LOC109029095 PTHR26454:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C6 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005774.3|UniProtKB=G3QSL6 G3QSL6 SRSF11 PTHR32343:SF6 SERINE/ARGININE-RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 11 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000011376.3|UniProtKB=G3R6X0 G3R6X0 RGS4 PTHR10845:SF184 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 4 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589 negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944 GTPase-activating protein#PC00257 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 GORGO|Ensembl=ENSGGOG00000016226.3|UniProtKB=G3RJE1 G3RJE1 LOC101150373 PTHR26453:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13D1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012309.3|UniProtKB=G3R9C9 G3R9C9 PIMREG PTHR35819:SF1 PICALM INTERACTING MITOTIC REGULATOR PIMREG PROTEIN PIMREG GORGO|Ensembl=ENSGGOG00000004362.3|UniProtKB=G3QNZ7 G3QNZ7 PTGDS PTHR11430:SF86 LIPOCALIN PROSTAGLANDIN-H2 D-ISOMERASE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000040018.1|UniProtKB=A0A2I2ZFF5 A0A2I2ZFF5 NCBP2AS2 PTHR41161:SF1 PROTEIN NCBP2AS2 PROTEIN NCBP2AS2 GORGO|Ensembl=ENSGGOG00000013894.3|UniProtKB=G3SE44 G3SE44 BEX5 PTHR19430:SF0 PROTEIN BEX1-RELATED PROTEIN BEX5 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000004756.3|UniProtKB=G3QQ06 G3QQ06 WDR33 PTHR22836:SF0 WD40 REPEAT PROTEIN PRE-MRNA 3' END PROCESSING PROTEIN WDR33 mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000041674.1|UniProtKB=G3RR53 G3RR53 PTHR19256:SF54 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 8 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000025213.2|UniProtKB=A0A2I2Y914 A0A2I2Y914 PTHR11071:SF532 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000022267.2|UniProtKB=A0A2I2ZTJ9 A0A2I2ZTJ9 CSTF2 PTHR45735:SF6 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000023033.2|UniProtKB=G3S547 G3S547 TOMM40 PTHR10802:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 HOMOLOG transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014705.3|UniProtKB=A0A2I2ZQ67 A0A2I2ZQ67 C9H11orf54 PTHR13204:SF1 PTD012 PROTEIN BETA-KETO L-GULONATE DECARBOXYLASE ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000027712.2|UniProtKB=G3RWI9 G3RWI9 CD80 PTHR25466:SF4 T-LYMPHOCYTE ACTIVATION ANTIGEN T-LYMPHOCYTE ACTIVATION ANTIGEN CD80 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>B7#P01337 GORGO|Ensembl=ENSGGOG00000037967.1|UniProtKB=A0A2I2ZRX6 A0A2I2ZRX6 ABHD13 PTHR12277:SF207 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD13 palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000012916.3|UniProtKB=G3RAX2 G3RAX2 PHYKPL PTHR45688:SF6 FAMILY NOT NAMED 5-PHOSPHOHYDROXY-L-LYSINE PHOSPHO-LYASE GORGO|Ensembl=ENSGGOG00000008712.3|UniProtKB=G3R048 G3R048 MSH3 PTHR11361:SF158 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH3 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676 multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;somatic cell DNA recombination#GO:0016444;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;developmental process#GO:0032502;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;system development#GO:0048731;mitotic recombination#GO:0006312;gene expression#GO:0010467;response to stress#GO:0006950;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;multicellular organism development#GO:0007275;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;mismatch repair#GO:0006298;immune system development#GO:0002520;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;cellular response to stress#GO:0033554 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000000573.3|UniProtKB=G3QE74 G3QE74 SBK1 PTHR24359:SF0 SERINE/THREONINE-PROTEIN KINASE SBK1 SERINE_THREONINE-PROTEIN KINASE SBK1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000013881.3|UniProtKB=G3RDD8 G3RDD8 CMTM4 PTHR22776:SF29 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4 immune system process#GO:0002376;immune response#GO:0006955;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007673.3|UniProtKB=G3QXG1 G3QXG1 ZNF780B PTHR23226:SF191 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 780B nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022358.2|UniProtKB=G3RVB6 G3RVB6 PDZD2 PTHR11324:SF16 IL16-RELATED PDZ DOMAIN-CONTAINING PROTEIN 2 cytokine#PC00083;interleukin superfamily#PC00128 GORGO|Ensembl=ENSGGOG00000004806.3|UniProtKB=G3SK14 G3SK14 PTHR20884:SF8 GDP-D-GLUCOSE PHOSPHORYLASE 1 GDP-D-GLUCOSE PHOSPHORYLASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000026359.2|UniProtKB=G3RYH1 G3RYH1 PPHLN1 PTHR15836:SF4 PERIPHILIN 1 PERIPHILIN-1 negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;macromolecule localization#GO:0033036;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;localization#GO:0051179;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 GORGO|Ensembl=ENSGGOG00000025840.2|UniProtKB=G3RNV9 G3RNV9 KRT23 PTHR23239:SF44 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 23 structural molecule activity#GO:0005198 cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;developmental process#GO:0032502;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000014240.3|UniProtKB=G3REA6 G3REA6 TMEM79 PTHR31004:SF1 TRANSMEMBRANE PROTEIN 79 TRANSMEMBRANE PROTEIN 79 exocytosis#GO:0006887;secretion by cell#GO:0032940;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;regulated exocytosis#GO:0045055;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588 GORGO|Ensembl=ENSGGOG00000006621.3|UniProtKB=G3S106 G3S106 PLK4 PTHR24345:SF89 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK4 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000010023.3|UniProtKB=G3RV53 G3RV53 C1H1orf116 PTHR21555:SF0 SPECIFICALLY ANDROGEN-REGULATED GENE PROTEIN SPECIFICALLY ANDROGEN-REGULATED GENE PROTEIN response to steroid hormone#GO:0048545;cellular response to chemical stimulus#GO:0070887;intracellular signal transduction#GO:0035556;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;intracellular receptor signaling pathway#GO:0030522;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to steroid hormone stimulus#GO:0071383;cellular process#GO:0009987;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;nuclear receptor-mediated signaling pathway#GO:0141193;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000004016.3|UniProtKB=G3QN34 G3QN34 KPNA6 PTHR23316:SF8 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-7 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002195.3|UniProtKB=A0A2I2YTJ8 A0A2I2YTJ8 HOMEZ PTHR15467:SF7 ZINC-FINGERS AND HOMEOBOXES RELATED HOMEOBOX AND LEUCINE ZIPPER PROTEIN HOMEZ DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000025222.2|UniProtKB=G3RVT0 G3RVT0 PNRC1 PTHR15405:SF4 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000041865.1|UniProtKB=A0A2I2YP66 A0A2I2YP66 SPMIP11 PTHR35263:SF1 TESTIS-EXPRESSED PROTEIN 49 SPERM MICROTUBULE INNER PROTEIN 11 microtubule cytoskeleton#GO:0015630;A axonemal microtubule#GO:0097649;supramolecular complex#GO:0099080;axonemal doublet microtubule#GO:0097545;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule#GO:0005874;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000012151.3|UniProtKB=G3R8Y0 G3R8Y0 AQP9 PTHR43829:SF6 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-9 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;carbohydrate transmembrane transporter activity#GO:0015144;channel activity#GO:0015267 carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987;organic hydroxy compound transport#GO:0015850;fluid transport#GO:0042044;water transport#GO:0006833;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040966.1|UniProtKB=A0A2I2YUR8 A0A2I2YUR8 HS2ST1 PTHR12129:SF17 HEPARAN SULFATE 2-O-SULFOTRANSFERASE HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000011970.3|UniProtKB=G3R8H4 G3R8H4 RORB PTHR45805:SF6 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-BETA sequence-specific double-stranded DNA binding#GO:1990837;G protein-coupled receptor activity#GO:0004930;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transmembrane signaling receptor activity#GO:0004888;transcription regulatory region nucleic acid binding#GO:0001067 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000012418.3|UniProtKB=G3R9N5 G3R9N5 PRPS1 PTHR10210:SF128 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000038247.1|UniProtKB=A0A2I2YGI8 A0A2I2YGI8 PTHR23267:SF536 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-30-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000028476.2|UniProtKB=G3RU45 G3RU45 DGAT1 PTHR10408:SF7 STEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid metabolic process#GO:0006638;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 acyltransferase#PC00042;transferase#PC00220 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 GORGO|Ensembl=ENSGGOG00000008740.3|UniProtKB=G3R064 G3R064 TMEM125 PTHR31416:SF1 TRANSMEMBRANE PROTEIN 125 TRANSMEMBRANE PROTEIN 125 GORGO|Ensembl=ENSGGOG00000007540.3|UniProtKB=G3QX51 G3QX51 LBP PTHR10504:SF66 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED LIPOPOLYSACCHARIDE-BINDING PROTEIN lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 response to lipopolysaccharide#GO:0032496;positive regulation of leukocyte activation#GO:0002696;leukocyte activation involved in immune response#GO:0002366;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;response to lipid#GO:0033993;defense response to other organism#GO:0098542;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;myeloid leukocyte activation#GO:0002274;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;regulation of macrophage activation#GO:0043030;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cell activation involved in immune response#GO:0002263;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;defense response to Gram-positive bacterium#GO:0050830;response to molecule of bacterial origin#GO:0002237;macrophage activation#GO:0042116;cellular response to molecule of bacterial origin#GO:0071219;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;multicellular organismal process#GO:0032501;response to other organism#GO:0051707;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;acute inflammatory response#GO:0002526;response to bacterium#GO:0009617;lipopolysaccharide-mediated signaling pathway#GO:0031663;cell activation#GO:0001775;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000005484.3|UniProtKB=G3QRW0 G3QRW0 BICC1 PTHR10627:SF78 SCP160 PROTEIN BICAUDAL C HOMOLOG 1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000040268.1|UniProtKB=G3QZ75 G3QZ75 LOC101152824 PTHR24103:SF613 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIM49 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;biological regulation#GO:0065007;response to other organism#GO:0051707;defense response to other organism#GO:0098542;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000006019.3|UniProtKB=A0A2I2YHF8 A0A2I2YHF8 LOC101144524 PTHR28627:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000003259.3|UniProtKB=G3QL59 G3QL59 WNT6 PTHR12027:SF72 WNT RELATED PROTEIN WNT-6 molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell fate commitment#GO:0045165;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 GORGO|Ensembl=ENSGGOG00000044115.1|UniProtKB=A0A2I2Y5V8 A0A2I2Y5V8 PXMP4 PTHR15460:SF3 PEROXISOMAL MEMBRANE PROTEIN 4 PEROXISOMAL MEMBRANE PROTEIN 4 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000014897.3|UniProtKB=G3RG04 G3RG04 IMMP1L PTHR12383:SF33 PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585 mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;peptidase complex#GO:1905368;cytoplasm#GO:0005737;endopeptidase complex#GO:1905369;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000012038.3|UniProtKB=A0A2I2ZYA1 A0A2I2ZYA1 UBASH3A PTHR16469:SF7 UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING PROTEIN A negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040178.1|UniProtKB=A0A2I2ZTI2 A0A2I2ZTI2 RIF1 PTHR22928:SF4 TELOMERE-ASSOCIATED PROTEIN RIF1 TELOMERE-ASSOCIATED PROTEIN RIF1 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000005040.3|UniProtKB=G3QQR5 G3QQR5 GSDMA PTHR16399:SF18 GASDERMIN GASDERMIN-A transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010301.3|UniProtKB=G3R462 G3R462 LOC101134521 PTHR23424:SF32 SERUM AMYLOID A SERUM AMYLOID A-2 PROTEIN transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000001728.3|UniProtKB=G3QH81 G3QH81 REV1 PTHR45990:SF1 DNA REPAIR PROTEIN REV1 TRANSLESION SYNTHESIS PROTEIN REV1 DNA-directed DNA polymerase activity#GO:0003887;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;translesion synthesis#GO:0019985;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592 nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000011523.3|UniProtKB=G3S0A8 G3S0A8 SMPDL3A PTHR10340:SF24 SPHINGOMYELIN PHOSPHODIESTERASE CYCLIC GMP-AMP PHOSPHODIESTERASE SMPDL3A hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000005497.3|UniProtKB=G3QRX2 G3QRX2 SLC12A8 PTHR11827:SF6 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 8 monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000013755.3|UniProtKB=G3RD19 G3RD19 PDHA2 PTHR11516:SF27 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA, TESTIS-SPECIFIC FORM, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293 transferase complex#GO:1990234;membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092;oxidoreductase#PC00176 Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133;TCA cycle#P00051>Pyruvate Dehydrogenase#P01266 GORGO|Ensembl=ENSGGOG00000011721.3|UniProtKB=A0A2I2YPH3 A0A2I2YPH3 IGFBP2 PTHR11551:SF5 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 2 binding#GO:0005488;growth factor binding#GO:0019838;protein binding#GO:0005515 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000015589.3|UniProtKB=G3RHT1 G3RHT1 PTK2B PTHR24418:SF94 TYROSINE-PROTEIN KINASE PROTEIN-TYROSINE KINASE 2-BETA kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell adhesion#GO:0030155;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of cell migration#GO:0030335;ERBB signaling pathway#GO:0038127;positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell motility#GO:2000147;regulation of cell motility#GO:2000145;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 anchoring junction#GO:0070161;cell junction#GO:0030054;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 Integrin signalling pathway#P00034>FAK#P00932;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PYK2#P00852;Gonadotropin-releasing hormone receptor pathway#P06664>Pyk2#P06730;CCKR signaling map#P06959>FAK2#P07218 GORGO|Ensembl=ENSGGOG00000016310.3|UniProtKB=A0A2I2YCP9 A0A2I2YCP9 HIP1 PTHR10407:SF14 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN-INTERACTING PROTEIN 1 phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;cytoskeletal adaptor activity#GO:0008093;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein-membrane adaptor activity#GO:0043495;lipid binding#GO:0008289;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin binding#GO:0003779;actin filament binding#GO:0051015 protein-containing complex organization#GO:0043933;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;endocytosis#GO:0006897;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;actin filament organization#GO:0007015;establishment of localization#GO:0051234;regulation of response to stimulus#GO:0048583;transport#GO:0006810;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;supramolecular fiber organization#GO:0097435;localization#GO:0051179;actin filament-based process#GO:0030029;regulation of cell communication#GO:0010646;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of ERBB signaling pathway#GO:1901184;positive regulation of signal transduction#GO:0009967 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cell cortex#GO:0005938;membraneless organelle#GO:0043228;cell junction#GO:0030054;clathrin-coated vesicle#GO:0030136;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;presynapse#GO:0098793 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Huntington disease#P00029>Hip-1#P00765 GORGO|Ensembl=ENSGGOG00000034876.2|UniProtKB=G3SKL2 G3SKL2 FRK PTHR24418:SF468 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FRK transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672 enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Blk#P00390;Integrin signalling pathway#P00034>Src#P00940;Parkinson disease#P00049>Src kinase#P01230;Parkinson disease#P00049>Fyn kinase#P01235;Axon guidance mediated by semaphorins#P00007>Fyn#P00335;Cadherin signaling pathway#P00012>Fyn#P00464 GORGO|Ensembl=ENSGGOG00000002909.3|UniProtKB=A0A2I2Y2B1 A0A2I2Y2B1 LOC101137195 PTHR22600:SF39 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE SUBUNIT ALPHA hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycoprotein metabolic process#GO:0009100;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;ceramide metabolic process#GO:0006672;sphingolipid catabolic process#GO:0030149;glycosaminoglycan metabolic process#GO:0030203;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative catabolic process#GO:1901136;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664 membrane#GO:0016020;cell periphery#GO:0071944;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;extracellular region#GO:0005576;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000016539.3|UniProtKB=G3RK81 G3RK81 CTH PTHR11808:SF15 TRANS-SULFURATION ENZYME FAMILY MEMBER CYSTATHIONINE GAMMA-LYASE lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;homocysteine metabolic process#GO:0050667;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lyase#PC00144 Methionine biosynthesis#P02753>O-Succinyl homoserine lyase#P03026 GORGO|Ensembl=ENSGGOG00000011239.3|UniProtKB=G3R6J8 G3R6J8 LOC101149238 PTHR14179:SF8 SMR1-RELATED OPIORPHIN PREPROPEPTIDE enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of system process#GO:0044057;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000013242.3|UniProtKB=G3RBQ3 G3RBQ3 TIMP3 PTHR11844:SF22 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 3 molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 regulation of protein catabolic process#GO:0042176;response to peptide#GO:1901652;negative regulation of catabolic process#GO:0009895;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of proteolysis#GO:0030162;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;response to chemical#GO:0042221;negative regulation of protein catabolic process#GO:0042177;response to cytokine#GO:0034097 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000027732.2|UniProtKB=G3S7N0 G3S7N0 PTHR24072:SF144 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOV heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 supramolecular fiber organization#GO:0097435;localization#GO:0051179;cell communication#GO:0007154;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;signaling#GO:0023052;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;actin filament organization#GO:0007015;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000006362.3|UniProtKB=G3QU44 G3QU44 FAT2 PTHR24025:SF16 DESMOGLEIN FAMILY MEMBER FAT ATYPICAL CADHERIN 2 calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000024043.2|UniProtKB=G3RNS6 G3RNS6 DEPDC7 PTHR16206:SF9 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009767.3|UniProtKB=G3RZ06 G3RZ06 MARCHF5 PTHR46283:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of mitochondrial fission#GO:0090140;regulation of developmental process#GO:0050793;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005635.3|UniProtKB=G3QS92 G3QS92 SRCIN1 PTHR22741:SF5 P140CAP/SNIP-RELATED SRC KINASE SIGNALING INHIBITOR 1 regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;regulation of neuron projection development#GO:0010975;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of synapse organization#GO:0050807;regulation of dendritic spine morphogenesis#GO:0061001;regulation of cell projection organization#GO:0031344;regulation of biological quality#GO:0065008;regulation of anatomical structure morphogenesis#GO:0022603;regulation of synapse structure or activity#GO:0050803;regulation of plasma membrane bounded cell projection organization#GO:0120035 actin cytoskeleton#GO:0015629;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;intracellular anatomical structure#GO:0005622;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000022560.2|UniProtKB=A0A2I2Y3U8 A0A2I2Y3U8 LOC101148636 PTHR22175:SF2 SMALL ACIDIC PROTEIN-RELATED SMALL ACIDIC PROTEIN-LIKE DOMAIN-CONTAINING PROTEIN nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000023784.2|UniProtKB=G3RTX3 G3RTX3 SPOCK2 PTHR13866:SF18 SPARC OSTEONECTIN TESTICAN-2 cation binding#GO:0043169;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;peptidase regulator activity#GO:0061134;calcium ion binding#GO:0005509;ion binding#GO:0043167;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;binding#GO:0005488;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of biological process#GO:0050789 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000012120.3|UniProtKB=G3R8W1 G3R8W1 MACROD1 PTHR11106:SF93 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED ADP-RIBOSE GLYCOHYDROLASE MACROD1 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleoside metabolic process#GO:0042278;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;nucleoside metabolic process#GO:0009116;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;carbohydrate derivative metabolic process#GO:1901135 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000002879.3|UniProtKB=A0A2I2Y6B6 A0A2I2Y6B6 PTHR23226:SF184 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 29 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001688.3|UniProtKB=A0A2I2Y8U0 A0A2I2Y8U0 DLG1 PTHR23119:SF5 DISCS LARGE DISKS LARGE HOMOLOG 1 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;signaling receptor binding#GO:0005102;binding#GO:0005488;kinase binding#GO:0019900 multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;nervous system development#GO:0007399;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;receptor clustering#GO:0043113;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;developmental process#GO:0032502;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;protein localization to cell junction#GO:1902414;trans-synaptic signaling#GO:0099537;establishment or maintenance of apical/basal cell polarity#GO:0035088;localization within membrane#GO:0051668;establishment or maintenance of bipolar cell polarity#GO:0061245;localization#GO:0051179;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916 synaptic membrane#GO:0097060;cell junction#GO:0030054;neuromuscular junction#GO:0031594;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;neuron projection#GO:0043005;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;basal part of cell#GO:0045178;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000024986.2|UniProtKB=G3S7F9 G3S7F9 LOC109028586 PTHR15438:SF14 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER A1-RELATED GORGO|Ensembl=ENSGGOG00000009732.3|UniProtKB=A0A2I2ZKV0 A0A2I2ZKV0 LOC101136971 PTHR14928:SF13 MICRO-RNA BINDING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036621.1|UniProtKB=A0A2I2ZLT4 A0A2I2ZLT4 ZBTB6 PTHR24399:SF36 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000006732.3|UniProtKB=G3QV24 G3QV24 OTUB2 PTHR12931:SF3 UBIQUITIN THIOLESTERASE PROTEIN OTUB UBIQUITIN THIOESTERASE OTUB2 ubiquitin binding#GO:0043130;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000014712.3|UniProtKB=A0A2I2Y6E5 A0A2I2Y6E5 CCDC183 PTHR47115:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 183 COILED-COIL DOMAIN-CONTAINING PROTEIN 183 GORGO|Ensembl=ENSGGOG00000022295.2|UniProtKB=G3SAL4 G3SAL4 PTHR22761:SF57 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 5 endosomal transport#GO:0016197;nuclear envelope organization#GO:0006998;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;localization#GO:0051179;cellular localization#GO:0051641;late endosome to vacuole transport#GO:0045324;membrane assembly#GO:0071709;cellular component organization#GO:0016043 vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000009794.3|UniProtKB=G3R2W2 G3R2W2 CENPC PTHR16684:SF12 CENTROMERE PROTEIN C CENTROMERE PROTEIN C nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690 mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;mitotic cell cycle#GO:0000278;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;nuclear division#GO:0000280;organelle localization#GO:0051640;localization#GO:0051179;kinetochore organization#GO:0051383;organelle fission#GO:0048285;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;attachment of spindle microtubules to kinetochore#GO:0008608;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 centromere DNA-binding protein#PC00071 GORGO|Ensembl=ENSGGOG00000025649.2|UniProtKB=A0A2I2ZS61 A0A2I2ZS61 RAP1B PTHR24070:SF393 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1B-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 negative regulation of cellular process#GO:0048523;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of neurotransmitter transport#GO:0051588;regulation of secretion by cell#GO:1903530;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;response to stimulus#GO:0050896;regulation of neurotransmitter secretion#GO:0046928 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#G06881;Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#P06803;Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#G06668;Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 GORGO|Ensembl=ENSGGOG00000010721.3|UniProtKB=G3R587 G3R587 SLCO1A2 PTHR11388:SF16 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1A2 bile acid transmembrane transporter activity#GO:0015125;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006967.3|UniProtKB=G3QVP5 G3QVP5 F2 PTHR24254:SF10 PROTHROMBIN PROTHROMBIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;multicellular organismal process#GO:0032501;regulation of coagulation#GO:0050818;positive regulation of response to stimulus#GO:0048584;regulation of hemostasis#GO:1900046;cellular process#GO:0009987;coagulation#GO:0050817;positive regulation of biological process#GO:0048518;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of response to wounding#GO:1903034;blood coagulation#GO:0007596;platelet activation#GO:0030168;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of wound healing#GO:0061041;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;regulation of blood coagulation#GO:0030193;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;hemostasis#GO:0007599;wound healing#GO:0042060;regulation of biological quality#GO:0065008;cell activation#GO:0001775;positive regulation of coagulation#GO:0050820 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 Blood coagulation#P00011>Prothrombin#P00416;Blood coagulation#P00011>Thrombin#P00414 GORGO|Ensembl=ENSGGOG00000000761.3|UniProtKB=G3RPT4 G3RPT4 LIPE PTHR23025:SF3 TRIACYLGLYCEROL LIPASE HORMONE-SENSITIVE LIPASE hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;triacylglycerol lipase activity#GO:0004806;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464;glycerolipid catabolic process#GO:0046503;acylglycerol metabolic process#GO:0006639;triglyceride catabolic process#GO:0019433;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid catabolic process#GO:0016042 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 Triacylglycerol metabolism#P02782>Triacylglycerol lipase#P03205 GORGO|Ensembl=ENSGGOG00000016587.3|UniProtKB=G3RKC2 G3RKC2 NLRC3 PTHR24107:SF28 YNEIN REGULATORY COMPLEX SUBUNIT 5 PROTEIN NLRC5 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000028503.2|UniProtKB=G3RW16 G3RW16 PRSS2 PTHR24264:SF57 TRYPSIN-RELATED TRYPSIN-2 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000004388.3|UniProtKB=G3S7S3 G3S7S3 ADAD1 PTHR10910:SF103 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 1 adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723;hydrolase activity#GO:0016787;double-stranded RNA binding#GO:0003725;tRNA-specific adenosine deaminase activity#GO:0008251;nucleic acid binding#GO:0003676;binding#GO:0005488;deaminase activity#GO:0019239;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 RNA biosynthetic process#GO:0032774;adenosine to inosine editing#GO:0006382;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base conversion or substitution editing#GO:0016553;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036313.1|UniProtKB=A0A2I2YL94 A0A2I2YL94 SPRR2D PTHR48553:SF3 SMALL PROLINE-RICH PROTEIN 2E SMALL PROLINE-RICH PROTEIN 2D GORGO|Ensembl=ENSGGOG00000022342.2|UniProtKB=G3SA05 G3SA05 PF4V1 PTHR12015:SF189 SMALL INDUCIBLE CYTOKINE A PLATELET FACTOR 4 VARIANT molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125 response to bacterium#GO:0009617;chemotaxis#GO:0006935;inflammatory response#GO:0006954;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;leukocyte migration#GO:0050900;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;immune response#GO:0006955;cell migration#GO:0016477;response to other organism#GO:0051707;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;response to molecule of bacterial origin#GO:0002237;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;biological process involved in interspecies interaction between organisms#GO:0044419;neutrophil chemotaxis#GO:0030593;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to lipopolysaccharide#GO:0032496;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;neutrophil migration#GO:1990266;taxis#GO:0042330;response to lipid#GO:0033993;defense response to other organism#GO:0098542;cellular response to lipid#GO:0071396;granulocyte migration#GO:0097530 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000002786.3|UniProtKB=G3QJY3 G3QJY3 LOC115931737 PTHR46186:SF5 CYSTATIN CYSTATIN-SN peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 vesicle#GO:0031982;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000014743.3|UniProtKB=G3RFL6 G3RFL6 SYT6 PTHR10024:SF45 SYNAPTOTAGMIN SYNAPTOTAGMIN-6 SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;protein binding#GO:0005515 trans-synaptic signaling#GO:0099537;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;transport#GO:0006810;regulation of transport#GO:0051049;regulation of localization#GO:0032879;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 GORGO|Ensembl=ENSGGOG00000039834.1|UniProtKB=A0A2I2ZIV2 A0A2I2ZIV2 LOC101124540 PTHR10956:SF48 60S RIBOSOMAL PROTEIN L31 LARGE RIBOSOMAL SUBUNIT PROTEIN EL31 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000011031.3|UniProtKB=G3R616 G3R616 PRX PTHR23348:SF42 PERIAXIN/AHNAK PERIAXIN animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;plasma membrane organization#GO:0007009;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;peripheral nervous system development#GO:0007422;cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;myelination#GO:0042552;gliogenesis#GO:0042063;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;endomembrane system organization#GO:0010256;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;membrane organization#GO:0061024;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000016086.3|UniProtKB=A0A2I2Y5U9 A0A2I2Y5U9 TRPM3 PTHR13800:SF7 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 3 calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025560.2|UniProtKB=A0A2I2ZU06 A0A2I2ZU06 PTHR13681:SF24 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED TUDOR DOMAIN-CONTAINING PROTEIN 3 chromatin-protein adaptor activity#GO:0140463;RNA binding#GO:0003723;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;siRNA-mediated heterochromatin formation#GO:0141194;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000002912.3|UniProtKB=G3QK95 G3QK95 PTHR10917:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 GORGO|Ensembl=ENSGGOG00000004577.3|UniProtKB=G3QPJ0 G3QPJ0 LOC101126229 PTHR24286:SF177 CYTOCHROME P450 26 CYTOCHROME P450 26B1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;regulation of hormone levels#GO:0010817;central nervous system development#GO:0007417;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;terpenoid metabolic process#GO:0006721;anatomical structure development#GO:0048856;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;system development#GO:0048731;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329;multicellular organismal process#GO:0032501;hormone metabolic process#GO:0042445;nervous system development#GO:0007399;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;developmental process#GO:0032502;retinoid metabolic process#GO:0001523;multicellular organism development#GO:0007275;diterpenoid metabolic process#GO:0016101 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000011965.3|UniProtKB=G3R8H1 G3R8H1 PRKCE PTHR24351:SF182 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Apoptosis signaling pathway#P00006>PKCs#P00318;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Endothelin signaling pathway#P00019>PKC#P00568;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Angiogenesis#P00005>PKC#P00219;VEGF signaling pathway#P00056>PKC#P01425 GORGO|Ensembl=ENSGGOG00000026528.2|UniProtKB=A0A2I2ZM20 A0A2I2ZM20 LOC101127528 PTHR12022:SF1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 7 electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex III#GO:0045275;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000041070.1|UniProtKB=A0A2I2YNV8 A0A2I2YNV8 PRSS56 PTHR24278:SF32 COAGULATION FACTOR SERINE PROTEASE 56 serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000036561.1|UniProtKB=A0A2I2YCV6 A0A2I2YCV6 PAQR7 PTHR20855:SF41 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR ALPHA DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;lipid binding#GO:0008289;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;steroid binding#GO:0005496;signaling receptor activity#GO:0038023 response to endogenous stimulus#GO:0009719;response to steroid hormone#GO:0048545;response to hormone#GO:0009725;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to lipid#GO:0033993 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000039577.1|UniProtKB=A0A2I2ZRB5 A0A2I2ZRB5 ZNF616 PTHR24399:SF91 ZINC FINGER AND BTB DOMAIN-CONTAINING NOVEL KRAB BOX AND ZINC FINGER, C2H2 TYPE DOMAIN CONTAINING PROTEIN-RELATED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000040470.1|UniProtKB=A0A2I2ZLD4 A0A2I2ZLD4 MFAP5 PTHR16485:SF6 MICROFIBRILLAR-ASSOCIATED PROTEIN 2 MICROFIBRILLAR-ASSOCIATED PROTEIN 5 anatomical structure morphogenesis#GO:0009653;visual system development#GO:0150063;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory system development#GO:0048880;embryo development#GO:0009790;multicellular organismal process#GO:0032501;developmental process#GO:0032502;sensory organ development#GO:0007423;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513 extracellular region#GO:0005576;supramolecular fiber#GO:0099512;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 GORGO|Ensembl=ENSGGOG00000013080.3|UniProtKB=G3RBC6 G3RBC6 FGFR1 PTHR24416:SF131 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 1 kinase activity#GO:0016301;transferase activity#GO:0016740;fibroblast growth factor binding#GO:0017134;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of developmental process#GO:0051094;response to fibroblast growth factor#GO:0071774;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636;Angiogenesis#P00005>FGFR-1#P00186 GORGO|Ensembl=ENSGGOG00000037614.1|UniProtKB=G3RXC1 G3RXC1 PTHR11861:SF1 MELANOCYTE PROTEIN PMEL 17-RELATED MELANOCYTE PROTEIN PMEL cellular pigmentation#GO:0033059;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;melanosome organization#GO:0032438;pigmentation#GO:0043473 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;melanosome#GO:0042470;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000023479.2|UniProtKB=A0A2I2YBT8 A0A2I2YBT8 PTHR16073:SF11 DCR DOMAIN-CONTAINING PROTEIN SAP DOMAIN-CONTAINING PROTEIN chromatin binding#GO:0003682;binding#GO:0005488 anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;system development#GO:0048731;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000041878.1|UniProtKB=A0A2I2Z5U7 A0A2I2Z5U7 PTHR11911:SF128 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED IMP DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000008871.3|UniProtKB=A0A2I2YCK6 A0A2I2YCK6 HAVCR1 PTHR47009:SF1 HEPATITIS A VIRUS CELLULAR RECEPTOR 1 HOMOLOG HEPATITIS A VIRUS CELLULAR RECEPTOR 1 virus receptor activity#GO:0001618;phospholipid binding#GO:0005543;protein binding#GO:0005515;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167 phagocytosis#GO:0006909;transport#GO:0006810;positive regulation of leukocyte activation#GO:0002696;membrane invagination#GO:0010324;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell activation#GO:0050867;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;membrane organization#GO:0061024;localization#GO:0051179;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;endocytosis#GO:0006897;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 GORGO|Ensembl=ENSGGOG00000011669.3|UniProtKB=G3R7N2 G3R7N2 ZNF625 PTHR24379:SF107 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 625 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000005764.3|UniProtKB=G3QSL0 G3QSL0 PER1 PTHR11269:SF8 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription factor binding#GO:0008134;double-stranded DNA binding#GO:0003690;protein binding#GO:0005515;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;rhythmic process#GO:0048511;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;photoperiodism#GO:0009648;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Gonadotropin-releasing hormone receptor pathway#P06664>mPer1#G06895;Gonadotropin-releasing hormone receptor pathway#P06664>mPer1#G06681;Circadian clock system#P00015>Per#P00504;Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>per#G01499 GORGO|Ensembl=ENSGGOG00000000351.3|UniProtKB=G3QDM2 G3QDM2 GRIK4 PTHR18966:SF171 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 4 transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;sodium ion transmembrane transporter activity#GO:0015081;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;carboxylic acid transmembrane transporter activity#GO:0046943;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;metal ion transmembrane transporter activity#GO:0046873;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916 membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;postsynaptic density membrane#GO:0098839 transmembrane signal receptor#PC00197 Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>KA4#P01001;Ionotropic glutamate receptor pathway#P00037>KA#P01026 GORGO|Ensembl=ENSGGOG00000038730.1|UniProtKB=A0A2I2Z9C6 A0A2I2Z9C6 ORM2 PTHR11967:SF3 ALPHA-1-ACID GLYCOPROTEIN ALPHA-1-ACID GLYCOPROTEIN 2 immune response#GO:0006955;inflammatory response#GO:0006954;immune system process#GO:0002376;response to stress#GO:0006950;acute inflammatory response#GO:0002526;defense response#GO:0006952;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015758.3|UniProtKB=A0A2I2ZRJ9 A0A2I2ZRJ9 LDHB PTHR43128:SF35 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE B CHAIN oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000001756.3|UniProtKB=G3RLX8 G3RLX8 SOX9 PTHR45803:SF1 SOX100B TRANSCRIPTION FACTOR SOX-9 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 gliogenesis#GO:0042063;morphogenesis of an epithelium#GO:0002009;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of cell differentiation#GO:0045597;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;heart development#GO:0007507;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;skeletal system development#GO:0001501;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;negative regulation of biological process#GO:0048519;connective tissue development#GO:0061448;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;tissue development#GO:0009888;chondrocyte differentiation#GO:0002062;oligodendrocyte differentiation#GO:0048709;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cartilage development#GO:0051216;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000025999.2|UniProtKB=A0A2I2Z5M5 A0A2I2Z5M5 PTHR24135:SF3 SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 1 signaling receptor complex adaptor activity#GO:0030159;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 multicellular organismal process#GO:0032501;cell junction organization#GO:0034330;cellular process#GO:0009987;cellular component organization#GO:0016043;system process#GO:0003008;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;nervous system process#GO:0050877;cognition#GO:0050890 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;dendritic spine#GO:0043197;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynaptic membrane#GO:0045211;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447 scaffold/adaptor protein#PC00226 Ionotropic glutamate receptor pathway#P00037>PSD95#P00999 GORGO|Ensembl=ENSGGOG00000002908.3|UniProtKB=G3QK90 G3QK90 LOC101135135 PTHR24070:SF407 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY SMALL MONOMERIC GTPASE hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;Ras protein signal transduction#GO:0007265;regulation of secretion#GO:0051046;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;cellular response to stimulus#GO:0051716;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000011927.3|UniProtKB=A0A2I2YUF7 A0A2I2YUF7 CEP63 PTHR18875:SF7 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO CENTROSOMAL PROTEIN OF 63 KDA cell differentiation#GO:0030154;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cellular component assembly#GO:0022607;cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;developmental process#GO:0032502;chromosome segregation#GO:0007059 intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000008011.4|UniProtKB=G3QYB2 G3QYB2 THSD7A PTHR11311:SF8 SPONDIN THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7A cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000015966.3|UniProtKB=G3RIQ6 G3RIQ6 OPTC PTHR46269:SF4 EPIPHYCAN-RELATED OPTICIN bone development#GO:0060348;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;connective tissue development#GO:0061448;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;system development#GO:0048731;external encapsulating structure organization#GO:0045229;cartilage development#GO:0051216 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 GORGO|Ensembl=ENSGGOG00000011828.3|UniProtKB=G3R834 G3R834 GABRR3 PTHR18945:SF196 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-3 signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;molecular transducer activity#GO:0060089;monoatomic anion channel activity#GO:0005253;ligand-gated monoatomic ion channel activity#GO:0015276 transport#GO:0006810;chloride transport#GO:0006821;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic anion transmembrane transport#GO:0098656;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916 cell junction#GO:0030054;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000026104.2|UniProtKB=G3S4X5 G3S4X5 MAGED1 PTHR11736:SF28 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN D1 negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008733.3|UniProtKB=G3R061 G3R061 DDRGK1 PTHR48176:SF4 DDRGK DOMAIN-CONTAINING PROTEIN 1 DDRGK DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;connective tissue development#GO:0061448;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of cellular response to stress#GO:0080135;system development#GO:0048731;cartilage development#GO:0051216;negative regulation of cell communication#GO:0010648;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;regulation of response to endoplasmic reticulum stress#GO:1905897;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 GORGO|Ensembl=ENSGGOG00000013064.3|UniProtKB=A0A2I2YYW0 A0A2I2YYW0 MEF2A PTHR11945:SF637 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2A sequence-specific DNA binding#GO:0043565;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;sequence-specific double-stranded DNA binding#GO:1990837;histone deacetylase binding#GO:0042826;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;Oxidative stress response#P00046>MEF-2#P01128 GORGO|Ensembl=ENSGGOG00000005818.3|UniProtKB=G3QSQ4 G3QSQ4 ABRAXAS1 PTHR31728:SF2 ABRAXAS FAMILY MEMBER BRCA1-A COMPLEX SUBUNIT ABRAXAS 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;microtubule binding#GO:0008017;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;attachment of spindle microtubules to kinetochore#GO:0008608;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;nuclear division#GO:0000280;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;localization#GO:0051179;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;organelle localization#GO:0051640 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Gene=MT-CO2|UniProtKB=P26456 P26456 MT-CO2 PTHR22888:SF9 CYTOCHROME C OXIDASE, SUBUNIT II CYTOCHROME C OXIDASE SUBUNIT 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 oxidoreductase#PC00176 Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06899;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06686;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#P06734 GORGO|Ensembl=ENSGGOG00000042537.1|UniProtKB=A0A2I2Z0U8 A0A2I2Z0U8 PTHR23266:SF359 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000036391.1|UniProtKB=A0A2I2YHT3 A0A2I2YHT3 ANKRD66 PTHR24180:SF48 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN 66 kinase modulator#PC00140;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000014202.3|UniProtKB=G3RE74 G3RE74 TMEM205 PTHR46916:SF2 TRANSMEMBRANE PROTEIN 205 TRANSMEMBRANE PROTEIN 205 GORGO|Ensembl=ENSGGOG00000010025.3|UniProtKB=G3R3F6 G3R3F6 CABP4 PTHR45917:SF4 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 4 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246 system process#GO:0003008;response to external stimulus#GO:0009605;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;cell communication#GO:0007154;response to abiotic stimulus#GO:0009628;sensory perception of light stimulus#GO:0050953;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;visual perception#GO:0007601;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;sensory perception of sound#GO:0007605;signaling#GO:0023052 GORGO|Ensembl=ENSGGOG00000014333.3|UniProtKB=G3REJ2 G3REJ2 TAGLN PTHR47385:SF16 CALPONIN TRANSGELIN cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000005711.3|UniProtKB=A0A2I2ZBJ3 A0A2I2ZBJ3 TMEM196 PTHR28681:SF1 TRANSMEMBRANE PROTEIN 196 TRANSMEMBRANE PROTEIN 196 GORGO|Ensembl=ENSGGOG00000004383.3|UniProtKB=G3QP13 G3QP13 NR2E3 PTHR24083:SF4 NUCLEAR HORMONE RECEPTOR PHOTORECEPTOR-SPECIFIC NUCLEAR RECEPTOR nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000007927.3|UniProtKB=A0A2I2YX42 A0A2I2YX42 ZNHIT3 PTHR13483:SF11 BOX C_D SNORNA PROTEIN 1-RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002815.3|UniProtKB=G3RZQ7 G3RZQ7 ZFP90 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000023683.2|UniProtKB=G3RY21 G3RY21 PTHR14948:SF21 NG5 PROLINE-RICH TRANSMEMBRANE PROTEIN 1 molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010120.3|UniProtKB=G3R3P2 G3R3P2 TMEM186 PTHR13603:SF1 TRANSMEMBRANE PROTEIN 186 TRANSMEMBRANE PROTEIN 186 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000043759.1|UniProtKB=A0A2I2Z848 A0A2I2Z848 PTHR23232:SF112 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 726 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002982.3|UniProtKB=G3QKF7 G3QKF7 TNFAIP8 PTHR12757:SF3 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Huntington disease#P00029>FIP-2#P00772 GORGO|Ensembl=ENSGGOG00000011391.3|UniProtKB=A0A2I2ZDB4 A0A2I2ZDB4 ERG PTHR11849:SF216 ETS TRANSCRIPTIONAL REGULATOR ERG transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000009399.3|UniProtKB=G3S532 G3S532 FNIP2 PTHR21634:SF11 RE13835P FOLLICULIN-INTERACTING PROTEIN 2 protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000004836.3|UniProtKB=G3SFM5 G3SFM5 TMPRSS2 PTHR24253:SF89 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 2 catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000005691.3|UniProtKB=G3QSE1 G3QSE1 TRANK1 PTHR21529:SF4 MAMMARY TURMOR VIRUS RECEPTOR HOMOLOG 1, 2 MTVR1, 2 TPR AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000008877.3|UniProtKB=G3R0I9 G3R0I9 PYY PTHR10533:SF14 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PEPTIDE YY-RELATED molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;neuropeptide hormone activity#GO:0005184;G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 G protein-coupled receptor signaling pathway#GO:0007186;feeding behavior#GO:0007631;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000025856.2|UniProtKB=G3S153 G3S153 CRADD PTHR15034:SF6 DEATH DOMAIN-CONTAINING PROTEIN CRADD DEATH DOMAIN-CONTAINING PROTEIN CRADD protein binding#GO:0005515;enzyme binding#GO:0019899;protease binding#GO:0002020;binding#GO:0005488 cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;signal transduction by p53 class mediator#GO:0072331;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to stress#GO:0006950;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Apoptosis signaling pathway#P00006>RAIDD#P00294 GORGO|Ensembl=ENSGGOG00000040350.1|UniProtKB=G3QFC3 G3QFC3 PTHR23413:SF26 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N RIBOSOMAL PROTEIN L32 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000022963.2|UniProtKB=G3RN90 G3RN90 LOC101142986 PTHR26453:SF589 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1A1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010394.3|UniProtKB=G3R4D9 G3R4D9 KLHL6 PTHR24412:SF428 KELCH PROTEIN KELCH-LIKE PROTEIN 6 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000690.3|UniProtKB=A0A2I2YR21 A0A2I2YR21 NKAPL PTHR13087:SF3 NF-KAPPA B ACTIVATING PROTEIN NKAP-LIKE PROTEIN regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000006174.3|UniProtKB=G3QTL2 G3QTL2 OXNAD1 PTHR46505:SF1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000002694.3|UniProtKB=G3QJQ0 G3QJQ0 FRS3 PTHR21258:SF39 DOCKING PROTEIN RELATED FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 3 signaling adaptor activity#GO:0035591;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;protein-macromolecule adaptor activity#GO:0030674;fibroblast growth factor receptor binding#GO:0005104;receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;growth factor receptor binding#GO:0070851 signaling#GO:0023052;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;cell surface receptor signaling pathway#GO:0007166;response to fibroblast growth factor#GO:0071774 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>FRS-2#P00240;FGF signaling pathway#P00021>FRS2#P00635 GORGO|Ensembl=ENSGGOG00000001482.3|UniProtKB=A0A2I2YR45 A0A2I2YR45 TMEM208 PTHR13505:SF7 TRANSMEMBRANE PROTEIN 208 TRANSMEMBRANE PROTEIN 208 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 GORGO|Ensembl=ENSGGOG00000015259.3|UniProtKB=G3RGX6 G3RGX6 ORMDL1 PTHR12665:SF12 ORMDL PROTEINS ORM1-LIKE PROTEIN 1 lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;cellular process#GO:0009987;homeostatic process#GO:0042592;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000004413.3|UniProtKB=A0A2I2ZPG3 A0A2I2ZPG3 FFAR4 PTHR24241:SF67 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR FREE FATTY ACID RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000010447.3|UniProtKB=A0A2I2Z7H6 A0A2I2Z7H6 PTHR11955:SF144 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 5-LIKE PROTEIN 3-RELATED ion binding#GO:0043167;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289 monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000039942.1|UniProtKB=A0A2I2ZU81 A0A2I2ZU81 ZNF322 PTHR24384:SF232 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 322 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007210.3|UniProtKB=G3QWA3 G3QWA3 TMEM38B PTHR12454:SF5 TRIMERIC INTRACELLULAR CATION CHANNEL TRIMERIC INTRACELLULAR CATION CHANNEL TYPE B passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;transport#GO:0006810;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;cytoplasm#GO:0005737;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000016534.3|UniProtKB=G3RK71 G3RK71 BAG1 PTHR12329:SF52 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008 membrane#GO:0016020;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 Apoptosis signaling pathway#P00006>Bag#P00278 GORGO|Gene=ANG|UniProtKB=Q71MJ0 Q71MJ0 ANG PTHR11437:SF60 RIBONUCLEASE ANGIOGENIN catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 response to bacterium#GO:0009617;anatomical structure development#GO:0048856;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;system development#GO:0048731;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;response to external biotic stimulus#GO:0043207;developmental process#GO:0032502;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune response#GO:0006955;multicellular organismal process#GO:0032501;response to other organism#GO:0051707;tube development#GO:0035295;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;defense response to bacterium#GO:0042742;angiogenesis#GO:0001525;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;defense response to Gram-positive bacterium#GO:0050830;circulatory system development#GO:0072359;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;multicellular organism development#GO:0007275;antibacterial humoral response#GO:0019731;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007341.3|UniProtKB=G3QWM5 G3QWM5 ARHGAP31 PTHR15729:SF3 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 31 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cell leading edge#GO:0031252;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000005039.3|UniProtKB=G3RY98 G3RY98 FBXW4 PTHR14381:SF1 DACTYLIN F-BOX_WD REPEAT-CONTAINING PROTEIN 4 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to stress#GO:0006950;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000009089.3|UniProtKB=A0A2I2Z2E6 A0A2I2Z2E6 ASB5 PTHR24136:SF18 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 5 biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;metabolic process#GO:0008152;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;positive regulation of protein metabolic process#GO:0051247;protein modification by small protein conjugation or removal#GO:0070647 GORGO|Ensembl=ENSGGOG00000006504.3|UniProtKB=G3QUG1 G3QUG1 PTHR33618:SF1 39S RIBOSOMAL PROTEIN L53, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML53 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004616.3|UniProtKB=G3QPN1 G3QPN1 EHMT1 PTHR46307:SF2 G9A, ISOFORM B HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000009978.3|UniProtKB=G3R3B7 G3R3B7 ETV2 PTHR11849:SF209 ETS ETS TRANSLOCATION VARIANT 2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Gene=CAV1|UniProtKB=Q2IBF0 Q2IBF0 CAV1 PTHR10844:SF18 CAVEOLIN CAVEOLIN-1 protein binding#GO:0005515;enzyme binding#GO:0019899;transmembrane transporter binding#GO:0044325;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;monoatomic ion homeostasis#GO:0050801;negative regulation of cell population proliferation#GO:0008285;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;negative regulation of biological process#GO:0048519;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;regulation of cytosolic calcium ion concentration#GO:0051480;plasma membrane organization#GO:0007009;regulation of cell population proliferation#GO:0042127;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 cell periphery#GO:0071944;caveola#GO:0005901;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;membrane microdomain#GO:0098857;Golgi apparatus#GO:0005794;sarcolemma#GO:0042383;cell junction#GO:0030054;vesicle#GO:0031982;membrane raft#GO:0045121;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane raft#GO:0044853 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>Caveolin-1#P06763;Integrin signalling pathway#P00034>Caveolin#P00918 GORGO|Ensembl=ENSGGOG00000000732.3|UniProtKB=G3QEM4 G3QEM4 STX6 PTHR19957:SF104 SYNTAXIN SYNTAXIN-6 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;synapse#GO:0045202;cellular anatomical structure#GO:0110165;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 SNARE protein#PC00034 Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074 GORGO|Ensembl=ENSGGOG00000008686.3|UniProtKB=G3R015 G3R015 TRAPPC6A PTHR12817:SF2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6A cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;cis-Golgi network#GO:0005801;intracellular protein-containing complex#GO:0140535;Golgi apparatus subcompartment#GO:0098791;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;trans-Golgi network#GO:0005802 GORGO|Ensembl=ENSGGOG00000022570.2|UniProtKB=G3S8N6 G3S8N6 PTHR10836:SF124 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000006668.3|UniProtKB=G3QUW0 G3QUW0 MRPL28 PTHR13528:SF3 39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000333.3|UniProtKB=G3QDK6 G3QDK6 MRPL23 PTHR12059:SF5 RIBOSOMAL PROTEIN L23-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005773.3|UniProtKB=G3QSL5 G3QSL5 USHBP1 PTHR23347:SF5 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED HARMONIN-BINDING PROTEIN USHBP1 GORGO|Ensembl=ENSGGOG00000037860.1|UniProtKB=A0A2I2YNU9 A0A2I2YNU9 PTHR43160:SF3 ACONITATE HYDRATASE B ACONITATE HYDRATASE, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;iron-sulfur cluster binding#GO:0051536 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829 hydratase#PC00120;lyase#PC00144 TCA cycle#P00051>Aconitase#P01268 GORGO|Ensembl=ENSGGOG00000028106.2|UniProtKB=G3RWF7 G3RWF7 LMBR1L PTHR12625:SF2 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR PROTEIN LMBR1L signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;localization#GO:0051179;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000024121.2|UniProtKB=G3SF27 G3SF27 LOC101151182 PTHR10605:SF7 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 3B1 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000014329.4|UniProtKB=A0A2I2ZQA5 A0A2I2ZQA5 PTHR11909:SF451 CASEIN KINASE-RELATED TAU-TUBULIN KINASE 2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cilium assembly#GO:0060271;cellular component organization#GO:0016043;signaling#GO:0023052;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;cilium organization#GO:0044782;cell communication#GO:0007154;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000010916.3|UniProtKB=P84349 P84349 BGLAP PTHR14235:SF0 OSTEOCALCIN OSTEOCALCIN small molecule binding#GO:0036094;binding#GO:0005488;structural molecule activity#GO:0005198 cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;ossification#GO:0001503;bone development#GO:0060348;cellular process#GO:0009987;system development#GO:0048731;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;animal organ development#GO:0048513;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;developmental process#GO:0032502;osteoblast differentiation#GO:0001649;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014252.3|UniProtKB=G3REC0 G3REC0 RAB11A PTHR47979:SF110 DRAB11-RELATED RAS-RELATED PROTEIN RAB-11A purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168 intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;endosome to plasma membrane protein transport#GO:0099638;vesicle localization#GO:0051648;biological regulation#GO:0065007;organelle localization#GO:0051640;protein localization to cell junction#GO:1902414;pigmentation#GO:0043473;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;secretion#GO:0046903;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;intracellular protein transport#GO:0006886;protein localization to synapse#GO:0035418;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;endosomal transport#GO:0016197;exocytosis#GO:0006887;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular pigmentation#GO:0033059;establishment of vesicle localization#GO:0051650;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;protein transport#GO:0015031;secretion by cell#GO:0032940;protein localization to membrane#GO:0072657;establishment of organelle localization#GO:0051656;endocytic recycling#GO:0032456;export from cell#GO:0140352 organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cell junction#GO:0030054;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000003845.3|UniProtKB=G3SH78 G3SH78 DENND4B PTHR12296:SF18 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN 4B guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000008562.3|UniProtKB=G3QZQ2 G3QZQ2 ATP6V1G3 PTHR12713:SF5 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G 3 organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;developmental maturation#GO:0021700;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;developmental process#GO:0032502;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;synaptic vesicle maturation#GO:0016188;proton transmembrane transport#GO:1902600;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular homeostasis#GO:0019725;cellular component organization#GO:0016043;homeostatic process#GO:0042592;transmembrane transport#GO:0055085;cellular localization#GO:0051641;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane protein complex#GO:0098796;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;cation-transporting ATPase complex#GO:0090533;synaptic vesicle#GO:0008021;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;ATPase complex#GO:1904949;ATPase dependent transmembrane transport complex#GO:0098533;intracellular vesicle#GO:0097708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;proton-transporting two-sector ATPase complex#GO:0016469;cell junction#GO:0030054;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;secretory vesicle#GO:0099503;presynapse#GO:0098793;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vacuole#GO:0005773;cytoplasm#GO:0005737 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000023800.2|UniProtKB=G3RQY3 G3RQY3 FAM241A PTHR33690:SF1 DUF4605 DOMAIN-CONTAINING PROTEIN FAMILY WITH SEQUENCE SIMILARITY 241 MEMBER A intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000008114.3|UniProtKB=G3QYJ5 G3QYJ5 THEM4 PTHR12418:SF19 ACYL-COENZYME A THIOESTERASE THEM4 ACYL-COENZYME A THIOESTERASE THEM4 fatty acyl-CoA hydrolase activity#GO:0047617;deacylase activity#GO:0160215;catalytic activity#GO:0003824;acyl-CoA hydrolase activity#GO:0016289;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;regulation of membrane permeability#GO:0090559;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of biological quality#GO:0065008;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;cell death#GO:0008219;apoptotic process#GO:0006915;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;carboxylic acid metabolic process#GO:0019752;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000008985.3|UniProtKB=G3R0T6 G3R0T6 FPR3 PTHR24225:SF16 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 3 peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;regulation of biological quality#GO:0065008;cell communication#GO:0007154;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000000871.3|UniProtKB=G3QF00 G3QF00 LOC101130559 PTHR26453:SF136 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000042963.1|UniProtKB=A0A2I2ZWW8 A0A2I2ZWW8 LOC101137955 PTHR24381:SF437 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000006818.3|UniProtKB=A0A2I2Z8G4 A0A2I2Z8G4 LAMTOR2 PTHR13323:SF4 LATE ENDOSOMAL/LYSOSOMAL MP1 INTERACTING PROTEIN RAGULATOR COMPLEX PROTEIN LAMTOR2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to acid chemical#GO:0001101;positive regulation of biological process#GO:0048518;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887 vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 GORGO|Ensembl=ENSGGOG00000005925.3|UniProtKB=G3QSZ7 G3QSZ7 OTUD6A PTHR12419:SF13 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 6A catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000011857.3|UniProtKB=G3R859 G3R859 PTHR11681:SF2 NEUROPHYSIN OXYTOCIN-NEUROPHYSIN 1 PROPROTEIN neuropeptide hormone activity#GO:0005184;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of system process#GO:0044057;regulation of smooth muscle contraction#GO:0006940;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of muscle system process#GO:0090257;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of muscle contraction#GO:0006937;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 peptide hormone#PC00179;neuropeptide#PC00162 Vasopressin synthesis#P04395>Pro-Neurophysin#P04591;Opioid prodynorphin pathway#P05916>provasopressin#P05999;Vasopressin synthesis#P04395>Vasopressin#P04590;Opioid prodynorphin pathway#P05916>prepropressophysin#G06048;Opioid prodynorphin pathway#P05916>prepropressophysin#G06050;Vasopressin synthesis#P04395>Glycopeptide#P04593;Vasopressin synthesis#P04395>Signal Peptide#P04597;Vasopressin synthesis#P04395>Pro-Vasopressin#P04598;Vasopressin synthesis#P04395>Pro2-Vasopressin#P04595;Vasopressin synthesis#P04395>Neurophysin#P04594;Opioid prodynorphin pathway#P05916>vasopressin#P06000 GORGO|Ensembl=ENSGGOG00000012590.3|UniProtKB=G3RA33 G3RA33 LMO7 PTHR46767:SF1 LIM DOMAIN ONLY PROTEIN 7 LIM DOMAIN ONLY PROTEIN 7 GORGO|Ensembl=ENSGGOG00000014979.3|UniProtKB=G3RG73 G3RG73 CD177 PTHR16529:SF8 CD177 ANTIGEN CD177 ANTIGEN membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853;cell periphery#GO:0071944;membrane#GO:0016020;membrane raft#GO:0045121;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 GORGO|Ensembl=ENSGGOG00000014040.3|UniProtKB=G3RDT2 G3RDT2 TMEM212 PTHR23320:SF130 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED TRANSMEMBRANE PROTEIN 212 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004507.3|UniProtKB=G3QPD3 G3QPD3 GLDC PTHR11773:SF1 GLYCINE DEHYDROGENASE, DECARBOXYLATING GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000024214.2|UniProtKB=A0A2I2YN10 A0A2I2YN10 SANBR PTHR20946:SF0 SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;immune system process#GO:0002376;B cell activation involved in immune response#GO:0002312;animal gross anatomical part developmental process#GO:0160108;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell activation involved in immune response#GO:0002263;immune system development#GO:0002520;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;lymphocyte activation involved in immune response#GO:0002285;cellular process#GO:0009987;somatic recombination of immunoglobulin gene segments#GO:0016447;lymphocyte activation#GO:0046649;gene expression#GO:0010467;DNA recombination#GO:0006310;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;B cell activation#GO:0042113;multicellular organism development#GO:0007275;somatic diversification of immune receptors#GO:0002200;leukocyte activation#GO:0045321;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell activation#GO:0001775;system development#GO:0048731;anatomical structure development#GO:0048856;immune response#GO:0006955;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;somatic cell DNA recombination#GO:0016444;adaptive immune response#GO:0002250;multicellular organismal process#GO:0032501;developmental process#GO:0032502;macromolecule metabolic process#GO:0043170 GORGO|Ensembl=ENSGGOG00000012289.4|UniProtKB=G3R9C0 G3R9C0 GRID1 PTHR18966:SF108 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, DELTA-1 neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267 postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuron spine#GO:0044309;postsynapse#GO:0098794;dendritic spine#GO:0043197;cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;dendrite#GO:0030425;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;signaling receptor complex#GO:0043235;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009525.3|UniProtKB=A0A2I2ZDA6 A0A2I2ZDA6 RTN4RL2 PTHR45617:SF168 LEUCINE RICH REPEAT FAMILY PROTEIN RETICULON 4 RECEPTOR LIKE 2 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013354.3|UniProtKB=G3RC04 G3RC04 NKIRAS1 PTHR46152:SF1 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 GORGO|Ensembl=ENSGGOG00000013544.3|UniProtKB=G3RCI5 G3RCI5 MID2 PTHR24099:SF12 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE MID2-RELATED binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 macromolecule localization#GO:0033036;protein localization to cytoskeleton#GO:0044380;intracellular protein localization#GO:0008104;protein localization to microtubule cytoskeleton#GO:0072698;localization#GO:0051179;protein localization to organelle#GO:0033365 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005182.3|UniProtKB=G3QR36 G3QR36 EVI2B PTHR15384:SF0 PROTEIN EVI2B PROTEIN EVI2B regulation of myeloid cell differentiation#GO:0045637;regulation of cell division#GO:0051302;regulation of hemopoiesis#GO:1903706;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of developmental process#GO:0050793;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of biological process#GO:0048518;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239 GORGO|Ensembl=ENSGGOG00000013411.3|UniProtKB=G3RC63 G3RC63 BRPF3 PTHR13793:SF19 PHD FINGER PROTEINS BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 3 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000013878.3|UniProtKB=G3RDD2 G3RDD2 SOX14 PTHR10270:SF107 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015782.3|UniProtKB=G3RIA4 G3RIA4 GLB1 PTHR23421:SF172 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052 lysosome#GO:0005764;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 galactosidase#PC00104;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000001304.3|UniProtKB=G3QG37 G3QG37 MRPL1 PTHR36427:SF5 54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000041317.1|UniProtKB=A0A2I2YUB1 A0A2I2YUB1 PTHR48012:SF8 STERILE20-LIKE KINASE, ISOFORM B-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of locomotion#GO:0040012;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000005197.4|UniProtKB=G3QR56 G3QR56 XRCC4 PTHR28559:SF2 DNA REPAIR PROTEIN XRCC4 DNA REPAIR PROTEIN XRCC4 response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;response to ionizing radiation#GO:0010212;V(D)J recombination#GO:0033151;response to abiotic stimulus#GO:0009628;immune system development#GO:0002520;cellular response to stress#GO:0033554;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;gene expression#GO:0010467;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;multicellular organism development#GO:0007275;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;system development#GO:0048731;anatomical structure development#GO:0048856;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;somatic cell DNA recombination#GO:0016444;multicellular organismal process#GO:0032501;macromolecule biosynthetic process#GO:0009059;response to radiation#GO:0009314;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;developmental process#GO:0032502;DNA damage response#GO:0006974;DNA repair#GO:0006281 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;DNA repair complex#GO:1990391;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000023738.3|UniProtKB=G3RXY5 G3RXY5 RASA2 PTHR10194:SF21 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 2 GTPase-activating protein#PC00257 FGF signaling pathway#P00021>RasGAP#P00646;PDGF signaling pathway#P00047>RasGAP#P01152;EGF receptor signaling pathway#P00018>GAP#P00546 GORGO|Ensembl=ENSGGOG00000014483.3|UniProtKB=G3REY0 G3REY0 CWH43 PTHR14859:SF1 CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR PGAP2-INTERACTING PROTEIN biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000016831.3|UniProtKB=G3RKY7 G3RKY7 PSENEN PTHR16318:SF1 GAMMA-SECRETASE SUBUNIT PEN-2 GAMMA-SECRETASE SUBUNIT PEN-2 cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 Alzheimer disease-amyloid secretase pathway#P00003>Pen-2#P00089;Alzheimer disease-presenilin pathway#P00004>Pen-2#P00149 GORGO|Ensembl=ENSGGOG00000002720.3|UniProtKB=G3QJS7 G3QJS7 SPIN4 PTHR10405:SF9 SPINDLIN SPINDLIN-4 histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000027336.2|UniProtKB=G3S2Q6 G3S2Q6 KLK15 PTHR24271:SF60 KALLIKREIN-RELATED KALLIKREIN-15 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000004118.3|UniProtKB=G3S6E0 G3S6E0 TP53INP2 PTHR31671:SF2 DIABETES AND OBESITY REGULATED, ISOFORM G TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;protein-membrane adaptor activity#GO:0043495 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;organelle assembly#GO:0070925;regulation of RNA metabolic process#GO:0051252;vacuole organization#GO:0007033;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macroautophagy#GO:0016236;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;autophagosome#GO:0005776;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000006215.3|UniProtKB=G3S5A6 G3S5A6 GSTZ1 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;glutathione metabolic process#GO:0006749;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000004038.3|UniProtKB=G3QN58 G3QN58 OTX2 PTHR45793:SF2 HOMEOBOX PROTEIN HOMEOBOX PROTEIN OTX2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000004346.3|UniProtKB=G3QNY5 G3QNY5 TMEM171 PTHR31617:SF0 TRANSMEMBRANE PROTEIN 171 TRANSMEMBRANE PROTEIN 171 GORGO|Ensembl=ENSGGOG00000002630.3|UniProtKB=G3QJJ2 G3QJJ2 C1H1orf141 PTHR36873:SF1 HYPOTHETICAL GENE SUPPORTED BY BC079057 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 141 GORGO|Ensembl=ENSGGOG00000037551.1|UniProtKB=A0A2I2YD12 A0A2I2YD12 MOGS PTHR10412:SF11 MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 glucosidase#PC00108;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000025535.2|UniProtKB=G3RPF3 G3RPF3 LOC101152433 PTHR10956:SF4 60S RIBOSOMAL PROTEIN L31 LARGE RIBOSOMAL SUBUNIT PROTEIN EL31 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000002498.3|UniProtKB=G3QJ74 G3QJ74 CCL15 PTHR12015:SF77 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 15 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125 leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;cell migration#GO:0016477;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;chemotaxis#GO:0006935;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;regulation of cell motility#GO:2000145;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;response to cytokine#GO:0034097;response to chemical#GO:0042221;taxis#GO:0042330;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;response to peptide#GO:1901652;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000009876.3|UniProtKB=G3R333 G3R333 ZNF112 PTHR23226:SF466 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 235 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006424.3|UniProtKB=G3QU83 G3QU83 ERRFI1 PTHR14254:SF5 GENE 33 POLYPEPTIDE ERBB RECEPTOR FEEDBACK INHIBITOR 1 negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of signal transduction#GO:0009968;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein modification process#GO:0031399;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000016918.3|UniProtKB=G3RL78 G3RL78 SLC17A6 PTHR11662:SF201 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 2 L-amino acid transmembrane transporter activity#GO:0015179;acidic amino acid transmembrane transporter activity#GO:0015172;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943 vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter transport#GO:0006836;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;trans-synaptic signaling#GO:0099537 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133 secondary carrier transporter#PC00258 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 GORGO|Ensembl=ENSGGOG00000016882.3|UniProtKB=G3RL36 G3RL36 KRT13 PTHR23239:SF121 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 13 structural molecule activity#GO:0005198 supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000027243.2|UniProtKB=A0A2I2YC67 A0A2I2YC67 PTHR10502:SF199 ANNEXIN ANNEXIN phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;binding#GO:0005488 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;cell adhesion#GO:0007155;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of proteolysis#GO:0030162;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000001428.3|UniProtKB=G3QGF6 G3QGF6 CXADR PTHR44468:SF3 COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR-RELATED COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 homotypic cell-cell adhesion#GO:0034109;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;tight junction#GO:0070160;cell-cell contact zone#GO:0044291;apical junction complex#GO:0043296;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;cell-cell junction#GO:0005911;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;intercalated disc#GO:0014704;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;basal part of cell#GO:0045178 GORGO|Ensembl=ENSGGOG00000022559.2|UniProtKB=G3RW79 G3RW79 EFEMP1 PTHR24034:SF102 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 1 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000023791.2|UniProtKB=G3RQ17 G3RQ17 LOC129529329 PTHR31678:SF3 KERATIN-ASSOCIATED PROTEIN 6-3 KERATIN-ASSOCIATED PROTEIN 6-2 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000007063.3|UniProtKB=G3RUT6 G3RUT6 KLHL26 PTHR45632:SF13 LD33804P KELCH-LIKE PROTEIN 26 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022706.2|UniProtKB=G3SET6 G3SET6 LOC101134092 PTHR12015:SF206 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 2 cytokine#PC00083 CCKR signaling map#P06959>CXCL2#G07265;CCKR signaling map#P06959>CXCL2#G06972 GORGO|Ensembl=ENSGGOG00000025967.2|UniProtKB=G3S6C9 G3S6C9 CLEC11A PTHR22799:SF1 TETRANECTIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 11 MEMBER A signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 ossification#GO:0001503;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000001971.3|UniProtKB=G3QHV4 G3QHV4 PRR36 PTHR22427:SF8 GH15728P PROLINE-RICH PROTEIN 36 GORGO|Ensembl=ENSGGOG00000023372.2|UniProtKB=G3S7P1 G3S7P1 AASDH PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012877.3|UniProtKB=G3RXB4 G3RXB4 RAB5IF PTHR12906:SF0 PROTEIN C20ORF24 RAB5-INTERACTING PROTEIN GEL COMPLEX SUBUNIT OPTI GORGO|Ensembl=ENSGGOG00000015469.3|UniProtKB=G3SA29 G3SA29 LOC101136934 PTHR11412:SF174 MACROGLOBULIN / COMPLEMENT OVOSTATIN HOMOLOG 1-RELATED molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 response to stimulus#GO:0050896;defense response#GO:0006952;response to stress#GO:0006950;inflammatory response#GO:0006954 catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000002958.3|UniProtKB=G3QKD5 G3QKD5 ILDR1 PTHR15923:SF3 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING RECEPTOR 1 cargo receptor activity#GO:0038024 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000007495.3|UniProtKB=G3QX09 G3QX09 USP21 PTHR21646:SF6 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000022309.2|UniProtKB=G3SBT5 G3SBT5 MAL2 PTHR22776:SF42 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PROTEIN MAL2 regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007 vesicle#GO:0031982;membrane#GO:0016020;membrane raft#GO:0045121;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane microdomain#GO:0098857;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000491.3|UniProtKB=G3QE00 G3QE00 ATPAF2 PTHR21013:SF10 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000005986.3|UniProtKB=G3QT49 G3QT49 RLIG1 PTHR31219:SF2 CHROMOSOME 28 C12ORF29 HOMOLOG RNA LIGASE 1 GORGO|Ensembl=ENSGGOG00000036909.1|UniProtKB=A0A2I2ZAR1 A0A2I2ZAR1 SMCO1 PTHR35979:SF1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000028076.2|UniProtKB=G3RPV8 G3RPV8 IGSF6 PTHR15297:SF2 IMMUNOGLOBULIN SUPERFAMILY MEMBER 6 IMMUNOGLOBULIN SUPERFAMILY MEMBER 6 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000008661.3|UniProtKB=G3QZZ7 G3QZZ7 TMEM132A PTHR13388:SF9 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132A positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of signal transduction#GO:0009967;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000023434.2|UniProtKB=A0A2I2Z1R8 A0A2I2Z1R8 PTHR45722:SF5 60S RIBOSOMAL PROTEIN L35 LARGE RIBOSOMAL SUBUNIT PROTEIN UL29 RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;mRNA binding#GO:0003729 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000037032.1|UniProtKB=A0A2I2Y2B9 A0A2I2Y2B9 FAM237B PTHR36690:SF1 PROTEIN FAM237A PROTEIN FAM237B GORGO|Ensembl=ENSGGOG00000021955.2|UniProtKB=G3SDD0 G3SDD0 PTHR24166:SF30 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 63 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015815.3|UniProtKB=G3RIC6 G3RIC6 METTL21A PTHR14614:SF14 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-LYSINE METHYLTRANSFERASE METTL21A S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000014844.3|UniProtKB=A0A2I2Y8M7 A0A2I2Y8M7 COMMD4 PTHR16231:SF11 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 4 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;response to peptide#GO:1901652;response to tumor necrosis factor#GO:0034612;cellular process#GO:0009987;signal transduction#GO:0007165;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000010433.3|UniProtKB=G3R4H7 G3R4H7 VPS26A PTHR12233:SF4 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26A intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cytosolic transport#GO:0016482 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;retromer complex#GO:0030904;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012764.3|UniProtKB=G3RAI3 G3RAI3 CDHR1 PTHR24026:SF121 FAT ATYPICAL CADHERIN-RELATED CADHERIN-RELATED FAMILY MEMBER 1 plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;axon development#GO:0061564;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000022254.2|UniProtKB=A0A2I2YBS9 A0A2I2YBS9 PTHR21258:SF57 DOCKING PROTEIN RELATED IRS-TYPE PTB DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012534.3|UniProtKB=G3R9Y1 G3R9Y1 LOC101141497 PTHR15168:SF0 CYTOCHROME B-245 LIGHT CHAIN CYTOCHROME B-245 LIGHT CHAIN catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 immune system process#GO:0002376;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;superoxide metabolic process#GO:0006801;defense response#GO:0006952;response to external stimulus#GO:0009605;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;immune response#GO:0006955;defense response to symbiont#GO:0140546 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000027286.2|UniProtKB=G3RMK1 G3RMK1 LOC101141666 PTHR31980:SF2 PROTEIN FAM220A PROTEIN FAM220BP-RELATED nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000023215.2|UniProtKB=A0A2I2YLX3 A0A2I2YLX3 PTHR10131:SF135 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular adaptor activity#GO:0060090;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;signaling adaptor activity#GO:0035591;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;protein-macromolecule adaptor activity#GO:0030674 cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;defense response#GO:0006952;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;innate immune response#GO:0045087;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response#GO:0006955;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to bacterium#GO:0009617;lipopolysaccharide-mediated signaling pathway#GO:0031663;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;side of membrane#GO:0098552;cell junction#GO:0030054;cytoplasmic side of membrane#GO:0098562 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013694.3|UniProtKB=G3RCX1 G3RCX1 AHRR PTHR10649:SF3 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR REPRESSOR transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000009727.3|UniProtKB=G3R2Q0 G3R2Q0 PACS1 PTHR13280:SF16 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 1 protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to plasma membrane#GO:0072659;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to Golgi apparatus#GO:0034067;protein localization to cell periphery#GO:1990778 GORGO|Ensembl=ENSGGOG00000009340.3|UniProtKB=G3R1P9 G3R1P9 SLC5A12 PTHR42985:SF15 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 2 monocarboxylic acid transmembrane transporter activity#GO:0008028;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293 metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transport#GO:0006810;sodium ion transport#GO:0006814 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000041514.1|UniProtKB=A0A2I2Z8B0 A0A2I2Z8B0 PTHR10792:SF30 60S RIBOSOMAL PROTEIN L24 TRASH DOMAIN-CONTAINING PROTEIN ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007354.3|UniProtKB=G3SFP7 G3SFP7 PDE7A PTHR11347:SF96 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 7A hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000005615.3|UniProtKB=G3QS73 G3QS73 ARG2 PTHR43782:SF4 ARGINASE ARGINASE-2, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;hydrolase activity#GO:0016787;metal ion binding#GO:0046872 negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;regulation of multicellular organismal process#GO:0051239;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;oxoacid metabolic process#GO:0043436;regulation of biological process#GO:0050789;carboxylic acid metabolic process#GO:0019752;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;regulation of macromolecule metabolic process#GO:0060255 mitochondrion#GO:0005739;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000004661.3|UniProtKB=G3QPR7 G3QPR7 SLC1A3 PTHR11958:SF24 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 1 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943 carboxylic acid transport#GO:0046942;transport#GO:0006810;acidic amino acid transport#GO:0015800;C4-dicarboxylate transport#GO:0015740;amino acid transport#GO:0006865;organic acid transport#GO:0015849;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;aspartate transmembrane transport#GO:0015810;L-amino acid transport#GO:0015807;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;L-glutamate import#GO:0051938;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 GORGO|Ensembl=ENSGGOG00000039836.1|UniProtKB=A0A2I2ZQB6 A0A2I2ZQB6 ATXN7L3B PTHR47733:SF1 ATAXIN-7 LIKE PROTEIN 3B, ATXN7L3B ATAXIN-7-LIKE PROTEIN 3B regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000002027.3|UniProtKB=G3QI05 G3QI05 LOC101125308 PTHR10281:SF4 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUFERRICIN cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000513.3|UniProtKB=A0A2I2Y7Z2 A0A2I2Y7Z2 SMARCA2 PTHR10799:SF541 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000036220.1|UniProtKB=A0A2I2YST1 A0A2I2YST1 PTHR23147:SF5 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 10 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000010779.3|UniProtKB=G3R5D9 G3R5D9 EXOG PTHR13966:SF23 ENDONUCLEASE RELATED NUCLEASE EXOG, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;exonuclease activity#GO:0004527;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;catabolic process#GO:0009056 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;mitochondrial membrane#GO:0031966;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000037187.1|UniProtKB=A0A2I2YEF9 A0A2I2YEF9 PTHR12383:SF32 PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endopeptidase complex#GO:1905369;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000015356.3|UniProtKB=G3RH64 G3RH64 PRPSAP2 PTHR10210:SF29 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 2 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000009419.3|UniProtKB=G3R1X4 G3R1X4 NARS1 PTHR22594:SF16 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000007665.3|UniProtKB=G3QXF8 G3QXF8 LPCAT4 PTHR23063:SF7 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHOLIPID ACYLTRANSFERASE LPCAT4 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000011355.3|UniProtKB=A0A2I2ZH54 A0A2I2ZH54 ZNF862 PTHR46880:SF3 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 862 GORGO|Ensembl=ENSGGOG00000008683.3|UniProtKB=A0A2I2ZXU3 A0A2I2ZXU3 PFKFB3 PTHR10606:SF41 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 3 phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;sugar-phosphatase activity#GO:0050308 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 carbohydrate phosphatase#PC00066;hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000038696.1|UniProtKB=A0A2I2Z4C5 A0A2I2Z4C5 SLC6A18 PTHR11616:SF109 SODIUM/CHLORIDE DEPENDENT TRANSPORTER INACTIVE SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT3 sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 GORGO|Ensembl=ENSGGOG00000025448.2|UniProtKB=G3SHI4 G3SHI4 PTHR43888:SF8 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 1 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;ATPase activator activity#GO:0001671 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;response to stress#GO:0006950;macromolecule localization#GO:0033036;response to heat#GO:0009408;cellular response to heat#GO:0034605;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;metabolic process#GO:0008152;protein localization to organelle#GO:0033365;response to stimulus#GO:0050896;protein folding#GO:0006457;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;protein localization to mitochondrion#GO:0070585;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;localization#GO:0051179;protein refolding#GO:0042026;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000027701.2|UniProtKB=A0A2I2YGJ1 A0A2I2YGJ1 KLK12 PTHR24271:SF63 KALLIKREIN-RELATED KALLIKREIN-12 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000008466.3|UniProtKB=G3QZG6 G3QZG6 SHOC2 PTHR48051:SF33 FAMILY NOT NAMED LEUCINE-RICH REPEAT PROTEIN SHOC-2 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003374.3|UniProtKB=G3QLG5 G3QLG5 PTHR12276:SF16 EPSIN/ENT-RELATED EPSIN-3 clathrin binding#GO:0030276;phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289;protein binding#GO:0005515 localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583 intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vesicle coat#GO:0030120;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012298.3|UniProtKB=G3R9D5 G3R9D5 SLC4A8 PTHR11453:SF37 ANION EXCHANGE PROTEIN ELECTRONEUTRAL SODIUM BICARBONATE EXCHANGER 1 active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;chloride transmembrane transporter activity#GO:0015108;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000015033.3|UniProtKB=G3RGD5 G3RGD5 FAM149B1 PTHR31997:SF0 AGAP003710-PA PRIMARY CILIUM ASSEMBLY PROTEIN FAM149B1 plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365 GORGO|Ensembl=ENSGGOG00000009345.3|UniProtKB=G3R1Q6 G3R1Q6 HGS PTHR46275:SF1 HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 endocytic recycling#GO:0032456;endocytosis#GO:0006897;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;receptor internalization#GO:0031623;vesicle-mediated transport to the plasma membrane#GO:0098876;receptor-mediated endocytosis#GO:0006898;endosomal transport#GO:0016197;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013254.3|UniProtKB=G3RBR6 G3RBR6 CNNM2 PTHR12064:SF22 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM2 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;magnesium ion transmembrane transporter activity#GO:0015095;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic ion homeostasis#GO:0050801 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000011570.3|UniProtKB=G3R7F3 G3R7F3 PTHR15241:SF394 TRANSFORMER-2-RELATED POLYADENYLATE-BINDING PROTEIN RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000011625.3|UniProtKB=G3R7K5 G3R7K5 PTHR14392:SF3 NIBAN FAMILY MEMBER PROTEIN NIBAN 1 GORGO|Ensembl=ENSGGOG00000024881.2|UniProtKB=G3RMP1 G3RMP1 UBE2S PTHR24068:SF126 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 S ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000003503.3|UniProtKB=G3QLT7 G3QLT7 COPA PTHR19876:SF1 COATOMER COATOMER SUBUNIT ALPHA retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 vesicle membrane#GO:0012506;membrane#GO:0016020;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000015747.3|UniProtKB=G3RI72 G3RI72 PSMD14 PTHR10410:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED UBIQUITIN C-TERMINAL HYDROLASE PSMD14 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;proteasome complex#GO:0000502;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation factor#PC00223;translation initiation factor#PC00224 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 GORGO|Ensembl=ENSGGOG00000005289.3|UniProtKB=A0A2I2Z700 A0A2I2Z700 TSHZ1 PTHR12487:SF6 TEASHIRT-RELATED TEASHIRT HOMOLOG 1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000017098.3|UniProtKB=G3RLN1 G3RLN1 SLC15A5 PTHR11654:SF91 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002420.3|UniProtKB=A0A2I2Y5W8 A0A2I2Y5W8 LOC101142657 PTHR38537:SF12 JITTERBUG, ISOFORM N FILAMIN-C GORGO|Ensembl=ENSGGOG00000005473.3|UniProtKB=G3QRU5 G3QRU5 MED11 PTHR22890:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015284.3|UniProtKB=G3RGZ6 G3RGZ6 SOBP PTHR23186:SF2 RETINOIC ACID-INDUCED PROTEIN 2 SINE OCULIS-BINDING PROTEIN HOMOLOG animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;developmental process#GO:0032502;sensory organ development#GO:0007423;embryo development#GO:0009790;multicellular organismal process#GO:0032501;inner ear development#GO:0048839;inner ear morphogenesis#GO:0042472;ear development#GO:0043583;anatomical structure development#GO:0048856;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000017030.3|UniProtKB=G3RLH2 G3RLH2 ZNF226 PTHR24377:SF1013 IP01015P-RELATED ZINC FINGER PROTEIN 234 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022881.2|UniProtKB=G3RRH2 G3RRH2 AZI2 PTHR14432:SF6 PROSAPIP2 PROTEIN/5-AZACYTIDINE INDUCED GENE 2 5-AZACYTIDINE-INDUCED PROTEIN 2 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000037631.1|UniProtKB=A0A2I2YMY2 A0A2I2YMY2 LOC101138588 PTHR11571:SF254 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 2 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000026283.2|UniProtKB=G3S551 G3S551 PTHR10827:SF78 RETICULOCALBIN RETICULOCALBIN-2 calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000015652.4|UniProtKB=A0A2I2YRM6 A0A2I2YRM6 DIP2C PTHR22754:SF33 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG C catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002590.3|UniProtKB=G3S960 G3S960 EMILIN1 PTHR15427:SF1 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-1 structural molecule activity#GO:0005198;protein binding#GO:0005515;extracellular matrix structural constituent#GO:0005201;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cell adhesion#GO:0030155;positive regulation of developmental process#GO:0051094;cell adhesion mediated by integrin#GO:0033627;regulation of vasculature development#GO:1901342;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of cell adhesion#GO:0045785;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;positive regulation of cell-substrate adhesion#GO:0010811;regulation of biological process#GO:0050789;positive regulation of angiogenesis#GO:0045766;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell adhesion#GO:0007155;regulation of angiogenesis#GO:0045765 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015069.3|UniProtKB=A0A2I2YYK5 A0A2I2YYK5 TREML1 PTHR11860:SF37 POLYMERIC-IMMUNOGLOBULIN RECEPTOR TREM-LIKE TRANSCRIPT 1 PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;coagulation#GO:0050817;cellular process#GO:0009987;response to wounding#GO:0009611;response to stress#GO:0006950;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;platelet activation#GO:0030168;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;hemostasis#GO:0007599;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;regulation of cellular process#GO:0050794;cell activation#GO:0001775;wound healing#GO:0042060;regulation of biological quality#GO:0065008;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000039494.1|UniProtKB=A0A2I2Y2N8 A0A2I2Y2N8 PTHR23105:SF186 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000026186.2|UniProtKB=G3RXT0 G3RXT0 CA8 PTHR18952:SF104 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of calcium-mediated signaling#GO:0050850;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000011168.3|UniProtKB=A0A2I2YMT4 A0A2I2YMT4 PLD5 PTHR10185:SF9 PHOSPHOLIPASE D - RELATED INACTIVE PHOSPHOLIPASE D5 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000010431.3|UniProtKB=G3R4H1 G3R4H1 ELOVL1 PTHR11157:SF19 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000013653.3|UniProtKB=G3RCT2 G3RCT2 SPESP1 PTHR31667:SF2 SPERM EQUATORIAL SEGMENT PROTEIN 1 SPERM EQUATORIAL SEGMENT PROTEIN 1 acrosome reaction#GO:0007340;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;cellular process#GO:0009987;single fertilization#GO:0007338;reproductive process#GO:0022414;fertilization#GO:0009566;cellular process involved in reproduction in multicellular organism#GO:0022412;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503 GORGO|Ensembl=ENSGGOG00000010231.3|UniProtKB=G3R3Z7 G3R3Z7 SHD PTHR15127:SF33 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN D binding#GO:0005488;protein binding#GO:0005515 GORGO|Ensembl=ENSGGOG00000002727.3|UniProtKB=G3QJT3 G3QJT3 KCND1 PTHR11537:SF174 VOLTAGE-GATED POTASSIUM CHANNEL A-TYPE VOLTAGE-GATED POTASSIUM CHANNEL KCND1 voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;metal ion transport#GO:0030001;action potential#GO:0001508 postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;dendritic spine#GO:0043197;cell body#GO:0044297;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cell projection#GO:0042995;neuronal cell body#GO:0043025;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;dendritic tree#GO:0097447;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;voltage-gated potassium channel complex#GO:0008076;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000011373.3|UniProtKB=G3R6W5 G3R6W5 EFCAB9 PTHR47065:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9 molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sexual reproduction#GO:0019953;spermatid development#GO:0007286;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;cilium-dependent cell motility#GO:0060285;anatomical structure development#GO:0048856;anatomical structure maturation#GO:0071695;sperm motility#GO:0097722;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;cell differentiation#GO:0030154;microtubule-based movement#GO:0007018;cell motility#GO:0048870;gamete generation#GO:0007276;spermatogenesis#GO:0007283;developmental process#GO:0032502;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;cell maturation#GO:0048469;cellular developmental process#GO:0048869;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;sperm capacitation#GO:0048240;developmental maturation#GO:0021700;male gamete generation#GO:0048232 cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;sperm principal piece#GO:0097228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;9+2 motile cilium#GO:0097729;cilium#GO:0005929 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000024591.2|UniProtKB=G3RWG9 G3RWG9 HRG PTHR13814:SF3 FETUIN HISTIDINE-RICH GLYCOPROTEIN peptidase inhibitor activity#GO:0030414;binding#GO:0005488;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;ion binding#GO:0043167;endopeptidase regulator activity#GO:0061135;small molecule binding#GO:0036094;peptidase regulator activity#GO:0061134;transition metal ion binding#GO:0046914;cation binding#GO:0043169;zinc ion binding#GO:0008270;enzyme inhibitor activity#GO:0004857;heparin binding#GO:0008201;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;defense response#GO:0006952;immune response#GO:0006955;regulation of hemostasis#GO:1900046;regulation of coagulation#GO:0050818;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of platelet activation#GO:0010543;regulation of immune response#GO:0050776;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;positive regulation of response to external stimulus#GO:0032103;response to biotic stimulus#GO:0009607;regulation of response to wounding#GO:1903034;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;positive regulation of coagulation#GO:0050820;immune system process#GO:0002376;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of blood coagulation#GO:0030193;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of wound healing#GO:0061041 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000013983.3|UniProtKB=G3RDP0 G3RDP0 ARHGEF6 PTHR46026:SF2 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 cell leading edge#GO:0031252;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000006593.3|UniProtKB=A0A2I2YWC4 A0A2I2YWC4 TAPBP PTHR23411:SF22 TAPASIN TAPASIN protein-containing complex binding#GO:0044877;binding#GO:0005488 immune system process#GO:0002376;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;antigen processing and presentation#GO:0019882;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000041332.1|UniProtKB=A0A2I2YB36 A0A2I2YB36 ZNF618 PTHR24383:SF12 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 618 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004289.3|UniProtKB=G3QNT0 G3QNT0 WNT8A PTHR12027:SF92 WNT RELATED PROTEIN WNT-8A signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;system development#GO:0048731;cell fate commitment#GO:0045165;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 GORGO|Ensembl=ENSGGOG00000006835.3|UniProtKB=G3QVC3 G3QVC3 GFER PTHR12645:SF3 ALR/ERV FAD-LINKED SULFHYDRYL OXIDASE ALR catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;disulfide oxidoreductase activity#GO:0015036;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;protein-disulfide reductase activity#GO:0015035 system development#GO:0048731;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;liver development#GO:0001889 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000012614.3|UniProtKB=G3RA54 G3RA54 CENPI PTHR48208:SF2 CENTROMERE PROTEIN I CENTROMERE PROTEIN I protein-containing complex assembly#GO:0065003;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;nuclear division#GO:0000280;kinetochore organization#GO:0051383;organelle fission#GO:0048285;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000025388.2|UniProtKB=G3RR14 G3RR14 PDZRN4 PTHR15545:SF6 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 PDZ DOMAIN-CONTAINING RING FINGER PROTEIN 4 GORGO|Ensembl=ENSGGOG00000027497.2|UniProtKB=G3SFA9 G3SFA9 LOC101132384 PTHR10677:SF21 UBIQUILIN UBIQUILIN-4 polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488;protein binding#GO:0005515 catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009932.3|UniProtKB=G3R375 G3R375 C9H11orf71 PTHR16445:SF0 SIMILAR TO HYPOTHETICAL PROTEIN FLJ20010 SIMILAR TO HUMAN CHROMOSOME 11 OPEN READING FRAME 71 GORGO|Ensembl=ENSGGOG00000036716.1|UniProtKB=A0A2I2Y369 A0A2I2Y369 ADH7 PTHR43880:SF2 ALCOHOL DEHYDROGENASE ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH7 cation binding#GO:0043169;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;zinc ion binding#GO:0008270;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;catabolic process#GO:0009056;response to toxic substance#GO:0009636;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;biological regulation#GO:0065007;aldehyde catabolic process#GO:0046185;hormone metabolic process#GO:0042445;regulation of biological quality#GO:0065008;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of hormone levels#GO:0010817;cellular detoxification of aldehyde#GO:0110095;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000026219.2|UniProtKB=G3RPF4 G3RPF4 GABRA4 PTHR18945:SF393 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-4 signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;neurotransmitter receptor activity#GO:0030594;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;chloride transmembrane transport#GO:1902476;system development#GO:0048731;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;chloride transport#GO:0006821;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;signaling#GO:0023052 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;cell projection membrane#GO:0031253;dendrite#GO:0030425;leading edge membrane#GO:0031256;dendritic tree#GO:0097447 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000004536.3|UniProtKB=G3QPF2 G3QPF2 ERAS PTHR24070:SF369 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE ERAS ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;Ras protein signal transduction#GO:0007265;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000006897.3|UniProtKB=G3QVI5 G3QVI5 GDAP2 PTHR45808:SF6 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 PDGF signaling pathway#P00047>Rho#P01174;VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520 GORGO|Ensembl=ENSGGOG00000013126.3|UniProtKB=A0A2I2Y4U1 A0A2I2Y4U1 HERC1 PTHR45622:SF70 UBIQUITIN-PROTEIN LIGASE E3A-RELATED REGULATOR OF CHROMOSOME CONDENSATION DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005256.3|UniProtKB=G3QRA7 G3QRA7 SFXN5 PTHR11153:SF17 SIDEROFLEXIN SIDEROFLEXIN-5 transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;citrate transmembrane transporter activity#GO:0015137 mitochondrial transport#GO:0006839;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641;tricarboxylic acid transport#GO:0006842;organic acid transport#GO:0015849;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transport#GO:0046942;citrate transport#GO:0015746;intracellular transport#GO:0046907 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000027970.2|UniProtKB=G3RSU6 G3RSU6 PTHR10337:SF2 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 1 enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090 insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to hormone#GO:0009725;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;cellular response to insulin stimulus#GO:0032869;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to nitrogen compound#GO:1901699;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Shc#P00183;CCKR signaling map#P06959>SHC1 @EGFR#P07083;FGF signaling pathway#P00021>Shc#P00639;CCKR signaling map#P06959>p52 SHC1#P07151;Integrin signalling pathway#P00034>Shc#P00949;Ras Pathway#P04393>Shc#P04579;PDGF signaling pathway#P00047>Shc#P01175;CCKR signaling map#P06959>p66 SHC1#P07168;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Shc#P00865;Interleukin signaling pathway#P00036>Shc#P00997;CCKR signaling map#P06959>SHC1#P07138;CCKR signaling map#P06959>p46 SHC1#P07098;EGF receptor signaling pathway#P00018>Shc#P00554 GORGO|Ensembl=ENSGGOG00000016542.3|UniProtKB=G3RK77 G3RK77 CHMP5 PTHR22761:SF85 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 5 late endosome to vacuole transport#GO:0045324;membrane assembly#GO:0071709;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endosomal transport#GO:0016197;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;vesicle budding from membrane#GO:0006900;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;nucleus organization#GO:0006997;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907 nucleus#GO:0005634;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005479.3|UniProtKB=G3QRV3 G3QRV3 ASCL1 PTHR13935:SF66 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of neurogenesis#GO:0050767;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;sensory organ development#GO:0007423;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>MASH1#P06826 GORGO|Ensembl=ENSGGOG00000008379.3|UniProtKB=G3QZB8 G3QZB8 CDH23 PTHR24025:SF18 DESMOGLEIN FAMILY MEMBER CADHERIN-23 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000003055.3|UniProtKB=G3QKM5 G3QKM5 TXNDC17 PTHR12452:SF7 42-9-9 PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to tumor necrosis factor#GO:0034612;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015325.3|UniProtKB=G3RH39 G3RH39 TMEM132E PTHR13388:SF7 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132E cell development#GO:0048468;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;cellular process#GO:0009987;hair cell differentiation#GO:0035315;sensory system development#GO:0048880;nervous system development#GO:0007399;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;developmental process#GO:0032502;neuron differentiation#GO:0030182;sensory organ development#GO:0007423;epidermis development#GO:0008544;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000043384.1|UniProtKB=A0A2I2ZBH7 A0A2I2ZBH7 PTHR10840:SF1 PROGRAMMED CELL DEATH PROTEIN 5 PROGRAMMED CELL DEATH PROTEIN 5 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000037844.1|UniProtKB=A0A2I2Z2S1 A0A2I2Z2S1 PTHR23105:SF186 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000040935.1|UniProtKB=A0A2I2Y824 A0A2I2Y824 LOC101126547 PTHR11736:SF162 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B4 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004269.3|UniProtKB=G3QNR3 G3QNR3 C10H12orf57 PTHR13463:SF3 PROTEIN C10 PROTEIN C10 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;developmental process#GO:0032502;post-embryonic development#GO:0009791 GORGO|Ensembl=ENSGGOG00000016453.3|UniProtKB=G3RJZ8 G3RJZ8 MSANTD1 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009094.3|UniProtKB=G3R135 G3R135 DMRTA1 PTHR12322:SF71 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;sex differentiation#GO:0007548;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000026666.3|UniProtKB=G3SEX9 G3SEX9 ADGRA3 PTHR45930:SF2 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A3 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016429.3|UniProtKB=G3RJY2 G3RJY2 TRIM33 PTHR45915:SF3 TRANSCRIPTION INTERMEDIARY FACTOR E3 UBIQUITIN-PROTEIN LIGASE TRIM33 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription coregulator activity#GO:0003712;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;transcription regulator activity#GO:0140110;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000012641.3|UniProtKB=A0A2I2Z659 A0A2I2Z659 GALNS PTHR42693:SF47 ARYLSULFATASE FAMILY MEMBER N-ACETYLGALACTOSAMINE-6-SULFATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000034957.2|UniProtKB=G3QQL1 G3QQL1 LOC101144201 PTHR11616:SF96 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 GORGO|Ensembl=ENSGGOG00000001678.3|UniProtKB=A0A2K5TIX9 A0A2K5TIX9 SCAND1 PTHR45935:SF10 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000024160.2|UniProtKB=A0A2I2YNT9 A0A2I2YNT9 PTHR13989:SF35 REPLICATION PROTEIN A-RELATED REPLICATION PROTEIN A C-TERMINAL DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle lumen#GO:0043233;replisome#GO:0030894;replication fork#GO:0005657;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013558.4|UniProtKB=G3RCK4 G3RCK4 ITGA3 PTHR23220:SF89 INTEGRIN ALPHA INTEGRIN ALPHA-3 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000003947.3|UniProtKB=A0A2I2Z9X4 A0A2I2Z9X4 MAPK13 PTHR24055:SF107 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 13 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>p38#P00562;TGF-beta signaling pathway#P00052>P38#P01275;B cell activation#P00010>p38#P00384;FGF signaling pathway#P00021>p38#P00644;p38 MAPK pathway#P05918>p38delta#P06020;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Integrin signalling pathway#P00034>ERK#P00907;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Ras Pathway#P04393>p38#P04558;Oxidative stress response#P00046>p38#P01135 GORGO|Ensembl=ENSGGOG00000039989.1|UniProtKB=A0A2I2YXR8 A0A2I2YXR8 ZFP92 PTHR24390:SF167 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 358 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000014205.3|UniProtKB=G3RE86 G3RE86 CASKIN1 PTHR24174:SF11 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 CASKIN-1 cellular process#GO:0009987;regulation of organelle assembly#GO:1902115;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of synapse assembly#GO:0051963;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of postsynapse organization#GO:0099175;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128 cell junction#GO:0030054;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005682.3|UniProtKB=G3QSC9 G3QSC9 SPR PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000003802.3|UniProtKB=A0A2I2YM22 A0A2I2YM22 LOC101137661 PTHR14949:SF25 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 CRYPTIC FAMILY PROTEIN 1B-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;receptor serine/threonine kinase binding#GO:0033612 specification of symmetry#GO:0009799;developmental process#GO:0032502;left/right pattern formation#GO:0060972;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;vasculature development#GO:0001944;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regionalization#GO:0003002;vasculogenesis#GO:0001570;heart development#GO:0007507;determination of bilateral symmetry#GO:0009855;tube development#GO:0035295;animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;determination of left/right symmetry#GO:0007368;cell differentiation#GO:0030154;circulatory system development#GO:0072359 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000026813.2|UniProtKB=G3SEV0 G3SEV0 PTHR23050:SF427 CALCIUM BINDING PROTEIN CALMODULIN-3 calcium ion binding#GO:0005509;ion binding#GO:0043167;kinase activator activity#GO:0019209;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;molecular function activator activity#GO:0140677;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 intracellular signal transduction#GO:0035556;response to calcium ion#GO:0051592;cell communication#GO:0007154;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;detection of chemical stimulus#GO:0009593;regulation of transmembrane transport#GO:0034762;calcineurin-mediated signaling#GO:0097720;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of release of sequestered calcium ion into cytosol#GO:0051279;calcium-mediated signaling#GO:0019722;response to metal ion#GO:0010038;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;regulation of monoatomic ion transport#GO:0043269;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;detection of stimulus#GO:0051606 microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;myelin sheath#GO:0043209;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 GORGO|Ensembl=ENSGGOG00000024286.2|UniProtKB=G3S5K8 G3S5K8 NXPE1 PTHR16165:SF42 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 1 GORGO|Ensembl=ENSGGOG00000009203.3|UniProtKB=G3R1E1 G3R1E1 UNK PTHR14493:SF36 UNKEMPT FAMILY MEMBER RING FINGER PROTEIN UNKEMPT HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell development#GO:0048468;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399 GORGO|Ensembl=ENSGGOG00000007446.3|UniProtKB=G3S9S6 G3S9S6 PTHR23037:SF29 CYTOKINE RECEPTOR INTERLEUKIN-9 RECEPTOR binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;growth factor binding#GO:0019838;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;interleukin-9-mediated signaling pathway#GO:0038113;adaptive immune response#GO:0002250;cytokine-mediated signaling pathway#GO:0019221;immune system process#GO:0002376;cell communication#GO:0007154;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;response to peptide#GO:1901652;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000398.3|UniProtKB=G3QDR6 G3QDR6 TPP1 PTHR14218:SF41 PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2 TRIPEPTIDYL-PEPTIDASE 1 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;protein catabolic process#GO:0030163;protein catabolic process in the vacuole#GO:0007039;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;catabolic process#GO:0009056;central nervous system development#GO:0007417;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;developmental process#GO:0032502;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000009292.3|UniProtKB=G3R1K0 G3R1K0 ZNF382 PTHR24404:SF22 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 382 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000036145.1|UniProtKB=G3SK93 G3SK93 LOC101135184 PTHR23428:SF326 HISTONE H2B HISTONE H2B TYPE 1-J biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;defense response to other organism#GO:0098542;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to external stimulus#GO:0009605;defense response#GO:0006952;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000003797.3|UniProtKB=G3S8G5 G3S8G5 LOC101126415 PTHR23226:SF430 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 1010-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000041812.1|UniProtKB=A0A2I2Z4N3 A0A2I2Z4N3 ZNF10 PTHR24381:SF124 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 10 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000016726.3|UniProtKB=G3S4A8 G3S4A8 RAB34 PTHR47977:SF8 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-34 nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001 vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;lysosome organization#GO:0007040;establishment of protein localization#GO:0045184;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;phagolysosome assembly#GO:0001845;protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;endocytosis#GO:0006897;Golgi to plasma membrane protein transport#GO:0043001;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;membrane organization#GO:0061024;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;phagocytosis#GO:0006909;lytic vacuole organization#GO:0080171;transport#GO:0006810;Golgi to plasma membrane transport#GO:0006893;vesicle fusion#GO:0006906;protein localization to plasma membrane#GO:0072659;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951 Golgi apparatus#GO:0005794;Golgi apparatus subcompartment#GO:0098791;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;Golgi stack#GO:0005795;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000000216.3|UniProtKB=G3QDA4 G3QDA4 ELL2 PTHR23288:SF8 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nucleic acid biosynthetic process#GO:0141187;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;positive regulation of biosynthetic process#GO:0009891;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;biosynthetic process#GO:0009058;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000013038.3|UniProtKB=A0A2I2ZRZ1 A0A2I2ZRZ1 CCNK PTHR10026:SF144 CYCLIN CYCLIN-K kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513 kinase modulator#PC00140;kinase activator#PC00138 Cell cycle#P00013>CdkC#P00489 GORGO|Ensembl=ENSGGOG00000037338.1|UniProtKB=A0A2I2Z346 A0A2I2Z346 PTHR12674:SF7 PREFOLDIN SUBUNIT 5 PREFOLDIN SUBUNIT 5 protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000038871.1|UniProtKB=G3S7R3 G3S7R3 ACP4 PTHR11567:SF145 ACID PHOSPHATASE-RELATED TESTICULAR ACID PHOSPHATASE protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;receptor tyrosine kinase binding#GO:0030971;catalytic activity#GO:0003824 negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of synaptic plasticity#GO:0048167;regulation of neuronal synaptic plasticity#GO:0048168;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological quality#GO:0065008 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000004050.4|UniProtKB=G3QN68 G3QN68 HIPK2 PTHR24058:SF137 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000013778.3|UniProtKB=G3RD42 G3RD42 OCIAD2 PTHR13336:SF2 OVARIAN CARCINOMA IMMUNOREACTIVE ANTIGEN OCIA DOMAIN-CONTAINING PROTEIN 2 organelle membrane#GO:0031090;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000003421.3|UniProtKB=G3SJP0 G3SJP0 UBE4B PTHR13931:SF2 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 B ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;response to stimulus#GO:0050896;catabolic process#GO:0009056 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000003385.3|UniProtKB=G3RWV8 G3RWV8 RGS12 PTHR45945:SF1 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G PROTEIN SIGNALING 12 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 GORGO|Ensembl=ENSGGOG00000015906.3|UniProtKB=A0A2I2ZLT5 A0A2I2ZLT5 TNFSF14 PTHR11471:SF34 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 cell communication#GO:0007154;regulation of apoptotic signaling pathway#GO:2001233;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000021933.2|UniProtKB=G3S6M8 G3S6M8 B3GAT2 PTHR10896:SF8 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 2 catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000009844.3|UniProtKB=G3R305 G3R305 TRA2B PTHR48034:SF1 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG BETA RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000028557.2|UniProtKB=G3SIP2 G3SIP2 CCNDBP1 PTHR15492:SF4 CYCLIN D1-BINDING PROTEIN 1 CYCLIN-D1-BINDING PROTEIN 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007676.3|UniProtKB=G3QXG2 G3QXG2 H1-2 PTHR11467:SF86 HISTONE H1 HISTONE H1.2 chromatin DNA binding#GO:0031490;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004172.3|UniProtKB=A0A2I2Y2A3 A0A2I2Y2A3 PTHR23232:SF178 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN 5-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009052.3|UniProtKB=G3R102 G3R102 LOC101141650 PTHR10707:SF11 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 2, MITOCHONDRIAL mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;oxidoreductase complex#GO:1990204;membrane#GO:0016020;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;transporter complex#GO:1990351;organelle membrane#GO:0031090 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000034837.2|UniProtKB=G3SKJ7 G3SKJ7 COG6 PTHR21506:SF0 COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6 transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;Golgi organization#GO:0007030;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;organelle organization#GO:0006996;retrograde transport, vesicle recycling within Golgi#GO:0000301;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;COG complex#GO:0017119;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000005636.3|UniProtKB=G3QS90 G3QS90 BEST4 PTHR10736:SF55 BESTROPHIN BESTROPHIN-4 monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000044019.1|UniProtKB=A0A2I2YGI0 A0A2I2YGI0 ARL4A PTHR11711:SF139 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4A nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166 vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 GORGO|Ensembl=ENSGGOG00000011408.3|UniProtKB=G3R6Z6 G3R6Z6 JAZF1 PTHR23057:SF0 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004747.3|UniProtKB=G3QPZ9 G3QPZ9 PALD1 PTHR23339:SF96 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PALADIN phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000005627.3|UniProtKB=G3QS84 G3QS84 UBE2Q1 PTHR24068:SF56 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 Q1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005884.3|UniProtKB=G3QSV8 G3QSV8 MACC1 PTHR15603:SF1 SH3 DOMAIN-CONTAINING PROTEIN METASTASIS-ASSOCIATED IN COLON CANCER PROTEIN 1 DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011849.3|UniProtKB=G3S053 G3S053 DGKZ PTHR11255:SF43 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ZETA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;biological regulation#GO:0065007;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;neutral lipid metabolic process#GO:0006638;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165 kinase#PC00137;metabolite interconversion enzyme#PC00262 Gonadotropin-releasing hormone receptor pathway#P06664>DGK-zeta#P06790 GORGO|Ensembl=ENSGGOG00000041361.1|UniProtKB=A0A2I2Z7W5 A0A2I2Z7W5 PTHR23222:SF34 PROHIBITIN PROHIBITIN organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000004316.3|UniProtKB=G3RYM3 G3RYM3 ZNF480 PTHR23226:SF412 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024151.2|UniProtKB=G3RVV1 G3RVV1 PTHR22792:SF71 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 6 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000037747.1|UniProtKB=A0A2I2ZK73 A0A2I2ZK73 SKA2 PTHR32017:SF3 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 spindle#GO:0005819;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;outer kinetochore#GO:0000940;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;microtubule#GO:0005874;spindle microtubule#GO:0005876;kinetochore#GO:0000776;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013695.3|UniProtKB=A0A2I2ZIK0 A0A2I2ZIK0 EIF4B PTHR23236:SF42 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4B RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000003520.3|UniProtKB=G3S0X2 G3S0X2 TMCC2 PTHR17613:SF9 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAINS PROTEIN 2 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013609.3|UniProtKB=G3RCQ6 G3RCQ6 MYH13 PTHR45615:SF44 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-13 microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 multicellular organismal process#GO:0032501;system process#GO:0003008;muscle contraction#GO:0006936;muscle system process#GO:0003012 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000002200.3|UniProtKB=G3QIF6 G3QIF6 FZR1 PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG binding#GO:0005488;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;protein-containing complex binding#GO:0044877;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 primary metabolic process#GO:0044238;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;positive regulation of metabolic process#GO:0009893;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000043870.1|UniProtKB=A0A2I2YTJ6 A0A2I2YTJ6 PTHR46194:SF1 PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED GORGO|Ensembl=ENSGGOG00000009141.3|UniProtKB=G3R183 G3R183 TMEM33 PTHR12703:SF4 TRANSMEMBRANE PROTEIN 33 TRANSMEMBRANE PROTEIN 33 endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endoplasmic reticulum tubular network organization#GO:0071786;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;cellular component organization#GO:0016043;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;endoplasmic reticulum membrane organization#GO:0090158 nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000022939.2|UniProtKB=G3SHM5 G3SHM5 PTHR12832:SF32 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX 11 FAMILY, X-LINKED 2 regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of reproductive process#GO:2000241;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of cell development#GO:0060284;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of cell differentiation#GO:0045595 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;acrosomal vesicle#GO:0001669;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;endomembrane system#GO:0012505;sperm flagellum#GO:0036126 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000007492.3|UniProtKB=G3QX00 G3QX00 TEX36 PTHR35440:SF1 TESTIS-EXPRESSED PROTEIN 36 TESTIS-EXPRESSED PROTEIN 36 GORGO|Ensembl=ENSGGOG00000039277.1|UniProtKB=A0A2I2Z140 A0A2I2Z140 ST6GAL2 PTHR46059:SF3 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 2 sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000015693.3|UniProtKB=G3RI26 G3RI26 ALDH8A1 PTHR43720:SF4 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity#GO:0016491 regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;terpenoid metabolic process#GO:0006721;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;cellular process#GO:0009987;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000008668.3|UniProtKB=G3R000 G3R000 THG1L PTHR12729:SF6 TRNA(HIS) GUANYLYLTRANSFERASE-RELATED TRNA(HIS) GUANYLYLTRANSFERASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 GORGO|Ensembl=ENSGGOG00000009160.3|UniProtKB=G3R1A4 G3R1A4 DPY19L3 PTHR31488:SF4 DPY-19-LIKE 1, LIKE (H. SAPIENS) PROTEIN C-MANNOSYL-TRANSFERASE DPY19L3 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000037038.1|UniProtKB=G3S3F0 G3S3F0 PEX19 PTHR12774:SF2 PEROXISOMAL BIOGENESIS FACTOR 19 PEROXISOMAL BIOGENESIS FACTOR 19 signal sequence receptor activity#GO:0005048 protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;peroxisomal transport#GO:0043574;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;peroxisome organization#GO:0007031;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000023079.2|UniProtKB=G3RUZ2 G3RUZ2 RPS4X PTHR11581:SF35 30S/40S RIBOSOMAL PROTEIN S4 SMALL RIBOSOMAL SUBUNIT PROTEIN ES4, X ISOFORM structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005825.3|UniProtKB=G3QSR1 G3QSR1 LGR6 PTHR24372:SF73 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE RICH REPEAT CONTAINING G PROTEIN-COUPLED RECEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000003596.3|UniProtKB=G3QM07 G3QM07 A3GALT2 PTHR10462:SF59 GLYCOSYLTRANSFERASE-RELATED ALPHA-1,3-GALACTOSYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000007980.3|UniProtKB=G3QY78 G3QY78 NUF2 PTHR21650:SF2 MEMBRALIN/KINETOCHORE PROTEIN NUF2 KINETOCHORE PROTEIN NUF2 binding#GO:0005488;protein-containing complex binding#GO:0044877 sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;organelle organization#GO:0006996;attachment of spindle microtubules to kinetochore#GO:0008608;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic metaphase chromosome alignment#GO:0007080;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;organelle localization#GO:0051640;sexual reproduction#GO:0019953;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;localization#GO:0051179;kinetochore organization#GO:0051383;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;meiotic nuclear division#GO:0140013;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000039811.1|UniProtKB=A0A2I2YQC3 A0A2I2YQC3 PTHR11876:SF34 ALPHA-DEFENSIN 1 RHESUS THETA DEFENSIN-1_3 SUBUNIT A defense response to Gram-positive bacterium#GO:0050830;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000014624.3|UniProtKB=G3RFA1 G3RFA1 PHF11 PTHR12420:SF4 PHD FINGER PROTEIN PHD FINGER PROTEIN 11 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000006381.3|UniProtKB=G3RWW8 G3RWW8 BDH2 PTHR43477:SF4 DIHYDROANTICAPSIN 7-DEHYDROGENASE DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 6 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 biosynthetic process#GO:0009058;siderophore biosynthetic process#GO:0019290;cellular process#GO:0009987;secondary metabolic process#GO:0019748;peptide metabolic process#GO:0006518;secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;siderophore metabolic process#GO:0009237 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000002008.3|UniProtKB=G3QHY7 G3QHY7 PTHR14224:SF98 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 2 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004235.3|UniProtKB=G3RWW1 G3RWW1 POLR1D PTHR13946:SF28 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 GORGO|Ensembl=ENSGGOG00000004363.3|UniProtKB=G3SIQ8 G3SIQ8 USP9X PTHR24006:SF897 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 9X catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cell motility#GO:0048870;cell migration#GO:0016477;cellular process#GO:0009987;regulation of protein stability#GO:0031647 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000012293.3|UniProtKB=G3R9B7 G3R9B7 LOC101146188 PTHR11732:SF197 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B15 catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000003087.3|UniProtKB=G3QKQ6 G3QKQ6 TOP3A PTHR11390:SF21 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-ALPHA catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543 DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;DNA helicase complex#GO:0033202;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000010163.3|UniProtKB=G3SBH5 G3SBH5 MED25 PTHR12433:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008392.3|UniProtKB=A0A2I2ZCZ9 A0A2I2ZCZ9 DCD PTHR40711:SF1 DERMCIDIN-RELATED DERMCIDIN defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;defense response#GO:0006952;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000006884.3|UniProtKB=G3QVG7 G3QVG7 HCN2 PTHR45689:SF11 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 2 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244 regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transporter complex#GO:1990351;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;transmembrane transporter complex#GO:1902495 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000006161.3|UniProtKB=G3QTK0 G3QTK0 GATA3 PTHR10071:SF106 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANS-ACTING T-CELL-SPECIFIC TRANSCRIPTION FACTOR GATA-3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;immune system development#GO:0002520;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of epithelial cell differentiation#GO:0030856;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;embryo development#GO:0009790;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;embryonic organ development#GO:0048568;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000027242.2|UniProtKB=G3S702 G3S702 DYTN PTHR12268:SF18 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROTELIN membrane protein complex#GO:0098796;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000024841.2|UniProtKB=G3RPA0 G3RPA0 PTHR11502:SF15 40S RIBOSOMAL PROTEIN S6 40S RIBOSOMAL PROTEIN S6 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000023361.2|UniProtKB=G3SBL5 G3SBL5 ARX PTHR24329:SF583 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARX sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000008337.3|UniProtKB=G3QZ52 G3QZ52 CCDC186 PTHR18911:SF5 CTCL TUMOR ANTIGEN HD-CL-01 COILED-COIL DOMAIN-CONTAINING PROTEIN 186 GORGO|Ensembl=ENSGGOG00000003004.3|UniProtKB=G3QKI0 G3QKI0 ITFG1 PTHR13412:SF0 T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG T-CELL IMMUNOMODULATORY PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000028291.2|UniProtKB=A0A2I2YB62 A0A2I2YB62 SELENOT PTHR13544:SF0 SELENOPROTEIN T THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036;antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000042788.1|UniProtKB=A0A2I2Z0P2 A0A2I2Z0P2 PPARA PTHR24082:SF197 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;hormone-mediated signaling pathway#GO:0009755;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>PPARalpha/gamma#P06744 GORGO|Ensembl=ENSGGOG00000009807.3|UniProtKB=G3QPR3 G3QPR3 CBX8 PTHR46389:SF1 POLYCOMB GROUP PROTEIN PC CHROMOBOX PROTEIN HOMOLOG 8 chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;PcG protein complex#GO:0031519;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;transferase complex#GO:1990234;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010494.3|UniProtKB=G3R4M8 G3R4M8 LAX1 PTHR24091:SF0 LYMPHOCYTE TRANSMEMBRANE ADAPTER 1 LYMPHOCYTE TRANSMEMBRANE ADAPTER 1 immune response#GO:0006955;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;negative regulation of cell adhesion#GO:0007162;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;negative regulation of cell activation#GO:0050866;cellular response to stimulus#GO:0051716;negative regulation of multicellular organismal process#GO:0051241;leukocyte activation#GO:0045321;negative regulation of leukocyte cell-cell adhesion#GO:1903038;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;negative regulation of T cell activation#GO:0050868;regulation of immune response#GO:0050776;cell activation#GO:0001775;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;antigen receptor-mediated signaling pathway#GO:0050851;lymphocyte activation#GO:0046649;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;regulation of cell activation#GO:0050865;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;response to stimulus#GO:0050896;immune system process#GO:0002376 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015507.3|UniProtKB=G3RHK9 G3RHK9 IFT88 PTHR44117:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 inner ear development#GO:0048839;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;developmental process#GO:0032502;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;sensory organ development#GO:0007423;intracellular transport#GO:0046907;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;organelle assembly#GO:0070925;system development#GO:0048731;non-motile cilium assembly#GO:1905515;localization#GO:0051179;anatomical structure development#GO:0048856;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;renal system development#GO:0072001;cellular component biogenesis#GO:0044085;kidney development#GO:0001822;nervous system development#GO:0007399;cellular component assembly#GO:0022607;neuron differentiation#GO:0030182;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;inner ear receptor cell stereocilium organization#GO:0060122;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;microtubule-based transport#GO:0099111;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cilium organization#GO:0044782;neuron development#GO:0048666;ear development#GO:0043583;cellular localization#GO:0051641 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;intracellular organelle#GO:0043229;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000004475.3|UniProtKB=G3QPA1 G3QPA1 FHIP2B PTHR21705:SF9 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 2B GORGO|Ensembl=ENSGGOG00000039778.1|UniProtKB=A0A2I2ZIL2 A0A2I2ZIL2 PTHR14495:SF2 SHIELDIN COMPLEX SUBUNIT 2 SHIELDIN COMPLEX SUBUNIT 2 regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of response to stress#GO:0080134;regulation of DNA recombination#GO:0000018;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861 GORGO|Ensembl=ENSGGOG00000005910.4|UniProtKB=G3QSY9 G3QSY9 SRBD1 PTHR10724:SF10 30S RIBOSOMAL PROTEIN S1 S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1 mRNA binding#GO:0003729;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001652.3|UniProtKB=G3QH11 G3QH11 ETV5 PTHR11849:SF160 ETS ETS TRANSLOCATION VARIANT 5 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004106.3|UniProtKB=G3QNB8 G3QNB8 CELF1 PTHR24012:SF686 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 1 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 regulation of mRNA splicing, via spliceosome#GO:0048024;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004112.3|UniProtKB=G3QNC0 G3QNC0 PTHR24235:SF16 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 6-RELATED G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009249.3|UniProtKB=G3R1G7 G3R1G7 B3GNT3 PTHR11214:SF405 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;aminoglycan biosynthetic process#GO:0006023;biosynthetic process#GO:0009058 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000006574.3|UniProtKB=G3SIM3 G3SIM3 NAV3 PTHR12784:SF18 STEERIN NEURON NAVIGATOR 3 anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752 GORGO|Ensembl=ENSGGOG00000010544.3|UniProtKB=G3R4S3 G3R4S3 KANK2 PTHR24168:SF0 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;negative regulation of RNA metabolic process#GO:0051253;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;negative regulation of actin filament polymerization#GO:0030837;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of actin filament length#GO:0030832;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;negative regulation of cell population proliferation#GO:0008285;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of cell cycle G1/S phase transition#GO:1902806;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;regulation of cell population proliferation#GO:0042127;regulation of RNA metabolic process#GO:0051252;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of protein polymerization#GO:0032272;regulation of actin cytoskeleton organization#GO:0032956;regulation of cell cycle process#GO:0010564;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cell cycle#GO:0045786;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of DNA-templated transcription#GO:0045892;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;regulation of intracellular signal transduction#GO:1902531;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;regulation of macromolecule biosynthetic process#GO:0010556;regulation of actin filament organization#GO:0110053;regulation of mitotic cell cycle#GO:0007346;regulation of gene expression#GO:0010468;regulation of actin filament-based process#GO:0032970;negative regulation of cell cycle process#GO:0010948;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of DNA-templated transcription#GO:0006355;negative regulation of cytoskeleton organization#GO:0051494 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000025982.2|UniProtKB=G3S6K9 G3S6K9 PTHR15341:SF3 SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000039586.1|UniProtKB=A0A2I2YQX5 A0A2I2YQX5 PTHR13313:SF1 CYTOCHROME C OXIDASE SUBUNIT VIIC CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;generation of precursor metabolites and energy#GO:0006091;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transporter complex#GO:1990351 oxidoreductase#PC00176;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000000415.3|UniProtKB=A0A2I2Z909 A0A2I2Z909 CUL4A PTHR11932:SF68 CULLIN CULLIN-4A ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;ribosome biogenesis#GO:0042254;protein modification by small protein conjugation or removal#GO:0070647;ribonucleoprotein complex biogenesis#GO:0022613;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000047.3|UniProtKB=A0A2I2ZVI0 A0A2I2ZVI0 FCN3 PTHR19143:SF444 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-3 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000006239.3|UniProtKB=G3QTS2 G3QTS2 CFAP210 PTHR28663:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 173 CILIA- AND FLAGELLA- ASSOCIATED PROTEIN 210 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;intracellular organelle#GO:0043229;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881 GORGO|Ensembl=ENSGGOG00000009922.3|UniProtKB=G3R372 G3R372 CFAP100 PTHR21683:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 100 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000015135.3|UniProtKB=G3RGL9 G3RGL9 HECA PTHR13425:SF3 HEADCASE PROTEIN HEADCASE PROTEIN HOMOLOG GORGO|Ensembl=ENSGGOG00000015019.3|UniProtKB=G3RGB9 G3RGB9 NCAPG PTHR14418:SF5 CONDENSIN COMPLEX SUBUNIT 3-RELATED CONDENSIN COMPLEX SUBUNIT 3 chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;nuclear division#GO:0000280;organelle fission#GO:0048285;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;condensin complex#GO:0000796;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000016146.3|UniProtKB=G3RJ69 G3RJ69 PTHR45880:SF3 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 GORGO|Ensembl=ENSGGOG00000034872.2|UniProtKB=G3SKR0 G3SKR0 UTS2B PTHR36876:SF1 UROTENSIN-2B UROTENSIN-2B protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of blood pressure#GO:0008217;circulatory system process#GO:0003013;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;system process#GO:0003008;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 GORGO|Ensembl=ENSGGOG00000005762.3|UniProtKB=G3SDE4 G3SDE4 SLC7A11 PTHR11785:SF323 AMINO ACID TRANSPORTER CYSTINE_GLUTAMATE TRANSPORTER antiporter activity#GO:0015297;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;carboxylic acid transmembrane transporter activity#GO:0046943 localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010914.3|UniProtKB=G3R5S1 G3R5S1 ADAMTSL1 PTHR13723:SF157 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000001173.3|UniProtKB=A0A2I2Z3M5 A0A2I2Z3M5 PTHR11461:SF129 SERINE PROTEASE INHIBITOR, SERPIN SERPIN E3 enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000011240.3|UniProtKB=G3R6K2 G3R6K2 STRA6 PTHR21444:SF16 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 RECEPTOR FOR RETINOL UPTAKE STRA6 transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000000635.3|UniProtKB=G3QED3 G3QED3 KIF20B PTHR24115:SF534 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF20B protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000015515.3|UniProtKB=G3RHL6 G3RHL6 ARMC12 PTHR47144:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 12 ARMADILLO REPEAT-CONTAINING PROTEIN 12 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000012746.4|UniProtKB=G3RAG3 G3RAG3 CCDC152 PTHR35253:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 152 COILED-COIL DOMAIN-CONTAINING PROTEIN 152 GORGO|Ensembl=ENSGGOG00000008547.4|UniProtKB=A0A2I2ZBY5 A0A2I2ZBY5 CSTPP1 PTHR34252:SF1 UPF0705 PROTEIN C11ORF49 CENTRIOLAR SATELLITE-ASSOCIATED TUBULIN POLYGLUTAMYLASE COMPLEX REGULATOR 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 GORGO|Ensembl=ENSGGOG00000014664.3|UniProtKB=G3RFE4 G3RFE4 BLTP3A PTHR22774:SF15 CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 3A lipid transfer activity#GO:0120013;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 localization#GO:0051179;cellular localization#GO:0051641;lipid localization#GO:0010876;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000016054.3|UniProtKB=G3RIZ5 G3RIZ5 REC8 PTHR12585:SF27 SCC1 / RAD21 FAMILY MEMBER MEIOTIC RECOMBINATION PROTEIN REC8 HOMOLOG binding#GO:0005488;chromatin binding#GO:0003682 cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;sister chromatid cohesion#GO:0007062;organelle organization#GO:0006996;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276;double-strand break repair#GO:0006302 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000039424.1|UniProtKB=A0A2I2Y6U7 A0A2I2Y6U7 PTHR12138:SF135 PRIMATE-EXPANDED PROTEIN FAMILY SECRETED PROTEIN GORGO|Ensembl=ENSGGOG00000011316.3|UniProtKB=G3SB56 G3SB56 ALDH1L2 PTHR11699:SF131 ALDEHYDE DEHYDROGENASE-RELATED MITOCHONDRIAL 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000005526.3|UniProtKB=A0A2I2ZXN2 A0A2I2ZXN2 GGT5 PTHR11686:SF19 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 5 PROENZYME catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;inflammatory response#GO:0006954;glutathione metabolic process#GO:0006749;oxoacid metabolic process#GO:0043436;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;icosanoid metabolic process#GO:0006690;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;response to stress#GO:0006950;sulfur compound metabolic process#GO:0006790;defense response#GO:0006952;sulfur compound catabolic process#GO:0044273;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000013596.3|UniProtKB=G3RCN2 G3RCN2 KRR1 PTHR12581:SF0 HIV-1 REV BINDING PROTEIN 2, 3 KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000037809.1|UniProtKB=A0A2I2ZT81 A0A2I2ZT81 MCCC2 PTHR22855:SF13 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002731.3|UniProtKB=A0A2I2ZCT2 A0A2I2ZCT2 MOV10 PTHR45418:SF7 CANCER/TESTIS ANTIGEN 55 RNA HELICASE GORGO|Ensembl=ENSGGOG00000005006.3|UniProtKB=G3QQN6 G3QQN6 TPST2 PTHR12788:SF6 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE 2 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000027774.2|UniProtKB=G3S5S8 G3S5S8 SUV39H1 PTHR46223:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H1 histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000022249.2|UniProtKB=G3SGZ8 G3SGZ8 ATRNL1 PTHR24044:SF487 NOTCH LIGAND FAMILY MEMBER ATTRACTIN-LIKE PROTEIN 1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000026840.2|UniProtKB=A0A2I2ZIG5 A0A2I2ZIG5 PLEK PTHR12092:SF1 PLECKSTRIN PLECKSTRIN actin filament-based process#GO:0030029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000003336.3|UniProtKB=A0A2I2YQW3 A0A2I2YQW3 LRRK2 PTHR48005:SF13 LEUCINE RICH REPEAT KINASE 2 SERINE_THREONINE-PROTEIN KINASE DDB_G0278509-RELATED protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 GORGO|Ensembl=ENSGGOG00000006256.3|UniProtKB=G3QTT6 G3QTT6 CCDC51 PTHR28624:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 51 MITOCHONDRIAL POTASSIUM CHANNEL GORGO|Ensembl=ENSGGOG00000002650.3|UniProtKB=G3RSJ8 G3RSJ8 SLC37A4 PTHR43826:SF3 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;phosphate transmembrane transporter activity#GO:0005315 organophosphate ester transport#GO:0015748;phosphate ion transport#GO:0006817;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;transport#GO:0006810 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000010152.3|UniProtKB=G3R3S5 G3R3S5 ZNF408 PTHR24377:SF964 IP01015P-RELATED ZINC FINGER PROTEIN 408 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006806.3|UniProtKB=G3RZF5 G3RZF5 SEC24B PTHR13803:SF42 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24B cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;zinc ion binding#GO:0008270;SNARE binding#GO:0000149 COPII-coated vesicle budding#GO:0090114;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated membrane#GO:0048475;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000009063.3|UniProtKB=G3R113 G3R113 CHCHD10 PTHR13523:SF4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 10, MITOCHONDRIAL mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 nucleus#GO:0005634;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007120.3|UniProtKB=G3QW26 G3QW26 HEG1 PTHR24037:SF3 HEART DEVELOPMENT PROTEIN WITH EGF-LIKE DOMAINS 1 PROTEIN HEG HOMOLOG 1 multicellular organismal process#GO:0032501;heart development#GO:0007507;circulatory system development#GO:0072359;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275 GORGO|Ensembl=ENSGGOG00000009987.3|UniProtKB=G3R3C6 G3R3C6 SCHIP1 PTHR13103:SF2 SCHWANNOMIN INTERACTING PROTEIN 1 IQCJ-SCHIP1 READTHROUGH TRANSCRIPT PROTEIN-RELATED biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000006808.4|UniProtKB=G3QVA7 G3QVA7 ITGBL1 PTHR10082:SF3 INTEGRIN BETA SUBUNIT INTEGRIN BETA-LIKE PROTEIN 1 cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515 cell adhesion mediated by integrin#GO:0033627;cell surface receptor signaling pathway#GO:0007166;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;cell migration#GO:0016477;biological regulation#GO:0065007;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052 signaling receptor complex#GO:0043235;anchoring junction#GO:0070161;cell junction#GO:0030054;integrin complex#GO:0008305;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 GORGO|Ensembl=ENSGGOG00000006264.3|UniProtKB=G3QTU9 G3QTU9 ATRIP PTHR28594:SF1 ATR-INTERACTING PROTEIN ATR-INTERACTING PROTEIN DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 GORGO|Ensembl=ENSGGOG00000017159.3|UniProtKB=A0A2I2Z7Z4 A0A2I2Z7Z4 PIK3C2G PTHR10048:SF29 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT GAMMA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;organophosphate metabolic process#GO:0019637;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;cell motility#GO:0048870;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phosphatidylinositol phosphate biosynthetic process#GO:0046854;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 kinase#PC00137 T cell activation#P00053>PI3K#P01322;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;p53 pathway feedback loops 2#P04398>PI3K#P04661;FGF signaling pathway#P00021>PI3K#P00640;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;EGF receptor signaling pathway#P00018>PI3K#P00557;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823 GORGO|Ensembl=ENSGGOG00000013459.3|UniProtKB=G3RCA1 G3RCA1 C1H1orf174 PTHR28491:SF1 UPF0688 PROTEIN C1ORF174 UPF0688 PROTEIN C1ORF174 GORGO|Ensembl=ENSGGOG00000004238.3|UniProtKB=G3QNP1 G3QNP1 TBX3 PTHR11267:SF91 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 GORGO|Ensembl=ENSGGOG00000007156.3|UniProtKB=G3SA86 G3SA86 ADAR PTHR10910:SF107 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN DOUBLE-STRANDED RNA-SPECIFIC ADENOSINE DEAMINASE catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;RNA binding#GO:0003723;hydrolase activity#GO:0016787;tRNA-specific adenosine deaminase activity#GO:0008251;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 adenosine to inosine editing#GO:0006382;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;base conversion or substitution editing#GO:0016553;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000028049.2|UniProtKB=G3SE69 G3SE69 RNF114 PTHR46016:SF3 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF114 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 GORGO|Ensembl=ENSGGOG00000042691.1|UniProtKB=A0A2I2YG55 A0A2I2YG55 PTHR12868:SF2 NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012716.3|UniProtKB=G3RAD2 G3RAD2 CORO1A PTHR10856:SF18 CORONIN CORONIN-1A binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;cell migration#GO:0016477;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular polymer#GO:0099081;lamellipodium#GO:0030027;supramolecular complex#GO:0099080;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000022608.2|UniProtKB=G3RSR7 G3RSR7 TRIP4 PTHR12963:SF6 THYROID RECEPTOR INTERACTING PROTEIN RELATED ACTIVATING SIGNAL COINTEGRATOR 1 protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;modification-dependent macromolecule catabolic process#GO:0043632;translation#GO:0006412;protein catabolic process#GO:0030163;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;catabolic process#GO:0009056;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;rescue of stalled cytosolic ribosome#GO:0072344;modification-dependent protein catabolic process#GO:0019941;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;translational elongation#GO:0006414;metabolic process#GO:0008152;gene expression#GO:0010467;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000039775.1|UniProtKB=A0A2I2Z2X2 A0A2I2Z2X2 PTHR42679:SF5 S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000010111.3|UniProtKB=A0A2I2YA54 A0A2I2YA54 SYT11 PTHR10024:SF115 SYNAPTOTAGMIN SYNAPTOTAGMIN-11 binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149;protein binding#GO:0005515;molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772 regulation of cellular component organization#GO:0051128;signaling#GO:0023052;export from cell#GO:0140352;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;positive regulation of cellular component organization#GO:0051130;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of transport#GO:0051050;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;synaptic vesicle exocytosis#GO:0016079;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulated exocytosis#GO:0045055;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;regulation of exocytosis#GO:0017157;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;membrane fusion#GO:0061025;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504 intracellular organelle#GO:0043229;axon#GO:0030424;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;secretory vesicle#GO:0099503;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 GORGO|Ensembl=ENSGGOG00000039201.1|UniProtKB=A0A2I2ZPL9 A0A2I2ZPL9 PTHR22850:SF203 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP4-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;histone deacetylase complex#GO:0000118;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000002709.3|UniProtKB=G3QJR4 G3QJR4 ZNRF4 PTHR22765:SF347 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ZNRF4 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cellular process#GO:0009987;biological regulation#GO:0065007;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012253.3|UniProtKB=G3R975 G3R975 OLFM4 PTHR23192:SF7 OLFACTOMEDIN-RELATED OLFACTOMEDIN-4 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000012807.3|UniProtKB=G3RAL7 G3RAL7 KRT16 PTHR23239:SF105 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 16 structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;epidermis development#GO:0008544;developmental process#GO:0032502;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;skin development#GO:0043588;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000016571.3|UniProtKB=G3RKA2 G3RKA2 MIP PTHR19139:SF39 AQUAPORIN TRANSPORTER LENS FIBER MAJOR INTRINSIC PROTEIN water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 fluid transport#GO:0042044;establishment of localization#GO:0051234;localization#GO:0051179;water transport#GO:0006833;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003857.3|UniProtKB=A0A2I2YB38 A0A2I2YB38 LOC101126460 PTHR26451:SF28 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10J3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000027317.2|UniProtKB=G3SJC1 G3SJC1 IDO1 PTHR28657:SF2 INDOLEAMINE 2,3-DIOXYGENASE INDOLEAMINE 2,3-DIOXYGENASE 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;indole-containing compound metabolic process#GO:0042430;purine nucleotide metabolic process#GO:0006163;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000000505.3|UniProtKB=G3RU67 G3RU67 LOC101127319 PTHR22800:SF258 C-TYPE LECTIN PROTEINS NKG2-A_NKG2-B TYPE II INTEGRAL MEMBRANE PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of leukocyte mediated immunity#GO:0002703;negative regulation of defense response#GO:0031348;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;response to external stimulus#GO:0009605;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;response to other organism#GO:0051707;leukocyte mediated immunity#GO:0002443;natural killer cell mediated immunity#GO:0002228;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;positive regulation of response to external stimulus#GO:0032103;response to stress#GO:0006950;negative regulation of innate immune response#GO:0045824;negative regulation of response to external stimulus#GO:0032102;regulation of defense response#GO:0031347;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of natural killer cell mediated immunity#GO:0002715;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of natural killer cell mediated immunity#GO:0002717;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cell killing#GO:0031341;lymphocyte mediated immunity#GO:0002449;negative regulation of biological process#GO:0048519;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000026214.2|UniProtKB=A0A2I2YYE6 A0A2I2YYE6 UFM1 PTHR15825:SF5 UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-FOLD MODIFIER 1 response to stimulus#GO:0050896;catabolic process#GO:0009056;macroautophagy#GO:0016236;reticulophagy#GO:0061709;response to stress#GO:0006950;autophagy#GO:0006914;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;process utilizing autophagic mechanism#GO:0061919;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000013290.3|UniProtKB=A0A2I2ZT15 A0A2I2ZT15 SYTL3 PTHR45716:SF1 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 3 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;exocytosis#GO:0006887 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 GORGO|Ensembl=ENSGGOG00000041376.1|UniProtKB=A0A2I2Z8I4 A0A2I2Z8I4 PTHR43477:SF4 DIHYDROANTICAPSIN 7-DEHYDROGENASE DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 6 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 siderophore metabolic process#GO:0009237;secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;secondary metabolic process#GO:0019748;peptide metabolic process#GO:0006518;cellular process#GO:0009987;siderophore biosynthetic process#GO:0019290;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005962.3|UniProtKB=A0A2I2YIG0 A0A2I2YIG0 CACYBP PTHR13164:SF3 CALICYLIN BINDING PROTEIN CALCYCLIN-BINDING PROTEIN ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;heart development#GO:0007507;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000013415.3|UniProtKB=G3RMD0 G3RMD0 PCIF1 PTHR21727:SF0 PHOSPHORYLATED CTD INTERACTING FACTOR 1 MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000003076.3|UniProtKB=A0A2I2Y3R6 A0A2I2Y3R6 LAYN PTHR14789:SF2 CHONDROLECTIN VARIANT CHODLFDELTAE. LAYILIN ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;organic acid binding#GO:0043177 GORGO|Ensembl=ENSGGOG00000004178.3|UniProtKB=G3QNI2 G3QNI2 PPP1R42 PTHR45973:SF30 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 42 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000000323.3|UniProtKB=G3RQA7 G3RQA7 DARS2 PTHR22594:SF56 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000007283.3|UniProtKB=G3QWG9 G3QWG9 TMEM164 PTHR20948:SF5 TRANSMEMBRANE PROTEIN 164 TRANSMEMBRANE PROTEIN 164 regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068 GORGO|Ensembl=ENSGGOG00000000230.3|UniProtKB=G3QDB7 G3QDB7 GPC4 PTHR10822:SF25 GLYPICAN GLYPICAN-4 regulation of protein localization#GO:0032880;synaptic membrane adhesion#GO:0099560;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;synapse organization#GO:0050808;cell adhesion#GO:0007155;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;regulation of synapse assembly#GO:0051963;cell migration#GO:0016477;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010112.3|UniProtKB=G3R3P0 G3R3P0 TBC1D21 PTHR22957:SF489 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 21 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000010261.3|UniProtKB=G3R428 G3R428 PPP2R1B PTHR10648:SF9 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 65 KDA REGULATORY SUBUNIT A BETA ISOFORM protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;microtubule cytoskeleton organization#GO:0000226;sister chromatid cohesion#GO:0007062;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;meiotic sister chromatid cohesion#GO:0051177;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 GORGO|Ensembl=ENSGGOG00000025366.2|UniProtKB=G3SJW6 G3SJW6 CLDN16 PTHR12002:SF56 CLAUDIN CLAUDIN-16 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;paracellular transport#GO:0160184;establishment of localization#GO:0051234;cell-cell junction organization#GO:0045216;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000036732.1|UniProtKB=A0A2I2Y634 A0A2I2Y634 PTHR10933:SF13 IMMUNOGLOBULIN-BINDING PROTEIN 1 IGBP1 protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;signaling#GO:0023052;TOR signaling#GO:0031929;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000014544.3|UniProtKB=G3RT38 G3RT38 PTHR11905:SF20 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 8 metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;cell adhesion molecule binding#GO:0050839;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;metallopeptidase activity#GO:0008237;binding#GO:0005488 regulation of cell migration#GO:0030334;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;positive regulation of locomotion#GO:0040017;defense response#GO:0006952;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;inflammatory response#GO:0006954;regulation of cell motility#GO:2000145;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of leukocyte migration#GO:0002685;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;positive regulation of immune system process#GO:0002684;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;proteolysis#GO:0006508;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;response to stimulus#GO:0050896 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000002621.3|UniProtKB=G3QJI6 G3QJI6 HJURP PTHR15992:SF5 HOLLIDAY JUNCTION RECOGNITION PROTEIN HOLLIDAY JUNCTION RECOGNITION PROTEIN protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;kinetochore organization#GO:0051383;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000004542.3|UniProtKB=G3QPG7 G3QPG7 PER2 PTHR11269:SF9 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription factor binding#GO:0008134;protein binding#GO:0005515;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976 negative regulation of DNA-templated transcription#GO:0045892;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;rhythmic process#GO:0048511;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;negative regulation of cellular process#GO:0048523;photoperiodism#GO:0009648;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to radiation#GO:0009314;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transcription cofactor#PC00217 Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>per#G01499;Circadian clock system#P00015>Per#P00504 GORGO|Ensembl=ENSGGOG00000009863.3|UniProtKB=G3R324 G3R324 RTN2 PTHR45799:SF3 RETICULON-LIKE PROTEIN RETICULON-2 organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;endoplasmic reticulum tubular network organization#GO:0071786;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endoplasmic reticulum membrane organization#GO:0090158;cellular component organization or biogenesis#GO:0071840 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000002606.3|UniProtKB=G3QJI1 G3QJI1 MROH2A PTHR23120:SF14 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 2A cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000000293.3|UniProtKB=G3S1M5 G3S1M5 PTHR24035:SF127 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 11 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;endocytosis#GO:0006897;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;localization#GO:0051179;cellular process#GO:0009987;membrane organization#GO:0061024;phagocytosis#GO:0006909;transport#GO:0006810;substrate adhesion-dependent cell spreading#GO:0034446;membrane invagination#GO:0010324;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000016969.3|UniProtKB=G3RLC0 G3RLC0 GPAM PTHR12563:SF16 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;triglyceride biosynthetic process#GO:0019432;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000023948.2|UniProtKB=A0A2I2ZPC0 A0A2I2ZPC0 ENSA PTHR10358:SF21 ENDOSULFINE ALPHA-ENDOSULFINE molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000015898.3|UniProtKB=A0A2I2YHN2 A0A2I2YHN2 SNU13 PTHR23105:SF38 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER NHP2-LIKE PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;intracellular membraneless organelle#GO:0043232;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;precatalytic spliceosome#GO:0071011;nucleolus#GO:0005730;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;small-subunit processome#GO:0032040;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000022838.2|UniProtKB=G3RY76 G3RY76 CAPSL PTHR34524:SF5 CALCYPHOSIN CALCYPHOSIN-LIKE PROTEIN calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000016560.3|UniProtKB=G3RK98 G3RK98 ATP5F1A PTHR48082:SF3 ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT ALPHA, MITOCHONDRIAL proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;purine ribonucleotide binding#GO:0032555;transporter activity#GO:0005215;ligase activity#GO:0016874;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;proton transmembrane transporter activity#GO:0015078;purine nucleotide binding#GO:0017076;channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824 ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ATP biosynthetic process#GO:0006754;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 ATP synthesis#P02721>F1 alpha#P02791 GORGO|Ensembl=ENSGGOG00000025843.2|UniProtKB=A0A2I2YCG4 A0A2I2YCG4 PTHR31553:SF4 NF-KAPPA-B ESSENTIAL MODULATOR CCHC NOA-TYPE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;protein binding#GO:0005515 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000006153.3|UniProtKB=G3S6E4 G3S6E4 CLGN PTHR11073:SF7 CALRETICULIN AND CALNEXIN CALMEGIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 protein maturation#GO:0051604;gene expression#GO:0010467;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000015429.3|UniProtKB=G3RHE4 G3RHE4 CEP95 PTHR22545:SF0 CENTROSOMAL PROTEIN OF 95 KDA CENTROSOMAL PROTEIN OF 95 KDA microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000004315.3|UniProtKB=G3QNV8 G3QNV8 MAP4 PTHR11501:SF16 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 4 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cell development#GO:0048468;regulation of microtubule-based movement#GO:0060632;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;generation of neurons#GO:0048699;regulation of microtubule-based process#GO:0032886;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;axon#GO:0030424;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000008416.3|UniProtKB=G3QZB3 G3QZB3 KCNA10 PTHR11537:SF44 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 10 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;metal ion transport#GO:0030001;action potential#GO:0001508;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000000624.3|UniProtKB=G3SBH1 G3SBH1 HEPHL1 PTHR11709:SF233 MULTI-COPPER OXIDASE FERROXIDASE HEPHL1 catalytic activity#GO:0003824;oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000004488.3|UniProtKB=A0A2I2YGP2 A0A2I2YGP2 ZDHHC15 PTHR22883:SF270 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC15 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 developmental maturation#GO:0021700;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;developmental process#GO:0032502;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000038008.1|UniProtKB=A0A2I2ZAA8 A0A2I2ZAA8 PTHR11885:SF17 RIBOSOMAL PROTEIN S15P/S13E SMALL RIBOSOMAL SUBUNIT PROTEIN US15 N-TERMINAL DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;cytosolic ribosome#GO:0022626;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000001673.3|UniProtKB=G3SJM4 G3SJM4 GOLGA5 PTHR13815:SF7 GOLGIN-84 GOLGIN SUBFAMILY A MEMBER 5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle organization#GO:0006996;retrograde transport, vesicle recycling within Golgi#GO:0000301;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi stack#GO:0005795;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000028083.2|UniProtKB=G3RZ97 G3RZ97 TOP2B PTHR10169:SF36 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2-BETA ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097 nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;cellular process#GO:0009987;resolution of meiotic recombination intermediates#GO:0000712;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;reproductive process#GO:0022414;homologous recombination#GO:0035825;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 GORGO|Ensembl=ENSGGOG00000010765.3|UniProtKB=G3R5C4 G3R5C4 PTHR33955:SF2 TRANSMEMBRANE PROTEIN 52 TRANSMEMBRANE PROTEIN 52 GORGO|Ensembl=ENSGGOG00000026167.2|UniProtKB=G3SDB8 G3SDB8 PTHR10383:SF15 SERINE INCORPORATOR SERINE INCORPORATOR 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000027575.2|UniProtKB=G3RWS2 G3RWS2 AAR2 PTHR12689:SF4 A1 CISTRON SPLICING FACTOR AAR2-RELATED PROTEIN AAR2 HOMOLOG cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000016034.4|UniProtKB=G3RIX5 G3RIX5 TXNDC16 PTHR22699:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000027236.2|UniProtKB=G3RZW4 G3RZW4 PTHR16222:SF23 ADP-RIBOSYLGLYCOHYDROLASE INACTIVE ADP-RIBOSYLTRANSFERASE ARH2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000023323.2|UniProtKB=G3RWD3 G3RWD3 SPCS3 PTHR12804:SF0 MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23 SIGNAL PEPTIDASE COMPLEX SUBUNIT 3 primary metabolic process#GO:0044238;protein targeting#GO:0006605;localization#GO:0051179;protein metabolic process#GO:0019538;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234 endoplasmic reticulum membrane#GO:0005789;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 GORGO|Ensembl=ENSGGOG00000006520.3|UniProtKB=A0A2I2YYU6 A0A2I2YYU6 FBXO9 PTHR12874:SF29 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 9 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000022638.2|UniProtKB=G3RTA8 G3RTA8 MYNN PTHR24377:SF1049 IP01015P-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004071.3|UniProtKB=A0A2I2YJF6 A0A2I2YJF6 GSPT1 PTHR23115:SF125 TRANSLATION FACTOR EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR GTP-BINDING SUBUNIT ERF3A ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 translational termination#GO:0006415;translation#GO:0006412;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000004974.3|UniProtKB=G3SI36 G3SI36 LOC101133420 PTHR11346:SF15 GALECTIN PLACENTAL PROTEIN 13-LIKE binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000009068.3|UniProtKB=G3R115 G3R115 PTHR11653:SF4 PARVALBUMIN ALPHA ONCOMODULIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000009548.3|UniProtKB=A0A2I2ZP75 A0A2I2ZP75 ANKRD28 PTHR24123:SF75 ANKYRIN REPEAT-CONTAINING SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT A enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cellular process#GO:0050794;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell adhesion#GO:0030155;regulation of cellular component organization#GO:0051128;regulation of cell junction assembly#GO:1901888;positive regulation of cellular component organization#GO:0051130;regulation of cell-matrix adhesion#GO:0001952 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000038723.1|UniProtKB=A0A2I2Y8U9 A0A2I2Y8U9 MB21D2 PTHR10656:SF47 CELL FATE DETERMINING PROTEIN MAB21-RELATED NUCLEOTIDYLTRANSFERASE MB21D2 nucleotidyltransferase#PC00174;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000014486.3|UniProtKB=G3REZ2 G3REZ2 STKLD1 PTHR24363:SF5 SERINE/THREONINE PROTEIN KINASE SERINE_THREONINE KINASE-LIKE DOMAIN-CONTAINING PROTEIN STKLD1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000009948.3|UniProtKB=G3RVZ1 G3RVZ1 OR8U1 PTHR48018:SF91 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012359.3|UniProtKB=G3R9I5 G3R9I5 SSRP1 PTHR45849:SF7 FACT COMPLEX SUBUNIT SSRP1 FACT COMPLEX SUBUNIT SSRP1 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of chromatin organization#GO:1902275;regulation of biological process#GO:0050789 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000025853.2|UniProtKB=G3RV49 G3RV49 CBX3 PTHR22812:SF134 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 3 chromatin binding#GO:0003682;binding#GO:0005488 cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular component assembly#GO:0022607;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000011285.3|UniProtKB=A0A2I2Z0S9 A0A2I2Z0S9 IL15 PTHR14356:SF3 INTERLEUKIN-15-RELATED INTERLEUKIN-15 signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;positive regulation of leukocyte activation#GO:0002696;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of T cell activation#GO:0050870;myeloid leukocyte activation#GO:0002274;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;positive regulation of T cell proliferation#GO:0042102;regulation of lymphocyte activation#GO:0051249;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;positive regulation of leukocyte proliferation#GO:0070665;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;positive regulation of lymphocyte proliferation#GO:0050671;regulation of immune response#GO:0050776;cell activation#GO:0001775;regulation of T cell proliferation#GO:0042129;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;leukocyte activation#GO:0045321;positive regulation of cell adhesion#GO:0045785 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;cytokine#PC00083;interleukin superfamily#PC00128 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870;Interleukin signaling pathway#P00036>Interleukin#P00970 GORGO|Ensembl=ENSGGOG00000014986.3|UniProtKB=A0A2I2YD04 A0A2I2YD04 PPP2R5A PTHR10257:SF6 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT ALPHA ISOFORM enzyme activator activity#GO:0008047;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle process#GO:0022402;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;EGF receptor signaling pathway#P00018>PP2A#P00547 GORGO|Ensembl=ENSGGOG00000043516.1|UniProtKB=A0A2I2Z0Y7 A0A2I2Z0Y7 PTHR48112:SF21 HIGH MOBILITY GROUP PROTEIN DSP1 HMG BOX DOMAIN-CONTAINING PROTEIN cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000011800.3|UniProtKB=G3RXB5 G3RXB5 NLGN2 PTHR43903:SF3 NEUROLIGIN NEUROLIGIN-2 cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;organelle#GO:0043226;postsynaptic specialization#GO:0099572;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cell junction#GO:0030054 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000005807.3|UniProtKB=G3QSP4 G3QSP4 GJA9 PTHR11984:SF60 CONNEXIN GAP JUNCTION ALPHA-9 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987 cell junction#GO:0030054;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 gap junction#PC00105;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000024518.2|UniProtKB=A0A2I2Z5M1 A0A2I2Z5M1 NFATC2 PTHR12533:SF4 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;calcium-mediated signaling#GO:0019722;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264;immunoglobulin fold transcription factor#PC00251 Axon guidance mediated by netrin#P00009>NFAT#P00359;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367;Wnt signaling pathway#P00057>NFAT#P01452;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;CCKR signaling map#P06959>NFAT1#P07176 GORGO|Ensembl=ENSGGOG00000006163.3|UniProtKB=G3SCN7 G3SCN7 MIDEAS PTHR16089:SF24 REST COREPRESSOR COREST PROTEIN-RELATED MITOTIC DEACETYLASE-ASSOCIATED SANT DOMAIN PROTEIN transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000563.3|UniProtKB=G3QE66 G3QE66 MSL2 PTHR16048:SF3 MSL2-RELATED E3 UBIQUITIN-PROTEIN LIGASE MSL2 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000041032.1|UniProtKB=A0A2I2ZTX2 A0A2I2ZTX2 MPLKIP PTHR22446:SF3 M-PHASE-SPECIFIC PLK1-INTERACTING PROTEIN M-PHASE-SPECIFIC PLK1-INTERACTING PROTEIN nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;midbody#GO:0030496;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000014317.3|UniProtKB=G3REI2 G3REI2 LRIG1 PTHR24366:SF75 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEATS AND IMMUNOGLOBULIN LIKE DOMAINS 1 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000006551.3|UniProtKB=G3RX01 G3RX01 NADSYN1 PTHR23090:SF9 NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;indole-containing compound metabolic process#GO:0042430;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide biosynthetic process#GO:0006164;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000008619.3|UniProtKB=G3QZW1 G3QZW1 ODAD3 PTHR46518:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 151 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 3 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cilium movement#GO:0003341;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;axoneme assembly#GO:0035082 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000014052.3|UniProtKB=A0A2I2ZAS0 A0A2I2ZAS0 SLC35C2 PTHR11132:SF238 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER H1 antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleotide-sugar transmembrane transport#GO:0015780 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;cis-Golgi network#GO:0005801;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040655.1|UniProtKB=A0A2I2ZKU5 A0A2I2ZKU5 PTHR24264:SF55 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000006132.3|UniProtKB=A0A2I2Z2E1 A0A2I2Z2E1 WDR45B PTHR11227:SF18 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 3 phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289 polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;glycogen catabolic process#GO:0005980;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016071.3|UniProtKB=G3RJ05 G3RJ05 DIPK1B PTHR21093:SF3 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1B GORGO|Ensembl=ENSGGOG00000002336.3|UniProtKB=G3QIT1 G3QIT1 GSR PTHR42737:SF2 GLUTATHIONE REDUCTASE GLUTATHIONE REDUCTASE, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;disulfide oxidoreductase activity#GO:0015036;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660 cellular response to chemical stimulus#GO:0070887;glutathione metabolic process#GO:0006749;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;homeostatic process#GO:0042592;modified amino acid metabolic process#GO:0006575;cellular response to stimulus#GO:0051716;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;metabolic process#GO:0008152;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;sulfur compound metabolic process#GO:0006790;response to stress#GO:0006950;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000041849.1|UniProtKB=A0A2I2ZUN1 A0A2I2ZUN1 LOC109026322 PTHR11524:SF12 60S RIBOSOMAL PROTEIN L7 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000037188.1|UniProtKB=A0A2I2ZX68 A0A2I2ZX68 PTHR11960:SF14 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 CCKR signaling map#P06959>EIF4E#P07094;p38 MAPK pathway#P05918>eIF4E#P06024 GORGO|Ensembl=ENSGGOG00000005870.3|UniProtKB=G3QSU9 G3QSU9 WDR13 PTHR22838:SF4 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 13 chromatin binding#GO:0003682;binding#GO:0005488 GORGO|Ensembl=ENSGGOG00000000007.3|UniProtKB=G3QCR3 G3QCR3 DRC1 PTHR21625:SF1 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX PROTEIN 1 axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium or flagellum-dependent cell motility#GO:0001539;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell projection organization#GO:0030030;regulation of microtubule-based movement#GO:0060632;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607 cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000014530.3|UniProtKB=G3RF18 G3RF18 CEACAM16 PTHR44427:SF10 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM16 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000043487.1|UniProtKB=A0A2I2ZPV1 A0A2I2ZPV1 ZNF267 PTHR24393:SF187 ZINC FINGER PROTEIN ZINC FINGER PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000005042.3|UniProtKB=G3QQR4 G3QQR4 ADIG PTHR38499:SF1 ADIPOGENIN ADIPOGENIN GORGO|Ensembl=ENSGGOG00000011598.3|UniProtKB=A0A2I2YIC7 A0A2I2YIC7 TM2D3 PTHR21016:SF7 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 3 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;positive regulation of Notch signaling pathway#GO:0045747;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154 GORGO|Ensembl=ENSGGOG00000011028.3|UniProtKB=G3R611 G3R611 CST6 PTHR47033:SF1 CYSTATIN-M CYSTATIN-M endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;epidermis development#GO:0008544;tissue development#GO:0009888;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000007663.3|UniProtKB=G3SGE4 G3SGE4 PRSS21 PTHR24253:SF79 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 41 catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000026808.2|UniProtKB=G3S1W3 G3S1W3 CDSN PTHR23207:SF2 CORNEODESMOSIN CORNEODESMOSIN animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;animal organ morphogenesis#GO:0009887;skin development#GO:0043588 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000885.3|UniProtKB=G3QF09 G3QF09 RLIM PTHR45931:SF4 SI:CH211-59O9.10 E3 UBIQUITIN-PROTEIN LIGASE RLIM catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;heterochromatin formation#GO:0031507;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008324.3|UniProtKB=G3QZ35 G3QZ35 NAGS PTHR23342:SF22 N-ACETYLGLUTAMATE SYNTHASE N-ACETYLGLUTAMATE SYNTHASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;transferase activity#GO:0016740 L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 Arginine biosynthesis#P02728>N-acetylglutamate synthase#P02848 GORGO|Ensembl=ENSGGOG00000016113.3|UniProtKB=G3RE92 G3RE92 PTHR24300:SF409 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2A13 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 secondary metabolic process#GO:0019748;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;cellular response to xenobiotic stimulus#GO:0071466;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;olefinic compound metabolic process#GO:0120254;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;oxygenase#PC00177 Nicotine degradation#P05914>CYP2A6#P05984 GORGO|Ensembl=ENSGGOG00000006097.3|UniProtKB=G3QTE9 G3QTE9 SYT4 PTHR10024:SF114 SYNAPTOTAGMIN SYNAPTOTAGMIN-4 molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299;protein binding#GO:0005515;SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488 trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;membrane fusion#GO:0061025;positive regulation of cellular process#GO:0048522;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;membrane organization#GO:0061024;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;export from cell#GO:0140352;regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;synaptic signaling#GO:0099536;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;synaptic vesicle exocytosis#GO:0016079;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836 secretory vesicle#GO:0099503;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;axon#GO:0030424;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 Gonadotropin-releasing hormone receptor pathway#P06664>Syt IV#P06746 GORGO|Ensembl=ENSGGOG00000013725.3|UniProtKB=G3SGU6 G3SGU6 PGM2 PTHR45745:SF3 PHOSPHOMANNOMUTASE 45A PHOSPHOPENTOMUTASE isomerase activity#GO:0016853;intramolecular phosphotransferase activity#GO:0016868;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;purine nucleoside metabolic process#GO:0042278;nucleobase-containing compound biosynthetic process#GO:0034654;purine-containing compound biosynthetic process#GO:0072522;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;isomerase#PC00135;mutase#PC00160 GORGO|Ensembl=ENSGGOG00000003871.3|UniProtKB=G3QMQ2 G3QMQ2 LKAAEAR1 PTHR35665:SF1 PROTEIN LKAAEAR1 PROTEIN LKAAEAR1 GORGO|Ensembl=ENSGGOG00000000880.3|UniProtKB=G3QF06 G3QF06 LOC101144630 PTHR48018:SF81 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006083.3|UniProtKB=G3QTE2 G3QTE2 PAPOLG PTHR10682:SF6 POLY A POLYMERASE POLY(A) POLYMERASE GAMMA transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006219.3|UniProtKB=G3SCM5 G3SCM5 PTHR46513:SF43 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 5-LIKE PROTEIN transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012204.3|UniProtKB=G3SJ75 G3SJ75 UBA7 PTHR10953:SF143 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 7 ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein modification by small protein conjugation#GO:0032446;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;immune response#GO:0006955;response to other organism#GO:0051707;post-translational protein modification#GO:0043687;DNA damage response#GO:0006974;innate immune response#GO:0045087;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;defense response#GO:0006952;response to external stimulus#GO:0009605;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;ISG15-protein conjugation#GO:0032020;response to external biotic stimulus#GO:0043207;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492;Ubiquitin proteasome pathway#P00060>E3#P01490 GORGO|Ensembl=ENSGGOG00000039510.1|UniProtKB=A0A2I2ZW74 A0A2I2ZW74 PTHR10978:SF14 SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900 oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000022799.2|UniProtKB=G3SHM1 G3SHM1 RPL9 PTHR11655:SF46 60S/50S RIBOSOMAL PROTEIN L6/L9 LARGE RIBOSOMAL SUBUNIT PROTEIN UL6 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000015077.3|UniProtKB=G3RGG2 G3RGG2 TREM2 PTHR11860:SF54 POLYMERIC-IMMUNOGLOBULIN RECEPTOR TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 positive regulation of inflammatory response#GO:0050729;positive regulation of leukocyte activation#GO:0002696;regulation of MAPK cascade#GO:0043408;regulation of endocytosis#GO:0030100;positive regulation of response to external stimulus#GO:0032103;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of macrophage activation#GO:0043030;regulation of response to external stimulus#GO:0032101;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of multicellular organismal process#GO:0051239;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;positive regulation of signaling#GO:0023056;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of response to stress#GO:0080134;regulation of cell projection organization#GO:0031344;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of innate immune response#GO:0045088;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;positive regulation of endocytosis#GO:0045807;positive regulation of cell activation#GO:0050867;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;positive regulation of calcium-mediated signaling#GO:0050850;regulation of immune response#GO:0050776;cell communication#GO:0007154;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of calcium-mediated signaling#GO:0050848 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000028036.2|UniProtKB=G3S0R5 G3S0R5 PTHR11620:SF110 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000042305.1|UniProtKB=A0A2I2YXK7 A0A2I2YXK7 PTHR11986:SF117 AMINOTRANSFERASE CLASS III ORNITHINE AMINOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000025793.2|UniProtKB=G3S2U0 G3S2U0 LOC101137284 PTHR48002:SF123 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4B1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000017006.3|UniProtKB=G3RLF3 G3RLF3 FGL1 PTHR19143:SF263 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN-LIKE PROTEIN 1 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of cell adhesion#GO:0030155;regulation of T cell activation#GO:0050863;negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cell activation#GO:0050866;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune response#GO:0050776;negative regulation of T cell activation#GO:0050868 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000007460.3|UniProtKB=G3QWX7 G3QWX7 GHRH PTHR11213:SF6 GLUCAGON-FAMILY NEUROPEPTIDE SOMATOLIBERIN protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;binding#GO:0005488;neuropeptide hormone activity#GO:0005184;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664 secretion by cell#GO:0032940;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;hormone secretion#GO:0046879;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;export from cell#GO:0140352;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;regulation of localization#GO:0032879;hormone transport#GO:0009914;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;peptide hormone secretion#GO:0030072;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;peptide secretion#GO:0002790;signal release#GO:0023061;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of signal transduction#GO:0009967;establishment of localization#GO:0051234;positive regulation of intracellular signal transduction#GO:1902533;transport#GO:0006810;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705 cell junction#GO:0030054;axon terminus#GO:0043679;perikaryon#GO:0043204;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;presynapse#GO:0098793;extracellular region#GO:0005576;axon#GO:0030424;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;distal axon#GO:0150034;neuron projection terminus#GO:0044306;neuronal cell body#GO:0043025;cell projection#GO:0042995;cell body#GO:0044297 neuropeptide#PC00162 GORGO|Ensembl=ENSGGOG00000000041.3|UniProtKB=G3QCU2 G3QCU2 CBX5 PTHR22812:SF85 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 5 chromatin binding#GO:0003682;binding#GO:0005488 heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;heterochromatin#GO:0000792 GORGO|Ensembl=ENSGGOG00000015134.3|UniProtKB=G3RGL7 G3RGL7 ZBTB26 PTHR24399:SF14 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 26 sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000041237.1|UniProtKB=A0A2I2Z0V7 A0A2I2Z0V7 LANCL1 PTHR12736:SF5 LANC-LIKE PROTEIN GLUTATHIONE S-TRANSFERASE LANCL1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to toxic substance#GO:0009636;regulation of cellular response to alcohol#GO:1905957;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;cellular detoxification#GO:1990748;regulation of abscisic acid-activated signaling pathway#GO:0009787;cellular response to chemical stimulus#GO:0070887;regulation of response to alcohol#GO:1901419;cellular process#GO:0009987;cellular response to toxic substance#GO:0097237;biological regulation#GO:0065007;detoxification#GO:0098754;regulation of signal transduction#GO:0009966;response to chemical#GO:0042221;regulation of response to stimulus#GO:0048583 GORGO|Ensembl=ENSGGOG00000000543.3|UniProtKB=G3QE49 G3QE49 LAPTM4B PTHR12479:SF6 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4B regulation of membrane permeability#GO:0090559;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006075.3|UniProtKB=G3QTC9 G3QTC9 HLF PTHR11988:SF28 THYROTROPH EMBRYONIC FACTOR RELATED HEPATIC LEUKEMIA FACTOR nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000015140.3|UniProtKB=G3RGM6 G3RGM6 DIPK2A PTHR32073:SF6 GH11358P DIVERGENT PROTEIN KINASE DOMAIN 2A negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;regulation of apoptotic process#GO:0042981;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896 coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;COPI-coated vesicle#GO:0030137;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle coat#GO:0030120;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000021947.2|UniProtKB=G3RS14 G3RS14 C4H5orf15 PTHR16502:SF0 KERATINOCYTE-ASSOCIATED TRANSMEMBRANE PROTEIN 2 KERATINOCYTE-ASSOCIATED TRANSMEMBRANE PROTEIN 2 GORGO|Ensembl=ENSGGOG00000009981.3|UniProtKB=G3R3C0 G3R3C0 PPP1CA PTHR11668:SF377 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE PP1-ALPHA CATALYTIC SUBUNIT catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of circadian rhythm#GO:0042752 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 GORGO|Ensembl=ENSGGOG00000041947.1|UniProtKB=A0A2I2Z500 A0A2I2Z500 PTHR11476:SF6 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101 mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000011099.3|UniProtKB=G3R678 G3R678 GATB PTHR11659:SF5 GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000015778.3|UniProtKB=G3SID3 G3SID3 SHE PTHR15127:SF29 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN E protein binding#GO:0005515;binding#GO:0005488 GORGO|Ensembl=ENSGGOG00000034968.2|UniProtKB=A0A2I2Z9F2 A0A2I2Z9F2 PDE11A PTHR11347:SF130 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL 3',5'-CYCLIC-AMP AND -GMP PHOSPHODIESTERASE 11A phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000024296.2|UniProtKB=G3RYF4 G3RYF4 IGKV1D-13 PTHR23267:SF480 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-13-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000014290.3|UniProtKB=G3S5R7 G3S5R7 PPP1R16A PTHR24179:SF30 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 16A enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000043221.1|UniProtKB=G3RMQ7 G3RMQ7 LOC101151378 PTHR24103:SF637 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 49-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;regulation of biological process#GO:0050789;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023411.2|UniProtKB=G3RNU0 G3RNU0 TMEM253 PTHR37359:SF1 TRANSMEMBRANE PROTEIN 253 TRANSMEMBRANE PROTEIN 253 GORGO|Ensembl=ENSGGOG00000042639.1|UniProtKB=G3R622 G3R622 LOC129533225 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of protein stability#GO:0031647;regulation of apoptotic process#GO:0042981 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000011363.3|UniProtKB=G3R6V8 G3R6V8 PRDM14 PTHR16515:SF74 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 14 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003194.3|UniProtKB=A0A2I2Y3T0 A0A2I2Y3T0 PTHR14200:SF14 CYTOCHROME C OXIDASE POLYPEPTIDE CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796 oxidase#PC00175;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000016556.3|UniProtKB=G3RK99 G3RK99 TIMELESS PTHR22940:SF4 TIMEOUT/TIMELESS-2 PROTEIN TIMELESS HOMOLOG DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of DNA-templated DNA replication#GO:0090329;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;DNA integrity checkpoint signaling#GO:0031570;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of DNA-templated DNA replication#GO:2000104;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA replication#GO:0006275;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786 replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000012727.3|UniProtKB=G3RAF0 G3RAF0 PPID PTHR11071:SF594 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000003664.3|UniProtKB=G3SBH6 G3SBH6 KDM1A PTHR10742:SF423 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;chromatin binding#GO:0003682;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;heterocyclic compound binding#GO:1901363;histone demethylase activity#GO:0032452;histone modifying activity#GO:0140993;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000000432.3|UniProtKB=G3SF73 G3SF73 OPCML PTHR42757:SF17 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED OPIOID-BINDING PROTEIN_CELL ADHESION MOLECULE regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;cell adhesion#GO:0007155;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;regulation of biological process#GO:0050789;cell-cell adhesion#GO:0098609;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128 postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;plasma membrane#GO:0005886;postsynaptic density#GO:0014069;cell junction#GO:0030054 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000005253.3|UniProtKB=G3QRA1 G3QRA1 MATCAP2 PTHR31817:SF3 FAMILY NOT NAMED TYROSINE CARBOXYPEPTIDASE MATCAP2-RELATED GORGO|Ensembl=ENSGGOG00000040046.1|UniProtKB=A0A2I2ZRW8 A0A2I2ZRW8 PTHR23267:SF483 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-25 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000024590.2|UniProtKB=A0A2I2Z695 A0A2I2Z695 PTHR20996:SF3 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 SUBFAMILY NOT NAMED cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000040335.1|UniProtKB=A0A2I2Z5T4 A0A2I2Z5T4 PTHR28358:SF1 TRANSMEMBRANE PROTEIN 127 TRANSMEMBRANE PROTEIN 127 regulation of biological process#GO:0050789;regulation of TOR signaling#GO:0032006;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011029.3|UniProtKB=G3R613 G3R613 SAMD8 PTHR21290:SF69 SPHINGOMYELIN SYNTHETASE SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1 phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 ceramide metabolic process#GO:0006672;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002638.3|UniProtKB=G3QJK3 G3QJK3 PTHR13077:SF7 SELENOPROTEIN F SELENOPROTEIN M catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000006559.3|UniProtKB=G3QUL8 G3QUL8 LONP2 PTHR10046:SF24 ATP DEPENDENT LON PROTEASE FAMILY MEMBER LON PROTEASE HOMOLOG 2, PEROXISOMAL hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;localization#GO:0051179;protein metabolic process#GO:0019538;proteolysis#GO:0006508;protein targeting#GO:0006605;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000014967.3|UniProtKB=G3RG63 G3RG63 ISG15 PTHR10666:SF267 UBIQUITIN UBIQUITIN-LIKE PROTEIN ISG15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 response to external stimulus#GO:0009605;defense response#GO:0006952;macromolecule metabolic process#GO:0043170;innate immune response#GO:0045087;post-translational protein modification#GO:0043687;response to other organism#GO:0051707;immune response#GO:0006955;protein metabolic process#GO:0019538;response to virus#GO:0009615;macromolecule modification#GO:0043412;response to bacterium#GO:0009617;response to external biotic stimulus#GO:0043207;ISG15-protein conjugation#GO:0032020;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;protein catabolic process#GO:0030163;defense response to bacterium#GO:0042742;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;protein modification by small protein conjugation#GO:0032446;defense response to virus#GO:0051607 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;nucleus#GO:0005634;ribosome#GO:0005840;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011469.3|UniProtKB=G3R755 G3R755 PTHR43888:SF9 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 4 ATPase activator activity#GO:0001671;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;protein folding#GO:0006457;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein refolding#GO:0042026;cellular response to heat#GO:0034605;response to heat#GO:0009408;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000002960.3|UniProtKB=G3SHX2 G3SHX2 SLC5A1 PTHR11819:SF197 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 1 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;sugar transmembrane transporter activity#GO:0051119;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;solute:sodium symporter activity#GO:0015370 system process#GO:0003008;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;renal absorption#GO:0070293;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643;carbohydrate transmembrane transport#GO:0034219;multicellular organismal process#GO:0032501;import across plasma membrane#GO:0098739;cellular process#GO:0009987;renal system process#GO:0003014;D-glucose transmembrane transport#GO:1904659 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023691.2|UniProtKB=G3RSI1 G3RSI1 RNF208 PTHR22791:SF3 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF182-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000028587.2|UniProtKB=G3SHA6 G3SHA6 LOC101148218 PTHR26453:SF38 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13J1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000023805.2|UniProtKB=G3SHC3 G3SHC3 BMP2K PTHR22967:SF10 SERINE/THREONINE PROTEIN KINASE BMP-2-INDUCIBLE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;phosphotransferase activity, alcohol group as acceptor#GO:0016773;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;catalytic activity, acting on a protein#GO:0140096 regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;positive regulation of signaling#GO:0023056;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of signal transduction#GO:0009967;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of cellular component organization#GO:0051128;positive regulation of Notch signaling pathway#GO:0045747;regulation of receptor-mediated endocytosis#GO:0048259;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of endocytosis#GO:0030100;regulation of response to stimulus#GO:0048583;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of multicellular organismal process#GO:0051239;regulation of bone mineralization#GO:0030500;positive regulation of response to stimulus#GO:0048584 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008213.3|UniProtKB=A0A2I2Z102 A0A2I2Z102 CEP250 PTHR23159:SF1 CENTROSOMAL PROTEIN 2 CENTROSOME-ASSOCIATED PROTEIN CEP250 cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000389.3|UniProtKB=G3QDQ7 G3QDQ7 RRP8 PTHR12787:SF0 RIBOSOMAL RNA-PROCESSING PROTEIN 8 RIBOSOMAL RNA-PROCESSING PROTEIN 8 catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleolus organization#GO:0007000;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889 organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000014175.3|UniProtKB=G3RE54 G3RE54 UCMA PTHR28647:SF2 UNIQUE CARTILAGE MATRIX-ASSOCIATED PROTEIN UNIQUE CARTILAGE MATRIX-ASSOCIATED PROTEIN system development#GO:0048731;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;embryo development ending in birth or egg hatching#GO:0009792;developmental process#GO:0032502;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development#GO:0009790;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000021973.2|UniProtKB=G3SD12 G3SD12 CELF3 PTHR24012:SF739 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000024118.3|UniProtKB=G3S7B6 G3S7B6 CRISP2 PTHR10334:SF572 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN 2 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010742.3|UniProtKB=G3R5A2 G3R5A2 CCER1 PTHR37337:SF1 COILED-COIL DOMAIN-CONTAINING GLUTAMATE-RICH PROTEIN 1 COILED-COIL DOMAIN-CONTAINING GLUTAMATE-RICH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000038786.1|UniProtKB=A0A2I2Z5R1 A0A2I2Z5R1 PTCH2 PTHR46022:SF3 PROTEIN PATCHED PROTEIN PATCHED HOMOLOG 2 protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;transmembrane signaling receptor activity#GO:0004888 negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000014933.3|UniProtKB=G3S1K0 G3S1K0 CISH PTHR10155:SF9 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT CYTOKINE-INDUCIBLE SH2-CONTAINING PROTEIN binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;protein binding#GO:0005515 cell communication#GO:0007154;response to peptide#GO:1901652;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;cytokine-mediated signaling pathway#GO:0019221;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;cell surface receptor signaling pathway#GO:0007166;negative regulation of response to stimulus#GO:0048585;response to chemical#GO:0042221;response to cytokine#GO:0034097;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 kinase modulator#PC00140 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879;Interferon-gamma signaling pathway#P00035>SOCS#P00956 GORGO|Ensembl=ENSGGOG00000009654.3|UniProtKB=G3R2H5 G3R2H5 ZNF19 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000024740.2|UniProtKB=A0A2I2Y6H3 A0A2I2Y6H3 PTHR48043:SF86 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2B10-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;hexosyltransferase activity#GO:0016758 estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;hormone metabolic process#GO:0042445;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817 GORGO|Ensembl=ENSGGOG00000011420.3|UniProtKB=G3R709 G3R709 PTHR14136:SF31 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 POTASSIUM CHANNEL TETRAMERISATION-TYPE BTB DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000006831.3|UniProtKB=A0A2I2Z219 A0A2I2Z219 TRMT5 PTHR23245:SF44 TRNA METHYLTRANSFERASE TRNA (GUANINE(37)-N(1))-METHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;mitochondrial RNA modification#GO:1900864;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000002036.3|UniProtKB=G3RMI2 G3RMI2 LOC101147858 PTHR46255:SF2 SHORT STATURE HOMEOBOX SHORT STATURE HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 GORGO|Gene=IGHA1|UniProtKB=P20758 P20758 IGHA1 PTHR23411:SF31 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT ALPHA 1-RELATED antigen binding#GO:0003823;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;biological regulation#GO:0065007;response to other organism#GO:0051707;adaptive immune response#GO:0002250;positive regulation of response to stimulus#GO:0048584;complement activation#GO:0006956;immune response#GO:0006955;response to external stimulus#GO:0009605;defense response#GO:0006952;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;defense response to bacterium#GO:0042742;immune system process#GO:0002376;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;antibacterial humoral response#GO:0019731;immune effector process#GO:0002252;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000007999.3|UniProtKB=G3RWL2 G3RWL2 LMNB1 PTHR45721:SF3 LAMIN DM0-RELATED LAMIN-B1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular localization#GO:0051641;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;establishment of organelle localization#GO:0051656;transport#GO:0006810;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;protein localization to nucleus#GO:0034504;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;macromolecule localization#GO:0033036;negative regulation of biosynthetic process#GO:0009890;membrane organization#GO:0061024;chromatin organization#GO:0006325;biological regulation#GO:0065007;localization within membrane#GO:0051668;organelle localization#GO:0051640;localization#GO:0051179;nuclear migration#GO:0007097;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular organelle#GO:0043229 FAS signaling pathway#P00020>Nuclear Lamin#P00616 GORGO|Ensembl=ENSGGOG00000010317.3|UniProtKB=G3R475 G3R475 LOC101123872 PTHR23101:SF122 RAB GDP/GTP EXCHANGE FACTOR RAB5 GDP_GTP EXCHANGE FACTOR enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular vesicle#GO:0097708;cytosol#GO:0005829;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000025059.2|UniProtKB=G3S6C1 G3S6C1 PTHR10666:SF471 UBIQUITIN UBIQUITIN-LIKE FUBI-RIBOSOMAL PROTEIN ES30 FUSION PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000004583.3|UniProtKB=G3QPK0 G3QPK0 TRUB1 PTHR13767:SF2 TRNA-PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE TRUB1 isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;pseudouridine synthesis#GO:0001522;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000005485.3|UniProtKB=G3QRV9 G3QRV9 TMX3 PTHR46426:SF1 PROTEIN DISULFIDE-ISOMERASE TMX3 PROTEIN DISULFIDE-ISOMERASE TMX3 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell surface#GO:0009986 chaperone#PC00072 GORGO|Gene=PTTG1|UniProtKB=A1YF19 A1YF19 PTTG1 PTHR10418:SF7 SECURIN-3 SECURIN molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 organelle organization#GO:0006996;cellular process#GO:0009987;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;meiotic chromosome segregation#GO:0045132;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;reproductive process#GO:0022414;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cell cycle#GO:0007049;cell cycle process#GO:0022402;organelle fission#GO:0048285;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000027036.2|UniProtKB=G3RTQ2 G3RTQ2 YKT6 PTHR45806:SF1 SYNAPTOBREVIN HOMOLOG YKT6 SYNAPTOBREVIN HOMOLOG YKT6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 catabolic process#GO:0009056;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;intra-Golgi vesicle-mediated transport#GO:0006891;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;vacuole fusion#GO:0097576;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;vacuole fusion, non-autophagic#GO:0042144;macroautophagy#GO:0016236;membrane organization#GO:0061024;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987;autophagy#GO:0006914;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;metabolic process#GO:0008152;transport#GO:0006810;Golgi vesicle transport#GO:0048193 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;Golgi apparatus#GO:0005794;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;vesicle#GO:0031982;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000016652.3|UniProtKB=G3RKI4 G3RKI4 WDR4 PTHR16288:SF0 WD40 REPEAT PROTEIN 4 TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT WDR4 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 organelle#GO:0043226;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012846.3|UniProtKB=G3RAQ8 G3RAQ8 DEK PTHR13468:SF24 DEK PROTEIN PROTEIN DEK protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004430.3|UniProtKB=G3QP60 G3QP60 PSMD6 PTHR14145:SF1 26S PROTESOME SUBUNIT 6 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;proteasome regulatory particle, lid subcomplex#GO:0008541 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000010199.3|UniProtKB=G3R3X9 G3R3X9 HMCN2 PTHR45080:SF28 CONTACTIN 5 HEMICENTIN-2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell junction organization#GO:0034330;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;synapse organization#GO:0050808 axon#GO:0030424;membrane#GO:0016020;cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;neuronal cell body#GO:0043025;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000015454.3|UniProtKB=G3RHF6 G3RHF6 TRAPPC13 PTHR13134:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;TRAPP complex#GO:0030008;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000008911.3|UniProtKB=A0A2I2YYF2 A0A2I2YYF2 PTHR15725:SF13 ZN-FINGER, C-X8-C-X5-C-X3-H TYPE-CONTAINING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 11B-RELATED RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000000694.3|UniProtKB=G3QEI7 G3QEI7 ALKBH4 PTHR12463:SF0 OXYGENASE-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 4 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 midbody#GO:0030496;contractile ring#GO:0070938;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000003457.3|UniProtKB=A0A2I2ZBI3 A0A2I2ZBI3 LGALS3 PTHR11346:SF26 GALECTIN GALECTIN-3 laminin binding#GO:0043236;binding#GO:0005488;oligosaccharide binding#GO:0070492;protein-containing complex binding#GO:0044877;extracellular matrix binding#GO:0050840;carbohydrate binding#GO:0030246;protein binding#GO:0005515 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of cellular component organization#GO:0051128;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;mononuclear cell migration#GO:0071674;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;positive regulation of transport#GO:0051050;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive chemotaxis#GO:0050918;negative regulation of signal transduction#GO:0009968;granulocyte migration#GO:0097530;taxis#GO:0042330;response to chemical#GO:0042221;neutrophil migration#GO:1990266;regulation of apoptotic process#GO:0042981;regulation of endocytosis#GO:0030100;neutrophil chemotaxis#GO:0030593;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular response to stimulus#GO:0051716;negative regulation of cellular component organization#GO:0051129;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of cell communication#GO:0010646;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;negative regulation of transport#GO:0051051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;chemotaxis#GO:0006935;cell chemotaxis#GO:0060326;macrophage chemotaxis#GO:0048246;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;regulation of calcium ion transport#GO:0051924;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cell migration#GO:0016477;regulation of monoatomic ion transport#GO:0043269;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;leukocyte migration#GO:0050900;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;nucleus#GO:0005634;cell periphery#GO:0071944 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000005720.3|UniProtKB=G3QSG5 G3QSG5 TOMM40L PTHR10802:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40B transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031 cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004775.3|UniProtKB=G3QQ18 G3QQ18 CCR9 PTHR10489:SF664 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 9 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000008878.3|UniProtKB=G3RZ64 G3RZ64 VAT1 PTHR44054:SF1 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE NADPH-DEPENDENT QUINONE OXIDOREDUCTASE VAT1 regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 Huntington disease#P00029>PIG3#G01535 GORGO|Ensembl=ENSGGOG00000012413.3|UniProtKB=G3R9M4 G3R9M4 MINAR1 PTHR31530:SF2 MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 MINAR1 FAMILY MEMBER MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 negative regulation of cell communication#GO:0010648;regulation of cell population proliferation#GO:0042127;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of TOR signaling#GO:0032006;negative regulation of cell population proliferation#GO:0008285 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027001.2|UniProtKB=G3RMA8 G3RMA8 LOC101148018 PTHR11818:SF145 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN D structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory system development#GO:0048880;multicellular organismal process#GO:0032501 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000014824.3|UniProtKB=G3SF68 G3SF68 BRD7 PTHR22881:SF12 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN-CONTAINING PROTEIN 7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000005069.3|UniProtKB=G3RP52 G3RP52 VNN3P PTHR10609:SF4 BIOTINIDASE-RELATED VASCULAR NON-INFLAMMATORY MOLECULE 3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;small molecule metabolic process#GO:0044281 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000016928.3|UniProtKB=G3RL81 G3RL81 LRRC25 PTHR20878:SF0 LEUCINE-RICH REPEAT CONTAINING PROTEIN 25 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 25 GORGO|Ensembl=ENSGGOG00000015727.3|UniProtKB=A0A2I2Y5D6 A0A2I2Y5D6 DMKN PTHR36881:SF1 DERMOKINE DERMOKINE membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;membrane assembly#GO:0071709;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005074.3|UniProtKB=G3QQV3 G3QQV3 PTPRA PTHR19134:SF433 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ALPHA hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000005637.3|UniProtKB=G3QS91 G3QS91 PODN PTHR45712:SF20 AGAP008170-PA PODOCAN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000001395.3|UniProtKB=G3QGC4 G3QGC4 TBC1D16 PTHR22957:SF547 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 16 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000011912.3|UniProtKB=G3S825 G3S825 EXOC3L1 PTHR21292:SF12 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810 exocyst#GO:0000145;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012453.3|UniProtKB=A0A2I2ZWC8 A0A2I2ZWC8 OLFML3 PTHR23192:SF8 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 3 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000004921.3|UniProtKB=G3QQF5 G3QQF5 CBLL1 PTHR13480:SF2 E3 UBIQUITIN-PROTEIN LIGASE HAKAI-RELATED E3 UBIQUITIN-PROTEIN LIGASE HAKAI catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;cellular process#GO:0009987;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000016426.3|UniProtKB=A0A2I2YYB0 A0A2I2YYB0 GCLM PTHR13295:SF4 GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;ligase#PC00142 GORGO|Ensembl=ENSGGOG00000001117.3|UniProtKB=G3QFM5 G3QFM5 PGGT1B PTHR11774:SF4 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000014601.3|UniProtKB=G3RF86 G3RF86 SEMA4C PTHR11036:SF16 SEMAPHORIN SEMAPHORIN-4C binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;response to chemical#GO:0042221;taxis#GO:0042330;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon guidance#GO:0007411;axon development#GO:0061564;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000038663.1|UniProtKB=A0A2I2YGJ4 A0A2I2YGJ4 TRAV29DV5 PTHR19343:SF24 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 29_DELTA VARIABLE 5 peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000001213.3|UniProtKB=G3QFW2 G3QFW2 OMA1 PTHR22726:SF1 METALLOENDOPEPTIDASE OMA1 METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000000025.3|UniProtKB=G3S700 G3S700 MMP15 PTHR10201:SF25 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-15 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141 GORGO|Ensembl=ENSGGOG00000027624.2|UniProtKB=A0A2I2YIX3 A0A2I2YIX3 RAB14 PTHR24073:SF185 DRAB5-RELATED RAS-RELATED PROTEIN RAB-14 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;lytic vacuole organization#GO:0080171;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;phagolysosome assembly#GO:0001845;intracellular transport#GO:0046907;phagocytosis#GO:0006909;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;Golgi to endosome transport#GO:0006895;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;endocytosis#GO:0006897;organelle assembly#GO:0070925;post-Golgi vesicle-mediated transport#GO:0006892;vacuole organization#GO:0007033;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endocytic vesicle#GO:0030139;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000001696.3|UniProtKB=G3QH51 G3QH51 SFRP2 PTHR11309:SF45 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 2 Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;non-canonical Wnt signaling pathway#GO:0035567;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434 GORGO|Ensembl=ENSGGOG00000014876.3|UniProtKB=G3RFY5 G3RFY5 GCNA PTHR23099:SF0 TRANSCRIPTIONAL REGULATOR GERM CELL NUCLEAR ACIDIC PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000002463.3|UniProtKB=A0A2I2ZCL1 A0A2I2ZCL1 JKAMP PTHR12740:SF4 JNK1/MAPK8-ASSOCIATED MEMBRANE PROTEIN JNK1_MAPK8-ASSOCIATED MEMBRANE PROTEIN ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012708.3|UniProtKB=G3S5A1 G3S5A1 FAM9B PTHR19368:SF2 XLR/SCP3/FAM9 PROTEIN FAM9B cellular developmental process#GO:0048869;meiotic cell cycle#GO:0051321;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;cellular process#GO:0009987;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;sexual reproduction#GO:0019953;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;cell cycle#GO:0007049;germ cell development#GO:0007281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000036578.1|UniProtKB=A0A2I2ZHM0 A0A2I2ZHM0 TRBV16 PTHR23268:SF24 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 16 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000003806.3|UniProtKB=G3QMK0 G3QMK0 SEPHS1 PTHR10256:SF2 SELENIDE, WATER DIKINASE ZINCORE COMPONENT SEPHS1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000003867.3|UniProtKB=G3QMQ0 G3QMQ0 RGS19 PTHR10845:SF145 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 19 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789 cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 GORGO|Ensembl=ENSGGOG00000002612.3|UniProtKB=G3QJH4 G3QJH4 TCF23 PTHR23349:SF58 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 23 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000042065.1|UniProtKB=A0A2I2YTS2 A0A2I2YTS2 CTNNBIP1 PTHR47142:SF1 BETA-CATENIN-INTERACTING PROTEIN 1 BETA-CATENIN-INTERACTING PROTEIN 1 beta-catenin binding#GO:0008013;protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000005787.3|UniProtKB=G3QSM4 G3QSM4 STAR PTHR46489:SF1 STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL GORGO|Ensembl=ENSGGOG00000003751.3|UniProtKB=G3S5T1 G3S5T1 AKNA PTHR21510:SF15 AKNA DOMAIN-CONTAINING PROTEIN MICROTUBULE ORGANIZATION PROTEIN AKNA neurogenesis#GO:0022008;mesenchyme development#GO:0060485;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;mesenchymal cell differentiation#GO:0048762;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;head development#GO:0060322;nervous system development#GO:0007399;biological regulation#GO:0065007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;brain development#GO:0007420;negative regulation of cell-cell adhesion#GO:0022408;cellular process#GO:0009987;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;cell population proliferation#GO:0008283;animal gross anatomical part developmental process#GO:0160108;forebrain development#GO:0030900;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell division#GO:0051301;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080 GORGO|Ensembl=ENSGGOG00000039274.1|UniProtKB=A0A2I2ZQH4 A0A2I2ZQH4 GDNF PTHR12173:SF1 GDNF SUBFAMILY OF TGF-BETA FAMILY GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545 cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 neurotrophic factor#PC00163;intercellular signal molecule#PC00207;growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000002758.3|UniProtKB=G3QJW7 G3QJW7 CC2D2A PTHR20837:SF7 CENTROSOMAL PROTEIN-RELATED COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 2A intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;localization#GO:0051179;organelle assembly#GO:0070925;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;cilium assembly#GO:0060271 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000012305.3|UniProtKB=G3R9C6 G3R9C6 PTHR11736:SF152 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B2 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039821.1|UniProtKB=A0A2I2YF52 A0A2I2YF52 LCE2D PTHR48615:SF7 LATE CORNIFIED ENVELOPE PROTEIN 1C LATE CORNIFIED ENVELOPE PROTEIN 2A-RELATED GORGO|Ensembl=ENSGGOG00000016682.3|UniProtKB=G3SCX5 G3SCX5 IBTK PTHR22872:SF15 BTK-BINDING PROTEIN-RELATED INHIBITOR OF BRUTON TYROSINE KINASE kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000012257.3|UniProtKB=G3R994 G3R994 VAV1 PTHR45818:SF2 PROTEIN VAV PROTO-ONCOGENE VAV nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cell surface receptor signaling pathway#GO:0007166;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;small GTPase-mediated signal transduction#GO:0007264;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;intracellular signal transduction#GO:0035556;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 B cell activation#P00010>vav#P00368;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169 GORGO|Ensembl=ENSGGOG00000034877.2|UniProtKB=G3SKR1 G3SKR1 RPH3AL PTHR45729:SF4 RABPHILIN, ISOFORM A RAB EFFECTOR NOC2 positive regulation of secretion#GO:0051047;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000003566.3|UniProtKB=G3QLY0 G3QLY0 LOC101147269 PTHR14628:SF1 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN 5 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000007755.3|UniProtKB=G3QXN5 G3QXN5 PTHR46882:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY N MEMBER 1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY N MEMBER 1 phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;regulation of mRNA metabolic process#GO:1903311;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;response to hypoxia#GO:0001666;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 organelle membrane#GO:0031090;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967 GORGO|Ensembl=ENSGGOG00000000072.3|UniProtKB=G3QCW9 G3QCW9 SLC16A3 PTHR11360:SF27 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 4 solute:proton symporter activity#GO:0015295;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;monocarboxylic acid transmembrane transporter activity#GO:0008028;active transmembrane transporter activity#GO:0022804 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014672.3|UniProtKB=G3RFF1 G3RFF1 CFAP206 PTHR21442:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;male gamete generation#GO:0048232;regulation of reproductive process#GO:2000241;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;cell motility#GO:0048870;reproductive process#GO:0022414;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;regulation of biological process#GO:0050789;gamete generation#GO:0007276;cell projection organization#GO:0030030;regulation of microtubule-based movement#GO:0060632;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000014905.3|UniProtKB=G3RG08 G3RG08 PTHR11178:SF1 IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016205.3|UniProtKB=G3SAF0 G3SAF0 BCAP29 PTHR12701:SF5 BCR-ASSOCIATED PROTEIN, BAP B-CELL RECEPTOR-ASSOCIATED PROTEIN 29 protein carrier activity#GO:0140597;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104 positive regulation of metabolic process#GO:0009893;protein transport#GO:0015031;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;positive regulation of protein metabolic process#GO:0051247;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;metabolic process#GO:0008152;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;establishment of protein localization#GO:0045184;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;localization#GO:0051179;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;ERAD pathway#GO:0036503;regulation of protein catabolic process#GO:0042176;response to endoplasmic reticulum stress#GO:0034976;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;regulation of catabolic process#GO:0009894;transport#GO:0006810;biological regulation#GO:0065007;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006027.3|UniProtKB=G3QT86 G3QT86 ATAD2B PTHR23069:SF5 AAA DOMAIN-CONTAINING ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2B ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;histone binding#GO:0042393;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682 positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;transcription initiation at RNA polymerase II promoter#GO:0006367;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA-templated transcription initiation#GO:0006352;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;nucleosome organization#GO:0034728;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;transcription by RNA polymerase II#GO:0006366;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex disassembly#GO:0032984;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of biosynthetic process#GO:0009891 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000006618.3|UniProtKB=G3QUR7 G3QUR7 RAB15 PTHR47977:SF58 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-15 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924 endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;transport#GO:0006810;intracellular transport#GO:0046907 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000014696.3|UniProtKB=A0A2I2Z4S3 A0A2I2Z4S3 IQGAP2 PTHR14149:SF12 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP2 actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;calmodulin binding#GO:0005516;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 supramolecular fiber organization#GO:0097435;mitotic cytokinetic process#GO:1902410;cortical actin cytoskeleton organization#GO:0030866;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;actomyosin structure organization#GO:0031032;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cell division#GO:0051301;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;actomyosin contractile ring assembly#GO:0000915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 cell cortex#GO:0005938;cell periphery#GO:0071944;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000039669.1|UniProtKB=A0A2I2ZA43 A0A2I2ZA43 PTHR11759:SF61 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;translation#GO:0006412;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000041544.1|UniProtKB=A0A2I2ZDW7 A0A2I2ZDW7 PTHR24006:SF947 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 biological regulation#GO:0065007;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;regulation of protein stability#GO:0031647;cellular process#GO:0009987;regulation of catabolic process#GO:0009894;DNA damage response#GO:0006974;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;nucleus#GO:0005634;intracellular vesicle#GO:0097708;cytosol#GO:0005829 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000022548.2|UniProtKB=G3RM86 G3RM86 PTHR12138:SF151 PRIMATE-EXPANDED PROTEIN FAMILY TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 9 GORGO|Ensembl=ENSGGOG00000001615.3|UniProtKB=G3QGX4 G3QGX4 FAM47B PTHR47415:SF1 PROTEIN FAM47B PROTEIN FAM47B GORGO|Ensembl=ENSGGOG00000012736.3|UniProtKB=G3RAE7 G3RAE7 DDI1 PTHR12917:SF15 ASPARTYL PROTEASE DDI-RELATED PROTEIN DDI1 HOMOLOG 1 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteolysis#GO:0006508;metabolic process#GO:0008152;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of protein stability#GO:0031647;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;aspartic protease#PC00053 GORGO|Ensembl=ENSGGOG00000015697.3|UniProtKB=G3RI27 G3RI27 GPR18 PTHR24232:SF1 G-PROTEIN COUPLED RECEPTOR N-ARACHIDONYL GLYCINE RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010859.3|UniProtKB=A0A2I2YB07 A0A2I2YB07 DHCR24 PTHR10801:SF21 24-DEHYDROCHOLESTEROL REDUCTASE DELTA(24)-STEROL REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;secondary alcohol biosynthetic process#GO:1902653;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652 cellular anatomical structure#GO:0110165;membrane#GO:0016020 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000013067.3|UniProtKB=G3RBB5 G3RBB5 PMFBP1 PTHR18881:SF2 POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1-RELATED POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1 sexual reproduction#GO:0019953;developmental process#GO:0032502;spermatogenesis#GO:0007283;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;gamete generation#GO:0007276;male gamete generation#GO:0048232 cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009782.3|UniProtKB=G3R2V1 G3R2V1 WDR35 PTHR16517:SF1 TUBBY-RELATED WD REPEAT-CONTAINING PROTEIN 35 intraciliary transport#GO:0042073;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031 ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;intraciliary transport particle A#GO:0030991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040888.1|UniProtKB=G3QGV2 G3QGV2 ZNF304 PTHR24376:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 850 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000004832.3|UniProtKB=Q0MQF5 Q0MQF5 NDUFC1 PTHR17097:SF0 NADH-UBIQUINONE OXIDOREDUCTASE KFYI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C1, MITOCHONDRIAL transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007236.3|UniProtKB=G3QWC7 G3QWC7 RNF43 PTHR16200:SF2 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE RNF43 G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;signaling receptor binding#GO:0005102;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515 cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of response to stimulus#GO:0048583;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000008936.3|UniProtKB=G3RMC9 G3RMC9 CSF1R PTHR24416:SF47 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824 regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;cell migration#GO:0016477;hemopoiesis#GO:0030097;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;osteoclast differentiation#GO:0030316;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;leukocyte differentiation#GO:0002521;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;signaling#GO:0023052;cell development#GO:0048468 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010391.3|UniProtKB=G3R4E1 G3R4E1 FOXP1 PTHR45796:SF3 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P1 sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000011703.3|UniProtKB=G3R7S1 G3R7S1 OTC PTHR45753:SF8 ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL ORNITHINE TRANSCARBAMYLASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transferase#PC00220 Arginine biosynthesis#P02728>Ornithine carbamoyl transferase#P02846 GORGO|Ensembl=ENSGGOG00000006643.3|UniProtKB=A0A2I2ZEP6 A0A2I2ZEP6 RHOT1 PTHR24072:SF124 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE 1 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 microtubule-based transport#GO:0099111;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;establishment of organelle localization#GO:0051656;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;cytoskeleton organization#GO:0007010;apoptotic mitochondrial changes#GO:0008637;organelle transport along microtubule#GO:0072384;regulation of membrane permeability#GO:0090559;actin filament-based process#GO:0030029;organelle localization#GO:0051640;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;actin cytoskeleton organization#GO:0030036;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;transport#GO:0006810;intracellular transport#GO:0046907;actin filament organization#GO:0007015;mitochondrion localization#GO:0051646;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;apoptotic signaling pathway#GO:0097190;regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;cell periphery#GO:0071944;organelle outer membrane#GO:0031968;plasma membrane#GO:0005886;cytoplasm#GO:0005737 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000008480.3|UniProtKB=G3QZI4 G3QZI4 ATP2A1 PTHR42861:SF24 CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 1 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000026784.2|UniProtKB=G3S3X6 G3S3X6 ZBTB8B PTHR24394:SF33 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8B DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007186.3|UniProtKB=G3QUL6 G3QUL6 WNT3 PTHR12027:SF82 WNT RELATED PROTO-ONCOGENE WNT-3 cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 GORGO|Ensembl=ENSGGOG00000015459.3|UniProtKB=G3RHG3 G3RHG3 PIK3R6 PTHR15593:SF1 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 6 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of innate immune response#GO:0045088;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of natural killer cell mediated cytotoxicity#GO:0042269;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of immune effector process#GO:0002697;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of lymphocyte mediated immunity#GO:0002706;G protein-coupled receptor signaling pathway#GO:0007186;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;regulation of defense response#GO:0031347;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of response to biotic stimulus#GO:0002831;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of natural killer cell mediated immunity#GO:0002715;cellular response to stimulus#GO:0051716 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898;membrane protein complex#GO:0098796;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Endothelin signaling pathway#P00019>PI3K#P00577;EGF receptor signaling pathway#P00018>PI3K#P00557 GORGO|Ensembl=ENSGGOG00000002258.3|UniProtKB=G3QIL5 G3QIL5 NOTCH3 PTHR24044:SF415 NOTCH LIGAND FAMILY MEMBER NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 3 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;negative regulation of Notch signaling pathway#GO:0045746;Notch signaling pathway#GO:0007219 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>NIct#P01119;Notch signaling pathway#P00045>Notch#P01099;Alzheimer disease-presenilin pathway#P00004>NICD#P00122;Notch signaling pathway#P00045>Next#P01103;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Notch signaling pathway#P00045>Ntm#P01114;Notch signaling pathway#P00045>NIcs#P01120;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171 GORGO|Ensembl=ENSGGOG00000022827.2|UniProtKB=G3SET5 G3SET5 LMAN2 PTHR12223:SF36 VESICULAR MANNOSE-BINDING LECTIN VESICULAR INTEGRAL-MEMBRANE PROTEIN VIP36 small molecule binding#GO:0036094;binding#GO:0005488;monosaccharide binding#GO:0048029;carbohydrate binding#GO:0030246 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;COPII-coated ER to Golgi transport vesicle#GO:0030134 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000017150.3|UniProtKB=G3RLS7 G3RLS7 SUN3 PTHR12911:SF24 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;membrane#GO:0016020;nucleus#GO:0005634 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000012068.3|UniProtKB=G3R8R8 G3R8R8 KIAA0319L PTHR46182:SF3 FI19480P1 DYSLEXIA-ASSOCIATED PROTEIN KIAA0319-LIKE PROTEIN cellular process#GO:0009987;cell differentiation#GO:0030154;cell migration#GO:0016477;cell motility#GO:0048870;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;generation of neurons#GO:0048699;neuron migration#GO:0001764;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000022519.2|UniProtKB=A0A2I2Y7J8 A0A2I2Y7J8 PTHR10836:SF104 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE NAD(P) BINDING DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891 ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000043098.1|UniProtKB=A0A2I2ZTP6 A0A2I2ZTP6 APOLD1 PTHR14096:SF1 APOLIPOPROTEIN L APOLIPOPROTEIN L DOMAIN-CONTAINING PROTEIN 1 lipid binding#GO:0008289;binding#GO:0005488 regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of developmental process#GO:0050793;blood vessel morphogenesis#GO:0048514;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;regulation of multicellular organismal process#GO:0051239;tube development#GO:0035295;biological regulation#GO:0065007;regulation of epithelial cell differentiation#GO:0030856;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000039962.1|UniProtKB=A0A2I2Z775 A0A2I2Z775 PTHR37876:SF1 PROTEIN GAR2-LIKE SPERMATID NUCLEAR TRANSITION PROTEIN 4 GORGO|Ensembl=ENSGGOG00000015574.3|UniProtKB=G3SG65 G3SG65 HCRT PTHR15173:SF2 OREXIN HYPOCRETIN NEUROPEPTIDE PRECURSOR GORGO|Ensembl=ENSGGOG00000026235.2|UniProtKB=G3S1D2 G3S1D2 C1GALT1C1 PTHR23033:SF2 BETA1,3-GALACTOSYLTRANSFERASE C1GALT1-SPECIFIC CHAPERONE 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;galactosyltransferase activity#GO:0008378;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000010890.3|UniProtKB=G3R5N7 G3R5N7 ADGRG7 PTHR12011:SF305 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G7 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000303.3|UniProtKB=G3SE43 G3SE43 MMP23B PTHR10201:SF7 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-23 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000016111.3|UniProtKB=G3RJ42 G3RJ42 TMED5 PTHR22811:SF41 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Gene=TAS2R16|UniProtKB=Q645Y4 Q645Y4 TAS2R16 PTHR11394:SF68 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 16 molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004749.3|UniProtKB=G3RU24 G3RU24 USP48 PTHR24006:SF722 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 48 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000005361.3|UniProtKB=G3QRJ2 G3QRJ2 RMI2 PTHR33962:SF1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 RMI2 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;regulation of chromosome segregation#GO:0051983;DNA repair#GO:0006281;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;DNA metabolic process#GO:0006259 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003704.3|UniProtKB=G3QMA5 G3QMA5 RNF222 PTHR47095:SF1 RING FINGER PROTEIN 222 RING FINGER PROTEIN 222 GORGO|Ensembl=ENSGGOG00000000359.3|UniProtKB=G3QDM9 G3QDM9 PPP2R5B PTHR10257:SF4 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT BETA ISOFORM phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;enzyme activator activity#GO:0008047 sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle process#GO:0022402 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PP2A#P00547;Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629 GORGO|Ensembl=ENSGGOG00000024266.2|UniProtKB=G3SJE0 G3SJE0 SLC7A5 PTHR11785:SF315 AMINO ACID TRANSPORTER LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 1 neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000039281.1|UniProtKB=A0A2I2ZI17 A0A2I2ZI17 PTHR19433:SF86 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 26-2 response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000012059.3|UniProtKB=G3R8Q0 G3R8Q0 HSF2BP PTHR15434:SF2 HEAT SHOCK FACTOR 2-BINDING PROTEIN HEAT SHOCK FACTOR 2-BINDING PROTEIN GORGO|Ensembl=ENSGGOG00000025587.2|UniProtKB=G3SJB2 G3SJB2 PTHR24040:SF3 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN SEX HORMONE-BINDING GLOBULIN binding#GO:0005488;hormone binding#GO:0042562;lipid binding#GO:0008289;steroid binding#GO:0005496 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002632.3|UniProtKB=G3QJJ7 G3QJJ7 MCUR1 PTHR14360:SF11 PROTEIN FMP32, MITOCHONDRIAL MITOCHONDRIAL CALCIUM UNIPORTER REGULATOR 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 mitochondrial calcium ion homeostasis#GO:0051560;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000037332.1|UniProtKB=A0A2I2Z2Y8 A0A2I2Z2Y8 RBFOX2 PTHR15597:SF31 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 2 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;nervous system development#GO:0007399 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000002423.3|UniProtKB=A0A2I2YAW4 A0A2I2YAW4 CEP41 PTHR44390:SF1 CENTROSOMAL PROTEIN OF 41 KDA CENTROSOMAL PROTEIN OF 41 KDA cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000005793.3|UniProtKB=G3QSN0 G3QSN0 VSIG2 PTHR45046:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000005038.3|UniProtKB=G3S2G5 G3S2G5 KIRREL3 PTHR11640:SF49 NEPHRIN KIN OF IRRE-LIKE PROTEIN 3 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cell adhesion#GO:0007155;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000010864.3|UniProtKB=G3RUJ6 G3RUJ6 MIGA2 PTHR21508:SF4 MITOGUARDIN MITOGUARDIN 2 cellular component organization#GO:0016043;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005 GORGO|Ensembl=ENSGGOG00000003767.3|UniProtKB=A0A2I2YMU5 A0A2I2YMU5 THOC5 PTHR13375:SF3 FMS INTERACTING PROTEIN THO COMPLEX SUBUNIT 5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 transport#GO:0006810;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000000850.3|UniProtKB=G3QEY2 G3QEY2 DERL3 PTHR11009:SF4 DER1-LIKE PROTEIN, DERLIN DERLIN-3 biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000004199.3|UniProtKB=G3QNL9 G3QNL9 FLNA PTHR38537:SF5 JITTERBUG, ISOFORM N FILAMIN-A Integrin signalling pathway#P00034>Filamin#P00914;Nicotine pharmacodynamics pathway#P06587>FLNA#P06601;Dopamine receptor mediated signaling pathway#P05912>FLNA#P05959 GORGO|Ensembl=ENSGGOG00000001331.3|UniProtKB=G3QG63 G3QG63 CATSPERZ PTHR42155:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT ZETA CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT ZETA cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;male gamete generation#GO:0048232;developmental maturation#GO:0021700;sperm capacitation#GO:0048240;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;cell maturation#GO:0048469;microtubule-based process#GO:0007017;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;sperm motility#GO:0097722;anatomical structure maturation#GO:0071695;microtubule-based movement#GO:0007018;cell motility#GO:0048870;gamete generation#GO:0007276;cell differentiation#GO:0030154;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;sexual reproduction#GO:0019953;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285;multicellular organismal reproductive process#GO:0048609 transporter complex#GO:1990351;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;monoatomic ion channel complex#GO:0034702;sperm flagellum#GO:0036126;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;sperm principal piece#GO:0097228;plasma membrane protein complex#GO:0098797 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000009182.3|UniProtKB=G3R1B4 G3R1B4 PLAUR PTHR10624:SF6 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR-RELATED UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Plasminogen activating cascade#P00050>uPAR#P01256;Blood coagulation#P00011>uPAR#P00433 GORGO|Ensembl=ENSGGOG00000011791.3|UniProtKB=G3R806 G3R806 AHCYL1 PTHR23420:SF3 ADENOSYLHOMOCYSTEINASE S-ADENOSYLHOMOCYSTEINE HYDROLASE-LIKE PROTEIN 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000004883.3|UniProtKB=G3QQC1 G3QQC1 ASPA PTHR15162:SF9 ASPARTOACYLASE ASPARTOACYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011098.3|UniProtKB=G3R694 G3R694 MED13L PTHR48249:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13-LIKE transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000003138.3|UniProtKB=A0A2I2ZHI6 A0A2I2ZHI6 MARCHF10 PTHR14471:SF5 MARCH7/10 E3 UBIQUITIN PROTEIN LIGASE FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF10-RELATED ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000003642.3|UniProtKB=G3QM61 G3QM61 MTHFD1L PTHR48099:SF12 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED MONOFUNCTIONAL C1-TETRAHYDROFOLATE SYNTHASE, MITOCHONDRIAL ligase activity, forming carbon-nitrogen bonds#GO:0016879;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;ligase activity#GO:0016874;catalytic activity#GO:0003824 small molecule biosynthetic process#GO:0044283;tetrahydrofolate biosynthetic process#GO:0046654;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 GORGO|Ensembl=ENSGGOG00000010216.3|UniProtKB=A0A2I2YYA5 A0A2I2YYA5 GAP43 PTHR10699:SF15 NEUROMODULIN NEUROMODULIN phospholipid binding#GO:0005543;carbohydrate derivative binding#GO:0097367;calmodulin binding#GO:0005516;phosphatidylinositol phosphate binding#GO:1901981;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;protein binding#GO:0005515;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 neuron projection development#GO:0031175;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regeneration#GO:0031099;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;tissue regeneration#GO:0042246;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;developmental growth#GO:0048589;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell recognition#GO:0008037;anatomical structure development#GO:0048856;system development#GO:0048731 postsynaptic density#GO:0014069;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000027849.2|UniProtKB=G3SG96 G3SG96 SRPRB PTHR11485:SF34 TRANSFERRIN SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT BETA protein targeting to ER#GO:0045047;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of protein localization#GO:0045184 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;rough endoplasmic reticulum#GO:0005791;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000004803.3|UniProtKB=G3QQ50 G3QQ50 PRELID3B PTHR11158:SF22 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING PROTEIN 3B lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 establishment of localization#GO:0051234;localization#GO:0051179;lipid localization#GO:0010876;transport#GO:0006810;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000010995.3|UniProtKB=G3R5Y0 G3R5Y0 SLC35D3 PTHR11132:SF515 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER D3 antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000009809.3|UniProtKB=G3R2X1 G3R2X1 F11 PTHR24253:SF44 TRANSMEMBRANE PROTEASE SERINE COAGULATION FACTOR XI catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;negative regulation of blood coagulation#GO:0030195;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of coagulation#GO:0050818;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of wound healing#GO:0061045;plasminogen activation#GO:0031639;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;regulation of hemostasis#GO:1900046;negative regulation of coagulation#GO:0050819;regulation of biological quality#GO:0065008;proteolysis#GO:0006508;negative regulation of hemostasis#GO:1900047;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;regulation of wound healing#GO:0061041;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;zymogen activation#GO:0031638;negative regulation of response to wounding#GO:1903035;metabolic process#GO:0008152;gene expression#GO:0010467;regulation of response to external stimulus#GO:0032101;protein maturation#GO:0051604;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;regulation of response to wounding#GO:1903034;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 Blood coagulation#P00011>FXIa#P00434;Blood coagulation#P00011>FXI#P00460 GORGO|Ensembl=ENSGGOG00000038151.1|UniProtKB=A0A2I2YLD8 A0A2I2YLD8 PTHR25952:SF255 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN GORGO|Ensembl=ENSGGOG00000043862.1|UniProtKB=G3S6T5 G3S6T5 LOC101132032 PTHR23262:SF183 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-11-RELATED multicellular organismal process#GO:0032501 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000036223.1|UniProtKB=A0A2I2ZXG7 A0A2I2ZXG7 PTHR23267:SF506 IMMUNOGLOBULIN LIGHT CHAIN NON-FUNCTIONAL IMMUNOGLOBULIN LAMBDA VARIABLE 11-55-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000005343.3|UniProtKB=G3QRH7 G3QRH7 RSRP1 PTHR47622:SF1 ARGININE/SERINE-RICH PROTEIN 1 ARGININE_SERINE-RICH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000015011.2|UniProtKB=G3RGA2 G3RGA2 MC4R PTHR22750:SF6 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 4 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000002085.3|UniProtKB=G3QI52 G3QI52 NXF3 PTHR10662:SF12 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 3 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleocytoplasmic transport#GO:0006913;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005426.3|UniProtKB=G3QRP9 G3QRP9 PARS2 PTHR42753:SF10 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER PROLINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000026328.2|UniProtKB=G3SFK4 G3SFK4 PTHR47081:SF1 FAMILY NOT NAMED ARMADILLO REPEAT-CONTAINING X-LINKED PROTEIN 4 GORGO|Ensembl=ENSGGOG00000009545.3|UniProtKB=A0A2I2ZX11 A0A2I2ZX11 RETN PTHR21101:SF11 RESISTIN RESISTIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 developmental process#GO:0032502;response to oxygen-containing compound#GO:1901700;cellular developmental process#GO:0048869;response to nitrogen compound#GO:1901698;response to endogenous stimulus#GO:0009719;fat cell differentiation#GO:0045444;response to hormone#GO:0009725;response to insulin#GO:0032868;cellular process#GO:0009987;cell differentiation#GO:0030154;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to peptide hormone#GO:0043434 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014557.3|UniProtKB=G3RF41 G3RF41 MTHFSD PTHR13017:SF0 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE-RELATED METHENYLTETRAHYDROFOLATE SYNTHASE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 GORGO|Ensembl=ENSGGOG00000003159.3|UniProtKB=G3QKW9 G3QKW9 KLHL41 PTHR24412:SF146 KELCH PROTEIN KELCH-LIKE PROTEIN 41 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of developmental process#GO:0050793;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of cell population proliferation#GO:0042127;protein metabolic process#GO:0019538;cellular process#GO:0009987;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;regulation of cell differentiation#GO:0045595;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;endomembrane system#GO:0012505;transferase complex#GO:1990234;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;A band#GO:0031672;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;sarcoplasm#GO:0016528;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;contractile muscle fiber#GO:0043292;sarcoplasmic reticulum#GO:0016529;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;sarcoplasmic reticulum membrane#GO:0033017;supramolecular complex#GO:0099080;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;Cul3-RING ubiquitin ligase complex#GO:0031463;sarcomere#GO:0030017;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle#GO:0043229;M band#GO:0031430;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;ubiquitin ligase complex#GO:0000151;myofibril#GO:0030016 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000036811.1|UniProtKB=G3S675 G3S675 PTHR23239:SF396 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 17 structural molecule activity#GO:0005198 cellular process#GO:0009987;organelle organization#GO:0006996;skin development#GO:0043588;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;developmental process#GO:0032502;epidermis development#GO:0008544;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000014852.3|UniProtKB=G3RFV9 G3RFV9 GRSF1 PTHR13976:SF42 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED G-RICH SEQUENCE FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000002164.3|UniProtKB=A0A2I2ZC11 A0A2I2ZC11 CSDE1 PTHR12913:SF1 UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN COLD SHOCK DOMAIN-CONTAINING PROTEIN E1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517 positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000009246.3|UniProtKB=G3R1G8 G3R1G8 PHLDB3 PTHR12156:SF22 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 3 GORGO|Ensembl=ENSGGOG00000016163.3|UniProtKB=G3RJ87 G3RJ87 GNRHR PTHR24241:SF22 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GONADOTROPIN-RELEASING HORMONE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>GnRHR#P06727;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Gonadotropin-releasing hormone receptor pathway#P06664>GnRHR#G06676;Gonadotropin-releasing hormone receptor pathway#P06664>GnRHR#G06892 GORGO|Ensembl=ENSGGOG00000028053.2|UniProtKB=A0A2I2ZVC6 A0A2I2ZVC6 KIRREL2 PTHR11640:SF51 NEPHRIN KIN OF IRRE-LIKE PROTEIN 2 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000026140.2|UniProtKB=G3RYN9 G3RYN9 PTHR23023:SF131 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016559.3|UniProtKB=G3RK92 G3RK92 IRF2 PTHR11949:SF22 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000009297.3|UniProtKB=G3R1K4 G3R1K4 SLC50A1 PTHR10791:SF30 RAG1-ACTIVATING PROTEIN 1 SUGAR TRANSPORTER SWEET1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013478.3|UniProtKB=G3RCC7 G3RCC7 TGM4 PTHR11590:SF70 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 4 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000008233.3|UniProtKB=G3RST8 G3RST8 ATE1 PTHR21367:SF1 ARGININE-TRNA-PROTEIN TRANSFERASE 1 ARGINYL-TRNA--PROTEIN TRANSFERASE 1 acyltransferase activity#GO:0016746;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on RNA#GO:0140098 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000003066.3|UniProtKB=B3Y615 B3Y615 TLR2 PTHR24365:SF17 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 2 signaling receptor activity#GO:0038023;lipid binding#GO:0008289;molecular transducer activity#GO:0060089;binding#GO:0005488 regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR1,2,6#P01380;Toll receptor signaling pathway#P00054>TLR#P01346 GORGO|Ensembl=ENSGGOG00000011996.3|UniProtKB=G3R8J6 G3R8J6 CRIM1 PTHR46439:SF1 CYSTEINE-RICH MOTOR NEURON 1 PROTEIN CYSTEINE-RICH MOTOR NEURON 1 PROTEIN GORGO|Ensembl=ENSGGOG00000013000.3|UniProtKB=G3S3B8 G3S3B8 TMEM263 PTHR31443:SF0 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 263 GORGO|Gene=ADGRG1|UniProtKB=Q50DM6 Q50DM6 ADGRG1 PTHR12011:SF318 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G1 transmembrane signaling receptor activity#GO:0004888;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;molecular transducer activity#GO:0060089;heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000010367.3|UniProtKB=G3R4C1 G3R4C1 UEVLD PTHR23306:SF18 TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 3 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 transport#GO:0006810;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000014133.4|UniProtKB=G3RE27 G3RE27 ANO10 PTHR12308:SF40 ANOCTAMIN ANOCTAMIN-10 molecular carrier activity#GO:0140104;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;intramembrane lipid carrier activity#GO:0140303;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;monoatomic anion transport#GO:0006820;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;monoatomic anion transmembrane transport#GO:0098656;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011018.3|UniProtKB=G3R604 G3R604 PLD3 PTHR10185:SF16 PHOSPHOLIPASE D - RELATED 5'-3' EXONUCLEASE PLD3 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000009285.3|UniProtKB=G3R1J7 G3R1J7 GALNT15 PTHR11675:SF36 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 15 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000004082.3|UniProtKB=A0A2I2YGV1 A0A2I2YGV1 CD109 PTHR11412:SF136 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000014042.3|UniProtKB=G3RDT4 G3RDT4 TNFAIP8L2 PTHR12757:SF4 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 2 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of response to stimulus#GO:0048585;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cell activation#GO:0050866;negative regulation of multicellular organismal process#GO:0051241;regulation of cell communication#GO:0010646;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;negative regulation of T cell activation#GO:0050868;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;regulation of T cell activation#GO:0050863;regulation of response to external stimulus#GO:0032101;negative regulation of cell-cell adhesion#GO:0022408;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of lymphocyte activation#GO:0051249;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002005.3|UniProtKB=G3QHY6 G3QHY6 LOC101146902 PTHR14224:SF28 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 10-RELATED ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000004513.3|UniProtKB=G3QPD4 G3QPD4 MEX3A PTHR23285:SF2 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3A RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005083.3|UniProtKB=G3QQW0 G3QQW0 USP2 PTHR21646:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of protein stability#GO:0031647;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000013826.3|UniProtKB=G3RD90 G3RD90 FAM81B PTHR22420:SF5 PROTEIN FAM81A PROTEIN FAM81B GORGO|Ensembl=ENSGGOG00000014539.3|UniProtKB=G3RF25 G3RF25 AJUBA PTHR24219:SF7 LIM DOMAIN-CONTAINING PROTEIN JUB LIM DOMAIN-CONTAINING PROTEIN AJUBA transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;regulation of hippo signaling#GO:0035330;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of hippo signaling#GO:0035331;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of translation#GO:0017148;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;P-body#GO:0000932;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;cell junction#GO:0030054;adherens junction#GO:0005912;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell-cell junction#GO:0005911;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000009517.3|UniProtKB=G3RTB6 G3RTB6 TGFBI PTHR10900:SF82 PERIOSTIN-RELATED TRANSFORMING GROWTH FACTOR-BETA-INDUCED PROTEIN IG-H3 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell adhesion#GO:0007155;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000001404.3|UniProtKB=G3QGD2 G3QGD2 CDK4 PTHR24056:SF129 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000040108.1|UniProtKB=A0A2I2YNS8 A0A2I2YNS8 RRM2 PTHR23409:SF20 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;reductase#PC00198 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909;p53 pathway#P00059>R2#G04692;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915 GORGO|Ensembl=ENSGGOG00000043009.1|UniProtKB=A0A2I2YF44 A0A2I2YF44 CIROP PTHR10942:SF6 LEISHMANOLYSIN-LIKE PEPTIDASE CILIATED LEFT-RIGHT ORGANIZER METALLOPEPTIDASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000012182.3|UniProtKB=G3R910 G3R910 DNAJC4 PTHR44825:SF1 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY C MEMBER 4 GORGO|Ensembl=ENSGGOG00000002956.3|UniProtKB=G3QKD3 G3QKD3 CBR1 PTHR43963:SF2 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE [NADPH] 1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000000728.3|UniProtKB=G3QEL9 G3QEL9 NRM PTHR31040:SF1 NURIM NURIM intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967 GORGO|Ensembl=ENSGGOG00000004573.3|UniProtKB=A0A2I2Y7F7 A0A2I2Y7F7 CIDEA PTHR12306:SF8 CELL DEATH ACTIVATOR CIDE LIPID TRANSFERASE CIDEA molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;lipid transfer activity#GO:0120013 cellular component organization or biogenesis#GO:0071840;lipid droplet organization#GO:0034389;organelle fusion#GO:0048284;organelle organization#GO:0006996;cellular component organization#GO:0016043;programmed cell death#GO:0012501;lipid storage#GO:0019915;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987 membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008192.3|UniProtKB=G3RZ60 G3RZ60 MRE11 PTHR10139:SF4 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle G2/M phase transition#GO:1902750;organelle organization#GO:0006996;meiotic DNA double-strand break formation#GO:0042138;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;biological regulation#GO:0065007;sexual reproduction#GO:0019953;regulation of G2/M transition of mitotic cell cycle#GO:0010389;telomere organization#GO:0032200;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;DNA recombination#GO:0006310;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;response to stress#GO:0006950;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;signaling#GO:0023052;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;double-strand break repair via nonhomologous end joining#GO:0006303;telomere maintenance#GO:0000723;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861 GORGO|Ensembl=ENSGGOG00000012557.3|UniProtKB=G3R9Z6 G3R9Z6 TMEM258 PTHR13636:SF0 TRANSMEMBRANE PROTEIN 258 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT TMEM258 binding#GO:0005488;protein-containing complex binding#GO:0044877 cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to endoplasmic reticulum stress#GO:0034976;response to stress#GO:0006950;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 GORGO|Ensembl=ENSGGOG00000040574.1|UniProtKB=A0A2I2ZAM9 A0A2I2ZAM9 PTHR43176:SF13 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED 3-HYDROXYISOBUTYRYL-COA HYDROLASE fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;deacylase activity#GO:0160215;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000008047.3|UniProtKB=A0A2I2YLX7 A0A2I2YLX7 XRN1 PTHR12341:SF7 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;binding#GO:0005488;nucleic acid binding#GO:0003676;exonuclease activity#GO:0004527;RNA binding#GO:0003723;hydrolase activity#GO:0016787;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518 mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 exoribonuclease#PC00099;RNA metabolism protein#PC00031 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 GORGO|Ensembl=ENSGGOG00000004332.3|UniProtKB=G3QNX2 G3QNX2 C11H2orf80 PTHR36296:SF1 GAMMA-CRYSTALLIN A CHROMOSOME 15 C2ORF80 HOMOLOG structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000025845.2|UniProtKB=G3RRS4 G3RRS4 RTN4 PTHR45799:SF1 RETICULON-LIKE PROTEIN RETICULON-4 cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endoplasmic reticulum tubular network organization#GO:0071786;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;cellular component organization#GO:0016043 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000012546.3|UniProtKB=A0A2I2Y2Y5 A0A2I2Y2Y5 RBFOX3 PTHR15597:SF25 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;multicellular organism development#GO:0007275;developmental process#GO:0032502;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;multicellular organismal process#GO:0032501;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000001852.3|UniProtKB=A0A2I2YVN4 A0A2I2YVN4 MYH9 PTHR45615:SF16 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-9 microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000014565.3|UniProtKB=G3SFX9 G3SFX9 PTHR13009:SF4 HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1 ACTIVATOR OF 90 KDA HEAT SHOCK PROTEIN ATPASE HOMOLOG 2-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000022496.2|UniProtKB=G3S6V9 G3S6V9 MAPRE1 PTHR10623:SF20 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 chromosome segregation#GO:0007059;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;cell cycle#GO:0007049;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule end#GO:1990752;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000006815.3|UniProtKB=G3QVA3 G3QVA3 SMAGP PTHR47394:SF1 SMALL CELL ADHESION GLYCOPROTEIN SMALL CELL ADHESION GLYCOPROTEIN GORGO|Ensembl=ENSGGOG00000000382.3|UniProtKB=G3QDQ1 G3QDQ1 SLC6A1 PTHR11616:SF138 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1 amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;amino acid transmembrane transporter activity#GO:0015171 sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;amino acid transport#GO:0006865;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;axon#GO:0030424 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000025827.2|UniProtKB=G3SHH2 G3SHH2 HNRNPA1L2 PTHR48026:SF2 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000001081.3|UniProtKB=G3QFJ2 G3QFJ2 FBXO22 PTHR14939:SF10 F-BOX ONLY PROTEIN 22 F-BOX ONLY PROTEIN 22 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of cell development#GO:0060284;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of cell differentiation#GO:0045595;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000002656.3|UniProtKB=A0A2I2YG21 A0A2I2YG21 PLEKHG4B PTHR45845:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 4B guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000002047.3|UniProtKB=A0A2I2Y2B0 A0A2I2Y2B0 TSPEAR PTHR15261:SF4 THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000027045.2|UniProtKB=G3RN33 G3RN33 TMC7 PTHR23302:SF42 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 7 channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;passive transmembrane transporter activity#GO:0022803 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000014902.3|UniProtKB=G3RG11 G3RG11 FNDC1 PTHR23197:SF8 TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1 molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 skeletal muscle tissue development#GO:0007519;tissue development#GO:0009888;muscle structure development#GO:0061061;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000023240.2|UniProtKB=G3SEL2 G3SEL2 UPK3BL1 PTHR15446:SF2 UROPLAKIN III UROPLAKIN-3B-LIKE PROTEIN 1-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000039324.1|UniProtKB=G3S482 G3S482 LOC101137094 PTHR23262:SF32 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-2-RELATED structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000005641.3|UniProtKB=A0A2I2ZFH2 A0A2I2ZFH2 PTHR21345:SF8 SPIRE PROTEIN SPIRE HOMOLOG 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 establishment of spindle localization#GO:0051293;membrane organization#GO:0061024;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;meiotic nuclear division#GO:0140013;actin filament organization#GO:0007015;cell cycle#GO:0007049;cell division#GO:0051301;actin cytoskeleton organization#GO:0030036;reproductive process#GO:0022414;organelle localization#GO:0051640;actin filament-based process#GO:0030029;sexual reproduction#GO:0019953;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;multicellular organismal reproductive process#GO:0048609;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;meiotic cell cycle#GO:0051321;Golgi vesicle transport#GO:0048193;membrane invagination#GO:0010324;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;gamete generation#GO:0007276;establishment of organelle localization#GO:0051656;cytokinesis#GO:0000910;nuclear division#GO:0000280;cytokinetic process#GO:0032506;cellular localization#GO:0051641;spindle localization#GO:0051653;cytoskeleton-dependent cytokinesis#GO:0061640 vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000016219.3|UniProtKB=G3SAE0 G3SAE0 LOC101136978 PTHR31543:SF3 DYNEIN REGULATORY COMPLEX SUBUNIT 4 DYNEIN REGULATORY COMPLEX SUBUNIT 4 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;positive regulation of signaling#GO:0023056;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;regulation of signaling#GO:0023051;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;sperm motility#GO:0097722;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of response to stimulus#GO:0048583;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;regulation of cell communication#GO:0010646;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of signal transduction#GO:0009967 motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;microtubule#GO:0005874;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;Golgi apparatus#GO:0005794;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000006487.3|UniProtKB=G3QUE3 G3QUE3 TRBV7-3 PTHR23268:SF105 T-CELL RECEPTOR BETA CHAIN NON-FUNCTIONAL T CELL RECEPTOR BETA VARIABLE 7-3-RELATED signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000036804.1|UniProtKB=A0A2I2YVM6 A0A2I2YVM6 PTHR46880:SF6 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 385C GORGO|Ensembl=ENSGGOG00000039865.1|UniProtKB=A0A2I2ZGJ9 A0A2I2ZGJ9 PTHR10807:SF117 MYOTUBULARIN-RELATED SET BINDING FACTOR 1 molecular function regulator activity#GO:0098772;phosphoric ester hydrolase activity#GO:0042578;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;guanyl-nucleotide exchange factor activity#GO:0005085 glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;lipid modification#GO:0030258;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000005558.3|UniProtKB=G3QS24 G3QS24 HOOK2 PTHR18947:SF37 HOOK PROTEINS PROTEIN HOOK HOMOLOG 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cytoplasmic microtubule organization#GO:0031122;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization#GO:0051179;supramolecular fiber organization#GO:0097435 intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005458.3|UniProtKB=G3QRT4 G3QRT4 DHX58 PTHR14074:SF7 HELICASE WITH DEATH DOMAIN-RELATED ATP-DEPENDENT RNA HELICASE DHX58 cation binding#GO:0043169;metal ion binding#GO:0046872;RNA binding#GO:0003723;transition metal ion binding#GO:0046914;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;ion binding#GO:0043167;single-stranded RNA binding#GO:0003727;zinc ion binding#GO:0008270 response to external biotic stimulus#GO:0043207;intracellular receptor signaling pathway#GO:0030522;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;antiviral innate immune response#GO:0140374;innate immune response-activating signaling pathway#GO:0002758;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to virus#GO:0009615;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;negative regulation of cell communication#GO:0010648;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of signal transduction#GO:0009968;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000026943.2|UniProtKB=G3QJ45 G3QJ45 TMEFF1 PTHR21632:SF3 REGULATORY PROTEIN ZESTE TOMOREGULIN-1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000002347.3|UniProtKB=G3QIU1 G3QIU1 PTHR47109:SF1 NUCLEOREDOXIN-LIKE PROTEIN 1 NUCLEOREDOXIN-LIKE PROTEIN 1 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000004853.3|UniProtKB=G3QQ96 G3QQ96 HTRA1 PTHR22939:SF13 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cell death#GO:0008219;protein metabolic process#GO:0019538;proteolysis#GO:0006508 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000016929.3|UniProtKB=G3RL84 G3RL84 AGBL5 PTHR12756:SF12 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE-LIKE PROTEIN 5 metallocarboxypeptidase activity#GO:0004181;protein binding#GO:0005515;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;binding#GO:0005488;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;metalloexopeptidase activity#GO:0008235;tubulin binding#GO:0015631 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000007393.3|UniProtKB=G3SK36 G3SK36 ENPEP PTHR11533:SF276 PROTEASE M1 ZINC METALLOPROTEASE GLUTAMYL AMINOPEPTIDASE metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 peptide metabolic process#GO:0006518;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;proteolysis#GO:0006508;circulatory system process#GO:0003013;catabolic process#GO:0009056;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;system process#GO:0003008;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;biological regulation#GO:0065007;blood circulation#GO:0008015;hormone metabolic process#GO:0042445;multicellular organismal process#GO:0032501;gene expression#GO:0010467;protein maturation#GO:0051604;peptide catabolic process#GO:0043171;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;protein processing#GO:0016485;cellular process#GO:0009987;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000037634.1|UniProtKB=A0A2I2ZVR2 A0A2I2ZVR2 PTHR11599:SF16 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-2 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 proteasome complex#GO:0000502;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;peptidase complex#GO:1905368 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000037106.1|UniProtKB=A0A2I2YMS6 A0A2I2YMS6 PTHR23267:SF320 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000014604.3|UniProtKB=G3RSE9 G3RSE9 PRR3 PTHR47398:SF1 PROLINE-RICH PROTEIN 3 PROLINE-RICH PROTEIN 3 protein phosphatase inhibitor activity#GO:0004864;molecular adaptor activity#GO:0060090;enzyme inhibitor activity#GO:0004857;enzyme-substrate adaptor activity#GO:0140767;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;protein-macromolecule adaptor activity#GO:0030674;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678 positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein-containing complex disassembly#GO:0043244;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular component organization#GO:0051130 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000025974.2|UniProtKB=G3R131 G3R131 PTHR12039:SF13 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 nucleotidyltransferase#PC00174;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000003347.3|UniProtKB=A0A2I2Y8V8 A0A2I2Y8V8 IL15RA PTHR15060:SF0 INTERLEUKIN-15 RECEPTOR SUBUNIT ALPHA INTERLEUKIN-15 RECEPTOR SUBUNIT ALPHA transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 response to cytokine#GO:0034097;response to chemical#GO:0042221;interleukin-15-mediated signaling pathway#GO:0035723;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000001657.3|UniProtKB=G3QH15 G3QH15 RGS13 PTHR10845:SF32 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 13 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 GORGO|Ensembl=ENSGGOG00000015995.3|UniProtKB=G3S1V6 G3S1V6 IL36B PTHR10078:SF24 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-36 BETA molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 positive regulation of lymphocyte activation#GO:0051251;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;defense response#GO:0006952;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;regulation of cell adhesion#GO:0030155;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;positive regulation of multicellular organismal process#GO:0051240;response to lipopolysaccharide#GO:0032496;positive regulation of cell differentiation#GO:0045597;positive regulation of cell development#GO:0010720;cellular response to lipid#GO:0071396;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;regulation of hemopoiesis#GO:1903706;inflammatory response#GO:0006954;response to bacterium#GO:0009617;regulation of developmental process#GO:0050793;response to external biotic stimulus#GO:0043207;positive regulation of cell adhesion#GO:0045785;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;regulation of leukocyte cell-cell adhesion#GO:1903037;response to other organism#GO:0051707;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;regulation of multicellular organismal development#GO:2000026;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;positive regulation of leukocyte activation#GO:0002696;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;response to chemical#GO:0042221;positive regulation of T cell activation#GO:0050870;response to cytokine#GO:0034097;regulation of T cell activation#GO:0050863;response to lipid#GO:0033993;positive regulation of cell-cell adhesion#GO:0022409;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;interleukin superfamily#PC00128;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000002023.3|UniProtKB=G3QI02 G3QI02 AEBP2 PTHR46541:SF1 ZINC FINGER PROTEIN AEBP2 ZINC FINGER PROTEIN AEBP2 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000027864.2|UniProtKB=G3SFH6 G3SFH6 PTHR24379:SF136 KRAB AND ZINC FINGER DOMAIN-CONTAINING TRANSCRIPTION FACTOR E4F1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000004917.3|UniProtKB=A0A2I2YLS0 A0A2I2YLS0 PTHR14454:SF5 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 2 GORGO|Ensembl=ENSGGOG00000038749.1|UniProtKB=A0A2I2ZW17 A0A2I2ZW17 PTHR11183:SF125 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN GLUCOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycogen biosynthetic process#GO:0005978;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;glycogen metabolic process#GO:0005977;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;energy reserve metabolic process#GO:0006112;polysaccharide biosynthetic process#GO:0000271;glucan biosynthetic process#GO:0009250 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000024367.2|UniProtKB=A0A2I2ZP76 A0A2I2ZP76 PTHR10351:SF56 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000001577.3|UniProtKB=G3RYY8 G3RYY8 ZNF496 PTHR23226:SF180 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 496 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004727.3|UniProtKB=A0A2I2Y3V7 A0A2I2Y3V7 ITGB3BP PTHR15581:SF0 CENTROMERE PROTEIN R CENTROMERE PROTEIN R membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000014534.3|UniProtKB=G3RF26 G3RF26 ASAH1 PTHR28583:SF1 ACID AMIDASE ACID CERAMIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000016557.3|UniProtKB=A0A2I2YQM3 A0A2I2YQM3 BAZ1B PTHR46802:SF1 TYROSINE-PROTEIN KINASE BAZ1B TYROSINE-PROTEIN KINASE BAZ1B catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;histone binding#GO:0042393;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;binding#GO:0005488 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular component organization#GO:0016043;response to stress#GO:0006950;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;non-receptor tyrosine protein kinase#PC00168 GORGO|Ensembl=ENSGGOG00000012516.3|UniProtKB=G3R9X1 G3R9X1 PTHR18866:SF130 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE PROPIONYL-COA CARBOXYLASE ALPHA CHAIN, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ligase#PC00142;metabolite interconversion enzyme#PC00262 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 GORGO|Ensembl=ENSGGOG00000008013.3|UniProtKB=G3RMZ3 G3RMZ3 DENND3 PTHR12296:SF32 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN 3 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular localization#GO:0051641;localization#GO:0051179;regulation of intracellular signal transduction#GO:1902531;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;regulation of signaling#GO:0023051;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;regulation of small GTPase mediated signal transduction#GO:0051056;intracellular transport#GO:0046907;transport#GO:0006810;regulation of response to stimulus#GO:0048583;vacuolar transport#GO:0007034 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000025526.2|UniProtKB=G3RQG4 G3RQG4 CDC20B PTHR19918:SF4 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG B protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;binding#GO:0005488;enzyme activator activity#GO:0008047 regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;proteasomal protein catabolic process#GO:0010498 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000008370.3|UniProtKB=G3QZ77 G3QZ77 PRSS58 PTHR24271:SF56 KALLIKREIN-RELATED SERINE PROTEASE 58 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;extracellular region#GO:0005576;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000014194.3|UniProtKB=G3RE71 G3RE71 PIGG PTHR23072:SF0 PHOSPHATIDYLINOSITOL GLYCAN-RELATED GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 2, CATALYTIC SUBUNIT catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000006089.3|UniProtKB=G3S3K3 G3S3K3 XPOT PTHR15952:SF12 EXPORTIN-T/LOS1 EXPORTIN-T nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907 organelle envelope#GO:0031967;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000039758.1|UniProtKB=G3RGI2 G3RGI2 HTR3C PTHR18945:SF931 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3C ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;establishment of localization#GO:0051234;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052 monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235;cation channel complex#GO:0034703 ligand-gated ion channel#PC00141 5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422 GORGO|Ensembl=ENSGGOG00000027087.2|UniProtKB=G3RRT7 G3RRT7 PTHR13036:SF2 BETA1,4 MANNOSYLTRANSFERASE GLYCOSYLTRANSFERASE ALG1L2-RELATED glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000005530.3|UniProtKB=G3QRZ9 G3QRZ9 PCDH20 PTHR24028:SF260 CADHERIN-87A PROTOCADHERIN-20 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000008801.3|UniProtKB=G3R0C3 G3R0C3 MARK4 PTHR24346:SF28 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP_MICROTUBULE AFFINITY-REGULATING KINASE 4 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000042474.1|UniProtKB=A0A2I2YTR3 A0A2I2YTR3 LOC109025084 PTHR12146:SF10 40S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN ES10 structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025860.2|UniProtKB=G3S8U4 G3S8U4 KCNJ10 PTHR11767:SF21 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000027234.2|UniProtKB=G3SFB3 G3SFB3 MVB12A PTHR31612:SF2 MULTIVESICULAR BODY SUBUNIT 12A MULTIVESICULAR BODY SUBUNIT 12A establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;vacuolar transport#GO:0007034;transport#GO:0006810;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular transport#GO:0046907;endosomal transport#GO:0016197;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;localization#GO:0051179;cellular localization#GO:0051641 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cytosol#GO:0005829;membrane#GO:0016020;ESCRT I complex#GO:0000813;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000005163.3|UniProtKB=G3QR26 G3QR26 GSDME PTHR15207:SF1 NONSYNDROMIC HEARING IMPAIRMENT PROTEIN GASDERMIN-E channel activity#GO:0015267;wide pore channel activity#GO:0022829;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 inflammatory response#GO:0006954;cell death#GO:0008219;cellular process#GO:0009987;programmed cell death#GO:0012501;response to stress#GO:0006950;defense response#GO:0006952;response to stimulus#GO:0050896 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004958.3|UniProtKB=A0A2I2YFM1 A0A2I2YFM1 MAGI1 PTHR10316:SF12 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of protein localization to membrane#GO:1905475;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879 adherens junction#GO:0005912;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;synapse#GO:0045202;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005067.3|UniProtKB=G3QQU3 G3QQU3 CASC3 PTHR13434:SF0 PROTEIN CASC3 PROTEIN CASC3 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 intracellular organelle#GO:0043229;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000000519.3|UniProtKB=G3SCU6 G3SCU6 GNAI3 PTHR10218:SF230 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-3 molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552 G-protein#PC00020;heterotrimeric G-protein#PC00117 Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Enkephalin release#P05913>G-Protein (i)#P05974;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;PI3 kinase pathway#P00048>Galpha#P01199;Endogenous cannabinoid signaling#P05730>Galpha#P05751;Opioid proenkephalin pathway#P05915>G-protein#P05994;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Nicotine pharmacodynamics pathway#P06587>GNAI#P06609;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828 GORGO|Ensembl=ENSGGOG00000002634.3|UniProtKB=G3QJJ5 G3QJJ5 HOXB6 PTHR45659:SF9 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B6 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000025759.2|UniProtKB=G3RT62 G3RT62 KBTBD12 PTHR24412:SF510 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 12 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003770.3|UniProtKB=G3QMG4 G3QMG4 ADPRS PTHR16222:SF24 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH3 catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;metabolic process#GO:0008152;cellular response to chemical stress#GO:0062197;macromolecule metabolic process#GO:0043170;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000040535.1|UniProtKB=A0A2I2Z9P5 A0A2I2Z9P5 PTHR23268:SF97 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 11-3 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000001744.3|UniProtKB=G3QH99 G3QH99 ASAP2 PTHR45854:SF4 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000012491.3|UniProtKB=G3R9U3 G3R9U3 ALDH18A1 PTHR11063:SF28 GLUTAMATE SEMIALDEHYDE DEHYDROGENASE DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000009758.3|UniProtKB=G3R2S2 G3R2S2 CNIH2 PTHR12290:SF13 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 2 synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;dendrite#GO:0030425;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;dendritic tree#GO:0097447;endomembrane system#GO:0012505;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;membrane#GO:0016020;neuron projection#GO:0043005;cell junction#GO:0030054;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000036346.1|UniProtKB=A0A2I2Y542 A0A2I2Y542 PTHR19367:SF35 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 40 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000004403.3|UniProtKB=G3QP31 G3QP31 ARHGAP40 PTHR14963:SF4 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 40 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological quality#GO:0065008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of actin filament length#GO:0030832;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;regulation of signal transduction#GO:0009966;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000028348.2|UniProtKB=A0A2I2Y5S3 A0A2I2Y5S3 LOC101146118 PTHR48018:SF5 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8A1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003282.3|UniProtKB=G3S0V2 G3S0V2 SMARCC2 PTHR12802:SF105 SWI/SNF COMPLEX-RELATED SWI_SNF COMPLEX SUBUNIT SMARCC2 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000002481.3|UniProtKB=G3QJ60 G3QJ60 GDE1 PTHR46320:SF1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;amine metabolic process#GO:0009308;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;small molecule metabolic process#GO:0044281 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000009510.3|UniProtKB=A0A2K5TIY3 A0A2K5TIY3 FSHB PTHR11515:SF17 GLYCOPROTEIN HORMONE BETA CHAIN FOLLITROPIN SUBUNIT BETA signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546 rhythmic process#GO:0048511;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal reproductive process#GO:0048609;reproductive system development#GO:0061458;female gonad development#GO:0008585;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;reproductive structure development#GO:0048608;reproductive process#GO:0022414;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;sex differentiation#GO:0007548;signal transduction#GO:0007165;gonad development#GO:0008406;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>3' FSHbeta#G06900;Gonadotropin-releasing hormone receptor pathway#P06664>5' FSHbeta#G06904;Gonadotropin-releasing hormone receptor pathway#P06664>FSHbeta#P06809;Gonadotropin-releasing hormone receptor pathway#P06664>FSHbeta#G06678 GORGO|Ensembl=ENSGGOG00000027027.2|UniProtKB=G3RN27 G3RN27 MED19 PTHR22536:SF1 LUNG CANCER METASTASIS-RELATED LCMR1 PROTEIN MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19 regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000039466.1|UniProtKB=A0A2I2ZVC1 A0A2I2ZVC1 PTHR12786:SF3 SPLICING FACTOR SF3A-RELATED SPLICING FACTOR 3A SUBUNIT 3 RNA binding#GO:0003723;binding#GO:0005488;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;U2 snRNP#GO:0005686;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000000649.3|UniProtKB=G3QEE6 G3QEE6 LRSAM1 PTHR48051:SF47 FAMILY NOT NAMED RING-TYPE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000005815.3|UniProtKB=G3QSQ1 G3QSQ1 GALNT17 PTHR11675:SF38 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 17 glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000012776.3|UniProtKB=G3RAK7 G3RAK7 PTHR11475:SF75 OXIDASE/PEROXIDASE PEROXIDASIN HOMOLOG oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;extracellular matrix assembly#GO:0085029;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;extracellular structure organization#GO:0043062 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006206.3|UniProtKB=A0A2I2YL68 A0A2I2YL68 PHF14 PTHR13793:SF150 PHD FINGER PROTEINS PHD FINGER PROTEIN 14 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000026936.2|UniProtKB=A0A2I2YI29 A0A2I2YI29 PTHR45850:SF6 SORTING NEXIN FAMILY MEMBER PX DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012262.4|UniProtKB=G3R993 G3R993 BANK1 PTHR16267:SF13 BANK1/PIK3AP1 FAMILY MEMBER B-CELL SCAFFOLD PROTEIN WITH ANKYRIN REPEATS protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102 B cell activation#GO:0042113;regulation of B cell activation#GO:0050864;cellular process#GO:0009987;lymphocyte activation#GO:0046649;regulation of multicellular organismal process#GO:0051239;negative regulation of lymphocyte activation#GO:0051250;negative regulation of signal transduction#GO:0009968;negative regulation of leukocyte activation#GO:0002695;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of lymphocyte activation#GO:0051249;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of cell activation#GO:0050866;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;cell activation#GO:0001775;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;leukocyte activation#GO:0045321;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646 GORGO|Ensembl=ENSGGOG00000027239.2|UniProtKB=Q0MQE6 Q0MQE6 NDUFB8 PTHR12840:SF2 NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000038039.1|UniProtKB=A0A2I2Z3N2 A0A2I2Z3N2 ZNF529 PTHR23226:SF412 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007924.3|UniProtKB=A0A2I2YHH0 A0A2I2YHH0 RBM34 PTHR23236:SF25 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H RNA-BINDING PROTEIN 34 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000005155.3|UniProtKB=G3QR17 G3QR17 ADPRH PTHR16222:SF26 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;metabolic process#GO:0008152;protein modification process#GO:0036211;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000013486.3|UniProtKB=A0A2I2Z951 A0A2I2Z951 FBXO15 PTHR46731:SF1 F-BOX ONLY PROTEIN 15 F-BOX ONLY PROTEIN 15 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 GORGO|Ensembl=ENSGGOG00000000911.3|UniProtKB=G3QF37 G3QF37 SHOC1 PTHR35668:SF1 PROTEIN SHORTAGE IN CHIASMATA 1 ORTHOLOG PROTEIN SHORTAGE IN CHIASMATA 1 ORTHOLOG DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697 organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;homologous recombination#GO:0035825;reproductive process#GO:0022414;cell cycle#GO:0007049;meiosis I#GO:0007127;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;resolution of meiotic recombination intermediates#GO:0000712;cellular process#GO:0009987 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013875.3|UniProtKB=G3RDD5 G3RDD5 FERMT2 PTHR16160:SF11 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 2 protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839 cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 GORGO|Ensembl=ENSGGOG00000003639.3|UniProtKB=A0A2I2YMB1 A0A2I2YMB1 LFNG PTHR10811:SF7 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE LUNATIC FRINGE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 transferase#PC00220;glycosyltransferase#PC00111 Notch signaling pathway#P00045>Fringe#P01107 GORGO|Ensembl=ENSGGOG00000039790.1|UniProtKB=A0A2I2ZLS9 A0A2I2ZLS9 PTHR11134:SF32 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER BETA-ADAPTIN APPENDAGE C-TERMINAL SUBDOMAIN DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;clathrin binding#GO:0030276;binding#GO:0005488 transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;endocytic vesicle#GO:0030139;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;plasma membrane#GO:0005886;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000002523.3|UniProtKB=G3QJ98 G3QJ98 LRRC23 PTHR15454:SF74 NISCHARIN RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 23 cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;protein-containing complex assembly#GO:0065003;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell projection organization#GO:0030030;reproductive process#GO:0022414;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;axoneme assembly#GO:0035082;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010046.3|UniProtKB=G3RRP2 G3RRP2 PGAM5 PTHR20935:SF0 PHOSPHOGLYCERATE MUTASE-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;biological regulation#GO:0065007;positive regulation of mitochondrial fission#GO:0090141;positive regulation of cellular component organization#GO:0051130;positive regulation of developmental process#GO:0051094;positive regulation of organelle organization#GO:0010638;regulation of anatomical structure morphogenesis#GO:0022603 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 mutase#PC00160;isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000002142.3|UniProtKB=G3S1U9 G3S1U9 CYFIP1 PTHR12195:SF4 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN 1 neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;lamellipodium assembly#GO:0030032;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;plasma membrane bounded cell projection assembly#GO:0120031;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;axon guidance#GO:0007411;regulation of metabolic process#GO:0019222;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;neuron projection#GO:0043005;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 GORGO|Ensembl=ENSGGOG00000042451.1|UniProtKB=A0A2I2ZM63 A0A2I2ZM63 PTHR10496:SF7 40S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN ES24 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016719.3|UniProtKB=A0A2I2Y2K5 A0A2I2Y2K5 PROCA1 PTHR12253:SF17 RH14732P PROTEIN PROCA1 GORGO|Ensembl=ENSGGOG00000002324.3|UniProtKB=G3QIS1 G3QIS1 RNF113A PTHR12930:SF2 ZINC FINGER PROTEIN 183 E3 UBIQUITIN-PROTEIN LIGASE RNF113A acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001941.3|UniProtKB=G3QHS6 G3QHS6 PTHR24381:SF427 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 491 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000025852.3|UniProtKB=G3S150 G3S150 IMPG1 PTHR12199:SF3 INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 1 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000011973.3|UniProtKB=G3R8G9 G3R8G9 LYRM7 PTHR46749:SF1 COMPLEX III ASSEMBLY FACTOR LYRM7 COMPLEX III ASSEMBLY FACTOR LYRM7 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000027093.2|UniProtKB=A0A2I2Y1M2 A0A2I2Y1M2 PTHR10410:SF31 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED LYS-63-SPECIFIC DEUBIQUITINASE metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000009853.3|UniProtKB=G3R308 G3R308 CDC26 PTHR28579:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT CDC26 ANAPHASE-PROMOTING COMPLEX SUBUNIT CDC26 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein K11-linked ubiquitination#GO:0070979;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346 nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003317.3|UniProtKB=G3QLB1 G3QLB1 OTOP2 PTHR21522:SF35 PROTON CHANNEL OTOP PROTON CHANNEL OTOP2 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000041035.1|UniProtKB=A0A2I2Y924 A0A2I2Y924 LOC134757035 PTHR15141:SF74 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN A2 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000006974.3|UniProtKB=G3QVP3 G3QVP3 HDHD3 PTHR46191:SF2 FAMILY NOT NAMED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000012505.3|UniProtKB=A0A2I2ZDY5 A0A2I2ZDY5 NPEPL1 PTHR11963:SF4 LEUCINE AMINOPEPTIDASE-RELATED AMINOPEPTIDASE NPEPL1-RELATED peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000005462.3|UniProtKB=G3QRT5 G3QRT5 NOP53 PTHR14211:SF8 GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2 RIBOSOME BIOGENESIS PROTEIN NOP53 nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843;RNA binding#GO:0003723 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000037966.1|UniProtKB=A0A2I2ZVB8 A0A2I2ZVB8 DDX49 PTHR24031:SF761 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX49-RELATED macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000001293.3|UniProtKB=G3RS93 G3RS93 LOC109023073 PTHR23262:SF133 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-6-RELATED structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000040946.1|UniProtKB=A0A2I2YQ65 A0A2I2YQ65 PTHR31545:SF4 SEEDY PROTEIN A/C FAMILY MEMBER SPEEDY PROTEIN A protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;cell cycle G1/S phase transition#GO:0044843;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of cell population proliferation#GO:0042127;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;positive regulation of cell population proliferation#GO:0008284;cell cycle#GO:0007049;regulation of biological process#GO:0050789;cell cycle process#GO:0022402 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000013204.3|UniProtKB=G3RBM1 G3RBM1 PTHR11467:SF181 HISTONE H1 HISTONE H1.9-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000005395.3|UniProtKB=G3QRM4 G3QRM4 R3HDML PTHR10334:SF62 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR R3HDML extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000258.3|UniProtKB=G3QDE1 G3QDE1 PTHR15653:SF2 STRIATIN STRIATIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of signal transduction#GO:0009966;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 neuron projection#GO:0043005;cell body#GO:0044297;postsynapse#GO:0098794;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202;dendritic tree#GO:0097447;dendrite#GO:0030425;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000006681.3|UniProtKB=G3RZE5 G3RZE5 MGAT4A PTHR12062:SF4 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004991.3|UniProtKB=G3QQM1 G3QQM1 PRRG4 PTHR24278:SF38 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 4 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000001639.3|UniProtKB=G3QGZ7 G3QGZ7 CAVIN2 PTHR15240:SF1 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 membrane microdomain#GO:0098857;intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853;cell periphery#GO:0071944;membrane#GO:0016020;membrane raft#GO:0045121;caveola#GO:0005901;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000026305.2|UniProtKB=A0A2I2YI30 A0A2I2YI30 LOC101150278 PTHR26450:SF121 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52A4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005672.3|UniProtKB=G3QSC8 G3QSC8 AIRE PTHR47025:SF30 AUTOIMMUNE REGULATOR AUTOIMMUNE REGULATOR protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;histone binding#GO:0042393 regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;regulation of biosynthetic process#GO:0009889;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;lymphocyte mediated immunity#GO:0002449;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;lymphocyte activation#GO:0046649;lymphocyte differentiation#GO:0030098;T cell mediated immunity#GO:0002456;cell activation#GO:0001775;regulation of lymphocyte migration#GO:2000401;system development#GO:0048731;regulation of cell motility#GO:2000145;tissue morphogenesis#GO:0048729;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;leukocyte activation#GO:0045321;regulation of leukocyte migration#GO:0002685;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;hemopoiesis#GO:0030097;adaptive immune response#GO:0002250;tissue development#GO:0009888;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of metabolic process#GO:0009893;leukocyte mediated immunity#GO:0002443;immune system development#GO:0002520;mononuclear cell differentiation#GO:1903131;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;cell differentiation#GO:0030154;immune effector process#GO:0002252;positive regulation of transcription by RNA polymerase II#GO:0045944;humoral immune response#GO:0006959;morphogenesis of an epithelium#GO:0002009;animal organ development#GO:0048513;T cell differentiation#GO:0030217 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000027776.2|UniProtKB=G3S1Z7 G3S1Z7 IRX5 PTHR11211:SF17 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000011499.3|UniProtKB=G3R787 G3R787 CLMN PTHR47535:SF7 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G CALMIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 organelle localization#GO:0051640;cellular localization#GO:0051641;regulation of cell population proliferation#GO:0042127;localization#GO:0051179;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;nuclear migration#GO:0007097;regulation of cellular process#GO:0050794;establishment of organelle localization#GO:0051656;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;transport#GO:0006810;establishment of localization#GO:0051234;negative regulation of cell population proliferation#GO:0008285;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane#GO:0016020;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000037483.1|UniProtKB=A0A2I2ZBF7 A0A2I2ZBF7 PTHR12612:SF46 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000015887.3|UniProtKB=A0A2I2ZYD1 A0A2I2ZYD1 CDKL1 PTHR24056:SF192 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000025669.2|UniProtKB=A0A2I2Y452 A0A2I2Y452 PTHR46131:SF6 SD08549P SOLUTE CARRIER FAMILY 25 MEMBER 51 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;purine nucleotide transmembrane transporter activity#GO:0015216;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000014623.3|UniProtKB=G3RS47 G3RS47 CLCA4 PTHR10579:SF2 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000024103.2|UniProtKB=A0A2I2Z6P1 A0A2I2Z6P1 PTHR14112:SF5 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX2-RELATED cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000009521.3|UniProtKB=A0A2I2ZRQ1 A0A2I2ZRQ1 GKN1 PTHR16483:SF1 GASTROKINE 1 GASTROKINE-1 biological regulation#GO:0065007;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000065.3|UniProtKB=A0A2I2ZV35 A0A2I2ZV35 TRAPPC6B PTHR12817:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907 Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;cis-Golgi network#GO:0005801;vesicle tethering complex#GO:0099023;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000006898.3|UniProtKB=A0A2I2Z8A3 A0A2I2Z8A3 ATP6V0E2 PTHR12263:SF2 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT E 2 proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000022390.2|UniProtKB=G3SBZ7 G3SBZ7 TNFRSF17 PTHR20437:SF0 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 13/17 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027595.2|UniProtKB=A0A2I2Y647 A0A2I2Y647 LOC101129376 PTHR10351:SF29 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 HOMOLOG 4 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000006018.3|UniProtKB=G3QT76 G3QT76 TNF PTHR11471:SF23 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;regulation of programmed cell death#GO:0043067;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;response to tumor necrosis factor#GO:0034612;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cytokine-mediated signaling pathway#GO:0019221;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Apoptosis signaling pathway#P00006>TNF#P00259 GORGO|Ensembl=ENSGGOG00000010465.3|UniProtKB=G3R4J7 G3R4J7 PRSS35 PTHR15462:SF17 SERINE PROTEASE INACTIVE SERINE PROTEASE 35 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000010613.3|UniProtKB=G3R4Y4 G3R4Y4 RETREG1 PTHR28659:SF3 RETICULON-LIKE PROTEIN RETICULOPHAGY REGULATOR 1 process utilizing autophagic mechanism#GO:0061919;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of neuron apoptotic process#GO:0043523;negative regulation of neuron apoptotic process#GO:0043524;reticulophagy#GO:0061709;negative regulation of programmed cell death#GO:0043069;autophagy#GO:0006914;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;macroautophagy#GO:0016236 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000001670.3|UniProtKB=G3QH28 G3QH28 PTHR22589:SF74 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, LIVER ISOFORM acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;carnitine metabolic process#GO:0009437;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000017069.3|UniProtKB=A0A2I2ZYJ1 A0A2I2ZYJ1 UIMC1 PTHR15932:SF2 UBIQUITIN INTERACTION MOTIF-CONTAINING PROTEIN 1 BRCA1-A COMPLEX SUBUNIT RAP80 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;cellular component organization#GO:0016043;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chromatin remodeling#GO:0006338;regulation of response to stress#GO:0080134;DNA repair#GO:0006281;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of DNA metabolic process#GO:0051054;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;site of double-strand break#GO:0035861;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;organelle lumen#GO:0043233;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000011855.3|UniProtKB=G3R867 G3R867 TTLL9 PTHR12241:SF39 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL9-RELATED ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000039917.1|UniProtKB=A0A2I2ZSW0 A0A2I2ZSW0 PTHR13049:SF7 DUF814-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 25 GORGO|Ensembl=ENSGGOG00000013706.3|UniProtKB=G3RCY0 G3RCY0 PDE3A PTHR11347:SF104 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE cyclic-nucleotide phosphodiesterase activity#GO:0004112;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000016931.3|UniProtKB=A0A2I2Z4A3 A0A2I2Z4A3 SSBP4 PTHR12610:SF30 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000001665.3|UniProtKB=G3SEF8 G3SEF8 ZC3H6 PTHR13119:SF22 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 6 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity#GO:0001217 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription elongation#GO:0032784;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000023678.2|UniProtKB=A0A2I2ZK97 A0A2I2ZK97 PTHR10913:SF13 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 1 cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 GORGO|Ensembl=ENSGGOG00000001658.3|UniProtKB=G3QH23 G3QH23 IGF2R PTHR15071:SF17 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR protein binding#GO:0005515;growth factor binding#GO:0019838;binding#GO:0005488 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to lysosome#GO:0061462;protein localization to organelle#GO:0033365;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;protein localization to vacuole#GO:0072665;lysosomal transport#GO:0007041;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179 Golgi apparatus#GO:0005794;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;endomembrane system#GO:0012505;late endosome#GO:0005770;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Apoptosis signaling pathway#P00006>IGFR2#P00282;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895 GORGO|Ensembl=ENSGGOG00000037806.1|UniProtKB=G3SEP4 G3SEP4 LOC109027020 PTHR10666:SF438 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN ES31 FUSION PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;nucleus#GO:0005634;ribosome#GO:0005840;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001587.3|UniProtKB=G3QGV0 G3QGV0 CYLC1 PTHR16742:SF1 CYCLICIN CYLICIN-1 vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000008309.3|UniProtKB=G3QZ24 G3QZ24 PTHR47958:SF215 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX17-RELATED mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000013179.3|UniProtKB=G3RBK2 G3RBK2 DPYSL4 PTHR11647:SF55 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;dihydropyrimidinase activity#GO:0004157;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812 nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;pyrimidine nucleobase metabolic process#GO:0006206;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339 GORGO|Ensembl=ENSGGOG00000004914.3|UniProtKB=G3S278 G3S278 PTHR23327:SF5 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 generation of neurons#GO:0048699;protein catabolic process#GO:0030163;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;neuron apoptotic process#GO:0051402;apoptotic process#GO:0006915;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;neuron differentiation#GO:0030182;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;cell death#GO:0008219;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000013798.3|UniProtKB=G3RD68 G3RD68 UFL1 PTHR31057:SF0 E3 UFM1-PROTEIN LIGASE 1 E3 UFM1-PROTEIN LIGASE 1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 macroautophagy#GO:0016236;catabolic process#GO:0009056;response to stimulus#GO:0050896;autophagy#GO:0006914;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;reticulophagy#GO:0061709;response to stress#GO:0006950;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002007.3|UniProtKB=G3QHZ0 G3QHZ0 CPB2 PTHR11705:SF17 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE B2 carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;negative regulation of response to wounding#GO:1903035;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;negative regulation of blood coagulation#GO:0030195;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of multicellular organismal process#GO:0051239;fibrinolysis#GO:0042730;regulation of coagulation#GO:0050818;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;regulation of hemostasis#GO:1900046;regulation of response to wounding#GO:1903034;negative regulation of wound healing#GO:0061045;regulation of biological quality#GO:0065008;negative regulation of coagulation#GO:0050819;protein metabolic process#GO:0019538;negative regulation of hemostasis#GO:1900047;proteolysis#GO:0006508;regulation of wound healing#GO:0061041;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Plasminogen activating cascade#P00050>TAFI#P01247 GORGO|Ensembl=ENSGGOG00000016618.3|UniProtKB=G3RKE4 G3RKE4 CTSZ PTHR12411:SF929 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN Z hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000003564.3|UniProtKB=G3QLX9 G3QLX9 BCAT2 PTHR11825:SF39 SUBGROUP IIII AMINOTRANSFERASE BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;transaminase#PC00216 Alanine biosynthesis#P02724>Branched chain amino acid aminotransferase#P02815;Leucine biosynthesis#P02749>Branched chain amino acid aminotransferase#P03000;Isoleucine biosynthesis#P02748>Branched chain amino acid aminotransferase#P02994;Valine biosynthesis#P02785>Branched chain amino acid aminotransferase#P03215 GORGO|Ensembl=ENSGGOG00000024506.2|UniProtKB=G3RQM9 G3RQM9 PTHR31259:SF4 ENDOSOME-ASSOCIATED TRAFFICKING REGULATOR 1 ENDOSOME-ASSOCIATED-TRAFFICKING REGULATOR 1 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of localization#GO:0032879;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of organelle assembly#GO:1902115;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;regulation of cell projection assembly#GO:0060491;regulation of protein localization#GO:0032880;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;cilium#GO:0005929;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;midbody#GO:0030496;intracellular vesicle#GO:0097708;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;recycling endosome#GO:0055037;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000008077.3|UniProtKB=G3QYG1 G3QYG1 CEBPD PTHR23334:SF3 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN DELTA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cell differentiation#GO:0045595;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015859.3|UniProtKB=G3RIH0 G3RIH0 ELF4 PTHR11849:SF170 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Gene=TAS2R46|UniProtKB=Q645Z7 Q645Z7 TAS2R46 PTHR11394:SF66 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 46 taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040587.1|UniProtKB=A0A2I2ZE97 A0A2I2ZE97 PTHR45690:SF1 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 6 peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;binding#GO:0005488;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 inflammatory response#GO:0006954;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of response to stress#GO:0080134;acute inflammatory response#GO:0002526;defense response#GO:0006952;regulation of biological process#GO:0050789;response to stress#GO:0006950;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of response to external stimulus#GO:0032101 canonical inflammasome complex#GO:0061702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000040406.1|UniProtKB=A0A2I2Z2P1 A0A2I2Z2P1 MACIR PTHR31224:SF2 UNC119-BINDING PROTEIN C5ORF30 MACROPHAGE IMMUNOMETABOLISM REGULATOR negative regulation of gene expression#GO:0010629;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of cell motility#GO:2000145;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;negative regulation of macromolecule metabolic process#GO:0010605;regulation of locomotion#GO:0040012;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cell migration#GO:0030334;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 GORGO|Ensembl=ENSGGOG00000006187.3|UniProtKB=G3QTM4 G3QTM4 ESS2 PTHR12940:SF0 ES-2 PROTEIN - RELATED SPLICING FACTOR ESS-2 HOMOLOG spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000003586.3|UniProtKB=G3QM00 G3QM00 LOC101130783 PTHR15730:SF4 EXPERIMENTAL AUTOIMMUNE PROSTATITIS ANTIGEN 2-RELATED TRPM8 CHANNEL-ASSOCIATED FACTOR 2 transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein binding#GO:0005515 regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000010604.3|UniProtKB=A0A2I2Y487 A0A2I2Y487 TSPYL2 PTHR11875:SF72 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 2 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000009330.3|UniProtKB=G3RVT3 G3RVT3 CELF2 PTHR24012:SF699 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 2 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001864.3|UniProtKB=G3QHK3 G3QHK3 SERPINA5 PTHR11461:SF274 SERINE PROTEASE INHIBITOR, SERPIN PLASMA SERINE PROTEASE INHIBITOR peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000013246.3|UniProtKB=G3RBQ5 G3RBQ5 PRXL2A PTHR28630:SF35 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2A intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015768.3|UniProtKB=G3RI86 G3RI86 FZD6 PTHR11309:SF75 FRIZZLED FRIZZLED-6 signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;non-canonical Wnt signaling pathway#GO:0035567;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>Frizzled#P00475;Wnt signaling pathway#P00057>Frizzled#P01428;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 GORGO|Ensembl=ENSGGOG00000009428.3|UniProtKB=A0A2I2YDB2 A0A2I2YDB2 LLGL2 PTHR10241:SF20 LETHAL 2 GIANT LARVAE PROTEIN LLGL SCRIBBLE CELL POLARITY COMPLEX COMPONENT 2 cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;enzyme activator activity#GO:0008047;SNARE binding#GO:0000149;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function activator activity#GO:0140677;syntaxin binding#GO:0019905;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 cortical cytoskeleton organization#GO:0030865;organelle localization#GO:0051640;actin filament-based process#GO:0030029;regulation of Notch signaling pathway#GO:0008593;localization within membrane#GO:0051668;microtubule cytoskeleton organization#GO:0000226;secretion#GO:0046903;localization#GO:0051179;cortical actin cytoskeleton organization#GO:0030866;cell cycle#GO:0007049;establishment of cell polarity#GO:0030010;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;Golgi to plasma membrane transport#GO:0006893;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of spindle localization#GO:0051293;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;establishment or maintenance of cell polarity#GO:0007163;regulation of signaling#GO:0023051;cellular localization#GO:0051641;spindle localization#GO:0051653;secretion by cell#GO:0032940;post-Golgi vesicle-mediated transport#GO:0006892;cellular component organization#GO:0016043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;exocytosis#GO:0006887;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of establishment or maintenance of cell polarity#GO:0032878;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cortical cytoskeleton#GO:0030863;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000000349.3|UniProtKB=G3S8D1 G3S8D1 LOC101135633 PTHR22883:SF22 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC11-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 establishment of localization#GO:0051234;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;protein targeting to membrane#GO:0006612;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;establishment of protein localization to membrane#GO:0090150;response to stress#GO:0006950;establishment of protein localization#GO:0045184;defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;response to virus#GO:0009615;immune system process#GO:0002376;localization within membrane#GO:0051668;response to stimulus#GO:0050896;protein targeting#GO:0006605;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to virus#GO:0051607;antiviral innate immune response#GO:0140374 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004425.3|UniProtKB=G3SH27 G3SH27 PUDP PTHR18901:SF43 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000003597.3|UniProtKB=G3QM14 G3QM14 NRXN2 PTHR15036:SF52 PIKACHURIN-LIKE PROTEIN NEUREXIN-2 signaling receptor binding#GO:0005102;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023 localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;postsynaptic specialization organization#GO:0099084;protein localization to cell junction#GO:1902414;organelle assembly#GO:0070925;cognition#GO:0050890;synapse organization#GO:0050808;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;postsynapse organization#GO:0099173;cellular response to stimulus#GO:0051716;system process#GO:0003008;intracellular protein localization#GO:0008104;developmental process#GO:0032502;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;macromolecule localization#GO:0033036;animal gross anatomical part developmental process#GO:0160108;postsynaptic density organization#GO:0097106;nervous system process#GO:0050877;response to stimulus#GO:0050896;synapse assembly#GO:0007416;signaling#GO:0023052;excitatory synapse assembly#GO:1904861;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;nervous system development#GO:0007399;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;postsynaptic density assembly#GO:0097107;cellular process#GO:0009987 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786;presynaptic active zone membrane#GO:0048787;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000022093.2|UniProtKB=G3SGX0 G3SGX0 DNAI4 PTHR12442:SF12 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 4 binding#GO:0005488;protein binding#GO:0005515 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement#GO:0003341 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dynein complex#GO:0030286;axonemal dynein complex#GO:0005858 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000025415.2|UniProtKB=G3RZE1 G3RZE1 TBC1D8B PTHR22957:SF320 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 8B molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 renal system process#GO:0003014;system process#GO:0003008;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000000126.3|UniProtKB=A0A2I2ZK98 A0A2I2ZK98 SBSN PTHR23243:SF3 SUPRABASAL-SPECIFIC PROTEIN SUPRABASIN SUPRABASIN GORGO|Ensembl=ENSGGOG00000000101.3|UniProtKB=G3QCZ7 G3QCZ7 CEACAM18 PTHR44337:SF10 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM18 cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000006168.3|UniProtKB=A0A2I2YHF4 A0A2I2YHF4 RBMXL2 PTHR48034:SF3 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA-BINDING MOTIF PROTEIN, X-LINKED-LIKE-2 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001900.3|UniProtKB=G3QHN9 G3QHN9 SUSD2 PTHR13802:SF63 MUCIN 4-RELATED SUSHI DOMAIN-CONTAINING PROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000041313.1|UniProtKB=A0A2I2Y5T7 A0A2I2Y5T7 ZNF24 PTHR23226:SF127 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 24 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011304.3|UniProtKB=G3RNZ7 G3RNZ7 TNRC6C PTHR13020:SF9 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of metabolic process#GO:0009893;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000027253.2|UniProtKB=G3RPW2 G3RPW2 LOC101128254 PTHR11545:SF30 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 negative regulation of translation#GO:0017148;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000024079.2|UniProtKB=G3RWT1 G3RWT1 GIMD1 PTHR10903:SF103 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER GIMD1 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000010744.3|UniProtKB=G3R5A4 G3R5A4 HAPSTR1 PTHR31624:SF3 UPF0472 PROTEIN C16ORF72 HUWE1-ASSOCIATED PROTEIN MODIFYING STRESS RESPONSES 1 GORGO|Ensembl=ENSGGOG00000006790.3|UniProtKB=G3QV74 G3QV74 ZNF740 PTHR24404:SF51 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 740 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000000811.3|UniProtKB=G3QEU8 G3QEU8 SULT1A3 PTHR11783:SF308 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1A3-RELATED sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000043532.1|UniProtKB=A0A2I2ZBB0 A0A2I2ZBB0 PTHR11913:SF67 COFILIN-RELATED ADF-H DOMAIN-CONTAINING PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 protein depolymerization#GO:0051261;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;mitotic cell cycle process#GO:1903047;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301;cellular component disassembly#GO:0022411;cytoskeleton-dependent cytokinesis#GO:0061640;supramolecular fiber organization#GO:0097435;cytokinesis#GO:0000910;actin filament-based process#GO:0030029 cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;organelle#GO:0043226;actin cytoskeleton#GO:0015629;cell leading edge#GO:0031252;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000039463.1|UniProtKB=A0A2I2ZEK5 A0A2I2ZEK5 PTHR12748:SF2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 INSERTION DOMAIN-CONTAINING PROTEIN binding#GO:0005488;DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 nuclear origin of replication recognition complex#GO:0005664;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808;membraneless organelle#GO:0043228;nucleus#GO:0005634;nuclear pre-replicative complex#GO:0005656;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;pre-replicative complex#GO:0036387;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA replication preinitiation complex#GO:0031261;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 replication origin binding protein#PC00199;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000022229.2|UniProtKB=G3S7X7 G3S7X7 KCNK2 PTHR11003:SF21 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 2 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000003934.3|UniProtKB=G3QMV9 G3QMV9 PTHR13946:SF30 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE RBP11-LIKE DIMERISATION DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on RNA#GO:0140098 RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000002302.3|UniProtKB=A0A2I2YZR5 A0A2I2YZR5 LARGE2 PTHR12270:SF23 GLYCOSYLTRANSFERASE-RELATED XYLOSYL- AND GLUCURONYLTRANSFERASE LARGE2 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763;glucuronosyltransferase activity#GO:0015020 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000022805.2|UniProtKB=G3SHN8 G3SHN8 LRRCC1 PTHR15454:SF34 NISCHARIN RELATED LEUCINE-RICH REPEAT AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003330.3|UniProtKB=G3QLC4 G3QLC4 PEX12 PTHR12888:SF2 PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12 PEROXISOME ASSEMBLY PROTEIN 12 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular process#GO:0009987;peroxisome organization#GO:0007031;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000044123.1|UniProtKB=A0A2I2Y8K6 A0A2I2Y8K6 ARPC3 PTHR12391:SF10 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 GORGO|Ensembl=ENSGGOG00000007114.3|UniProtKB=A0A2I2YVD1 A0A2I2YVD1 TCAP PTHR15143:SF0 TELETHONIN TELETHONIN cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;structural molecule activity#GO:0005198;protein binding#GO:0005515 skeletal muscle contraction#GO:0003009;actomyosin structure organization#GO:0031032;circulatory system development#GO:0072359;cell differentiation#GO:0030154;heart process#GO:0003015;muscle system process#GO:0003012;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;animal organ development#GO:0048513;cytoskeleton organization#GO:0007010;heart development#GO:0007507;cellular component assembly#GO:0022607;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;system development#GO:0048731;tissue morphogenesis#GO:0048729;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;organelle assembly#GO:0070925;actin cytoskeleton organization#GO:0030036;myofibril assembly#GO:0030239;heart morphogenesis#GO:0003007;system process#GO:0003008;heart contraction#GO:0060047;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;developmental process#GO:0032502;muscle contraction#GO:0006936;detection of mechanical stimulus#GO:0050982;tissue development#GO:0009888;blood circulation#GO:0008015;detection of stimulus#GO:0051606;striated muscle cell development#GO:0055002;nervous system process#GO:0050877;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;response to stimulus#GO:0050896;protein-containing complex assembly#GO:0065003;anatomical structure morphogenesis#GO:0009653;response to abiotic stimulus#GO:0009628;anatomical structure formation involved in morphogenesis#GO:0048646;protein-containing complex organization#GO:0043933;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;muscle organ development#GO:0007517;cardiac muscle cell differentiation#GO:0055007;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;neuromuscular process#GO:0050905;cellular component assembly involved in morphogenesis#GO:0010927;striated muscle contraction#GO:0006941;muscle structure development#GO:0061061;animal organ morphogenesis#GO:0009887;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;response to mechanical stimulus#GO:0009612 myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;I band#GO:0031674;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;Z disc#GO:0030018;contractile muscle fiber#GO:0043292 GORGO|Ensembl=ENSGGOG00000003332.3|UniProtKB=G3SCU1 G3SCU1 PSEN2 PTHR10202:SF24 PRESENILIN PRESENILIN-2 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;proteolysis#GO:0006508;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;cell communication#GO:0007154;protein metabolic process#GO:0019538;monoatomic ion homeostasis#GO:0050801;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;membrane protein ectodomain proteolysis#GO:0006509;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cell surface receptor signaling pathway#GO:0007166;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219 catalytic complex#GO:1902494;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;aspartic protease#PC00053 Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Notch signaling pathway#P00045>Pen-2#P01113;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129 GORGO|Ensembl=ENSGGOG00000011310.3|UniProtKB=G3S9Q2 G3S9Q2 TDRD5 PTHR22948:SF29 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 5 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000017157.3|UniProtKB=G3RLT3 G3RLT3 RAB30 PTHR47977:SF64 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-30 nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi cisterna#GO:0031985;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000013178.3|UniProtKB=G3RBJ8 G3RBJ8 SDR42E1 PTHR10366:SF816 NAD DEPENDENT EPIMERASE/DEHYDRATASE SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E MEMBER 1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 dehydratase#PC00091;lyase#PC00144;metabolite interconversion enzyme#PC00262 GORGO|Gene=NDUFS5|UniProtKB=Q0MQH3 Q0MQH3 NDUFS5 PTHR15224:SF1 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933 transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;transporter complex#GO:1990351;organelle membrane#GO:0031090;respiratory chain complex I#GO:0045271;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000013888.3|UniProtKB=G3RDD9 G3RDD9 CLN5 PTHR15380:SF2 CEROID-LIPOFUSCINOSIS, NEURONAL 5 BIS(MONOACYLGLYCERO)PHOSPHATE SYNTHASE CLN5 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component organization#GO:0016043;organelle organization#GO:0006996;lytic vacuole organization#GO:0080171;cellular process#GO:0009987;lysosome organization#GO:0007040 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000005389.3|UniProtKB=A0A2I2Y2V8 A0A2I2Y2V8 DVL1 PTHR10878:SF5 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1-RELATED protein binding#GO:0005515;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447 GORGO|Ensembl=ENSGGOG00000007329.3|UniProtKB=G3QWL2 G3QWL2 LRRC15 PTHR45617:SF171 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010323.3|UniProtKB=G3R481 G3R481 PAG1 PTHR16322:SF0 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 negative regulation of T cell activation#GO:0050868;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;cellular response to stimulus#GO:0051716;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;negative regulation of leukocyte cell-cell adhesion#GO:1903038;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;negative regulation of cell activation#GO:0050866;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;regulation of cell adhesion#GO:0030155 cell periphery#GO:0071944;membrane microdomain#GO:0098857;membrane raft#GO:0045121;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013094.2|UniProtKB=G3RBC9 G3RBC9 LOC101149853 PTHR35975:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 11A SMALL INTEGRAL MEMBRANE PROTEIN 11 GORGO|Ensembl=ENSGGOG00000039641.1|UniProtKB=G3QVI9 G3QVI9 OR2AP1 PTHR26454:SF16 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AP1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008002.3|UniProtKB=G3QY93 G3QY93 IL21 PTHR14356:SF2 INTERLEUKIN-15-RELATED INTERLEUKIN-21 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of lymphocyte mediated immunity#GO:0002706;regulation of cell killing#GO:0031341;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of biosynthetic process#GO:0009891;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;regulation of response to biotic stimulus#GO:0002831;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated immunity#GO:0002703;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of gene expression#GO:0010628;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 Interleukin signaling pathway#P00036>Interleukin#P00970 GORGO|Ensembl=ENSGGOG00000002728.3|UniProtKB=G3S9K2 G3S9K2 FBXW8 PTHR44019:SF11 WD REPEAT-CONTAINING PROTEIN 55 F-BOX_WD REPEAT-CONTAINING PROTEIN 8 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000014140.4|UniProtKB=A0A2I2Z9A8 A0A2I2Z9A8 HS6ST2 PTHR12812:SF6 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009973.3|UniProtKB=A0A2I2YIU4 A0A2I2YIU4 TMED3 PTHR22811:SF60 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;COPI-coated vesicle#GO:0030137;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000000376.3|UniProtKB=G3SIQ9 G3SIQ9 TMEM87A PTHR21229:SF19 LUNG SEVEN TRANSMEMBRANE RECEPTOR GOLGI-PH REGULATING CATION CHANNEL localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;Golgi stack#GO:0005795;Golgi cisterna#GO:0031985;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000014569.3|UniProtKB=G3RF46 G3RF46 FOXL1 PTHR11829:SF204 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000012869.3|UniProtKB=G3RAS9 G3RAS9 EEF2 PTHR42908:SF35 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR 2 translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;hydrolase activity#GO:0016787;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000028568.2|UniProtKB=G3SJH2 G3SJH2 PTHR24412:SF385 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of small GTPase mediated signal transduction#GO:0051056;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;protein metabolic process#GO:0019538;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012528.3|UniProtKB=G3R9X7 G3R9X7 TROAP PTHR15289:SF3 TASTIN TASTIN GORGO|Ensembl=ENSGGOG00000001414.3|UniProtKB=G3QGE6 G3QGE6 ARFGEF2 PTHR10663:SF124 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 2 Golgi vesicle transport#GO:0048193;transport#GO:0006810;endosome organization#GO:0007032;vesicle organization#GO:0016050;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;Golgi to plasma membrane transport#GO:0006893 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000014481.3|UniProtKB=G3REY4 G3REY4 PC PTHR43778:SF4 PYRUVATE CARBOXYLASE PYRUVATE CARBOXYLASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 glucose metabolic process#GO:0006006;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ligase#PC00142;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Pyruvate Carboxylase#P03140 GORGO|Ensembl=ENSGGOG00000003698.3|UniProtKB=A0A2I2ZN57 A0A2I2ZN57 DLX1 PTHR24327:SF33 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;embryo development ending in birth or egg hatching#GO:0009792;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000001145.3|UniProtKB=G3QFP9 G3QFP9 TEX55 PTHR47110:SF1 TESTIS-SPECIFIC EXPRESSED PROTEIN 55 TESTIS-SPECIFIC EXPRESSED PROTEIN 55 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007847.3|UniProtKB=G3QXV4 G3QXV4 RPL39 PTHR19970:SF36 RIBOSOMAL PROTEIN L39E RIBOSOMAL PROTEIN EL39-LIKE 5-RELATED structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000002653.3|UniProtKB=G3QJM0 G3QJM0 PAPPA2 PTHR46130:SF1 LAMGL DOMAIN-CONTAINING PROTEIN PAPPALYSIN-2 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000027887.2|UniProtKB=G3S974 G3S974 OR4E2 PTHR26453:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010326.3|UniProtKB=G3R489 G3R489 GARRE1 PTHR15703:SF3 RIKEN CDNA 4931406P16 GENE GRANULE ASSOCIATED RAC AND RHOG EFFECTOR PROTEIN 1 binding#GO:0005488;protein-containing complex binding#GO:0044877 Rac protein signal transduction#GO:0016601;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000005186.3|UniProtKB=A0A2I2ZYC4 A0A2I2ZYC4 FEZ1 PTHR12394:SF4 ZYGIN FASCICULATION AND ELONGATION PROTEIN ZETA-1 axon#GO:0030424;neuron projection#GO:0043005;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001385.3|UniProtKB=A0A2I2YA07 A0A2I2YA07 CYGB PTHR46783:SF2 CYTOGLOBIN CYTOGLOBIN oxidoreductase activity#GO:0016491;tetrapyrrole binding#GO:0046906;catalytic activity#GO:0003824;binding#GO:0005488;heme binding#GO:0020037 GORGO|Ensembl=ENSGGOG00000027355.2|UniProtKB=G3RP28 G3RP28 LTC4S PTHR10250:SF4 MICROSOMAL GLUTATHIONE S-TRANSFERASE LEUKOTRIENE C4 SYNTHASE lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;glutathione transferase activity#GO:0004364;oxidoreductase activity#GO:0016491;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;icosanoid metabolic process#GO:0006690 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634 transferase#PC00220 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 GORGO|Ensembl=ENSGGOG00000000703.3|UniProtKB=G3RUI1 G3RUI1 NAPA PTHR13768:SF23 SOLUBLE NSF ATTACHMENT PROTEIN SNAP ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;protein transport#GO:0015031;cellular localization#GO:0051641;cellular component disassembly#GO:0022411;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;chemical synaptic transmission#GO:0007268;protein-containing complex disassembly#GO:0032984;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;macromolecule localization#GO:0033036;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 synapse#GO:0045202;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection terminus#GO:0044306;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;axon#GO:0030424;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;presynapse#GO:0098793;neuron projection#GO:0043005;cell junction#GO:0030054;axon terminus#GO:0043679 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006285.3|UniProtKB=G3RMR5 G3RMR5 ZNF57 PTHR24379:SF133 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 57 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000026399.2|UniProtKB=G3S4L8 G3S4L8 TUBB8 PTHR11588:SF429 TUBULIN TUBULIN BETA 8B-RELATED ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 tubulin#PC00228;cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 GORGO|Ensembl=ENSGGOG00000012046.3|UniProtKB=G3R8N7 G3R8N7 TMED4 PTHR22811:SF38 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 4 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000000421.3|UniProtKB=G3QDT7 G3QDT7 ZDHHC5 PTHR12349:SF3 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 regulation of innate immune response#GO:0045088;positive regulation of response to external stimulus#GO:0032103;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;positive regulation of signaling#GO:0023056;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000025196.2|UniProtKB=G3S491 G3S491 PDAP1 PTHR22055:SF5 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000007977.3|UniProtKB=G3RXK7 G3RXK7 RFC1 PTHR23389:SF35 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 REPLICATION FACTOR C SUBUNIT 1 catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 DNA replication#P00017>RFC#P00529 GORGO|Ensembl=ENSGGOG00000003188.3|UniProtKB=G3S550 G3S550 ST14 PTHR24253:SF50 TRANSMEMBRANE PROTEASE SERINE SUPPRESSOR OF TUMORIGENICITY 14 PROTEIN serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;cell differentiation#GO:0030154;primary metabolic process#GO:0044238;cellular developmental process#GO:0048869;animal organ development#GO:0048513;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;epidermis development#GO:0008544;metabolic process#GO:0008152;biosynthetic process#GO:0009058;skin development#GO:0043588;epithelial cell differentiation#GO:0030855;protein maturation#GO:0051604;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;gene expression#GO:0010467;epithelium development#GO:0060429;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000013017.3|UniProtKB=G3SFU1 G3SFU1 PCDH12 PTHR24028:SF42 CADHERIN-87A PROTOCADHERIN-12 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000040079.1|UniProtKB=G3RCL8 G3RCL8 SNX29 PTHR47194:SF4 SORTING NEXIN-29-RELATED SORTING NEXIN-29 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013852.3|UniProtKB=G3RDB8 G3RDB8 SLC44A3 PTHR12385:SF13 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098 GORGO|Ensembl=ENSGGOG00000002785.3|UniProtKB=G3RNS3 G3RNS3 LOC101136203 PTHR45616:SF52 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CUTICULAR HB3 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;skin development#GO:0043588;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;developmental process#GO:0032502;epidermis development#GO:0008544;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512 GORGO|Ensembl=ENSGGOG00000012798.3|UniProtKB=G3RAL1 G3RAL1 RGR PTHR24240:SF90 OPSIN RPE-RETINAL G PROTEIN-COUPLED RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;signal transduction#GO:0007165;detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;cellular response to radiation#GO:0071478;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000002193.3|UniProtKB=G3QIF2 G3QIF2 ZSWIM2 PTHR21540:SF3 RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2 E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010353.3|UniProtKB=G3RY77 G3RY77 LOC101126699 PTHR15298:SF7 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000009152.3|UniProtKB=G3R192 G3R192 LGALS4 PTHR11346:SF32 GALECTIN GALECTIN-4 carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000013780.3|UniProtKB=G3RD46 G3RD46 CTSG PTHR24271:SF13 KALLIKREIN-RELATED CATHEPSIN G catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000012730.3|UniProtKB=G3RAE2 G3RAE2 OR1D2 PTHR26453:SF618 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1D2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000428.3|UniProtKB=G3QDU3 G3QDU3 SMG9 PTHR14270:SF0 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519 GORGO|Ensembl=ENSGGOG00000014608.3|UniProtKB=A0A2I2YUH0 A0A2I2YUH0 COG1 PTHR31658:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000039027.1|UniProtKB=G3RPU1 G3RPU1 ZSWIM5 PTHR22619:SF2 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 5 Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000012773.3|UniProtKB=G3RAI7 G3RAI7 ISOC1 PTHR14119:SF17 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000015692.3|UniProtKB=A1YER2 A1YER2 HTATIP2 PTHR14097:SF7 OXIDOREDUCTASE HTATIP2 PROTEIN HTATIP2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of programmed cell death#GO:0043067 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000040333.1|UniProtKB=G3QSV9 G3QSV9 LOC101143734 PTHR45822:SF6 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 3-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to fatty acid#GO:0070542;cellular response to fatty acid#GO:0071398;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002916.3|UniProtKB=A0A2I2Z0G8 A0A2I2Z0G8 DCTN3 PTHR28360:SF1 DYNACTIN SUBUNIT 3 DYNACTIN SUBUNIT 3 cytokinesis#GO:0000910;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;cytoskeleton-dependent cytokinesis#GO:0061640 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000000013.3|UniProtKB=G3QCR8 G3QCR8 N4BP3 PTHR32274:SF1 NEDD4-BINDING PROTEIN 3 NEDD4-BINDING PROTEIN 3 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000000859.3|UniProtKB=G3QEY8 G3QEY8 EPHX1 PTHR21661:SF78 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE 1 hydrolase activity#GO:0016787;ether hydrolase activity#GO:0016803;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid metabolic process#GO:0032787;arachidonate metabolic process#GO:0019369;cellular process#GO:0009987;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000001468.3|UniProtKB=G3QGJ1 G3QGJ1 LBH PTHR14987:SF2 PROTEIN LBH-RELATED PROTEIN LBH biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000008079.3|UniProtKB=G3QYG6 G3QYG6 ANKEF1 PTHR24127:SF1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000006185.3|UniProtKB=A0A2I2YMX8 A0A2I2YMX8 LOC101138188 PTHR11528:SF131 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-ALPHA A2-RELATED purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ATP-dependent activity#GO:0140657;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein stabilization#GO:0050821;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to stress#GO:0006950;regulation of protein stability#GO:0031647;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622 Hsp90 family chaperone#PC00028;chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000007619.3|UniProtKB=G3QXB2 G3QXB2 YRDC PTHR17490:SF16 SUA5 THREONYLCARBAMOYL-AMP SYNTHASE tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005237.3|UniProtKB=G3QR91 G3QR91 MFN2 PTHR10465:SF1 TRANSMEMBRANE GTPASE FZO1 MITOFUSIN-2 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 mitochondrion localization#GO:0051646;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;organelle localization#GO:0051640;mitochondrion organization#GO:0007005;organelle fusion#GO:0048284;cellular process#GO:0009987;cellular component organization#GO:0016043;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 GORGO|Ensembl=ENSGGOG00000008993.3|UniProtKB=A0A2I2ZNK7 A0A2I2ZNK7 DPM1 PTHR43398:SF1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000016394.3|UniProtKB=G3RJV0 G3RJV0 PTHR24034:SF76 EGF-LIKE DOMAIN-CONTAINING PROTEIN COLLAGEN AND CALCIUM-BINDING EGF DOMAIN-CONTAINING PROTEIN 1 system development#GO:0048731;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;anatomical structure morphogenesis#GO:0009653 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000028480.2|UniProtKB=G3SIL7 G3SIL7 LOC101141112 PTHR20957:SF2 RNA-BINDING PROTEIN 48 RNA-BINDING PROTEIN 48 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000042128.1|UniProtKB=A0A2I2YGC9 A0A2I2YGC9 PTHR23341:SF6 HIGH MOBILITY GROUP PROTEINS HMG-A AND C SUBFAMILY NOT NAMED binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;DNA binding#GO:0003677 intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000008772.3|UniProtKB=G3R093 G3R093 PCP4 PTHR15359:SF7 IG-LIKE DOMAIN-CONTAINING PROTEIN CALMODULIN REGULATOR PROTEIN PCP4 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;calmodulin binding#GO:0005516 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 GORGO|Ensembl=ENSGGOG00000002948.3|UniProtKB=A0A2I2YK63 A0A2I2YK63 SCYL2 PTHR12984:SF18 SCY1-RELATED S/T PROTEIN KINASE-LIKE SCY1-LIKE PROTEIN 2 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000040863.1|UniProtKB=A0A2I2ZN25 A0A2I2ZN25 DPPA2 PTHR16073:SF10 DCR DOMAIN-CONTAINING PROTEIN DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 2 chromatin binding#GO:0003682;binding#GO:0005488 developmental process#GO:0032502;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000026322.2|UniProtKB=G3SGP0 G3SGP0 STC1 PTHR11245:SF1 STANNIOCALCIN STANNIOCALCIN-1 homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;calcium ion homeostasis#GO:0055074 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000042131.1|UniProtKB=A0A2I2YS88 A0A2I2YS88 PTHR11726:SF35 60S RIBOSOMAL PROTEIN L10 SUBFAMILY NOT NAMED structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000024254.2|UniProtKB=G3RRF2 G3RRF2 PTHR23252:SF24 INTIMAL THICKNESS RECEPTOR-RELATED TRANSMEMBRANE PROTEIN 145 GORGO|Ensembl=ENSGGOG00000026869.2|UniProtKB=A0A2I2ZIU5 A0A2I2ZIU5 PTHR45722:SF13 60S RIBOSOMAL PROTEIN L35 LARGE RIBOSOMAL SUBUNIT PROTEIN UL29 mRNA binding#GO:0003729;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000015792.3|UniProtKB=G3S242 G3S242 CHFR PTHR16079:SF4 UBIQUITIN LIGASE PROTEIN CHFR E3 UBIQUITIN-PROTEIN LIGASE CHFR catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011478.3|UniProtKB=G3R764 G3R764 MB PTHR47132:SF1 MYOGLOBIN MYOGLOBIN molecular carrier activity#GO:0140104;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 neuromuscular process#GO:0050905;localization#GO:0051179;cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;striated muscle contraction#GO:0006941;muscle contraction#GO:0006936;transport#GO:0006810;establishment of localization#GO:0051234;system process#GO:0003008;cellular oxidant detoxification#GO:0098869;cellular response to oxidative stress#GO:0034599;multicellular organismal process#GO:0032501;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;cellular detoxification#GO:1990748;nervous system process#GO:0050877;muscle system process#GO:0003012;response to stimulus#GO:0050896;skeletal muscle contraction#GO:0003009;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;response to reactive oxygen species#GO:0000302;response to stress#GO:0006950;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;sarcoplasm#GO:0016528 transfer/carrier protein#PC00219;globin#PC00107 GORGO|Ensembl=ENSGGOG00000025707.2|UniProtKB=A0A2I2ZRQ9 A0A2I2ZRQ9 PTHR12620:SF4 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT ZINC FINGER (CCCH TYPE), RNA-BINDING MOTIF AND SERINE_ARGININE RICH 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000016872.3|UniProtKB=G3RL26 G3RL26 ZNF473 PTHR24377:SF787 IP01015P-RELATED ZINC FINGER PROTEIN 473 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010938.3|UniProtKB=A0A2I2Y617 A0A2I2Y617 ANKS3 PTHR24184:SF29 SI:CH211-189E2.2 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 3 cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000007629.3|UniProtKB=G3QXC4 G3QXC4 LCA5 PTHR16650:SF10 C21ORF13-RELATED LEBERCILIN cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;microtubule-based transport#GO:0099111;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;cellular component organization#GO:0016043 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000012474.3|UniProtKB=A0A2I2ZYG3 A0A2I2ZYG3 PCBP4 PTHR10288:SF166 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA splicing#GO:0043484;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003462.3|UniProtKB=A0A2I2YFV4 A0A2I2YFV4 LMNB2 PTHR45721:SF2 LAMIN DM0-RELATED LAMIN-B2 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;membrane organization#GO:0061024;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule localization#GO:0033036;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;protein localization to nucleus#GO:0034504;regulation of metabolic process#GO:0019222;intracellular protein localization#GO:0008104;regulation of gene expression#GO:0010468;nuclear envelope organization#GO:0006998;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;transport#GO:0006810;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;nuclear migration#GO:0007097;heterochromatin formation#GO:0031507;localization#GO:0051179;localization within membrane#GO:0051668;organelle localization#GO:0051640;endomembrane system organization#GO:0010256;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;cellular localization#GO:0051641 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;nucleus#GO:0005634 FAS signaling pathway#P00020>Nuclear Lamin#P00616 GORGO|Ensembl=ENSGGOG00000001750.3|UniProtKB=G3QHA0 G3QHA0 LOC101141821 PTHR13718:SF90 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;mitochondrion#GO:0005739;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;cytosolic small ribosomal subunit#GO:0022627;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000042077.1|UniProtKB=A0A2I2YAB3 A0A2I2YAB3 TMEM134 PTHR13558:SF1 TRANSMEMBRANE PROTEIN 134 TRANSMEMBRANE PROTEIN 134 GORGO|Ensembl=ENSGGOG00000010631.3|UniProtKB=G3R4Z7 G3R4Z7 PTHR15336:SF21 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 6 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex III#GO:0045275;catalytic complex#GO:1902494 reductase#PC00198;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003507.3|UniProtKB=G3QLT0 G3QLT0 OTUD3 PTHR12419:SF117 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 3 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;regulation of protein stability#GO:0031647 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000038351.1|UniProtKB=A0A2I2YU44 A0A2I2YU44 DUSP19 PTHR46377:SF1 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of JNK cascade#GO:0046328;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of MAPK cascade#GO:0043408;regulation of intracellular signal transduction#GO:1902531 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000023783.2|UniProtKB=G3S6X8 G3S6X8 LOC101132324 PTHR24304:SF1 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 7A1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 monocarboxylic acid metabolic process#GO:0032787;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;homeostatic process#GO:0042592;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;monocarboxylic acid biosynthetic process#GO:0072330 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000014645.3|UniProtKB=G3R3B6 G3R3B6 CXCL6 PTHR12015:SF201 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 6 chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664 antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;neutrophil chemotaxis#GO:0030593;response to lipopolysaccharide#GO:0032496;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;neutrophil migration#GO:1990266;taxis#GO:0042330;response to chemical#GO:0042221;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to molecule of bacterial origin#GO:0002237;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;biological process involved in interspecies interaction between organisms#GO:0044419;leukocyte migration#GO:0050900;cellular response to molecule of bacterial origin#GO:0071219;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;immune response#GO:0006955;cell migration#GO:0016477;response to other organism#GO:0051707;response to bacterium#GO:0009617;inflammatory response#GO:0006954;chemotaxis#GO:0006935;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000011654.3|UniProtKB=G3R7M7 G3R7M7 PDSS1 PTHR12001:SF78 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1 transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 isoprenoid metabolic process#GO:0006720;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;isoprenoid biosynthetic process#GO:0008299;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 GORGO|Ensembl=ENSGGOG00000007310.3|UniProtKB=G3S1U0 G3S1U0 ZNF888 PTHR24393:SF88 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 808 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000026147.2|UniProtKB=G3RWT4 G3RWT4 PTHR10562:SF131 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 2-RELATED binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515 protein sumoylation#GO:0016925;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 p53 pathway#P00059>Sumo-1 ligase#P04635 GORGO|Ensembl=ENSGGOG00000006778.3|UniProtKB=G3QV65 G3QV65 LOC101141137 PTHR48001:SF123 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7G3 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000038911.1|UniProtKB=A0A2I2YTZ0 A0A2I2YTZ0 SUCLG2 PTHR11815:SF11 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 tricarboxylic acid cycle#GO:0006099;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000008093.3|UniProtKB=G3QYH4 G3QYH4 CD180 PTHR24366:SF171 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC33 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000040149.1|UniProtKB=A0A2I2Z829 A0A2I2Z829 PTHR14969:SF18 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE POLYISOPRENOID DIPHOSPHATE_PHOSPHATE PHOSPHOHYDROLASE PLPP6 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;dephosphorylation#GO:0016311;lipid modification#GO:0030258;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000000587.3|UniProtKB=A0A2I2ZEG4 A0A2I2ZEG4 PTGER3 PTHR11866:SF10 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of localization#GO:0032879;system process#GO:0003008;regulation of transport#GO:0051049;defense response#GO:0006952;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of system process#GO:0044057;muscle contraction#GO:0006936;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of biological quality#GO:0065008;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;inflammatory response#GO:0006954;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to stimulus#GO:0050896;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;signaling#GO:0023052;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;muscle system process#GO:0003012;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836;PI3 kinase pathway#P00048>GPCR#P01204 GORGO|Ensembl=ENSGGOG00000007766.3|UniProtKB=G3QXP9 G3QXP9 CCT7 PTHR11353:SF22 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ETA metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058 protein folding chaperone complex#GO:0101031;chaperonin-containing T-complex#GO:0005832;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000010302.3|UniProtKB=G3R464 G3R464 PTHR47979:SF7 DRAB11-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 27 HOMOLOG pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 vesicle-mediated transport#GO:0016192;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;microtubule-based transport#GO:0099111 cilium#GO:0005929;intracellular organelle#GO:0043229;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intraciliary transport particle B#GO:0030992;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000040681.1|UniProtKB=A0A2I2Y7Q4 A0A2I2Y7Q4 TSBP1 PTHR14368:SF7 TESTIS-EXPRESSED BASIC PROTEIN 1 TESTIS-EXPRESSED BASIC PROTEIN 1 GORGO|Ensembl=ENSGGOG00000006182.3|UniProtKB=A0A2I2Z5V8 A0A2I2Z5V8 CAPRIN2 PTHR22922:SF5 GPI-ANCHORED PROTEIN P137 CAPRIN-2 protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000022589.2|UniProtKB=G3SCN9 G3SCN9 PTHR21522:SF60 PROTON CHANNEL OTOP OTOP1 binding#GO:0005488;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;identical protein binding#GO:0042802;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 sensory organ development#GO:0007423;developmental process#GO:0032502;transport#GO:0006810;multicellular organism development#GO:0007275;proton transmembrane transport#GO:1902600;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;establishment of localization#GO:0051234;anatomical structure formation involved in morphogenesis#GO:0048646;inner ear morphogenesis#GO:0042472;inner ear development#GO:0048839;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;embryo development#GO:0009790;animal gross anatomical part developmental process#GO:0160108;biomineral tissue development#GO:0031214;embryonic organ development#GO:0048568;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;anatomical structure development#GO:0048856;monoatomic ion transport#GO:0006811;ear development#GO:0043583;anatomical structure morphogenesis#GO:0009653;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015592.3|UniProtKB=G3S589 G3S589 PRPF40A PTHR11864:SF20 PRE-MRNA-PROCESSING PROTEIN PRP40 PRE-MRNA-PROCESSING FACTOR 40 HOMOLOG A nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000044166.1|UniProtKB=A0A2I2ZCY9 A0A2I2ZCY9 PTHR19433:SF85 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 17-RELATED response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000024452.2|UniProtKB=G3RRQ2 G3RRQ2 APOM PTHR32028:SF1 APOLIPOPROTEIN M APOLIPOPROTEIN M lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;cellular process#GO:0009987;cholesterol efflux#GO:0033344;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cholesterol transport#GO:0030301;biological regulation#GO:0065007;lipid transport#GO:0006869;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;transport#GO:0006810;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;sterol transport#GO:0015918;plasma lipoprotein particle clearance#GO:0034381;establishment of localization#GO:0051234 lipoprotein particle#GO:1990777;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;high-density lipoprotein particle#GO:0034364;plasma lipoprotein particle#GO:0034358;very-low-density lipoprotein particle#GO:0034361;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000016068.3|UniProtKB=A0A2I2YZ66 A0A2I2YZ66 VCAN PTHR22804:SF6 AGGRECAN/VERSICAN PROTEOGLYCAN VERSICAN CORE PROTEIN nervous system development#GO:0007399;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;system development#GO:0048731;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;extracellular region#GO:0005576;cell junction#GO:0030054 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000038978.1|UniProtKB=A0A2I2YNG6 A0A2I2YNG6 ZNF148 PTHR24404:SF53 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 148 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000009317.3|UniProtKB=G3R1M4 G3R1M4 MUC1 PTHR10006:SF19 MUCIN-1-RELATED MUCIN-1 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000015644.3|UniProtKB=G3RHY7 G3RHY7 POLK PTHR11076:SF33 DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER DNA POLYMERASE KAPPA catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887 translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA synthesis involved in DNA replication#GO:0090592;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000008438.3|UniProtKB=G3RQ18 G3RQ18 ZBTB7C PTHR46105:SF7 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7C sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001929.3|UniProtKB=G3QHR5 G3QHR5 PRDM1 PTHR16515:SF59 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 1 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Gene=UBC|UniProtKB=P0CG66 P0CG66 UBC PTHR10666:SF530 UBIQUITIN POLYUBIQUITIN-C structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;nucleus#GO:0005634;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000016555.3|UniProtKB=G3RK95 G3RK95 SEMA6D PTHR11036:SF65 SEMAPHORIN SEMAPHORIN-6D molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000001437.3|UniProtKB=Q0MQ98 Q0MQ98 COXFA4 PTHR14256:SF4 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE SUBUNIT FA4 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;transporter complex#GO:1990351 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000024897.2|UniProtKB=G3SBN1 G3SBN1 USO1 PTHR10013:SF7 GENERAL VESICULAR TRANSPORT FACTOR P115 GENERAL VESICULAR TRANSPORT FACTOR P115 membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;membrane fusion#GO:0061025;cellular component organization#GO:0016043;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi stack#GO:0005795;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000003301.3|UniProtKB=A0A2I2ZXL7 A0A2I2ZXL7 UTP15 PTHR19924:SF26 UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;rRNA processing#GO:0006364;regulation of transcription by RNA polymerase I#GO:0006356;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase I#GO:0045943;positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000004988.3|UniProtKB=A0A2I2Z7M5 A0A2I2Z7M5 HIBCH PTHR43176:SF15 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824;deacylase activity#GO:0160215;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;hydrolase activity#GO:0016787 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000022699.2|UniProtKB=A0A2I2ZSC7 A0A2I2ZSC7 VPS50 PTHR13258:SF0 SYNDETIN SYNDETIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization within membrane#GO:0051668;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;recycling endosome#GO:0055037 GORGO|Ensembl=ENSGGOG00000015443.3|UniProtKB=A0A2I2YFV5 A0A2I2YFV5 SNCAIP PTHR22882:SF3 SYNPHILIN-1 SYNPHILIN-1 binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 Parkinson disease#P00049>Synphilin#P01225 GORGO|Ensembl=ENSGGOG00000015058.3|UniProtKB=G3RGF0 G3RGF0 ZSWIM9 PTHR47086:SF1 BTB DOMAIN-CONTAINING PROTEIN ZINC FINGER SWIM-TYPE CONTAINING 9 GORGO|Ensembl=ENSGGOG00000014783.3|UniProtKB=G3RFP6 G3RFP6 THTPA PTHR14586:SF1 THIAMINE-TRIPHOSPHATASE THIAMINE-TRIPHOSPHATASE hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787 cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 Thiamin metabolism#P02780>Thiamine triphosphatase#P03184 GORGO|Ensembl=ENSGGOG00000009849.3|UniProtKB=G3S284 G3S284 WWC2 PTHR14791:SF26 BOMB/KIRA PROTEINS PROTEIN WWC2 enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;regulation of multicellular organismal process#GO:0051239;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cell migration#GO:0016477;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000040203.1|UniProtKB=A0A2I2ZDX3 A0A2I2ZDX3 PTHR11985:SF25 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000001732.3|UniProtKB=A0A2I2ZLY9 A0A2I2ZLY9 PXYLP1 PTHR11567:SF213 ACID PHOSPHATASE-RELATED 2-PHOSPHOXYLOSE PHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;glycoprotein biosynthetic process#GO:0009101;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000004516.3|UniProtKB=G3QPD7 G3QPD7 KAZALD1 PTHR14186:SF21 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED KAZAL-TYPE SERINE PROTEASE INHIBITOR DOMAIN-CONTAINING PROTEIN 1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;interstitial matrix#GO:0005614;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012348.3|UniProtKB=G3RS28 G3RS28 CFH PTHR45785:SF7 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H complement binding#GO:0001848;binding#GO:0005488;protein binding#GO:0005515 positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;immune response#GO:0006955;complement activation#GO:0006956;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;immune system process#GO:0002376;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 complement component#PC00078 GORGO|Ensembl=ENSGGOG00000009245.3|UniProtKB=G3R1H0 G3R1H0 RUVBL2 PTHR11093:SF2 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 2 DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular component assembly#GO:0022607;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component biogenesis#GO:0044085;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;protein-RNA complex organization#GO:0071826;regulation of gene expression#GO:0010468;protein-containing complex organization#GO:0043933;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular organelle lumen#GO:0070013;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;Ino80 complex#GO:0031011;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000007409.3|UniProtKB=G3QWU3 G3QWU3 LOC101144655 PTHR45736:SF6 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 2 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000026488.2|UniProtKB=A0A2I2ZTU6 A0A2I2ZTU6 LOC101144003 PTHR14224:SF81 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 1-RELATED ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000022150.2|UniProtKB=G3RVP8 G3RVP8 DNAJC24 PTHR45255:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;molecular function activator activity#GO:0140677;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000008775.3|UniProtKB=G3SK99 G3SK99 SERPINA9 PTHR11461:SF40 SERINE PROTEASE INHIBITOR, SERPIN SERPIN A9 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000041279.1|UniProtKB=A0A2I2ZSX4 A0A2I2ZSX4 PTHR22765:SF267 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;biological regulation#GO:0065007 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002237.3|UniProtKB=G3QIJ1 G3QIJ1 FGF16 PTHR11486:SF27 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 16 growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000041734.1|UniProtKB=A0A2I2ZRT7 A0A2I2ZRT7 LOC101124738 PTHR38504:SF1 KERATIN-ASSOCIATED PROTEIN 7-1 KERATIN-ASSOCIATED PROTEIN 7-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000005244.3|UniProtKB=G3QR93 G3QR93 XKR7 PTHR16024:SF7 XK-RELATED PROTEIN XK-RELATED PROTEIN 7 regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;phagocytosis#GO:0006909;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;lipid transport#GO:0006869;macromolecule localization#GO:0033036;localization#GO:0051179;anatomical structure development#GO:0048856;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;cell death#GO:0008219;programmed cell death#GO:0012501;cellular component organization or biogenesis#GO:0071840;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;import into cell#GO:0098657;membrane invagination#GO:0010324;endomembrane system organization#GO:0010256;cellular process#GO:0009987;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;lipid localization#GO:0010876;endocytosis#GO:0006897;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cellular component organization#GO:0016043 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000017170.3|UniProtKB=G3RLU5 G3RLU5 FILIP1 PTHR23166:SF3 FILAMIN/GPBP-INTERACTING PROTEIN FILAMIN-A-INTERACTING PROTEIN 1 localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to cytoskeleton#GO:0044380 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000039536.1|UniProtKB=A0A2I2ZRR5 A0A2I2ZRR5 LOC109028564 PTHR13172:SF4 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B SUBFAMILY NOT NAMED protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial envelope#GO:0005740;mitochondrial intermembrane space#GO:0005758 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000010673.3|UniProtKB=G3R544 G3R544 CA3 PTHR18952:SF127 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 3 hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;cellular response to hypoxia#GO:0071456;response to hypoxia#GO:0001666;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000036263.1|UniProtKB=G3RYZ3 G3RYZ3 LOC101127473 PTHR26452:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037533.1|UniProtKB=A0A2I2ZD77 A0A2I2ZD77 PTHR45793:SF17 HOMEOBOX PROTEIN HOMEOBOX DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000014123.3|UniProtKB=A0A2I2Z942 A0A2I2Z942 SATB2 PTHR15116:SF15 DNA-BINDING PROTEIN SATB FAMILY MEMBER DNA-BINDING PROTEIN SATB2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;Lambda repressor-like transcription factor#PC00245 GORGO|Ensembl=ENSGGOG00000041698.1|UniProtKB=A0A2I2ZSF5 A0A2I2ZSF5 STK33 PTHR44167:SF6 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED SERINE_THREONINE-PROTEIN KINASE 33 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023501.2|UniProtKB=G3RPF8 G3RPF8 ZRANB2 PTHR12999:SF22 ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;carbohydrate derivative binding#GO:0097367;lipopolysaccharide binding#GO:0001530;lipid binding#GO:0008289 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000008805.3|UniProtKB=G3RZR5 G3RZR5 ZNF292 PTHR15507:SF14 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN 292 DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011752.3|UniProtKB=G3R7W2 G3R7W2 CEP295NL PTHR21553:SF33 ALMS1-RELATED CEP295 N-TERMINAL-LIKE PROTEIN regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000011405.3|UniProtKB=G3SA74 G3SA74 DENND2A PTHR15288:SF3 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2A guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000006032.3|UniProtKB=G3QT93 G3QT93 SRGAP2 PTHR14166:SF6 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 2-RELATED enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 multicellular organism development#GO:0007275;regulation of cell migration#GO:0030334;developmental process#GO:0032502;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;regulation of locomotion#GO:0040012;nervous system development#GO:0007399;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;system development#GO:0048731;regulation of biological quality#GO:0065008;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;animal gross anatomical part developmental process#GO:0160108;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic spine#GO:0043197;neuron projection#GO:0043005;postsynapse#GO:0098794;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000006624.3|UniProtKB=G3R2C1 G3R2C1 LOC101142998 PTHR16675:SF294 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, C ALPHA CHAIN binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823;peptide binding#GO:0042277;protein binding#GO:0005515 positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000003268.3|UniProtKB=A0A2I2YS43 A0A2I2YS43 PTHR12566:SF9 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1 RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182;translation factor activity#GO:0180051 negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of translation#GO:0017148;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;neuron projection#GO:0043005;nucleus#GO:0005634;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000014373.3|UniProtKB=G3REM8 G3REM8 ZNF232 PTHR23226:SF54 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 232 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010682.3|UniProtKB=G3R557 G3R557 TTC7B PTHR23083:SF365 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT PROTEIN 7B protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;phosphatidylinositol phosphate biosynthetic process#GO:0046854;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;organophosphate biosynthetic process#GO:0090407;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000027079.2|UniProtKB=G3SDY1 G3SDY1 TXNDC8 PTHR10438:SF230 THIOREDOXIN THIOREDOXIN DOMAIN-CONTAINING PROTEIN 8 oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;cell redox homeostasis#GO:0045454;multicellular organismal reproductive process#GO:0048609;cellular homeostasis#GO:0019725;developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;homeostatic process#GO:0042592;reproductive process#GO:0022414 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000006432.3|UniProtKB=G3QU89 G3QU89 RPL31 PTHR10956:SF51 60S RIBOSOMAL PROTEIN L31 LARGE RIBOSOMAL SUBUNIT PROTEIN EL31 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013713.3|UniProtKB=G3RCY9 G3RCY9 NDST1 PTHR10605:SF30 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;deacetylase activity#GO:0019213;transferase activity#GO:0016740;deacylase activity#GO:0160215;catalytic activity#GO:0003824 proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000005645.3|UniProtKB=G3QS94 G3QS94 RPS8 PTHR10394:SF12 40S RIBOSOMAL PROTEIN S8 SMALL RIBOSOMAL SUBUNIT PROTEIN ES8 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000037686.1|UniProtKB=G3S1N9 G3S1N9 RWDD2A PTHR15955:SF3 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2A ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005326.3|UniProtKB=G3QRG1 G3QRG1 ZNF343 PTHR23226:SF403 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 169 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012949.3|UniProtKB=G3RAZ4 G3RAZ4 PTHR12277:SF55 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17C catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;palmitoyl hydrolase activity#GO:0098599 regulation of synapse structure or activity#GO:0050803;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of postsynapse organization#GO:0099175 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000008459.3|UniProtKB=G3QZF9 G3QZF9 NKX6-1 PTHR24340:SF31 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000012240.3|UniProtKB=G3R961 G3R961 RDH8 PTHR43391:SF8 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE 8 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022 terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;cellular process#GO:0009987;biological regulation#GO:0065007;hormone metabolic process#GO:0042445 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000004153.3|UniProtKB=G3QNG0 G3QNG0 SDC4 PTHR10915:SF3 SYNDECAN SYNDECAN-4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell junction#GO:0030054;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002789.3|UniProtKB=A0A2I2YWM5 A0A2I2YWM5 LOC101151260 PTHR45616:SF43 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CUTICULAR HB5 structural molecule activity#GO:0005198 developmental process#GO:0032502;epidermis development#GO:0008544;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000016458.3|UniProtKB=G3RK04 G3RK04 F13B PTHR45785:SF3 COMPLEMENT FACTOR H-RELATED COAGULATION FACTOR XIII B CHAIN coagulation#GO:0050817;response to wounding#GO:0009611;hemostasis#GO:0007599;response to stress#GO:0006950;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;multicellular organismal process#GO:0032501;regulation of biological quality#GO:0065008;wound healing#GO:0042060;blood coagulation#GO:0007596 complement component#PC00078 Blood coagulation#P00011>FXIII#P00453;Vitamin D metabolism and pathway#P04396>RXR#P04602;Blood coagulation#P00011>FXIIIa#P00419 GORGO|Ensembl=ENSGGOG00000013702.3|UniProtKB=G3RRI8 G3RRI8 IFITM2 PTHR13999:SF8 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 2 cell communication#GO:0007154;response to virus#GO:0009615;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;biological regulation#GO:0065007;response to other organism#GO:0051707;immune response#GO:0006955;response to peptide#GO:1901652;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;response to type II interferon#GO:0034341;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015475.3|UniProtKB=G3RHH8 G3RHH8 RHBDF2 PTHR45965:SF2 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 2 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;regulation of protein secretion#GO:0050708 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000011613.4|UniProtKB=G3R7J0 G3R7J0 MAPK1 PTHR24055:SF584 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Parkinson disease#P00049>ERK#P01211;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>MAPK#P00269;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Endothelin signaling pathway#P00019>ERK#P00566;Ras Pathway#P04393>ERK#P04542;T cell activation#P00053>ERK#P01300;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;CCKR signaling map#P06959>MAPK1/3#P07228;Integrin signalling pathway#P00034>ERK#P00907;Interleukin signaling pathway#P00036>ERK#P00965;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MAPK#P05937;B cell activation#P00010>ERK#P00371;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;CCKR signaling map#P06959>MAPK1#P07166;VEGF signaling pathway#P00056>MEK#P01402;FGF signaling pathway#P00021>ERK1-2#P00627;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Angiogenesis#P00005>Erk#P00203;Toll receptor signaling pathway#P00054>ERK2#P01356;Gonadotropin-releasing hormone receptor pathway#P06664>ERK1/2#P06786;VEGF signaling pathway#P00056>Erk#P01407 GORGO|Ensembl=ENSGGOG00000013761.3|UniProtKB=G3S6J9 G3S6J9 TBXA2R PTHR11866:SF5 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER THROMBOXANE A2 RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;system process#GO:0003008;defense response#GO:0006952;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of blood pressure#GO:0008217;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;inflammatory response#GO:0006954;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of blood pressure#GO:0045777;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004114.3|UniProtKB=G3SA32 G3SA32 CLRN2 PTHR31548:SF5 CLARIN CLARIN-2 GORGO|Ensembl=ENSGGOG00000028344.2|UniProtKB=G3RYX7 G3RYX7 PTHR11442:SF50 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT DELTA tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488 erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;localization#GO:0051179;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;cell development#GO:0048468;homeostatic process#GO:0042592;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 globin#PC00107;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000042887.1|UniProtKB=A0A2I2ZXD3 A0A2I2ZXD3 OR4D10 PTHR48002:SF68 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D10 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025269.2|UniProtKB=G3RN04 G3RN04 THNSL1 PTHR43515:SF1 THREONINE SYNTHASE-LIKE 1 THREONINE SYNTHASE-LIKE 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 Threonine biosynthesis#P02781>Threonine synthase#P03190 GORGO|Ensembl=ENSGGOG00000022802.2|UniProtKB=A0A2I2ZQR1 A0A2I2ZQR1 PTHR13718:SF119 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000028452.2|UniProtKB=G3RUG6 G3RUG6 PFN4 PTHR11604:SF2 PROFILIN PROFILIN-4 protein binding#GO:0005515;binding#GO:0005488;actin monomer binding#GO:0003785;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000009120.3|UniProtKB=G3R157 G3R157 DNAJC19 PTHR12763:SF56 FAMILY NOT NAMED MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM14 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671 protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542 mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000011141.3|UniProtKB=G3RSN7 G3RSN7 RPGRIP1L PTHR14240:SF4 RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN PROTEIN FANTOM G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;ciliary transition zone#GO:0035869;cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000036415.1|UniProtKB=A0A2I2Z8U6 A0A2I2Z8U6 GALNTL5 PTHR11675:SF17 N-ACETYLGALACTOSAMINYLTRANSFERASE INACTIVE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE-LIKE PROTEIN 5 signaling receptor binding#GO:0005102;binding#GO:0005488;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;protein binding#GO:0005515;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 regulation of Notch signaling pathway#GO:0008593;spermatid development#GO:0007286;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;biosynthetic process#GO:0009058;male gamete generation#GO:0048232;regulation of signaling#GO:0023051;spermatid differentiation#GO:0048515;regulation of biological process#GO:0050789;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;cellular process#GO:0009987 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000025970.2|UniProtKB=G3RM59 G3RM59 LOC101127680 PTHR48018:SF55 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000964.3|UniProtKB=G3S5X9 G3S5X9 NANOS3 PTHR12887:SF12 NANOS PROTEIN NANOS HOMOLOG 3 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;oogenesis#GO:0048477;negative regulation of translation#GO:0017148;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;reproductive process#GO:0022414 cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000037380.1|UniProtKB=A0A2I2ZW93 A0A2I2ZW93 TIMP2 PTHR11844:SF24 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 2 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;response to peptide#GO:1901652;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of catabolic process#GO:0009894;regulation of proteolysis#GO:0030162;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;negative regulation of protein catabolic process#GO:0042177;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;response to hormone#GO:0009725 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000002375.3|UniProtKB=A0A2I2ZSS7 A0A2I2ZSS7 NUDT21 PTHR13047:SF0 PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 5 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000037802.1|UniProtKB=A0A2I2Z0I9 A0A2I2Z0I9 PTHR18849:SF4 LEUCINE RICH REPEAT PROTEIN LEUCINE RICH REPEAT CONTAINING 77 GORGO|Ensembl=ENSGGOG00000002186.3|UniProtKB=G3QIE3 G3QIE3 NAT16 PTHR47403:SF3 LOC100145250 PROTEIN N-ACETYLTRANSFERASE 16-RELATED GORGO|Ensembl=ENSGGOG00000006608.3|UniProtKB=G3QUR5 G3QUR5 ARR3 PTHR11792:SF19 ARRESTIN ARRESTIN-C protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 establishment of localization#GO:0051234;import into cell#GO:0098657;system process#GO:0003008;receptor-mediated endocytosis#GO:0006898;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;transport#GO:0006810;regulation of G protein-coupled receptor signaling pathway#GO:0008277;vesicle-mediated transport#GO:0016192;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;receptor internalization#GO:0031623;cellular process#GO:0009987;localization#GO:0051179;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;sensory perception#GO:0007600;regulation of signaling#GO:0023051;nervous system process#GO:0050877;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>beta-arrestin#P01456 GORGO|Ensembl=ENSGGOG00000038719.1|UniProtKB=A0A2I2YEY4 A0A2I2YEY4 PTHR47981:SF22 RAB FAMILY RAS-RELATED PROTEIN RAB-7B ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;endocytosis#GO:0006897;organelle assembly#GO:0070925;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;vacuole organization#GO:0007033;cellular localization#GO:0051641;localization#GO:0051179;lysosome organization#GO:0007040;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;lytic vacuole organization#GO:0080171;transport#GO:0006810;vacuolar transport#GO:0007034;phagocytosis#GO:0006909;intracellular transport#GO:0046907;phagolysosome assembly#GO:0001845;vesicle organization#GO:0016050;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lytic vacuole#GO:0000323;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000008198.3|UniProtKB=A0A2I2Z8G2 A0A2I2Z8G2 SH3GL1 PTHR14167:SF63 SH3 DOMAIN-CONTAINING ENDOPHILIN-A2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytoplasm#GO:0005737;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;presynapse#GO:0098793;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007327.3|UniProtKB=A0A2I2YC36 A0A2I2YC36 SLCO2B1 PTHR11388:SF87 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2B1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013282.3|UniProtKB=G3RBT9 G3RBT9 CNIH1 PTHR12290:SF10 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 1 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006244.3|UniProtKB=A0A2I2YJD5 A0A2I2YJD5 MFAP1 PTHR15327:SF0 MICROFIBRIL-ASSOCIATED PROTEIN MICROFIBRILLAR-ASSOCIATED PROTEIN 1 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000014812.3|UniProtKB=G3RFS6 G3RFS6 PTHR22993:SF27 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 1 hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA glycosylase#PC00010 GORGO|Ensembl=ENSGGOG00000000245.3|UniProtKB=G3S852 G3S852 EIF2AK4 PTHR11042:SF202 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EIF-2-ALPHA KINASE GCN2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 negative regulation of translation#GO:0017148;cellular response to stress#GO:0033554;regulation of translational initiation#GO:0006446;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to amino acid starvation#GO:0034198;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;response to nutrient levels#GO:0031667;negative regulation of macromolecule metabolic process#GO:0010605 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000038913.1|UniProtKB=A0A2I2Y6E8 A0A2I2Y6E8 TM4SF19 PTHR14198:SF22 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 19 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016756.3|UniProtKB=G3RKR6 G3RKR6 TRAF4 PTHR10131:SF164 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009930.3|UniProtKB=G3S6T4 G3S6T4 LOC101128182 PTHR24381:SF303 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 705A-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000013650.3|UniProtKB=G3RCS9 G3RCS9 ZNF394 PTHR23226:SF3 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 394 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000036543.1|UniProtKB=A0A2I2ZYG7 A0A2I2ZYG7 PTHR14191:SF20 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF4 protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling receptor binding#GO:0005102;binding#GO:0005488 protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;cellular process#GO:0009987;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008358.3|UniProtKB=G3QZ67 G3QZ67 EOMES PTHR11267:SF13 T-BOX PROTEIN-RELATED EOMESODERMIN HOMOLOG DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 T cell differentiation#GO:0030217;T cell activation involved in immune response#GO:0002286;endoderm formation#GO:0001706;embryo development#GO:0009790;lymphocyte activation#GO:0046649;lymphocyte activation involved in immune response#GO:0002285;cellular process#GO:0009987;endoderm development#GO:0007492;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;mesoderm development#GO:0007498;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;cell fate specification#GO:0001708;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;mononuclear cell differentiation#GO:1903131;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;gastrulation#GO:0007369;cell fate commitment#GO:0045165;cell activation involved in immune response#GO:0002263;formation of primary germ layer#GO:0001704;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;hemopoiesis#GO:0030097;mesoderm formation#GO:0001707;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;multicellular organismal process#GO:0032501;immune response#GO:0006955;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mesoderm morphogenesis#GO:0048332;leukocyte activation#GO:0045321;regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 GORGO|Ensembl=ENSGGOG00000016865.3|UniProtKB=G3RL21 G3RL21 LOC101147326 PTHR12532:SF12 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013218.3|UniProtKB=G3RBN2 G3RBN2 TMEM200A PTHR31815:SF0 AGAP005329-PA TRANSMEMBRANE PROTEIN 200A GORGO|Ensembl=ENSGGOG00000010293.3|UniProtKB=G3R459 G3R459 HMGCS2 PTHR43323:SF1 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE HYDROXYMETHYLGLUTARYL-COA SYNTHASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;acetyl-CoA metabolic process#GO:0006084;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000007090.3|UniProtKB=G3QVZ7 G3QVZ7 ICA1 PTHR10164:SF3 ISLET CELL AUTOANTIGEN 1 ISLET CELL AUTOANTIGEN 1 molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840;regulation of secretion#GO:0051046;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;biological regulation#GO:0065007;membrane organization#GO:0061024 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;vesicle#GO:0031982;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000006785.3|UniProtKB=G3QV77 G3QV77 PABPC1 PTHR24012:SF409 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1 mRNA 3'-UTR binding#GO:0003730;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000000983.3|UniProtKB=G3QFA1 G3QFA1 ARL6IP5 PTHR12859:SF2 PRA1 PROTEIN PRA1 FAMILY PROTEIN 3 negative regulation of transport#GO:0051051;regulation of transport#GO:0051049;regulation of localization#GO:0032879;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 membrane#GO:0016020;cellular anatomical structure#GO:0110165 amino acid transporter#PC00046;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015615.3|UniProtKB=G3RHW3 G3RHW3 CAPN13 PTHR10183:SF333 CALPAIN CALPAIN-13 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000028227.2|UniProtKB=G3RUC9 G3RUC9 EXOSC9 PTHR11097:SF14 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP45 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;snRNA 3'-end processing#GO:0034472;maturation of 5.8S rRNA#GO:0000460;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nuclear mRNA surveillance#GO:0071028;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;rRNA processing#GO:0006364;snRNA metabolic process#GO:0016073 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000015842.3|UniProtKB=A0A2I2ZUK5 A0A2I2ZUK5 ERCC2 PTHR11472:SF1 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;damaged DNA binding#GO:0003684;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;response to stimulus#GO:0050896;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;gene expression#GO:0010467 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA helicase#PC00011;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000012648.3|UniProtKB=A0A2I2ZQ14 A0A2I2ZQ14 KCNH7 PTHR10217:SF466 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED INWARDLY RECTIFYING POTASSIUM CHANNEL KCNH7 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267 transport#GO:0006810;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010332.3|UniProtKB=G3R492 G3R492 VNN2 PTHR10609:SF15 BIOTINIDASE-RELATED PANTETHEINE HYDROLASE VNN2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;metabolic process#GO:0008152;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000012439.3|UniProtKB=G3R9P6 G3R9P6 MSANTD2 PTHR46933:SF1 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000039334.1|UniProtKB=A0A2I2Z414 A0A2I2Z414 ZNF573 PTHR24381:SF425 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 626 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000023774.2|UniProtKB=G3RXR3 G3RXR3 QTRT1 PTHR43530:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000000367.3|UniProtKB=G3QDN5 G3QDN5 FNDC8 PTHR32430:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 8 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 8 GORGO|Ensembl=ENSGGOG00000043398.1|UniProtKB=A0A2I2YD29 A0A2I2YD29 PTHR24073:SF1083 DRAB5-RELATED RAB1A, MEMBER RAS ONCOGENE FAMILY hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;organelle assembly#GO:0070925;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000010967.3|UniProtKB=G3R5W6 G3R5W6 FANCA PTHR12047:SF2 FANCONI ANEMIA GROUP A PROTEIN FANCONI ANEMIA GROUP A PROTEIN regulation of hemopoiesis#GO:1903706;regulation of cell differentiation#GO:0045595;regulation of immune system process#GO:0002682;regulation of T cell activation#GO:0050863;regulation of cellular process#GO:0050794;regulation of lymphocyte activation#GO:0051249;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of leukocyte activation#GO:0002694;regulation of multicellular organismal development#GO:2000026;regulation of cell activation#GO:0050865;regulation of cell development#GO:0060284;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;Fanconi anaemia nuclear complex#GO:0043240 GORGO|Ensembl=ENSGGOG00000002730.3|UniProtKB=G3QJT7 G3QJT7 ASIC4 PTHR11690:SF13 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 4 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000041541.1|UniProtKB=A0A2I2YIF9 A0A2I2YIF9 MAGOHB PTHR12638:SF1 PROTEIN MAGO NASHI HOMOLOG PROTEIN MAGO NASHI HOMOLOG 2 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;nuclear mRNA surveillance#GO:0071028;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000027473.2|UniProtKB=G3S006 G3S006 TATDN3 PTHR46317:SF7 HYDROLASE OF PHP SUPERFAMILY-RELATED PROTEIN DEOXYRIBONUCLEASE TATDN3 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000036261.1|UniProtKB=A0A2I2Z4L7 A0A2I2Z4L7 SP6 PTHR23235:SF23 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000042990.1|UniProtKB=G3QVJ4 G3QVJ4 SPIB PTHR11849:SF174 ETS TRANSCRIPTION FACTOR SPI-B DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000011044.3|UniProtKB=A0A2I2Y268 A0A2I2Y268 TOR2A PTHR10760:SF4 TORSIN TORSIN-2A organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 GORGO|Ensembl=ENSGGOG00000038780.1|UniProtKB=A0A2I2Z4P9 A0A2I2Z4P9 KCNJ15 PTHR11767:SF20 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 15 voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;transport#GO:0006810;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000011817.4|UniProtKB=G3R825 G3R825 EHD4 PTHR11216:SF57 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;organelle assembly#GO:0070925;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;endocytosis#GO:0006897;protein localization to membrane#GO:0072657;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085 membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;recycling endosome#GO:0055037;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015584.3|UniProtKB=A0A2I2Y9X5 A0A2I2Y9X5 MED12L PTHR46007:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12-LIKE PROTEIN transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604 intracellular organelle#GO:0043229;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000004517.3|UniProtKB=G3QPE0 G3QPE0 UBN2 PTHR21669:SF10 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS UBINUCLEIN-2 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015456.3|UniProtKB=G3RHF7 G3RHF7 CA10 PTHR18952:SF91 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN 10 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000012720.3|UniProtKB=G3RAD0 G3RAD0 PTHR24246:SF47 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A2A transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled adenosine receptor signaling pathway#GO:0001973;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signal transduction#GO:0007165;synaptic transmission, dopaminergic#GO:0001963;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000012256.3|UniProtKB=G3R974 G3R974 BAD PTHR28540:SF1 BCL2-ASSOCIATED AGONIST OF CELL DEATH BCL2-ASSOCIATED AGONIST OF CELL DEATH enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;endopeptidase regulator activity#GO:0061135;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134 programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;apoptotic signaling pathway#GO:0097190;positive regulation of apoptotic process#GO:0043065 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 CCKR signaling map#P06959>BAD#P07210 GORGO|Ensembl=ENSGGOG00000042768.1|UniProtKB=A0A2I2ZCS2 A0A2I2ZCS2 GNG7 PTHR13809:SF8 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-7 ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 catalytic complex#GO:1902494;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Enkephalin release#P05913>G-Protein (s)#P05977;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Wnt signaling pathway#P00057>Ggamma#P01465 GORGO|Ensembl=ENSGGOG00000010637.3|UniProtKB=G3R510 G3R510 DHX32 PTHR18934:SF88 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX32-RELATED macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000002914.3|UniProtKB=G3QK94 G3QK94 INA PTHR45652:SF18 GLIAL FIBRILLARY ACIDIC PROTEIN ALPHA-INTERNEXIN structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;postsynapse#GO:0098794;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000034890.2|UniProtKB=G3SKG9 G3SKG9 ADAMTS18 PTHR13723:SF167 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 18 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000002736.3|UniProtKB=G3QJT9 G3QJT9 CHPF PTHR12369:SF22 CHONDROITIN SYNTHASE CHONDROITIN POLYMERIZING FACTOR, NON-CATALYTIC SUBUNIT catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;protein complex scaffold activity#GO:0140378;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000027217.2|UniProtKB=A0A2I2YLG1 A0A2I2YLG1 PTHR10836:SF111 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 GORGO|Ensembl=ENSGGOG00000042478.1|UniProtKB=A0A2I2YTY2 A0A2I2YTY2 PTHR23324:SF41 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 6 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000004440.3|UniProtKB=G3QP67 G3QP67 PTHR20437:SF5 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 13/17 SUBFAMILY NOT NAMED transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001840.3|UniProtKB=A0A2I2ZNM7 A0A2I2ZNM7 CTNNB1 PTHR45976:SF4 ARMADILLO SEGMENT POLARITY PROTEIN CATENIN BETA-1 protein phosphatase binding#GO:0019903;transcription coactivator activity#GO:0003713;cell adhesion molecule binding#GO:0050839;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cell adhesion#GO:0007155;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522 extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;adherens junction#GO:0005912;cell-cell junction#GO:0005911;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 p53 pathway feedback loops 2#P04398>beta-catenin#P04670;CCKR signaling map#P06959>beta-catenin#P07150;Gonadotropin-releasing hormone receptor pathway#P06664>CTNNB1#P06838;Cadherin signaling pathway#P00012>betacatenin#P00463;Wnt signaling pathway#P00057>Beta-Catenin#P01432;Angiogenesis#P00005>beta catenin#P00187;Alzheimer disease-presenilin pathway#P00004>beta-catenin#P00156 GORGO|Ensembl=ENSGGOG00000012323.3|UniProtKB=G3R9E6 G3R9E6 ETNPPL PTHR45688:SF1 FAMILY NOT NAMED ETHANOLAMINE-PHOSPHATE PHOSPHO-LYASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 GORGO|Ensembl=ENSGGOG00000009565.3|UniProtKB=G3R299 G3R299 TEX261 PTHR13144:SF0 TEX261 PROTEIN PROTEIN TEX261 cargo receptor activity#GO:0038024 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134 GORGO|Ensembl=ENSGGOG00000000063.3|UniProtKB=G3RRB1 G3RRB1 CCNG2 PTHR10177:SF60 CYCLINS CYCLIN-G2 cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000007714.3|UniProtKB=G3QXJ9 G3QXJ9 CSNK1G2 PTHR11909:SF157 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 GORGO|Ensembl=ENSGGOG00000000718.3|UniProtKB=G3S2A4 G3S2A4 IFRD1 PTHR12354:SF6 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000028523.3|UniProtKB=G3S8H9 G3S8H9 RB1CC1 PTHR13222:SF5 RB1-INDUCIBLE COILED-COIL RB1-INDUCIBLE COILED-COIL PROTEIN 1 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;macroautophagy#GO:0016236;reticulophagy#GO:0061709;glycogen catabolic process#GO:0005980;energy derivation by oxidation of organic compounds#GO:0015980;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;piecemeal microautophagy of the nucleus#GO:0034727;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex#GO:1990234;catalytic complex#GO:1902494;phagophore assembly site#GO:0000407;transferase complex, transferring phosphorus-containing groups#GO:0061695 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039359.1|UniProtKB=A0A2I2ZHT8 A0A2I2ZHT8 PTHR28592:SF4 ARMADILLO REPEAT-CONTAINING PROTEIN 1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000006121.3|UniProtKB=G3QTG7 G3QTG7 ZFP1 PTHR24377:SF248 IP01015P-RELATED ZINC FINGER PROTEIN 1 HOMOLOG transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011737.3|UniProtKB=G3QDN8 G3QDN8 PTHR10728:SF32 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 BETA cation binding#GO:0043169;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;small molecule binding#GO:0036094;lipase activity#GO:0016298;ion binding#GO:0043167;hydrolase activity, acting on ester bonds#GO:0016788;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;lipid binding#GO:0008289;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620 lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 phospholipase#PC00186 VEGF signaling pathway#P00056>cPLA2#P01409;Angiogenesis#P00005>PLA2#P00227;Oxidative stress response#P00046>cPLA2#P01134;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLA2#P00855;Angiogenesis#P00005>cPLA2#P00251 GORGO|Ensembl=ENSGGOG00000002570.3|UniProtKB=G3QJE1 G3QJE1 ARMC9 PTHR14881:SF4 LISH DOMAIN-CONTAINING PROTEIN ARMC9 LISH DOMAIN-CONTAINING PROTEIN ARMC9 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000036343.1|UniProtKB=A0A2I2YSN4 A0A2I2YSN4 PTHR45616:SF42 GATA-TYPE DOMAIN-CONTAINING PROTEIN IF ROD DOMAIN-CONTAINING PROTEIN anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000006137.3|UniProtKB=G3RMQ0 G3RMQ0 PTHR10794:SF50 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PHOSPHOLIPASE ABHD3 phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;phospholipid metabolic process#GO:0006644;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000010573.3|UniProtKB=G3R4U6 G3R4U6 CXCL10 PTHR12015:SF188 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 10 binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;neutrophil chemotaxis#GO:0030593;response to chemical#GO:0042221;neutrophil migration#GO:1990266;response to cytokine#GO:0034097;taxis#GO:0042330;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;granulocyte migration#GO:0097530;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;cell chemotaxis#GO:0060326;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;chemotaxis#GO:0006935;inflammatory response#GO:0006954;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;response to external biotic stimulus#GO:0043207;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;cellular response to molecule of bacterial origin#GO:0071219;leukocyte migration#GO:0050900;biological regulation#GO:0065007;response to other organism#GO:0051707;cell migration#GO:0016477 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000004043.3|UniProtKB=G3QN65 G3QN65 VWCE PTHR47333:SF1 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;response to virus#GO:0009615;response to biotic stimulus#GO:0009607 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015971.3|UniProtKB=G3RIR3 G3RIR3 PARP9 PTHR14453:SF70 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP9 glycosyltransferase activity#GO:0016757;ubiquitin-like protein ligase binding#GO:0044389;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;protein binding#GO:0005515;binding#GO:0005488;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;pentosyltransferase activity#GO:0016763 regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;positive regulation of signal transduction#GO:0009967;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cytokine-mediated signaling pathway#GO:0001961;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of cytokine-mediated signaling pathway#GO:0001959;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;regulation of response to cytokine stimulus#GO:0060759;positive regulation of immune system process#GO:0002684;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000006016.3|UniProtKB=G3QT82 G3QT82 GMIP PTHR15228:SF16 SPERMATHECAL PHYSIOLOGY VARIANT GEM-INTERACTING PROTEIN enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;intracellular signal transduction#GO:0035556;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;cellular process#GO:0009987 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000026268.2|UniProtKB=G3SDF0 G3SDF0 NIPBL PTHR21704:SF19 NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED NIPPED-B-LIKE PROTEIN chromatin binding#GO:0003682;binding#GO:0005488 establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;DNA repair#GO:0006281;DNA damage response#GO:0006974;developmental process#GO:0032502;mitotic sister chromatid cohesion#GO:0007064;brain development#GO:0007420;multicellular organismal process#GO:0032501;nucleobase-containing compound metabolic process#GO:0006139;tube development#GO:0035295;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;skeletal system morphogenesis#GO:0048705;localization#GO:0051179;sister chromatid cohesion#GO:0007062;anatomical structure development#GO:0048856;system development#GO:0048731;recombinational repair#GO:0000725;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;mitotic cell cycle#GO:0000278;animal organ morphogenesis#GO:0009887;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;heart morphogenesis#GO:0003007;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;heart development#GO:0007507;head development#GO:0060322;nervous system development#GO:0007399;embryo development#GO:0009790;organelle organization#GO:0006996;response to stress#GO:0006950;establishment of protein localization#GO:0045184;cellular process#GO:0009987;skeletal system development#GO:0001501;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;central nervous system development#GO:0007417;circulatory system development#GO:0072359;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000023823.2|UniProtKB=G3SH48 G3SH48 ELFN1 PTHR24373:SF288 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN PROTEIN ELFN1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037738.1|UniProtKB=A0A2I2ZS13 A0A2I2ZS13 YPEL PTHR13848:SF3 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 2 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000023191.2|UniProtKB=G3S8X7 G3S8X7 PTHR10155:SF32 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 6 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 kinase modulator#PC00140 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879;Interferon-gamma signaling pathway#P00035>SOCS#P00956 GORGO|Ensembl=ENSGGOG00000002059.3|UniProtKB=G3QI31 G3QI31 MDH1B PTHR23382:SF1 MALATE DEHYDROGENASE MALATE DEHYDROGENASE 1B-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;oxoacid metabolic process#GO:0043436;pyridine-containing compound metabolic process#GO:0072524 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000001138.3|UniProtKB=G3QFP4 G3QFP4 NIM1K PTHR24346:SF49 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE NIM1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000017072.3|UniProtKB=G3RLL0 G3RLL0 HNRNPA2B1 PTHR48026:SF13 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2_B1 telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;mRNA 3'-UTR binding#GO:0003730;DNA binding#GO:0003677;RNA binding#GO:0003723;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;RNA biosynthetic process#GO:0032774;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;nucleic acid transport#GO:0050657;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;localization#GO:0051179 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000007426.3|UniProtKB=G3QWU7 G3QWU7 MINPP1 PTHR20963:SF57 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000007207.3|UniProtKB=G3QW96 G3QW96 LOC101141197 PTHR26450:SF142 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56B4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016212.3|UniProtKB=G3RJD0 G3RJD0 CSF1 PTHR10058:SF0 MACROPHAGE COLONY STIMULATING FACTOR MACROPHAGE COLONY-STIMULATING FACTOR 1 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 leukocyte differentiation#GO:0002521;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;myeloid cell differentiation#GO:0030099;regulation of immune system process#GO:0002682;regulation of developmental process#GO:0050793;cell development#GO:0048468;regulation of myeloid cell differentiation#GO:0045637;regulation of hemopoiesis#GO:1903706;anatomical structure development#GO:0048856;osteoclast differentiation#GO:0030316;positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of myeloid cell differentiation#GO:0045639;cellular process#GO:0009987;regulation of cell development#GO:0060284;hemopoiesis#GO:0030097;biological regulation#GO:0065007;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;cellular developmental process#GO:0048869 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005756.3|UniProtKB=G3QSJ5 G3QSJ5 LOC101146971 PTHR12767:SF10 BCL7 RELATED B-CELL CLL_LYMPHOMA 7 PROTEIN FAMILY MEMBER C cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ATPase complex#GO:1904949;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000025829.2|UniProtKB=A0A2I2ZJG7 A0A2I2ZJG7 HADHB PTHR18919:SF147 ACETYL-COA C-ACYLTRANSFERASE TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000026534.2|UniProtKB=G3SCP3 G3SCP3 TMEM119 PTHR28645:SF1 TRANSMEMBRANE PROTEIN 119 TRANSMEMBRANE PROTEIN 119 regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;regulation of cell population proliferation#GO:0042127;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of cell population proliferation#GO:0008284;regulation of multicellular organismal process#GO:0051239;regulation of bone mineralization#GO:0030500;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000000794.3|UniProtKB=A0A2I2YF60 A0A2I2YF60 RPL38 PTHR10965:SF0 60S RIBOSOMAL PROTEIN L38 LARGE RIBOSOMAL SUBUNIT PROTEIN EL38 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000044031.1|UniProtKB=G3SBZ0 G3SBZ0 LOC101130037 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;regulation of protein stability#GO:0031647;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000002206.3|UniProtKB=G3QIG2 G3QIG2 TBKBP1 PTHR14432:SF2 PROSAPIP2 PROTEIN/5-AZACYTIDINE INDUCED GENE 2 TANK-BINDING KINASE 1-BINDING PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000003549.3|UniProtKB=G3QLW3 G3QLW3 PTHR11736:SF145 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B16 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016116.3|UniProtKB=G3RJ46 G3RJ46 LOC101146547 PTHR24329:SF567 HOMEOBOX PROTEIN ARISTALESS RHOX HOMEOBOX FAMILY MEMBER 2-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000013076.3|UniProtKB=G3RZC3 G3RZC3 FBL PTHR10335:SF4 RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN RRNA 2'-O-METHYLTRANSFERASE FIBRILLARIN S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;nucleic acid binding#GO:0003676;N-methyltransferase activity#GO:0008170;RNA binding#GO:0003723;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;rRNA methyltransferase activity#GO:0008649;methyltransferase activity#GO:0008168;binding#GO:0005488;histone methyltransferase activity#GO:0042054;histone modifying activity#GO:0140993;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;rRNA methylation#GO:0031167;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000040129.1|UniProtKB=A0A2I2Y8H2 A0A2I2Y8H2 FITM2 PTHR23129:SF1 ACYL-COENZYME A DIPHOSPHATASE FITM2 ACYL-COENZYME A DIPHOSPHATASE FITM2 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 chemical homeostasis#GO:0048878;organelle assembly#GO:0070925;lipid droplet organization#GO:0034389;cellular component organization or biogenesis#GO:0071840;lipid storage#GO:0019915;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membraneless organelle assembly#GO:0140694;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;homeostatic process#GO:0042592;cellular component assembly#GO:0022607 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000011762.3|UniProtKB=G3R7X2 G3R7X2 PRELID1 PTHR11158:SF31 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 phospholipid transport#GO:0015914;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;macromolecule localization#GO:0033036;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000010342.3|UniProtKB=G3R499 G3R499 MAGT1 PTHR12692:SF2 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT MAGT1 transport#GO:0006810;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;magnesium ion transport#GO:0015693;carbohydrate derivative biosynthetic process#GO:1901137;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;monoatomic ion transmembrane transport#GO:0034220;biosynthetic process#GO:0009058;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;protein metabolic process#GO:0019538;monoatomic cation transport#GO:0006812;localization#GO:0051179;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;metal ion transport#GO:0030001 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000015430.3|UniProtKB=G3RHD5 G3RHD5 LZTS2 PTHR19354:SF4 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 2-RELATED regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 GORGO|Ensembl=ENSGGOG00000027335.2|UniProtKB=G3SIG2 G3SIG2 MARVELD1 PTHR22776:SF28 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002350.3|UniProtKB=G3QIU5 G3QIU5 SNRPD2 PTHR12777:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;spliceosomal snRNP assembly#GO:0000387;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 U2 snRNP#GO:0005686;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytoplasm#GO:0005737;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000006069.2|UniProtKB=G3QTC2 G3QTC2 ZNF589 PTHR24381:SF343 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 589 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000014899.3|UniProtKB=G3RG02 G3RG02 C3AR1 PTHR24225:SF28 CHEMOTACTIC RECEPTOR C3A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of biological quality#GO:0065008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000005653.3|UniProtKB=G3RWG5 G3RWG5 ALPI PTHR11596:SF30 ALKALINE PHOSPHATASE INTESTINAL-TYPE ALKALINE PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000000269.3|UniProtKB=A0A2K5TIZ2 A0A2K5TIZ2 TAS2R38 PTHR11394:SF52 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 38 transmembrane signaling receptor activity#GO:0004888;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089 sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000024725.2|UniProtKB=G3RU06 G3RU06 RPS28 PTHR10769:SF3 40S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN ES28 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006298.3|UniProtKB=A0A2I2Y937 A0A2I2Y937 PTPRB PTHR46957:SF2 CYTOKINE RECEPTOR RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE BETA cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;blood vessel morphogenesis#GO:0048514;tube development#GO:0035295;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501 protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VE-PTP#P00250 GORGO|Ensembl=ENSGGOG00000036134.1|UniProtKB=A0A2I2YAQ9 A0A2I2YAQ9 PTHR24070:SF452 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAP1A catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of neurotransmitter secretion#GO:0046928;response to stimulus#GO:0050896;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;regulation of neurotransmitter transport#GO:0051588;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of secretion by cell#GO:1903530;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of exocytosis#GO:0017157;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cellular response to nitrogen compound#GO:1901699;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000023493.2|UniProtKB=G3RQX9 G3RQX9 IAPP PTHR10505:SF4 CALCITONIN-RELATED ISLET AMYLOID POLYPEPTIDE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000008998.3|UniProtKB=G3R0U9 G3R0U9 GARIN3 PTHR22574:SF2 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 3 GORGO|Ensembl=ENSGGOG00000005688.3|UniProtKB=G3QSD5 G3QSD5 CFAP141 PTHR35818:SF1 C1ORF189 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 141 GORGO|Ensembl=ENSGGOG00000027580.2|UniProtKB=G3S1S8 G3S1S8 NPC1L1 PTHR45727:SF3 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC1-LIKE INTRACELLULAR CHOLESTEROL TRANSPORTER 1 sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;cholesterol binding#GO:0015485;steroid binding#GO:0005496;alcohol binding#GO:0043178 lipid transport#GO:0006869;digestion#GO:0007586;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;macromolecule localization#GO:0033036;lipid homeostasis#GO:0055088;localization#GO:0051179;cholesterol homeostasis#GO:0042632;establishment of localization#GO:0051234;sterol transport#GO:0015918;organic hydroxy compound transport#GO:0015850;system process#GO:0003008;lipid localization#GO:0010876;chemical homeostasis#GO:0048878;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000007718.3|UniProtKB=A0A2I2ZKH7 A0A2I2ZKH7 LOC101141032 PTHR24225:SF27 CHEMOTACTIC RECEPTOR G PROTEIN-COUPLED RECEPTOR 32-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000010821.3|UniProtKB=G3R5H2 G3R5H2 POLR2L PTHR23431:SF11 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;catalytic activity, acting on RNA#GO:0140098;zinc ion binding#GO:0008270;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription by RNA polymerase I#GO:0006360;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 DNA metabolism protein#PC00009 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 GORGO|Ensembl=ENSGGOG00000011664.3|UniProtKB=A0A2I2ZA54 A0A2I2ZA54 ABI1 PTHR10460:SF2 ABL INTERACTOR FAMILY MEMBER ABL INTERACTOR 1 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 nervous system development#GO:0007399;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron migration#GO:0001764;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell motility#GO:0048870;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cell leading edge#GO:0031252;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;organelle#GO:0043226;lamellipodium#GO:0030027;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007712.3|UniProtKB=G3QXJ8 G3QXJ8 RSPO1 PTHR46987:SF5 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000006447.3|UniProtKB=G3SIT0 G3SIT0 DCLK1 PTHR24347:SF401 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;developmental growth involved in morphogenesis#GO:0060560;neuron projection extension#GO:1990138;neuron development#GO:0048666;cellular process#GO:0009987;neuron projection development#GO:0031175;axon extension#GO:0048675;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell growth#GO:0016049;developmental cell growth#GO:0048588;system development#GO:0048731;anatomical structure development#GO:0048856;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;developmental growth#GO:0048589;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000007144.3|UniProtKB=G3QW50 G3QW50 PTHR23182:SF3 BREAKPOINT CLUSTER REGION PROTEIN BCR BREAKPOINT CLUSTER REGION PROTEIN enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of small GTPase mediated signal transduction#GO:0051056 cell junction#GO:0030054;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944 G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000010011.3|UniProtKB=G3R3E1 G3R3E1 PTPRCAP PTHR15312:SF1 PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE C-ASSOCIATED PROTEIN PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE C-ASSOCIATED PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000016451.3|UniProtKB=G3RJZ3 G3RJZ3 RTP5 PTHR14402:SF2 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 5 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cellular component organization or biogenesis#GO:0071840;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;establishment of localization#GO:0051234;system process#GO:0003008;intracellular protein localization#GO:0008104;sensory perception of taste#GO:0050909;protein targeting to membrane#GO:0006612;sensory perception of chemical stimulus#GO:0007606;protein insertion into membrane#GO:0051205;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;membrane organization#GO:0061024;detection of stimulus involved in sensory perception#GO:0050906;macromolecule localization#GO:0033036;detection of stimulus#GO:0051606;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;detection of chemical stimulus involved in sensory perception#GO:0050907;localization within membrane#GO:0051668;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;response to stimulus#GO:0050896;protein targeting#GO:0006605;cellular component organization#GO:0016043;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000039881.1|UniProtKB=A0A2I2YLB6 A0A2I2YLB6 RPL39L PTHR19970:SF22 RIBOSOMAL PROTEIN L39E RIBOSOMAL PROTEIN EL39-LIKE 2 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;spermatogenesis#GO:0007283;developmental process#GO:0032502;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;male gamete generation#GO:0048232;biosynthetic process#GO:0009058;sexual reproduction#GO:0019953;translation#GO:0006412;protein metabolic process#GO:0019538;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;cytoplasmic translation#GO:0002181;gamete generation#GO:0007276;protein biosynthetic process#GO:0160307;reproductive process#GO:0022414 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001443.3|UniProtKB=A0A2I2ZYU0 A0A2I2ZYU0 SPHK2 PTHR12358:SF40 SPHINGOSINE KINASE SPHINGOSINE KINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;regulation of apoptotic process#GO:0042981;lipid metabolic process#GO:0006629;positive regulation of apoptotic process#GO:0043065;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;sphingoid biosynthetic process#GO:0046520;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;phospholipid metabolic process#GO:0006644 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 Angiogenesis#P00005>SPK#P00229;VEGF signaling pathway#P00056>SPK#P01404 GORGO|Ensembl=ENSGGOG00000004027.3|UniProtKB=G3QN47 G3QN47 CZIB PTHR12857:SF0 CXXC MOTIF CONTAINING ZINC BINDING PROTEIN CXXC MOTIF CONTAINING ZINC BINDING PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;zinc ion binding#GO:0008270;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 GORGO|Ensembl=ENSGGOG00000002117.3|UniProtKB=G3QI81 G3QI81 CTSC PTHR12411:SF1058 CYSTEINE PROTEASE FAMILY C1-RELATED DIPEPTIDYL PEPTIDASE 1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 extracellular region#GO:0005576;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000008708.3|UniProtKB=G3R040 G3R040 CFP PTHR22906:SF43 PROPERDIN PROPERDIN GORGO|Ensembl=ENSGGOG00000036948.1|UniProtKB=A0A2I2YIG3 A0A2I2YIG3 SMCO3 PTHR35972:SF1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000022043.2|UniProtKB=G3SBS2 G3SBS2 MAGEA9 PTHR11736:SF62 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 9 histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010504.3|UniProtKB=G3R4P0 G3R4P0 RIN1 PTHR23101:SF62 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR 1 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899 endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytosol#GO:0005829 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000041221.1|UniProtKB=A0A2I2ZF44 A0A2I2ZF44 PTHR26450:SF379 OLFACTORY RECEPTOR 56B1-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002939.3|UniProtKB=G3QKB7 G3QKB7 CCL19 PTHR12015:SF80 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 19 signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell surface receptor signaling pathway#GO:0007166;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;response to stress#GO:0006950;response to chemical#GO:0042221;response to cytokine#GO:0034097;taxis#GO:0042330;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;cell migration#GO:0016477;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cytokine-mediated signaling pathway#GO:0019221;cell chemotaxis#GO:0060326;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000037995.1|UniProtKB=A0A2I2YDV7 A0A2I2YDV7 PTHR13160:SF11 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000027813.2|UniProtKB=G3SJE4 G3SJE4 SLC17A3 PTHR11662:SF134 SOLUTE CARRIER FAMILY 17 SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 4 voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;efflux transmembrane transporter activity#GO:0015562;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;xenobiotic transmembrane transporter activity#GO:0042910;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 transport#GO:0006810;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000001392.3|UniProtKB=G3QGC1 G3QGC1 MAP3K10 PTHR23257:SF755 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000015982.3|UniProtKB=A0A2I2YRQ4 A0A2I2YRQ4 PCK2 PTHR11561:SF11 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE [GTP], MITOCHONDRIAL carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to steroid hormone#GO:0048545;anatomical structure development#GO:0048856;response to glucose#GO:0009749;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;response to peptide hormone#GO:0043434;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;cellular response to insulin stimulus#GO:0032869;cellular homeostasis#GO:0019725;liver development#GO:0001889;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;response to monosaccharide#GO:0034284;cellular response to chemical stimulus#GO:0070887;response to carbohydrate#GO:0009743;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;alcohol biosynthetic process#GO:0046165;cellular response to lipid#GO:0071396;carbohydrate biosynthetic process#GO:0016051;alcohol metabolic process#GO:0006066;cellular response to steroid hormone stimulus#GO:0071383;multicellular organism development#GO:0007275;glucose homeostasis#GO:0042593;response to starvation#GO:0042594;hexose biosynthetic process#GO:0019319;cellular response to peptide hormone stimulus#GO:0071375;carbohydrate metabolic process#GO:0005975;homeostatic process#GO:0042592;system development#GO:0048731;response to nitrogen compound#GO:1901698;response to nutrient levels#GO:0031667;cellular response to nitrogen compound#GO:1901699;tissue development#GO:0009888;small molecule biosynthetic process#GO:0044283;developmental process#GO:0032502;cellular developmental process#GO:0048869;intracellular chemical homeostasis#GO:0055082;carboxylic acid metabolic process#GO:0019752;response to hexose#GO:0009746;response to endogenous stimulus#GO:0009719;carbohydrate homeostasis#GO:0033500;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;intracellular glucose homeostasis#GO:0001678;response to hormone#GO:0009725;response to stress#GO:0006950;gluconeogenesis#GO:0006094;response to lipid#GO:0033993;response to chemical#GO:0042221;monosaccharide metabolic process#GO:0005996;cellular response to glucose stimulus#GO:0071333;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;animal organ development#GO:0048513;glucose metabolic process#GO:0006006 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000010656.3|UniProtKB=G3R542 G3R542 GUCY2C PTHR11920:SF347 GUANYLYL CYCLASE GUANYLYL CYCLASE C lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975 organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;cell communication#GO:0007154;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanylate cyclase#PC00114;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000011072.3|UniProtKB=A0A2I2YF74 A0A2I2YF74 PTHR10555:SF129 SORTING NEXIN SORTING NEXIN-1 ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;retromer complex#GO:0030904;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003759.3|UniProtKB=G3QMF1 G3QMF1 CDC42EP1 PTHR15344:SF7 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 1 protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488;enzyme binding#GO:0019899 positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of supramolecular fiber organization#GO:1902903;cellular response to stimulus#GO:0051716;regulation of developmental process#GO:0050793;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;positive regulation of cell projection organization#GO:0031346;regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;intracellular signaling cassette#GO:0141124;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;response to stimulus#GO:0050896;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;Rho protein signal transduction#GO:0007266 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013033.3|UniProtKB=A0A2I2Z3I0 A0A2I2Z3I0 BCKDHA PTHR43380:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000014323.3|UniProtKB=G3REJ7 G3REJ7 HDAC4 PTHR10625:SF33 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 4 histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824 epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000043869.1|UniProtKB=A0A2I2ZFF7 A0A2I2ZFF7 PTHR19367:SF36 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 9-1 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000013182.3|UniProtKB=G3RBK6 G3RBK6 MSI2 PTHR48032:SF10 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 RNA-BINDING PROTEIN MUSASHI HOMOLOG 2 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000037579.1|UniProtKB=A0A2I2Z0Q5 A0A2I2Z0Q5 LOC134758959 PTHR24264:SF64 TRYPSIN-RELATED TRYPSIN-6-RELATED catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000006031.3|UniProtKB=A0A2I2YRH7 A0A2I2YRH7 PLEKHA8 PTHR10219:SF111 GLYCOLIPID TRANSFER PROTEIN-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8 transporter activity#GO:0005215;phospholipid binding#GO:0005543;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;phospholipid transfer activity#GO:0120014;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 cellular localization#GO:0051641;localization#GO:0051179;lipid localization#GO:0010876;ceramide transport#GO:0035627;cellular component organization#GO:0016043;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular transport#GO:0046907;transport#GO:0006810;lipid transport#GO:0006869;membrane organization#GO:0061024;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000041717.1|UniProtKB=A0A2I2YHN8 A0A2I2YHN8 LOC101144326 PTHR23262:SF55 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 16-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000006816.3|UniProtKB=G3QV99 G3QV99 PTHR11309:SF34 FRIZZLED FRIZZLED-2 signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;non-canonical Wnt signaling pathway#GO:0035567;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Wnt signaling pathway#P00057>Frizzled#P01428;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 GORGO|Ensembl=ENSGGOG00000013495.3|UniProtKB=G3S990 G3S990 RNF10 PTHR12983:SF10 RING FINGER 10 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RNF10 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of nervous system development#GO:0051960;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of system process#GO:0044057;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;proteasomal protein catabolic process#GO:0010498 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000005004.3|UniProtKB=G3QQN7 G3QQN7 PGBD5 PTHR28576:SF2 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000001357.3|UniProtKB=G3QG86 G3QG86 KLK14 PTHR24271:SF48 KALLIKREIN-RELATED KALLIKREIN-14 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000010054.3|UniProtKB=A0A2I2YQ68 A0A2I2YQ68 FHL1 PTHR24205:SF14 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 1 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000004808.3|UniProtKB=G3QQ56 G3QQ56 ELP3 PTHR11135:SF0 HISTONE ACETYLTRANSFERASE-RELATED ELONGATOR COMPLEX PROTEIN 3 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;elongator holoenzyme complex#GO:0033588;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008521.3|UniProtKB=G3QZL7 G3QZL7 HES1 PTHR10985:SF153 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of neuron differentiation#GO:0045664;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cell communication#GO:0007154;pattern specification process#GO:0007389;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 GORGO|Ensembl=ENSGGOG00000005642.3|UniProtKB=G3QS97 G3QS97 KLHDC1 PTHR46228:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000008488.3|UniProtKB=G3QZI3 G3QZI3 HNF4G PTHR24083:SF42 NUCLEAR HORMONE RECEPTOR HEPATOCYTE NUCLEAR FACTOR 4-GAMMA transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000037460.1|UniProtKB=G3S958 G3S958 PTHR23267:SF407 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 2-14-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000012188.3|UniProtKB=G3R914 G3R914 MTHFS PTHR23407:SF1 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;tetrahydrofolate biosynthetic process#GO:0046654;tetrahydrofolate metabolic process#GO:0046653 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000022321.2|UniProtKB=G3SFP4 G3SFP4 NUS1 PTHR21528:SF3 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 catalytic activity#GO:0003824;transferase activity#GO:0016740;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;organophosphate metabolic process#GO:0019637;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000006986.3|UniProtKB=G3QVR2 G3QVR2 PCSK1 PTHR42884:SF39 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;proteolysis#GO:0006508;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein processing#GO:0016485;peptide hormone processing#GO:0016486;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;neuron projection#GO:0043005;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Endothelin signaling pathway#P00019>furin#P00575;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 GORGO|Ensembl=ENSGGOG00000017062.3|UniProtKB=G3RLK5 G3RLK5 RC3H2 PTHR13139:SF2 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN ROQUIN-2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA binding#GO:0003723;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;double-stranded RNA binding#GO:0003725;ubiquitin-like protein transferase activity#GO:0019787 regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA metabolic process#GO:0051252;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655 intracellular organelle#GO:0043229;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000025337.2|UniProtKB=G3S348 G3S348 LOC101128459 PTHR23260:SF3 KERATIN ASSOCIATED PROTEIN 3-3-RELATED KERATIN-ASSOCIATED PROTEIN 3-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000038140.1|UniProtKB=A0A2I2Z004 A0A2I2Z004 PTHR10768:SF21 60S RIBOSOMAL PROTEIN L37 60S RIBOSOMAL PROTEIN L37 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005382.3|UniProtKB=G3S4G7 G3S4G7 RSPO2 PTHR46987:SF4 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor serine/threonine kinase binding#GO:0033612;binding#GO:0005488 regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000001481.3|UniProtKB=G3QGK3 G3QGK3 TGFB3 PTHR11848:SF34 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-3 PROPROTEIN cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;multicellular organism development#GO:0007275;animal organ development#GO:0048513;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;biological regulation#GO:0065007;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;response to transforming growth factor beta#GO:0071559;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;circulatory system development#GO:0072359;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000037761.1|UniProtKB=A0A2I2YYD2 A0A2I2YYD2 HS6ST1 PTHR12812:SF1 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000015921.3|UniProtKB=G3RIM6 G3RIM6 IQUB PTHR21074:SF0 IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN IQ MOTIF AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN secretory vesicle#GO:0099503;endomembrane system#GO:0012505;cytoplasm#GO:0005737;acrosomal vesicle#GO:0001669;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000012781.3|UniProtKB=A0A2I2ZMF5 A0A2I2ZMF5 LRIT2 PTHR24366:SF39 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT, IG-LIKE AND TRANSMEMBRANE DOMAINS 2 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000016509.4|UniProtKB=A0A2I2Y9M5 A0A2I2Y9M5 ADGRL3 PTHR23192:SF75 OLFACTOMEDIN-RELATED ADHESION G PROTEIN-COUPLED RECEPTOR L3 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000042758.1|UniProtKB=A0A2I2YRF3 A0A2I2YRF3 FZD5 PTHR11309:SF136 FRIZZLED FRIZZLED-5 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;non-canonical Wnt signaling pathway#GO:0035567;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>Frizzled#P00475;Angiogenesis#P00005>Fzd#P00189;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428 GORGO|Ensembl=ENSGGOG00000011257.3|UniProtKB=G3R6L3 G3R6L3 ADM PTHR23414:SF3 ADRENOMEDULLIN, ADM PRO-ADRENOMEDULLIN binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;renal system process#GO:0003014;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of system process#GO:0044057;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;signaling#GO:0023052;regulation of heart contraction#GO:0008016;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of body fluid levels#GO:0050878;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000001681.3|UniProtKB=G3QH35 G3QH35 PDCD1LG2 PTHR25466:SF1 T-LYMPHOCYTE ACTIVATION ANTIGEN PROGRAMMED CELL DEATH 1 LIGAND 2 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;negative regulation of cell communication#GO:0010648;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000015609.3|UniProtKB=G3RHU9 G3RHU9 BAAT PTHR10824:SF18 ACYL-COENZYME A THIOESTERASE-RELATED BILE ACID-COA:AMINO ACID N-ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;deacylase activity#GO:0160215;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;acyltransferase activity#GO:0016746;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;thiolester hydrolase activity#GO:0016790 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;steroid metabolic process#GO:0008202;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753 microbody#GO:0042579;peroxisome#GO:0005777;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000002552.3|UniProtKB=G3QJD0 G3QJD0 SORL1 PTHR12106:SF50 SORTILIN RELATED SORTILIN-RELATED RECEPTOR establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein localization to Golgi apparatus#GO:0034067;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;lysosomal transport#GO:0007041;protein localization to vacuole#GO:0072665;protein localization to organelle#GO:0033365;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;protein localization to lysosome#GO:0061462 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000014080.3|UniProtKB=G3RDX2 G3RDX2 COL26A1 PTHR15427:SF19 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COLLAGEN ALPHA-1(XXVI) CHAIN positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of cell adhesion#GO:0045785;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001351.3|UniProtKB=G3QG82 G3QG82 LOC101139006 PTHR26450:SF40 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004025.3|UniProtKB=G3QN45 G3QN45 SDR16C5 PTHR24322:SF728 PKSB EPIDERMAL RETINOL DEHYDROGENASE 2 all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008 intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000010650.3|UniProtKB=A0A2I2YNT0 A0A2I2YNT0 AMZ2 PTHR32205:SF5 ARCHAEMETZINCIN-2-RELATED ARCHAEMETZINCIN-2 GORGO|Ensembl=ENSGGOG00000017099.3|UniProtKB=G3RLN3 G3RLN3 LRRC43 PTHR45973:SF35 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 43 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000007167.3|UniProtKB=G3SIT4 G3SIT4 LIF PTHR10633:SF0 LEUKEMIA INHIBITORY FACTOR LEUKEMIA INHIBITORY FACTOR protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;regulation of cell differentiation#GO:0045595;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000013069.3|UniProtKB=G3RIJ5 G3RIJ5 MTSS2 PTHR15708:SF8 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED PROTEIN MTSS 2 phospholipid binding#GO:0005543;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;lipid binding#GO:0008289 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000007201.3|UniProtKB=G3QWB2 G3QWB2 DYSF PTHR12546:SF44 FER-1-LIKE DYSFERLIN membrane organization#GO:0061024;endomembrane system organization#GO:0010256;response to stress#GO:0006950;response to wounding#GO:0009611;membrane fusion#GO:0061025;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;muscle structure development#GO:0061061;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;cellular component organization#GO:0016043;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;anatomical structure development#GO:0048856;plasma membrane organization#GO:0007009;wound healing#GO:0042060;animal gross anatomical part developmental process#GO:0160108 sarcolemma#GO:0042383;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000004605.3|UniProtKB=G3QPL6 G3QPL6 OR10A4 PTHR26453:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002557.3|UniProtKB=G3QJC6 G3QJC6 DKK1 PTHR12113:SF11 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 1 signaling receptor regulator activity#GO:0030545;binding#GO:0005488;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;protein binding#GO:0005515 regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000039358.1|UniProtKB=A0A2I2Y3N5 A0A2I2Y3N5 MRPS17 PTHR24088:SF2 28S RIBOSOMAL PROTEIN S17, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US17M mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000023074.2|UniProtKB=G3SIT3 G3SIT3 GRIPAP1 PTHR18978:SF1 GRIP-1 ASSOCIATED PROTEIN 1 GRIP1-ASSOCIATED PROTEIN 1 regulation of protein localization to membrane#GO:1905475;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;biological regulation#GO:0065007;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of establishment of protein localization#GO:0070201;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;glutamatergic synapse#GO:0098978;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;presynapse#GO:0098793;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;synaptic membrane#GO:0097060;early endosome membrane#GO:0031901 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000025643.2|UniProtKB=G3RYK4 G3RYK4 URB2 PTHR15682:SF2 UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000022874.2|UniProtKB=G3RQU5 G3RQU5 CNRIP1 PTHR31952:SF1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000006999.3|UniProtKB=G3QVS0 G3QVS0 PDE3B PTHR11347:SF29 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000014679.3|UniProtKB=G3RFF5 G3RFF5 CXHXorf65 PTHR33887:SF4 PB1 DOMAIN-CONTAINING PROTEIN CHROMOSOME X OPEN READING FRAME 65 GORGO|Ensembl=ENSGGOG00000006855.3|UniProtKB=G3S2X0 G3S2X0 VIRMA PTHR23185:SF0 PROTEIN VIRILIZER HOMOLOG PROTEIN VIRILIZER HOMOLOG intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;methyltransferase complex#GO:0034708;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000013918.3|UniProtKB=G3RDG8 G3RDG8 EFNA3 PTHR11304:SF5 EPHRIN EPHRIN-A3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000027433.2|UniProtKB=G3SGY4 G3SGY4 DUS3L PTHR45846:SF1 TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000011609.3|UniProtKB=G3R7I4 G3R7I4 RPL24 PTHR10792:SF44 60S RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN EL24 RNA binding#GO:0003723;structural molecule activity#GO:0005198;mRNA binding#GO:0003729;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000022162.2|UniProtKB=G3RRL8 G3RRL8 LY6G6C PTHR32149:SF2 LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6C LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6C GORGO|Ensembl=ENSGGOG00000017016.3|UniProtKB=G3RLG2 G3RLG2 TRMT11 PTHR13370:SF3 RNA METHYLASE-RELATED TRNA (GUANINE(10)-N(2))-METHYLTRANSFERASE TRMT11 transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014894.3|UniProtKB=G3R9Z5 G3R9Z5 LCORL PTHR21545:SF10 TRANSCRIPTION FACTOR MLR1/2 LIGAND-DEPENDENT NUCLEAR RECEPTOR COREPRESSOR-LIKE PROTEIN regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000009066.4|UniProtKB=G3R116 G3R116 CHCHD6 PTHR47609:SF1 MICOS COMPLEX SUBUNIT MIC25 MICOS COMPLEX SUBUNIT MIC25 mitochondrion organization#GO:0007005;membrane organization#GO:0061024;response to stimulus#GO:0050896;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;organelle organization#GO:0006996;cellular component organization#GO:0016043;response to stress#GO:0006950;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007975.3|UniProtKB=G3QY73 G3QY73 LIMA1 PTHR24206:SF57 OS06G0237300 PROTEIN LIM DOMAIN AND ACTIN-BINDING PROTEIN 1 cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;membrane#GO:0016020 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000004168.3|UniProtKB=G3QNH7 G3QNH7 PIGT PTHR12959:SF11 GPI TRANSAMIDASE COMPONENT PIG-T-RELATED GPI-ANCHOR TRANSAMIDASE COMPONENT PIGT macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;peptidase complex#GO:1905368;cytoplasm#GO:0005737;caspase complex#GO:0008303;endoplasmic reticulum membrane#GO:0005789;endopeptidase complex#GO:1905369;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000039598.1|UniProtKB=A0A2I2Z010 A0A2I2Z010 TMEM129 PTHR31322:SF2 E3 UBIQUITIN-PROTEIN LIGASE TM129 E3 UBIQUITIN-PROTEIN LIGASE TM129 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012719.3|UniProtKB=G3RAD4 G3RAD4 CHN2 PTHR46075:SF4 CHIMERIN FAMILY MEMBER BETA-CHIMAERIN enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 organelle assembly#GO:0070925;spermatid differentiation#GO:0048515;cellular component assembly involved in morphogenesis#GO:0010927;sexual reproduction#GO:0019953;spermatid development#GO:0007286;acrosome assembly#GO:0001675;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;cellular component organization#GO:0016043;developmental process involved in reproduction#GO:0003006;anatomical structure morphogenesis#GO:0009653;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;anatomical structure formation involved in morphogenesis#GO:0048646;vesicle organization#GO:0016050;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;male gamete generation#GO:0048232;endomembrane system organization#GO:0010256 GORGO|Ensembl=ENSGGOG00000008041.3|UniProtKB=G3S6N5 G3S6N5 VPS11 PTHR23323:SF24 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;vesicle organization#GO:0016050;endosome organization#GO:0007032;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284;endomembrane system organization#GO:0010256 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle tethering complex#GO:0099023;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000012511.3|UniProtKB=G3R9W9 G3R9W9 ZNF638 PTHR15592:SF1 MATRIN 3/NUCLEAR PROTEIN 220-RELATED ZINC FINGER PROTEIN 638 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000041125.1|UniProtKB=A0A2I2ZRT8 A0A2I2ZRT8 PTHR43195:SF3 TRANSKETOLASE TRANSKETOLASE heterocyclic compound binding#GO:1901363;transketolase or transaldolase activity#GO:0016744;transferase activity#GO:0016740;catalytic activity#GO:0003824;cation binding#GO:0043169;transketolase activity#GO:0004802;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;NADPH regeneration#GO:0006740;nucleotide metabolic process#GO:0009117;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;transketolase#PC00221 Pentose phosphate pathway#P02762>Transketolase#P03082 GORGO|Ensembl=ENSGGOG00000014429.3|UniProtKB=G3RXI5 G3RXI5 TSPAN16 PTHR19282:SF455 TETRASPANIN TETRASPANIN-16 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007632.3|UniProtKB=G3QXC3 G3QXC3 PTGER4 PTHR11866:SF6 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;cell communication#GO:0007154;cellular response to alcohol#GO:0097306;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;negative regulation of response to external stimulus#GO:0032102;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;regulation of biological quality#GO:0065008;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to alcohol#GO:0097305;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 GORGO|Ensembl=ENSGGOG00000038262.1|UniProtKB=G3RIS5 G3RIS5 PTHR23232:SF86 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011835.3|UniProtKB=G3R841 G3R841 UBALD2 PTHR31993:SF6 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000004926.3|UniProtKB=G3QQG0 G3QQG0 LRRC26 PTHR46473:SF2 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 26 molecular function activator activity#GO:0140677;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;potassium channel regulator activity#GO:0015459;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel regulator activity#GO:0016247;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter binding#GO:0044325;potassium channel activity#GO:0005267;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 GORGO|Ensembl=ENSGGOG00000042744.1|UniProtKB=A0A2I2ZK78 A0A2I2ZK78 LOC101137860 PTHR43986:SF5 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000036517.1|UniProtKB=A0A2I2YTC6 A0A2I2YTC6 PTHR46126:SF3 DYNACTIN SUBUNIT 5 DCTN5 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000000891.3|UniProtKB=A0A2I2Z838 A0A2I2Z838 TNIP1 PTHR31882:SF3 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 1 binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;mitogen-activated protein kinase binding#GO:0051019 negative regulation of signal transduction#GO:0009968;negative regulation of ERK1 and ERK2 cascade#GO:0070373;response to chemical#GO:0042221;regulation of ERK1 and ERK2 cascade#GO:0070372;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to lipopolysaccharide#GO:0032496;regulation of MAPK cascade#GO:0043408;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;cellular response to molecule of bacterial origin#GO:0071219;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;cellular response to biotic stimulus#GO:0071216;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;response to bacterium#GO:0009617 GORGO|Ensembl=ENSGGOG00000013470.3|UniProtKB=G3RCB7 G3RCB7 WIZ PTHR24396:SF22 ZINC FINGER PROTEIN PROTEIN WIZ cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013797.3|UniProtKB=G3RD64 G3RD64 ROR1 PTHR24416:SF134 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR1 kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;Wnt-protein binding#GO:0017147;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;signaling receptor complex#GO:0043235;axon#GO:0030424 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012122.3|UniProtKB=G3R8V2 G3R8V2 PTHR24245:SF4 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 45-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 GORGO|Ensembl=ENSGGOG00000001192.3|UniProtKB=A1YF12 A1YF12 ZNF16 PTHR24393:SF186 ZINC FINGER PROTEIN ENDOTHELIAL ZINC FINGER PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000021951.2|UniProtKB=G3SCN4 G3SCN4 PTHR11346:SF194 GALECTIN GALECTIN-9C carbohydrate binding#GO:0030246;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cell activation#GO:0050866;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cytokine production#GO:0001817;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;negative regulation of T cell activation#GO:0050868;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of T cell proliferation#GO:0042129;regulation of macromolecule metabolic process#GO:0060255;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of multicellular organismal process#GO:0051241;negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663;regulation of multicellular organismal process#GO:0051239;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of metabolic process#GO:0009892;regulation of lymphocyte activation#GO:0051249;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000016373.3|UniProtKB=G3RJS5 G3RJS5 TAGLN3 PTHR47385:SF10 CALPONIN TRANSGELIN-3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000015255.3|UniProtKB=G3RGX4 G3RGX4 ERCC3 PTHR11274:SF18 RAD25/XP-B DNA REPAIR HELICASE GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE_TRANSLOCASE SUBUNIT XPB ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;hair cell differentiation#GO:0035315;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;gene expression#GO:0010467;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;nucleic acid biosynthetic process#GO:0141187;generation of neurons#GO:0048699;RNA metabolic process#GO:0016070;DNA-templated transcription initiation#GO:0006352;cell differentiation#GO:0030154;epidermis development#GO:0008544;transcription by RNA polymerase II#GO:0006366;developmental process#GO:0032502;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;neurogenesis#GO:0022008;macromolecule biosynthetic process#GO:0009059;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;anatomical structure development#GO:0048856;system development#GO:0048731;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nucleotide-excision repair complex#GO:0000109;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II, holoenzyme#GO:0016591 DNA metabolism protein#PC00009;DNA helicase#PC00011 GORGO|Ensembl=ENSGGOG00000015677.3|UniProtKB=A0A2I2Z6K5 A0A2I2Z6K5 PTHR45623:SF19 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD2 ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ATP hydrolysis activity#GO:0016887;DNA binding#GO:0003677;hydrolase activity#GO:0016787;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000028109.2|UniProtKB=G3S0J9 G3S0J9 LYPD8 PTHR20914:SF2 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 LY6_PLAUR DOMAIN-CONTAINING PROTEIN 8 defense response#GO:0006952;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014997.3|UniProtKB=G3RG95 G3RG95 DLX3 PTHR24327:SF28 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;embryo development ending in birth or egg hatching#GO:0009792;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;skeletal system development#GO:0001501;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000008265.3|UniProtKB=A0A2I2Z437 A0A2I2Z437 ATP5PF PTHR12441:SF10 ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT F6, MITOCHONDRIAL membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;proton-transporting ATP synthase complex#GO:0045259;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 primary active transporter#PC00068;ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000015804.3|UniProtKB=G3RIB6 G3RIB6 TSEN15 PTHR28582:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15 GORGO|Ensembl=ENSGGOG00000026750.2|UniProtKB=G3SAM6 G3SAM6 LOC101150074 PTHR12100:SF2 SEC10 EXOCYST COMPLEX COMPONENT 5 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;secretion by cell#GO:0032940;exocytosis#GO:0006887;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;cytoplasm#GO:0005737;exocyst#GO:0000145;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cell cortex#GO:0005938 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000025692.3|UniProtKB=G3RRB2 G3RRB2 SCAPER PTHR31434:SF2 S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM GORGO|Ensembl=ENSGGOG00000014680.3|UniProtKB=G3RFF7 G3RFF7 ST6GALNAC4 PTHR23136:SF8 TAX1-BINDING PROTEIN 3-RELATED ALPHA-N-ACETYLNEURAMINYL-2,3-BETA-GALACTOSYL-1,3-N-ACETYLGALACTOSAMINIDE6-ALPHA-SIALYLTRANSFERASE GORGO|Ensembl=ENSGGOG00000038104.1|UniProtKB=A0A2I2ZJX3 A0A2I2ZJX3 SAAL1 PTHR23424:SF35 SERUM AMYLOID A PROTEIN SAAL1 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;positive regulation of epithelial cell proliferation#GO:0050679;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127 organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000005101.3|UniProtKB=G3QQX0 G3QQX0 TMED9 PTHR22811:SF37 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 9 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193 coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000038748.1|UniProtKB=G3QXG0 G3QXG0 LOC101130985 PTHR23428:SF374 HISTONE H2B HISTONE H2B TYPE 1-B response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000014110.3|UniProtKB=A0A2I2YUY0 A0A2I2YUY0 PTHR45624:SF7 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 48 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023935.2|UniProtKB=A0A2I2Y9Q4 A0A2I2Y9Q4 PTHR31259:SF5 ENDOSOME-ASSOCIATED TRAFFICKING REGULATOR 1 ENDOSOME-ASSOCIATED-TRAFFICKING REGULATOR 1 regulation of cell projection organization#GO:0031344;regulation of cilium assembly#GO:1902017;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of localization#GO:0032879;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;positive regulation of organelle organization#GO:0010638;regulation of protein localization#GO:0032880;regulation of cell projection assembly#GO:0060491;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087 membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;recycling endosome#GO:0055037;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;midbody#GO:0030496;intracellular vesicle#GO:0097708;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000014485.3|UniProtKB=G3REY2 G3REY2 SESN2 PTHR12474:SF2 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-2 catalytic activity#GO:0003824;amino acid binding#GO:0016597;oxidoreductase activity#GO:0016491;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;organic acid binding#GO:0043177;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;cation binding#GO:0043169 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;response to nitrogen compound#GO:1901698;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;regulation of macroautophagy#GO:0016241;negative regulation of TORC1 signaling#GO:1904262;positive regulation of macroautophagy#GO:0016239;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007315.3|UniProtKB=G3QWK0 G3QWK0 LIPM PTHR11005:SF12 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER M lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 lipase#PC00143;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000012650.3|UniProtKB=G3RUR1 G3RUR1 CCDC40 PTHR16275:SF9 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 cellular component assembly#GO:0022607;heart development#GO:0007507;determination of bilateral symmetry#GO:0009855;embryo development#GO:0009790;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;microtubule-based process#GO:0007017;left/right pattern formation#GO:0060972;circulatory system development#GO:0072359;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;anatomical structure morphogenesis#GO:0009653;cilium organization#GO:0044782;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;cilium movement#GO:0003341;regionalization#GO:0003002;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelium development#GO:0060429;plasma membrane bounded cell projection organization#GO:0120036;tube development#GO:0035295;establishment of localization#GO:0051234;plasma membrane bounded cell projection assembly#GO:0120031;specification of symmetry#GO:0009799;transport#GO:0006810;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;microtubule-based movement#GO:0007018;tube morphogenesis#GO:0035239;heart morphogenesis#GO:0003007;determination of left/right symmetry#GO:0007368;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;localization#GO:0051179;system development#GO:0048731;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;embryonic organ development#GO:0048568;pattern specification process#GO:0007389 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000007416.3|UniProtKB=G3QWT7 G3QWT7 PTHR16260:SF4 SIMILAR TO 1700123O20RIK PROTEIN SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000009634.2|UniProtKB=G3R2F4 G3R2F4 CCDC87 PTHR16078:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 87 COILED-COIL DOMAIN-CONTAINING PROTEIN 87 GORGO|Ensembl=ENSGGOG00000015854.3|UniProtKB=G3RMR3 G3RMR3 EIF4E1B PTHR11960:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000007991.3|UniProtKB=G3QY86 G3QY86 ODC1 PTHR11482:SF42 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829 polyamine biosynthetic process#GO:0006596;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;polyamine metabolic process#GO:0006595 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 CCKR signaling map#P06959>ODC1#G06989;CCKR signaling map#P06959>ODC1#P07221;Ornithine degradation#P02758>Ornithine decarboxylase#P03053 GORGO|Ensembl=ENSGGOG00000016196.3|UniProtKB=G3S9N1 G3S9N1 SDR39U1 PTHR11092:SF0 SUGAR NUCLEOTIDE EPIMERASE RELATED EPIMERASE FAMILY PROTEIN SDR39U1 epimerase/racemase#PC00096 GORGO|Ensembl=ENSGGOG00000001372.3|UniProtKB=G3QGA3 G3QGA3 PCDH10 PTHR24028:SF0 CADHERIN-87A PROTOCADHERIN-10 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000038850.1|UniProtKB=G3RAZ5 G3RAZ5 NPPA PTHR14066:SF2 ATRIAL NATRIURETIC FACTOR PRECURSOR NATRIURETIC PEPTIDES A signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;hormone receptor binding#GO:0051427 cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribose phosphate biosynthetic process#GO:0046390;regulation of systemic arterial blood pressure#GO:0003073;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;regulation of biological quality#GO:0065008;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic nucleotide metabolic process#GO:0009187;system process#GO:0003008;nucleoside phosphate biosynthetic process#GO:1901293;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;regulation of blood pressure#GO:0008217;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;circulatory system process#GO:0003013;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;neuropeptide signaling pathway#GO:0007218;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000007702.3|UniProtKB=G3QXJ1 G3QXJ1 EHHADH PTHR23309:SF9 3-HYDROXYACYL-COA DEHYROGENASE PEROXISOMAL BIFUNCTIONAL ENZYME oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005478.3|UniProtKB=G3SCM6 G3SCM6 ZMYND15 PTHR47085:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;histone deacetylase binding#GO:0042826 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;spermatid development#GO:0007286;sexual reproduction#GO:0019953;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;spermatid differentiation#GO:0048515;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 GORGO|Ensembl=ENSGGOG00000002105.3|UniProtKB=G3QI70 G3QI70 TRAPPC9 PTHR21512:SF5 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;intracellular vesicle#GO:0097708;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000003526.3|UniProtKB=G3QLV1 G3QLV1 DBF4B PTHR15375:SF24 ACTIVATOR OF S-PHASE KINASE-RELATED PROTEIN DBF4 HOMOLOG B protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 regulation of cell cycle#GO:0051726;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of cell cycle phase transition#GO:1901987;positive regulation of DNA metabolic process#GO:0051054;positive regulation of metabolic process#GO:0009893;regulation of DNA replication#GO:0006275;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA replication#GO:0045740;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 kinase activator#PC00138;kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000043332.1|UniProtKB=A0A2I2Z642 A0A2I2Z642 LOC101152403 PTHR12146:SF8 40S RIBOSOMAL PROTEIN S10 RIBOSOMAL PROTEIN ES10-LIKE-RELATED RNA binding#GO:0003723;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000024100.2|UniProtKB=A0A2I2YV65 A0A2I2YV65 PTHR21230:SF65 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein binding#GO:0005515;SNAP receptor activity#GO:0005484 vesicle fusion#GO:0006906;catabolic process#GO:0009056;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;membrane organization#GO:0061024;macroautophagy#GO:0016236;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;post-Golgi vesicle-mediated transport#GO:0006892;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;endosomal transport#GO:0016197;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133 SNARE protein#PC00034;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000002305.3|UniProtKB=G3QIQ3 G3QIQ3 PTHR10913:SF13 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 1 cellular process#GO:0009987;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 GORGO|Ensembl=ENSGGOG00000041016.1|UniProtKB=A0A2I2Z3E9 A0A2I2Z3E9 BCL2L15 PTHR36466:SF1 BCL-2-LIKE PROTEIN 15 BCL-2-LIKE PROTEIN 15 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000013337.3|UniProtKB=G3RBZ4 G3RBZ4 SLC2A10 PTHR48023:SF7 D-XYLOSE-PROTON SYMPORTER-LIKE 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 10 sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 multicellular organism development#GO:0007275;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;carbohydrate transport#GO:0008643;developmental process#GO:0032502;transport#GO:0006810;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025251.2|UniProtKB=G3SGZ6 G3SGZ6 PTHR14679:SF1 GEM-ASSOCIATED PROTEIN 7 GEM-ASSOCIATED PROTEIN 7 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607 protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114 GORGO|Ensembl=ENSGGOG00000012484.3|UniProtKB=G3SA85 G3SA85 CWC22 PTHR18034:SF3 CELL CYCLE CONTROL PROTEIN CWF22-RELATED PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000000152.3|UniProtKB=G3QD46 G3QD46 PTHR44324:SF6 WD40 REPEAT DOMAIN 95 WD REPEAT-CONTAINING PROTEIN ON Y CHROMOSOME GORGO|Ensembl=ENSGGOG00000005258.3|UniProtKB=G3QRC7 G3QRC7 PTHR32170:SF5 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 nucleus#GO:0005634;proteasome complex#GO:0000502;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007928.3|UniProtKB=G3QY28 G3QY28 GSX2 PTHR47421:SF1 GS HOMEOBOX 2 GS HOMEOBOX 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007088.3|UniProtKB=G3QW00 G3QW00 MSH2 PTHR11361:SF156 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH2 molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune system development#GO:0002520;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;cellular response to stress#GO:0033554;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896;mismatch repair#GO:0006298;multicellular organism development#GO:0007275;immune effector process#GO:0002252;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;gene expression#GO:0010467;cellular process#GO:0009987;somatic recombination of immunoglobulin gene segments#GO:0016447;response to stress#GO:0006950;system development#GO:0048731;anatomical structure development#GO:0048856;mitotic recombination#GO:0006312;cellular response to stimulus#GO:0051716;somatic diversification of immune receptors#GO:0002200;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;developmental process#GO:0032502;DNA repair#GO:0006281;adaptive immune response#GO:0002250;somatic cell DNA recombination#GO:0016444;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000026761.2|UniProtKB=A0A2I2YEU7 A0A2I2YEU7 PTHR15197:SF0 COILIN P80 COILIN RNA binding#GO:0003723;snRNA binding#GO:0017069;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000009361.3|UniProtKB=G3R1R3 G3R1R3 HS3ST6 PTHR10605:SF62 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 6 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000022531.2|UniProtKB=G3RUZ0 G3RUZ0 ST3GAL1 PTHR46032:SF6 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 1 sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000002349.3|UniProtKB=G3QIU4 G3QIU4 GIMAP7 PTHR10903:SF199 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000006700.3|UniProtKB=G3QV04 G3QV04 PWP1 PTHR14091:SF0 PERIODIC TRYPTOPHAN PROTEIN 1 PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase I#GO:0045943;regulation of transcription by RNA polymerase I#GO:0006356;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008141.3|UniProtKB=G3QYL6 G3QYL6 NKD1 PTHR22611:SF2 PROTEIN NAKED CUTICLE PROTEIN NAKED CUTICLE HOMOLOG 1 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Wnt signaling pathway#P00057>Naked#P01427 GORGO|Ensembl=ENSGGOG00000042510.1|UniProtKB=G3QIY5 G3QIY5 LOC101140970 PTHR48018:SF72 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000705.3|UniProtKB=G3QEJ7 G3QEJ7 LOC101141704 PTHR10106:SF12 CYTOCHROME B561-RELATED PLASMA MEMBRANE ASCORBATE-DEPENDENT REDUCTASE CYBRD1 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824 intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;carbohydrate homeostasis#GO:0033500;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;brush border membrane#GO:0031526;plasma membrane region#GO:0098590;brush border#GO:0005903;cell periphery#GO:0071944;membrane#GO:0016020;apical plasma membrane#GO:0016324;cluster of actin-based cell projections#GO:0098862;cell projection membrane#GO:0031253;apical part of cell#GO:0045177 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000003414.3|UniProtKB=G3QLK0 G3QLK0 PSPC1 PTHR23189:SF14 RNA RECOGNITION MOTIF-CONTAINING PARASPECKLE COMPONENT 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013838.3|UniProtKB=G3RDA0 G3RDA0 ZNF124 PTHR24379:SF136 KRAB AND ZINC FINGER DOMAIN-CONTAINING TRANSCRIPTION FACTOR E4F1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007139.3|UniProtKB=G3QW34 G3QW34 TMEM247 PTHR36691:SF1 TRANSMEMBRANE PROTEIN 247 TRANSMEMBRANE PROTEIN 247 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000011787.3|UniProtKB=G3R805 G3R805 GTF3C3 PTHR23082:SF0 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3 DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;transcription factor TFIIIC complex#GO:0000127 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008388.3|UniProtKB=G3QZ98 G3QZ98 KCNQ2 PTHR11537:SF6 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 2 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244 action potential#GO:0001508;metal ion transport#GO:0030001;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 voltage-gated ion channel#PC00241;ion channel#PC00133 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>K+ channel#P01070 GORGO|Ensembl=ENSGGOG00000036701.1|UniProtKB=A0A2I2YBC5 A0A2I2YBC5 PTHR23411:SF39 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1-RELATED antigen binding#GO:0003823;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 immune response#GO:0006955;complement activation#GO:0006956;biological regulation#GO:0065007;adaptive immune response#GO:0002250;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;defense response#GO:0006952;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;defense response to other organism#GO:0098542;immune effector process#GO:0002252;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;antibacterial humoral response#GO:0019731;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000026335.2|UniProtKB=G3S784 G3S784 MYT1L PTHR10816:SF11 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000008726.3|UniProtKB=G3RS81 G3RS81 SWAP70 PTHR14383:SF6 SWAP-70 RECOMBINASE SWITCH-ASSOCIATED PROTEIN 70 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015260.3|UniProtKB=G3RGX9 G3RGX9 ZNF346 PTHR46144:SF5 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER PROTEIN 346 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723 GORGO|Ensembl=ENSGGOG00000004795.3|UniProtKB=A0A2I2YR90 A0A2I2YR90 SEMA4B PTHR11036:SF14 SEMAPHORIN SEMAPHORIN-4B receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;taxis#GO:0042330;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;axon guidance#GO:0007411;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000043148.1|UniProtKB=A0A2I2YGS1 A0A2I2YGS1 TAL1 PTHR13864:SF16 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000022038.2|UniProtKB=G3RUA8 G3RUA8 HTR2B PTHR24247:SF31 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2B signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165 dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414 GORGO|Ensembl=ENSGGOG00000037040.1|UniProtKB=A0A2I2ZR67 A0A2I2ZR67 ALKBH6 PTHR46030:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6 RNA_DNA DEMETHYLASE ALKBH6-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000010027.3|UniProtKB=G3RMJ3 G3RMJ3 RARS2 PTHR11956:SF11 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000012308.3|UniProtKB=G3R9C8 G3R9C8 LOC101150438 PTHR43448:SF2 PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;porphyrin-containing compound biosynthetic process#GO:0006779;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042;transferase#PC00220 Heme biosynthesis#P02746>Protoheme IX farnesyl transferase#P02982 GORGO|Ensembl=ENSGGOG00000016397.3|UniProtKB=G3S318 G3S318 ANKRD13C PTHR12447:SF39 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100;regulation of cellular process#GO:0050794;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cell periphery#GO:0071944;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013711.3|UniProtKB=A0A2I2YGD1 A0A2I2YGD1 EXOC3 PTHR21292:SF13 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810 cytoplasm#GO:0005737;exocyst#GO:0000145;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006289.3|UniProtKB=G3QTW1 G3QTW1 HOXC8 PTHR46166:SF4 HOMEOBOX DOMAIN-CONTAINING PROTEIN HOMEOBOX PROTEIN HOX-C8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000040673.1|UniProtKB=A0A2I2ZHR8 A0A2I2ZHR8 TMEM225B PTHR36477:SF2 TRANSMEMBRANE PROTEIN 225 TRANSMEMBRANE PROTEIN 225B GORGO|Ensembl=ENSGGOG00000028064.2|UniProtKB=G3SG76 G3SG76 CFAP157 PTHR31954:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000000671.3|UniProtKB=G3QEG6 G3QEG6 ADCY9 PTHR45627:SF8 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 9 lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cyclic nucleotide biosynthetic process#GO:0009190;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 GABA-B receptor II signaling#P05731>AC#P05760;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 GORGO|Ensembl=ENSGGOG00000022032.2|UniProtKB=G3S8Y2 G3S8Y2 ZNF771 PTHR24376:SF201 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 771 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000008551.3|UniProtKB=G3QZP2 G3QZP2 PTHR26452:SF135 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H15 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000040528.1|UniProtKB=A0A2I2ZST4 A0A2I2ZST4 LOC109025964 PTHR19269:SF76 TROPOMYOSIN TPM3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 actin filament-based process#GO:0030029;muscle contraction#GO:0006936;system process#GO:0003008;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;muscle system process#GO:0003012;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000013986.3|UniProtKB=G3RSL3 G3RSL3 PTHR15566:SF7 POM121-LIKE UPF0607 PROTEIN ENSP00000381514-RELATED GORGO|Ensembl=ENSGGOG00000005060.3|UniProtKB=G3QQT5 G3QQT5 LRRC72 PTHR46759:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 GORGO|Ensembl=ENSGGOG00000038292.1|UniProtKB=G3RYI3 G3RYI3 PTHR23262:SF212 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-8 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000015031.3|UniProtKB=G3RGC9 G3RGC9 LOC101149484 PTHR19359:SF158 CYTOCHROME B5 CYTOCHROME B5 TYPE B binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000039626.1|UniProtKB=G3S9E7 G3S9E7 PTHR12801:SF22 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED EXONUCLEASE GOR-RELATED hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000004935.3|UniProtKB=G3QQG9 G3QQG9 ROPN1L PTHR14952:SF14 ROPPORIN-1-LIKE PROTEIN ROPPORIN-1-LIKE PROTEIN cilium-dependent cell motility#GO:0060285;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sexual reproduction#GO:0019953;spermatid development#GO:0007286;cell differentiation#GO:0030154;gamete generation#GO:0007276;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;sperm motility#GO:0097722;cell maturation#GO:0048469;cellular developmental process#GO:0048869;microtubule-based process#GO:0007017;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;developmental maturation#GO:0021700;male gamete generation#GO:0048232;sperm capacitation#GO:0048240;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987 cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000043743.1|UniProtKB=A0A2I2ZGR9 A0A2I2ZGR9 PTHR46485:SF1 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000027159.2|UniProtKB=A0A2I2Y2L3 A0A2I2Y2L3 CIMAP1D PTHR21580:SF62 SHIPPO-1-RELATED PROTEIN CIMAP1D cellular process#GO:0009987;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;spermatid development#GO:0007286;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;microtubule cytoskeleton#GO:0015630 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000022830.2|UniProtKB=G3RZQ1 G3RZQ1 LOC101149184 PTHR31283:SF13 EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER CANCER_TESTIS ANTIGEN 1A protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000014840.3|UniProtKB=G3RFV1 G3RFV1 IZUMO1R PTHR10517:SF10 FOLATE RECEPTOR SPERM-EGG FUSION PROTEIN JUNO molecular transducer activity#GO:0060089;cargo receptor activity#GO:0038024;signaling receptor activity#GO:0038023 fertilization#GO:0009566;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;vitamin transport#GO:0051180;multicellular organismal reproductive process#GO:0048609;localization#GO:0051179;cell recognition#GO:0008037;sexual reproduction#GO:0019953;dicarboxylic acid transport#GO:0006835;cellular process#GO:0009987;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;single fertilization#GO:0007338;nitrogen compound transport#GO:0071705;cell-cell recognition#GO:0009988;establishment of localization#GO:0051234;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;sperm-egg recognition#GO:0035036 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000010496.3|UniProtKB=G3RZK2 G3RZK2 KCTD5 PTHR14958:SF12 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD5 protein binding#GO:0005515;binding#GO:0005488 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004062.3|UniProtKB=G3QN77 G3QN77 PSMD4 PTHR10223:SF7 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 nucleus#GO:0005634;proteasome complex#GO:0000502;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 GORGO|Ensembl=ENSGGOG00000027517.2|UniProtKB=A0A2I2Y1R4 A0A2I2Y1R4 EIF3K PTHR13022:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000036796.1|UniProtKB=A0A2I2Z561 A0A2I2Z561 ATP5MC3 PTHR10031:SF54 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C2, MITOCHONDRIAL primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000000135.4|UniProtKB=G3QD31 G3QD31 SGCZ PTHR12939:SF5 SARCOGLYCAN ZETA-SARCOGLYCAN system development#GO:0048731;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;circulatory system process#GO:0003013;circulatory system development#GO:0072359;heart process#GO:0003015;system process#GO:0003008;heart contraction#GO:0060047;animal organ development#GO:0048513;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;heart development#GO:0007507;blood circulation#GO:0008015 sarcolemma#GO:0042383;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000009417.3|UniProtKB=G3RZU7 G3RZU7 TSEN54 PTHR21027:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000022030.2|UniProtKB=G3QNG6 G3QNG6 CMTM1 PTHR22776:SF43 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 immune response#GO:0006955;regulation of biological process#GO:0050789;immune system process#GO:0002376;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004733.3|UniProtKB=G3QPX8 G3QPX8 CD207 PTHR22802:SF14 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER K carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000003636.3|UniProtKB=A0A2I2YUC0 A0A2I2YUC0 LDLR PTHR24270:SF21 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR low-density lipoprotein particle receptor activity#GO:0005041;cargo receptor activity#GO:0038024 cholesterol homeostasis#GO:0042632;import into cell#GO:0098657;establishment of localization#GO:0051234;sterol transport#GO:0015918;receptor-mediated endocytosis#GO:0006898;intracellular transport#GO:0046907;transport#GO:0006810;chemical homeostasis#GO:0048878;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;endocytosis#GO:0006897;intracellular sterol transport#GO:0032366;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000013641.3|UniProtKB=G3SEG6 G3SEG6 KIAA2013 PTHR31386:SF2 UNCHARACTERIZED PROTEIN KIAA2013 RIKEN CDNA 2510039O18 GENE LIKE GORGO|Ensembl=ENSGGOG00000038559.1|UniProtKB=A0A2I2Y4K1 A0A2I2Y4K1 PTHR45722:SF37 60S RIBOSOMAL PROTEIN L35 LARGE RIBOSOMAL SUBUNIT PROTEIN UL29 RNA binding#GO:0003723;structural molecule activity#GO:0005198;mRNA binding#GO:0003729;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010633.3|UniProtKB=G3R4Z9 G3R4Z9 LOC101123691 PTHR26453:SF112 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B11 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007825.3|UniProtKB=A0A2I2Z6E5 A0A2I2Z6E5 SCUBE2 PTHR24046:SF3 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 2 muscle cell development#GO:0055001;response to endogenous stimulus#GO:0009719;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;response to BMP#GO:0071772;cellular developmental process#GO:0048869 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000003760.3|UniProtKB=G3QMF9 G3QMF9 DICER1 PTHR14950:SF82 DICER-RELATED ENDORIBONUCLEASE DICER catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;binding#GO:0005488;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cell death#GO:0008219;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;DNA catabolic process#GO:0006308;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;siRNA processing#GO:0030422;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;apoptotic DNA fragmentation#GO:0006309 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000015186.3|UniProtKB=G3RGR0 G3RGR0 TMEM82 PTHR35257:SF1 TRANSMEMBRANE PROTEIN 82 TRANSMEMBRANE PROTEIN 82 GORGO|Ensembl=ENSGGOG00000009804.3|UniProtKB=G3SCA9 G3SCA9 HNRNPUL1 PTHR12381:SF41 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000041414.1|UniProtKB=A0A2I2YSQ6 A0A2I2YSQ6 PTHR11205:SF38 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 RNA binding#GO:0003723;structural molecule activity#GO:0005198;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000003960.3|UniProtKB=G3QMY5 G3QMY5 PTHR43084:SF1 PERSULFIDE DIOXYGENASE ETHE1 PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010608.3|UniProtKB=A0A2I2ZGC5 A0A2I2ZGC5 HDAC5 PTHR10625:SF28 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 5 histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000005342.3|UniProtKB=A0A2I2YP72 A0A2I2YP72 SCNN1D PTHR11690:SF132 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED EPITHELIAL SODIUM CHANNEL SUBUNIT DELTA passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 cation channel complex#GO:0034703;sodium channel complex#GO:0034706;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000015718.3|UniProtKB=G3RI46 G3RI46 OR10H1 PTHR26453:SF712 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10H1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003539.3|UniProtKB=G3QLW2 G3QLW2 USP20 PTHR24006:SF823 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000008116.3|UniProtKB=A0A2I2ZJ29 A0A2I2ZJ29 SNX14 PTHR22775:SF44 SORTING NEXIN SORTING NEXIN-14 anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167 protein-containing complex organization#GO:0043933;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;macroautophagy#GO:0016236;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006604.3|UniProtKB=G3QUQ6 G3QUQ6 C21H20orf96 PTHR28574:SF1 RIKEN CDNA 6820408C15 RIKEN CDNA 6820408C15 GENE GORGO|Ensembl=ENSGGOG00000036829.1|UniProtKB=A0A2I2YBV8 A0A2I2YBV8 PTHR11673:SF35 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER TRANSLATION INITIATION FACTOR 5A C-TERMINAL DOMAIN-CONTAINING PROTEIN translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000043551.1|UniProtKB=A0A2I2ZVQ9 A0A2I2ZVQ9 PTHR10063:SF0 TUBERIN TUBERIN enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell cycle#GO:0051726;positive regulation of macroautophagy#GO:0016239;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of macroautophagy#GO:0016241;negative regulation of TORC1 signaling#GO:1904262;intracellular signaling cassette#GO:0141124;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of autophagy#GO:0010508 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;GTPase-activating protein#PC00257 p53 pathway by glucose deprivation#P04397>TSC2#P04644;p53 pathway by glucose deprivation#P04397>TSC2#G04706;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC2#P04494 GORGO|Ensembl=ENSGGOG00000014759.3|UniProtKB=G3RFM9 G3RFM9 FAM219B PTHR31281:SF2 PROTEIN FAM219A PROTEIN FAM219B GORGO|Ensembl=ENSGGOG00000038585.1|UniProtKB=A0A2I2YMU7 A0A2I2YMU7 PTHR45809:SF5 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 3 growth factor receptor binding#GO:0070851;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;angiogenesis#GO:0001525;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;protein folding#GO:0006457;circulatory system development#GO:0072359;metabolic process#GO:0008152;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;protein maturation#GO:0051604;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;biosynthetic process#GO:0009058;tube development#GO:0035295;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000010951.3|UniProtKB=G3R5T7 G3R5T7 ASB16 PTHR24173:SF44 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 13 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000779.3|UniProtKB=G3QER9 G3QER9 PTHR24257:SF16 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER NEUTROPHIL ELASTASE serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 inflammatory response#GO:0006954;immune system process#GO:0002376;proteolysis#GO:0006508;acute inflammatory response#GO:0002526;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;cell motility#GO:0048870;endocytosis#GO:0006897;response to stimulus#GO:0050896;transport#GO:0006810;phagocytosis#GO:0006909;metabolic process#GO:0008152;leukocyte migration#GO:0050900;defense response#GO:0006952;establishment of localization#GO:0051234;import into cell#GO:0098657;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;immune response#GO:0006955;response to stress#GO:0006950;cell migration#GO:0016477 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023299.2|UniProtKB=G3RRI4 G3RRI4 COA7 PTHR13891:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000023264.2|UniProtKB=G3SFZ1 G3SFZ1 POLRMT PTHR10102:SF28 DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;mitochondrial transcription#GO:0006390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;RNA polymerase complex#GO:0030880;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000006427.3|UniProtKB=G3SBL8 G3SBL8 FIP1L1 PTHR13484:SF9 FIP1-LIKE 1 PROTEIN PRE-MRNA 3'-END-PROCESSING FACTOR FIP1 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 GORGO|Ensembl=ENSGGOG00000003124.3|UniProtKB=G3QKU1 G3QKU1 ACCS PTHR43795:SF17 BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE-LIKE PROTEIN 1 catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846 transferase#PC00220;transaminase#PC00216;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002460.3|UniProtKB=A0A2I2Z5V2 A0A2I2Z5V2 SEC22A PTHR46258:SF3 LONGIN DOMAIN-CONTAINING PROTEIN VESICLE-TRAFFICKING PROTEIN SEC22A establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 GORGO|Ensembl=ENSGGOG00000022418.2|UniProtKB=G3S291 G3S291 FAM32A PTHR13282:SF10 PROTEIN FAM32A PROTEIN FAM32A membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000010039.3|UniProtKB=G3R3J2 G3R3J2 FLNB PTHR38537:SF7 JITTERBUG, ISOFORM N FILAMIN-B Integrin signalling pathway#P00034>Filamin#P00914 GORGO|Ensembl=ENSGGOG00000003955.3|UniProtKB=A0A2I2YX52 A0A2I2YX52 UBE3A PTHR45622:SF82 UBIQUITIN-PROTEIN LIGASE E3A-RELATED UBIQUITIN-PROTEIN LIGASE E3A catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;protein modification by small protein conjugation or removal#GO:0070647;regulation of protein catabolic process#GO:0042176;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 GORGO|Ensembl=ENSGGOG00000022870.2|UniProtKB=G3SAM3 G3SAM3 SRD5A3 PTHR14624:SF0 DFG10 PROTEIN POLYPRENAL REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;phosphorus metabolic process#GO:0006793;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;glycoprotein biosynthetic process#GO:0009101 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002151.3|UniProtKB=G3QIB3 G3QIB3 LDB1 PTHR10378:SF7 LIM DOMAIN-BINDING PROTEIN LIM DOMAIN-BINDING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 Gonadotropin-releasing hormone receptor pathway#P06664>CLIM2#P06736 GORGO|Ensembl=ENSGGOG00000003364.3|UniProtKB=G3QLF7 G3QLF7 DAGLB PTHR45792:SF2 DIACYLGLYCEROL LIPASE HOMOLOG-RELATED DIACYLGLYCEROL LIPASE-BETA hydrolase activity#GO:0016787;triacylglycerol lipase activity#GO:0004806;lipase activity#GO:0016298;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;arachidonate metabolic process#GO:0019369;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;olefinic compound metabolic process#GO:0120254;animal gross anatomical part developmental process#GO:0160108;glycerolipid catabolic process#GO:0046503;oxoacid metabolic process#GO:0043436;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid catabolic process#GO:0016042;icosanoid metabolic process#GO:0006690;nervous system development#GO:0007399;metabolic process#GO:0008152;unsaturated fatty acid metabolic process#GO:0033559;multicellular organism development#GO:0007275;acylglycerol catabolic process#GO:0046464;primary metabolic process#GO:0044238;catabolic process#GO:0009056;anatomical structure development#GO:0048856;system development#GO:0048731;multicellular organismal process#GO:0032501;fatty acid metabolic process#GO:0006631;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;developmental process#GO:0032502;cellular developmental process#GO:0048869;neutral lipid metabolic process#GO:0006638;neurogenesis#GO:0022008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 GORGO|Ensembl=ENSGGOG00000005137.3|UniProtKB=G3QR11 G3QR11 TNRC6A PTHR13020:SF28 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6A PROTEIN regulation of RNA metabolic process#GO:0051252;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of metabolic process#GO:0009893;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;miRNA-mediated post-transcriptional gene silencing#GO:0035195;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014078.3|UniProtKB=G3RDW5 G3RDW5 CXCR5 PTHR10489:SF618 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 5 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000006489.3|UniProtKB=G3QUE4 G3QUE4 C3H4orf3 PTHR37367:SF1 CHROMOSOME 4 OPEN READING FRAME 3 SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE REGULATOR ARLN GORGO|Ensembl=ENSGGOG00000034998.2|UniProtKB=G3SKP8 G3SKP8 EYA2 PTHR10190:SF7 EYES ABSENT PROTEIN PHOSPHATASE EYA2 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;positive regulation of DNA metabolic process#GO:0051054;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of response to stress#GO:0080134;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of macromolecule metabolic process#GO:0010604 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000001367.3|UniProtKB=G3S7F5 G3S7F5 RBM47 PTHR21245:SF6 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 47 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010375.3|UniProtKB=G3R4D5 G3R4D5 DENND5A PTHR46070:SF2 PINSTRIPE, ISOFORM A DENN DOMAIN-CONTAINING PROTEIN 5A nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267 cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000004478.3|UniProtKB=G3QPA3 G3QPA3 NKD2 PTHR22611:SF1 PROTEIN NAKED CUTICLE PROTEIN NAKED CUTICLE HOMOLOG 2 negative regulation of cell communication#GO:0010648;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of Wnt signaling pathway#GO:0030111;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Wnt signaling pathway#P00057>Naked#P01427 GORGO|Ensembl=ENSGGOG00000025423.2|UniProtKB=G3S8C5 G3S8C5 PCNP PTHR16523:SF8 PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000016631.3|UniProtKB=G3RKG4 G3RKG4 CEACAM20 PTHR44427:SF7 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM20 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;protein binding#GO:0005515 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000003089.3|UniProtKB=G3QKR4 G3QKR4 PTPN23 PTHR23030:SF45 PCD6 INTERACTING PROTEIN-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23 establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;macromolecule localization#GO:0033036;early endosome to late endosome transport#GO:0045022;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;protein metabolic process#GO:0019538;localization#GO:0051179;protein localization to vacuole#GO:0072665;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;endosomal transport#GO:0016197;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;protein transport#GO:0015031;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;endocytic recycling#GO:0032456;establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000001522.3|UniProtKB=G3QGP1 G3QGP1 SELENOH PTHR33638:SF1 SELENOPROTEIN H SELENOPROTEIN H membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000015379.3|UniProtKB=G3RH94 G3RH94 LOC101130739 PTHR11851:SF226 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365 membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endopeptidase complex#GO:1905369;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275;organelle lumen#GO:0043233;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000016218.3|UniProtKB=G3RJF0 G3RJF0 CROCC PTHR23159:SF17 CENTROSOMAL PROTEIN 2 ROOTLETIN microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000039.3|UniProtKB=G3QCU0 G3QCU0 SMUG1 PTHR13235:SF2 SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA N-glycosylase activity#GO:0019104 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;base-excision repair#GO:0006284;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA glycosylase#PC00010 GORGO|Ensembl=ENSGGOG00000003244.3|UniProtKB=G3QL46 G3QL46 DRD2 PTHR24248:SF87 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(2) DOPAMINE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960 modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;response to nitrogen compound#GO:1901698;adrenergic receptor signaling pathway#GO:0071875;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;negative regulation of cellular process#GO:0048523 plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>DRD2#P06758;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965;Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000012149.3|UniProtKB=G3R8Y5 G3R8Y5 FERMT3 PTHR16160:SF1 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 3 protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 blood coagulation#GO:0007596;platelet activation#GO:0030168;response to wounding#GO:0009611;homotypic cell-cell adhesion#GO:0034109;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;cell activation#GO:0001775;cell-substrate adhesion#GO:0031589;hemostasis#GO:0007599;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of cell adhesion mediated by integrin#GO:0033628;platelet aggregation#GO:0070527;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;leukocyte cell-cell adhesion#GO:0007159;coagulation#GO:0050817;cell-cell adhesion#GO:0098609;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;regulation of biological quality#GO:0065008;wound healing#GO:0042060;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-substrate junction#GO:0030055;anchoring junction#GO:0070161 GORGO|Ensembl=ENSGGOG00000040002.1|UniProtKB=A0A2I2ZGD5 A0A2I2ZGD5 STARD4 PTHR47006:SF1 STAR-RELATED LIPID TRANSFER PROTEIN 4 STAR-RELATED LIPID TRANSFER PROTEIN 4 binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;cholesterol binding#GO:0015485;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;sterol transfer activity#GO:0120015;transporter activity#GO:0005215;alcohol binding#GO:0043178;cholesterol transfer activity#GO:0120020;steroid binding#GO:0005496 establishment of localization in cell#GO:0051649;lipid storage#GO:0019915;cellular process#GO:0009987;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;intracellular transport#GO:0046907;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;sterol transport#GO:0015918;establishment of localization#GO:0051234;cellular localization#GO:0051641 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000025550.2|UniProtKB=G3S1V1 G3S1V1 PDCD4 PTHR12626:SF3 PROGRAMMED CELL DEATH 4 PROGRAMMED CELL DEATH PROTEIN 4 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000015177.3|UniProtKB=G3RGQ3 G3RGQ3 CCKAR PTHR24241:SF120 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CHOLECYSTOKININ RECEPTOR TYPE A transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 regulation of localization#GO:0032879;regulation of transport#GO:0051049;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010486.3|UniProtKB=A0A2I2Z2R2 A0A2I2Z2R2 MORN1 PTHR23084:SF263 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED MORN REPEAT-CONTAINING PROTEIN 1 transferase#PC00220;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000010894.3|UniProtKB=G3R5P0 G3R5P0 YIPF3 PTHR15627:SF14 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 PROTEIN YIPF3 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000015683.3|UniProtKB=G3SEB1 G3SEB1 UCHL3 PTHR10589:SF24 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L3 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007819.3|UniProtKB=A1YEY5 A1YEY5 GSC PTHR46643:SF2 HOMEOBOX PROTEIN GOOSECOID-RELATED HOMEOBOX PROTEIN GOOSECOID sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000004717.3|UniProtKB=G3QPW6 G3QPW6 GLIS2 PTHR19818:SF84 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN GLIS2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003329.3|UniProtKB=G3QLC8 G3QLC8 TCERG1 PTHR15377:SF7 TRANSCRIPTION ELONGATION REGULATOR 1 TRANSCRIPTION ELONGATION REGULATOR 1 binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;protein binding#GO:0005515 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000023884.2|UniProtKB=G3SAN2 G3SAN2 SYNGR4 PTHR10838:SF22 SYNAPTOGYRIN SYNAPTOGYRIN-4 transport#GO:0006810;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;secretion#GO:0046903;cellular process#GO:0009987;synaptic vesicle membrane organization#GO:0048499;cellular component organization#GO:0016043;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192 synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell junction#GO:0030054 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000036702.1|UniProtKB=A0A2I2ZAB1 A0A2I2ZAB1 PTHR22747:SF28 NUCLEOPLASMIN NUCLEOPHOSMIN protein binding#GO:0005515;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640;nuclear transport#GO:0051169;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;transport#GO:0006810;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;regulation of gene expression#GO:0010468;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular localization#GO:0051641;regulation of biological process#GO:0050789;ribosomal large subunit export from nucleus#GO:0000055;cellular component organization#GO:0016043;regulation of cell cycle#GO:0051726;ribonucleoprotein complex biogenesis#GO:0022613;chromatin remodeling#GO:0006338;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;establishment of organelle localization#GO:0051656;ribosomal small subunit biogenesis#GO:0042274;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;regulation of cell cycle process#GO:0010564;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000002330.3|UniProtKB=G3QIS6 G3QIS6 LOC101129624 PTHR11349:SF116 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776 nucleoside triphosphate biosynthetic process#GO:0009142;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;cellular process#GO:0009987;nucleoside triphosphate metabolic process#GO:0009141;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137;transferase#PC00220 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 GORGO|Ensembl=ENSGGOG00000007494.3|UniProtKB=G3QX02 G3QX02 HASPIN PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE HASPIN protein serine/threonine kinase activity#GO:0004674;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell cycle#GO:0007049 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000038667.1|UniProtKB=A0A2I2Z4D2 A0A2I2Z4D2 PAQR8 PTHR20855:SF22 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR BETA transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;lipid binding#GO:0008289;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;steroid binding#GO:0005496;signaling receptor activity#GO:0038023 response to endogenous stimulus#GO:0009719;response to steroid hormone#GO:0048545;response to hormone#GO:0009725;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to lipid#GO:0033993 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008770.3|UniProtKB=A0A2I2ZPC2 A0A2I2ZPC2 PITX2 PTHR45882:SF4 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>PITX#P06722 GORGO|Ensembl=ENSGGOG00000013418.3|UniProtKB=G3RC69 G3RC69 PTHR24173:SF16 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 24 sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012768.3|UniProtKB=G3RAH7 G3RAH7 OIT3 PTHR14002:SF18 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ONCOPROTEIN-INDUCED TRANSCRIPT 3 PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010257.3|UniProtKB=G3R443 G3R443 GOLGB1 PTHR18887:SF2 GOLGI-ASSOCIATED PROTEIN GCP360-RELATED GOLGIN SUBFAMILY B MEMBER 1 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000026042.2|UniProtKB=G3S139 G3S139 CCDC126 PTHR46941:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 126 COILED-COIL DOMAIN-CONTAINING PROTEIN 126 GORGO|Ensembl=ENSGGOG00000041901.1|UniProtKB=Q0MQF8 Q0MQF8 NDUFC2 PTHR13099:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B14.5B NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C2-RELATED respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000011656.3|UniProtKB=G3R7M5 G3R7M5 CALHM1 PTHR32261:SF2 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 1 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000013461.3|UniProtKB=G3RCA3 G3RCA3 LOC101135498 PTHR21191:SF8 AQUAPORIN AQUAPORIN-12A-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of cellular component size#GO:0032535;cellular process#GO:0009987;cellular component organization#GO:0016043;intracellular chemical homeostasis#GO:0055082;regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;regulation of anatomical structure size#GO:0090066 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000041320.1|UniProtKB=A0A2I2YBN8 A0A2I2YBN8 PTHR10366:SF671 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3-BETA HYDROXYSTEROID DEHYDROGENASE_ISOMERASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;steroid biosynthetic process#GO:0006694;regulation of biological quality#GO:0065008 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 lyase#PC00144;dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000008690.3|UniProtKB=G3R022 G3R022 LOC101140413 PTHR23425:SF7 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME N2-RELATED transporter#PC00227 GORGO|Ensembl=ENSGGOG00000009305.3|UniProtKB=G3R1L9 G3R1L9 ERAP1 PTHR11533:SF156 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171;catabolic process#GO:0009056 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000042830.1|UniProtKB=A0A2I2YGI6 A0A2I2YGI6 PTHR11885:SF20 RIBOSOMAL PROTEIN S15P/S13E SMALL RIBOSOMAL SUBUNIT PROTEIN US15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small-subunit processome#GO:0032040;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004140.3|UniProtKB=G3QNE8 G3QNE8 MATN4 PTHR24020:SF14 COLLAGEN ALPHA MATRILIN-4 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000005695.3|UniProtKB=G3QSE7 G3QSE7 IFT56 PTHR14781:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 56 INTRAFLAGELLAR TRANSPORT PROTEIN 56 binding#GO:0005488;protein-containing complex binding#GO:0044877 microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;intraciliary transport involved in cilium assembly#GO:0035735;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043 ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000010172.3|UniProtKB=G3R3U1 G3R3U1 LSM7 PTHR10553:SF44 SMALL NUCLEAR RIBONUCLEOPROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;U6 snRNP#GO:0005688;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000040324.1|UniProtKB=A0A2I2ZA94 A0A2I2ZA94 LRCOL1 PTHR10041:SF10 COLIPASE LEUCINE-RICH COLIPASE-LIKE PROTEIN 1 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000003702.3|UniProtKB=A0A2I2ZFU2 A0A2I2ZFU2 PTHR19134:SF206 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000002374.3|UniProtKB=G3S3T3 G3S3T3 PTHR11442:SF92 HEMOGLOBIN FAMILY MEMBER SUBFAMILY NOT NAMED tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488 multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;cellular process#GO:0009987;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;localization#GO:0051179;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;cell development#GO:0048468;homeostatic process#GO:0042592;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 globin#PC00107;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000043492.1|UniProtKB=G3QMR5 G3QMR5 LOC101147362 PTHR24302:SF31 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A7 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 steroid metabolic process#GO:0008202;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000023570.2|UniProtKB=G3S3H0 G3S3H0 PTHR11716:SF4 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP 10 SECRETORY PHOSPHOLIPASE A2 phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;ion binding#GO:0043167;small molecule binding#GO:0036094;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289 cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000041402.1|UniProtKB=G3S6R7 G3S6R7 PTHR23266:SF113 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000001283.3|UniProtKB=G3QG17 G3QG17 VSX1 PTHR24323:SF3 CEH-10 HOMEODOMAIN-CONTAINING HOMOLOG VISUAL SYSTEM HOMEOBOX 1 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007869.3|UniProtKB=G3QXY4 G3QXY4 RBM10 PTHR13948:SF4 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 10 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000013919.3|UniProtKB=G3RDI1 G3RDI1 EIF4G1 PTHR23253:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1 RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000041631.1|UniProtKB=A0A2I2YE36 A0A2I2YE36 PTHR24229:SF20 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 5 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;binding#GO:0005488;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089 regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular response to steroid hormone stimulus#GO:0071383;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;regulation of insulin secretion#GO:0050796;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of hormone secretion#GO:0046883;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of protein transport#GO:0051223;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;biological regulation#GO:0065007;regulation of establishment of protein localization#GO:0070201;regulation of secretion#GO:0051046;cell communication#GO:0007154;response to steroid hormone#GO:0048545;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of protein secretion#GO:0050708;neuropeptide signaling pathway#GO:0007218 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000000236.3|UniProtKB=A0A2I2ZMX7 A0A2I2ZMX7 CWC27 PTHR45625:SF6 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG catalytic activity, acting on a protein#GO:0140096;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000001927.3|UniProtKB=A0A2I2Y2E4 A0A2I2Y2E4 LY6H PTHR32217:SF5 LYMPHOCYTE ANTIGEN 6H LYMPHOCYTE ANTIGEN 6H acetylcholine receptor regulator activity#GO:0030548;acetylcholine receptor inhibitor activity#GO:0030550;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;neurotransmitter receptor regulator activity#GO:0099602;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;response to chemical#GO:0042221;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001892.3|UniProtKB=G3QHN3 G3QHN3 CABIN1 PTHR15502:SF7 CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED CALCINEURIN-BINDING PROTEIN CABIN-1 chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 phosphatase inhibitor#PC00183 GORGO|Ensembl=ENSGGOG00000034870.2|UniProtKB=G3SKD7 G3SKD7 PTHR14167:SF62 SH3 DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE SH3RF3 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;molecular adaptor activity#GO:0060090;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein-macromolecule adaptor activity#GO:0030674;acyltransferase activity#GO:0016746 positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001576.3|UniProtKB=G3QGT9 G3QGT9 IQCC PTHR16049:SF8 IQ DOMAIN-CONTAINING PROTEIN C IQ DOMAIN-CONTAINING PROTEIN C GORGO|Ensembl=ENSGGOG00000004857.3|UniProtKB=G3QQ97 G3QQ97 PTHR10285:SF143 URIDINE KINASE NICOTINAMIDE RIBOSIDE KINASE 2 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000002445.3|UniProtKB=G3QJ24 G3QJ24 PTHR23333:SF16 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 2A protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 regulation of cellular response to stress#GO:0080135;spindle localization#GO:0051653;cellular localization#GO:0051641;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;establishment or maintenance of cell polarity#GO:0007163;negative regulation of metabolic process#GO:0009892;establishment of organelle localization#GO:0051656;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of mitotic spindle localization#GO:0040001;regulation of protein metabolic process#GO:0051246;organelle organization#GO:0006996;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;organelle localization#GO:0051640;negative regulation of protein metabolic process#GO:0051248;regulation of ERAD pathway#GO:1904292;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;regulation of response to endoplasmic reticulum stress#GO:1905897;modification-dependent protein catabolic process#GO:0019941;establishment of cell polarity#GO:0030010;microtubule cytoskeleton organization involved in mitosis#GO:1902850;primary metabolic process#GO:0044238;cell cycle#GO:0007049;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;mitotic cell cycle process#GO:1903047;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;establishment of spindle localization#GO:0051293;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;ATPase complex#GO:1904949 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000002126.3|UniProtKB=G3SH63 G3SH63 PNP PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;organophosphate biosynthetic process#GO:0090407;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;nucleotide metabolic process#GO:0009117 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248 GORGO|Ensembl=ENSGGOG00000014382.3|UniProtKB=G3REP0 G3REP0 MBOAT1 PTHR13906:SF6 PORCUPINE MEMBRANE-BOUND GLYCEROPHOSPHOLIPID O-ACYLTRANSFERASE 1 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid modification#GO:0030258 membrane#GO:0016020;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000005413.3|UniProtKB=G3QRN8 G3QRN8 PCYOX1L PTHR15944:SF2 FARNESYLCYSTEINE LYASE PRENYLCYSTEINE OXIDASE 1-LIKE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 lyase#PC00144;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000014993.3|UniProtKB=G3RG93 G3RG93 DHRS3 PTHR24322:SF483 PKSB SHORT-CHAIN DEHYDROGENASE_REDUCTASE 3 all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;terpenoid metabolic process#GO:0006721;regulation of signaling#GO:0023051;isoprenoid metabolic process#GO:0006720;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000012060.3|UniProtKB=G3R8P7 G3R8P7 FNDC9 PTHR37361:SF2 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 9 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 9 GORGO|Ensembl=ENSGGOG00000003265.3|UniProtKB=G3QL68 G3QL68 LOC101127591 PTHR12694:SF7 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 transcription coregulator activity#GO:0003712;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046 transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352 transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 GORGO|Ensembl=ENSGGOG00000016141.3|UniProtKB=G3RJ66 G3RJ66 HACD4 PTHR11035:SF16 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 4 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000009989.3|UniProtKB=G3R3C5 G3R3C5 LOC101138215 PTHR14569:SF0 LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER G6E LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER G6E (PSEUDOGENE) signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;acetylcholine receptor regulator activity#GO:0030548;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;neurotransmitter receptor regulator activity#GO:0099602;molecular function activator activity#GO:0140677 response to nitrogen compound#GO:1901698;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;negative regulation of response to stimulus#GO:0048585;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000014271.3|UniProtKB=G3REE0 G3REE0 CD2BP2 PTHR13138:SF3 PROTEIN LIN1 CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2 protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000043951.1|UniProtKB=A0A2I2Z5D6 A0A2I2Z5D6 IER2 PTHR15895:SF4 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 2 PROTEIN GORGO|Ensembl=ENSGGOG00000022748.2|UniProtKB=G3RQX6 G3RQX6 WFDC11 PTHR19441:SF12 WAP four-disulfide core domain protein PROTEIN WFDC11 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000011117.3|UniProtKB=G3R692 G3R692 LYZ PTHR11407:SF28 LYSOZYME C LYSOZYME C hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;lysozyme activity#GO:0003796;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000011774.3|UniProtKB=G3R7Y6 G3R7Y6 SETD7 PTHR46820:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD7 HISTONE-LYSINE N-METHYLTRANSFERASE SETD7 protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;heterochromatin organization#GO:0070828;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000017033.3|UniProtKB=G3RLH8 G3RLH8 VASH1 PTHR15750:SF5 VASOHIBIN-1-LIKE ISOFORM X2 TUBULINYL-TYR CARBOXYPEPTIDASE 1 regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239;regulation of vasculature development#GO:1901342;regulation of angiogenesis#GO:0045765;regulation of anatomical structure morphogenesis#GO:0022603 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015832.3|UniProtKB=Q4QXU0 Q4QXU0 MRGPRX2 PTHR11334:SF70 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER X2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000006965.3|UniProtKB=G3QVN4 G3QVN4 ZNF568 PTHR24381:SF487 ZINC FINGER PROTEIN MHCY REGION ZINC FINGER PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008953.3|UniProtKB=G3R0R5 G3R0R5 SNX5 PTHR45850:SF5 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-5 protein binding#GO:0005515;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;cytoskeletal protein binding#GO:0008092 intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cytosolic transport#GO:0016482 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006368.3|UniProtKB=G3RYD0 G3RYD0 FOXA2 PTHR11829:SF167 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000004651.3|UniProtKB=G3QPQ9 G3QPQ9 CKMT1B PTHR11547:SF24 ARGININE OR CREATINE KINASE CREATINE KINASE U-TYPE, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;phosphorus metabolic process#GO:0006793 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 GORGO|Ensembl=ENSGGOG00000009211.3|UniProtKB=G3R1E0 G3R1E0 LOC101147625 PTHR14224:SF82 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 SUBFAMILY NOT NAMED ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462 GORGO|Ensembl=ENSGGOG00000003740.3|UniProtKB=G3QMD8 G3QMD8 KLHL23 PTHR24412:SF304 KELCH PROTEIN KELCH-LIKE PROTEIN 23 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014868.3|UniProtKB=A0A2I2ZVK3 A0A2I2ZVK3 PALM PTHR10498:SF6 PARALEMMIN-RELATED PARALEMMIN-1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal adaptor activity#GO:0008093 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;system development#GO:0048731;regulation of cell projection assembly#GO:0060491;cell communication#GO:0007154;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell projection organization#GO:0031344;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of filopodium assembly#GO:0051489;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of cellular component organization#GO:0051130;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;nervous system development#GO:0007399;positive regulation of cellular component biogenesis#GO:0044089;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 plasma membrane region#GO:0098590;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;synaptic membrane#GO:0097060;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cell projection#GO:0042995;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;intracellular anatomical structure#GO:0005622;filopodium#GO:0030175;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000044210.1|UniProtKB=A0A2I2YMQ1 A0A2I2YMQ1 PTHR23389:SF12 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CYTOKINE RECEPTOR-LIKE FACTOR 3 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000017021.3|UniProtKB=G3RLG9 G3RLG9 ADAM28 PTHR11905:SF32 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 28 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000026786.2|UniProtKB=A0A2I2Y5N2 A0A2I2Y5N2 PTHR16200:SF9 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ARKADIA N-TERMINAL DOMAIN-CONTAINING PROTEIN aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000009580.3|UniProtKB=G3QHD7 G3QHD7 KLC1 PTHR45783:SF7 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 GORGO|Ensembl=ENSGGOG00000014265.3|UniProtKB=G3RED1 G3RED1 ALX4 PTHR24329:SF322 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARISTALESS-LIKE 4 transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000009161.3|UniProtKB=G3R195 G3R195 MED30 PTHR31705:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000026754.2|UniProtKB=G3SIT8 G3SIT8 MAFG PTHR10129:SF15 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFG DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of epithelial cell differentiation#GO:0030856;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000012086.3|UniProtKB=A0A2I2YQA5 A0A2I2YQA5 MON2 PTHR10663:SF333 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PROTEIN MON2 HOMOLOG cytosolic transport#GO:0016482;protein localization to organelle#GO:0033365;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;protein localization to vacuole#GO:0072665;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000006453.3|UniProtKB=A0A2I2ZFB8 A0A2I2ZFB8 OFD1 PTHR15431:SF14 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTRIOLE AND CENTRIOLAR SATELLITE PROTEIN OFD1 cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001830.3|UniProtKB=G3QHH5 G3QHH5 SYTL2 PTHR45716:SF5 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000014109.3|UniProtKB=G3RDZ9 G3RDZ9 ATPSCKMT PTHR13610:SF8 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN ATP SYNTHASE SUBUNIT C LYSINE N-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 regulation of system process#GO:0044057;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000024469.2|UniProtKB=A0A2I2YRJ0 A0A2I2YRJ0 PTHR10701:SF13 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytoplasm#GO:0005737;U2 snRNP#GO:0005686;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type prespliceosome#GO:0071004;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000028274.2|UniProtKB=G3S3B3 G3S3B3 PTHR23077:SF117 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG B ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023549.2|UniProtKB=G3RSL7 G3RSL7 PTHR23193:SF15 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE-ASSOCIATED PROTEIN 1 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142;structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle envelope#GO:0031967 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002433.3|UniProtKB=G3QJ16 G3QJ16 PEBP4 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 GORGO|Ensembl=ENSGGOG00000023536.2|UniProtKB=G3RN89 G3RN89 NINJ1 PTHR12316:SF19 NINJURIN-RELATED NINJURIN-1 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 defense response#GO:0006952;inflammatory response#GO:0006954;cell adhesion#GO:0007155;response to stimulus#GO:0050896;response to stress#GO:0006950;programmed cell death#GO:0012501;cell death#GO:0008219;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000010770.3|UniProtKB=G3R5D3 G3R5D3 LOC101123909 PTHR11567:SF25 ACID PHOSPHATASE-RELATED PROTEIN FRA10AC1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000012236.3|UniProtKB=G3R956 G3R956 RASL10A PTHR46350:SF3 RAS LIKE FAMILY 10 MEMBER B-RELATED RAS-LIKE PROTEIN FAMILY MEMBER 10A GORGO|Ensembl=ENSGGOG00000010424.3|UniProtKB=G3RVV6 G3RVV6 ART5 PTHR10339:SF2 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5 glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009187.3|UniProtKB=G3R1C3 G3R1C3 FNTB PTHR11774:SF6 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000025191.2|UniProtKB=A0A2I2YZN9 A0A2I2YZN9 PTHR10351:SF54 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004646.3|UniProtKB=G3QPQ3 G3QPQ3 PUF60 PTHR47330:SF1 POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED POLY(U)-BINDING-SPLICING FACTOR PUF60 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;alternative mRNA splicing, via spliceosome#GO:0000380;protein-containing complex organization#GO:0043933 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000001910.3|UniProtKB=G3RY95 G3RY95 TMEM223 PTHR14549:SF2 TRANSMEMBRANE PROTEIN 223 TRANSMEMBRANE PROTEIN 223 GORGO|Ensembl=ENSGGOG00000007670.3|UniProtKB=G3QXG8 G3QXG8 LOC101129773 PTHR11206:SF81 MULTIDRUG RESISTANCE PROTEIN MULTIDRUG AND TOXIN EXTRUSION PROTEIN 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023213.2|UniProtKB=G3S0B1 G3S0B1 BTG3 PTHR22978:SF6 B-CELL TRANSLOCATION GENE PROTEIN BTG3 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000670.3|UniProtKB=G3QEG5 G3QEG5 MAP2K3 PTHR48013:SF21 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 3 catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>MKK3#P01367;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891;Apoptosis signaling pathway#P00006>MKK3#P00314;EGF receptor signaling pathway#P00018>MKK3,6#P00540;Integrin signalling pathway#P00034>MEK#P00925;Ras Pathway#P04393>MKK3/6#P04568;FGF signaling pathway#P00021>MKK3,6#P00625;Gonadotropin-releasing hormone receptor pathway#P06664>MKK3/6#P06805;p38 MAPK pathway#P05918>MKK3#P06036;Oxidative stress response#P00046>MKK3/6#P01121 GORGO|Ensembl=ENSGGOG00000026918.2|UniProtKB=G3SDQ0 G3SDQ0 PTHR12211:SF2 ENDOPLASMIC RETICULUM PROTEIN ERP29 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 29 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 gene expression#GO:0010467;protein maturation#GO:0051604;regulation of signal transduction#GO:0009966;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of response to stress#GO:0080134;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;protein folding#GO:0006457;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of response to endoplasmic reticulum stress#GO:1905897;protein metabolic process#GO:0019538;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006127.3|UniProtKB=G3RWV6 G3RWV6 STAT2 PTHR11801:SF41 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 2 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;immune response#GO:0006955;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;response to peptide hormone#GO:0043434;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;response to peptide#GO:1901652;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to hormone#GO:0009725;cell surface receptor signaling pathway via STAT#GO:0097696;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;cell surface receptor signaling pathway#GO:0007166 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 JAK/STAT signaling pathway#P00038>STAT#P01027;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;Interleukin signaling pathway#P00036>STAT#P00996 GORGO|Ensembl=ENSGGOG00000014390.3|UniProtKB=G3RRG0 G3RRG0 MFSD11 PTHR23294:SF0 ET TRANSLATION PRODUCT-RELATED UNC93-LIKE PROTEIN MFSD11 GORGO|Ensembl=ENSGGOG00000006972.2|UniProtKB=G3QVP1 G3QVP1 ZFP69 PTHR24381:SF74 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 69 HOMOLOG sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000023151.2|UniProtKB=G3RPL8 G3RPL8 PTHR11431:SF37 FERRITIN FERRITIN HEAVY CHAIN ferrous iron binding#GO:0008198;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 metal ion transport#GO:0030001;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000008335.3|UniProtKB=A0A2I2ZYE6 A0A2I2ZYE6 PTHR23113:SF223 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL-GDS-RELATED PROTEIN molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000013366.3|UniProtKB=G3RC17 G3RC17 CCR4 PTHR10489:SF608 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 4 protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 locomotion#GO:0040011;signaling#GO:0023052;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000037298.1|UniProtKB=A0A2I2Z7G8 A0A2I2Z7G8 PTHR10030:SF45 ALPHA-L-FUCOSIDASE PLASMA ALPHA-L-FUCOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glycosyl compound catabolic process#GO:1901658;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975 hydrolase#PC00121;glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000004465.3|UniProtKB=G3QP85 G3QP85 NPY5R PTHR24241:SF139 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 5 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025936.2|UniProtKB=G3SHT3 G3SHT3 PPP1R1C PTHR15417:SF5 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1C protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;phosphatase inhibitor#PC00183;phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000039323.1|UniProtKB=A0A2I2Z0L3 A0A2I2Z0L3 RNF128 PTHR22765:SF30 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF128 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endosome#GO:0005768;organelle#GO:0043226;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000014521.3|UniProtKB=A0A2I2YKJ9 A0A2I2YKJ9 GABRB2 PTHR18945:SF916 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-2 monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;monoatomic anion channel activity#GO:0005253 trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 signaling receptor complex#GO:0043235;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000015363.3|UniProtKB=G3RH75 G3RH75 CYP4A22 PTHR24291:SF215 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4A11-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;developmental process#GO:0032502;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;kidney development#GO:0001822;long-chain fatty acid metabolic process#GO:0001676;renal system development#GO:0072001;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;multicellular organismal process#GO:0032501;icosanoid metabolic process#GO:0006690;animal gross anatomical part developmental process#GO:0160108;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;system development#GO:0048731;anatomical structure development#GO:0048856;arachidonate metabolic process#GO:0019369;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007339.3|UniProtKB=A0A2I2Z858 A0A2I2Z858 PTHR11783:SF274 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4A1 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000040698.1|UniProtKB=A0A2I2YID8 A0A2I2YID8 PTHR11426:SF247 HISTONE H3 HISTONE H3.3C-LIKE kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;organelle localization#GO:0051640;nuclear division#GO:0000280;localization#GO:0051179;kinetochore organization#GO:0051383;organelle fission#GO:0048285;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;mitotic cell cycle process#GO:1903047;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;chromosome localization#GO:0050000;cellular component assembly#GO:0022607 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 GORGO|Ensembl=ENSGGOG00000010056.3|UniProtKB=G3R3I7 G3R3I7 LNX1 PTHR19964:SF14 MULTIPLE PDZ DOMAIN PROTEIN E3 UBIQUITIN-PROTEIN LIGASE LNX catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Notch signaling pathway#P00045>LNXp80#P01111 GORGO|Ensembl=ENSGGOG00000007964.3|UniProtKB=G3QY65 G3QY65 EPHA2 PTHR24416:SF306 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;angiogenesis#GO:0001525;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014576.3|UniProtKB=G3RF63 G3RF63 DDOST PTHR10830:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000025769.2|UniProtKB=G3SIE9 G3SIE9 PTHR48112:SF23 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B3 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000009949.3|UniProtKB=G3R389 G3R389 LOC101140568 PTHR48002:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007250.3|UniProtKB=G3QMF6 G3QMF6 PTHR24406:SF11 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED DNA-BINDING PROTEIN REPIN1 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000011308.3|UniProtKB=G3R6R1 G3R6R1 ANKRD13D PTHR12447:SF2 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13D protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of endocytosis#GO:0030100 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;late endosome#GO:0005770;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008931.3|UniProtKB=G3R0N9 G3R0N9 LDAF1 PTHR14275:SF0 PROMETHIN LIPID DROPLET ASSEMBLY FACTOR 1 GORGO|Ensembl=ENSGGOG00000009209.3|UniProtKB=G3R1D9 G3R1D9 HAO2 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000042231.1|UniProtKB=A0A2I2YFH5 A0A2I2YFH5 PCGF5 PTHR45893:SF1 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 5 regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000016798.3|UniProtKB=G3RKV6 G3RKV6 ZUP1 PTHR24403:SF82 ZINC FINGER PROTEIN ZINC FINGER-CONTAINING UBIQUITIN PEPTIDASE 1 double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000041843.1|UniProtKB=A0A2I2ZLW7 A0A2I2ZLW7 TMEM65 PTHR21706:SF16 TRANSMEMBRANE PROTEIN 65 TRANSMEMBRANE PROTEIN 65 regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;system development#GO:0048731;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;regulation of system process#GO:0044057 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002241.3|UniProtKB=G3QIJ6 G3QIJ6 BCL7A PTHR12767:SF11 BCL7 RELATED B-CELL CLL_LYMPHOMA 7 PROTEIN FAMILY MEMBER A cell surface receptor signaling pathway#GO:0007166;Notch signaling pathway#GO:0007219;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000014921.3|UniProtKB=G3RG23 G3RG23 C2H3orf18 PTHR15868:SF0 SIMILAR TO RIKEN CDNA 6430571L13 GENE, SIMILAR TO G20 PROTEIN SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 18 GORGO|Ensembl=ENSGGOG00000014926.3|UniProtKB=A0A2I2ZZ01 A0A2I2ZZ01 SNX12 PTHR45963:SF3 RE52028P SORTING NEXIN-12 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;early endosome membrane#GO:0031901;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000003882.3|UniProtKB=G3QMR4 G3QMR4 SLC18A1 PTHR23506:SF31 GH10249P CHROMAFFIN GRANULE AMINE TRANSPORTER solute:sodium symporter activity#GO:0015370;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;chloride transmembrane transporter activity#GO:0015108;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291 localization#GO:0051179;vesicle-mediated transport in synapse#GO:0099003;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular vesicle#GO:0097708;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;neuron projection terminus#GO:0044306;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;organelle membrane#GO:0031090;axon terminus#GO:0043679 secondary carrier transporter#PC00258;transporter#PC00227 5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410;5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418 GORGO|Ensembl=ENSGGOG00000017182.3|UniProtKB=G3RLV7 G3RLV7 MCHR2 PTHR24229:SF88 NEUROPEPTIDES RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 2 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;peptide binding#GO:0042277;neuropeptide binding#GO:0042923 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000000029.2|UniProtKB=G3QCT2 G3QCT2 BIK PTHR15018:SF1 BCL-2-INTERACTING KILLER BCL-2-INTERACTING KILLER regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Apoptosis signaling pathway#P00006>Blk#P00290;Apoptosis signaling pathway#P00006>Bik#P00258 GORGO|Ensembl=ENSGGOG00000016177.3|UniProtKB=G3RJ99 G3RJ99 SLPI PTHR19441:SF44 WAP four-disulfide core domain protein ANTILEUKOPROTEINASE endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Gene=OR3A1|UniProtKB=Q9TU89 Q9TU89 OR3A1 PTHR26452:SF740 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000003428.3|UniProtKB=G3QLL3 G3QLL3 EIF3D PTHR12399:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000015504.3|UniProtKB=A0A2I2Z792 A0A2I2Z792 ZC3HC1 PTHR15835:SF6 NUCLEAR-INTERACTING PARTNER OF ALK ZINC FINGER C3HC-TYPE PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005268.3|UniProtKB=A0A2I2ZJR9 A0A2I2ZJR9 CNBD1 PTHR23011:SF32 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000015528.3|UniProtKB=G3SAC9 G3SAC9 ZNF326 PTHR12190:SF1 A-KINASE ANCHOR PROTEIN AKAP 8 DBIRD COMPLEX SUBUNIT ZNF326 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription elongation#GO:0032784;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000038272.1|UniProtKB=A0A2I2YQB0 A0A2I2YQB0 TSLP PTHR38003:SF1 THYMIC STROMAL LYMPHOPOIETIN THYMIC STROMAL LYMPHOPOIETIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125 regulation of cytokine-mediated signaling pathway#GO:0001959;positive regulation of response to external stimulus#GO:0032103;positive regulation of inflammatory response#GO:0050729;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of response to cytokine stimulus#GO:0060759;positive regulation of cytokine-mediated signaling pathway#GO:0001961;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of signaling#GO:0023051;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of biosynthetic process#GO:0009891;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of cell communication#GO:0010646;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;positive regulation of signal transduction#GO:0009967 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000041655.1|UniProtKB=A0A2I2YQJ0 A0A2I2YQJ0 PTHR24341:SF1 HOMEOBOX PROTEIN ENGRAILED CYTOPLASMIC POLYADENYLATED HOMEOBOX-LIKE PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000039320.1|UniProtKB=A0A2I2YWT4 A0A2I2YWT4 UBL4B PTHR47905:SF1 UBIQUITIN-LIKE PROTEIN 4B UBIQUITIN-LIKE PROTEIN 4B GORGO|Ensembl=ENSGGOG00000001055.3|UniProtKB=G3QFG7 G3QFG7 TBPL2 PTHR10126:SF37 TATA-BOX BINDING PROTEIN TATA BOX-BINDING PROTEIN-LIKE 2 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription initiation#GO:0006352;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 GORGO|Ensembl=ENSGGOG00000008218.3|UniProtKB=G3QYU1 G3QYU1 MSRA PTHR42799:SF2 MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 reductase#PC00198;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000826.3|UniProtKB=G3QEW1 G3QEW1 TBXAS1 PTHR24301:SF17 THROMBOXANE-A SYNTHASE THROMBOXANE-A SYNTHASE catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 metabolite interconversion enzyme#PC00262;isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000007150.3|UniProtKB=G3QW46 G3QW46 TRAF2 PTHR10131:SF21 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 2 protein-macromolecule adaptor activity#GO:0030674;acyltransferase activity#GO:0016746;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;ubiquitin-protein transferase activity#GO:0004842;molecular adaptor activity#GO:0060090;transferase activity#GO:0016740;catalytic activity#GO:0003824;tumor necrosis factor receptor superfamily binding#GO:0032813;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;response to peptide#GO:1901652;tumor necrosis factor-mediated signaling pathway#GO:0033209;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to cytokine#GO:0034097;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to tumor necrosis factor#GO:0034612;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of intracellular signal transduction#GO:1902533 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 scaffold/adaptor protein#PC00226 p53 pathway#P00059>TRAF#P04620;Apoptosis signaling pathway#P00006>TRAF2#P00306 GORGO|Ensembl=ENSGGOG00000039207.1|UniProtKB=A0A2I2YCB4 A0A2I2YCB4 NUDT13 PTHR11383:SF3 NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 13 NAD(P)H PYROPHOSPHATASE NUDT13, MITOCHONDRIAL GORGO|Ensembl=ENSGGOG00000014922.3|UniProtKB=G3RG22 G3RG22 GNG11 PTHR13809:SF1 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-11 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 catalytic complex#GO:1902494;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 heterotrimeric G-protein#PC00117 Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;GABA-B receptor II signaling#P05731>Ggamma#P05754;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408 GORGO|Ensembl=ENSGGOG00000008739.3|UniProtKB=G3R069 G3R069 LAS1L PTHR15002:SF0 RIBOSOMAL BIOGENESIS PROTEIN LAS1L RIBOSOMAL BIOGENESIS PROTEIN LAS1L catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000011046.3|UniProtKB=A0A2I2ZS69 A0A2I2ZS69 PTHR45920:SF3 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FH1_FH2 DOMAIN-CONTAINING PROTEIN 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 anatomical structure development#GO:0048856;system development#GO:0048731;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;regulation of supramolecular fiber organization#GO:1902903;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;positive regulation of actin filament bundle assembly#GO:0032233;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;circulatory system development#GO:0072359;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;actomyosin structure organization#GO:0031032;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;striated muscle tissue development#GO:0014706;positive regulation of cellular component biogenesis#GO:0044089;heart development#GO:0007507;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cardiac muscle cell differentiation#GO:0055007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007797.3|UniProtKB=A0A2I2ZN18 A0A2I2ZN18 PID1 PTHR16265:SF1 PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN regulation of reactive oxygen species metabolic process#GO:2000377;negative regulation of cellular process#GO:0048523;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000000975.3|UniProtKB=G3SHL8 G3SHL8 ARHGEF19 PTHR12845:SF6 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 19 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 response to stress#GO:0006950;response to wounding#GO:0009611;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;wound healing#GO:0042060 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000004848.3|UniProtKB=G3S3J4 G3S3J4 RUNX3 PTHR11950:SF43 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 nervous system development#GO:0007399;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;skeletal system development#GO:0001501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;hemopoiesis#GO:0030097;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;tissue development#GO:0009888;chondrocyte differentiation#GO:0002062;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;connective tissue development#GO:0061448;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;ossification#GO:0001503;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;cartilage development#GO:0051216;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;Runt transcription factor#PC00254 GORGO|Ensembl=ENSGGOG00000043652.1|UniProtKB=A0A2I2YWB7 A0A2I2YWB7 PRODH2 PTHR13914:SF29 PROLINE OXIDASE HYDROXYPROLINE DEHYDROGENASE catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;anion binding#GO:0043168 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidase#PC00175 Huntington disease#P00029>Proline oxidase#G01529 GORGO|Ensembl=ENSGGOG00000004023.3|UniProtKB=A0A2I2ZXG0 A0A2I2ZXG0 CD8A PTHR10441:SF2 CD8 ALPHA CHAIN T-CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN cell development#GO:0048468;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;mononuclear cell differentiation#GO:1903131;regulation of biological process#GO:0050789;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune system process#GO:0002376;T cell differentiation#GO:0030217;lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell activation#GO:0001775;regulation of immune response#GO:0050776;T cell mediated immunity#GO:0002456;lymphocyte differentiation#GO:0030098;adaptive immune response#GO:0002250;hemopoiesis#GO:0030097;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;developmental process#GO:0032502;T cell receptor signaling pathway#GO:0050852 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000015067.3|UniProtKB=A0A2I2YUN1 A0A2I2YUN1 MORC2 PTHR23337:SF7 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1 ATPASE MORC2 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Gene=KCNS1|UniProtKB=A4K2R3 A4K2R3 KCNS1 PTHR11537:SF61 VOLTAGE-GATED POTASSIUM CHANNEL DELAYED-RECTIFIER POTASSIUM CHANNEL REGULATORY SUBUNIT KCNS1 ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;action potential#GO:0001508;metal ion transport#GO:0030001 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000015642.3|UniProtKB=G3RHY6 G3RHY6 SENP2 PTHR12606:SF11 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 2 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 protease#PC00190 GORGO|Ensembl=ENSGGOG00000016647.3|UniProtKB=G3RKH9 G3RKH9 KIAA0513 PTHR13663:SF2 SIMILAR TO RIKEN CDNA 6430548M08 RIKEN CDNA 6430548M08 GENE LIKE GORGO|Ensembl=ENSGGOG00000036607.1|UniProtKB=A0A2I2YYY5 A0A2I2YYY5 BDNF PTHR11589:SF3 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIC FACTOR BDNF PRECURSOR FORM molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;negative regulation of neuron apoptotic process#GO:0043524;neuron projection development#GO:0031175;regulation of neuron apoptotic process#GO:0043523;nervous system development#GO:0007399;regulation of trans-synaptic signaling#GO:0099177;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular response to nerve growth factor stimulus#GO:1990090;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular response to growth factor stimulus#GO:0071363 synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;exocytic vesicle#GO:0070382;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell junction#GO:0030054 neurotrophic factor#PC00163;growth factor#PC00112 Metabotropic glutamate receptor group II pathway#P00040>BDNF#G01540;Huntington disease#P00029>BDNF#G01531;Huntington disease#P00029>BDNF#P00795 GORGO|Ensembl=ENSGGOG00000015219.3|UniProtKB=A0A2I2ZQW1 A0A2I2ZQW1 TRIM31 PTHR24103:SF87 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM31 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011378.3|UniProtKB=G3R6X2 G3R6X2 CETN2 PTHR23050:SF305 CALCIUM BINDING PROTEIN CENTRIN-2 calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 organelle assembly#GO:0070925;centriole replication#GO:0007099;cellular response to stress#GO:0033554;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000036311.1|UniProtKB=G3S148 G3S148 CHMP3 PTHR10476:SF1 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 3 macromolecule localization#GO:0033036;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;late endosome to vacuole transport#GO:0045324;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000023681.2|UniProtKB=G3SGS9 G3SGS9 DUSP3 PTHR45682:SF1 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 3 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 positive regulation of mitotic cell cycle#GO:0045931;negative regulation of cell activation#GO:0050866;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;regulation of cell adhesion#GO:0030155;negative regulation of response to stimulus#GO:0048585;negative regulation of cell adhesion#GO:0007162;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;regulation of immune response#GO:0050776;negative regulation of T cell activation#GO:0050868;regulation of cell communication#GO:0010646;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of MAPK cascade#GO:0043409;negative regulation of multicellular organismal process#GO:0051241;regulation of JNK cascade#GO:0046328;regulation of MAPK cascade#GO:0043408;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;positive regulation of cell cycle#GO:0045787;negative regulation of signal transduction#GO:0009968;negative regulation of leukocyte activation#GO:0002695;regulation of T cell activation#GO:0050863;negative regulation of cell-cell adhesion#GO:0022408;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of lymphocyte activation#GO:0051249;regulation of cell cycle#GO:0051726;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000037318.1|UniProtKB=A0A2I2YUN9 A0A2I2YUN9 PTHR23266:SF338 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-20 antigen binding#GO:0003823;binding#GO:0005488 immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010055.3|UniProtKB=G3R3I8 G3R3I8 GRM2 PTHR24060:SF147 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 2 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Ionotropic glutamate receptor pathway#P00037>mGluR 2/3#P01014;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Metabotropic glutamate receptor group II pathway#P00040>mGluR2/3#P01048 GORGO|Ensembl=ENSGGOG00000003073.3|UniProtKB=G3QKP5 G3QKP5 PTHR15464:SF1 TRANSCRIPTION FACTOR 19 TRANSCRIPTION FACTOR 19 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015029.3|UniProtKB=G3RGC5 G3RGC5 LOC101138267 PTHR26450:SF170 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E8 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016965.3|UniProtKB=G3RLB7 G3RLB7 FASTKD1 PTHR21228:SF29 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;regulation of RNA stability#GO:0043487;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA metabolic process#GO:1903311;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000001979.3|UniProtKB=G3QHW0 G3QHW0 DCSTAMP PTHR21041:SF2 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN osteoclast differentiation#GO:0030316;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;cell-cell fusion#GO:0140253;fertilization#GO:0009566;cell development#GO:0048468;reproductive process#GO:0022414;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;leukocyte differentiation#GO:0002521;cellular developmental process#GO:0048869;developmental process#GO:0032502;hemopoiesis#GO:0030097;cellular process#GO:0009987;single fertilization#GO:0007338 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cell surface#GO:0009986;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000011351.3|UniProtKB=G3R6U3 G3R6U3 SAPCD1 PTHR14907:SF4 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000026805.2|UniProtKB=G3SDH8 G3SDH8 GBE1 PTHR43651:SF15 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glucan biosynthetic process#GO:0009250;polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;glycogen biosynthetic process#GO:0005978;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 amylase#PC00048 GORGO|Ensembl=ENSGGOG00000025979.2|UniProtKB=G3S1V7 G3S1V7 FAM187B PTHR32178:SF8 FAM187 PROTEIN FAM187B immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000016359.3|UniProtKB=G3S562 G3S562 CT47C1 PTHR32157:SF0 GENE 6268-RELATED CANCER_TESTIS ANTIGEN FAMILY 47 MEMBER C1 GORGO|Ensembl=ENSGGOG00000007401.3|UniProtKB=G3RSR2 G3RSR2 TRMT61A PTHR12133:SF2 TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000014778.3|UniProtKB=G3RFR0 G3RFR0 DDX60L PTHR44533:SF1 DEAD/H RNA HELICASE, PUTATIVE-RELATED ATP-DEPENDENT RNA HELICASE DDX60-LIKE-RELATED double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 response to external stimulus#GO:0009605;defense response#GO:0006952;response to virus#GO:0009615;response to biotic stimulus#GO:0009607;defense response to virus#GO:0051607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000006334.3|UniProtKB=A0A2I2ZIZ8 A0A2I2ZIZ8 PTHR45817:SF2 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000043270.1|UniProtKB=A0A2I2ZHX7 A0A2I2ZHX7 PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3B enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000007377.3|UniProtKB=G3QWQ5 G3QWQ5 PTHR12210:SF173 DULLARD PROTEIN PHOSPHATASE CTD SMALL PHOSPHATASE-LIKE PROTEIN 2 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000039922.1|UniProtKB=A0A2I2YNW6 A0A2I2YNW6 LOC101140204 PTHR12062:SF32 N-ACETYLGLUCOSAMINYLTRANSFERASE VI MGAT4 FAMILY, MEMBER F glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000013735.3|UniProtKB=G3RD13 G3RD13 SMC4 PTHR43939:SF130 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 4 meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;mitotic cell cycle process#GO:1903047;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;nuclear division#GO:0000280;sexual reproduction#GO:0019953;organelle fission#GO:0048285;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;condensin complex#GO:0000796;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634 GORGO|Gene=NDUFB11|UniProtKB=Q0MQJ4 Q0MQJ4 NDUFB11 PTHR13327:SF0 NADH-UBIQUINONE OXIDOREDUCTASE ESSS SUBUNIT, MITOCHONDRIAL PRECURSOR NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 11, MITOCHONDRIAL catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000008632.3|UniProtKB=G3QZW6 G3QZW6 PDGFC PTHR11633:SF5 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR C protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;growth factor receptor binding#GO:0070851 cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of ERK1 and ERK2 cascade#GO:0070372;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224 GORGO|Ensembl=ENSGGOG00000006888.3|UniProtKB=G3QVH1 G3QVH1 PEMT PTHR15458:SF5 PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity#GO:0003824;transferase activity#GO:0016740 phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;phosphatidylcholine biosynthetic process#GO:0006656;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000009800.3|UniProtKB=G3R2W8 G3R2W8 HCFC1 PTHR46003:SF3 HOST CELL FACTOR HOST CELL FACTOR 1 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000039564.1|UniProtKB=A0A2I2YKT5 A0A2I2YKT5 PTHR11021:SF3 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F SM PROTEIN F nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000039966.1|UniProtKB=G3RQ60 G3RQ60 OR11G2 PTHR24242:SF183 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11G2 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016551.3|UniProtKB=G3RK91 G3RK91 AS3MT PTHR46254:SF7 PROTEIN GVQW1-RELATED MITOCHONDRIAL RIBOSOMAL PROTEIN L33 GORGO|Ensembl=ENSGGOG00000012213.3|UniProtKB=G3R937 G3R937 PTHR10476:SF17 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1A endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;late endosome to vacuole transport#GO:0045324 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015114.3|UniProtKB=G3QTZ8 G3QTZ8 PEDS1 PTHR48177:SF2 TRANSMEMBRANE PROTEIN 189 PLASMANYLETHANOLAMINE DESATURASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000013934.3|UniProtKB=G3S5A2 G3S5A2 PTHR11935:SF77 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE-LIKE PROTEIN thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 GORGO|Ensembl=ENSGGOG00000014954.3|UniProtKB=G3RG65 G3RG65 XPO7 PTHR12596:SF11 EXPORTIN 4,7-RELATED EXPORTIN-7 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641 intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016409.3|UniProtKB=G3RJX5 G3RJX5 ARAP3 PTHR45899:SF4 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;enzyme regulator activity#GO:0030234;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;phosphatidylinositol phosphate binding#GO:1901981;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of actin filament-based process#GO:0032970 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000016027.2|UniProtKB=G3RIW6 G3RIW6 OR6A2 PTHR24242:SF426 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000008364.3|UniProtKB=G3QZ72 G3QZ72 SPINT2 PTHR47247:SF1 KUNITZ-TYPE PROTEASE INHIBITOR 2 KUNITZ-TYPE PROTEASE INHIBITOR 2 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;cell development#GO:0048468;cell morphogenesis#GO:0000902;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cell differentiation#GO:0030154;epithelium development#GO:0060429;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000027851.2|UniProtKB=G3S1R4 G3S1R4 ANKRD40 PTHR24192:SF1 ANKYRIN REPEAT DOMAIN 40 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 40 GORGO|Ensembl=ENSGGOG00000027834.2|UniProtKB=G3RZ19 G3RZ19 LEUTX PTHR45793:SF18 HOMEOBOX PROTEIN PAIRED-LIKE HOMEODOMAIN TRANSCRIPTION FACTOR LEUTX DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000010404.3|UniProtKB=G3R4F3 G3R4F3 IWS1 PTHR46010:SF1 PROTEIN IWS1 HOMOLOG PROTEIN IWS1 HOMOLOG macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000014087.2|UniProtKB=G3RDX6 G3RDX6 LOC101147047 PTHR26453:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6Y1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011270.3|UniProtKB=G3R6M7 G3R6M7 FAM221B PTHR31214:SF3 PROTEIN FAM221A-RELATED PROTEIN FAM221B GORGO|Ensembl=ENSGGOG00000042048.1|UniProtKB=A0A2I2YK15 A0A2I2YK15 ACYP1 PTHR10029:SF3 ACYLPHOSPHATASE ACYLPHOSPHATASE-1 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000001529.3|UniProtKB=G3QGP8 G3QGP8 SLC25A21 PTHR46356:SF1 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012626.3|UniProtKB=G3RA65 G3RA65 SEMA3D PTHR11036:SF36 SEMAPHORIN SEMAPHORIN-3D signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell projection morphogenesis#GO:0048858;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;mesenchymal cell differentiation#GO:0048762;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;neural crest cell differentiation#GO:0014033;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;taxis#GO:0042330;neural crest cell migration#GO:0001755;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;chemotaxis#GO:0006935;stem cell development#GO:0048864;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;mesenchyme development#GO:0060485;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;tissue development#GO:0009888;cell migration#GO:0016477;multicellular organismal process#GO:0032501;neural crest cell development#GO:0014032;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon guidance#GO:0007411;stem cell differentiation#GO:0048863;axon development#GO:0061564 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000044023.1|UniProtKB=A0A2I2YG54 A0A2I2YG54 BMP10 PTHR11848:SF39 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 10 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000000791.3|UniProtKB=G3S5M9 G3S5M9 GABRA1 PTHR18945:SF514 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;animal gross anatomical part developmental process#GO:0160108;synapse assembly#GO:0007416;signaling#GO:0023052;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;chloride transport#GO:0006821;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;nervous system development#GO:0007399;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;anatomical structure development#GO:0048856;chloride transmembrane transport#GO:1902476;localization#GO:0051179;cell communication#GO:0007154;system development#GO:0048731;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 cell junction#GO:0030054;signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell projection membrane#GO:0031253;dendrite#GO:0030425;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000040154.1|UniProtKB=A0A2I2Z079 A0A2I2Z079 PTHR24070:SF395 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1A ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;intracellular signaling cassette#GO:0141124;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of neurotransmitter transport#GO:0051588;regulation of secretion by cell#GO:1903530;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular response to nitrogen compound#GO:1901699;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;intracellular signal transduction#GO:0035556;regulation of exocytosis#GO:0017157;response to nitrogen compound#GO:1901698;regulation of secretion#GO:0051046;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 GORGO|Ensembl=ENSGGOG00000022781.2|UniProtKB=G3S3K0 G3S3K0 SLC25A17 PTHR45939:SF5 PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED PEROXISOMAL MEMBRANE PROTEIN PMP34 purine nucleotide transmembrane transporter activity#GO:0015216;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000010883.3|UniProtKB=A0A2I2Z975 A0A2I2Z975 PFKFB4 PTHR10606:SF14 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;sugar-phosphatase activity#GO:0050308;phosphoric ester hydrolase activity#GO:0042578;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatase activity#GO:0016791 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydrolase#PC00121;carbohydrate phosphatase#PC00066;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000015470.3|UniProtKB=G3RHH4 G3RHH4 AFAP1L2 PTHR14338:SF4 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1-LIKE 2 protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;inflammatory response#GO:0006954;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;positive regulation of signal transduction#GO:0009967;regulation of ERBB signaling pathway#GO:1901184;positive regulation of macromolecule metabolic process#GO:0010604;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000009093.3|UniProtKB=G3R140 G3R140 SNCG PTHR13820:SF10 SYNUCLEIN GAMMA-SYNUCLEIN transition metal ion binding#GO:0046914;ion binding#GO:0043167;copper ion binding#GO:0005507;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;signaling#GO:0023052;cell junction organization#GO:0034330;endocytosis#GO:0006897;anterograde trans-synaptic signaling#GO:0098916;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;cellular localization#GO:0051641;localization#GO:0051179;cell communication#GO:0007154;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;axon#GO:0030424;neuronal cell body#GO:0043025;cell projection#GO:0042995;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell body#GO:0044297;axon terminus#GO:0043679;cell junction#GO:0030054;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;presynapse#GO:0098793;neuron projection#GO:0043005 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Parkinson disease#P00049>gamma-Synuclein#P01231 GORGO|Ensembl=ENSGGOG00000004944.3|UniProtKB=G3QQH9 G3QQH9 IGSF8 PTHR12207:SF22 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 8 membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000016074.3|UniProtKB=G3S9J5 G3S9J5 NCOA7 PTHR23354:SF68 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED NUCLEAR RECEPTOR COACTIVATOR 7 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;response to oxidative stress#GO:0006979;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000027857.2|UniProtKB=G3S5I4 G3S5I4 RNF138 PTHR46968:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF138 E3 UBIQUITIN-PROTEIN LIGASE RNF138 acyltransferase activity#GO:0016746;binding#GO:0005488;nucleic acid binding#GO:0003676;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;double-strand break repair via single-strand annealing#GO:0045002;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;site of double-strand break#GO:0035861 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000011128.3|UniProtKB=G3SD27 G3SD27 MRPL3 PTHR11229:SF13 50S RIBOSOMAL PROTEIN L3 LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012691.3|UniProtKB=G3RAB5 G3RAB5 MTFP1 PTHR11001:SF2 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 mitochondrion organization#GO:0007005;organelle fission#GO:0048285;mitochondrial fission#GO:0000266;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000003358.3|UniProtKB=A0A2I2Y9C6 A0A2I2Y9C6 MOB1B PTHR22599:SF63 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 1B kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;hippo signaling#GO:0035329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000022697.2|UniProtKB=G3SJR4 G3SJR4 SNIP1 PTHR23308:SF36 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 SMAD NUCLEAR-INTERACTING PROTEIN 1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 GORGO|Ensembl=ENSGGOG00000011670.3|UniProtKB=G3S636 G3S636 NEURL1 PTHR12429:SF13 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 localization#GO:0051179;regulation of nervous system development#GO:0051960;regulation of Notch signaling pathway#GO:0008593;regulation of developmental process#GO:0050793;modulation of chemical synaptic transmission#GO:0050804;positive regulation of neurogenesis#GO:0050769;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of neurogenesis#GO:0050767;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;regulation of neuronal synaptic plasticity#GO:0048168;establishment of localization#GO:0051234;positive regulation of developmental process#GO:0051094;transport#GO:0006810;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;regulation of synaptic plasticity#GO:0048167;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;protein transport#GO:0015031;regulation of signaling#GO:0023051;positive regulation of nervous system development#GO:0051962;endocytosis#GO:0006897;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;import into cell#GO:0098657;positive regulation of cell differentiation#GO:0045597;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;regulation of trans-synaptic signaling#GO:0099177;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184 membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;plasma membrane#GO:0005886;postsynaptic density#GO:0014069;cell junction#GO:0030054 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 GORGO|Ensembl=ENSGGOG00000038557.1|UniProtKB=A0A2I2YD15 A0A2I2YD15 PTHR31186:SF1 MODULATOR OF SMOOTHENED PROTEIN MODULATOR OF SMOOTHENED PROTEIN regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection membrane#GO:0031253;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000023632.2|UniProtKB=G3S8R9 G3S8R9 DAZL PTHR11176:SF4 BOULE-RELATED DELETED IN AZOOSPERMIA-LIKE translation regulator activity#GO:0045182 RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of protein metabolic process#GO:0051247;regulation of translational initiation#GO:0006446;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;positive regulation of translation#GO:0045727;negative regulation of catabolic process#GO:0009895;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000024775.2|UniProtKB=G3SG15 G3SG15 ENDOD1 PTHR21472:SF8 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN GORGO|Ensembl=ENSGGOG00000012406.3|UniProtKB=G3R9L8 G3R9L8 CMC1 PTHR22977:SF5 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000014637.3|UniProtKB=G3RFC2 G3RFC2 KRI1 PTHR14490:SF5 ZINC FINGER, ZZ TYPE PROTEIN KRI1 HOMOLOG ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000004003.3|UniProtKB=G3QN22 G3QN22 MAPK6 PTHR24055:SF171 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 6 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>MEK#P01402;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interleukin signaling pathway#P00036>ERK#P00965;Integrin signalling pathway#P00034>ERK#P00907 GORGO|Ensembl=ENSGGOG00000003131.3|UniProtKB=G3QKU4 G3QKU4 RBFA PTHR14725:SF0 RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED GORGO|Ensembl=ENSGGOG00000000416.3|UniProtKB=G3QDT3 G3QDT3 PARL PTHR43731:SF14 RHOMBOID PROTEASE PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000023498.2|UniProtKB=G3RQP7 G3RQP7 NIFK PTHR46754:SF1 MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013147.3|UniProtKB=G3RBG9 G3RBG9 SIRT3 PTHR11085:SF5 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;deacylase activity#GO:0160215;transferase activity#GO:0016740;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000024134.2|UniProtKB=G3S676 G3S676 IGLV7-43 PTHR23267:SF335 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 7-43 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000013724.3|UniProtKB=G3RMR4 G3RMR4 PTHR24147:SF29 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 62 GORGO|Ensembl=ENSGGOG00000014484.3|UniProtKB=G3REY5 G3REY5 DDX41 PTHR47958:SF103 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX41-RELATED RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000037514.1|UniProtKB=A0A2I2Y4S3 A0A2I2Y4S3 PTHR14256:SF6 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT NDUFA4 cytochrome complex#GO:0070069;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transporter complex#GO:1990351 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000004343.3|UniProtKB=G3QNY3 G3QNY3 AP1M1 PTHR10529:SF257 AP COMPLEX SUBUNIT MU AP-1 COMPLEX SUBUNIT MU-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;vacuolar transport#GO:0007034;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896 transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;trans-Golgi network transport vesicle membrane#GO:0012510;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;coated membrane#GO:0048475;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000008530.3|UniProtKB=G3QZN0 G3QZN0 PES1 PTHR12221:SF8 PESCADILLO - RELATED PESCADILLO HOMOLOG nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;binding#GO:0005488;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007615.3|UniProtKB=G3QXD1 G3QXD1 SPTAN1 PTHR11915:SF427 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000001458.3|UniProtKB=G3QGI4 G3QGI4 CENPT PTHR46904:SF1 CENTROMERE PROTEIN T CENTROMERE PROTEIN T mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049 GORGO|Ensembl=ENSGGOG00000009058.3|UniProtKB=G3R106 G3R106 TMEM220 PTHR34262:SF1 TRANSMEMBRANE PROTEIN 220 TRANSMEMBRANE PROTEIN 220 GORGO|Ensembl=ENSGGOG00000004560.3|UniProtKB=G3QPH4 G3QPH4 A4GNT PTHR12042:SF16 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 glycosphingolipid biosynthetic process#GO:0006688;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000038032.1|UniProtKB=G3QVF0 G3QVF0 CFL2 PTHR11913:SF15 COFILIN-RELATED COFILIN-2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;actin cytoskeleton organization#GO:0030036 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Cofilin#P00508 GORGO|Ensembl=ENSGGOG00000025249.2|UniProtKB=G3RP07 G3RP07 VOPP1 PTHR14971:SF2 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN BINDING PROTEIN VOPP1 molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vesicle membrane#GO:0012506;lysosomal membrane#GO:0005765 GORGO|Ensembl=ENSGGOG00000041950.1|UniProtKB=G3RAF3 G3RAF3 PTHR44830:SF1 ELONGATION FACTOR 1 ALPHA ELONGATION FACTOR 1-ALPHA 2-LIKE GORGO|Ensembl=ENSGGOG00000040568.1|UniProtKB=A0A2I2Y5D2 A0A2I2Y5D2 LOC101144883 PTHR12604:SF7 KU AUTOANTIGEN DNA HELICASE X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;telomeric repeat DNA binding#GO:0042162;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;chromosome organization#GO:0051276;telomere maintenance#GO:0000723 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA helicase#PC00011 GORGO|Ensembl=ENSGGOG00000002213.3|UniProtKB=G3QIG8 G3QIG8 HOXA3 PTHR45664:SF13 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-A3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;skeletal system development#GO:0001501;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development#GO:0009790;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000039309.1|UniProtKB=A0A2I2ZL72 A0A2I2ZL72 C11orf86 PTHR31831:SF1 HYPOTHETICAL PROTEIN LOC689065 SIMILAR TO HUMAN CHROMOSOME 11 OPEN READING FRAME 86 GORGO|Ensembl=ENSGGOG00000024883.2|UniProtKB=G3S4M5 G3S4M5 TMEM150C PTHR21324:SF7 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED TRANSMEMBRANE PROTEIN 150C cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000024321.2|UniProtKB=A0A2I2YKB5 A0A2I2YKB5 BAG2 PTHR12334:SF6 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000014012.3|UniProtKB=G3RQB8 G3RQB8 ATP11A PTHR24092:SF33 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IH intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215 lipid transport#GO:0006869;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876 recycling endosome#GO:0055037;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007433.3|UniProtKB=G3QWV4 G3QWV4 DVL3 PTHR10878:SF6 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447 GORGO|Ensembl=ENSGGOG00000009760.3|UniProtKB=G3RZP0 G3RZP0 AXIN1 PTHR46102:SF3 AXIN AXIN-1 binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;beta-catenin binding#GO:0008013;ubiquitin-like protein ligase binding#GO:0044389;identical protein binding#GO:0042802;ubiquitin protein ligase binding#GO:0031625 regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of Wnt signaling pathway#GO:0030111;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;anatomical structure development#GO:0048856;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178 cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>Axin#P01429;Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 GORGO|Ensembl=ENSGGOG00000025027.2|UniProtKB=G3S9D4 G3S9D4 ELP5 PTHR15641:SF1 ELONGATOR COMPLEX PROTEIN 5 ELONGATOR COMPLEX PROTEIN 5 RNA binding#GO:0003723;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;elongator holoenzyme complex#GO:0033588;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000025013.2|UniProtKB=G3S648 G3S648 SLC25A43 PTHR24089:SF246 SOLUTE CARRIER FAMILY 25 SOLUTE CARRIER FAMILY 25 MEMBER 43 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 GORGO|Ensembl=ENSGGOG00000008451.3|UniProtKB=G3QZE6 G3QZE6 PTHR22571:SF24 FILAGGRIN-RELATED FILAGGRIN-2 epithelium development#GO:0060429;tissue development#GO:0009888;skin development#GO:0043588;anatomical structure development#GO:0048856;animal organ development#GO:0048513;epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000014877.3|UniProtKB=G3RFY9 G3RFY9 SFSWAP PTHR13161:SF15 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;alternative mRNA splicing, via spliceosome#GO:0000380;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000010092.3|UniProtKB=G3R3M2 G3R3M2 NUP93 PTHR11225:SF4 NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP93 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 protein import into nucleus#GO:0006606;protein transport#GO:0015031;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;gene expression#GO:0010467;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle envelope#GO:0031967 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014454.3|UniProtKB=A0A2I2ZFW3 A0A2I2ZFW3 PTHR12210:SF3 DULLARD PROTEIN PHOSPHATASE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000003417.3|UniProtKB=G3QLK2 G3QLK2 LRPAP1 PTHR16560:SF2 ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;lipoprotein particle receptor binding#GO:0070325;protein binding#GO:0005515;enzyme binding#GO:0019899;signaling receptor binding#GO:0005102;binding#GO:0005488 negative regulation of cellular process#GO:0048523;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;negative regulation of cellular component organization#GO:0051129;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;cis-Golgi network#GO:0005801;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle lumen#GO:0070013;endosome#GO:0005768;intracellular organelle#GO:0043229;rough endoplasmic reticulum#GO:0005791;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle lumen#GO:0043233;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000008397.3|UniProtKB=A0A2I2YCJ1 A0A2I2YCJ1 IKBIP PTHR21734:SF11 INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN GORGO|Ensembl=ENSGGOG00000010290.3|UniProtKB=G3R465 G3R465 MMEL1 PTHR11733:SF141 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED MEMBRANE METALLO-ENDOPEPTIDASE-LIKE 1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000009857.3|UniProtKB=G3RPG5 G3RPG5 TRPV3 PTHR10582:SF6 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 3 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873 signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;cytoskeleton organization#GO:0007010;monoatomic cation transmembrane transport#GO:0098655;response to chemical#GO:0042221;calcium ion transport#GO:0006816;cellular component organization or biogenesis#GO:0071840;cellular response to chemical stress#GO:0062197;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;cellular response to abiotic stimulus#GO:0071214;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;cellular component organization#GO:0016043;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;response to stimulus#GO:0050896;import across plasma membrane#GO:0098739;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;response to osmotic stress#GO:0006970;transport#GO:0006810;actin filament organization#GO:0007015;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;calcium ion import#GO:0070509;osmosensory signaling pathway#GO:0007231;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cellular response to environmental stimulus#GO:0104004;actin filament-based process#GO:0030029;cellular response to osmotic stress#GO:0071470;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000000860.3|UniProtKB=A0A2I2YXM7 A0A2I2YXM7 HMBOX1 PTHR14618:SF0 HOMEODOX-CONTAINING PROTEIN 1 HMBOX1 HOMEOBOX-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000011592.3|UniProtKB=G3R7H8 G3R7H8 LRRC45 PTHR23170:SF3 NY-REN-58 ANTIGEN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 45 GORGO|Ensembl=ENSGGOG00000003373.3|UniProtKB=G3QLG3 G3QLG3 SDCBP2 PTHR12345:SF13 SYNTENIN RELATED SYNTENIN-2 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000005932.3|UniProtKB=A0A2I2YXS6 A0A2I2YXS6 SYT10 PTHR10024:SF46 SYNAPTOTAGMIN SYNAPTOTAGMIN-10 molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149 regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;chemical synaptic transmission#GO:0007268;regulation of transport#GO:0051049;regulation of localization#GO:0032879;establishment of localization#GO:0051234;transport#GO:0006810;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;synaptic signaling#GO:0099536 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000015567.3|UniProtKB=G3RHR1 G3RHR1 KCNH4 PTHR10217:SF630 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH4 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 cellular process#GO:0009987;metal ion transport#GO:0030001;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000017172.3|UniProtKB=G3RLU8 G3RLU8 FAM78A PTHR31655:SF3 PROTEIN FAM78A PROTEIN FAM78A GORGO|Ensembl=ENSGGOG00000036224.1|UniProtKB=A0A2I2Y4U2 A0A2I2Y4U2 CIPC PTHR34648:SF1 CLOCK-INTERACTING PACEMAKER CLOCK-INTERACTING PACEMAKER regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013501.3|UniProtKB=A0A2I2Y4J6 A0A2I2Y4J6 INTS12 PTHR13415:SF2 NUCLEAR FACTOR-RELATED INTEGRATOR COMPLEX SUBUNIT 12 snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;integrator complex#GO:0032039;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000004884.3|UniProtKB=G3QQC3 G3QQC3 CA5B PTHR18952:SF25 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 5B, MITOCHONDRIAL catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012794.3|UniProtKB=G3RAK6 G3RAK6 TRAF5 PTHR10131:SF83 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 5 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000034842.2|UniProtKB=G3SKQ7 G3SKQ7 COL21A1 PTHR24020:SF90 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXI) CHAIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000040134.1|UniProtKB=A0A2I2YTI2 A0A2I2YTI2 PTHR11699:SF207 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER B1, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 aldehyde catabolic process#GO:0046185;catabolic process#GO:0009056;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000009791.3|UniProtKB=G3R2V3 G3R2V3 RENBP PTHR15108:SF0 N-ACYLGLUCOSAMINE-2-EPIMERASE N-ACYLGLUCOSAMINE 2-EPIMERASE racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853 epimerase/racemase#PC00096 GORGO|Ensembl=ENSGGOG00000024870.2|UniProtKB=G3S4U3 G3S4U3 NRG1 PTHR11100:SF7 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-1, MEMBRANE-BOUND ISOFORM protein kinase regulator activity#GO:0019887;signaling receptor activator activity#GO:0030546;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase activator activity#GO:0030295;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase activator activity#GO:0019209 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;intracellular signal transduction#GO:0035556;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to stimulus#GO:0050896;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;signaling#GO:0023052;peripheral nervous system development#GO:0007422;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;brain development#GO:0007420;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;head development#GO:0060322;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 EGF receptor signaling pathway#P00018>EGF#P00549 GORGO|Ensembl=ENSGGOG00000026516.2|UniProtKB=G3SCA3 G3SCA3 VPS45 PTHR11679:SF3 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000005757.3|UniProtKB=G3QSJ9 G3QSJ9 LOC101132751 PTHR31735:SF2 VACUOLAR MEMBRANE PROTEIN YPL162C STORE-OPERATED CALCIUM ENTRY REGULATOR STIMATE channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 cytoplasm#GO:0005737;endomembrane system#GO:0012505;cortical endoplasmic reticulum#GO:0032541;cell periphery#GO:0071944;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016997.3|UniProtKB=G3RLE3 G3RLE3 TP53I13 PTHR34179:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000040263.1|UniProtKB=A0A2I2YIQ6 A0A2I2YIQ6 RUNX1 PTHR11950:SF40 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;chondrocyte differentiation#GO:0002062;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;hemopoiesis#GO:0030097;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;connective tissue development#GO:0061448;regulation of cellular process#GO:0050794;ossification#GO:0001503;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cartilage development#GO:0051216;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;cellular process#GO:0009987;nervous system development#GO:0007399;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;skeletal system development#GO:0001501 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;Runt transcription factor#PC00254 GORGO|Ensembl=ENSGGOG00000011424.3|UniProtKB=G3R713 G3R713 CDCA4 PTHR16277:SF6 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 4 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000016806.3|UniProtKB=G3RKW1 G3RKW1 UCN3 PTHR17575:SF1 UROCORTIN-2 AND 3 UROCORTIN-3 protein binding#GO:0005515;neuropeptide receptor binding#GO:0071855;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;response to nutrient levels#GO:0031667;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to nutrient levels#GO:0031669 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000016468.3|UniProtKB=G3RK08 G3RK08 VPREB1 PTHR23267:SF11 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN IOTA CHAIN immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000012235.4|UniProtKB=G3R957 G3R957 SLC35F3 PTHR19346:SF3 SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN SOLUTE CARRIER FAMILY 35 MEMBER F3 nitrogen compound transport#GO:0071705;transport#GO:0006810;vitamin transport#GO:0051180;establishment of localization#GO:0051234;localization#GO:0051179 GORGO|Ensembl=ENSGGOG00000007012.3|UniProtKB=A0A2I2ZSD8 A0A2I2ZSD8 PTHR23226:SF313 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 93 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016880.3|UniProtKB=G3RL33 G3RL33 GRPR PTHR45695:SF7 LEUCOKININ RECEPTOR-RELATED GASTRIN-RELEASING PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007984.3|UniProtKB=G3RUY0 G3RUY0 PTHR16186:SF12 SIGNAL-TRANSDUCING ADAPTOR PROTEIN-RELATED F379 RETINA SPECIFIC PROTEIN signaling adaptor activity#GO:0035591;protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;molecular adaptor activity#GO:0060090 positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of immune response#GO:0050776;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;signaling#GO:0023052;regulation of B cell receptor signaling pathway#GO:0050855;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003299.3|UniProtKB=G3SK59 G3SK59 GRIN2C PTHR18966:SF361 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2C transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310 response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051;nervous system process#GO:0050877;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;chemical synaptic transmission, postsynaptic#GO:0099565;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of postsynaptic membrane potential#GO:0060078;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;positive regulation of cellular process#GO:0048522;system process#GO:0003008;regulation of synaptic plasticity#GO:0048167 postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NR2C#P01006;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039 GORGO|Ensembl=ENSGGOG00000005985.3|UniProtKB=G3RRT9 G3RRT9 YJEFN3 PTHR13232:SF12 NAD(P)H-HYDRATE EPIMERASE YJEF N-TERMINAL DOMAIN-CONTAINING PROTEIN 3 racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000004314.3|UniProtKB=G3RN40 G3RN40 LOC101124577 PTHR23239:SF362 INTERMEDIATE FILAMENT IF ROD DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198 intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;organelle organization#GO:0006996;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;developmental process#GO:0032502;epidermis development#GO:0008544 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000006644.3|UniProtKB=G3QUU8 G3QUU8 KIAA0319 PTHR46182:SF1 FI19480P1 DYSLEXIA-ASSOCIATED PROTEIN KIAA0319 generation of neurons#GO:0048699;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;neurogenesis#GO:0022008;system development#GO:0048731;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular process#GO:0009987;nervous system development#GO:0007399;cell motility#GO:0048870;multicellular organismal process#GO:0032501;cell migration#GO:0016477;cell differentiation#GO:0030154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000014595.3|UniProtKB=G3RF73 G3RF73 DNAJC5B PTHR44027:SF6 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5B chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000013618.4|UniProtKB=A0A2I2Z6P5 A0A2I2Z6P5 FOXJ3 PTHR46078:SF3 FORKHEAD BOX PROTEIN J2 FAMILY MEMBER FORKHEAD BOX PROTEIN J3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000000928.3|UniProtKB=G3S964 G3S964 PAH PTHR11473:SF44 AROMATIC AMINO ACID HYDROXYLASE PHENYLALANINE-4-HYDROXYLASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid biosynthetic process#GO:0046394;aromatic amino acid biosynthetic process#GO:0009073;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002125.3|UniProtKB=G3QI90 G3QI90 LIN9 PTHR21689:SF2 LIN-9 PROTEIN LIN-9 HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000005300.3|UniProtKB=G3QRE2 G3QRE2 DLX2 PTHR24327:SF23 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;skeletal system development#GO:0001501;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000027119.2|UniProtKB=A0A2I2Y5G6 A0A2I2Y5G6 PTHR11431:SF117 FERRITIN FERRITIN transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;iron ion transport#GO:0006826;transport#GO:0006810;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000000036.3|UniProtKB=G3QCT7 G3QCT7 EIF3A PTHR14005:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;cytosol#GO:0005829 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000016532.3|UniProtKB=G3RK67 G3RK67 CHRNA9 PTHR18945:SF489 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 transmembrane transport#GO:0055085;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;transport#GO:0006810;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987 cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 GORGO|Ensembl=ENSGGOG00000022498.2|UniProtKB=G3S056 G3S056 TNFAIP6 PTHR46908:SF10 CUBILIN-LIKE PROTEIN TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN regulation of response to stress#GO:0080134;regulation of inflammatory response#GO:0050727;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;negative regulation of defense response#GO:0031348;negative regulation of response to stimulus#GO:0048585;negative regulation of inflammatory response#GO:0050728;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000012340.3|UniProtKB=G3R9G7 G3R9G7 CDS2 PTHR13773:SF4 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;lipid droplet organization#GO:0034389;organelle assembly#GO:0070925;lipid biosynthetic process#GO:0008610;cellular component assembly#GO:0022607;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid storage#GO:0019915;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000016558.3|UniProtKB=G3RK90 G3RK90 TAS2R40 PTHR11394:SF47 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 40 transmembrane signaling receptor activity#GO:0004888;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038 nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of taste#GO:0050909;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000036122.1|UniProtKB=G3S3A7 G3S3A7 GK3 PTHR10196:SF95 SUGAR KINASE GLYCEROL KINASE 3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;carbohydrate metabolic process#GO:0005975;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;alcohol metabolic process#GO:0006066;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739 carbohydrate kinase#PC00065;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000027818.2|UniProtKB=G3RSY9 G3RSY9 ELP4 PTHR12896:SF1 PAX6 NEIGHBOR PROTEIN PAXNEB ELONGATOR COMPLEX PROTEIN 4 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;elongator holoenzyme complex#GO:0033588;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000005935.3|UniProtKB=G3QT07 G3QT07 PTHR15583:SF10 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR E-LIKE PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;cell communication#GO:0007154;positive regulation of metabolic process#GO:0009893 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000028342.2|UniProtKB=A0A2I2ZVQ4 A0A2I2ZVQ4 RAB6B PTHR24073:SF343 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6B pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;protein localization to membrane#GO:0072657;intra-Golgi vesicle-mediated transport#GO:0006891;protein localization to organelle#GO:0033365;cytosolic transport#GO:0016482;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000023452.2|UniProtKB=G3RM70 G3RM70 CDH22 PTHR24027:SF311 CADHERIN-23 CADHERIN-22 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell migration#GO:0016477;cellular component assembly#GO:0022607;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000002013.3|UniProtKB=G3QHZ5 G3QHZ5 PLSCR3 PTHR23248:SF37 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 3 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;intramembrane lipid carrier activity#GO:0140303 phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;organophosphate ester transport#GO:0015748;cell death#GO:0008219;regulation of organelle organization#GO:0033043;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;cellular component organization#GO:0016043;programmed cell death#GO:0012501;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;regulation of release of cytochrome c from mitochondria#GO:0090199;lipid localization#GO:0010876 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001180.3|UniProtKB=A0A2I2YI16 A0A2I2YI16 FAR1 PTHR11011:SF119 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE 1 oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777 GORGO|Ensembl=ENSGGOG00000022660.2|UniProtKB=G3S924 G3S924 ENAH PTHR11202:SF1 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER PROTEIN ENABLED HOMOLOG binding#GO:0005488;protein binding#GO:0005515 cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;actin polymerization or depolymerization#GO:0008154;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 cell junction#GO:0030054;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 Axon guidance mediated by Slit/Robo#P00008>Mena#P00345;Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516;Axon guidance mediated by netrin#P00009>Ena#P00361 GORGO|Ensembl=ENSGGOG00000016474.3|UniProtKB=G3RSV7 G3RSV7 RPS6KA6 PTHR24351:SF98 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-6 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 DNA damage response#GO:0006974;biological regulation#GO:0065007;TOR signaling#GO:0031929;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;TORC1 signaling#GO:0038202;intracellular signal transduction#GO:0035556;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Ras Pathway#P04393>p90RSK#P04541;Interleukin signaling pathway#P00036>p90RSK#P00964 GORGO|Ensembl=ENSGGOG00000000112.3|UniProtKB=G3QD10 G3QD10 DYNC1H1 PTHR45703:SF41 DYNEIN HEAVY CHAIN CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000005579.3|UniProtKB=G3QS38 G3QS38 HRH4 PTHR24248:SF148 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR HISTAMINE H3 RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000025313.2|UniProtKB=G3RYG5 G3RYG5 ZNF169 PTHR23226:SF403 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 169 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000025416.2|UniProtKB=G3RX53 G3RX53 PTHR20981:SF8 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000038649.1|UniProtKB=A0A2I2YZV3 A0A2I2YZV3 PTHR23158:SF55 MELANOMA INHIBITORY ACTIVITY-RELATED MIA SH3 DOMAIN ER EXPORT FACTOR 2 export from cell#GO:0140352;protein localization to extracellular region#GO:0071692;secretion by cell#GO:0032940;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;protein secretion#GO:0009306;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;organelle membrane#GO:0031090 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000010407.3|UniProtKB=A0A2I2YV35 A0A2I2YV35 IFIT2 PTHR10271:SF4 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to cytokine#GO:0034097;response to chemical#GO:0042221;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to virus#GO:0009615;response to peptide#GO:1901652;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;cellular response to cytokine stimulus#GO:0071345;antiviral innate immune response#GO:0140374 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000004019.3|UniProtKB=G3S0G2 G3S0G2 CFTR PTHR24223:SF19 ATP-BINDING CASSETTE SUB-FAMILY C CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR gated channel activity#GO:0022836;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;polypeptide conformation or assembly isomerase activity#GO:0120544;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transmembrane transporter activity#GO:0022857;macromolecular conformation isomerase activity#GO:0120543;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;catalytic activity#GO:0003824;isomerase activity#GO:0016853 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;water transport#GO:0006833;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;fluid transport#GO:0042044;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;basal part of cell#GO:0045178;cytosol#GO:0005829;basolateral plasma membrane#GO:0016323;apical plasma membrane#GO:0016324;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;apical part of cell#GO:0045177 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000038254.1|UniProtKB=A0A2I2Z5K6 A0A2I2Z5K6 PTHR11571:SF247 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 1 glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000044095.1|UniProtKB=G3QKA8 G3QKA8 IL11RA PTHR11943:SF1 GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 nucleotidyltransferase#PC00174 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992;Fructose galactose metabolism#P02744>Hexose 1-P uridyltransferase#P02964 GORGO|Ensembl=ENSGGOG00000014160.3|UniProtKB=G3S601 G3S601 RRM1 PTHR11573:SF6 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;ATP binding#GO:0005524;small molecule binding#GO:0036094;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;metabolic process#GO:0008152;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cytosol#GO:0005829;oxidoreductase complex#GO:1990204 reductase#PC00198;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo purine biosynthesis#P02738>GDP reductase#P02909;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921 GORGO|Ensembl=ENSGGOG00000004994.3|UniProtKB=G3QQM6 G3QQM6 SRRD PTHR28626:SF3 SRR1-LIKE PROTEIN SRR1-LIKE PROTEIN intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000001759.3|UniProtKB=G3QHA8 G3QHA8 PGBD1 PTHR47055:SF1 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565 GORGO|Ensembl=ENSGGOG00000034941.2|UniProtKB=G3SKV1 G3SKV1 GALNT9 PTHR11675:SF28 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 9 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000016410.3|UniProtKB=G3RJW6 G3RJW6 APBA1 PTHR12345:SF14 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 1 binding#GO:0005488;peptide binding#GO:0042277 biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;cellular process#GO:0009987;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell junction#GO:0030054;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093;Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084 GORGO|Ensembl=ENSGGOG00000004104.3|UniProtKB=G3SIB3 G3SIB3 PTHR12555:SF20 UBIQUITIN FUSION DEGRADATON PROTEIN 1 UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1 protein binding#GO:0005515;modification-dependent protein binding#GO:0140030;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593 response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000009164.3|UniProtKB=A0A2I2YZI2 A0A2I2YZI2 LOC101130923 PTHR13936:SF14 PROFILIN PROFILIN-1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 GORGO|Ensembl=ENSGGOG00000026240.2|UniProtKB=A0A2I2Y4B4 A0A2I2Y4B4 LOC101124424 PTHR31601:SF2 28S RIBOSOMAL PROTEIN S36, MITOCHONDRIAL ALPHA-KETOGLUTARATE DEHYDROGENASE COMPONENT 4 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987 oxidoreductase complex#GO:1990204;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000040339.1|UniProtKB=A0A2I2YKT9 A0A2I2YKT9 PRSS46P PTHR24256:SF205 TRYPTASE-RELATED SERINE PROTEASE 46 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000010487.3|UniProtKB=G3R4M4 G3R4M4 MAK16 PTHR23405:SF4 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED PROTEIN MAK16 HOMOLOG rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687 GORGO|Ensembl=ENSGGOG00000003569.3|UniProtKB=G3QLY4 G3QLY4 TMPRSS7 PTHR24253:SF196 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 7 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000006418.3|UniProtKB=A0A2I2Z5G2 A0A2I2Z5G2 NR4A1 PTHR24085:SF1 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4IMMUNITYGROUP A MEMBER 1 transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulatory region nucleic acid binding#GO:0001067;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837 response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169 CCKR signaling map#P06959>NR4A1#G07289;Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#P06713;Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#G06679;Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#G06893;CCKR signaling map#P06959>NR4A1#G06995 GORGO|Ensembl=ENSGGOG00000002925.3|UniProtKB=A0A2I2Y2X6 A0A2I2Y2X6 ATXN7L1 PTHR15117:SF9 ATAXIN 7 RELATED ATAXIN-7-LIKE PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 GORGO|Ensembl=ENSGGOG00000024425.2|UniProtKB=A0A2I2YKJ1 A0A2I2YKJ1 TMEM273 PTHR37857:SF1 TRANSMEMBRANE PROTEIN 273 TRANSMEMBRANE PROTEIN 273 GORGO|Ensembl=ENSGGOG00000003491.3|UniProtKB=G3QLR5 G3QLR5 TMEM30A PTHR10926:SF17 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50A enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000004864.3|UniProtKB=G3QQA2 G3QQA2 PLSCR2 PTHR23248:SF29 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 2 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;intramembrane lipid carrier activity#GO:0140303 plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cellular component organization or biogenesis#GO:0071840;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;endomembrane system organization#GO:0010256;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;localization#GO:0051179;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;organophosphate ester transport#GO:0015748;regulation of immune system process#GO:0002682;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;regulation of response to biotic stimulus#GO:0002831;programmed cell death#GO:0012501;cell death#GO:0008219;regulation of innate immune response#GO:0045088;establishment of localization#GO:0051234;positive regulation of response to biotic stimulus#GO:0002833;regulation of membrane lipid distribution#GO:0097035;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;transport#GO:0006810;lipid transport#GO:0006869;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036;positive regulation of innate immune response#GO:0045089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000027798.2|UniProtKB=A0A2I2YPM1 A0A2I2YPM1 PLSCR5 PTHR23248:SF25 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE FAMILY MEMBER 5 phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303 regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023315.2|UniProtKB=G3RQE7 G3RQE7 LOC109025909 PTHR11961:SF15 CYTOCHROME C CYTOCHROME C, SOMATIC electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;generation of precursor metabolites and energy#GO:0006091;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ATP synthesis#P02721>Cyt C#P02798;Apoptosis signaling pathway#P00006>Cytochrome C#P00322 GORGO|Ensembl=ENSGGOG00000042433.1|UniProtKB=G3RPH6 G3RPH6 PTHR43128:SF18 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005865.3|UniProtKB=A0A2I2YY44 A0A2I2YY44 LOC101148899 PTHR10510:SF17 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A2, MITOCHONDRIAL protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane#GO:0016020;respiratory chain complex#GO:0098803;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000024959.2|UniProtKB=G3S822 G3S822 CSTA PTHR11414:SF20 CYSTATIN FAMILY MEMBER CYSTATIN-A molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000010805.3|UniProtKB=G3R5F8 G3R5F8 GHDC PTHR31901:SF9 GH3 DOMAIN-CONTAINING PROTEIN GH3 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000002074.3|UniProtKB=G3RPE8 G3RPE8 ETV7 PTHR11849:SF77 ETS TRANSCRIPTION FACTOR ETV7 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000007280.3|UniProtKB=A0A2I2YM56 A0A2I2YM56 KCNIP1 PTHR23055:SF82 CALCIUM BINDING PROTEINS A-TYPE POTASSIUM CHANNEL MODULATORY PROTEIN KCNIP1 ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;calcium ion binding#GO:0005509;potassium channel regulator activity#GO:0015459;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;channel regulator activity#GO:0016247;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515 regulation of transmembrane transport#GO:0034762;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000013638.3|UniProtKB=G3RCS5 G3RCS5 B3GALNT2 PTHR11214:SF219 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 2 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000002245.3|UniProtKB=G3QIJ9 G3QIJ9 LGI1 PTHR24367:SF17 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH GLIOMA-INACTIVATED PROTEIN 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000024948.2|UniProtKB=G3SFX6 G3SFX6 LOC101138753 PTHR48018:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5I1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008442.3|UniProtKB=A0A2I2Z1Y1 A0A2I2Z1Y1 SNAP47 PTHR19305:SF1 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 47 SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905;protein binding#GO:0005515;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;binding#GO:0005488 vesicle fusion#GO:0006906;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;synaptic vesicle membrane organization#GO:0048499;membrane fusion#GO:0061025;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;signaling#GO:0023052;export from cell#GO:0140352;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;secretion by cell#GO:0032940;cellular localization#GO:0051641;organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;vesicle fusion to plasma membrane#GO:0099500 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013469.3|UniProtKB=G3SJN5 G3SJN5 KIF1A PTHR24115:SF361 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1A polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774 vesicle-mediated transport#GO:0016192;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;cytosolic transport#GO:0016482;localization#GO:0051179;cellular localization#GO:0051641;axonal transport#GO:0098930;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;retrograde axonal transport#GO:0008090 axon#GO:0030424;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000004265.3|UniProtKB=G3QNS4 G3QNS4 ABCC4 PTHR24223:SF357 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 4 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000036836.1|UniProtKB=A0A2I2YLT4 A0A2I2YLT4 CLEC10A PTHR22802:SF416 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 10 MEMBER A binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005194.3|UniProtKB=G3SAG4 G3SAG4 NCR1 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN-RELATED signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000023912.2|UniProtKB=G3RW11 G3RW11 AMDHD2 PTHR11113:SF14 N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE deacetylase activity#GO:0019213;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;deacylase activity#GO:0160215 amino sugar catabolic process#GO:0046348;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 metabolite interconversion enzyme#PC00262;deacetylase#PC00087 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 GORGO|Ensembl=ENSGGOG00000007620.3|UniProtKB=G3QXB6 G3QXB6 PTHR14491:SF3 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHB GORGO|Ensembl=ENSGGOG00000004437.3|UniProtKB=G3RVN4 G3RVN4 HENMT1 PTHR21404:SF3 HEN1 SMALL RNA 2'-O-METHYLTRANSFERASE GORGO|Ensembl=ENSGGOG00000016517.3|UniProtKB=A0A2I2YIK4 A0A2I2YIK4 TBRG4 PTHR21228:SF59 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 4 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;regulation of RNA stability#GO:0043487;mitochondrial RNA metabolic process#GO:0000959;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000040376.1|UniProtKB=A0A2I2YMC0 A0A2I2YMC0 PTGES PTHR10689:SF9 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 PROSTAGLANDIN E SYNTHASE catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 oxoacid metabolic process#GO:0043436;prostaglandin metabolic process#GO:0006693;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;icosanoid metabolic process#GO:0006690;lipid biosynthetic process#GO:0008610;unsaturated fatty acid biosynthetic process#GO:0006636;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000036370.1|UniProtKB=G3R382 G3R382 PTHR24381:SF303 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 705A-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016328.3|UniProtKB=G3RJN6 G3RJN6 CAP2 PTHR10652:SF2 ADENYLYL CYCLASE-ASSOCIATED PROTEIN ADENYLYL CYCLASE-ASSOCIATED PROTEIN 2 protein binding#GO:0005515;enzyme binding#GO:0019899;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 cell morphogenesis#GO:0000902;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;developmental process#GO:0032502;actin filament-based process#GO:0030029 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000040855.1|UniProtKB=A0A2I2Z432 A0A2I2Z432 LOC101129504 PTHR10652:SF20 ADENYLYL CYCLASE-ASSOCIATED PROTEIN C-CAP_COFACTOR C-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;enzyme binding#GO:0019899 actin filament-based process#GO:0030029;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;actin cytoskeleton organization#GO:0030036;cell morphogenesis#GO:0000902;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000004428.3|UniProtKB=G3QP58 G3QP58 PTHR15821:SF0 PROTEIN MN1 TRANSCRIPTIONAL ACTIVATOR MN1 GORGO|Ensembl=ENSGGOG00000002462.3|UniProtKB=G3QJ42 G3QJ42 OTUD4 PTHR12419:SF9 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 4 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;negative regulation of cytokine-mediated signaling pathway#GO:0001960;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of response to cytokine stimulus#GO:0060759;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of response to cytokine stimulus#GO:0060761;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000021957.2|UniProtKB=G3SCS5 G3SCS5 PRKAB2 PTHR10343:SF92 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 GORGO|Ensembl=ENSGGOG00000009942.3|UniProtKB=G3R391 G3R391 HMMR PTHR18956:SF6 HYALURONAN MEDIATED MOTILITY RECEPTOR HYALURONAN MEDIATED MOTILITY RECEPTOR GORGO|Ensembl=ENSGGOG00000013222.3|UniProtKB=G3RBN7 G3RBN7 DNAJC14 PTHR44665:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 14 DNAJ HOMOLOG SUBFAMILY C MEMBER 14 G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000013086.3|UniProtKB=G3SG88 G3SG88 MECOM PTHR24393:SF69 ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE MECOM RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000012904.3|UniProtKB=G3RAV7 G3RAV7 MZF1 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000043689.1|UniProtKB=A0A2I2Y9H7 A0A2I2Y9H7 SPAG16 PTHR14604:SF8 WD40 REPEAT PF20 SPERM-ASSOCIATED ANTIGEN 16 PROTEIN cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578 organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axonemal central apparatus#GO:1990716;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000003231.3|UniProtKB=G3QL32 G3QL32 NKAPD1 PTHR46940:SF1 NKAP DOMAIN-CONTAINING 1 NKAP DOMAIN CONTAINING 1 GORGO|Ensembl=ENSGGOG00000009877.3|UniProtKB=G3R332 G3R332 AQP1 PTHR19139:SF161 AQUAPORIN TRANSPORTER AQUAPORIN-1 water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;carbohydrate transmembrane transporter activity#GO:0015144 response to stress#GO:0006950;renal system process#GO:0003014;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;transport#GO:0006810;chemical homeostasis#GO:0048878;response to osmotic stress#GO:0006970;establishment of localization#GO:0051234;water transport#GO:0006833;multicellular organismal-level homeostasis#GO:0048871;system process#GO:0003008;response to abiotic stimulus#GO:0009628;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;hyperosmotic response#GO:0006972;homeostatic process#GO:0042592;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological quality#GO:0065008;fluid transport#GO:0042044 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013173.3|UniProtKB=G3RBJ1 G3RBJ1 ZNF157 PTHR24377:SF34 IP01015P-RELATED ZINC FINGER PROTEIN 157 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016768.3|UniProtKB=G3RKT5 G3RKT5 ANKRD6 PTHR24203:SF84 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 6 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;establishment or maintenance of cell polarity#GO:0007163;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cellular process#GO:0009987;regulation of biological process#GO:0050789 Wnt signaling pathway#P00057>Diversin#P01466 GORGO|Ensembl=ENSGGOG00000038916.1|UniProtKB=A0A2I2Z9T9 A0A2I2Z9T9 TPM2 PTHR19269:SF46 TROPOMYOSIN TROPOMYOSIN BETA CHAIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;muscle contraction#GO:0006936;actin filament-based process#GO:0030029 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000004787.3|UniProtKB=A0A2I2Y9W7 A0A2I2Y9W7 OSBPL9 PTHR10972:SF200 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9 lipid binding#GO:0008289;steroid binding#GO:0005496;sterol binding#GO:0032934;binding#GO:0005488 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000006110.3|UniProtKB=A0A2I2Z2R9 A0A2I2Z2R9 ZNF711 PTHR24409:SF315 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 711 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002152.3|UniProtKB=G3QIB5 G3QIB5 PSMC6 PTHR23073:SF179 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 10B ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853 proteasomal protein catabolic process#GO:0010498;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular component biogenesis#GO:0044087;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription initiation#GO:2000142;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;ERAD pathway#GO:0036503;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;response to endoplasmic reticulum stress#GO:0034976 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 protease#PC00190 GORGO|Ensembl=ENSGGOG00000014588.3|UniProtKB=G3RF72 G3RF72 ABTB2 PTHR46071:SF3 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 2 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016523.3|UniProtKB=G3RK87 G3RK87 COL3A1 PTHR24023:SF604 COLLAGEN ALPHA COLLAGEN ALPHA-1(III) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure organization#GO:0045229;system development#GO:0048731;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;skeletal system development#GO:0001501;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;skin development#GO:0043588;multicellular organismal process#GO:0032501;cellular process#GO:0009987;skeletal system morphogenesis#GO:0048705 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000016026.3|UniProtKB=G3RIW2 G3RIW2 HSDL1 PTHR44889:SF1 INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000004675.3|UniProtKB=G3QPT1 G3QPT1 RABGGTB PTHR11774:SF11 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000000987.3|UniProtKB=A0A2I2Y533 A0A2I2Y533 CRTC1 PTHR13589:SF14 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription coactivator activity#GO:0003713 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 Gonadotropin-releasing hormone receptor pathway#P06664>TORC1#P06788 GORGO|Ensembl=ENSGGOG00000003643.3|UniProtKB=G3QM57 G3QM57 CD48 PTHR12080:SF134 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CD48 ANTIGEN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 leukocyte activation#GO:0045321;T cell activation#GO:0042110;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;immune system process#GO:0002376;cell activation#GO:0001775;cell communication#GO:0007154;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000008810.3|UniProtKB=A0A2I2ZTN4 A0A2I2ZTN4 PLS3 PTHR19961:SF32 FIMBRIN/PLASTIN PLASTIN-3 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;actin binding#GO:0003779;actin filament binding#GO:0051015;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;actin filament bundle assembly#GO:0051017;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 actin filament#GO:0005884;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000004689.3|UniProtKB=G3QPU2 G3QPU2 NOP9 PTHR13102:SF0 NUCLEOLAR PROTEIN 9 NUCLEOLAR PROTEIN 9 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;organelle localization#GO:0051640;nuclear transport#GO:0051169;nuclear export#GO:0051168;rRNA processing#GO:0006364;localization#GO:0051179;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transport#GO:0006810;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;establishment of organelle localization#GO:0051656;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472 organelle lumen#GO:0043233;90S preribosome#GO:0030686;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000023016.2|UniProtKB=A0A2I2Y5Y0 A0A2I2Y5Y0 PTHR43195:SF3 TRANSKETOLASE TRANSKETOLASE transketolase activity#GO:0004802;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;transferase activity#GO:0016740;transketolase or transaldolase activity#GO:0016744 nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transketolase#PC00221;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Transketolase#P03082 GORGO|Ensembl=ENSGGOG00000028450.2|UniProtKB=G3RZD9 G3RZD9 TMEM233 PTHR14948:SF19 NG5 TRANSMEMBRANE PROTEIN 233 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037971.1|UniProtKB=G3S2U1 G3S2U1 LOC101132614 PTHR23428:SF167 HISTONE H2B HISTONE H2B TYPE 3-B antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000002145.3|UniProtKB=G3QIA8 G3QIA8 CREG1 PTHR13343:SF21 CREG1 PROTEIN PROTEIN CREG1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000023615.2|UniProtKB=G3S5Z4 G3S5Z4 CCDC166 PTHR14845:SF4 COILED-COIL DOMAIN-CONTAINING 166 COILED-COIL DOMAIN-CONTAINING PROTEIN 166 GORGO|Ensembl=ENSGGOG00000027341.2|UniProtKB=A0A2I2ZSE2 A0A2I2ZSE2 PTHR43128:SF19 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000000005.3|UniProtKB=A0A2I2ZRG3 A0A2I2ZRG3 SLC38A1 PTHR22950:SF184 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID SYMPORTER 1 neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;localization#GO:0051179;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 amino acid transporter#PC00046;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000040377.1|UniProtKB=A0A2I2YL03 A0A2I2YL03 MCRIP1 PTHR48614:SF3 AT03386P MAPK-REGULATED COREPRESSOR-INTERACTING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000008774.3|UniProtKB=G3R097 G3R097 FCGRT PTHR16675:SF3 MHC CLASS I-RELATED IGG RECEPTOR FCRN LARGE SUBUNIT P51 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000011358.3|UniProtKB=G3R6V0 G3R6V0 USP12 PTHR24006:SF647 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12 cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000005216.3|UniProtKB=G3QR75 G3QR75 DYNC1LI2 PTHR12688:SF1 DYNEIN LIGHT INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;dynein complex#GO:0030286;chromosome#GO:0005694;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000000893.3|UniProtKB=G3QF16 G3QF16 PTEN PTHR12305:SF102 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 vasculature development#GO:0001944;multicellular organism development#GO:0007275;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;system development#GO:0048731;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;anatomical structure development#GO:0048856;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;blood vessel development#GO:0001568;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein phosphatase#PC00195;protein modifying enzyme#PC00260 PI3 kinase pathway#P00048>PTEN#P01189;p53 pathway#P00059>PTEN#P01480;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway feedback loops 2#P04398>PTEN#P04658;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;p53 pathway feedback loops 2#P04398>PTEN#G04714;CCKR signaling map#P06959>PTEN#P07071;Hypoxia response via HIF activation#P00030>PTEN#P00824;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PTEN#P00849;p53 pathway#P00059>PTEN#G01579 GORGO|Ensembl=ENSGGOG00000004934.3|UniProtKB=G3SHK7 G3SHK7 RPS6KA2 PTHR24351:SF213 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-2 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;TOR signaling#GO:0031929;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;TORC1 signaling#GO:0038202;intracellular signal transduction#GO:0035556 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Ras Pathway#P04393>p90RSK#P04541 GORGO|Ensembl=ENSGGOG00000015594.3|UniProtKB=G3RHT4 G3RHT4 APOL5 PTHR14096:SF6 APOLIPOPROTEIN L APOLIPOPROTEIN L5 lipid binding#GO:0008289;binding#GO:0005488 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000024385.2|UniProtKB=G3SG14 G3SG14 ISL2 PTHR24204:SF2 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 cell fate commitment#GO:0045165;axonogenesis#GO:0007409;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;cell fate specification#GO:0001708;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;neuron fate commitment#GO:0048663;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000013874.3|UniProtKB=G3RR32 G3RR32 PTHR11738:SF197 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 2DL4 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 signaling#GO:0023052;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;signal transduction#GO:0007165;immune response-regulating signaling pathway#GO:0002764;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000007778.3|UniProtKB=G3QXQ1 G3QXQ1 KHDC3L PTHR19447:SF15 OOCYTE-EXPRESSED PROTEIN HOMOLOG-RELATED KH DOMAIN-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000028021.2|UniProtKB=A0A2I2ZMY0 A0A2I2ZMY0 ASB7 PTHR24118:SF102 POTE ANKYRIN DOMAIN ANKYRIN REPEAT AND SOCS BOX PROTEIN 7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;regulation of chromatin organization#GO:1902275;protein catabolic process#GO:0030163 intracellular anatomical structure#GO:0005622;Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005077.3|UniProtKB=G3S1T0 G3S1T0 TIMM10B PTHR13172:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 B protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 mitochondrial intermembrane space#GO:0005758;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial envelope#GO:0005740;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle lumen#GO:0043233 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004850.3|UniProtKB=G3QQ91 G3QQ91 ANKRD37 PTHR24201:SF0 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 37 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000007228.3|UniProtKB=G3QWC4 G3QWC4 RBMS3 PTHR24012:SF742 RNA BINDING PROTEIN RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000028137.2|UniProtKB=A0A2I2YH80 A0A2I2YH80 DAD1 PTHR10705:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 GORGO|Gene=HBD|UniProtKB=P61773 P61773 HBD PTHR11442:SF90 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT DELTA heme binding#GO:0020037;binding#GO:0005488;molecular carrier activity#GO:0140104;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515 anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;localization#GO:0051179;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;multicellular organismal-level homeostasis#GO:0048871;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transfer/carrier protein#PC00219;globin#PC00107 GORGO|Ensembl=ENSGGOG00000008730.3|UniProtKB=G3R058 G3R058 CD5L PTHR48071:SF8 SRCR DOMAIN-CONTAINING PROTEIN CD5 ANTIGEN-LIKE regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of immune effector process#GO:0002697;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000000378.3|UniProtKB=G3QDP7 G3QDP7 GRID2 PTHR18966:SF109 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803 biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;dendrite#GO:0030425;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;synaptic membrane#GO:0097060;transporter complex#GO:1990351;cell junction#GO:0030054;neuron projection#GO:0043005;protein-containing complex#GO:0032991;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;dendritic spine#GO:0043197;postsynapse#GO:0098794;neuron spine#GO:0044309;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009387.3|UniProtKB=A0A2I2YTX3 A0A2I2YTX3 MTMR12 PTHR10807:SF37 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 12 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;dephosphorylation#GO:0016311;lipid modification#GO:0030258 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000003122.3|UniProtKB=G3QKT6 G3QKT6 MECR PTHR43981:SF9 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000006779.3|UniProtKB=A0A2I2YWI0 A0A2I2YWI0 DDX42 PTHR24031:SF125 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX42 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000024184.2|UniProtKB=G3RS83 G3RS83 LOC101151351 PTHR24056:SF600 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 20 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015892.3|UniProtKB=G3RIJ6 G3RIJ6 TRPC5 PTHR10117:SF76 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 5 binding#GO:0005488;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;channel activity#GO:0015267;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480;metal ion transport#GO:0030001;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 GORGO|Ensembl=ENSGGOG00000015211.3|UniProtKB=G3RGT5 G3RGT5 TMEM74B PTHR16125:SF4 TRANSMEMBRANE PROTEIN 74 TRANSMEMBRANE PROTEIN 74B GORGO|Ensembl=ENSGGOG00000013657.3|UniProtKB=G3RCU1 G3RCU1 AMBN PTHR14115:SF0 AMELOBLASTIN AMELOBLASTIN signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell adhesion#GO:0007155;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000024688.2|UniProtKB=A0A2I2Y7W6 A0A2I2Y7W6 PDC PTHR46052:SF3 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;9+0 non-motile cilium#GO:0097731;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Phosducin#P00758 GORGO|Ensembl=ENSGGOG00000008685.3|UniProtKB=G3S3Y7 G3S3Y7 ECT2 PTHR16777:SF2 PROTEIN ECT2 PROTEIN ECT2 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cell cycle#GO:0007049;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic cell cycle process#GO:1903047 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;cell cortex#GO:0005938 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000015358.3|UniProtKB=A0A2I2ZP61 A0A2I2ZP61 SLC2A9 PTHR23503:SF35 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 9 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;import across plasma membrane#GO:0098739;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000002509.3|UniProtKB=G3QJ85 G3QJ85 FAM181B PTHR33766:SF2 PROTEIN FAM181B PROTEIN FAM181B GORGO|Ensembl=ENSGGOG00000007776.3|UniProtKB=G3S851 G3S851 CD40 PTHR46875:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 regulation of immune response#GO:0050776;cell activation#GO:0001775;immune system process#GO:0002376;cell communication#GO:0007154;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;B cell activation#GO:0042113;signal transduction#GO:0007165;cellular process#GO:0009987;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501 external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;side of membrane#GO:0098552;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008951.3|UniProtKB=A0A2I2ZJ00 A0A2I2ZJ00 MAPK3 PTHR24055:SF393 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 3 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell surface receptor signaling pathway#GO:0007166 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>MAPK3#P07119;CCKR signaling map#P06959>MAPK1/3#P07228;Ras Pathway#P04393>ERK#P04542;T cell activation#P00053>ERK#P01300;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Endothelin signaling pathway#P00019>ERK#P00566;Apoptosis signaling pathway#P00006>MAPK#P00269;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Parkinson disease#P00049>ERK#P01211;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;VEGF signaling pathway#P00056>Erk#P01407;Gonadotropin-releasing hormone receptor pathway#P06664>ERK1/2#P06786;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Toll receptor signaling pathway#P00054>ERK1#P01358;Angiogenesis#P00005>Erk#P00203;FGF signaling pathway#P00021>ERK1-2#P00627;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;VEGF signaling pathway#P00056>MEK#P01402;B cell activation#P00010>ERK#P00371;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MAPK#P05937;Integrin signalling pathway#P00034>ERK#P00907;Interleukin signaling pathway#P00036>ERK#P00965;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835 GORGO|Ensembl=ENSGGOG00000002006.3|UniProtKB=G3SHD7 G3SHD7 ATP2A3 PTHR42861:SF6 CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 3 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000038116.1|UniProtKB=A0A2I2YU60 A0A2I2YU60 RIPPLY3 PTHR16770:SF4 PROTEIN RIPPLY-LIKE PROTEIN RIPPLY3 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of macromolecule biosynthetic process#GO:0010558;embryonic pattern specification#GO:0009880;embryo development#GO:0009790;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000002569.3|UniProtKB=A1YF08 A1YF08 PDX1 PTHR45664:SF12 PROTEIN ZERKNUELLT 1-RELATED PANCREAS_DUODENUM HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;pancreas development#GO:0031016;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000005044.3|UniProtKB=G3SF47 G3SF47 PSMD3 PTHR10758:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 proteasome complex#GO:0000502;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protease#PC00190;protein modifying enzyme#PC00260 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000005857.3|UniProtKB=G3QST2 G3QST2 GJD4 PTHR11984:SF3 CONNEXIN GAP JUNCTION DELTA-4 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 regulation of biological process#GO:0050789;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;cell communication#GO:0007154 membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell junction#GO:0030054;anchoring junction#GO:0070161 gap junction#PC00105;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000006879.3|UniProtKB=A0A2I2ZWX0 A0A2I2ZWX0 NFATC1 PTHR12533:SF5 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;calcineurin-mediated signaling#GO:0097720;calcineurin-NFAT signaling cascade#GO:0033173;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;calcium-mediated signaling#GO:0019722;regulation of biosynthetic process#GO:0009889;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of transcription by RNA polymerase II#GO:0045944 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 immunoglobulin fold transcription factor#PC00251;gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252 Wnt signaling pathway#P00057>NFAT#P01452;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367;Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851 GORGO|Ensembl=ENSGGOG00000012732.3|UniProtKB=G3RAI0 G3RAI0 SZT2 PTHR14918:SF3 KICSTOR COMPLEX PROTEIN SZT2 KICSTOR COMPLEX PROTEIN SZT2 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;system development#GO:0048731;negative regulation of cell communication#GO:0010648;anatomical structure development#GO:0048856;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;central nervous system development#GO:0007417;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;developmental process#GO:0032502;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;multicellular organism development#GO:0007275;regulation of TOR signaling#GO:0032006;response to nutrient levels#GO:0031667;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;nervous system development#GO:0007399;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585 lytic vacuole membrane#GO:0098852;peroxisome#GO:0005777;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;lysosomal membrane#GO:0005765;microbody#GO:0042579;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 GORGO|Ensembl=ENSGGOG00000041185.1|UniProtKB=A0A2I2ZE95 A0A2I2ZE95 PTHR45832:SF21 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE Ras Pathway#P04393>PAK#P04553;Angiogenesis#P00005>PAK#P00249;T cell activation#P00053>PAK#P01319;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517 GORGO|Gene=COI|UniProtKB=Q9T9Y8 Q9T9Y8 COI PTHR10422:SF18 CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 1 proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176;oxidase#PC00175 ATP synthesis#P02721>Cytochrome oxidase aa3#P02793 GORGO|Ensembl=ENSGGOG00000016562.3|UniProtKB=A0A2I2YJ82 A0A2I2YJ82 GNPAT PTHR12563:SF17 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000014925.3|UniProtKB=A0A2I2Y6Z2 A0A2I2Y6Z2 RILPL1 PTHR21502:SF6 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN 1 binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000042790.1|UniProtKB=A0A2I2Z4X2 A0A2I2Z4X2 PCYOX1 PTHR15944:SF3 FARNESYLCYSTEINE LYASE PRENYLCYSTEINE OXIDASE 1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metabolite interconversion enzyme#PC00262;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000022578.2|UniProtKB=G3SJ62 G3SJ62 PTHR11905:SF140 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN A DISINTEGRIN AND METALLOPEPTIDASE DOMAIN 6-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;reproductive system development#GO:0061458;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;reproductive structure development#GO:0048608;reproductive process#GO:0022414;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;animal organ development#GO:0048513;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;male sex differentiation#GO:0046661;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;multicellular organismal process#GO:0032501;gonad development#GO:0008406;sex differentiation#GO:0007548;cellular process#GO:0009987;male gonad development#GO:0008584 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000000691.3|UniProtKB=A0A2I2ZTT8 A0A2I2ZTT8 FHAD1 PTHR18853:SF7 FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000008618.3|UniProtKB=G3QZW4 G3QZW4 ABCB5 PTHR24221:SF217 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 5 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000015929.3|UniProtKB=G3RIN3 G3RIN3 PRKCA PTHR24356:SF193 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ALPHA TYPE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>PKCs#P00318;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;CCKR signaling map#P06959>PKCalpha#P07095;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PKC#P05942;PDGF signaling pathway#P00047>PKC#P01150;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs(3)#P06850;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Angiogenesis#P00005>PKC#P00219;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Endothelin signaling pathway#P00019>PKC#P00568 GORGO|Ensembl=ENSGGOG00000002339.2|UniProtKB=G3QIT6 G3QIT6 C19orf67 PTHR36292:SF1 UPF0575 PROTEIN C19ORF67 UPF0575 PROTEIN C19ORF67 GORGO|Ensembl=ENSGGOG00000005531.3|UniProtKB=G3QS00 G3QS00 TAS1R2 PTHR24061:SF517 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;sensory perception#GO:0007600 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008897.3|UniProtKB=G3R0L0 G3R0L0 GGPS1 PTHR12001:SF44 GERANYLGERANYL PYROPHOSPHATE SYNTHASE GERANYLGERANYL PYROPHOSPHATE SYNTHASE prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 isoprenoid metabolic process#GO:0006720;metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 GORGO|Ensembl=ENSGGOG00000012597.3|UniProtKB=G3RUW4 G3RUW4 LOC101139167 PTHR10183:SF329 CALPAIN CALPAIN-3 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 negative regulation of cellular process#GO:0048523;proteolysis#GO:0006508;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000014415.3|UniProtKB=G3RES5 G3RES5 C5H6orf118 PTHR34916:SF1 GI:13385330 RIKEN CDNA 1700010I14 GENE GORGO|Ensembl=ENSGGOG00000040402.1|UniProtKB=G3RJ64 G3RJ64 PTHR10701:SF23 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N ELASTIN binding#GO:0005488;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 U2 snRNP#GO:0005686;U5 snRNP#GO:0005682;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U2-type prespliceosome#GO:0071004;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000005791.3|UniProtKB=G3QSM8 G3QSM8 PTHR10153:SF38 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 1 ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;calcium-activated potassium channel activity#GO:0015269;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;binding#GO:0005488;gated channel activity#GO:0022836;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;calmodulin binding#GO:0005516;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 membrane#GO:0016020;cell body#GO:0044297;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000026080.2|UniProtKB=A0A2I2YNF1 A0A2I2YNF1 ANKRD34A PTHR24156:SF4 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34A GORGO|Ensembl=ENSGGOG00000022515.2|UniProtKB=G3SHS0 G3SHS0 ZNF30 PTHR24381:SF425 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 626 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004433.3|UniProtKB=G3QP63 G3QP63 TWSG1 PTHR12312:SF17 TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED TWISTED GASTRULATION PROTEIN HOMOLOG 1 regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of BMP signaling pathway#GO:0030510;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016156.3|UniProtKB=G3RJ79 G3RJ79 NWD2 PTHR19871:SF39 BETA TRANSDUCIN-RELATED PROTEIN NACHT AND WD REPEAT DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000012599.3|UniProtKB=G3RA34 G3RA34 AMHR2 PTHR23255:SF49 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ANTI-MUELLERIAN HORMONE TYPE-2 RECEPTOR signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transforming growth factor beta receptor activity#GO:0005024;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674 cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>MISRII#P06792 GORGO|Ensembl=ENSGGOG00000011813.3|UniProtKB=G3R822 G3R822 STOML3 PTHR10264:SF49 BAND 7 PROTEIN-RELATED STOMATIN-LIKE PROTEIN 3 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000042107.1|UniProtKB=A0A2I2Z9K7 A0A2I2Z9K7 ACTL10 PTHR11937:SF183 ACTIN ACTIN-LIKE PROTEIN 10 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000015147.3|UniProtKB=G3S644 G3S644 KLHL1 PTHR24412:SF75 KELCH PROTEIN KELCH-LIKE PROTEIN 1 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027495.2|UniProtKB=G3SEG2 G3SEG2 SAT2 PTHR10545:SF51 DIAMINE N-ACETYLTRANSFERASE THIALYSINE N-EPSILON-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 transferase#PC00220;acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000007371.3|UniProtKB=G3SK82 G3SK82 RBM19 PTHR23147:SF48 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 19-RELATED intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000037331.1|UniProtKB=A0A2I2YJJ6 A0A2I2YJJ6 PTHR10540:SF15 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED JAB1_MPN_MOV34 METALLOENZYME DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;proteasome complex#GO:0000502 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000004637.3|UniProtKB=G3QPP2 G3QPP2 APBA3 PTHR12345:SF9 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 3 binding#GO:0005488;peptide binding#GO:0042277 anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 cell junction#GO:0030054;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;dendritic spine#GO:0043197 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093;Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084 GORGO|Ensembl=ENSGGOG00000021961.2|UniProtKB=G3S0N0 G3S0N0 METTL24 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED methyltransferase#PC00155;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000016641.3|UniProtKB=G3RKH2 G3RKH2 ZNF423 PTHR24409:SF306 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 423 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010708.3|UniProtKB=G3R572 G3R572 ATP23 PTHR21711:SF0 MITOCHONDRIAL INNER MEMBRANE PROTEASE MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;mitochondrion organization#GO:0007005;biosynthetic process#GO:0009058;mitochondrial respiratory chain complex assembly#GO:0033108;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein metabolic process#GO:0019538;proteolysis#GO:0006508;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000025012.2|UniProtKB=G3SGN6 G3SGN6 PTHR11587:SF5 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;ligase#PC00142 Arginine biosynthesis#P02728>Argininosuccinate synthase#P02840 GORGO|Ensembl=ENSGGOG00000012519.3|UniProtKB=G3R9W5 G3R9W5 CD79B PTHR14334:SF2 B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN BETA CHAIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 immune system process#GO:0002376;cell development#GO:0048468;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;mononuclear cell differentiation#GO:1903131;regulation of biological process#GO:0050789;leukocyte differentiation#GO:0002521;B cell activation#GO:0042113;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;lymphocyte activation#GO:0046649;cellular process#GO:0009987;B cell receptor signaling pathway#GO:0050853;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell activation#GO:0001775;regulation of immune response#GO:0050776;lymphocyte differentiation#GO:0030098;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;developmental process#GO:0032502;hemopoiesis#GO:0030097;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 B cell activation#P00010>Ig-beta#P00377 GORGO|Ensembl=ENSGGOG00000013358.3|UniProtKB=G3RC13 G3RC13 C13H9orf78 PTHR13486:SF2 TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER SPLICING FACTOR C9ORF78 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000002664.3|UniProtKB=G3QJM6 G3QJM6 CCDC127 PTHR31958:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 GORGO|Ensembl=ENSGGOG00000000418.3|UniProtKB=A0A2I2ZTH7 A0A2I2ZTH7 ABCC5 PTHR24223:SF196 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 5 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000026560.2|UniProtKB=G3RQE0 G3RQE0 PTHR23430:SF355 HISTONE H2A HISTONE H2A.J structural molecule activity#GO:0005198 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000025311.2|UniProtKB=A0A2I2YTN3 A0A2I2YTN3 PTHR10715:SF7 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011793.3|UniProtKB=G3R802 G3R802 TRIM25 PTHR25465:SF77 B-BOX DOMAIN CONTAINING E3 UBIQUITIN_ISG15 LIGASE TRIM25 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000015280.3|UniProtKB=G3RGZ4 G3RGZ4 CD79A PTHR14334:SF1 B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN ALPHA CHAIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 antigen receptor-mediated signaling pathway#GO:0050851;lymphocyte activation#GO:0046649;positive regulation of immune system process#GO:0002684;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;immune response-activating signaling pathway#GO:0002757;B cell activation#GO:0042113;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;leukocyte differentiation#GO:0002521;mononuclear cell differentiation#GO:1903131;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;hemopoiesis#GO:0030097;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of immune response#GO:0050778;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;regulation of immune response#GO:0050776 external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;side of membrane#GO:0098552;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 B cell activation#P00010>Ig-alpha#P00399 GORGO|Ensembl=ENSGGOG00000028124.2|UniProtKB=G3RPQ6 G3RPQ6 IQCB1 PTHR15673:SF2 IQ CALMODULIN-BINDING MOTIF CONTAINING PROTEIN 1 IQ CALMODULIN-BINDING MOTIF-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025 GORGO|Gene=1C04_GORGO|UniProtKB=P30387 P30387 PTHR16675:SF294 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, C ALPHA CHAIN antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of immune system process#GO:0002684;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000024068.2|UniProtKB=A0A2I2ZE20 A0A2I2ZE20 PTHR31184:SF2 HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER HUNTINGTIN-INTERACTING PROTEIN K regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 GORGO|Ensembl=ENSGGOG00000013891.3|UniProtKB=A0A2I2YPG1 A0A2I2YPG1 YIF1B PTHR14083:SF1 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN PROTEIN YIF1B intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000004711.3|UniProtKB=G3QPV7 G3QPV7 B3GNT8 PTHR11214:SF87 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 8 transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;aminoglycan biosynthetic process#GO:0006023;biosynthetic process#GO:0009058;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000005269.3|UniProtKB=G3RT16 G3RT16 NBL1 PTHR15283:SF5 GREMLIN 1 NEUROBLASTOMA SUPPRESSOR OF TUMORIGENICITY 1 binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine binding#GO:0019955;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008894.3|UniProtKB=G3SJ24 G3SJ24 PTHR42908:SF3 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR-LIKE GTPASE 1 hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational elongation#GO:0006414;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;protein metabolic process#GO:0019538;translation#GO:0006412;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000023316.2|UniProtKB=G3RXG1 G3RXG1 CHMP4BP1 PTHR22761:SF41 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4B-LIKE PROTEIN CHMP4BP1-RELATED localization#GO:0051179;cellular localization#GO:0051641;membrane assembly#GO:0071709;cellular component organization#GO:0016043;late endosome to vacuole transport#GO:0045324;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;nucleus organization#GO:0006997;establishment of localization in cell#GO:0051649;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nuclear membrane organization#GO:0071763;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;vesicle#GO:0031982;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;plasma membrane#GO:0005886;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic side of membrane#GO:0098562 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011187.2|UniProtKB=G3RXD0 G3RXD0 ACKR2 PTHR10489:SF942 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000015843.3|UniProtKB=G3RIF6 G3RIF6 FAM171A2 PTHR31626:SF3 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171A2 GORGO|Ensembl=ENSGGOG00000013124.3|UniProtKB=G3RBF1 G3RBF1 CIDEC PTHR12306:SF9 CELL DEATH ACTIVATOR CIDE LIPID TRANSFERASE CIDEC lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215 organelle fusion#GO:0048284;cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;lipid storage#GO:0019915;cellular component organization#GO:0016043;programmed cell death#GO:0012501;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;lipid droplet organization#GO:0034389 intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015428.3|UniProtKB=G3SAR2 G3SAR2 PTHR13112:SF2 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN REGULATOR OF NONSENSE TRANSCRIPTS 3A mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;RNA binding#GO:0003723;DNA binding#GO:0003677 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000016344.3|UniProtKB=G3RJP5 G3RJP5 CHRM1 PTHR24248:SF155 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>mAChR1/3#P01069 GORGO|Ensembl=ENSGGOG00000005820.3|UniProtKB=G3QSQ2 G3QSQ2 PHF23 PTHR14571:SF8 HISTONE-LYSINE N-METHYLTRANSFERASE SET-26-RELATED PHD FINGER PROTEIN 23 regulation of macroautophagy#GO:0016241;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macroautophagy#GO:0016242;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247;regulation of autophagosome assembly#GO:2000785;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of protein modification process#GO:0031399;regulation of protein ubiquitination#GO:0031396;regulation of autophagosome maturation#GO:1901096;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000039540.1|UniProtKB=A0A2I2YH30 A0A2I2YH30 ZNF729 PTHR24393:SF62 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000013301.3|UniProtKB=G3RBW2 G3RBW2 EZR PTHR23281:SF13 MERLIN/MOESIN/EZRIN/RADIXIN EZRIN cell adhesion molecule binding#GO:0050839;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of anatomical structure morphogenesis#GO:0022603 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;membraneless organelle#GO:0043228;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;filopodium#GO:0030175;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000010434.3|UniProtKB=A0A2I2ZJT4 A0A2I2ZJT4 FGD4 PTHR12673:SF98 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 4 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;filopodium assembly#GO:0046847;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000014857.3|UniProtKB=G3RSQ3 G3RSQ3 TTLL2 PTHR12241:SF118 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL2-RELATED catalytic activity#GO:0003824;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000015398.3|UniProtKB=G3RRG1 G3RRG1 LPAR6 PTHR24232:SF3 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 6 transmembrane signaling receptor activity#GO:0004888;bioactive lipid receptor activity#GO:0045125;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009009.3|UniProtKB=G3SIR9 G3SIR9 REXO1 PTHR12801:SF62 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 1 HOMOLOG nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 exoribonuclease#PC00099;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000034822.2|UniProtKB=G3SKF3 G3SKF3 RNASEH1 PTHR10642:SF35 RIBONUCLEASE H1 RIBONUCLEASE H1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 catabolic process#GO:0009056;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;RNA metabolic process#GO:0016070;mitochondrial DNA metabolic process#GO:0032042;DNA-templated DNA replication#GO:0006261;RNA catabolic process#GO:0006401;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 endoribonuclease#PC00094;RNA metabolism protein#PC00031 DNA replication#P00017>RNase H#P00538 GORGO|Ensembl=ENSGGOG00000015000.3|UniProtKB=A0A2I2Z7Y1 A0A2I2Z7Y1 SBNO1 PTHR12706:SF8 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH HOMOLOG 1 protein binding#GO:0005515;DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;histone binding#GO:0042393;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015155.3|UniProtKB=G3S8R6 G3S8R6 PTHR11489:SF17 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2-RELATED structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;translation#GO:0006412;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000040484.1|UniProtKB=A0A2I2YC13 A0A2I2YC13 SENP8 PTHR46468:SF1 SENTRIN-SPECIFIC PROTEASE 8 SENTRIN-SPECIFIC PROTEASE 8 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687 protease#PC00190 GORGO|Ensembl=ENSGGOG00000040359.1|UniProtKB=G3R0Q0 G3R0Q0 IQCE PTHR22590:SF3 MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN IQ DOMAIN-CONTAINING PROTEIN E GORGO|Ensembl=ENSGGOG00000015343.3|UniProtKB=G3RH53 G3RH53 PSPH PTHR43344:SF2 PHOSPHOSERINE PHOSPHATASE PHOSPHOSERINE PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787 proteinogenic amino acid biosynthetic process#GO:0170038;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Phosphoserine phosphatase#P03159 GORGO|Ensembl=ENSGGOG00000014891.3|UniProtKB=G3RFZ8 G3RFZ8 AZIN2 PTHR11482:SF4 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ANTIZYME INHIBITOR 2 molecular function activator activity#GO:0140677;ornithine decarboxylase activity#GO:0004586;enzyme regulator activity#GO:0030234;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;carboxy-lyase activity#GO:0016831;molecular function regulator activity#GO:0098772 regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;polyamine metabolic process#GO:0006595;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;polyamine biosynthetic process#GO:0006596;negative regulation of protein catabolic process#GO:0042177;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;amine metabolic process#GO:0009308;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;negative regulation of macromolecule metabolic process#GO:0010605 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 GORGO|Ensembl=ENSGGOG00000010612.3|UniProtKB=G3R4Y3 G3R4Y3 RAC2 PTHR24072:SF169 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 response to chemical#GO:0042221;taxis#GO:0042330;positive regulation of cellular component biogenesis#GO:0044089;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection assembly#GO:0120032;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;establishment or maintenance of cell polarity#GO:0007163;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;actin filament organization#GO:0007015;response to external stimulus#GO:0009605;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;regulation of cell migration#GO:0030334;regulation of cytoskeleton organization#GO:0051493;regulation of leukocyte migration#GO:0002685;regulation of immune system process#GO:0002682;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell motility#GO:2000145;supramolecular fiber organization#GO:0097435;regulation of cell projection assembly#GO:0060491;cortical cytoskeleton organization#GO:0030865;chemotaxis#GO:0006935;positive regulation of cell projection organization#GO:0031346;actin filament-based process#GO:0030029 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 small GTPase#PC00208;G-protein#PC00020 Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;p38 MAPK pathway#P05918>Rac#P06021;B cell activation#P00010>Rac#P00385;VEGF signaling pathway#P00056>Rac#P01421;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;Axon guidance mediated by semaphorins#P00007>Rac#P00340;Axon guidance mediated by netrin#P00009>Rac#P00366;FGF signaling pathway#P00021>Rac#P00645;Huntington disease#P00029>Rac#P00775;Integrin signalling pathway#P00034>Rac#P00927;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;T cell activation#P00053>rac#P01324;Ras Pathway#P04393>Rac#P04559;EGF receptor signaling pathway#P00018>Rac#P00564 GORGO|Ensembl=ENSGGOG00000013433.3|UniProtKB=G3S1N4 G3S1N4 GRIN2D PTHR18966:SF385 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2D voltage-gated channel activity#GO:0022832;voltage-gated monoatomic ion channel activity#GO:0005244;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;positive regulation of cellular process#GO:0048522;system process#GO:0003008;regulation of synaptic plasticity#GO:0048167;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;chemical synaptic transmission, postsynaptic#GO:0099565;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of postsynaptic membrane potential#GO:0060078;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051;nervous system process#GO:0050877 synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cell junction#GO:0030054;transporter complex#GO:1990351;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Ionotropic glutamate receptor pathway#P00037>NR2D#P01005;Huntington disease#P00029>NMDA receptor#P00778;Ionotropic glutamate receptor pathway#P00037>NR2C#P01006;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071 GORGO|Ensembl=ENSGGOG00000000009.3|UniProtKB=G3RZQ2 G3RZQ2 CACNG5 PTHR12107:SF4 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-5 SUBUNIT voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262 regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;localization#GO:0051179;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;regulation of signaling#GO:0023051;nervous system process#GO:0050877;localization within membrane#GO:0051668;positive regulation of synaptic transmission#GO:0050806;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;transmission of nerve impulse#GO:0019226;system process#GO:0003008;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072 transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>stargazin#P00998 GORGO|Ensembl=ENSGGOG00000011777.3|UniProtKB=G3R7Y4 G3R7Y4 CD1D PTHR16675:SF175 MHC CLASS I-RELATED ANTIGEN-PRESENTING GLYCOPROTEIN CD1D binding#GO:0005488;antigen binding#GO:0003823;lipid binding#GO:0008289 positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of leukocyte mediated cytotoxicity#GO:0001910;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000038894.1|UniProtKB=A0A2I2YTK2 A0A2I2YTK2 CTDSPL PTHR12210:SF43 DULLARD PROTEIN PHOSPHATASE CTD SMALL PHOSPHATASE-LIKE PROTEIN hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000016908.3|UniProtKB=G3RL62 G3RL62 POF1B PTHR22546:SF0 PREMATURE OVARIAN FAILURE, 1B PROTEIN POF1B actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component assembly#GO:0022607;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;actin filament organization#GO:0007015;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;actin cytoskeleton organization#GO:0030036;cell development#GO:0048468;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029 cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;bicellular tight junction#GO:0005923;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cell-cell junction#GO:0005911;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;tight junction#GO:0070160;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical junction complex#GO:0043296;actin filament#GO:0005884 GORGO|Ensembl=ENSGGOG00000004418.3|UniProtKB=G3QP52 G3QP52 AEBP1 PTHR11532:SF48 PROTEASE M14 CARBOXYPEPTIDASE ADIPOCYTE ENHANCER-BINDING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;sequence-specific double-stranded DNA binding#GO:1990837;catalytic activity#GO:0003824;DNA binding#GO:0003677;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;double-stranded DNA binding#GO:0003690;carboxypeptidase activity#GO:0004180;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;metallopeptidase activity#GO:0008237;transcription cis-regulatory region binding#GO:0000976;peptidase activity#GO:0008233;sequence-specific DNA binding#GO:0043565;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 GORGO|Ensembl=ENSGGOG00000006506.3|UniProtKB=G3QUG7 G3QUG7 SIPA1L3 PTHR15711:SF15 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 3 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 establishment of cell polarity#GO:0030010;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;cell differentiation#GO:0030154;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cell morphogenesis#GO:0000902;cell development#GO:0048468;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000004150.3|UniProtKB=G3QNF8 G3QNF8 ZNF416 PTHR24377:SF724 IP01015P-RELATED ZINC FINGER PROTEIN 416 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007118.3|UniProtKB=G3QW83 G3QW83 COL7A1 PTHR24023:SF1071 COLLAGEN ALPHA COLLAGEN ALPHA-1(VII) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000007473.3|UniProtKB=G3QWY8 G3QWY8 MTFR1 PTHR14215:SF1 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 1 mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001705.3|UniProtKB=G3RUJ9 G3RUJ9 BCAM PTHR11973:SF17 CELL SURFACE GLYCOPROTEIN MUC18-RELATED BASAL CELL ADHESION MOLECULE plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000010849.3|UniProtKB=G3R5J5 G3R5J5 PTHR43391:SF15 RETINOL DEHYDROGENASE-RELATED 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;steroid biosynthetic process#GO:0006694;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;hormone biosynthetic process#GO:0042446;biosynthetic process#GO:0009058;biological regulation#GO:0065007;steroid metabolic process#GO:0008202 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 GORGO|Ensembl=ENSGGOG00000014004.3|UniProtKB=G3RDP9 G3RDP9 OTULINL PTHR33662:SF1 OTU DEUBIQUITINASE WITH LINEAR LINKAGE-SPECIFICITY A-RELATED INACTIVE UBIQUITIN THIOESTERASE OTULINL cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cytoplasmic side of membrane#GO:0098562;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;side of membrane#GO:0098552;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000014385.3|UniProtKB=G3RPZ5 G3RPZ5 SRM PTHR11558:SF11 SPERMIDINE/SPERMINE SYNTHASE SPERMIDINE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000011114.3|UniProtKB=A0A2I2Y4T3 A0A2I2Y4T3 ACYP2 PTHR10029:SF20 ACYLPHOSPHATASE ACYLPHOSPHATASE-2 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010160.3|UniProtKB=G3R3T5 G3R3T5 SLC25A47 PTHR45624:SF3 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 47 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007617.3|UniProtKB=A0A2I2YRF9 A0A2I2YRF9 KCNK17 PTHR11003:SF340 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 17 gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007138.3|UniProtKB=G3QW36 G3QW36 PTHR11738:SF170 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 3-RELATED signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;response to cytokine#GO:0034097;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of immune response#GO:0050776;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000132.3|UniProtKB=G3QD27 G3QD27 DNASE1L1 PTHR11371:SF28 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1-LIKE 1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;DNA catabolic process#GO:0006308;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 endodeoxyribonuclease#PC00093 GORGO|Ensembl=ENSGGOG00000003246.3|UniProtKB=G3QL55 G3QL55 SF3B3 PTHR10644:SF1 DNA REPAIR/RNA PROCESSING CPSF FAMILY SPLICING FACTOR 3B SUBUNIT 3 binding#GO:0005488;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;RNA binding#GO:0003723 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 U2 snRNP#GO:0005686;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000001619.3|UniProtKB=G3QGX9 G3QGX9 TRIM13 PTHR24103:SF609 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM13 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;innate immune response#GO:0045087;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of macroautophagy#GO:0016241;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;defense response to other organism#GO:0098542;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;positive regulation of macroautophagy#GO:0016239;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002140.3|UniProtKB=G3QIA1 G3QIA1 ZNF510 PTHR24381:SF411 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 510 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002030.3|UniProtKB=G3QI11 G3QI11 ANKFY1 PTHR24118:SF82 POTE ANKYRIN DOMAIN ANKYRIN REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;binding#GO:0005488;small GTPase binding#GO:0031267;protein binding#GO:0005515 cytosolic transport#GO:0016482;post-Golgi vesicle-mediated transport#GO:0006892;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641;localization#GO:0051179;lysosomal transport#GO:0007041;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;retromer complex#GO:0030904;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005772.3|UniProtKB=G3S325 G3S325 LOC101142134 PTHR16675:SF256 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN H-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;peptide binding#GO:0042277;antigen binding#GO:0003823;protein binding#GO:0005515 regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000007013.3|UniProtKB=G3QVT6 G3QVT6 TMC2 PTHR23302:SF17 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 2 transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245 system process#GO:0003008;response to external stimulus#GO:0009605;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of mechanical stimulus#GO:0050982;response to stimulus#GO:0050896;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501;response to mechanical stimulus#GO:0009612;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to abiotic stimulus#GO:0009628 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000010335.3|UniProtKB=G3R497 G3R497 AVL9 PTHR31017:SF1 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009903.3|UniProtKB=G3RM34 G3RM34 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;regulation of protein stability#GO:0031647;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000015791.3|UniProtKB=G3RIA7 G3RIA7 BMP8A PTHR11848:SF119 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 8A-RELATED receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000003927.3|UniProtKB=G3RVD5 G3RVD5 PDIK1L PTHR11042:SF58 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED SERINE_THREONINE-PROTEIN KINASE PDIK1L transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000039599.1|UniProtKB=A0A2I2Y1Q3 A0A2I2Y1Q3 PTHR45699:SF1 60S ACIDIC RIBOSOMAL PROTEIN P0 LARGE RIBOSOMAL SUBUNIT PROTEIN UL10-RELATED structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011025.3|UniProtKB=G3R609 G3R609 HIPK4 PTHR24058:SF46 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 4 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000039596.1|UniProtKB=A0A2I2ZWE5 A0A2I2ZWE5 PTHR10052:SF33 60S RIBOSOMAL PROTEIN L18A 60S RIBOSOMAL PROTEIN L18A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014346.3|UniProtKB=G3REK2 G3REK2 PTHR10639:SF28 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN B protein binding#GO:0005515;binding#GO:0005488;clathrin binding#GO:0030276 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;secretory vesicle#GO:0099503;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;coated vesicle membrane#GO:0030662;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;plasma membrane#GO:0005886;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117 membrane traffic protein#PC00150;vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Huntington disease#P00029>Clathrin#P00798;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 GORGO|Ensembl=ENSGGOG00000024185.2|UniProtKB=G3S988 G3S988 LOC101129229 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000022453.2|UniProtKB=G3SDV4 G3SDV4 CCT6B PTHR11353:SF58 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ZETA-2-RELATED macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein folding chaperone complex#GO:0101031;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000040273.1|UniProtKB=A0A2I2YPQ1 A0A2I2YPQ1 PTHR23431:SF11 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;zinc ion binding#GO:0008270;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription by RNA polymerase I#GO:0006360;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;RNA polymerase III complex#GO:0005666;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 GORGO|Ensembl=ENSGGOG00000041869.1|UniProtKB=A0A2I2Z3G5 A0A2I2Z3G5 ZNF557 PTHR24381:SF145 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 557 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001285.3|UniProtKB=G3QG21 G3QG21 ITGA2 PTHR23220:SF23 INTEGRIN ALPHA INTEGRIN ALPHA-2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863 GORGO|Ensembl=ENSGGOG00000007826.3|UniProtKB=G3QXU2 G3QXU2 MATN1 PTHR24020:SF16 COLLAGEN ALPHA MATRILIN-1 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000012851.3|UniProtKB=G3RAR4 G3RAR4 ZNF318 PTHR15577:SF2 ZINC FINGER CONTAINING PROTEIN ZINC FINGER PROTEIN 318 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000026365.2|UniProtKB=G3SIH3 G3SIH3 L1TD1 PTHR11505:SF203 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 TYPE TRANSPOSASE DOMAIN-CONTAINING PROTEIN 1 cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000000854.3|UniProtKB=G3QEY5 G3QEY5 ACTR6 PTHR11937:SF47 ACTIN ACTIN-RELATED PROTEIN 6 structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;chromatin binding#GO:0003682;protein-containing complex binding#GO:0044877;structural molecule activity#GO:0005198;nucleosome binding#GO:0031491 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;nucleolus organization#GO:0007000 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000024268.2|UniProtKB=G3RWD1 G3RWD1 TMEM185A PTHR13568:SF2 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 185A dendrite#GO:0030425;dendritic tree#GO:0097447;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477 GORGO|Ensembl=ENSGGOG00000022484.2|UniProtKB=G3RX99 G3RX99 METTL5 PTHR23290:SF0 RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 RRNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL5 rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;ribosome biogenesis#GO:0042254 GORGO|Ensembl=ENSGGOG00000025189.2|UniProtKB=G3RU04 G3RU04 OR5AR1 PTHR26452:SF315 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AR1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005535.3|UniProtKB=A0A2I2Z3F3 A0A2I2Z3F3 TRAPPC12 PTHR21581:SF34 D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000008509.3|UniProtKB=G3QZL0 G3QZL0 KIF7 PTHR24115:SF445 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF7 microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000001532.3|UniProtKB=A0A2I2YF69 A0A2I2YF69 GOLGA7 PTHR13254:SF1 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 GOLGIN SUBFAMILY A MEMBER 7 localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;protein targeting#GO:0006605;Golgi vesicle transport#GO:0048193;transport#GO:0006810;protein targeting to membrane#GO:0006612;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;vesicle-mediated transport#GO:0016192 Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000014228.3|UniProtKB=G3REA5 G3REA5 SPOUT1 PTHR12150:SF14 CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED 28S RRNA (URIDINE-N(3))-METHYLTRANSFERASE binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;centrosome localization#GO:0051642;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;organelle localization#GO:0051640;localization#GO:0051179 intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;membraneless organelle#GO:0043228;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000008408.3|UniProtKB=G3QZA9 G3QZA9 PPP4R2 PTHR16487:SF0 PPP4R2-RELATED PROTEIN SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000043816.1|UniProtKB=G3S3Z6 G3S3Z6 LOC101131398 PTHR20383:SF10 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 LIKE PROTEIN 1-RELATED catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;termination of RNA polymerase II transcription#GO:0006369;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000024269.2|UniProtKB=G3RNX2 G3RNX2 PTHR11352:SF6 PROLIFERATING CELL NUCLEAR ANTIGEN DNA SLIDING CLAMP PCNA enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 DNA-templated DNA replication#GO:0006261;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;DNA replication#GO:0006260;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA polymerase processivity factor#PC00015 GORGO|Ensembl=ENSGGOG00000006747.3|UniProtKB=G3RZZ4 G3RZZ4 RAX PTHR46271:SF3 HOMEOBOX PROTEIN, PUTATIVE-RELATED RETINAL HOMEOBOX PROTEIN RX cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000043663.1|UniProtKB=A0A2I2ZEM9 A0A2I2ZEM9 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED GORGO|Ensembl=ENSGGOG00000024323.2|UniProtKB=A0A2I2YBK6 A0A2I2YBK6 CCDC54 PTHR37880:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 54 COILED-COIL DOMAIN-CONTAINING PROTEIN 54 GORGO|Ensembl=ENSGGOG00000027482.2|UniProtKB=A0A2I2YXA4 A0A2I2YXA4 SRP19 PTHR17453:SF1 SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 protein targeting#GO:0006605;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular component assembly#GO:0022607;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;protein targeting to ER#GO:0045047;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;signal recognition particle, endoplasmic reticulum targeting#GO:0005786 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000027795.2|UniProtKB=G3RW45 G3RW45 IGBP1 PTHR10933:SF12 IMMUNOGLOBULIN-BINDING PROTEIN 1 IMMUNOGLOBULIN-BINDING PROTEIN 1 enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;TOR signaling#GO:0031929;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 p53 pathway by glucose deprivation#P04397>alpha4#P04646 GORGO|Ensembl=ENSGGOG00000036639.1|UniProtKB=A0A2I2Z2N8 A0A2I2Z2N8 PTHR10553:SF26 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 ribonucleoprotein granule#GO:0035770;U1 snRNP#GO:0005685;nucleus#GO:0005634;U12-type spliceosomal complex#GO:0005689;catalytic step 2 spliceosome#GO:0071013;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;U2-type prespliceosome#GO:0071004;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;P granule#GO:0043186;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;U2 snRNP#GO:0005686;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;SMN-Sm protein complex#GO:0034719;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000007542.3|UniProtKB=A0A2I2Y2H6 A0A2I2Y2H6 TFAP2A PTHR10812:SF8 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-ALPHA DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of apoptotic process#GO:0043066;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;renal system development#GO:0072001;kidney development#GO:0001822;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of apoptotic process#GO:0042981;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;positive regulation of metabolic process#GO:0009893;skeletal system development#GO:0001501;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014924.3|UniProtKB=G3RG30 G3RG30 HEMK1 PTHR18895:SF74 HEMK METHYLTRANSFERASE MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;translational termination#GO:0006415;translation#GO:0006412;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006014.4|UniProtKB=G3QT79 G3QT79 COG3 PTHR13302:SF8 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization in cell#GO:0051649;retrograde transport, vesicle recycling within Golgi#GO:0000301 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COG complex#GO:0017119 GORGO|Ensembl=ENSGGOG00000010616.3|UniProtKB=G3R4Y8 G3R4Y8 WDR93 PTHR12219:SF17 NADH-UBIQUINONE OXIDOREDUCTASE WD REPEAT-CONTAINING PROTEIN 93 cellular respiration#GO:0045333;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;electron transport chain#GO:0022900;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000014487.3|UniProtKB=G3REX8 G3REX8 LOC115932194 PTHR14047:SF31 P ANTIGEN FAMILY MEMBER 5-RELATED X ANTIGEN FAMILY MEMBER 1 GORGO|Ensembl=ENSGGOG00000004183.3|UniProtKB=G3QNI4 G3QNI4 HAS3 PTHR22913:SF6 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 3 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;carbohydrate derivative biosynthetic process#GO:1901137;cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;extracellular matrix assembly#GO:0085029;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;aminoglycan metabolic process#GO:0006022;extracellular structure organization#GO:0043062;polysaccharide biosynthetic process#GO:0000271;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;aminoglycan biosynthetic process#GO:0006023;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000043476.1|UniProtKB=A0A2I2ZL73 A0A2I2ZL73 PTHR14495:SF2 SHIELDIN COMPLEX SUBUNIT 2 SHIELDIN COMPLEX SUBUNIT 2 regulation of DNA recombination#GO:0000018;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000039341.1|UniProtKB=A0A2I2ZAF0 A0A2I2ZAF0 PTHR10660:SF7 PROTEASOME REGULATOR PA28 PSME2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase activator activity#GO:0016504;endopeptidase regulator activity#GO:0061135;enzyme activator activity#GO:0008047 regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of protein catabolic process#GO:0042176;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of proteasomal protein catabolic process#GO:0061136;regulation of mitotic cell cycle#GO:0007346;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000013889.3|UniProtKB=G3RDE3 G3RDE3 KLHL29 PTHR24412:SF10 KELCH PROTEIN KELCH-LIKE PROTEIN 29 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000023001.2|UniProtKB=G3SH01 G3SH01 SMARCAD1 PTHR10799:SF964 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A CONTAINING DEAD_H BOX 1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;heterochromatin formation#GO:0031507;cellular response to stimulus#GO:0051716;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;double-strand break repair#GO:0006302;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;DNA metabolic process#GO:0006259;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 DNA metabolism protein#PC00009;DNA helicase#PC00011 GORGO|Ensembl=ENSGGOG00000022395.2|UniProtKB=A0A2I2YCJ4 A0A2I2YCJ4 LOC101142351 PTHR11723:SF18 DNA-BINDING PROTEIN INHIBITOR BHLH DOMAIN-CONTAINING PROTEIN transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 neuron differentiation#GO:0030182;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000006773.3|UniProtKB=G3QV71 G3QV71 NAV1 PTHR12784:SF3 STEERIN NEURON NAVIGATOR 1 cellular component organization#GO:0016043;cell motility#GO:0048870;cell differentiation#GO:0030154;microtubule bundle formation#GO:0001578;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;cell migration#GO:0016477;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;axon#GO:0030424;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;main axon#GO:0044304;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000016274.4|UniProtKB=G3RJI4 G3RJI4 CHRNB3 PTHR18945:SF75 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-3 ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;acetylcholine receptor activity#GO:0015464;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;neuromuscular synaptic transmission#GO:0007274;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536;response to nitrogen compound#GO:1901698;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;trans-synaptic signaling#GO:0099537;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;synaptic transmission, cholinergic#GO:0007271 postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;synapse#GO:0045202;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;transporter complex#GO:1990351;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotine pharmacodynamics pathway#P06587>CHRNB3#P06612 GORGO|Ensembl=ENSGGOG00000036471.1|UniProtKB=A0A2I2ZSZ0 A0A2I2ZSZ0 GID8 PTHR12864:SF85 RAN BINDING PROTEIN 9-RELATED GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;positive regulation of canonical Wnt signaling pathway#GO:0090263;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013936.3|UniProtKB=G3RDK1 G3RDK1 PTHR22957:SF187 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000004291.3|UniProtKB=G3QNT4 G3QNT4 RCBTB2 PTHR22872:SF3 BTK-BINDING PROTEIN-RELATED RCC1 AND BTB DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000002146.3|UniProtKB=G3QIB0 G3QIB0 SKAP2 PTHR15129:SF2 SRC-ASSOCIATED ADAPTOR PROTEIN SRC KINASE-ASSOCIATED PHOSPHOPROTEIN 2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009032.3|UniProtKB=G3R0Y6 G3R0Y6 PTHR43153:SF1 ELECTRON TRANSFER FLAVOPROTEIN ALPHA ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL small molecule binding#GO:0036094;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;lipid modification#GO:0030258;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000014578.3|UniProtKB=G3RF60 G3RF60 NOTO PTHR24339:SF68 HOMEOBOX PROTEIN EMX-RELATED HOMEOBOX PROTEIN NOTOCHORD sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;nervous system development#GO:0007399;head development#GO:0060322;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000004137.3|UniProtKB=G3QNE5 G3QNE5 TUSC1 PTHR34768:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 89 TUMOR SUPPRESSOR CANDIDATE GENE 1 PROTEIN GORGO|Ensembl=ENSGGOG00000007480.3|UniProtKB=A0A2I2Y9Z9 A0A2I2Y9Z9 PTHR31638:SF5 DAZ-ASSOCIATED PROTEIN 2 DAZ-ASSOCIATED PROTEIN 2 GORGO|Ensembl=ENSGGOG00000008064.3|UniProtKB=A0A2I2ZEA9 A0A2I2ZEA9 GNAI1 PTHR10218:SF359 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;signaling receptor binding#GO:0005102;GTPase activity#GO:0003924;protein binding#GO:0005515;hydrolase activity#GO:0016787;G protein-coupled receptor binding#GO:0001664;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 PI3 kinase pathway#P00048>Galpha#P01199;Enkephalin release#P05913>G-Protein (i)#P05974;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Nicotine pharmacodynamics pathway#P06587>GNAI#P06609;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Opioid prodynorphin pathway#P05916>G-protein#P06002;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Gonadotropin-releasing hormone receptor pathway#P06664>gnai/o#P06773;Endogenous cannabinoid signaling#P05730>Galpha#P05751 GORGO|Ensembl=ENSGGOG00000010377.3|UniProtKB=G3R4D0 G3R4D0 SYK PTHR24418:SF231 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SYK phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;antigen receptor-mediated signaling pathway#GO:0050851;myeloid leukocyte activation#GO:0002274;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;cell activation involved in immune response#GO:0002263;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;macrophage activation#GO:0042116;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;adaptive immune response#GO:0002250;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;regulation of immune response#GO:0050776;cell activation#GO:0001775;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of cell adhesion#GO:0045785;leukocyte activation#GO:0045321 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Syk#P00382 GORGO|Ensembl=ENSGGOG00000022206.2|UniProtKB=G3S104 G3S104 PTHR14633:SF3 LITTLE ELONGATION COMPLEX SUBUNIT 2 LITTLE ELONGATION COMPLEX SUBUNIT 2 regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;transcription by RNA polymerase II#GO:0006366;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase III#GO:0042796;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nucleic acid biosynthetic process#GO:0141187;snRNA transcription#GO:0009301;transcription by RNA polymerase III#GO:0006383;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000007398.3|UniProtKB=A0A2I2Z4R1 A0A2I2Z4R1 CDH24 PTHR24027:SF272 CADHERIN-23 CADHERIN-24 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell junction organization#GO:0034330;cell motility#GO:0048870;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043 anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000013292.3|UniProtKB=G3S2A2 G3S2A2 PTHR14559:SF12 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 10 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003011.3|UniProtKB=A0A2I2ZMW3 A0A2I2ZMW3 CTTN PTHR10829:SF15 CORTACTIN AND DREBRIN SRC SUBSTRATE CORTACTIN binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 neuron development#GO:0048666;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;cell-matrix adhesion#GO:0007160;regulation of actin filament length#GO:0030832;generation of neurons#GO:0048699;cell adhesion#GO:0007155;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;regulation of anatomical structure size#GO:0090066;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;system development#GO:0048731;synapse organization#GO:0050808;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;cell junction organization#GO:0034330;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell-substrate junction assembly#GO:0007044;regulation of supramolecular fiber organization#GO:1902903;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of actin filament-based process#GO:0032970;cell-substrate junction organization#GO:0150115;developmental process#GO:0032502;focal adhesion assembly#GO:0048041;neuron projection morphogenesis#GO:0048812;regulation of actin filament polymerization#GO:0030833;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin filament organization#GO:0110053 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;glutamatergic synapse#GO:0098978;lamellipodium#GO:0030027;supramolecular complex#GO:0099080;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoskeleton#GO:0005856;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;supramolecular fiber#GO:0099512 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000038678.1|UniProtKB=G3RD21 G3RD21 APOBEC3F PTHR13857:SF45 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3F nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity#GO:0016787;RNA binding#GO:0003723;catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;base conversion or substitution editing#GO:0016553;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;biological process involved in interspecies interaction between organisms#GO:0044419;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;response to external stimulus#GO:0009605;defense response#GO:0006952;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;macromolecule modification#GO:0043412;response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cytidine to uridine editing#GO:0016554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000015327.3|UniProtKB=G3RH36 G3RH36 LOC101154093 PTHR31943:SF14 INTERLEUKIN-28 AND 29 INTERFERON LAMBDA-1 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 immune system process#GO:0002376;innate immune response#GO:0045087;response to virus#GO:0009615;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;defense response to virus#GO:0051607;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;interleukin superfamily#PC00128;cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000012005.3|UniProtKB=G3R8J8 G3R8J8 LOC101152037 PTHR44427:SF32 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 IG-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000016422.3|UniProtKB=G3RJX0 G3RJX0 FAM151B PTHR21184:SF3 MENORIN (DENDRITIC BRANCHING PROTEIN) PROTEIN FAM151B cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000010811.3|UniProtKB=G3S896 G3S896 RILPL2 PTHR21502:SF2 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN 2 enzyme binding#GO:0019899;binding#GO:0005488;small GTPase binding#GO:0031267;protein binding#GO:0005515 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000011896.3|UniProtKB=G3R8A2 G3R8A2 SLC3A1 PTHR10357:SF240 ALPHA-GLUCOSIDASE FAMILY MEMBER AMINO ACID TRANSPORTER HEAVY CHAIN SLC3A1 oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987;establishment of localization#GO:0051234;localization#GO:0051179;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;amino acid transport#GO:0006865;transport#GO:0006810 membrane#GO:0016020;apical plasma membrane#GO:0016324;brush border#GO:0005903;cell periphery#GO:0071944;brush border membrane#GO:0031526;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;apical part of cell#GO:0045177;cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862 amylase#PC00048;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000009391.3|UniProtKB=G3SCJ5 G3SCJ5 TMEM94 PTHR13219:SF6 TRANSMEMBRANE PROTEIN 94 TRANSMEMBRANE PROTEIN 94 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;magnesium ion transmembrane transporter activity#GO:0015095;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;magnesium ion transport#GO:0015693;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000040299.1|UniProtKB=G3RI59 G3RI59 LOC101142073 PTHR26452:SF418 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5J2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000012388.3|UniProtKB=G3R9K5 G3R9K5 FADS3 PTHR19353:SF11 FATTY ACID DESATURASE 2 FATTY ACID DESATURASE 3 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000002392.3|UniProtKB=G3QIY1 G3QIY1 TIGD5 PTHR19303:SF56 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000016948.3|UniProtKB=G3RL98 G3RL98 OR5C1 PTHR26452:SF119 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5C1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000003284.3|UniProtKB=G3QL81 G3QL81 MUTYH PTHR42944:SF1 ADENINE DNA GLYCOSYLASE ADENINE DNA GLYCOSYLASE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;damaged DNA binding#GO:0003684;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA N-glycosylase activity#GO:0019104;DNA binding#GO:0003677;hydrolase activity#GO:0016787;double-stranded DNA binding#GO:0003690 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 GORGO|Ensembl=ENSGGOG00000015003.3|UniProtKB=G3RGA8 G3RGA8 LAMA4 PTHR15036:SF47 PIKACHURIN-LIKE PROTEIN LAMININ SUBUNIT ALPHA-4 biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;developmental process#GO:0032502;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 cell junction#GO:0030054;extracellular region#GO:0005576;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;basement membrane#GO:0005604;cell periphery#GO:0071944;external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012 cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000023775.2|UniProtKB=G3RNN5 G3RNN5 PTHR23410:SF24 RIBOSOMAL PROTEIN L5-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL18 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 regulation of protein metabolic process#GO:0051246;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;ribosomal large subunit assembly#GO:0000027;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016835.3|UniProtKB=G3RKZ2 G3RKZ2 FABP12 PTHR11955:SF76 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 12 ion binding#GO:0043167;carboxylic acid binding#GO:0031406;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289 lipid transport#GO:0006869;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000042588.1|UniProtKB=G3S3E2 G3S3E2 COMMD5 PTHR15666:SF3 COMM DOMAIN CONTAINING PROTEIN 5 COMM DOMAIN-CONTAINING PROTEIN 5 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000027241.2|UniProtKB=G3SCU3 G3SCU3 DUSP6 PTHR10159:SF45 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 6 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;regulation of growth#GO:0040008;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;positive regulation of apoptotic process#GO:0043065 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000043279.1|UniProtKB=A0A2I2ZR51 A0A2I2ZR51 FKRP PTHR13627:SF31 FUKUTIN RELATED PROTEIN RIBITOL 5-PHOSPHATE TRANSFERASE FKRP transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 GORGO|Ensembl=ENSGGOG00000013514.3|UniProtKB=G3RCG4 G3RCG4 RTF1 PTHR13115:SF8 RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325 intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593 GORGO|Ensembl=ENSGGOG00000011667.3|UniProtKB=G3R7N5 G3R7N5 DNAJC5G PTHR44027:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5G chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000022574.2|UniProtKB=A0A2I2Y5M1 A0A2I2Y5M1 PTHR46029:SF5 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 2 transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000002911.3|UniProtKB=G3QK93 G3QK93 UVRAG PTHR15157:SF5 UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;autophagy#GO:0006914;organophosphate metabolic process#GO:0019637;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol phosphate biosynthetic process#GO:0046854;process utilizing autophagic mechanism#GO:0061919;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endosome#GO:0005768;phosphatidylinositol 3-kinase complex, class III#GO:0035032;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;lytic vacuole#GO:0000323;extrinsic component of membrane#GO:0019898;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000009143.3|UniProtKB=G3R180 G3R180 LGALS7 PTHR11346:SF107 GALECTIN GALECTIN-7 binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000037358.1|UniProtKB=A0A2I2YEE9 A0A2I2YEE9 PTHR13440:SF9 BLOC-1 RELATED COMPLEX SUBUNIT 6 SUBFAMILY NOT NAMED localization#GO:0051179;organelle localization#GO:0051640;lysosome localization#GO:0032418 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000037678.1|UniProtKB=A0A2I2ZBI0 A0A2I2ZBI0 PTHR13809:SF14 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 extrinsic component of membrane#GO:0019898;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 heterotrimeric G-protein#PC00117 Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Nicotine pharmacodynamics pathway#P06587>GNG#P06590;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974 GORGO|Ensembl=ENSGGOG00000004300.3|UniProtKB=G3QNU5 G3QNU5 NCL PTHR48034:SF4 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED NUCLEOLIN binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012379.3|UniProtKB=A0A2I2YYY7 A0A2I2YYY7 P2RX3 PTHR10125:SF8 P2X PURINOCEPTOR P2X PURINOCEPTOR 3 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000037950.1|UniProtKB=A0A2I2YN04 A0A2I2YN04 PAIP2B PTHR13154:SF5 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2B translation regulator activity#GO:0045182 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of translation#GO:0017148;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000000320.3|UniProtKB=A0A2I2YJS4 A0A2I2YJS4 TRIP12 PTHR45670:SF13 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 cellular process#GO:0009987;response to stress#GO:0006950;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;DNA damage response#GO:0006974;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012710.3|UniProtKB=A0A2I2Z566 A0A2I2Z566 PLK2 PTHR24345:SF44 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 G1/S transition of mitotic cell cycle#GO:0000082;regulation of synaptic plasticity#GO:0048167;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;mitotic cell cycle phase transition#GO:0044772;regulation of biological quality#GO:0065008;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000006102.3|UniProtKB=G3QTG6 G3QTG6 ITGAD PTHR23220:SF132 INTEGRIN ALPHA INTEGRIN ALPHA-D signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589 integrin complex#GO:0008305;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000042532.1|UniProtKB=A0A2I2Z6M4 A0A2I2Z6M4 SMIM13 PTHR36877:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 13 SMALL INTEGRAL MEMBRANE PROTEIN 13 GORGO|Ensembl=ENSGGOG00000004979.3|UniProtKB=G3QQL0 G3QQL0 ASPHD2 PTHR46332:SF3 ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 hydroxylase#PC00122;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000037780.1|UniProtKB=A0A2I2ZED8 A0A2I2ZED8 AP5Z1 PTHR46488:SF1 AP-5 COMPLEX SUBUNIT ZETA-1 AP-5 COMPLEX SUBUNIT ZETA-1 GORGO|Ensembl=ENSGGOG00000025095.2|UniProtKB=G3RTK3 G3RTK3 GTF2H5 PTHR28580:SF1 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;protein-containing complex assembly#GO:0065003;response to stimulus#GO:0050896;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;protein-DNA complex assembly#GO:0065004 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transcription factor TFIIH core complex#GO:0000439;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription regulator complex#GO:0005667 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000040331.1|UniProtKB=G3SCT2 G3SCT2 TCTA PTHR32267:SF2 T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN GORGO|Ensembl=ENSGGOG00000024002.2|UniProtKB=A0A2I2ZD74 A0A2I2ZD74 OR9Q1 PTHR48018:SF60 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9Q1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016596.3|UniProtKB=A0A2I2ZSJ9 A0A2I2ZSJ9 KIF5C PTHR24115:SF380 KINESIN-RELATED KINESIN HEAVY CHAIN ISOFORM 5C protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 synaptic vesicle transport#GO:0048489;neuron projection development#GO:0031175;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle localization#GO:0097479;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;anatomical structure morphogenesis#GO:0009653;establishment of organelle localization#GO:0051656;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;neuron development#GO:0048666;axonogenesis#GO:0007409;axon development#GO:0061564;axon guidance#GO:0007411;axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;mitochondrion localization#GO:0051646;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;vesicle cytoskeletal trafficking#GO:0099518;microtubule-based movement#GO:0007018;organelle localization#GO:0051640;axonal transport#GO:0098930;anatomical structure development#GO:0048856;localization#GO:0051179;anterograde axonal transport#GO:0008089;system development#GO:0048731 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000022474.2|UniProtKB=G3SC30 G3SC30 ZNF891 PTHR24381:SF76 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 891 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000012083.3|UniProtKB=G3R8S5 G3R8S5 ZFHX3 PTHR45891:SF4 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000038643.1|UniProtKB=A0A2I2Y643 A0A2I2Y643 PTHR12801:SF22 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED EXONUCLEASE GOR-RELATED catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000013730.3|UniProtKB=A0A2I2YEM7 A0A2I2YEM7 PTHR11254:SF443 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;transporter regulator activity#GO:0141108;ubiquitin protein ligase activity#GO:0061630;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755 metabolic process#GO:0008152;regulation of cell projection organization#GO:0031344;macromolecule catabolic process#GO:0009057;regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;biological regulation#GO:0065007;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of dendrite morphogenesis#GO:0048814;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000008699.3|UniProtKB=G3S798 G3S798 ABCB10 PTHR43394:SF29 ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL pigment metabolic process#GO:0042440;regulation of cell development#GO:0060284;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of myeloid cell differentiation#GO:0045639;regulation of multicellular organismal process#GO:0051239;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;positive regulation of cell differentiation#GO:0045597;porphyrin-containing compound metabolic process#GO:0006778;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;pigment biosynthetic process#GO:0046148;heme biosynthetic process#GO:0006783;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;tetrapyrrole biosynthetic process#GO:0033014;regulation of developmental process#GO:0050793;regulation of myeloid cell differentiation#GO:0045637;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound biosynthetic process#GO:0006779;regulation of hemopoiesis#GO:1903706 mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000010660.3|UniProtKB=G3SES5 G3SES5 SLC2A2 PTHR23503:SF27 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 2 carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;import across plasma membrane#GO:0098739;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643 cluster of actin-based cell projections#GO:0098862;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;brush border#GO:0005903;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000002840.3|UniProtKB=G3QK31 G3QK31 PTHR10811:SF110 FRINGE-RELATED BETA-1,3-GLUCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000010145.3|UniProtKB=G3R3R8 G3R3R8 NFATC3 PTHR12533:SF6 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;calcium-mediated signaling#GO:0019722;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 immunoglobulin fold transcription factor#PC00251;gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;B cell activation#P00010>NFAT#P00367;T cell activation#P00053>NFAT#P01294;Axon guidance mediated by netrin#P00009>NFAT#P00359;Wnt signaling pathway#P00057>NFAT#P01452 GORGO|Ensembl=ENSGGOG00000015593.3|UniProtKB=G3S3T5 G3S3T5 AP2B1 PTHR11134:SF9 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-2 COMPLEX SUBUNIT BETA protein-macromolecule adaptor activity#GO:0030674;clathrin binding#GO:0030276;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898 Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;endocytic vesicle#GO:0030139;coated membrane#GO:0048475;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vesicle coat#GO:0030120;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;membrane protein complex#GO:0098796;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000040956.1|UniProtKB=G3RX21 G3RX21 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 aspartic protease#PC00053;protease#PC00190 GORGO|Gene=ERVFRD-1|UniProtKB=P61554 P61554 ERVFRD-1 PTHR10424:SF85 VIRAL ENVELOPE PROTEIN SYNCYTIN-2 developmental process#GO:0032502;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;striated muscle cell differentiation#GO:0051146;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;myoblast fusion#GO:0007520;cell differentiation#GO:0030154;muscle structure development#GO:0061061 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000012304.3|UniProtKB=G3R9F3 G3R9F3 MUC5B PTHR11339:SF408 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-5B extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000004385.3|UniProtKB=G3QP22 G3QP22 INTS2 PTHR28608:SF1 INTEGRATOR COMPLEX SUBUNIT 2 INTEGRATOR COMPLEX SUBUNIT 2 nucleobase-containing compound catabolic process#GO:0034655;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;snRNA processing#GO:0016180;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;DNA-templated transcription#GO:0006351;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;integrator complex#GO:0032039;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000022658.2|UniProtKB=G3S9N7 G3S9N7 LSM1 PTHR15588:SF8 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000009754.3|UniProtKB=G3R2R9 G3R2R9 NCDN PTHR13109:SF8 NEUROCHONDRIN NEUROCHONDRIN anatomical structure development#GO:0048856;neuron development#GO:0048666;regulation of biological quality#GO:0065008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of neuronal synaptic plasticity#GO:0048168;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;regulation of synaptic plasticity#GO:0048167;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;neuron projection development#GO:0031175;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;neuron projection#GO:0043005;dendritic tree#GO:0097447 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003974.3|UniProtKB=G3QN00 G3QN00 AXIN2 PTHR46102:SF1 AXIN AXIN-2 kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;beta-catenin binding#GO:0008013;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625 negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;cellular developmental process#GO:0048869;regulation of catabolic process#GO:0009894;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;anatomical structure development#GO:0048856;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of cell cycle process#GO:0010564;negative regulation of signal transduction#GO:0009968;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of cell cycle#GO:0051726;regulation of Wnt signaling pathway#GO:0030111;cell development#GO:0048468;positive regulation of proteasomal protein catabolic process#GO:1901800;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051 membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Axin#P01429 GORGO|Ensembl=ENSGGOG00000015039.3|UniProtKB=A0A2I2Y2N5 A0A2I2Y2N5 FBXL17 PTHR13382:SF72 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B F-BOX AND LEUCINE-RICH REPEAT PROTEIN 17 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000025760.2|UniProtKB=G3SFA3 G3SFA3 GP1BB PTHR22650:SF7 GLYCOPROTEIN IB BETA PLATELET GLYCOPROTEIN IB BETA CHAIN Blood coagulation#P00011>GP 1bbeta#P00436 GORGO|Ensembl=ENSGGOG00000002072.3|UniProtKB=G3QI39 G3QI39 AP3M2 PTHR10529:SF341 AP COMPLEX SUBUNIT MU AP-3 COMPLEX SUBUNIT MU-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;AP-type membrane coat adaptor complex#GO:0030119;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Gene=TWIST1|UniProtKB=Q8MI06 Q8MI06 TWIST1 PTHR23349:SF64 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TWIST-RELATED PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000025477.2|UniProtKB=G3SAT4 G3SAT4 PTHR11476:SF11 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000038293.1|UniProtKB=G3R1E5 G3R1E5 MYH4 PTHR45615:SF79 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-4 cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 muscle contraction#GO:0006936;muscle system process#GO:0003012;multicellular organismal process#GO:0032501;system process#GO:0003008 actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000001278.3|UniProtKB=G3QG13 G3QG13 APMAP PTHR10426:SF130 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 GORGO|Ensembl=ENSGGOG00000012824.3|UniProtKB=G3RAP5 G3RAP5 ECT2L PTHR46857:SF1 EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE GORGO|Ensembl=ENSGGOG00000015639.4|UniProtKB=G3RHY4 G3RHY4 LPCAT1 PTHR23063:SF57 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000041047.1|UniProtKB=G3RIE2 G3RIE2 LOC101154047 PTHR13759:SF9 TWINFILIN TWINFILIN-2 actin monomer binding#GO:0003785;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;cellular component disassembly#GO:0022411;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;positive regulation of neuron projection development#GO:0010976;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;actin filament depolymerization#GO:0030042;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament depolymerization#GO:0030834;protein-containing complex disassembly#GO:0032984;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cell projection assembly#GO:0060491;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;positive regulation of cell projection organization#GO:0031346;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of protein depolymerization#GO:1901880;protein depolymerization#GO:0051261;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;positive regulation of cellular process#GO:0048522;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344 contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;actin filament#GO:0005884;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000025693.2|UniProtKB=G3S993 G3S993 PTHR24409:SF361 ZINC FINGER PROTEIN 142 VASCULAR ENDOTHELIAL ZINC FINGER 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000041924.1|UniProtKB=G3RYQ4 G3RYQ4 HSD17B10 PTHR43658:SF17 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 3-HYDROXYACYL-COA DEHYDROGENASE TYPE-2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 regulation of biological quality#GO:0065008;estrogen metabolic process#GO:0008210;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;small molecule metabolic process#GO:0044281;hormone metabolic process#GO:0042445;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000011126.3|UniProtKB=G3R6A3 G3R6A3 PGLYRP1 PTHR11022:SF58 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN RECOGNITION PROTEIN 1 catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787 defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000012542.3|UniProtKB=G3R9Y9 G3R9Y9 UBN1 PTHR21669:SF12 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS UBINUCLEIN-1 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001957.3|UniProtKB=G3QHU0 G3QHU0 PHOSPHO1 PTHR20889:SF2 PHOSPHATASE, ORPHAN 1, 2 PHOSPHOETHANOLAMINE_PHOSPHOCHOLINE PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 animal gross anatomical part developmental process#GO:0160108;biomineral tissue development#GO:0031214;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure maturation#GO:0071695;animal organ morphogenesis#GO:0009887;ossification#GO:0001503;bone mineralization#GO:0030282;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;skeletal system morphogenesis#GO:0048705;bone development#GO:0060348;developmental maturation#GO:0021700;tissue development#GO:0009888;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;membrane-bounded organelle#GO:0043227;organelle#GO:0043226;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000012535.3|UniProtKB=G3R9Y6 G3R9Y6 GORASP2 PTHR12893:SF1 GOLGI REASSEMBLY STACKING PROTEIN GRASP GOLGI REASSEMBLY-STACKING PROTEIN 2 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015473.3|UniProtKB=G3RHH1 G3RHH1 AANAT PTHR10908:SF7 SEROTONIN N-ACETYLTRANSFERASE SEROTONIN N-ACETYLTRANSFERASE N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 response to abiotic stimulus#GO:0009628;response to radiation#GO:0009314;rhythmic process#GO:0048511;photoperiodism#GO:0009648;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;circadian rhythm#GO:0007623 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000008626.3|UniProtKB=G3QZW7 G3QZW7 PRKCSH PTHR12630:SF27 N-LINKED OLIGOSACCHARIDE PROCESSING GLUCOSIDASE 2 SUBUNIT BETA system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;animal gross anatomical part developmental process#GO:0160108;liver development#GO:0001889;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;animal organ development#GO:0048513;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;developmental process#GO:0032502;metabolic process#GO:0008152;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000007888.3|UniProtKB=G3QXZ5 G3QXZ5 PTHR24120:SF8 GH07239P ANKYRIN REPEAT AND SOCS BOX PROTEIN 12 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000000716.3|UniProtKB=G3QEK8 G3QEK8 POMGNT2 PTHR20961:SF167 GLYCOSYLTRANSFERASE PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000026472.2|UniProtKB=A0A2I2YMT7 A0A2I2YMT7 PTHR11811:SF48 6-PHOSPHOGLUCONATE DEHYDROGENASE 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;phosphogluconate dehydrogenase (decarboxylating) activity#GO:0004616;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt#GO:0006098;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;pentose-phosphate shunt, oxidative branch#GO:0009051;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000039663.1|UniProtKB=G3SFL0 G3SFL0 H2BC13 PTHR23428:SF190 HISTONE H2B HISTONE H2B TYPE 1-L response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to other organism#GO:0051707 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000013212.3|UniProtKB=G3RBR1 G3RBR1 HSPG2 PTHR11640:SF156 NEPHRIN BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000014036.3|UniProtKB=G3RDU1 G3RDU1 MCF2L PTHR22826:SF115 RHO GUANINE EXCHANGE FACTOR-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000001981.3|UniProtKB=G3RQD4 G3RQD4 CEACAM4 PTHR44427:SF8 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM4 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000040896.1|UniProtKB=A0A2I2Z7M4 A0A2I2Z7M4 RAB33B PTHR47978:SF26 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33B GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 metabolic process#GO:0008152;regulation of localization#GO:0032879;regulation of transport#GO:0051049;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;biological regulation#GO:0065007;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;Golgi apparatus#GO:0005794 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000016398.3|UniProtKB=G3RJU8 G3RJU8 RSPH14 PTHR15599:SF1 RTDR1 RADIAL SPOKE HEAD 14 HOMOLOG GORGO|Ensembl=ENSGGOG00000009707.3|UniProtKB=G3R2M5 G3R2M5 KRT28 PTHR23239:SF215 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 28 structural molecule activity#GO:0005198 cellular process#GO:0009987;organelle organization#GO:0006996;skin development#GO:0043588;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;developmental process#GO:0032502;epidermis development#GO:0008544;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856 intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000015748.3|UniProtKB=A0A2I2ZDD6 A0A2I2ZDD6 MATN2 PTHR24034:SF155 EGF-LIKE DOMAIN-CONTAINING PROTEIN MATRILIN 2 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000004907.3|UniProtKB=G3QQE2 G3QQE2 SHROOM3 PTHR15012:SF33 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM3 actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cortical cytoskeleton#GO:0030863;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;plasma membrane region#GO:0098590;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical junction complex#GO:0043296;apical part of cell#GO:0045177 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000016040.3|UniProtKB=G3RIY2 G3RIY2 GNAL PTHR10218:SF233 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(OLF) SUBUNIT ALPHA hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;sensory perception#GO:0007600;response to oxygen-containing compound#GO:1901700;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212;system process#GO:0003008;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;sensory perception of chemical stimulus#GO:0007606 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737 G-protein#PC00020;heterotrimeric G-protein#PC00117 Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gsalpha#P00705;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Endothelin signaling pathway#P00019>Gs#P00584;Enkephalin release#P05913>G-Protein (s)#P05977 GORGO|Ensembl=ENSGGOG00000040233.1|UniProtKB=G3SE67 G3SE67 PTHR23266:SF297 IMMUNOGLOBULIN HEAVY CHAIN NON-FUNCTIONAL IMMUNOGLOBULIN HEAVY VARIABLE 1-38-4-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015137.3|UniProtKB=A0A2I2ZCK4 A0A2I2ZCK4 FAM3B PTHR14592:SF2 UNCHARACTERIZED FAM3 PROTEIN FAM3B signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000002097.3|UniProtKB=G3QI63 G3QI63 FBXO44 PTHR12125:SF13 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 44 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016545.3|UniProtKB=G3S5Y8 G3S5Y8 SEPTIN5 PTHR18884:SF68 SEPTIN SEPTIN-5 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;intracellular protein localization#GO:0008104;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cell cycle process#GO:0022402;cell division#GO:0051301;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;cytokinesis#GO:0000910;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179 membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;presynapse#GO:0098793;secretory vesicle#GO:0099503;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cell cortex#GO:0005938;intracellular vesicle#GO:0097708 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 GORGO|Ensembl=ENSGGOG00000001244.3|UniProtKB=G3QFY7 G3QFY7 PRDM4 PTHR16515:SF2 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 4 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000016674.3|UniProtKB=A0A2I2ZJL8 A0A2I2ZJL8 MGMT PTHR46460:SF1 METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011650.3|UniProtKB=G3R7M4 G3R7M4 VPS37A PTHR13678:SF20 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A localization within membrane#GO:0051668;protein localization to vacuole#GO:0072665;localization#GO:0051179;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein transport#GO:0015031;cellular localization#GO:0051641;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;protein targeting to membrane#GO:0006612;macromolecule catabolic process#GO:0009057;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;protein targeting to vacuole#GO:0006623 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000038120.1|UniProtKB=A0A2I2Z7S4 A0A2I2Z7S4 PTHR19367:SF31 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-1 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000025054.2|UniProtKB=G3S6R4 G3S6R4 ADRA2A PTHR24248:SF24 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2A ADRENERGIC RECEPTOR cation binding#GO:0043169;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;hormone binding#GO:0042562 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 GORGO|Ensembl=ENSGGOG00000004356.3|UniProtKB=G3SH11 G3SH11 STK39 PTHR48012:SF14 STERILE20-LIKE KINASE, ISOFORM B-RELATED STE20_SPS1-RELATED PROLINE-ALANINE-RICH PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular response to chemical stress#GO:0062197;cellular response to abiotic stimulus#GO:0071214;positive regulation of response to external stimulus#GO:0032103;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;response to abiotic stimulus#GO:0009628;positive regulation of locomotion#GO:0040017;response to osmotic stress#GO:0006970;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of chemotaxis#GO:0050921;regulation of lymphocyte migration#GO:2000401;cellular response to osmotic stress#GO:0071470;hyperosmotic response#GO:0006972;regulation of leukocyte migration#GO:0002685;regulation of immune system process#GO:0002682;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003223.3|UniProtKB=G3QL25 G3QL25 ENKUR PTHR21490:SF0 ENKURIN-RELATED ENKURIN protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;secretory vesicle#GO:0099503;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;cytoplasmic microtubule#GO:0005881;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000023932.2|UniProtKB=G3SDM2 G3SDM2 LOC101146129 PTHR11961:SF15 CYTOCHROME C CYTOCHROME C, SOMATIC aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ATP synthesis#P02721>Cyt C#P02798;Apoptosis signaling pathway#P00006>Cytochrome C#P00322 GORGO|Ensembl=ENSGGOG00000005882.3|UniProtKB=G3QSW1 G3QSW1 DDX47 PTHR24031:SF790 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX47-RELATED metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005915.3|UniProtKB=G3QSY7 G3QSY7 EDA PTHR15151:SF13 PROTEIN EIGER ECTODYSPLASIN-A cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 anatomical structure development#GO:0048856;animal organ development#GO:0048513;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;response to stimulus#GO:0050896;odontogenesis of dentin-containing tooth#GO:0042475;animal organ morphogenesis#GO:0009887;odontogenesis#GO:0042476;anatomical structure morphogenesis#GO:0009653;immune response#GO:0006955 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000038246.1|UniProtKB=A0A2I2ZL26 A0A2I2ZL26 LOC109026809 PTHR10286:SF47 INORGANIC PYROPHOSPHATASE INORGANIC PYROPHOSPHATASE hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 pyrophosphatase#PC00196 GORGO|Ensembl=ENSGGOG00000040615.1|UniProtKB=A0A2I2YB05 A0A2I2YB05 CCNT2 PTHR10026:SF43 CYCLIN CYCLIN-T2 kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription elongation#GO:0032784 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991 kinase modulator#PC00140;kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000037222.1|UniProtKB=A0A2I2YVU2 A0A2I2YVU2 NCF1 PTHR15706:SF6 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 1-RELATED enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;superoxide metabolic process#GO:0006801 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002901.3|UniProtKB=A0A2I2YJ45 A0A2I2YJ45 OGA PTHR13170:SF16 O-GLCNACASE PROTEIN O-GLCNACASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000028544.2|UniProtKB=G3RRZ6 G3RRZ6 TAF5L PTHR19879:SF6 TRANSCRIPTION INITIATION FACTOR TFIID TAF5-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 5L structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of primary metabolic process#GO:0080090;transcription initiation at RNA polymerase II promoter#GO:0006367;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;peptidase complex#GO:1905368;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;acetyltransferase complex#GO:1902493;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000004835.3|UniProtKB=G3QQ76 G3QQ76 NLRP3 PTHR45690:SF25 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 3 transcription factor binding#GO:0008134;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;sequence-specific DNA binding#GO:0043565 negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;canonical inflammasome complex#GO:0061702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000012905.3|UniProtKB=G3RAW0 G3RAW0 ACP3 PTHR11567:SF221 ACID PHOSPHATASE-RELATED PROSTATIC ACID PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;acid phosphatase activity#GO:0003993;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 positive regulation of response to stimulus#GO:0048584;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of system process#GO:0044057;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000034918.2|UniProtKB=G3SKI9 G3SKI9 TSPAN12 PTHR19282:SF462 TETRASPANIN TETRASPANIN-12 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015141.3|UniProtKB=G3RGN3 G3RGN3 ROBO4 PTHR10075:SF146 BASIGIN RELATED ROUNDABOUT HOMOLOG 4 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000037421.1|UniProtKB=A0A2I2Y9X2 A0A2I2Y9X2 AARD PTHR32289:SF2 PROTEIN FAM167A ALANINE- AND ARGININE-RICH DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;response to chemical#GO:0042221;response to lipid#GO:0033993;response to oxygen-containing compound#GO:1901700 GORGO|Ensembl=ENSGGOG00000015764.3|UniProtKB=G3RI84 G3RI84 FAM25A PTHR34994:SF1 PROTEIN FAM25A-RELATED PROTEIN FAM25A-RELATED GORGO|Ensembl=ENSGGOG00000012331.3|UniProtKB=G3R9G1 G3R9G1 CDH17 PTHR24027:SF419 CADHERIN-23 CADHERIN-17 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cell migration#GO:0016477;cell motility#GO:0048870;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000007132.3|UniProtKB=A0A2I2ZAE4 A0A2I2ZAE4 CACNA2D2 PTHR10166:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-2 transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000006625.3|UniProtKB=G3QUT5 G3QUT5 PLXNB2 PTHR22625:SF9 PLEXIN PLEXIN-B2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cell adhesion#GO:0007162;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;system development#GO:0048731;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of axonogenesis#GO:0050770;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;positive regulation of axonogenesis#GO:0050772;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;response to stimulus#GO:0050896;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;synapse assembly#GO:0007416;signaling#GO:0023052;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008687.3|UniProtKB=A0A2I2Y2R3 A0A2I2Y2R3 DYNLRB2 PTHR10779:SF31 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000016963.3|UniProtKB=G3RLB0 G3RLB0 IL18BP PTHR14292:SF2 INTERLEUKIN-18-BINDING PROTEIN INTERLEUKIN-18-BINDING PROTEIN binding#GO:0005488;protein binding#GO:0005515;cytokine binding#GO:0019955 response to stimulus#GO:0050896;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune response#GO:0006955 extracellular region#GO:0005576;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000003451.3|UniProtKB=G3QLN4 G3QLN4 CAMKK2 PTHR24343:SF539 SERINE/THREONINE KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000024273.3|UniProtKB=G3RYY5 G3RYY5 DNAI3 PTHR12442:SF5 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 3 protein binding#GO:0005515;binding#GO:0005488 organelle assembly#GO:0070925;inner dynein arm assembly#GO:0036159;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cell motility#GO:0048870;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;inner dynein arm#GO:0036156 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000003145.3|UniProtKB=G3QKV9 G3QKV9 TBC1D13 PTHR22957:SF27 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 13 GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000003920.3|UniProtKB=G3RTH7 G3RTH7 SLC22A8 PTHR24064:SF439 SOLUTE CARRIER FAMILY 22 MEMBER ORGANIC ANION TRANSPORTER 3 active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000002325.3|UniProtKB=G3QIS2 G3QIS2 PBX2 PTHR11850:SF50 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 2 transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryonic organ development#GO:0048568;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;neuron development#GO:0048666;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell development#GO:0048468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;positive regulation of macromolecule metabolic process#GO:0010604;head development#GO:0060322;embryo development#GO:0009790;nervous system development#GO:0007399;sensory system development#GO:0048880;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000012550.3|UniProtKB=A0A2I2Z2K5 A0A2I2Z2K5 UCK1 PTHR10285:SF66 URIDINE KINASE URIDINE-CYTIDINE KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleoside kinase activity#GO:0019206;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 GORGO|Ensembl=ENSGGOG00000023525.2|UniProtKB=A0A2I2Y5A9 A0A2I2Y5A9 PTHR13085:SF3 MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 2 metabolic process#GO:0008152;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;protein targeting to ER#GO:0045047;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of protein localization#GO:0045184;gene expression#GO:0010467;protein maturation#GO:0051604;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;protein targeting#GO:0006605 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;membrane#GO:0016020 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 GORGO|Ensembl=ENSGGOG00000039689.1|UniProtKB=A0A2I2ZHV3 A0A2I2ZHV3 LOC101135678 PTHR48001:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1J2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043596.1|UniProtKB=A0A2I2YTN1 A0A2I2YTN1 JDP2 PTHR23351:SF10 FOS TRANSCRIPTION FACTOR-RELATED JUN DIMERIZATION PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302 GORGO|Ensembl=ENSGGOG00000000923.3|UniProtKB=G3QF47 G3QF47 CD320 PTHR24270:SF62 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED CD320 ANTIGEN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000009881.3|UniProtKB=G3R359 G3R359 NLRC5 PTHR24107:SF28 YNEIN REGULATORY COMPLEX SUBUNIT 5 PROTEIN NLRC5 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000039456.1|UniProtKB=A0A2I2YSV4 A0A2I2YSV4 PTHR24070:SF174 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-A hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;regulation of secretion#GO:0051046;intracellular signal transduction#GO:0035556;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of transport#GO:0051049;regulation of localization#GO:0032879;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 Ras Pathway#P04393>Ral#P04550 GORGO|Ensembl=ENSGGOG00000022653.2|UniProtKB=G3S9A1 G3S9A1 RPL28 PTHR10544:SF10 60S RIBOSOMAL PROTEIN L28 LARGE RIBOSOMAL SUBUNIT PROTEIN EL28 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000001451.3|UniProtKB=G3QGH6 G3QGH6 VPS37D PTHR13678:SF12 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37D modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;localization within membrane#GO:0051668;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein transport#GO:0015031;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein targeting to vacuole#GO:0006623;establishment of protein localization to membrane#GO:0090150;intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;protein targeting to membrane#GO:0006612;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000028333.2|UniProtKB=G3RZZ3 G3RZZ3 ZNF580 PTHR24393:SF54 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 580 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000006272.3|UniProtKB=G3RS07 G3RS07 PTHR11929:SF165 ALPHA- 1,3 -FUCOSYLTRANSFERASE 3-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 4-ALPHA-L-FUCOSYLTRANSFERASE FUT3 glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920;catalytic activity#GO:0003824;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000027976.2|UniProtKB=G3RQ06 G3RQ06 GFOD2 PTHR43818:SF8 BCDNA.GH03377 GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000004634.3|UniProtKB=G3SCE9 G3SCE9 MAP1A PTHR13843:SF6 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1A protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;regulation of microtubule-based process#GO:0032886;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;regulation of supramolecular fiber organization#GO:1902903;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;neuron projection development#GO:0031175;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;cell morphogenesis involved in neuron differentiation#GO:0048667;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;dendrite development#GO:0016358;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell body#GO:0044297 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000023732.2|UniProtKB=A0A2I2Y354 A0A2I2Y354 PTHR11240:SF94 RIBONUCLEASE T2 RIBONUCLEASE T2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA catabolic process#GO:0006401 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000007674.3|UniProtKB=G3QXG5 G3QXG5 NICN1 PTHR31239:SF4 NICOLIN 1 NICOLIN-1 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 GORGO|Ensembl=ENSGGOG00000011426.3|UniProtKB=G3R727 G3R727 XDH PTHR11908:SF80 XANTHINE DEHYDROGENASE XANTHINE DEHYDROGENASE_OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;purine-containing compound catabolic process#GO:0072523;purine nucleobase catabolic process#GO:0006145;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Purine metabolism#P02769>Xanthine Oxidase#P03116;Adenine and hypoxanthine salvage pathway#P02723>Xanthine dehydrogenase#P02809 GORGO|Ensembl=ENSGGOG00000008068.3|UniProtKB=G3S6B7 G3S6B7 P2RY6 PTHR24231:SF16 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 6 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000015317.2|UniProtKB=A0A2I2YTV6 A0A2I2YTV6 NAA38 PTHR10701:SF5 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000001150.3|UniProtKB=G3QFQ5 G3QFQ5 INPP5B PTHR11200:SF307 INOSITOL 5-PHOSPHATASE TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 cytosol#GO:0005829;membrane#GO:0016020;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000011914.3|UniProtKB=G3R8B2 G3R8B2 ZIC3 PTHR19818:SF175 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 3 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009357.3|UniProtKB=G3R1R7 G3R1R7 MFN1 PTHR10465:SF2 TRANSMEMBRANE GTPASE FZO1 MITOFUSIN-1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005;organelle localization#GO:0051640;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitochondrion localization#GO:0051646 mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000004078.3|UniProtKB=G3QN93 G3QN93 ADCY3 PTHR45627:SF30 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 3 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 GORGO|Ensembl=ENSGGOG00000006265.3|UniProtKB=A0A2I2Y1T4 A0A2I2Y1T4 BAHCC1 PTHR12505:SF22 PHD FINGER TRANSCRIPTION FACTOR BAH AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000037702.1|UniProtKB=A0A2I2YYI1 A0A2I2YYI1 TRABD2B PTHR31120:SF8 METALLOPROTEASE TIKI METALLOPROTEASE TIKI2 binding#GO:0005488;Wnt-protein binding#GO:0017147;protein binding#GO:0005515 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000001739.3|UniProtKB=G3QH89 G3QH89 TOMM20L PTHR12430:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 TOMM20-LIKE PROTEIN 1 intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;protein transport#GO:0015031;transmembrane transport#GO:0055085;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;mitochondrial transport#GO:0006839;nucleobase-containing compound transport#GO:0015931;protein localization to mitochondrion#GO:0070585 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane translocase complex#GO:0005742;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025050.2|UniProtKB=G3QHX9 G3QHX9 PRAMEF20 PTHR14224:SF93 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 20 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul2-RING ubiquitin ligase complex#GO:0031462;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000023809.2|UniProtKB=G3S4D7 G3S4D7 LGI2 PTHR24367:SF21 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 2 cellular component organization#GO:0016043;cell junction assembly#GO:0034329;synapse assembly#GO:0007416;cell junction organization#GO:0034330;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 GORGO|Ensembl=ENSGGOG00000040931.1|UniProtKB=A0A2I2Z0R1 A0A2I2Z0R1 LPGAT1 PTHR10983:SF2 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED ACYL-COA:LYSOPHOSPHATIDYLGLYCEROL ACYLTRANSFERASE 1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004487.3|UniProtKB=G3QPA7 G3QPA7 LINGO4 PTHR24369:SF178 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000015530.3|UniProtKB=G3RHN0 G3RHN0 RGS9 PTHR45746:SF1 LP21163P REGULATOR OF G PROTEIN SIGNALING 9 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701 plasma membrane#GO:0005886;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>RGS9#P00749;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 GORGO|Ensembl=ENSGGOG00000037890.1|UniProtKB=A0A2I2Y7M1 A0A2I2Y7M1 PTHR13341:SF9 MIR-INTERACTING SAPOSIN-LIKE PROTEIN CANOPY 2 HOMOLOG (ZEBRAFISH) molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of biological process#GO:0050789 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000022072.2|UniProtKB=A0A2I2YDV4 A0A2I2YDV4 CDKN2AIP PTHR16148:SF11 NF-KAPPA-B-REPRESSING FACTOR-RELATED CDKN2A-INTERACTING PROTEIN regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000012001.3|UniProtKB=G3R8J3 G3R8J3 DPPA5 PTHR31368:SF4 DEVELOPMENT PLURPOTENCY-ASSOCIATED PROTEIN 1/5 FAMILY MEMBER DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED 5 PROTEIN RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000041818.1|UniProtKB=A0A2I2YEA5 A0A2I2YEA5 UBE2Z PTHR46116:SF26 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME UBIQUITIN-CONJUGATING ENZYME E2 Z ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012429.3|UniProtKB=G3R9R2 G3R9R2 CCDC180 PTHR21444:SF14 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 GORGO|Ensembl=ENSGGOG00000011167.3|UniProtKB=A0A2I2ZLQ4 A0A2I2ZLQ4 CUL4B PTHR11932:SF66 CULLIN CULLIN-4B protein binding#GO:0005515;structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA damage response#GO:0006974;response to stimulus#GO:0050896;catabolic process#GO:0009056;ribonucleoprotein complex biogenesis#GO:0022613;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;ribosome biogenesis#GO:0042254;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000006836.3|UniProtKB=A0A2I2Y4M2 A0A2I2Y4M2 PHF13 PTHR14571:SF13 HISTONE-LYSINE N-METHYLTRANSFERASE SET-26-RELATED PHD FINGER PROTEIN 13 chromatin binding#GO:0003682;binding#GO:0005488 chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;nuclear division#GO:0000280;organelle fission#GO:0048285;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic cell cycle#GO:0000278 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000002801.4|UniProtKB=G3QK02 G3QK02 CCDC73 PTHR28660:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 73 COILED-COIL DOMAIN-CONTAINING PROTEIN 73 GORGO|Ensembl=ENSGGOG00000011356.3|UniProtKB=G3R6V4 G3R6V4 TASOR PTHR16207:SF1 SET DOMAIN-CONTAINING PROTEIN PROTEIN TASOR binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;intracellular protein localization#GO:0008104;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;macromolecule localization#GO:0033036;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;localization#GO:0051179;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789 chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000010034.3|UniProtKB=G3R3G6 G3R3G6 C1QA PTHR15427:SF26 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 humoral immune response#GO:0006959;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of immune system process#GO:0002684;immune response#GO:0006955;positive regulation of biological process#GO:0048518;complement activation#GO:0006956;activation of immune response#GO:0002253;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;biological regulation#GO:0065007;immune system process#GO:0002376;regulation of immune response#GO:0050776;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015549.3|UniProtKB=A0A2I2Y2S7 A0A2I2Y2S7 RAD17 PTHR12172:SF2 CELL CYCLE CHECKPOINT PROTEIN RAD17 CELL CYCLE CHECKPOINT PROTEIN RAD17 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;cell cycle process#GO:0022402;mitotic DNA replication checkpoint signaling#GO:0033314;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;regulation of mitotic cell cycle phase transition#GO:1901990 membraneless organelle#GO:0043228;site of double-strand break#GO:0035861;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;site of DNA damage#GO:0090734;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000023892.2|UniProtKB=G3S534 G3S534 PTHR11595:SF21 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-DELTA guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000024514.2|UniProtKB=A0A2I2YN15 A0A2I2YN15 MRPL49 PTHR13477:SF0 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49 LARGE RIBOSOMAL SUBUNIT PROTEIN ML49 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001814.3|UniProtKB=G3QHG0 G3QHG0 ILF2 PTHR46447:SF1 INTERLEUKIN ENHANCER-BINDING FACTOR INTERLEUKIN ENHANCER-BINDING FACTOR 2 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;DNA binding#GO:0003677;RNA binding#GO:0003723 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000009529.3|UniProtKB=G3R267 G3R267 LOC101137069 PTHR11380:SF17 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;transcription by RNA polymerase II#GO:0006366;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774 membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000017017.3|UniProtKB=G3RLF9 G3RLF9 NTSR1 PTHR24243:SF9 G-PROTEIN COUPLED RECEPTOR NEUROTENSIN RECEPTOR TYPE 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000002359.3|UniProtKB=A0A2I2ZHP4 A0A2I2ZHP4 POMGNT1 PTHR46396:SF1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000025444.2|UniProtKB=G3SF15 G3SF15 ANKRD7 PTHR24147:SF62 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 7 GORGO|Ensembl=ENSGGOG00000002562.3|UniProtKB=A0A2I2YAR4 A0A2I2YAR4 LCK PTHR24418:SF39 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE LCK binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of immune response#GO:0050776;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;immune response-regulating cell surface receptor signaling pathway#GO:0002768;hemopoiesis#GO:0030097;biological regulation#GO:0065007;cellular developmental process#GO:0048869;developmental process#GO:0032502;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;cell development#GO:0048468;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;regulation of biological process#GO:0050789;mononuclear cell differentiation#GO:1903131;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851;T cell differentiation#GO:0030217;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 T cell activation#P00053>Lck#P01310;Parkinson disease#P00049>Src kinase#P01230 GORGO|Ensembl=ENSGGOG00000042437.1|UniProtKB=A0A2I2ZMK6 A0A2I2ZMK6 RAB3D PTHR47980:SF17 LD44762P RAS-RELATED PROTEIN RAB-3D protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488 exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;presynapse#GO:0098793;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000039546.1|UniProtKB=G3SEV9 G3SEV9 PTHR23411:SF32 TAPASIN T CELL RECEPTOR BETA CONSTANT 2 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;signaling receptor complex#GO:0043235 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>TCR Beta#P01299 GORGO|Ensembl=ENSGGOG00000011550.3|UniProtKB=G3R7D0 G3R7D0 ATP6V1E2 PTHR45715:SF7 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED V-TYPE PROTON ATPASE SUBUNIT E 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810 membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 GORGO|Ensembl=ENSGGOG00000016376.3|UniProtKB=G3RJT8 G3RJT8 FOXP4 PTHR45796:SF7 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P4 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000016135.3|UniProtKB=G3RJ58 G3RJ58 FGFBP1 PTHR15258:SF2 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515;growth factor binding#GO:0019838 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052 GORGO|Ensembl=ENSGGOG00000037609.1|UniProtKB=A0A2I2Z7R6 A0A2I2Z7R6 PTHR31813:SF3 PROLINE-RICH PROTEIN 23B PROLINE-RICH PROTEIN 23D1-RELATED GORGO|Ensembl=ENSGGOG00000002471.3|UniProtKB=G3RQ61 G3RQ61 ITGB8 PTHR10082:SF9 INTEGRIN BETA SUBUNIT INTEGRIN BETA-8 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839 cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell adhesion mediated by integrin#GO:0033627;cell surface receptor signaling pathway#GO:0007166;cell migration#GO:0016477;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987 signaling receptor complex#GO:0043235;cell junction#GO:0030054;integrin complex#GO:0008305;anchoring junction#GO:0070161;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 GORGO|Ensembl=ENSGGOG00000027785.2|UniProtKB=A0A2I2Z0Y4 A0A2I2Z0Y4 PTHR10551:SF9 FASCIN FASCIN-2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000016576.3|UniProtKB=A0A2I2Y909 A0A2I2Y909 CLUAP1 PTHR21547:SF0 CLUSTERIN ASSOCIATED PROTEIN 1 CLUSTERIN-ASSOCIATED PROTEIN 1 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intraciliary transport particle B#GO:0030992;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000006810.3|UniProtKB=G3QVA4 G3QVA4 GNB1 PTHR19850:SF29 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-1 signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020;heterotrimeric G-protein#PC00117;protein-binding activity modulator#PC00095 Nicotine pharmacodynamics pathway#P06587>GNB#P06591;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;GABA-B receptor II signaling#P05731>Gbeta#P05755;Enkephalin release#P05913>G-Protein (s)#P05977;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;PI3 kinase pathway#P00048>Gbetagamma#P01188;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Wnt signaling pathway#P00057>GBeta#P01457;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;CCKR signaling map#P06959>Gbeta/gamma#P07197;Enkephalin release#P05913>G-Protein (i)#P05974;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710 GORGO|Ensembl=ENSGGOG00000010316.3|UniProtKB=A0A2I2Z835 A0A2I2Z835 PTHR46088:SF1 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000022362.2|UniProtKB=G3SCD7 G3SCD7 LYZL2 PTHR11407:SF62 LYSOZYME C LYSOZYME-LIKE PROTEIN 1-RELATED lysozyme activity#GO:0003796;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000042664.1|UniProtKB=A0A2I2YVC4 A0A2I2YVC4 STPG2 PTHR21580:SF64 SHIPPO-1-RELATED SPERM-TAIL PG-RICH REPEAT-CONTAINING PROTEIN 2 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000007320.3|UniProtKB=G3QWJ7 G3QWJ7 PTHR23262:SF50 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-8 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000011069.3|UniProtKB=G3R650 G3R650 PTHR10159:SF109 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 2 catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;tissue development#GO:0009888;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;anatomical structure development#GO:0048856;cell communication#GO:0007154;negative regulation of signal transduction#GO:0009968;endoderm formation#GO:0001706;embryo development#GO:0009790;cellular process#GO:0009987;signal transduction#GO:0007165;endoderm development#GO:0007492;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;regulation of MAPK cascade#GO:0043408;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;gastrulation#GO:0007369;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;formation of primary germ layer#GO:0001704;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000007170.3|UniProtKB=G3QW66 G3QW66 PTHR24411:SF57 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000027095.2|UniProtKB=G3RMA3 G3RMA3 ZNF574 PTHR24409:SF450 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000043719.1|UniProtKB=A0A2I2Z341 A0A2I2Z341 ZNF653 PTHR46179:SF9 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 653 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000002000.3|UniProtKB=G3QHY9 G3QHY9 TNK1 PTHR24418:SF263 TYROSINE-PROTEIN KINASE NON-RECEPTOR TYROSINE-PROTEIN KINASE TNK1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 GORGO|Ensembl=ENSGGOG00000008031.3|UniProtKB=G3QYC2 G3QYC2 COLGALT1 PTHR10730:SF28 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN GALACTOSYLTRANSFERASE 1 galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000027082.2|UniProtKB=G3SG32 G3SG32 LYVE1 PTHR10225:SF2 HYALURONAN RECEPTOR LYMPHATIC VESSEL ENDOTHELIAL HYALURONIC ACID RECEPTOR 1 signaling receptor activity#GO:0038023;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000039185.1|UniProtKB=A0A2I2ZG85 A0A2I2ZG85 CHAC2 PTHR12192:SF2 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2 GORGO|Ensembl=ENSGGOG00000042380.1|UniProtKB=A0A2I2YFQ9 A0A2I2YFQ9 PTHR14907:SF5 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000003772.3|UniProtKB=G3QMG5 G3QMG5 COL8A2 PTHR24023:SF855 COLLAGEN ALPHA COLLAGEN ALPHA-2(VIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000042897.1|UniProtKB=A0A2I2YED7 A0A2I2YED7 RTL1 PTHR15503:SF39 LDOC1 RELATED RETROTRANSPOSON-LIKE PROTEIN 1 muscle structure development#GO:0061061;tissue development#GO:0009888;skeletal muscle tissue development#GO:0007519;animal organ development#GO:0048513;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;placenta development#GO:0001890;muscle organ development#GO:0007517;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;developmental process#GO:0032502;striated muscle tissue development#GO:0014706 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000005223.3|UniProtKB=G3QR76 G3QR76 NRN1 PTHR15902:SF1 NEURITIN-RELATED NEURITIN anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;developmental cell growth#GO:0048588;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;neuron projection extension#GO:1990138;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental growth#GO:0048589;cellular developmental process#GO:0048869;cell growth#GO:0016049 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000009734.3|UniProtKB=G3R2P7 G3R2P7 CHST15 PTHR15723:SF0 CARBOHYDRATE SULFOTRANSFERASE 15 CARBOHYDRATE SULFOTRANSFERASE 15 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;hexose biosynthetic process#GO:0019319;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000016336.3|UniProtKB=A0A2I2YT34 A0A2I2YT34 RNF38 PTHR46171:SF1 GH10160P E3 UBIQUITIN-PROTEIN LIGASE RNF38 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 GORGO|Ensembl=ENSGGOG00000008745.3|UniProtKB=G3R075 G3R075 TIE1 PTHR24416:SF341 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TIE-1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of angiogenesis#GO:0045765;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of angiogenesis#GO:0045766;regulation of anatomical structure morphogenesis#GO:0022603;cell surface receptor signaling pathway#GO:0007166;positive regulation of developmental process#GO:0051094;regulation of vasculature development#GO:1901342;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001413.3|UniProtKB=G3QGE0 G3QGE0 EEF1AKMT3 PTHR14614:SF5 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN EEF1A LYSINE METHYLTRANSFERASE 3 protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;lysine N-methyltransferase activity#GO:0016278 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015599.3|UniProtKB=A0A2I2ZU66 A0A2I2ZU66 PRRT2 PTHR14948:SF20 NG5 PROLINE-RICH TRANSMEMBRANE PROTEIN 2 exocytic process#GO:0140029;regulated exocytosis#GO:0045055;vesicle fusion to plasma membrane#GO:0099500;vesicle organization#GO:0016050;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;export from cell#GO:0140352;signaling#GO:0023052;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;synaptic vesicle membrane organization#GO:0048499;membrane fusion#GO:0061025;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;membrane organization#GO:0061024;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;vesicle fusion#GO:0006906;anterograde trans-synaptic signaling#GO:0098916 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006775.3|UniProtKB=G3QV68 G3QV68 GAD2 PTHR45677:SF11 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 2 lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 GORGO|Ensembl=ENSGGOG00000016411.3|UniProtKB=G3RJV7 G3RJV7 LOC101129533 PTHR23262:SF145 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 1-3 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000016508.3|UniProtKB=G3RK47 G3RK47 TFPT PTHR35084:SF1 TCF3 FUSION PARTNER TCF3 FUSION PARTNER DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 positive regulation of apoptotic process#GO:0043065;apoptotic signaling pathway#GO:0097190;regulation of apoptotic process#GO:0042981;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Ino80 complex#GO:0031011;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228 GORGO|Ensembl=ENSGGOG00000036208.1|UniProtKB=A0A2I2YT04 A0A2I2YT04 PTHR31878:SF0 CHEMOKINE-LIKE PROTEIN TAFA-5-RELATED CHEMOKINE-LIKE PROTEIN TAFA-5 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chemokine#PC00074;cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000006840.3|UniProtKB=G3QVC9 G3QVC9 GALNT1 PTHR11675:SF123 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000038718.1|UniProtKB=G3SH29 G3SH29 KRBOX5 PTHR24381:SF125 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 674 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005929.3|UniProtKB=G3QT01 G3QT01 CKMT2 PTHR11547:SF19 ARGININE OR CREATINE KINASE CREATINE KINASE S-TYPE, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775 biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 GORGO|Ensembl=ENSGGOG00000011011.3|UniProtKB=G3R601 G3R601 HPD PTHR11959:SF12 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000036548.1|UniProtKB=G3R5M2 G3R5M2 GPR25 PTHR24228:SF9 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR C-X-C CHEMOKINE RECEPTOR GPR25 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000014582.3|UniProtKB=G3RF62 G3RF62 ZNF511 PTHR21354:SF0 ZINC FINGER PROTEIN 511 ZINC FINGER PROTEIN 511 GORGO|Ensembl=ENSGGOG00000000472.3|UniProtKB=A0A2I2ZRG1 A0A2I2ZRG1 TPM3 PTHR19269:SF78 TROPOMYOSIN TROPOMYOSIN 3 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin cytoskeleton organization#GO:0030036;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;muscle system process#GO:0003012;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;muscle contraction#GO:0006936;actin filament-based process#GO:0030029 intracellular organelle#GO:0043229;actin filament#GO:0005884;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000022257.2|UniProtKB=G3RSM9 G3RSM9 LOC101152793 PTHR10361:SF29 SODIUM-BILE ACID COTRANSPORTER SODIUM_BILE ACID COTRANSPORTER 5 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic cation transmembrane transporter activity#GO:0008324;bile acid transmembrane transporter activity#GO:0015125;solute:sodium symporter activity#GO:0015370 localization#GO:0051179;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid transport#GO:0006869;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000009159.3|UniProtKB=G3R1A0 G3R1A0 KLHL12 PTHR24412:SF455 KELCH PROTEIN KELCH-LIKE PROTEIN 12 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;cellular localization#GO:0051641;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;proteasomal protein catabolic process#GO:0010498;COPII-coated vesicle budding#GO:0090114;localization#GO:0051179;protein metabolic process#GO:0019538;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;intracellular transport#GO:0046907;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;ubiquitin-dependent protein catabolic process#GO:0006511;membrane organization#GO:0061024 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000043118.1|UniProtKB=A0A2I2ZB50 A0A2I2ZB50 PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000006892.3|UniProtKB=G3QVH5 G3QVH5 PNKD PTHR11935:SF116 BETA LACTAMASE DOMAIN THIOESTERASE PNKD-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013380.3|UniProtKB=G3R9L6 G3R9L6 ASTN1 PTHR16592:SF8 ASTROTACTIN-1-LIKE ASTROTACTIN-1 cell motility#GO:0048870;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;cell migration#GO:0016477;nervous system development#GO:0007399;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;developmental process#GO:0032502 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000027309.2|UniProtKB=G3RQF6 G3RQF6 C1QTNF8 PTHR22923:SF117 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 8 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;regulation of cellular process#GO:0050794;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;positive regulation of cell motility#GO:2000147;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000028590.2|UniProtKB=A0A2I2ZFS5 A0A2I2ZFS5 PTHR12746:SF2 NONSENSE-MEDIATED MRNA DECAY PROTEIN 3 60S RIBOSOMAL EXPORT PROTEIN NMD3 ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488 establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit export from nucleus#GO:0000055;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;organelle localization#GO:0051640;ribosome biogenesis#GO:0042254;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;transport#GO:0006810 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000027205.2|UniProtKB=G3S1D1 G3S1D1 CRY1 PTHR11455:SF16 CRYPTOCHROME CRYPTOCHROME-1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleic acid binding#GO:0003676;deoxyribodipyrimidine photo-lyase activity#GO:0003904;ion binding#GO:0043167;DNA binding#GO:0003677;carbon-carbon lyase activity#GO:0016830;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;photoperiodism#GO:0009648;negative regulation of cellular process#GO:0048523;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of circadian rhythm#GO:0042752;response to radiation#GO:0009314;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;rhythmic process#GO:0048511;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA photolyase#PC00014 Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>cry#G01501;Circadian clock system#P00015>Cry#P00505 GORGO|Ensembl=ENSGGOG00000006373.3|UniProtKB=G3QU39 G3QU39 HFE PTHR16675:SF172 MHC CLASS I-RELATED HEREDITARY HEMOCHROMATOSIS PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of transport#GO:0051049;regulation of localization#GO:0032879;immune system process#GO:0002376;regulation of monoatomic ion transport#GO:0043269;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;response to starvation#GO:0042594;response to nutrient levels#GO:0031667;response to stress#GO:0006950;immune response#GO:0006955;regulation of biological process#GO:0050789 extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000016362.3|UniProtKB=G3RJS6 G3RJS6 PPP1R21 PTHR21448:SF0 SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000040553.1|UniProtKB=A0A2I2YB57 A0A2I2YB57 ZAN PTHR11339:SF374 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED ZONADHESIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000026709.2|UniProtKB=G3RV07 G3RV07 PTHR11890:SF19 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER SINGLE IG IL-1-RELATED RECEPTOR regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007910.3|UniProtKB=G3QY15 G3QY15 FAM83H PTHR16181:SF33 PROTEIN FAM83A-RELATED PROTEIN FAM83H kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 regulation of cell migration#GO:0030334;intracellular protein localization#GO:0008104;positive regulation of locomotion#GO:0040017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of cell migration#GO:0030335;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;organelle organization#GO:0006996;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;intermediate filament-based process#GO:0045103;localization#GO:0051179;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;signaling#GO:0023052;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000041294.1|UniProtKB=A0A2I2YRG9 A0A2I2YRG9 RBM43 PTHR15225:SF8 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN RNA-BINDING PROTEIN 43 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000004243.3|UniProtKB=G3QNP3 G3QNP3 VIPR1 PTHR45620:SF24 PDF RECEPTOR-LIKE PROTEIN-RELATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000024967.2|UniProtKB=A0A2I2ZCE9 A0A2I2ZCE9 C2H3orf33 PTHR28434:SF1 PROTEIN C3ORF33 MITOCHONDRIAL INNER MEMBRANE SUBDOMAIN ORGANIZER 1 GORGO|Ensembl=ENSGGOG00000039170.1|UniProtKB=A0A2I2YHN5 A0A2I2YHN5 PTHR19343:SF15 T CELL RECEPTOR ALPHA VARIABLE 1-2 IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000004975.3|UniProtKB=G3QQK6 G3QQK6 PIGV PTHR12468:SF2 GPI MANNOSYLTRANSFERASE 2 GPI ALPHA-1,6-MANNOSYLTRANSFERASE 2 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 mannosyltransferase complex#GO:0031501;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004427.3|UniProtKB=G3QP59 G3QP59 LRRC2 PTHR48051:SF16 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 2 ISOFORM X1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000043641.1|UniProtKB=A0A2I2YU54 A0A2I2YU54 PTHR12936:SF2 ANAPHASE-PROMOTING COMPLEX 10 ANAPHASE-PROMOTING COMPLEX SUBUNIT 10 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;cell cycle#GO:0007049;primary metabolic process#GO:0044238;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538 organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000040605.1|UniProtKB=G3SDS6 G3SDS6 PTHR23266:SF262 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-69-RELATED binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000316.2|UniProtKB=G3QDJ0 G3QDJ0 PSPN PTHR12173:SF8 GDNF SUBFAMILY OF TGF-BETA FAMILY PERSEPHIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 neurotrophic factor#PC00163;intercellular signal molecule#PC00207;growth factor#PC00112 GORGO|Ensembl=ENSGGOG00000006570.3|UniProtKB=G3QUM4 G3QUM4 FAM110D PTHR14758:SF3 AGAP005440-PA PROTEIN FAM110D GORGO|Ensembl=ENSGGOG00000003469.3|UniProtKB=A0A2I2Z9G0 A0A2I2Z9G0 LOC101146324 PTHR11732:SF165 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER C1-RELATED organic acid binding#GO:0043177;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;fatty acid metabolic process#GO:0006631;secondary metabolic process#GO:0019748;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;icosanoid metabolic process#GO:0006690;prostaglandin metabolic process#GO:0006693;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;regulation of biological quality#GO:0065008;regulation of hormone levels#GO:0010817;monocarboxylic acid metabolic process#GO:0032787;ketone metabolic process#GO:0042180;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016395.3|UniProtKB=G3RJU6 G3RJU6 PTHR23262:SF218 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-10-RELATED structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000038601.1|UniProtKB=A0A2I2Z7Q6 A0A2I2Z7Q6 PTHR23232:SF112 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 726 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005281.3|UniProtKB=G3QRD2 G3QRD2 TMCO4 PTHR17920:SF3 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000011254.3|UniProtKB=A0A2I2Z261 A0A2I2Z261 PTHR11753:SF6 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-2 COMPLEX SUBUNIT SIGMA cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000015813.3|UniProtKB=A0A2I2YN86 A0A2I2YN86 PTHR24078:SF568 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 1 Hsp70 protein binding#GO:0030544;heat shock protein binding#GO:0031072;transcription coregulator activity#GO:0003712;protein-folding chaperone binding#GO:0051087;transcription corepressor activity#GO:0003714;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488 cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;gene expression#GO:0010467;protein maturation#GO:0051604;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;metabolic process#GO:0008152;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;protein folding#GO:0006457;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000041228.1|UniProtKB=A0A2I2Y468 A0A2I2Y468 PTHR11071:SF453 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000015075.3|UniProtKB=G3RGG7 G3RGG7 MLPH PTHR14555:SF1 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED MELANOPHILIN actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;myosin binding#GO:0017022;protein binding#GO:0005515 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944 myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000037345.1|UniProtKB=A0A2I2Z9B3 A0A2I2Z9B3 AVPR1A PTHR24241:SF17 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V1A RECEPTOR signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;circulatory system process#GO:0003013;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;response to chemical#GO:0042221;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;response to hormone#GO:0009725;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002051.3|UniProtKB=A0A2I2Y7Q5 A0A2I2Y7Q5 PTHR23113:SF174 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;multicellular organismal process#GO:0032501;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of response to stimulus#GO:0048584;cell activation#GO:0001775;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;cell communication#GO:0007154;positive regulation of lymphocyte mediated immunity#GO:0002708;cellular response to stimulus#GO:0051716;regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated immunity#GO:0002703;leukocyte activation#GO:0045321;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;B cell activation#GO:0042113;positive regulation of response to external stimulus#GO:0032103;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;intracellular signaling cassette#GO:0141124;regulation of response to external stimulus#GO:0032101;lymphocyte activation#GO:0046649;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of biological process#GO:0050789;T cell activation#GO:0042110;signaling#GO:0023052;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 GORGO|Ensembl=ENSGGOG00000002882.3|UniProtKB=A0A2I2Y2W4 A0A2I2Y2W4 TUBGCP4 PTHR19302:SF27 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 4 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;organelle assembly#GO:0070925 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000011627.3|UniProtKB=G3R7J7 G3R7J7 LOC101154556 PTHR21320:SF8 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000001025.2|UniProtKB=G3QFD9 G3QFD9 CLDN17 PTHR12002:SF75 CLAUDIN CLAUDIN-17 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 establishment of localization#GO:0051234;paracellular transport#GO:0160184;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329 cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000013020.3|UniProtKB=G3RB61 G3RB61 GEM PTHR45775:SF4 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN GEM channel regulator activity#GO:0016247;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166;ion channel regulator activity#GO:0099106;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;calcium channel regulator activity#GO:0005246;ribonucleotide binding#GO:0032553 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000001132.3|UniProtKB=G3QFN9 G3QFN9 LAMTOR3 PTHR13378:SF3 REGULATOR COMPLEX PROTEIN LAMTOR3 RAGULATOR COMPLEX PROTEIN LAMTOR3 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;response to acid chemical#GO:0001101;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of TORC1 signaling#GO:1904263;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432 vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026476.2|UniProtKB=G3S4W0 G3S4W0 PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A CONSERVED DOMAIN-CONTAINING PROTEIN-RELATED cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi stack#GO:0005795;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;cis-Golgi network#GO:0005801;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasm#GO:0005737;Golgi cis cisterna#GO:0000137;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013993.3|UniProtKB=G3S3N4 G3S3N4 UROC1 PTHR12216:SF3 UROCANATE HYDRATASE UROCANATE HYDRATASE hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 hydratase#PC00120 GORGO|Ensembl=ENSGGOG00000005089.3|UniProtKB=G3QQW3 G3QQW3 KLHDC9 PTHR47196:SF1 KELCH DOMAIN-CONTAINING PROTEIN 9 KELCH DOMAIN-CONTAINING PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;cyclin binding#GO:0030332 GORGO|Ensembl=ENSGGOG00000001447.3|UniProtKB=G3QGH2 G3QGH2 THSD4 PTHR13723:SF16 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 4 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Gene=CHRM3|UniProtKB=Q9N2A3 Q9N2A3 CHRM3 PTHR24248:SF153 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>mAChR1/3#P01069;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000001829.3|UniProtKB=A0A2I2YUE4 A0A2I2YUE4 RNF7 PTHR11210:SF60 RING BOX RING-BOX PROTEIN 2 binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;Cul5-RING ubiquitin ligase complex#GO:0031466;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000004319.3|UniProtKB=A0A2I2YPN4 A0A2I2YPN4 DIP2B PTHR22754:SF38 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG B catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of growth#GO:0040008;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;cellular component organization#GO:0016043;regulation of neurogenesis#GO:0050767;negative regulation of cellular component organization#GO:0051129;regulation of developmental process#GO:0050793;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological quality#GO:0065008;regulation of cell size#GO:0008361;regulation of nervous system development#GO:0051960;regulation of neuron projection development#GO:0010975;regulation of cell development#GO:0060284;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;negative regulation of cell growth#GO:0030308;regulation of cell growth#GO:0001558;regulation of cell differentiation#GO:0045595;regulation of anatomical structure size#GO:0090066;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of axonogenesis#GO:0050770;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000006567.3|UniProtKB=G3QUM0 G3QUM0 C1H1orf198 PTHR34394:SF1 SIMILAR TO RIKEN CDNA 2310022B05 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 198 GORGO|Ensembl=ENSGGOG00000008905.3|UniProtKB=G3R0L7 G3R0L7 SMR3B PTHR14179:SF13 SMR1-RELATED SUBMAXILLARY GLAND ANDROGEN-REGULATED PROTEIN 3B protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000001745.3|UniProtKB=A0A2I2ZWE4 A0A2I2ZWE4 DIAPH3 PTHR45691:SF9 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 3 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 GORGO|Ensembl=ENSGGOG00000014647.2|UniProtKB=G3RFC0 G3RFC0 OR6P1 PTHR24242:SF426 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000022266.2|UniProtKB=G3S5M2 G3S5M2 LOC101123674 PTHR22306:SF2 CHROMOSOME 7 OPEN READING FRAME 50 PROTEIN CHOLESIN GORGO|Ensembl=ENSGGOG00000024120.2|UniProtKB=G3SBJ0 G3SBJ0 MAML2 PTHR15692:SF9 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 2 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000022223.2|UniProtKB=G3RS12 G3RS12 BZW2 PTHR14208:SF7 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN EIF5-MIMIC PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000025006.2|UniProtKB=G3RQW7 G3RQW7 TRIM32 PTHR25464:SF3 TRIPARTITE MOTIF-CONTAINING PROTEIN 2-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE TRIM32 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;positive regulation of cytokine-mediated signaling pathway#GO:0001961;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;response to stimulus#GO:0050896;regulation of cytokine-mediated signaling pathway#GO:0001959;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of response to cytokine stimulus#GO:0060759;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;cellular response to amino acid starvation#GO:0034198 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000003611.3|UniProtKB=A0A2I2YMQ0 A0A2I2YMQ0 SNX16 PTHR22999:SF43 PX SERINE/THREONINE KINASE PXK SORTING NEXIN-16 small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;ion binding#GO:0043167 macromolecule metabolic process#GO:0043170;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;metabolic process#GO:0008152;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000034985.2|UniProtKB=G3SKK6 G3SKK6 GTPBP10 PTHR11702:SF43 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED GTP-BINDING PROTEIN 10 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009509.3|UniProtKB=G3R268 G3R268 ITGB4 PTHR10082:SF42 INTEGRIN BETA SUBUNIT INTEGRIN BETA-4 cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;signaling#GO:0023052;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;signal transduction#GO:0007165;cell migration#GO:0016477;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 GORGO|Ensembl=ENSGGOG00000000185.4|UniProtKB=G3QD72 G3QD72 C10H12orf50 PTHR15725:SF1 ZN-FINGER, C-X8-C-X5-C-X3-H TYPE-CONTAINING RIKEN CDNA 1700017N19 GENE RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000002813.3|UniProtKB=G3QK10 G3QK10 SYDE2 PTHR46150:SF1 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN SYDE2 GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of Ras protein signal transduction#GO:0046578;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cell migration#GO:0016477;cell motility#GO:0048870 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000009837.3|UniProtKB=A0A2I2ZR73 A0A2I2ZR73 ME3 PTHR23406:SF20 MALIC ENZYME-RELATED NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000023567.2|UniProtKB=G3SFI4 G3SFI4 LARP7 PTHR22792:SF159 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 7 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000016273.3|UniProtKB=G3RJI3 G3RJI3 SDHB PTHR11921:SF47 SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000022650.2|UniProtKB=G3SI94 G3SI94 OR11H4 PTHR24242:SF381 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H4 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000004180.3|UniProtKB=G3S228 G3S228 ZNF184 PTHR24406:SF11 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED DNA-BINDING PROTEIN REPIN1 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011281.3|UniProtKB=G3RMP9 G3RMP9 GFRA3 PTHR10269:SF15 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003095.3|UniProtKB=G3QKR2 G3QKR2 ZNF566 PTHR23226:SF412 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000043325.1|UniProtKB=A0A2I2Z0Y6 A0A2I2Z0Y6 SCGB1C1 PTHR10136:SF8 SECRETOGLOBIN FAMILY 1 MEMBER SECRETOGLOBIN FAMILY 1C MEMBER 1-RELATED cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000001873.3|UniProtKB=A0A2I2Z3T1 A0A2I2Z3T1 PPP2R2B PTHR11871:SF1 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B BETA ISOFORM molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 cytosol#GO:0005829;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629 GORGO|Ensembl=ENSGGOG00000011634.3|UniProtKB=G3R7K8 G3R7K8 THAP9 PTHR10725:SF82 THAP DOMAIN-CONTAINING PROTEIN 9 DNA TRANSPOSASE THAP9 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;DNA binding#GO:0003677 macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 GORGO|Ensembl=ENSGGOG00000043636.1|UniProtKB=A0A2I2ZQ98 A0A2I2ZQ98 PTHR13396:SF4 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY-INTERACTING PROTEIN 2 regulation of protein modification process#GO:0031399;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of protein ubiquitination#GO:0031396;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000001855.3|UniProtKB=G3QHJ9 G3QHJ9 SCARA5 PTHR19331:SF482 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CLASS A MEMBER 5 cargo receptor activity#GO:0038024 intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;endocytosis#GO:0006897;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000013877.3|UniProtKB=G3RDD4 G3RDD4 PHAX PTHR13135:SF0 CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-26 PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014818.3|UniProtKB=A0A2I2ZC02 A0A2I2ZC02 MAN2C1 PTHR46017:SF1 ALPHA-MANNOSIDASE 2C1 ALPHA-MANNOSIDASE 2C1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000004295.3|UniProtKB=G3QNT6 G3QNT6 NEUROD4 PTHR19290:SF86 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;sensory system development#GO:0048880;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;camera-type eye development#GO:0043010;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000002404.3|UniProtKB=G3QIZ1 G3QIZ1 SBK2 PTHR24359:SF34 SERINE/THREONINE-PROTEIN KINASE SBK1 SERINE_THREONINE-PROTEIN KINASE SBK2 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002046.3|UniProtKB=G3QI25 G3QI25 PFKFB1 PTHR10606:SF15 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 1 hydrolase activity#GO:0016787;phosphotransferase activity, alcohol group as acceptor#GO:0016773;sugar-phosphatase activity#GO:0050308;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740 phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829 hydrolase#PC00121;carbohydrate phosphatase#PC00066;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000023143.2|UniProtKB=G3RPA2 G3RPA2 PTHR46315:SF2 SPERMINE SYNTHASE SPERMINE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;polyamine biosynthetic process#GO:0006596 GORGO|Ensembl=ENSGGOG00000042292.1|UniProtKB=A0A2I2Y529 A0A2I2Y529 ZNF853 PTHR16515:SF20 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 12 protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001013.3|UniProtKB=G3QFC9 G3QFC9 NCF2 PTHR15175:SF3 NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2 NEUTROPHIL CYTOSOL FACTOR 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;superoxide metabolic process#GO:0006801 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000013379.3|UniProtKB=G3SJK5 G3SJK5 OAZ2 PTHR10279:SF6 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 2 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000007703.4|UniProtKB=G3QXJ3 G3QXJ3 ERP44 PTHR46295:SF1 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000010877.3|UniProtKB=G3R5M1 G3R5M1 LOC101139491 PTHR26453:SF161 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T29-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000038737.1|UniProtKB=G3RPQ8 G3RPQ8 PTHR17453:SF2 SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein targeting#GO:0006605;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein targeting to ER#GO:0045047;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular component assembly#GO:0022607;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002544.3|UniProtKB=G3S952 G3S952 SCCPDH PTHR12286:SF5 SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE lipid metabolic process#GO:0006629;metabolic process#GO:0008152;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000006191.3|UniProtKB=G3QTM6 G3QTM6 LOC101131397 PTHR14787:SF2 C10ORF188 FAMILY MEMBER SUBFAMILY NOT NAMED ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000022581.2|UniProtKB=G3RSX2 G3RSX2 IQCF3 PTHR21633:SF5 IQ MOTIF CONTAINING F IQ DOMAIN-CONTAINING PROTEIN F3 GORGO|Ensembl=ENSGGOG00000013944.3|UniProtKB=G3RDJ3 G3RDJ3 NPB PTHR28553:SF1 NEUROPEPTIDE B NEUROPEPTIDE B binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 G protein-coupled receptor signaling pathway#GO:0007186;feeding behavior#GO:0007631;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794 GORGO|Ensembl=ENSGGOG00000013732.3|UniProtKB=G3RCZ8 G3RCZ8 OR6M1 PTHR26454:SF51 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6M1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012772.3|UniProtKB=G3RAI5 G3RAI5 PLA2G12B PTHR12824:SF2 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GROUP XIIB SECRETORY PHOSPHOLIPASE A2-LIKE PROTEIN chemical homeostasis#GO:0048878;lipid homeostasis#GO:0055088;triglyceride homeostasis#GO:0070328;homeostatic process#GO:0042592;cholesterol homeostasis#GO:0042632 hydrolase#PC00121;lipase#PC00143;phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000006319.3|UniProtKB=A0A2I2Y8Z4 A0A2I2Y8Z4 ARHGAP19 PTHR14963:SF7 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 19 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000000127.3|UniProtKB=A0A2I2ZPL6 A0A2I2ZPL6 GAPDHS PTHR10836:SF79 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, TESTIS-SPECIFIC oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891 ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810 GORGO|Ensembl=ENSGGOG00000006958.3|UniProtKB=G3QVN7 G3QVN7 SH3TC2 PTHR22647:SF2 SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000774.3|UniProtKB=G3S5B8 G3S5B8 AKAP13 PTHR13944:SF18 AGAP007712-PA A-KINASE ANCHOR PROTEIN 13 molecular adaptor activity#GO:0060090;protein complex scaffold activity#GO:0140378;MAP kinase scaffold activity#GO:0005078;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;structural molecule activity#GO:0005198;guanyl-nucleotide exchange factor activity#GO:0005085;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;enzyme regulator activity#GO:0030234 regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;intracellular signaling cassette#GO:0141124;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of Rho protein signal transduction#GO:0035023;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 actin cytoskeleton#GO:0015629;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000039489.1|UniProtKB=A0A2I2ZGV8 A0A2I2ZGV8 PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993 heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;chromosome organization#GO:0051276;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006853.3|UniProtKB=A0A2I2YZK2 A0A2I2YZK2 LHX9 PTHR24208:SF95 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX9 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;neuron differentiation#GO:0030182 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000040063.1|UniProtKB=G3RNS0 G3RNS0 LOC134758712 PTHR12461:SF99 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7 hydrolase activity#GO:0016787;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010469.3|UniProtKB=G3RXT3 G3RXT3 MAPK4 PTHR24055:SF25 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell surface receptor signaling pathway#GO:0007166;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099 GORGO|Ensembl=ENSGGOG00000025819.2|UniProtKB=A0A2I2YJU5 A0A2I2YJU5 PPT1 PTHR11247:SF81 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 PALMITOYL-PROTEIN THIOESTERASE 1 hydrolase activity#GO:0016787;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 nervous system development#GO:0007399;multicellular organismal process#GO:0032501;endocytosis#GO:0006897;system development#GO:0048731;localization#GO:0051179;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;import into cell#GO:0098657;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;animal gross anatomical part developmental process#GO:0160108 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000024236.2|UniProtKB=A0A2I2ZRN2 A0A2I2ZRN2 PTHR47140:SF1 MAP3K7 C-TERMINAL-LIKE PROTEIN MAP3K7 C-TERMINAL-LIKE PROTEIN Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TAK#P01285;Ras Pathway#P04393>TAK#P04575 GORGO|Ensembl=ENSGGOG00000000501.3|UniProtKB=G3S1X9 G3S1X9 BCL2L12 PTHR14965:SF2 SI:CH73-248E21.1 BCL-2-LIKE PROTEIN 12 negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135;negative regulation of programmed cell death#GO:0043069;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003930.3|UniProtKB=G3RUI6 G3RUI6 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E10-RELATED GORGO|Ensembl=ENSGGOG00000016951.3|UniProtKB=Q0MQH6 Q0MQH6 NDUFS6 PTHR13156:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;organelle membrane#GO:0031090;oxidoreductase complex#GO:1990204;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000004818.3|UniProtKB=G3QQ64 G3QQ64 RPRD2 PTHR12460:SF40 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 2 RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000007858.3|UniProtKB=G3QXX7 G3QXX7 ADGRE1 PTHR12011:SF449 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001079.3|UniProtKB=A0A2I2Z4A2 A0A2I2Z4A2 UBE2Q2 PTHR24068:SF456 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 Q2 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000022856.2|UniProtKB=A0A2I2YMG4 A0A2I2YMG4 NECTIN4 PTHR23277:SF11 NECTIN-RELATED NECTIN-4 protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000013853.4|UniProtKB=A0A2I2ZN58 A0A2I2ZN58 OSBPL10 PTHR10972:SF47 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 10 steroid binding#GO:0005496;cholesterol binding#GO:0015485;lipid binding#GO:0008289;alcohol binding#GO:0043178;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000027954.2|UniProtKB=A0A2I2ZI67 A0A2I2ZI67 LOC109023382 PTHR46595:SF6 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016727.2|UniProtKB=G3RKN9 G3RKN9 LOC101150945 PTHR16471:SF0 CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN-LIKE PROTEIN CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN-LIKE PROTEIN GORGO|Ensembl=ENSGGOG00000027123.3|UniProtKB=G3SEF4 G3SEF4 ATP8A1 PTHR24092:SF221 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IA intramembrane lipid carrier activity#GO:0140303;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657 cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000015855.3|UniProtKB=G3RIG4 G3RIG4 CEL PTHR43903:SF1 NEUROLIGIN BILE SALT-ACTIVATED LIPASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;carboxylic ester hydrolase activity#GO:0052689;triacylglycerol lipase activity#GO:0004806;signaling receptor binding#GO:0005102;lipase activity#GO:0016298;binding#GO:0005488;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;protein binding#GO:0005515 cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;secretion#GO:0046903;system development#GO:0048731;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;catabolic process#GO:0009056;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;postsynapse organization#GO:0099173;regulation of cell communication#GO:0010646;synaptic vesicle endocytosis#GO:0048488;sphingolipid catabolic process#GO:0030149;chemical synaptic transmission#GO:0007268;primary metabolic process#GO:0044238;establishment of localization#GO:0051234;system process#GO:0003008;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;lipid metabolic process#GO:0006629;transport#GO:0006810;digestion#GO:0007586;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;ceramide metabolic process#GO:0006672;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;synapse assembly#GO:0007416;regulation of body fluid levels#GO:0050878;endocytosis#GO:0006897;signaling#GO:0023052;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;lipid catabolic process#GO:0016042;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;cell surface#GO:0009986;synapse#GO:0045202;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000002798.3|UniProtKB=G3QJZ5 G3QJZ5 PWWP3A PTHR31333:SF4 PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3 FAMILY MEMBER PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3A binding#GO:0005488;chromatin binding#GO:0003682;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;cellular process#GO:0009987;response to stress#GO:0006950;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000011751.3|UniProtKB=G3R7W0 G3R7W0 FAM89B PTHR46949:SF2 LEUCINE REPEAT ADAPTER PROTEIN 25 LEUCINE REPEAT ADAPTER PROTEIN 25 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 regulation of cell motility#GO:2000145;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;establishment or maintenance of cell polarity#GO:0007163;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of cell motility#GO:2000147;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;positive regulation of locomotion#GO:0040017;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;negative regulation of signal transduction#GO:0009968;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of cell migration#GO:0030335 lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cell leading edge#GO:0031252 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000024298.2|UniProtKB=G3QHZ4 G3QHZ4 LOC101138466 PTHR14224:SF2 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 17 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000024981.2|UniProtKB=G3RYC0 G3RYC0 SAXO1 PTHR31516:SF9 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoplasmic microtubule#GO:0005881;axoneme#GO:0005930;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000000666.3|UniProtKB=G3QEG1 G3QEG1 APOA5 PTHR18976:SF13 APOLIPOPROTEIN APOLIPOPROTEIN A-V molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;binding#GO:0005488;molecular function activator activity#GO:0140677;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;enzyme regulator activity#GO:0030234;sterol transfer activity#GO:0120015;transporter activity#GO:0005215;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;molecular function regulator activity#GO:0098772;cholesterol transfer activity#GO:0120020 primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;secondary alcohol metabolic process#GO:1902652;homeostatic process#GO:0042592;small molecule metabolic process#GO:0044281;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;cholesterol efflux#GO:0033344;cellular process#GO:0009987;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;phospholipid transport#GO:0015914;steroid metabolic process#GO:0008202;lipid transport#GO:0006869;transport#GO:0006810;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;establishment of localization#GO:0051234;sterol transport#GO:0015918;sterol metabolic process#GO:0016125 lipoprotein particle#GO:1990777;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;high-density lipoprotein particle#GO:0034364;plasma lipoprotein particle#GO:0034358;membrane-bounded organelle#GO:0043227;very-low-density lipoprotein particle#GO:0034361;vesicle#GO:0031982;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000002684.3|UniProtKB=G3QJP5 G3QJP5 CFAP36 PTHR21532:SF0 PHOSPHODIESTERASE HL CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36 ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;ciliary base#GO:0097546;membraneless organelle#GO:0043228;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000008907.3|UniProtKB=G3R0M3 G3R0M3 FGD3 PTHR12673:SF14 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 3 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 filopodium assembly#GO:0046847;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000012244.3|UniProtKB=G3R962 G3R962 ZNF33B PTHR24377:SF1026 IP01015P-RELATED ZINC FINGER PROTEIN 33B RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000041059.1|UniProtKB=A0A2I2YSP4 A0A2I2YSP4 PTHR19212:SF7 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LRR BINDING FLII INTERACTING PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000042118.1|UniProtKB=A0A2I2YCQ7 A0A2I2YCQ7 DDIT4L PTHR12478:SF17 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 DNA DAMAGE-INDUCIBLE TRANSCRIPT 4-LIKE PROTEIN regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell death#GO:0008219;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;apoptotic process#GO:0006915;programmed cell death#GO:0012501 GORGO|Ensembl=ENSGGOG00000016414.3|UniProtKB=G3RJW4 G3RJW4 HDHD2 PTHR19288:SF46 4-NITROPHENYLPHOSPHATASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000010672.3|UniProtKB=G3R540 G3R540 ADRA1D PTHR24248:SF14 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1D ADRENERGIC RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;system process#GO:0003008;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000026435.2|UniProtKB=G3RWY9 G3RWY9 OR9K2 PTHR26452:SF318 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9K2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000000361.4|UniProtKB=A0A2I2YWL3 A0A2I2YWL3 CSMD1 PTHR45656:SF3 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 1 developmental process involved in reproduction#GO:0003006;multi-multicellular organism process#GO:0044706;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;animal organ morphogenesis#GO:0009887;reproductive process#GO:0022414;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;multicellular organismal reproductive process#GO:0048609;morphogenesis of a branching structure#GO:0001763;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelium development#GO:0060429;tube development#GO:0035295;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;morphogenesis of an epithelium#GO:0002009 GORGO|Ensembl=ENSGGOG00000015484.3|UniProtKB=G3RHI5 G3RHI5 SINHCAF PTHR13422:SF18 SIN3-HDAC COMPLEX-ASSOCIATED FACTOR SIN3-HDAC COMPLEX-ASSOCIATED FACTOR negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of locomotion#GO:0040012;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822 GORGO|Ensembl=ENSGGOG00000017029.3|UniProtKB=G3RLH3 G3RLH3 CASQ2 PTHR10033:SF15 CALSEQUESTRIN CALSEQUESTRIN-2 calcium ion binding#GO:0005509;molecular sequestering activity#GO:0140313;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 regulation of muscle contraction#GO:0006937;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of muscle system process#GO:0090257;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of heart contraction#GO:0008016;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;regulation of transport#GO:0051049;regulation of localization#GO:0032879;calcium-mediated signaling#GO:0019722;regulation of release of sequestered calcium ion into cytosol#GO:0051279;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239 I band#GO:0031674;endoplasmic reticulum#GO:0005783;sarcomere#GO:0030017;membraneless organelle#GO:0043228;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;contractile muscle fiber#GO:0043292;sarcoplasmic reticulum#GO:0016529;Z disc#GO:0030018;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;myofibril#GO:0030016;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000007303.3|UniProtKB=A0A2I2Y1K2 A0A2I2Y1K2 TRIM2 PTHR24104:SF58 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Alzheimer disease-presenilin pathway#P00004>HAC1#P00131 GORGO|Ensembl=ENSGGOG00000000016.3|UniProtKB=G3QCS1 G3QCS1 B3GNT6 PTHR11214:SF382 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE ACETYLGALACTOSAMINYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 biosynthetic process#GO:0009058;aminoglycan biosynthetic process#GO:0006023;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000002286.3|UniProtKB=G3QIN6 G3QIN6 LOC101137992 PTHR11736:SF11 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN D2 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010490.3|UniProtKB=A0A2I2Y9A3 A0A2I2Y9A3 CTNNA2 PTHR18914:SF23 ALPHA CATENIN CATENIN ALPHA-2 protein-containing complex binding#GO:0044877;beta-catenin binding#GO:0008013;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;cell migration#GO:0016477;cell motility#GO:0048870 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;anchoring junction#GO:0070161;adherens junction#GO:0005912 non-motor actin binding protein#PC00165 Wnt signaling pathway#P00057>alpha-catenin#P01471;Cadherin signaling pathway#P00012>alpha-catenin#P00467;Alzheimer disease-presenilin pathway#P00004>alpha-catenin#P00133 GORGO|Ensembl=ENSGGOG00000004904.3|UniProtKB=G3QQF4 G3QQF4 UTP20 PTHR17695:SF11 SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000016014.3|UniProtKB=G3RIV6 G3RIV6 USP50 PTHR21646:SF11 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 50 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of innate immune response#GO:0045088;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;positive regulation of response to external stimulus#GO:0032103;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosome organization#GO:0007032;positive regulation of cellular component biogenesis#GO:0044089;regulation of response to external stimulus#GO:0032101;positive regulation of Wnt signaling pathway#GO:0030177;intracellular signaling cassette#GO:0141124;endomembrane system organization#GO:0010256;positive regulation of immune system process#GO:0002684;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;regulation of canonical Wnt signaling pathway#GO:0060828;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of protein stability#GO:0031647;positive regulation of biological process#GO:0048518 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;postsynaptic density#GO:0014069;cytoplasm#GO:0005737;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;cytosol#GO:0005829;postsynapse#GO:0098794;midbody#GO:0030496 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000000020.3|UniProtKB=G3QCS4 G3QCS4 GAB1 PTHR45960:SF5 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Grb2#P01148;EGF receptor signaling pathway#P00018>Gab#P00563 GORGO|Ensembl=ENSGGOG00000009882.3|UniProtKB=G3S8S9 G3S8S9 SMARCA4 PTHR10799:SF76 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 4 ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000000709.3|UniProtKB=G3QEK1 G3QEK1 RNF207 PTHR22635:SF0 RING FINGER PROTEIN 207 RING FINGER PROTEIN 207 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;transmembrane transporter binding#GO:0044325;heat shock protein binding#GO:0031072;protein binding#GO:0005515;Hsp70 protein binding#GO:0030544 regulation of anatomical structure morphogenesis#GO:0022603;regulation of system process#GO:0044057;regulation of muscle contraction#GO:0006937;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010397.3|UniProtKB=G3R4E6 G3R4E6 KIF26B PTHR21608:SF8 KINESIN-LIKE PROTEIN CG14535 KINESIN-LIKE PROTEIN KIF26B protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;tube morphogenesis#GO:0035239;regulation of cell motility#GO:2000145;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;system development#GO:0048731;developmental growth involved in morphogenesis#GO:0060560;animal gross anatomical part developmental process#GO:0160108;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;kidney development#GO:0001822;renal system development#GO:0072001;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental growth#GO:0048589;anatomical structure formation involved in morphogenesis#GO:0048646;morphogenesis of an epithelium#GO:0002009;regulation of neuron migration#GO:2001222;developmental process#GO:0032502;regulation of cell migration#GO:0030334;growth#GO:0040007 GORGO|Ensembl=ENSGGOG00000004644.3|UniProtKB=G3QPQ4 G3QPQ4 RBM28 PTHR48039:SF7 RNA-BINDING MOTIF PROTEIN 14B RNA-BINDING PROTEIN 28 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000009006.3|UniProtKB=A0A2I2YE80 A0A2I2YE80 NIPAL1 PTHR12570:SF13 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MAGNESIUM TRANSPORTER NIPA3 monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;magnesium ion transport#GO:0015693;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000001354.3|UniProtKB=A0A2I2Z6R0 A0A2I2Z6R0 ODF2 PTHR23162:SF8 OUTER DENSE FIBER OF SPERM TAILS 2 OUTER DENSE FIBER PROTEIN 2 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection assembly#GO:0060491;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of organelle organization#GO:0033043;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000000831.3|UniProtKB=G3QEW5 G3QEW5 PTHR21713:SF1 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NAC-ALPHA DOMAIN-CONTAINING PROTEIN 1 protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000010196.3|UniProtKB=G3R3W3 G3R3W3 PRRX1 PTHR46385:SF1 PAIRED MESODERM HOMEOBOX PROTEIN 1-RELATED PAIRED MESODERM HOMEOBOX PROTEIN 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000036808.1|UniProtKB=A0A2I2YGF5 A0A2I2YGF5 PTHR10064:SF17 60S RIBOSOMAL PROTEIN L22 RPL22 nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012015.3|UniProtKB=G3R8L3 G3R8L3 DOC2A PTHR45729:SF1 RABPHILIN, ISOFORM A DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN ALPHA positive regulation of cellular process#GO:0048522;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;regulation of exocytosis#GO:0017157;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;positive regulation of vesicle fusion#GO:0031340;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;export from cell#GO:0140352;positive regulation of cellular component organization#GO:0051130;positive regulation of secretion#GO:0051047;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940 cytoplasm#GO:0005737;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;presynapse#GO:0098793;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 GORGO|Ensembl=ENSGGOG00000008027.3|UniProtKB=G3QYC6 G3QYC6 CAPN2 PTHR10183:SF268 CALPAIN CALPAIN-2 CATALYTIC SUBUNIT catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000007143.4|UniProtKB=G3QW47 G3QW47 MYO3B PTHR46256:SF1 AGAP011099-PA MYOSIN-IIIB transferase activity, transferring phosphorus-containing groups#GO:0016772;macromolecular conformation isomerase activity#GO:0120543;kinase activity#GO:0016301;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;transferase activity#GO:0016740;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;catalytic activity, acting on a protein#GO:0140096;ATP-dependent activity#GO:0140657;protein serine/threonine kinase activity#GO:0004674;polypeptide conformation or assembly isomerase activity#GO:0120544;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of filopodium assembly#GO:0051489;system process#GO:0003008;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cell projection assembly#GO:0060491;positive regulation of cell projection organization#GO:0031346;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of cellular component organization#GO:0051128;sensory perception of sound#GO:0007605;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nervous system process#GO:0050877;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832 intracellular organelle#GO:0043229;photoreceptor inner segment#GO:0001917;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;stereocilium#GO:0032420;membraneless organelle#GO:0043228;neuron projection#GO:0043005;intracellular membraneless organelle#GO:0043232 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 GORGO|Ensembl=ENSGGOG00000015307.3|UniProtKB=G3RH20 G3RH20 KDM6B PTHR14017:SF5 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 6B histone demethylase activity#GO:0032452;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;chromatin DNA binding#GO:0031490;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;dioxygenase activity#GO:0051213;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;multicellular organismal process#GO:0032501;heart development#GO:0007507;biological regulation#GO:0065007;developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731 intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000005031.3|UniProtKB=G3QQQ8 G3QQQ8 SNAPC1 PTHR15131:SF3 SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1 DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolic process#GO:0016070;snRNA transcription by RNA polymerase III#GO:0042796;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA transcription#GO:0009301;transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000016753.3|UniProtKB=G3RKS4 G3RKS4 UBAP2L PTHR16308:SF18 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER UBIQUITIN-ASSOCIATED PROTEIN 2-LIKE organelle assembly#GO:0070925;homeostasis of number of cells#GO:0048872;cellular component organization or biogenesis#GO:0071840;multicellular organismal-level homeostasis#GO:0048871;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cytoplasmic stress granule assembly#GO:0034063;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;homeostatic process#GO:0042592 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000008024.3|UniProtKB=G3QYB5 G3QYB5 CFAP126 PTHR34639:SF1 PROTEIN FLATTOP PROTEIN FLATTOP cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000014704.3|UniProtKB=G3RFH6 G3RFH6 ACTL8 PTHR11937:SF208 ACTIN ACTIN-LIKE PROTEIN 8 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807 GORGO|Ensembl=ENSGGOG00000006109.4|UniProtKB=G3QTG4 G3QTG4 ATP10B PTHR24092:SF79 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VB molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;intramembrane lipid carrier activity#GO:0140303 cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000005644.3|UniProtKB=G3QS98 G3QS98 CCP110 PTHR13594:SF1 CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;cell projection organization#GO:0030030;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000024859.2|UniProtKB=G3RLW0 G3RLW0 SRSF3 PTHR23147:SF121 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 3 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000013240.3|UniProtKB=G3RBQ0 G3RBQ0 NDUFAF3 PTHR21192:SF2 NUCLEAR PROTEIN E3-3 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3 mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007381.3|UniProtKB=G3QWR0 G3QWR0 DUS2 PTHR45936:SF1 TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000005264.3|UniProtKB=A0A2I2Y8X3 A0A2I2Y8X3 PTHR15415:SF7 MITOFILIN MICOS COMPLEX SUBUNIT MIC60 GORGO|Ensembl=ENSGGOG00000000958.3|UniProtKB=G3QF79 G3QF79 MTRR PTHR19384:SF84 NITRIC OXIDE SYNTHASE-RELATED METHIONINE SYNTHASE REDUCTASE anion binding#GO:0043168;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;catalytic activity#GO:0003824;carbohydrate derivative binding#GO:0097367;oxidoreductase activity, acting on metal ions#GO:0016722;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005018.3|UniProtKB=G3QQP5 G3QQP5 MTMR1 PTHR10807:SF40 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3-PHOSPHATE PHOSPHATASE MTMR1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000012963.3|UniProtKB=G3RB08 G3RB08 TPH2 PTHR11473:SF16 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 serotonin biosynthetic process#GO:0042427;biosynthetic process#GO:0009058;phenol-containing compound biosynthetic process#GO:0046189;phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;serotonin metabolic process#GO:0042428;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 GORGO|Ensembl=ENSGGOG00000005790.3|UniProtKB=G3QSN7 G3QSN7 PIK3R4 PTHR17583:SF0 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;establishment of protein localization#GO:0045184;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;macroautophagy#GO:0016236;metabolic process#GO:0008152;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;intracellular protein transport#GO:0006886;transport#GO:0006810;pexophagy#GO:0000425;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to vacuole#GO:0072666;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;protein targeting#GO:0006605;late endosome to vacuole transport#GO:0045324;protein localization to vacuole#GO:0072665;localization#GO:0051179;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031 extrinsic component of membrane#GO:0019898;transferase complex#GO:1990234;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex, class III#GO:0035032;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;organelle membrane contact site#GO:0044232;vesicle#GO:0031982 protein-binding activity modulator#PC00095;kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000028318.2|UniProtKB=G3S6D3 G3S6D3 TICAM2 PTHR47230:SF2 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;toll-like receptor signaling pathway#GO:0002224;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;positive regulation of type I interferon production#GO:0032481;positive regulation of signal transduction#GO:0009967;innate immune response-activating signaling pathway#GO:0002758;pattern recognition receptor signaling pathway#GO:0002221;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;activation of innate immune response#GO:0002218 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TRIF#P01344 GORGO|Ensembl=ENSGGOG00000015394.3|UniProtKB=G3RHA3 G3RHA3 SLC30A4 PTHR11562:SF27 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A4-RELATED transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 response to chemical#GO:0042221;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810;response to metal ion#GO:0010038;response to stimulus#GO:0050896;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000005384.3|UniProtKB=G3QRM3 G3QRM3 ABLIM3 PTHR24213:SF0 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 3 binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;actin filament bundle#GO:0032432;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000041345.1|UniProtKB=A0A2I2ZEL1 A0A2I2ZEL1 ATG12 PTHR13385:SF5 AUTOPHAGY PROTEIN 12 UBIQUITIN-LIKE PROTEIN ATG12 aminoacyltransferase activity#GO:0016755;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;carbohydrate catabolic process#GO:0016052;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;piecemeal microautophagy of the nucleus#GO:0034727;carbohydrate metabolic process#GO:0005975;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977 autophagosome#GO:0005776;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000042067.1|UniProtKB=A0A2I2Z3V4 A0A2I2Z3V4 PTHR15606:SF7 DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 8 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000043844.1|UniProtKB=A0A2I2ZUI9 A0A2I2ZUI9 NRIP1 PTHR15088:SF0 NUCLEAR FACTOR RIP140 NUCLEAR RECEPTOR-INTERACTING PROTEIN 1 transcription corepressor activity#GO:0003714;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;nuclear estrogen receptor binding#GO:0030331;transcription coactivator activity#GO:0003713;binding#GO:0005488;transcription regulator activity#GO:0140110;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;response to estradiol#GO:0032355;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;rhythmic process#GO:0048511;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000022931.2|UniProtKB=G3RV74 G3RV74 LOC109028938 PTHR26453:SF682 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G8 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011760.3|UniProtKB=G3R7W9 G3R7W9 ZSCAN10 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015836.3|UniProtKB=G3S4X6 G3S4X6 AFAP1 PTHR14338:SF8 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 actin cytoskeleton#GO:0015629;cytosol#GO:0005829;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;actin filament#GO:0005884;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000016060.3|UniProtKB=A0A2I2Z063 A0A2I2Z063 SERINC5 PTHR10383:SF16 SERINE INCORPORATOR SERINE INCORPORATOR 5 cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000005786.3|UniProtKB=A0A2I2Z4U2 A0A2I2Z4U2 TTC39B PTHR31859:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39B biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;lipid homeostasis#GO:0055088;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cholesterol homeostasis#GO:0042632;chemical homeostasis#GO:0048878;negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216 GORGO|Ensembl=ENSGGOG00000043853.1|UniProtKB=A0A2I2YIM0 A0A2I2YIM0 ISX PTHR24329:SF362 HOMEOBOX PROTEIN ARISTALESS INTESTINE-SPECIFIC HOMEOBOX double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000014791.3|UniProtKB=G3SCU2 G3SCU2 TRIM6 PTHR24103:SF647 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM34 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;immune system process#GO:0002376;biological regulation#GO:0065007;response to other organism#GO:0051707;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000003241.3|UniProtKB=G3SHH0 G3SHH0 RPL37 PTHR10768:SF22 60S RIBOSOMAL PROTEIN L37 LARGE RIBOSOMAL SUBUNIT PROTEIN EL37 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009686.3|UniProtKB=G3R2K9 G3R2K9 PPIL4 PTHR45843:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000023835.2|UniProtKB=G3S864 G3S864 PTHR22749:SF14 RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE RIBOFLAVIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;flavin-containing compound metabolic process#GO:0042726;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 Flavin biosynthesis#P02741>FAD synthetase#P02936;Flavin biosynthesis#P02741>Riboflavin kinase#P02934 GORGO|Ensembl=ENSGGOG00000017106.3|UniProtKB=A0A2I2Y3M2 A0A2I2Y3M2 ZNF518A PTHR24403:SF81 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 518A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000014641.3|UniProtKB=G3RFB7 G3RFB7 PTHR28584:SF3 FAMILY WITH SEQUENCE SIMILARITY 228 MEMBER A PROTEIN FAM228B GORGO|Ensembl=ENSGGOG00000015627.3|UniProtKB=G3RHW8 G3RHW8 KCTD13 PTHR11145:SF18 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER BTB_POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 1 negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of Rho protein signal transduction#GO:0035023;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006832.3|UniProtKB=G3QVD4 G3QVD4 POLN PTHR10133:SF65 DNA POLYMERASE I DNA POLYMERASE NU transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA-directed DNA polymerase activity#GO:0003887 double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238 DNA-directed DNA polymerase#PC00018 GORGO|Ensembl=ENSGGOG00000014975.3|UniProtKB=A0A2I2YL20 A0A2I2YL20 WASHC3 PTHR13015:SF2 PROTEIN AD-016-RELATED WASH COMPLEX SUBUNIT 3 transport#GO:0006810;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;exocytosis#GO:0006887;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;secretion by cell#GO:0032940;supramolecular fiber organization#GO:0097435;secretion#GO:0046903;localization#GO:0051179;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;export from cell#GO:0140352;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000012345.3|UniProtKB=G3R9H2 G3R9H2 TNKS1BP1 PTHR22042:SF2 TANKYRASE 1 BINDING PROTEIN 182 KDA TANKYRASE-1-BINDING PROTEIN DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular response to abiotic stimulus#GO:0071214;double-strand break repair#GO:0006302;response to stress#GO:0006950;response to radiation#GO:0009314;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;nucleic acid metabolic process#GO:0090304;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;response to ionizing radiation#GO:0010212;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;cellular response to radiation#GO:0071478 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;CCR4-NOT complex#GO:0030014;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000011260.3|UniProtKB=G3R6L6 G3R6L6 PTHR11987:SF48 ALPHA-2,8-SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-POLY-ALPHA-2,8-SIALYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;oligosaccharide metabolic process#GO:0009311 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003354.3|UniProtKB=G3QLE7 G3QLE7 TXLNB PTHR16127:SF10 TAXILIN BETA-TAXILIN membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000036937.1|UniProtKB=A0A2I2ZTS2 A0A2I2ZTS2 PTHR21859:SF50 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31D3-RELATED GORGO|Gene=VN1R1|UniProtKB=Q8WN92 Q8WN92 VN1R1 PTHR24062:SF199 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 1 binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008148.3|UniProtKB=G3QYM5 G3QYM5 ANXA13 PTHR10502:SF175 ANNEXIN ANNEXIN A13 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;anion binding#GO:0043168;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calcium-binding protein#PC00060 GORGO|Gene=HBA3_GORGO|UniProtKB=P01934 P01934 PTHR11442:SF79 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ALPHA-3 tetrapyrrole binding#GO:0046906;molecular carrier activity#GO:0140104;binding#GO:0005488;heme binding#GO:0020037 establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;developmental process#GO:0032502;transport#GO:0006810;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;cellular process#GO:0009987;localization#GO:0051179;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;cell development#GO:0048468 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 globin#PC00107;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000001174.3|UniProtKB=A0A2I2YYU4 A0A2I2YYU4 ZNF302 PTHR23226:SF128 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 30 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007686.3|UniProtKB=G3QXH5 G3QXH5 PTHR22811:SF3 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 11 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000038688.1|UniProtKB=G3S8R8 G3S8R8 PTHR24006:SF665 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000016401.3|UniProtKB=G3RJU7 G3RJU7 ZBTB4 PTHR24388:SF58 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004632.3|UniProtKB=G3QPN8 G3QPN8 LINS1 PTHR16057:SF1 WINS1, 2 PROTEIN PROTEIN LINES HOMOLOG 1 GORGO|Ensembl=ENSGGOG00000016568.3|UniProtKB=G3QWJ3 G3QWJ3 PTHR24377:SF765 IP01015P-RELATED ZINC FINGER PROTEIN 765 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014064.3|UniProtKB=A0A2I2ZDI3 A0A2I2ZDI3 BAIAP2 PTHR14206:SF3 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BAR_IMD DOMAIN-CONTAINING ADAPTER PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;actin filament bundle organization#GO:0061572;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006599.3|UniProtKB=G3QUQ0 G3QUQ0 KRT7 PTHR45616:SF21 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 7 structural molecule activity#GO:0005198 intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;developmental process#GO:0032502;epidermis development#GO:0008544 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000001047.3|UniProtKB=G3QFG1 G3QFG1 SLC14A2 PTHR10464:SF6 UREA TRANSPORTER UREA TRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 nitrogen compound transport#GO:0071705;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004002.3|UniProtKB=G3RT08 G3RT08 PABPC4 PTHR24012:SF365 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 4 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;single-stranded RNA binding#GO:0003727;mRNA binding#GO:0003729;binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003935.3|UniProtKB=G3QMW3 G3QMW3 USF1 PTHR46117:SF1 FI24210P1 UPSTREAM STIMULATORY FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000008567.3|UniProtKB=G3QZQ7 G3QZQ7 LOC101143505 PTHR23428:SF392 HISTONE H2B HISTONE H2B TYPE W-T response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000023696.2|UniProtKB=G3S6G3 G3S6G3 PTPRK PTHR19134:SF209 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE KAPPA protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;neuron differentiation#GO:0030182;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000011004.3|UniProtKB=G3RKZ5 G3RKZ5 LOC101135404 PTHR23262:SF71 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-5 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000005161.3|UniProtKB=G3SDY8 G3SDY8 SGPP1 PTHR14969:SF45 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 dephosphorylation#GO:0016311;lipid modification#GO:0030258;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000015663.3|UniProtKB=G3RHZ9 G3RHZ9 SLC52A1 PTHR12929:SF20 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;vitamin transport#GO:0051180;transport#GO:0006810;nitrogen compound transport#GO:0071705 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000008111.3|UniProtKB=A0A2I2YEN2 A0A2I2YEN2 PTHR24253:SF162 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 48 catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008741.3|UniProtKB=G3R067 G3R067 ITPA PTHR11067:SF9 INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN INOSINE TRIPHOSPHATE PYROPHOSPHATASE hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429 nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 nucleotide phosphatase#PC00173 GORGO|Ensembl=ENSGGOG00000013727.3|UniProtKB=G3RD11 G3RD11 A2M PTHR11412:SF165 MACROGLOBULIN / COMPLEMENT ALPHA-2-MACROGLOBULIN endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 defense response#GO:0006952;response to stimulus#GO:0050896;inflammatory response#GO:0006954;response to stress#GO:0006950 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>alpha2-macroglobulin#P00427 GORGO|Ensembl=ENSGGOG00000001194.3|UniProtKB=G3QFU7 G3QFU7 C2CD4C PTHR46291:SF5 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4C GORGO|Ensembl=ENSGGOG00000008019.3|UniProtKB=G3QYB0 G3QYB0 TNFRSF10D PTHR46330:SF10 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10D cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;apoptotic signaling pathway#GO:0097190;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;biological regulation#GO:0065007;cell communication#GO:0007154;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;signaling#GO:0023052 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 p53 pathway#P00059>KILLER/DR5#G01568;Apoptosis signaling pathway#P00006>TRAIL-R#P00276 GORGO|Ensembl=ENSGGOG00000015675.3|UniProtKB=G3RI11 G3RI11 FAM83D PTHR16181:SF30 PROTEIN FAM83A-RELATED PROTEIN FAM83D protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;localization#GO:0051179;cell communication#GO:0007154;protein localization to microtubule cytoskeleton#GO:0072698;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;macromolecule localization#GO:0033036;positive regulation of cellular process#GO:0048522;intracellular protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;protein localization to cytoskeleton#GO:0044380;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of MAPK cascade#GO:0043408 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitotic spindle pole#GO:0097431;cytosol#GO:0005829;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000004768.3|UniProtKB=G3QQ13 G3QQ13 LOC101139203 PTHR11387:SF16 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B1 respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;transporter complex#GO:1990351;organelle membrane#GO:0031090;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010586.3|UniProtKB=G3RSE2 G3RSE2 ABL1 PTHR24418:SF438 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 positive regulation of cell motility#GO:2000147;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of cell migration#GO:0030335;ERBB signaling pathway#GO:0038127;epidermal growth factor receptor signaling pathway#GO:0007173;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell migration#GO:0030334;cell surface receptor signaling pathway#GO:0007166;positive regulation of locomotion#GO:0040017 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 Axon guidance mediated by Slit/Robo#P00008>Abl#P00347;Integrin signalling pathway#P00034>Abl#P00946 GORGO|Ensembl=ENSGGOG00000042296.1|UniProtKB=A0A2I2ZVY9 A0A2I2ZVY9 LOC109026149 PTHR31699:SF7 NUDIX T16 FAMILY MEMBER U8 SNORNA-DECAPPING ENZYME RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;snoRNA binding#GO:0030515;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000014874.3|UniProtKB=G3RWY3 G3RWY3 SPRYD3 PTHR12864:SF89 RAN BINDING PROTEIN 9-RELATED SPRY DOMAIN-CONTAINING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 GORGO|Gene=APOBEC3G|UniProtKB=Q694C1 Q694C1 APOBEC3G PTHR13857:SF20 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3G binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 response to virus#GO:0009615;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cytidine to uridine editing#GO:0016554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;response to other organism#GO:0051707;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;base conversion or substitution editing#GO:0016553;RNA modification#GO:0009451;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular process#GO:0009987 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000002573.3|UniProtKB=G3QJE4 G3QJE4 RACGAP1 PTHR46199:SF3 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 organelle assembly#GO:0070925;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cellular response to stimulus#GO:0051716;cell division#GO:0051301;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;nuclear division#GO:0000280;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;Rho protein signal transduction#GO:0007266;regulation of biological process#GO:0050789;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;signaling#GO:0023052;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;intracellular signaling cassette#GO:0141124;cellular component assembly#GO:0022607 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular protein-containing complex#GO:0140535;cleavage furrow#GO:0032154;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;midbody#GO:0030496;membrane-bounded organelle#GO:0043227;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000013091.4|UniProtKB=G3RBF4 G3RBF4 HYDIN PTHR23053:SF0 DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 1 AXONEMAL CENTRAL PAIR APPARATUS PROTEIN HYDIN microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium movement#GO:0003341;microtubule bundle formation#GO:0001578;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000010454.3|UniProtKB=G3R4J5 G3R4J5 COG2 PTHR12961:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2 endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;Golgi organization#GO:0007030;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193 organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;COG complex#GO:0017119;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000005065.3|UniProtKB=G3QQU4 G3QQU4 DDX21 PTHR47958:SF109 ATP-DEPENDENT RNA HELICASE DBP3 NUCLEOLAR RNA HELICASE 2 isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000006605.3|UniProtKB=G3QUQ7 G3QUQ7 LOC101136849 PTHR22902:SF9 SESQUIPEDALIAN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY J MEMBER 1 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000002567.3|UniProtKB=A0A2I2ZB11 A0A2I2ZB11 DLD PTHR22912:SF151 DISULFIDE OXIDOREDUCTASE DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281 oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000027511.2|UniProtKB=G3S1U2 G3S1U2 SHLD1 PTHR36863:SF1 SHIELDIN COMPLEX SUBUNIT 1 SHIELDIN COMPLEX SUBUNIT 1 biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of immune effector process#GO:0002699;negative regulation of DNA metabolic process#GO:0051053;positive regulation of DNA repair#GO:0045739;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;positive regulation of developmental process#GO:0051094;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;positive regulation of double-strand break repair#GO:2000781;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte mediated immunity#GO:0002703;negative regulation of DNA recombination#GO:0045910;positive regulation of DNA metabolic process#GO:0051054;regulation of double-strand break repair#GO:2000779;positive regulation of lymphocyte activation#GO:0051251;positive regulation of biosynthetic process#GO:0009891;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;regulation of immune response#GO:0050776;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of B cell activation#GO:0050864;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of leukocyte activation#GO:0002696;negative regulation of metabolic process#GO:0009892;regulation of lymphocyte activation#GO:0051249;positive regulation of adaptive immune response#GO:0002821;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of DNA metabolic process#GO:0051052;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of cellular response to stress#GO:0080135;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of lymphocyte mediated immunity#GO:0002706;regulation of DNA recombination#GO:0000018 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;site of double-strand break#GO:0035861;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008037.3|UniProtKB=G3QYD0 G3QYD0 SDR9C7 PTHR43313:SF5 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY 9C MEMBER 7 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745 primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;cellular process#GO:0009987;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000025346.2|UniProtKB=G3S354 G3S354 SELENOF PTHR13077:SF6 SELENOPROTEIN F SELENOPROTEIN F catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000043991.1|UniProtKB=A0A2I2YY30 A0A2I2YY30 MALL PTHR22776:SF24 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MAL-LIKE PROTEIN signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789 vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane raft#GO:0045121;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane microdomain#GO:0098857;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008855.3|UniProtKB=G3S5H2 G3S5H2 DSG2 PTHR24025:SF1 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-2 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000042152.1|UniProtKB=A0A2I2YLM0 A0A2I2YLM0 SFTPC PTHR10800:SF7 PULMONARY SURFACTANT-ASSOCIATED PROTEIN C SURFACTANT PROTEIN C cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982 structural protein#PC00211;surfactant#PC00212 GORGO|Ensembl=ENSGGOG00000037227.1|UniProtKB=G3RXQ0 G3RXQ0 PTHR15438:SF5 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX INTERACTING PROTEIN FAMILY MEMBER B3-RELATED GORGO|Ensembl=ENSGGOG00000014957.3|UniProtKB=G3RG56 G3RG56 PTHR13191:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012425.3|UniProtKB=A0A2I2YB74 A0A2I2YB74 PTHR24100:SF159 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000006589.3|UniProtKB=A0A2I2YWJ8 A0A2I2YWJ8 NAA50 PTHR42919:SF41 N-ALPHA-ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 50 protein N-acyltransferase activity#GO:0140186;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740 sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic sister chromatid cohesion#GO:0007064;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 transferase#PC00220;acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000000196.3|UniProtKB=G3QD83 G3QD83 MIIP PTHR34831:SF1 MIGRATION AND INVASION-INHIBITORY PROTEIN MIGRATION AND INVASION-INHIBITORY PROTEIN GORGO|Ensembl=ENSGGOG00000026074.2|UniProtKB=G3S4P0 G3S4P0 PTHR23267:SF464 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 7-46 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000001065.3|UniProtKB=G3QFH8 G3QFH8 USP16 PTHR21646:SF12 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of protein stability#GO:0031647;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000037017.1|UniProtKB=A0A2I2YXT4 A0A2I2YXT4 FAM237A PTHR36690:SF2 PROTEIN FAM237A PROTEIN FAM237A GORGO|Ensembl=ENSGGOG00000010844.3|UniProtKB=G3R5J1 G3R5J1 VWC2 PTHR46252:SF4 BRORIN FAMILY MEMBER BRORIN regulation of BMP signaling pathway#GO:0030510;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 signaling receptor complex#GO:0043235;extracellular region#GO:0005576;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000007982.3|UniProtKB=G3SHE7 G3SHE7 PTHR14107:SF15 WD REPEAT PROTEIN DYSTROPHIA MYOTONICA WD REPEAT-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047 negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;biological regulation#GO:0065007;negative regulation of protein catabolic process#GO:0042177;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000036267.1|UniProtKB=A0A2I2Y523 A0A2I2Y523 TMEM200B PTHR31815:SF3 AGAP005329-PA TRANSMEMBRANE PROTEIN 200B GORGO|Ensembl=ENSGGOG00000011479.3|UniProtKB=G3R766 G3R766 UPK1B PTHR47110:SF2 TESTIS-SPECIFIC EXPRESSED PROTEIN 55 UROPLAKIN-1B apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011589.3|UniProtKB=A0A2I2YN63 A0A2I2YN63 PTHR28680:SF2 CENTROMERE PROTEIN X CENTROMERE PROTEIN X cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;resolution of meiotic recombination intermediates#GO:0000712;cellular process#GO:0009987;organelle organization#GO:0006996;DNA-templated DNA replication#GO:0006261;organelle fission#GO:0048285;sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;reproductive process#GO:0022414;homologous recombination#GO:0035825;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;DNA replication#GO:0006260;cell cycle#GO:0007049;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;meiosis I#GO:0007127 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000026875.2|UniProtKB=G3S5S1 G3S5S1 KATNAL1 PTHR23074:SF65 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 1 hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000015835.3|UniProtKB=G3RIE4 G3RIE4 GNPDA2 PTHR11280:SF9 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE DEAMINASE 2 catalytic activity#GO:0003824;binding#GO:0005488;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;protein binding#GO:0005515;deaminase activity#GO:0019239;identical protein binding#GO:0042802 amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carboxylic acid catabolic process#GO:0046395;amino sugar catabolic process#GO:0046348;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 isomerase#PC00135 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 GORGO|Ensembl=ENSGGOG00000022506.2|UniProtKB=A0A2I2Z4Q0 A0A2I2Z4Q0 CCDC198 PTHR16065:SF2 COILED-COIL DOMAIN CONTAINING 198 FACTOR ASSOCIATED WITH METABOLISM AND ENERGY GORGO|Ensembl=ENSGGOG00000040955.1|UniProtKB=A0A2I2YJA8 A0A2I2YJA8 PTHR13422:SF18 SIN3-HDAC COMPLEX-ASSOCIATED FACTOR SIN3-HDAC COMPLEX-ASSOCIATED FACTOR regulation of cell migration#GO:0030334;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell motility#GO:2000145;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Sin3-type complex#GO:0070822 GORGO|Ensembl=ENSGGOG00000038654.1|UniProtKB=A0A2I2ZEZ2 A0A2I2ZEZ2 GREM2 PTHR15283:SF2 GREMLIN 1 GREMLIN-2 binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine binding#GO:0019955 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000041735.1|UniProtKB=A0A2I2Y8P2 A0A2I2Y8P2 CD28 PTHR11494:SF7 CYTOTOXIC T-LYMPHOCYTE PROTEIN T-CELL-SPECIFIC SURFACE GLYCOPROTEIN CD28 regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of T cell proliferation#GO:0042129;immune response-activating cell surface receptor signaling pathway#GO:0002429;leukocyte activation#GO:0045321;positive regulation of cell adhesion#GO:0045785;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;cell communication#GO:0007154;cell activation#GO:0001775;regulation of immune response#GO:0050776;positive regulation of lymphocyte proliferation#GO:0050671;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of cellular process#GO:0048522;positive regulation of leukocyte proliferation#GO:0070665;regulation of leukocyte cell-cell adhesion#GO:1903037;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;response to stimulus#GO:0050896;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;positive regulation of T cell proliferation#GO:0042102;T cell activation#GO:0042110;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of T cell activation#GO:0050863;antigen receptor-mediated signaling pathway#GO:0050851;lymphocyte activation#GO:0046649;positive regulation of T cell activation#GO:0050870;regulation of multicellular organismal process#GO:0051239;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of mononuclear cell proliferation#GO:0032946;immune response-activating signaling pathway#GO:0002757;regulation of leukocyte proliferation#GO:0070663;cell surface receptor signaling pathway#GO:0007166;positive regulation of leukocyte activation#GO:0002696 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD28#P01313 GORGO|Ensembl=ENSGGOG00000038098.1|UniProtKB=A0A2I2YAN2 A0A2I2YAN2 ZNF22 PTHR16515:SF71 PR DOMAIN ZINC FINGER PROTEIN ZINC FINGER PROTEIN 22 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000004512.3|UniProtKB=G3QPD1 G3QPD1 NME4 PTHR11349:SF49 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE D, MITOCHONDRIAL phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;nucleoside triphosphate metabolic process#GO:0009141;cellular process#GO:0009987;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;nucleoside triphosphate biosynthetic process#GO:0009142 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transferase#PC00220;kinase#PC00137 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912;De novo purine biosynthesis#P02738>GDP kinase#P02891;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 GORGO|Ensembl=ENSGGOG00000005948.3|UniProtKB=G3QT14 G3QT14 TMEM68 PTHR22753:SF14 TRANSMEMBRANE PROTEIN 68 DGAT1_2-INDEPENDENT ENZYME SYNTHESIZING STORAGE LIPIDS cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000003129.3|UniProtKB=G3QKU0 G3QKU0 RNF141 PTHR12109:SF3 RING FINGER PROTEIN 141-RELATED RING FINGER PROTEIN 141 catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 GORGO|Ensembl=ENSGGOG00000005876.3|UniProtKB=G3QSV5 G3QSV5 POR PTHR19384:SF17 NITRIC OXIDE SYNTHASE-RELATED NADPH--CYTOCHROME P450 REDUCTASE oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;oxidoreductase activity, acting on NAD(P)H#GO:0016651;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Vitamin D metabolism and pathway#P04396>P450 reductase#P04605 GORGO|Ensembl=ENSGGOG00000001580.3|UniProtKB=A0A2I2YZK9 A0A2I2YZK9 OGFOD3 PTHR14650:SF1 PROLYL HYDROXYLASE-RELATED 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 3 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012203.3|UniProtKB=G3R941 G3R941 ERAP2 PTHR11533:SF239 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2 exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235 peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;catabolic process#GO:0009056;cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000026245.2|UniProtKB=G3RY91 G3RY91 BCL2L1 PTHR11256:SF12 BCL-2 RELATED BCL-2-LIKE PROTEIN 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;signaling#GO:0023052;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 CCKR signaling map#P06959>BCL2L1#P07117;Apoptosis signaling pathway#P00006>Bcl-xL#P00257;Apoptosis signaling pathway#P00006>Bcl-xS#P00323 GORGO|Ensembl=ENSGGOG00000016443.3|UniProtKB=G3RJY8 G3RJY8 NLRP11 PTHR45690:SF5 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 11 regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010268.4|UniProtKB=G3R436 G3R436 PRMT8 PTHR11006:SF47 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 8 protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone modifying activity#GO:0140993 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007141.3|UniProtKB=G3SJD0 G3SJD0 HPCAL1 PTHR23055:SF79 CALCIUM BINDING PROTEINS HIPPOCALCIN-LIKE PROTEIN 1 calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000006784.4|UniProtKB=G3QV80 G3QV80 CDC5L PTHR45885:SF6 CELL DIVISION CYCLE 5-LIKE PROTEIN CELL DIVISION CYCLE 5-LIKE PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;regulation of transcription by RNA polymerase II#GO:0006357;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 GORGO|Ensembl=ENSGGOG00000005054.3|UniProtKB=A0A2I2YV11 A0A2I2YV11 MED24 PTHR12898:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014729.3|UniProtKB=G3RFL0 G3RFL0 CDC27 PTHR12558:SF13 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 27 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;metaphase/anaphase transition of cell cycle#GO:0044784;regulation of chromosome segregation#GO:0051983;proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;mitotic cell cycle phase transition#GO:0044772;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cell division#GO:0051301;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;post-translational protein modification#GO:0043687;biological regulation#GO:0065007 organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007591.3|UniProtKB=A0A2I2Z512 A0A2I2Z512 IFNGR2 PTHR20859:SF46 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON GAMMA RECEPTOR 2 molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Interferon-gamma signaling pathway#P00035>IFNGR1#P00959;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866;Interferon-gamma signaling pathway#P00035>IFNGR2#P00957 GORGO|Ensembl=ENSGGOG00000008323.3|UniProtKB=G3QZ34 G3QZ34 PTHR24410:SF16 HL07962P-RELATED GALECTIN-3-BINDING PROTEIN defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010206.3|UniProtKB=G3RTG1 G3RTG1 PIK3R3 PTHR10155:SF2 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166 extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane protein complex#GO:0098796 kinase modulator#PC00140 Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168;Angiogenesis#P00005>PI3K#P00236;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;PI3 kinase pathway#P00048>p85#P01202;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363;T cell activation#P00053>PI3K#P01322;p53 pathway feedback loops 2#P04398>PI3K#P04661 GORGO|Ensembl=ENSGGOG00000024810.2|UniProtKB=G3S0D8 G3S0D8 RPS27 PTHR11594:SF1 40S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN ES27 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;nucleic acid biosynthetic process#GO:0141187;translation#GO:0006412;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000016295.3|UniProtKB=G3RJK5 G3RJK5 PM20D2 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;small molecule catabolic process#GO:0044282;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000001637.3|UniProtKB=G3QGZ6 G3QGZ6 ZNF385D PTHR23067:SF12 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385D intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003994.3|UniProtKB=G3QN15 G3QN15 BFSP2 PTHR23239:SF32 INTERMEDIATE FILAMENT PHAKININ intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104 organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000036641.1|UniProtKB=A0A2I2ZK90 A0A2I2ZK90 LOC134756385 PTHR10656:SF8 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;enzyme inhibitor activity#GO:0004857;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887 membrane#GO:0016020;cellular anatomical structure#GO:0110165 nucleotidyltransferase#PC00174;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000027707.2|UniProtKB=G3SHX8 G3SHX8 BTBD3 PTHR24410:SF27 HL07962P-RELATED BTB DOMAIN CONTAINING 3 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000004033.3|UniProtKB=G3QN51 G3QN51 CDA PTHR11644:SF2 CYTIDINE DEAMINASE CYTIDINE DEAMINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 nucleoside catabolic process#GO:0009164;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 deaminase#PC00088 Pyrimidine Metabolism#P02771>Cytidine Deaminase#P03130;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144 GORGO|Ensembl=ENSGGOG00000004184.3|UniProtKB=G3QNI8 G3QNI8 OPN1LW PTHR24240:SF17 OPSIN MEDIUM-WAVE-SENSITIVE OPSIN 1-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;detection of stimulus#GO:0051606;biological regulation#GO:0065007;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;cellular response to radiation#GO:0071478;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000012502.3|UniProtKB=G3R9W3 G3R9W3 PRRC2B PTHR14038:SF4 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2B RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000043612.1|UniProtKB=A0A2I2ZDT8 A0A2I2ZDT8 PTHR45883:SF5 HSC70-INTERACTING PROTEIN STI1 DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;heat shock protein binding#GO:0031072 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 GORGO|Ensembl=ENSGGOG00000015447.3|UniProtKB=A0A2I2YC51 A0A2I2YC51 PHLDB2 PTHR12156:SF21 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 2 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 basal part of cell#GO:0045178;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 EGF receptor signaling pathway#P00018>Gab#P00563 GORGO|Ensembl=ENSGGOG00000008672.3|UniProtKB=G3S641 G3S641 LSM11 PTHR21415:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 RNA binding#GO:0003723;snRNA binding#GO:0017069;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001668.3|UniProtKB=A0A2I2ZJA2 A0A2I2ZJA2 STX12 PTHR19957:SF88 SYNTAXIN SYNTAXIN-12 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;macroautophagy#GO:0016236;membrane organization#GO:0061024;organelle assembly#GO:0070925;vacuole organization#GO:0007033;localization#GO:0051179;vesicle fusion#GO:0006906;catabolic process#GO:0009056;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagosome organization#GO:1905037;establishment of protein localization#GO:0045184;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;cellular localization#GO:0051641;cellular component organization#GO:0016043 presynapse#GO:0098793;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;recycling endosome#GO:0055037;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 GORGO|Ensembl=ENSGGOG00000023704.2|UniProtKB=G3SGE8 G3SGE8 SLC35A5 PTHR10231:SF90 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-SUGAR TRANSPORTER PROTEIN SLC35A5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000000797.3|UniProtKB=G3QET5 G3QET5 DNAI2 PTHR12442:SF7 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 2 binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cilium movement#GO:0003341;organelle assembly#GO:0070925;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;outer dynein arm#GO:0036157;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;axonemal dynein complex#GO:0005858;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000028350.2|UniProtKB=G3S2W4 G3S2W4 PTHR16471:SF2 CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN-LIKE PROTEIN SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000011780.3|UniProtKB=G3SFE1 G3SFE1 PCNX3 PTHR12372:SF4 PECANEX PECANEX-LIKE PROTEIN 3 GORGO|Ensembl=ENSGGOG00000012925.3|UniProtKB=A0A2I2Y6Y9 A0A2I2Y6Y9 MTHFR PTHR45754:SF3 METHYLENETETRAHYDROFOLATE REDUCTASE METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH) catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168 biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule metabolic process#GO:0044281;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;carboxylic acid biosynthetic process#GO:0046394;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000000256.3|UniProtKB=G3QDD9 G3QDD9 PTHR18063:SF8 NF-E2 INDUCIBLE PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-2 deubiquitinase activity#GO:0101005;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 GORGO|Ensembl=ENSGGOG00000003592.3|UniProtKB=A0A2I2YDK6 A0A2I2YDK6 ATP2A2 PTHR42861:SF176 CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 2 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829 cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;homeostatic process#GO:0042592;regulation of heart contraction#GO:0008016;organelle assembly#GO:0070925;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;vacuole organization#GO:0007033;intracellular signal transduction#GO:0035556;biological regulation#GO:0065007;macroautophagy#GO:0016236;monoatomic ion transmembrane transport#GO:0034220;regulation of system process#GO:0044057;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium-mediated signaling#GO:0019722;intracellular monoatomic ion homeostasis#GO:0006873;regulation of muscle system process#GO:0090257;calcium ion transmembrane transport#GO:0070588;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of muscle contraction#GO:0006937;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;process utilizing autophagic mechanism#GO:0061919;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;monoatomic ion homeostasis#GO:0050801;signal transduction#GO:0007165;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component assembly#GO:0022607;monoatomic cation transmembrane transport#GO:0098655;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840;intracellular calcium ion homeostasis#GO:0006874;autophagosome assembly#GO:0000045;calcium ion transport#GO:0006816 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000022566.2|UniProtKB=A0A2I2YMN1 A0A2I2YMN1 PTHR45616:SF46 GATA-TYPE DOMAIN-CONTAINING PROTEIN IF ROD DOMAIN-CONTAINING PROTEIN anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000005423.3|UniProtKB=A0A2I2YCG2 A0A2I2YCG2 TEX35 PTHR36860:SF1 TESTIS-EXPRESSED PROTEIN 35 TESTIS-EXPRESSED PROTEIN 35 GORGO|Ensembl=ENSGGOG00000039421.1|UniProtKB=A0A2I2YQY9 A0A2I2YQY9 MRPL33 PTHR47037:SF1 39S RIBOSOMAL PROTEIN L33, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL33M mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001766.3|UniProtKB=A0A2I2Z6S9 A0A2I2Z6S9 ARID3B PTHR15348:SF3 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3B DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000009476.3|UniProtKB=G3R224 G3R224 ARHGAP6 PTHR12635:SF6 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE-ACTIVATING PROTEIN 6 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000042382.1|UniProtKB=A0A2I2Y5F5 A0A2I2Y5F5 SNX18 PTHR45827:SF4 SORTING NEXIN SORTING NEXIN-18 ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;plasma membrane organization#GO:0007009;cellular localization#GO:0051641;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;endocytosis#GO:0006897;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;endosomal transport#GO:0016197;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;membrane invagination#GO:0010324;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000038857.1|UniProtKB=A0A2I2YQQ2 A0A2I2YQQ2 CXCL11 PTHR12015:SF191 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 11 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000013680.3|UniProtKB=G3RCV8 G3RCV8 PTHR11461:SF125 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B12 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Gene=RING1|UniProtKB=A1YER5 A1YER5 RING1 PTHR46076:SF2 E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RING1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;chromatin binding#GO:0003682 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023098.3|UniProtKB=G3S625 G3S625 SRPK2 PTHR47634:SF6 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SRSF PROTEIN KINASE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;signal transduction#GO:0007165;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;response to stimulus#GO:0050896;mRNA metabolic process#GO:0016071;signaling#GO:0023052;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;cell communication#GO:0007154;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000024744.2|UniProtKB=G3S9I3 G3S9I3 DNAJC21 PTHR44029:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000028387.2|UniProtKB=G3RRC3 G3RRC3 CCL1 PTHR12015:SF5 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677 defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;taxis#GO:0042330;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stress#GO:0006950;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell migration#GO:0016477;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell motility#GO:2000145;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000043231.1|UniProtKB=A0A2I2ZJE7 A0A2I2ZJE7 PTHR23268:SF54 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 24-1 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000000128.3|UniProtKB=G3QD22 G3QD22 TRAM1L1 PTHR12371:SF9 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 1-LIKE 1 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000001142.3|UniProtKB=G3QFP8 G3QFP8 PTHR10122:SF20 CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle membrane#GO:0031090;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 oxidoreductase#PC00176;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000010167.3|UniProtKB=G3R3U8 G3R3U8 ATP2B2 PTHR24093:SF377 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 homeostatic process#GO:0042592;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074 postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;membrane-bounded organelle#GO:0043227;postsynaptic density membrane#GO:0098839;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000004541.3|UniProtKB=G3QPG1 G3QPG1 CDKAL1 PTHR11918:SF45 RADICAL SAM PROTEINS THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000014037.3|UniProtKB=G3RPF5 G3RPF5 FBXL18 PTHR16134:SF19 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 18 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000452.3|UniProtKB=A0A2I2ZEQ5 A0A2I2ZEQ5 FLI1 PTHR11849:SF161 ETS FRIEND LEUKEMIA INTEGRATION 1 TRANSCRIPTION FACTOR DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000009020.3|UniProtKB=G3R0Y9 G3R0Y9 NBEAL2 PTHR13743:SF111 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 2 developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;anatomical structure formation involved in morphogenesis#GO:0048646;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;myeloid cell differentiation#GO:0030099;hemopoiesis#GO:0030097;cell development#GO:0048468 cytosol#GO:0005829;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027731.2|UniProtKB=G3SC36 G3SC36 NBN PTHR12162:SF0 NIBRIN-RELATED NIBRIN DNA binding#GO:0003677;damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488 DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of cell cycle G2/M phase transition#GO:1902750;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;cellular response to stress#GO:0033554;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000005516.3|UniProtKB=G3QRZ4 G3QRZ4 PRPF8 PTHR11140:SF0 PRE-MRNA SPLICING FACTOR PRP8 PRE-MRNA-PROCESSING-SPLICING FACTOR 8 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000013626.3|UniProtKB=G3RCQ9 G3RCQ9 PRCC PTHR13621:SF2 PROLINE-RICH PROTEIN PRCC PROLINE-RICH PROTEIN PRCC intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002332.3|UniProtKB=G3QIT2 G3QIT2 NOTCH4 PTHR24033:SF234 EGF-LIKE DOMAIN-CONTAINING PROTEIN SUSHI, NIDOGEN AND EGF LIKE DOMAINS 1 cellular process#GO:0009987;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;circulatory system development#GO:0072359;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;vasculature development#GO:0001944;system development#GO:0048731 Angiogenesis#P00005>Notch#P00255;Notch signaling pathway#P00045>Notch#P01099;Notch signaling pathway#P00045>NIct#P01119;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Notch signaling pathway#P00045>Next#P01103;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179;Alzheimer disease-presenilin pathway#P00004>NICD#P00122;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171;Notch signaling pathway#P00045>NIcs#P01120;Notch signaling pathway#P00045>Ntm#P01114;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154 GORGO|Ensembl=ENSGGOG00000010541.3|UniProtKB=G3R4R8 G3R4R8 CTBP1 PTHR46029:SF2 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 1 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 GORGO|Ensembl=ENSGGOG00000040942.1|UniProtKB=G3QJ97 G3QJ97 LOC101151126 PTHR48018:SF100 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014663.3|UniProtKB=G3RFD8 G3RFD8 LOC101132703 PTHR45616:SF8 GATA-TYPE DOMAIN-CONTAINING PROTEIN IF ROD DOMAIN-CONTAINING PROTEIN striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;cell development#GO:0048468;actomyosin structure organization#GO:0031032;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000011708.3|UniProtKB=G3R7S3 G3R7S3 GPR153 PTHR16518:SF5 G-PROTEIN COUPLED RECEPTOR 153, 162 G PROTEIN-COUPLED RECEPTOR 153-RELATED G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005779.3|UniProtKB=G3QSM1 G3QSM1 KLHL7 PTHR24412:SF435 KELCH PROTEIN KELCH-LIKE PROTEIN 7 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010819.3|UniProtKB=G3R5I2 G3R5I2 ATP6V0A1 PTHR11629:SF68 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 1 proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;binding#GO:0005488;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801;organelle organization#GO:0006996;monoatomic cation transmembrane transport#GO:0098655;vesicle-mediated transport#GO:0016192;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle-mediated transport in synapse#GO:0099003;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;process utilizing autophagic mechanism#GO:0061919;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular localization#GO:0051641;cellular component disassembly#GO:0022411;transmembrane transport#GO:0055085;monoatomic ion transmembrane transport#GO:0034220;macroautophagy#GO:0016236;biological regulation#GO:0065007;developmental maturation#GO:0021700;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;developmental process#GO:0032502;autophagosome maturation#GO:0097352;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;proton transmembrane transport#GO:1902600;homeostatic process#GO:0042592;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;localization#GO:0051179;monoatomic cation transport#GO:0006812 vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000023305.2|UniProtKB=A0A2I2YYS9 A0A2I2YYS9 PTHR46109:SF4 PROTEIN LIN-28 LIN28A RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015285.3|UniProtKB=G3RH01 G3RH01 GPN1 PTHR21231:SF8 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 1 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208;protein-binding activity modulator#PC00095;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000036852.1|UniProtKB=A0A2I2ZSM5 A0A2I2ZSM5 PTHR46595:SF6 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000001684.3|UniProtKB=G3RPB3 G3RPB3 TPT1 PTHR11991:SF9 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TPT1-LIKE PROTEIN-RELATED ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of programmed cell death#GO:0043069;regulation of metabolic process#GO:0019222;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;negative regulation of catabolic process#GO:0009895;negative regulation of cell communication#GO:0010648;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of signaling#GO:0023057 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000010205.3|UniProtKB=G3S586 G3S586 AKT1S1 PTHR21844:SF2 AKT1 SUBSTRATE 1 PROTEIN PROLINE-RICH AKT1 SUBSTRATE 1 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of TOR signaling#GO:0032006;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262;regulation of TORC1 signaling#GO:1903432 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 CCKR signaling map#P06959>PRAS40#P07076 GORGO|Ensembl=ENSGGOG00000001453.3|UniProtKB=G3QGH7 G3QGH7 BUD23 PTHR12734:SF0 METHYLTRANSFERASE-RELATED 18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;rRNA methyltransferase activity#GO:0008649;rRNA (guanine) methyltransferase activity#GO:0016435;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 transport#GO:0006810;rRNA metabolic process#GO:0016072;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;organelle localization#GO:0051640;nuclear transport#GO:0051169;nuclear export#GO:0051168;rRNA processing#GO:0006364;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000025011.2|UniProtKB=G3SAV6 G3SAV6 PTHR45632:SF6 LD33804P KELCH-LIKE PROTEIN 14 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cell projection#GO:0042995;cullin-RING ubiquitin ligase complex#GO:0031461;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell body#GO:0044297;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;neuron projection#GO:0043005 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011185.3|UniProtKB=G3R6F5 G3R6F5 DRG1 PTHR43127:SF1 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 1 carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000028139.2|UniProtKB=G3RZG1 G3RZG1 FAM72A PTHR31841:SF1 PROTEIN FAM72A-RELATED PROTEIN FAM72A-RELATED cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015556.3|UniProtKB=G3RHR8 G3RHR8 SYCP1 PTHR46918:SF1 SYNAPTONEMAL COMPLEX PROTEIN 1 SYNAPTONEMAL COMPLEX PROTEIN 1 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;homologous chromosome pairing at meiosis#GO:0007129;synaptonemal complex assembly#GO:0007130;cellular component assembly#GO:0022607;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reproductive process#GO:0022414;homologous recombination#GO:0035825;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;central element#GO:0000801;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000004961.3|UniProtKB=G3QQJ6 G3QQJ6 SVOPL PTHR24064:SF457 SOLUTE CARRIER FAMILY 22 MEMBER TRANSPORTER SVOPL-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000039310.1|UniProtKB=A0A2I2ZH82 A0A2I2ZH82 PTHR21026:SF2 39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005964.3|UniProtKB=G3S0U2 G3S0U2 PTHR11955:SF144 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 5-LIKE PROTEIN 3-RELATED fatty acid binding#GO:0005504;lipid binding#GO:0008289;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;organic acid binding#GO:0043177 monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000024584.2|UniProtKB=G3S233 G3S233 PRDM9 PTHR16515:SF10 PR DOMAIN ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9 transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;histone H3K36 methyltransferase activity#GO:0046975;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;binding#GO:0005488;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;DNA binding#GO:0003677;histone H3 methyltransferase activity#GO:0140938;histone H3K4 methyltransferase activity#GO:0042800;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;nucleic acid binding#GO:0003676;N-methyltransferase activity#GO:0008170 regulation of reproductive process#GO:2000241;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of nuclear division#GO:0051783;positive regulation of cell cycle#GO:0045787;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;positive regulation of DNA metabolic process#GO:0051054;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;positive regulation of metabolic process#GO:0009893;positive regulation of organelle organization#GO:0010638;regulation of DNA recombination#GO:0000018;positive regulation of cellular component organization#GO:0051130 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000015416.3|UniProtKB=G3RHC1 G3RHC1 ASB2 PTHR24173:SF33 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 2 developmental process#GO:0032502;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;animal organ development#GO:0048513;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;heart development#GO:0007507;multicellular organismal process#GO:0032501;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;circulatory system development#GO:0072359;catabolic process#GO:0009056 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014773.3|UniProtKB=G3RFP3 G3RFP3 FRMD8 PTHR13283:SF10 KREV INTERACTION TRAPPED 1-RELATED FERM DOMAIN-CONTAINING PROTEIN 8 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014643.3|UniProtKB=G3RFD3 G3RFD3 SEC31B PTHR13923:SF22 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31B vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043 coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000028132.2|UniProtKB=G3S655 G3S655 UBQLNL PTHR10677:SF9 UBIQUILIN UBIQUILIN-LIKE PROTEIN polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030;protein binding#GO:0005515 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000043727.1|UniProtKB=G3QF62 G3QF62 PTHR45973:SF19 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN AXONEMAL ASSEMBLY FACTOR 1 protein-containing complex binding#GO:0044877;binding#GO:0005488 developmental process#GO:0032502;left/right pattern formation#GO:0060972;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;determination of bilateral symmetry#GO:0009855;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;regionalization#GO:0003002;multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;cilium organization#GO:0044782;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;determination of left/right symmetry#GO:0007368;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030 cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000014600.3|UniProtKB=G3RF80 G3RF80 RDH12 PTHR43157:SF32 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 12 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000040118.1|UniProtKB=A0A2I2YWI6 A0A2I2YWI6 GNG13 PTHR15936:SF2 GUANINE NUCLEOTIDE-BINDING PROTEIN G I /G S /G O GAMMA-13 SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-13 binding#GO:0005488;protein binding#GO:0005515 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;catalytic complex#GO:1902494 G-protein#PC00020;heterotrimeric G-protein#PC00117;protein-binding activity modulator#PC00095 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Wnt signaling pathway#P00057>Ggamma#P01465 GORGO|Ensembl=ENSGGOG00000017181.3|UniProtKB=G3RLV6 G3RLV6 PIP4P2 PTHR21014:SF5 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE TYPE 2 PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 4-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;dephosphorylation#GO:0016311;lipid modification#GO:0030258 late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;late endosome#GO:0005770;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000011502.3|UniProtKB=G3S4D1 G3S4D1 FER1L6 PTHR12546:SF37 FER-1-LIKE FER-1-LIKE PROTEIN 6 membrane organization#GO:0061024;endomembrane system organization#GO:0010256;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000000688.3|UniProtKB=A0A2I2Y5J7 A0A2I2Y5J7 ZSCAN9 PTHR23226:SF15 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011488.3|UniProtKB=G3R776 G3R776 IL1R2 PTHR11890:SF3 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR TYPE 2 transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009324.3|UniProtKB=G3S125 G3S125 COL12A1 PTHR24020:SF17 COLLAGEN ALPHA COLLAGEN ALPHA-1(XII) CHAIN gastrulation#GO:0007369;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;formation of primary germ layer#GO:0001704;anatomical structure development#GO:0048856;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;embryo development#GO:0009790;endoderm formation#GO:0001706;developmental process#GO:0032502;cellular developmental process#GO:0048869;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;endoderm development#GO:0007492;anatomical structure formation involved in morphogenesis#GO:0048646 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863 GORGO|Ensembl=ENSGGOG00000042201.1|UniProtKB=A0A2I2ZN30 A0A2I2ZN30 PTHR23428:SF357 HISTONE H2B HISTONE H2B TYPE 1-K defense response#GO:0006952;response to external stimulus#GO:0009605;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000024123.2|UniProtKB=A0A2I2YEG3 A0A2I2YEG3 PTHR11523:SF50 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;export from cell#GO:0140352;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;monoatomic cation transport#GO:0006812;potassium ion homeostasis#GO:0055075;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000042922.1|UniProtKB=A0A2I2Z3W5 A0A2I2Z3W5 PTHR11265:SF3 S-ADENOSYL-METHYLTRANSFERASE MRAW METTL15 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a rRNA#GO:0140102 rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;rRNA base methylation#GO:0070475;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000003552.3|UniProtKB=G3QLW7 G3QLW7 EDC3 PTHR13612:SF0 ENHANCER OF MRNA-DECAPPING PROTEIN 3 ENHANCER OF MRNA-DECAPPING PROTEIN 3 molecular condensate scaffold activity#GO:0140693;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;P-body assembly#GO:0033962;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;organelle assembly#GO:0070925;RNA decapping#GO:0110154;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;membraneless organelle assembly#GO:0140694;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;organelle organization#GO:0006996;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000009708.3|UniProtKB=G3R2M0 G3R2M0 ABHD17B PTHR12277:SF48 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17B hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;palmitoyl hydrolase activity#GO:0098599;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of synapse organization#GO:0050807;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;negative regulation of biological process#GO:0048519;regulation of postsynapse organization#GO:0099175;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007 plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000001659.3|UniProtKB=G3QH16 G3QH16 LOC115931864 PTHR38140:SF7 KERATIN-ASSOCIATED PROTEIN 19-3-RELATED KERATIN-ASSOCIATED PROTEIN 19-7 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000012898.3|UniProtKB=A0A2I2ZJ34 A0A2I2ZJ34 SYNCRIP PTHR21245:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Q mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010283.3|UniProtKB=A0A2I2YA53 A0A2I2YA53 IL22RA2 PTHR20859:SF51 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001837.3|UniProtKB=G3QHI2 G3QHI2 RPS20 PTHR11700:SF8 30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US10 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000022435.2|UniProtKB=G3SAR5 G3SAR5 ZMYM5 PTHR45736:SF7 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 5 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000006199.3|UniProtKB=G3QTP2 G3QTP2 POMT2 PTHR10050:SF46 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 2 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006507.3|UniProtKB=G3RW49 G3RW49 CCDC33 PTHR21623:SF2 SPERIOLIN-BINDING FACTOR COILED-COIL DOMAIN-CONTAINING PROTEIN 33 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000005257.3|UniProtKB=G3RUV4 G3RUV4 GOLIM4 PTHR22909:SF22 GOLGI INTEGRAL MEMBRANE PROTEIN 4 GOLGI INTEGRAL MEMBRANE PROTEIN 4 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000006508.3|UniProtKB=G3QUG3 G3QUG3 PTHR11105:SF0 CITRATE LYASE SUBUNIT BETA-RELATED CITRAMALYL-COA LYASE, MITOCHONDRIAL lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 lyase#PC00144 Pyruvate metabolism#P02772>Citrate Lyase#P03137 GORGO|Ensembl=ENSGGOG00000027193.2|UniProtKB=G3S6A4 G3S6A4 INPP4B PTHR12187:SF3 AGAP000124-PA INOSITOL POLYPHOSPHATE 4-PHOSPHATASE TYPE II phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000013401.3|UniProtKB=G3RC51 G3RC51 SLC39A2 PTHR11040:SF120 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP2 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000010955.3|UniProtKB=G3R5V0 G3R5V0 CLCN4 PTHR45711:SF2 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000001121.3|UniProtKB=G3QFM7 G3QFM7 PPIC PTHR11071:SF11 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000011736.3|UniProtKB=G3R7V0 G3R7V0 DECR2 PTHR43296:SF12 PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING] oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000017049.3|UniProtKB=G3RLI6 G3RLI6 NUDT7 PTHR12992:SF48 NUDIX HYDROLASE PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;sulfur compound catabolic process#GO:0044273;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;organophosphate catabolic process#GO:0046434 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000000655.3|UniProtKB=G3QEF3 G3QEF3 HEATR5A PTHR21663:SF1 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5A macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104 intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011476.3|UniProtKB=G3SJ42 G3SJ42 SPPL2C PTHR12174:SF38 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2C endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;cytoplasmic vesicle membrane#GO:0030659;vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;Golgi-associated vesicle membrane#GO:0030660;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;side of membrane#GO:0098552;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827 protein modifying enzyme#PC00260;aspartic protease#PC00053 GORGO|Ensembl=ENSGGOG00000014799.3|UniProtKB=G3S3H4 G3S3H4 JPH4 PTHR23085:SF14 GH28348P JUNCTOPHILIN-4 regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008 sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000042055.1|UniProtKB=G3S0C9 G3S0C9 LDLRAD1 PTHR22722:SF20 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000044039.1|UniProtKB=G3S893 G3S893 C21H20orf141 PTHR39222:SF1 MCG9903 RIKEN CDNA 1700020A23 GENE GORGO|Ensembl=ENSGGOG00000027351.2|UniProtKB=G3SAF3 G3SAF3 CLVS2 PTHR10174:SF73 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CLAVESIN-2 ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936 cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component organization#GO:0016043;organelle organization#GO:0006996;lysosome organization#GO:0007040;lytic vacuole organization#GO:0080171;cellular process#GO:0009987 Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000015722.3|UniProtKB=G3RI55 G3RI55 PIWIL1 PTHR22891:SF46 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;nuclease activity#GO:0004518 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;multicellular organismal reproductive process#GO:0048609;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;male gamete generation#GO:0048232;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 membrane-bounded organelle#GO:0043227;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000006929.3|UniProtKB=G3QVL0 G3QVL0 FRMPD1 PTHR46221:SF2 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 1 membrane#GO:0016020;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000012884.3|UniProtKB=A0A2I2ZHL3 A0A2I2ZHL3 NR2C1 PTHR24083:SF49 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 1 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000005167.3|UniProtKB=G3QR27 G3QR27 CRYAB PTHR45640:SF5 HEAT SHOCK PROTEIN HSP-12.2-RELATED ALPHA-CRYSTALLIN B CHAIN protein refolding#GO:0042026;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein folding#GO:0006457;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;negative regulation of programmed cell death#GO:0043069;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to heat#GO:0009408;response to stress#GO:0006950;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;negative regulation of apoptotic process#GO:0043066;gene expression#GO:0010467;protein maturation#GO:0051604 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 GORGO|Ensembl=ENSGGOG00000008790.3|UniProtKB=G3R0A9 G3R0A9 IPMK PTHR12400:SF80 INOSITOL POLYPHOSPHATE KINASE INOSITOL POLYPHOSPHATE MULTIKINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;organophosphate biosynthetic process#GO:0090407 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000037793.1|UniProtKB=G3R5R0 G3R5R0 PMF1 PTHR15459:SF5 POLYAMINE-MODULATED FACTOR 1 POLYAMINE MODULATED FACTOR 1 cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;chromosome segregation#GO:0007059 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775 GORGO|Ensembl=ENSGGOG00000026027.2|UniProtKB=A0A2I2YUQ5 A0A2I2YUQ5 PTHR16967:SF1 LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell population proliferation#GO:0008284;biological regulation#GO:0065007;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 GORGO|Ensembl=ENSGGOG00000016246.3|UniProtKB=G3RWB7 G3RWB7 PTHR42796:SF6 FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED FUMARYLACETOACETATE HYDROLASE DOMAIN CONTAINING 2B hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000001501.3|UniProtKB=A0A2I2ZDN4 A0A2I2ZDN4 GCK PTHR19443:SF3 HEXOKINASE HEXOKINASE-4 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleotide catabolic process#GO:0009166;intracellular chemical homeostasis#GO:0055082;energy derivation by oxidation of organic compounds#GO:0015980;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;regulation of establishment of protein localization#GO:0070201;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;regulation of secretion#GO:0051046;organophosphate catabolic process#GO:0046434;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;homeostatic process#GO:0042592;glucose 6-phosphate metabolic process#GO:0051156;catabolic process#GO:0009056;chemical homeostasis#GO:0048878;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;regulation of localization#GO:0032879;regulation of transport#GO:0051049;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;oxoacid metabolic process#GO:0043436;regulation of secretion by cell#GO:1903530;regulation of protein localization#GO:0032880;intracellular glucose homeostasis#GO:0001678;regulation of hormone levels#GO:0010817;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;pyridine nucleotide catabolic process#GO:0019364;regulation of protein transport#GO:0051223;small molecule metabolic process#GO:0044281;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;cellular homeostasis#GO:0019725;ADP metabolic process#GO:0046031;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;purine nucleoside triphosphate metabolic process#GO:0009144;regulation of protein secretion#GO:0050708;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;nucleoside triphosphate metabolic process#GO:0009141;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;regulation of cellular process#GO:0050794;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;glucose homeostasis#GO:0042593;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;regulation of insulin secretion#GO:0050796;regulation of signaling#GO:0023051;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;regulation of biological quality#GO:0065008;regulation of hormone secretion#GO:0046883;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;cytoplasmic side of membrane#GO:0098562;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000026987.2|UniProtKB=A0A2I2Y5W3 A0A2I2Y5W3 PTHR10836:SF89 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000023379.2|UniProtKB=G3SGT1 G3SGT1 TSPAN5 PTHR19282:SF63 TETRASPANIN TETRASPANIN-5 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012654.2|UniProtKB=G3RA80 G3RA80 WNT7A PTHR12027:SF78 WNT RELATED PROTEIN WNT-7A molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102 Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;system development#GO:0048731;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of JNK cascade#GO:0046328;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 GORGO|Ensembl=ENSGGOG00000024126.2|UniProtKB=G3RYT7 G3RYT7 MFSD1 PTHR23512:SF13 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 LYSOSOMAL DIPEPTIDE TRANSPORTER MFSD1 lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003203.3|UniProtKB=G3QL10 G3QL10 DMGDH PTHR13847:SF187 SARCOSINE DEHYDROGENASE-RELATED DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000037546.1|UniProtKB=A0A2I2Z7X5 A0A2I2Z7X5 IQCG PTHR14871:SF1 DYNEIN REGULATORY COMPLEX PROTEIN 9 DYNEIN REGULATORY COMPLEX PROTEIN 9 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;spermatogenesis#GO:0007283;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286 motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;9+2 motile cilium#GO:0097729;cilium#GO:0005929 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000015712.3|UniProtKB=G3RI39 G3RI39 IRX2 PTHR11211:SF15 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000012275.3|UniProtKB=G3R9A7 G3R9A7 CTSH PTHR12411:SF1044 CYSTEINE PROTEASE FAMILY C1-RELATED PRO-CATHEPSIN H molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;peptidase regulator activity#GO:0061134;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;peptidase activator activity#GO:0016504;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047 protein metabolic process#GO:0019538;proteolysis#GO:0006508;immune system process#GO:0002376;protein catabolic process#GO:0030163;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;zymogen activation#GO:0031638;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;adaptive immune response#GO:0002250;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;immune response#GO:0006955 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000003009.3|UniProtKB=G3QKI4 G3QKI4 CDH11 PTHR24027:SF85 CADHERIN-23 CADHERIN-11 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell adhesion#GO:0007155;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell junction organization#GO:0034330;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell migration#GO:0016477;cellular component assembly#GO:0022607 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;anchoring junction#GO:0070161;adherens junction#GO:0005912 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000010528.3|UniProtKB=G3R4Q9 G3R4Q9 AREG PTHR10740:SF12 TRANSFORMING GROWTH FACTOR ALPHA AMPHIREGULIN protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851 regulation of mitotic nuclear division#GO:0007088;cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of cell cycle#GO:0045787;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;epidermal growth factor receptor signaling pathway#GO:0007173;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 GORGO|Ensembl=ENSGGOG00000002542.3|UniProtKB=G3QJB4 G3QJB4 SWSAP1 PTHR28653:SF1 FAMILY NOT NAMED ATPASE SWSAP1 GORGO|Ensembl=ENSGGOG00000024381.2|UniProtKB=G3RWS7 G3RWS7 RPSA PTHR11489:SF20 40S RIBOSOMAL PROTEIN SA 40S RIBOSOMAL PROTEIN SA structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000023342.2|UniProtKB=A0A2I2ZV18 A0A2I2ZV18 PTHR24388:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 341 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007095.3|UniProtKB=A0A2I2YB63 A0A2I2YB63 BRD8 PTHR15398:SF4 BROMODOMAIN-CONTAINING PROTEIN 8 BROMODOMAIN-CONTAINING PROTEIN 8 GORGO|Ensembl=ENSGGOG00000001874.4|UniProtKB=G3QHL9 G3QHL9 SPECC1 PTHR23167:SF3 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED CYTOSPIN-B cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080 scaffold/adaptor protein#PC00226 GORGO|Gene=TBX6|UniProtKB=A1YF56 A1YF56 TBX6 PTHR11267:SF100 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 GORGO|Ensembl=ENSGGOG00000000458.3|UniProtKB=A0A2I2ZX41 A0A2I2ZX41 AP2A2 PTHR22780:SF30 ADAPTIN, ALPHA/GAMMA/EPSILON AP-2 COMPLEX SUBUNIT ALPHA-2 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;endocytic vesicle#GO:0030139;coated membrane#GO:0048475;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;clathrin vesicle coat#GO:0030125;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;plasma membrane#GO:0005886;endomembrane system#GO:0012505;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090 membrane traffic protein#PC00150 Huntington disease#P00029>alpha-Adaptin#P00782 GORGO|Ensembl=ENSGGOG00000025994.2|UniProtKB=G3RTW2 G3RTW2 ZFC3H1 PTHR21563:SF3 ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000008663.3|UniProtKB=A0A2I2YAD3 A0A2I2YAD3 MIER1 PTHR10865:SF24 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 1 enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein binding#GO:0005515;histone deacetylase binding#GO:0042826 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000022523.2|UniProtKB=G3RS72 G3RS72 BLTP3B PTHR22774:SF17 CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 3B lipid transfer activity#GO:0120013;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215 Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;lipid transport#GO:0006869;lipid localization#GO:0010876;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;cytosolic transport#GO:0016482 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 GORGO|Ensembl=ENSGGOG00000003296.3|UniProtKB=G3QL91 G3QL91 TESK2 PTHR46485:SF6 LIM DOMAIN KINASE 1 DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 2 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000012696.3|UniProtKB=G3RAC3 G3RAC3 TMTC3 PTHR44395:SF1 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC3 GORGO|Ensembl=ENSGGOG00000010865.4|UniProtKB=G3R5L9 G3R5L9 SPHKAP PTHR10226:SF7 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN SPHKAP protein kinase A binding#GO:0051018;binding#GO:0005488;protein binding#GO:0005515 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005761.3|UniProtKB=G3QSK2 G3QSK2 CTCFL PTHR24392:SF61 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR CTCF transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007160.3|UniProtKB=A0A2I2YGS7 A0A2I2YGS7 GUCY1B1 PTHR45655:SF2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1 phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829 response to abiotic stimulus#GO:0009628;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;response to oxygen levels#GO:0070482;nucleoside phosphate metabolic process#GO:0006753;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293 catalytic complex#GO:1902494;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 guanylate cyclase#PC00114;cyclase#PC00079 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581;Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726 GORGO|Ensembl=ENSGGOG00000003967.3|UniProtKB=G3QMZ6 G3QMZ6 PAQR5 PTHR20855:SF38 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR GAMMA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000024945.2|UniProtKB=G3S984 G3S984 PTHR21646:SF27 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 8 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;vesicle organization#GO:0016050;endosome organization#GO:0007032;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;intracellular signaling cassette#GO:0141124;positive regulation of Wnt signaling pathway#GO:0030177;signal transduction#GO:0007165;regulation of protein stability#GO:0031647;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of canonical Wnt signaling pathway#GO:0060828;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;midbody#GO:0030496;postsynapse#GO:0098794;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;postsynaptic density#GO:0014069 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000001029.3|UniProtKB=G3QFE3 G3QFE3 GABPB2 PTHR24193:SF86 ANKYRIN REPEAT PROTEIN GA-BINDING PROTEIN SUBUNIT BETA-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000022688.1|UniProtKB=G3S388 G3S388 ND5 PTHR42829:SF4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 monoatomic ion transport#GO:0006811;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002563.3|UniProtKB=G3QJD2 G3QJD2 PRSS42P PTHR24253:SF159 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 42 serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000015414.3|UniProtKB=A0A2I2YVC3 A0A2I2YVC3 NAPG PTHR13768:SF2 SOLUBLE NSF ATTACHMENT PROTEIN SNAP GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000025208.2|UniProtKB=G3S3H8 G3S3H8 PTHR31131:SF2 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 2 negative regulation of intracellular signal transduction#GO:1902532;response to nitrogen compound#GO:1901698;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;cellular response to amino acid stimulus#GO:0071230;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Gene=AGT|UniProtKB=Q9GLP6 Q9GLP6 AGT PTHR11461:SF13 SERINE PROTEASE INHIBITOR, SERPIN ANGIOTENSINOGEN serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to hormone#GO:0009725;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;regulation of apoptotic process#GO:0042981;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>AngII#P05935 GORGO|Ensembl=ENSGGOG00000008532.3|UniProtKB=G3RW96 G3RW96 TNFRSF18 PTHR47388:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 18 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 18 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell adhesion#GO:0045785;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003270.3|UniProtKB=G3QL69 G3QL69 LOC101149205 PTHR26453:SF570 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008980.3|UniProtKB=A0A2I2YDR9 A0A2I2YDR9 GYG1 PTHR11183:SF164 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;glucosyltransferase activity#GO:0046527 generation of precursor metabolites and energy#GO:0006091;glycogen biosynthetic process#GO:0005978;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112;glucan biosynthetic process#GO:0009250;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000011027.3|UniProtKB=G3R615 G3R615 C19H5orf22 PTHR13225:SF3 MISEXPRESSION SUPPRESSOR OF RAS 6 UPF0489 PROTEIN C5ORF22 GORGO|Ensembl=ENSGGOG00000036403.1|UniProtKB=G3QHF1 G3QHF1 OR2J3 PTHR26453:SF641 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2J3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011302.3|UniProtKB=G3R6Q2 G3R6Q2 EME1 PTHR21077:SF7 EME1 PROTEIN STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT EME1 regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;negative regulation of cell cycle phase transition#GO:1901988;meiosis I#GO:0007127;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;DNA-templated DNA replication#GO:0006261;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;organelle organization#GO:0006996;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;reproductive process#GO:0022414;homologous recombination#GO:0035825;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;DNA replication#GO:0006260;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;intracellular signal transduction#GO:0035556;organelle fission#GO:0048285;cell communication#GO:0007154;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;replication fork processing#GO:0031297;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;resolution of meiotic recombination intermediates#GO:0000712;DNA integrity checkpoint signaling#GO:0031570;mitotic cell cycle process#GO:1903047;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281 endonuclease complex#GO:1905348;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000010858.3|UniProtKB=G3R5K8 G3R5K8 COASY PTHR10695:SF60 DEPHOSPHO-COA KINASE-RELATED BIFUNCTIONAL COENZYME A SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;adenylyltransferase activity#GO:0070566;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006405.3|UniProtKB=A0A2I2Y6J8 A0A2I2Y6J8 ACVR1B PTHR23255:SF22 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1B transferase activity#GO:0016740;kinase activity#GO:0016301;activin binding#GO:0048185;signaling receptor activity#GO:0038023;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;molecular transducer activity#GO:0060089 multicellular organism development#GO:0007275;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;nervous system development#GO:0007399;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;activin receptor signaling pathway#GO:0032924;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;signaling receptor complex#GO:0043235;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Gonadotropin-releasing hormone receptor pathway#P06664>Alk4#P06845;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 GORGO|Ensembl=ENSGGOG00000006622.3|UniProtKB=G3QUR9 G3QUR9 RP2 PTHR15440:SF0 XRP2 PROTEIN PROTEIN XRP2 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 plasma membrane region#GO:0098590;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000005215.3|UniProtKB=G3QR73 G3QR73 ATP5PB PTHR12733:SF3 MITOCHONDRIAL ATP SYNTHASE B CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT B, MITOCHONDRIAL channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857 purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991 primary active transporter#PC00068;ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000015357.3|UniProtKB=G3RH63 G3RH63 TARDBP PTHR48033:SF9 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN TAR DNA-BINDING PROTEIN 43 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000011807.3|UniProtKB=G3R824 G3R824 TAF6L PTHR10221:SF22 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TAF6-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 6L structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;transcription by RNA polymerase II#GO:0006366;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;DNA-templated transcription initiation#GO:0006352;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-DNA complex assembly#GO:0065004;gene expression#GO:0010467;cellular component assembly#GO:0022607 SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;acetyltransferase complex#GO:1902493;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;peptidase complex#GO:1905368;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000010526.3|UniProtKB=G3R4Q6 G3R4Q6 LOC101126521 PTHR11984:SF33 CONNEXIN GAP JUNCTION ALPHA-1 PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cellular process#GO:0009987;regulation of biological process#GO:0050789;multicellular organismal process#GO:0032501;heart development#GO:0007507;circulatory system development#GO:0072359;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;animal organ development#GO:0048513;cell communication#GO:0007154;multicellular organism development#GO:0007275;system development#GO:0048731 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796 gap junction#PC00105;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000004079.3|UniProtKB=A0A2I2ZWA2 A0A2I2ZWA2 UBR2 PTHR21497:SF28 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR2 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000041643.1|UniProtKB=A0A2I2YWJ6 A0A2I2YWJ6 PTHR16501:SF12 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11 MITOCHONDRIAL FISSION FACTOR regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;protein localization to mitochondrion#GO:0070585;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;positive regulation of organelle organization#GO:0010638;localization#GO:0051179;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of developmental process#GO:0051094 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;peroxisome#GO:0005777;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;microbody#GO:0042579;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968 GORGO|Ensembl=ENSGGOG00000014646.3|UniProtKB=G3RFC1 G3RFC1 HS3ST2 PTHR10605:SF10 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000006139.3|UniProtKB=G3QTI2 G3QTI2 CST8 PTHR47010:SF1 CYSTATIN-8-RELATED CYSTATIN-8 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000003719.3|UniProtKB=G3QMC0 G3QMC0 ENOPH1 PTHR20371:SF1 ENOLASE-PHOSPHATASE E1 ENOLASE-PHOSPHATASE E1 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000005891.3|UniProtKB=G3QSW9 G3QSW9 RLN1 PTHR12004:SF14 RELAXIN PRORELAXIN H1 peptide hormone#PC00179;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000005823.3|UniProtKB=A0A2I2YW63 A0A2I2YW63 EPB41L5 PTHR23280:SF15 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 5 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of cell adhesion#GO:0045785;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789 leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;cell projection membrane#GO:0031253;ruffle#GO:0001726;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000025053.1|UniProtKB=G3S7Z8 G3S7Z8 ND4 PTHR43507:SF20 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;small molecule binding#GO:0036094;catalytic activity#GO:0003824;binding#GO:0005488 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;monoatomic ion transport#GO:0006811;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular respiration#GO:0045333;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000003238.3|UniProtKB=G3QL40 G3QL40 ASPG PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 GORGO|Ensembl=ENSGGOG00000004511.3|UniProtKB=G3QPC6 G3QPC6 RPTN PTHR14054:SF14 REPETIN REPETIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000037254.1|UniProtKB=A0A2I2YJ69 A0A2I2YJ69 PTHR47507:SF8 BARRIER TO AUTOINTEGRATION FACTOR 2 BAF NUCLEAR ASSEMBLY FACTOR 1 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793 GORGO|Ensembl=ENSGGOG00000005709.3|UniProtKB=G3QSF7 G3QSF7 PSMD5 PTHR13554:SF10 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5 protease#PC00190 GORGO|Ensembl=ENSGGOG00000016252.3|UniProtKB=A0A2I2Z3E1 A0A2I2Z3E1 ZFTRAF1 PTHR23059:SF4 CYSTEINE AND HISTIDINE-RICH PROTEIN 1 ZINC FINGER TRAF-TYPE-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000007464.3|UniProtKB=G3QWX8 G3QWX8 PLAC8 PTHR15907:SF32 DUF614 FAMILY PROTEIN-RELATED PLACENTA-SPECIFIC GENE 8 PROTEIN regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 GORGO|Ensembl=ENSGGOG00000014695.3|UniProtKB=G3RFH1 G3RFH1 PTHR21068:SF55 SPARTIN SPARTIN negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cell division#GO:0051301;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000016825.3|UniProtKB=G3RKZ4 G3RKZ4 NOS3 PTHR19384:SF66 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE 3 carbohydrate derivative binding#GO:0097367;monooxygenase activity#GO:0004497;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 response to external biotic stimulus#GO:0043207;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to bacterium#GO:0009617;circulatory system process#GO:0003013;biosynthetic process#GO:0009058;biological regulation#GO:0065007;amino acid metabolic process#GO:0006520;response to other organism#GO:0051707;blood circulation#GO:0008015;proteinogenic amino acid metabolic process#GO:0170039;multicellular organismal process#GO:0032501;carboxylic acid catabolic process#GO:0046395;regulation of blood pressure#GO:0008217;response to external stimulus#GO:0009605;system process#GO:0003008;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;regulation of biological quality#GO:0065008;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;arginine metabolic process#GO:0006525;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;response to lipid#GO:0033993;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;response to lipopolysaccharide#GO:0032496;metabolic process#GO:0008152 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Angiogenesis#P00005>eNOS#P00210;Endothelin signaling pathway#P00019>eNOS#P00578;PI3 kinase pathway#P00048>NOS#P01205;VEGF signaling pathway#P00056>eNOS#P01422;Interleukin signaling pathway#P00036>eNOS#P00986 GORGO|Ensembl=ENSGGOG00000043266.1|UniProtKB=A0A2I2Y2J2 A0A2I2Y2J2 PTHR23266:SF366 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008891.3|UniProtKB=A0A2I2YQX4 A0A2I2YQX4 PTAR1 PTHR11129:SF3 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000012721.3|UniProtKB=G3RAD6 G3RAD6 DFFA PTHR12306:SF16 CELL DEATH ACTIVATOR CIDE DNAATION FACTOR SUBUNIT ALPHA transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013 lipid droplet organization#GO:0034389;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of catabolic process#GO:0009895;cellular component organization#GO:0016043;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;cellular component organization or biogenesis#GO:0071840;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;cellular process#GO:0009987;lipid storage#GO:0019915;negative regulation of programmed cell death#GO:0043069;negative regulation of macromolecule metabolic process#GO:0010605;organelle fusion#GO:0048284;negative regulation of apoptotic process#GO:0043066;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007 chromosome#GO:0005694;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000014805.3|UniProtKB=A0A2I2YGI9 A0A2I2YGI9 HMG20B PTHR46040:SF2 HIGH MOBILITY GROUP PROTEIN 2 SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1-RELATED regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000007916.3|UniProtKB=G3QY24 G3QY24 ATIC PTHR11692:SF0 BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate biosynthetic process#GO:1901293 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 De novo purine biosynthesis#P02738>AICAR transformylase#P02900;De novo purine biosynthesis#P02738>IMP cyclohydrolase#P02894 GORGO|Ensembl=ENSGGOG00000022136.2|UniProtKB=G3RZ18 G3RZ18 RIOK2 PTHR45852:SF1 SER/THR-PROTEIN KINASE RIO2 SERINE_THREONINE-PROTEIN KINASE RIO2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000044110.1|UniProtKB=A0A2I2ZW58 A0A2I2ZW58 PTHR10373:SF32 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7-LIKE 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;regulation of cell communication#GO:0010646;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of DNA-templated transcription#GO:0006355;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of carbohydrate metabolic process#GO:0006109;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;cell surface receptor signaling pathway#GO:0007166 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575;chromatin#GO:0000785;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Angiogenesis#P00005>TCF#P00242;Cadherin signaling pathway#P00012>TCF/LEF#P00465 GORGO|Ensembl=ENSGGOG00000009080.3|UniProtKB=G3SG02 G3SG02 ZNF736 PTHR24381:SF404 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 736 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022392.2|UniProtKB=G3RTD2 G3RTD2 SNAPC2 PTHR15132:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 2 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 GORGO|Ensembl=ENSGGOG00000005966.3|UniProtKB=G3QT30 G3QT30 MRPS14 PTHR19836:SF31 30S RIBOSOMAL PROTEIN S14 SMALL RIBOSOMAL SUBUNIT PROTEIN US14M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025230.2|UniProtKB=A0A2I2ZDA9 A0A2I2ZDA9 LOC109026017 PTHR18860:SF88 14-3-3 PROTEIN 14-3-3 DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004843.3|UniProtKB=G3QQ84 G3QQ84 ZBTB41 PTHR24376:SF275 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 41 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000037469.1|UniProtKB=A0A2I2ZXW2 A0A2I2ZXW2 LOC101145465 PTHR10502:SF18 ANNEXIN ANNEXIN A2-RELATED anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phospholipid binding#GO:0005543;ion binding#GO:0043167;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;cell adhesion#GO:0007155;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of proteolysis#GO:0030162;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000006080.3|UniProtKB=G3QTD9 G3QTD9 MCM4 PTHR11630:SF66 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM4 helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697 DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cell cycle process#GO:0022402;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitotic cell cycle process#GO:1903047;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;DNA damage response#GO:0006974;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;DNA repair#GO:0006281;mitotic DNA replication#GO:1902969;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;MCM complex#GO:0042555;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000040395.1|UniProtKB=A0A2I2YL63 A0A2I2YL63 ZNF761 PTHR23232:SF178 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN 5-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010949.3|UniProtKB=G3R5U7 G3R5U7 SPAG1 PTHR45984:SF3 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG SPERM-ASSOCIATED ANTIGEN 1 protein binding#GO:0005515;binding#GO:0005488;heat shock protein binding#GO:0031072 macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000314.3|UniProtKB=G3QDI9 G3QDI9 ABCF2 PTHR19211:SF15 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2 ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ATP binding#GO:0005524;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000000807.3|UniProtKB=A0A2I2Z804 A0A2I2Z804 LOC101133975 PTHR12138:SF164 PRIMATE-EXPANDED PROTEIN FAMILY SECRETED PROTEIN GORGO|Ensembl=ENSGGOG00000005843.3|UniProtKB=G3QSS8 G3QSS8 SLC25A39 PTHR45760:SF1 FI19922P1-RELATED MITOCHONDRIAL GLUTATHIONE TRANSPORTER SLC25A39 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000009242.3|UniProtKB=G3R1G6 G3R1G6 ZZZ3 PTHR22705:SF0 ZINC FINGER, ZZ DOMAIN CONTAINING 3 ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000012338.3|UniProtKB=G3R9G3 G3R9G3 PTHR23159:SF14 CENTROSOMAL PROTEIN 2 TESTIS-SPECIFIC GENE 10 PROTEIN organelle assembly#GO:0070925;centriole replication#GO:0007099;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000002852.3|UniProtKB=G3QK44 G3QK44 EDEM3 PTHR45679:SF2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;carbohydrate derivative metabolic process#GO:1901135;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;protein catabolic process#GO:0030163;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;glycoprotein metabolic process#GO:0009100;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000002818.3|UniProtKB=G3QK15 G3QK15 RPS15 PTHR11880:SF28 RIBOSOMAL PROTEIN S19P FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US19 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005169.3|UniProtKB=G3QR32 G3QR32 BICDL2 PTHR32123:SF11 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 2 establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;vesicle cytoskeletal trafficking#GO:0099518;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle localization#GO:0051640 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000016399.3|UniProtKB=G3RJV9 G3RJV9 RAPH1 PTHR11243:SF15 GROWTH FACTOR RECEPTOR-BOUND PROTEIN RAS-ASSOCIATED AND PLECKSTRIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell morphogenesis#GO:0000902;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell projection organization#GO:0030030 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005923.3|UniProtKB=G3SFP8 G3SFP8 DCAF12L2 PTHR19860:SF8 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 12-LIKE PROTEIN 2 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000006535.3|UniProtKB=G3QUI9 G3QUI9 ZNF222 PTHR24381:SF428 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 234 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000005664.3|UniProtKB=A0A2I2YFF6 A0A2I2YFF6 PTHR36961:SF1 LEUKEMIA-ASSOCIATED PROTEIN 7 LEUKEMIA-ASSOCIATED PROTEIN 7 GORGO|Ensembl=ENSGGOG00000013450.3|UniProtKB=G3RC93 G3RC93 SLC1A6 PTHR11958:SF67 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 4 neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;sodium ion transmembrane transporter activity#GO:0015081;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324 carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;L-glutamate import#GO:0051938;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;acidic amino acid transport#GO:0015800;carboxylic acid transport#GO:0046942 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 GORGO|Ensembl=ENSGGOG00000016685.3|UniProtKB=G3RUC2 G3RUC2 TIGD1 PTHR19303:SF26 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 1 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000014406.3|UniProtKB=G3SA18 G3SA18 SELENOO PTHR12153:SF15 SELENOPROTEIN O PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL GORGO|Ensembl=ENSGGOG00000000478.3|UniProtKB=G3RMT0 G3RMT0 PTHR14167:SF45 SH3 DOMAIN-CONTAINING ENDOPHILIN-A3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cytoplasm#GO:0005737;cytosol#GO:0005829;presynapse#GO:0098793;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Huntington disease#P00029>SH3GL3#P00813 GORGO|Ensembl=ENSGGOG00000012796.3|UniProtKB=A0A2I2YYX6 A0A2I2YYX6 SYF2 PTHR13264:SF5 GCIP-INTERACTING PROTEIN P29 PRE-MRNA-SPLICING FACTOR SYF2 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000024426.2|UniProtKB=G3S175 G3S175 COX5A PTHR14200:SF18 CYTOCHROME C OXIDASE POLYPEPTIDE CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494 oxidase#PC00175;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007044.3|UniProtKB=A0A2I2YM82 A0A2I2YM82 LOC101126372 PTHR24280:SF4 CYTOCHROME P450 20A1 CYTOCHROME P450 20A1 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000012919.3|UniProtKB=G3RAW9 G3RAW9 PTHR24205:SF3 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 2 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of calcineurin-NFAT signaling cascade#GO:0070884;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000012953.3|UniProtKB=G3RB03 G3RB03 STRA8 PTHR35254:SF1 STIMULATED BY RETINOIC ACID GENE 8 PROTEIN HOMOLOG STIMULATED BY RETINOIC ACID GENE 8 PROTEIN HOMOLOG GORGO|Ensembl=ENSGGOG00000010725.3|UniProtKB=G3R5A1 G3R5A1 LAMB1 PTHR10574:SF233 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-1 binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178 axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;cell-substrate adhesion#GO:0031589;system development#GO:0048731;external encapsulating structure organization#GO:0045229;cell motility#GO:0048870;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;extracellular matrix assembly#GO:0085029;tissue development#GO:0009888;cell migration#GO:0016477;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;basement membrane#GO:0005604;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000006111.3|UniProtKB=A0A2I2ZFN4 A0A2I2ZFN4 C4H5orf63 PTHR33558:SF2 GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG GLUTAREDOXIN-LIKE PROTEIN C5ORF63 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000023963.2|UniProtKB=G3S9E3 G3S9E3 PTHR24327:SF67 HOMEOBOX PROTEIN HOMEOBOX DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;stem cell population maintenance#GO:0019827;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;maintenance of cell number#GO:0098727;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000000672.3|UniProtKB=G3QEG7 G3QEG7 PRLHR PTHR24235:SF11 NEUROPEPTIDE Y RECEPTOR PROLACTIN-RELEASING PEPTIDE RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;feeding behavior#GO:0007631 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007266.3|UniProtKB=A0A2I2YFU1 A0A2I2YFU1 PIAS3 PTHR10782:SF10 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS3 ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;post-translational protein modification#GO:0043687;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signaling#GO:0023051;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;metabolic process#GO:0008152;protein sumoylation#GO:0016925;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968 membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 GORGO|Ensembl=ENSGGOG00000040829.1|UniProtKB=A0A2I2ZPS2 A0A2I2ZPS2 PTHR11913:SF70 COFILIN-RELATED ADF-H DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;protein depolymerization#GO:0051261;cytoskeleton organization#GO:0007010;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cellular component disassembly#GO:0022411;cytoskeleton-dependent cytokinesis#GO:0061640;actin filament-based process#GO:0030029;cytokinesis#GO:0000910;protein-containing complex disassembly#GO:0032984;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cell division#GO:0051301;cellular component organization#GO:0016043;cell cycle#GO:0007049 actin cytoskeleton#GO:0015629;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000022632.2|UniProtKB=G3S8P0 G3S8P0 PTHR10956:SF31 60S RIBOSOMAL PROTEIN L31 LARGE RIBOSOMAL SUBUNIT PROTEIN EL31 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000010057.3|UniProtKB=G3R3L1 G3R3L1 SMG1 PTHR11139:SF71 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE SMG1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;cellular process#GO:0009987;response to stress#GO:0006950;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;RNA catabolic process#GO:0006401;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011808.3|UniProtKB=G3R818 G3R818 SPEM1 PTHR34834:SF1 SPERMATID MATURATION PROTEIN 1 SPERMATID MATURATION PROTEIN 1 cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;multicellular organismal process#GO:0032501;male gamete generation#GO:0048232;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;sperm motility#GO:0097722;anatomical structure morphogenesis#GO:0009653;microtubule-based movement#GO:0007018;gamete generation#GO:0007276;cell motility#GO:0048870;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285;multicellular organismal reproductive process#GO:0048609 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000001068.3|UniProtKB=G3QFH9 G3QFH9 RGS1 PTHR10845:SF34 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 1 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 GORGO|Ensembl=ENSGGOG00000006073.3|UniProtKB=A0A2I2YZ12 A0A2I2YZ12 TUB PTHR16517:SF20 TUBBY-RELATED TUBBY PROTEIN HOMOLOG macromolecule localization#GO:0033036;localization#GO:0051179;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104 cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005045.3|UniProtKB=G3QQR8 G3QQR8 GADD45G PTHR10411:SF4 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 p53 pathway#P00059>GADD45#G01575;p53 pathway#P00059>GADD45#P04626 GORGO|Ensembl=ENSGGOG00000040915.1|UniProtKB=A0A2I2YYT0 A0A2I2YYT0 TP53I3 PTHR48106:SF18 QUINONE OXIDOREDUCTASE PIG3-RELATED QUINONE OXIDOREDUCTASE PIG3 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 GORGO|Ensembl=ENSGGOG00000022851.2|UniProtKB=G3SBT9 G3SBT9 PARP16 PTHR21328:SF2 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP16 molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539 biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976 nucleus#GO:0005634;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000002780.3|UniProtKB=G3QJX8 G3QJX8 KLHL34 PTHR45632:SF8 LD33804P KELCH-LIKE PROTEIN 34 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005010.3|UniProtKB=G3QQP3 G3QQP3 PTHR21663:SF2 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5B retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000022432.3|UniProtKB=G3RZ27 G3RZ27 CHODL PTHR14789:SF1 CHONDROLECTIN VARIANT CHODLFDELTAE. CHONDROLECTIN positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;regulation of axonogenesis#GO:0050770;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cell development#GO:0060284;biological regulation#GO:0065007;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;positive regulation of axonogenesis#GO:0050772;regulation of nervous system development#GO:0051960;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012893.3|UniProtKB=A0A2I2YMQ5 A0A2I2YMQ5 NDRG3 PTHR11034:SF20 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG3 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000008529.3|UniProtKB=G3QZN1 G3QZN1 GLP2R PTHR45620:SF23 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON-LIKE PEPTIDE 2 RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008268.3|UniProtKB=G3QYY3 G3QYY3 HEYL PTHR10985:SF79 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF-LIKE PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;pattern specification process#GO:0007389;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cell surface receptor signaling pathway#GO:0007166;anterior/posterior pattern specification#GO:0009952 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 GORGO|Ensembl=ENSGGOG00000025029.2|UniProtKB=G3S7S4 G3S7S4 CDIP1 PTHR23292:SF7 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR CELL DEATH-INDUCING P53-TARGET PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;intracellular signal transduction#GO:0035556;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;regulation of cellular process#GO:0050794;signaling#GO:0023052;programmed cell death#GO:0012501;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;regulation of biological process#GO:0050789;cell death#GO:0008219;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;biological regulation#GO:0065007;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987 cytoplasm#GO:0005737;vacuole#GO:0005773;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;nucleus#GO:0005634;lysosomal membrane#GO:0005765;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasmic side of membrane#GO:0098562;late endosome membrane#GO:0031902;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004798.3|UniProtKB=G3QQ45 G3QQ45 LOXL4 PTHR45817:SF5 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 4 oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000012472.3|UniProtKB=A0A2I2ZHN3 A0A2I2ZHN3 COMMD9 PTHR15663:SF4 COMM DOMAIN-CONTAINING PROTEIN 9 COMM DOMAIN-CONTAINING PROTEIN 9 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000016204.3|UniProtKB=G3S3M7 G3S3M7 DEF6 PTHR14383:SF2 SWAP-70 RECOMBINASE DIFFERENTIALLY EXPRESSED IN FDCP 6 HOMOLOG molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component assembly#GO:0022607;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;small GTPase-mediated signal transduction#GO:0007264;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000024229.2|UniProtKB=G3QSV7 G3QSV7 LOC101124572 PTHR23299:SF18 METALLOTHIONEIN METALLOTHIONEIN-3 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 inorganic ion homeostasis#GO:0098771;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;response to stimulus#GO:0050896;chemical homeostasis#GO:0048878;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;detoxification of inorganic compound#GO:0061687;monoatomic ion homeostasis#GO:0050801;detoxification#GO:0098754;regulation of ERK1 and ERK2 cascade#GO:0070372;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to toxic substance#GO:0009636;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;response to metal ion#GO:0010038;response to cadmium ion#GO:0046686;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000005315.3|UniProtKB=G3QRF1 G3QRF1 NEXMIF PTHR46946:SF1 NEURITE EXTENSION AND MIGRATION FACTOR NEURITE EXTENSION AND MIGRATION FACTOR regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of cell-matrix adhesion#GO:0001952;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;negative regulation of cell motility#GO:2000146;regulation of cell adhesion#GO:0030155;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of cell adhesion#GO:0007162;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of neuron migration#GO:2001222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012944.3|UniProtKB=G3RAZ7 G3RAZ7 PNISR PTHR31518:SF3 ARGININE/SERINE-RICH PROTEIN PNISR ARGININE_SERINE-RICH PROTEIN PNISR GORGO|Ensembl=ENSGGOG00000025385.2|UniProtKB=G3SC76 G3SC76 SLC19A2 PTHR10686:SF19 FOLATE TRANSPORTER THIAMINE TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;vitamin transport#GO:0051180 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007752.3|UniProtKB=G3QXN3 G3QXN3 PTHR11328:SF30 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN SPHINGOSINE-1-PHOSPHATE TRANSPORTER MFSD2B transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303 cellular process#GO:0009987;macromolecule localization#GO:0033036;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000002681.3|UniProtKB=A0A2I2YSZ9 A0A2I2YSZ9 PTHR10722:SF48 60S RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN EL19 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000037622.1|UniProtKB=A0A2I2ZX24 A0A2I2ZX24 SOX11 PTHR10270:SF113 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-11 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837 multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of macromolecule metabolic process#GO:0010604;head development#GO:0060322;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;sensory organ morphogenesis#GO:0090596;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;camera-type eye morphogenesis#GO:0048593;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;camera-type eye development#GO:0043010;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000038343.1|UniProtKB=A0A2I2Z7A5 A0A2I2Z7A5 LOC101147356 PTHR47010:SF2 CYSTATIN-8-RELATED CYSTATIN-13 GORGO|Ensembl=ENSGGOG00000003069.3|UniProtKB=A0A2I2ZGR5 A0A2I2ZGR5 WDR11 PTHR14593:SF5 WD REPEAT-CONTAINING PROTEIN 11 WD REPEAT-CONTAINING PROTEIN 11 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000004406.3|UniProtKB=A0A2I2YSM3 A0A2I2YSM3 CCNY PTHR14248:SF33 CYCLIN Y, ISOFORM A CYCLIN-Y molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000008156.3|UniProtKB=A0A2I2YQS9 A0A2I2YQS9 R3HDM1 PTHR15672:SF12 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN R3H DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000034894.2|UniProtKB=A0A2I2YWC2 A0A2I2YWC2 VEPH1 PTHR21630:SF10 VEPH-A/MELTED VENTRICULAR ZONE-EXPRESSED PH DOMAIN-CONTAINING PROTEIN HOMOLOG 1 phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000000046.3|UniProtKB=G3SDI4 G3SDI4 GKN2 PTHR16483:SF3 GASTROKINE 1 GASTROKINE-2 regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014410.3|UniProtKB=A0A2I2ZW51 A0A2I2ZW51 ST7 PTHR12745:SF8 SUPPRESSION OF TUMORIGENICITY 7 SUPPRESSOR OF TUMORIGENICITY 7 PROTEIN GORGO|Ensembl=ENSGGOG00000014674.3|UniProtKB=G3RFF0 G3RFF0 IL2RG PTHR23036:SF172 CYTOKINE RECEPTOR CYTOKINE RECEPTOR COMMON SUBUNIT GAMMA signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;coreceptor activity#GO:0015026;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cellular process#GO:0050794;interleukin-2-mediated signaling pathway#GO:0038110;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;cell communication#GO:0007154;anatomical structure development#GO:0048856;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;interleukin-15-mediated signaling pathway#GO:0035723;interleukin-9-mediated signaling pathway#GO:0038113;response to cytokine#GO:0034097;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;signal transduction#GO:0007165;cellular process#GO:0009987;interleukin-7-mediated signaling pathway#GO:0038111;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;mononuclear cell differentiation#GO:1903131;leukocyte differentiation#GO:0002521;response to peptide#GO:1901652;immune system process#GO:0002376 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000041456.1|UniProtKB=A0A2I2YKA0 A0A2I2YKA0 CENPP PTHR28577:SF1 CENTROMERE PROTEIN P CENTROMERE PROTEIN P organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000015526.3|UniProtKB=G3RHM4 G3RHM4 SLC16A1 PTHR11360:SF24 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 1 monoatomic cation transmembrane transporter activity#GO:0008324;solute:proton symporter activity#GO:0015295;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;monocarboxylic acid transmembrane transporter activity#GO:0008028;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015364.3|UniProtKB=G3RYA3 G3RYA3 WDR1 PTHR19856:SF8 WD-REPEATCONTAINING PROTEIN WDR1 WD REPEAT-CONTAINING PROTEIN 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 actin polymerization or depolymerization#GO:0008154;protein depolymerization#GO:0051261;developmental process#GO:0032502;cellular developmental process#GO:0048869;actin filament organization#GO:0007015;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;protein-containing complex disassembly#GO:0032984;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;animal gross anatomical part developmental process#GO:0160108;cellular component disassembly#GO:0022411;striated muscle cell development#GO:0055002 actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000013110.3|UniProtKB=A0A2I2ZWF3 A0A2I2ZWF3 LPIN3 PTHR12181:SF62 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN3 hydrolase activity#GO:0016787;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824 response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;lipid catabolic process#GO:0016042;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;small molecule catabolic process#GO:0044282;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;fatty acid catabolic process#GO:0009062;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;glycerolipid biosynthetic process#GO:0045017;positive regulation of cellular process#GO:0048522;carboxylic acid catabolic process#GO:0046395;positive regulation of DNA-templated transcription#GO:0045893;cellular response to nitrogen compound#GO:1901699;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;triglyceride biosynthetic process#GO:0019432;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to peptide hormone#GO:0043434;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;acylglycerol metabolic process#GO:0006639;fatty acid metabolic process#GO:0006631;cellular response to insulin stimulus#GO:0032869;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;regulation of biosynthetic process#GO:0009889;neutral lipid metabolic process#GO:0006638;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;cellular response to peptide hormone stimulus#GO:0071375;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000015349.3|UniProtKB=G3RH57 G3RH57 RASSF3 PTHR22738:SF8 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 3 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025090.2|UniProtKB=G3S0R6 G3S0R6 PTHR23120:SF40 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 6 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004899.3|UniProtKB=A0A2I2ZX48 A0A2I2ZX48 MS4A12 PTHR23320:SF72 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 12 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004398.3|UniProtKB=G3S8M4 G3S8M4 DLX6 PTHR24327:SF26 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;skeletal system development#GO:0001501;embryo development ending in birth or egg hatching#GO:0009792;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000010202.3|UniProtKB=A0A2I2YYB6 A0A2I2YYB6 GSN PTHR11977:SF29 VILLIN GELSOLIN lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543 regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular component biogenesis#GO:0044085;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;regulation of actin cytoskeleton organization#GO:0032956;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;central nervous system development#GO:0007417;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;multicellular organismal process#GO:0032501;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;negative regulation of cytoskeleton organization#GO:0051494;anatomical structure development#GO:0048856;negative regulation of protein-containing complex disassembly#GO:0043242;system development#GO:0048731;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 FAS signaling pathway#P00020>Gelsolin#P00611 GORGO|Ensembl=ENSGGOG00000011554.3|UniProtKB=G3R7D4 G3R7D4 THY1 PTHR19226:SF2 THY-1 MEMBRANE GLYCOPROTEIN THY-1 MEMBRANE GLYCOPROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell adhesion#GO:0030155;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;positive regulation of cellular component organization#GO:0051130;regulation of cell junction assembly#GO:1901888;regulation of cell-matrix adhesion#GO:0001952;cell communication#GO:0007154 cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;membrane raft#GO:0045121;side of membrane#GO:0098552;dendritic tree#GO:0097447;external side of plasma membrane#GO:0009897;membrane microdomain#GO:0098857;dendrite#GO:0030425 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000014968.3|UniProtKB=A0A2I2YWM6 A0A2I2YWM6 MYEF2 PTHR23003:SF15 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN MYELIN EXPRESSION FACTOR 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nuclear mRNA surveillance#GO:0071028;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000006947.3|UniProtKB=G3QVL8 G3QVL8 PRDM13 PTHR16515:SF21 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 13 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008452.3|UniProtKB=G3QZF2 G3QZF2 CCNE1 PTHR10177:SF71 CYCLINS G1_S-SPECIFIC CYCLIN-E1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell cycle G1/S phase transition#GO:0044843;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554 kinase activator#PC00138 p53 pathway#P00059>Cyclin E#P04610;Cell cycle#P00013>Cyclin E#P00483;Cell cycle#P00013>CdkC#P00489;p53 pathway feedback loops 2#P04398>cyclin E#P04664;Parkinson disease#P00049>Cyclin E#P01213 GORGO|Ensembl=ENSGGOG00000014294.3|UniProtKB=G3REF7 G3REF7 GAL3ST2 PTHR14647:SF55 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 2 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004723.3|UniProtKB=A0A2I2ZLW9 A0A2I2ZLW9 POLR2D PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 GORGO|Ensembl=ENSGGOG00000026908.2|UniProtKB=G3SJZ7 G3SJZ7 NEUROD6 PTHR19290:SF9 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 6 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000016636.3|UniProtKB=G3SJY5 G3SJY5 OPN5 PTHR24240:SF0 OPSIN OPSIN-5 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;biological regulation#GO:0065007;detection of stimulus#GO:0051606;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;response to radiation#GO:0009314;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016280.3|UniProtKB=A0A2I2YZ93 A0A2I2YZ93 NEDD9 PTHR10654:SF20 CAS SCAFFOLDING PROTEIN ENHANCER OF FILAMENTATION 1 signaling#GO:0023052;biological regulation#GO:0065007;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000037797.1|UniProtKB=A0A2I2ZTT6 A0A2I2ZTT6 PTHR12483:SF95 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS COPPER TRANSPORT PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;copper ion transmembrane transport#GO:0035434;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012958.3|UniProtKB=G3RB13 G3RB13 EML1 PTHR13720:SF22 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000028598.2|UniProtKB=G3S847 G3S847 ARV1 PTHR14467:SF0 ARV1 PROTEIN ARV1 glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000008850.3|UniProtKB=A0A2I2YW55 A0A2I2YW55 CRBN PTHR14255:SF4 CEREBLON PROTEIN CEREBLON enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;catabolic process#GO:0009056;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967 nucleus#GO:0005634;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002756.3|UniProtKB=G3QJW3 G3QJW3 LIMD1 PTHR24219:SF3 LIM DOMAIN-CONTAINING PROTEIN JUB LIM DOMAIN-CONTAINING PROTEIN 1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of response to stimulus#GO:0048583;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;negative regulation of signal transduction#GO:0009968;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of hippo signaling#GO:0035330;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of translation#GO:0017148 adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;nucleus#GO:0005634;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000004522.3|UniProtKB=G3QPE5 G3QPE5 DNAI1 PTHR12442:SF11 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 1 binding#GO:0005488;protein binding#GO:0005515 microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium movement#GO:0003341;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;plasma membrane bounded cell projection assembly#GO:0120031 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;catalytic complex#GO:1902494;cilium#GO:0005929;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;axonemal dynein complex#GO:0005858;membraneless organelle#GO:0043228;outer dynein arm#GO:0036157;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000014370.3|UniProtKB=G3REM4 G3REM4 HEXIM1 PTHR13469:SF7 HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 PROTEIN HEXIM1 molecular function inhibitor activity#GO:0140678;RNA binding#GO:0003723;enzyme regulator activity#GO:0030234;snRNA binding#GO:0017069;nucleic acid binding#GO:0003676;binding#GO:0005488;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002784.3|UniProtKB=G3QJY6 G3QJY6 MCCC1 PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;ligase#PC00142 GORGO|Ensembl=ENSGGOG00000013747.3|UniProtKB=G3RD22 G3RD22 LOC101133928 PTHR11232:SF76 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CARBOXYL-TERMINAL PDZ LIGAND OF NEURONAL NITRIC OXIDE SYNTHASE PROTEIN signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016272.3|UniProtKB=G3SHJ7 G3SHJ7 PTPN12 PTHR45983:SF3 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 12 hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 Integrin signalling pathway#P00034>PTP-PEST#P00915 GORGO|Ensembl=ENSGGOG00000028229.2|UniProtKB=A0A2I2Z9S4 A0A2I2Z9S4 PDCD2 PTHR12298:SF8 PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED US5 ASSEMBLY CHAPERONE PDCD2 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000001584.3|UniProtKB=G3QGU6 G3QGU6 HEBP2 PTHR11220:SF70 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 2 heme binding#GO:0020037;binding#GO:0005488;tetrapyrrole binding#GO:0046906 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000536.3|UniProtKB=G3QE42 G3QE42 SLC66A1 PTHR16201:SF36 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED LYSOSOMAL AMINO ACID TRANSPORTER 1 HOMOLOG transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;aromatic amino acid transmembrane transporter activity#GO:0015173;basic amino acid transmembrane transporter activity#GO:0015174 chemical homeostasis#GO:0048878;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;vacuolar transmembrane transport#GO:0034486;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;homeostatic process#GO:0042592 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 GORGO|Ensembl=ENSGGOG00000012039.3|UniProtKB=G3R8M7 G3R8M7 ANKRD46 PTHR24171:SF13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 46 ISOFORM X1 GORGO|Ensembl=ENSGGOG00000013267.3|UniProtKB=G3RBS7 G3RBS7 HIBADH PTHR22981:SF85 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED 3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000014330.3|UniProtKB=G3REJ8 G3REJ8 GUCY2D PTHR11920:SF228 GUANYLYL CYCLASE RETINAL GUANYLYL CYCLASE 1 guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;molecular transducer activity#GO:0060089;lyase activity#GO:0016829 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190 organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 guanylate cyclase#PC00114;lyase#PC00144 CCKR signaling map#P06959>Guanylate cyclase#P07116 GORGO|Ensembl=ENSGGOG00000027537.2|UniProtKB=G3RPU5 G3RPU5 PTHR19375:SF396 HEAT SHOCK PROTEIN 70KDA ENDOPLASMIC RETICULUM CHAPERONE BIP ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 macromolecule biosynthetic process#GO:0009059;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007;biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;gene expression#GO:0010467;protein maturation#GO:0051604;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biological process#GO:0050789;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein refolding#GO:0042026;response to unfolded protein#GO:0006986 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783 chaperone#PC00072;Hsp70 family chaperone#PC00027 GORGO|Ensembl=ENSGGOG00000014431.3|UniProtKB=G3RWH0 G3RWH0 LOC101137843 PTHR24381:SF417 ZINC FINGER PROTEIN AA987161 PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003186.3|UniProtKB=A0A2I2ZGH3 A0A2I2ZGH3 ZEB2 PTHR24391:SF11 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER E-BOX-BINDING HOMEOBOX 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000008411.3|UniProtKB=A0A2I2YMC6 A0A2I2YMC6 LRRFIP1 PTHR19212:SF5 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000010194.3|UniProtKB=G3R3V9 G3R3V9 SOCS2 PTHR10155:SF7 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 2 signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;protein binding#GO:0005515 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to peptide#GO:1901652;negative regulation of cell communication#GO:0010648;cytokine-mediated signaling pathway#GO:0019221;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;response to chemical#GO:0042221;response to cytokine#GO:0034097;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523;cell surface receptor signaling pathway#GO:0007166;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 GORGO|Ensembl=ENSGGOG00000036563.1|UniProtKB=G3RB30 G3RB30 GSTM5 PTHR11571:SF249 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 5 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364 glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000016758.3|UniProtKB=G3RKS7 G3RKS7 SMARCC1 PTHR12802:SF9 SWI/SNF COMPLEX-RELATED SWI_SNF COMPLEX SUBUNIT SMARCC1 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000003222.3|UniProtKB=A0A2I2ZPR1 A0A2I2ZPR1 NR1D2 PTHR24082:SF112 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 2 transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;sequence-specific double-stranded DNA binding#GO:1990837 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000013521.3|UniProtKB=G3RCF9 G3RCF9 AKIP1 PTHR14330:SF2 A-KINASE-INTERACTING PROTEIN 1 A-KINASE-INTERACTING PROTEIN 1 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000041162.1|UniProtKB=A0A2I2ZAV3 A0A2I2ZAV3 PTHR24377:SF960 IP01015P-RELATED ZINC FINGER PROTEIN 181 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006249.3|UniProtKB=G3SAX2 G3SAX2 CCNL1 PTHR10026:SF64 CYCLIN CYCLIN-L1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase modulator#PC00140;kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000007890.3|UniProtKB=G3QXZ8 G3QXZ8 LOC101147918 PTHR11461:SF165 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-1-ANTITRYPSIN enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Blood coagulation#P00011>alpha1-antitrypsin#P00421 GORGO|Ensembl=ENSGGOG00000012576.3|UniProtKB=G3RA20 G3RA20 SPTLC3 PTHR13693:SF56 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 3 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;ceramide biosynthetic process#GO:0046513;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991 transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000012868.3|UniProtKB=G3RAS8 G3RAS8 SMOC2 PTHR12352:SF21 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 2 heparin binding#GO:0008201;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;extracellular matrix binding#GO:0050840 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000028176.2|UniProtKB=A0A2I2ZKC1 A0A2I2ZKC1 LOC109023100 PTHR48002:SF4 OLFACTORY RECEPTOR OLFACTORY RECEPTOR-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025876.2|UniProtKB=A0A2K5TIZ7 A0A2K5TIZ7 TOPAZ1 PTHR35671:SF1 PROTEIN TOPAZ1 PROTEIN TOPAZ1 developmental process involved in reproduction#GO:0003006;cell division#GO:0051301;cellular process#GO:0009987;gamete generation#GO:0007276;male gamete generation#GO:0048232;reproductive process#GO:0022414;developmental process#GO:0032502;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609 GORGO|Ensembl=ENSGGOG00000004785.3|UniProtKB=G3QQ28 G3QQ28 CXCR6 PTHR10489:SF705 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 6 cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;chemotaxis#GO:0006935;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000015326.3|UniProtKB=G3RH37 G3RH37 MTHFD2L PTHR48099:SF7 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE 2, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760 cytosol#GO:0005829;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 GORGO|Ensembl=ENSGGOG00000010122.3|UniProtKB=G3R3P9 G3R3P9 DUSP11 PTHR10367:SF18 MRNA-CAPPING ENZYME RNA_RNP COMPLEX-1-INTERACTING PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 RNA processing factor#PC00147;mRNA capping factor#PC00145 GORGO|Ensembl=ENSGGOG00000005732.3|UniProtKB=G3QSI1 G3QSI1 ITIH3 PTHR10338:SF115 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H3 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000008864.3|UniProtKB=G3R0H6 G3R0H6 LRFN2 PTHR24366:SF48 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 2B immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000023345.2|UniProtKB=A0A2I2YYA0 A0A2I2YYA0 PTHR11721:SF34 60S RIBOSOMAL PROTEIN L27A LARGE RIBOSOMAL SUBUNIT PROTEIN UL15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000024494.2|UniProtKB=A0A2I2Z8W5 A0A2I2Z8W5 CREBL2 PTHR21051:SF4 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000044057.1|UniProtKB=A0A2I2Y2W7 A0A2I2Y2W7 PTHR13817:SF16 TITIN MYOMESIN-1 structural molecule activity#GO:0005198;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856 contractile muscle fiber#GO:0043292;A band#GO:0031672;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;M band#GO:0031430;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000003804.3|UniProtKB=G3RNI2 G3RNI2 CBL PTHR23007:SF5 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL acyltransferase activity#GO:0016746;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;receptor tyrosine kinase binding#GO:0030971;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;transferase activity#GO:0016740 regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 membrane#GO:0016020;membrane raft#GO:0045121;membrane microdomain#GO:0098857;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 GORGO|Ensembl=ENSGGOG00000036777.1|UniProtKB=A0A2I2YTK7 A0A2I2YTK7 PTHR11426:SF242 HISTONE H3 HISTONE H3.1 cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic cell cycle#GO:0000278;organelle assembly#GO:0070925;organelle localization#GO:0051640;nuclear division#GO:0000280;kinetochore assembly#GO:0051382;localization#GO:0051179;kinetochore organization#GO:0051383;organelle fission#GO:0048285;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 GORGO|Ensembl=ENSGGOG00000010362.3|UniProtKB=G3R4E3 G3R4E3 ATM PTHR11139:SF130 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE-PROTEIN KINASE ATM phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to radiation#GO:0071478;signaling#GO:0023052;response to ionizing radiation#GO:0010212;regulation of DNA metabolic process#GO:0051052;positive regulation of metabolic process#GO:0009893;positive regulation of organelle organization#GO:0010638;negative regulation of intracellular signal transduction#GO:1902532;intrinsic apoptotic signaling pathway#GO:0097193;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component organization#GO:0051130;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;regulation of telomere maintenance via telomere lengthening#GO:1904356;response to stress#GO:0006950;regulation of TOR signaling#GO:0032006;double-strand break repair#GO:0006302;metabolic process#GO:0008152;negative regulation of TORC1 signaling#GO:1904262;negative regulation of TOR signaling#GO:0032007;cellular response to environmental stimulus#GO:0104004;nucleic acid metabolic process#GO:0090304;cell death#GO:0008219;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of signal transduction#GO:0009966;nucleobase-containing compound metabolic process#GO:0006139;response to radiation#GO:0009314;apoptotic signaling pathway#GO:0097190;regulation of TORC1 signaling#GO:1903432;regulation of telomere maintenance#GO:0032204;DNA repair#GO:0006281;regulation of chromosome organization#GO:0033044;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;negative regulation of biological process#GO:0048519;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of organelle organization#GO:0033043;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to abiotic stimulus#GO:0071214;DNA metabolic process#GO:0006259;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;positive regulation of DNA metabolic process#GO:0051054;cellular response to stimulus#GO:0051716;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>ATM#P04669;p53 pathway#P00059>ATM/ATR#P01481 GORGO|Ensembl=ENSGGOG00000028354.2|UniProtKB=G3RXN0 G3RXN0 PTHR12489:SF20 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 7 PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016830.3|UniProtKB=G3RKZ0 G3RKZ0 STK17B PTHR24342:SF5 SERINE/THREONINE-PROTEIN KINASE 17 SERINE_THREONINE-PROTEIN KINASE 17B protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000027698.2|UniProtKB=G3S3W0 G3S3W0 LOC101150651 PTHR21213:SF15 GEO09665P1-RELATED ZINC FINGER PROTEIN 706 GORGO|Ensembl=ENSGGOG00000026032.2|UniProtKB=G3RND2 G3RND2 GZMK PTHR24271:SF52 KALLIKREIN-RELATED GRANZYME K catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;signal transduction#GO:0007165;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cell communication#GO:0007154;protein metabolic process#GO:0019538;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell death#GO:0008219;primary metabolic process#GO:0044238;programmed cell death#GO:0012501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000012833.3|UniProtKB=G3RMQ6 G3RMQ6 RASSF4 PTHR22738:SF4 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 4 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003072.3|UniProtKB=G3SE45 G3SE45 HOATZ PTHR47231:SF1 UPF0722 PROTEIN C11ORF88 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN HOATZ GORGO|Ensembl=ENSGGOG00000008986.3|UniProtKB=A0A2I2ZXF4 A0A2I2ZXF4 CDC14B PTHR23339:SF74 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14B phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cellular component assembly#GO:0022607;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell projection assembly#GO:0030031;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;cilium assembly#GO:0060271;cellular component organization#GO:0016043;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of mitotic cell cycle phase transition#GO:1901990;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;organelle assembly#GO:0070925;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011709.3|UniProtKB=G3R7S6 G3R7S6 CD74 PTHR14093:SF17 HLA CLASS II GAMMA CHAIN HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN molecular transducer activity#GO:0060089;protein binding#GO:0005515;MHC protein binding#GO:0042287;signaling receptor binding#GO:0005102;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;cytokine receptor activity#GO:0004896 regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;leukocyte activation#GO:0045321;regulation of intrinsic apoptotic signaling pathway#GO:2001242;positive regulation of cytokine production#GO:0001819;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cell activation#GO:0001775;positive regulation of biosynthetic process#GO:0009891;regulation of response to cytokine stimulus#GO:0060759;lymphocyte activation involved in immune response#GO:0002285;regulation of multicellular organismal process#GO:0051239;T cell activation involved in immune response#GO:0002286;immune effector process#GO:0002252;regulation of apoptotic process#GO:0042981;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of MAPK cascade#GO:0043408;T cell activation#GO:0042110;regulation of programmed cell death#GO:0043067;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;cell activation involved in immune response#GO:0002263;regulation of cellular response to stress#GO:0080135;positive regulation of cytokine-mediated signaling pathway#GO:0001961;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of MAPK cascade#GO:0043410;regulation of biosynthetic process#GO:0009889;positive regulation of signal transduction#GO:0009967;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of apoptotic signaling pathway#GO:2001233;regulation of immune response#GO:0050776;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of ERK1 and ERK2 cascade#GO:0070372;lymphocyte activation#GO:0046649;negative regulation of signal transduction#GO:0009968;leukocyte activation involved in immune response#GO:0002366;regulation of cytokine-mediated signaling pathway#GO:0001959;negative regulation of biological process#GO:0048519;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;regulation of cytokine production involved in immune response#GO:0002718;regulation of signaling#GO:0023051;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell communication#GO:0010648 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 T cell activation#P00053>MHC-antigen#P01316 GORGO|Ensembl=ENSGGOG00000006821.3|UniProtKB=G3QVB1 G3QVB1 RAB25 PTHR47979:SF8 DRAB11-RELATED RAS-RELATED PROTEIN RAB-25 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;transport#GO:0006810 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000009977.3|UniProtKB=G3SIZ2 G3SIZ2 CXCL5 PTHR12015:SF197 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 5 signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell motility#GO:0048870;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;response to bacterium#GO:0009617;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cell migration#GO:0016477;response to other organism#GO:0051707;immune response#GO:0006955;cellular response to molecule of bacterial origin#GO:0071219;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;leukocyte migration#GO:0050900;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to molecule of bacterial origin#GO:0002237;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;defense response to other organism#GO:0098542;response to lipid#GO:0033993;granulocyte migration#GO:0097530;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;neutrophil migration#GO:1990266;taxis#GO:0042330;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;response to lipopolysaccharide#GO:0032496;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;neutrophil chemotaxis#GO:0030593 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000025383.2|UniProtKB=G3SJI6 G3SJI6 THAP7 PTHR47502:SF1 THAP DOMAIN-CONTAINING PROTEIN 7 THAP DOMAIN-CONTAINING PROTEIN 7 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000011201.3|UniProtKB=G3R6G9 G3R6G9 MOB3A PTHR22599:SF10 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3A protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000009256.3|UniProtKB=G3R1H5 G3R1H5 LOC101150353 PTHR24271:SF3 KALLIKREIN-RELATED KALLIKREIN-13 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000041370.1|UniProtKB=G3QDS5 G3QDS5 FDPS PTHR15591:SF16 RUN AND SH3 DOMAIN CONTAINING FARNESYL PYROPHOSPHATE SYNTHASE intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000036884.1|UniProtKB=A0A2I2YYD0 A0A2I2YYD0 GCA PTHR46735:SF5 CALPAIN, SMALL SUBUNIT 1 A-RELATED GRANCALCIN calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 GORGO|Ensembl=ENSGGOG00000012245.3|UniProtKB=G3R977 G3R977 ARNT2 PTHR23042:SF6 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000015729.3|UniProtKB=G3RI56 G3RI56 ALDH3B2 PTHR43570:SF6 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER B2 aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000002536.3|UniProtKB=G3QJA9 G3QJA9 CHMP7 PTHR22761:SF21 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 7 intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;nucleus organization#GO:0006997;endosomal transport#GO:0016197;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;membrane assembly#GO:0071709;late endosome to vacuole transport#GO:0045324 cell periphery#GO:0071944;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasmic side of membrane#GO:0098562;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;side of membrane#GO:0098552 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000008176.3|UniProtKB=G3QYQ1 G3QYQ1 PTHR24379:SF68 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 443 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000000181.3|UniProtKB=G3QD68 G3QD68 PTHR43884:SF47 ACYL-COA DEHYDROGENASE ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000004531.3|UniProtKB=G3QPF6 G3QPF6 CEMIP PTHR15535:SF15 TRANSMEMBRANE PROTEIN 2-RELATED CELL MIGRATION-INDUCING AND HYALURONAN-BINDING PROTEIN hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosaminoglycan catabolic process#GO:0006027;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000009397.3|UniProtKB=G3R1U6 G3R1U6 NFKBIA PTHR46680:SF1 NF-KAPPA-B INHIBITOR ALPHA NF-KAPPA-B INHIBITOR ALPHA binding#GO:0005488;transcription factor binding#GO:0008134;molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 regulation of cell communication#GO:0010646;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 T cell activation#P00053>I kappa B#P01323;B cell activation#P00010>I kappa B#P00392;Apoptosis signaling pathway#P00006>IkappaB#P00292;CCKR signaling map#P06959>IKBalpha#P07053;Toll receptor signaling pathway#P00054>IkappaB#P01338;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IkappaB#P00857 GORGO|Ensembl=ENSGGOG00000001126.3|UniProtKB=G3QFN3 G3QFN3 CEP78 PTHR24110:SF3 CENTROSOMAL PROTEIN OF 78 KDA CENTROSOMAL PROTEIN OF 78 KDA cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011565.3|UniProtKB=G3R7G1 G3R7G1 POLQ PTHR10133:SF64 DNA POLYMERASE I DNA POLYMERASE THETA DNA-directed DNA polymerase activity#GO:0003887;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 DNA-directed DNA polymerase#PC00018 GORGO|Ensembl=ENSGGOG00000027619.2|UniProtKB=A0A2I2YFH7 A0A2I2YFH7 LOC101140955 PTHR48034:SF18 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA-BINDING MOTIF PROTEIN, X CHROMOSOME mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000043216.1|UniProtKB=A0A2I2ZI42 A0A2I2ZI42 METTL8 PTHR22809:SF3 METHYLTRANSFERASE-RELATED TRNA N(3)-CYTIDINE METHYLTRANSFERASE METTL8, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000010076.3|UniProtKB=G3R3J8 G3R3J8 KCTD21 PTHR14499:SF57 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD21 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011543.3|UniProtKB=G3R7C7 G3R7C7 POLR3F PTHR12780:SF1 RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 GORGO|Gene=FPR3|UniProtKB=P79178 P79178 FPR3 PTHR24225:SF58 CHEMOTACTIC RECEPTOR SUBFAMILY NOT NAMED G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000026856.2|UniProtKB=G3S725 G3S725 PSMB5 PTHR11599:SF51 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-5 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000009568.3|UniProtKB=G3R2A1 G3R2A1 DCAKD PTHR10695:SF46 DEPHOSPHO-COA KINASE-RELATED DEPHOSPHO-COA KINASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886;Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884 GORGO|Ensembl=ENSGGOG00000010345.3|UniProtKB=G3R496 G3R496 CRYAA PTHR45640:SF14 HEAT SHOCK PROTEIN HSP-12.2-RELATED ALPHA-CRYSTALLIN A CHAIN macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;camera-type eye development#GO:0043010;regulation of cellular process#GO:0050794;visual system development#GO:0150063;primary metabolic process#GO:0044238;animal organ development#GO:0048513;multicellular organism development#GO:0007275;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;lens development in camera-type eye#GO:0002088;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;response to stress#GO:0006950;sensory system development#GO:0048880;response to heat#GO:0009408;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;protein refolding#GO:0042026;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;protein folding#GO:0006457;response to abiotic stimulus#GO:0009628;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 GORGO|Ensembl=ENSGGOG00000008568.3|UniProtKB=G3QZS3 G3QZS3 CEP120 PTHR21574:SF0 CENTROSOMAL PROTEIN OF 120 KDA CENTROSOMAL PROTEIN OF 120 KDA cellular process#GO:0009987;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005661.3|UniProtKB=G3QSB2 G3QSB2 MAIP1 PTHR13333:SF5 M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000042786.1|UniProtKB=A0A2I2ZHC9 A0A2I2ZHC9 MYCT1 PTHR14869:SF0 MYC TARGET PROTEIN 1 MYC TARGET PROTEIN 1 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005381.3|UniProtKB=G3RQF7 G3RQF7 LOC101150168 PTHR11588:SF133 TUBULIN TUBULIN ALPHA-1A CHAIN guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 mitotic cell cycle#GO:0000278;cell differentiation#GO:0030154;cell cycle#GO:0007049;cellular component organization#GO:0016043;system development#GO:0048731;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;organelle organization#GO:0006996;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 tubulin#PC00228;cytoskeletal protein#PC00085 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 GORGO|Ensembl=ENSGGOG00000026751.2|UniProtKB=G3S3W9 G3S3W9 LOC101153588 PTHR11071:SF433 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000004579.3|UniProtKB=G3QPJ2 G3QPJ2 ZNF560 PTHR23226:SF409 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 275 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006865.3|UniProtKB=G3QVF7 G3QVF7 HAL PTHR10362:SF85 HISTIDINE AMMONIA-LYASE HISTIDINE AMMONIA-LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 lyase#PC00144 GORGO|Ensembl=ENSGGOG00000015536.3|UniProtKB=G3RQW9 G3RQW9 MEGF6 PTHR24035:SF137 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 6 phagocytosis#GO:0006909;transport#GO:0006810;membrane invagination#GO:0010324;import into cell#GO:0098657;establishment of localization#GO:0051234;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;apoptotic cell clearance#GO:0043277;cellular component organization#GO:0016043;cellular process#GO:0009987;endocytosis#GO:0006897;membrane organization#GO:0061024 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000010227.2|UniProtKB=G3R3Y7 G3R3Y7 LOC101127646 PTHR23415:SF42 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 mitotic cell cycle process#GO:1903047;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle phase transition#GO:0044772;cell cycle#GO:0007049 cellular anatomical structure#GO:0110165;organelle#GO:0043226;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026320.2|UniProtKB=G3RZP2 G3RZP2 PTHR31353:SF11 FAM98 TRNA-SPLICING LIGASE COMPLEX SUBUNIT FAM98B intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000026332.2|UniProtKB=G3S7S5 G3S7S5 YY1 PTHR14003:SF10 TRANSCRIPTIONAL REPRESSOR PROTEIN YY TRANSCRIPTIONAL REPRESSOR PROTEIN YY1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;DNA damage response#GO:0006974;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;cellular response to stress#GO:0033554;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 chromosome#GO:0005694;PcG protein complex#GO:0031519;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002386.3|UniProtKB=G3RQH2 G3RQH2 PNLIPRP3 PTHR11610:SF100 LIPASE PANCREATIC LIPASE-RELATED PROTEIN 3 hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000036943.1|UniProtKB=G3S5C5 G3S5C5 LOC101130972 PTHR23262:SF7 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 2-2-RELATED structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000008327.4|UniProtKB=G3QZ38 G3QZ38 BIRC2 PTHR10044:SF79 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;transferase activity#GO:0016740;enzyme regulator activity#GO:0030234;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;positive regulation of protein metabolic process#GO:0051247;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;positive regulation of protein ubiquitination#GO:0031398;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of protein ubiquitination#GO:0031396;regulation of apoptotic process#GO:0042981;regulation of protein modification process#GO:0031399 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 Apoptosis signaling pathway#P00006>c-IAP1,2#P00264;CCKR signaling map#P06959>BIRC2#G07278 GORGO|Ensembl=ENSGGOG00000006677.3|UniProtKB=G3QUX3 G3QUX3 SLC45A3 PTHR19432:SF37 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000028549.2|UniProtKB=G3SFE5 G3SFE5 PTHR46374:SF2 PROTEIN CBG07384 STAR-RELATED LIPID TRANSFER PROTEIN 6 GORGO|Ensembl=ENSGGOG00000043160.1|UniProtKB=A0A2I2Z919 A0A2I2Z919 ZNF250 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011262.3|UniProtKB=G3R6L9 G3R6L9 FUCA2 PTHR10030:SF45 ALPHA-L-FUCOSIDASE PLASMA ALPHA-L-FUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;glycosyl compound catabolic process#GO:1901658;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 hydrolase#PC00121;glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000026960.2|UniProtKB=G3RWJ9 G3RWJ9 SQSTM1 PTHR15090:SF0 SEQUESTOSOME 1-RELATED SEQUESTOSOME-1 protein binding#GO:0005515;binding#GO:0005488;modification-dependent protein binding#GO:0140030;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;polyubiquitin modification-dependent protein binding#GO:0031593;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530 mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;process utilizing autophagic mechanism#GO:0061919;vesicle organization#GO:0016050;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;catabolic process#GO:0009056;endomembrane system organization#GO:0010256;macroautophagy#GO:0016236;organelle organization#GO:0006996;cellular component organization#GO:0016043;autophagy#GO:0006914;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000025640.2|UniProtKB=G3S1J0 G3S1J0 ATP7A PTHR43520:SF29 ATP7, ISOFORM B COPPER-TRANSPORTING ATPASE 1 copper ion binding#GO:0005507;transporter activity#GO:0005215;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;transition metal ion transmembrane transporter activity#GO:0046915;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;metal ion binding#GO:0046872;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ion binding#GO:0043167;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;cation binding#GO:0043169 cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;copper ion transmembrane transport#GO:0035434;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000024971.2|UniProtKB=A0A2I2YIH8 A0A2I2YIH8 LOC101139980 PTHR46139:SF1 ALKALINE CERAMIDASE ALKALINE CERAMIDASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 ceramide metabolic process#GO:0006672;sphingoid biosynthetic process#GO:0046520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid catabolic process#GO:0016042;alcohol biosynthetic process#GO:0046165 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Gene=PCSK9|UniProtKB=A8T650 A8T650 PCSK9 PTHR43806:SF60 PEPTIDASE S8 PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 9 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000010798.3|UniProtKB=G3R5G5 G3R5G5 CFAP65 PTHR46127:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65 microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017 motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000007683.3|UniProtKB=G3QXH1 G3QXH1 TRMO PTHR12818:SF0 TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175 GORGO|Ensembl=ENSGGOG00000022873.2|UniProtKB=G3SFZ4 G3SFZ4 KCNJ3 PTHR11767:SF16 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 1 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215 potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;GABA-B receptor II signaling#P05731>K channel#P05758;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083 GORGO|Ensembl=ENSGGOG00000007307.3|UniProtKB=G3QWJ5 G3QWJ5 PCSK4 PTHR42884:SF16 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 4 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;proteolysis#GO:0006508;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;hormone metabolic process#GO:0042445;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;protein processing#GO:0016485;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 GORGO|Ensembl=ENSGGOG00000005441.3|UniProtKB=G3QRR8 G3QRR8 SCN1A PTHR10037:SF280 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 1 SUBUNIT ALPHA passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;sensory perception of pain#GO:0019233;action potential#GO:0001508;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transmission of nerve impulse#GO:0019226;system process#GO:0003008;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;transporter complex#GO:1990351;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;axon#GO:0030424 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000009550.3|UniProtKB=G3R284 G3R284 TRIM60 PTHR24103:SF304 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 60 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;immune system process#GO:0002376;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005899.3|UniProtKB=G3QSY2 G3QSY2 ACTN4 PTHR11915:SF425 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-4 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856 cytoskeleton#GO:0005856;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 GORGO|Ensembl=ENSGGOG00000010590.3|UniProtKB=A0A2I2YQ85 A0A2I2YQ85 PTHR12806:SF2 EAP30 SUBUNIT OF ELL COMPLEX VACUOLAR-SORTING PROTEIN SNF8 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein transport#GO:0015031;cellular localization#GO:0051641;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;establishment of protein localization to vacuole#GO:0072666;intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509 membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000001866.3|UniProtKB=G3QHK8 G3QHK8 BMERB1 PTHR22704:SF1 BMERB DOMAIN-CONTAINING PROTEIN 1-RELATED BMERB DOMAIN-CONTAINING PROTEIN 1 regulation of microtubule-based process#GO:0032886;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein-containing complex disassembly#GO:0043244;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of microtubule cytoskeleton organization#GO:0070507 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000027474.2|UniProtKB=G3RS20 G3RS20 PTHR13456:SF0 UPF0729 PROTEIN C18ORF32 UPF0729 PROTEIN C18ORF32 GORGO|Ensembl=ENSGGOG00000007018.3|UniProtKB=G3QVU2 G3QVU2 RPAP1 PTHR21483:SF18 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 GORGO|Ensembl=ENSGGOG00000003661.3|UniProtKB=G3QM74 G3QM74 COL6A2 PTHR24023:SF936 COLLAGEN ALPHA COLLAGEN ALPHA-2(VI) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000041385.1|UniProtKB=A0A2I2Y674 A0A2I2Y674 PTHR13337:SF8 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT small molecule binding#GO:0036094;binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000022063.2|UniProtKB=A0A2I2ZIJ1 A0A2I2ZIJ1 PTHR24068:SF477 UBIQUITIN-CONJUGATING ENZYME E2 UBC CORE DOMAIN-CONTAINING PROTEIN ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;response to stress#GO:0006950;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000006597.3|UniProtKB=G3QUP9 G3QUP9 ZBTB22 PTHR46105:SF14 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 22 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001964.3|UniProtKB=A0A2I2ZR55 A0A2I2ZR55 MIX23 PTHR31905:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 PROTEIN MIX23 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000003060.3|UniProtKB=G3QKM9 G3QKM9 PTHR22017:SF0 PHOTORECEPTOR CILIUM ACTIN REGULATOR PHOTORECEPTOR CILIUM ACTIN REGULATOR multicellular organismal process#GO:0032501;nervous system development#GO:0007399;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;intracellular protein localization#GO:0008104;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;cell development#GO:0048468;cellular component organization#GO:0016043;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;photoreceptor inner segment#GO:0001917;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000028444.2|UniProtKB=G3S989 G3S989 PTHR48033:SF11 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A_B nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006082.3|UniProtKB=G3QTD8 G3QTD8 KCNK5 PTHR11003:SF241 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 5 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244 transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000001542.3|UniProtKB=G3QGR1 G3QGR1 DENND2D PTHR15288:SF2 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2D enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000014558.3|UniProtKB=G3S110 G3S110 ANKRD44 PTHR24161:SF130 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED TRANSIENT RECEPTOR POTENTIAL CHANNEL PYREXIA protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007271.3|UniProtKB=A0A2I2ZXC7 A0A2I2ZXC7 BTN3A1 PTHR24100:SF128 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 3 MEMBER A1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000006304.3|UniProtKB=G3QTY2 G3QTY2 DDC PTHR11999:SF167 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE AROMATIC-L-AMINO-ACID DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 serotonin biosynthetic process#GO:0042427;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;phenol-containing compound biosynthetic process#GO:0046189;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;catecholamine metabolic process#GO:0006584;serotonin metabolic process#GO:0042428;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;lyase#PC00144 Nicotine pharmacodynamics pathway#P06587>DDC#P06608;Dopamine receptor mediated signaling pathway#P05912>DOPA decarb.#P05961;Adrenaline and noradrenaline biosynthesis#P00001>DOPA decarb.#P00066;5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400 GORGO|Ensembl=ENSGGOG00000001176.3|UniProtKB=A0A2I2YRA5 A0A2I2YRA5 INTS6 PTHR12957:SF23 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;integrator complex#GO:0032039;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000012640.3|UniProtKB=G3RA74 G3RA74 ACAT1 PTHR18919:SF156 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;sterol metabolic process#GO:0016125;steroid metabolic process#GO:0008202 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 CCKR signaling map#P06959>ACAT1#G06992;CCKR signaling map#P06959>ACAT1#G07285 GORGO|Ensembl=ENSGGOG00000042568.1|UniProtKB=A0A2I2Y8V1 A0A2I2Y8V1 PTHR26452:SF771 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013676.4|UniProtKB=G3RCV6 G3RCV6 TYW3 PTHR23245:SF31 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3 HOMOLOG catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000022225.2|UniProtKB=G3SFZ6 G3SFZ6 PTHR15896:SF7 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED PROTEIN GOLM2 GORGO|Ensembl=ENSGGOG00000021929.2|UniProtKB=G3RYU4 G3RYU4 LGALS13 PTHR11346:SF120 GALECTIN GALACTOSIDE-BINDING SOLUBLE LECTIN 13-RELATED binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000002090.3|UniProtKB=G3SF67 G3SF67 TMPRSS4 PTHR24253:SF31 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 4 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular organelle#GO:0043229 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006258.3|UniProtKB=A0A2I2YJ02 A0A2I2YJ02 PTHR10732:SF10 40S RIBOSOMAL PROTEIN S17 SMALL RIBOSOMAL SUBUNIT PROTEIN ES17 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005354.3|UniProtKB=G3QRI8 G3QRI8 SMIM9 PTHR41687:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 9 SMALL INTEGRAL MEMBRANE PROTEIN 9 GORGO|Ensembl=ENSGGOG00000010728.3|UniProtKB=G3R589 G3R589 RHO PTHR24240:SF15 OPSIN RHODOPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 detection of stimulus#GO:0051606;cellular process#GO:0009987;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;biological regulation#GO:0065007;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;signaling#GO:0023052;cellular response to radiation#GO:0071478;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin#P00747 GORGO|Ensembl=ENSGGOG00000022196.2|UniProtKB=G3RU37 G3RU37 ZNF181 PTHR24381:SF457 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 181 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000010625.3|UniProtKB=G3R502 G3R502 BPIFB2 PTHR46019:SF1 BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED BPI FOLD-CONTAINING FAMILY B MEMBER 2 GORGO|Ensembl=ENSGGOG00000023406.2|UniProtKB=G3RZZ2 G3RZZ2 KLHL9 PTHR45632:SF31 LD33804P KELCH-LIKE PROTEIN 9 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;midbody#GO:0030496;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010886.3|UniProtKB=G3R5N1 G3R5N1 ACER1 PTHR46139:SF2 ALKALINE CERAMIDASE ALKALINE CERAMIDASE 1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid catabolic process#GO:0016042;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000014666.3|UniProtKB=G3RFG6 G3RFG6 DMXL2 PTHR13950:SF13 RABCONNECTIN-RELATED DMX-LIKE PROTEIN 2 cellular component assembly#GO:0022607;regulation of monoatomic ion transport#GO:0043269;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;regulation of monoatomic ion transmembrane transport#GO:0034765;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049;endosomal transport#GO:0016197;protein-containing complex organization#GO:0043933;regulation of monoatomic cation transmembrane transport#GO:1904062;intracellular transport#GO:0046907;transport#GO:0006810;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;regulation of transmembrane transport#GO:0034762;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;localization#GO:0051179;cellular localization#GO:0051641 secretory vesicle#GO:0099503;presynapse#GO:0098793;transport vesicle#GO:0030133;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000004564.3|UniProtKB=G3QPI0 G3QPI0 DBR1 PTHR12849:SF0 RNA LARIAT DEBRANCHING ENZYME LARIAT DEBRANCHING ENZYME RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000005461.3|UniProtKB=G3RT35 G3RT35 GNLY PTHR15541:SF2 GRANULYSIN RELATED GRANULYSIN defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;defense response to other organism#GO:0098542;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell killing#GO:0001906;response to external stimulus#GO:0009605;defense response#GO:0006952;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015171.3|UniProtKB=A0A2I2YGH9 A0A2I2YGH9 ITGA8 PTHR23220:SF5 INTEGRIN ALPHA INTEGRIN ALPHA-8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Collagen#P00922;Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000002431.3|UniProtKB=G3QJ13 G3QJ13 EGR3 PTHR23235:SF78 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022627.2|UniProtKB=A0A2I2YAM1 A0A2I2YAM1 PTHR10438:SF397 THIOREDOXIN THIOREDOXIN DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000023956.2|UniProtKB=G3S0N2 G3S0N2 LOC109027173 PTHR26453:SF746 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013947.3|UniProtKB=G3RTF0 G3RTF0 KCTD10 PTHR11145:SF14 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER BTB_POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 3 negative regulation of response to stimulus#GO:0048585;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of biological process#GO:0048519;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of Rho protein signal transduction#GO:0035023;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 Cul3-RING ubiquitin ligase complex#GO:0031463;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002319.3|UniProtKB=A0A2I2ZGV4 A0A2I2ZGV4 AGPAT1 PTHR10434:SF65 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE ALPHA acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;organophosphate biosynthetic process#GO:0090407 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000025523.2|UniProtKB=G3S0L0 G3S0L0 CXorf66 PTHR37340:SF1 GENE 7073-RELATED GENE 7073-RELATED GORGO|Ensembl=ENSGGOG00000013269.3|UniProtKB=A0A2I2YEN6 A0A2I2YEN6 PTHR12322:SF76 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;sex differentiation#GO:0007548;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000040732.1|UniProtKB=A0A2I2YUT1 A0A2I2YUT1 FAM163B PTHR31396:SF2 PROTEIN FAM163B MEMBER PROTEIN FAM163B GORGO|Ensembl=ENSGGOG00000006294.3|UniProtKB=A0A2I2YA43 A0A2I2YA43 VPS54 PTHR12965:SF0 VACUOLAR PROTEIN SORTING 54 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54 syntaxin binding#GO:0019905;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013058.3|UniProtKB=G3RB98 G3RB98 AVPR1B PTHR24241:SF18 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V1B RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of biological quality#GO:0065008;cell communication#GO:0007154;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003375.3|UniProtKB=G3QLH0 G3QLH0 EZH1 PTHR45747:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE EZH1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;binding#GO:0005488;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;chromatin binding#GO:0003682;N-methyltransferase activity#GO:0008170 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892 histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000039429.1|UniProtKB=A0A2I2YY99 A0A2I2YY99 PTHR48637:SF2 SECRETED PROTEIN-RELATED SECRETED PROTEIN GORGO|Ensembl=ENSGGOG00000025540.2|UniProtKB=A0A2I2ZJ21 A0A2I2ZJ21 RPS25 PTHR12850:SF18 40S RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN ES25 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000473.3|UniProtKB=G3QDY4 G3QDY4 ASB13 PTHR24136:SF53 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX CONTAINING 13 positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;positive regulation of protein metabolic process#GO:0051247;protein modification by small protein conjugation or removal#GO:0070647;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246 GORGO|Ensembl=ENSGGOG00000007664.3|UniProtKB=G3QXF5 G3QXF5 ALDH3A2 PTHR43570:SF9 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER A2 oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000017024.3|UniProtKB=G3RLG8 G3RLG8 SEPTIN1 PTHR18884:SF6 SEPTIN SEPTIN-1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 macromolecule localization#GO:0033036;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;intracellular protein localization#GO:0008104;cell cycle#GO:0007049;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cell division#GO:0051301;cell cycle process#GO:0022402;regulation of cellular process#GO:0050794;cytokinesis#GO:0000910;regulation of secretion#GO:0051046;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157 vesicle#GO:0031982;cell cortex#GO:0005938;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;presynapse#GO:0098793;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;secretory vesicle#GO:0099503;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 GORGO|Ensembl=ENSGGOG00000015004.3|UniProtKB=A0A2I2ZJL1 A0A2I2ZJL1 RMDN1 PTHR16056:SF16 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 1 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;spindle#GO:0005819;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;spindle pole#GO:0000922;mitochondrion#GO:0005739;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000001567.3|UniProtKB=G3QGT1 G3QGT1 ACOT4 PTHR10824:SF6 ACYL-COENZYME A THIOESTERASE-RELATED PEROXISOMAL SUCCINYL-COENZYME A THIOESTERASE hydrolase activity#GO:0016787;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;deacylase activity#GO:0160215;catalytic activity#GO:0003824;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000008630.3|UniProtKB=A0A2I2Z2M8 A0A2I2Z2M8 CLASP1 PTHR21567:SF28 CLASP CLIP-ASSOCIATING PROTEIN 1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;establishment of localization#GO:0051234;establishment of spindle localization#GO:0051293;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;spindle localization#GO:0051653;cellular localization#GO:0051641;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;establishment of organelle localization#GO:0051656;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;establishment of mitotic spindle localization#GO:0040001 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;cell periphery#GO:0071944;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;basal part of cell#GO:0045178;cytoplasmic microtubule#GO:0005881;chromosome#GO:0005694;kinetochore#GO:0000776;cell cortex#GO:0005938 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000008493.3|UniProtKB=G3QZI6 G3QZI6 GPR88 PTHR24240:SF234 OPSIN G PROTEIN-COUPLED RECEPTOR 88 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;response to radiation#GO:0009314;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000023146.2|UniProtKB=A0A2I2YQY3 A0A2I2YQY3 UBL3 PTHR13169:SF0 UBIQUITIN-LIKE PROTEIN 3 HCG-1 PROTEIN UBIQUITIN-LIKE PROTEIN 3 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009096.3|UniProtKB=G3R145 G3R145 CS PTHR11739:SF8 CITRATE SYNTHASE CITRATE SYNTHASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 transferase#PC00220;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Citrate Synthetase#P03141;TCA cycle#P00051>Citrate Synthase#P01267 GORGO|Ensembl=ENSGGOG00000001538.3|UniProtKB=G3QGQ7 G3QGQ7 TACR1 PTHR46925:SF4 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED SUBSTANCE-P RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of reproductive process#GO:2000241;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of microtubule-based process#GO:0032886;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729 G-protein coupled receptor#PC00021 CCKR signaling map#P06959>TACR1#G07279;CCKR signaling map#P06959>TACR1#G06985 GORGO|Ensembl=ENSGGOG00000041711.1|UniProtKB=A0A2I2ZQH1 A0A2I2ZQH1 SHC2 PTHR10337:SF5 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Shc#P00554;Angiogenesis#P00005>Sck#P00202;PDGF signaling pathway#P00047>Shc#P01175;VEGF signaling pathway#P00056>Sck#P01424 GORGO|Ensembl=ENSGGOG00000011539.3|UniProtKB=G3R7B8 G3R7B8 PARM1 PTHR35453:SF1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;plasma membrane#GO:0005886;late endosome#GO:0005770;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 GORGO|Ensembl=ENSGGOG00000005225.3|UniProtKB=G3SH79 G3SH79 PTHR12406:SF22 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE PNPLA3 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;triacylglycerol lipase activity#GO:0004806;carboxylic ester hydrolase activity#GO:0052689 lipid catabolic process#GO:0016042;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;neutral lipid catabolic process#GO:0046461;glycerophospholipid biosynthetic process#GO:0046474;triglyceride metabolic process#GO:0006641;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;phosphorus metabolic process#GO:0006793;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;triglyceride catabolic process#GO:0019433;glycerolipid catabolic process#GO:0046503;organophosphate biosynthetic process#GO:0090407 intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000036163.1|UniProtKB=A0A2I2Z0A4 A0A2I2Z0A4 PTHR21637:SF6 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED BTBD10_KCTD20 BTB_POZ DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000004322.3|UniProtKB=A0A2I2ZEU4 A0A2I2ZEU4 ZNF446 PTHR23226:SF210 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 446 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011978.3|UniProtKB=A0A2I2Y9F4 A0A2I2Y9F4 SNX8 PTHR46571:SF1 SORTING NEXIN-8 SORTING NEXIN-8 protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;cytosolic transport#GO:0016482;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001714.3|UniProtKB=A0A2I2ZA49 A0A2I2ZA49 SMC1B PTHR18937:SF147 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1B DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;nucleus#GO:0005634;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000027475.2|UniProtKB=G3RRI7 G3RRI7 PTHR31943:SF1 INTERLEUKIN-28 AND 29 INTERFERON LAMBDA-2-RELATED cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 response to virus#GO:0009615;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;defense response to virus#GO:0051607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000009468.3|UniProtKB=G3R214 G3R214 SLC16A2 PTHR11360:SF123 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 8 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monocarboxylic acid transmembrane transporter activity#GO:0008028;active transmembrane transporter activity#GO:0022804 regulation of hormone levels#GO:0010817;hormone transport#GO:0009914;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011771.3|UniProtKB=A0A2I2ZPX0 A0A2I2ZPX0 MAPK8 PTHR24055:SF222 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 8 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 response to mechanical stimulus#GO:0009612;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;JNK cascade#GO:0007254;regulation of apoptotic process#GO:0042981;response to external stimulus#GO:0009605;positive regulation of apoptotic process#GO:0043065;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Angiogenesis#P00005>JNK1#P00221;Ras Pathway#P04393>JNK#P04572;PDGF signaling pathway#P00047>ERK#P01143;B cell activation#P00010>Jnk#P00402;CCKR signaling map#P06959>MAPK8-10#P07090;Apoptosis signaling pathway#P00006>JNK#P00274;Gonadotropin-releasing hormone receptor pathway#P06664>JNK1/2#P06847;Oxidative stress response#P00046>JNK1/2#P01129;Parkinson disease#P00049>SAPK#P01219;Toll receptor signaling pathway#P00054>JNK#P01375;TGF-beta signaling pathway#P00052>JNK#P01284;T cell activation#P00053>Jnk#P01336;FGF signaling pathway#P00021>JNK1-3#P00628;Integrin signalling pathway#P00034>Jnk#P00951;FAS signaling pathway#P00020>JNK#P00615;EGF receptor signaling pathway#P00018>JNK1-3#P00545 GORGO|Gene=B3GALT5|UniProtKB=Q9N293 Q9N293 B3GALT5 PTHR11214:SF265 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 5 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000041546.1|UniProtKB=A0A2I2YQC9 A0A2I2YQC9 PTHR46708:SF3 TENASCIN TENASCIN-X extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000009234.3|UniProtKB=G3RQJ7 G3RQJ7 CEACAM19 PTHR44427:SF21 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CEA CELL ADHESION MOLECULE 19 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000006340.3|UniProtKB=G3QU05 G3QU05 P2RY8 PTHR24232:SF25 G-PROTEIN COUPLED RECEPTOR S-GERANYLGERANYL-GLUTATHIONE RECEPTOR P2RY8 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016875.3|UniProtKB=G3RL45 G3RL45 STXBP5 PTHR10241:SF22 LETHAL 2 GIANT LARVAE PROTEIN SYNTAXIN-BINDING PROTEIN 5 GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;SNARE binding#GO:0000149;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;syntaxin binding#GO:0019905;molecular function activator activity#GO:0140677;binding#GO:0005488 export from cell#GO:0140352;Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;exocytosis#GO:0006887;post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940;vesicle-mediated transport to the plasma membrane#GO:0098876;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;secretion#GO:0046903;localization within membrane#GO:0051668;Golgi vesicle transport#GO:0048193;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000015826.3|UniProtKB=G3RID6 G3RID6 ABHD6 PTHR43798:SF5 MONOACYLGLYCEROL LIPASE MONOACYLGLYCEROL LIPASE ABHD6 protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235 lipase#PC00143;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000025903.2|UniProtKB=A0A2I2YUP9 A0A2I2YUP9 PTHR11937:SF547 ACTIN POTE ANKYRIN DOMAIN FAMILY MEMBER E-RELATED structural constituent of synapse#GO:0098918;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell motility#GO:0048870;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 membrane#GO:0016020;H4 histone acetyltransferase complex#GO:1902562;cytoskeleton#GO:0005856;transferase complex#GO:1990234;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin filament#GO:0005884;cell junction#GO:0030054;histone acetyltransferase complex#GO:0000123;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;supramolecular fiber#GO:0099512 actin and actin related protein#PC00039 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Cadherin signaling pathway#P00012>F-actin#P00470;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944 GORGO|Ensembl=ENSGGOG00000042959.1|UniProtKB=A0A2I2ZUV5 A0A2I2ZUV5 PTHR11879:SF47 ASPARTATE AMINOTRANSFERASE ASPARTATE TRANSAMINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000026749.2|UniProtKB=G3RVX7 G3RVX7 PIP4K2C PTHR23086:SF35 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 GAMMA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transferase#PC00220;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000014627.2|UniProtKB=G3RFA3 G3RFA3 PTHR10732:SF14 40S RIBOSOMAL PROTEIN S17 SMALL RIBOSOMAL SUBUNIT PROTEIN ES17 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011093.3|UniProtKB=G3R675 G3R675 PSD3 PTHR10663:SF337 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 3 cell projection membrane#GO:0031253;ruffle#GO:0001726;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000025563.2|UniProtKB=G3S0P0 G3S0P0 DCAF17 PTHR14815:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 17 DDB1- AND CUL4-ASSOCIATED FACTOR 17 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 GORGO|Ensembl=ENSGGOG00000014113.3|UniProtKB=G3S692 G3S692 LRRC20 PTHR16083:SF87 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 20 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008882.3|UniProtKB=G3S4M6 G3S4M6 ZNF462 PTHR24403:SF58 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 462 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000042769.1|UniProtKB=A0A2I2ZHI1 A0A2I2ZHI1 LOC101145974 PTHR11468:SF3 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, LIVER FORM hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular process#GO:0009987;glycogen catabolic process#GO:0005980;carbohydrate catabolic process#GO:0016052;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 GORGO|Ensembl=ENSGGOG00000008898.3|UniProtKB=A0A2I2ZQT4 A0A2I2ZQT4 PHYHIPL PTHR15698:SF8 PROTEIN CBG15099 PHYTANOYL-COA HYDROXYLASE-INTERACTING PROTEIN-LIKE cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000011979.3|UniProtKB=G3R8H3 G3R8H3 ACY3 PTHR15162:SF5 ASPARTOACYLASE N-ACYL-AROMATIC-L-AMINO ACID AMIDOHYDROLASE (CARBOXYLATE-FORMING) catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000002864.3|UniProtKB=G3QK48 G3QK48 FAM210A PTHR21377:SF1 PROTEIN FAM210B, MITOCHONDRIAL MITOCHONDRIAL INNER MEMBRANE SCAFFOLD 1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000040730.1|UniProtKB=A0A2I2YWV2 A0A2I2YWV2 TFG PTHR15335:SF7 PROTEIN TFG PROTEIN TFG intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012843.3|UniProtKB=G3RAQ0 G3RAQ0 PTHR24072:SF153 RHO FAMILY GTPASE TRANSFORMING PROTEIN RHOA catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515 actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;cell migration#GO:0016477;contractile actin filament bundle assembly#GO:0030038;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;actin filament bundle assembly#GO:0051017;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;intracellular signaling cassette#GO:0141124;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;Rho protein signal transduction#GO:0007266;stress fiber assembly#GO:0043149;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;actomyosin structure organization#GO:0031032;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;actin filament bundle organization#GO:0061572;regulation of biological process#GO:0050789 cell junction#GO:0030054;cleavage furrow#GO:0032154;somatodendritic compartment#GO:0036477;cell division site#GO:0032153;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;neuron projection#GO:0043005;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic spine#GO:0043197;postsynapse#GO:0098794 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rho#P00948;Ras Pathway#P04393>Rho#P04578;CCKR signaling map#P06959>RHOA-GDP#P07019;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Axon guidance mediated by semaphorins#P00007>Rho#P00341;CCKR signaling map#P06959>RHOA-GTP#P07188;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Angiogenesis#P00005>GTPase#P00254 GORGO|Ensembl=ENSGGOG00000036305.1|UniProtKB=A0A2I2ZE28 A0A2I2ZE28 SFXN4 PTHR11153:SF3 SIDEROFLEXIN SIDEROFLEXIN-4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 mitochondrial transport#GO:0006839;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;intracellular transport#GO:0046907;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810 mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000012707.3|UniProtKB=G3RUL0 G3RUL0 PTHR24025:SF10 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-4 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000009347.3|UniProtKB=G3R1P6 G3R1P6 RAET1E PTHR16675:SF64 MHC CLASS I-RELATED RETINOIC ACID EARLY TRANSCRIPT 1E protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;cell killing#GO:0001906;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of leukocyte mediated immunity#GO:0002703;natural killer cell mediated cytotoxicity#GO:0042267;immune effector process#GO:0002252;defense response to other organism#GO:0098542;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cell killing#GO:0031341;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;biological process involved in interspecies interaction between organisms#GO:0044419;leukocyte mediated cytotoxicity#GO:0001909;regulation of biological process#GO:0050789;natural killer cell mediated immunity#GO:0002228 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000011930.3|UniProtKB=G3R8E0 G3R8E0 PTHR13667:SF5 HOMOLOC-13 WD REPEAT-CONTAINING AND PLANAR CELL POLARITY EFFECTOR PROTEIN FRITZ HOMOLOG GORGO|Ensembl=ENSGGOG00000023920.2|UniProtKB=A0A2I2Z7C5 A0A2I2Z7C5 GPRC5B PTHR14511:SF9 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G PROTEIN-COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER B kinase activator activity#GO:0019209;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 extracellular region#GO:0005576;signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000037548.1|UniProtKB=A0A2I2Z3Z0 A0A2I2Z3Z0 C16H15orf62 PTHR15344:SF8 CDC42 EFFECTOR PROTEIN BORG SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 62 binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;protein binding#GO:0005515 positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;response to stimulus#GO:0050896;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;positive regulation of organelle organization#GO:0010638;Rho protein signal transduction#GO:0007266;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;small GTPase-mediated signal transduction#GO:0007264;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of developmental process#GO:0050793;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cell projection assembly#GO:0060491;positive regulation of cell projection organization#GO:0031346 cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025262.2|UniProtKB=G3RMQ4 G3RMQ4 GEMIN8 PTHR16238:SF7 GEM-ASSOCIATED PROTEIN 8 GEM-ASSOCIATED PROTEIN 8 protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;spliceosomal snRNP assembly#GO:0000387;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085 protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;cellular anatomical structure#GO:0110165;SMN complex#GO:0032797;cytoplasm#GO:0005737;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000025627.2|UniProtKB=G3S0Y2 G3S0Y2 C11H2orf88 PTHR36471:SF1 SMALL MEMBRANE A-KINASE ANCHOR PROTEIN A-KINASE ANCHORING PROTEIN 19 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000897.3|UniProtKB=A0A2I2Z1R4 A0A2I2Z1R4 WDR91 PTHR13083:SF3 WD REPEAT-CONTAINING PROTEIN 91 WD REPEAT-CONTAINING PROTEIN 91 enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197 late endosome membrane#GO:0031902;early endosome membrane#GO:0031901;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000040816.1|UniProtKB=A0A2I2YR50 A0A2I2YR50 IDO2 PTHR28657:SF4 INDOLEAMINE 2,3-DIOXYGENASE INDOLEAMINE 2,3-DIOXYGENASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;carboxylic acid catabolic process#GO:0046395;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;indole-containing compound metabolic process#GO:0042430;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000015944.3|UniProtKB=G3RIQ3 G3RIQ3 CARMIL3 PTHR24112:SF43 LEUCINE-RICH REPEAT, ISOFORM F-RELATED CAPPING PROTEIN, ARP2_3 AND MYOSIN-I LINKER PROTEIN 3 regulation of organelle organization#GO:0033043;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000009281.3|UniProtKB=G3S9Y3 G3S9Y3 FMO5 PTHR23023:SF78 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE 5 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000043790.1|UniProtKB=A0A2I2YYI0 A0A2I2YYI0 ZNF420 PTHR23226:SF412 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013298.3|UniProtKB=G3S0W9 G3S0W9 DMRT1 PTHR12322:SF70 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;sex differentiation#GO:0007548;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000014719.3|UniProtKB=G3RFJ9 G3RFJ9 DDR1 PTHR24416:SF333 TYROSINE-PROTEIN KINASE RECEPTOR EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;collagen binding#GO:0005518;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013066.3|UniProtKB=G3RBA3 G3RBA3 C13H9orf152 PTHR36290:SF1 RIKEN CDNA D630039A03 GENE RIKEN CDNA D630039A03 GENE GORGO|Ensembl=ENSGGOG00000008613.3|UniProtKB=G3QZV0 G3QZV0 NDNF PTHR14619:SF1 NEURON-DERIVED NEUROTROPHIC FACTOR PROTEIN NDNF binding#GO:0005488;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;heparin binding#GO:0008201 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 GORGO|Ensembl=ENSGGOG00000022934.2|UniProtKB=A0A2I2ZPX9 A0A2I2ZPX9 LOC101141604 PTHR15606:SF5 DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED J DOMAIN-CONTAINING PROTEIN intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000016770.3|UniProtKB=G3RKS8 G3RKS8 LY6D PTHR16982:SF2 LYMPHOCYTE ANTIGEN 6D LYMPHOCYTE ANTIGEN 6D GORGO|Ensembl=ENSGGOG00000004943.3|UniProtKB=A0A2I2YEV2 A0A2I2YEV2 IGF1 PTHR46845:SF1 INSULIN-LIKE GROWTH FACTOR I INSULIN-LIKE GROWTH FACTOR 1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 signaling#GO:0023052;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;positive regulation of cell population proliferation#GO:0008284;negative regulation of biological process#GO:0048519;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell population proliferation#GO:0008283;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 Gonadotropin-releasing hormone receptor pathway#P06664>IGF-1#P06854;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896 GORGO|Ensembl=ENSGGOG00000003338.3|UniProtKB=A0A2I2ZXS4 A0A2I2ZXS4 AICDA PTHR13857:SF10 MRNA EDITING ENZYME SINGLE-STRANDED DNA CYTOSINE DEAMINASE hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 response to other organism#GO:0051707;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cytidine to uridine editing#GO:0016554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;response to virus#GO:0009615;macromolecule modification#GO:0043412;cellular process#GO:0009987;response to stress#GO:0006950;negative regulation of macromolecule biosynthetic process#GO:0010558;response to biotic stimulus#GO:0009607;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;base conversion or substitution editing#GO:0016553;RNA metabolic process#GO:0016070;RNA modification#GO:0009451 nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;P-body#GO:0000932;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000025133.2|UniProtKB=G3RZ42 G3RZ42 PPBP PTHR12015:SF216 SMALL INDUCIBLE CYTOKINE A PLATELET BASIC PROTEIN cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to molecule of bacterial origin#GO:0002237;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;neutrophil chemotaxis#GO:0030593;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to lipopolysaccharide#GO:0032496;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;taxis#GO:0042330;neutrophil migration#GO:1990266;response to chemical#GO:0042221;response to lipid#GO:0033993;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;cellular response to lipid#GO:0071396;chemotaxis#GO:0006935;inflammatory response#GO:0006954;response to bacterium#GO:0009617;cell chemotaxis#GO:0060326;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cell motility#GO:0048870;leukocyte migration#GO:0050900;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;cellular response to molecule of bacterial origin#GO:0071219;immune response#GO:0006955;response to other organism#GO:0051707;cell migration#GO:0016477 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000037713.1|UniProtKB=A0A2I2ZMC7 A0A2I2ZMC7 VTI1A PTHR21230:SF102 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A protein binding#GO:0005515;SNAP receptor activity#GO:0005484;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 cellular component organization#GO:0016043;cytosolic transport#GO:0016482;post-Golgi vesicle-mediated transport#GO:0006892;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152;endosomal transport#GO:0016197;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle fusion#GO:0006906;catabolic process#GO:0009056;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;membrane fusion#GO:0061025;retrograde transport, endosome to Golgi#GO:0042147;membrane organization#GO:0061024;macroautophagy#GO:0016236;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization#GO:0051234 membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;transport vesicle#GO:0030133;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 SNARE protein#PC00034;membrane traffic protein#PC00150 Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042 GORGO|Ensembl=ENSGGOG00000003599.3|UniProtKB=G3S4V0 G3S4V0 PHC2 PTHR12247:SF86 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 2 histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;protein binding#GO:0005515 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605 PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000039931.1|UniProtKB=A0A2I2ZCL9 A0A2I2ZCL9 PTHR12377:SF5 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED MIP18 FAMILY-LIKE DOMAIN-CONTAINING PROTEIN protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011289.3|UniProtKB=G3R6P0 G3R6P0 SDHAF1 PTHR47046:SF1 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitochondrial respiratory chain complex II assembly#GO:0034553;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000027746.2|UniProtKB=G3S064 G3S064 SP5 PTHR23235:SF29 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP5 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000042490.1|UniProtKB=A0A2I2YNQ0 A0A2I2YNQ0 PTHR22607:SF2 DELETED IN ORAL CANCER 1/CDK2-ASSOCIATED PROTEIN 1 CYCLIN-DEPENDENT KINASE 2-ASSOCIATED PROTEIN 1 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase modulator#PC00140;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000006694.3|UniProtKB=G3QUY7 G3QUY7 LOC101149676 PTHR10570:SF9 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular developmental process#GO:0048869;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;hemopoiesis#GO:0030097;biological regulation#GO:0065007;T cell differentiation#GO:0030217;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;cell communication#GO:0007154;immune system process#GO:0002376;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;leukocyte activation#GO:0045321;mononuclear cell differentiation#GO:1903131;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD3 eta#P01302 GORGO|Ensembl=ENSGGOG00000014531.3|UniProtKB=G3RF24 G3RF24 GLP1R PTHR45620:SF25 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON-LIKE PEPTIDE 1 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 regulation of blood pressure#GO:0008217;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of blood pressure#GO:0045777;response to stimulus#GO:0050896;signaling#GO:0023052;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009047.3|UniProtKB=G3R107 G3R107 PTPRH PTHR19134:SF297 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE H protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007311.3|UniProtKB=G3QWK5 G3QWK5 LVRN PTHR11533:SF31 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE Q exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000012431.3|UniProtKB=A0A2I2ZN11 A0A2I2ZN11 PTHR23068:SF13 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3-LIKE enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA methyltransferase#PC00013 GORGO|Ensembl=ENSGGOG00000013896.3|UniProtKB=G3RDG4 G3RDG4 ARID2 PTHR22970:SF14 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949 GORGO|Ensembl=ENSGGOG00000022478.2|UniProtKB=G3S0Z6 G3S0Z6 LOC101137471 PTHR11594:SF1 40S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN ES27 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014010.3|UniProtKB=G3RDQ4 G3RDQ4 CHST13 PTHR12137:SF60 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 13 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000012741.3|UniProtKB=A0A2I2Y6T5 A0A2I2Y6T5 NPHS1 PTHR11640:SF136 NEPHRIN NEPHRIN protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000013621.3|UniProtKB=G3RCP7 G3RCP7 CFAP107 PTHR31180:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107 intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;microtubule#GO:0005874;cytoplasmic microtubule#GO:0005881;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080 GORGO|Ensembl=ENSGGOG00000012845.3|UniProtKB=G3RAQ1 G3RAQ1 PPY PTHR10533:SF2 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PANCREATIC POLYPEPTIDE PROHORMONE hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;neuropeptide hormone activity#GO:0005184;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;feeding behavior#GO:0007631;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000009356.3|UniProtKB=G3R1R2 G3R1R2 MRPL12 PTHR45987:SF29 39S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013570.3|UniProtKB=G3S769 G3S769 MTA2 PTHR10865:SF4 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA2 binding#GO:0005488;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;protein binding#GO:0005515;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;histone deacetylase binding#GO:0042826;transcription coactivator activity#GO:0003713 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 p53 pathway#P00059>MTA2#P04615 GORGO|Ensembl=ENSGGOG00000012014.3|UniProtKB=A0A2I2Z6X3 A0A2I2Z6X3 MMD PTHR20855:SF26 ADIPOR/PROGESTIN RECEPTOR-RELATED MONOCYTE TO MACROPHAGE DIFFERENTIATION FACTOR G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006529.3|UniProtKB=G3QUI6 G3QUI6 ZNF224 PTHR24409:SF331 ZINC FINGER PROTEIN 142 C2H2-TYPE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000039001.1|UniProtKB=A0A2I2YBB3 A0A2I2YBB3 ZNF20 PTHR24377:SF837 IP01015P-RELATED ZINC FINGER PROTEIN 20 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004648.3|UniProtKB=G3SCY9 G3SCY9 CORO7 PTHR10856:SF20 CORONIN CORONIN-7 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;actin filament-based process#GO:0030029;positive regulation of signaling#GO:0023056;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015 actin filament#GO:0005884;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000007846.3|UniProtKB=A0A2I2ZCE6 A0A2I2ZCE6 LOC101132551 PTHR26453:SF295 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5V1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003209.3|UniProtKB=G3QL12 G3QL12 PIGO PTHR23071:SF1 PHOSPHATIDYLINOSITOL GLYCAN GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3, CATALYTIC SUBUNIT phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 GORGO|Ensembl=ENSGGOG00000027084.3|UniProtKB=G3SEW5 G3SEW5 CHIC2 PTHR13005:SF3 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 2 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi-associated vesicle#GO:0005798 GORGO|Ensembl=ENSGGOG00000023621.2|UniProtKB=A0A2I2ZUS5 A0A2I2ZUS5 LOC101129632 PTHR26452:SF38 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5K2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010739.3|UniProtKB=G3R5A0 G3R5A0 LOC101144032 PTHR10510:SF2 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A2-LIKE, MITOCHONDRIAL molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000008251.3|UniProtKB=G3QYX2 G3QYX2 PTHR11559:SF440 CARBOXYLESTERASE COCAINE ESTERASE hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000000085.3|UniProtKB=G3QCY1 G3QCY1 F11R PTHR45113:SF1 JUNCTIONAL ADHESION MOLECULE A JUNCTIONAL ADHESION MOLECULE A anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;cell development#GO:0048468;cellular developmental process#GO:0048869;system process#GO:0003008;developmental process#GO:0032502;endothelial cell differentiation#GO:0045446;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;digestion#GO:0007586;regulation of membrane permeability#GO:0090559;biological regulation#GO:0065007;cellular process#GO:0009987 cell-cell junction#GO:0005911;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell junction#GO:0030054 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000004105.3|UniProtKB=G3QNB7 G3QNB7 WDR38 PTHR22847:SF626 WD40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 38 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000011923.4|UniProtKB=A0A2I2ZJH8 A0A2I2ZJH8 LRP12 PTHR24270:SF47 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 12 cellular developmental process#GO:0048869;neuron migration#GO:0001764;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell migration#GO:0016477;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell motility#GO:0048870;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000010911.3|UniProtKB=A0A2I2ZI12 A0A2I2ZI12 MCM6 PTHR11630:SF73 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM6 nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;MCM complex#GO:0042555 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000005746.3|UniProtKB=A0A2I2ZBN6 A0A2I2ZBN6 ITIH4 PTHR10338:SF119 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H4 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000027631.2|UniProtKB=G3S7H0 G3S7H0 APPL1 PTHR12552:SF13 OLIGOPHRENIN 1 DCC-INTERACTING PROTEIN 13-ALPHA enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000014706.3|UniProtKB=A0A2I2Z3A3 A0A2I2Z3A3 GDF11 PTHR11848:SF166 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 11 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 response to transforming growth factor beta#GO:0071559;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000038664.1|UniProtKB=A0A2I2Z910 A0A2I2Z910 PTHR11817:SF101 PYRUVATE KINASE PYRUVATE KINASE PKM transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;pyruvate kinase activity#GO:0004743;phosphotransferase activity, alcohol group as acceptor#GO:0016773 purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;response to chemical#GO:0042221;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;response to hormone#GO:0009725;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;ribonucleoside diphosphate metabolic process#GO:0009185;response to endogenous stimulus#GO:0009719;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;cellular response to nitrogen compound#GO:1901699;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;response to nitrogen compound#GO:1901698;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;carbohydrate metabolic process#GO:0005975;cellular response to peptide hormone stimulus#GO:0071375;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;ADP catabolic process#GO:0046032;cellular response to oxygen-containing compound#GO:1901701;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;cellular response to chemical stimulus#GO:0070887;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;pyruvate metabolic process#GO:0006090;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;cellular response to insulin stimulus#GO:0032869;response to peptide hormone#GO:0043434;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 Glycolysis#P00024>Pyruvate kinase#P00675;Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 GORGO|Ensembl=ENSGGOG00000005980.3|UniProtKB=Q5NKV9 Q5NKV9 ICAM1 PTHR13771:SF18 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cellular process#GO:0009987;cell adhesion mediated by integrin#GO:0033627;cell adhesion#GO:0007155;leukocyte cell-cell adhesion#GO:0007159;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000000664.3|UniProtKB=G3QEG0 G3QEG0 ZPR1 PTHR10876:SF3 ZINC FINGER PROTEIN ZPR1 ZINC FINGER PROTEIN ZPR1 protein binding#GO:0005515;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000015321.3|UniProtKB=G3RH33 G3RH33 LOC101138079 PTHR21281:SF1 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 cellular process#GO:0009987;cilium movement#GO:0003341;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 GORGO|Ensembl=ENSGGOG00000003694.3|UniProtKB=G3QM98 G3QM98 SLC7A7 PTHR11785:SF303 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010548.3|UniProtKB=G3R4S4 G3R4S4 SYDE1 PTHR46150:SF2 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN SYDE1 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of Ras protein signal transduction#GO:0046578;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of biological process#GO:0050789 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000026836.2|UniProtKB=G3S0B6 G3S0B6 SAMD9 PTHR16155:SF17 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013987.3|UniProtKB=G3RT23 G3RT23 TIRAP PTHR22662:SF0 TIRAP TOLL_INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN Toll receptor signaling pathway#P00054>TIRAP#P01350 GORGO|Ensembl=ENSGGOG00000001903.3|UniProtKB=G3QHP1 G3QHP1 RTBDN PTHR10517:SF19 FOLATE RECEPTOR RETBINDIN molecular transducer activity#GO:0060089;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;signaling receptor activity#GO:0038023;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;vitamin transport#GO:0051180;localization#GO:0051179;nitrogen compound transport#GO:0071705;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000027687.2|UniProtKB=G3RSK4 G3RSK4 MGAT4D PTHR12062:SF10 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN MGAT4D transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;Golgi stack#GO:0005795;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000038424.1|UniProtKB=A0A2I2ZXS2 A0A2I2ZXS2 GTPBP1 PTHR43721:SF9 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 1 translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000040728.1|UniProtKB=A0A2I2ZLI9 A0A2I2ZLI9 PTHR23267:SF225 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 10-54 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014798.3|UniProtKB=G3RFR5 G3RFR5 SLC20A2 PTHR11101:SF83 PHOSPHATE TRANSPORTER SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;phosphate transmembrane transporter activity#GO:0005315;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 inorganic anion transport#GO:0015698;phosphate ion transport#GO:0006817;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040394.1|UniProtKB=A0A2I2Z2Y7 A0A2I2Z2Y7 PTHR24381:SF381 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 41 HOMOLOG sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000004971.3|UniProtKB=A0A2I2Z7U0 A0A2I2Z7U0 ITGAV PTHR23220:SF4 INTEGRIN ALPHA INTEGRIN ALPHA-V signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;integrin-mediated signaling pathway#GO:0007229;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731 integrin complex#GO:0008305;signaling receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636 cell adhesion molecule#PC00069;integrin#PC00126 CCKR signaling map#P06959>ITGAV#G07293;CCKR signaling map#P06959>ITGAV#G06999;CCKR signaling map#P06959>ITGAV#P07133;Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000005917.3|UniProtKB=A0A2I2Z2D9 A0A2I2Z2D9 SPATS2L PTHR15623:SF8 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2-RELATED SPATS2-LIKE PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000000643.3|UniProtKB=G3QEE0 G3QEE0 PNMA5 PTHR23095:SF4 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 5 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000001655.3|UniProtKB=G3QH13 G3QH13 GPR149 PTHR24229:SF32 NEUROPEPTIDES RECEPTOR G PROTEIN-COUPLED RECEPTOR 149-RELATED peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000012566.3|UniProtKB=G3RA09 G3RA09 RNF166 PTHR46016:SF4 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF166 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 GORGO|Ensembl=ENSGGOG00000017174.3|UniProtKB=G3RPX7 G3RPX7 RHD PTHR11730:SF43 AMMONIUM TRANSPORTER BLOOD GROUP RH(D) POLYPEPTIDE passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267 chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000022241.2|UniProtKB=G3RSB7 G3RSB7 PARP2 PTHR10459:SF118 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 2 catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 GORGO|Ensembl=ENSGGOG00000004217.3|UniProtKB=G3QNL7 G3QNL7 CASS4 PTHR10654:SF19 CAS SCAFFOLDING PROTEIN CAS SCAFFOLDING PROTEIN FAMILY MEMBER 4 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000025018.2|UniProtKB=G3RZF7 G3RZF7 PTHR24392:SF54 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 407 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011764.3|UniProtKB=G3R7Y1 G3R7Y1 MXD3 PTHR11969:SF6 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000042295.1|UniProtKB=A0A2I2Z245 A0A2I2Z245 RTRAF PTHR15924:SF11 CLE TRNA-SPLICING LIGASE COMPLEX SUBUNIT RTRAF binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000012155.3|UniProtKB=G3R8Y7 G3R8Y7 NEK6 PTHR43289:SF13 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE_THREONINE-PROTEIN KINASE NEK6 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;regulation of chromosome organization#GO:0033044;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular component organization#GO:0051128;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of mitotic cell cycle phase transition#GO:1901990 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000006581.3|UniProtKB=G3QUN2 G3QUN2 LRRC58 PTHR45752:SF13 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 58 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000168.3|UniProtKB=G3QD58 G3QD58 ALX1 PTHR24329:SF359 HOMEOBOX PROTEIN ARISTALESS ALX HOMEOBOX PROTEIN 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;neuron development#GO:0048666;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;skeletal system development#GO:0001501;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;embryo development#GO:0009790;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000010561.3|UniProtKB=G3R4T9 G3R4T9 ERLIN1 PTHR15351:SF2 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN-1 alcohol binding#GO:0043178;cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496;binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934 intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;SREBP signaling pathway#GO:0032933;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000027207.2|UniProtKB=G3SAK5 G3SAK5 METTL13 PTHR12176:SF78 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000036973.1|UniProtKB=G3QNG3 G3QNG3 ZNF84 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000023758.2|UniProtKB=G3SJ49 G3SJ49 KLK7 PTHR24271:SF45 KALLIKREIN-RELATED KALLIKREIN-7 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000009523.3|UniProtKB=G3RWH3 G3RWH3 FBRSL1 PTHR14429:SF20 FIBROSIN FAMILY MEMBER FIBROSIN-1-LIKE PROTEIN GORGO|Ensembl=ENSGGOG00000010265.3|UniProtKB=G3R429 G3R429 FRMD1 PTHR13429:SF7 FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY FERM DOMAIN-CONTAINING PROTEIN 1 protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000007610.3|UniProtKB=G3QXA8 G3QXA8 TMEM243 PTHR28603:SF1 TRANSMEMBRANE PROTEIN 243 TRANSMEMBRANE PROTEIN 243 GORGO|Ensembl=ENSGGOG00000011119.3|UniProtKB=G3R696 G3R696 SLC46A1 PTHR23507:SF2 ZGC:174356 PROTON-COUPLED FOLATE TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000242.3|UniProtKB=G3QDC5 G3QDC5 CNIH3 PTHR12290:SF12 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 3 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;endoplasmic reticulum subcompartment#GO:0098827;dendrite#GO:0030425;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;cell junction#GO:0030054;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000009533.3|UniProtKB=G3SK84 G3SK84 DNMT3B PTHR23068:SF9 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3B catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;nucleic acid binding#GO:0003676;binding#GO:0005488;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;DNA binding#GO:0003677 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA methyltransferase#PC00013 GORGO|Ensembl=ENSGGOG00000037651.1|UniProtKB=A0A2I2ZGB5 A0A2I2ZGB5 LOC101132617 PTHR26453:SF659 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008067.3|UniProtKB=G3QYG2 G3QYG2 MAN2B2 PTHR11607:SF28 ALPHA-MANNOSIDASE EPIDIDYMIS-SPECIFIC ALPHA-MANNOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000014407.3|UniProtKB=G3RES7 G3RES7 YTHDC2 PTHR18934:SF213 ATP-DEPENDENT RNA HELICASE 3'-5' RNA HELICASE YTHDC2 helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008499.3|UniProtKB=G3QZJ0 G3QZJ0 BRINP3 PTHR15564:SF2 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3 regulation of cell cycle#GO:0051726;central nervous system development#GO:0007417;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;generation of neurons#GO:0048699;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;negative regulation of cell cycle#GO:0045786;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of mitotic cell cycle#GO:0007346;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;negative regulation of cellular process#GO:0048523 dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000025717.2|UniProtKB=G3S0N6 G3S0N6 JSRP1 PTHR22397:SF2 JUNCTIONAL SARCOPLASMIC RETICULUM PROTEIN 1 JUNCTIONAL SARCOPLASMIC RETICULUM PROTEIN 1 skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;system process#GO:0003008;neuromuscular process#GO:0050905;muscle contraction#GO:0006936;nervous system process#GO:0050877 sarcoplasmic reticulum#GO:0016529;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;sarcoplasm#GO:0016528;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005134.3|UniProtKB=A0A2I2Z9C9 A0A2I2Z9C9 LENG8 PTHR12436:SF4 80 KDA MCM3-ASSOCIATED PROTEIN LEUKOCYTE RECEPTOR CLUSTER MEMBER 8 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005813.3|UniProtKB=G3QSP7 G3QSP7 LOC101148971 PTHR24291:SF9 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 27C1 oxidoreductase activity#GO:0016491;alcohol binding#GO:0043178;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;lipid binding#GO:0008289;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;organic acid binding#GO:0043177 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603 GORGO|Ensembl=ENSGGOG00000037054.1|UniProtKB=A0A2I2YQD0 A0A2I2YQD0 PTHR10064:SF2 60S RIBOSOMAL PROTEIN L22 LARGE RIBOSOMAL SUBUNIT PROTEIN EL22 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010529.3|UniProtKB=G3R4Q8 G3R4Q8 ZBTB2 PTHR24399:SF0 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 2 transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010816.3|UniProtKB=G3R5H8 G3R5H8 MUS81 PTHR13451:SF0 CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT MUS81 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518 negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;mitotic cell cycle process#GO:1903047;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;resolution of meiotic recombination intermediates#GO:0000712;double-strand break repair via break-induced replication#GO:0000727;DNA integrity checkpoint signaling#GO:0031570;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;intracellular signal transduction#GO:0035556;organelle fission#GO:0048285;cell communication#GO:0007154;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;reproductive process#GO:0022414;homologous recombination#GO:0035825;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;organelle organization#GO:0006996;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;negative regulation of mitotic cell cycle#GO:0045930;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cellular component organization#GO:0016043;meiosis I#GO:0007127;negative regulation of cell cycle phase transition#GO:1901988;meiotic cell cycle process#GO:1903046;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endonuclease complex#GO:1905348;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000003224.3|UniProtKB=G3QL28 G3QL28 NLRX1 PTHR24114:SF31 LEUCINE RICH REPEAT FAMILY PROTEIN NLR FAMILY MEMBER X1 GORGO|Ensembl=ENSGGOG00000027535.2|UniProtKB=G3RYW0 G3RYW0 KPNA2 PTHR23316:SF12 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008654.3|UniProtKB=G3S3J5 G3S3J5 LOC101137030 PTHR23425:SF16 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME A-RELATED transporter#PC00227 GORGO|Ensembl=ENSGGOG00000009498.3|UniProtKB=A0A2I2YX28 A0A2I2YX28 PTHR10351:SF28 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008222.3|UniProtKB=G3S3Y5 G3S3Y5 MYOD1 PTHR11534:SF2 MYOGENIC FACTOR MYOBLAST DETERMINATION PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;positive regulation of cell differentiation#GO:0045597;animal organ development#GO:0048513;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;skeletal muscle tissue development#GO:0007519;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;muscle tissue development#GO:0060537;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000000305.3|UniProtKB=A0A2I2YD08 A0A2I2YD08 PTHR11132:SF521 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E2A-RELATED active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000012717.3|UniProtKB=A0A2I2YSG0 A0A2I2YSG0 OBSCN PTHR35971:SF4 SI:DKEY-31G6.6 OBSCURIN catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 A band#GO:0031672;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;M band#GO:0031430;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;cell periphery#GO:0071944;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017;sarcolemma#GO:0042383 GORGO|Ensembl=ENSGGOG00000042726.1|UniProtKB=A0A2I2Z1R5 A0A2I2Z1R5 SPATA13 PTHR45834:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 13 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;filopodium assembly#GO:0046847;cellular process#GO:0009987;cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000006795.3|UniProtKB=G3QV88 G3QV88 ITGB7 PTHR10082:SF36 INTEGRIN BETA SUBUNIT INTEGRIN BETA-7 integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 leukocyte migration#GO:0050900;cell adhesion mediated by integrin#GO:0033627;cell surface receptor signaling pathway#GO:0007166;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;cell migration#GO:0016477;biological regulation#GO:0065007;immune system process#GO:0002376;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052 cell junction#GO:0030054;integrin complex#GO:0008305;anchoring junction#GO:0070161;signaling receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 GORGO|Ensembl=ENSGGOG00000040970.1|UniProtKB=A0A2I2Z8F6 A0A2I2Z8F6 LYNX1 PTHR16983:SF27 UPAR/LY6 DOMAIN-CONTAINING PROTEIN LY-6_NEUROTOXIN-LIKE PROTEIN 1 molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;neurotransmitter receptor regulator activity#GO:0099602;signaling receptor binding#GO:0005102;binding#GO:0005488;acetylcholine receptor inhibitor activity#GO:0030550;acetylcholine receptor regulator activity#GO:0030548 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;response to chemical#GO:0042221;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000000711.3|UniProtKB=G3QEK3 G3QEK3 PRDM7 PTHR14112:SF31 SYNOVIAL SARCOMA, X MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE PRDM7 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000003480.3|UniProtKB=G3QLQ5 G3QLQ5 POMC PTHR11416:SF7 PRO-OPIOMELANOCORTIN PRO-OPIOMELANOCORTIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell communication#GO:0007154;pigmentation#GO:0043473;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;cellular pigmentation#GO:0033059;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Cortocotropin releasing factor receptor signaling pathway#P04380>ACTH#P04453;Opioid proopiomelanocortin pathway#P05917>ACTH#P06008;Cortocotropin releasing factor receptor signaling pathway#P04380>proopiomelanocortin#G04671;Cortocotropin releasing factor receptor signaling pathway#P04380>beta-endorphin#P04455;Opioid proopiomelanocortin pathway#P05917>alpha-MSH#P06007;Opioid proopiomelanocortin pathway#P05917>beta-Endorphin#P06006;Opioid proopiomelanocortin pathway#P05917>proopiomelanocortin#P06010;Cortocotropin releasing factor receptor signaling pathway#P04380>proopiomelanocortin#P04452 GORGO|Ensembl=ENSGGOG00000036564.1|UniProtKB=A0A2I2ZCA2 A0A2I2ZCA2 HSBP1 PTHR19424:SF3 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to heat#GO:0009408;cellular response to heat#GO:0034605;heat acclimation#GO:0010286;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000004962.3|UniProtKB=G3QQJ7 G3QQJ7 EPS8L3 PTHR12287:SF22 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8-LIKE PROTEIN 3 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of cell projection organization#GO:0031344;regulation of response to stimulus#GO:0048583;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;regulation of signaling#GO:0023051;regulation of plasma membrane bounded cell projection assembly#GO:0120032;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of cellular component biogenesis#GO:0044087;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;cell projection membrane#GO:0031253;ruffle#GO:0001726;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001268.3|UniProtKB=G3QG03 G3QG03 WDR6 PTHR14344:SF3 WD REPEAT PROTEIN TRNA (34-2'-O)-METHYLTRANSFERASE REGULATOR WDR6 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002454.3|UniProtKB=G3QJ36 G3QJ36 STXBP2 PTHR11679:SF27 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 2 syntaxin binding#GO:0019905;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;establishment of protein localization#GO:0045184;synaptic signaling#GO:0099536;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;intracellular protein transport#GO:0006886;regulated exocytosis#GO:0045055;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;protein transport#GO:0015031;secretion by cell#GO:0032940;cellular localization#GO:0051641;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;vesicle localization#GO:0051648;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;intracellular transport#GO:0046907;calcium-ion regulated exocytosis#GO:0017156;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;signal release#GO:0023061 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000043110.1|UniProtKB=G3SCE6 G3SCE6 LOC101150282 PTHR48018:SF102 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5B3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016599.3|UniProtKB=G3RKC9 G3RKC9 SLX4 PTHR21541:SF3 BTB POZ DOMAIN CONTAINING 12 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4 meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;resolution of meiotic recombination intermediates#GO:0000712;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;organelle fission#GO:0048285;cell cycle#GO:0007049;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;reproductive process#GO:0022414;homologous recombination#GO:0035825 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000010479.3|UniProtKB=G3R4M6 G3R4M6 PTHR22762:SF122 ALPHA-GLUCOSIDASE MALTASE-GLUCOAMYLASE 2-RELATED catalytic activity#GO:0003824;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;alpha-glucosidase activity#GO:0090599;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 glucosidase#PC00108 GORGO|Ensembl=ENSGGOG00000013314.3|UniProtKB=G3RBX5 G3RBX5 SLC38A5 PTHR22950:SF74 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 5 L-amino acid transmembrane transporter activity#GO:0015179;glycine transmembrane transporter activity#GO:0015187;neutral L-amino acid transmembrane transporter activity#GO:0015175;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 glycine transport#GO:0015816;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 GORGO|Ensembl=ENSGGOG00000004173.3|UniProtKB=G3QNI0 G3QNI0 ACCSL PTHR43795:SF1 BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED INACTIVE 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE-LIKE PROTEIN 2-RELATED catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001049.3|UniProtKB=A0A2I2Z2Z7 A0A2I2Z2Z7 MPP1 PTHR23122:SF37 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK 55 KDA ERYTHROCYTE MEMBRANE PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of neurotransmitter secretion#GO:0046928;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;macromolecule localization#GO:0033036;regulation of localization#GO:0032879;regulation of transport#GO:0051049;intracellular protein localization#GO:0008104 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039613.1|UniProtKB=A0A2I2ZVJ6 A0A2I2ZVJ6 ZFP69B PTHR24381:SF135 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 69 HOMOLOG B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000014216.3|UniProtKB=G3RE85 G3RE85 GIMAP5 PTHR10903:SF69 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 5 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000005093.3|UniProtKB=G3QQW6 G3QQW6 PEG3 PTHR24381:SF293 ZINC FINGER PROTEIN PATERNALLY-EXPRESSED GENE 3 PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012927.3|UniProtKB=G3RAX5 G3RAX5 NSG2 PTHR28546:SF2 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2 biological regulation#GO:0065007;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;macromolecule metabolic process#GO:0043170;transport#GO:0006810;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;metabolic process#GO:0008152 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;glutamatergic synapse#GO:0098978;endomembrane system#GO:0012505;late endosome#GO:0005770;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;cell junction#GO:0030054;vesicle#GO:0031982;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;postsynaptic membrane#GO:0045211;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011495.4|UniProtKB=G3R795 G3R795 CACNA2D3 PTHR10166:SF25 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-3 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267 calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012145.3|UniProtKB=G3R8Y6 G3R8Y6 IL17RE PTHR15583:SF5 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR E transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013966.3|UniProtKB=G3RDM0 G3RDM0 RPN1 PTHR21049:SF0 RIBOPHORIN I DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1 protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004212.3|UniProtKB=G3QNL2 G3QNL2 SNX30 PTHR45949:SF1 SORTING NEXIN-4 SORTING NEXIN-30 localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;endocytic recycling#GO:0032456;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;intracellular transport#GO:0046907;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;mitophagy#GO:0000423;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;reticulophagy#GO:0061709;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;macroautophagy#GO:0016236 phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000038385.1|UniProtKB=A0A2I2YY57 A0A2I2YY57 PTHR23235:SF93 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007066.3|UniProtKB=G3QVX3 G3QVX3 FGF17 PTHR11486:SF71 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 17 growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to fibroblast growth factor#GO:0071774;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000009843.3|UniProtKB=G3R2Z7 G3R2Z7 PTHR23299:SF42 METALLOTHIONEIN SUBFAMILY NOT NAMED binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;inorganic ion homeostasis#GO:0098771;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;detoxification of inorganic compound#GO:0061687;response to stress#GO:0006950;detoxification#GO:0098754;response to chemical#GO:0042221;response to metal ion#GO:0010038;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;response to cadmium ion#GO:0046686;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000001933.3|UniProtKB=G3RTQ9 G3RTQ9 GREB1L PTHR15720:SF12 GREB1-RELATED GREB1-LIKE PROTEIN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;system development#GO:0048731;renal system development#GO:0072001;kidney development#GO:0001822;anatomical structure morphogenesis#GO:0009653;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelium development#GO:0060429 GORGO|Ensembl=ENSGGOG00000028255.2|UniProtKB=G3RTZ2 G3RTZ2 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000028478.2|UniProtKB=G3S1I1 G3S1I1 GADD45B PTHR10411:SF5 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 BETA molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 p53 pathway#P00059>GADD45#P04626;p53 pathway#P00059>GADD45#G01575 GORGO|Ensembl=ENSGGOG00000034885.2|UniProtKB=A0A2I2ZVT8 A0A2I2ZVT8 EOGT PTHR20961:SF148 GLYCOSYLTRANSFERASE EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000044194.1|UniProtKB=A0A2I2Y2U6 A0A2I2Y2U6 ZCCHC12 PTHR23095:SF18 PARANEOPLASTIC ANTIGEN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 12 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000025934.2|UniProtKB=G3SCJ4 G3SCJ4 PTHR13718:SF93 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000042351.1|UniProtKB=G3SFB0 G3SFB0 PTHR20981:SF24 60S RIBOSOMAL PROTEIN L21 60S RIBOSOMAL PROTEIN L21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000002565.3|UniProtKB=G3QJD1 G3QJD1 MED7 PTHR21428:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000014262.3|UniProtKB=G3RED3 G3RED3 ECI1 PTHR11941:SF178 ENOYL-COA HYDRATASE-RELATED ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity#GO:0003824 fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 lyase#PC00144;hydratase#PC00120;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003179.3|UniProtKB=A0A2I2ZCC3 A0A2I2ZCC3 ANKDD1A PTHR24125:SF0 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1A GORGO|Ensembl=ENSGGOG00000007537.3|UniProtKB=G3QX50 G3QX50 TBL1X PTHR22846:SF52 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1X double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transcription repressor complex#GO:0017053;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Wnt signaling pathway#P00057>Ebi#P01453 GORGO|Ensembl=ENSGGOG00000009001.3|UniProtKB=G3R0V3 G3R0V3 TEX30 PTHR13136:SF11 TESTIS DEVELOPMENT PROTEIN PRTD TESTIS-EXPRESSED PROTEIN 30 GORGO|Ensembl=ENSGGOG00000012079.3|UniProtKB=A0A2I2YBD9 A0A2I2YBD9 KNCN PTHR38497:SF1 KINOCILIN KINOCILIN membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;cortical cytoskeleton#GO:0030863;cell body#GO:0044297;cell cortex#GO:0005938;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000012986.3|UniProtKB=A0A2I2ZHE1 A0A2I2ZHE1 GZMB PTHR24271:SF81 KALLIKREIN-RELATED GRANZYME B catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;signal transduction#GO:0007165;protein maturation#GO:0051604;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;cell communication#GO:0007154;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 Apoptosis signaling pathway#P00006>Granzyme B#P00265 GORGO|Ensembl=ENSGGOG00000006035.3|UniProtKB=G3QT92 G3QT92 CMTM8 PTHR22776:SF10 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 8 regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000028284.2|UniProtKB=G3SH71 G3SH71 ARRDC5 PTHR11188:SF172 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 5 cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000003384.3|UniProtKB=G3QLI1 G3QLI1 CLASRP PTHR13161:SF4 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT CLK4-ASSOCIATING SERINE_ARGININE RICH PROTEIN RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000009594.3|UniProtKB=A0A2I2ZIQ9 A0A2I2ZIQ9 RNF186 PTHR22791:SF28 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF186 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000038908.1|UniProtKB=G3SAN7 G3SAN7 ZNF83 PTHR23232:SF171 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010976.3|UniProtKB=G3R5W3 G3R5W3 LOC101136745 PTHR26453:SF690 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011824.3|UniProtKB=G3R844 G3R844 PTHR10728:SF24 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 EPSILON binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;hydrolase activity, acting on ester bonds#GO:0016788 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;glycerophospholipid catabolic process#GO:0046475;organophosphate catabolic process#GO:0046434;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000000490.3|UniProtKB=G3QDZ7 G3QDZ7 TMEM150B PTHR21324:SF3 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED MODULATOR OF MACROAUTOPHAGY TMEM150B cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040042.1|UniProtKB=A0A2I2Y6P2 A0A2I2Y6P2 PTHR23267:SF373 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-5 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000002019.3|UniProtKB=G3QI01 G3QI01 CLIP1 PTHR18916:SF44 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 1 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 regulation of microtubule-based process#GO:0032886;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of microtubule polymerization#GO:0031113;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cytoplasmic microtubule organization#GO:0031122;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;cellular component organization or biogenesis#GO:0071840;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of protein polymerization#GO:0032273;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;microtubule end#GO:1990752;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000002753.3|UniProtKB=G3QJW0 G3QJW0 PIGL PTHR12993:SF11 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE catalytic activity#GO:0003824;deacylase activity#GO:0160215;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 deacetylase#PC00087 GORGO|Ensembl=ENSGGOG00000009600.3|UniProtKB=G3SBW5 G3SBW5 PPP1R13B PTHR24131:SF5 APOPTOSIS-STIMULATING OF P53 PROTEIN APOPTOSIS-STIMULATING OF P53 PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cell death#GO:0008219;programmed cell death#GO:0012501;signaling#GO:0023052;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;regulation of cellular process#GO:0050794;signal transduction by p53 class mediator#GO:0072331;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;apoptotic signaling pathway#GO:0097190 intracellular organelle#GO:0043229;cell junction#GO:0030054;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell-cell junction#GO:0005911;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000008088.3|UniProtKB=A0A2I2YFP3 A0A2I2YFP3 EPC1 PTHR14898:SF6 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB HOMOLOG 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010462.3|UniProtKB=G3R4J9 G3R4J9 PTHR18945:SF385 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-4 channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594 system process#GO:0003008;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;synaptic transmission, cholinergic#GO:0007271;response to nitrogen compound#GO:1901698;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;neuromuscular synaptic transmission#GO:0007274;response to chemical#GO:0042221;cellular process#GO:0009987;renal system process#GO:0003014;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotine pharmacodynamics pathway#P06587>CHRNB4#P06610;Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095 GORGO|Ensembl=ENSGGOG00000006325.3|UniProtKB=A0A2I2YSW5 A0A2I2YSW5 NUDT5 PTHR11839:SF24 UDP/ADP-SUGAR PYROPHOSPHATASE ADP-SUGAR PYROPHOSPHATASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 pyrophosphatase#PC00196;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010402.3|UniProtKB=G3R4F8 G3R4F8 ALG13 PTHR12419:SF58 OTU DOMAIN CONTAINING PROTEIN BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE TRANSFERASE AND DEUBIQUITINASE ALG13 ISOFORM X1 catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000036844.1|UniProtKB=A0A2I2Y2A4 A0A2I2Y2A4 CX3CR1 PTHR10489:SF955 CELL ADHESION MOLECULE CX3C CHEMOKINE RECEPTOR 1 molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000015091.3|UniProtKB=G3RGI5 G3RGI5 FAP PTHR11731:SF136 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED PROLYL ENDOPEPTIDASE FAP catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000007392.3|UniProtKB=G3QWR8 G3QWR8 PSMB11 PTHR11599:SF48 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-11 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004854.3|UniProtKB=G3QQ92 G3QQ92 STK35 PTHR11042:SF59 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED SERINE_THREONINE-PROTEIN KINASE 35 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000014328.3|UniProtKB=G3REI4 G3REI4 ALKAL2 PTHR28676:SF2 ALK AND LTK LIGAND 2-RELATED ALK AND LTK LIGAND 2 kinase activator activity#GO:0019209;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;molecular function regulator activity#GO:0098772;receptor tyrosine kinase binding#GO:0030971;protein kinase activator activity#GO:0030295;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408 GORGO|Ensembl=ENSGGOG00000013579.3|UniProtKB=A0A2I2YN84 A0A2I2YN84 MROH1 PTHR23120:SF44 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004495.3|UniProtKB=G3QPB7 G3QPB7 SYT2 PTHR10024:SF223 SYNAPTOTAGMIN SYNAPTOTAGMIN-2 molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;secretion#GO:0046903;regulation of exocytosis#GO:0017157;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of neurotransmitter secretion#GO:0046928;export from cell#GO:0140352;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of neurotransmitter transport#GO:0051588;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;synaptic signaling#GO:0099536;positive regulation of biological process#GO:0048518;synaptic vesicle exocytosis#GO:0016079;positive regulation of transport#GO:0051050;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887 axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular vesicle#GO:0097708;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 GORGO|Ensembl=ENSGGOG00000006225.3|UniProtKB=G3QTR1 G3QTR1 PHOX2B PTHR24329:SF301 HOMEOBOX PROTEIN ARISTALESS PAIRED MESODERM HOMEOBOX PROTEIN 2B double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000016285.3|UniProtKB=G3SJ46 G3SJ46 SPOPL PTHR24413:SF91 SPECKLE-TYPE POZ PROTEIN SPECKLE-TYPE POZ PROTEIN-LIKE enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000027350.2|UniProtKB=A0A2I2Y4S7 A0A2I2Y4S7 PTHR21496:SF0 FERREDOXIN-RELATED RIESKE DOMAIN-CONTAINING PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000040001.1|UniProtKB=A0A2I2ZGZ6 A0A2I2ZGZ6 PTHR11818:SF142 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN E-RELATED structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;sensory system development#GO:0048880;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000009092.3|UniProtKB=G3S4I7 G3S4I7 COQ10A PTHR12901:SF8 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG A, MITOCHONDRIAL organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006671.3|UniProtKB=G3SA66 G3SA66 FAIM2 PTHR23291:SF18 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 2 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;negative regulation of neuron apoptotic process#GO:0043524;negative regulation of signal transduction#GO:0009968;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;response to unfolded protein#GO:0006986;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to topologically incorrect protein#GO:0035967;regulation of apoptotic signaling pathway#GO:2001233;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040967.1|UniProtKB=A0A2I2ZYV4 A0A2I2ZYV4 PTHR43139:SF26 SI:DKEY-122A22.2 AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000036674.1|UniProtKB=A0A2I2YH02 A0A2I2YH02 LOC101147448 PTHR35268:SF1 PROTEIN CCSMST1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 4 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013408.3|UniProtKB=G3RC59 G3RC59 LOC101147502 PTHR14095:SF1 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT BETA protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007715.3|UniProtKB=G3QXK0 G3QXK0 AIRIM PTHR16234:SF5 SIMILAR TO HYPOTHETICAL PROTEIN FLJ20508 AFG2-INTERACTING RIBOSOME MATURATION FACTOR nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000004186.3|UniProtKB=G3QNJ1 G3QNJ1 ZNF644 PTHR24396:SF25 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 644 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000028233.2|UniProtKB=G3SIP8 G3SIP8 PTHR13296:SF3 BCAS2 PROTEIN SUBFAMILY NOT NAMED RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000027485.2|UniProtKB=G3RVR5 G3RVR5 LOC101151592 PTHR14224:SF79 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 18-RELATED ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014206.3|UniProtKB=G3RE79 G3RE79 ATF3 PTHR23351:SF23 FOS TRANSCRIPTION FACTOR-RELATED CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#G06902;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#G06689;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#P06821 GORGO|Ensembl=ENSGGOG00000003279.3|UniProtKB=G3SFF7 G3SFF7 RAB37 PTHR47977:SF60 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-26 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000036743.1|UniProtKB=A0A2I2Y6D0 A0A2I2Y6D0 PTHR11937:SF54 ACTIN ACTIN-LIKE 11 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000011081.3|UniProtKB=G3R662 G3R662 MICOS13 PTHR31816:SF3 MICOS COMPLEX SUBUNIT MIC13 MICOS COMPLEX SUBUNIT MIC13 mitochondrion organization#GO:0007005;membrane organization#GO:0061024;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane contact site#GO:0044232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000043740.1|UniProtKB=A0A2I2YJI8 A0A2I2YJI8 PTHR23267:SF510 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR DELTA VARIABLE 1 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014690.3|UniProtKB=G3RFG7 G3RFG7 AGXT PTHR21152:SF40 AMINOTRANSFERASE CLASS V ALANINE--GLYOXYLATE AMINOTRANSFERASE transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740 carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;carboxylic acid catabolic process#GO:0046395;aldehyde catabolic process#GO:0046185;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;monocarboxylic acid catabolic process#GO:0072329;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000003077.3|UniProtKB=G3QKP4 G3QKP4 GNA15 PTHR10218:SF217 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-15 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of membrane potential#GO:0042391;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;action potential#GO:0001508;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cellular anatomical structure#GO:0110165 heterotrimeric G-protein#PC00117;G-protein#PC00020 Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Wnt signaling pathway#P00057>Galpha#P01451;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826 GORGO|Ensembl=ENSGGOG00000024547.2|UniProtKB=G3S7Z5 G3S7Z5 ZNF695 PTHR24379:SF131 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 712 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000036755.1|UniProtKB=A0A2I2YIQ7 A0A2I2YIQ7 PTHR14964:SF4 NUCLEAR RECEPTOR BINDING FACTOR 2 NUCLEAR RECEPTOR BINDING FACTOR 2 catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;metabolic process#GO:0008152;cellular process#GO:0009987;autophagy#GO:0006914 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000028272.2|UniProtKB=G3RYF7 G3RYF7 TFDP3 PTHR12548:SF13 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP FAMILY MEMBER 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000028114.2|UniProtKB=G3SDV9 G3SDV9 NPY PTHR10533:SF5 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PRO-NEUROPEPTIDE Y G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;neuropeptide hormone activity#GO:0005184;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;feeding behavior#GO:0007631 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000006547.3|UniProtKB=G3QUK2 G3QUK2 DHCR7 PTHR21257:SF57 DELTA(14)-STEROL REDUCTASE 7-DEHYDROCHOLESTEROL REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000003787.3|UniProtKB=G3RM29 G3RM29 TP53BP2 PTHR24131:SF8 APOPTOSIS-STIMULATING OF P53 PROTEIN APOPTOSIS-STIMULATING OF P53 PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cell death#GO:0008219;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;intracellular signal transduction#GO:0035556;signal transduction by p53 class mediator#GO:0072331;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;apoptotic signaling pathway#GO:0097190 adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;intracellular organelle#GO:0043229;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cell-cell junction#GO:0005911 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000006116.3|UniProtKB=G3QTG2 G3QTG2 PTHR10489:SF627 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8 molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;chemotaxis#GO:0006935;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000037505.1|UniProtKB=A0A2I2Z3G3 A0A2I2Z3G3 LOC129528620 PTHR11515:SF25 GLYCOPROTEIN HORMONE BETA CHAIN CHORIOGONADOTROPIN SUBUNIT BETA 3-RELATED signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 anatomical structure development#GO:0048856;cell communication#GO:0007154;reproductive system development#GO:0061458;female gonad development#GO:0008585;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;reproductive process#GO:0022414;reproductive structure development#GO:0048608;signaling#GO:0023052;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;multicellular organismal process#GO:0032501;gonad development#GO:0008406;biological regulation#GO:0065007;cellular process#GO:0009987;sex differentiation#GO:0007548;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000008043.3|UniProtKB=G3QYD4 G3QYD4 KRAS PTHR24070:SF388 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE KRAS hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;Ras protein signal transduction#GO:0007265;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;Integrin signalling pathway#P00034>Ras#P00916;Ras Pathway#P04393>Ras#P04547;EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;FGF signaling pathway#P00021>Ras#P00633;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;p53 pathway feedback loops 2#P04398>Ras#P04651;Angiogenesis#P00005>Ras#P00238;PI3 kinase pathway#P00048>Ras#P01182 GORGO|Ensembl=ENSGGOG00000012974.3|UniProtKB=A0A2I2ZYV0 A0A2I2ZYV0 ATP6V0D1 PTHR11028:SF3 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626 biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular transport#GO:0046907;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular localization#GO:0051641;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885 organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;endomembrane system#GO:0012505;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex#GO:0016469;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;lytic vacuole#GO:0000323;lysosomal membrane#GO:0005765;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;endosome#GO:0005768;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;ATPase dependent transmembrane transport complex#GO:0098533;early endosome#GO:0005769;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000001310.3|UniProtKB=G3QG40 G3QG40 LSM6 PTHR11021:SF1 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;nucleolus#GO:0005730;P-body#GO:0000932;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;U4/U6 x U5 tri-snRNP complex#GO:0046540;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;U6 snRNP#GO:0005688 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000027391.2|UniProtKB=G3RYG4 G3RYG4 YEATS4 PTHR47573:SF1 PROTEIN AF-9 HOMOLOG PROTEIN AF-9 HOMOLOG GORGO|Ensembl=ENSGGOG00000005721.3|UniProtKB=A0A2I2ZJK2 A0A2I2ZJK2 LOC101130554 PTHR46501:SF2 MYOMEGALIN MYOMEGALIN centrosome cycle#GO:0007098;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;cell cycle#GO:0007049;cellular component organization#GO:0016043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000003243.3|UniProtKB=G3QL45 G3QL45 LOC101131774 PTHR24291:SF6 CYTOCHROME P450 FAMILY 4 STEROL 26-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;vitamin D metabolic process#GO:0042359;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603 GORGO|Ensembl=ENSGGOG00000004995.3|UniProtKB=G3S3W6 G3S3W6 ALDH3B1 PTHR43570:SF2 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER B1 aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000026549.2|UniProtKB=A0A2I2YGL8 A0A2I2YGL8 BCL6 PTHR24409:SF392 ZINC FINGER PROTEIN 142 BCL6 TRANSCRIPTION REPRESSOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000028079.2|UniProtKB=A0A2I2Z0M3 A0A2I2Z0M3 SLC36A4 PTHR22950:SF190 AMINO ACID TRANSPORTER NEUTRAL AMINO ACID UNIPORTER 4 neutral L-amino acid transmembrane transporter activity#GO:0015175;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;localization#GO:0051179;amino acid transport#GO:0006865;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;alanine transport#GO:0032328;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229 amino acid transporter#PC00046;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000001740.3|UniProtKB=G3QH93 G3QH93 GDPD2 PTHR23344:SF1 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 3 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000016950.3|UniProtKB=G3RLA2 G3RLA2 ZSCAN25 PTHR23226:SF1 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 25 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008535.3|UniProtKB=G3QZM9 G3QZM9 CIMAP3 PTHR31508:SF2 PROTEIN PITCHFORK CILIARY MICROTUBULE-ASSOCIATED PROTEIN 3 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;regulation of cell projection organization#GO:0031344;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;organelle organization#GO:0006996 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000014890.3|UniProtKB=A0A2I2Z436 A0A2I2Z436 PKIB PTHR15416:SF6 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR BETA enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 kinase modulator#PC00140;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000007724.3|UniProtKB=G3QXL6 G3QXL6 EPHA10 PTHR24416:SF618 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 5 catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000017120.3|UniProtKB=G3RLQ0 G3RLQ0 OLFM3 PTHR23192:SF36 OLFACTOMEDIN-RELATED NOELIN-3 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000004145.3|UniProtKB=G3QNF2 G3QNF2 WSCD1 PTHR45964:SF8 WSCD FAMILY MEMBER CG9164 SIALATE:O-SULFOTRANSFERASE 1 GORGO|Ensembl=ENSGGOG00000040999.1|UniProtKB=A0A2I2Z735 A0A2I2Z735 NOA1 PTHR46406:SF1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 protein-containing complex organization#GO:0043933;mitochondrial ribosome assembly#GO:0061668;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-RNA complex assembly#GO:0022618;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007720.3|UniProtKB=A0A2I2Z329 A0A2I2Z329 ADAMTS4 PTHR13723:SF38 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 4 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000015956.3|UniProtKB=G3RR67 G3RR67 WDR43 PTHR44267:SF1 WD REPEAT-CONTAINING PROTEIN 43 WD REPEAT-CONTAINING PROTEIN 43 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000254.3|UniProtKB=G3QDD7 G3QDD7 SLC13A5 PTHR10283:SF109 SOLUTE CARRIER FAMILY 13 MEMBER NA(+)_CITRATE COTRANSPORTER citrate transmembrane transporter activity#GO:0015137;symporter activity#GO:0015293;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;C4-dicarboxylate transmembrane transporter activity#GO:0015556;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;solute:monoatomic cation symporter activity#GO:0015294;succinate transmembrane transporter activity#GO:0015141;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081 cellular process#GO:0009987;succinate transport#GO:0015744;dicarboxylic acid transport#GO:0006835;citrate transport#GO:0015746;tricarboxylic acid transport#GO:0006842;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006179.3|UniProtKB=G3QTL7 G3QTL7 FUT11 PTHR11929:SF198 ALPHA- 1,3 -FUCOSYLTRANSFERASE GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 4 alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000016820.3|UniProtKB=G3RKX9 G3RKX9 EGFL7 PTHR14949:SF21 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 7 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 developmental process#GO:0032502;vasculature development#GO:0001944;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;tube development#GO:0035295;multicellular organismal process#GO:0032501;vasculogenesis#GO:0001570;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;circulatory system development#GO:0072359;cell differentiation#GO:0030154 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000014996.3|UniProtKB=G3SJ16 G3SJ16 TRIM45 PTHR25462:SF291 BONUS, ISOFORM C-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM45 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000006632.3|UniProtKB=G3RPJ1 G3RPJ1 WBP1L PTHR16209:SF4 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN BINDING PROTEIN 1-LIKE cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;response to chemokine#GO:1990868;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;response to peptide#GO:1901652;G protein-coupled receptor signaling pathway#GO:0007186;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to chemokine#GO:1990869;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345 GORGO|Ensembl=ENSGGOG00000003341.3|UniProtKB=G3QLD5 G3QLD5 STMN4 PTHR10104:SF6 STATHMIN STATHMIN-4 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 neuron development#GO:0048666;cellular component disassembly#GO:0022411;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;regulation of microtubule-based process#GO:0032886;protein-containing complex disassembly#GO:0032984;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;neurogenesis#GO:0022008;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular developmental process#GO:0048869;developmental process#GO:0032502;protein depolymerization#GO:0051261;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;microtubule polymerization or depolymerization#GO:0031109 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 Cytoskeletal regulation by Rho GTPase#P00016>Op18/stathmin#P00513 GORGO|Ensembl=ENSGGOG00000006952.3|UniProtKB=G3QVM4 G3QVM4 TSPAN18 PTHR19282:SF249 TETRASPANIN TETRASPANIN-18 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013108.3|UniProtKB=G3RBE0 G3RBE0 TTLL3 PTHR45870:SF1 TUBULIN MONOGLYCYLASE TTLL3 TUBULIN MONOGLYCYLASE TTLL3 catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;ligase activity, forming carbon-nitrogen bonds#GO:0016879 sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;gamete generation#GO:0007276;cell projection organization#GO:0030030;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;spermatogenesis#GO:0007283;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000006198.3|UniProtKB=G3QTN4 G3QTN4 SLC25A1 PTHR45788:SF4 SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL active transmembrane transporter activity#GO:0022804;citrate transmembrane transporter activity#GO:0015137;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;citrate transport#GO:0015746;tricarboxylic acid transport#GO:0006842;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000022924.2|UniProtKB=G3RS79 G3RS79 IRGM PTHR32341:SF9 INTERFERON-INDUCIBLE GTPASE IMMUNITY-RELATED GTPASE FAMILY M PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 cellular response to cytokine stimulus#GO:0071345;cellular component organization#GO:0016043;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune system process#GO:0002376;response to peptide#GO:1901652;process utilizing autophagic mechanism#GO:0061919;defense response to symbiont#GO:0140546;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;response to biotic stimulus#GO:0009607;organelle organization#GO:0006996;response to stress#GO:0006950;cellular component assembly#GO:0022607;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;response to external biotic stimulus#GO:0043207;catabolic process#GO:0009056;organelle assembly#GO:0070925;vacuole organization#GO:0007033;immune response#GO:0006955;response to other organism#GO:0051707;macroautophagy#GO:0016236;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000005451.3|UniProtKB=G3QRS6 G3QRS6 FGD2 PTHR12673:SF82 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 2 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;filopodium assembly#GO:0046847;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000027953.2|UniProtKB=G3RLZ6 G3RLZ6 LOC101146261 PTHR11442:SF87 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ALPHA 2 tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488 establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;cellular process#GO:0009987;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;localization#GO:0051179;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;globin#PC00107 GORGO|Ensembl=ENSGGOG00000003253.3|UniProtKB=G3QL60 G3QL60 CDK5RAP1 PTHR43020:SF2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1 MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a tRNA#GO:0140101;iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488 mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA modification#GO:1900864;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;mitochondrial RNA metabolic process#GO:0000959 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000006398.3|UniProtKB=A0A2I2ZC42 A0A2I2ZC42 STARD13 PTHR12659:SF6 RHO-TYPE GTPASE ACTIVATING PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 13 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;actin cytoskeleton organization#GO:0030036;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular process#GO:0009987;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000004018.3|UniProtKB=G3QN37 G3QN37 SMAP2 PTHR45705:SF4 FI20236P1 STROMAL MEMBRANE-ASSOCIATED PROTEIN 2 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000012336.3|UniProtKB=G3R9E9 G3R9E9 MRPL40 PTHR13359:SF2 39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML40 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000211.3|UniProtKB=G3QD97 G3QD97 FLACC1 PTHR21707:SF42 FLAGELLUM-ASSOCIATED COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FLAGELLUM-ASSOCIATED COILED-COIL DOMAIN-CONTAINING PROTEIN 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000034945.2|UniProtKB=G3SKM1 G3SKM1 PRPSAP1 PTHR10210:SF28 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000040059.1|UniProtKB=G3RXP1 G3RXP1 LOC101130238 PTHR23262:SF7 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 2-2-RELATED structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000008638.3|UniProtKB=A0A2I2Z7J1 A0A2I2Z7J1 TMEM39B PTHR12995:SF2 FI21814P1 TRANSMEMBRANE PROTEIN 39B cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000016168.3|UniProtKB=A0A2I2ZT35 A0A2I2ZT35 FNIP1 PTHR21634:SF12 RE13835P FOLLICULIN-INTERACTING PROTEIN 1 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002367.3|UniProtKB=G3QIW0 G3QIW0 TINAG PTHR12411:SF274 CYSTEINE PROTEASE FAMILY C1-RELATED TUBULOINTERSTITIAL NEPHRITIS ANTIGEN cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000043063.1|UniProtKB=A0A2I2YWK8 A0A2I2YWK8 PTHR21642:SF2 CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN-LIKE anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;circulatory system development#GO:0072359;heart development#GO:0007507;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513 GORGO|Ensembl=ENSGGOG00000012274.3|UniProtKB=G3R995 G3R995 NCEH1 PTHR23024:SF108 ARYLACETAMIDE DEACETYLASE NEUTRAL CHOLESTEROL ESTER HYDROLASE 1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 membrane#GO:0016020;cellular anatomical structure#GO:0110165 deacetylase#PC00087 GORGO|Ensembl=ENSGGOG00000012780.3|UniProtKB=A0A2I2Z554 A0A2I2Z554 SEPTIN9 PTHR18884:SF47 SEPTIN SEPTIN-9 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cell cortex#GO:0005938;cell periphery#GO:0071944 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000014144.3|UniProtKB=G3RE37 G3RE37 NSD2 PTHR22884:SF293 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE NSD2 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000025513.2|UniProtKB=G3SC74 G3SC74 LOC101123774 PTHR11620:SF104 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 N-TERMINAL DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008221.3|UniProtKB=G3QYU5 G3QYU5 TGFBRAP1 PTHR12894:SF51 CNH DOMAIN CONTAINING TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1 transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;vesicle organization#GO:0016050;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;vesicle fusion#GO:0006906;organelle membrane fusion#GO:0090174 vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000013118.3|UniProtKB=G3RBE2 G3RBE2 TSSK3 PTHR24343:SF74 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 3 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular process#GO:0009987;male gamete generation#GO:0048232 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Gene=GLUD2|UniProtKB=Q64I01 Q64I01 GLUD2 PTHR11606:SF15 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE 2, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 GORGO|Ensembl=ENSGGOG00000034994.2|UniProtKB=A0A2I2ZGP7 A0A2I2ZGP7 FCHSD2 PTHR15735:SF11 FCH AND DOUBLE SH3 DOMAINS PROTEIN F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 2 phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;regulation of actin filament organization#GO:0110053;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;regulation of actin filament-based process#GO:0032970;transport#GO:0006810;regulation of cytoskeleton organization#GO:0051493;anterograde trans-synaptic signaling#GO:0098916;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;regulation of supramolecular fiber organization#GO:1902903;clathrin-dependent endocytosis#GO:0072583;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;regulation of actin cytoskeleton organization#GO:0032956;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;regulation of anatomical structure size#GO:0090066;neuromuscular synaptic transmission#GO:0007274;regulation of cellular component organization#GO:0051128;endocytosis#GO:0006897;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;neuromuscular junction#GO:0031594;recycling endosome#GO:0055037;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000006687.3|UniProtKB=G3QUY0 G3QUY0 ITPRIPL2 PTHR10656:SF9 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN-LIKE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220;nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000014183.3|UniProtKB=A0A2I2Z3M4 A0A2I2Z3M4 ELF3 PTHR11849:SF13 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000039039.1|UniProtKB=A0A2I2YYT3 A0A2I2YYT3 PTHR23411:SF39 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;antigen binding#GO:0003823;protein binding#GO:0005515 response to bacterium#GO:0009617;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;defense response#GO:0006952;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;response to other organism#GO:0051707;adaptive immune response#GO:0002250;immune response#GO:0006955;complement activation#GO:0006956;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;antibacterial humoral response#GO:0019731;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;immune effector process#GO:0002252;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000012565.3|UniProtKB=G3RA11 G3RA11 FADS1 PTHR19353:SF57 FATTY ACID DESATURASE 2 ACYL-COA (8-3)-DESATURASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016667.3|UniProtKB=G3RKJ4 G3RKJ4 EMX2 PTHR24339:SF25 HOMEOBOX PROTEIN EMX-RELATED HOMEOBOX PROTEIN EMX2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;head development#GO:0060322;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000042846.1|UniProtKB=A0A2I2ZQI3 A0A2I2ZQI3 PTHR16476:SF3 FAMILY WITH SEQUENCE SIMILARITY 216 MEMBER A PROTEIN FAM216B GORGO|Ensembl=ENSGGOG00000000733.3|UniProtKB=A0A2I2YQF3 A0A2I2YQF3 QKI PTHR11208:SF42 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING RNA-BINDING PROTEIN QKI RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000039592.1|UniProtKB=G3RV99 G3RV99 HMX2 PTHR46110:SF4 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000010276.3|UniProtKB=G3R439 G3R439 HES5 PTHR10985:SF159 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;pattern specification process#GO:0007389;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 GORGO|Ensembl=ENSGGOG00000007713.3|UniProtKB=A0A2I2Z7H5 A0A2I2Z7H5 PTHR24390:SF124 ZINC FINGER PROTEIN TISSUE-RESIDENT T-CELL TRANSCRIPTION REGULATOR PROTEIN ZNF683 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010175.3|UniProtKB=G3R3W7 G3R3W7 RNF213 PTHR22605:SF16 RZ-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF213 ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;negative regulation of cell communication#GO:0010648;angiogenesis#GO:0001525;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;animal gross anatomical part developmental process#GO:0160108;negative regulation of signaling#GO:0023057;sprouting angiogenesis#GO:0002040;regulation of Wnt signaling pathway#GO:0030111;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;negative regulation of biological process#GO:0048519;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;tube development#GO:0035295;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;multicellular organismal process#GO:0032501;system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014794.3|UniProtKB=G3RFQ7 G3RFQ7 TMEM81 PTHR35670:SF1 TRANSMEMBRANE PROTEIN 81 TRANSMEMBRANE PROTEIN 81 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell recognition#GO:0008037;sexual reproduction#GO:0019953;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988;cellular process#GO:0009987;single fertilization#GO:0007338;reproductive process#GO:0022414;fertilization#GO:0009566 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000009015.3|UniProtKB=G3R0W7 G3R0W7 PLA2G2D PTHR11716:SF57 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP IID SECRETORY PHOSPHOLIPASE A2 phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289 negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;negative regulation of leukocyte cell-cell adhesion#GO:1903038;phospholipid metabolic process#GO:0006644;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of T cell proliferation#GO:0042129;phosphatidylglycerol metabolic process#GO:0046471;lipid metabolic process#GO:0006629;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cell activation#GO:0050866;negative regulation of cell population proliferation#GO:0008285;organophosphate metabolic process#GO:0019637;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;glycerolipid metabolic process#GO:0046486;metabolic process#GO:0008152;negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663;cellular process#GO:0009987;regulation of mononuclear cell proliferation#GO:0032944;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;regulation of T cell activation#GO:0050863;negative regulation of cell-cell adhesion#GO:0022408;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000013842.3|UniProtKB=G3RDA7 G3RDA7 NAB1 PTHR12623:SF9 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 GORGO|Ensembl=ENSGGOG00000028299.2|UniProtKB=G3S4J5 G3S4J5 GALNT7 PTHR11675:SF68 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 7 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000015939.3|UniProtKB=G3RIN7 G3RIN7 SPATA9 PTHR35669:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 9 SPERMATOGENESIS-ASSOCIATED PROTEIN 9 GORGO|Ensembl=ENSGGOG00000010507.3|UniProtKB=G3R4P2 G3R4P2 SEC61A1 PTHR10906:SF19 SECY/SEC61-ALPHA FAMILY MEMBER PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1 binding#GO:0005488;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ribonucleoprotein complex binding#GO:0043021;transmembrane protein transporter activity#GO:0008320;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum#GO:0005791;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000042005.1|UniProtKB=A0A2I2ZBV0 A0A2I2ZBV0 PTHR23266:SF406 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-74 binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000038864.1|UniProtKB=A0A2I2ZDM4 A0A2I2ZDM4 PTHR47901:SF3 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 CASPASE-1 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of response to stress#GO:0080134;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;gene expression#GO:0010467;protein maturation#GO:0051604;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;biosynthetic process#GO:0009058;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein metabolic process#GO:0019538;proteolysis#GO:0006508;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789 canonical inflammasome complex#GO:0061702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000039854.1|UniProtKB=A0A2I2ZW86 A0A2I2ZW86 LOC101144080 PTHR22957:SF571 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000012249.3|UniProtKB=G3R971 G3R971 C4BPB PTHR45656:SF14 PROTEIN CBR-CLEC-78 C4B-BINDING PROTEIN BETA CHAIN anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;multicellular organismal reproductive process#GO:0048609;animal gross anatomical part developmental process#GO:0160108;animal organ morphogenesis#GO:0009887;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;multi-multicellular organism process#GO:0044706;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;animal organ development#GO:0048513;multicellular organism development#GO:0007275;morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelium development#GO:0060429;tube development#GO:0035295;morphogenesis of a branching structure#GO:0001763 GORGO|Ensembl=ENSGGOG00000005808.3|UniProtKB=G3QSQ3 G3QSQ3 EGF PTHR46513:SF5 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED PRO-EPIDERMAL GROWTH FACTOR molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of cell population proliferation#GO:0008284;positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGF#P00549;Gonadotropin-releasing hormone receptor pathway#P06664>EGF#P06745 GORGO|Ensembl=ENSGGOG00000008106.3|UniProtKB=G3QYI7 G3QYI7 KIF3C PTHR24115:SF734 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3C protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 plasma membrane bounded cell projection organization#GO:0120036;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000001620.3|UniProtKB=G3QGY0 G3QGY0 SLFN12 PTHR12155:SF2 SCHLAFEN RIBONUCLEASE SLFN12 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000012926.3|UniProtKB=A0A2I2Y6S8 A0A2I2Y6S8 EMSY PTHR16500:SF3 BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000003320.3|UniProtKB=G3QLB7 G3QLB7 LRRC1 PTHR48051:SF10 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000023285.2|UniProtKB=A0A2I2YZ92 A0A2I2YZ92 ODAPH PTHR40376:SF1 ODONTOGENESIS ASSOCIATED PHOSPHOPROTEIN ODONTOGENESIS ASSOCIATED PHOSPHOPROTEIN positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of developmental process#GO:0051094;regulation of multicellular organismal development#GO:2000026;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239 GORGO|Ensembl=ENSGGOG00000042109.1|UniProtKB=A0A2I2YN52 A0A2I2YN52 SOWAHC PTHR14491:SF4 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHC GORGO|Ensembl=ENSGGOG00000001725.3|UniProtKB=G3QH73 G3QH73 LRRC17 PTHR24369:SF223 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING 17 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000016129.3|UniProtKB=G3RJ55 G3RJ55 CALR PTHR11073:SF16 CALRETICULIN AND CALNEXIN CALRETICULIN calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein folding#GO:0006457;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to chemical#GO:0042221;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000005266.3|UniProtKB=A0A2I2YRH5 A0A2I2YRH5 SYT3 PTHR10024:SF176 SYNAPTOTAGMIN SYNAPTOTAGMIN-3 phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;transport#GO:0006810;positive regulation of vesicle fusion#GO:0031340;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;positive regulation of cellular component organization#GO:0051130;trans-synaptic signaling#GO:0099537;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;positive regulation of organelle organization#GO:0010638 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 GORGO|Ensembl=ENSGGOG00000009822.3|UniProtKB=A0A2I2YSR5 A0A2I2YSR5 KIDINS220 PTHR24116:SF0 KINASE D-INTERACTING SUBSTRATE OF 220 KDA KINASE D-INTERACTING SUBSTRATE OF 220 KDA molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 cell communication#GO:0007154;cellular response to nerve growth factor stimulus#GO:1990090;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000022347.2|UniProtKB=A0A2I2Z732 A0A2I2Z732 TIMP1 PTHR11844:SF20 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 1 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to hormone#GO:0009725;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of protein catabolic process#GO:0042177;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of catabolic process#GO:0009894;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of catabolic process#GO:0009895;response to peptide#GO:1901652;regulation of protein catabolic process#GO:0042176 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000006543.3|UniProtKB=G3QUJ8 G3QUJ8 IL23R PTHR23036:SF112 CYTOKINE RECEPTOR INTERLEUKIN-23 RECEPTOR transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375 cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716 signaling receptor complex#GO:0043235;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016632.3|UniProtKB=G3RKG3 G3RKG3 SLC17A7 PTHR11662:SF29 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 1 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310 neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;localization#GO:0051179;cell communication#GO:0007154;cellular localization#GO:0051641;regulation of synapse structure or activity#GO:0050803;trans-synaptic signaling#GO:0099537 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202 secondary carrier transporter#PC00258 Metabotropic glutamate receptor group III pathway#P00039>Vglut#P01038 GORGO|Ensembl=ENSGGOG00000000976.3|UniProtKB=A0A2I2YS26 A0A2I2YS26 SERPINE2 PTHR11461:SF48 SERINE PROTEASE INHIBITOR, SERPIN GLIA-DERIVED NEXIN enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of proteolysis#GO:0030162;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000006554.3|UniProtKB=G3QUK6 G3QUK6 C10H12orf42 PTHR40708:SF1 RIKEN CDNA 1700113H08 GENE RIKEN CDNA 1700113H08 GENE GORGO|Ensembl=ENSGGOG00000007454.3|UniProtKB=G3QWW9 G3QWW9 CCDC182 PTHR37364:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 182 COILED-COIL DOMAIN-CONTAINING PROTEIN 182 GORGO|Ensembl=ENSGGOG00000003456.3|UniProtKB=A0A2I2ZMT8 A0A2I2ZMT8 HNRNPLL PTHR15592:SF13 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L-LIKE RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000026919.2|UniProtKB=A0A2I2ZIT9 A0A2I2ZIT9 EIF3C PTHR13937:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 eukaryotic translation initiation factor 3 complex#GO:0005852;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000008214.3|UniProtKB=G3QYT8 G3QYT8 RCCD1 PTHR46849:SF1 RCC1 DOMAIN-CONTAINING PROTEIN 1 RCC1 DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000003531.3|UniProtKB=G3QLV6 G3QLV6 MTMR14 PTHR13524:SF2 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR14 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000002880.3|UniProtKB=G3QK69 G3QK69 NPHP1 PTHR15176:SF1 NEPHROCYSTIN NEPHROCYSTIN-1 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;localization#GO:0051179;non-motile cilium assembly#GO:1905515;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ciliary base#GO:0097546;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;ciliary transition zone#GO:0035869 cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000013334.3|UniProtKB=A0A2I2Z9P7 A0A2I2Z9P7 PTGR1 PTHR43205:SF33 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 unsaturated fatty acid metabolic process#GO:0033559;prostaglandin metabolic process#GO:0006693;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;long-chain fatty acid metabolic process#GO:0001676;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000038484.1|UniProtKB=A0A2I2Y7G9 A0A2I2Y7G9 PTHR12638:SF1 PROTEIN MAGO NASHI HOMOLOG PROTEIN MAGO NASHI HOMOLOG 2 RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA splicing#GO:0008380;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;nuclear mRNA surveillance#GO:0071028;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 GORGO|Ensembl=ENSGGOG00000000276.3|UniProtKB=A0A2I2ZT72 A0A2I2ZT72 MYO1D PTHR13140:SF417 MYOSIN UNCONVENTIONAL MYOSIN-ID isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;transport#GO:0006810;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based movement#GO:0030048 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000007579.3|UniProtKB=G3QX82 G3QX82 CD81 PTHR19282:SF214 TETRASPANIN CD81 ANTIGEN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012224.3|UniProtKB=G3R983 G3R983 CHD7 PTHR45623:SF20 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD7 ATP hydrolysis activity#GO:0016887;DNA binding#GO:0003677;hydrolase activity#GO:0016787;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817 biological regulation#GO:0065007;chromatin organization#GO:0006325;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;inner ear development#GO:0048839;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heart morphogenesis#GO:0003007;system development#GO:0048731;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;embryo development#GO:0009790;nervous system development#GO:0007399;heart development#GO:0007507;cellular process#GO:0009987;inner ear morphogenesis#GO:0042472;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;sensory organ morphogenesis#GO:0090596;central nervous system development#GO:0007417;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;ear development#GO:0043583;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004401.3|UniProtKB=G3SG69 G3SG69 GRHL2 PTHR11037:SF17 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 2 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epithelium development#GO:0060429;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;head development#GO:0060322;tube development#GO:0035295;nervous system development#GO:0007399 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000022239.2|UniProtKB=G3RZS8 G3RZS8 RIPPLY2 PTHR16770:SF3 PROTEIN RIPPLY-LIKE PROTEIN RIPPLY2 developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;embryonic pattern specification#GO:0009880;embryo development#GO:0009790;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000028510.2|UniProtKB=G3RZ66 G3RZ66 PTHR13968:SF28 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RRM DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000024689.2|UniProtKB=G3S127 G3S127 LOC101138086 PTHR40712:SF2 FAMILY WITH SEQUENCE SIMILARITY 153 MEMBER C-RELATED FAMILY WITH SEQUENCE SIMILARITY 153 MEMBER C, PSEUDOGENE-RELATED GORGO|Ensembl=ENSGGOG00000001862.3|UniProtKB=G3QHK6 G3QHK6 DHX29 PTHR18934:SF264 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX29 isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005228.3|UniProtKB=G3QR80 G3QR80 OR1Q1 PTHR26452:SF292 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5G3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004228.3|UniProtKB=G3QNN9 G3QNN9 CTNNAL1 PTHR46342:SF1 ALPHA-CATULIN ALPHA-CATULIN Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264 Wnt signaling pathway#P00057>alpha-catenin#P01471 GORGO|Ensembl=ENSGGOG00000014156.3|UniProtKB=G3RE41 G3RE41 ADAM19 PTHR11905:SF19 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 19 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;membrane protein ectodomain proteolysis#GO:0006509;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000011202.3|UniProtKB=G3R6H0 G3R6H0 CFAP90 PTHR34444:SF1 LOC361192 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 90 GORGO|Ensembl=ENSGGOG00000011012.3|UniProtKB=G3R617 G3R617 ABHD18 PTHR13617:SF14 PROTEIN ABHD18 CARDIOLIPIN-SPECIFIC DEACYLASE, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;lipase activity#GO:0016298;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity#GO:0016787 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylglycerol metabolic process#GO:0046471;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000015608.3|UniProtKB=G3RHV1 G3RHV1 GAS2L2 PTHR46756:SF14 TRANSGELIN GAS2-LIKE PROTEIN 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of microtubule-based process#GO:0032886;actin filament-based process#GO:0030029;microtubule bundle formation#GO:0001578;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;protein localization to organelle#GO:0033365;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;intracellular protein localization#GO:0008104;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;protein localization to microtubule cytoskeleton#GO:0072698;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987 microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;actomyosin#GO:0042641;microtubule cytoskeleton#GO:0015630;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule end#GO:1990752;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000000383.3|UniProtKB=G3QDQ3 G3QDQ3 SPDEF PTHR11849:SF182 ETS SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000043838.1|UniProtKB=G3RN70 G3RN70 USP51 PTHR24006:SF665 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000008196.3|UniProtKB=G3RU39 G3RU39 SESN1 PTHR12474:SF3 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-1 organic acid binding#GO:0043177;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;cation binding#GO:0043169;catalytic activity#GO:0003824;amino acid binding#GO:0016597;oxidoreductase activity#GO:0016491 response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;positive regulation of catabolic process#GO:0009896;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;response to nitrogen compound#GO:1901698;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;response to acid chemical#GO:0001101;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to chemical#GO:0042221;cellular response to amino acid starvation#GO:0034198;negative regulation of signal transduction#GO:0009968;negative regulation of TORC1 signaling#GO:1904262;regulation of macroautophagy#GO:0016241;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;positive regulation of macroautophagy#GO:0016239;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 oxidoreductase#PC00176;peroxidase#PC00180 GORGO|Ensembl=ENSGGOG00000014673.3|UniProtKB=G3SEY3 G3SEY3 KRT8 PTHR45616:SF26 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 8 actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003981.3|UniProtKB=A0A2I2YEE5 A0A2I2YEE5 IFIT5 PTHR10271:SF28 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to virus#GO:0009615;response to peptide#GO:1901652;immune system process#GO:0002376;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to virus#GO:0051607;antiviral innate immune response#GO:0140374;cellular response to cytokine stimulus#GO:0071345 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000166.3|UniProtKB=G3QD56 G3QD56 BTF3 PTHR10351:SF28 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008645.3|UniProtKB=A0A2I2YF03 A0A2I2YF03 SCAF8 PTHR15921:SF7 PRE-MRNA CLEAVAGE COMPLEX II SR-RELATED AND CTD-ASSOCIATED FACTOR 8 RNA polymerase core enzyme binding#GO:0043175;RNA polymerase binding#GO:0070063;protein binding#GO:0005515;RNA binding#GO:0003723;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription termination#GO:0006353;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008073.3|UniProtKB=G3QYG5 G3QYG5 LTF PTHR11485:SF55 TRANSFERRIN LACTOTRANSFERRIN defense response to bacterium#GO:0042742;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;immune system process#GO:0002376;response to bacterium#GO:0009617;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;response to external biotic stimulus#GO:0043207;metal ion transport#GO:0030001;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;transport#GO:0006810;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to external stimulus#GO:0009605;defense response#GO:0006952;antibacterial humoral response#GO:0019731;establishment of localization#GO:0051234;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;defense response to other organism#GO:0098542 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;extracellular region#GO:0005576;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000000279.3|UniProtKB=G3QDF8 G3QDF8 LGALS12 PTHR11346:SF111 GALECTIN GALECTIN-12 binding#GO:0005488;oligosaccharide binding#GO:0070492;carbohydrate binding#GO:0030246 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000040256.1|UniProtKB=A0A2I2ZMR2 A0A2I2ZMR2 PTHR15591:SF16 RUN AND SH3 DOMAIN CONTAINING FARNESYL PYROPHOSPHATE SYNTHASE intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000006946.3|UniProtKB=G3QVL9 G3QVL9 SPAM1 PTHR11769:SF20 HYALURONIDASE HYALURONIDASE PH-20 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;glycosaminoglycan catabolic process#GO:0006027;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000008913.3|UniProtKB=G3R0M5 G3R0M5 AADACL2 PTHR23024:SF223 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE-LIKE 2 cellular anatomical structure#GO:0110165;membrane#GO:0016020 deacetylase#PC00087 GORGO|Ensembl=ENSGGOG00000024672.2|UniProtKB=G3RVU2 G3RVU2 CAVIN1 PTHR15240:SF3 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription initiation at RNA polymerase I promoter#GO:0006361;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription termination#GO:0006353;transcription by RNA polymerase I#GO:0006360 cell periphery#GO:0071944;caveola#GO:0005901;membrane#GO:0016020;membrane raft#GO:0045121;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;membrane microdomain#GO:0098857;intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853 membrane traffic protein#PC00150 General transcription by RNA polymerase I#P00022>PTRF#P00656 GORGO|Ensembl=ENSGGOG00000000937.3|UniProtKB=G3QF59 G3QF59 METTL4 PTHR12829:SF9 N6-ADENOSINE-METHYLTRANSFERASE N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on DNA#GO:0140097;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000006716.3|UniProtKB=G3RX52 G3RX52 OSR2 PTHR14196:SF4 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;renal system development#GO:0072001;kidney development#GO:0001822;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000025660.2|UniProtKB=G3RM05 G3RM05 ZNF598 PTHR22938:SF0 ZINC FINGER PROTEIN 598 E3 UBIQUITIN-PROTEIN LIGASE ZNF598 ubiquitin-protein transferase activity#GO:0004842;protein-containing complex binding#GO:0044877;ubiquitin-like protein ligase activity#GO:0061659;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;rescue of stalled cytosolic ribosome#GO:0072344;protein modification by small protein conjugation#GO:0032446;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein modification by small protein conjugation or removal#GO:0070647;translation#GO:0006412;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;macromolecule modification#GO:0043412;organelle disassembly#GO:1903008;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;post-translational protein modification#GO:0043687;biosynthetic process#GO:0009058;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;translational elongation#GO:0006414;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000042560.1|UniProtKB=A0A2I2Z323 A0A2I2Z323 PTHR23267:SF437 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 2-8 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000009394.4|UniProtKB=A0A2I2Y548 A0A2I2Y548 CNTNAP4 PTHR15036:SF40 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 4 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;developmental process#GO:0032502;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000012168.3|UniProtKB=G3R8Z2 G3R8Z2 MSGN1 PTHR20937:SF4 IP14615P MESOGENIN-1 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biosynthetic process#GO:0009889;mesoderm development#GO:0007498;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;developmental process#GO:0032502;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;mesoderm formation#GO:0001707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;tissue morphogenesis#GO:0048729;formation of primary germ layer#GO:0001704;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;mesoderm morphogenesis#GO:0048332;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;gastrulation#GO:0007369 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000026331.2|UniProtKB=G3S2H7 G3S2H7 BCAN PTHR22804:SF41 AGGRECAN/VERSICAN PROTEOGLYCAN BREVICAN CORE PROTEIN central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell periphery#GO:0071944;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;membrane#GO:0016020;cell junction#GO:0030054;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000026556.2|UniProtKB=G3RNP2 G3RNP2 PTHR11071:SF532 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000022943.2|UniProtKB=G3SBW9 G3SBW9 DHX16 PTHR18934:SF83 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16 helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000042316.1|UniProtKB=A0A2I2ZN33 A0A2I2ZN33 VSIG10L2 PTHR11640:SF171 NEPHRIN V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE 2 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000037022.1|UniProtKB=G3S622 G3S622 LOC101144435 PTHR20981:SF8 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016313.3|UniProtKB=G3RJL6 G3RJL6 MED21 PTHR13381:SF1 RNA POLYMERASE II HOLOENZYME COMPONENT SRB7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000043329.1|UniProtKB=A0A2I2YI90 A0A2I2YI90 PNMA2 PTHR23095:SF16 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN MA2 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000006079.3|UniProtKB=G3SJT4 G3SJT4 LRP3 PTHR24270:SF22 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 3 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;apolipoprotein#PC00052 Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP#P00150 GORGO|Ensembl=ENSGGOG00000013441.3|UniProtKB=G3RY65 G3RY65 AKAP8L PTHR12190:SF4 A-KINASE ANCHOR PROTEIN AKAP 8 A-KINASE ANCHOR PROTEIN 8-LIKE protein kinase A regulatory subunit binding#GO:0034237;binding#GO:0005488;protein kinase A binding#GO:0051018;protein binding#GO:0005515 cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;nuclear division#GO:0000280 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007769.3|UniProtKB=G3QXP7 G3QXP7 LDLRAP1 PTHR11232:SF35 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER LOW DENSITY LIPOPROTEIN RECEPTOR ADAPTER PROTEIN 1 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;regulation of biological process#GO:0050789;receptor internalization#GO:0031623;biological regulation#GO:0065007;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;plasma lipoprotein particle clearance#GO:0034381;localization#GO:0051179 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003404.3|UniProtKB=G3QLJ8 G3QLJ8 ABCC3 PTHR24223:SF405 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 3 transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;xenobiotic transmembrane transporter activity#GO:0042910;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000008128.3|UniProtKB=G3QYM2 G3QYM2 REV3L PTHR45812:SF1 DNA POLYMERASE ZETA CATALYTIC SUBUNIT DNA POLYMERASE ZETA CATALYTIC SUBUNIT DNA-directed DNA polymerase activity#GO:0003887;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA synthesis involved in DNA replication#GO:0090592;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;translesion synthesis#GO:0019985;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 GORGO|Ensembl=ENSGGOG00000027553.2|UniProtKB=G3S2C8 G3S2C8 MYOC PTHR23192:SF33 OLFACTOMEDIN-RELATED MYOCILIN multicellular organismal process#GO:0032501;ossification#GO:0001503;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular developmental process#GO:0048869;cell communication#GO:0007154;osteoblast differentiation#GO:0001649;developmental process#GO:0032502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000042260.1|UniProtKB=A0A2I2Z257 A0A2I2Z257 EML5 PTHR13720:SF16 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 5 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000003488.3|UniProtKB=A0A2I2ZLS2 A0A2I2ZLS2 TENM1 PTHR11219:SF7 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 synapse organization#GO:0050808;anatomical structure development#GO:0048856;system development#GO:0048731;cell junction organization#GO:0034330;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell adhesion#GO:0007155;synaptic membrane adhesion#GO:0099560;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399 cell junction#GO:0030054;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 GORGO|Gene=PEG3|UniProtKB=A1YFC1 A1YFC1 PEG3 PTHR24381:SF293 ZINC FINGER PROTEIN PATERNALLY-EXPRESSED GENE 3 PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004419.3|UniProtKB=G3QP48 G3QP48 IL12B PTHR48485:SF4 INTERLEUKIN-12 SUBUNIT BETA-RELATED INTERLEUKIN-12 SUBUNIT BETA binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine binding#GO:0019955;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000009910.3|UniProtKB=G3R360 G3R360 HOXB2 PTHR45664:SF7 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000040448.1|UniProtKB=A0A2I2Z0J1 A0A2I2Z0J1 KRT15 PTHR23239:SF164 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 15 structural molecule activity#GO:0005198 intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;cytoskeleton organization#GO:0007010;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cellular process#GO:0009987;organelle organization#GO:0006996;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502 organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000008870.3|UniProtKB=G3S4H7 G3S4H7 CCDC38 PTHR21683:SF7 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 38 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000007605.3|UniProtKB=G3QXA4 G3QXA4 TGM7 PTHR11590:SF41 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE Z catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001977.3|UniProtKB=G3SFI7 G3SFI7 ARHGAP9 PTHR23176:SF103 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 9 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000024659.2|UniProtKB=A0A2I2ZD40 A0A2I2ZD40 PTHR16875:SF0 SELENOPROTEIN K SELENOPROTEIN K intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of response to stimulus#GO:0048583;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;inorganic ion homeostasis#GO:0098771;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;calcium ion homeostasis#GO:0055074;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 GORGO|Ensembl=ENSGGOG00000002334.3|UniProtKB=G3QIS9 G3QIS9 ATP5F1D PTHR13822:SF7 ATP SYNTHASE DELTA/EPSILON CHAIN ATP SYNTHASE F(1) COMPLEX SUBUNIT DELTA, MITOCHONDRIAL proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874 carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside triphosphate biosynthetic process#GO:0009145;organophosphate biosynthetic process#GO:0090407;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;proton-transporting ATP synthase complex#GO:0045259;respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000014962.3|UniProtKB=G3RG61 G3RG61 MRNIP PTHR15863:SF2 MRN COMPLEX-INTERACTING PROTEIN MRN COMPLEX-INTERACTING PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 mitotic cell cycle process#GO:1903047;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000006727.3|UniProtKB=G3QV21 G3QV21 VPS4B PTHR23074:SF72 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4B hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;cellular localization#GO:0051641;localization#GO:0051179;vacuole organization#GO:0007033;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;endosomal transport#GO:0016197;macromolecule catabolic process#GO:0009057;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;vesicle-mediated transport#GO:0016192;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;organelle organization#GO:0006996;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000014030.3|UniProtKB=G3RDS7 G3RDS7 ENTPD7 PTHR11782:SF37 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 7 ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside diphosphate metabolic process#GO:0009185;nucleoside diphosphate catabolic process#GO:0009134;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleoside diphosphate metabolic process#GO:0009132;ribonucleotide metabolic process#GO:0009259;ribonucleoside diphosphate catabolic process#GO:0009191;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 GORGO|Gene=PROP1|UniProtKB=Q3LU39 Q3LU39 PROP1 PTHR47409:SF1 HOMEOBOX PROTEIN PROPHET OF PIT-1 HOMEOBOX PROTEIN PROPHET OF PIT-1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000015224.3|UniProtKB=G3RGU2 G3RGU2 UBTD1 PTHR13609:SF11 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED UBIQUITIN DOMAIN-CONTAINING PROTEIN 1 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002892.3|UniProtKB=G3QK81 G3QK81 THBS2 PTHR10199:SF10 THROMBOSPONDIN THROMBOSPONDIN-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603;regulation of angiogenesis#GO:0045765;regulation of vasculature development#GO:1901342 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000000830.3|UniProtKB=A0A2I2YM68 A0A2I2YM68 CDC25C PTHR10828:SF64 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 M-PHASE INDUCER PHOSPHATASE 3 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;regulation of reproductive process#GO:2000241;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle G2/M phase transition#GO:1902749;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway#P00059>Cdc25C#P04624 GORGO|Ensembl=ENSGGOG00000007243.3|UniProtKB=G3QWD9 G3QWD9 JAK2 PTHR45807:SF1 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK2 non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096 innate immune response#GO:0045087;multicellular organismal-level homeostasis#GO:0048871;defense response#GO:0006952;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to tumor necrosis factor#GO:0034612;immune response#GO:0006955;chemokine-mediated signaling pathway#GO:0070098;anatomical structure development#GO:0048856;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;cellular response to chemokine#GO:1990869;cellular response to stimulus#GO:0051716;defense response to other organism#GO:0098542;cell surface receptor signaling pathway via STAT#GO:0097696;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;response to type II interferon#GO:0034341;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;myeloid cell differentiation#GO:0030099;cell development#GO:0048468;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;developmental process#GO:0032502;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;cellular response to nitrogen compound#GO:1901699;hemopoiesis#GO:0030097;response to other organism#GO:0051707;cell communication#GO:0007154;erythrocyte differentiation#GO:0030218;enzyme-linked receptor protein signaling pathway#GO:0007167;tumor necrosis factor-mediated signaling pathway#GO:0033209;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;homeostasis of number of cells#GO:0048872;response to external biotic stimulus#GO:0043207;homeostatic process#GO:0042592;cellular response to peptide hormone stimulus#GO:0071375;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stress#GO:0006950;response to hormone#GO:0009725;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 PDGF signaling pathway#P00047>Jak#P01155;PI3 kinase pathway#P00048>JAK#P01176;CCKR signaling map#P06959>JAK2#P07156;Interferon-gamma signaling pathway#P00035>Jak2#P00952;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>JAK#P00846;JAK/STAT signaling pathway#P00038>Jak#P01034 GORGO|Ensembl=ENSGGOG00000008990.3|UniProtKB=G3R0U6 G3R0U6 TBX22 PTHR11267:SF116 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX22 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 GORGO|Ensembl=ENSGGOG00000017088.3|UniProtKB=G3S7F6 G3S7F6 PTHR47138:SF1 PERILIPIN-1 PERILIPIN-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000040286.1|UniProtKB=G3RM71 G3RM71 LOC101141751 PTHR23430:SF245 HISTONE H2A HISTONE H2A TYPE 1 structural molecule activity#GO:0005198 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000016760.3|UniProtKB=G3RKU3 G3RKU3 VWF PTHR11339:SF361 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VON WILLEBRAND FACTOR extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;regulation of biological quality#GO:0065008;blood coagulation#GO:0007596;wound healing#GO:0042060;response to wounding#GO:0009611;hemostasis#GO:0007599;response to stress#GO:0006950;cellular process#GO:0009987;coagulation#GO:0050817;regulation of body fluid levels#GO:0050878;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;biological regulation#GO:0065007 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Blood coagulation#P00011>vWF#P00448;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863 GORGO|Ensembl=ENSGGOG00000016124.3|UniProtKB=G3RJ59 G3RJ59 VPS16 PTHR12811:SF3 VACUOLAR PROTEIN SORTING VPS16 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;vacuole fusion, non-autophagic#GO:0042144;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endosomal transport#GO:0016197;cellular component organization#GO:0016043;vacuole fusion#GO:0097576;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033 membrane#GO:0016020;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle tethering complex#GO:0099023;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000002809.3|UniProtKB=G3QK08 G3QK08 GAMT PTHR32379:SF2 GUANIDINOACETATE N-METHYLTRANSFERASE GUANIDINOACETATE N-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;monocarboxylic acid metabolic process#GO:0032787;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 methyltransferase#PC00155;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000002120.3|UniProtKB=G3QI84 G3QI84 SMPD1 PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;ceramide metabolic process#GO:0006672 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;lysosome#GO:0005764 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000041966.1|UniProtKB=A0A2I2YV92 A0A2I2YV92 TMEM262 PTHR37998:SF1 TRANSMEMBRANE PROTEIN 262 CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT ETA GORGO|Ensembl=ENSGGOG00000037874.1|UniProtKB=A0A2I2ZJ10 A0A2I2ZJ10 PHLDA3 PTHR15478:SF5 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 3 negative regulation of cell communication#GO:0010648;intrinsic apoptotic signaling pathway#GO:0097193;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;signal transduction by p53 class mediator#GO:0072331;negative regulation of signaling#GO:0023057;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell communication#GO:0007154;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;apoptotic signaling pathway#GO:0097190;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000007317.3|UniProtKB=G3QWK3 G3QWK3 SQLE PTHR10835:SF0 SQUALENE MONOOXYGENASE SQUALENE MONOOXYGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxygenase#PC00177 Cholesterol biosynthesis#P00014>Squalene monooxygenas#P00494 GORGO|Ensembl=ENSGGOG00000009988.3|UniProtKB=G3R3C7 G3R3C7 TBC1D10C PTHR22957:SF324 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN CARABIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000008928.3|UniProtKB=G3R0P0 G3R0P0 BRAT1 PTHR21331:SF2 BRCA1-ASSOCIATED ATM ACTIVATOR 1 INTEGRATOR COMPLEX ASSEMBLY FACTOR BRAT1 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000013922.3|UniProtKB=G3RDH9 G3RDH9 CCDC78 PTHR22106:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000024545.2|UniProtKB=G3S7U9 G3S7U9 PTHR26453:SF763 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005624.3|UniProtKB=G3QS80 G3QS80 RDH11 PTHR43157:SF70 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED NADP-RETINOL DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000001819.3|UniProtKB=G3RXT6 G3RXT6 SLC27A6 PTHR43107:SF10 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 6 ligase activity, forming carbon-sulfur bonds#GO:0016877;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;monocarboxylic acid transmembrane transporter activity#GO:0008028;catalytic activity#GO:0003824;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874 lipid transport#GO:0006869;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;organic acid transport#GO:0015849;lipid metabolic process#GO:0006629;transport#GO:0006810;carboxylic acid transport#GO:0046942;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000010629.3|UniProtKB=G3SD90 G3SD90 BCCIP PTHR13261:SF0 BRCA2 AND CDKN1A INTERACTING PROTEIN BRCA2 AND CDKN1A-INTERACTING PROTEIN enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;microtubule anchoring#GO:0034453;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of protein modification process#GO:0031399;mitotic cell cycle process#GO:1903047 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819 GORGO|Ensembl=ENSGGOG00000008363.3|UniProtKB=G3RWC9 G3RWC9 NXPH2 PTHR17103:SF11 NEUREXOPHILIN NEUREXOPHILIN-2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;GABA-ergic synapse#GO:0098982 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000010801.3|UniProtKB=G3R5F7 G3R5F7 SNX32 PTHR45850:SF3 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-32 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007476.3|UniProtKB=G3QX11 G3QX11 PTHR46141:SF1 SODIUM LEAK CHANNEL NON-SELECTIVE PROTEIN SODIUM LEAK CHANNEL NALCN monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of synaptic transmission#GO:0050806;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000011723.4|UniProtKB=G3R7T7 G3R7T7 ARID1B PTHR12656:SF11 BRG-1 ASSOCIATED FACTOR 250 BAF250 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1B nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000003940.3|UniProtKB=G3QMW7 G3QMW7 PRPF38A PTHR23142:SF7 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38A primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011395.3|UniProtKB=G3R6Y5 G3R6Y5 LRFN1 PTHR24369:SF172 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000011522.3|UniProtKB=G3R7A5 G3R7A5 SPSB4 PTHR12245:SF3 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007246.3|UniProtKB=G3QWD6 G3QWD6 TUBD1 PTHR11588:SF4 TUBULIN TUBULIN DELTA CHAIN ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 tubulin#PC00228;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000008583.3|UniProtKB=G3QZS6 G3QZS6 NR1H3 PTHR48092:SF2 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 1, GROUP H, MEMBER 3 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000008089.3|UniProtKB=G3QYH9 G3QYH9 KPNB1 PTHR10527:SF1 IMPORTIN BETA IMPORTIN SUBUNIT BETA-1 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000036173.1|UniProtKB=A0A2I2YX73 A0A2I2YX73 TMEM229B PTHR31746:SF3 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229B GORGO|Ensembl=ENSGGOG00000028579.2|UniProtKB=G3S6Y9 G3S6Y9 FGFBP2 PTHR15258:SF1 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 2 binding#GO:0005488;growth factor binding#GO:0019838;protein binding#GO:0005515 signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000040686.1|UniProtKB=A0A2I2YCI6 A0A2I2YCI6 PTHR11787:SF16 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000013148.3|UniProtKB=G3RBG8 G3RBG8 LINGO2 PTHR24369:SF156 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE RICH REPEAT AND IG DOMAIN CONTAINING 2 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000011905.3|UniProtKB=A0A2I2ZV52 A0A2I2ZV52 ACTN2 PTHR11915:SF429 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-2 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;muscle cell development#GO:0055001;cellular component organization#GO:0016043;muscle cell differentiation#GO:0042692;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell development#GO:0048468;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010 actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;contractile muscle fiber#GO:0043292;cell periphery#GO:0071944;Z disc#GO:0030018;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;I band#GO:0031674;cell junction#GO:0030054;sarcomere#GO:0030017;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 GORGO|Ensembl=ENSGGOG00000044112.1|UniProtKB=A0A2I2YL38 A0A2I2YL38 ANG PTHR11437:SF60 RIBONUCLEASE ANGIOGENIN catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540 defense response to Gram-positive bacterium#GO:0050830;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;biological process involved in interspecies interaction between organisms#GO:0044419;circulatory system development#GO:0072359;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;angiogenesis#GO:0001525;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;antibacterial humoral response#GO:0019731;multicellular organism development#GO:0007275;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;response to external biotic stimulus#GO:0043207;response to bacterium#GO:0009617;system development#GO:0048731;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;anatomical structure development#GO:0048856;immune response#GO:0006955;response to other organism#GO:0051707;tube development#GO:0035295;multicellular organismal process#GO:0032501;developmental process#GO:0032502;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007868.3|UniProtKB=A0A2I2ZEZ5 A0A2I2ZEZ5 PLD1 PTHR18896:SF57 PHOSPHOLIPASE D PHOSPHOLIPASE D1 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;lipase activity#GO:0016298;hydrolase activity#GO:0016787 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;organophosphate catabolic process#GO:0046434;organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of localization#GO:0032879;regulation of transport#GO:0051049 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 lipase#PC00143;phospholipase#PC00186 Angiogenesis#P00005>PLD#P00204;Ras Pathway#P04393>PLD#P04574 GORGO|Ensembl=ENSGGOG00000034840.2|UniProtKB=G3SKD9 G3SKD9 IL24 PTHR48482:SF4 INTERLEUKIN-19-RELATED INTERLEUKIN-24 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000027946.2|UniProtKB=G3SJA0 G3SJA0 MAMDC2 PTHR23282:SF116 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000041666.1|UniProtKB=G3R564 G3R564 PTHR22722:SF20 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000038878.1|UniProtKB=G3QV22 G3QV22 LOC101126289 PTHR24384:SF204 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 726 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016499.3|UniProtKB=A0A2I2ZBY0 A0A2I2ZBY0 GABRG1 PTHR18945:SF93 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-1 monoatomic ion transmembrane transporter activity#GO:0015075;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;ligand-gated channel activity#GO:0022834;neurotransmitter receptor activity#GO:0030594;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;localization#GO:0051179;chloride transmembrane transport#GO:1902476;anatomical structure development#GO:0048856;system development#GO:0048731;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;synapse assembly#GO:0007416;signaling#GO:0023052;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;animal gross anatomical part developmental process#GO:0160108;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;chloride transport#GO:0006821 cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection membrane#GO:0031253;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000011076.3|UniProtKB=G3R656 G3R656 PTHR23288:SF4 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell-cell junction organization#GO:0045216;transcription by RNA polymerase II#GO:0006366;regulation of macromolecule metabolic process#GO:0060255;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;regulation of RNA metabolic process#GO:0051252;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cell-cell junction assembly#GO:0007043;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;snRNA transcription#GO:0009301;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187 apical junction complex#GO:0043296;apical part of cell#GO:0045177;tight junction#GO:0070160;nuclear protein-containing complex#GO:0140513;cell junction#GO:0030054;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cell periphery#GO:0071944;nucleus#GO:0005634;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular vesicle#GO:0097708;apical plasma membrane#GO:0016324;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000027850.2|UniProtKB=A0A2I2Y9L5 A0A2I2Y9L5 MEIS3P2 PTHR11850:SF332 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS3-LIKE 1-RELATED DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 head development#GO:0060322;embryo development#GO:0009790;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;sensory system development#GO:0048880;embryonic pattern specification#GO:0009880;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;eye development#GO:0001654;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;pattern specification process#GO:0007389 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016898.3|UniProtKB=A0A2I2YTI8 A0A2I2YTI8 ABR PTHR23182:SF5 BREAKPOINT CLUSTER REGION PROTEIN BCR ACTIVE BREAKPOINT CLUSTER REGION-RELATED PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of signal transduction#GO:0009966;regulation of biological process#GO:0050789 cell junction#GO:0030054;postsynaptic density#GO:0014069;plasma membrane#GO:0005886;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020 G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000001356.3|UniProtKB=G3QG88 G3QG88 GLE1 PTHR12960:SF0 GLE-1-RELATED MRNA EXPORT FACTOR GLE1 phospholipid binding#GO:0005543;translation initiation factor binding#GO:0031369;alcohol binding#GO:0043178;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;protein binding#GO:0005515;lipid binding#GO:0008289 macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000014887.3|UniProtKB=A0A2I2ZD14 A0A2I2ZD14 PLEKHG1 PTHR45924:SF1 FI17866P1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 1 binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 GORGO|Ensembl=ENSGGOG00000004115.3|UniProtKB=G3QNC4 G3QNC4 ARPC5L PTHR12644:SF2 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5-LIKE PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin nucleation#GO:0045010;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Huntington disease#P00029>Arp2/3 complex#P00811 GORGO|Ensembl=ENSGGOG00000006689.3|UniProtKB=G3QUY4 G3QUY4 MUL1 PTHR12183:SF4 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein stability#GO:0031647;regulation of anatomical structure morphogenesis#GO:0022603;protein stabilization#GO:0050821;positive regulation of developmental process#GO:0051094 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000041782.1|UniProtKB=A0A2I2ZRE8 A0A2I2ZRE8 ING2 PTHR10333:SF37 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 2 histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;chromatin-protein adaptor activity#GO:0140463 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000011199.3|UniProtKB=G3R6G8 G3R6G8 ZNF502 PTHR24409:SF450 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002229.3|UniProtKB=A0A2I2Y2D9 A0A2I2Y2D9 SSX2IP PTHR46507:SF1 AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;intraciliary transport involved in cilium assembly#GO:0035735;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;cilium assembly#GO:0060271;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111 cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;centriolar satellite#GO:0034451;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000007541.3|UniProtKB=G3QX46 G3QX46 IFI27L2 PTHR16932:SF35 INTERFERON ALPHA-INDUCIBLE PROTEIN 27 INTERFERON ALPHA-INDUCIBLE PROTEIN 27-LIKE PROTEIN 2 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;programmed cell death#GO:0012501;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009280.3|UniProtKB=A0A2I2YGS0 A0A2I2YGS0 PTHR17530:SF2 PRO-THYROTROPIN-RELEASING HORMONE PRO-THYROTROPIN-RELEASING HORMONE hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 intracellular organelle#GO:0043229;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585 GORGO|Ensembl=ENSGGOG00000034816.2|UniProtKB=A0A2I2YK02 A0A2I2YK02 PTHR19302:SF70 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 6 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 sexual reproduction#GO:0019953;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cytoplasmic microtubule organization#GO:0031122;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000001369.4|UniProtKB=G3QGA1 G3QGA1 TMOD1 PTHR10901:SF8 TROPOMODULIN TROPOMODULIN-1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;system process#GO:0003008;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;muscle contraction#GO:0006936;developmental process#GO:0032502;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000024929.2|UniProtKB=G3RXR2 G3RXR2 PTHR46232:SF3 SMARCE1 REGULATOR OF CHROMATIN SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1 nuclear receptor binding#GO:0016922;binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000630.3|UniProtKB=G3SDJ0 G3SDJ0 PTHR23267:SF133 IMMUNOGLOBULIN LIGHT CHAIN PRE-B LYMPHOCYTE PROTEIN 3 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000012847.3|UniProtKB=G3S853 G3S853 PBXIP1 PTHR28638:SF1 CELL CYCLE PROGRESSION PROTEIN 1 PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR-INTERACTING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000005057.3|UniProtKB=G3QQT0 G3QQT0 GXYLT2 PTHR46012:SF1 IP22168P GLUCOSIDE XYLOSYLTRANSFERASE 2 pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;transferase activity#GO:0016740;catalytic activity#GO:0003824;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000037710.1|UniProtKB=A0A2I2Z7K3 A0A2I2Z7K3 LOC109028648 PTHR26451:SF146 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000009370.3|UniProtKB=G3R1S3 G3R1S3 ERP27 PTHR18929:SF193 PROTEIN DISULFIDE ISOMERASE ENDOPLASMIC RETICULUM RESIDENT PROTEIN 27 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 response to stimulus#GO:0050896;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000043721.1|UniProtKB=A0A2I2ZEU2 A0A2I2ZEU2 LOC101123985 PTHR11726:SF36 60S RIBOSOMAL PROTEIN L10 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003649.3|UniProtKB=G3QM72 G3QM72 CACNA1D PTHR45628:SF11 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1D calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803 calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509 calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 GORGO|Ensembl=ENSGGOG00000042693.1|UniProtKB=A0A2I2ZTD5 A0A2I2ZTD5 PTHR23267:SF360 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 5-52 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000011256.3|UniProtKB=G3SDE0 G3SDE0 SPAG8 PTHR15510:SF5 SPERM-ASSOCIATED ANTIGEN 8 SPERM-ASSOCIATED ANTIGEN 8 cilium movement involved in cell motility#GO:0060294;sperm motility#GO:0097722;cellular process#GO:0009987;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017 cytoplasmic microtubule#GO:0005881;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000002004.3|UniProtKB=G3QHY4 G3QHY4 LOC101146552 PTHR14224:SF112 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 11-RELATED enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003313.3|UniProtKB=G3SKB5 G3SKB5 RECK PTHR13487:SF3 SERINE PROTEASE INHIBITOR REVERSION-INDUCING CYSTEINE-RICH PROTEIN WITH KAZAL MOTIFS enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;tube development#GO:0035295;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;system development#GO:0048731;anatomical structure maturation#GO:0071695;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;regulation of signaling#GO:0023051;angiogenesis#GO:0001525;blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;circulatory system development#GO:0072359;regulation of Wnt signaling pathway#GO:0030111 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000024919.2|UniProtKB=G3SFX1 G3SFX1 PTHR45618:SF32 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 14 monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;chloride transmembrane transporter activity#GO:0015108 regulation of response to stress#GO:0080134;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular response to stress#GO:0080135 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000025297.2|UniProtKB=G3RCV5 G3RCV5 LEKR1 PTHR34251:SF1 LEUCINE-, GLUTAMATE- AND LYSINE-RICH PROTEIN 1 LEUCINE, GLUTAMATE AND LYSINE RICH 1 GORGO|Ensembl=ENSGGOG00000003899.3|UniProtKB=G3SHX9 G3SHX9 VCPIP1 PTHR14843:SF2 DEUBIQUITINATING PROTEIN VCIP135 DEUBIQUITINATING PROTEIN VCPIP1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234 Golgi organization#GO:0007030;cellular response to stimulus#GO:0051716;endoplasmic reticulum organization#GO:0007029;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;membrane organization#GO:0061024;nucleobase-containing compound metabolic process#GO:0006139;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;DNA damage response#GO:0006974;endoplasmic reticulum membrane organization#GO:0090158;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000028117.2|UniProtKB=G3S4A6 G3S4A6 SLC13A2 PTHR10283:SF139 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007287.3|UniProtKB=A0A2I2Y4Q3 A0A2I2Y4Q3 CCKBR PTHR24241:SF131 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GASTRIN_CHOLECYSTOKININ TYPE B RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001384.3|UniProtKB=G3QGB5 G3QGB5 LRTM1 PTHR24366:SF35 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000008162.3|UniProtKB=G3QYP4 G3QYP4 FURIN PTHR42884:SF1 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;proteolysis#GO:0006508;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;protein maturation#GO:0051604;gene expression#GO:0010467;peptide hormone processing#GO:0016486;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Endothelin signaling pathway#P00019>furin#P00575 GORGO|Ensembl=ENSGGOG00000013542.3|UniProtKB=A0A2I2YV44 A0A2I2YV44 SLC31A2 PTHR12483:SF8 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS PROTEIN SLC31A2 metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;transporter regulator activity#GO:0141108;transition metal ion transmembrane transporter activity#GO:0046915 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;copper ion transmembrane transport#GO:0035434;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;transport#GO:0006810;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003796.2|UniProtKB=G3QMI7 G3QMI7 LOC101132438 PTHR12980:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX, SUBUNIT X CYTOCHROME B-C1 COMPLEX SUBUNIT 9 electron transport chain#GO:0022900;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex III#GO:0045275;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000012816.3|UniProtKB=G3RAM4 G3RAM4 EPYC PTHR46269:SF3 EPIPHYCAN-RELATED EPIPHYCAN tissue development#GO:0009888;multicellular organismal process#GO:0032501;bone development#GO:0060348;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;cartilage development#GO:0051216;connective tissue development#GO:0061448;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000039174.1|UniProtKB=A0A2I2ZWH9 A0A2I2ZWH9 SELENBP1 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000004607.3|UniProtKB=G3QPM0 G3QPM0 LOC101128530 PTHR26453:SF148 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000022670.2|UniProtKB=A0A2I2YXH4 A0A2I2YXH4 PTHR16523:SF7 PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000038053.1|UniProtKB=A0A2I2YLC3 A0A2I2YLC3 LIN7A PTHR14063:SF4 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of developmental process#GO:0050793;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of growth#GO:0040008;regulation of synapse structure or activity#GO:0050803;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of cell junction assembly#GO:1901888;regulation of synapse assembly#GO:0051963;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;vesicle localization#GO:0051648;establishment of localization#GO:0051234;transport#GO:0006810;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;export from cell#GO:0140352;regulation of biological process#GO:0050789;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;secretion by cell#GO:0032940;regulation of synapse organization#GO:0050807;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;basal part of cell#GO:0045178;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;cell-cell junction#GO:0005911;membrane#GO:0016020;adherens junction#GO:0005912;cell junction#GO:0030054 cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000021978.2|UniProtKB=G3RM11 G3RM11 TNFSF13B PTHR15151:SF2 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 positive regulation of leukocyte activation#GO:0002696;regulation of B cell proliferation#GO:0030888;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of B cell activation#GO:0050864;lymphocyte homeostasis#GO:0002260;regulation of mononuclear cell proliferation#GO:0032944;regulation of multicellular organismal process#GO:0051239;immune system process#GO:0002376;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;response to stimulus#GO:0050896;positive regulation of leukocyte proliferation#GO:0070665;multicellular organismal-level homeostasis#GO:0048871;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;multicellular organismal process#GO:0032501;regulation of lymphocyte proliferation#GO:0050670;positive regulation of lymphocyte proliferation#GO:0050671;homeostasis of number of cells#GO:0048872;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;homeostatic process#GO:0042592;positive regulation of B cell proliferation#GO:0030890;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000007555.3|UniProtKB=G3QX56 G3QX56 MED18 PTHR13321:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004028.3|UniProtKB=G3QN48 G3QN48 TCTN1 PTHR14611:SF1 TECTONIC FAMILY MEMBER TECTONIC-1 plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365 membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000015922.3|UniProtKB=G3RIN0 G3RIN0 PTHR10048:SF15 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE ALPHA catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000011555.3|UniProtKB=G3R7D5 G3R7D5 SRP9 PTHR12834:SF12 SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987 cytoplasm#GO:0005737;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000000744.3|UniProtKB=G3QEN5 G3QEN5 HAUS3 PTHR19378:SF7 GOLGIN- RELATED HAUS AUGMIN-LIKE COMPLEX SUBUNIT 3 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226 mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226;HAUS complex#GO:0070652;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819 GORGO|Gene=TAP1|UniProtKB=Q28433 Q28433 TAP1 PTHR24221:SF249 ATP-BINDING CASSETTE SUB-FAMILY B ANTIGEN PEPTIDE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;binding#GO:0005488;protein binding#GO:0005515 establishment of localization#GO:0051234;antigen processing and presentation#GO:0019882;transmembrane transport#GO:0055085;localization#GO:0051179;immune system process#GO:0002376;cellular process#GO:0009987;transport#GO:0006810 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000039753.1|UniProtKB=A0A2I2ZRP1 A0A2I2ZRP1 RNF144A PTHR11685:SF99 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144A transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Golgi apparatus#GO:0005794 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000006339.3|UniProtKB=G3QU11 G3QU11 NUCB1 PTHR19237:SF21 NUCLEOBINDIN NUCLEOBINDIN-1 metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000011164.3|UniProtKB=G3R6E2 G3R6E2 ENPP1 PTHR10151:SF77 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 1 phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 regulation of bone mineralization#GO:0030500;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;establishment of localization#GO:0051234;regulation of cell differentiation#GO:0045595;transport#GO:0006810;negative regulation of cellular process#GO:0048523;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of multicellular organismal process#GO:0051239;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;inorganic anion transport#GO:0015698;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259 plasma membrane#GO:0005886;cell surface#GO:0009986;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000016552.3|UniProtKB=G3RPY6 G3RPY6 GALC PTHR15172:SF1 GALACTOCEREBROSIDASE GALACTOCEREBROSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;carbohydrate derivative catabolic process#GO:1901136;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;ceramide metabolic process#GO:0006672 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;galactosidase#PC00104 GORGO|Ensembl=ENSGGOG00000003432.3|UniProtKB=G3QLL7 G3QLL7 HGF PTHR24261:SF8 PLASMINOGEN-RELATED HEPATOCYTE GROWTH FACTOR hydrolase activity#GO:0016787;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002289.3|UniProtKB=G3QIN7 G3QIN7 NOL4L PTHR12449:SF19 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4-LIKE GORGO|Ensembl=ENSGGOG00000027622.2|UniProtKB=G3S632 G3S632 RNH1 PTHR24112:SF50 LEUCINE-RICH REPEAT, ISOFORM F-RELATED RIBONUCLEASE INHIBITOR molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 regulation of anatomical structure morphogenesis#GO:0022603;regulation of vasculature development#GO:1901342;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;regulation of multicellular organismal process#GO:0051239;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cell migration#GO:0016477;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of angiogenesis#GO:0045765;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of multicellular organismal development#GO:2000026;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;cell periphery#GO:0071944;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cell leading edge#GO:0031252;extracellular protein-containing complex#GO:0140392;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000006696.3|UniProtKB=G3QUZ2 G3QUZ2 COQ3 PTHR43464:SF104 METHYLTRANSFERASE UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL O-methyltransferase activity#GO:0008171;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741 cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 methyltransferase#PC00155;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004968.3|UniProtKB=G3QQJ9 G3QQJ9 REG1A PTHR22803:SF131 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED LITHOSTATHINE-1-ALPHA hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545 response to external stimulus#GO:0009605;defense response#GO:0006952;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;biological regulation#GO:0065007;response to other organism#GO:0051707;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;response to stress#GO:0006950;response to nitrogen compound#GO:1901698;regulation of cell population proliferation#GO:0042127;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 CCKR signaling map#P06959>REG1A#G07269;CCKR signaling map#P06959>REG1A#G06976 GORGO|Ensembl=ENSGGOG00000028428.2|UniProtKB=A0A2I2YC78 A0A2I2YC78 PTHR13523:SF3 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 2-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;mitochondrion organization#GO:0007005;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000038833.1|UniProtKB=A0A2I2YAY2 A0A2I2YAY2 PTHR12621:SF10 CYSTEINE AND HISTIDINE-RICH DOMAIN CHORD -CONTAINING PROTEIN CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;ion binding#GO:0043167;transition metal ion binding#GO:0046914 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;centrosome cycle#GO:0007098;cytoskeleton organization#GO:0007010 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015062.3|UniProtKB=G3RGF1 G3RGF1 GNGT1 PTHR13809:SF26 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT GAMMA-T1 GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 catalytic complex#GO:1902494;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;extrinsic component of membrane#GO:0019898;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 heterotrimeric G-protein#PC00117 PI3 kinase pathway#P00048>Gbetagamma#P01188;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751 GORGO|Ensembl=ENSGGOG00000001771.3|UniProtKB=G3RU11 G3RU11 AP3B1 PTHR11134:SF10 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;lytic vacuole organization#GO:0080171;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;anterograde synaptic vesicle transport#GO:0048490;microtubule-based movement#GO:0007018;axonal transport#GO:0098930;organelle localization#GO:0051640;pigmentation#GO:0043473;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;vacuole organization#GO:0007033;anterograde axonal transport#GO:0008089;organelle organization#GO:0006996;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;cellular pigmentation#GO:0033059;melanosome organization#GO:0032438;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;vesicle organization#GO:0016050;cellular component organization#GO:0016043;establishment of organelle localization#GO:0051656;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011637.3|UniProtKB=G3R7K9 G3R7K9 SHOX2 PTHR46255:SF1 SHORT STATURE HOMEOBOX SHORT STATURE HOMEOBOX PROTEIN 2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000040887.1|UniProtKB=A0A2I2YVH9 A0A2I2YVH9 PTHR18934:SF119 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE A RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543 intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000011504.3|UniProtKB=G3SB83 G3SB83 ATF7IP PTHR23210:SF22 ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000023416.2|UniProtKB=A0A2I2ZCM4 A0A2I2ZCM4 PURG PTHR12611:SF3 PUR-TRANSCRIPTIONAL ACTIVATOR PURINE-RICH ELEMENT-BINDING PROTEIN GAMMA transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000017086.3|UniProtKB=G3RLM2 G3RLM2 KATNIP PTHR21534:SF0 KATANIN-INTERACTING PROTEIN KATANIN-INTERACTING PROTEIN GORGO|Ensembl=ENSGGOG00000042599.1|UniProtKB=A0A2I2YYK9 A0A2I2YYK9 PTHR11588:SF328 TUBULIN TUBULIN_FTSZ 2-LAYER SANDWICH DOMAIN-CONTAINING PROTEIN purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 tubulin#PC00228;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000012885.3|UniProtKB=A0A2I2YNX1 A0A2I2YNX1 EDN3 PTHR13874:SF11 ENDOTHELIN ENDOTHELIN-3 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;regulation of blood pressure#GO:0008217;monoatomic ion homeostasis#GO:0050801;regulation of systemic arterial blood pressure#GO:0003073;system process#GO:0003008;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;regulation of smooth muscle contraction#GO:0006940;muscle contraction#GO:0006936;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;homeostatic process#GO:0042592;muscle system process#GO:0003012;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;intracellular monoatomic ion homeostasis#GO:0006873;regulation of muscle system process#GO:0090257;regulation of biological quality#GO:0065008;inorganic ion homeostasis#GO:0098771;regulation of muscle contraction#GO:0006937;circulatory system process#GO:0003013;calcium ion homeostasis#GO:0055074 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 Endothelin signaling pathway#P00019>Big ET1-4#P00574;Endothelin signaling pathway#P00019>ET1-4#P00588 GORGO|Ensembl=ENSGGOG00000011612.3|UniProtKB=G3R7J1 G3R7J1 ATRAID PTHR15926:SF1 ALL-TRANS RETINOIC ACID-INDUCED DIFFERENTIATION FACTOR ALL-TRANS RETINOIC ACID-INDUCED DIFFERENTIATION FACTOR GORGO|Ensembl=ENSGGOG00000007583.3|UniProtKB=G3QX93 G3QX93 ITSN2 PTHR11216:SF29 EH DOMAIN INTERSECTIN-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular localization#GO:0051641;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;synaptic vesicle endocytosis#GO:0048488;receptor-mediated endocytosis#GO:0006898;endosomal transport#GO:0016197;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000040785.1|UniProtKB=A0A2I2YED5 A0A2I2YED5 PTHR13479:SF57 30S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000040223.1|UniProtKB=A0A2I2ZBW7 A0A2I2ZBW7 LIN28A PTHR46109:SF2 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010840.3|UniProtKB=G3R5J2 G3R5J2 RIPK2 PTHR44329:SF9 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 2 protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;defense response to other organism#GO:0098542;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cell communication#GO:0007154;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000021939.2|UniProtKB=G3S4K2 G3S4K2 KITLG PTHR11574:SF0 KIT LIGAND KIT LIGAND biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of cell population proliferation#GO:0008284 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000039541.1|UniProtKB=A0A2I2ZK72 A0A2I2ZK72 PTHR24207:SF1 ZYX102 PROTEIN FILAMIN-BINDING LIM PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 intracellular organelle#GO:0043229;stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228;cell junction#GO:0030054;actomyosin#GO:0042641;actin cytoskeleton#GO:0015629;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000009121.4|UniProtKB=A0A2I2Y1U6 A0A2I2Y1U6 RAPGEF4 PTHR23113:SF175 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000024567.2|UniProtKB=G3S8K7 G3S8K7 USP1 PTHR24006:SF905 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 1 cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000013403.3|UniProtKB=A0A2I2YRT5 A0A2I2YRT5 LOC101140953 PTHR24089:SF770 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SLC25A24 phosphate transmembrane transporter activity#GO:0005315;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;purine nucleotide transmembrane transporter activity#GO:0015216 cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000000385.3|UniProtKB=G3QDQ6 G3QDQ6 RFX1 PTHR12619:SF23 RFX TRANSCRIPTION FACTOR FAMILY MHC CLASS II REGULATORY FACTOR RFX1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000004022.3|UniProtKB=G3QN44 G3QN44 LOC101150033 PTHR24300:SF48 CYTOCHROME P450 508A4-RELATED VITAMIN D 25-HYDROXYLASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;steroid metabolic process#GO:0008202;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;vitamin D metabolic process#GO:0042359 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000017164.3|UniProtKB=G3RLU1 G3RLU1 LAMC3 PTHR10574:SF240 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-3 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tissue development#GO:0009888;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667 cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000026314.2|UniProtKB=G3S533 G3S533 CPA3 PTHR11705:SF65 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B MAST CELL CARBOXYPEPTIDASE A peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000024361.2|UniProtKB=A0A2I2YQW7 A0A2I2YQW7 C1H1orf43 PTHR21425:SF2 NICE-3 LIPID TRANSPORT AUXILIARY PROTEIN 1 localization#GO:0051179;import into cell#GO:0098657;endocytosis#GO:0006897;establishment of localization#GO:0051234;transport#GO:0006810;phagocytosis#GO:0006909 GORGO|Ensembl=ENSGGOG00000004094.3|UniProtKB=G3QNB0 G3QNB0 PTHR13206:SF0 UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN E3 UBIQUITIN-PROTEIN LIGASE FANCL catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012574.3|UniProtKB=G3RA14 G3RA14 SFRP5 PTHR11309:SF46 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 5 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434 GORGO|Ensembl=ENSGGOG00000013739.3|UniProtKB=A0A2I2Y682 A0A2I2Y682 GFM2 PTHR43261:SF9 TRANSLATION ELONGATION FACTOR G-RELATED RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 translation factor#PC00223;translational protein#PC00263;translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000034909.2|UniProtKB=G3SKM9 G3SKM9 PNMA3 PTHR23095:SF22 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN MA3 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000002348.3|UniProtKB=G3QIU9 G3QIU9 ARFGEF3 PTHR10663:SF344 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 3 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000004939.3|UniProtKB=G3RYA9 G3RYA9 HIP1R PTHR10407:SF10 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN-INTERACTING PROTEIN 1-RELATED PROTEIN phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;protein-membrane adaptor activity#GO:0043495;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 endocytosis#GO:0006897;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;actin cytoskeleton organization#GO:0030036;regulation of ERBB signaling pathway#GO:1901184;positive regulation of signal transduction#GO:0009967;supramolecular fiber organization#GO:0097435;localization#GO:0051179;actin filament-based process#GO:0030029;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;actin filament organization#GO:0007015;establishment of localization#GO:0051234;transport#GO:0006810;regulation of response to stimulus#GO:0048583 cytoskeleton#GO:0005856;clathrin-coated vesicle#GO:0030136;membraneless organelle#GO:0043228;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;cortical cytoskeleton#GO:0030863;intracellular vesicle#GO:0097708;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Huntington disease#P00029>Hip-12#P00763 GORGO|Ensembl=ENSGGOG00000022078.2|UniProtKB=P0CF78 P0CF78 APOC1A PTHR16565:SF3 APOLIPOPROTEIN C-I APOLIPOPROTEIN C-I, ACIDIC FORM molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;fatty acid binding#GO:0005504;molecular function inhibitor activity#GO:0140678;lipid binding#GO:0008289;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;organic acid binding#GO:0043177 glycerolipid metabolic process#GO:0046486;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238;regulation of lipid catabolic process#GO:0050994;regulation of biological process#GO:0050789;negative regulation of catabolic process#GO:0009895;regulation of lipid metabolic process#GO:0019216;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;neutral lipid metabolic process#GO:0006638;plasma lipoprotein particle clearance#GO:0034381;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of catabolic process#GO:0009894;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;acylglycerol metabolic process#GO:0006639;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;very-low-density lipoprotein particle#GO:0034361;plasma lipoprotein particle#GO:0034358;high-density lipoprotein particle#GO:0034364;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;lipoprotein particle#GO:1990777 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000007406.3|UniProtKB=G3RXV2 G3RXV2 KYNU PTHR14084:SF0 KYNURENINASE KYNURENINASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000005679.3|UniProtKB=A0A2I2Z1V7 A0A2I2Z1V7 TWF1 PTHR13759:SF8 TWINFILIN TWINFILIN-1 cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;actin monomer binding#GO:0003785;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;cellular component disassembly#GO:0022411;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;protein-containing complex disassembly#GO:0032984;regulation of actin filament depolymerization#GO:0030834;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;regulation of cell projection assembly#GO:0060491;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;protein depolymerization#GO:0051261;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;regulation of plasma membrane bounded cell projection organization#GO:0120035 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000012473.3|UniProtKB=A0A2I2YPK9 A0A2I2YPK9 ZNF677 PTHR23226:SF305 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 677 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014898.3|UniProtKB=G3RQD2 G3RQD2 PTHR23262:SF173 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-5 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000006515.3|UniProtKB=G3QUH3 G3QUH3 TRIM21 PTHR24103:SF46 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM21 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of catabolic process#GO:0009894;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;response to biotic stimulus#GO:0009607;positive regulation of autophagy#GO:0010508;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;immune system process#GO:0002376;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002885.3|UniProtKB=G3QK72 G3QK72 WDR7 PTHR44099:SF3 RABCONNECTIN-3B, ISOFORM A WD REPEAT-CONTAINING PROTEIN 7 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008115.3|UniProtKB=Q7JK24 Q7JK24 B3GALT1 PTHR11214:SF20 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;oligosaccharide biosynthetic process#GO:0009312;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000016147.3|UniProtKB=G3RJ77 G3RJ77 DEUP1 PTHR18875:SF5 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO DEUTEROSOME ASSEMBLY PROTEIN 1 cell differentiation#GO:0030154;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;centriole replication#GO:0007099;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cellular component assembly#GO:0022607;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;developmental process#GO:0032502 organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000014866.3|UniProtKB=G3RFX4 G3RFX4 MCM2 PTHR11630:SF44 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM2 ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA replication initiation#GO:0006270;DNA damage response#GO:0006974;DNA repair#GO:0006281;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;mitotic cell cycle process#GO:1903047;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;MCM complex#GO:0042555;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000024516.2|UniProtKB=G3SFY1 G3SFY1 THAP8 PTHR46927:SF2 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 8 GORGO|Ensembl=ENSGGOG00000015381.3|UniProtKB=A0A2I2ZPF8 A0A2I2ZPF8 CLXN PTHR23055:SF75 CALCIUM BINDING PROTEINS CALAXIN metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000013360.3|UniProtKB=G3RC15 G3RC15 RCAN3 PTHR10300:SF6 CALCIPRESSIN CALCIPRESSIN-3 molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000022134.2|UniProtKB=G3SIQ0 G3SIQ0 NFIB PTHR11492:SF4 NUCLEAR FACTOR I NUCLEAR FACTOR 1 B-TYPE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000022649.2|UniProtKB=G3SDQ7 G3SDQ7 PTHR10114:SF9 60S RIBOSOMAL PROTEIN L36 LARGE RIBOSOMAL SUBUNIT PROTEIN EL36 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008161.3|UniProtKB=G3SDQ2 G3SDQ2 PTHR23101:SF58 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR 3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000014102.3|UniProtKB=A0A2I2Z438 A0A2I2Z438 LACTBL1 PTHR22935:SF95 PENICILLIN-BINDING PROTEIN BETA-LACTAMASE-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000023104.2|UniProtKB=G3S610 G3S610 MND1 PTHR31398:SF0 MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;cellular process#GO:0009987;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000015038.3|UniProtKB=G3RGD1 G3RGD1 RPSA PTHR11489:SF17 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2-RELATED structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein-containing complex organization#GO:0043933;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;translation#GO:0006412;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010189.3|UniProtKB=A0A2I2Z3R9 A0A2I2Z3R9 CD82 PTHR19282:SF44 TETRASPANIN CD82 ANTIGEN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 p53 pathway#P00059>KAI#G04704 GORGO|Ensembl=ENSGGOG00000001795.3|UniProtKB=G3QHE0 G3QHE0 SCGB1A1 PTHR10136:SF6 SECRETOGLOBIN FAMILY 1 MEMBER UTEROGLOBIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000002817.3|UniProtKB=G3S1I6 G3S1I6 LRP2BP PTHR44554:SF1 LRP2-BINDING PROTEIN LRP2-BINDING PROTEIN GORGO|Ensembl=ENSGGOG00000009586.3|UniProtKB=G3R2B8 G3R2B8 ZNF512 PTHR22979:SF2 ZINC FINGER PROTEIN-RELATED ZINC FINGER PROTEIN 512 GORGO|Ensembl=ENSGGOG00000016388.3|UniProtKB=G3RJU3 G3RJU3 CHRNB1 PTHR18945:SF477 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT BETA passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;system process#GO:0003008;muscle contraction#GO:0006936;transport#GO:0006810;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;multicellular organismal process#GO:0032501;acetylcholine receptor signaling pathway#GO:0095500;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;neuromuscular process#GO:0050905;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;striated muscle contraction#GO:0006941;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;response to chemical#GO:0042221;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;nervous system process#GO:0050877;response to stimulus#GO:0050896;skeletal muscle contraction#GO:0003009;signaling#GO:0023052;regulation of biological process#GO:0050789;muscle system process#GO:0003012 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;transporter complex#GO:1990351;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;transmembrane transporter complex#GO:1902495 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095 GORGO|Ensembl=ENSGGOG00000025460.2|UniProtKB=G3S2V1 G3S2V1 LRRIQ3 PTHR46723:SF1 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000004125.3|UniProtKB=G3RUD6 G3RUD6 MED14 PTHR12809:SF2 MEDIATOR COMPLEX SUBUNIT MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000000140.3|UniProtKB=G3QD36 G3QD36 LOC101127800 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;aspartic protease#PC00053 GORGO|Ensembl=ENSGGOG00000005741.3|UniProtKB=G3QSI0 G3QSI0 ATP5ME PTHR12427:SF1 ATP SYNTHASE E CHAIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT E, MITOCHONDRIAL proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;small molecule metabolic process#GO:0044281;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333 cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703 ATP synthase#PC00002;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000013640.3|UniProtKB=G3RCS2 G3RCS2 ZNF536 PTHR45925:SF2 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 536 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000006407.2|UniProtKB=A0A2I2ZAN2 A0A2I2ZAN2 VPS29 PTHR11124:SF12 VACUOLAR SORTING PROTEIN VPS29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 29 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 vesicle#GO:0031982;retromer complex#GO:0030904;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000042269.1|UniProtKB=A0A2I2YT27 A0A2I2YT27 PTHR23267:SF399 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000009813.3|UniProtKB=A0A2I2ZYM7 A0A2I2ZYM7 DCTN4 PTHR13034:SF2 DYNACTIN P62 SUBUNIT DYNACTIN SUBUNIT 4 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;transport#GO:0006810;cellular process#GO:0009987;intracellular transport#GO:0046907 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232 microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000000266.3|UniProtKB=A0A2I2ZHI2 A0A2I2ZHI2 POLR3G PTHR15367:SF3 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7 cell population proliferation#GO:0008283;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000001290.3|UniProtKB=G3QG23 G3QG23 MOCS2 PTHR23404:SF2 MOLYBDOPTERIN SYNTHASE RELATED MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000010521.3|UniProtKB=G3R4Q1 G3R4Q1 PRSS27 PTHR24253:SF144 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27 peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000040562.1|UniProtKB=A0A2I2YVA1 A0A2I2YVA1 LOC101136189 PTHR26453:SF639 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2M2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014757.3|UniProtKB=G3RP94 G3RP94 FRMD4A PTHR46079:SF3 FERM DOMAIN-CONTAINING PROTEIN 4 FERM DOMAIN-CONTAINING PROTEIN 4A cell junction#GO:0030054;tight junction#GO:0070160;adherens junction#GO:0005912;anchoring junction#GO:0070161;apical junction complex#GO:0043296;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 GORGO|Ensembl=ENSGGOG00000026107.2|UniProtKB=G3RSZ1 G3RSZ1 SSX4 PTHR14112:SF8 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX4 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000026618.2|UniProtKB=G3RTI6 G3RTI6 PTHR11267:SF210 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX20 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;embryonic organ development#GO:0048568;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;determination of left/right symmetry#GO:0007368;heart morphogenesis#GO:0003007;tube morphogenesis#GO:0035239;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;specification of symmetry#GO:0009799;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tube development#GO:0035295;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;regionalization#GO:0003002;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;morphogenesis of an epithelium#GO:0002009;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;left/right pattern formation#GO:0060972;cell fate specification#GO:0001708;determination of bilateral symmetry#GO:0009855;embryo development#GO:0009790;heart development#GO:0007507;cellular process#GO:0009987 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 GORGO|Ensembl=ENSGGOG00000017138.3|UniProtKB=G3SCR4 G3SCR4 ZNF627 PTHR24379:SF78 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 627 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012047.3|UniProtKB=G3R8N5 G3R8N5 LOC101124917 PTHR26453:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037562.1|UniProtKB=A0A2I2YGF1 A0A2I2YGF1 ABHD17A PTHR12277:SF52 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17A catalytic activity, acting on a protein#GO:0140096;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790 regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of postsynapse organization#GO:0099175;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of synapse organization#GO:0050807;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000023652.2|UniProtKB=G3S7T1 G3S7T1 TCEA1 PTHR11477:SF1 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036513.1|UniProtKB=A0A2I2ZAR6 A0A2I2ZAR6 PTHR10634:SF25 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 6 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein targeting#GO:0006605;establishment of protein localization#GO:0045184 GORGO|Ensembl=ENSGGOG00000016611.3|UniProtKB=G3RKE9 G3RKE9 DENND1A PTHR13196:SF22 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1A phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907 intracellular vesicle#GO:0097708;cytosol#GO:0005829;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000017052.3|UniProtKB=G3RLJ3 G3RLJ3 ANKRD31 PTHR24176:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 31-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 31 GORGO|Ensembl=ENSGGOG00000014516.3|UniProtKB=G3SJ74 G3SJ74 RAB11B PTHR47979:SF41 DRAB11-RELATED RAS-RELATED PROTEIN RAB-11B hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553 regulated exocytosis#GO:0045055;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;exocytosis#GO:0006887;secretion by cell#GO:0032940;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 G-protein#PC00020;small GTPase#PC00208 PDGF signaling pathway#P00047>Ras#P01154 GORGO|Ensembl=ENSGGOG00000008295.3|UniProtKB=G3RVS2 G3RVS2 LY75 PTHR22803:SF65 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED LYMPHOCYTE ANTIGEN 75 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000010311.3|UniProtKB=G3S918 G3S918 PTHR23226:SF452 ZINC FINGER AND SCAN DOMAIN-CONTAINING PAG-3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000000343.3|UniProtKB=G3QDL4 G3QDL4 CCDC17 PTHR33820:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 GORGO|Ensembl=ENSGGOG00000011332.3|UniProtKB=A0A2I2YFV9 A0A2I2YFV9 SPEF2 PTHR14919:SF1 KPL2-RELATED SPERM FLAGELLA AND CILIA-ASSOCIATED PROTEIN 2 cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000009049.3|UniProtKB=A0A2I2ZV69 A0A2I2ZV69 BBOF1 PTHR14845:SF5 COILED-COIL DOMAIN-CONTAINING 166 BASAL BODY-ORIENTATION FACTOR 1 GORGO|Ensembl=ENSGGOG00000014873.3|UniProtKB=G3RFY1 G3RFY1 PTHR47136:SF1 SYNEMIN SYNEMIN cytoskeletal protein binding#GO:0008092;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;structural molecule activity#GO:0005198;protein binding#GO:0005515 system process#GO:0003008;neuromuscular process#GO:0050905;muscle contraction#GO:0006936;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;muscle system process#GO:0003012 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cell periphery#GO:0071944;contractile muscle fiber#GO:0043292;membrane#GO:0016020;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;sarcolemma#GO:0042383;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000010917.3|UniProtKB=A0A2I2YAW1 A0A2I2YAW1 UNC80 PTHR31781:SF1 UNC80 PROTEIN UNC-80 HOMOLOG channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;regulation of multicellular organismal process#GO:0051239;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of system process#GO:0044057;homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 neuron projection#GO:0043005;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;axon#GO:0030424;sodium channel complex#GO:0034706;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 GORGO|Ensembl=ENSGGOG00000012912.3|UniProtKB=G3RAY2 G3RAY2 PTHR13817:SF55 TITIN PROTEIN SIDEKICK-1 animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;system development#GO:0048731;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;synapse assembly#GO:0007416;cell junction organization#GO:0034330;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;homophilic cell-cell adhesion#GO:0007156;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000007136.3|UniProtKB=G3S269 G3S269 PTHR15566:SF6 POM121-LIKE POM121-LIKE PROTEIN 1-RELATED GORGO|Ensembl=ENSGGOG00000006007.3|UniProtKB=G3QT65 G3QT65 GPR19 PTHR24241:SF182 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 19-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000001592.3|UniProtKB=G3QGV4 G3QGV4 BRINP2 PTHR15564:SF8 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 2 negative regulation of cell cycle#GO:0045786;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;negative regulation of mitotic cell cycle#GO:0045930;generation of neurons#GO:0048699;response to oxygen-containing compound#GO:1901700;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of mitotic cell cycle#GO:0007346;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;cell body#GO:0044297;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447 GORGO|Ensembl=ENSGGOG00000025993.2|UniProtKB=G3RT18 G3RT18 PTHR43943:SF1 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 4-LIKE 1-RELATED catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 primary metabolic process#GO:0044238;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;terpenoid metabolic process#GO:0006721 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000027837.2|UniProtKB=G3SH75 G3SH75 MAP6D1 PTHR14759:SF37 STOP PROTEIN MAP6 DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cis-Golgi network#GO:0005801;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;microtubule#GO:0005874;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000004275.3|UniProtKB=G3QNR5 G3QNR5 ACKR3 PTHR10489:SF931 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 3 cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;chemotaxis#GO:0006935;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000036337.1|UniProtKB=A0A2I2Y749 A0A2I2Y749 PTHR18901:SF39 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE 5'-PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000008166.3|UniProtKB=A0A2I2ZM81 A0A2I2ZM81 TCF12 PTHR11793:SF11 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR 12 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000013277.3|UniProtKB=A0A2I2YI73 A0A2I2YI73 FAT4 PTHR24025:SF31 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000008542.3|UniProtKB=G3QZN8 G3QZN8 RNF14 PTHR11685:SF290 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF14 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000016638.3|UniProtKB=G3RKH1 G3RKH1 ZDHHC7 PTHR22883:SF49 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC7 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;protein localization to cell periphery#GO:1990778;protein targeting to membrane#GO:0006612;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;protein targeting#GO:0006605;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007861.3|UniProtKB=G3QXW7 G3QXW7 NDUFB11 PTHR13327:SF0 NADH-UBIQUINONE OXIDOREDUCTASE ESSS SUBUNIT, MITOCHONDRIAL PRECURSOR NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 11, MITOCHONDRIAL respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000782.3|UniProtKB=A0A2I2YKL3 A0A2I2YKL3 MED16 PTHR13224:SF6 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 16 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000004719.3|UniProtKB=G3QPW5 G3QPW5 DNAJB4 PTHR24078:SF288 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 4 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 metabolic process#GO:0008152;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;protein folding#GO:0006457;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000013075.3|UniProtKB=A0A2I2ZXE8 A0A2I2ZXE8 LETM2 PTHR14009:SF7 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN LETM2, MITOCHONDRIAL transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular component organization#GO:0016043;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;mitochondrial calcium ion transmembrane transport#GO:0006851;organelle organization#GO:0006996;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;mitochondrion organization#GO:0007005;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;calcium ion transport#GO:0006816 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024529.2|UniProtKB=A0A2I2YWB5 A0A2I2YWB5 PTHR11655:SF28 60S/50S RIBOSOMAL PROTEIN L6/L9 LARGE RIBOSOMAL SUBUNIT PROTEIN UL6 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004404.3|UniProtKB=G3SG37 G3SG37 PTHR23075:SF2 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3B mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008537.3|UniProtKB=G3QZN7 G3QZN7 GDA PTHR11271:SF6 GUANINE DEAMINASE GUANINE DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914 purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleobase catabolic process#GO:0006145;purine-containing compound catabolic process#GO:0072523;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 deaminase#PC00088 Purine metabolism#P02769>Guanine Deaminase#P03118;Xanthine and guanine salvage pathway#P02788>Guanine deaminase#P03249 GORGO|Ensembl=ENSGGOG00000007852.3|UniProtKB=A0A2I2YFQ1 A0A2I2YFQ1 LNPK PTHR22166:SF12 ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum tubular network#GO:0071782;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000009639.3|UniProtKB=G3R2G3 G3R2G3 PTHR10010:SF21 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2A phosphate transmembrane transporter activity#GO:0005315;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 homeostatic process#GO:0042592;phosphate ion transport#GO:0006817;transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 apical plasma membrane#GO:0016324;membrane#GO:0016020;vesicle#GO:0031982;brush border#GO:0005903;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical part of cell#GO:0045177;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000000858.3|UniProtKB=A0A2I2ZUH8 A0A2I2ZUH8 PODXL PTHR12067:SF5 PODOCALYXIN PODOCALYXIN regulation of cell projection assembly#GO:0060491;regulation of biological process#GO:0050789;positive regulation of cell adhesion#GO:0045785;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of cell-cell adhesion#GO:0022409;biological regulation#GO:0065007;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of cell adhesion#GO:0007162;cell migration#GO:0016477;regulation of cell adhesion#GO:0030155 cytoskeleton#GO:0005856;apical part of cell#GO:0045177;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;cell projection membrane#GO:0031253;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000037911.1|UniProtKB=A0A2I2YNX0 A0A2I2YNX0 PPM1L PTHR13832:SF827 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1L catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000005131.3|UniProtKB=G3QQZ7 G3QQZ7 ADIPOR1 PTHR20855:SF40 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cellular response to chemical stimulus#GO:0070887;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>AdipoR1/R2#P06706 GORGO|Ensembl=ENSGGOG00000014242.3|UniProtKB=G3REB6 G3REB6 ERCC4 PTHR10150:SF0 DNA REPAIR ENDONUCLEASE XPF DNA REPAIR ENDONUCLEASE XPF DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;DNA binding#GO:0003677;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;damaged DNA binding#GO:0003684;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 DNA damage response#GO:0006974;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;resolution of meiotic recombination intermediates#GO:0000712;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;organelle fission#GO:0048285;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;homologous recombination#GO:0035825;reproductive process#GO:0022414;DNA recombination#GO:0006310;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000004521.3|UniProtKB=A0A2I2YG74 A0A2I2YG74 LOC101136273 PTHR10829:SF12 CORTACTIN AND DREBRIN DREBRIN-LIKE PROTEIN actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008 site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;actin filament#GO:0005884;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;glutamatergic synapse#GO:0098978;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;lamellipodium#GO:0030027;cell periphery#GO:0071944;neuron projection#GO:0043005;cell leading edge#GO:0031252 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000015253.3|UniProtKB=G3RVG0 G3RVG0 IKBKE PTHR22969:SF10 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT EPSILON protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of biosynthetic process#GO:0009891;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;positive regulation of type I interferon production#GO:0032481;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;positive regulation of response to biotic stimulus#GO:0002833;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of cytokine production#GO:0001817;activation of innate immune response#GO:0002218;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;positive regulation of response to external stimulus#GO:0032103;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>IKKepsilon#P01372;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871 GORGO|Ensembl=ENSGGOG00000006415.3|UniProtKB=G3QU76 G3QU76 ZNF697 PTHR23226:SF207 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 697 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007157.3|UniProtKB=G3RWY0 G3RWY0 NMD3 PTHR12746:SF2 NONSENSE-MEDIATED MRNA DECAY PROTEIN 3 60S RIBOSOMAL EXPORT PROTEIN NMD3 ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;ribosomal large subunit export from nucleus#GO:0000055;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000004435.3|UniProtKB=G3QP65 G3QP65 XYLT1 PTHR46025:SF2 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE 1 pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285;UDP-xylosyltransferase activity#GO:0035252;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004065.3|UniProtKB=G3QN84 G3QN84 TKFC PTHR28629:SF4 TRIOKINASE/FMN CYCLASE TRIOKINASE_FMN CYCLASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cyclase#PC00079 GORGO|Ensembl=ENSGGOG00000014359.3|UniProtKB=G3REL2 G3REL2 LOC101126380 PTHR26453:SF634 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014426.3|UniProtKB=G3RET0 G3RET0 SURF6 PTHR14369:SF0 SURFEIT LOCUS PROTEIN 6 SURFEIT LOCUS PROTEIN 6 binding#GO:0005488;nucleic acid binding#GO:0003676;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;molecular condensate scaffold activity#GO:0140693;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000042068.1|UniProtKB=A0A2I2Z474 A0A2I2Z474 PTHR23266:SF415 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-8 antigen binding#GO:0003823;binding#GO:0005488 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000015188.3|UniProtKB=G3RGR6 G3RGR6 NHLRC2 PTHR46388:SF2 NHL REPEAT-CONTAINING PROTEIN 2 NHL REPEAT-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000028551.2|UniProtKB=G3S2K8 G3S2K8 KCNJ5 PTHR11767:SF52 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 4 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215 cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 GORGO|Ensembl=ENSGGOG00000022586.2|UniProtKB=A0A2I2ZMH3 A0A2I2ZMH3 PTHR44086:SF15 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000003143.3|UniProtKB=G3QKV6 G3QKV6 IGFBP6 PTHR11551:SF14 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 6 binding#GO:0005488;protein binding#GO:0005515;growth factor binding#GO:0019838 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000005498.4|UniProtKB=G3QRW8 G3QRW8 ELMOD1 PTHR12771:SF18 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cilium#GO:0005929;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;synapse#GO:0045202;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008807.3|UniProtKB=G3R0C5 G3R0C5 LOC101137143 PTHR24257:SF11 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 3A serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004303.3|UniProtKB=G3S310 G3S310 IL19 PTHR48482:SF3 INTERLEUKIN-19-RELATED INTERLEUKIN-19 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010861.3|UniProtKB=A0A2I2Y9P0 A0A2I2Y9P0 CAMSAP2 PTHR21595:SF1 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein depolymerization#GO:1901880;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;negative regulation of cellular process#GO:0048523;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;cytoplasmic microtubule organization#GO:0031122;regulation of cellular process#GO:0050794;negative regulation of biological process#GO:0048519;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;negative regulation of cytoskeleton organization#GO:0051494;microtubule cytoskeleton organization#GO:0000226;negative regulation of protein-containing complex disassembly#GO:0043242;supramolecular fiber organization#GO:0097435;regulation of microtubule-based process#GO:0032886 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule end#GO:1990752;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 GORGO|Ensembl=ENSGGOG00000000977.3|UniProtKB=G3RRL0 G3RRL0 ARG1 PTHR43782:SF2 ARGINASE ARGINASE-1 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;negative regulation of cell activation#GO:0050866;negative regulation of cell population proliferation#GO:0008285;negative regulation of cell adhesion#GO:0007162;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of immune system process#GO:0002683;amino acid metabolic process#GO:0006520;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238;regulation of T cell proliferation#GO:0042129;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;negative regulation of leukocyte cell-cell adhesion#GO:1903038;metabolic process#GO:0008152;regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130;regulation of mononuclear cell proliferation#GO:0032944;cellular process#GO:0009987;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;arginine metabolic process#GO:0006525;oxoacid metabolic process#GO:0043436;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;carboxylic acid metabolic process#GO:0019752;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;small molecule metabolic process#GO:0044281;regulation of lymphocyte activation#GO:0051249 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000332.3|UniProtKB=A0A2I2ZLP6 A0A2I2ZLP6 RIMKLB PTHR21621:SF5 RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN BETA-CITRYLGLUTAMATE SYNTHASE B ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000034855.2|UniProtKB=A0A2I2YXL9 A0A2I2YXL9 ADI1 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000004067.3|UniProtKB=G3RNA5 G3RNA5 HNRNPL PTHR15592:SF20 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000001186.3|UniProtKB=G3RS16 G3RS16 ITPKC PTHR12400:SF106 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE C phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;organophosphate biosynthetic process#GO:0090407;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000008172.3|UniProtKB=G3QYP8 G3QYP8 BECN2 PTHR12768:SF5 BECLIN 1 BECLIN-2 phosphatidylinositol 3-kinase binding#GO:0043548;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;mitophagy#GO:0000423;establishment of localization#GO:0051234;cellular response to starvation#GO:0009267;intracellular transport#GO:0046907;autophagy of mitochondrion#GO:0000422;cellular response to nutrient levels#GO:0031669;vacuolar transport#GO:0007034;transport#GO:0006810;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;catabolic process#GO:0009056;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716 membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex, class III#GO:0035032;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000024483.2|UniProtKB=A0A2I2ZTV0 A0A2I2ZTV0 PTHR10177:SF391 CYCLINS CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000015388.3|UniProtKB=G3RR15 G3RR15 SERP1 PTHR15601:SF14 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN 1 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000005119.3|UniProtKB=A0A2I2YR08 A0A2I2YR08 USP28 PTHR24006:SF678 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 28 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;signaling#GO:0023052;cellular response to stress#GO:0033554;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;DNA integrity checkpoint signaling#GO:0031570;response to stress#GO:0006950;signal transduction#GO:0007165;regulation of protein stability#GO:0031647;cellular process#GO:0009987;cell cycle checkpoint signaling#GO:0000075;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000002274.3|UniProtKB=A0A2I2ZEQ8 A0A2I2ZEQ8 ZFAND3 PTHR10634:SF67 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 3 GORGO|Ensembl=ENSGGOG00000004642.3|UniProtKB=G3QPP8 G3QPP8 FABP6 PTHR11955:SF69 FATTY ACID BINDING PROTEIN GASTROTROPIN organic acid binding#GO:0043177;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;lipid binding#GO:0008289;fatty acid binding#GO:0005504 fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;lipid transport#GO:0006869;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000039270.1|UniProtKB=A0A2I2ZCG6 A0A2I2ZCG6 TRGV10 PTHR19256:SF40 T-CELL RECEPTOR GAMMA CHAIN NON-FUNCTIONAL T CELL RECEPTOR GAMMA VARIABLE 10-RELATED immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000013397.3|UniProtKB=G3RC46 G3RC46 PIERCE1 PTHR20899:SF1 PIERCE HOMOLOG PIERCER OF MICROTUBULE WALL 1 PROTEIN GORGO|Ensembl=ENSGGOG00000004119.3|UniProtKB=G3QNC8 G3QNC8 GLYAT PTHR15298:SF9 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000010110.3|UniProtKB=A0A2I2YFY6 A0A2I2YFY6 MOV10L1 PTHR45418:SF1 CANCER/TESTIS ANTIGEN 55 CANCER_TESTIS ANTIGEN 55 GORGO|Ensembl=ENSGGOG00000006658.3|UniProtKB=G3QUW1 G3QUW1 GLMN PTHR15430:SF2 GLOMULIN GLOMULIN molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;blood vessel morphogenesis#GO:0048514;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;anatomical structure development#GO:0048856;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;tube development#GO:0035295;regulation of proteasomal protein catabolic process#GO:0061136;vasculogenesis#GO:0001570;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000004014.3|UniProtKB=A0A2I2Z327 A0A2I2Z327 APLP1 PTHR23103:SF13 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID BETA PRECURSOR LIKE PROTEIN 1 signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000005474.3|UniProtKB=A0A2I2YTD3 A0A2I2YTD3 ARL6 PTHR11711:SF21 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6 nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cilium organization#GO:0044782;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;organelle assembly#GO:0070925;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;cilium assembly#GO:0060271 organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000004897.3|UniProtKB=G3QQD3 G3QQD3 KCNJ1 PTHR11767:SF6 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 1 transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000016430.3|UniProtKB=G3RJZ1 G3RJZ1 RAPGEF3 PTHR23113:SF24 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 3 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of developmental process#GO:0050793;positive regulation of angiogenesis#GO:0045766;cellular response to stimulus#GO:0051716;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of angiogenesis#GO:0045765;Ras protein signal transduction#GO:0007265;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of anatomical structure morphogenesis#GO:0022603;regulation of vasculature development#GO:1901342;positive regulation of developmental process#GO:0051094 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000007237.3|UniProtKB=G3QWC5 G3QWC5 MAP1S PTHR13843:SF11 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1S protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;tubulin binding#GO:0015631 plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;dendrite development#GO:0016358;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;axon development#GO:0061564;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of microtubule-based process#GO:0032886;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;neuron projection#GO:0043005;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cell body#GO:0044297;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000013696.3|UniProtKB=G3RCX8 G3RCX8 PCF11 PTHR15921:SF3 PRE-MRNA CLEAVAGE COMPLEX II PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11 RNA polymerase II complex binding#GO:0000993;RNA binding#GO:0003723;protein binding#GO:0005515;enzyme binding#GO:0019899;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase binding#GO:0070063 transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;macromolecule metabolic process#GO:0043170;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000000437.3|UniProtKB=G3QDV0 G3QDV0 VRTN PTHR16081:SF0 VERTNIN VERTNIN regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000041962.1|UniProtKB=A0A2I2YEI1 A0A2I2YEI1 PTHR22702:SF2 PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN PA DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000002268.3|UniProtKB=G3SBU6 G3SBU6 NFE2L1 PTHR24411:SF31 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR ENDOPLASMIC RETICULUM MEMBRANE SENSOR NFE2L1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000022216.2|UniProtKB=G3RUK7 G3RUK7 LOC101141087 PTHR11620:SF106 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000040563.1|UniProtKB=A0A2I2Y585 A0A2I2Y585 PTHR23212:SF0 BRAIN ACID SOLUBLE PROTEIN 1 BRAIN ACID SOLUBLE PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000011160.3|UniProtKB=G3R6C8 G3R6C8 CENPW PTHR34832:SF1 CENTROMERE PROTEIN W CENTROMERE PROTEIN W cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;kinetochore organization#GO:0051383;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 GORGO|Ensembl=ENSGGOG00000004722.3|UniProtKB=G3QPX3 G3QPX3 IQCH PTHR14465:SF0 IQ DOMAIN-CONTAINING PROTEIN H IQ DOMAIN-CONTAINING PROTEIN H GORGO|Ensembl=ENSGGOG00000013915.3|UniProtKB=G3SDR1 G3SDR1 LMCD1 PTHR24211:SF0 LIM DOMAIN-CONTAINING PROTEIN LIM AND CYSTEINE-RICH DOMAINS PROTEIN 1 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of calcineurin-NFAT signaling cascade#GO:0070884;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of muscle system process#GO:0090257;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of signaling#GO:0023056;negative regulation of DNA-templated transcription#GO:0045892;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of signal transduction#GO:0009967;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of calcium-mediated signaling#GO:0050850 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004329.3|UniProtKB=G3QNW9 G3QNW9 HNF1A PTHR11568:SF4 HEPATOCYTE NUCLEAR FACTOR 1 HEPATOCYTE NUCLEAR FACTOR 1-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000004698.3|UniProtKB=G3QPU8 G3QPU8 LTB4R PTHR24230:SF51 G-PROTEIN COUPLED RECEPTOR LEUKOTRIENE B4 RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000023553.2|UniProtKB=G3S1G0 G3S1G0 SLC39A1 PTHR13589:SF6 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 2 transcription regulator activity#GO:0140110;binding#GO:0005488;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;DNA-binding transcription factor binding#GO:0140297;transcription coactivator activity#GO:0003713;protein binding#GO:0005515 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000005023.3|UniProtKB=G3RY83 G3RY83 BTRC PTHR14604:SF5 WD40 REPEAT PF20 F-BOX_WD REPEAT-CONTAINING PROTEIN 1A enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 microtubule or microtubule-binding cytoskeletal protein#PC00157 Wnt signaling pathway#P00057>betaTrCP#P01454;Hedgehog signaling pathway#P00025>Slimb#P00683 GORGO|Ensembl=ENSGGOG00000026253.2|UniProtKB=G3S9J8 G3S9J8 PPCS PTHR12290:SF2 CORNICHON-RELATED PHOSPHOPANTOTHENATE--CYSTEINE LIGASE membrane traffic protein#PC00150 Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882 GORGO|Ensembl=ENSGGOG00000003118.3|UniProtKB=G3QKT0 G3QKT0 PTHR13578:SF18 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL3-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;chromatin binding#GO:0003682;protein binding#GO:0005515 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;positive regulation of RNA metabolic process#GO:0051254;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 PcG protein complex#GO:0031519;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000003512.3|UniProtKB=A0A2I2ZK42 A0A2I2ZK42 DSTYK PTHR46392:SF1 DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE DUAL SERINE_THREONINE AND TYROSINE PROTEIN KINASE positive regulation of signal transduction#GO:0009967;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;positive regulation of cellular process#GO:0048522;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;response to fibroblast growth factor#GO:0071774;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000000094.3|UniProtKB=G3QCZ1 G3QCZ1 KLHL30 PTHR24412:SF398 KELCH PROTEIN KELCH-LIKE PROTEIN 30 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003101.3|UniProtKB=G3QKR8 G3QKR8 FAM20A PTHR12450:SF12 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 PSEUDOKINASE FAM20A protein kinase activator activity#GO:0030295;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biomineral tissue development#GO:0031214;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;enamel mineralization#GO:0070166;anatomical structure formation involved in morphogenesis#GO:0048646;animal organ development#GO:0048513;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;amelogenesis#GO:0097186;odontogenesis#GO:0042476;odontogenesis of dentin-containing tooth#GO:0042475;animal organ morphogenesis#GO:0009887;tissue development#GO:0009888 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000014592.3|UniProtKB=G3RF74 G3RF74 FBXO42 PTHR46432:SF1 F-BOX ONLY PROTEIN 42 F-BOX ONLY PROTEIN 42 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005 GORGO|Ensembl=ENSGGOG00000014318.3|UniProtKB=G3SJA7 G3SJA7 SIDT2 PTHR12185:SF16 SID1 TRANSMEMBRANE FAMILY MEMEBER SID1 TRANSMEMBRANE FAMILY MEMBER 2 nucleobase-containing compound transmembrane transporter activity#GO:0015932;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;transport#GO:0006810;localization#GO:0051179;nucleic acid transport#GO:0050657;establishment of localization#GO:0051234 vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000014367.3|UniProtKB=G3REL9 G3REL9 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of protein stability#GO:0031647;regulation of apoptotic process#GO:0042981 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000043452.1|UniProtKB=A0A2I2ZW13 A0A2I2ZW13 PTHR12783:SF5 RALA BINDING PROTEIN 1 RALBP1 RALA-BINDING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;signaling#GO:0023052;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000009028.3|UniProtKB=G3RRV0 G3RRV0 TEC PTHR24418:SF219 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE TEC non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 GORGO|Ensembl=ENSGGOG00000007775.3|UniProtKB=G3QXQ0 G3QXQ0 CHMP4B PTHR22761:SF4 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4B vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;nucleus organization#GO:0006997;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;membrane assembly#GO:0071709;cellular localization#GO:0051641;localization#GO:0051179 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic side of plasma membrane#GO:0009898;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;vesicle#GO:0031982;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;nucleus#GO:0005634;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic side of membrane#GO:0098562 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011987.3|UniProtKB=A0A2I2YQ50 A0A2I2YQ50 TRPM6 PTHR13800:SF15 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 6 metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;kinase activity#GO:0016301;transporter activity#GO:0005215;transferase activity#GO:0016740;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;monoatomic cation channel activity#GO:0005261;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015455.3|UniProtKB=A0A2I2ZI90 A0A2I2ZI90 GRB7 PTHR11243:SF25 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Grb7#P00228 GORGO|Ensembl=ENSGGOG00000009241.3|UniProtKB=G3R1G1 G3R1G1 WBP2 PTHR31606:SF4 WW DOMAIN BINDING PROTEIN 2, ISOFORM E WW DOMAIN-BINDING PROTEIN 2 transcription coactivator activity#GO:0003713;chromatin DNA binding#GO:0031490;transcription coregulator activity#GO:0003712;DNA binding#GO:0003677;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007979.3|UniProtKB=G3SHA1 G3SHA1 MRM1 PTHR46103:SF3 RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA (guanine) methyltransferase activity#GO:0016435;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000038177.1|UniProtKB=A0A2I2ZCX7 A0A2I2ZCX7 GEMIN6 PTHR14710:SF2 GEM-ASSOCIATED PROTEIN 6 GEM-ASSOCIATED PROTEIN 6 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;SMN complex#GO:0032797 GORGO|Ensembl=ENSGGOG00000024597.2|UniProtKB=G3S5M1 G3S5M1 SPIC PTHR11849:SF17 ETS TRANSCRIPTION FACTOR SPI-C DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Interleukin signaling pathway#P00036>Ets#P00989 GORGO|Ensembl=ENSGGOG00000001209.3|UniProtKB=G3QFV9 G3QFV9 DTYMK PTHR10344:SF9 THYMIDYLATE KINASE THYMIDYLATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776 nucleoside diphosphate metabolic process#GO:0009132;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 nucleotide kinase#PC00172;kinase#PC00137;transferase#PC00220 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916 GORGO|Ensembl=ENSGGOG00000002837.3|UniProtKB=G3QK27 G3QK27 LOC101141689 PTHR48018:SF13 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010456.3|UniProtKB=A0A2I2Y385 A0A2I2Y385 VHL PTHR15160:SF17 VON HIPPEL-LINDAU PROTEIN VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR transcription corepressor activity#GO:0003714;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674;transcription regulator activity#GO:0140110;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;proteasomal protein catabolic process#GO:0010498;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>VHL#P00816 GORGO|Ensembl=ENSGGOG00000023232.2|UniProtKB=G3RZH0 G3RZH0 SEMA6A PTHR11036:SF12 SEMAPHORIN SEMAPHORIN-6A signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;regulation of neuron migration#GO:2001222;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000014229.3|UniProtKB=G3REA9 G3REA9 CPNE9 PTHR10857:SF112 COPINE COPINE-9 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to metal ion#GO:0010038;response to calcium ion#GO:0051592;response to chemical#GO:0042221;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000036331.1|UniProtKB=A0A2I2YDE8 A0A2I2YDE8 LOC109024193 PTHR24379:SF134 KRAB AND ZINC FINGER DOMAIN-CONTAINING RIKEN CDNA 2610008E11 GENE LIKE-RELATED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000040518.1|UniProtKB=A0A2I2YH81 A0A2I2YH81 SMIM7 PTHR28622:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 7 SMALL INTEGRAL MEMBRANE PROTEIN 7 GORGO|Ensembl=ENSGGOG00000014162.3|UniProtKB=A0A2I2ZWC9 A0A2I2ZWC9 SH3BP2 PTHR15126:SF4 SH3-BINDING SH3 DOMAIN-BINDING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000012165.3|UniProtKB=G3R905 G3R905 IL17RC PTHR15583:SF12 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR C signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to cytokine#GO:0034097;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010129.3|UniProtKB=A0A2I2YYL1 A0A2I2YYL1 PATJ PTHR19964:SF11 MULTIPLE PDZ DOMAIN PROTEIN INAD-LIKE PROTEIN cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043 tight junction#GO:0070160;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;apical junction complex#GO:0043296;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011101.3|UniProtKB=G3R689 G3R689 VCL PTHR46180:SF1 VINCULIN VINCULIN binding#GO:0005488;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cellular process#GO:0009987;cell adhesion#GO:0007155 focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;adherens junction#GO:0005912;cell-cell contact zone#GO:0044291;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 Gonadotropin-releasing hormone receptor pathway#P06664>Vinculin#P06771;Integrin signalling pathway#P00034>Vinculin#P00937 GORGO|Ensembl=ENSGGOG00000037794.1|UniProtKB=A0A2I2YXV7 A0A2I2YXV7 FOXN2 PTHR13962:SF19 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000002826.3|UniProtKB=G3QK17 G3QK17 JPH1 PTHR23085:SF6 GH28348P JUNCTOPHILIN-1 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;sarcoplasmic reticulum#GO:0016529;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528 GORGO|Ensembl=ENSGGOG00000005248.3|UniProtKB=G3QR98 G3QR98 TMEM45A PTHR16007:SF21 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45A GORGO|Ensembl=ENSGGOG00000014895.3|UniProtKB=A0A2I2YX18 A0A2I2YX18 USP19 PTHR21646:SF24 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 19 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000004177.3|UniProtKB=A0A2I2Z3D2 A0A2I2Z3D2 PTPRE PTHR19134:SF499 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE EPSILON hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000024802.2|UniProtKB=G3S8N2 G3S8N2 PTHR11961:SF15 CYTOCHROME C CYTOCHROME C, SOMATIC mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 ATP synthesis#P02721>Cyt C#P02798;Apoptosis signaling pathway#P00006>Cytochrome C#P00322 GORGO|Ensembl=ENSGGOG00000006302.3|UniProtKB=G3QTX8 G3QTX8 TLX2 PTHR45921:SF3 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009248.3|UniProtKB=G3RP79 G3RP79 PTHR22760:SF4 GLYCOSYLTRANSFERASE GPI ALPHA-1,2-MANNOSYLTRANSFERASE 3 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000009430.3|UniProtKB=A0A2I2YAL0 A0A2I2YAL0 MBNL1 PTHR12675:SF7 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000016512.3|UniProtKB=G3RK49 G3RK49 ENPP5 PTHR10151:SF125 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 5 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000011226.3|UniProtKB=G3R6J0 G3R6J0 GRK4 PTHR24355:SF14 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 GORGO|Ensembl=ENSGGOG00000025091.2|UniProtKB=G3S5D3 G3S5D3 ANAPC10 PTHR12936:SF6 ANAPHASE-PROMOTING COMPLEX 10 ANAPHASE-PROMOTING COMPLEX SUBUNIT 10 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cell cycle#GO:0007049;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;modification-dependent macromolecule catabolic process#GO:0043632 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Cell cycle#P00013>APC#P00481 GORGO|Ensembl=ENSGGOG00000013679.3|UniProtKB=A0A2I2ZR74 A0A2I2ZR74 SYT17 PTHR10024:SF348 SYNAPTOTAGMIN SYNAPTOTAGMIN-17 binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149;protein binding#GO:0005515;molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;vesicle-mediated transport#GO:0016192;transport#GO:0006810;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;localization#GO:0051179;regulation of secretion#GO:0051046 secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000002957.3|UniProtKB=G3QKD2 G3QKD2 BOLA1 PTHR46229:SF2 BOLA TRANSCRIPTION REGULATOR BOLA-LIKE PROTEIN 1 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000023648.2|UniProtKB=A0A2I2YEP0 A0A2I2YEP0 PTHR11071:SF469 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000002038.3|UniProtKB=G3QI14 G3QI14 LURAP1L PTHR33767:SF1 LEUCINE RICH ADAPTOR PROTEIN 1-LIKE LEUCINE RICH ADAPTOR PROTEIN 1-LIKE regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 GORGO|Ensembl=ENSGGOG00000004369.3|UniProtKB=G3QP01 G3QP01 MYF6 PTHR11534:SF4 MYOGENIC FACTOR MYOGENIC FACTOR 6 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;skeletal muscle tissue development#GO:0007519;positive regulation of cellular process#GO:0048522;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;muscle organ development#GO:0007517;positive regulation of cell differentiation#GO:0045597;striated muscle tissue development#GO:0014706;animal organ development#GO:0048513;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000002615.3|UniProtKB=G3QJI4 G3QJI4 USP5 PTHR24006:SF655 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5 cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000002205.3|UniProtKB=G3SEV1 G3SEV1 MFSD12 PTHR11328:SF50 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12 amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;neutral L-amino acid transmembrane transporter activity#GO:0015175;L-amino acid transmembrane transporter activity#GO:0015179 L-alpha-amino acid transmembrane transport#GO:1902475;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;carboxylic acid transmembrane transport#GO:1905039;pigmentation#GO:0043473;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;nitrogen compound transport#GO:0071705;regulation of metabolic process#GO:0019222;pigment metabolic process#GO:0042440;L-amino acid transport#GO:0015807;cellular process#GO:0009987;biological regulation#GO:0065007;metabolic process#GO:0008152;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000010997.3|UniProtKB=G3R5Z1 G3R5Z1 CAPRIN1 PTHR22922:SF3 GPI-ANCHORED PROTEIN P137 CAPRIN-1 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004777.3|UniProtKB=G3QQ26 G3QQ26 FYCO1 PTHR46753:SF2 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 organelle localization#GO:0051640;localization#GO:0051179;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810;regulation of autophagosome maturation#GO:1901096;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;regulation of catabolic process#GO:0009894;vesicle cytoskeletal trafficking#GO:0099518;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;positive regulation of macroautophagy#GO:0016239;microtubule-based process#GO:0007017;regulation of macroautophagy#GO:0016241;positive regulation of autophagy#GO:0010508;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650 intracellular organelle#GO:0043229;endosome#GO:0005768;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lytic vacuole#GO:0000323;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770 GORGO|Ensembl=ENSGGOG00000011050.3|UniProtKB=G3R641 G3R641 SEC24A PTHR13803:SF1 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24A cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;SNARE binding#GO:0000149;zinc ion binding#GO:0008270 cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vesicle coat#GO:0030120;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated membrane#GO:0048475 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000001765.3|UniProtKB=A0A2I2Z6Q0 A0A2I2Z6Q0 GRAMD4 PTHR37402:SF1 GRAM DOMAIN-CONTAINING PROTEIN 4 GRAM DOMAIN-CONTAINING PROTEIN 4 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of programmed cell death#GO:0043068;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;regulation of innate immune response#GO:0045088;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000005470.3|UniProtKB=G3QRU3 G3QRU3 HSPB9 PTHR47896:SF1 HEAT SHOCK PROTEIN BETA-9 HEAT SHOCK PROTEIN BETA-9 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000010063.3|UniProtKB=A0A2I2YK39 A0A2I2YK39 LOC101152949 PTHR11524:SF62 60S RIBOSOMAL PROTEIN L7 RIBOSOMAL PROTEIN L7 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014161.3|UniProtKB=G3RE48 G3RE48 NELFA PTHR13328:SF7 NEGATIVE ELONGATION FACTOR A NELF-A NEGATIVE ELONGATION FACTOR A regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000014621.3|UniProtKB=G3RF99 G3RF99 WBP1 PTHR16209:SF5 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN-BINDING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000038927.1|UniProtKB=A0A2I2ZWW5 A0A2I2ZWW5 PTHR22883:SF417 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC20 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;protein targeting#GO:0006605;developmental process#GO:0032502;protein targeting to membrane#GO:0006612;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;developmental maturation#GO:0021700 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000022054.2|UniProtKB=G3S4I3 G3S4I3 LOC101148834 PTHR11661:SF21 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11 RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025567.2|UniProtKB=G3RRH7 G3RRH7 OR4S2 PTHR26453:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003207.3|UniProtKB=G3QL13 G3QL13 PRKCD PTHR24356:SF365 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C DELTA TYPE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs(3)#P06850;Gonadotropin-releasing hormone receptor pathway#P06664>nPKCs#P06852;Apoptosis signaling pathway#P00006>PKCs#P00318;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;B cell activation#P00010>PKC#P00373;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Endothelin signaling pathway#P00019>PKC#P00568;CCKR signaling map#P06959>PKCdelta#P07134;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 GORGO|Ensembl=ENSGGOG00000012957.3|UniProtKB=G3RB06 G3RB06 MDM4 PTHR12183:SF37 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 PROTEIN MDM4 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;positive regulation of developmental process#GO:0051094;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mitochondrial fission#GO:0090140;regulation of developmental process#GO:0050793;regulation of mitochondrion organization#GO:0010821;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;regulation of protein stability#GO:0031647;regulation of anatomical structure morphogenesis#GO:0022603;protein stabilization#GO:0050821;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;positive regulation of mitochondrial fission#GO:0090141;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of organelle organization#GO:0010638;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;transcription regulator complex#GO:0005667;transcription repressor complex#GO:0017053 p53 pathway#P00059>Mdm2#P01483;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#G04674;P53 pathway feedback loops 1#P04392>Mdm2#P04536;P53 pathway feedback loops 1#P04392>MDM-2#G04682;p53 pathway feedback loops 2#P04398>MDM-2#G04709;p53 pathway feedback loops 2#P04398>Mdm2#P04663;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#P04496;p53 pathway#P00059>MDM-2#G01563 GORGO|Ensembl=ENSGGOG00000005330.3|UniProtKB=G3QRH0 G3QRH0 SP2 PTHR23235:SF1 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015157.3|UniProtKB=A0A2I2Z559 A0A2I2Z559 DET1 PTHR13374:SF3 DET1 HOMOLOG DE-ETIOLATED-1 HOMOLOG DET1 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;enzyme binding#GO:0019899;ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;ubiquitin-like protein ligase binding#GO:0044389;enzyme-substrate adaptor activity#GO:0140767;ubiquitin protein ligase binding#GO:0031625 regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;protein ubiquitination#GO:0016567;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;primary metabolic process#GO:0044238;protein modification process#GO:0036211;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000010123.3|UniProtKB=G3RM67 G3RM67 ERICH3 PTHR23034:SF2 GLUTAMATE-RICH PROTEIN 3 GLUTAMATE-RICH PROTEIN 3 GORGO|Ensembl=ENSGGOG00000042845.1|UniProtKB=A0A2I2YND0 A0A2I2YND0 KCNS1 PTHR11537:SF61 VOLTAGE-GATED POTASSIUM CHANNEL DELAYED-RECTIFIER POTASSIUM CHANNEL REGULATORY SUBUNIT KCNS1 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;action potential#GO:0001508;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transport#GO:0006813 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000007719.3|UniProtKB=G3QXK5 G3QXK5 CDCA8 PTHR16040:SF6 AUSTRALIN, ISOFORM A-RELATED BOREALIN mitotic cell cycle#GO:0000278;mitotic metaphase chromosome alignment#GO:0007080;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;localization#GO:0051179;organelle fission#GO:0048285;organelle localization#GO:0051640;nuclear division#GO:0000280;chromosome localization#GO:0050000;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310 organelle#GO:0043226;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;spindle midzone#GO:0051233;spindle#GO:0005819;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000039594.1|UniProtKB=G3QI35 G3QI35 LOC101136718 PTHR23262:SF208 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-1 multicellular organismal process#GO:0032501 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000025996.2|UniProtKB=G3S6T0 G3S6T0 SAPCD2 PTHR14907:SF3 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000011590.3|UniProtKB=A0A2I2YM31 A0A2I2YM31 SPATA31G1 PTHR21777:SF0 RCG55159-LIKE SPERMATOGENESIS-ASSOCIATED PROTEIN 31G1 GORGO|Ensembl=ENSGGOG00000027532.2|UniProtKB=G3S8Y8 G3S8Y8 MRPS21 PTHR21109:SF13 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013232.3|UniProtKB=G3RBQ2 G3RBQ2 CARS1 PTHR10890:SF33 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000023006.2|UniProtKB=A0A2I2ZMJ9 A0A2I2ZMJ9 CLP1 PTHR12755:SF6 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1 catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013186.3|UniProtKB=G3RBK8 G3RBK8 ARPC1B PTHR10709:SF10 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1B cortical actin cytoskeleton organization#GO:0030866;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912;Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876 GORGO|Ensembl=ENSGGOG00000007970.3|UniProtKB=G3QY64 G3QY64 DHRS11 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000000629.3|UniProtKB=G3SHA4 G3SHA4 EMP1 PTHR10671:SF6 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 1 cellular component organization or biogenesis#GO:0071840;bleb assembly#GO:0032060;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000022708.2|UniProtKB=G3SK76 G3SK76 THAP1 PTHR46600:SF14 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000001320.3|UniProtKB=G3QG55 G3QG55 ULK1 PTHR24348:SF19 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of cellular component size#GO:0032535;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;developmental growth involved in morphogenesis#GO:0060560;regulation of cell size#GO:0008361;autophagy#GO:0006914;response to stress#GO:0006950;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;regulation of cell growth#GO:0001558;plasma membrane bounded cell projection morphogenesis#GO:0120039;metabolic process#GO:0008152;cell projection morphogenesis#GO:0048858;regulation of axonogenesis#GO:0050770;cell growth#GO:0016049;regulation of growth#GO:0040008;response to starvation#GO:0042594;negative regulation of cellular component organization#GO:0051129;regulation of developmental process#GO:0050793;catabolic process#GO:0009056;organelle assembly#GO:0070925;system development#GO:0048731;vacuole organization#GO:0007033;regulation of nervous system development#GO:0051960;response to nutrient levels#GO:0031667;reticulophagy#GO:0061709;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cell growth#GO:0030308;macroautophagy#GO:0016236;developmental process#GO:0032502;autophagy of mitochondrion#GO:0000422;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;process utilizing autophagic mechanism#GO:0061919;neuron projection extension#GO:1990138;neuron development#GO:0048666;regulation of biological quality#GO:0065008;regulation of neuron projection development#GO:0010975;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;axon extension#GO:0048675;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;growth#GO:0040007;regulation of anatomical structure size#GO:0090066;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of multicellular organismal process#GO:0051241;regulation of neurogenesis#GO:0050767;developmental cell growth#GO:0048588;piecemeal microautophagy of the nucleus#GO:0034727;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of cell development#GO:0060284;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell differentiation#GO:0045595;neuron projection morphogenesis#GO:0048812;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;regulation of catabolic process#GO:0009894;regulation of plasma membrane bounded cell projection organization#GO:0120035;mitophagy#GO:0000423;developmental growth#GO:0048589 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;membrane#GO:0016020 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000027509.2|UniProtKB=G3RSA0 G3RSA0 GAS2 PTHR46756:SF9 TRANSGELIN GROWTH ARREST-SPECIFIC PROTEIN 2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000006036.3|UniProtKB=G3QTD2 G3QTD2 PRKDC PTHR11139:SF68 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 somatic cell DNA recombination#GO:0016444;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;macromolecule biosynthetic process#GO:0009059;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;apoptotic signaling pathway#GO:0097190;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;DNA damage response#GO:0006974;DNA repair#GO:0006281;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;somatic diversification of immune receptors#GO:0002200;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;system development#GO:0048731;telomere organization#GO:0032200;anatomical structure development#GO:0048856;cell communication#GO:0007154;gene expression#GO:0010467;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;double-strand break repair#GO:0006302;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;signaling#GO:0023052;production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896;V(D)J recombination#GO:0033151;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;immune system development#GO:0002520;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007217.3|UniProtKB=G3QWB4 G3QWB4 ATP2B3 PTHR24093:SF284 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 3 ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662 calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cytosolic calcium ion concentration#GO:0051480;homeostatic process#GO:0042592 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000039437.1|UniProtKB=G3RRH8 G3RRH8 ABT1 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000006413.3|UniProtKB=G3QU75 G3QU75 TAMALIN PTHR15963:SF3 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED PROTEIN TAMALIN regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular response to stimulus#GO:0051716;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell communication#GO:0007154;regulation of biological quality#GO:0065008;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879 membrane#GO:0016020;cell periphery#GO:0071944;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000008594.3|UniProtKB=G3RXM7 G3RXM7 SIX6 PTHR10390:SF12 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX6 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;sensory system development#GO:0048880;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;eye development#GO:0001654;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;visual system development#GO:0150063 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000044188.1|UniProtKB=A0A2I2YC90 A0A2I2YC90 CD302 PTHR22803:SF144 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED CD302 ANTIGEN membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000015028.3|UniProtKB=G3RVR3 G3RVR3 WARS2 PTHR43766:SF5 TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translation#GO:0006412;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000005501.3|UniProtKB=G3QRX4 G3QRX4 FBXO4 PTHR16008:SF4 F-BOX ONLY PROTEIN 4 F-BOX ONLY PROTEIN 4 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000011022.3|UniProtKB=G3R608 G3R608 E2F3 PTHR12081:SF44 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 p53 pathway feedback loops 2#P04398>E2F-1#P04652;p53 pathway#P00059>E2F-1#P04627;Cell cycle#P00013>E2F#P00488 GORGO|Ensembl=ENSGGOG00000011836.3|UniProtKB=G3R842 G3R842 TIGD4 PTHR19303:SF18 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000024767.2|UniProtKB=G3RY31 G3RY31 EN1 PTHR24341:SF4 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN ENGRAILED-1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 GORGO|Ensembl=ENSGGOG00000005600.3|UniProtKB=G3QS68 G3QS68 TG PTHR14093:SF19 HLA CLASS II GAMMA CHAIN THYROGLOBULIN regulation of biological quality#GO:0065008;metabolic process#GO:0008152;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;phenol-containing compound metabolic process#GO:0018958;modified amino acid metabolic process#GO:0006575 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000041194.1|UniProtKB=A0A2I2ZR86 A0A2I2ZR86 PTHR31796:SF3 SUZ DOMAIN-CONTAINING PROTEIN 1 SUZ-C DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000005684.3|UniProtKB=G3QSD4 G3QSD4 TMEM161B PTHR13624:SF3 RE42071P TRANSMEMBRANE PROTEIN 161B GORGO|Ensembl=ENSGGOG00000000406.3|UniProtKB=G3QDS2 G3QDS2 TRIM56 PTHR25462:SF299 BONUS, ISOFORM C-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM56 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 positive regulation of cytokine-mediated signaling pathway#GO:0001961;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of cytokine-mediated signaling pathway#GO:0001959;positive regulation of response to external stimulus#GO:0032103;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;regulation of response to cytokine stimulus#GO:0060759;response to biotic stimulus#GO:0009607;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of signal transduction#GO:0009967;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;positive regulation of cellular process#GO:0048522 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012830.3|UniProtKB=G3RAN7 G3RAN7 CCL28 PTHR12015:SF205 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 28 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000028470.2|UniProtKB=G3RMV3 G3RMV3 KCNH8 PTHR10217:SF380 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH8 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001288.3|UniProtKB=G3QG22 G3QG22 FCRLA PTHR11481:SF71 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE A molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;immune response#GO:0006955;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000038217.1|UniProtKB=A0A2I2ZF93 A0A2I2ZF93 MYADML2 PTHR17068:SF5 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER-LIKE PROTEIN 2 GORGO|Ensembl=ENSGGOG00000002550.3|UniProtKB=G3QJC1 G3QJC1 GOT1 PTHR11879:SF3 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 GORGO|Ensembl=ENSGGOG00000008066.2|UniProtKB=G3QYE9 G3QYE9 LOC101144401 PTHR23430:SF199 HISTONE H2A HISTONE H2AX structural molecule activity#GO:0005198 cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000038402.1|UniProtKB=A0A2I2YXB8 A0A2I2YXB8 UCK2 PTHR10285:SF131 URIDINE KINASE URIDINE-CYTIDINE KINASE 2 nucleoside kinase activity#GO:0019206;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149 GORGO|Ensembl=ENSGGOG00000006005.3|UniProtKB=G3QT66 G3QT66 NFKBIL1 PTHR15263:SF2 I-KAPPA-B-LIKE PROTEIN IKBL NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 regulation of canonical NF-kappaB signal transduction#GO:0043122;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 B cell activation#P00010>I kappa B#P00392 GORGO|Ensembl=ENSGGOG00000042949.1|UniProtKB=A0A2I2YJR3 A0A2I2YJR3 FHIT PTHR46981:SF1 BIS(5'-ADENOSYL)-TRIPHOSPHATASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE ubiquitin protein ligase binding#GO:0031625;pyrophosphatase activity#GO:0016462;ubiquitin-like protein ligase binding#GO:0044389;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;enzyme binding#GO:0019899 regulation of cellular process#GO:0050794;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nucleoside phosphate metabolic process#GO:0006753;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteasomal protein catabolic process#GO:1901799;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;cell communication#GO:0007154;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;organophosphate catabolic process#GO:0046434;regulation of protein catabolic process#GO:0042176;intracellular signal transduction#GO:0035556;negative regulation of catabolic process#GO:0009895;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;organophosphate metabolic process#GO:0019637;negative regulation of macromolecule metabolic process#GO:0010605;apoptotic signaling pathway#GO:0097190;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;nucleotide catabolic process#GO:0009166;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;small molecule metabolic process#GO:0044281;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;purine-containing compound metabolic process#GO:0072521;apoptotic process#GO:0006915;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;nucleotide metabolic process#GO:0009117;signal transduction by p53 class mediator#GO:0072331;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein catabolic process#GO:0042177;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;nucleobase-containing small molecule metabolic process#GO:0055086;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000004122.3|UniProtKB=A0A2I2ZP50 A0A2I2ZP50 KMT5B PTHR12977:SF12 SUPPRESSOR OF VARIEGATION 4-20-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000012457.3|UniProtKB=G3R9R6 G3R9R6 LOC101134111 PTHR24027:SF290 CADHERIN-23 CADHERIN-10 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell junction organization#GO:0034330;cell motility#GO:0048870;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;synaptic membrane adhesion#GO:0099560;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;synapse organization#GO:0050808;cell migration#GO:0016477;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000003333.3|UniProtKB=G3QLC9 G3QLC9 TERB1 PTHR14014:SF0 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;homologous chromosome pairing at meiosis#GO:0007129;chromosome localization#GO:0050000;sexual reproduction#GO:0019953;nuclear division#GO:0000280;organelle localization#GO:0051640;telomere tethering at nuclear periphery#GO:0034398;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;localization#GO:0051179;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;telomere localization#GO:0034397;cell cycle#GO:0007049;reproductive process#GO:0022414 GORGO|Ensembl=ENSGGOG00000013392.3|UniProtKB=G3RC41 G3RC41 PDCL PTHR46052:SF4 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN-LIKE PROTEIN protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000013629.3|UniProtKB=G3RCR0 G3RCR0 LOC101144371 PTHR14224:SF86 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 SUBFAMILY NOT NAMED enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462 GORGO|Ensembl=ENSGGOG00000022998.2|UniProtKB=A0A2I2Y9B2 A0A2I2Y9B2 OSER1 PTHR31383:SF2 OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 1 OXIDATIVE STRESS-RESPONSIVE SERINE-RICH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000010953.3|UniProtKB=G3R5U0 G3R5U0 PSMB8 PTHR11599:SF53 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-8 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012132.3|UniProtKB=A0A2I2ZL58 A0A2I2ZL58 STIP1 PTHR22904:SF517 TPR REPEAT CONTAINING PROTEIN STRESS-INDUCED-PHOSPHOPROTEIN 1 heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;binding#GO:0005488;protein binding#GO:0005515 GORGO|Ensembl=ENSGGOG00000015565.3|UniProtKB=G3RHQ6 G3RHQ6 N4BP1 PTHR12876:SF26 N4BP1-RELATED NEDD4-BINDING PROTEIN 1 nuclease activity#GO:0004518;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of protein modification process#GO:0031399;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of protein ubiquitination#GO:0031396;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;positive regulation of RNA metabolic process#GO:0051254;negative regulation of proteasomal protein catabolic process#GO:1901799;positive regulation of mRNA catabolic process#GO:0061014;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of RNA metabolic process#GO:0051252;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;regulation of RNA stability#GO:0043487;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of protein catabolic process#GO:0042177;regulation of protein metabolic process#GO:0051246;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of protein ubiquitination#GO:0031397 cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000005064.3|UniProtKB=G3QQT9 G3QQT9 GSTO1 PTHR43968:SF5 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA-1 oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;transferase activity#GO:0016740;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 L-ascorbic acid metabolic process#GO:0019852;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;glutathione metabolic process#GO:0006749;monosaccharide metabolic process#GO:0005996;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000037287.1|UniProtKB=G3QRE0 G3QRE0 ZNF551 PTHR24381:SF476 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 819 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000012496.3|UniProtKB=G3RNQ9 G3RNQ9 GCGR PTHR45620:SF29 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013996.3|UniProtKB=G3RDN8 G3RDN8 JPT1 PTHR34930:SF9 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 1 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000025400.2|UniProtKB=G3S594 G3S594 ISM2 PTHR10239:SF28 ISTHMIN-2 ISTHMIN-2 GORGO|Ensembl=ENSGGOG00000026368.2|UniProtKB=G3SFT8 G3SFT8 PTHR23268:SF122 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 4-2 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000014661.3|UniProtKB=G3RFD9 G3RFD9 GPX7 PTHR11592:SF5 GLUTATHIONE PEROXIDASE PROTEIN PEROXIDASE GPX7 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000004361.3|UniProtKB=G3QNZ8 G3QNZ8 HAO1 PTHR10578:SF151 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058;cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000008680.3|UniProtKB=G3R007 G3R007 S100A11 PTHR11639:SF60 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A11 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000000974.3|UniProtKB=A0A2I2Z0C0 A0A2I2Z0C0 MAP7 PTHR15073:SF4 MICROTUBULE-ASSOCIATED PROTEIN ENSCONSIN regulation of microtubule-based process#GO:0032886;microtubule bundle formation#GO:0001578;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000001847.3|UniProtKB=G3QHJ2 G3QHJ2 TEAD3 PTHR11834:SF7 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-5 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;hippo signaling#GO:0035329;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000010706.3|UniProtKB=G3R567 G3R567 KCTD6 PTHR14499:SF149 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein binding#GO:0005515 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022775.2|UniProtKB=G3RX24 G3RX24 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of cellular process#GO:0050794;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of protein stability#GO:0031647 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000026169.2|UniProtKB=A0A2I2Y311 A0A2I2Y311 KLRF1 PTHR46746:SF7 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY F MEMBER 2 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY F MEMBER 1 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006376.3|UniProtKB=G3QU40 G3QU40 TEKTL1 PTHR35081:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 105 TEKTIN-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000000346.3|UniProtKB=G3QDL5 G3QDL5 GPBP1L1 PTHR14339:SF10 VASCULIN VASCULIN-LIKE PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000024653.2|UniProtKB=G3SAF5 G3SAF5 PTHR10286:SF57 INORGANIC PYROPHOSPHATASE INORGANIC PYROPHOSPHATASE hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 metabolic process#GO:0008152;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 pyrophosphatase#PC00196 GORGO|Ensembl=ENSGGOG00000043835.1|UniProtKB=A0A2I2ZB36 A0A2I2ZB36 PTHR10072:SF63 IRON-SULFUR CLUSTER ASSEMBLY PROTEIN IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 biosynthetic process#GO:0009058;iron-sulfur cluster assembly#GO:0016226;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular component biogenesis#GO:0044085;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000043178.1|UniProtKB=A0A2I2ZDZ2 A0A2I2ZDZ2 PTHR20648:SF13 ELONGIN-C ELONGIN-C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000005160.3|UniProtKB=G3QR25 G3QR25 THOC6 PTHR44411:SF1 THO COMPLEX SUBUNIT 6 HOMOLOG THO COMPLEX SUBUNIT 6 transport#GO:0006810;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658 intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;transcription export complex#GO:0000346 GORGO|Ensembl=ENSGGOG00000010155.3|UniProtKB=G3R3T1 G3R3T1 FUZ PTHR13559:SF1 INTRACELLULAR TRAFFIC PROTEIN-RELATED PROTEIN FUZZY HOMOLOG cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 GORGO|Ensembl=ENSGGOG00000038397.1|UniProtKB=A0A2I2YXZ9 A0A2I2YXZ9 PTHR22812:SF134 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 3 binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;heterochromatin#GO:0000792 GORGO|Gene=CXCR2|UniProtKB=Q28422 Q28422 CXCR2 PTHR10489:SF689 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 2 immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;intracellular signaling cassette#GO:0141124;neutrophil migration#GO:1990266;response to chemical#GO:0042221;taxis#GO:0042330;granulocyte migration#GO:0097530;signal transduction#GO:0007165;cellular process#GO:0009987;neutrophil chemotaxis#GO:0030593;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;chemotaxis#GO:0006935;biological regulation#GO:0065007;cell migration#GO:0016477;immune response#GO:0006955;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;calcium-mediated signaling#GO:0019722;leukocyte chemotaxis#GO:0030595;leukocyte migration#GO:0050900 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 cell adhesion molecule#PC00069 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000010508.3|UniProtKB=A0A2I2ZRU3 A0A2I2ZRU3 PRKD2 PTHR22968:SF12 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE D2 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;EGF receptor signaling pathway#P00018>PKC#P00565;CCKR signaling map#P06959>PRKD2#P07216 GORGO|Ensembl=ENSGGOG00000015704.3|UniProtKB=G3RI30 G3RI30 REM2 PTHR45775:SF5 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN REM 2 transporter regulator activity#GO:0141108;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;calcium channel regulator activity#GO:0005246;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010566.3|UniProtKB=G3R4U5 G3R4U5 FAM204A PTHR14386:SF2 PROTEIN FAM204A PROTEIN FAM204A GORGO|Ensembl=ENSGGOG00000014782.3|UniProtKB=G3RFP7 G3RFP7 NKG7 PTHR10671:SF34 EPITHELIAL MEMBRANE PROTEIN-RELATED PROTEIN NKG7 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000010662.3|UniProtKB=G3R538 G3R538 CAT PTHR11465:SF9 CATALASE CATALASE binding#GO:0005488;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to oxygen-containing compound#GO:1901700;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302;response to stress#GO:0006950;cellular process#GO:0009987;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to chemical#GO:0042221;hydrogen peroxide metabolic process#GO:0042743 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 peroxidase#PC00180 GORGO|Ensembl=ENSGGOG00000022610.2|UniProtKB=G3RVL3 G3RVL3 PTHR16717:SF2 CYTOCHROME C OXIDASE POLYPEPTIDE VIII CYTOCHROME C OXIDASE SUBUNIT 8C, MITOCHONDRIAL membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transporter complex#GO:1990351 metabolite interconversion enzyme#PC00262;oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000028324.2|UniProtKB=G3S749 G3S749 GPR119 PTHR22750:SF7 G-PROTEIN COUPLED RECEPTOR GLUCOSE-DEPENDENT INSULINOTROPIC RECEPTOR phospholipid binding#GO:0005543;G protein-coupled receptor activity#GO:0004930;phosphatidylcholine binding#GO:0031210;signaling receptor activity#GO:0038023;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;cation binding#GO:0043169 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000027289.2|UniProtKB=A0A2I2Y4M0 A0A2I2Y4M0 ADGRE3 PTHR12011:SF455 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E3 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000001018.3|UniProtKB=G3QFD5 G3QFD5 AACS PTHR42921:SF5 ACETOACETYL-COA SYNTHETASE ACETOACETYL-COA SYNTHETASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 biological regulation#GO:0065007;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;regulation of insulin secretion#GO:0050796;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of protein secretion#GO:0050714;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of hormone levels#GO:0010817;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;positive regulation of signaling#GO:0023056;regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;regulation of signaling#GO:0023051;positive regulation of hormone secretion#GO:0046887;positive regulation of secretion#GO:0051047 metabolite interconversion enzyme#PC00262;ligase#PC00142 GORGO|Ensembl=ENSGGOG00000000817.3|UniProtKB=A0A2I2Z676 A0A2I2Z676 KSR1 PTHR23257:SF716 SERINE-THREONINE PROTEIN KINASE KINASE SUPPRESSOR OF RAS 1 protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>KSR-1#P06842 GORGO|Ensembl=ENSGGOG00000026474.2|UniProtKB=A0A2I2Y3W9 A0A2I2Y3W9 PTHR24393:SF145 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 780B sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013013.3|UniProtKB=G3RB62 G3RB62 TMC4 PTHR23302:SF45 TRANSMEMBRANE CHANNEL-RELATED VOLTAGE-GATED CHLORIDE CHANNEL TMC4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic anion channel activity#GO:0008308;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000016367.3|UniProtKB=A0A2I2Z250 A0A2I2Z250 TEAD2 PTHR11834:SF5 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;hippo signaling#GO:0035329;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000014667.3|UniProtKB=A0A2I2ZSG9 A0A2I2ZSG9 ABCG1 PTHR48041:SF90 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 1 ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;transmembrane transport#GO:0055085;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;transport#GO:0006810;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;sterol transport#GO:0015918;cellular process#GO:0009987;cholesterol efflux#GO:0033344;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000000498.3|UniProtKB=G3RX09 G3RX09 RNASET2 PTHR11240:SF94 RIBONUCLEASE T2 RIBONUCLEASE T2 endonuclease activity#GO:0004519;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 RNA catabolic process#GO:0006401;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000002793.3|UniProtKB=G3QJZ1 G3QJZ1 KRT84 PTHR45616:SF17 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CUTICULAR HB4 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelium development#GO:0060429;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;developmental process#GO:0032502;epidermis development#GO:0008544;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000022237.2|UniProtKB=G3SG26 G3SG26 PTHR11081:SF55 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE 1 catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;magnesium ion binding#GO:0000287;cation binding#GO:0043169;catalytic activity, acting on DNA#GO:0140097;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;exonuclease activity#GO:0004527;metal ion binding#GO:0046872;DNA endonuclease activity#GO:0004520;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;DNA replication#GO:0006260;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000006327.3|UniProtKB=G3QU02 G3QU02 HTRA2 PTHR22939:SF127 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA2, MITOCHONDRIAL catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;proteolysis#GO:0006508 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000007206.3|UniProtKB=G3QWD4 G3QWD4 DNAH5 PTHR46532:SF13 MALE FERTILITY FACTOR KL5 DYNEIN AXONEMAL HEAVY CHAIN 5 GORGO|Ensembl=ENSGGOG00000024581.2|UniProtKB=G3RNX7 G3RNX7 LOC101141792 PTHR13337:SF6 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL heme binding#GO:0020037;binding#GO:0005488;small molecule binding#GO:0036094;tetrapyrrole binding#GO:0046906 primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060 respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000002986.3|UniProtKB=A0A2I2YMS4 A0A2I2YMS4 TMEM41B PTHR43220:SF18 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41B process utilizing autophagic mechanism#GO:0061919;autophagosome assembly#GO:0000045;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;organelle assembly#GO:0070925;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000036734.1|UniProtKB=A0A2I2YRA4 A0A2I2YRA4 PTHR45723:SF1 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;preribosome#GO:0030684;cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000005087.3|UniProtKB=G3QQW1 G3QQW1 FAM171A1 PTHR31626:SF1 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171A1 actin filament bundle assembly#GO:0051017;regulation of biological process#GO:0050789;actin filament bundle organization#GO:0061572;regulation of cell shape#GO:0008360;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;regulation of biological quality#GO:0065008;stress fiber assembly#GO:0043149;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;contractile actin filament bundle assembly#GO:0030038;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000015215.3|UniProtKB=G3RGT7 G3RGT7 DNHD1 PTHR10676:SF359 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN DOMAIN-CONTAINING PROTEIN 1 polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;microtubule-based movement#GO:0007018;cell motility#GO:0048870 dynein complex#GO:0030286;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000026416.2|UniProtKB=G3S344 G3S344 INTS15 PTHR14540:SF2 INTEGRATOR COMPLEX SUBUNIT 15 INTEGRATOR COMPLEX SUBUNIT 15 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;integrator complex#GO:0032039;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000026239.2|UniProtKB=A0A2I2YW17 A0A2I2YW17 SNX4 PTHR46596:SF1 SORTING NEXIN-4 SORTING NEXIN-4 phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289 regulation of catabolic process#GO:0009894;regulation of macroautophagy#GO:0016241;intracellular protein localization#GO:0008104;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;establishment of protein localization#GO:0045184;regulation of organelle assembly#GO:1902115;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;positive regulation of autophagy#GO:0010508;protein transport#GO:0015031;positive regulation of organelle organization#GO:0010638;localization#GO:0051179;positive regulation of metabolic process#GO:0009893;positive regulation of cellular component organization#GO:0051130;regulation of autophagosome assembly#GO:2000785;regulation of cellular component biogenesis#GO:0044087;positive regulation of macroautophagy#GO:0016239;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506 cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;early endosome membrane#GO:0031901;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;organelle#GO:0043226;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008548.3|UniProtKB=G3QZP4 G3QZP4 NAPB PTHR13768:SF12 SOLUBLE NSF ATTACHMENT PROTEIN SNAP BETA-SOLUBLE NSF ATTACHMENT PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;cellular localization#GO:0051641;cellular component disassembly#GO:0022411;protein transport#GO:0015031;synaptic signaling#GO:0099536;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;synaptic transmission, glutamatergic#GO:0035249;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;protein-containing complex disassembly#GO:0032984;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;localization#GO:0051179;macromolecule localization#GO:0033036;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 neuron projection#GO:0043005;presynapse#GO:0098793;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;cell junction#GO:0030054;membrane protein complex#GO:0098796;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell projection#GO:0042995;neuron projection terminus#GO:0044306;synapse#GO:0045202;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;axon#GO:0030424;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005157.3|UniProtKB=G3QR18 G3QR18 HCFC1R1 PTHR16246:SF2 HOST CELL FACTOR C1 REGULATOR 1 HOST CELL FACTOR C1 REGULATOR 1 GORGO|Ensembl=ENSGGOG00000008554.3|UniProtKB=G3RVY3 G3RVY3 GPRASP2 PTHR46414:SF1 PROTEIN BHLHB9-RELATED G PROTEIN-COUPLED RECEPTOR-ASSOCIATED SORTING PROTEIN 2 G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000006846.3|UniProtKB=G3QVD5 G3QVD5 MUC21 PTHR39408:SF4 MUCIN-21 MUCIN-21 negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;regulation of cell-cell adhesion#GO:0022407;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000002371.3|UniProtKB=G3QIW3 G3QIW3 SLURP1 PTHR10036:SF17 CD59 GLYCOPROTEIN SECRETED LY-6_UPAR-RELATED PROTEIN 1 acetylcholine receptor regulator activity#GO:0030548;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;neurotransmitter receptor regulator activity#GO:0099602 GORGO|Ensembl=ENSGGOG00000028463.2|UniProtKB=A0A2I2YSE4 A0A2I2YSE4 TCAF1 PTHR15730:SF1 EXPERIMENTAL AUTOIMMUNE PROSTATITIS ANTIGEN 2-RELATED TRPM8 CHANNEL-ASSOCIATED FACTOR 1 protein binding#GO:0005515;binding#GO:0005488;transmembrane transporter binding#GO:0044325 regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of establishment of protein localization#GO:0070201;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016024.3|UniProtKB=G3RIY5 G3RIY5 OTOG PTHR11339:SF228 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED OTOGELIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000027054.2|UniProtKB=A0A2I2YFC8 A0A2I2YFC8 PTHR12138:SF166 PRIMATE-EXPANDED PROTEIN FAMILY C2H2-TYPE DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000008297.3|UniProtKB=G3QZ13 G3QZ13 CFAP77 PTHR28617:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000012301.3|UniProtKB=G3R9C4 G3R9C4 RBP1 PTHR11955:SF56 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 1 small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289;alcohol binding#GO:0043178 lipid transport#GO:0006869;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000006210.3|UniProtKB=G3QTP0 G3QTP0 C1H1orf74 PTHR31366:SF2 UPF0739 PROTEIN C1ORF74 UPF0739 PROTEIN C1ORF74 GORGO|Ensembl=ENSGGOG00000006755.3|UniProtKB=G3QV43 G3QV43 LOC101153273 PTHR26453:SF654 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013624.3|UniProtKB=G3RCQ3 G3RCQ3 PRAMEF12 PTHR14224:SF111 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 12 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462 GORGO|Ensembl=ENSGGOG00000017004.3|UniProtKB=G3RLF1 G3RLF1 LOC101136413 PTHR48001:SF135 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1N2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014007.3|UniProtKB=G3RDQ8 G3RDQ8 TRMT1 PTHR10631:SF14 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000004218.3|UniProtKB=G3SFF9 G3SFF9 GGA2 PTHR45905:SF2 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA2 small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;intracellular protein localization#GO:0008104;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport to the plasma membrane#GO:0098876;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;macromolecule localization#GO:0033036;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 GORGO|Ensembl=ENSGGOG00000039492.1|UniProtKB=A0A2I2ZM60 A0A2I2ZM60 PTHR11743:SF81 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL NON-SELECTIVE VOLTAGE-GATED ION CHANNEL VDAC1 gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308 mitochondrial transport#GO:0006839;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular localization#GO:0051641;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle outer membrane#GO:0031968;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;cell periphery#GO:0071944 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000008762.3|UniProtKB=G3R090 G3R090 MRTFB PTHR22793:SF5 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN-RELATED TRANSCRIPTION FACTOR B muscle structure development#GO:0061061;cell differentiation#GO:0030154;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000042037.1|UniProtKB=A0A2I2ZJW0 A0A2I2ZJW0 PTHR13313:SF2 CYTOCHROME C OXIDASE SUBUNIT VIIC CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transporter complex#GO:1990351 oxidoreductase#PC00176;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000012733.3|UniProtKB=G3RAD9 G3RAD9 SF1 PTHR11468:SF32 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, MUSCLE FORM hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 generation of precursor metabolites and energy#GO:0006091;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;glycogen catabolic process#GO:0005980;energy reserve metabolic process#GO:0006112;carbohydrate catabolic process#GO:0016052;polysaccharide catabolic process#GO:0000272;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;glycogen metabolic process#GO:0005977;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 glycosyltransferase#PC00111;transferase#PC00220 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 GORGO|Ensembl=ENSGGOG00000003216.3|UniProtKB=G3QL18 G3QL18 LOC101143886 PTHR11528:SF100 HEAT SHOCK PROTEIN 90 FAMILY MEMBER ENDOPLASMIN nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;ATP-dependent activity#GO:0140657 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;protein folding#GO:0006457;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 chaperone#PC00072;Hsp90 family chaperone#PC00028 GORGO|Ensembl=ENSGGOG00000015654.3|UniProtKB=G3RHZ3 G3RHZ3 SERPING1 PTHR11461:SF159 SERINE PROTEASE INHIBITOR, SERPIN PLASMA PROTEASE C1 INHIBITOR enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000044027.1|UniProtKB=A0A2I2Z0K3 A0A2I2Z0K3 KRTAP10-7 PTHR23262:SF227 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-7 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000015655.3|UniProtKB=G3RHZ4 G3RHZ4 RAB27B PTHR47977:SF33 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-27B GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 regulation of cellular process#GO:0050794;export from cell#GO:0140352;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of secretion#GO:0051046;secretion#GO:0046903;secretion by cell#GO:0032940;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;positive regulation of secretion#GO:0051047;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of transport#GO:0051049;exocytosis#GO:0006887;regulation of localization#GO:0032879;transport#GO:0006810 endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;Golgi apparatus#GO:0005794;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;apical plasma membrane#GO:0016324;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000001473.3|UniProtKB=G3S3A8 G3S3A8 TYW1 PTHR13930:SF0 S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 lyase#PC00144 GORGO|Ensembl=ENSGGOG00000013550.3|UniProtKB=G3RCJ8 G3RCJ8 ZNF335 PTHR24403:SF36 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 335 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;animal gross anatomical part developmental process#GO:0160108;central nervous system development#GO:0007417;positive regulation of nervous system development#GO:0051962;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of cell differentiation#GO:0045597;head development#GO:0060322;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000000225.3|UniProtKB=G3QDB1 G3QDB1 GDF7 PTHR11848:SF160 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 7 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;kidney development#GO:0001822;renal system development#GO:0072001;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000001080.3|UniProtKB=G3QFJ0 G3QFJ0 ADH6 PTHR43880:SF20 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE 6 all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;cation binding#GO:0043169;metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to chemical#GO:0042221;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;regulation of biological quality#GO:0065008;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;small molecule catabolic process#GO:0044282;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;regulation of hormone levels#GO:0010817;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular detoxification of aldehyde#GO:0110095;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;aldehyde catabolic process#GO:0046185;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;response to toxic substance#GO:0009636;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000014744.3|UniProtKB=A0A2I2YVZ0 A0A2I2YVZ0 GTPBP2 PTHR43721:SF3 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 2 translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000000204.3|UniProtKB=G3QD91 G3QD91 MAOB PTHR43563:SF24 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] B catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 amine catabolic process#GO:0009310;metabolic process#GO:0008152;serotonin metabolic process#GO:0042428;phenol-containing compound metabolic process#GO:0018958;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidase#PC00175;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401;Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067;Dopamine receptor mediated signaling pathway#P05912>MAO#P05963 GORGO|Ensembl=ENSGGOG00000013664.3|UniProtKB=G3RCT7 G3RCT7 ZFP82 PTHR24377:SF940 IP01015P-RELATED ZINC FINGER PROTEIN 14 HOMOLOG RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000027097.2|UniProtKB=G3RMX5 G3RMX5 LOC101134642 PTHR12988:SF6 SPHINGOMYELIN PHOSPHODIESTERASE 4 SPHINGOMYELIN PHOSPHODIESTERASE 4 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;lipase activity#GO:0016298;catalytic activity#GO:0003824 phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;sphingolipid catabolic process#GO:0030149;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;organophosphate catabolic process#GO:0046434;glycerolipid catabolic process#GO:0046503;lipid biosynthetic process#GO:0008610;sphingomyelin metabolic process#GO:0006684;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513 phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000008460.3|UniProtKB=G3RT05 G3RT05 GHAA PTHR23239:SF348 INTERMEDIATE FILAMENT KERATIN 41 structural molecule activity#GO:0005198 intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;organelle organization#GO:0006996;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000014134.3|UniProtKB=G3RE28 G3RE28 CEP89 PTHR36170:SF1 CENTROSOMAL PROTEIN OF 89 KDA CENTROSOMAL PROTEIN OF 89 KDA cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary transition fiber#GO:0097539;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010278.3|UniProtKB=G3R450 G3R450 ZC3H14 PTHR14738:SF29 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;binding#GO:0005488;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143 post-transcriptional regulation of gene expression#GO:0010608;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA stability#GO:0043488 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000037099.1|UniProtKB=A0A2I2Y814 A0A2I2Y814 IRS1 PTHR10614:SF11 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 1 signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901 cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;response to peptide hormone#GO:0043434;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to hormone#GO:0009725;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;insulin-like growth factor receptor signaling pathway#GO:0048009;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>IRS-1#P06825;PI3 kinase pathway#P00048>IRS#P01193;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899;CCKR signaling map#P06959>IRS1#P07106;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Interleukin signaling pathway#P00036>IRS1/2#P00980;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759 GORGO|Ensembl=ENSGGOG00000028511.2|UniProtKB=G3SFJ8 G3SFJ8 DR1 PTHR46138:SF1 PROTEIN DR1 PROTEIN DR1 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000007340.3|UniProtKB=G3QWM6 G3QWM6 IARS2 PTHR42765:SF3 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000039295.1|UniProtKB=A0A2I2YD98 A0A2I2YD98 OSTN PTHR35353:SF1 OSTEOCRIN OSTEOCRIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003678.3|UniProtKB=G3SGG8 G3SGG8 ELAVL2 PTHR10352:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 2 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000001719.3|UniProtKB=G3QH70 G3QH70 GBP2 PTHR10751:SF112 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 2 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme inhibitor activity#GO:0004857;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;endopeptidase inhibitor activity#GO:0004866 response to other organism#GO:0051707;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;antiviral innate immune response#GO:0140374;defense response to virus#GO:0051607;response to virus#GO:0009615;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 heterotrimeric G-protein#PC00117;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000042880.1|UniProtKB=A0A2I2YNW8 A0A2I2YNW8 GMPR PTHR43170:SF4 GMP REDUCTASE GMP REDUCTASE 2 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000001361.3|UniProtKB=G3QG93 G3QG93 C2H3orf20 PTHR23093:SF20 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 20 GORGO|Ensembl=ENSGGOG00000008343.3|UniProtKB=G3QZ53 G3QZ53 BIRC7 PTHR10044:SF163 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7 enzyme regulator activity#GO:0030234;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;positive regulation of protein ubiquitination#GO:0031398;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000010064.3|UniProtKB=A0A2I2YZM6 A0A2I2YZM6 SYCP2 PTHR15607:SF12 SYNAPTONEMAL COMPLEX PROTEIN-RELATED SYNAPTONEMAL COMPLEX PROTEIN 2 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;condensed chromosome, centromeric region#GO:0000779;synaptonemal structure#GO:0099086;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000023352.2|UniProtKB=A0A2I2ZM87 A0A2I2ZM87 PTHR13337:SF10 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT heme binding#GO:0020037;small molecule binding#GO:0036094;binding#GO:0005488;tetrapyrrole binding#GO:0046906 aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;electron transport chain#GO:0022900 respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000043947.1|UniProtKB=A0A2I2YC20 A0A2I2YC20 PTHR19367:SF8 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 3 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000007906.4|UniProtKB=G3QY21 G3QY21 PHF3 PTHR11477:SF10 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN PHD FINGER PROTEIN 3 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003541.3|UniProtKB=G3QLV8 G3QLV8 ZNF582 PTHR24381:SF115 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 582 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000041597.1|UniProtKB=A0A2I2Y569 A0A2I2Y569 C18H16orf87 PTHR31101:SF3 UPF0547 PROTEIN C16ORF87 UPF0547 PROTEIN C16ORF87 GORGO|Ensembl=ENSGGOG00000037457.1|UniProtKB=A0A2I2ZXJ3 A0A2I2ZXJ3 PTHR23281:SF41 MERLIN/MOESIN/EZRIN/RADIXIN FERM DOMAIN-CONTAINING PROTEIN actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 regulation of anatomical structure morphogenesis#GO:0022603;regulation of transport#GO:0051049;regulation of localization#GO:0032879;biological regulation#GO:0065007;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;filopodium#GO:0030175;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000002779.3|UniProtKB=Q8SQ13 Q8SQ13 RNASE1 PTHR11437:SF24 RIBONUCLEASE RIBONUCLEASE PANCREATIC catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540 defense response#GO:0006952;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000010663.3|UniProtKB=G3R534 G3R534 NSMCE4A PTHR16140:SF2 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 HOMOLOG A macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000005970.3|UniProtKB=G3QT32 G3QT32 KLRB1 PTHR46784:SF1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of natural killer cell mediated immunity#GO:0002715;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of cell killing#GO:0031341;regulation of immune effector process#GO:0002697;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of natural killer cell mediated cytotoxicity#GO:0042269;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002547.3|UniProtKB=A0A2I2YG28 A0A2I2YG28 NEK11 PTHR43671:SF111 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK11 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cellular response to stress#GO:0033554;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of cell cycle#GO:0045786;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic cell cycle process#GO:1903047;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA integrity checkpoint signaling#GO:0031570 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008212.3|UniProtKB=G3QYT5 G3QYT5 SOD2 PTHR11404:SF42 SUPEROXIDE DISMUTASE 2 SUPEROXIDE DISMUTASE catalytic activity#GO:0003824;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000039908.1|UniProtKB=A0A2I2Y1X5 A0A2I2Y1X5 PTHR18860:SF78 14-3-3 PROTEIN 14-3-3 DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488 regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026900.2|UniProtKB=A0A2I2YJJ3 A0A2I2YJJ3 CYYR1 PTHR38490:SF1 CYSTEINE AND TYROSINE-RICH PROTEIN 1 CYSTEINE AND TYROSINE-RICH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000000681.3|UniProtKB=G3QEH6 G3QEH6 SELENOK PTHR16875:SF0 SELENOPROTEIN K SELENOPROTEIN K intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;regulation of response to stimulus#GO:0048583;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;regulation of signaling#GO:0023051;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;regulation of intracellular signal transduction#GO:1902531;regulation of calcium-mediated signaling#GO:0050848;homeostatic process#GO:0042592;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000041705.1|UniProtKB=A0A2I2ZNS2 A0A2I2ZNS2 ZNF48 PTHR24376:SF239 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 48 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000011352.3|UniProtKB=G3R6U6 G3R6U6 ZFP28 PTHR23226:SF321 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZFP28 ZINC FINGER PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003537.3|UniProtKB=A0A2I2YC34 A0A2I2YC34 ADGRD1 PTHR12011:SF216 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR D1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004379.3|UniProtKB=A0A2I2ZPT5 A0A2I2ZPT5 SLC18A2 PTHR23506:SF30 GH10249P SYNAPTIC VESICULAR AMINE TRANSPORTER solute:sodium symporter activity#GO:0015370;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215 vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;localization#GO:0051179;synaptic vesicle cycle#GO:0099504;transport#GO:0006810 intracellular vesicle#GO:0097708;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;secretory vesicle#GO:0099503;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;organelle membrane#GO:0031090;axon terminus#GO:0043679 secondary carrier transporter#PC00258;transporter#PC00227 5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410;CCKR signaling map#P06959>VMAT2#G07295;Dopamine receptor mediated signaling pathway#P05912>VAT2#P05960;Nicotine pharmacodynamics pathway#P06587>SLC18A2#P06604;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424;CCKR signaling map#P06959>VMAT2#P07137;CCKR signaling map#P06959>VMAT2#G07002;Adrenaline and noradrenaline biosynthesis#P00001>VAT2#P00070;Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071 GORGO|Ensembl=ENSGGOG00000012726.3|UniProtKB=G3RAE3 G3RAE3 FAM83G PTHR16181:SF39 PROTEIN FAM83A-RELATED PROTEIN FAM83G enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 GORGO|Gene=HBA|UniProtKB=P01923 P01923 HBA PTHR11442:SF48 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ALPHA tetrapyrrole binding#GO:0046906;molecular carrier activity#GO:0140104;binding#GO:0005488;heme binding#GO:0020037 homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;localization#GO:0051179;cell development#GO:0048468;homeostatic process#GO:0042592;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;cellular process#GO:0009987;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 globin#PC00107;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000003369.3|UniProtKB=A0A2I2YNI2 A0A2I2YNI2 LASP1 PTHR46218:SF2 LASP LIM AND SH3 DOMAIN PROTEIN 1 actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;anchoring junction#GO:0070161 GORGO|Ensembl=ENSGGOG00000001937.3|UniProtKB=G3QHS3 G3QHS3 LPAR5 PTHR24234:SF6 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 5 multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to stress#GO:0006950 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000022960.2|UniProtKB=G3SHR9 G3SHR9 CLEC4C PTHR22802:SF423 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER C binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376;defense response to fungus#GO:0050832;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000043554.1|UniProtKB=G3RZD6 G3RZD6 KRBOX1 PTHR23232:SF139 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009056.3|UniProtKB=G3R109 G3R109 SLC39A5 PTHR12191:SF17 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP5 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293 establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;import across plasma membrane#GO:0098739;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;intracellular monoatomic ion homeostasis#GO:0006873 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004598.3|UniProtKB=G3QPL4 G3QPL4 ACSL5 PTHR43272:SF112 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 5 ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 acyl-CoA metabolic process#GO:0006637;nucleoside phosphate biosynthetic process#GO:1901293;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;positive regulation of cellular process#GO:0048522;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;regulation of localization#GO:0032879;nucleobase-containing small molecule metabolic process#GO:0055086;regulation of transport#GO:0051049;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;sulfur compound metabolic process#GO:0006790;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000024635.2|UniProtKB=G3SJS3 G3SJS3 LOC101152643 PTHR11571:SF244 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364 xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000003665.3|UniProtKB=G3QM71 G3QM71 TRAPPC5 PTHR20902:SF0 41-2 PROTEIN ANTIGEN-RELATED TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 TRAPP complex#GO:0030008;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 GORGO|Ensembl=ENSGGOG00000010438.3|UniProtKB=G3R4H8 G3R4H8 LINGO1 PTHR24369:SF178 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000010990.3|UniProtKB=G3R5X9 G3R5X9 PTHR10515:SF0 THYMIDINE PHOSPHORYLASE THYMIDINE PHOSPHORYLASE pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 glycosyltransferase#PC00111 Salvage pyrimidine deoxyribonucleotides#P02774>Uracil phosphorylase#P03145;Pyrimidine Metabolism#P02771>Nucleoside Phosphorylase#P03126;Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine phosphorylase#P03148 GORGO|Ensembl=ENSGGOG00000013746.3|UniProtKB=G3RD20 G3RD20 ALPK2 PTHR47091:SF2 ALPHA-PROTEIN KINASE 2-RELATED ALPHA-PROTEIN KINASE 2 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007630.3|UniProtKB=G3QXC2 G3QXC2 PTHR40143:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000006719.3|UniProtKB=G3QV12 G3QV12 KLHDC8B PTHR46260:SF2 RING-TYPE DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 8B cellular process#GO:0009987;organelle organization#GO:0006996;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;cell division#GO:0051301;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cytoskeleton-dependent cytokinesis#GO:0061640;organelle fission#GO:0048285;mitotic cytokinetic process#GO:1902410;cytokinetic process#GO:0032506;nuclear division#GO:0000280;cytokinesis#GO:0000910 cell periphery#GO:0071944;midbody#GO:0030496;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 GORGO|Ensembl=ENSGGOG00000007800.4|UniProtKB=G3QXS3 G3QXS3 ANXA10 PTHR10502:SF100 ANNEXIN ANNEXIN A10 phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phospholipid binding#GO:0005543 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000014951.3|UniProtKB=G3RVM0 G3RVM0 ZNF567 PTHR24381:SF444 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 567 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000041969.1|UniProtKB=A0A2I2Y9F5 A0A2I2Y9F5 NXPE3 PTHR16165:SF9 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 GORGO|Ensembl=ENSGGOG00000041877.1|UniProtKB=A0A2I2ZU31 A0A2I2ZU31 LOC101129940 PTHR45837:SF3 VESICLE-TRAFFICKING PROTEIN SEC22B VESICLE-TRAFFICKING PROTEIN SEC22B SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043;Golgi organization#GO:0007030;vesicle fusion#GO:0006906;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;membrane organization#GO:0061024 Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;intracellular vesicle#GO:0097708;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;coated vesicle membrane#GO:0030662;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;ER to Golgi transport vesicle membrane#GO:0012507;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;endoplasmic reticulum subcompartment#GO:0098827;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;vesicle#GO:0031982;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000004889.3|UniProtKB=G3S4G8 G3S4G8 ZNF155 PTHR24377:SF430 IP01015P-RELATED ZINC FINGER PROTEIN 155 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000042452.1|UniProtKB=G3SG93 G3SG93 LOC101129167 PTHR23428:SF390 HISTONE H2B HISTONE H2B TYPE 1-O response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;response to external stimulus#GO:0009605;defense response#GO:0006952 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000044182.1|UniProtKB=A0A2I2ZKQ3 A0A2I2ZKQ3 TOR4A PTHR10760:SF1 TORSIN TORSIN-4A endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000027338.2|UniProtKB=G3RSJ3 G3RSJ3 SAGE1 PTHR12957:SF36 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED SAGE1-LIKE PROTEIN-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;integrator complex#GO:0032039;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000023654.2|UniProtKB=A0A2I2YYM9 A0A2I2YYM9 LOC101153713 PTHR24068:SF126 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 S aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000008676.3|UniProtKB=G3R013 G3R013 NAA15 PTHR22767:SF6 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 15, NATA AUXILIARY SUBUNIT enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000024332.2|UniProtKB=G3RX11 G3RX11 UBE2N PTHR24068:SF540 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 N ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;response to stimulus#GO:0050896;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 Toll receptor signaling pathway#P00054>Ubc13#P01381;Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000014389.3|UniProtKB=G3REP2 G3REP2 GLRA1 PTHR18945:SF213 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-1 monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride channel activity#GO:0005254;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476 cell junction#GO:0030054;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;organelle#GO:0043226;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000008930.3|UniProtKB=G3R0P3 G3R0P3 MAOA PTHR43563:SF11 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] A catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 serotonin metabolic process#GO:0042428;metabolic process#GO:0008152;amine catabolic process#GO:0009310;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;phenol-containing compound metabolic process#GO:0018958;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidase#PC00175;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401;Dopamine receptor mediated signaling pathway#P05912>MAO#P05963;Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067 GORGO|Ensembl=ENSGGOG00000008375.3|UniProtKB=A0A2I2ZFH0 A0A2I2ZFH0 TRPM8 PTHR13800:SF9 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 8 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;monoatomic cation transmembrane transporter activity#GO:0008324 calcium ion transport#GO:0006816;system process#GO:0003008;establishment of localization#GO:0051234;transport#GO:0006810;regulation of multicellular organismal process#GO:0051239;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;nervous system process#GO:0050877;sensory perception#GO:0007600;metal ion transport#GO:0030001;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000003801.3|UniProtKB=A0A2I2Y851 A0A2I2Y851 PLCD1 PTHR10336:SF210 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-1 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;lipase activity#GO:0016298 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484 GORGO|Ensembl=ENSGGOG00000002315.3|UniProtKB=A0A2I2Z713 A0A2I2Z713 CCDC83 PTHR21468:SF1 HSD9 COILED-COIL DOMAIN-CONTAINING PROTEIN 83 GORGO|Ensembl=ENSGGOG00000013205.3|UniProtKB=G3RM14 G3RM14 ALAS1 PTHR13693:SF50 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, NON-SPECIFIC, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000041097.1|UniProtKB=A0A2I2Y8J4 A0A2I2Y8J4 PTHR23232:SF178 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN 5-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005424.3|UniProtKB=G3QRQ7 G3QRQ7 INTS8 PTHR13350:SF1 INTEGRATOR COMPLEX SUBUNIT 8 INTEGRATOR COMPLEX SUBUNIT 8 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;snRNA processing#GO:0016180;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;integrator complex#GO:0032039;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000006803.3|UniProtKB=G3QV98 G3QV98 PSMC5 PTHR23073:SF12 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 8 isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 proteasome complex#GO:0000502;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000014031.3|UniProtKB=G3RDS3 G3RDS3 PTHR13531:SF8 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 80 cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515 ciliary transition zone#GO:0035869;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000022016.2|UniProtKB=G3SEM7 G3SEM7 PON2 PTHR11799:SF17 PARAOXONASE SERUM PARAOXONASE_ARYLESTERASE 2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to toxic substance#GO:0009636 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000011049.3|UniProtKB=G3R653 G3R653 COL4A5 PTHR24023:SF1029 COLLAGEN ALPHA COLLAGEN ALPHA-5(IV) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000006721.3|UniProtKB=G3QV16 G3QV16 PTHR13857:SF39 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3B hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular process#GO:0009987;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;RNA modification#GO:0009451;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;base conversion or substitution editing#GO:0016553;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to other organism#GO:0051707;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cytidine to uridine editing#GO:0016554;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;response to virus#GO:0009615;macromolecule modification#GO:0043412 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000013217.3|UniProtKB=G3RBN1 G3RBN1 SARNP PTHR46551:SF2 SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000373.3|UniProtKB=G3QDP2 G3QDP2 SLC13A4 PTHR10283:SF63 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000000499.3|UniProtKB=G3S7V6 G3S7V6 IRF3 PTHR11949:SF1 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 Toll receptor signaling pathway#P00054>IRF3#P01374 GORGO|Ensembl=ENSGGOG00000014076.3|UniProtKB=G3RDX5 G3RDX5 AATK PTHR24417:SF0 SERINE/THREONINE-PROTEIN KINASE LMTK1 SERINE_THREONINE-PROTEIN KINASE LMTK1 protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular process#GO:0009987;multicellular organismal process#GO:0032501;brain development#GO:0007420;head development#GO:0060322;nervous system development#GO:0007399;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;programmed cell death#GO:0012501;cell death#GO:0008219;apoptotic process#GO:0006915;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;neuron apoptotic process#GO:0051402;system development#GO:0048731 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000003795.3|UniProtKB=A0A2I2Y4I2 A0A2I2Y4I2 DCN PTHR45712:SF14 AGAP008170-PA DECORIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000039315.1|UniProtKB=A0A2I2Z3C9 A0A2I2Z3C9 RGS22 PTHR46583:SF1 REGULATOR OF G-PROTEIN SIGNALING 22 REGULATOR OF G PROTEIN SIGNALING 22 binding#GO:0005488;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007734.3|UniProtKB=G3QXL8 G3QXL8 CPXM1 PTHR11532:SF43 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE X1-RELATED carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;proteolysis#GO:0006508;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 GORGO|Ensembl=ENSGGOG00000013409.3|UniProtKB=G3RC57 G3RC57 FAM76B PTHR46176:SF3 LD21662P PROTEIN FAM76B intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000022064.2|UniProtKB=G3RQ88 G3RQ88 PTHR24054:SF34 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA' protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;regulation of cellular process#GO:0050794;regulation of chromosome separation#GO:1905818;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stress#GO:0006950;cellular response to stress#GO:0033554;regulation of chromosome segregation#GO:0051983;DNA damage response#GO:0006974 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459 GORGO|Ensembl=ENSGGOG00000001790.3|UniProtKB=G3S360 G3S360 BAG5 PTHR12329:SF2 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 5 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589 negative regulation of protein ubiquitination#GO:0031397;regulation of biological quality#GO:0065008;regulation of post-translational protein modification#GO:1901873;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;protein stabilization#GO:0050821;regulation of protein modification process#GO:0031399;regulation of protein stability#GO:0031647;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane#GO:0016020 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000004678.3|UniProtKB=G3QPT3 G3QPT3 ANXA1 PTHR10502:SF17 ANNEXIN ANNEXIN A1 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;binding#GO:0005488;anion binding#GO:0043168;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;ion binding#GO:0043167 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to steroid hormone#GO:0048545;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;localization#GO:0051179;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;biological regulation#GO:0065007;phagocytosis#GO:0006909;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular response to steroid hormone stimulus#GO:0071383 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000006737.3|UniProtKB=G3QV40 G3QV40 DLG4 PTHR23119:SF33 DISCS LARGE DISKS LARGE HOMOLOG 4 structural molecule activity#GO:0005198;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;structural constituent of synapse#GO:0098918;protein binding#GO:0005515 nervous system development#GO:0007399;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;cellular process#GO:0009987;multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;cellular component organization or biogenesis#GO:0071840;signaling#GO:0023052;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;cell adhesion#GO:0007155;receptor clustering#GO:0043113;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;developmental process#GO:0032502;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;postsynapse organization#GO:0099173;chemical synaptic transmission#GO:0007268;anatomical structure development#GO:0048856;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;cell communication#GO:0007154;system development#GO:0048731;establishment or maintenance of apical/basal cell polarity#GO:0035088;trans-synaptic signaling#GO:0099537;protein localization to cell junction#GO:1902414;establishment or maintenance of bipolar cell polarity#GO:0061245;localization within membrane#GO:0051668;synapse organization#GO:0050808 neuromuscular junction#GO:0031594;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 Huntington disease#P00029>PSD-95#P00789 GORGO|Ensembl=ENSGGOG00000006074.3|UniProtKB=G3SI01 G3SI01 HDDC2 PTHR11845:SF13 5'-DEOXYNUCLEOTIDASE HDDC2 5'-DEOXYNUCLEOTIDASE HDDC2 phosphatase activity#GO:0016791;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000015406.2|UniProtKB=G3RHB1 G3RHB1 DIO1 PTHR11781:SF22 IODOTHYRONINE DEIODINASE TYPE I IODOTHYRONINE DEIODINASE metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000016322.3|UniProtKB=A0A2I2YJW8 A0A2I2YJW8 CHML PTHR11787:SF9 RAB GDP-DISSOCIATION INHIBITOR RAB PROTEINS GERANYLGERANYLTRANSFERASE COMPONENT A 2 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;transport#GO:0006810;protein targeting to membrane#GO:0006612;vesicle-mediated transport#GO:0016192;protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000016043.3|UniProtKB=G3RIY8 G3RIY8 LOC101145461 PTHR10662:SF46 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015094.3|UniProtKB=G3RGJ8 G3RGJ8 DOCK1 PTHR45653:SF1 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 1 enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 developmental process#GO:0032502;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;striated muscle cell differentiation#GO:0051146;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;myoblast fusion#GO:0007520;cell differentiation#GO:0030154;muscle structure development#GO:0061061;cell migration#GO:0016477;cell motility#GO:0048870 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 Integrin signalling pathway#P00034>Dock180#P00930 GORGO|Ensembl=ENSGGOG00000038992.1|UniProtKB=A0A2I2ZHV5 A0A2I2ZHV5 SLC40A1 PTHR11660:SF47 SOLUTE CARRIER FAMILY 40 MEMBER FERROPORTIN monoatomic cation transmembrane transporter activity#GO:0008324;iron ion transmembrane transporter activity#GO:0005381;transition metal ion transmembrane transporter activity#GO:0046915;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;peptide hormone binding#GO:0017046;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;hormone binding#GO:0042562 cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;iron ion transport#GO:0006826;iron ion transmembrane transport#GO:0034755;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014360.3|UniProtKB=G3REL8 G3REL8 ACBD4 PTHR23310:SF53 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4 heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000043923.1|UniProtKB=A0A2I2ZEP0 A0A2I2ZEP0 STMND1 PTHR10104:SF20 STATHMIN STATHMIN DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 protein-containing complex disassembly#GO:0032984;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;system development#GO:0048731;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;protein depolymerization#GO:0051261;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular component disassembly#GO:0022411;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;microtubule depolymerization#GO:0007019;neuron differentiation#GO:0030182;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000005758.3|UniProtKB=G3QSJ7 G3QSJ7 FRZB PTHR11309:SF97 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 3 molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 non-canonical Wnt signaling pathway#GO:0035567;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>FrzB#P01461;Angiogenesis#P00005>FRP#P00237 GORGO|Ensembl=ENSGGOG00000042175.1|UniProtKB=A0A2I2YB83 A0A2I2YB83 PTHR10351:SF28 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000000347.3|UniProtKB=G3QDL9 G3QDL9 PPME1 PTHR14189:SF0 PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED PROTEIN PHOSPHATASE METHYLESTERASE 1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011779.3|UniProtKB=G3RXZ3 G3RXZ3 ROBO2 PTHR13817:SF69 TITIN ROUNDABOUT GUIDANCE RECEPTOR 2 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000001170.3|UniProtKB=G3RNP7 G3RNP7 KIAA0930 PTHR21477:SF13 ZGC:172139 KIAA0930 GORGO|Ensembl=ENSGGOG00000014908.3|UniProtKB=A0A2I2ZUG7 A0A2I2ZUG7 PAX2 PTHR45636:SF19 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000004046.3|UniProtKB=G3QN64 G3QN64 TRABD2A PTHR31120:SF7 METALLOPROTEASE TIKI METALLOPROTEASE TIKI1 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000042586.1|UniProtKB=A0A2I2ZW14 A0A2I2ZW14 ZNF445 PTHR23226:SF259 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 445 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016481.3|UniProtKB=A0A2I2Y921 A0A2I2Y921 DNMBP PTHR22834:SF19 NUCLEAR FUSION PROTEIN FUS2 DYNAMIN-BINDING PROTEIN molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000010692.3|UniProtKB=G3R560 G3R560 LEF1 PTHR10373:SF11 TRANSCRIPTION FACTOR 7 FAMILY MEMBER LYMPHOID ENHANCER-BINDING FACTOR 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Cadherin signaling pathway#P00012>TCF/LEF#P00465;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Wnt signaling pathway#P00057>TCF#P01437 GORGO|Ensembl=ENSGGOG00000043461.1|UniProtKB=A0A2I2YGW7 A0A2I2YGW7 BRD2 PTHR22880:SF240 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 2 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000011134.3|UniProtKB=G3SC41 G3SC41 FCHO1 PTHR23065:SF6 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 F-BAR DOMAIN ONLY PROTEIN 1 transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;cellular component assembly#GO:0022607;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 clathrin-coated vesicle#GO:0030136;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000042613.1|UniProtKB=A0A2I2YHS9 A0A2I2YHS9 UBE2H PTHR24068:SF128 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 H aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000005307.3|UniProtKB=G3QRE5 G3QRE5 LOC101151012 PTHR26450:SF98 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52A1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000017127.3|UniProtKB=G3RFV2 G3RFV2 LOC101138909 PTHR45615:SF69 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-6 isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Wnt signaling pathway#P00057>NFAT Target Genes#G01559 GORGO|Ensembl=ENSGGOG00000001747.3|UniProtKB=G3QH96 G3QH96 PUS7L PTHR13326:SF21 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE PUS7L isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 RNA modification#GO:0009451;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;pseudouridine synthesis#GO:0001522;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000001185.3|UniProtKB=G3QFT9 G3QFT9 RIDA PTHR11803:SF53 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA 2-IMINOBUTANOATE_2-IMINOPROPANOATE DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239;catalytic activity#GO:0003824 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of protein metabolic process#GO:0051248;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of protein metabolic process#GO:0051246;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000024061.2|UniProtKB=A0A2I2Y708 A0A2I2Y708 LOC101145384 PTHR13164:SF3 CALICYLIN BINDING PROTEIN CALCYCLIN-BINDING PROTEIN ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 multicellular organismal process#GO:0032501;heart development#GO:0007507;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000027736.2|UniProtKB=G3RSY4 G3RSY4 LOC101153683 PTHR26453:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008285.3|UniProtKB=G3QZ07 G3QZ07 TTF1 PTHR46760:SF1 TRANSCRIPTION TERMINATION FACTOR 1 TRANSCRIPTION TERMINATION FACTOR 1 General transcription regulation#P00023>TTF2#P00661;General transcription by RNA polymerase I#P00022>TTF-I#P00654;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 GORGO|Ensembl=ENSGGOG00000000849.3|UniProtKB=G3QEX9 G3QEX9 GPR12 PTHR22750:SF8 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 12 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000003816.3|UniProtKB=G3QMK6 G3QMK6 LY6K PTHR15049:SF1 GLYCOSYL-PHOSPHATIDYLINOSITOL-ANCHORED MOLECULE-LIKE PROTEIN-RELATED LYMPHOCYTE ANTIGEN 6K cell recognition#GO:0008037;sexual reproduction#GO:0019953;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988;binding of sperm to zona pellucida#GO:0007339;cellular process#GO:0009987;single fertilization#GO:0007338;fertilization#GO:0009566;reproductive process#GO:0022414 intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000004311.3|UniProtKB=G3QNU9 G3QNU9 HAND1 PTHR23349:SF3 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;heart development#GO:0007507;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;circulatory system development#GO:0072359;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000002553.3|UniProtKB=G3QJC9 G3QJC9 PLXNC1 PTHR22625:SF4 PLEXIN PLEXIN-C1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;cellular component assembly#GO:0022607;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell differentiation#GO:0045597;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of axonogenesis#GO:0050770 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027386.2|UniProtKB=G3SCI5 G3SCI5 KCNK18 PTHR11003:SF346 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 18 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000000442.3|UniProtKB=G3QDV7 G3QDV7 TTBK1 PTHR11909:SF297 CASEIN KINASE-RELATED TAU-TUBULIN KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000026439.2|UniProtKB=G3S6X5 G3S6X5 SUMO1 PTHR10562:SF148 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 1 ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231 p53 pathway#P00059>Sumo-1 ligase#P04635 GORGO|Ensembl=ENSGGOG00000025531.2|UniProtKB=G3RY93 G3RY93 PTHR23232:SF124 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 708 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000040163.1|UniProtKB=A0A2I2Z583 A0A2I2Z583 HAS2 PTHR22913:SF7 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 2 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;cellular component biogenesis#GO:0044085;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan biosynthetic process#GO:0006023;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;polysaccharide biosynthetic process#GO:0000271;extracellular structure organization#GO:0043062;aminoglycan metabolic process#GO:0006022;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000044087.1|UniProtKB=A0A2I2Z5F4 A0A2I2Z5F4 LOC101128800 PTHR15469:SF2 NADH-UBIQUINONE OXIDOREDUCTASE B15 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000044036.1|UniProtKB=A0A2I2YE57 A0A2I2YE57 LBHD2 PTHR14987:SF3 PROTEIN LBH-RELATED LBH DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000015783.3|UniProtKB=A0A2I2YQ44 A0A2I2YQ44 PPIE PTHR11071:SF593 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000002489.3|UniProtKB=A0A2I2YK84 A0A2I2YK84 THAP6 PTHR47577:SF1 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN-CONTAINING PROTEIN 6 GORGO|Ensembl=ENSGGOG00000026056.2|UniProtKB=A0A2I2ZVV8 A0A2I2ZVV8 PTHR11559:SF441 CARBOXYLESTERASE LIVER CARBOXYLESTERASE 1-RELATED hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 short-chain fatty acid catabolic process#GO:0019626;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000006188.3|UniProtKB=G3QTM5 G3QTM5 CA13 PTHR18952:SF81 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 13-RELATED hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000022958.2|UniProtKB=G3S0X7 G3S0X7 PTHR46254:SF3 PROTEIN GVQW1-RELATED 4FE-4S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000023923.2|UniProtKB=G3SEY9 G3SEY9 PTHR23267:SF108 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 6-57 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000001027.3|UniProtKB=G3S1G8 G3S1G8 DOCK3 PTHR45653:SF4 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 3 binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000006425.3|UniProtKB=G3QUA2 G3QUA2 FBN2 PTHR24040:SF7 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN FIBRILLIN 2B cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000016930.3|UniProtKB=G3RL82 G3RL82 EEF1AKMT1 PTHR13200:SF0 EEF1A LYSINE METHYLTRANSFERASE 1 EEF1A LYSINE METHYLTRANSFERASE 1 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 GORGO|Ensembl=ENSGGOG00000008888.3|UniProtKB=G3R0K0 G3R0K0 CARHSP1 PTHR12962:SF3 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED CALCIUM-REGULATED HEAT-STABLE PROTEIN 1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010749.3|UniProtKB=G3RQ47 G3RQ47 MOSPD3 PTHR34441:SF4 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000012054.3|UniProtKB=G3R8P1 G3R8P1 IQCF6 PTHR21633:SF15 IQ MOTIF CONTAINING F IQ DOMAIN-CONTAINING PROTEIN F6 GORGO|Ensembl=ENSGGOG00000002771.3|UniProtKB=G3QJX5 G3QJX5 USP15 PTHR21646:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;nucleic acid biosynthetic process#GO:0141187;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;biological regulation#GO:0065007;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of protein stability#GO:0031647;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000022616.2|UniProtKB=G3SJQ2 G3SJQ2 MSS51 PTHR46920:SF1 FAMILY NOT NAMED PROTEIN MSS51 HOMOLOG, MITOCHONDRIAL-RELATED GORGO|Ensembl=ENSGGOG00000007568.3|UniProtKB=A0A2I2Y7F2 A0A2I2Y7F2 ECE2 PTHR11733:SF127 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED EEF1AKMT4-ECE2 READTHROUGH TRANSCRIPT PROTEIN-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 GORGO|Ensembl=ENSGGOG00000022887.2|UniProtKB=G3S4S9 G3S4S9 FAM131C PTHR15736:SF2 PROTEIN FAM131B-RELATED PROTEIN FAM131C GORGO|Ensembl=ENSGGOG00000041041.1|UniProtKB=A0A2I2Z279 A0A2I2Z279 GPRIN3 PTHR15718:SF6 G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH C-TERMINAL DOMAIN-CONTAINING PROTEIN G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 3 cellular component organization#GO:0016043;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000043975.1|UniProtKB=P47782 P47782 RNASE2 PTHR11437:SF62 RIBONUCLEASE NON-SECRETORY RIBONUCLEASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;taxis#GO:0042330;response to chemical#GO:0042221;response to other organism#GO:0051707;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;chemotaxis#GO:0006935;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;locomotion#GO:0040011;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000041359.1|UniProtKB=G3R3H6 G3R3H6 C1QB PTHR15427:SF18 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT B signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of immune response#GO:0050776;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;immune response#GO:0006955;complement activation#GO:0006956;positive regulation of immune system process#GO:0002684;adaptive immune response#GO:0002250;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778;humoral immune response#GO:0006959 protein-containing complex#GO:0032991;glutamatergic synapse#GO:0098978;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;synaptic membrane#GO:0097060;extracellular protein-containing complex#GO:0140392;cellular anatomical structure#GO:0110165;synapse#GO:0045202;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013783.3|UniProtKB=G3RD54 G3RD54 PKNOX1 PTHR11850:SF80 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN PKNOX1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;tube development#GO:0035295;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;angiogenesis#GO:0001525;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Prep1#P06829 GORGO|Ensembl=ENSGGOG00000038570.1|UniProtKB=G3S0I1 G3S0I1 PTHR23266:SF379 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-3 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010511.3|UniProtKB=G3R4P7 G3R4P7 MRPL37 PTHR15889:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L37 LARGE RIBOSOMAL SUBUNIT PROTEIN ML37 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011614.3|UniProtKB=G3R7J5 G3R7J5 ZP4 PTHR23343:SF31 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 4 protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;enzyme binding#GO:0019899;extracellular matrix structural constituent#GO:0005201 sperm-egg recognition#GO:0035036;sexual reproduction#GO:0019953;cell activation#GO:0001775;cell recognition#GO:0008037;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988;negative regulation of biological process#GO:0048519;single fertilization#GO:0007338;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;reproductive process#GO:0022414;fertilization#GO:0009566 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040641.1|UniProtKB=G3RFD0 G3RFD0 ZNF563 PTHR24379:SF14 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 563 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000000080.3|UniProtKB=G3QCX7 G3QCX7 DTD1 PTHR10472:SF5 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 1 carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;deacylase activity#GO:0160215;catalytic activity, acting on RNA#GO:0140098 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 GORGO|Ensembl=ENSGGOG00000043560.1|UniProtKB=G3QPG8 G3QPG8 LOC101141027 PTHR24379:SF131 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 712 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006651.4|UniProtKB=G3QUV5 G3QUV5 RASEF PTHR47977:SF73 RAS-RELATED PROTEIN RAB RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;GDP binding#GO:0019003;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165 small GTPase#PC00208 GORGO|Gene=C2|UniProtKB=Q863A0 Q863A0 C2 PTHR46393:SF2 SUSHI DOMAIN-CONTAINING PROTEIN COMPLEMENT C2 response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;immune system process#GO:0002376;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;complement activation#GO:0006956;activation of immune response#GO:0002253;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;response to external stimulus#GO:0009605;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;humoral immune response#GO:0006959 GORGO|Ensembl=ENSGGOG00000042585.1|UniProtKB=A0A2I2ZLR0 A0A2I2ZLR0 PTHR23316:SF66 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006572.3|UniProtKB=G3QUM5 G3QUM5 FAM111B PTHR14389:SF4 SI:CH1073-475A24.1 SERINE PROTEASE FAM111B serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 response to stress#GO:0006950;cellular process#GO:0009987;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000040194.1|UniProtKB=A0A2I2ZQX9 A0A2I2ZQX9 PTHR12700:SF16 ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT D, MITOCHONDRIAL channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874 small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;organophosphate biosynthetic process#GO:0090407;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293 organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;organelle membrane#GO:0031090;transporter complex#GO:1990351;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016862.3|UniProtKB=G3RL13 G3RL13 CXCR4 PTHR10489:SF594 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 4 cytokine receptor activity#GO:0004896;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cellular developmental process#GO:0048869;calcium-mediated signaling#GO:0019722;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell migration#GO:0016477;brain development#GO:0007420;biological regulation#GO:0065007;immune response#GO:0006955;anatomical structure development#GO:0048856;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;system development#GO:0048731;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;cell motility#GO:0048870;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;animal organ development#GO:0048513;multicellular organism development#GO:0007275;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;head development#GO:0060322;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;response to stimulus#GO:0050896;central nervous system development#GO:0007417;cell differentiation#GO:0030154;signaling#GO:0023052;regulation of biological process#GO:0050789 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854;Axon guidance mediated by Slit/Robo#P00008>Cxcr4#P00351 GORGO|Ensembl=ENSGGOG00000011600.3|UniProtKB=G3R7I6 G3R7I6 PTHR22780:SF13 ADAPTIN, ALPHA/GAMMA/EPSILON AP-4 COMPLEX SUBUNIT EPSILON-1 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;membrane coat#GO:0030117;coated membrane#GO:0048475 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000004225.3|UniProtKB=G3QNM9 G3QNM9 BRIX1 PTHR13634:SF0 RIBOSOME BIOGENESIS PROTEIN BRIX RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cellular process#GO:0009987;ribosomal large subunit assembly#GO:0000027;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009133.3|UniProtKB=G3S5L2 G3S5L2 SALL2 PTHR23233:SF15 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011754.3|UniProtKB=G3R7X4 G3R7X4 EHBP1L1 PTHR23167:SF42 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED EH DOMAIN-BINDING PROTEIN 1-LIKE PROTEIN 1 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040236.1|UniProtKB=A0A2I2Z9M4 A0A2I2Z9M4 PTHR12552:SF3 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 42 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000011327.3|UniProtKB=G3R6S7 G3R6S7 TLDC2 PTHR23354:SF65 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED TLD DOMAIN-CONTAINING PROTEIN 2 response to stimulus#GO:0050896;response to oxidative stress#GO:0006979;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000027625.2|UniProtKB=G3SES0 G3SES0 CLIP4 PTHR18916:SF32 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 4 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;nucleus#GO:0005634;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule end#GO:1990752;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000009939.3|UniProtKB=G3R386 G3R386 STRAP PTHR19877:SF19 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;SMN complex#GO:0032797;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737 translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000003362.3|UniProtKB=G3QLG1 G3QLG1 CNTNAP1 PTHR15036:SF43 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN 1 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;myelination#GO:0042552;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000038095.1|UniProtKB=G3SFM6 G3SFM6 MZB1 PTHR15881:SF2 MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of immune effector process#GO:0002697;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;positive regulation of immune system process#GO:0002684;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000009816.3|UniProtKB=A0A2I2YG10 A0A2I2YG10 BCAT1 PTHR11825:SF70 SUBGROUP IIII AMINOTRANSFERASE BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE, CYTOSOLIC catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transferase#PC00220;transaminase#PC00216 Isoleucine biosynthesis#P02748>Branched chain amino acid aminotransferase#P02994;Valine biosynthesis#P02785>Branched chain amino acid aminotransferase#P03215;Alanine biosynthesis#P02724>Branched chain amino acid aminotransferase#P02815;Leucine biosynthesis#P02749>Branched chain amino acid aminotransferase#P03000 GORGO|Ensembl=ENSGGOG00000007182.3|UniProtKB=G3QW80 G3QW80 GPD1L PTHR11728:SF7 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE 1-LIKE PROTEIN oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000006010.3|UniProtKB=G3QT70 G3QT70 LPAR2 PTHR22750:SF38 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000014574.3|UniProtKB=G3RF65 G3RF65 PPP1R12A PTHR24179:SF20 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12A phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;enzyme inhibitor activity#GO:0004857 cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856 sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;A band#GO:0031672 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000011666.3|UniProtKB=G3R7N3 G3R7N3 UPRT PTHR10285:SF171 URIDINE KINASE URACIL PHOSPHORIBOSYLTRANSFERASE HOMOLOG cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uracil phosphoribosyl transferase#P03151 GORGO|Ensembl=ENSGGOG00000003742.3|UniProtKB=G3QME0 G3QME0 RIC3 PTHR21723:SF3 RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3 PROTEIN RIC-3 trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular process#GO:0009987;anterograde trans-synaptic signaling#GO:0098916;synaptic transmission, cholinergic#GO:0007271;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;cell projection#GO:0042995;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009336.3|UniProtKB=G3RP42 G3RP42 ARL13A PTHR46090:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13A cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;localization within membrane#GO:0051668;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;non-motile cilium assembly#GO:1905515 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cell projection membrane#GO:0031253;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;plasma membrane region#GO:0098590 GORGO|Ensembl=ENSGGOG00000001906.3|UniProtKB=G3QHP7 G3QHP7 KRIT1 PTHR13283:SF11 KREV INTERACTION TRAPPED 1-RELATED KREV INTERACTION TRAPPED PROTEIN 1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 multicellular organism development#GO:0007275;negative regulation of angiogenesis#GO:0016525;anterior/posterior axis specification#GO:0009948;regulation of anatomical structure morphogenesis#GO:0022603;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;anterior/posterior pattern specification#GO:0009952;regulation of vasculature development#GO:1901342;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of establishment or maintenance of cell polarity#GO:0032878;regionalization#GO:0003002;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;anatomical structure development#GO:0048856;regulation of angiogenesis#GO:0045765;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;regulation of developmental process#GO:0050793;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022316.2|UniProtKB=G3RZD4 G3RZD4 TSPAN19 PTHR19282:SF211 TETRASPANIN TETRASPANIN-19 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012808.3|UniProtKB=G3RAL5 G3RAL5 MRPS10 PTHR13334:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN US10M intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005211.3|UniProtKB=G3QR65 G3QR65 PIK3IP1 PTHR24261:SF16 PLASMINOGEN-RELATED PHOSPHOINOSITIDE-3-KINASE-INTERACTING PROTEIN 1 binding#GO:0005488;signaling receptor binding#GO:0005102;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015730.3|UniProtKB=G3RI58 G3RI58 MSMO1 PTHR11863:SF225 STEROL DESATURASE METHYLSTEROL MONOOXYGENASE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;secondary alcohol biosynthetic process#GO:1902653;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000011191.3|UniProtKB=G3R6F8 G3R6F8 PTHR24306:SF0 FAMILY NOT NAMED 7-ALPHA-HYDROXYCHOLEST-4-EN-3-ONE 12-ALPHA-HYDROXYLASE catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 GORGO|Ensembl=ENSGGOG00000003344.3|UniProtKB=A0A2I2ZQ88 A0A2I2ZQ88 IL1R1 PTHR11890:SF26 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR TYPE 1 cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of response to external stimulus#GO:0032101;signaling#GO:0023052;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;cell surface receptor signaling pathway#GO:0007166;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;cell communication#GO:0007154 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 p38 MAPK pathway#P05918>IL-1R#P06030 GORGO|Ensembl=ENSGGOG00000007969.3|UniProtKB=A0A2I2ZI20 A0A2I2ZI20 SPAG4 PTHR12911:SF16 SAD1/UNC-84-LIKE PROTEIN-RELATED SPERM-ASSOCIATED ANTIGEN 4 PROTEIN protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane#GO:0016020 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000003619.3|UniProtKB=G3RF61 G3RF61 BTN2A1 PTHR24100:SF79 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 2 MEMBER A1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000013597.3|UniProtKB=G3RCM8 G3RCM8 LOC101132889 PTHR10353:SF291 GLYCOSYL HYDROLASE CYTOSOLIC BETA-GLUCOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;carbohydrate derivative catabolic process#GO:1901136 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000028420.2|UniProtKB=G3SEJ0 G3SEJ0 DDX18 PTHR24031:SF634 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX18 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005335.3|UniProtKB=A0A2I2ZVU2 A0A2I2ZVU2 IL6 PTHR48494:SF1 INTERLEUKIN-6 INTERLEUKIN-6 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;cell communication#GO:0007154;response to peptide#GO:1901652;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;defense response#GO:0006952 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Interleukin signaling pathway#P00036>Interleukin#P00970;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 GORGO|Gene=RNASE9|UniProtKB=Q863K0 Q863K0 RNASE9 PTHR11437:SF14 RIBONUCLEASE INACTIVE RIBONUCLEASE-LIKE PROTEIN 9 RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009660.3|UniProtKB=A0A2I2ZGC2 A0A2I2ZGC2 PTHR10720:SF1 HEME OXYGENASE HEME OXYGENASE 1 heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;response to oxidative stress#GO:0006979;pigment metabolic process#GO:0042440;response to stress#GO:0006950;cellular process#GO:0009987;response to stimulus#GO:0050896;catabolic process#GO:0009056;heme metabolic process#GO:0042168 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000036439.1|UniProtKB=G3S8R0 G3S8R0 MYH8 PTHR45615:SF35 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-8 macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 muscle system process#GO:0003012;muscle contraction#GO:0006936;multicellular organismal process#GO:0032501;system process#GO:0003008 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 GORGO|Ensembl=ENSGGOG00000008204.3|UniProtKB=G3RSS2 G3RSS2 B4GALNT2 PTHR15046:SF2 GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN N-ACETYLNEURAMINYLGALACTOSYLGLUCOSYL-GLUCOSIDE BETA-1,4-N- ACETYLGALACTOSAMINYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376 nucleobase-containing small molecule metabolic process#GO:0055086;UDP-N-acetylglucosamine metabolic process#GO:0006047;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637 GORGO|Ensembl=ENSGGOG00000013559.3|UniProtKB=G3RCJ0 G3RCJ0 DHRS9 PTHR43313:SF15 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 9 catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;oxoacid metabolic process#GO:0043436;isoprenoid biosynthetic process#GO:0008299;terpenoid metabolic process#GO:0006721;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;regulation of hormone levels#GO:0010817;monocarboxylic acid biosynthetic process#GO:0072330;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;diterpenoid biosynthetic process#GO:0016102;lipid biosynthetic process#GO:0008610;terpenoid biosynthetic process#GO:0016114;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cellular process#GO:0009987 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000009695.3|UniProtKB=G3R2L4 G3R2L4 LOC101154074 PTHR23239:SF207 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 24 structural molecule activity#GO:0005198 intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502 organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000016787.3|UniProtKB=G3RUC7 G3RUC7 MAP4K1 PTHR48012:SF15 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCK#P00268;Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861 GORGO|Ensembl=ENSGGOG00000027904.2|UniProtKB=A0A2I2ZKL9 A0A2I2ZKL9 LOC101145725 PTHR14224:SF81 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 1-RELATED ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 GORGO|Ensembl=ENSGGOG00000026765.2|UniProtKB=G3SBU4 G3SBU4 SPACA5 PTHR11407:SF31 LYSOZYME C SPERM ACROSOME-ASSOCIATED PROTEIN 5 lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783 multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;reproductive process#GO:0022414;single fertilization#GO:0007338;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;cellular process#GO:0009987 secretory vesicle#GO:0099503;endomembrane system#GO:0012505;sperm flagellum#GO:0036126;cytoplasm#GO:0005737;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000002452.3|UniProtKB=G3QJ29 G3QJ29 PCP2 PTHR47503:SF1 PURKINJE CELL PROTEIN 2 PURKINJE CELL PROTEIN 2 HOMOLOG enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 GORGO|Ensembl=ENSGGOG00000010098.3|UniProtKB=A0A2I2YSL5 A0A2I2YSL5 HAUS1 PTHR31570:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;chromosome segregation#GO:0007059;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226 HAUS complex#GO:0070652;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000008461.3|UniProtKB=G3QZG4 G3QZG4 LHCGR PTHR24372:SF1 GLYCOPROTEIN HORMONE RECEPTOR LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organism development#GO:0007275;animal organ development#GO:0048513;development of primary sexual characteristics#GO:0045137;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to chemical#GO:0042221;signal transduction#GO:0007165;male gonad development#GO:0008584;sex differentiation#GO:0007548;cellular process#GO:0009987;response to hormone#GO:0009725;hormone-mediated signaling pathway#GO:0009755;rhythmic process#GO:0048511;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;reproductive structure development#GO:0048608;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;male sex differentiation#GO:0046661;development of primary male sexual characteristics#GO:0046546;biological regulation#GO:0065007;gonad development#GO:0008406;multicellular organismal process#GO:0032501;system development#GO:0048731;female gonad development#GO:0008585;multicellular organismal reproductive process#GO:0048609;reproductive system development#GO:0061458;cell communication#GO:0007154;anatomical structure development#GO:0048856;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;developmental process involved in reproduction#GO:0003006 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000014842.3|UniProtKB=G3RFV3 G3RFV3 CSPG5 PTHR15381:SF1 CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED CHONDROITIN SULFATE PROTEOGLYCAN 5 cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;system development#GO:0048731;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;response to wounding#GO:0009611;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular response to stress#GO:0033554;nervous system development#GO:0007399;regeneration#GO:0031099;response to stress#GO:0006950;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;gliogenesis#GO:0042063;neuron differentiation#GO:0030182 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211 GORGO|Ensembl=ENSGGOG00000004953.3|UniProtKB=G3QQI6 G3QQI6 RNF181 PTHR15710:SF243 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF181 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000007677.3|UniProtKB=G3RQF0 G3RQF0 NOL7 PTHR32337:SF2 NUCLEOLAR PROTEIN 7 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN NOL7 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 GORGO|Ensembl=ENSGGOG00000017135.3|UniProtKB=G3RLQ8 G3RLQ8 SYT9 PTHR10024:SF180 SYNAPTOTAGMIN SYNAPTOTAGMIN-9 protein binding#GO:0005515;molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 synaptic signaling#GO:0099536;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;positive regulation of vesicle fusion#GO:0031340;regulation of localization#GO:0032879;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;positive regulation of cellular component organization#GO:0051130;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion#GO:0051046;positive regulation of organelle organization#GO:0010638;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530 membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000009830.3|UniProtKB=G3R2Y9 G3R2Y9 SLC39A7 PTHR16950:SF25 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER SLC39A7 monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385 monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000005242.3|UniProtKB=G3QR96 G3QR96 ZMIZ1 PTHR10782:SF7 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 1 aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678;SUMO transferase activity#GO:0019789;transcription regulator activity#GO:0140110;SUMO ligase activity#GO:0061665;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;metabolic process#GO:0008152;protein sumoylation#GO:0016925;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000007770.3|UniProtKB=G3QXP5 G3QXP5 SERPINB1 PTHR11461:SF180 SERINE PROTEASE INHIBITOR, SERPIN LEUKOCYTE ELASTASE INHIBITOR endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000038491.1|UniProtKB=A0A2I2YYD5 A0A2I2YYD5 ADAM2 PTHR11905:SF108 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 2 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;fertilization#GO:0009566;reproductive process#GO:0022414;reproductive structure development#GO:0048608;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;sexual reproduction#GO:0019953;cell adhesion#GO:0007155;cell recognition#GO:0008037;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;binding of sperm to zona pellucida#GO:0007339;system development#GO:0048731;reproductive system development#GO:0061458;single fertilization#GO:0007338;male gonad development#GO:0008584;sex differentiation#GO:0007548;cellular process#GO:0009987;multicellular organismal process#GO:0032501;gonad development#GO:0008406;metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;sperm-egg recognition#GO:0035036;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;male sex differentiation#GO:0046661;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;animal organ development#GO:0048513;cell-cell recognition#GO:0009988 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000006142.3|UniProtKB=A0A2I2Z631 A0A2I2Z631 APOF PTHR15011:SF3 APOLIPOPROTEIN F APOLIPOPROTEIN F alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;sterol metabolic process#GO:0016125;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;steroid metabolic process#GO:0008202;secondary alcohol metabolic process#GO:1902652 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000044012.1|UniProtKB=A0A2I2Y204 A0A2I2Y204 LYRM1 PTHR14273:SF0 LYR MOTIF-CONTAINING PROTEIN 1 LYR MOTIF-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000011416.3|UniProtKB=G3R712 G3R712 UBE4A PTHR13931:SF16 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 A acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to endoplasmic reticulum stress#GO:0034976;catabolic process#GO:0009056;response to stimulus#GO:0050896;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000011659.3|UniProtKB=G3R7P4 G3R7P4 TENM4 PTHR11219:SF9 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;synaptic membrane adhesion#GO:0099560;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell junction organization#GO:0034330;system development#GO:0048731;anatomical structure development#GO:0048856;synapse organization#GO:0050808 cell junction#GO:0030054;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000002588.3|UniProtKB=G3QJG3 G3QJG3 PTHR15321:SF3 TUMOR SUPPRESSOR P53-BINDING PROTEIN 1 TP53-BINDING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of cell cycle phase transition#GO:1901987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;double-strand break repair via nonhomologous end joining#GO:0006303;regulation of gene expression#GO:0010468;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage checkpoint signaling#GO:0000077;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;DNA integrity checkpoint signaling#GO:0031570;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to stress#GO:0033554;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;DNA metabolic process#GO:0006259;positive regulation of macromolecule metabolic process#GO:0010604;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 membraneless organelle#GO:0043228;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;site of double-strand break#GO:0035861;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000012326.3|UniProtKB=G3RTZ9 G3RTZ9 LEAP2 PTHR21007:SF1 LIVER EXPRESSED ANTIMICROBIAL PEPTIDE 2 LIVER-EXPRESSED ANTIMICROBIAL PEPTIDE 2 GORGO|Ensembl=ENSGGOG00000007234.3|UniProtKB=G3QWC2 G3QWC2 PTHR46374:SF2 PROTEIN CBG07384 STAR-RELATED LIPID TRANSFER PROTEIN 6 GORGO|Ensembl=ENSGGOG00000025778.2|UniProtKB=G3SF91 G3SF91 PTHR11639:SF127 S100 CALCIUM-BINDING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000010106.3|UniProtKB=G3R3Q0 G3R3Q0 PTHR10037:SF209 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1I monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;action potential#GO:0001508;calcium ion transmembrane transport#GO:0070588;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of secretion by cell#GO:1903530;transmembrane transport#GO:0055085;positive regulation of secretion#GO:0051047;nervous system process#GO:0050877;positive regulation of cytosolic calcium ion concentration#GO:0007204;monoatomic cation transmembrane transport#GO:0098655;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;transmission of nerve impulse#GO:0019226;regulation of transport#GO:0051049;regulation of localization#GO:0032879;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;regulation of membrane potential#GO:0042391;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;calcium ion import#GO:0070509;regulation of exocytosis#GO:0017157;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of secretion#GO:0051046;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;system process#GO:0003008;establishment of localization#GO:0051234;transport#GO:0006810 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;neuron projection#GO:0043005 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000009404.3|UniProtKB=G3R1V9 G3R1V9 MAD2L2 PTHR11842:SF10 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000007523.3|UniProtKB=G3SAU4 G3SAU4 TUT7 PTHR12271:SF34 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE 7 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014 nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000016385.3|UniProtKB=G3RMC4 G3RMC4 HTT PTHR10170:SF10 HUNTINGTON DISEASE PROTEIN HUNTINGTIN central nervous system development#GO:0007417;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;cellular localization#GO:0051641;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;microtubule-based transport#GO:0099111;regulation of signaling#GO:0023051;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;nervous system development#GO:0007399;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;organelle localization#GO:0051640;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;vesicle localization#GO:0051648;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;neurogenesis#GO:0022008;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005 Huntington disease#P00029>Htt#P00766;Huntington disease#P00029>PolyQ Htt#P00800;Huntington disease#P00029>PolyQ HTT#G01532;Huntington disease#P00029>Truncated Htt#P00761;Huntington disease#P00029>HTT#G01530 GORGO|Ensembl=ENSGGOG00000004509.3|UniProtKB=G3QPD2 G3QPD2 ERBB2 PTHR24416:SF137 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;protein kinase activity#GO:0004672 regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;nervous system development#GO:0007399;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584 membrane#GO:0016020;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>EGFR#P00466;EGF receptor signaling pathway#P00018>EGFR#P00542 GORGO|Gene=1B03_GORGO|UniProtKB=P30381 P30381 PTHR16675:SF279 MHC CLASS I-RELATED CLASS I HISTOCOMPATIBILITY ANTIGEN, GOGO-B*0102 ALPHA CHAIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of leukocyte mediated cytotoxicity#GO:0001910;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000000881.3|UniProtKB=G3QF08 G3QF08 DIPK1A PTHR21093:SF4 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1A GORGO|Ensembl=ENSGGOG00000008237.3|UniProtKB=G3QYV6 G3QYV6 FOXR2 PTHR46789:SF2 FORKHEAD BOX PROTEIN R1 FORKHEAD BOX PROTEIN R2 double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000016826.3|UniProtKB=G3RKY6 G3RKY6 MORF4L1 PTHR10880:SF29 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;chromatin#GO:0000785;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000023239.2|UniProtKB=G3SGS5 G3SGS5 METTL25 PTHR12496:SF9 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25-RELATED RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000016493.3|UniProtKB=G3RK30 G3RK30 PTHR23349:SF10 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 9 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000039723.1|UniProtKB=A0A2I2YWJ7 A0A2I2YWJ7 LOC101149889 PTHR11595:SF21 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-DELTA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000025679.2|UniProtKB=G3S721 G3S721 PTHR31395:SF0 SHISA PROTEIN SHISA-2 HOMOLOG regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000041547.1|UniProtKB=A0A2I2YIH5 A0A2I2YIH5 PTHR19375:SF572 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK PROTEIN FAMILY A (HSP70) MEMBER 8 ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;vesicle-mediated transport#GO:0016192;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;protein-containing complex disassembly#GO:0032984;protein folding#GO:0006457;localization#GO:0051179;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;protein refolding#GO:0042026 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Hsp70 family chaperone#PC00027;chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000012430.3|UniProtKB=G3S0M3 G3S0M3 SLC26A9 PTHR11814:SF17 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 9 monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;active transmembrane transporter activity#GO:0022804;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000016161.3|UniProtKB=G3RJ88 G3RJ88 FBXL6 PTHR16134:SF28 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 6 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012106.4|UniProtKB=G3R8U2 G3R8U2 PTHR12582:SF7 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5C transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 GORGO|Ensembl=ENSGGOG00000038943.1|UniProtKB=A0A2I2ZC60 A0A2I2ZC60 UNC119B PTHR12951:SF3 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG B lipid binding#GO:0008289;binding#GO:0005488 cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;organelle assembly#GO:0070925;protein transport#GO:0015031;cilium organization#GO:0044782;localization#GO:0051179;cell projection assembly#GO:0030031;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000016526.3|UniProtKB=G3RK64 G3RK64 NME1 PTHR11349:SF69 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE A nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776 phosphorus metabolic process#GO:0006793;nucleoside triphosphate biosynthetic process#GO:0009142;metabolic process#GO:0008152;cellular process#GO:0009987;nucleoside triphosphate metabolic process#GO:0009141;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137;transferase#PC00220 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 GORGO|Ensembl=ENSGGOG00000000754.3|UniProtKB=G3RUT3 G3RUT3 APOA1BP PTHR13232:SF11 NAD(P)H-HYDRATE EPIMERASE NAD(P)H-HYDRATE EPIMERASE catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;isomerase activity#GO:0016853 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003887.3|UniProtKB=G3QMS1 G3QMS1 TRIM8 PTHR24103:SF588 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM8 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012199.3|UniProtKB=G3S722 G3S722 C2CD6 PTHR21665:SF2 CATION CHANNEL SPERM-ASSOCIATED TARGETING SUBUNIT TAU CATION CHANNEL SPERM-ASSOCIATED TARGETING SUBUNIT TAU GORGO|Ensembl=ENSGGOG00000008633.3|UniProtKB=G3RPC9 G3RPC9 KHDRBS1 PTHR11208:SF30 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 1 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000003907.3|UniProtKB=G3QMT3 G3QMT3 NUDT2 PTHR21340:SF0 DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL] pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside monophosphate metabolic process#GO:0009123;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000014082.3|UniProtKB=G3RX69 G3RX69 NECAP2 PTHR12847:SF16 ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED ADAPTIN EAR-BINDING COAT-ASSOCIATED PROTEIN 2 intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle#GO:0030136;clathrin-coated vesicle membrane#GO:0030665;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000024950.2|UniProtKB=A0A2I2YKC3 A0A2I2YKC3 PTHR11667:SF27 FAMILY NOT NAMED ADENYLATE KINASE GORGO|Ensembl=ENSGGOG00000015124.4|UniProtKB=G3RGL6 G3RGL6 DCAF13 PTHR22851:SF0 U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 13 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001925.3|UniProtKB=G3RWU2 G3RWU2 LILRB3 PTHR11738:SF187 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 6-RELATED molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of immune response#GO:0050776;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signaling#GO:0023052;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;cellular process#GO:0009987;signal transduction#GO:0007165;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000006208.3|UniProtKB=G3QTQ8 G3QTQ8 MAPK8IP3 PTHR13886:SF3 JNK/SAPK-ASSOCIATED PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 3 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900;structural molecule activity#GO:0005198;MAP kinase scaffold activity#GO:0005078;cytoskeletal protein binding#GO:0008092;protein complex scaffold activity#GO:0140378;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002425.3|UniProtKB=G3QJ09 G3QJ09 TESPA1 PTHR17469:SF1 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN TESPA1 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular component assembly#GO:0022607;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000043038.1|UniProtKB=A0A2I2Y8Z7 A0A2I2Y8Z7 PTHR11224:SF47 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012731.3|UniProtKB=G3RAE4 G3RAE4 SLX1A PTHR20208:SF10 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 GORGO|Ensembl=ENSGGOG00000024797.2|UniProtKB=G3S4H4 G3S4H4 DNAAF2 PTHR22997:SF3 PIH1 DOMAIN-CONTAINING PROTEIN 1 PROTEIN KINTOUN organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000038228.1|UniProtKB=A0A2I2ZRK4 A0A2I2ZRK4 PTHR22745:SF0 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of apoptotic process#GO:0043066;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000044178.1|UniProtKB=A0A2I2ZUU7 A0A2I2ZUU7 PLA2G12A PTHR12824:SF7 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GROUP XIIA SECRETORY PHOSPHOLIPASE A2 lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;A2-type glycerophospholipase activity#GO:0004623 lipase#PC00143;phospholipase#PC00186;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000000847.3|UniProtKB=G3S0Z9 G3S0Z9 PLXNA1 PTHR22625:SF35 PLEXIN PLEXIN-A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of axonogenesis#GO:0050770;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of axonogenesis#GO:0050772;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;signaling#GO:0023052;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;cellular developmental process#GO:0048869;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cell adhesion#GO:0007162;system development#GO:0048731;regulation of nervous system development#GO:0051960;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of cell differentiation#GO:0045597;neuron differentiation#GO:0030182;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;regulation of biological quality#GO:0065008;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;synapse assembly#GO:0007416;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;regulation of plasma membrane bounded cell projection organization#GO:0120035;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Axon guidance mediated by semaphorins#P00007>PlexinA1#P00334 GORGO|Ensembl=ENSGGOG00000013526.3|UniProtKB=G3RCH3 G3RCH3 STAC PTHR15135:SF3 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of protein localization to membrane#GO:1905475;positive regulation of biological process#GO:0048518;system process#GO:0003008;regulation of localization#GO:0032879;muscle contraction#GO:0006936;regulation of cellular process#GO:0050794;striated muscle contraction#GO:0006941;skeletal muscle contraction#GO:0003009;muscle system process#GO:0003012;regulation of biological process#GO:0050789;regulation of protein localization#GO:0032880;nervous system process#GO:0050877;neuromuscular process#GO:0050905 cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000008352.3|UniProtKB=G3QZ62 G3QZ62 FREM3 PTHR45739:SF5 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 3 cell-substrate adhesion#GO:0031589;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;cellular process#GO:0009987 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Gene=ZNF80|UniProtKB=P51503 P51503 ZNF80 PTHR23226:SF203 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 80 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000023777.2|UniProtKB=A0A2I2ZBE9 A0A2I2ZBE9 PTHR32510:SF5 TRANSMEMBRANE PROTEIN 98 TRANSMEMBRANE PROTEIN 98 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000041894.1|UniProtKB=A0A2I2Z1X2 A0A2I2Z1X2 RAP2B PTHR24070:SF194 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2B hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of locomotion#GO:0040012;intracellular signaling cassette#GO:0141124;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cell migration#GO:0030334 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 GORGO|Ensembl=ENSGGOG00000011090.3|UniProtKB=G3R686 G3R686 CACNA1E PTHR45628:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT R-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1E transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245 transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987 transporter complex#GO:1990351;cation channel complex#GO:0034703;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell body#GO:0044297;calcium channel complex#GO:0034704;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796 voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 GORGO|Ensembl=ENSGGOG00000028061.2|UniProtKB=A0A2I2ZG41 A0A2I2ZG41 SWI5 PTHR28529:SF2 DNA REPAIR PROTEIN SWI5 HOMOLOG DNA REPAIR PROTEIN SWI5 HOMOLOG recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000010759.3|UniProtKB=G3R5C7 G3R5C7 CEP70 PTHR14594:SF1 CENTROSOMAL PROTEIN OF 70 KDA CENTROSOMAL PROTEIN OF 70 KDA organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015072.3|UniProtKB=G3RZN2 G3RZN2 LOC101148918 PTHR12625:SF1 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR LIMB REGION 1 PROTEIN HOMOLOG transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002491.3|UniProtKB=G3QJ70 G3QJ70 NFKBIB PTHR47303:SF1 FAMILY NOT NAMED NF-KAPPA-B INHIBITOR BETA response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;response to molecule of bacterial origin#GO:0002237;response to bacterium#GO:0009617;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;response to other organism#GO:0051707;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;response to lipopolysaccharide#GO:0032496 GORGO|Ensembl=ENSGGOG00000010579.3|UniProtKB=A0A2I2YPH7 A0A2I2YPH7 PTK7 PTHR24416:SF573 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE 7 transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003276.3|UniProtKB=G3QL73 G3QL73 CYSLTR1 PTHR24231:SF45 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CYSTEINYL LEUKOTRIENE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Gene=PRM2|UniProtKB=P35313 P35313 PRM2 PTHR21341:SF2 PROTAMINE-2 PROTAMINE-2 cellular process#GO:0009987;organelle organization#GO:0006996;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;germ cell development#GO:0007281;cellular component organization#GO:0016043;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;gamete generation#GO:0007276;cell differentiation#GO:0030154;spermatid development#GO:0007286;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000486.3|UniProtKB=A0A2I2YMI6 A0A2I2YMI6 THOC2 PTHR21597:SF0 THO2 PROTEIN THO COMPLEX SUBUNIT 2 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;transcription export complex#GO:0000346;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000038631.1|UniProtKB=G3R130 G3R130 UPK2 PTHR17573:SF0 UROPLAKIN II UROPLAKIN-2 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cell differentiation#GO:0030154 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000016346.3|UniProtKB=G3SGT3 G3SGT3 DDO PTHR11530:SF31 D-AMINO ACID OXIDASE D-ASPARTATE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000006248.3|UniProtKB=G3QTS6 G3QTS6 GUCA1C PTHR23055:SF80 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 3 enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;cation binding#GO:0043169;molecular function activator activity#GO:0140677;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000011205.4|UniProtKB=G3R6H6 G3R6H6 FSTL4 PTHR10913:SF9 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 4 cellular process#GO:0009987;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell differentiation#GO:0030154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000008331.3|UniProtKB=A0A2I2YJD9 A0A2I2YJD9 TMEM123 PTHR11337:SF14 MUCIN/PORIMIN PORIMIN intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000000528.3|UniProtKB=G3QE35 G3QE35 SLC26A2 PTHR11814:SF16 SULFATE TRANSPORTER SULFATE TRANSPORTER carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;chloride transmembrane transporter activity#GO:0015108;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003614.3|UniProtKB=G3QM29 G3QM29 ITK PTHR24418:SF61 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ITK_TSK non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 mononuclear cell differentiation#GO:1903131;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;leukocyte activation#GO:0045321;cell development#GO:0048468;cell differentiation#GO:0030154;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;immune system process#GO:0002376;anatomical structure development#GO:0048856;cellular process#GO:0009987;T cell differentiation#GO:0030217;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;developmental process#GO:0032502;cellular developmental process#GO:0048869 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 GORGO|Ensembl=ENSGGOG00000012294.3|UniProtKB=G3R9B2 G3R9B2 BLVRB PTHR43355:SF2 FLAVIN REDUCTASE (NADPH) FLAVIN REDUCTASE (NADPH) oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000042529.1|UniProtKB=A0A2I2YED4 A0A2I2YED4 LOC101135945 PTHR12479:SF14 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4B regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of membrane permeability#GO:0090559 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001931.3|UniProtKB=G3QHR7 G3QHR7 ALKBH3 PTHR31212:SF4 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000022709.2|UniProtKB=G3S2S1 G3S2S1 RALY PTHR13968:SF6 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN RALY binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001389.3|UniProtKB=G3QDS1 G3QDS1 FER1L5 PTHR12546:SF34 FER-1-LIKE FER-1-LIKE PROTEIN 5 membrane fusion#GO:0061025;response to wounding#GO:0009611;response to stress#GO:0006950;cellular process#GO:0009987;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;muscle cell development#GO:0055001;cellular component organization#GO:0016043;muscle cell differentiation#GO:0042692;cell differentiation#GO:0030154;response to stimulus#GO:0050896;muscle structure development#GO:0061061;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;plasma membrane organization#GO:0007009;anatomical structure development#GO:0048856;wound healing#GO:0042060 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000016689.3|UniProtKB=A0A2I2ZL00 A0A2I2ZL00 MOGAT3 PTHR12317:SF36 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 3 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;biosynthetic process#GO:0009058;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;neutral lipid metabolic process#GO:0006638 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000036952.1|UniProtKB=A0A2I2ZWW0 A0A2I2ZWW0 LOC101135947 PTHR26450:SF141 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002593.3|UniProtKB=G3SDW0 G3SDW0 ARHGAP5 PTHR46005:SF2 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 5 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;regulation of cell size#GO:0008361;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;regulation of anatomical structure size#GO:0090066;regulation of axonogenesis#GO:0050770;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000000538.3|UniProtKB=G3QE45 G3QE45 ASB3 PTHR24173:SF86 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 3 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009612.3|UniProtKB=G3R2E3 G3R2E3 USP30 PTHR24006:SF888 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000025320.3|UniProtKB=G3S1N7 G3S1N7 PTHR12214:SF4 GC-RICH SEQUENCE DNA-BINDING FACTOR INTRON LARGE COMPLEX COMPONENT GCFC2 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000016482.3|UniProtKB=G3RK22 G3RK22 ISG20L2 PTHR12801:SF78 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED INTERFERON-STIMULATED 20 KDA EXONUCLEASE-LIKE 2 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 exoribonuclease#PC00099;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000040246.1|UniProtKB=A0A2I2YHH3 A0A2I2YHH3 PTHR13378:SF3 REGULATOR COMPLEX PROTEIN LAMTOR3 RAGULATOR COMPLEX PROTEIN LAMTOR3 regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;positive regulation of TORC1 signaling#GO:1904263;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027826.2|UniProtKB=A0A2I2ZN27 A0A2I2ZN27 LOC101134051 PTHR48002:SF108 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D9 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000984.3|UniProtKB=G3QFA2 G3QFA2 PTHR34253:SF2 PROTEIN LLP HOMOLOG PROTEIN LLP HOMOLOG neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;growth#GO:0040007;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell growth#GO:0016049;developmental growth#GO:0048589;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;developmental cell growth#GO:0048588;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;system development#GO:0048731 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000014552.3|UniProtKB=G3RF37 G3RF37 WDR86 PTHR44489:SF17 FAMILY NOT NAMED WD REPEAT DOMAIN 86 GORGO|Ensembl=ENSGGOG00000011851.3|UniProtKB=G3R855 G3R855 KRCC1 PTHR46742:SF3 LYSINE-RICH COILED-COIL PROTEIN 1 LYSINE-RICH COILED-COIL PROTEIN 1 GORGO|Ensembl=ENSGGOG00000034921.2|UniProtKB=A0A2I2YI84 A0A2I2YI84 RABGAP1L PTHR47219:SF7 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE RAB GTPASE-ACTIVATING PROTEIN 1-LIKE enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme binding#GO:0019899;binding#GO:0005488;molecular function activator activity#GO:0140677;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000040029.1|UniProtKB=A0A2I2YXH7 A0A2I2YXH7 PTHR10064:SF17 60S RIBOSOMAL PROTEIN L22 RPL22 RNA binding#GO:0003723;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016237.3|UniProtKB=A0A2I2ZTM7 A0A2I2ZTM7 ZNF565 PTHR24381:SF458 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 697 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000003875.3|UniProtKB=G3S3P5 G3S3P5 LOC101147010 PTHR24302:SF38 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A5 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000005523.3|UniProtKB=G3QRZ7 G3QRZ7 PRRC2A PTHR14038:SF5 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2A binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003658.3|UniProtKB=G3QM68 G3QM68 HEATR4 PTHR12697:SF20 PBS LYASE HEAT-LIKE PROTEIN HEAT REPEAT-CONTAINING PROTEIN 4 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lyase#PC00144 GORGO|Ensembl=ENSGGOG00000016329.3|UniProtKB=G3RJN4 G3RJN4 APOOL PTHR14564:SF5 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005602.3|UniProtKB=G3QS58 G3QS58 GPATCH2L PTHR14195:SF3 G PATCH DOMAIN CONTAINING PROTEIN 2 G PATCH DOMAIN-CONTAINING PROTEIN 2-LIKE intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000024806.2|UniProtKB=G3S0U7 G3S0U7 TMEM60 PTHR13568:SF4 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 60 GORGO|Ensembl=ENSGGOG00000006288.4|UniProtKB=G3QTW7 G3QTW7 CMYA5 PTHR24099:SF7 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED CARDIOMYOPATHY-ASSOCIATED PROTEIN 5 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000037581.1|UniProtKB=A0A2I2ZQU9 A0A2I2ZQU9 OR1E1 PTHR48001:SF130 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1E3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000896.3|UniProtKB=G3QF21 G3QF21 CYREN PTHR14566:SF0 CELL CYCLE REGULATOR OF NON-HOMOLOGOUS END JOINING CELL CYCLE REGULATOR OF NON-HOMOLOGOUS END JOINING DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016505.3|UniProtKB=G3RK40 G3RK40 PLAAT1 PTHR13943:SF37 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 1 carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;A2-type glycerophospholipase activity#GO:0004623 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010720.3|UniProtKB=G3R583 G3R583 RSAD2 PTHR21339:SF0 RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2 S-ADENOSYLMETHIONINE-DEPENDENT NUCLEOTIDE DEHYDRATASE RSAD2 iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094 positive regulation of biological process#GO:0048518;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;response to virus#GO:0009615 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000013948.3|UniProtKB=G3SC47 G3SC47 PIP5K1B PTHR23086:SF34 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 BETA phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 kinase#PC00137;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000003948.3|UniProtKB=G3QMX4 G3QMX4 RABAC1 PTHR19317:SF0 PRENYLATED RAB ACCEPTOR 1-RELATED PRENYLATED RAB ACCEPTOR PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011142.3|UniProtKB=G3R6B8 G3R6B8 AMOT PTHR14826:SF6 ANGIOMOTIN ANGIOMOTIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cytoskeleton organization#GO:0007010;hippo signaling#GO:0035329;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;angiogenesis#GO:0001525;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell migration#GO:0016477;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;system development#GO:0048731;intracellular signal transduction#GO:0035556;actin filament-based process#GO:0030029;cell motility#GO:0048870;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;establishment of cell polarity#GO:0030010;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;cell leading edge#GO:0031252;cytoplasm#GO:0005737;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;lamellipodium#GO:0030027;apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000002814.3|UniProtKB=A0A2I2ZPX5 A0A2I2ZPX5 DAZAP1 PTHR48032:SF23 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 DAZ ASSOCIATED PROTEIN 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000176.3|UniProtKB=A0A2I2Y400 A0A2I2Y400 PODXL2 PTHR15594:SF1 PODOCALYXIN-LIKE PROTEIN 2 PODOCALYXIN-LIKE PROTEIN 2 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000010461.3|UniProtKB=G3R4K9 G3R4K9 GART PTHR10520:SF12 TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908 GORGO|Ensembl=ENSGGOG00000004459.3|UniProtKB=G3QP90 G3QP90 DNAJC2 PTHR43999:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 Hsp70 protein binding#GO:0030544;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000004925.3|UniProtKB=A0A2I2YA67 A0A2I2YA67 DLG3 PTHR23119:SF28 DISCS LARGE DISKS LARGE HOMOLOG 3 structural constituent of synapse#GO:0098918;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;binding#GO:0005488;structural molecule activity#GO:0005198 cellular process#GO:0009987;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;nervous system development#GO:0007399;multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;signaling#GO:0023052;cell adhesion#GO:0007155;receptor clustering#GO:0043113;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular protein localization#GO:0008104;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;establishment or maintenance of bipolar cell polarity#GO:0061245;localization within membrane#GO:0051668;trans-synaptic signaling#GO:0099537;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to cell junction#GO:1902414;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;neuromuscular junction#GO:0031594;cell junction#GO:0030054;synaptic membrane#GO:0097060 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000017177.3|UniProtKB=G3RLV3 G3RLV3 PTHR45656:SF6 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 2 postsynapse organization#GO:0099173;excitatory synapse assembly#GO:1904861;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;system development#GO:0048731;postsynaptic specialization organization#GO:0099084;anatomical structure development#GO:0048856;synapse organization#GO:0050808;postsynaptic density organization#GO:0097106;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cellular process#GO:0009987;postsynaptic density assembly#GO:0097107;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;glutamatergic synapse#GO:0098978;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794 GORGO|Ensembl=ENSGGOG00000026955.2|UniProtKB=A0A2I2YN14 A0A2I2YN14 FCER1G PTHR16803:SF0 HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR GAMMA-SUBUNIT HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT GAMMA molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular process#GO:0009987;defense response to other organism#GO:0098542;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;immune system process#GO:0002376;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;adaptive immune response#GO:0002250;response to other organism#GO:0051707;regulation of response to stimulus#GO:0048583;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of immune response#GO:0050776;cell communication#GO:0007154 external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000028369.2|UniProtKB=A0A2I2Z408 A0A2I2Z408 PTHR11991:SF12 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;regulation of metabolic process#GO:0019222;negative regulation of cell communication#GO:0010648;negative regulation of catabolic process#GO:0009895;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000001215.3|UniProtKB=G3QFW5 G3QFW5 ADAMDEC1 PTHR11905:SF125 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM DEC1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000041368.1|UniProtKB=A0A2I2YKB2 A0A2I2YKB2 TSR2 PTHR21250:SF0 PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007499.3|UniProtKB=G3QX13 G3QX13 SLC35D2 PTHR11132:SF262 SOLUTE CARRIER FAMILY 35 NUCLEOTIDE SUGAR TRANSPORTER SLC35D2 carboxylic acid transmembrane transporter activity#GO:0046943;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 nucleotide-sugar transmembrane transport#GO:0015780;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000038583.1|UniProtKB=A0A2I2ZDL8 A0A2I2ZDL8 C2H3orf62 PTHR36680:SF1 HYPOTHETICAL LOC498675 CHROMOSOME 3 OPEN READING FRAME 62 GORGO|Ensembl=ENSGGOG00000001374.3|UniProtKB=G3QGA6 G3QGA6 TSTD2 PTHR43268:SF6 THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2 THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000008391.3|UniProtKB=G3QZ97 G3QZ97 RAD18 PTHR14134:SF2 E3 UBIQUITIN-PROTEIN LIGASE RAD18 E3 UBIQUITIN-PROTEIN LIGASE RAD18 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012267.3|UniProtKB=G3R986 G3R986 MCFD2 PTHR23104:SF14 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006003.3|UniProtKB=G3RVD7 G3RVD7 INPP4A PTHR12187:SF4 AGAP000124-PA INOSITOL POLYPHOSPHATE-4-PHOSPHATASE TYPE I A hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;regulation of intracellular signal transduction#GO:1902531;regulation of biological quality#GO:0065008;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 postsynaptic density#GO:0014069;cell junction#GO:0030054;membrane#GO:0016020;postsynapse#GO:0098794;neuron to neuron synapse#GO:0098984;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000023113.2|UniProtKB=A0A2I2Z0G0 A0A2I2Z0G0 PTHR10693:SF50 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN NTF2 DOMAIN-CONTAINING PROTEIN DNA helicase activity#GO:0003678;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;binding#GO:0005488;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA binding#GO:0003723;nucleic acid binding#GO:0003676 cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010254.3|UniProtKB=G3R423 G3R423 CFAP58 PTHR32083:SF31 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 58 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000014312.3|UniProtKB=G3REH1 G3REH1 PDCD1 PTHR15264:SF2 PROGRAMMED CELL DEATH PROTEIN 1 PROGRAMMED CELL DEATH PROTEIN 1 regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 GORGO|Ensembl=ENSGGOG00000007881.3|UniProtKB=G3QXY6 G3QXY6 ODF4 PTHR10671:SF94 EPITHELIAL MEMBRANE PROTEIN-RELATED OUTER DENSE FIBER PROTEIN 4 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000015894.3|UniProtKB=G3RIJ7 G3RIJ7 HCRTR1 PTHR24241:SF30 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OREXIN_HYPOCRETIN RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000005415.3|UniProtKB=G3QRQ3 G3QRQ3 EXOC2 PTHR13043:SF1 EXOCYST COMPLEX COMPONENT SEC5 EXOCYST COMPLEX COMPONENT 2 exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;exocyst#GO:0000145;cell periphery#GO:0071944;cell cortex#GO:0005938 Ras Pathway#P04393>Sec5#P04545 GORGO|Ensembl=ENSGGOG00000004890.3|UniProtKB=G3QQC9 G3QQC9 G6PD PTHR23429:SF23 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;glucose-6-phosphate dehydrogenase activity#GO:0004345 pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;pentose-phosphate shunt, oxidative branch#GO:0009051;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;nucleobase-containing small molecule metabolic process#GO:0055086;glucose metabolic process#GO:0006006;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000005397.3|UniProtKB=G3QRM5 G3QRM5 SERPINH1 PTHR11461:SF27 SERINE PROTEASE INHIBITOR, SERPIN SERPIN H1 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;external encapsulating structure organization#GO:0045229 extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000024272.2|UniProtKB=G3SK05 G3SK05 PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3B enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000004402.3|UniProtKB=G3QP41 G3QP41 FAT1 PTHR24025:SF25 DESMOGLEIN FAMILY MEMBER CADHERIN-RELATED FAMILY MEMBER 1 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000044056.1|UniProtKB=A0A2I2ZEC0 A0A2I2ZEC0 LOC101150979 PTHR24242:SF248 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 9A2 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016525.3|UniProtKB=A0A2I2ZDD9 A0A2I2ZDD9 NLN PTHR11804:SF44 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED NEUROLYSIN, MITOCHONDRIAL catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000009457.4|UniProtKB=G3R206 G3R206 SART1 PTHR14152:SF5 SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribosome biogenesis#GO:0042254;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;ribonucleoprotein complex biogenesis#GO:0022613;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000004841.3|UniProtKB=G3S2R6 G3S2R6 MICU1 PTHR12294:SF1 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;mitochondrial calcium ion homeostasis#GO:0051560;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;transporter complex#GO:1990351;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;calcium channel complex#GO:0034704;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000022719.2|UniProtKB=G3RQH7 G3RQH7 LRFN5 PTHR24366:SF29 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 5 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000038463.1|UniProtKB=A0A2I2ZDM9 A0A2I2ZDM9 PTHR12138:SF149 PRIMATE-EXPANDED PROTEIN FAMILY SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000010950.3|UniProtKB=G3R5T5 G3R5T5 SH2D7 PTHR14388:SF6 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 7 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000034838.2|UniProtKB=G3SKU1 G3SKU1 ATXN10 PTHR13255:SF1 ATAXIN-10 ATAXIN-10 multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;cilium assembly#GO:0060271;anatomical structure development#GO:0048856;neuron development#GO:0048666;cilium organization#GO:0044782;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;generation of neurons#GO:0048699 cytosol#GO:0005829;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000015383.3|UniProtKB=G3SBI5 G3SBI5 ARNT PTHR23042:SF50 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 Hypoxia response via HIF activation#P00030>HIF-1beta#P00820 GORGO|Ensembl=ENSGGOG00000000586.3|UniProtKB=A0A2I2ZFL9 A0A2I2ZFL9 CCDC120 PTHR16093:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 120 FAMILY MEMBER COILED-COIL DOMAIN-CONTAINING PROTEIN 120 GORGO|Ensembl=ENSGGOG00000036211.1|UniProtKB=A0A2I2YJK6 A0A2I2YJK6 LOC109025241 PTHR11733:SF133 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000000143.3|UniProtKB=G3QD38 G3QD38 DHX8 PTHR18934:SF277 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX8 binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000041267.1|UniProtKB=A0A2I2ZQ06 A0A2I2ZQ06 AHSG PTHR13814:SF6 FETUIN ALPHA-2-HS-GLYCOPROTEIN molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 response to stress#GO:0006950;regulation of response to external stimulus#GO:0032101;regulation of bone mineralization#GO:0030500;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;defense response#GO:0006952;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;inflammatory response#GO:0006954;acute inflammatory response#GO:0002526 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000005448.3|UniProtKB=A0A2I2YR30 A0A2I2YR30 LOC101146890 PTHR19370:SF121 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 3 catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;oxidoreductase activity, acting on NAD(P)H#GO:0016651 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000016967.3|UniProtKB=G3SC81 G3SC81 CIART PTHR35441:SF1 CIRCADIAN-ASSOCIATED TRANSCRIPTIONAL REPRESSOR CIRCADIAN-ASSOCIATED TRANSCRIPTIONAL REPRESSOR transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;rhythmic process#GO:0048511;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000011409.3|UniProtKB=A0A2I2YU85 A0A2I2YU85 LOC109027830 PTHR11431:SF37 FERRITIN FERRITIN HEAVY CHAIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826;metal ion transport#GO:0030001 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000017078.3|UniProtKB=G3RLM1 G3RLM1 ACACA PTHR45728:SF5 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE 1 catalytic activity#GO:0003824;ligase activity#GO:0016874 monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000004957.3|UniProtKB=G3S3R7 G3S3R7 COQ8B PTHR43851:SF4 FAMILY NOT NAMED ATYPICAL KINASE COQ8B, MITOCHONDRIAL small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180 GORGO|Ensembl=ENSGGOG00000008035.3|UniProtKB=G3S2I7 G3S2I7 LOC101133169 PTHR47966:SF67 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED NAPSIN-A aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protease#PC00190;aspartic protease#PC00053 GORGO|Ensembl=ENSGGOG00000012754.3|UniProtKB=G3RS10 G3RS10 TXNRD1 PTHR48105:SF7 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN REDUCTASE 1, CYTOPLASMIC disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000003108.3|UniProtKB=G3QKS4 G3QKS4 UGT3A2 PTHR48043:SF24 EG:EG0003.4 PROTEIN-RELATED UDP-GLYCOSYLTRANSFERASE 3A2 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;hexosyltransferase activity#GO:0016758 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000017014.3|UniProtKB=A0A2I2YWP4 A0A2I2YWP4 FZD10 PTHR11309:SF86 FRIZZLED FRIZZLED-10 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147 canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;non-canonical Wnt signaling pathway#GO:0035567;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 GORGO|Ensembl=ENSGGOG00000013276.3|UniProtKB=G3RBT8 G3RBT8 SGSH PTHR43108:SF6 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-SULPHOGLUCOSAMINE SULPHOHYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;aminoglycan metabolic process#GO:0006022;glycosaminoglycan catabolic process#GO:0006027;protein catabolic process#GO:0030163;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;primary metabolic process#GO:0044238;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000039037.1|UniProtKB=A0A2I2YC35 A0A2I2YC35 LOC101144095 PTHR12119:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C CYTOCHROME B-C1 COMPLEX SUBUNIT 8 metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex III#GO:0045275;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000002804.3|UniProtKB=A0A2I2Y3N3 A0A2I2Y3N3 NDUFS7 PTHR11995:SF24 NADH DEHYDROGENASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;electron transfer activity#GO:0009055;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;NADH dehydrogenase activity#GO:0003954 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;cellular respiration#GO:0045333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000036190.1|UniProtKB=A0A2I2ZKR8 A0A2I2ZKR8 LIMD2 PTHR24206:SF103 OS06G0237300 PROTEIN LIM DOMAIN-CONTAINING PROTEIN 2 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000027820.2|UniProtKB=G3SIJ8 G3SIJ8 FXYD3 PTHR14132:SF11 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 3 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transmembrane transport#GO:0034765;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of transport#GO:0051050;regulation of transmembrane transport#GO:0034762;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000043839.1|UniProtKB=A0A2I2Y732 A0A2I2Y732 LOC101131372 PTHR38650:SF4 KITA-KYUSHU LUNG CANCER ANTIGEN 1 CANCER_TESTIS ANTIGEN 83 GORGO|Ensembl=ENSGGOG00000017143.3|UniProtKB=G3RLS1 G3RLS1 ZC3HAV1L PTHR47621:SF1 ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1-LIKE ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1-LIKE GORGO|Ensembl=ENSGGOG00000023861.2|UniProtKB=G3SF93 G3SF93 CENPA PTHR45810:SF14 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000013447.3|UniProtKB=G3RC89 G3RC89 NANOS2 PTHR12887:SF10 NANOS PROTEIN NANOS HOMOLOG 2 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 oogenesis#GO:0048477;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;negative regulation of translation#GO:0017148;negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;reproductive process#GO:0022414;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006 cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004791.3|UniProtKB=G3QQ41 G3QQ41 FAM135A PTHR12482:SF40 LIPASE ROG1-RELATED-RELATED PROTEIN FAM135A hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000022734.2|UniProtKB=G3SKC8 G3SKC8 LOC101150369 PTHR10015:SF282 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK TRANSCRIPTION FACTOR, X-LINKED helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000007835.3|UniProtKB=G3S9J1 G3S9J1 TSPAN33 PTHR19282:SF154 TETRASPANIN TETRASPANIN-33 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003249.3|UniProtKB=G3QL54 G3QL54 PRKAG3 PTHR13780:SF31 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-3 nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;cation binding#GO:0043169;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166 cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of carbohydrate biosynthetic process#GO:0043255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of carbohydrate metabolic process#GO:0006109;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cellular response to glucose starvation#GO:0042149;regulation of primary metabolic process#GO:0080090;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000006718.3|UniProtKB=G3QV14 G3QV14 PTHR11636:SF68 POU DOMAIN POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000022126.2|UniProtKB=G3RMJ2 G3RMJ2 PTHR12416:SF8 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN FCF1 HOMOLOG rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000013255.3|UniProtKB=G3RBR8 G3RBR8 MICU2 PTHR12294:SF3 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 2, MITOCHONDRIAL metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;metal ion transport#GO:0030001 cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090;transporter complex#GO:1990351;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000001649.3|UniProtKB=G3QH07 G3QH07 MRPL52 PTHR34090:SF1 39S RIBOSOMAL PROTEIN L52, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML52 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000008883.3|UniProtKB=G3R0J7 G3R0J7 MPV17L2 PTHR11266:SF8 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001089.3|UniProtKB=G3QFJ9 G3QFJ9 SMARCD3 PTHR13844:SF5 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 3 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ATPase complex#GO:1904949;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000040098.1|UniProtKB=A0A2I2YD51 A0A2I2YD51 CCR6 PTHR10489:SF611 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 6 cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 mononuclear cell migration#GO:0071674;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of biological quality#GO:0065008;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of response to external stimulus#GO:0032103;positive regulation of immune system process#GO:0002684;lymphocyte migration#GO:0072676;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;taxis#GO:0042330;intracellular signaling cassette#GO:0141124;chemotaxis#GO:0006935;positive regulation of chemotaxis#GO:0050921;regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte migration#GO:0002685;locomotion#GO:0040011;leukocyte migration#GO:0050900;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000010802.3|UniProtKB=G3R5G3 G3R5G3 HACL1 PTHR43710:SF2 2-HYDROXYACYL-COA LYASE 2-HYDROXYACYL-COA LYASE 1 cation binding#GO:0043169;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 lyase#PC00144;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000058.3|UniProtKB=G3QCV8 G3QCV8 LRRK1 PTHR16083:SF95 LEUCINE RICH REPEAT CONTAINING PROTEIN RAS SUPPRESSOR PROTEIN 1 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000042159.1|UniProtKB=A0A2I2ZHP7 A0A2I2ZHP7 PTHR24006:SF768 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000017131.3|UniProtKB=G3RLQ6 G3RLQ6 TOM1L1 PTHR13856:SF28 VHS DOMAIN CONTAINING PROTEIN FAMILY TOM1-LIKE PROTEIN 1 clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000015895.3|UniProtKB=G3RIK2 G3RIK2 BAP1 PTHR10589:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE BAP1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012052.3|UniProtKB=G3R8P0 G3R8P0 CDC42SE2 PTHR13502:SF4 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR PROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000023512.2|UniProtKB=G3S9D2 G3S9D2 LYL1 PTHR13864:SF6 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED PROTEIN LYL-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000016151.3|UniProtKB=G3RYX5 G3RYX5 IFT52 PTHR12969:SF7 NGD5/OSM-6/IFT52 INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intraciliary transport particle B#GO:0030992;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000042783.1|UniProtKB=A0A2I2ZJA9 A0A2I2ZJA9 PTHR23267:SF407 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 2-14-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000042752.1|UniProtKB=A0A2I2YN71 A0A2I2YN71 PTHR13080:SF11 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED SUBFAMILY NOT NAMED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637 respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;proton-transporting ATP synthase complex#GO:0045259;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000010540.3|UniProtKB=A0A2I2YSX1 A0A2I2YSX1 NLRP7 PTHR45690:SF20 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 7 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of response to external stimulus#GO:0032101;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000002619.3|UniProtKB=A0A2I2YQW2 A0A2I2YQW2 SLC44A2 PTHR12385:SF34 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000007699.3|UniProtKB=G3QXJ2 G3QXJ2 CRYBG2 PTHR11818:SF50 BETA/GAMMA CRYSTALLIN BETA_GAMMA CRYSTALLIN DOMAIN-CONTAINING PROTEIN 2 structural molecule activity#GO:0005198 system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception of light stimulus#GO:0050953;system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;multicellular organismal process#GO:0032501;sensory system development#GO:0048880 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000017041.3|UniProtKB=G3RLI3 G3RLI3 TCFL5 PTHR15402:SF3 TRANSCRIPTION FACTOR-LIKE 5 PROTEIN TRANSCRIPTION FACTOR-LIKE 5 PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000007390.3|UniProtKB=G3QWR9 G3QWR9 PTHR10201:SF21 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-17 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141 GORGO|Ensembl=ENSGGOG00000009534.3|UniProtKB=G3R272 G3R272 GALK1 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;metabolic process#GO:0008152;hexose metabolic process#GO:0019318;monosaccharide metabolic process#GO:0005996;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 transferase#PC00220;carbohydrate kinase#PC00065;metabolite interconversion enzyme#PC00262;kinase#PC00137 Fructose galactose metabolism#P02744>Galactokinase#P02960 GORGO|Ensembl=ENSGGOG00000003440.3|UniProtKB=G3QLM7 G3QLM7 RALGDS PTHR23113:SF35 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 Ras Pathway#P04393>RalGDS#P04551 GORGO|Ensembl=ENSGGOG00000003105.3|UniProtKB=G3QKS1 G3QKS1 ZDHHC16 PTHR12246:SF28 PALMITOYLTRANSFERASE ZDHHC16 PALMITOYLTRANSFERASE ZDHHC16 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 heart development#GO:0007507;circulatory system development#GO:0072359;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;system development#GO:0048731;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;developmental process#GO:0032502;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;animal gross anatomical part developmental process#GO:0160108 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004863.3|UniProtKB=G3QQA4 G3QQA4 CCDC63 PTHR21694:SF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 GORGO|Ensembl=ENSGGOG00000008784.3|UniProtKB=G3R0A7 G3R0A7 GALNT11 PTHR11675:SF10 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 11 protein binding#GO:0005515;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;signaling receptor binding#GO:0005102;binding#GO:0005488;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 regulation of response to stimulus#GO:0048583;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000013718.3|UniProtKB=G3RCZ3 G3RCZ3 GPR143 PTHR15177:SF2 G-PROTEIN COUPLED RECEPTOR 143 G PROTEIN-COUPLED RECEPTOR 143 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;amino acid binding#GO:0016597;cation binding#GO:0043169;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;ion binding#GO:0043167;neuropeptide receptor activity#GO:0008188 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell communication#GO:0007154;pigmentation#GO:0043473;G protein-coupled receptor signaling pathway#GO:0007186;cellular pigmentation#GO:0033059;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;melanosome organization#GO:0032438 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;apical plasma membrane#GO:0016324;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;apical part of cell#GO:0045177;plasma membrane#GO:0005886;melanosome#GO:0042470;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000006301.3|UniProtKB=G3QTX7 G3QTX7 B4GALNT1 PTHR15046:SF1 GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN BETA-1,4 N-ACETYLGALACTOSAMINYLTRANSFERASE 1 acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 ceramide metabolic process#GO:0006672;glycolipid biosynthetic process#GO:0009247;glycosphingolipid biosynthetic process#GO:0006688;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 GORGO|Ensembl=ENSGGOG00000025674.2|UniProtKB=G3S7I6 G3S7I6 ARMH2 PTHR37679:SF1 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000004059.3|UniProtKB=G3QN79 G3QN79 LOC101143267 PTHR10662:SF15 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 5 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000016355.3|UniProtKB=G3RJQ9 G3RJQ9 LRRC39 PTHR48051:SF2 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 39 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000024768.2|UniProtKB=G3SEF2 G3SEF2 PTHR23268:SF91 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 12-5 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000042705.1|UniProtKB=A0A2I2Y843 A0A2I2Y843 PTHR23316:SF63 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024598.2|UniProtKB=A0A2I2Z0W8 A0A2I2Z0W8 RGN PTHR10907:SF54 REGUCALCIN REGUCALCIN hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;esterase#PC00097 GORGO|Ensembl=ENSGGOG00000009158.3|UniProtKB=G3R194 G3R194 PNO1 PTHR12826:SF13 RIBONUCLEASE Y RNA-BINDING PROTEIN PNO1 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000016573.3|UniProtKB=G3RKA4 G3RKA4 PTHR21622:SF5 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 CHCH DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036 metabolic process#GO:0008152;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;mitochondrial protein import pathway#GO:7770058;biosynthetic process#GO:0009058;localization#GO:0051179;cellular localization#GO:0051641;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;mitochondrial transport#GO:0006839 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740 GORGO|Ensembl=ENSGGOG00000006768.3|UniProtKB=G3QV53 G3QV53 SYCN PTHR17503:SF0 SYNCOLLIN SYNCOLLIN GORGO|Ensembl=ENSGGOG00000001452.3|UniProtKB=A0A2I2Y598 A0A2I2Y598 TSNAXIP1 PTHR16306:SF0 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000006767.3|UniProtKB=G3QV67 G3QV67 ARHGAP21 PTHR23175:SF16 PDZ DOMAIN-CONTAINING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 21 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;organelle transport along microtubule#GO:0072384;endomembrane system organization#GO:0010256;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;cellular localization#GO:0051641;localization#GO:0051179;Golgi organization#GO:0007030;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656 membraneless organelle#GO:0043228;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 GORGO|Ensembl=ENSGGOG00000026854.2|UniProtKB=G3SEI0 G3SEI0 PTHR23267:SF528 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 6-21-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000006991.3|UniProtKB=G3QVR0 G3QVR0 FCER2 PTHR22802:SF325 C-TYPE LECTIN SUPERFAMILY MEMBER LOW AFFINITY IMMUNOGLOBULIN EPSILON FC RECEPTOR carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000003031.3|UniProtKB=G3QKK4 G3QKK4 EHD3 PTHR11216:SF67 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein localization to membrane#GO:0072657;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;endocytosis#GO:0006897;organelle assembly#GO:0070925;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197 bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;recycling endosome#GO:0055037;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013455.3|UniProtKB=G3RC96 G3RC96 KCNJ14 PTHR11767:SF40 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 14 monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000009368.3|UniProtKB=G3R1S2 G3R1S2 GLIS1 PTHR45718:SF3 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLIS1 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000044059.1|UniProtKB=A0A2I2YFW8 A0A2I2YFW8 PTCHD1 PTHR10796:SF36 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 1 system process#GO:0003008;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;cognition#GO:0050890 membrane#GO:0016020;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000015950.3|UniProtKB=G3RIQ0 G3RIQ0 PLEKHG4 PTHR45845:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PURATROPHIN-1 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000038856.1|UniProtKB=A0A2I2YQE6 A0A2I2YQE6 PTHR47960:SF11 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 RNA HELICASE mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;cytoplasmic stress granule assembly#GO:0034063;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;membraneless organelle assembly#GO:0140694;negative regulation of biological process#GO:0048519;P-body assembly#GO:0033962;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;negative regulation of translation#GO:0017148;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008241.3|UniProtKB=G3QYW3 G3QYW3 MS4A5 PTHR23320:SF54 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 5 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000000980.3|UniProtKB=A0A2I2Z6T4 A0A2I2Z6T4 SPMIP5 PTHR47301:SF1 HYPOTHETICAL PROTEIN LOC681006 SPERM-ASSOCIATED MICROTUBULE INNER PROTEIN 5 GORGO|Ensembl=ENSGGOG00000005984.3|UniProtKB=G3QT44 G3QT44 MCCD1 PTHR37877:SF1 MITOCHONDRIAL COILED-COIL DOMAIN PROTEIN 1 MITOCHONDRIAL COILED-COIL DOMAIN PROTEIN 1 GORGO|Ensembl=ENSGGOG00000012133.3|UniProtKB=G3R8X2 G3R8X2 INTS7 PTHR13322:SF2 C1ORF73 PROTEIN INTEGRATOR COMPLEX SUBUNIT 7 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;catabolic process#GO:0009056;DNA-templated transcription#GO:0006351;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleobase-containing compound catabolic process#GO:0034655;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180 intracellular organelle#GO:0043229;integrator complex#GO:0032039;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000042533.1|UniProtKB=A1YER7 A1YER7 HOXD4 PTHR45771:SF5 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-D4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;skeletal system morphogenesis#GO:0048705;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regionalization#GO:0003002;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;skeletal system development#GO:0001501;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;anterior/posterior pattern specification#GO:0009952;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000012459.3|UniProtKB=G3R9R3 G3R9R3 C3H4orf17 PTHR33772:SF2 THYMUS, BRAIN AND TESTES-ASSOCIATED RIKEN CDNA 4930579F01 GENE GORGO|Ensembl=ENSGGOG00000043836.1|UniProtKB=A0A2I2Y6T7 A0A2I2Y6T7 PTHR12692:SF4 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED MAGNESIUM TRANSPORTER PROTEIN 1 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;monoatomic cation transmembrane transport#GO:0098655;biosynthetic process#GO:0009058;monoatomic ion transmembrane transport#GO:0034220;glycoprotein metabolic process#GO:0009100;transport#GO:0006810;metabolic process#GO:0008152;magnesium ion transport#GO:0015693;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;establishment of localization#GO:0051234;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000016018.3|UniProtKB=A0A2I2Z9V1 A0A2I2Z9V1 CHI3L2 PTHR11177:SF82 CHITINASE CHITINASE-3-LIKE PROTEIN 2 catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000027600.2|UniProtKB=G3RT82 G3RT82 LOC101131829 PTHR23175:SF20 PDZ DOMAIN-CONTAINING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 21 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 Golgi organization#GO:0007030;cellular component organization#GO:0016043;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000294.3|UniProtKB=A0A2I2ZU67 A0A2I2ZU67 ARF4 PTHR11711:SF110 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 4 guanyl nucleotide binding#GO:0019001;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 GORGO|Ensembl=ENSGGOG00000041791.1|UniProtKB=A0A2I2YZQ2 A0A2I2YZQ2 SNX21 PTHR20939:SF10 SORTING NEXIN 20, 21 SORTING NEXIN-21 phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;early endosome membrane#GO:0031901;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027275.2|UniProtKB=G3RNE9 G3RNE9 SPACA1 PTHR47223:SF1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 1 cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;vesicle organization#GO:0016050;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;spermatogenesis#GO:0007283;male gamete generation#GO:0048232;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;spermatid differentiation#GO:0048515;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;spermatid development#GO:0007286;acrosome assembly#GO:0001675;sexual reproduction#GO:0019953;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;germ cell development#GO:0007281;anatomical structure morphogenesis#GO:0009653 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;acrosomal membrane#GO:0002080;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004431.3|UniProtKB=G3QP61 G3QP61 NAT2 PTHR11786:SF6 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 2 N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000006008.3|UniProtKB=G3SBW6 G3SBW6 PIN1 PTHR10657:SF31 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000003972.3|UniProtKB=G3QMZ7 G3QMZ7 FOXA3 PTHR11829:SF201 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-GAMMA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000040712.1|UniProtKB=A0A2I2YW75 A0A2I2YW75 C18H16orf82 PTHR40139:SF1 PROTEIN TNT PROTEIN TNT GORGO|Ensembl=ENSGGOG00000012878.3|UniProtKB=A0A2I2ZLJ9 A0A2I2ZLJ9 POLD3 PTHR17598:SF13 DNA POLYMERASE DELTA SUBUNIT 3 DNA POLYMERASE DELTA SUBUNIT 3 DNA-directed DNA polymerase activity#GO:0003887;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;DNA strand elongation involved in DNA replication#GO:0006271;cellular response to radiation#GO:0071478;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;response to UV#GO:0009411;DNA damage response#GO:0006974;cellular response to abiotic stimulus#GO:0071214;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to radiation#GO:0009314;macromolecule biosynthetic process#GO:0009059;cellular response to light stimulus#GO:0071482;DNA biosynthetic process#GO:0071897;nucleotide-excision repair#GO:0006289;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;replisome#GO:0030894;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000022950.2|UniProtKB=G3SDX4 G3SDX4 MPV17 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000041029.1|UniProtKB=A0A2I2Y861 A0A2I2Y861 EPGN PTHR10740:SF10 TRANSFORMING GROWTH FACTOR ALPHA EPIGEN binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of cell cycle#GO:0045787;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of mitotic cell cycle#GO:0007346;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of mitotic nuclear division#GO:0007088;cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 GORGO|Ensembl=ENSGGOG00000013564.3|UniProtKB=G3RCJ7 G3RCJ7 TUT1 PTHR12271:SF127 POLY A POLYMERASE CID PAP -RELATED SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640 negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membraneless organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000014396.3|UniProtKB=G3RUS2 G3RUS2 PHLDA2 PTHR15478:SF15 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 2 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;placenta development#GO:0001890 GORGO|Ensembl=ENSGGOG00000010331.3|UniProtKB=G3R487 G3R487 LNP1 PTHR35667:SF1 LEUKEMIA NUP98 FUSION PARTNER 1 LEUKEMIA NUP98 FUSION PARTNER 1 GORGO|Ensembl=ENSGGOG00000014917.3|UniProtKB=G3RG17 G3RG17 XKR8 PTHR16024:SF8 XK-RELATED PROTEIN XK-RELATED PROTEIN 8 cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane invagination#GO:0010324;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cellular component organization#GO:0016043;endocytosis#GO:0006897;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;developmental process#GO:0032502;transport#GO:0006810;phagocytosis#GO:0006909;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cell death#GO:0008219;programmed cell death#GO:0012501;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;localization#GO:0051179;anatomical structure development#GO:0048856 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000006193.3|UniProtKB=G3QTN0 G3QTN0 LOC101147034 PTHR11430:SF124 LIPOCALIN LIPOCALIN 1-LIKE PROTEIN 1-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000005708.3|UniProtKB=A0A2I2YLK1 A0A2I2YLK1 CNIH4 PTHR12290:SF19 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 4 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000025803.2|UniProtKB=A0A2I2ZXE9 A0A2I2ZXE9 LOC101141131 PTHR23115:SF222 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 1-RELATED translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000006590.3|UniProtKB=G3QUP8 G3QUP8 LCP2 PTHR14098:SF1 SH2 DOMAIN CONTAINING PROTEIN LYMPHOCYTE CYTOSOLIC PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 immune system process#GO:0002376;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell activation#GO:0001775;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular signal transduction#GO:0035556;leukocyte activation#GO:0045321;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;myeloid leukocyte activation#GO:0002274;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 T cell activation#P00053>SLP-76#P01321 GORGO|Ensembl=ENSGGOG00000036205.1|UniProtKB=A0A2I2YQI2 A0A2I2YQI2 PTHR23237:SF9 NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515 RNA biosynthetic process#GO:0032774;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;telomere organization#GO:0032200;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;RNA-templated DNA biosynthetic process#GO:0006278;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;telomere maintenance via telomere lengthening#GO:0010833;gene expression#GO:0010467;telomere maintenance via telomerase#GO:0007004;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013180.3|UniProtKB=G3RBK4 G3RBK4 STT3B PTHR13872:SF49 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein modification process#GO:0036211;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238 membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000036293.1|UniProtKB=A0A2I2YRP7 A0A2I2YRP7 FGF12 PTHR11486:SF17 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 12 signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;ion channel regulator activity#GO:0099106;receptor ligand activity#GO:0048018;fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;transporter regulator activity#GO:0141108;protein binding#GO:0005515;channel regulator activity#GO:0016247;molecular function activator activity#GO:0140677 multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000008356.3|UniProtKB=G3QZ73 G3QZ73 NCKAP1L PTHR12093:SF9 NCK-ASSOCIATED PROTEIN 1 NCK-ASSOCIATED PROTEIN 1-LIKE plasma membrane bounded cell projection organization#GO:0120036;cell migration#GO:0016477;multicellular organismal process#GO:0032501;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;system development#GO:0048731;anatomical structure development#GO:0048856;cortical actin cytoskeleton organization#GO:0030866;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000041656.1|UniProtKB=A0A2I2ZD79 A0A2I2ZD79 PTHR45789:SF5 FI18025P1 HMG BOX DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000004054.3|UniProtKB=G3QN72 G3QN72 RNF20 PTHR23163:SF2 RING FINGER PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE BRE1A ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007239.3|UniProtKB=A0A2I2YC37 A0A2I2YC37 PAK2 PTHR45832:SF21 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE Ras Pathway#P04393>PAK#P04553;Angiogenesis#P00005>PAK#P00249;T cell activation#P00053>PAK#P01319;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517 GORGO|Ensembl=ENSGGOG00000043396.1|UniProtKB=G3S7M4 G3S7M4 GSTM1 PTHR11571:SF247 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 1 catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000027034.2|UniProtKB=A0A2I2ZAL7 A0A2I2ZAL7 PTHR22812:SF145 CHROMOBOX PROTEIN CHROMO DOMAIN-CONTAINING PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;heterochromatin organization#GO:0070828;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523 chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000015458.3|UniProtKB=G3RHG1 G3RHG1 ABHD10 PTHR16138:SF7 MYCOPHENOLIC ACID ACYL-GLUCURONIDE ESTERASE, MITOCHONDRIAL PALMITOYL-PROTEIN THIOESTERASE ABHD10, MITOCHONDRIAL hydrolase activity#GO:0016787;palmitoyl hydrolase activity#GO:0098599;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 esterase#PC00097;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006059.3|UniProtKB=G3QTB4 G3QTB4 RABL3 PTHR24073:SF128 DRAB5-RELATED RAB-LIKE PROTEIN 3 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000038885.1|UniProtKB=A0A2I2YPP8 A0A2I2YPP8 AP5B1 PTHR34033:SF1 AP-5 COMPLEX SUBUNIT BETA-1 AP-5 COMPLEX SUBUNIT BETA-1 intracellular transport#GO:0046907;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 coated membrane#GO:0048475;membrane coat#GO:0030117;AP-type membrane coat adaptor complex#GO:0030119;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000016338.3|UniProtKB=G3RJP3 G3RJP3 PTHR12763:SF7 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY C MEMBER 15 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000024998.2|UniProtKB=G3RW50 G3RW50 CENPQ PTHR31345:SF3 CENTROMERE PROTEIN Q CENTROMERE PROTEIN Q chromosome localization#GO:0050000;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;localization#GO:0051179;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;organelle localization#GO:0051640 chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000025364.2|UniProtKB=A0A2I2YU96 A0A2I2YU96 PTHR23420:SF19 ADENOSYLHOMOCYSTEINASE S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE NAD BINDING DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;hydrolase activity#GO:0016787 amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000040884.1|UniProtKB=A0A2I2YNL5 A0A2I2YNL5 PTHR23268:SF75 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 13 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000038054.1|UniProtKB=A0A2I2YAB8 A0A2I2YAB8 C1H1orf232 PTHR35663:SF3 TESTIS DEVELOPMENT-RELATED PROTEIN-RELATED GENE, 30191-RELATED GORGO|Ensembl=ENSGGOG00000013342.3|UniProtKB=G3RBZ9 G3RBZ9 LOC101128717 PTHR45813:SF1 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F4 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000015099.3|UniProtKB=G3RGI7 G3RGI7 ANKDD1B PTHR24125:SF1 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1B GORGO|Ensembl=ENSGGOG00000008932.3|UniProtKB=G3R0N8 G3R0N8 PTHR24381:SF417 ZINC FINGER PROTEIN AA987161 PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000042168.1|UniProtKB=A4H220 A4H220 DEFB118 PTHR15001:SF7 BETA-DEFENSIN 123-RELATED DEFENSIN BETA 118 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;cellular process#GO:0009987;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;cell killing#GO:0001906 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000024047.2|UniProtKB=G3RZH2 G3RZH2 CSN2 PTHR11500:SF0 BETA CASEIN BETA-CASEIN peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 biological regulation#GO:0065007;regulation of body fluid levels#GO:0050878;regulation of biological quality#GO:0065008;secretion#GO:0046903;anatomical structure development#GO:0048856;establishment of localization#GO:0051234;animal organ development#GO:0048513;localization#GO:0051179;transport#GO:0006810;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000014886.3|UniProtKB=G3RFZ4 G3RFZ4 DNER PTHR24044:SF467 NOTCH LIGAND FAMILY MEMBER DELTA AND NOTCH-LIKE EPIDERMAL GROWTH FACTOR-RELATED RECEPTOR protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000027721.2|UniProtKB=G3RP95 G3RP95 PTHR13718:SF93 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008816.3|UniProtKB=G3S084 G3S084 DDX19A PTHR47958:SF93 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX19A ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386 nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058 nucleus#GO:0005634;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000025589.2|UniProtKB=A0A2I2Z348 A0A2I2Z348 PTHR10871:SF44 30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN US13 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000037643.1|UniProtKB=A0A2I2ZKT4 A0A2I2ZKT4 ALG9 PTHR11538:SF26 PHENYLALANYL-TRNA SYNTHETASE FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1 catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a rRNA#GO:0140102;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;ligase activity#GO:0016874;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;translation#GO:0006412;RNA processing#GO:0006396;gene expression#GO:0010467;rRNA base methylation#GO:0070475;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;cellular component biogenesis#GO:0044085;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;rRNA modification#GO:0000154;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000014519.3|UniProtKB=G3RF09 G3RF09 RAB27A PTHR47977:SF20 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-27A guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 positive regulation of secretion#GO:0051047;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;export from cell#GO:0140352;transport#GO:0006810;establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007 Golgi apparatus#GO:0005794;apical part of cell#GO:0045177;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;melanosome#GO:0042470;plasma membrane#GO:0005886;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular vesicle#GO:0097708;apical plasma membrane#GO:0016324;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000001133.3|UniProtKB=G3QFP0 G3QFP0 ACTB PTHR11937:SF575 ACTIN ACTIN, CYTOPLASMIC 2 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;actin filament#GO:0005884;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114 GORGO|Ensembl=ENSGGOG00000011692.3|UniProtKB=G3R7R0 G3R7R0 HNRNPAB PTHR48033:SF1 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A_B nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005978.3|UniProtKB=G3QT42 G3QT42 C1QTNF12 PTHR24019:SF12 ADIPOLIN ADIPOLIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546 regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;regulation of transmembrane transport#GO:0034762;regulation of carbohydrate biosynthetic process#GO:0043255;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;regulation of carbohydrate metabolic process#GO:0006109;negative regulation of cellular process#GO:0048523;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000006796.3|UniProtKB=A0A2I2ZVN0 A0A2I2ZVN0 KATNAL2 PTHR23074:SF78 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887 microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;sexual reproduction#GO:0019953;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000007640.3|UniProtKB=G3QXD3 G3QXD3 MRPS7 PTHR11205:SF19 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7M RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;ribosome#GO:0005840;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000015882.3|UniProtKB=G3RII6 G3RII6 HMGB2 PTHR48112:SF3 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B2 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000011591.3|UniProtKB=G3R7H5 G3R7H5 DLST PTHR43416:SF18 DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004966.3|UniProtKB=G3QQK0 G3QQK0 SLC27A1 PTHR43107:SF7 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 1 catalytic activity#GO:0003824;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;carboxylic acid transmembrane transporter activity#GO:0046943 lipid transport#GO:0006869;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000016981.3|UniProtKB=A0A2I2YCK0 A0A2I2YCK0 MIPOL1 PTHR22089:SF2 MIRROR-IMAGE POLYDACTYLY GENE 1 PROTEIN MIRROR-IMAGE POLYDACTYLY GENE 1 PROTEIN GORGO|Ensembl=ENSGGOG00000012562.3|UniProtKB=G3RA03 G3RA03 FEN1 PTHR11081:SF58 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE 1 RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;exonuclease activity#GO:0004527;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;metal ion binding#GO:0046872;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 GORGO|Ensembl=ENSGGOG00000024473.2|UniProtKB=G3RYQ2 G3RYQ2 S100A2 PTHR11639:SF59 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A2 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 cell motility#GO:0048870;cell migration#GO:0016477;endothelial cell migration#GO:0043542;cellular process#GO:0009987 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000000575.3|UniProtKB=G3RRP0 G3RRP0 DNTTIP2 PTHR21686:SF12 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000000364.3|UniProtKB=G3QDN2 G3QDN2 LMO4 PTHR24204:SF4 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;axonogenesis#GO:0007409;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;cell fate specification#GO:0001708;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of transcription by RNA polymerase II#GO:0045944;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of macromolecule metabolic process#GO:0010604;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;neuron fate commitment#GO:0048663;regulation of primary metabolic process#GO:0080090;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06682;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#P06791;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06896 GORGO|Ensembl=ENSGGOG00000014374.3|UniProtKB=G3REN6 G3REN6 FNBP4 PTHR46697:SF1 FORMIN-BINDING PROTEIN 4 FORMIN-BINDING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000003591.3|UniProtKB=G3QM06 G3QM06 SLC22A12 PTHR24064:SF205 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 12 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000041397.1|UniProtKB=G3S782 G3S782 PTHR23266:SF379 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-3 antigen binding#GO:0003823;binding#GO:0005488 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000007896.3|UniProtKB=G3QY00 G3QY00 PTHR45938:SF6 ACP24A4-RELATED WAP, KAZAL, IMMUNOGLOBULIN, KUNITZ AND NTR DOMAIN-CONTAINING PROTEIN 1 cytokine binding#GO:0019955;molecular function regulator activity#GO:0098772;transforming growth factor beta binding#GO:0050431;signaling receptor regulator activity#GO:0030545;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to transforming growth factor beta#GO:0071559;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011349.3|UniProtKB=G3R6U5 G3R6U5 PTHR12048:SF0 CCAAT-BINDING FACTOR-RELATED CCAAT_ENHANCER-BINDING PROTEIN ZETA intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000005632.3|UniProtKB=G3QS89 G3QS89 CPT1B PTHR22589:SF69 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, MUSCLE ISOFORM acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;lipid metabolic process#GO:0006629;transport#GO:0006810;establishment of localization#GO:0051234;monocarboxylic acid metabolic process#GO:0032787;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carnitine metabolic process#GO:0009437;small molecule metabolic process#GO:0044281;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000011812.4|UniProtKB=G3R827 G3R827 TAPT1 PTHR13317:SF5 TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of organelle organization#GO:0010638;regulation of cell projection assembly#GO:0060491;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344 endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;cilium#GO:0005929;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009184.3|UniProtKB=G3R1B7 G3R1B7 COPS7A PTHR15350:SF7 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 SIGNALOSOME COMPLEX SUBUNIT 7A post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000009797.3|UniProtKB=G3R2V6 G3R2V6 DESI2 PTHR12378:SF6 DESUMOYLATING ISOPEPTIDASE DEUBIQUITINASE DESI2 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000007626.3|UniProtKB=G3QXC1 G3QXC1 KCNK16 PTHR11003:SF104 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 16 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215 monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000013295.3|UniProtKB=G3RBW6 G3RBW6 HECW2 PTHR11254:SF127 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HECW2 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of developmental process#GO:0050793;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of dendrite morphogenesis#GO:0048814;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603;metabolic process#GO:0008152;regulation of cell projection organization#GO:0031344;macromolecule catabolic process#GO:0009057;biological regulation#GO:0065007;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008470.3|UniProtKB=G3QZG7 G3QZG7 KCNV1 PTHR11537:SF38 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY V MEMBER 1 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;metal ion transport#GO:0030001;action potential#GO:0001508;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000038216.1|UniProtKB=A0A2I2YAH1 A0A2I2YAH1 PTHR23267:SF539 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-9-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000042916.1|UniProtKB=A0A2I2YRX3 A0A2I2YRX3 TCEAL7 PTHR48555:SF2 TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 8-RELATED TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 7 GORGO|Ensembl=ENSGGOG00000013291.3|UniProtKB=G3QXZ3 G3QXZ3 KRT27 PTHR23239:SF120 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 27 structural molecule activity#GO:0005198 epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;skin development#GO:0043588;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009;epidermis development#GO:0008544;developmental process#GO:0032502;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109 organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000016378.3|UniProtKB=G3RJU4 G3RJU4 SCUBE3 PTHR24046:SF2 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 3 cellular developmental process#GO:0048869;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;smoothened signaling pathway#GO:0007224;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell development#GO:0048468;response to endogenous stimulus#GO:0009719;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000014684.3|UniProtKB=G3RFG2 G3RFG2 AKR1D1 PTHR11732:SF211 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER D1 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;hormone metabolic process#GO:0042445;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of biological quality#GO:0065008 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000043220.1|UniProtKB=A0A2I2Y2X1 A0A2I2Y2X1 AQP7 PTHR43829:SF15 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-7 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;passive transmembrane transporter activity#GO:0022803;carbohydrate transmembrane transporter activity#GO:0015144;channel activity#GO:0015267 carbohydrate transport#GO:0008643;transport#GO:0006810;water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;organic hydroxy compound transport#GO:0015850;fluid transport#GO:0042044;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011544.3|UniProtKB=G3R7C4 G3R7C4 LOC101135599 PTHR22802:SF345 C-TYPE LECTIN SUPERFAMILY MEMBER RERATING FAMILY MEMBER 4 pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000016121.3|UniProtKB=G3RJ48 G3RJ48 ID1 PTHR11723:SF4 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-1 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;nervous system development#GO:0007399;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000040596.1|UniProtKB=A0A2I2YW39 A0A2I2YW39 PTHR13138:SF3 PROTEIN LIN1 CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2 protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000027280.2|UniProtKB=A0A2I2Y426 A0A2I2Y426 TDRP PTHR35663:SF1 TESTIS DEVELOPMENT-RELATED PROTEIN-RELATED TESTIS DEVELOPMENT-RELATED PROTEIN developmental process involved in reproduction#GO:0003006;gamete generation#GO:0007276;male gamete generation#GO:0048232;reproductive process#GO:0022414;developmental process#GO:0032502;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;multicellular organismal reproductive process#GO:0048609 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000025984.2|UniProtKB=A0A2I2YHK4 A0A2I2YHK4 LYG2 PTHR31698:SF4 LYSOZYME G FAMILY MEMBER LYSOZYME G-LIKE PROTEIN 2 catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;lysozyme activity#GO:0003796 response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;response to external stimulus#GO:0009605;defense response#GO:0006952;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000025025.2|UniProtKB=G3S0C5 G3S0C5 LOC101152516 PTHR28554:SF1 39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML45 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001630.3|UniProtKB=G3QGZ0 G3QGZ0 PTHR12241:SF91 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL13 binding#GO:0005488;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000034940.2|UniProtKB=G3SKV3 G3SKV3 ARHGEF16 PTHR12845:SF3 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 16 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of actin filament-based process#GO:0032970;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000012587.3|UniProtKB=G3S471 G3S471 PIEZO1 PTHR13167:SF40 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836 biological regulation#GO:0065007;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;response to mechanical stimulus#GO:0009612;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;response to external stimulus#GO:0009605;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;cellular response to abiotic stimulus#GO:0071214;detection of mechanical stimulus#GO:0050982 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012371.3|UniProtKB=A0A2I2ZH01 A0A2I2ZH01 TAF11 PTHR13218:SF16 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11 transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 GORGO|Ensembl=ENSGGOG00000012269.3|UniProtKB=A0A2I2ZAS5 A0A2I2ZAS5 PTHR15124:SF16 SELENOPROTEIN W SELENOPROTEIN W cell development#GO:0048468;hemopoiesis#GO:0030097;homeostatic process#GO:0042592;myeloid cell differentiation#GO:0030099;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;cellular process#GO:0009987;multicellular organismal-level homeostasis#GO:0048871;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;homeostasis of number of cells#GO:0048872;developmental process#GO:0032502;immune system process#GO:0002376 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000007790.3|UniProtKB=G3QXR5 G3QXR5 ADA2 PTHR11409:SF39 ADENOSINE DEAMINASE ADENOSINE DEAMINASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000 primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;purine-containing compound biosynthetic process#GO:0072522;purine nucleoside metabolic process#GO:0042278;nucleoside catabolic process#GO:0009164;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;adenosine metabolic process#GO:0046085;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;purine nucleobase metabolic process#GO:0006144;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;nucleobase metabolic process#GO:0009112;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086 extracellular region#GO:0005576;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 deaminase#PC00088 GORGO|Ensembl=ENSGGOG00000008717.3|UniProtKB=G3R045 G3R045 MMP27 PTHR10201:SF115 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-27 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000024475.2|UniProtKB=A0A2I2ZIM0 A0A2I2ZIM0 LOC101129209 PTHR26453:SF635 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C7-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001263.3|UniProtKB=A0A2I2ZEZ9 A0A2I2ZEZ9 HYKK PTHR21064:SF1 AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED HYDROXYLYSINE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 GORGO|Ensembl=ENSGGOG00000011037.3|UniProtKB=G3R627 G3R627 RIOK1 PTHR45723:SF5 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000001258.3|UniProtKB=G3QFZ8 G3QFZ8 EXD2 PTHR13620:SF133 3-5 EXONUCLEASE EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;hydrolase activity#GO:0016787;DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097 response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;RNA biosynthetic process#GO:0032774;recombinational repair#GO:0000725;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070 mitochondrion#GO:0005739;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000027175.2|UniProtKB=G3RRJ2 G3RRJ2 LOC101131628 PTHR26454:SF30 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6X1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005011.3|UniProtKB=G3QQN4 G3QQN4 GSX1 PTHR24339:SF29 HOMEOBOX PROTEIN EMX-RELATED GS HOMEOBOX 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000010373.3|UniProtKB=G3R4C7 G3R4C7 FMR1 PTHR10603:SF4 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN FRAGILE X MESSENGER RIBONUCLEOPROTEIN 1 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 positive regulation of cell differentiation#GO:0045597;animal organ development#GO:0048513;regulation of mRNA metabolic process#GO:1903311;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of trans-synaptic signaling#GO:0099177;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nervous system development#GO:0051962;regulation of mRNA stability#GO:0043488;regulation of synaptic plasticity#GO:0048167;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;transport#GO:0006810;regulation of neuronal synaptic plasticity#GO:0048168;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;nucleic acid transport#GO:0050657;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;positive regulation of translation#GO:0045727;regulation of RNA metabolic process#GO:0051252;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;regulation of developmental process#GO:0050793;mRNA transport#GO:0051028;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;positive regulation of neurogenesis#GO:0050769 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;neuron projection#GO:0043005;nucleus#GO:0005634;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494 translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000002438.3|UniProtKB=G3QJ20 G3QJ20 ELL PTHR23288:SF9 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;snRNA transcription#GO:0009301;regulation of DNA-templated transcription elongation#GO:0032784;nucleic acid biosynthetic process#GO:0141187;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;biosynthetic process#GO:0009058;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000017104.3|UniProtKB=G3RLN5 G3RLN5 B3GNT4 PTHR11214:SF368 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;biosynthetic process#GO:0009058;aminoglycan biosynthetic process#GO:0006023;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000014255.3|UniProtKB=G3REC6 G3REC6 DNASE1L2 PTHR11371:SF29 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1-LIKE 2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 endodeoxyribonuclease#PC00093 GORGO|Ensembl=ENSGGOG00000003112.3|UniProtKB=G3QKS7 G3QKS7 REG1B PTHR22803:SF129 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED LITHOSTATHINE-1-BETA growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;response to nitrogen compound#GO:1901698;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell population proliferation#GO:0042127;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;response to other organism#GO:0051707;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;defense response to other organism#GO:0098542;response to chemical#GO:0042221;positive regulation of cellular process#GO:0048522;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;immune response#GO:0006955;response to stress#GO:0006950;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000014358.3|UniProtKB=G3REL6 G3REL6 ARHGAP39 PTHR45876:SF1 FI04035P RHO GTPASE-ACTIVATING PROTEIN 39 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000016188.3|UniProtKB=G3RJB5 G3RJB5 LRIG3 PTHR24366:SF65 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEATS AND IMMUNOGLOBULIN LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000001352.3|UniProtKB=G3SKB7 G3SKB7 YBX3 PTHR11544:SF14 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 3 binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 Gonadotropin-releasing hormone receptor pathway#P06664>Csda#P06797 GORGO|Ensembl=ENSGGOG00000005955.3|UniProtKB=G3QT23 G3QT23 XRCC2 PTHR46644:SF4 DNA REPAIR PROTEIN XRCC2 DNA REPAIR PROTEIN XRCC2 nucleic acid binding#GO:0003676;binding#GO:0005488;four-way junction DNA binding#GO:0000400;DNA binding#GO:0003677 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;replication fork#GO:0005657;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000038474.1|UniProtKB=A0A2I2ZEL8 A0A2I2ZEL8 ATF1 PTHR45879:SF2 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;intracellular signaling cassette#GO:0141124;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 Apoptosis signaling pathway#P00006>ATF#P00302;p38 MAPK pathway#P05918>ATF1#P06019 GORGO|Ensembl=ENSGGOG00000015850.3|UniProtKB=G3RIG7 G3RIG7 ELAC2 PTHR12553:SF49 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;mitochondrial RNA 3'-end processing#GO:0000965;tRNA 3'-end processing#GO:0042780;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000013372.3|UniProtKB=G3RC29 G3RC29 GTPBP4 PTHR45759:SF1 NUCLEOLAR GTP-BINDING PROTEIN 1 GTP-BINDING PROTEIN 4 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000005390.3|UniProtKB=G3QRM8 G3QRM8 ADK PTHR45769:SF3 ADENOSINE KINASE ADENOSINE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;nucleoside kinase activity#GO:0019206 nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000009363.3|UniProtKB=G3R1R8 G3R1R8 PBLD PTHR13774:SF17 PHENAZINE BIOSYNTHESIS PROTEIN PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011742.3|UniProtKB=G3R7V5 G3R7V5 LOC101127754 PTHR46019:SF4 BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED BPI FOLD-CONTAINING FAMILY B MEMBER 4 GORGO|Ensembl=ENSGGOG00000010177.3|UniProtKB=G3R3V0 G3R3V0 SPPL2B PTHR12174:SF39 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2B hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 endoplasmic reticulum#GO:0005783;cytoplasmic side of membrane#GO:0098562;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;lysosomal membrane#GO:0005765;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;cytoplasmic vesicle membrane#GO:0030659;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;side of membrane#GO:0098552;organelle subcompartment#GO:0031984;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;Golgi-associated vesicle membrane#GO:0030660;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum membrane#GO:0005789;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231 aspartic protease#PC00053;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000014850.3|UniProtKB=G3RFW8 G3RFW8 RRP12 PTHR21576:SF2 UNCHARACTERIZED NODULIN-LIKE PROTEIN RRP12-LIKE PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000023052.2|UniProtKB=G3RML9 G3RML9 PTHR12930:SF1 ZINC FINGER PROTEIN 183 RING FINGER PROTEIN 113B aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000008057.3|UniProtKB=G3QYE3 G3QYE3 NRROS PTHR45617:SF7 LEUCINE RICH REPEAT FAMILY PROTEIN TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC33 binding#GO:0005488;transforming growth factor beta binding#GO:0050431;protein binding#GO:0005515;growth factor binding#GO:0019838;cytokine binding#GO:0019955 inflammatory response#GO:0006954;immune response#GO:0006955;response to stress#GO:0006950;immune system process#GO:0002376;defense response#GO:0006952;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015707.3|UniProtKB=G3RI38 G3RI38 RBM23 PTHR48036:SF3 SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED RNA-BINDING PROTEIN 23-RELATED ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of cellular process#GO:0050794;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000044005.1|UniProtKB=A0A2I2YDQ6 A0A2I2YDQ6 TRIM4 PTHR24103:SF670 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM4 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to biotic stimulus#GO:0009607;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;immune system process#GO:0002376;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000001017.3|UniProtKB=A0A2I2YF16 A0A2I2YF16 SMAD9 PTHR13703:SF41 SMAD SMAD FAMILY MEMBER 9 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to transforming growth factor beta#GO:0071559;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular response to growth factor stimulus#GO:0071363;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 TGF-beta signaling pathway#P00052>RSmads#P01292;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819 GORGO|Ensembl=ENSGGOG00000014826.3|UniProtKB=A0A2I2YEC7 A0A2I2YEC7 CAMK2B PTHR24347:SF403 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT BETA kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 regulation of neuronal synaptic plasticity#GO:0048168;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of protein localization to membrane#GO:1905475;regulation of biological process#GO:0050789 neuron projection#GO:0043005;postsynapse#GO:0098794;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 non-receptor serine/threonine protein kinase#PC00167 Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Gonadotropin-releasing hormone receptor pathway#P06664>Ca/CaMK II#P06735 GORGO|Ensembl=ENSGGOG00000043843.1|UniProtKB=A0A2I2ZYG4 A0A2I2ZYG4 PTHR22916:SF73 GLYCOSYLTRANSFERASE QUEUOSINE-TRNA GALACTOSYLTRANSFERASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on RNA#GO:0140098;galactosyltransferase activity#GO:0008378;catalytic activity, acting on a tRNA#GO:0140101 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000039068.1|UniProtKB=A0A2I2YAL5 A0A2I2YAL5 PTHR33895:SF5 HUMANIN-LIKE 4 HUMANIN-LIKE 4-RELATED molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;signaling receptor regulator activity#GO:0030545 biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 GORGO|Ensembl=ENSGGOG00000016868.3|UniProtKB=G3RL24 G3RL24 KRT35 PTHR23239:SF193 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA5 structural molecule activity#GO:0005198 organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000002672.3|UniProtKB=G3QJN5 G3QJN5 ASB6 PTHR24132:SF24 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009077.3|UniProtKB=A0A2I2YUV1 A0A2I2YUV1 SH3BP5L PTHR19423:SF8 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5-LIKE guanyl-nucleotide exchange factor activity#GO:0005085;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000197.3|UniProtKB=G3QD84 G3QD84 AGT PTHR11461:SF13 SERINE PROTEASE INHIBITOR, SERPIN ANGIOTENSINOGEN peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>AngII#P05935 GORGO|Ensembl=ENSGGOG00000012069.3|UniProtKB=G3R8R6 G3R8R6 RRP1B PTHR13026:SF2 NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52 RIBOSOMAL RNA PROCESSING PROTEIN 1 HOMOLOG B transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000023727.2|UniProtKB=A0A2I2ZQL1 A0A2I2ZQL1 LOC101135835 PTHR26453:SF28 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2M5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040929.1|UniProtKB=A0A2I2YEB4 A0A2I2YEB4 PTHR11721:SF14 60S RIBOSOMAL PROTEIN L27A LARGE RIBOSOMAL SUBUNIT PROTEIN UL15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000026717.2|UniProtKB=G3SJJ3 G3SJJ3 TEX38 PTHR37362:SF1 TESTIS-EXPRESSED PROTEIN 38 TESTIS-EXPRESSED PROTEIN 38 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000015163.3|UniProtKB=G3RGP2 G3RGP2 SLC24A5 PTHR10846:SF61 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 5 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000025612.2|UniProtKB=G3S462 G3S462 NOL8 PTHR15241:SF396 TRANSFORMER-2-RELATED TRANSFORMER-2 PROTEIN HOMOLOG ALPHA RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000012111.3|UniProtKB=G3R8U5 G3R8U5 OTUB1 PTHR12931:SF19 UBIQUITIN THIOLESTERASE PROTEIN OTUB UBIQUITIN THIOESTERASE OTUB1 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin binding#GO:0043130;protein binding#GO:0005515;hydrolase activity#GO:0016787;binding#GO:0005488;deubiquitinase activity#GO:0101005 response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010042.3|UniProtKB=G3R3H3 G3R3H3 HPCA PTHR23055:SF57 CALCIUM BINDING PROTEINS NEURON-SPECIFIC CALCIUM-BINDING PROTEIN HIPPOCALCIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000000288.3|UniProtKB=G3SG36 G3SG36 ANKHD1 PTHR23206:SF5 MASK PROTEIN ANKYRIN REPEAT AND KH DOMAIN-CONTAINING PROTEIN 1 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008973.3|UniProtKB=A0A2I2ZA56 A0A2I2ZA56 SLC11A2 PTHR11706:SF40 SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2 cation binding#GO:0043169;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion binding#GO:0046872;iron ion transmembrane transporter activity#GO:0005381;transition metal ion binding#GO:0046914;ion binding#GO:0043167;transition metal ion transmembrane transporter activity#GO:0046915;binding#GO:0005488;small molecule binding#GO:0036094;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular iron ion homeostasis#GO:0006879;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;iron ion transport#GO:0006826;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;iron ion transmembrane transport#GO:0034755;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012594.4|UniProtKB=A0A2I2YDP0 A0A2I2YDP0 SLAIN2 PTHR22406:SF4 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM SLAIN MOTIF-CONTAINING PROTEIN 2 regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule polymerization#GO:0046785;positive regulation of cellular process#GO:0048522;microtubule polymerization or depolymerization#GO:0031109;biological regulation#GO:0065007;positive regulation of protein polymerization#GO:0032273;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;regulation of supramolecular fiber organization#GO:1902903;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular component organization#GO:0051130;regulation of microtubule polymerization#GO:0031113;positive regulation of organelle organization#GO:0010638;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;regulation of organelle organization#GO:0033043;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;cytoplasmic microtubule organization#GO:0031122 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;microtubule end#GO:1990752;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;microtubule plus-end#GO:0035371;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000004626.3|UniProtKB=G3QPN7 G3QPN7 TJP3 PTHR13865:SF11 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN ZO-3 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;cell-cell adhesion#GO:0098609;macromolecule localization#GO:0033036;biological regulation#GO:0065007;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;epithelium development#GO:0060429;cell-cell junction organization#GO:0045216;endothelial cell differentiation#GO:0045446;developmental process#GO:0032502;multicellular organismal-level homeostasis#GO:0048871;system process#GO:0003008;intracellular protein localization#GO:0008104;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell development#GO:0048468;homeostatic process#GO:0042592;cell junction organization#GO:0034330;cell differentiation#GO:0030154;cell adhesion#GO:0007155;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;protein localization to cell junction#GO:1902414;regulation of biological quality#GO:0065008;tissue homeostasis#GO:0001894;anatomical structure development#GO:0048856;localization#GO:0051179 apical junction complex#GO:0043296;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000042085.1|UniProtKB=A0A2I2ZJQ4 A0A2I2ZJQ4 PTHR35819:SF2 PICALM INTERACTING MITOTIC REGULATOR PIMREG PICALM INTERACTING MITOTIC REGULATOR GORGO|Ensembl=ENSGGOG00000039479.1|UniProtKB=A0A2I2YE30 A0A2I2YE30 PTHR11830:SF28 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006636.3|UniProtKB=A0A2I2Z6J7 A0A2I2Z6J7 DNM1L PTHR11566:SF39 DYNAMIN DYNAMIN-1-LIKE PROTEIN microtubule binding#GO:0008017;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 organelle fission#GO:0048285;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitochondrion localization#GO:0051646;organelle localization#GO:0051640;peroxisome organization#GO:0007031;mitochondrial fission#GO:0000266;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;programmed cell death#GO:0012501;organelle organization#GO:0006996;apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule#GO:0005874;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000023343.2|UniProtKB=G3SE49 G3SE49 NLRP9 PTHR45690:SF13 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 9 regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;canonical inflammasome complex#GO:0061702;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000003620.3|UniProtKB=A0A2I2Z917 A0A2I2Z917 FAM169A PTHR22442:SF3 FAMILY NOT NAMED SOLUBLE LAMIN-ASSOCIATED PROTEIN OF 75 KDA GORGO|Ensembl=ENSGGOG00000003156.3|UniProtKB=G3QKW8 G3QKW8 DTX3 PTHR12622:SF35 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX3 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cell surface receptor signaling pathway#GO:0007166;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;ubiquitin-dependent protein catabolic process#GO:0006511;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;cell communication#GO:0007154;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009827.3|UniProtKB=G3S764 G3S764 BRCA1 PTHR13763:SF11 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;damaged DNA binding#GO:0003684;DNA binding#GO:0003677;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;nucleic acid binding#GO:0003676;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;DNA repair complex#GO:1990391;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794;transferase complex#GO:1990234;condensed chromosome#GO:0000793;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000016446.3|UniProtKB=G3RJZ0 G3RJZ0 FAM3C PTHR14592:SF10 UNCHARACTERIZED FAM3 PROTEIN FAM3C receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000004673.3|UniProtKB=G3QPS9 G3QPS9 USPL1 PTHR15294:SF3 RETINOVIN-RELATED SUMO-SPECIFIC ISOPEPTIDASE USPL1 protein binding#GO:0005515;binding#GO:0005488 post-translational protein modification#GO:0043687;cellular process#GO:0009987;organelle organization#GO:0006996;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleus organization#GO:0006997;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000010751.3|UniProtKB=G3R5B8 G3R5B8 PTHR24384:SF30 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 664 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000005626.3|UniProtKB=G3QYP2 G3QYP2 ECEL1 PTHR11733:SF195 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED ENDOTHELIN-CONVERTING ENZYME-LIKE 1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 GORGO|Ensembl=ENSGGOG00000011146.3|UniProtKB=G3RZZ5 G3RZZ5 NPFFR2 PTHR24241:SF132 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016864.3|UniProtKB=G3RL20 G3RL20 CFAP46 PTHR15977:SF15 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 46 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 46 GORGO|Ensembl=ENSGGOG00000005359.3|UniProtKB=A0A2I2Z1A0 A0A2I2Z1A0 PTHR11886:SF75 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN binding#GO:0005488;protein binding#GO:0005515 cilium assembly#GO:0060271;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970 dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000037052.1|UniProtKB=A0A2I2YFF7 A0A2I2YFF7 FOXL3 PTHR11829:SF211 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000022712.2|UniProtKB=G3RQT6 G3RQT6 ZNF836 PTHR24377:SF794 IP01015P-RELATED ZINC FINGER PROTEIN 836 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002215.3|UniProtKB=G3QIH1 G3QIH1 HOXA4 PTHR45771:SF2 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-A4 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;skeletal system morphogenesis#GO:0048705;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;positive regulation of RNA metabolic process#GO:0051254;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;anterior/posterior pattern specification#GO:0009952;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;skeletal system development#GO:0001501;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000022397.2|UniProtKB=G3S2I6 G3S2I6 PTHR20981:SF8 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008997.3|UniProtKB=G3RVT9 G3RVT9 CSNK2A1 PTHR24054:SF16 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459 GORGO|Ensembl=ENSGGOG00000005058.3|UniProtKB=G3QQT1 G3QQT1 ICMT PTHR12714:SF9 PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;O-methyltransferase activity#GO:0008171;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010104.3|UniProtKB=G3R3M9 G3R3M9 JUP PTHR45976:SF3 ARMADILLO SEGMENT POLARITY PROTEIN JUNCTION PLAKOGLOBIN protein phosphatase binding#GO:0019903;transcription coactivator activity#GO:0003713;cell adhesion molecule binding#GO:0050839;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488 cell adhesion#GO:0007155;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell-cell adhesion#GO:0098609;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219 adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;nucleus#GO:0005634;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796 Alzheimer disease-presenilin pathway#P00004>gammacatenin#P00153 GORGO|Ensembl=ENSGGOG00000039800.1|UniProtKB=A0A2I2YRI8 A0A2I2YRI8 GNB1L PTHR19854:SF1 TRANSDUCIN BETA-LIKE 3 GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016457.3|UniProtKB=G3RK02 G3RK02 BICD1 PTHR31233:SF3 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D HOMOLOG 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal adaptor activity#GO:0008093;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of endocytosis#GO:0045807;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of endocytosis#GO:0030100;microtubule anchoring#GO:0034453;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of transport#GO:0051049;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of receptor-mediated endocytosis#GO:0048259;regulation of microtubule-based process#GO:0032886;positive regulation of cellular component organization#GO:0051130;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000024956.2|UniProtKB=G3S1K9 G3S1K9 PTHR23266:SF114 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-15 antigen binding#GO:0003823;binding#GO:0005488 immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000003912.3|UniProtKB=G3S7V2 G3S7V2 CDC25A PTHR10828:SF46 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 M-PHASE INDUCER PHOSPHATASE 1 hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;regulation of reproductive process#GO:2000241;positive regulation of cellular process#GO:0048522;cell cycle G2/M phase transition#GO:0044839;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic cell cycle phase transition#GO:0044772 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway#P00059>Cdc25C#P04624 GORGO|Ensembl=ENSGGOG00000009899.3|UniProtKB=A0A2I2Y8X8 A0A2I2Y8X8 MYBPH PTHR13817:SF49 TITIN MYOSIN-BINDING PROTEIN H structural molecule activity#GO:0005198 muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cell development#GO:0048468;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;contractile muscle fiber#GO:0043292;A band#GO:0031672;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular organelle#GO:0043229;M band#GO:0031430 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000028226.2|UniProtKB=A0A2I2ZP92 A0A2I2ZP92 CPS1 PTHR11405:SF58 CARBAMOYLTRANSFERASE FAMILY MEMBER CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 GORGO|Ensembl=ENSGGOG00000013647.3|UniProtKB=G3RCT1 G3RCT1 KLB PTHR10353:SF68 GLYCOSYL HYDROLASE BETA-KLOTHO hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosidase#PC00110;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000028027.2|UniProtKB=G3RSY2 G3RSY2 SPCS1 PTHR13202:SF0 MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 1 metabolic process#GO:0008152;protein targeting to ER#GO:0045047;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of protein localization#GO:0045184;biosynthetic process#GO:0009058;establishment of protein localization to endoplasmic reticulum#GO:0072599;gene expression#GO:0010467;protein maturation#GO:0051604;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;protein targeting#GO:0006605 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 protein modifying enzyme#PC00260;protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 GORGO|Ensembl=ENSGGOG00000022398.2|UniProtKB=G3S8C9 G3S8C9 INHBC PTHR11848:SF130 TGF-BETA FAMILY INHIBIN BETA C CHAIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000010259.3|UniProtKB=G3RMA5 G3RMA5 PTPN2 PTHR46047:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 2 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000007131.3|UniProtKB=G3QW27 G3QW27 TMEM115 PTHR13377:SF3 PLACENTAL PROTEIN 6 TRANSMEMBRANE PROTEIN 115 cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 Golgi stack#GO:0005795;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015225.3|UniProtKB=A0A2I2Y742 A0A2I2Y742 LOC101123935 PTHR15924:SF10 CLE RNA TRANSCRIPTION, TRANSLATION AND TRANSPORT FACTOR PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000015386.3|UniProtKB=G3RH91 G3RH91 BARX2 PTHR24330:SF7 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN BARH-LIKE 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000000676.3|UniProtKB=G3QEH1 G3QEH1 CGRRF1 PTHR15379:SF2 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 negative regulation of cellular process#GO:0048523;negative regulation of cell growth#GO:0030308;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell growth#GO:0001558;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;negative regulation of biological process#GO:0048519 GORGO|Gene=1C02_GORGO|UniProtKB=P30385 P30385 PTHR16675:SF294 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, C ALPHA CHAIN antigen binding#GO:0003823;peptide binding#GO:0042277;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000014490.3|UniProtKB=G3REZ5 G3REZ5 RBM5 PTHR13948:SF21 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 5 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000022735.2|UniProtKB=G3RU77 G3RU77 GPD2 PTHR11985:SF29 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000026889.2|UniProtKB=G3SHT9 G3SHT9 RWDD1 PTHR12292:SF9 RWD DOMAIN-CONTAINING PROTEIN RWD DOMAIN-CONTAINING PROTEIN 1 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;steroid hormone receptor signaling pathway#GO:0043401;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to steroid hormone#GO:0048545;cellular response to chemical stimulus#GO:0070887;intracellular signal transduction#GO:0035556;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;response to hormone#GO:0009725;biological regulation#GO:0065007;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;nuclear receptor-mediated signaling pathway#GO:0141193;cellular response to steroid hormone stimulus#GO:0071383 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000010987.3|UniProtKB=G3R5X8 G3R5X8 SNX17 PTHR12431:SF16 SORTING NEXIN 17 AND 27 SORTING NEXIN-17 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907;metabolic process#GO:0008152;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005152.3|UniProtKB=A0A2I2ZM97 A0A2I2ZM97 LOC101152722 PTHR16719:SF0 CYTOCHROME C OXIDASE COPPER CHAPERONE CYTOCHROME C OXIDASE COPPER CHAPERONE molecular carrier activity#GO:0140104 mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005 organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000016126.3|UniProtKB=G3RJ57 G3RJ57 TGM6 PTHR11590:SF50 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 6 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;epithelium development#GO:0060429;cell differentiation#GO:0030154;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;skin development#GO:0043588;epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;animal organ development#GO:0048513 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000002889.3|UniProtKB=G3QK74 G3QK74 SLC39A8 PTHR12191:SF2 SOLUTE CARRIER FAMILY 39 METAL CATION SYMPORTER ZIP8 monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012604.3|UniProtKB=G3RA44 G3RA44 PRKCG PTHR24356:SF162 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C GAMMA TYPE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Apoptosis signaling pathway#P00006>PKCs#P00318;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Angiogenesis#P00005>PKC#P00219;VEGF signaling pathway#P00056>PKC#P01425;Endothelin signaling pathway#P00019>PKC#P00568;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;FGF signaling pathway#P00021>PKC#P00648;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 GORGO|Ensembl=ENSGGOG00000000684.3|UniProtKB=G3QEH9 G3QEH9 PRM2 PTHR21341:SF2 PROTAMINE-2 PROTAMINE-2 cellular component organization#GO:0016043;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;organelle organization#GO:0006996;cellular process#GO:0009987;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;cellular developmental process#GO:0048869 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015765.3|UniProtKB=G3RI83 G3RI83 HOXC13 PTHR45804:SF5 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-C13 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000007987.3|UniProtKB=G3QY82 G3QY82 PCGF2 PTHR10825:SF31 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 2 binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000005556.3|UniProtKB=G3RTN4 G3RTN4 EIF2AK2 PTHR11042:SF163 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED INTERFERON-INDUCED, DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>PKR#P00293 GORGO|Ensembl=ENSGGOG00000004945.3|UniProtKB=G3QQI0 G3QQI0 VAMP8 PTHR45701:SF7 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 8 syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090 localization#GO:0051179;secretion#GO:0046903;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of body fluid levels#GO:0050878;vesicle fusion#GO:0006906;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532 GORGO|Ensembl=ENSGGOG00000038154.1|UniProtKB=A0A2I2ZXD4 A0A2I2ZXD4 SMIM14 PTHR31019:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 14 SMALL INTEGRAL MEMBRANE PROTEIN 14 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000044092.1|UniProtKB=A0A2I2YGC5 A0A2I2YGC5 PTHR23310:SF110 ACYL-COA-BINDING PROTEIN, ACBP ACB DOMAIN-CONTAINING PROTEIN binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;lipid binding#GO:0008289;heterocyclic compound binding#GO:1901363 cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000005175.3|UniProtKB=G3QR34 G3QR34 LOC109028370 PTHR26453:SF198 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011644.3|UniProtKB=G3R7L5 G3R7L5 PTHR11461:SF166 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B8 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000004127.3|UniProtKB=G3QND9 G3QND9 ARID5B PTHR13964:SF37 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5B DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000009512.3|UniProtKB=G3R254 G3R254 PRR27 PTHR39415:SF1 PROLINE-RICH PROTEIN 27 PROLINE-RICH PROTEIN 27 GORGO|Ensembl=ENSGGOG00000003163.3|UniProtKB=A0A2I2Z3V3 A0A2I2Z3V3 FAM53A PTHR28567:SF2 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53A nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011906.3|UniProtKB=G3R8B6 G3R8B6 KPNA5 PTHR23316:SF10 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-6 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000009858.4|UniProtKB=G3R325 G3R325 CATSPERB PTHR14705:SF0 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT BETA CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT BETA cellular process#GO:0009987;male gamete generation#GO:0048232;developmental maturation#GO:0021700;sperm capacitation#GO:0048240;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;cell maturation#GO:0048469;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;gamete generation#GO:0007276;cell differentiation#GO:0030154;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609 CatSper complex#GO:0036128;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;cation channel complex#GO:0034703;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000041885.1|UniProtKB=A0A2I2YBF1 A0A2I2YBF1 PTHR19430:SF1 PROTEIN BEX1-RELATED PROTEIN BEX3 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000042678.1|UniProtKB=A0A2I2ZEE7 A0A2I2ZEE7 C4orf50 PTHR36866:SF1 CHROMOSOME 4 OPEN READING FRAME 50 GENE 1043-RELATED GORGO|Ensembl=ENSGGOG00000003245.3|UniProtKB=G3RWJ2 G3RWJ2 KLF5 PTHR23235:SF82 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000028321.2|UniProtKB=G3RT73 G3RT73 ANKRD65 PTHR24166:SF52 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 65 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001662.3|UniProtKB=G3QH20 G3QH20 SPTLC1 PTHR13693:SF2 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 ceramide metabolic process#GO:0006672;sphingoid biosynthetic process#GO:0046520;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000004620.3|UniProtKB=G3QPM9 G3QPM9 PTHR31770:SF1 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-2 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;chemokine#PC00074 GORGO|Ensembl=ENSGGOG00000014777.3|UniProtKB=G3S1N5 G3S1N5 NUDT9 PTHR13030:SF8 NUDIX HYDROLASE ADP-RIBOSE PYROPHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000023706.2|UniProtKB=G3RMU0 G3RMU0 CTDSP2 PTHR12210:SF187 DULLARD PROTEIN PHOSPHATASE CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 2 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000011080.3|UniProtKB=G3R664 G3R664 GCH1 PTHR11109:SF11 GTP CYCLOHYDROLASE I GTP CYCLOHYDROLASE 1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 Tetrahydrofolate biosynthesis#P02742>GTP cyclohydrolase#P02951 GORGO|Ensembl=ENSGGOG00000034874.2|UniProtKB=G3SKR5 G3SKR5 NKAIN3 PTHR13084:SF2 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 3 regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000017108.3|UniProtKB=A0A2I2Z8X7 A0A2I2Z8X7 SIM1 PTHR23043:SF22 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA SINGLE-MINDED HOMOLOG 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000012030.3|UniProtKB=A0A2I2YFU8 A0A2I2YFU8 ZFP64 PTHR24403:SF43 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 64 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006615.3|UniProtKB=G3QUR4 G3QUR4 ST6GAL1 PTHR46059:SF2 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000003133.3|UniProtKB=A0A2I2YVQ6 A0A2I2YVQ6 PTHR13349:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000016504.3|UniProtKB=G3RK42 G3RK42 FAM118B PTHR28623:SF1 PROTEIN FAM118B PROTEIN FAM118B hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376 GORGO|Ensembl=ENSGGOG00000014169.3|UniProtKB=G3S2Q0 G3S2Q0 PTHR16247:SF0 RIKEN CDNA 9430015G10 GENE RIKEN CDNA 9430015G10 GENE GORGO|Ensembl=ENSGGOG00000009596.3|UniProtKB=A0A2I2Y561 A0A2I2Y561 COQ8A PTHR43851:SF1 FAMILY NOT NAMED ATYPICAL KINASE COQ8A, MITOCHONDRIAL small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 GORGO|Ensembl=ENSGGOG00000014089.3|UniProtKB=G3RDY2 G3RDY2 LOC101153957 PTHR23226:SF151 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5C DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015477.3|UniProtKB=A0A2I2ZNZ1 A0A2I2ZNZ1 SOS2 PTHR23113:SF150 GUANINE NUCLEOTIDE EXCHANGE FACTOR SON OF SEVENLESS HOMOLOG 2 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 T cell activation#P00053>SOS#P01307;FGF signaling pathway#P00021>SOS#P00641;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883;PI3 kinase pathway#P00048>SOS#P01185;Interleukin signaling pathway#P00036>SOS#P00981;Ras Pathway#P04393>SOS#P04552;Gonadotropin-releasing hormone receptor pathway#P06664>Sos#P06849;EGF receptor signaling pathway#P00018>SOS#P00558;PDGF signaling pathway#P00047>SOS#P01159;Angiogenesis#P00005>SOS-1#P00193;B cell activation#P00010>SOS#P00379;Integrin signalling pathway#P00034>SOS#P00920 GORGO|Ensembl=ENSGGOG00000043372.1|UniProtKB=G3QCU9 G3QCU9 ZNF146 PTHR24404:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 835 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010594.3|UniProtKB=A0A2I2Z380 A0A2I2Z380 TPCN2 PTHR46768:SF1 TWO PORE CALCIUM CHANNEL PROTEIN 2 TWO PORE CHANNEL PROTEIN 2 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 cell communication#GO:0007154;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;biological process involved in symbiotic interaction#GO:0044403;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological process involved in interaction with host#GO:0051701;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ion channel#PC00133 CCKR signaling map#P06959>TPC1/2#P07209 GORGO|Ensembl=ENSGGOG00000027260.2|UniProtKB=G3S443 G3S443 RBMXL3 PTHR48034:SF3 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA-BINDING MOTIF PROTEIN, X-LINKED-LIKE-2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006586.3|UniProtKB=G3QUP6 G3QUP6 PLD2 PTHR18896:SF121 PHOSPHOLIPASE D PHOSPHOLIPASE D2 hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of transport#GO:0051049;regulation of localization#GO:0032879;organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987;biological regulation#GO:0065007 cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 phospholipase#PC00186;lipase#PC00143 Angiogenesis#P00005>PLD#P00204;Parkinson disease#P00049>PLD2#P01207;Ras Pathway#P04393>PLD#P04574 GORGO|Ensembl=ENSGGOG00000014243.3|UniProtKB=G3REB3 G3REB3 GLMP PTHR31981:SF1 GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000026809.2|UniProtKB=G3SJL3 G3SJL3 LLPH PTHR34253:SF3 PROTEIN LLP HOMOLOG PROTEIN LLP HOMOLOG cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell growth#GO:0016049;developmental growth#GO:0048589;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;system development#GO:0048731;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;developmental cell growth#GO:0048588;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000039460.1|UniProtKB=A0A2I2ZB59 A0A2I2ZB59 C4A PTHR11412:SF86 MACROGLOBULIN / COMPLEMENT COMPLEMENT C4-A-RELATED receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000013668.3|UniProtKB=G3RCV1 G3RCV1 PRMT9 PTHR11006:SF60 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 9 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000027771.2|UniProtKB=G3S2K5 G3S2K5 PTHR45997:SF4 DNA LIGASE 4 DNA LIGASE 4 ligase activity#GO:0016874;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ATP binding#GO:0005524;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;system development#GO:0048731;anatomical structure development#GO:0048856;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;somatic cell DNA recombination#GO:0016444;multicellular organismal process#GO:0032501;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;developmental process#GO:0032502;DNA damage response#GO:0006974;DNA repair#GO:0006281;response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;V(D)J recombination#GO:0033151;immune system development#GO:0002520;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;cellular response to stress#GO:0033554;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;nucleotide-excision repair#GO:0006289;gene expression#GO:0010467;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;multicellular organism development#GO:0007275;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nonhomologous end joining complex#GO:0070419;intracellular membrane-bounded organelle#GO:0043231;DNA repair complex#GO:1990391;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000002962.3|UniProtKB=G3QKD9 G3QKD9 LOC101151246 PTHR24300:SF356 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2E1 heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;binding#GO:0005488;tetrapyrrole binding#GO:0046906 lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;cellular response to xenobiotic stimulus#GO:0071466;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;olefinic compound metabolic process#GO:0120254;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;oxoacid metabolic process#GO:0043436;xenobiotic metabolic process#GO:0006805;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;arachidonate metabolic process#GO:0019369;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000007525.3|UniProtKB=G3QX34 G3QX34 BPGM PTHR11931:SF11 PHOSPHOGLYCERATE MUTASE BISPHOSPHOGLYCERATE MUTASE phosphoglycerate mutase activity#GO:0004619;isomerase activity#GO:0016853;intramolecular phosphotransferase activity#GO:0016868;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 isomerase#PC00135;mutase#PC00160 Glycolysis#P00024>Phosphoglyceromutase#P00680 GORGO|Ensembl=ENSGGOG00000005408.3|UniProtKB=G3RMP0 G3RMP0 LIX1L PTHR31139:SF3 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG LIX1-LIKE PROTEIN cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000026177.2|UniProtKB=G3S9N5 G3S9N5 AHNAK PTHR23348:SF41 PERIAXIN/AHNAK NEUROBLAST DIFFERENTIATION-ASSOCIATED PROTEIN AHNAK regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000013585.3|UniProtKB=G3RCL5 G3RCL5 LOC101148034 PTHR37358:SF1 MUCIN-20 MUCIN-20 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000002196.3|UniProtKB=G3SGB9 G3SGB9 ZNF747 PTHR24393:SF65 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 768 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010655.3|UniProtKB=G3R521 G3R521 LRTM2 PTHR24369:SF221 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000025961.2|UniProtKB=G3S232 G3S232 LCN12 PTHR11430:SF12 LIPOCALIN EPIDIDYMAL-SPECIFIC LIPOCALIN-12 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000011729.3|UniProtKB=A0A2I2YQD4 A0A2I2YQD4 ANK1 PTHR24161:SF97 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN 2 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023909.2|UniProtKB=G3RXS8 G3RXS8 ZSCAN16 PTHR23226:SF52 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 16 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012999.3|UniProtKB=G3RB35 G3RB35 EFTUD2 PTHR42908:SF6 TRANSLATION ELONGATION FACTOR-RELATED 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;snRNA binding#GO:0017069;hydrolase activity#GO:0016787;RNA binding#GO:0003723;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;binding#GO:0005488;GTPase activity#GO:0003924 protein biosynthetic process#GO:0160307;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein metabolic process#GO:0019538;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;translation#GO:0006412;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;translational elongation#GO:0006414;RNA splicing#GO:0008380 ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytoplasm#GO:0005737 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000043674.1|UniProtKB=A0A2I2YDQ5 A0A2I2YDQ5 CUTC PTHR12598:SF0 COPPER HOMEOSTASIS PROTEIN CUTC COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000009699.3|UniProtKB=G3R2M1 G3R2M1 ARRB1 PTHR11792:SF22 ARRESTIN BETA-ARRESTIN-1 G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 negative regulation of cell communication#GO:0010648;positive regulation of signaling#GO:0023056;nervous system process#GO:0050877;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;endocytosis#GO:0006897;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;import into cell#GO:0098657;regulation of MAPK cascade#GO:0043408;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;vesicle-mediated transport#GO:0016192;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;receptor internalization#GO:0031623;localization#GO:0051179;sensory perception#GO:0007600;regulation of Notch signaling pathway#GO:0008593;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of signal transduction#GO:0009967;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;system process#GO:0003008;receptor-mediated endocytosis#GO:0006898;positive regulation of MAPK cascade#GO:0043410;establishment of localization#GO:0051234;negative regulation of Notch signaling pathway#GO:0045746;positive regulation of intracellular signal transduction#GO:1902533;regulation of G protein-coupled receptor signaling pathway#GO:0008277;transport#GO:0006810;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944;cytosol#GO:0005829;intracellular vesicle#GO:0097708;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723;Wnt signaling pathway#P00057>beta-arrestin#P01456;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR1#P05925 GORGO|Ensembl=ENSGGOG00000023253.2|UniProtKB=G3RX18 G3RX18 PTHR24416:SF509 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TYRO3 transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672 regulation of cellular process#GO:0050794;cell motility#GO:0048870;hemostasis#GO:0007599;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;system development#GO:0048731;cell activation#GO:0001775;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;cell migration#GO:0016477;homotypic cell-cell adhesion#GO:0034109;biological regulation#GO:0065007;response to wounding#GO:0009611;establishment of localization#GO:0051234;platelet activation#GO:0030168;blood coagulation#GO:0007596;phagocytosis#GO:0006909;transport#GO:0006810;developmental process#GO:0032502;regulation of body fluid levels#GO:0050878;endocytosis#GO:0006897;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;wound healing#GO:0042060;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;nervous system development#GO:0007399;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;coagulation#GO:0050817;signal transduction#GO:0007165;import into cell#GO:0098657;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;platelet aggregation#GO:0070527 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000023013.2|UniProtKB=G3RRV4 G3RRV4 PACSIN1 PTHR23065:SF16 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 1 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 nervous system development#GO:0007399;endomembrane system organization#GO:0010256;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of endocytosis#GO:0030100;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;plasma membrane organization#GO:0007009;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;positive regulation of neuron projection development#GO:0010976;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;membrane organization#GO:0061024;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;system development#GO:0048731;positive regulation of cell projection organization#GO:0031346 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Huntington disease#P00029>PACSIN-1#P00802 GORGO|Ensembl=ENSGGOG00000004096.3|UniProtKB=G3QNA8 G3QNA8 YIPF7 PTHR21236:SF5 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF7 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000006825.3|UniProtKB=G3QVC7 G3QVC7 ZMYM3 PTHR45736:SF3 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 3 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000024150.2|UniProtKB=A0A2I2ZS33 A0A2I2ZS33 SPINK2 PTHR47608:SF1 SERINE PROTEASE INHIBITOR KAZAL-TYPE 2, SPINK2 SERINE PROTEASE INHIBITOR KAZAL-TYPE 2 male gamete generation#GO:0048232;cellular process#GO:0009987;cellular developmental process#GO:0048869;developmental process#GO:0032502;spermatogenesis#GO:0007283;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;spermatid development#GO:0007286;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515 intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000015103.3|UniProtKB=G3RGJ4 G3RGJ4 KCP PTHR46698:SF2 CROSSVEINLESS 2 KIELIN_CHORDIN-LIKE PROTEIN regulation of response to stimulus#GO:0048583;positive regulation of BMP signaling pathway#GO:0030513;regulation of BMP signaling pathway#GO:0030510;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000014295.3|UniProtKB=G3REF4 G3REF4 PTAFR PTHR24233:SF6 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PLATELET-ACTIVATING FACTOR RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000008796.3|UniProtKB=G3R0C0 G3R0C0 GRIN2A PTHR18966:SF407 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2A voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;voltage-gated channel activity#GO:0022832;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;nervous system process#GO:0050877;regulation of signaling#GO:0023051;positive regulation of synaptic transmission#GO:0050806;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission, postsynaptic#GO:0099565;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of postsynaptic membrane potential#GO:0060078;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;system process#GO:0003008;regulation of synaptic plasticity#GO:0048167;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522 plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;transporter complex#GO:1990351;cell junction#GO:0030054 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NR2C#P01006;Ionotropic glutamate receptor pathway#P00037>NR2B#P01007;Ionotropic glutamate receptor pathway#P00037>NR2A#P01008;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Huntington disease#P00029>NMDA receptor#P00778;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039 GORGO|Ensembl=ENSGGOG00000000130.3|UniProtKB=G3QD26 G3QD26 ATP4A PTHR43294:SF10 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1 ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399 sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;import across plasma membrane#GO:0098739;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;potassium ion homeostasis#GO:0055075;localization#GO:0051179;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023820.2|UniProtKB=A0A2I2ZI43 A0A2I2ZI43 LOC101136563 PTHR47901:SF3 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 CASPASE-1 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;gene expression#GO:0010467;protein maturation#GO:0051604;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;positive regulation of apoptotic process#GO:0043065 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;canonical inflammasome complex#GO:0061702;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000014820.3|UniProtKB=G3RFT3 G3RFT3 PRKAG2 PTHR13780:SF122 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-2 nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;cation binding#GO:0043169;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265 response to nutrient levels#GO:0031667;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cellular response to glucose starvation#GO:0042149;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cellular response to starvation#GO:0009267;regulation of carbohydrate metabolic process#GO:0006109;cellular response to nutrient levels#GO:0031669;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;response to starvation#GO:0042594;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of carbohydrate biosynthetic process#GO:0043255;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 GORGO|Ensembl=ENSGGOG00000023575.2|UniProtKB=A0A2I2ZDJ2 A0A2I2ZDJ2 LOC101128376 PTHR11431:SF94 FERRITIN FERRITIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000003256.3|UniProtKB=A0A2I2ZDS8 A0A2I2ZDS8 CDC34 PTHR24067:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 R1 aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000013156.3|UniProtKB=G3RLY6 G3RLY6 LOC101140763 PTHR12011:SF328 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E2 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000027782.2|UniProtKB=G3SG50 G3SG50 RINL PTHR23101:SF72 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR-LIKE PROTEIN molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000002631.3|UniProtKB=G3QJJ8 G3QJJ8 ABL2 PTHR24418:SF87 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of biological process#GO:0050789;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 GORGO|Ensembl=ENSGGOG00000027387.2|UniProtKB=G3SIA8 G3SIA8 AVPR2 PTHR24241:SF20 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V2 RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 system process#GO:0003008;regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;regulation of biological quality#GO:0065008;cell communication#GO:0007154;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000043819.1|UniProtKB=A0A2I2YIZ4 A0A2I2YIZ4 CREB5 PTHR19304:SF8 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 5 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 GORGO|Ensembl=ENSGGOG00000016055.3|UniProtKB=A0A2I2ZAP2 A0A2I2ZAP2 PTHR46337:SF1 RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;mitochondrial ribosome assembly#GO:0061668;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial fusion#GO:0008053;ribonucleoprotein complex biogenesis#GO:0022613;mitochondrion organization#GO:0007005;organelle fusion#GO:0048284;cellular component assembly#GO:0022607 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 GORGO|Ensembl=ENSGGOG00000003996.3|UniProtKB=G3QN19 G3QN19 PTHR45925:SF3 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 516 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000003360.3|UniProtKB=G3QLF1 G3QLF1 CCR10 PTHR10489:SF735 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 10 cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;locomotion#GO:0040011;signaling#GO:0023052;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;chemotaxis#GO:0006935;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000009629.3|UniProtKB=G3R2G1 G3R2G1 SLC12A7 PTHR11827:SF47 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 7 symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transport#GO:0006813;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000036684.1|UniProtKB=A0A2I2ZV29 A0A2I2ZV29 PTHR23232:SF112 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 726 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009046.3|UniProtKB=G3R0Z4 G3R0Z4 PPM1D PTHR47992:SF253 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1D catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;mitogen-activated protein kinase binding#GO:0051019;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;hydrolase activity#GO:0016787;protein binding#GO:0005515;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;chromatin organization#GO:0006325;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 protein modifying enzyme#PC00260;protein phosphatase#PC00195 p53 pathway feedback loops 2#P04398>WIP-1#G04708;p53 pathway#P00059>WIP-1#G04693;p53 pathway feedback loops 2#P04398>WIP-1#P04650 GORGO|Ensembl=ENSGGOG00000025165.2|UniProtKB=G3SFJ3 G3SFJ3 TMEM69 PTHR15887:SF4 TRANSMEMBRANE PROTEIN 69 TRANSMEMBRANE PROTEIN 69 GORGO|Ensembl=ENSGGOG00000013574.3|UniProtKB=A0A2I2Z6P3 A0A2I2Z6P3 PDHA1 PTHR11516:SF52 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA, SOMATIC FORM, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521 membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;dehydrogenase#PC00092 Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133;TCA cycle#P00051>Pyruvate Dehydrogenase#P01266 GORGO|Ensembl=ENSGGOG00000001295.3|UniProtKB=G3QG28 G3QG28 FAM221A PTHR31214:SF2 PROTEIN FAM221A-RELATED PROTEIN FAM221A GORGO|Ensembl=ENSGGOG00000003790.3|UniProtKB=G3QMI0 G3QMI0 ESX1 PTHR24329:SF545 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ESX1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000026727.3|UniProtKB=G3SHY3 G3SHY3 TERF1 PTHR46734:SF3 TELOMERIC REPEAT-BINDING FACTOR 1 TERF1 TELOMERIC REPEAT-BINDING FACTOR 1 double-stranded DNA binding#GO:0003690;RNA-directed DNA polymerase activity#GO:0003964;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;catalytic activity, acting on DNA#GO:0140097;telomerase activity#GO:0003720;DNA polymerase activity#GO:0034061;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 negative regulation of chromosome organization#GO:2001251;telomere organization#GO:0032200;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;RNA-templated DNA biosynthetic process#GO:0006278;telomere maintenance#GO:0000723;regulation of telomere maintenance#GO:0032204;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of DNA metabolic process#GO:0051053;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid biosynthetic process#GO:0141187;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;organelle organization#GO:0006996;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;nuclear telomere cap complex#GO:0000783;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000001623.3|UniProtKB=G3S362 G3S362 PARP14 PTHR14453:SF89 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;negative regulation of response to cytokine stimulus#GO:0060761;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of response to cytokine stimulus#GO:0060759;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;negative regulation of innate immune response#GO:0045824;negative regulation of signal transduction#GO:0009968;negative regulation of cytokine-mediated signaling pathway#GO:0001960;regulation of cytokine-mediated signaling pathway#GO:0001959;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001090.3|UniProtKB=G3QFK0 G3QFK0 PTHR16263:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 38 TETRATRICOPEPTIDE REPEAT PROTEIN 38 GORGO|Ensembl=ENSGGOG00000000553.3|UniProtKB=G3QE57 G3QE57 REG4 PTHR22802:SF345 C-TYPE LECTIN SUPERFAMILY MEMBER RERATING FAMILY MEMBER 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000007445.3|UniProtKB=G3QWW1 G3QWW1 AP2M1 PTHR10529:SF373 AP COMPLEX SUBUNIT MU AP-2 COMPLEX SUBUNIT MU cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;postsynaptic neurotransmitter receptor internalization#GO:0098884;regulation of biological quality#GO:0065008;post-Golgi vesicle-mediated transport#GO:0006892;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641;localization#GO:0051179;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;receptor internalization#GO:0031623;receptor-mediated endocytosis#GO:0006898;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072 organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated endocytic vesicle#GO:0045334;cell junction#GO:0030054;clathrin vesicle coat#GO:0030125;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;vesicle coat#GO:0030120;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;presynapse#GO:0098793;secretory vesicle#GO:0099503;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;endocytic vesicle#GO:0030139;coated membrane#GO:0048475;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;clathrin coat#GO:0030118;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905 membrane traffic protein#PC00150 CCKR signaling map#P06959>AP2M1#P07067 GORGO|Ensembl=ENSGGOG00000012793.3|UniProtKB=G3RAK3 G3RAK3 KIFBP PTHR46321:SF1 KIF1-BINDING PROTEIN KIF-BINDING PROTEIN animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;neuron projection organization#GO:0106027;cell projection organization#GO:0030030;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell morphogenesis#GO:0000902;cell development#GO:0048468;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;central nervous system neuron differentiation#GO:0021953;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;axon development#GO:0061564;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036 GORGO|Ensembl=ENSGGOG00000011837.3|UniProtKB=G3R845 G3R845 MS4A15 PTHR23320:SF51 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 15 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040409.1|UniProtKB=A0A2I2Z9H0 A0A2I2Z9H0 PTHR23105:SF118 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 2 RNA binding#GO:0003723;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488 rRNA processing#GO:0006364;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010178.3|UniProtKB=G3R3U7 G3R3U7 MAVS PTHR21446:SF6 DUF3504 DOMAIN-CONTAINING PROTEIN MITOCHONDRIAL ANTIVIRAL-SIGNALING PROTEIN GORGO|Ensembl=ENSGGOG00000037244.1|UniProtKB=A0A2I2Z7I5 A0A2I2Z7I5 GFRA4 PTHR10269:SF2 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-4 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040285.1|UniProtKB=A0A2I2ZW62 A0A2I2ZW62 GPR162 PTHR16518:SF6 G-PROTEIN COUPLED RECEPTOR 153, 162 G PROTEIN-COUPLED RECEPTOR 162-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000017045.3|UniProtKB=A0A2I2ZCE0 A0A2I2ZCE0 FRMD5 PTHR23280:SF5 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN 5 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell adhesion#GO:0045785 anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000009657.3|UniProtKB=G3S8L7 G3S8L7 SH2D4A PTHR14388:SF5 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 4A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000005053.3|UniProtKB=G3QQT2 G3QQT2 EGFLAM PTHR15036:SF88 PIKACHURIN-LIKE PROTEIN PIKACHURIN response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;developmental process#GO:0032502 cell junction#GO:0030054;extracellular region#GO:0005576;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;cell periphery#GO:0071944;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;membrane#GO:0016020 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000034960.2|UniProtKB=G3SKS5 G3SKS5 CDHR3 PTHR24028:SF262 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 3 cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000007829.3|UniProtKB=G3RVS1 G3RVS1 PSMD1 PTHR10943:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endopeptidase complex#GO:1905369;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;proteasome complex#GO:0000502;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000011810.3|UniProtKB=G3SHV6 G3SHV6 RELA PTHR24169:SF1 NUCLEAR FACTOR NF-KAPPA-B PROTEIN TRANSCRIPTION FACTOR P65 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 response to peptide#GO:1901652;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;response to lipopolysaccharide#GO:0032496;positive regulation of transcription by RNA polymerase II#GO:0045944;intracellular signaling cassette#GO:0141124;response to cytokine#GO:0034097;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;defense response to other organism#GO:0098542;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;non-canonical NF-kappaB signal transduction#GO:0038061;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;response to bacterium#GO:0009617;response to external biotic stimulus#GO:0043207;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;cellular response to molecule of bacterial origin#GO:0071219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;response to other organism#GO:0051707;canonical NF-kappaB signal transduction#GO:0007249;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252;DNA-binding transcription factor#PC00218 Toll receptor signaling pathway#P00054>NFkappaB#P01354;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Apoptosis signaling pathway#P00006>NFkappaB#P00297;Gonadotropin-releasing hormone receptor pathway#P06664>p65#P06702 GORGO|Ensembl=ENSGGOG00000010109.3|UniProtKB=G3SJU6 G3SJU6 MIEF1 PTHR16451:SF12 MITOCHONDRIAL DYNAMICS PROTEINS 49/51 FAMILY MEMBER MITOCHONDRIAL DYNAMICS PROTEIN MIEF1 positive regulation of organelle organization#GO:0010638;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of developmental process#GO:0051094;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of organelle organization#GO:0033043;regulation of mitochondrion organization#GO:0010821;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000014075.3|UniProtKB=A0A2I2YKI6 A0A2I2YKI6 MRPL18 PTHR12899:SF23 39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL18M RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676 transport#GO:0006810;localization#GO:0051179;nucleic acid transport#GO:0050657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025487.2|UniProtKB=G3S6E9 G3S6E9 PTHR12620:SF11 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT SPLICING FACTOR U2AF 35 KDA SUBUNIT RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;pre-mRNA binding#GO:0036002 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000001497.3|UniProtKB=G3QGL9 G3QGL9 LOC101141716 PTHR43943:SF3 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 2, MITOCHONDRIAL catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000005370.3|UniProtKB=G3QRK2 G3QRK2 POLE3 PTHR46172:SF1 DNA POLYMERASE EPSILON SUBUNIT 3 DNA POLYMERASE EPSILON SUBUNIT 3 binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;DNA binding#GO:0003677 response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;epsilon DNA polymerase complex#GO:0008622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000040264.1|UniProtKB=A0A2I2YAG9 A0A2I2YAG9 PTHR24381:SF458 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 697 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000000284.3|UniProtKB=G3QDG2 G3QDG2 MRAP PTHR28675:SF2 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN protein binding#GO:0005515;molecular function regulator activity#GO:0098772;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;regulation of biological process#GO:0050789;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000038588.1|UniProtKB=A0A2I2ZV13 A0A2I2ZV13 ZNF783 PTHR24390:SF192 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 783 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000027623.2|UniProtKB=G3SH88 G3SH88 IGFL4 PTHR34827:SF1 INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3-RELATED INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 GORGO|Ensembl=ENSGGOG00000040987.1|UniProtKB=A0A2I2ZIN3 A0A2I2ZIN3 PTHR11911:SF127 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED IMP DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000027011.2|UniProtKB=G3SBY7 G3SBY7 PTHR24114:SF37 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74B GORGO|Ensembl=ENSGGOG00000028052.2|UniProtKB=A0A2I2YFG0 A0A2I2YFG0 PTHR23138:SF138 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN intracellular transport#GO:0046907;transport#GO:0006810;nucleocytoplasmic transport#GO:0006913;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009781.3|UniProtKB=G3R2V0 G3R2V0 TNKS2 PTHR24180:SF11 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-2 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of telomere maintenance#GO:0032204;intracellular protein localization#GO:0008104;regulation of chromosome organization#GO:0033044;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;positive regulation of DNA metabolic process#GO:0051054;positive regulation of signal transduction#GO:0009967;localization#GO:0051179;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of macromolecule metabolic process#GO:0010604;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;regulation of cellular component organization#GO:0051128;regulation of Wnt signaling pathway#GO:0030111;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase inhibitor#PC00139;kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000016804.3|UniProtKB=G3RKZ1 G3RKZ1 PTHR21325:SF52 PHOSPHOLIPASE B, PLB1 PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;A2-type glycerophospholipase activity#GO:0004623 phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid metabolic process#GO:0006629;cellular process#GO:0009987 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;brush border membrane#GO:0031526;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;brush border#GO:0005903;cell periphery#GO:0071944;membrane#GO:0016020;apical plasma membrane#GO:0016324;cluster of actin-based cell projections#GO:0098862;cell projection membrane#GO:0031253;apical part of cell#GO:0045177 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000009400.3|UniProtKB=G3R1V1 G3R1V1 PTHR35156:SF1 TESTIS-EXPRESSED PROTEIN 52 TESTIS-EXPRESSED PROTEIN 52 GORGO|Ensembl=ENSGGOG00000006540.3|UniProtKB=G3QUJ5 G3QUJ5 CHRNA5 PTHR18945:SF76 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-5 neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;acetylcholine receptor activity#GO:0015464;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 transport#GO:0006810;establishment of localization#GO:0051234;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;modulation of chemical synaptic transmission#GO:0050804;neuromuscular synaptic transmission#GO:0007274;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052 transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA5#P06593;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 GORGO|Ensembl=ENSGGOG00000010567.3|UniProtKB=G3R4V3 G3R4V3 APEH PTHR42776:SF4 SERINE PEPTIDASE S9 FAMILY MEMBER ACYLAMINO-ACID-RELEASING ENZYME catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein modifying enzyme#PC00260;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000012241.3|UniProtKB=G3R968 G3R968 ST6GALNAC2 PTHR45941:SF5 ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2-LIKE-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000040913.1|UniProtKB=A0A2I2YKL9 A0A2I2YKL9 RAB35 PTHR47977:SF76 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-35 GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;intracellular transport#GO:0046907;transport#GO:0006810;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000010088.3|UniProtKB=G3R3L3 G3R3L3 FGF4 PTHR11486:SF31 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 4 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;response to fibroblast growth factor#GO:0071774;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;nervous system development#GO:0007399;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531 extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000012756.3|UniProtKB=G3RAG9 G3RAG9 LOC101147830 PTHR24100:SF56 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 3 MEMBER A3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000014365.3|UniProtKB=A0A2I2ZWM4 A0A2I2ZWM4 NSA2 PTHR12642:SF3 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000016277.3|UniProtKB=G3RJJ8 G3RJJ8 PTHR15742:SF3 GIRDIN MICROTUBULE CROSS-LINKING FACTOR 1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of bipolar cell polarity#GO:0061245;microtubule bundle formation#GO:0001578;cellular component organization or biogenesis#GO:0071840;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;spindle#GO:0005819;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;plasma membrane region#GO:0098590;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;midbody#GO:0030496;spindle pole#GO:0000922;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000039941.1|UniProtKB=A0A2I2ZG73 A0A2I2ZG73 PTHR18919:SF143 ACETYL-COA C-ACYLTRANSFERASE TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000003933.3|UniProtKB=G3QMV8 G3QMV8 KCNMB3 PTHR10258:SF4 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-3 transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;response to calcium ion#GO:0051592;localization#GO:0051179;nervous system process#GO:0050877;metal ion transport#GO:0030001;response to stimulus#GO:0050896;action potential#GO:0001508;detection of chemical stimulus#GO:0009593;system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;response to metal ion#GO:0010038;transport#GO:0006810;biological regulation#GO:0065007;response to chemical#GO:0042221;potassium ion transport#GO:0006813;multicellular organismal process#GO:0032501;cellular process#GO:0009987;detection of stimulus#GO:0051606 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000010489.3|UniProtKB=G3R4M1 G3R4M1 MPG PTHR10429:SF0 DNA-3-METHYLADENINE GLYCOSYLASE DNA-3-METHYLADENINE GLYCOSYLASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA N-glycosylase activity#GO:0019104 DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 DNA glycosylase#PC00010;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000014214.3|UniProtKB=G3RE91 G3RE91 GAN PTHR24412:SF232 KELCH PROTEIN GIGAXONIN ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009354.3|UniProtKB=G3R1Q8 G3R1Q8 CBLN2 PTHR22923:SF50 CEREBELLIN-RELATED CEREBELLIN-2 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011822.3|UniProtKB=G3R836 G3R836 TET1 PTHR23358:SF2 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET1 catalytic activity, acting on DNA#GO:0140097;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000008304.3|UniProtKB=G3QZ18 G3QZ18 ZNF300 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012811.3|UniProtKB=A0A2I2Y785 A0A2I2Y785 LEPROTL1 PTHR12050:SF4 LEPTIN RECEPTOR-RELATED LEPTIN RECEPTOR OVERLAPPING TRANSCRIPT-LIKE 1 endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010632.3|UniProtKB=G3R4Z8 G3R4Z8 MIS12 PTHR14527:SF2 PROTEIN MIS12 HOMOLOG PROTEIN MIS12 HOMOLOG mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle assembly#GO:0070925;organelle fission#GO:0048285;kinetochore organization#GO:0051383;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840 kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000001691.3|UniProtKB=A0A2I2Z2E7 A0A2I2Z2E7 PTHR12391:SF3 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000008994.3|UniProtKB=G3R0U5 G3R0U5 NR5A1 PTHR24086:SF24 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A STEROIDOGENIC FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;tissue development#GO:0009888;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>SF1#P06848 GORGO|Ensembl=ENSGGOG00000005522.3|UniProtKB=G3QRY9 G3QRY9 MAPT PTHR11501:SF14 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN TAU molecular function regulator activity#GO:0098772;cytoskeletal protein binding#GO:0008092;enzyme inhibitor activity#GO:0004857;tubulin binding#GO:0015631;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;microtubule binding#GO:0008017;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;regulation of microtubule-based process#GO:0032886;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;axon#GO:0030424;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000001545.3|UniProtKB=G3QGR4 G3QGR4 COG7 PTHR21443:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7 cellular component organization#GO:0016043;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;Golgi organization#GO:0007030;protein localization to organelle#GO:0033365;endomembrane system organization#GO:0010256;protein localization to Golgi apparatus#GO:0034067;cellular localization#GO:0051641;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;intracellular protein localization#GO:0008104 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;COG complex#GO:0017119;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000038045.1|UniProtKB=A0A2I2ZDJ6 A0A2I2ZDJ6 CENPM PTHR34436:SF1 CENTROMERE PROTEIN M CENTROMERE PROTEIN M intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080 GORGO|Ensembl=ENSGGOG00000011862.3|UniProtKB=G3R872 G3R872 SLC29A4 PTHR10332:SF93 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4 nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;active transmembrane transporter activity#GO:0022804;carbohydrate derivative transmembrane transporter activity#GO:1901505;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015610.3|UniProtKB=G3SF75 G3SF75 MEP1B PTHR10127:SF814 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000002584.3|UniProtKB=G3QJF2 G3QJF2 TACR3 PTHR46925:SF1 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED NEUROMEDIN-K RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 regulation of microtubule-based process#GO:0032886;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;regulation of reproductive process#GO:2000241 9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000015985.3|UniProtKB=A0A2I2YJY8 A0A2I2YJY8 IL36G PTHR10078:SF37 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-36 GAMMA signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;cellular response to molecule of bacterial origin#GO:0071219;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000043959.1|UniProtKB=A0A2I2Z7U1 A0A2I2Z7U1 TEX46 PTHR39412:SF1 TESTIS-EXPRESSED PROTEIN 46 TESTIS-EXPRESSED PROTEIN 46 fertilization#GO:0009566;reproductive process#GO:0022414;single fertilization#GO:0007338;sexual reproduction#GO:0019953 GORGO|Ensembl=ENSGGOG00000003310.3|UniProtKB=A0A2I2Y9U1 A0A2I2Y9U1 FADS6 PTHR19353:SF13 FATTY ACID DESATURASE 2 FATTY ACID DESATURASE 6 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000012825.4|UniProtKB=A0A2I2YQA4 A0A2I2YQA4 SIL1 PTHR19316:SF35 PROTEIN FOLDING REGULATOR NUCLEOTIDE EXCHANGE FACTOR SIL1 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000043735.1|UniProtKB=A0A2I2Y718 A0A2I2Y718 PTHR10497:SF9 60S RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN EL27 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008389.3|UniProtKB=G3QZ92 G3QZ92 TAAR5 PTHR24249:SF307 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 5 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000025750.2|UniProtKB=G3SAD7 G3SAD7 DEFB113 PTHR39411:SF1 BETA-DEFENSIN 113 BETA-DEFENSIN 113 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000007049.3|UniProtKB=G3QVW1 G3QVW1 PTHR21624:SF1 STEROL DESATURASE-RELATED PROTEIN ALKYLGLYCEROL MONOOXYGENASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000024403.2|UniProtKB=G3SHR5 G3SHR5 CTXN2 PTHR16736:SF2 CORTEXIN-1-RELATED CORTEXIN-2 GORGO|Ensembl=ENSGGOG00000003872.3|UniProtKB=G3S8Q9 G3S8Q9 SMN2 PTHR13681:SF33 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL MOTOR NEURON PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;axon development#GO:0061564;macromolecule biosynthetic process#GO:0009059;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;plasma membrane bounded cell projection organization#GO:0120036;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;anatomical structure development#GO:0048856;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;system development#GO:0048731;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;protein-RNA complex organization#GO:0071826;cell projection morphogenesis#GO:0048858;protein-containing complex organization#GO:0043933;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;nucleic acid biosynthetic process#GO:0141187;generation of neurons#GO:0048699;RNA metabolic process#GO:0016070;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;anatomical structure morphogenesis#GO:0009653;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;mRNA metabolic process#GO:0016071;cell development#GO:0048468;ribonucleoprotein complex biogenesis#GO:0022613 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;membrane-bounded organelle#GO:0043227;SMN complex#GO:0032797;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000007700.3|UniProtKB=G3QXJ0 G3QXJ0 PTHR10438:SF107 THIOREDOXIN THIOREDOXIN DOMAIN-CONTAINING PROTEIN 2 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 flagellated sperm motility#GO:0030317;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;cellular homeostasis#GO:0019725;microtubule-based process#GO:0007017;cell redox homeostasis#GO:0045454;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;sperm motility#GO:0097722;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;homeostatic process#GO:0042592 cell projection#GO:0042995;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Oxidative stress response#P00046>TRX#P01122 GORGO|Ensembl=ENSGGOG00000004720.3|UniProtKB=G3QPW8 G3QPW8 TMEM237 PTHR28388:SF1 TRANSMEMBRANE PROTEIN 237 TRANSMEMBRANE PROTEIN 237 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000013159.3|UniProtKB=G3SA61 G3SA61 C3 PTHR11412:SF81 MACROGLOBULIN / COMPLEMENT COMPLEMENT C3 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of immune response#GO:0050776;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;humoral immune response#GO:0006959;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;defense response to other organism#GO:0098542;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;complement activation#GO:0006956;immune response#GO:0006955;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950 extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000005649.3|UniProtKB=G3QSA0 G3QSA0 C2orf69 PTHR31296:SF1 UPF0565 PROTEIN C2ORF69 MITOCHONDRIAL PROTEIN C2ORF69 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000001465.3|UniProtKB=G3QGI7 G3QGI7 ST6GALNAC3 PTHR23136:SF8 TAX1-BINDING PROTEIN 3-RELATED ALPHA-N-ACETYLNEURAMINYL-2,3-BETA-GALACTOSYL-1,3-N-ACETYLGALACTOSAMINIDE6-ALPHA-SIALYLTRANSFERASE GORGO|Ensembl=ENSGGOG00000027223.2|UniProtKB=G3SCJ1 G3SCJ1 OSGEPL1 PTHR11735:SF6 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000015279.3|UniProtKB=G3RGZ2 G3RGZ2 RPS19 PTHR11710:SF32 40S RIBOSOMAL PROTEIN S19 SMALL RIBOSOMAL SUBUNIT PROTEIN ES19 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016877.3|UniProtKB=G3RZR7 G3RZR7 OSR1 PTHR14196:SF5 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;kidney development#GO:0001822;renal system development#GO:0072001;negative regulation of macromolecule biosynthetic process#GO:0010558 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000008247.3|UniProtKB=G3SHY8 G3SHY8 PTHR24028:SF133 CADHERIN-87A PROTOCADHERIN ALPHA-9 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000009979.3|UniProtKB=A0A2I2YU98 A0A2I2YU98 DYNLT1 PTHR21255:SF19 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 1 binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000007334.3|UniProtKB=G3QWM7 G3QWM7 PDS5A PTHR12663:SF2 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG A chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000039236.1|UniProtKB=A0A2I2Y417 A0A2I2Y417 CIAPIN1 PTHR13273:SF16 ANAMORSIN ANAMORSIN iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000012607.3|UniProtKB=G3RA52 G3RA52 PLEKHH2 PTHR22903:SF3 PLEKHH PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 2 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin cytoskeleton organization#GO:0032956;regulation of protein-containing complex disassembly#GO:0043244;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000000668.3|UniProtKB=G3QEG3 G3QEG3 ARHGEF3 PTHR46006:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000011429.3|UniProtKB=G3SFU6 G3SFU6 LOC101127500 PTHR23049:SF74 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 12A cytoskeletal protein binding#GO:0008092;binding#GO:0005488;myosin binding#GO:0017022;protein binding#GO:0005515 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000009728.3|UniProtKB=A0A2I2Y2M1 A0A2I2Y2M1 CALD1 PTHR18949:SF0 CALDESMON CALDESMON protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;myosin binding#GO:0017022 cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000006894.3|UniProtKB=G3QVH6 G3QVH6 KHDC1 PTHR31368:SF6 DEVELOPMENT PLURPOTENCY-ASSOCIATED PROTEIN 1/5 FAMILY MEMBER KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000009309.3|UniProtKB=A0A2I2Y7T9 A0A2I2Y7T9 TRIM46 PTHR24099:SF20 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 46 neuron migration#GO:0001764;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;anterograde synaptic vesicle transport#GO:0048490;neurogenesis#GO:0022008;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;cell migration#GO:0016477;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axo-dendritic transport#GO:0008088;axon development#GO:0061564;vesicle localization#GO:0051648;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;anterograde axonal transport#GO:0008089;axonal transport#GO:0098930;organelle localization#GO:0051640;microtubule bundle formation#GO:0001578;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;synaptic vesicle localization#GO:0097479;cytoskeleton organization#GO:0007010;establishment of vesicle localization#GO:0051650;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle organization#GO:0006996;neuron projection development#GO:0031175;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular localization#GO:0051641;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;establishment of organelle localization#GO:0051656;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection#GO:0043005;main axon#GO:0044304;axon#GO:0030424 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000009578.3|UniProtKB=G3R2A7 G3R2A7 TMEM61 PTHR37151:SF1 TRANSMEMBRANE PROTEIN 61 TRANSMEMBRANE PROTEIN 61 GORGO|Ensembl=ENSGGOG00000014250.3|UniProtKB=G3REC5 G3REC5 CLCN3 PTHR45711:SF8 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 3 channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 vesicle organization#GO:0016050;cellular homeostasis#GO:0019725;synaptic vesicle maturation#GO:0016188;proton transmembrane transport#GO:1902600;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;chloride transport#GO:0006821;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;developmental maturation#GO:0021700;vesicle-mediated transport#GO:0016192;monoatomic anion transmembrane transport#GO:0098656;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular localization#GO:0051641;transmembrane transport#GO:0055085;homeostatic process#GO:0042592;monoatomic anion transport#GO:0006820;cellular component organization#GO:0016043 bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;lytic vacuole#GO:0000323;vacuole#GO:0005773;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;lysosomal membrane#GO:0005765;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;Golgi apparatus#GO:0005794;plasma membrane#GO:0005886;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;synaptic vesicle#GO:0008021 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000008012.3|UniProtKB=G3QYA4 G3QYA4 MHC-G PTHR16675:SF297 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN G protein binding#GO:0005515;antigen binding#GO:0003823;peptide binding#GO:0042277;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000022636.2|UniProtKB=A0A2I2ZRJ5 A0A2I2ZRJ5 SUMO3 PTHR10562:SF108 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 2 binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011867.3|UniProtKB=A1YEX3 A1YEX3 ZBTB25 PTHR24399:SF28 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 25 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000023276.2|UniProtKB=G3SDF4 G3SDF4 PTHR12586:SF1 CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL transferase#PC00220 GORGO|Ensembl=ENSGGOG00000037490.1|UniProtKB=A0A2I2Y3K3 A0A2I2Y3K3 PTHR24067:SF396 UBIQUITIN-CONJUGATING ENZYME E2 UBC CORE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA metabolic process#GO:0006259;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008427.3|UniProtKB=A0A2I2ZTW8 A0A2I2ZTW8 TRPM4 PTHR13800:SF6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 4 passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;monoatomic cation transmembrane transporter activity#GO:0008324 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014319.3|UniProtKB=G3REI5 G3REI5 RECQL4 PTHR13710:SF167 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q4 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138 organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;telomere maintenance#GO:0000723;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;telomere organization#GO:0032200 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA helicase#PC00011 GORGO|Ensembl=ENSGGOG00000010776.4|UniProtKB=A0A2I2Z3K6 A0A2I2Z3K6 IDE PTHR43690:SF41 NARDILYSIN INSULIN-DEGRADING ENZYME metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 biological regulation#GO:0065007;hormone metabolic process#GO:0042445;catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;regulation of biological quality#GO:0065008;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule catabolic process#GO:0009057 intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;microbody#GO:0042579;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;cytosol#GO:0005829 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000012176.3|UniProtKB=G3R913 G3R913 TADA2A PTHR12374:SF85 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-ALPHA transcription coactivator activity#GO:0003713;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000000190.3|UniProtKB=G3RVH1 G3RVH1 INTS10 PTHR16055:SF2 INTEGRATOR COMPLEX SUBUNIT 10 INTEGRATOR COMPLEX SUBUNIT 10 snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;integrator complex#GO:0032039;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000037854.1|UniProtKB=A0A2I2YME9 A0A2I2YME9 LOC101142088 PTHR23341:SF1 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP PROTEIN HMG-I_HMG-Y DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488 signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000014011.3|UniProtKB=G3RDQ5 G3RDQ5 CLEC19A PTHR22802:SF459 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN CONTAINING 19A molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012077.3|UniProtKB=G3R8S0 G3R8S0 TULP4 PTHR16517:SF2 TUBBY-RELATED TUBBY-RELATED PROTEIN 4 macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;localization#GO:0051179 plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012065.3|UniProtKB=G3S7Y2 G3S7Y2 SREBF2 PTHR46062:SF3 STEROL REGULATORY ELEMENT-BINDING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of localization#GO:0032879;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000024326.2|UniProtKB=G3SBR6 G3SBR6 ZC2HC1C PTHR14649:SF1 ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C GORGO|Ensembl=ENSGGOG00000009130.3|UniProtKB=G3R169 G3R169 TPM1 PTHR19269:SF41 TROPOMYOSIN TROPOMYOSIN ALPHA-1 CHAIN actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 circulatory system process#GO:0003013;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;heart process#GO:0003015;muscle system process#GO:0003012;actin cytoskeleton organization#GO:0030036;striated muscle contraction#GO:0006941;muscle contraction#GO:0006936;cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;heart contraction#GO:0060047;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;cytoskeleton organization#GO:0007010 actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000014331.3|UniProtKB=G3RVT1 G3RVT1 NOP16 PTHR13243:SF1 HSPC111 PROTEIN-RELATED NUCLEOLAR PROTEIN 16 cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000023009.2|UniProtKB=G3RTC2 G3RTC2 MPZL2 PTHR13869:SF21 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 2 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000010932.3|UniProtKB=G3R5S7 G3R5S7 SMG5 PTHR15696:SF39 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG5 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007892.3|UniProtKB=G3QY02 G3QY02 CLEC4D PTHR22802:SF11 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER D carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;defense response to fungus#GO:0050832;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013788.3|UniProtKB=G3RD56 G3RD56 HSF5 PTHR10015:SF278 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 5 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000036879.1|UniProtKB=G3SAK6 G3SAK6 ZNF675 PTHR24406:SF11 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED DNA-BINDING PROTEIN REPIN1 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003324.3|UniProtKB=G3S237 G3S237 GLIPR2 PTHR10334:SF581 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1 positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000036480.1|UniProtKB=P40252 P40252 PRNP PTHR15506:SF2 DOPPEL PRION MAJOR PRION PROTEIN molecular condensate scaffold activity#GO:0140693;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;molecular adaptor activity#GO:0060090;copper ion binding#GO:0005507 cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;positive regulation of calcium-mediated signaling#GO:0050850;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;positive regulation of intracellular signal transduction#GO:1902533;response to metal ion#GO:0010038;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 membrane#GO:0016020;membrane raft#GO:0045121;cell periphery#GO:0071944;membrane microdomain#GO:0098857;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000010979.3|UniProtKB=G3R5X2 G3R5X2 EIF2B4 PTHR10233:SF14 TRANSLATION INITIATION FACTOR EIF-2B TRANSLATION INITIATION FACTOR EIF2B SUBUNIT DELTA translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;guanyl-nucleotide exchange factor complex#GO:0032045;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535 translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000004423.3|UniProtKB=G3S3I8 G3S3I8 HADH PTHR43561:SF3 FAMILY NOT NAMED HYDROXYACYL-COENZYME A DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000009076.3|UniProtKB=G3R126 G3R126 PRKAA2 PTHR24343:SF303 SERINE/THREONINE KINASE 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 negative regulation of TORC1 signaling#GO:1904262;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of signal transduction#GO:0009968;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;intracellular protein localization#GO:0008104;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;macromolecule localization#GO:0033036;cellular response to glucose starvation#GO:0042149;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;localization#GO:0051179;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646 protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway by glucose deprivation#P04397>AMPK#P04639 GORGO|Ensembl=ENSGGOG00000003475.3|UniProtKB=G3QLQ9 G3QLQ9 OSBP2 PTHR10972:SF194 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 2 alcohol binding#GO:0043178;cholesterol binding#GO:0015485;steroid binding#GO:0005496;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000009856.3|UniProtKB=G3R330 G3R330 ADCY10 PTHR16305:SF32 TESTICULAR SOLUBLE ADENYLYL CYCLASE ADENYLATE CYCLASE TYPE 10 phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AC#P01082;Metabotropic glutamate receptor group III pathway#P00039>AC#P01043;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Metabotropic glutamate receptor group II pathway#P00040>AC#P01052 GORGO|Ensembl=ENSGGOG00000015303.3|UniProtKB=G3RH34 G3RH34 INTS1 PTHR21224:SF1 INTEGRATOR COMPLEX SUBUNIT 1 INTEGRATOR COMPLEX SUBUNIT 1 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;catabolic process#GO:0009056;snRNA 3'-end processing#GO:0034472;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleobase-containing compound catabolic process#GO:0034655;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;snRNA processing#GO:0016180 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;integrator complex#GO:0032039;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000007313.3|UniProtKB=G3S236 G3S236 PHTF2 PTHR12680:SF2 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF PROTEIN PHTF2 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000009575.3|UniProtKB=A0A2I2ZJL0 A0A2I2ZJL0 CEPT1 PTHR10414:SF27 ETHANOLAMINEPHOSPHOTRANSFERASE CHOLINE_ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000008901.3|UniProtKB=G3R0L6 G3R0L6 NFKBIE PTHR24118:SF37 POTE ANKYRIN DOMAIN NF-KAPPA-B INHIBITOR EPSILON protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 Toll receptor signaling pathway#P00054>IkappaB#P01338;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859 GORGO|Ensembl=ENSGGOG00000027251.2|UniProtKB=G3SDQ9 G3SDQ9 MRPL20 PTHR10986:SF16 39S RIBOSOMAL PROTEIN L20 LARGE RIBOSOMAL SUBUNIT PROTEIN BL20M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011177.3|UniProtKB=G3R6E4 G3R6E4 CCDC70 PTHR21533:SF22 LEUCINE-RICH PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 70 GORGO|Ensembl=ENSGGOG00000014103.3|UniProtKB=G3RRR5 G3RRR5 NPFFR1 PTHR24241:SF4 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007756.3|UniProtKB=G3QXN2 G3QXN2 MBNL3 PTHR12675:SF3 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000004821.3|UniProtKB=G3QQ65 G3QQ65 SLC45A2 PTHR19432:SF34 SUGAR TRANSPORTER MEMBRANE-ASSOCIATED TRANSPORTER PROTEIN monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324;solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293 cellular process#GO:0009987;developmental pigmentation#GO:0048066;phenol-containing compound metabolic process#GO:0018958;pigment metabolic process#GO:0042440;phenol-containing compound biosynthetic process#GO:0046189;biosynthetic process#GO:0009058;pigment biosynthetic process#GO:0046148;pigmentation#GO:0043473;secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;secondary metabolic process#GO:0019748;melanin biosynthetic process#GO:0042438 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;melanosome#GO:0042470;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000013880.3|UniProtKB=A0A2I2ZG74 A0A2I2ZG74 VPS8 PTHR12616:SF16 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;vesicle fusion#GO:0006906;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;transport#GO:0006810;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013997.3|UniProtKB=G3RDP4 G3RDP4 RPUSD1 PTHR21600:SF94 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD1 intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000001034.3|UniProtKB=G3RNR8 G3RNR8 SNRNP40 PTHR44006:SF1 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 mRNA splicing#P00058>U5#P01474 GORGO|Ensembl=ENSGGOG00000008862.3|UniProtKB=G3R0H7 G3R0H7 PTHR11188:SF16 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 4 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000010107.3|UniProtKB=G3SGI8 G3SGI8 MGAT3 PTHR12224:SF0 BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;metabolic process#GO:0008152;amino sugar metabolic process#GO:0006040 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000041291.1|UniProtKB=A0A2I2Z4B2 A0A2I2Z4B2 PTHR48082:SF1 ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT ALPHA, MITOCHONDRIAL transporter activity#GO:0005215;ligase activity#GO:0016874;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;proton transmembrane transporter activity#GO:0015078;monoatomic ion channel activity#GO:0005216;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;channel activity#GO:0015267 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803 primary active transporter#PC00068;ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000023833.2|UniProtKB=G3S597 G3S597 CCDC80 PTHR46792:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of cell adhesion#GO:0045785;cellular process#GO:0009987;cellular component organization#GO:0016043;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009692.3|UniProtKB=A0A2I2YQG1 A0A2I2YQG1 DAND5 PTHR15273:SF5 DAN DOMAIN FAMILY MEMBER 5 DAN DOMAIN FAMILY MEMBER 5 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;determination of left/right symmetry#GO:0007368;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;specification of symmetry#GO:0009799;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regionalization#GO:0003002;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anterior/posterior axis specification#GO:0009948;anterior/posterior pattern specification#GO:0009952;left/right pattern formation#GO:0060972;heart development#GO:0007507;determination of bilateral symmetry#GO:0009855;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040670.1|UniProtKB=A0A2I2ZWE7 A0A2I2ZWE7 PTHR32428:SF4 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED PROLINE-RICH PROTEIN 5 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;TOR signaling#GO:0031929;positive regulation of response to stimulus#GO:0048584;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;TORC2 signaling#GO:0038203;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of signaling#GO:0023056 intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201;protein-containing complex#GO:0032991 PDGF signaling pathway#P00047>Rho#P01174;VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520 GORGO|Ensembl=ENSGGOG00000013537.3|UniProtKB=G3SEM0 G3SEM0 DDI2 PTHR12917:SF13 ASPARTYL PROTEASE DDI-RELATED PROTEIN DDI1 HOMOLOG 2 catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein catabolic process#GO:0030163;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule catabolic process#GO:0009057;regulation of biological quality#GO:0065008;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;regulation of protein stability#GO:0031647;cellular process#GO:0009987;primary metabolic process#GO:0044238;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;aspartic protease#PC00053 GORGO|Ensembl=ENSGGOG00000005949.3|UniProtKB=G3QT20 G3QT20 FCSK PTHR32463:SF0 L-FUCOSE KINASE L-FUCOSE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 transferase#PC00220;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000001220.3|UniProtKB=G3QFW9 G3QFW9 DDX28 PTHR24031:SF421 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX28-RELATED cellular component assembly#GO:0022607;cellular process#GO:0009987;ribosomal large subunit assembly#GO:0000027;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;mitochondrial large ribosomal subunit assembly#GO:1902775;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000007994.3|UniProtKB=G3QY90 G3QY90 AURKC PTHR24350:SF3 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE C transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 microtubule cytoskeleton organization#GO:0000226;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;kinetochore#GO:0000776;spindle pole#GO:0000922;midbody#GO:0030496;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015991.3|UniProtKB=G3RIS9 G3RIS9 IL36A PTHR10078:SF25 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-36 ALPHA signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 cellular response to molecule of bacterial origin#GO:0071219;defense response#GO:0006952;response to external stimulus#GO:0009605;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to peptide#GO:1901652;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;interleukin superfamily#PC00128;intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 GORGO|Ensembl=ENSGGOG00000015404.3|UniProtKB=G3RHA8 G3RHA8 CCDC3 PTHR31663:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of gene expression#GO:0010629;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013899.3|UniProtKB=G3RDE9 G3RDE9 C5H6orf52 PTHR37457:SF1 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 52 tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;post-transcriptional regulation of gene expression#GO:0010608;metabolic process#GO:0008152;translational elongation#GO:0006414;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;protein biosynthetic process#GO:0160307;regulation of macromolecule metabolic process#GO:0060255;translation#GO:0006412;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000488.3|UniProtKB=G3RX40 G3RX40 BRSK1 PTHR24343:SF130 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE BRSK1 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;generation of neurons#GO:0048699;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;mitotic cell cycle process#GO:1903047;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;mitotic cell cycle phase transition#GO:0044772;system development#GO:0048731;anatomical structure development#GO:0048856;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011679.3|UniProtKB=G3RQM6 G3RQM6 TSR3 PTHR20426:SF0 RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG 18S RRNA AMINOCARBOXYPROPYLTRANSFERASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on RNA#GO:0140098 rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000010762.3|UniProtKB=G3R5D1 G3R5D1 SHKBP1 PTHR15859:SF5 SETA BINDING PROTEIN 1 SH3KBP1-BINDING PROTEIN 1 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of response to stimulus#GO:0048584;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of signal transduction#GO:0009967;positive regulation of biological process#GO:0048518;regulation of ERBB signaling pathway#GO:1901184;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003717.3|UniProtKB=G3RVE3 G3RVE3 COL27A1 PTHR24023:SF844 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXVII) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000005804.3|UniProtKB=A0A2I2YV69 A0A2I2YV69 TMEM9 PTHR13064:SF1 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER PROTON-TRANSPORTING V-TYPE ATPASE COMPLEX ASSEMBLY REGULATOR TMEM9 GORGO|Ensembl=ENSGGOG00000015207.3|UniProtKB=G3RGT0 G3RGT0 IQCN PTHR22590:SF2 MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN IQ DOMAIN-CONTAINING PROTEIN N GORGO|Ensembl=ENSGGOG00000026078.2|UniProtKB=A0A2I2ZAR5 A0A2I2ZAR5 CCDC184 PTHR31554:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 184 COILED-COIL DOMAIN-CONTAINING PROTEIN 184 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003410.3|UniProtKB=G3QLK1 G3QLK1 SYMPK PTHR15245:SF20 SYMPLEKIN-RELATED SYMPLEKIN nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002419.3|UniProtKB=G3QJ04 G3QJ04 CPA1 PTHR11705:SF94 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A1 exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000005192.3|UniProtKB=A0A2I2YRN3 A0A2I2YRN3 CDADC1 PTHR11086:SF14 DEOXYCYTIDYLATE DEAMINASE-RELATED DCTP DEAMINASE catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;deaminase#PC00088 GORGO|Ensembl=ENSGGOG00000009934.3|UniProtKB=G3R379 G3R379 ADCK1 PTHR43173:SF19 ABC1 FAMILY PROTEIN AARF DOMAIN-CONTAINING PROTEIN KINASE 1 chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;homeostatic process#GO:0042592;mitochondrion organization#GO:0007005 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000007590.3|UniProtKB=G3SB67 G3SB67 GLS PTHR12544:SF49 GLUTAMINASE GLUTAMINASE KIDNEY ISOFORM, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000007729.3|UniProtKB=Q0MQG4 Q0MQG4 NDUFS2 PTHR11993:SF48 NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055;NADH dehydrogenase activity#GO:0003954;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824 cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000028316.2|UniProtKB=G3RVC7 G3RVC7 PTHR47831:SF1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2A-RELATED nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000014804.3|UniProtKB=G3S2X6 G3S2X6 TRIM5 PTHR24103:SF416 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 5 binding#GO:0005488;kinase binding#GO:0019900;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787;protein kinase binding#GO:0019901;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;identical protein binding#GO:0042802;aminoacyltransferase activity#GO:0016755 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of localization#GO:0032879;defense response to other organism#GO:0098542;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;positive regulation of signaling#GO:0023056;regulation of protein localization#GO:0032880;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;positive regulation of signal transduction#GO:0009967 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000010867.3|UniProtKB=G3R5L1 G3R5L1 PTHR13976:SF32 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN F nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000039562.1|UniProtKB=A0A2I2ZU28 A0A2I2ZU28 PTHR23267:SF141 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 38-1 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000026588.2|UniProtKB=G3RVQ9 G3RVQ9 PTHR18945:SF907 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-7 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324 anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;metal ion transport#GO:0030001;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell body#GO:0044297;postsynapse#GO:0098794;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495;axon#GO:0030424;postsynaptic membrane#GO:0045211;presynaptic membrane#GO:0042734;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;presynapse#GO:0098793;membrane#GO:0016020;transporter complex#GO:1990351;cell junction#GO:0030054;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079 GORGO|Ensembl=ENSGGOG00000027176.2|UniProtKB=G3RMY0 G3RMY0 SSU72L6 PTHR20383:SF12 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 LIKE PROTEIN 6 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;termination of RNA polymerase II transcription#GO:0006369;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000023494.2|UniProtKB=G3RTJ0 G3RTJ0 PTHR24072:SF13 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOQ protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;transport#GO:0006810;actin filament organization#GO:0007015;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein#PC00020;small GTPase#PC00208 Huntington disease#P00029>Rac#P00775;EGF receptor signaling pathway#P00018>Rac#P00564 GORGO|Ensembl=ENSGGOG00000009783.3|UniProtKB=G3R2U3 G3R2U3 BACC1 PTHR21397:SF2 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED BPTF-ASSOCIATED CHROMATIN COMPLEX COMPONENT 1 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ISWI-type complex#GO:0031010;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000272.3|UniProtKB=G3QDF0 G3QDF0 RBP3 PTHR11261:SF3 INTERPHOTORECEPTOR RETINOID-BINDING PROTEIN RETINOL-BINDING PROTEIN 3 alcohol binding#GO:0043178;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000041965.1|UniProtKB=A0A2I2Y8Q9 A0A2I2Y8Q9 PTHR11431:SF37 FERRITIN FERRITIN HEAVY CHAIN ferrous iron binding#GO:0008198;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000005532.3|UniProtKB=G3QS01 G3QS01 SPATS1 PTHR35845:SF1 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 1 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000036655.1|UniProtKB=A0A2I2ZM28 A0A2I2ZM28 SS18L2 PTHR48617:SF1 FAMILY NOT NAMED SS18-LIKE PROTEIN 2 GORGO|Ensembl=ENSGGOG00000011804.3|UniProtKB=G3R815 G3R815 ORC6 PTHR13394:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808;membraneless organelle#GO:0043228;nuclear origin of replication recognition complex#GO:0005664 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 GORGO|Ensembl=ENSGGOG00000010659.3|UniProtKB=G3S7W5 G3S7W5 DCP1B PTHR16290:SF5 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 MRNA-DECAPPING ENZYME 1B RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA catabolic process#GO:0006401;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 mRNA capping factor#PC00145;RNA processing factor#PC00147 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 GORGO|Ensembl=ENSGGOG00000038472.1|UniProtKB=A0A2I2ZMX3 A0A2I2ZMX3 ZNF460 PTHR24384:SF15 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 460 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010374.3|UniProtKB=A0A2I2ZXQ0 A0A2I2ZXQ0 RANBP17 PTHR12596:SF8 EXPORTIN 4,7-RELATED RAN-BINDING PROTEIN 17 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;protein export from nucleus#GO:0006611;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000042746.1|UniProtKB=A0A2I2YWU9 A0A2I2YWU9 PTHR23267:SF379 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-24-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000345.3|UniProtKB=G3QDL7 G3QDL7 C2CD3 PTHR21254:SF1 C2 DOMAIN-CONTAINING PROTEIN 3 C2 DOMAIN-CONTAINING PROTEIN 3 microtubule cytoskeleton organization#GO:0000226;protein localization to microtubule organizing center#GO:1905508;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;centriole replication#GO:0007099;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cytoskeleton#GO:0044380;cilium assembly#GO:0060271;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;cell cycle process#GO:0022402;protein localization to centrosome#GO:0071539;centrosome cycle#GO:0007098;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to microtubule cytoskeleton#GO:0072698;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031 cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriolar satellite#GO:0034451;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000042996.1|UniProtKB=A0A2I2Z627 A0A2I2Z627 LOC109025864 PTHR12010:SF26 40S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN US14 cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;zinc ion binding#GO:0008270 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000039048.1|UniProtKB=A0A2I2YGM4 A0A2I2YGM4 LOC109028840 PTHR23410:SF24 RIBOSOMAL PROTEIN L5-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL18 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;ribosomal large subunit assembly#GO:0000027;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of biosynthetic process#GO:0009891;protein-RNA complex assembly#GO:0022618;positive regulation of translation#GO:0045727;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;positive regulation of protein metabolic process#GO:0051247 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001913.3|UniProtKB=G3QHP9 G3QHP9 ZNF239 PTHR23226:SF189 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 239 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003255.3|UniProtKB=G3QL53 G3QL53 COMMD2 PTHR15857:SF0 COMM DOMAIN CONTAINING PROTEIN 2 COMM DOMAIN-CONTAINING PROTEIN 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000001427.3|UniProtKB=G3QGF5 G3QGF5 KLK10 PTHR24271:SF66 KALLIKREIN-RELATED KALLIKREIN-10 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000008681.3|UniProtKB=G3R011 G3R011 GAR1 PTHR23237:SF10 NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;binding#GO:0005488 RNA-templated DNA biosynthetic process#GO:0006278;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule modification#GO:0043412;telomere organization#GO:0032200;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;gene expression#GO:0010467;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001773.3|UniProtKB=G3QHC1 G3QHC1 LYPLAL1 PTHR10655:SF74 LYSOPHOSPHOLIPASE-RELATED LYSOPHOSPHOLIPASE-LIKE PROTEIN 1 hydrolase activity#GO:0016787;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;biological regulation#GO:0065007;negative regulation of protein transport#GO:0051224;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;regulation of vesicle-mediated transport#GO:0060627;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phospholipase#PC00186;lipase#PC00143 GORGO|Ensembl=ENSGGOG00000040882.1|UniProtKB=G3R311 G3R311 RETNLB PTHR21101:SF13 RESISTIN RESISTIN-LIKE BETA signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179 cellular process#GO:0009987;cell population proliferation#GO:0008283;epithelial cell proliferation#GO:0050673 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002416.3|UniProtKB=G3QJ02 G3QJ02 AOC1 PTHR10638:SF3 COPPER AMINE OXIDASE DIAMINE OXIDASE [COPPER-CONTAINING] oxidoreductase activity#GO:0016491;copper ion binding#GO:0005507;catalytic activity#GO:0003824;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 biogenic amine metabolic process#GO:0006576;metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 oxidase#PC00175;oxidoreductase#PC00176 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 GORGO|Gene=1A01_GORGO|UniProtKB=P30375 P30375 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN signaling receptor binding#GO:0005102;binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277;protein binding#GO:0005515 positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000037985.1|UniProtKB=A0A2I2YYB2 A0A2I2YYB2 BET1L PTHR12791:SF37 GOLGI SNARE BET1-RELATED BET1-LIKE PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 cellular localization#GO:0051641;localization#GO:0051179;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;regulation of transport#GO:0051049;endosomal transport#GO:0016197;regulation of localization#GO:0032879;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007 membrane protein complex#GO:0098796;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165 SNARE protein#PC00034 GORGO|Ensembl=ENSGGOG00000023376.2|UniProtKB=G3S4F8 G3S4F8 IFIT1B PTHR10271:SF38 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS PROTEIN IFIT1 HOMOLOG B RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 immune system process#GO:0002376;response to virus#GO:0009615;response to peptide#GO:1901652;defense response to virus#GO:0051607;antiviral innate immune response#GO:0140374;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to other organism#GO:0051707 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000004232.3|UniProtKB=G3QNN4 G3QNN4 MPZL3 PTHR13869:SF20 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000010430.3|UniProtKB=G3R4I0 G3R4I0 PTHR45971:SF2 PHOX (PX) DOMAIN-CONTAINING PROTEIN PROTEIN ASSOCIATED WITH UVRAG AS AUTOPHAGY ENHANCER phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;vesicle fusion#GO:0006906;catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;localization#GO:0051179;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;transport#GO:0006810;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000011982.3|UniProtKB=A0A2I2ZPH7 A0A2I2ZPH7 RWDD4 PTHR21275:SF1 RWD DOMAIN-CONTAINING PROTEIN 4 RWD DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000009742.3|UniProtKB=G3R2Q6 G3R2Q6 ARHGDIG PTHR10980:SF8 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 3 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000000556.3|UniProtKB=G3QE61 G3QE61 PTHR12241:SF154 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL11 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;tubulin binding#GO:0015631;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000012103.3|UniProtKB=G3R8U0 G3R8U0 CCDC81 PTHR14362:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001966.3|UniProtKB=G3SCQ5 G3SCQ5 LAT PTHR15586:SF0 LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1 LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor complex adaptor activity#GO:0030159 immune response-regulating signaling pathway#GO:0002764;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;regulation of T cell activation#GO:0050863;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;inflammatory response#GO:0006954;cell communication#GO:0007154;immune response#GO:0006955;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;defense response#GO:0006952 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 T cell activation#P00053>LAT#P01325 GORGO|Ensembl=ENSGGOG00000003991.3|UniProtKB=G3QN16 G3QN16 CALCRL PTHR45620:SF21 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000017019.3|UniProtKB=G3S9C0 G3S9C0 LOC101134050 PTHR48018:SF65 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D14 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008336.3|UniProtKB=A0A2I2YZH3 A0A2I2YZH3 FGFR2 PTHR24416:SF130 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 2 transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;fibroblast growth factor binding#GO:0017134;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740 response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;tube development#GO:0035295;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;angiogenesis#GO:0001525;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;blood vessel morphogenesis#GO:0048514;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 GORGO|Ensembl=ENSGGOG00000001175.3|UniProtKB=G3SB73 G3SB73 SEPTIN7 PTHR18884:SF137 SEPTIN SEPTIN-7 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;intracellular protein localization#GO:0008104;cytokinesis#GO:0000910;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000015080.3|UniProtKB=G3RGG8 G3RGG8 PRLH PTHR17206:SF1 PROLACTIN-RELEASING PEPTIDE PROLACTIN-RELEASING PEPTIDE signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;neuropeptide hormone activity#GO:0005184 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;feeding behavior#GO:0007631 GORGO|Ensembl=ENSGGOG00000002644.3|UniProtKB=A0A2I2ZYR0 A0A2I2ZYR0 INPP5J PTHR11200:SF127 INOSITOL 5-PHOSPHATASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 5-PHOSPHATASE A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of microtubule polymerization or depolymerization#GO:0031110;negative regulation of cellular process#GO:0048523;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of cytoskeleton organization#GO:0051494;regulation of microtubule polymerization#GO:0031113;negative regulation of protein-containing complex assembly#GO:0031333;regulation of microtubule-based process#GO:0032886;negative regulation of protein polymerization#GO:0032272 ruffle#GO:0001726;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000016149.3|UniProtKB=G3RJ76 G3RJ76 SPARC PTHR13866:SF6 SPARC OSTEONECTIN SPARC calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;ear development#GO:0043583;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;regulation of synapse organization#GO:0050807;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;embryo development#GO:0009790;tube development#GO:0035295;inner ear morphogenesis#GO:0042472;inner ear development#GO:0048839;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;sensory organ development#GO:0007423;developmental process#GO:0032502 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000037003.1|UniProtKB=A0A2I2ZU78 A0A2I2ZU78 TNFRSF10C PTHR46330:SF13 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10A-RELATED signaling#GO:0023052;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;cell death#GO:0008219;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;cell communication#GO:0007154;biological regulation#GO:0065007;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;apoptotic signaling pathway#GO:0097190;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TRAIL-R#P00276;p53 pathway#P00059>KILLER/DR5#G01568 GORGO|Ensembl=ENSGGOG00000003368.3|UniProtKB=G3RQC0 G3RQC0 SNPH PTHR12585:SF19 SCC1 / RAD21 FAMILY MEMBER DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 response to stress#GO:0006950;organelle organization#GO:0006996;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;sister chromatid cohesion#GO:0007062 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000026627.2|UniProtKB=A0A2I2Z4R7 A0A2I2Z4R7 PTHR42757:SF12 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED IGLON FAMILY MEMBER 5 regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;regulation of biological process#GO:0050789;cell-cell adhesion#GO:0098609;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000040132.1|UniProtKB=A0A2I2Z078 A0A2I2Z078 G0S2 PTHR15570:SF2 G0/G1 SWITCH PROTEIN 2 G0_G1 SWITCH PROTEIN 2 cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000024779.2|UniProtKB=A0A2I2ZRA7 A0A2I2ZRA7 PTHR45616:SF26 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 8 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actomyosin structure organization#GO:0031032;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000023347.2|UniProtKB=G3SIR4 G3SIR4 LOC101147253 PTHR16716:SF0 CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000002039.3|UniProtKB=G3S5R8 G3S5R8 PTHR24388:SF47 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 280A RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000011892.3|UniProtKB=G3SGZ1 G3SGZ1 CENPU PTHR32222:SF1 CENTROMERE PROTEIN U CENTROMERE PROTEIN U nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007917.3|UniProtKB=G3QY22 G3QY22 PAGE1 PTHR14047:SF3 P ANTIGEN FAMILY MEMBER 5-RELATED P ANTIGEN FAMILY MEMBER 1 GORGO|Ensembl=ENSGGOG00000015551.3|UniProtKB=A0A2I2Z806 A0A2I2Z806 P4HA1 PTHR10869:SF101 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012290.3|UniProtKB=G3R9B1 G3R9B1 ASTL PTHR10127:SF855 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING ASTACIN-LIKE METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 sexual reproduction#GO:0019953;cell activation#GO:0001775;regulation of reproductive process#GO:2000241;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;fertilization#GO:0009566;reproductive process#GO:0022414;negative regulation of biological process#GO:0048519;single fertilization#GO:0007338;regulation of biological process#GO:0050789;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000025125.2|UniProtKB=G3SJZ2 G3SJZ2 LOC101144260 PTHR13042:SF3 UBIQUITIN-LIKE PROTEIN 5 UBIQUITIN-LIKE PROTEIN 5 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein metabolic process#GO:0019538;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;mRNA splicing, via spliceosome#GO:0000398;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000008710.3|UniProtKB=A0A2I2YIV4 A0A2I2YIV4 PTHR48018:SF14 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012613.3|UniProtKB=G3RA49 G3RA49 PCBP2 PTHR10288:SF97 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 2 RNA binding#GO:0003723;DNA binding#GO:0003677;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697 regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003980.3|UniProtKB=G3QN05 G3QN05 RPLP1 PTHR45696:SF32 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 kinase activator activity#GO:0019209;binding#GO:0005488;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;ribonucleoprotein complex binding#GO:0043021;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;structural constituent of ribosome#GO:0003735;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;structural molecule activity#GO:0005198;protein kinase regulator activity#GO:0019887 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010253.3|UniProtKB=Q0MQE0 Q0MQE0 NDUFB6 PTHR15083:SF0 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000024235.2|UniProtKB=G3SKA0 G3SKA0 PTHR24366:SF99 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 3 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000042156.1|UniProtKB=G3RVL4 G3RVL4 RPSA PTHR11489:SF17 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2-RELATED structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000036711.1|UniProtKB=G3RD28 G3RD28 AGO3 PTHR22891:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-3 nuclease activity#GO:0004518;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded RNA binding#GO:0003727;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000042905.1|UniProtKB=A0A2I2Z826 A0A2I2Z826 CHTF8 PTHR28605:SF3 CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE) CHROMOSOME TRANSMISSION FIDELITY PROTEIN 8 HOMOLOG regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of DNA metabolic process#GO:0051054;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000014033.3|UniProtKB=G3RZS6 G3RZS6 CACNA1H PTHR10037:SF192 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1H metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated sodium channel activity#GO:0005248;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;monoatomic cation transport#GO:0006812;regulation of secretion#GO:0051046;localization#GO:0051179;positive regulation of secretion#GO:0051047;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;action potential#GO:0001508;regulation of biological process#GO:0050789;calcium ion import#GO:0070509;regulation of localization#GO:0032879;regulation of transport#GO:0051049;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000015445.3|UniProtKB=G3RHE9 G3RHE9 LRRC56 PTHR22708:SF0 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56 GORGO|Ensembl=ENSGGOG00000009223.3|UniProtKB=G3R1F2 G3R1F2 LOC101124651 PTHR23120:SF5 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 9 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000038174.1|UniProtKB=A0A2I2YQN4 A0A2I2YQN4 PTHR21622:SF6 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 MITOCHONDRIAL INTERMEMBRANE SPACE IMPORT AND ASSEMBLY PROTEIN 40 protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;intracellular transport#GO:0046907;metabolic process#GO:0008152;biosynthetic process#GO:0009058;mitochondrial protein import pathway#GO:7770058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;protein metabolic process#GO:0019538;localization#GO:0051179;mitochondrial transport#GO:0006839;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000024324.2|UniProtKB=G3RXC8 G3RXC8 MYOZ1 PTHR15941:SF11 MYOZENIN MYOZENIN-1 molecular condensate scaffold activity#GO:0140693;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;muscle organ development#GO:0007517;cellular anatomical entity morphogenesis#GO:0032989;striated muscle tissue development#GO:0014706;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;striated muscle cell development#GO:0055002;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;tissue development#GO:0009888;skeletal muscle tissue development#GO:0007519;cellular developmental process#GO:0048869;system process#GO:0003008;developmental process#GO:0032502;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;muscle cell development#GO:0055001;cellular response to stimulus#GO:0051716;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029 sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;I band#GO:0031674;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000038347.1|UniProtKB=A0A2I2ZTX0 A0A2I2ZTX0 OR2J1 PTHR26453:SF184 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2J1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025226.2|UniProtKB=G3S888 G3S888 DPH2 PTHR10762:SF2 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000034981.2|UniProtKB=G3SKM3 G3SKM3 ABCA13 PTHR19229:SF113 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 13 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000026185.2|UniProtKB=G3S0C0 G3S0C0 ELMOD3 PTHR12771:SF2 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 3 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;cilium#GO:0005929;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004001.3|UniProtKB=A0A2I2YVV7 A0A2I2YVV7 ACTG2 PTHR11937:SF201 ACTIN ACTIN, GAMMA-ENTERIC SMOOTH MUSCLE structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intracellular organelle#GO:0043229;extracellular region#GO:0005576;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114 GORGO|Ensembl=ENSGGOG00000002592.3|UniProtKB=A0A2I2Y8V2 A0A2I2Y8V2 RHNO1 PTHR35541:SF1 RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 1 RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 1 cellular response to stress#GO:0033554;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;DNA integrity checkpoint signaling#GO:0031570;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000876.3|UniProtKB=G3QF03 G3QF03 NMBR PTHR45695:SF8 LEUCOKININ RECEPTOR-RELATED NEUROMEDIN-B RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026505.2|UniProtKB=G3RSB1 G3RSB1 POPDC1 PTHR12101:SF17 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 1 carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 cellular process#GO:0009987;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;heart development#GO:0007507;multicellular organismal process#GO:0032501;developmental process#GO:0032502;striated muscle cell differentiation#GO:0051146;multicellular organism development#GO:0007275;regulation of membrane potential#GO:0042391;animal organ development#GO:0048513;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856 anchoring junction#GO:0070161;sarcolemma#GO:0042383;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000008090.3|UniProtKB=A0A2I2ZIE9 A0A2I2ZIE9 FAM234B PTHR21419:SF25 FAMILY NOT NAMED PROTEIN FAM234B GORGO|Ensembl=ENSGGOG00000006123.3|UniProtKB=A0A2I2Y7P0 A0A2I2Y7P0 IFI16 PTHR12200:SF5 INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER GAMMA-INTERFERON-INDUCIBLE PROTEIN 16 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;positive regulation of response to external stimulus#GO:0032103;positive regulation of response to biotic stimulus#GO:0002833;activation of innate immune response#GO:0002218;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831 cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000024153.2|UniProtKB=A0A2I2Y9U3 A0A2I2Y9U3 PTHR10416:SF0 DNA POLYMERASE DELTA SUBUNIT 2 DNA POLYMERASE DELTA SUBUNIT 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;DNA biosynthetic process#GO:0071897;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;DNA synthesis involved in DNA replication#GO:0090592;DNA-templated DNA replication#GO:0006261;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 protein-DNA complex#GO:0032993;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;replisome#GO:0030894;replication fork#GO:0005657;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 GORGO|Ensembl=ENSGGOG00000016321.3|UniProtKB=G3RJM3 G3RJM3 NCKAP5L PTHR21740:SF3 NCK-ASSOCIATED PROTEIN 5 NCK-ASSOCIATED PROTEIN 5-LIKE supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular component disassembly#GO:0022411;microtubule bundle formation#GO:0001578;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component organization#GO:0016043 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;microtubule end#GO:1990752;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000011579.3|UniProtKB=G3R7F6 G3R7F6 ISCU PTHR10093:SF15 IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG IRON-SULFUR CLUSTER ASSEMBLY ENZYME ISCU ferrous iron binding#GO:0008198;iron ion binding#GO:0005506;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169 chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000027762.2|UniProtKB=A0A2I2YII7 A0A2I2YII7 PTHR48026:SF2 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000013460.3|UniProtKB=G3RCA2 G3RCA2 PELI1 PTHR12098:SF4 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000041935.1|UniProtKB=A0A2I2Y950 A0A2I2Y950 PTHR10902:SF36 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;translation#GO:0006412;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003837.3|UniProtKB=G3QMM6 G3QMM6 ZNF215 PTHR23226:SF65 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 215 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008347.3|UniProtKB=A0A2I2Z602 A0A2I2Z602 CDHR5 PTHR24028:SF243 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 5 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000000924.3|UniProtKB=A0A2I2Y4M3 A0A2I2Y4M3 NDUFA7 PTHR12485:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 7 cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;organelle membrane#GO:0031090;transporter complex#GO:1990351;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000026017.2|UniProtKB=G3SBK6 G3SBK6 LOC101130604 PTHR11375:SF15 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nuclear transport#GO:0051169;intracellular transport#GO:0046907;nucleocytoplasmic transport#GO:0006913;regulation of apoptotic process#GO:0042981;transport#GO:0006810;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;establishment of localization in cell#GO:0051649;regulation of biological process#GO:0050789;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000024973.2|UniProtKB=G3S418 G3S418 CDCA7 PTHR31169:SF2 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 7 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000000371.3|UniProtKB=A0A2I2YB87 A0A2I2YB87 EFNA5 PTHR11304:SF33 EPHRIN EPHRIN-A5 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cytoskeleton organization#GO:0051493;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;nervous system development#GO:0007399;regulation of actin cytoskeleton organization#GO:0032956;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000022296.2|UniProtKB=A0A2I2ZB61 A0A2I2ZB61 LOC101141672 PTHR15341:SF3 SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;RNA binding#GO:0003723 metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biosynthetic process#GO:0009058;biological regulation#GO:0065007;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000001214.3|UniProtKB=G3QFW4 G3QFW4 PNMA8A PTHR23095:SF21 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 8A transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000025130.2|UniProtKB=G3RPL5 G3RPL5 BPNT2 PTHR43028:SF6 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 GOLGI-RESIDENT ADENOSINE 3',5'-BISPHOSPHATE 3'-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 anatomical structure development#GO:0048856;skeletal system development#GO:0001501;cartilage development#GO:0051216;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;cell development#GO:0048468;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;connective tissue development#GO:0061448;developmental process#GO:0032502;tissue development#GO:0009888;chondrocyte differentiation#GO:0002062;multicellular organismal process#GO:0032501;cellular process#GO:0009987 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000039857.1|UniProtKB=G3S8L5 G3S8L5 PTHR18860:SF7 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA_DELTA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;PI3 kinase pathway#P00048>14-3-3#P01206;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624 GORGO|Ensembl=ENSGGOG00000014793.3|UniProtKB=G3RFR1 G3RFR1 SLC27A4 PTHR43107:SF11 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 4 monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;catalytic activity#GO:0003824;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;import into cell#GO:0098657 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000010772.3|UniProtKB=G3R5C8 G3R5C8 GJB1 PTHR11984:SF20 CONNEXIN GAP JUNCTION BETA-1 PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796 cell junction protein#PC00070;gap junction#PC00105 GORGO|Ensembl=ENSGGOG00000037826.1|UniProtKB=A0A2I2Y9I4 A0A2I2Y9I4 PTHR14217:SF22 INOSITOL-TETRAKISPHOSPHATE 1-KINASE INOSITOL-TETRAKISPHOSPHATE 1-KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002988.3|UniProtKB=G3QKJ8 G3QKJ8 SYNE2 PTHR14514:SF4 PKA ANCHORING PROTEIN NESPRIN-2 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle localization#GO:0051640;cellular localization#GO:0051641;localization#GO:0051179;regulation of cell projection assembly#GO:0060491;regulation of organelle organization#GO:0033043;nuclear migration#GO:0007097;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;centrosome localization#GO:0051642;intracellular transport#GO:0046907;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;transport#GO:0006810;establishment of localization#GO:0051234;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007 sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;organelle envelope#GO:0031967;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;sarcomere#GO:0030017;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;membrane#GO:0016020;nucleus#GO:0005634;sarcoplasmic reticulum#GO:0016529;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635 GORGO|Ensembl=ENSGGOG00000041851.1|UniProtKB=A0A2I2YFJ4 A0A2I2YFJ4 NKX3-1 PTHR24340:SF38 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000000113.3|UniProtKB=G3QD08 G3QD08 TMEM256 PTHR43461:SF1 TRANSMEMBRANE PROTEIN 256 TRANSMEMBRANE PROTEIN 256 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000036626.1|UniProtKB=G3QJ38 G3QJ38 LOC101154372 PTHR26453:SF607 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AG2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007842.3|UniProtKB=A0A2I2Z6H5 A0A2I2Z6H5 CYP2C18 PTHR24300:SF429 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C18 binding#GO:0005488;tetrapyrrole binding#GO:0046906;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 xenobiotic metabolic process#GO:0006805;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;olefinic compound metabolic process#GO:0120254;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000004273.3|UniProtKB=A0A2I2YGU3 A0A2I2YGU3 TRAF3 PTHR10131:SF76 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 3 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;signal transduction#GO:0007165;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001378.3|UniProtKB=G3QGA7 G3QGA7 GABRE PTHR18945:SF397 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT EPSILON transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;channel activity#GO:0015267;molecular transducer activity#GO:0060089 animal gross anatomical part developmental process#GO:0160108;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;signaling#GO:0023052;chloride transport#GO:0006821;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;nervous system development#GO:0007399;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;localization#GO:0051179;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;anatomical structure development#GO:0048856;system development#GO:0048731;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220 neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection membrane#GO:0031253;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000007783.3|UniProtKB=G3RTC1 G3RTC1 GABPB1 PTHR24193:SF76 ANKYRIN REPEAT PROTEIN GA-BINDING PROTEIN SUBUNIT BETA-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000016314.3|UniProtKB=A0A2I2ZV65 A0A2I2ZV65 KIF13A PTHR24115:SF458 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF13A cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544 intracellular protein localization#GO:0008104;protein transport#GO:0015031;microtubule-based process#GO:0007017;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;microtubule-based movement#GO:0007018;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000038256.1|UniProtKB=A0A2I2YVV9 A0A2I2YVV9 PTHR37932:SF1 SMALL LYSINE-RICH PROTEIN 1 SMALL LYSINE-RICH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000003158.4|UniProtKB=A0A2I2Z413 A0A2I2Z413 ARHGEF9 PTHR47544:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000023459.2|UniProtKB=G3SAT8 G3SAT8 RESF1 PTHR21604:SF0 RETROELEMENT SILENCING FACTOR 1 RETROELEMENT SILENCING FACTOR 1 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000000446.4|UniProtKB=G3QDV9 G3QDV9 HSPBAP1 PTHR12461:SF43 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HSPB1-ASSOCIATED PROTEIN 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015798.3|UniProtKB=A0A2I2Z9E3 A0A2I2Z9E3 ARMC3 PTHR46618:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 3 ARMADILLO REPEAT-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000000392.3|UniProtKB=G3QDR1 G3QDR1 SRSF10 PTHR23147:SF5 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 10 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000012930.3|UniProtKB=G3RTY2 G3RTY2 ERO1A PTHR12613:SF1 ERO1-RELATED ERO1-LIKE PROTEIN ALPHA oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 protein folding#GO:0006457;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;signal transduction#GO:0007165;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000004593.3|UniProtKB=A0A2I2ZKR7 A0A2I2ZKR7 TGFB2 PTHR11848:SF141 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-2 PROPROTEIN receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;response to transforming growth factor beta#GO:0071559;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>TGFbeta#P06778 GORGO|Ensembl=ENSGGOG00000003519.3|UniProtKB=G3QLU2 G3QLU2 WDR89 PTHR22889:SF0 WD REPEAT-CONTAINING PROTEIN 89 WD REPEAT-CONTAINING PROTEIN 89 GORGO|Ensembl=ENSGGOG00000003965.3|UniProtKB=G3QMZ0 G3QMZ0 KBTBD2 PTHR24412:SF192 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 2 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004093.3|UniProtKB=G3QNA6 G3QNA6 EIF2S3B PTHR42854:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER PROTEIN-SYNTHESIZING GTPASE translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;translation initiation factor activity#GO:0003743;tRNA binding#GO:0000049;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000000793.3|UniProtKB=G3QET1 G3QET1 SIPA1L2 PTHR15711:SF7 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 2 GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cell junction#GO:0030054;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000043595.1|UniProtKB=G3RY19 G3RY19 TLR4 PTHR24365:SF521 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 4 lipopolysaccharide binding#GO:0001530;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;lipid binding#GO:0008289;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;response to lipid#GO:0033993;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;signaling#GO:0023052;toll-like receptor signaling pathway#GO:0002224;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;detection of chemical stimulus#GO:0009593;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to oxygen-containing compound#GO:1901700;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;toll-like receptor 4 signaling pathway#GO:0034142;immune response-regulating cell surface receptor signaling pathway#GO:0002768;response to other organism#GO:0051707;activation of innate immune response#GO:0002218;detection of stimulus#GO:0051606;positive regulation of innate immune response#GO:0045089;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to bacterium#GO:0009617;inflammatory response#GO:0006954;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane protein complex#GO:0098796;membrane#GO:0016020 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR#P01346;Toll receptor signaling pathway#P00054>TLR4#P01339 GORGO|Ensembl=ENSGGOG00000025574.2|UniProtKB=A0A2I2YGB2 A0A2I2YGB2 PTHR43247:SF6 PHOSPHOSERINE AMINOTRANSFERASE PHOSPHOSERINE AMINOTRANSFERASE heterocyclic compound binding#GO:1901363;transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000012541.3|UniProtKB=G3S6P1 G3S6P1 ADAMTS13 PTHR13723:SF20 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 13 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000001521.4|UniProtKB=G3QGP6 G3QGP6 TMEM131 PTHR22050:SF1 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131 cellular process#GO:0009987;metabolic process#GO:0008152;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000006156.3|UniProtKB=G3QTJ7 G3QTJ7 GATA2 PTHR10071:SF149 TRANSCRIPTION FACTOR GATA FAMILY MEMBER ENDOTHELIAL TRANSCRIPTION FACTOR GATA-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;positive regulation of angiogenesis#GO:0045766;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of vasculature development#GO:1901342;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of angiogenesis#GO:0045765;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>GATA2/4#P06859 GORGO|Ensembl=ENSGGOG00000025551.2|UniProtKB=G3RSR9 G3RSR9 PTHR11205:SF38 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;RNA binding#GO:0003723 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014404.3|UniProtKB=G3REQ7 G3REQ7 TMSB10 PTHR12021:SF10 THYMOSIN BETA THYMOSIN BETA-10 protein binding#GO:0005515;molecular sequestering activity#GO:0140313;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein sequestering activity#GO:0140311;actin binding#GO:0003779;actin monomer binding#GO:0003785 regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell migration#GO:0030334;regulation of biological process#GO:0050789 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000002980.3|UniProtKB=G3QKF8 G3QKF8 CASTOR2 PTHR31131:SF2 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 2 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;cellular response to amino acid stimulus#GO:0071230;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;response to nitrogen compound#GO:1901698;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cellular response to oxygen-containing compound#GO:1901701;response to acid chemical#GO:0001101;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000022535.2|UniProtKB=G3RPW3 G3RPW3 PTHR10527:SF53 IMPORTIN BETA TRANSPORTIN-1 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008606.3|UniProtKB=G3QZU4 G3QZU4 DLK2 PTHR24044:SF423 NOTCH LIGAND FAMILY MEMBER PROTEIN DELTA HOMOLOG 2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000038088.1|UniProtKB=A0A2I2ZLY4 A0A2I2ZLY4 PTHR13596:SF6 SMALL EDRK-RICH FACTOR 1 SMALL EDRK-RICH FACTOR 2 GORGO|Ensembl=ENSGGOG00000023790.2|UniProtKB=G3RPS5 G3RPS5 SMIM33 PTHR37873:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 33 SMALL INTEGRAL MEMBRANE PROTEIN 33 GORGO|Ensembl=ENSGGOG00000040531.1|UniProtKB=A0A2I2YPB7 A0A2I2YPB7 LOC101123800 PTHR11353:SF194 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000014275.3|UniProtKB=G3SFX8 G3SFX8 RNPS1 PTHR15481:SF2 RIBONUCLEIC ACID BINDING PROTEIN S1 RNA-BINDING PROTEIN WITH SERINE-RICH DOMAIN 1 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000044086.1|UniProtKB=A0A2I2ZV93 A0A2I2ZV93 ZNF490 PTHR24377:SF1004 IP01015P-RELATED ZINC FINGER PROTEIN 490 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000041051.1|UniProtKB=G3R3I4 G3R3I4 NR2E1 PTHR24083:SF98 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1 transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000015981.3|UniProtKB=G3RIS2 G3RIS2 RAB5A PTHR24073:SF1129 DRAB5-RELATED RAS-RELATED PROTEIN RAB-5A hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;intracellular protein transport#GO:0006886;transport#GO:0006810;regulation of synaptic plasticity#GO:0048167;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;regulation of neuronal synaptic plasticity#GO:0048168;import into cell#GO:0098657;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708;endocytic vesicle#GO:0030139;early endosome#GO:0005769;exocytic vesicle#GO:0070382;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000011585.3|UniProtKB=G3S9E5 G3S9E5 CACNG2 PTHR12107:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;nervous system process#GO:0050877;localization within membrane#GO:0051668;positive regulation of synaptic transmission#GO:0050806;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;regulation of synaptic transmission, glutamatergic#GO:0051966;localization#GO:0051179;cell communication#GO:0007154 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cell junction#GO:0030054;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;transporter#PC00227;ion channel#PC00133 Ionotropic glutamate receptor pathway#P00037>stargazin#P00998 GORGO|Ensembl=ENSGGOG00000014713.3|UniProtKB=G3RFI7 G3RFI7 NPTX2 PTHR19277:SF1 PENTRAXIN NEURONAL PENTRAXIN-2 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012787.3|UniProtKB=G3RAK9 G3RAK9 GCKR PTHR10088:SF4 GLUCOKINASE REGULATORY PROTEIN GLUCOKINASE REGULATORY PROTEIN kinase inhibitor activity#GO:0019210;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;carbohydrate derivative binding#GO:0097367;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;carbohydrate homeostasis#GO:0033500;protein localization to organelle#GO:0033365;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;localization#GO:0051179;intracellular protein localization#GO:0008104;intracellular chemical homeostasis#GO:0055082;glucose homeostasis#GO:0042593;intracellular glucose homeostasis#GO:0001678;cellular homeostasis#GO:0019725 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000037703.1|UniProtKB=A0A2I2YZF0 A0A2I2YZF0 TIMM9 PTHR13172:SF2 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9 protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial envelope#GO:0005740;mitochondrial intermembrane space#GO:0005758 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000001775.3|UniProtKB=G3QHC6 G3QHC6 ATP10A PTHR24092:SF81 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VA transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303 macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007129.3|UniProtKB=G3QW31 G3QW31 PTHR10372:SF1 PLAKOPHILLIN-RELATED PLAKOPHILIN-3 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cell junction#GO:0030054;nucleus#GO:0005634;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 intermediate filament#PC00129;cytoskeletal protein#PC00085;intermediate filament binding protein#PC00130 GORGO|Ensembl=ENSGGOG00000026018.3|UniProtKB=G3SB70 G3SB70 CD163L1 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000010410.3|UniProtKB=G3R4G1 G3R4G1 BRD4 PTHR22880:SF143 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008302.3|UniProtKB=G3QYZ8 G3QYZ8 PTHR24028:SF302 CADHERIN-87A PROTOCADHERIN BETA-3 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000015776.3|UniProtKB=A0A2I2YF10 A0A2I2YF10 GTDC1 PTHR13615:SF3 GLYCOSYLTRANSFERASE-LIKE 1 TRNA-QUEUOSINE ALPHA-MANNOSYLTRANSFERASE glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000023023.2|UniProtKB=G3RXJ4 G3RXJ4 MS4A2 PTHR23320:SF66 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT BETA cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004345.3|UniProtKB=G3S2Y3 G3S2Y3 VAMP3 PTHR45701:SF6 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 3 binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 vesicle fusion#GO:0006906;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;localization#GO:0051179;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810 intracellular anatomical structure#GO:0005622;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 membrane traffic protein#PC00150 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423 GORGO|Ensembl=ENSGGOG00000013306.3|UniProtKB=G3RT21 G3RT21 MPP7 PTHR23122:SF39 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 7 macromolecule localization#GO:0033036;protein localization to cell junction#GO:1902414;localization#GO:0051179;intracellular protein localization#GO:0008104 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006284.3|UniProtKB=G3QTW9 G3QTW9 ARHGEF25 PTHR22826:SF117 RHO GUANINE EXCHANGE FACTOR-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 25 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extrinsic component of membrane#GO:0019898;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000036265.1|UniProtKB=G3RG03 G3RG03 PTHR23262:SF134 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-11 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000005988.3|UniProtKB=A0A2I2ZXV9 A0A2I2ZXV9 ANKRD42 PTHR24201:SF2 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 42 protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;transcription factor binding#GO:0008134 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000009100.3|UniProtKB=G3R144 G3R144 CXCR2 PTHR10489:SF689 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 2 cytokine receptor activity#GO:0004896;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089 chemotaxis#GO:0006935;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;locomotion#GO:0040011;leukocyte migration#GO:0050900;leukocyte chemotaxis#GO:0030595;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;immune response#GO:0006955;cell migration#GO:0016477;biological regulation#GO:0065007;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;signaling#GO:0023052;neutrophil chemotaxis#GO:0030593;cellular process#GO:0009987;signal transduction#GO:0007165;granulocyte migration#GO:0097530;response to chemical#GO:0042221;neutrophil migration#GO:1990266;taxis#GO:0042330;intracellular signaling cassette#GO:0141124 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000004969.3|UniProtKB=G3RPP3 G3RPP3 IKZF1 PTHR24404:SF36 ZINC FINGER PROTEIN DNA-BINDING PROTEIN IKAROS sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000006613.3|UniProtKB=G3QUR2 G3QUR2 SF3A2 PTHR23205:SF0 SPLICING FACTOR 3A SUBUNIT 2 SPLICING FACTOR 3A SUBUNIT 2 spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607 spliceosomal complex#GO:0005681;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036645.1|UniProtKB=A0A2I2ZBR7 A0A2I2ZBR7 MTHFD2 PTHR48099:SF15 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;oxidoreductase activity#GO:0016491;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 GORGO|Ensembl=ENSGGOG00000026334.2|UniProtKB=A0A2I2ZGU7 A0A2I2ZGU7 C17H18orf21 PTHR31402:SF2 UPF0711 PROTEIN C18ORF21 RIBONUCLEASE MRP PROTEIN SUBUNIT P24 GORGO|Ensembl=ENSGGOG00000000090.3|UniProtKB=G3QCY6 G3QCY6 SCLY PTHR11601:SF62 CYSTEINE DESULFURYLASE FAMILY MEMBER SELENOCYSTEINE LYASE metabolite interconversion enzyme#PC00262;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000002365.3|UniProtKB=G3QIV7 G3QIV7 SCAND3 PTHR45935:SF15 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN 3 GORGO|Gene=TAS1R2|UniProtKB=A3QNZ9 A3QNZ9 TAS1R2 PTHR14516:SF8 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER TASTE RECEPTOR TYPE 1 MEMBER 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000022912.2|UniProtKB=G3RQ74 G3RQ74 CHM PTHR11787:SF12 RAB GDP-DISSOCIATION INHIBITOR RAB PROTEINS GERANYLGERANYLTRANSFERASE COMPONENT A 1 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;vesicle-mediated transport#GO:0016192;protein targeting#GO:0006605;transport#GO:0006810;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000022026.2|UniProtKB=G3S9Z1 G3S9Z1 CCDC197 PTHR21683:SF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED COILED-COIL DOMAIN CONTAINING 197 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000003217.3|UniProtKB=G3QL22 G3QL22 LOC101153230 PTHR24291:SF27 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F12 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;icosanoid metabolic process#GO:0006690;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;vitamin K metabolic process#GO:0042373;primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;arachidonate metabolic process#GO:0019369 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000002494.3|UniProtKB=G3SGL7 G3SGL7 CDK16 PTHR24056:SF174 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 16 cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cell development#GO:0048468;export from cell#GO:0140352;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular component organization#GO:0016043;neuron development#GO:0048666;secretion by cell#GO:0032940;system development#GO:0048731;secretion#GO:0046903;anatomical structure development#GO:0048856;localization#GO:0051179;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;neuron projection development#GO:0031175;neurogenesis#GO:0022008;exocytosis#GO:0006887;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;neuron differentiation#GO:0030182;developmental process#GO:0032502 transferase complex, transferring phosphorus-containing groups#GO:0061695;exocytic vesicle#GO:0070382;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;cell junction#GO:0030054;protein kinase complex#GO:1902911;secretory vesicle#GO:0099503;nucleus#GO:0005634;presynapse#GO:0098793;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle#GO:0030133;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000001321.3|UniProtKB=G3QG54 G3QG54 TBC1D22B PTHR22957:SF462 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 22B nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000016311.3|UniProtKB=G3SAS8 G3SAS8 ZNF732 PTHR24393:SF187 ZINC FINGER PROTEIN ZINC FINGER PROTEIN sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000016370.3|UniProtKB=G3S035 G3S035 MED26 PTHR15201:SF1 CRSP70 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000040695.1|UniProtKB=A0A2I2YGD7 A0A2I2YGD7 PTHR11581:SF19 30S/40S RIBOSOMAL PROTEIN S4 40S RIBOSOMAL PROTEIN S4 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004751.3|UniProtKB=G3QPZ4 G3QPZ4 ERH PTHR12373:SF9 ENHANCER OF RUDIMENTARY ERH ENHANCER OF RUDIMENTARY HOMOLOG molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 regulation of chromatin organization#GO:1902275;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nuclear mRNA surveillance#GO:0071028;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000036779.1|UniProtKB=A0A2I2YSK2 A0A2I2YSK2 MOB4 PTHR22599:SF56 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB-LIKE PROTEIN PHOCEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000011292.3|UniProtKB=A0A2I2ZAL4 A0A2I2ZAL4 FOLR2 PTHR10517:SF8 FOLATE RECEPTOR FOLATE RECEPTOR BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cargo receptor activity#GO:0038024 vitamin transport#GO:0051180;dicarboxylic acid transport#GO:0006835;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000014838.3|UniProtKB=G3S5Y9 G3S5Y9 TMEM266 PTHR46842:SF1 TRANSMEMBRANE PROTEIN 266 TRANSMEMBRANE PROTEIN 266 GORGO|Ensembl=ENSGGOG00000024302.2|UniProtKB=A0A2I2Z941 A0A2I2Z941 PTHR11363:SF4 60S RIBOSOMAL PROTEIN L3-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL3 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004147.3|UniProtKB=G3QNF5 G3QNF5 RBPJL PTHR10665:SF2 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS-LIKE PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Notch signaling pathway#P00045>Su(H)#P01101;Angiogenesis#P00005>CSL#P00233 GORGO|Ensembl=ENSGGOG00000023519.2|UniProtKB=G3S1L2 G3S1L2 CCDC159 PTHR34533:SF1 TRANSMEMBRANE PROTEIN CCDC163 COILED-COIL DOMAIN-CONTAINING PROTEIN 159 GORGO|Ensembl=ENSGGOG00000040012.1|UniProtKB=G3QQL2 G3QQL2 LCAT PTHR11440:SF18 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED PHOSPHATIDYLCHOLINE-STEROL ACYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000002751.3|UniProtKB=G3QJV8 G3QJV8 CNPY4 PTHR15382:SF3 CTG4A-RELATED PROTEIN CANOPY HOMOLOG 4 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 GORGO|Ensembl=ENSGGOG00000003357.3|UniProtKB=G3QLF2 G3QLF2 SCNM1 PTHR32297:SF1 SODIUM CHANNEL MODIFIER 1 SODIUM CHANNEL MODIFIER 1 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000005734.3|UniProtKB=G3QSI8 G3QSI8 MCF2L2 PTHR22826:SF201 RHO GUANINE EXCHANGE FACTOR-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR MCF2L2-RELATED guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000001349.3|UniProtKB=G3QG78 G3QG78 XKRX PTHR14297:SF4 MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER XK-RELATED PROTEIN 2 GORGO|Ensembl=ENSGGOG00000012227.3|UniProtKB=A0A2I2ZYM0 A0A2I2ZYM0 PFKFB2 PTHR10606:SF48 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 2 sugar-phosphatase activity#GO:0050308;hydrolase activity#GO:0016787;phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;kinase activity#GO:0016301;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphoric ester hydrolase activity#GO:0042578 phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 carbohydrate phosphatase#PC00066;hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000000291.3|UniProtKB=G3QDG9 G3QDG9 SLAMF1 PTHR12080:SF49 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;immune response#GO:0006955;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;immune system process#GO:0002376 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000009990.3|UniProtKB=A0A2I2ZE35 A0A2I2ZE35 ATL2 PTHR10751:SF42 GUANYLATE BINDING PROTEIN ATLASTIN-2 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 heterotrimeric G-protein#PC00117;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000039729.1|UniProtKB=A0A2I2ZEX2 A0A2I2ZEX2 TGFBR3L PTHR14002:SF9 ENDOGLIN/TGF-BETA RECEPTOR TYPE III TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE 3-LIKE PROTEIN transforming growth factor beta receptor activity#GO:0005024;kinase activity#GO:0016301;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transforming growth factor beta binding#GO:0050431;transmembrane receptor protein kinase activity#GO:0019199;cytokine binding#GO:0019955;catalytic activity, acting on a protein#GO:0140096;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102;molecular transducer activity#GO:0060089 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;mesenchyme development#GO:0060485;tissue development#GO:0009888;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;response to transforming growth factor beta#GO:0071559;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway#GO:0007166;mesenchymal cell differentiation#GO:0048762;animal organ development#GO:0048513;transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016832.3|UniProtKB=G3RKY9 G3RKY9 OOEP PTHR19447:SF14 OOCYTE-EXPRESSED PROTEIN HOMOLOG-RELATED OOCYTE-EXPRESSED PROTEIN HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular process#GO:0009987;embryonic pattern specification#GO:0009880;embryo development#GO:0009790;multicellular organismal process#GO:0032501;developmental process#GO:0032502;pattern specification process#GO:0007389;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856 GORGO|Ensembl=ENSGGOG00000022733.2|UniProtKB=A0A2I2Y9A8 A0A2I2Y9A8 EPB41L1 PTHR23280:SF24 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 1 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Nicotine pharmacodynamics pathway#P06587>EPB41L1#P06599;Dopamine receptor mediated signaling pathway#P05912>EPB41L1#P05953;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 GORGO|Ensembl=ENSGGOG00000022673.2|UniProtKB=G3SBG9 G3SBG9 LOC109023188 PTHR11905:SF231 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPEPTIDASE DOMAIN 21 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000004823.3|UniProtKB=G3QQ67 G3QQ67 CSRP3 PTHR24215:SF1 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 3 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198 membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;heart process#GO:0003015;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;striated muscle contraction#GO:0006941;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system process#GO:0003013;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;tissue development#GO:0009888;muscle contraction#GO:0006936;developmental process#GO:0032502;cellular developmental process#GO:0048869;system process#GO:0003008;heart contraction#GO:0060047 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;nucleus#GO:0005634;sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000001960.3|UniProtKB=G3QHU4 G3QHU4 NFATC2IP PTHR47187:SF1 NFATC2-INTERACTING PROTEIN NFATC2-INTERACTING PROTEIN positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 GORGO|Ensembl=ENSGGOG00000000368.3|UniProtKB=G3QDN7 G3QDN7 NLE1 PTHR19848:SF10 WD40 REPEAT PROTEIN NOTCHLESS PROTEIN HOMOLOG 1 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000025861.2|UniProtKB=G3SEG4 G3SEG4 AKAP5 PTHR15182:SF0 A-KINASE ANCHOR PROTEIN 5-RELATED A-KINASE ANCHOR PROTEIN 5 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase A regulatory subunit binding#GO:0034237;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;GABA receptor binding#GO:0050811;protein kinase A binding#GO:0051018 postsynapse#GO:0098794;dendritic spine#GO:0043197;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cell projection#GO:0042995;dendrite#GO:0030425;postsynaptic density#GO:0014069;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;cell projection membrane#GO:0031253;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;neuron projection membrane#GO:0032589;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015308.3|UniProtKB=G3RH13 G3RH13 INHBB PTHR11848:SF29 TGF-BETA FAMILY INHIBIN BETA B CHAIN signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inhba/b#P06700;TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000011453.3|UniProtKB=G3R743 G3R743 TEX2 PTHR13466:SF2 TEX2 PROTEIN-RELATED TESTIS-EXPRESSED PROTEIN 2 binding#GO:0005488;lipid binding#GO:0008289 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000010593.3|UniProtKB=G3R4W4 G3R4W4 SPMAP2 PTHR15901:SF16 TESTICULAR HAPLOID EXPRESSED GENE PROTEIN SPERM MICROTUBULE ASSOCIATED PROTEIN 2 developmental process involved in reproduction#GO:0003006;gamete generation#GO:0007276;male gamete generation#GO:0048232;reproductive process#GO:0022414;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;multicellular organismal reproductive process#GO:0048609 GORGO|Ensembl=ENSGGOG00000005120.3|UniProtKB=G3SC50 G3SC50 PLEKHA1 PTHR14336:SF4 TANDEM PH DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 1 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000010229.3|UniProtKB=A0A2I2Z3B6 A0A2I2Z3B6 IL4I1 PTHR10742:SF21 FLAVIN MONOAMINE OXIDASE L-AMINO-ACID OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056 oxidase#PC00175 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 GORGO|Ensembl=ENSGGOG00000044125.1|UniProtKB=A0A2I2YM42 A0A2I2YM42 MTX2 PTHR12289:SF38 METAXIN RELATED METAXIN-2 protein insertion into membrane#GO:0051205;cellular component assembly#GO:0022607;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040 cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003916.3|UniProtKB=G3SFI8 G3SFI8 MTX3 PTHR12289:SF30 METAXIN RELATED METAXIN-3 cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003;cellular localization#GO:0051641;localization#GO:0051179;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668 membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004254.3|UniProtKB=G3QNQ7 G3QNQ7 RPS6KA5 PTHR24351:SF115 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-5 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of nucleobase-containing compound metabolic process#GO:0019219;TOR signaling#GO:0031929;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;TORC1 signaling#GO:0038202;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;signaling#GO:0023052 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;p38 MAPK pathway#P05918>MSK1#P06040;PDGF signaling pathway#P00047>p90RSK#P01142 GORGO|Ensembl=ENSGGOG00000003032.3|UniProtKB=G3QKL2 G3QKL2 MGAT5 PTHR15075:SF5 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001012.3|UniProtKB=G3SD01 G3SD01 ADAM7 PTHR11905:SF21 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 7 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000011052.3|UniProtKB=G3R632 G3R632 RBM18 PTHR21245:SF2 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 18-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003030.3|UniProtKB=G3QKK5 G3QKK5 ESR2 PTHR48092:SF12 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN RECEPTOR BETA signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089 cellular response to steroid hormone stimulus#GO:0071383;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;estrogen receptor signaling pathway#GO:0030520;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;response to steroid hormone#GO:0048545;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000036478.1|UniProtKB=A0A2I2ZXT7 A0A2I2ZXT7 GABRG3 PTHR18945:SF195 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-3 neurotransmitter receptor activity#GO:0030594;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 cellular process#GO:0009987;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;chloride transport#GO:0006821;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;signaling#GO:0023052;synapse assembly#GO:0007416;animal gross anatomical part developmental process#GO:0160108;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;anatomical structure development#GO:0048856;chloride transmembrane transport#GO:1902476;localization#GO:0051179;cell communication#GO:0007154 cell projection membrane#GO:0031253;dendrite#GO:0030425;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000011864.3|UniProtKB=G3RP05 G3RP05 LOC101136823 PTHR43880:SF57 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE 1C catalytic activity#GO:0003824;zinc ion binding#GO:0008270;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;binding#GO:0005488;small molecule binding#GO:0036094;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;cation binding#GO:0043169 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cellular response to oxygen-containing compound#GO:1901701;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;olefinic compound metabolic process#GO:0120254;regulation of biological quality#GO:0065008;regulation of hormone levels#GO:0010817;cellular detoxification of aldehyde#GO:0110095;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;biological regulation#GO:0065007;aldehyde catabolic process#GO:0046185;hormone metabolic process#GO:0042445;terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;isoprenoid metabolic process#GO:0006720;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to toxic substance#GO:0009636 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000026731.2|UniProtKB=A0A2I2ZD86 A0A2I2ZD86 JOSD2 PTHR13291:SF2 JOSEPHIN 1, 2 JOSEPHIN-2 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 cysteine protease#PC00081;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008791.3|UniProtKB=A0A2I2Z9P1 A0A2I2Z9P1 DOCK8 PTHR23317:SF74 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 8 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;regulation of establishment or maintenance of cell polarity#GO:0032878;positive regulation of biological process#GO:0048518;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of lymphocyte activation#GO:0051249;regulation of Rho protein signal transduction#GO:0035023;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;positive regulation of cell motility#GO:2000147;regulation of leukocyte activation#GO:0002694;positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cell activation#GO:0050867;regulation of locomotion#GO:0040012;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;regulation of cell motility#GO:2000145;positive regulation of lymphocyte activation#GO:0051251;regulation of lymphocyte migration#GO:2000401;regulation of cell communication#GO:0010646;regulation of leukocyte migration#GO:0002685;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785 cellular anatomical structure#GO:0110165;cell leading edge#GO:0031252 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000043906.1|UniProtKB=A0A2I2YKK2 A0A2I2YKK2 PTHR48002:SF123 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4B1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000024762.2|UniProtKB=G3S043 G3S043 PRH1 PTHR23203:SF19 PROLINE-RICH PROTEIN SALIVARY ACIDIC PROLINE-RICH PHOSPHOPROTEIN 1_2 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000000173.3|UniProtKB=A0A2I2Z3L0 A0A2I2Z3L0 RRP1 PTHR13026:SF1 NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52 RIBOSOMAL RNA PROCESSING PROTEIN 1 HOMOLOG A transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000006462.3|UniProtKB=G3QUC0 G3QUC0 RNF180 PTHR46717:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF180 E3 UBIQUITIN-PROTEIN LIGASE RNF180 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;acyltransferase activity#GO:0016746;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 positive regulation of protein metabolic process#GO:0051247;positive regulation of protein catabolic process#GO:0045732;serotonin metabolic process#GO:0042428;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catecholamine metabolic process#GO:0006584;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of biological process#GO:0050789;phenol-containing compound metabolic process#GO:0018958;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;indole-containing compound metabolic process#GO:0042430;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;amine metabolic process#GO:0009308;regulation of protein metabolic process#GO:0051246;biogenic amine metabolic process#GO:0006576;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000026523.2|UniProtKB=G3RZ89 G3RZ89 PTHR31131:SF12 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE PROTEIN CASTOR3P-RELATED response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;cellular response to amino acid stimulus#GO:0071230;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;response to nitrogen compound#GO:1901698;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003343.3|UniProtKB=G3RSC7 G3RSC7 SYCE1 PTHR21731:SF0 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1-LIKE SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;synaptonemal structure#GO:0099086;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793 GORGO|Ensembl=ENSGGOG00000007259.4|UniProtKB=A0A2I2Y7N7 A0A2I2Y7N7 IFT74 PTHR31432:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;intraciliary transport involved in cilium assembly#GO:0035735;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271 membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intraciliary transport particle B#GO:0030992;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000016152.3|UniProtKB=G3RJ84 G3RJ84 PSIP1 PTHR12550:SF42 HEPATOMA-DERIVED GROWTH FACTOR-RELATED PC4 AND SFRS1-INTERACTING PROTEIN chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000005091.3|UniProtKB=G3QQW4 G3QQW4 LOC101132254 PTHR26452:SF262 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AN1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010398.3|UniProtKB=G3R4E5 G3R4E5 NCLN PTHR31826:SF8 NICALIN BOS COMPLEX SUBUNIT NCLN regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003874.3|UniProtKB=G3QMQ6 G3QMQ6 SCML1 PTHR12247:SF128 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000009549.3|UniProtKB=G3R283 G3R283 ZNF691 PTHR24393:SF122 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 691 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000012788.3|UniProtKB=A0A2I2YM15 A0A2I2YM15 SEC22C PTHR46258:SF2 LONGIN DOMAIN-CONTAINING PROTEIN VESICLE-TRAFFICKING PROTEIN SEC22C transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 GORGO|Ensembl=ENSGGOG00000034978.2|UniProtKB=G3SKM0 G3SKM0 CADPS2 PTHR12166:SF7 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR 2 regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;positive regulation of secretion#GO:0051047;export from cell#GO:0140352;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049;exocytosis#GO:0006887;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532 cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cell junction#GO:0030054 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000039697.1|UniProtKB=A0A2I2YZ95 A0A2I2YZ95 PTHR44813:SF1 MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1 MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000008435.3|UniProtKB=G3QZD3 G3QZD3 LRRC3 PTHR24369:SF170 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000002088.3|UniProtKB=G3QI54 G3QI54 ZNF512B PTHR22979:SF3 ZINC FINGER PROTEIN-RELATED ZINC FINGER PROTEIN 512B GORGO|Ensembl=ENSGGOG00000011945.3|UniProtKB=A0A2I2YKP2 A0A2I2YKP2 FAM219A PTHR31281:SF0 PROTEIN FAM219A PROTEIN FAM219A GORGO|Ensembl=ENSGGOG00000007312.3|UniProtKB=G3QWJ6 G3QWJ6 CHP1 PTHR46002:SF1 EG:114D9.1 PROTEIN-RELATED CALCINEURIN B HOMOLOGOUS PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;regulation of calcineurin-NFAT signaling cascade#GO:0070884 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000012672.3|UniProtKB=G3RAA0 G3RAA0 SEC14L2 PTHR23324:SF90 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 2 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000023611.2|UniProtKB=G3S4A2 G3S4A2 EPS8 PTHR12287:SF21 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8 protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;positive regulation of cell projection organization#GO:0031346;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of intracellular signal transduction#GO:1902531;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;response to stimulus#GO:0050896;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165 ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;ruffle#GO:0001726;cell projection membrane#GO:0031253;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026046.2|UniProtKB=G3R9Q0 G3R9Q0 PTHR12538:SF15 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000007998.3|UniProtKB=G3QY99 G3QY99 KEL PTHR11733:SF128 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED KELL BLOOD GROUP GLYCOPROTEIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;cellular process#GO:0009987;peptide hormone processing#GO:0016486;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;protein maturation#GO:0051604;hormone metabolic process#GO:0042445;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000001164.3|UniProtKB=G3QFR7 G3QFR7 NEIL2 PTHR22993:SF29 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;endonuclease activity#GO:0004519;DNA N-glycosylase activity#GO:0019104;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA glycosylase#PC00010 GORGO|Ensembl=ENSGGOG00000001628.3|UniProtKB=G3QGY7 G3QGY7 HOXC6 PTHR45659:SF1 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-C6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000012531.3|UniProtKB=G3R9X3 G3R9X3 ST8SIA2 PTHR11987:SF30 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8B sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000015619.3|UniProtKB=G3RHV9 G3RHV9 CDKL2 PTHR24056:SF241 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000042287.1|UniProtKB=A0A2I2YBR1 A0A2I2YBR1 FAM156A PTHR31577:SF3 DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 3-RELATED PROTEIN FAM156A_FAM156B nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000041309.1|UniProtKB=A0A2I2ZTD2 A0A2I2ZTD2 LOC101140783 PTHR46551:SF3 SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000016680.3|UniProtKB=G3RKK8 G3RKK8 ANXA5 PTHR10502:SF26 ANNEXIN ANNEXIN A5 phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;phospholipid binding#GO:0005543;anion binding#GO:0043168;ion binding#GO:0043167 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506 calcium-binding protein#PC00060 Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06684;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06897;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#P06814 GORGO|Ensembl=ENSGGOG00000001161.3|UniProtKB=A0A2I2Y6M9 A0A2I2Y6M9 DBNDD1 PTHR16294:SF4 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 GORGO|Ensembl=ENSGGOG00000008401.3|UniProtKB=A0A2I2YKE3 A0A2I2YKE3 APAF1 PTHR22845:SF5 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 FAS signaling pathway#P00020>Apaf1#P00597;Apoptosis signaling pathway#P00006>Apaf-1#P00301;Huntington disease#P00029>Apaf-1#P00768;p53 pathway#P00059>Apaf#G04703 GORGO|Ensembl=ENSGGOG00000011798.3|UniProtKB=G3R804 G3R804 SIRPD PTHR19971:SF25 SIGNAL-REGULATORY PROTEIN BETA SIGNAL-REGULATORY PROTEIN DELTA cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015471.3|UniProtKB=A0A2I2YN96 A0A2I2YN96 PIK3C3 PTHR10048:SF7 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 macroautophagy#GO:0016236;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;establishment of localization#GO:0051234;pexophagy#GO:0000425;lipid metabolic process#GO:0006629;transport#GO:0006810;glycerophospholipid biosynthetic process#GO:0046474;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;vacuole organization#GO:0007033;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;localization#GO:0051179;organelle assembly#GO:0070925;glycerophospholipid metabolic process#GO:0006650;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;signal transduction#GO:0007165;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;signaling#GO:0023052;endocytosis#GO:0006897;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;process utilizing autophagic mechanism#GO:0061919;phosphatidylinositol phosphate biosynthetic process#GO:0046854 microbody#GO:0042579;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;extrinsic component of membrane#GO:0019898;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;phosphatidylinositol 3-kinase complex, class III#GO:0035032;endosome#GO:0005768;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137 p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Angiogenesis#P00005>PI3K#P00236;PDGF signaling pathway#P00047>PI3K#P01168;Ras Pathway#P04393>PI3K#P04567;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;EGF receptor signaling pathway#P00018>PI3K#P00557;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;T cell activation#P00053>PI3K#P01322;VEGF signaling pathway#P00056>PI3K#P01413;Integrin signalling pathway#P00034>PI3K#P00936 GORGO|Ensembl=ENSGGOG00000022442.2|UniProtKB=G3S7Q3 G3S7Q3 AADACL3 PTHR23024:SF115 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE-LIKE 3 cellular anatomical structure#GO:0110165;membrane#GO:0016020 deacetylase#PC00087 GORGO|Ensembl=ENSGGOG00000022012.2|UniProtKB=A0A2I2Y614 A0A2I2Y614 PTHR23147:SF132 SERINE/ARGININE RICH SPLICING FACTOR RRM DOMAIN-CONTAINING PROTEIN supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000005687.3|UniProtKB=G3RVJ3 G3RVJ3 PFKL PTHR13697:SF14 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, LIVER TYPE transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate derivative binding#GO:0097367;carbohydrate kinase activity#GO:0019200;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphotransferase activity, alcohol group as acceptor#GO:0016773 small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 transferase#PC00220;carbohydrate kinase#PC00065;kinase#PC00137 Glycolysis#P00024>Phosphofructokinase-1#P00672 GORGO|Ensembl=ENSGGOG00000014324.3|UniProtKB=G3REH8 G3REH8 NUDT4 PTHR12629:SF6 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;alcohol metabolic process#GO:0006066;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000005839.3|UniProtKB=G3RP97 G3RP97 MUCL3 PTHR22094:SF0 DIFFUSE PANBRONCHIOLITIS CRITICAL REGION GENE 1 MUCIN-LIKE PROTEIN 3 GORGO|Ensembl=ENSGGOG00000022145.2|UniProtKB=A0A2I2Y416 A0A2I2Y416 PTHR10681:SF111 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-1 catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;cellular process#GO:0009987;response to stress#GO:0006950;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;superoxide metabolic process#GO:0006801;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000023640.2|UniProtKB=G3S3Y3 G3S3Y3 KDF1 PTHR35085:SF1 KERATINOCYTE DIFFERENTIATION FACTOR 1 KERATINOCYTE DIFFERENTIATION FACTOR 1 regulation of biological process#GO:0050789;regulation of cell division#GO:0051302;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000041585.1|UniProtKB=G3RIC5 G3RIC5 LOC101143138 PTHR12021:SF11 THYMOSIN BETA THYMOSIN BETA-15A-RELATED protein binding#GO:0005515;actin monomer binding#GO:0003785;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein sequestering activity#GO:0140311;binding#GO:0005488;molecular sequestering activity#GO:0140313 regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334 intracellular organelle#GO:0043229;actin filament#GO:0005884;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000026796.2|UniProtKB=G3RUE5 G3RUE5 LOC101133386 PTHR16716:SF1 CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 7B2, MITOCHONDRIAL respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transporter complex#GO:1990351;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277 oxidase#PC00175;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000023537.2|UniProtKB=Q0MQD1 Q0MQD1 NDUFB3 PTHR15082:SF2 NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3 electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060 membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000004882.3|UniProtKB=G3QQC0 G3QQC0 NEURL1B PTHR12429:SF10 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL1B acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of protein localization to organelle#GO:0072594;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;transport#GO:0006810;regulation of response to stimulus#GO:0048583;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;localization#GO:0051179;protein transport#GO:0015031;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002775.3|UniProtKB=G3QJX3 G3QJX3 IL1RAPL2 PTHR11890:SF10 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER X-LINKED INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 2 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011494.3|UniProtKB=A0A2I2Z9Q8 A0A2I2Z9Q8 PTPRQ PTHR46957:SF1 CYTOKINE RECEPTOR PHOSPHATIDYLINOSITOL PHOSPHATASE PTPRQ response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to mechanical stimulus#GO:0009612;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;sensory perception of sound#GO:0007605;detection of mechanical stimulus#GO:0050982;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;system process#GO:0003008;response to external stimulus#GO:0009605 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000017065.3|UniProtKB=G3RQ03 G3RQ03 FAT3 PTHR24025:SF21 DESMOGLEIN FAMILY MEMBER FAT ATYPICAL CADHERIN 3B calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000022142.2|UniProtKB=A0A2I2ZVX4 A0A2I2ZVX4 PTHR11849:SF279 ETS ETS DOMAIN-CONTAINING PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000001850.3|UniProtKB=A0A2I2YQ35 A0A2I2YQ35 TULP1 PTHR16517:SF12 TUBBY-RELATED TUBBY-RELATED PROTEIN 1 binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009490.3|UniProtKB=G3R234 G3R234 GRAMD1C PTHR23319:SF1 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-C small molecule binding#GO:0036094;binding#GO:0005488;molecular carrier activity#GO:0140104;sterol binding#GO:0032934;lipid carrier activity#GO:0005319;cholesterol binding#GO:0015485;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;sterol transfer activity#GO:0120015;transporter activity#GO:0005215;alcohol binding#GO:0043178;cholesterol transfer activity#GO:0120020;steroid binding#GO:0005496 organic hydroxy compound transport#GO:0015850;localization#GO:0051179;sterol transport#GO:0015918;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;intracellular transport#GO:0046907;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle membrane contact site#GO:0044232;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 GORGO|Ensembl=ENSGGOG00000015192.3|UniProtKB=A0A2I2YC11 A0A2I2YC11 CMA1 PTHR24271:SF24 KALLIKREIN-RELATED CHYMASE serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000016642.3|UniProtKB=G3RU31 G3RU31 PIH1D1 PTHR22997:SF0 PIH1 DOMAIN-CONTAINING PROTEIN 1 PIH1 DOMAIN-CONTAINING PROTEIN 1 RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 GORGO|Ensembl=ENSGGOG00000024242.2|UniProtKB=G3RQB9 G3RQB9 UBE2QL1 PTHR24068:SF72 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2Q-LIKE PROTEIN 1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000970.3|UniProtKB=G3QF89 G3QF89 PLAAT5 PTHR13943:SF2 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 5 catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;transferase activity#GO:0016740;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000026471.2|UniProtKB=G3SFI1 G3SFI1 TRIL PTHR45617:SF20 LEUCINE RICH REPEAT FAMILY PROTEIN TLR4 INTERACTOR WITH LEUCINE RICH REPEATS scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007506.3|UniProtKB=G3QX18 G3QX18 B4GALT3 PTHR19300:SF33 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 3 galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000005817.3|UniProtKB=A0A2I2YZM2 A0A2I2YZM2 CALU PTHR10827:SF76 RETICULOCALBIN CALUMENIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000040546.1|UniProtKB=A0A2I2ZKZ5 A0A2I2ZKZ5 PTHR47029:SF2 FOUR AND A HALF LIM DOMAINS PROTEIN 1 FOUR AND A HALF LIM DOMAINS PROTEIN 1 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 GORGO|Ensembl=ENSGGOG00000009440.3|UniProtKB=G3R1Z0 G3R1Z0 GPATCH2 PTHR14195:SF4 G PATCH DOMAIN CONTAINING PROTEIN 2 G PATCH DOMAIN-CONTAINING PROTEIN 2 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036592.1|UniProtKB=G3RWM3 G3RWM3 PTHR10709:SF11 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1A organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cortical actin cytoskeleton organization#GO:0030866;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 GORGO|Ensembl=ENSGGOG00000015731.3|UniProtKB=G3RI61 G3RI61 C7H8orf34 PTHR32000:SF3 SIMILAR TO HYPOTHETICAL PROTEIN SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 34 GORGO|Ensembl=ENSGGOG00000014835.3|UniProtKB=G3S173 G3S173 AGPAT5 PTHR10983:SF73 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE EPSILON acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004508.3|UniProtKB=G3QPC4 G3QPC4 PTHR14096:SF7 APOLIPOPROTEIN L APOLIPOPROTEIN L6 lipid binding#GO:0008289;binding#GO:0005488 membrane#GO:0016020;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000006765.3|UniProtKB=G3SDP9 G3SDP9 DVL2 PTHR10878:SF8 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-2 frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447;Alzheimer disease-presenilin pathway#P00004>Dsh#P00132 GORGO|Ensembl=ENSGGOG00000016879.3|UniProtKB=A0A2I2Z913 A0A2I2Z913 CDK5 PTHR24056:SF594 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 5 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron apoptotic process#GO:0051402;cellular localization#GO:0051641;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;apoptotic process#GO:0006915;cell differentiation#GO:0030154;cell projection organization#GO:0030030;establishment of organelle localization#GO:0051656;cell morphogenesis#GO:0000902;cell development#GO:0048468;developmental process#GO:0032502;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;axon development#GO:0061564;vesicle localization#GO:0051648;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;organelle localization#GO:0051640;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;programmed cell death#GO:0012501;cell death#GO:0008219 membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Axon guidance mediated by semaphorins#P00007>Cdk5#P00336;Dopamine receptor mediated signaling pathway#P05912>CDK5#P05951;Nicotine pharmacodynamics pathway#P06587>CDK5#P06597;PDGF signaling pathway#P00047>GSK3#P01153;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902 GORGO|Ensembl=ENSGGOG00000009034.3|UniProtKB=G3R0Y5 G3R0Y5 PTHR22957:SF621 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 2B enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000012127.3|UniProtKB=G3R8W2 G3R8W2 LOC101131460 PTHR22839:SF0 THO COMPLEX SUBUNIT 3 THO3 THO COMPLEX SUBUNIT 3 nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;transcription export complex#GO:0000346;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013485.3|UniProtKB=G3RCC5 G3RCC5 PLA2G2E PTHR11716:SF56 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP IIE SECRETORY PHOSPHOLIPASE A2 binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;lipase activity#GO:0016298;small molecule binding#GO:0036094;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;hydrolase activity, acting on ester bonds#GO:0016788 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;phosphatidylglycerol metabolic process#GO:0046471;phosphatidylcholine metabolic process#GO:0046470;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000025175.2|UniProtKB=G3RUU9 G3RUU9 SPINK13 PTHR21312:SF36 SERINE PROTEASE INHIBITOR SERINE PROTEASE INHIBITOR KAZAL-TYPE 13 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000000267.3|UniProtKB=G3QDE8 G3QDE8 EIF2B3 PTHR45989:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT GAMMA translation factor activity#GO:0180051;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152 guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000007520.3|UniProtKB=G3SEJ4 G3SEJ4 CA6 PTHR18952:SF110 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 6 catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000011366.3|UniProtKB=G3R6W6 G3R6W6 PTHR17271:SF10 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN TRIO AND F-ACTIN-BINDING PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000039645.1|UniProtKB=G3RNR3 G3RNR3 SNRPG PTHR10553:SF16 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;P granule#GO:0043186;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;small nuclear ribonucleoprotein complex#GO:0030532;SMN-Sm protein complex#GO:0034719;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U12-type spliceosomal complex#GO:0005689;U1 snRNP#GO:0005685;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;cytoplasmic ribonucleoprotein granule#GO:0036464;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000003923.3|UniProtKB=G3QMV2 G3QMV2 PRKAR2B PTHR11635:SF156 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE II-BETA REGULATORY SUBUNIT protein kinase binding#GO:0019901;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;protein kinase A binding#GO:0051018;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;kinase inhibitor activity#GO:0019210;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;enzyme inhibitor activity#GO:0004857;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829;serine/threonine protein kinase complex#GO:1902554;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;GABA-B receptor II signaling#P05731>PKA#P05752;Endothelin signaling pathway#P00019>PKA#P00570;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Hedgehog signaling pathway#P00025>PKA#P00682;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491 GORGO|Ensembl=ENSGGOG00000043485.1|UniProtKB=A0A2I2YPA4 A0A2I2YPA4 PRR23C PTHR31813:SF6 PROLINE-RICH PROTEIN 23B PROLINE-RICH PROTEIN 23C GORGO|Ensembl=ENSGGOG00000013726.3|UniProtKB=A0A2I2Z1Q0 A0A2I2Z1Q0 PTHR23167:SF51 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;cytoskeletal protein binding#GO:0008092;oxidoreductase activity#GO:0016491;binding#GO:0005488;actin binding#GO:0003779;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament depolymerization#GO:0030042;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008727.3|UniProtKB=G3R055 G3R055 PTHR16181:SF36 PROTEIN FAM83A-RELATED PROTEIN FAM83E protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 GORGO|Ensembl=ENSGGOG00000008284.3|UniProtKB=G3QZ00 G3QZ00 PLA2G2A PTHR11716:SF9 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2, MEMBRANE ASSOCIATED calcium ion binding#GO:0005509;binding#GO:0005488;lipid binding#GO:0008289;metal ion binding#GO:0046872;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipid binding#GO:0005543;catalytic activity#GO:0003824 regulation of mononuclear cell proliferation#GO:0032944;cellular process#GO:0009987;regulation of T cell activation#GO:0050863;glycerophospholipid metabolic process#GO:0006650;negative regulation of cell-cell adhesion#GO:0022408;phosphatidylcholine metabolic process#GO:0046470;regulation of multicellular organismal process#GO:0051239;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;metabolic process#GO:0008152;regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;regulation of lymphocyte activation#GO:0051249;negative regulation of cell population proliferation#GO:0008285;organophosphate metabolic process#GO:0019637;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;lipid metabolic process#GO:0006629;negative regulation of cell activation#GO:0050866;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of T cell proliferation#GO:0042129;phosphatidylglycerol metabolic process#GO:0046471;phospholipid metabolic process#GO:0006644;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000002112.3|UniProtKB=G3QI75 G3QI75 C1H1orf94 PTHR35674:SF1 CDNA SEQUENCE CK137956 CDNA SEQUENCE CK137956 GORGO|Ensembl=ENSGGOG00000013303.3|UniProtKB=G3RBV5 G3RBV5 DMRT3 PTHR12322:SF120 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 sex differentiation#GO:0007548;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000043376.1|UniProtKB=A0A2I2YY42 A0A2I2YY42 PGGHG PTHR11051:SF17 GLYCOSYL HYDROLASE-RELATED PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;glucosidase activity#GO:0015926 carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 glycosidase#PC00110;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000025907.2|UniProtKB=A0A2I2ZGG1 A0A2I2ZGG1 PTHR43066:SF16 RHOMBOID-RELATED PROTEIN RHOMBOID DOMAIN-CONTAINING PROTEIN 3 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000027304.2|UniProtKB=G3S1L3 G3S1L3 TMEM35A PTHR13163:SF0 SPINAL CORD EXPRESSION PROTEIN 4 NOVEL ACETYLCHOLINE RECEPTOR CHAPERONE molecular function regulator activity#GO:0098772;neurotransmitter receptor regulator activity#GO:0099602;signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548 protein-containing complex organization#GO:0043933;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;cellular component organization or biogenesis#GO:0071840;chaperone-mediated protein complex assembly#GO:0051131;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of biological process#GO:0048518;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000002230.3|UniProtKB=G3QII4 G3QII4 THEM5 PTHR47362:SF1 ACYL-COENZYME A THIOESTERASE THEM5 ACYL-COENZYME A THIOESTERASE THEM5 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 hydrolase#PC00121;esterase#PC00097 GORGO|Ensembl=ENSGGOG00000038455.1|UniProtKB=A0A2I2ZIQ2 A0A2I2ZIQ2 PTHR38502:SF1 OVEREXPRESSED IN COLON CARCINOMA 1 PROTEIN OVEREXPRESSED IN COLON CARCINOMA 1 PROTEIN GORGO|Ensembl=ENSGGOG00000002881.3|UniProtKB=A0A2I2YHP2 A0A2I2YHP2 LOC101143714 PTHR12155:SF46 SCHLAFEN SCHLAFEN FAMILY MEMBER 12-LIKE endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000010223.3|UniProtKB=G3SEL8 G3SEL8 ANXA3 PTHR10502:SF25 ANNEXIN ANNEXIN A3 anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phospholipid binding#GO:0005543;ion binding#GO:0043167;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000038280.1|UniProtKB=G3RGJ6 G3RGJ6 PTHR11967:SF3 ALPHA-1-ACID GLYCOPROTEIN ALPHA-1-ACID GLYCOPROTEIN 2 response to stimulus#GO:0050896;acute inflammatory response#GO:0002526;defense response#GO:0006952;immune system process#GO:0002376;response to stress#GO:0006950;immune response#GO:0006955;inflammatory response#GO:0006954 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004700.3|UniProtKB=G3QPV5 G3QPV5 ADCY4 PTHR45627:SF10 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 4 phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760 GORGO|Ensembl=ENSGGOG00000014338.3|UniProtKB=G3REJ6 G3REJ6 ZNF484 PTHR24390:SF274 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 484 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000027277.2|UniProtKB=G3RW39 G3RW39 BORCS7 PTHR31397:SF1 BLOC-1-RELATED COMPLEX SUBUNIT 7 BORSC7 BLOC-1-RELATED COMPLEX SUBUNIT 7 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000011873.3|UniProtKB=G3R877 G3R877 TKTL2 PTHR43195:SF4 TRANSKETOLASE TRANSKETOLASE-LIKE PROTEIN 2 ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;transketolase activity#GO:0004802;cation binding#GO:0043169;catalytic activity#GO:0003824;transferase activity#GO:0016740;transketolase or transaldolase activity#GO:0016744;heterocyclic compound binding#GO:1901363 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transketolase#PC00221;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000037147.1|UniProtKB=A0A2I2Y6R3 A0A2I2Y6R3 PTHR10966:SF3 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA GAMMA CHAIN transcription factor binding#GO:0008134;binding#GO:0005488;protein binding#GO:0005515 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000016827.3|UniProtKB=G3RKY8 G3RKY8 CD19 PTHR16674:SF2 B-LYMPHOCYTE ANTIGEN CD19 B-LYMPHOCYTE ANTIGEN CD19 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor complex adaptor activity#GO:0030159;signaling adaptor activity#GO:0035591 cell communication#GO:0007154;regulation of immune response#GO:0050776;immune system process#GO:0002376;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 B cell activation#P00010>CD19#P00393 GORGO|Ensembl=ENSGGOG00000017113.3|UniProtKB=G3RLP5 G3RLP5 SLC22A17 PTHR24064:SF216 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 17 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;metal ion transport#GO:0030001;transport#GO:0006810;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826;iron coordination entity transport#GO:1901678;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000015275.3|UniProtKB=G3RGZ3 G3RGZ3 MFSD2A PTHR11328:SF29 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;organophosphate ester transmembrane transporter activity#GO:0015605;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monocarboxylic acid transmembrane transporter activity#GO:0008028;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular component organization#GO:0016043;carbohydrate derivative transport#GO:1901264;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;lipid localization#GO:0010876;circulatory system process#GO:0003013;localization#GO:0051179;fatty acid transport#GO:0015908;transmembrane transport#GO:0055085;monocarboxylic acid transport#GO:0015718;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;multicellular organismal process#GO:0032501;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;system process#GO:0003008;regulation of membrane lipid distribution#GO:0097035 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000004628.3|UniProtKB=G3QPN4 G3QPN4 KXD1 PTHR13511:SF0 KXDL MOTIF-CONTAINING PROTEIN 1 KXDL MOTIF-CONTAINING PROTEIN 1 localization#GO:0051179;lysosome localization#GO:0032418;organelle localization#GO:0051640 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000022622.2|UniProtKB=G3RZN8 G3RZN8 BMP2 PTHR11848:SF143 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 2 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;osteoblast differentiation#GO:0001649;cellular response to growth factor stimulus#GO:0071363;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;animal organ development#GO:0048513;heart morphogenesis#GO:0003007;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;ossification#GO:0001503;animal organ morphogenesis#GO:0009887;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;response to BMP#GO:0071772;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817 GORGO|Ensembl=ENSGGOG00000011264.3|UniProtKB=A0A2I2ZH09 A0A2I2ZH09 HSD17B7 PTHR44442:SF1 3-KETO-STEROID REDUCTASE 3-KETO-STEROID REDUCTASE_17-BETA-HYDROXYSTEROID DEHYDROGENASE 7 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;cholesterol biosynthetic process#GO:0006695;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281;hormone biosynthetic process#GO:0042446;secondary alcohol metabolic process#GO:1902652;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 metabolite interconversion enzyme#PC00262;reductase#PC00198 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 GORGO|Ensembl=ENSGGOG00000016267.4|UniProtKB=G3RJI2 G3RJI2 MTMR9 PTHR10807:SF56 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 9 protein binding#GO:0005515;hydrolase activity#GO:0016787;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;phosphoric ester hydrolase activity#GO:0042578;protein phosphatase binding#GO:0019903;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of catabolic process#GO:0009895;dephosphorylation#GO:0016311;phosphatidylinositol dephosphorylation#GO:0046856;phospholipid metabolic process#GO:0006644;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;biological regulation#GO:0065007;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;organophosphate metabolic process#GO:0019637 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000022048.2|UniProtKB=G3SFH3 G3SFH3 PTHR10358:SF4 ENDOSULFINE CAMP-REGULATED PHOSPHOPROTEIN 19 protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000009473.3|UniProtKB=G3R217 G3R217 GRIN3A PTHR18966:SF397 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3A voltage-gated channel activity#GO:0022832;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803 response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NR3#P01009;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Huntington disease#P00029>NMDA receptor#P00778;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071 GORGO|Ensembl=ENSGGOG00000024963.2|UniProtKB=G3RY15 G3RY15 PTHR13080:SF12 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE MEMBRANE SUBUNIT F monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324 ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;small molecule metabolic process#GO:0044281;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000003783.3|UniProtKB=G3QMH3 G3QMH3 TEX13A PTHR23111:SF64 ZINC FINGER PROTEIN TESTIS-EXPRESSED PROTEIN 13A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 GORGO|Ensembl=ENSGGOG00000000214.3|UniProtKB=G3QDA0 G3QDA0 WWTR1 PTHR17616:SF6 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER WW DOMAIN-CONTAINING TRANSCRIPTION REGULATOR PROTEIN 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signaling#GO:0023051;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of canonical Wnt signaling pathway#GO:0060828;hippo signaling#GO:0035329;positive regulation of macromolecule metabolic process#GO:0010604 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000001219.3|UniProtKB=G3RT79 G3RT79 MASP1 PTHR24255:SF13 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MANNAN-BINDING LECTIN SERINE PROTEASE 1 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;immune response#GO:0006955;activation of immune response#GO:0002253;complement activation#GO:0006956;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000016492.3|UniProtKB=G3RK28 G3RK28 POP7 PTHR15314:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P20 RIBONUCLEASE P PROTEIN SUBUNIT P20 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009295.3|UniProtKB=G3R1K3 G3R1K3 SPOP PTHR24413:SF97 SPECKLE-TYPE POZ PROTEIN SPECKLE-TYPE POZ PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000001822.3|UniProtKB=G3QHG7 G3QHG7 STYX PTHR46588:SF1 SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of protein catabolic process#GO:0042177 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000016021.3|UniProtKB=G3RIW5 G3RIW5 FHIP1B PTHR21705:SF4 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 1B intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;lytic vacuole organization#GO:0080171;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle organization#GO:0016050;endosome organization#GO:0007032;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000002294.3|UniProtKB=G3QIP4 G3QIP4 HABP2 PTHR24264:SF40 TRYPSIN-RELATED FACTOR VII-ACTIVATING PROTEASE catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000007115.3|UniProtKB=G3RS92 G3RS92 ARAP2 PTHR45899:SF1 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;phosphatidylinositol phosphate binding#GO:1901981;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 regulation of actin filament-based process#GO:0032970;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000025134.2|UniProtKB=A0A2I2Y7X4 A0A2I2Y7X4 PTHR12599:SF15 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE 2 dehydratase#PC00091;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000024288.2|UniProtKB=G3SBD1 G3SBD1 PNN PTHR12707:SF0 PINN PININ intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 GORGO|Ensembl=ENSGGOG00000010233.3|UniProtKB=G3R403 G3R403 NECAP1 PTHR12847:SF15 ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED ADAPTIN EAR-BINDING COAT-ASSOCIATED PROTEIN 1 intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle coat#GO:0030120 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000002675.3|UniProtKB=G3QJN8 G3QJN8 ACSL3 PTHR43272:SF13 LONG-CHAIN-FATTY-ACID--COA LIGASE FATTY ACID COA LIGASE ACSL3 catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;neurogenesis#GO:0022008;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;lipid metabolic process#GO:0006629;developmental process#GO:0032502;neuron differentiation#GO:0030182;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637 lipid droplet#GO:0005811;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000004721.3|UniProtKB=G3QPX0 G3QPX0 ECHS1 PTHR11941:SF179 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE, MITOCHONDRIAL cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000004152.2|UniProtKB=G3QNF7 G3QNF7 LOC101124310 PTHR26452:SF186 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AU1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000015967.3|UniProtKB=G3RIR6 G3RIR6 ARHGEF28 PTHR13944:SF22 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 28 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;signal transduction#GO:0007165 CCKR signaling map#P06959>p190RhoGEF#P07157 GORGO|Ensembl=ENSGGOG00000003208.3|UniProtKB=A0A2K5TIX5 A0A2K5TIX5 RNASE9 PTHR11437:SF14 RIBONUCLEASE INACTIVE RIBONUCLEASE-LIKE PROTEIN 9 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098 defense response to Gram-positive bacterium#GO:0050830;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;defense response#GO:0006952;response to external stimulus#GO:0009605 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005487.3|UniProtKB=G3SJL7 G3SJL7 CDX2 PTHR24332:SF27 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular process#GO:0009987;embryonic pattern specification#GO:0009880;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;tube development#GO:0035295;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;anterior/posterior axis specification#GO:0009948;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000009415.3|UniProtKB=G3R1W6 G3R1W6 IL1F10 PTHR10078:SF29 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 FAMILY MEMBER 10 signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;cellular response to molecule of bacterial origin#GO:0071219;defense response#GO:0006952;response to external stimulus#GO:0009605;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;cell communication#GO:0007154;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;interleukin superfamily#PC00128;cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000002810.3|UniProtKB=G3QK11 G3QK11 PRSS12 PTHR48071:SF5 SRCR DOMAIN-CONTAINING PROTEIN NEUROTRYPSIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;zymogen activation#GO:0031638;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 synapse#GO:0045202;cellular anatomical structure#GO:0110165;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306;cell projection#GO:0042995;dendrite#GO:0030425;extracellular region#GO:0005576;axon#GO:0030424;dendritic tree#GO:0097447;glutamatergic synapse#GO:0098978;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;presynapse#GO:0098793;cell junction#GO:0030054;axon terminus#GO:0043679 GORGO|Ensembl=ENSGGOG00000026573.2|UniProtKB=G3SF11 G3SF11 PPP1R14C PTHR16188:SF6 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14C protein serine/threonine phosphatase inhibitor activity#GO:0004865;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000010421.3|UniProtKB=G3R4G6 G3R4G6 SNX15 PTHR15508:SF9 RIBOSOMAL PROTEIN S6 KINASE SORTING NEXIN-15 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015886.3|UniProtKB=G3RII8 G3RII8 SLC25A3 PTHR45671:SF10 SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 3 secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 mitochondrial carrier protein#PC00158 GORGO|Ensembl=ENSGGOG00000039484.1|UniProtKB=G3S5Y1 G3S5Y1 PTHR23268:SF14 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 12-3-RELATED cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014235.3|UniProtKB=G3REA4 G3REA4 CUEDC1 PTHR13467:SF3 CUE DOMAIN CONTAINING PROTEIN 1 CUE DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000024796.2|UniProtKB=A0A2I2ZME2 A0A2I2ZME2 OXSM PTHR11712:SF362 POLYKETIDE SYNTHASE-RELATED 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 GORGO|Ensembl=ENSGGOG00000004765.3|UniProtKB=G3QQ11 G3QQ11 GCNT2 PTHR19297:SF183 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER N-ACETYLLACTOSAMINIDE BETA-1,6-N-ACETYLGLUCOSAMINYL-TRANSFERASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to transforming growth factor beta#GO:0071559;signaling#GO:0023052;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000003294.3|UniProtKB=G3QL89 G3QL89 NQO1 PTHR10204:SF1 NAD P H OXIDOREDUCTASE-RELATED NAD(P)H DEHYDROGENASE [QUINONE] 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000015360.3|UniProtKB=G3RUG1 G3RUG1 MASP2 PTHR24255:SF10 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MANNAN-BINDING LECTIN SERINE PROTEASE 2 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;complement activation#GO:0006956;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000009527.3|UniProtKB=G3R269 G3R269 SLC43A1 PTHR20766:SF0 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 3 neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;localization#GO:0051179;amino acid transport#GO:0006865;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000041395.1|UniProtKB=G3QYJ6 G3QYJ6 LOC101124042 PTHR24103:SF632 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM48 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;defense response to symbiont#GO:0140546;immune response#GO:0006955;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;immune system process#GO:0002376;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000007496.3|UniProtKB=G3QX12 G3QX12 NCBP3 PTHR16291:SF0 NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3 NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009796.3|UniProtKB=G3R2W9 G3R2W9 GNPTAB PTHR24045:SF1 FAMILY NOT NAMED N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNITS ALPHA_BETA phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein transport#GO:0015031;cellular localization#GO:0051641;lysosomal transport#GO:0007041;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;protein localization to lysosome#GO:0061462;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040;organelle organization#GO:0006996;protein targeting to vacuole#GO:0006623;vacuole organization#GO:0007033;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;lytic vacuole organization#GO:0080171;intracellular transport#GO:0046907;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000034833.2|UniProtKB=G3SKL8 G3SKL8 OR2A2 PTHR26453:SF82 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Gene=MC1R|UniProtKB=Q864K9 Q864K9 MC1R PTHR22750:SF2 G-PROTEIN COUPLED RECEPTOR MELANOCYTE-STIMULATING HORMONE RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 positive regulation of response to stimulus#GO:0048584;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;pigment metabolic process#GO:0042440;positive regulation of cellular process#GO:0048522;secondary metabolic process#GO:0019748;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of response to stimulus#GO:0048583;pigment biosynthetic process#GO:0046148;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;phenol-containing compound biosynthetic process#GO:0046189;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;secondary metabolite biosynthetic process#GO:0044550;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;phenol-containing compound metabolic process#GO:0018958;melanin biosynthetic process#GO:0042438;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000011713.3|UniProtKB=G3SCY0 G3SCY0 SAG PTHR11792:SF15 ARRESTIN S-ARRESTIN G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 nervous system process#GO:0050877;regulation of signaling#GO:0023051;sensory perception#GO:0007600;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;localization#GO:0051179;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;transport#GO:0006810;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;system process#GO:0003008;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;receptor internalization#GO:0031623;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;photoreceptor inner segment#GO:0001917;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005 scaffold/adaptor protein#PC00226 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>beta-arrestin#P00757;Wnt signaling pathway#P00057>beta-arrestin#P01456 GORGO|Ensembl=ENSGGOG00000022153.2|UniProtKB=G3S3R9 G3S3R9 CNTF PTHR15196:SF0 CILIARY NEUROTROPHIC FACTOR CILIARY NEUROTROPHIC FACTOR signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515 cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of neuron apoptotic process#GO:0043524;response to stress#GO:0006950;regulation of response to wounding#GO:1903034;regulation of neuron apoptotic process#GO:0043523;nervous system development#GO:0007399;cell surface receptor signaling pathway via STAT#GO:0097696;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;gliogenesis#GO:0042063;positive regulation of response to external stimulus#GO:0032103;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cell development#GO:0048468;signaling#GO:0023052;central nervous system development#GO:0007417;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;response to stimulus#GO:0050896;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;positive regulation of neuron projection development#GO:0010976;response to peptide#GO:1901652;regulation of cellular response to stress#GO:0080135;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;defense response#GO:0006952;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular response to stimulus#GO:0051716;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell projection organization#GO:0031346;cell activation#GO:0001775;inflammatory response#GO:0006954;cytokine-mediated signaling pathway#GO:0019221;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154 axon#GO:0030424;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;cell body#GO:0044297;neuron projection#GO:0043005 GORGO|Ensembl=ENSGGOG00000008260.3|UniProtKB=G3QYX5 G3QYX5 PLAC8L1 PTHR15907:SF122 DUF614 FAMILY PROTEIN-RELATED PLAC8-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000008381.3|UniProtKB=A0A2I2Z2L1 A0A2I2Z2L1 HSPA8 PTHR19375:SF597 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;localization#GO:0051179;protein refolding#GO:0042026;endocytosis#GO:0006897;protein folding#GO:0006457;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;clathrin-dependent endocytosis#GO:0072583;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;metabolic process#GO:0008152;transport#GO:0006810;vesicle-mediated transport#GO:0016192;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 GORGO|Ensembl=ENSGGOG00000012692.3|UniProtKB=G3RAC4 G3RAC4 PTHR23167:SF18 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED CYTOSPIN-A organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000038752.1|UniProtKB=A0A2I2YD66 A0A2I2YD66 PTHR12773:SF0 UPF0315 PROTEIN-RELATED MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011512.3|UniProtKB=G3R799 G3R799 GPCPD1 PTHR22958:SF43 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010665.3|UniProtKB=G3SCV4 G3SCV4 ZNF606 PTHR24377:SF1048 IP01015P-RELATED ZINC FINGER PROTEIN 606 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003629.3|UniProtKB=G3QM41 G3QM41 LMX1B PTHR24204:SF7 INSULIN GENE ENHANCER PROTEIN LIM ZINC-BINDING DOMAIN-CONTAINING PROTEIN DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell fate specification#GO:0001708;positive regulation of transcription by RNA polymerase II#GO:0045944;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell fate commitment#GO:0045165;neuron development#GO:0048666;axonogenesis#GO:0007409;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;neuron fate commitment#GO:0048663;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002725.3|UniProtKB=G3SHF2 G3SHF2 GMPPA PTHR22572:SF104 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE REGULATORY SUBUNIT ALPHA nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 GORGO|Ensembl=ENSGGOG00000013351.3|UniProtKB=G3RC05 G3RC05 TOR1B PTHR10760:SF14 TORSIN TORSIN-1B protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 intracellular protein localization#GO:0008104;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;nucleus organization#GO:0006997;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein localization to organelle#GO:0033365;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;protein localization to nucleus#GO:0034504 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000004233.3|UniProtKB=A0A2I2YLP0 A0A2I2YLP0 PCDH7 PTHR24028:SF253 CADHERIN-87A PROTOCADHERIN-7 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000003741.2|UniProtKB=G3QMD7 G3QMD7 PTHR45696:SF11 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 enzyme activator activity#GO:0008047;structural constituent of ribosome#GO:0003735;protein kinase activator activity#GO:0030295;kinase regulator activity#GO:0019207;structural molecule activity#GO:0005198;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;binding#GO:0005488;enzyme regulator activity#GO:0030234;ribonucleoprotein complex binding#GO:0043021;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009110.3|UniProtKB=G3R151 G3R151 MSX1 PTHR24338:SF8 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;regulation of gene expression#GO:0010468;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000016528.3|UniProtKB=G3S517 G3S517 SPINK4 PTHR21179:SF0 SERINE-TYPE ENDOPEPTIDASE INHIBITOR SERINE PROTEASE INHIBITOR KAZAL-TYPE 4 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000013935.3|UniProtKB=G3RY44 G3RY44 ALYREF PTHR19965:SF35 RNA AND EXPORT FACTOR BINDING PROTEIN THO COMPLEX SUBUNIT 4 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000039116.1|UniProtKB=A0A2I2YRW4 A0A2I2YRW4 SPEGNB PTHR47633:SF8 IMMUNOGLOBULIN SPEG NEIGHBOR PROTEIN GORGO|Ensembl=ENSGGOG00000007365.3|UniProtKB=A0A2I2ZVK8 A0A2I2ZVK8 EARS2 PTHR43311:SF2 GLUTAMATE--TRNA LIGASE NONDISCRIMINATING GLUTAMYL-TRNA SYNTHETASE EARS2, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 GORGO|Ensembl=ENSGGOG00000011941.3|UniProtKB=G3R8E9 G3R8E9 SLC4A11 PTHR11453:SF127 ANION EXCHANGE PROTEIN SOLUTE CARRIER FAMILY 4 MEMBER 11 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;bicarbonate transmembrane transporter activity#GO:0015106 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;homeostatic process#GO:0042592;transport#GO:0006810;chemical homeostasis#GO:0048878;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000001559.3|UniProtKB=G3QGS8 G3QGS8 KCNH3 PTHR10217:SF481 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED INWARDLY RECTIFYING POTASSIUM CHANNEL KCNH3 potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873 transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003876.3|UniProtKB=G3SIB4 G3SIB4 PTHR24393:SF187 ZINC FINGER PROTEIN ZINC FINGER PROTEIN nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000022179.2|UniProtKB=G3RM47 G3RM47 LOC101149104 PTHR11818:SF119 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN A structural molecule activity#GO:0005198 visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000014288.3|UniProtKB=G3REF1 G3REF1 D2HGDH PTHR43716:SF5 D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000000329.3|UniProtKB=G3QDK1 G3QDK1 PTHR15427:SF5 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-2 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 regulation of platelet activation#GO:0010543;regulation of angiogenesis#GO:0045765;positive regulation of cell adhesion#GO:0045785;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of developmental process#GO:0050793;regulation of vasculature development#GO:1901342;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of developmental process#GO:0051094;regulation of hemostasis#GO:1900046;positive regulation of cellular process#GO:0048522;regulation of cell adhesion#GO:0030155;regulation of coagulation#GO:0050818;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of platelet aggregation#GO:0090330;positive regulation of coagulation#GO:0050820;regulation of biological quality#GO:0065008;positive regulation of angiogenesis#GO:0045766;regulation of cell activation#GO:0050865;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;regulation of wound healing#GO:0061041;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of cell-cell adhesion#GO:0022409;regulation of response to wounding#GO:1903034;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239 interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;protein complex involved in cell adhesion#GO:0098636;supramolecular fiber#GO:0099512;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040591.1|UniProtKB=A0A2I2ZFS7 A0A2I2ZFS7 PTHR45961:SF5 IP21249P DUAL SPECIFICITY PROTEIN PHOSPHATASE 14 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000001087.3|UniProtKB=G3QFJ7 G3QFJ7 APOBR PTHR15964:SF0 APOLIPOPROTEIN B48 RECEPTOR APOLIPOPROTEIN B RECEPTOR cargo receptor activity#GO:0038024 triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid metabolic process#GO:0006638;cellular process#GO:0009987;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000007154.3|UniProtKB=A0A2I2YUP5 A0A2I2YUP5 PTHR46542:SF1 X-BOX BINDING PROTEIN 1 X-BOX-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000002767.3|UniProtKB=G3QJW9 G3QJW9 BEND4 PTHR35082:SF1 BEN DOMAIN-CONTAINING PROTEIN 4 BEN DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000025940.2|UniProtKB=G3S3R3 G3S3R3 LOC101133388 PTHR12015:SF196 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 3 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000014753.3|UniProtKB=G3RFM8 G3RFM8 UBXN7 PTHR23322:SF6 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 7 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008975.3|UniProtKB=G3R0T8 G3R0T8 ANO2 PTHR12308:SF20 ANOCTAMIN ANOCTAMIN-2 passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;intramembrane lipid carrier activity#GO:0140303;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;gated channel activity#GO:0022836 lipid localization#GO:0010876;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;cellular component organization#GO:0016043;monoatomic anion transport#GO:0006820;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;lipid transport#GO:0006869;monoatomic ion transmembrane transport#GO:0034220;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000006459.3|UniProtKB=G3QUB5 G3QUB5 ZNF114 PTHR24377:SF900 IP01015P-RELATED ZINC FINGER PROTEIN 577 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002189.3|UniProtKB=G3QIF0 G3QIF0 ITGAL PTHR23220:SF84 INTEGRIN ALPHA INTEGRIN ALPHA-L signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 GORGO|Ensembl=ENSGGOG00000038178.1|UniProtKB=A0A2I2Y879 A0A2I2Y879 PTHR21141:SF120 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN P2 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000027749.2|UniProtKB=G3RZ05 G3RZ05 RPL35A PTHR10902:SF36 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;translation#GO:0006412;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000038986.1|UniProtKB=A0A2I2Z4Y2 A0A2I2Z4Y2 TCF24 PTHR23349:SF48 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 24 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000013326.3|UniProtKB=G3S0M1 G3S0M1 FBH1 PTHR11070:SF30 UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER F-BOX DNA HELICASE 1 nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000013666.3|UniProtKB=G3RCU4 G3RCU4 CDR2 PTHR19232:SF1 CENTROCORTIN FAMILY MEMBER CEREBELLAR DEGENERATION-RELATED PROTEIN 2 GORGO|Ensembl=ENSGGOG00000015474.3|UniProtKB=G3RHH9 G3RHH9 DDX27 PTHR24031:SF706 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX27-RELATED ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000028074.2|UniProtKB=G3RQE9 G3RQE9 UPP1 PTHR43691:SF10 URIDINE PHOSPHORYLASE URIDINE PHOSPHORYLASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 nucleoside catabolic process#GO:0009164;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 GORGO|Ensembl=ENSGGOG00000012508.3|UniProtKB=G3SI42 G3SI42 SHTN1 PTHR46606:SF3 SHOOTIN-1 SHOOTIN-1 regulation of neuron migration#GO:2001222;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;system development#GO:0048731;regulation of cellular process#GO:0050794;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468 axon#GO:0030424;growth cone#GO:0030426;axonal growth cone#GO:0044295;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;cell leading edge#GO:0031252;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;distal axon#GO:0150034;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000000840.3|UniProtKB=G3SCD8 G3SCD8 REN PTHR47966:SF24 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED RENIN catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;proteolysis#GO:0006508;circulatory system process#GO:0003013;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;peptide hormone processing#GO:0016486;hormone metabolic process#GO:0042445;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;system process#GO:0003008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;aspartic protease#PC00053 GORGO|Ensembl=ENSGGOG00000010972.3|UniProtKB=G3R5V9 G3R5V9 CFLAR PTHR10454:SF239 CASPASE CASP8 AND FADD-LIKE APOPTOSIS REGULATOR molecular function inhibitor activity#GO:0140678;molecular function activator activity#GO:0140677;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme regulator activity#GO:0030234;peptidase inhibitor activity#GO:0030414;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;enzyme activator activity#GO:0008047;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;cysteine-type endopeptidase activity#GO:0004197;endopeptidase inhibitor activity#GO:0004866;catalytic activity, acting on a protein#GO:0140096;enzyme inhibitor activity#GO:0004857;peptidase activator activity#GO:0016504;catalytic activity#GO:0003824 anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cellular process#GO:0050794;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic signaling pathway#GO:0097190;cellular developmental process#GO:0048869;positive regulation of neuron apoptotic process#GO:0043525;developmental process#GO:0032502;hemopoiesis#GO:0030097;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of programmed cell death#GO:0043068;myeloid cell differentiation#GO:0030099;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;leukocyte differentiation#GO:0002521;regulation of programmed cell death#GO:0043067;mononuclear cell differentiation#GO:1903131;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of apoptotic process#GO:0043065;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;peptidase complex#GO:1905368;cytoplasm#GO:0005737;caspase complex#GO:0008303;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 FAS signaling pathway#P00020>Pro-Caspase8#P00604;FAS signaling pathway#P00020>Caspase8#P00594;Apoptosis signaling pathway#P00006>Flip#P00284 GORGO|Ensembl=ENSGGOG00000012970.3|UniProtKB=G3RB12 G3RB12 HSD11B2 PTHR43313:SF2 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 steroid metabolic process#GO:0008202;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007484.3|UniProtKB=G3RWA5 G3RWA5 HTR3D PTHR18945:SF409 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3D monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857 response to nitrogen compound#GO:1901698;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000001134.3|UniProtKB=G3QFP1 G3QFP1 LOC101128351 PTHR24379:SF93 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 439 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000013214.3|UniProtKB=G3RBM8 G3RBM8 ACSM2B PTHR43605:SF3 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM2B, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ligase activity, forming carbon-sulfur bonds#GO:0016877 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012398.3|UniProtKB=G3R9L5 G3R9L5 RHAG PTHR11730:SF32 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE A passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267 homeostatic process#GO:0042592;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000011471.3|UniProtKB=G3R763 G3R763 XRCC5 PTHR12604:SF4 KU AUTOANTIGEN DNA HELICASE DNA REPAIR PROTEIN KU80 double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 telomere organization#GO:0032200;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;double-strand break repair via nonhomologous end joining#GO:0006303;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 DNA helicase#PC00011 GORGO|Ensembl=ENSGGOG00000009872.4|UniProtKB=A0A2I2Z8W7 A0A2I2Z8W7 RTN3 PTHR45799:SF4 RETICULON-LIKE PROTEIN RETICULON-3 endoplasmic reticulum tubular network organization#GO:0071786;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000043123.1|UniProtKB=A0A2I2YN87 A0A2I2YN87 PRLR PTHR23036:SF86 CYTOKINE RECEPTOR PROLACTIN RECEPTOR cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515 positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PRLR#P06822 GORGO|Ensembl=ENSGGOG00000040849.1|UniProtKB=A0A2I2YD41 A0A2I2YD41 DUSP28 PTHR45961:SF7 IP21249P DUAL SPECIFICITY PHOSPHATASE 28 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000036236.1|UniProtKB=A0A2I2YHQ8 A0A2I2YHQ8 CFAP299 PTHR33588:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000006569.3|UniProtKB=G3QUM8 G3QUM8 CDK8 PTHR24056:SF243 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 8 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein serine/threonine kinase activity#GO:0004693 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;mediator complex#GO:0016592;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000023097.2|UniProtKB=G3SGX3 G3SGX3 NTHL1 PTHR43286:SF7 ENDONUCLEASE III-LIKE PROTEIN 1 ENDONUCLEASE III-LIKE PROTEIN 1 DNA N-glycosylase activity#GO:0019104;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;endonuclease activity#GO:0004519 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;base-excision repair#GO:0006284;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 GORGO|Ensembl=ENSGGOG00000011255.3|UniProtKB=G3R6L5 G3R6L5 CARS2 PTHR10890:SF27 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000009694.3|UniProtKB=G3R2L6 G3R2L6 FBXL20 PTHR13318:SF47 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 20 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 GORGO|Ensembl=ENSGGOG00000001450.3|UniProtKB=G3QGH4 G3QGH4 CACUL1 PTHR46636:SF1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047 GORGO|Ensembl=ENSGGOG00000005046.3|UniProtKB=G3QQS1 G3QQS1 HERPUD1 PTHR12943:SF7 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 1 PROTEIN transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein binding#GO:0005515 regulation of signal transduction#GO:0009966;negative regulation of apoptotic process#GO:0043066;endoplasmic reticulum unfolded protein response#GO:0030968;intracellular chemical homeostasis#GO:0055082;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular monoatomic cation homeostasis#GO:0030003;regulation of response to stress#GO:0080134;homeostatic process#GO:0042592;catabolic process#GO:0009056;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of protein catabolic process#GO:0042176;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;protein metabolic process#GO:0019538;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;monoatomic ion homeostasis#GO:0050801;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;intracellular calcium ion homeostasis#GO:0006874;regulation of apoptotic process#GO:0042981;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of cellular response to stress#GO:0080135;response to unfolded protein#GO:0006986;negative regulation of intracellular signal transduction#GO:1902532;cellular response to stress#GO:0033554;inorganic ion homeostasis#GO:0098771;modification-dependent macromolecule catabolic process#GO:0043632;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;cellular homeostasis#GO:0019725;macromolecule metabolic process#GO:0043170;monoatomic cation homeostasis#GO:0055080;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of ERAD pathway#GO:1904292;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to topologically incorrect protein#GO:0035967;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of signal transduction#GO:0009968;regulation of proteasomal protein catabolic process#GO:0061136;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;macromolecule catabolic process#GO:0009057;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;intracellular monoatomic ion homeostasis#GO:0006873;negative regulation of cell communication#GO:0010648;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;calcium ion homeostasis#GO:0055074 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000013517.3|UniProtKB=A0A2I2YR07 A0A2I2YR07 TBC1D24 PTHR23353:SF34 RAB-GAP/TBC-RELATED TBC1 DOMAIN FAMILY MEMBER 24 GTPase-activating protein#PC00257 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 GORGO|Ensembl=ENSGGOG00000027183.2|UniProtKB=G3RQZ1 G3RQZ1 SDC3 PTHR10915:SF7 SYNDECAN SYNDECAN-3 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000039553.1|UniProtKB=A0A2I2ZRF2 A0A2I2ZRF2 ZBTB34 PTHR24399:SF42 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 34 nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002936.3|UniProtKB=G3QKB6 G3QKB6 RPS11 PTHR10744:SF9 40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US17 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010933.3|UniProtKB=G3R5T4 G3R5T4 SEC16A PTHR13402:SF13 RGPR-RELATED PROTEIN TRANSPORT PROTEIN SEC16A membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000009740.3|UniProtKB=G3R2Q8 G3R2Q8 KSR2 PTHR23257:SF775 SERINE-THREONINE PROTEIN KINASE KINASE SUPPRESSOR OF RAS 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000040380.1|UniProtKB=A0A2I2ZMY7 A0A2I2ZMY7 ANKRD22 PTHR47276:SF1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 22 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 22 cellular process#GO:0009987;immune response#GO:0006955;response to wounding#GO:0009611;response to stress#GO:0006950;cell migration#GO:0016477;cell motility#GO:0048870;response to stimulus#GO:0050896;leukocyte migration#GO:0050900;immune system process#GO:0002376 GORGO|Ensembl=ENSGGOG00000022451.2|UniProtKB=G3SCN5 G3SCN5 MTRF1L PTHR43804:SF3 LD18447P PEPTIDE CHAIN RELEASE FACTOR 1-LIKE, MITOCHONDRIAL cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex disassembly#GO:0032984;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;translation#GO:0006412;translational termination#GO:0006415;mitochondrial gene expression#GO:0140053;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;translation factor#PC00223;translation release factor#PC00225 GORGO|Ensembl=ENSGGOG00000005562.3|UniProtKB=A0A2I2Z5I7 A0A2I2Z5I7 DENR PTHR12789:SF0 DENSITY-REGULATED PROTEIN HOMOLOG DENSITY-REGULATED PROTEIN binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000003735.3|UniProtKB=G3QMD0 G3QMD0 PTHR11829:SF368 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN E1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000004451.3|UniProtKB=G3QP82 G3QP82 ANXA7 PTHR10502:SF239 ANNEXIN ANNEXIN A7 ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000010307.3|UniProtKB=G3R467 G3R467 TSPO PTHR10057:SF5 PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR TRANSLOCATOR PROTEIN mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000003377.3|UniProtKB=G3QLG8 G3QLG8 PTHR13999:SF25 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN IFITM2 immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to virus#GO:0009615;cell communication#GO:0007154;cellular process#GO:0009987;response to type II interferon#GO:0034341;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;response to peptide#GO:1901652 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000028600.2|UniProtKB=G3RR62 G3RR62 ATP6V0C PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000027747.2|UniProtKB=G3RS96 G3RS96 PTHR24381:SF53 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 404 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003680.3|UniProtKB=G3RE77 G3RE77 PTHR23051:SF0 SOLUTE CARRIER FAMILY 35, MEMBER F5 SOLUTE CARRIER FAMILY 35 MEMBER F5 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000015863.3|UniProtKB=A0A2I2ZLK4 A0A2I2ZLK4 ADCYAP1R1 PTHR45620:SF12 PDF RECEPTOR-LIKE PROTEIN-RELATED PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE TYPE I RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PAC1R#G06898;Gonadotropin-releasing hormone receptor pathway#P06664>PAC1-R#P06712;Gonadotropin-releasing hormone receptor pathway#P06664>PAC1R#G06685 GORGO|Ensembl=ENSGGOG00000012827.3|UniProtKB=G3RAN8 G3RAN8 KCNN3 PTHR10153:SF40 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 3 gated channel activity#GO:0022836;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;transporter activity#GO:0005215;calmodulin binding#GO:0005516;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261 cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell body#GO:0044297;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000027515.2|UniProtKB=G3SG09 G3SG09 ZBED5 PTHR45935:SF34 PROTEIN ZBED8-RELATED ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 5 GORGO|Ensembl=ENSGGOG00000015074.3|UniProtKB=Q2IBF3 Q2IBF3 CAV2 PTHR10844:SF3 CAVEOLIN CAVEOLIN-2 kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;intracellular monoatomic ion homeostasis#GO:0006873;response to endogenous stimulus#GO:0009719;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;plasma membrane organization#GO:0007009;calcium ion homeostasis#GO:0055074;cellular response to chemical stimulus#GO:0070887;inorganic ion homeostasis#GO:0098771;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;response to hormone#GO:0009725;monoatomic ion homeostasis#GO:0050801;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;intracellular calcium ion homeostasis#GO:0006874;cell surface receptor signaling pathway#GO:0007166;chemical homeostasis#GO:0048878;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;homeostatic process#GO:0042592;regulation of cytosolic calcium ion concentration#GO:0051480;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to nitrogen compound#GO:1901699;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;membrane organization#GO:0061024;negative regulation of cell population proliferation#GO:0008285;cellular developmental process#GO:0048869;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;negative regulation of cellular process#GO:0048523;cellular response to insulin stimulus#GO:0032869;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;developmental process#GO:0032502 intracellular vesicle#GO:0097708;membrane raft#GO:0045121;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;plasma membrane raft#GO:0044853;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane#GO:0016020;caveola#GO:0005901;cell periphery#GO:0071944;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;membrane microdomain#GO:0098857;cell junction#GO:0030054;sarcolemma#GO:0042383 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015286.3|UniProtKB=G3RGZ9 G3RGZ9 TRNT1 PTHR46173:SF1 CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL RNA binding#GO:0003723;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;tRNA 3'-end processing#GO:0042780;mitochondrial RNA 3'-end processing#GO:0000965;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001944.3|UniProtKB=G3QDG0 G3QDG0 PLAAT3 PTHR13943:SF82 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 3 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity#GO:0016746;lipase activity#GO:0016298 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;cell differentiation#GO:0030154;visual system development#GO:0150063;phospholipid metabolic process#GO:0006644;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;sensory system development#GO:0048880;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;glycerophospholipid metabolic process#GO:0006650;sensory organ development#GO:0007423;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000039417.1|UniProtKB=G3RX61 G3RX61 ZNF107 PTHR24381:SF417 ZINC FINGER PROTEIN AA987161 PROTEIN DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000025744.2|UniProtKB=A0A2I2Z845 A0A2I2Z845 PTHR16523:SF8 PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006648.3|UniProtKB=G3QUU5 G3QUU5 PBK PTHR43289:SF14 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000007685.3|UniProtKB=G3QXH2 G3QXH2 SCN3B PTHR10546:SF1 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL REGULATORY SUBUNIT BETA-3 binding#GO:0005488;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;molecular function regulator activity#GO:0098772 heart contraction#GO:0060047;system process#GO:0003008;cardiac muscle cell contraction#GO:0086003;establishment of localization#GO:0051234;muscle contraction#GO:0006936;transport#GO:0006810;regulation of system process#GO:0044057;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;actin filament-based movement#GO:0030048;localization#GO:0051179;monoatomic cation transport#GO:0006812;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;circulatory system process#GO:0003013;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;striated muscle contraction#GO:0006941;regulation of heart contraction#GO:0008016;actin-mediated cell contraction#GO:0070252;regulation of membrane potential#GO:0042391;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;cardiac muscle cell action potential involved in contraction#GO:0086002;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;muscle system process#GO:0003012;action potential#GO:0001508;regulation of biological process#GO:0050789;heart process#GO:0003015;sodium ion transport#GO:0006814 sodium channel complex#GO:0034706;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000001277.3|UniProtKB=A0A2I2Z9E9 A0A2I2Z9E9 SLC16A11 PTHR11360:SF80 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 11 monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002167.3|UniProtKB=G3QIC7 G3QIC7 PTHR31997:SF3 AGAP003710-PA DUF3719 DOMAIN-CONTAINING PROTEIN intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;localization#GO:0051179;organelle assembly#GO:0070925;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;cilium assembly#GO:0060271;cellular component organization#GO:0016043 GORGO|Ensembl=ENSGGOG00000009101.3|UniProtKB=Q9N1E4 Q9N1E4 CD22 PTHR46958:SF1 B-CELL RECEPTOR CD22 B-CELL RECEPTOR CD22 protein phosphatase binding#GO:0019903;carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;ion binding#GO:0043167;anion binding#GO:0043168;signaling receptor binding#GO:0005102;binding#GO:0005488;carboxylic acid binding#GO:0031406;phosphatase binding#GO:0019902;small molecule binding#GO:0036094;organic acid binding#GO:0043177;enzyme binding#GO:0019899 negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;lymphocyte activation#GO:0046649;cellular process#GO:0009987;regulation of mononuclear cell proliferation#GO:0032944;regulation of B cell activation#GO:0050864;B cell activation#GO:0042113;regulation of leukocyte proliferation#GO:0070663;regulation of B cell proliferation#GO:0030888;regulation of lymphocyte activation#GO:0051249;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;regulation of lymphocyte proliferation#GO:0050670;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of B cell receptor signaling pathway#GO:0050855;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;leukocyte activation#GO:0045321;regulation of cell population proliferation#GO:0042127;cell activation#GO:0001775;regulation of immune response#GO:0050776 recycling endosome#GO:0055037;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 B cell activation#P00010>CD22#P00387 GORGO|Ensembl=ENSGGOG00000022715.2|UniProtKB=G3S8E7 G3S8E7 EFCAB13 PTHR22656:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 13 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 13 GORGO|Ensembl=ENSGGOG00000006040.3|UniProtKB=G3QT96 G3QT96 IFNG PTHR11419:SF0 INTERFERON GAMMA INTERFERON GAMMA signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;myeloid leukocyte activation#GO:0002274;response to chemical#GO:0042221;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;response to type II interferon#GO:0034341;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to peptide#GO:1901652;immune system process#GO:0002376;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;innate immune response#GO:0045087;macrophage activation#GO:0042116;defense response#GO:0006952;response to external stimulus#GO:0009605;multicellular organismal process#GO:0032501;adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;cell activation#GO:0001775;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interferon superfamily#PC00127;cytokine#PC00083;intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>INFgamma#P00878;Interferon-gamma signaling pathway#P00035>Interferongamma#P00954 GORGO|Ensembl=ENSGGOG00000010439.3|UniProtKB=G3RNN4 G3RNN4 IQCD PTHR31598:SF1 IQ DOMAIN-CONTAINING PROTEIN D DYNEIN REGULATORY COMPLEX SUBUNIT 10 GORGO|Ensembl=ENSGGOG00000039698.1|UniProtKB=A0A2I2YTS9 A0A2I2YTS9 NIPSNAP2 PTHR21017:SF14 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;mitophagy#GO:0000423;process utilizing autophagic mechanism#GO:0061919;cellular process#GO:0009987;autophagy#GO:0006914;catabolic process#GO:0009056;macroautophagy#GO:0016236 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000039835.1|UniProtKB=A0A2I2Y7T4 A0A2I2Y7T4 PTHR11907:SF22 AMIDOPHOSPHORIBOSYLTRANSFERASE AMIDOPHOSPHORIBOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000004696.3|UniProtKB=G3SHH4 G3SHH4 ZNF827 PTHR24403:SF62 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 827 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000012455.3|UniProtKB=A0A2I2YB70 A0A2I2YB70 PHACTR4 PTHR12751:SF4 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 4 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 mesenchyme development#GO:0060485;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;mesenchymal cell differentiation#GO:0048762;neural crest cell differentiation#GO:0014033;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;tissue development#GO:0009888;cell migration#GO:0016477;neural crest cell development#GO:0014032;cellular process#GO:0009987;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;organelle organization#GO:0006996;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;stem cell development#GO:0048864;cell development#GO:0048468;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;cell differentiation#GO:0030154;cellular component organization#GO:0016043 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000009940.3|UniProtKB=G3R378 G3R378 PTHR22237:SF0 APC MEMBRANE RECRUITMENT PROTEIN 2-RELATED APC MEMBRANE RECRUITMENT PROTEIN 1 protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000003608.3|UniProtKB=G3SB06 G3SB06 LOC101137513 PTHR24064:SF592 SOLUTE CARRIER FAMILY 22 MEMBER ORGANIC ANION TRANSPORTER 7 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000004674.3|UniProtKB=G3QPT0 G3QPT0 SLC25A40 PTHR45760:SF5 FI19922P1-RELATED MITOCHONDRIAL GLUTATHIONE TRANSPORTER SLC25A40 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000628.3|UniProtKB=G3RWF1 G3RWF1 ZNF354B PTHR24376:SF210 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 721-RELATED zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000004842.3|UniProtKB=G3QQ83 G3QQ83 CATSPER3 PTHR47131:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215 cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell differentiation#GO:0030154;sperm motility#GO:0097722;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;cilium-dependent cell motility#GO:0060285;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;sperm capacitation#GO:0048240;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;reproductive process#GO:0022414;metal ion transport#GO:0030001;microtubule-based movement#GO:0007018;cell motility#GO:0048870;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;monoatomic cation transport#GO:0006812;localization#GO:0051179;spermatid development#GO:0007286;sexual reproduction#GO:0019953;male gamete generation#GO:0048232;developmental maturation#GO:0021700;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;cell maturation#GO:0048469;transport#GO:0006810;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317 transporter complex#GO:1990351;cation channel complex#GO:0034703;cytoplasm#GO:0005737;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;calcium channel complex#GO:0034704;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000005646.3|UniProtKB=G3RPG0 G3RPG0 SLC1A7 PTHR11958:SF22 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 5 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943 L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;L-glutamate import#GO:0051938;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 GORGO|Ensembl=ENSGGOG00000007637.3|UniProtKB=G3QXC7 G3QXC7 POU2AF2 PTHR28376:SF1 RGD1562914 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;transcription coactivator activity#GO:0003713;DNA binding#GO:0003677 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000043757.1|UniProtKB=A0A2I2YKD7 A0A2I2YKD7 LOC101151974 PTHR19325:SF578 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 RECEPTOR adaptive immune response#GO:0002250;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;regulation of immune effector process#GO:0002697;leukocyte mediated immunity#GO:0002443;T cell mediated immunity#GO:0002456;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 complement component#PC00078;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000043986.1|UniProtKB=A0A2I2YAP6 A0A2I2YAP6 ZNF234 PTHR24381:SF428 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 234 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012184.3|UniProtKB=G3R908 G3R908 C8H10orf71 PTHR33775:SF2 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;heart process#GO:0003015;regulation of biological process#GO:0050789;muscle system process#GO:0003012;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of calcineurin-NFAT signaling cascade#GO:0070884;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;positive regulation of calcium-mediated signaling#GO:0050850;circulatory system process#GO:0003013;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;actin-mediated cell contraction#GO:0070252;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;muscle contraction#GO:0006936;system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle cell contraction#GO:0086003;actin filament-based movement#GO:0030048;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;positive regulation of response to stimulus#GO:0048584 intracellular organelle#GO:0043229;I band#GO:0031674;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000011220.3|UniProtKB=G3R6I4 G3R6I4 CREBRF PTHR21552:SF2 ADULT RETINA PROTEIN CREB3 REGULATORY FACTOR RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000015214.3|UniProtKB=A0A2I2Y2R6 A0A2I2Y2R6 ADGRL1 PTHR23192:SF71 OLFACTOMEDIN-RELATED ADHESION G PROTEIN-COUPLED RECEPTOR L1 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000016456.3|UniProtKB=G3RK14 G3RK14 JAK1 PTHR45807:SF5 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK1 protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;binding#GO:0005488;cytokine receptor binding#GO:0005126;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;interleukin-2-mediated signaling pathway#GO:0038110;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to peptide hormone stimulus#GO:0071375;developmental process#GO:0032502;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;cellular developmental process#GO:0048869;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune response#GO:0006955;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to other organism#GO:0051707;response to peptide hormone#GO:0043434;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;type I interferon-mediated signaling pathway#GO:0060337;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;response to endogenous stimulus#GO:0009719;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;response to stress#GO:0006950;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to type II interferon#GO:0034341;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;interleukin-9-mediated signaling pathway#GO:0038113;interleukin-15-mediated signaling pathway#GO:0035723;cell surface receptor signaling pathway via STAT#GO:0097696 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor tyrosine protein kinase#PC00168 Interferon-gamma signaling pathway#P00035>Jak1#P00953;JAK/STAT signaling pathway#P00038>Jak#P01034;Angiogenesis#P00005>JAK1#P00185;PDGF signaling pathway#P00047>Jak#P01155 GORGO|Ensembl=ENSGGOG00000011942.3|UniProtKB=G3RN97 G3RN97 XYLT2 PTHR46025:SF1 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-xylosyltransferase activity#GO:0035252;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285 proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000007940.3|UniProtKB=G3QY53 G3QY53 XPO5 PTHR11223:SF3 EXPORTIN 1/5 EXPORTIN-5 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013079.3|UniProtKB=G3RBC5 G3RBC5 VAC14 PTHR16023:SF0 TAX1 BINDING PROTEIN-RELATED PROTEIN VAC14 HOMOLOG glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transferase complex#GO:1990234;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025238.2|UniProtKB=G3S9P6 G3S9P6 PTHR11685:SF294 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING RBR-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005794.3|UniProtKB=G3QSM9 G3QSM9 ABHD8 PTHR42886:SF83 RE40534P-RELATED PROTEIN ABHD8 catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;transferase activity#GO:0016740;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;glycerophospholipid biosynthetic process#GO:0046474;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000001905.3|UniProtKB=A0A2I2Y6P8 A0A2I2Y6P8 STK36 PTHR22983:SF7 PROTEIN KINASE RELATED SERINE_THREONINE-PROTEIN KINASE 36 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;smoothened signaling pathway#GO:0007224;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Hedgehog signaling pathway#P00025>Fused#P00686 GORGO|Ensembl=ENSGGOG00000038188.1|UniProtKB=A0A2I2YXJ6 A0A2I2YXJ6 PTHR11592:SF41 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;response to reactive oxygen species#GO:0000302;modified amino acid metabolic process#GO:0006575;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;hydrogen peroxide metabolic process#GO:0042743;cellular response to chemical stimulus#GO:0070887;glutathione metabolic process#GO:0006749;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000026039.2|UniProtKB=G3S8W1 G3S8W1 RPL27 PTHR10497:SF11 60S RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN EL27 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007534.2|UniProtKB=G3QX41 G3QX41 TREM1 PTHR19357:SF0 TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 neutrophil chemotaxis#GO:0030593;immune effector process#GO:0002252;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;granulocyte migration#GO:0097530;neutrophil migration#GO:1990266;taxis#GO:0042330;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;defense response to bacterium#GO:0042742;leukocyte mediated immunity#GO:0002443;leukocyte mediated cytotoxicity#GO:0001909;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;cell killing#GO:0001906;leukocyte migration#GO:0050900;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;cell migration#GO:0016477;response to other organism#GO:0051707;response to bacterium#GO:0009617;chemotaxis#GO:0006935;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000006408.3|UniProtKB=G3RMK8 G3RMK8 CFAP52 PTHR13720:SF14 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000009499.3|UniProtKB=A0A2I2Z430 A0A2I2Z430 SAP30BP PTHR13464:SF0 TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP SAP30-BINDING PROTEIN cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000026358.2|UniProtKB=G3RTC7 G3RTC7 POLR1H PTHR11239:SF14 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428 DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000006399.4|UniProtKB=G3QU64 G3QU64 STX8 PTHR19957:SF285 SYNTAXIN SYNTAXIN-8 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;organelle organization#GO:0006996;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796 SNARE protein#PC00034 GORGO|Ensembl=ENSGGOG00000042442.1|UniProtKB=G3R788 G3R788 RLN3 PTHR20968:SF0 ILGF DOMAIN-CONTAINING PROTEIN RELAXIN-3 molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of response to stimulus#GO:0048584;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of signal transduction#GO:0009967;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000012855.3|UniProtKB=G3RAR7 G3RAR7 ERLIN2 PTHR15351:SF4 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN-2 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;SREBP signaling pathway#GO:0032933;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;signaling#GO:0023052;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 GORGO|Ensembl=ENSGGOG00000025638.2|UniProtKB=G3S3P2 G3S3P2 CHST7 PTHR10704:SF5 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 7 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000005375.3|UniProtKB=G3QRL2 G3QRL2 C13H9orf43 PTHR36130:SF1 RIKEN CDNA 4933430I17 GENE RIKEN CDNA 4933430I17 GENE GORGO|Ensembl=ENSGGOG00000037916.1|UniProtKB=A0A2I2ZCA5 A0A2I2ZCA5 CSDC2 PTHR12962:SF4 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED COLD SHOCK DOMAIN-CONTAINING PROTEIN C2 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of RNA stability#GO:0043487;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA stability#GO:0043488;post-transcriptional regulation of gene expression#GO:0010608;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004569.3|UniProtKB=G3QPI1 G3QPI1 WNT9A PTHR12027:SF75 WNT RELATED PROTEIN WNT-9A signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 GORGO|Ensembl=ENSGGOG00000010028.3|UniProtKB=G3R3G4 G3R3G4 FER PTHR24418:SF227 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FER catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;cellular process#GO:0009987;signal transduction#GO:0007165;taxis#GO:0042330;response to chemical#GO:0042221;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of immune response#GO:0050776;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;chemotaxis#GO:0006935;cell adhesion#GO:0007155;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Fer#P00469 GORGO|Ensembl=ENSGGOG00000003633.3|UniProtKB=G3QM45 G3QM45 PAX5 PTHR45636:SF20 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013074.3|UniProtKB=A0A2I2ZQF8 A0A2I2ZQF8 DCTN6 PTHR13072:SF0 DYNACTIN 6 DYNACTIN SUBUNIT 6 protein-containing complex binding#GO:0044877;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000009689.3|UniProtKB=G3R2L3 G3R2L3 ESCO2 PTHR45884:SF3 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ESCO2 catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080 mitotic sister chromatid cohesion#GO:0007064;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000006436.3|UniProtKB=G3QU95 G3QU95 FHDC1 PTHR45691:SF1 PROTEIN DIAPHANOUS FH2 DOMAIN-CONTAINING PROTEIN 1 protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000007570.3|UniProtKB=A0A2I2Z6M0 A0A2I2Z6M0 PTHR10969:SF110 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GABA TYPE A RECEPTOR ASSOCIATED PROTEIN LIKE 1 ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;GABA receptor binding#GO:0050811;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;signaling receptor binding#GO:0005102 process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;cellular response to nutrient levels#GO:0031669;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular organelle#GO:0043229;autophagosome#GO:0005776;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000024174.2|UniProtKB=G3S9X2 G3S9X2 EXO5 PTHR14464:SF4 EXONUCLEASE V EXONUCLEASE V catalytic activity, acting on DNA#GO:0140097;DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527 response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000040446.1|UniProtKB=A0A2I2Y307 A0A2I2Y307 YPEL PTHR13848:SF1 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 1 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012433.3|UniProtKB=G3R9P1 G3R9P1 WFDC10A PTHR19441:SF38 WAP four-disulfide core domain protein WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 10A enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;response to other organism#GO:0051707;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000016420.3|UniProtKB=G3SGS2 G3SGS2 EBAG9 PTHR15208:SF2 RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS CANCER ASSOCIATED SURFACE ANTIGEN RCAS1 ESTROGEN RECEPTOR-BINDING FRAGMENT- ASSOCIATED GENE 9 PROTEIN RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion#GO:0051046 vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000022175.2|UniProtKB=G3S1J6 G3S1J6 GFRAL PTHR10269:SF1 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;nervous system development#GO:0007399;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001865.3|UniProtKB=G3QHK7 G3QHK7 ERMP1 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000014976.3|UniProtKB=A0A2I2ZNE2 A0A2I2ZNE2 CSAD PTHR45677:SF16 GLUTAMATE DECARBOXYLASE-RELATED CYSTEINE SULFINIC ACID DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;lyase activity#GO:0016829 biosynthetic process#GO:0009058;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 GORGO|Ensembl=ENSGGOG00000027401.2|UniProtKB=G3SEW1 G3SEW1 CEP20 PTHR15431:SF21 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 20 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001886.3|UniProtKB=G3QHM4 G3QHM4 SLC34A3 PTHR10010:SF35 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2C symporter activity#GO:0015293;phosphate transmembrane transporter activity#GO:0005315;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 establishment of localization#GO:0051234;localization#GO:0051179;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;phosphate ion transport#GO:0006817;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;organelle#GO:0043226;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;brush border#GO:0005903;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000012984.3|UniProtKB=A0A2I2ZHI3 A0A2I2ZHI3 AKT1 PTHR24351:SF200 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 response to chemical#GO:0042221;response to stimulus#GO:0050896;response to peptide hormone#GO:0043434;response to nitrogen compound#GO:1901698;response to hormone#GO:0009725;response to endogenous stimulus#GO:0009719;response to oxygen-containing compound#GO:1901700 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>Akt#P00589;Angiogenesis#P00005>Akt#P00223;FGF signaling pathway#P00021>Akt#P00632;Huntington disease#P00029>Akt#P00805;VEGF signaling pathway#P00056>Akt/PKB#P01408;Hypoxia response via HIF activation#P00030>AKT#P00819;EGF receptor signaling pathway#P00018>Akt#P00551;PI3 kinase pathway#P00048>PKB#P01179;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AKT#P00827;p53 pathway#P00059>Akt#P01486;FAS signaling pathway#P00020>ASK1#P00614;p53 pathway by glucose deprivation#P04397>Akt#P04641;T cell activation#P00053>Akt#P01332;p53 pathway feedback loops 2#P04398>AKT#P04665;Interleukin signaling pathway#P00036>PKB#P00973;Ras Pathway#P04393>AKT#P04570;Apoptosis signaling pathway#P00006>AKT#P00260 GORGO|Ensembl=ENSGGOG00000002895.3|UniProtKB=G3QK80 G3QK80 AMZ1 PTHR32205:SF4 ARCHAEMETZINCIN-2-RELATED ARCHAEMETZINCIN-1 GORGO|Ensembl=ENSGGOG00000042536.1|UniProtKB=A0A2I2YB30 A0A2I2YB30 LOC101148826 PTHR13958:SF5 CENTROSOME-ASSOCIATED PROTEIN 350 COILED-COIL DOMAIN-CONTAINING PROTEIN 187 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000012313.3|UniProtKB=G3R9D1 G3R9D1 HIGD1C PTHR12297:SF10 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1C protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009410.3|UniProtKB=G3R1W2 G3R1W2 USE1 PTHR13050:SF10 USE1-LIKE PROTEIN VESICLE TRANSPORT PROTEIN USE1 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000006241.3|UniProtKB=G3QTT0 G3QTT0 CCT2 PTHR11353:SF23 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT BETA macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829;chaperonin-containing T-complex#GO:0005832;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000000748.3|UniProtKB=A0A2I2YK91 A0A2I2YK91 ZFYVE28 PTHR46465:SF3 LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;negative regulation of biological process#GO:0048519;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000004494.3|UniProtKB=G3SCD5 G3SCD5 VASH2 PTHR15750:SF4 VASOHIBIN-1-LIKE ISOFORM X2 TUBULINYL-TYR CARBOXYPEPTIDASE 2 regulation of vasculature development#GO:1901342;regulation of angiogenesis#GO:0045765;regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011681.3|UniProtKB=G3R7Q2 G3R7Q2 PTHR10794:SF45 ABHYDROLASE DOMAIN-CONTAINING PROTEIN MONOACYLGLYCEROL LIPASE ABHD2 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;monocarboxylic acid metabolic process#GO:0032787;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;small molecule catabolic process#GO:0044282;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;fatty acid catabolic process#GO:0009062;signal transduction#GO:0007165;lipid catabolic process#GO:0016042;cellular process#GO:0009987;cellular response to lipid#GO:0071396;cellular response to steroid hormone stimulus#GO:0071383;steroid hormone receptor signaling pathway#GO:0043401;anatomical structure maturation#GO:0071695;cellular response to stimulus#GO:0051716;germ cell development#GO:0007281;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;spermatid development#GO:0007286;response to steroid hormone#GO:0048545;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;biological regulation#GO:0065007;biosynthetic process#GO:0009058;developmental maturation#GO:0021700;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;neutral lipid catabolic process#GO:0046461;fatty acid metabolic process#GO:0006631;acylglycerol metabolic process#GO:0006639;cell maturation#GO:0048469;monocarboxylic acid biosynthetic process#GO:0072330;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;glycerolipid metabolic process#GO:0046486;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;gamete generation#GO:0007276;oxoacid metabolic process#GO:0043436;spermatid differentiation#GO:0048515;glycerolipid catabolic process#GO:0046503;hormone-mediated signaling pathway#GO:0009755;response to hormone#GO:0009725;sperm capacitation#GO:0048240;response to chemical#GO:0042221;response to lipid#GO:0033993;metabolic process#GO:0008152;acylglycerol catabolic process#GO:0046464;carboxylic acid biosynthetic process#GO:0046394;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;catabolic process#GO:0009056;cell communication#GO:0007154;carboxylic acid catabolic process#GO:0046395;fatty acid biosynthetic process#GO:0006633;male gamete generation#GO:0048232;spermatogenesis#GO:0007283;developmental process#GO:0032502;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;neutral lipid metabolic process#GO:0006638;cellular developmental process#GO:0048869 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000036900.1|UniProtKB=A0A2I2Y8L9 A0A2I2Y8L9 C7H8orf82 PTHR31449:SF3 UPF0598 PROTEIN C8ORF82 UPF0598 PROTEIN C8ORF82 GORGO|Ensembl=ENSGGOG00000009775.3|UniProtKB=G3R2T2 G3R2T2 TMEM151A PTHR31893:SF3 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151A intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000000978.3|UniProtKB=G3QFA0 G3QFA0 MED23 PTHR12691:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000006495.3|UniProtKB=G3RTJ6 G3RTJ6 ATP1B4 PTHR11523:SF12 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT PROTEIN ATP1B4 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;regulation of DNA-templated transcription#GO:0006355;monoatomic cation transport#GO:0006812;localization#GO:0051179;potassium ion homeostasis#GO:0055075;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;potassium ion transmembrane transport#GO:0071805;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;regulation of gene expression#GO:0010468;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;import across plasma membrane#GO:0098739;export from cell#GO:0140352;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;import into cell#GO:0098657;chemical homeostasis#GO:0048878 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;organelle inner membrane#GO:0019866;transporter complex#GO:1990351;nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637;organelle membrane#GO:0031090 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000001953.3|UniProtKB=G3QHT5 G3QHT5 GNGT2 PTHR13809:SF28 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-T2 GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117 5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Enkephalin release#P05913>G-Protein (s)#P05977;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;PI3 kinase pathway#P00048>Gbetagamma#P01188;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488 GORGO|Ensembl=ENSGGOG00000023103.2|UniProtKB=G3RSE1 G3RSE1 PTHR43139:SF39 SI:DKEY-122A22.2 AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000038859.1|UniProtKB=A0A2I2ZD55 A0A2I2ZD55 MACROD2 PTHR11106:SF104 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED ADP-RIBOSE GLYCOHYDROLASE MACROD2 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;purine nucleoside metabolic process#GO:0042278;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;carbohydrate derivative metabolic process#GO:1901135;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000038698.1|UniProtKB=A0A2I2YVT4 A0A2I2YVT4 PTHR23232:SF86 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009122.3|UniProtKB=G3R159 G3R159 TYR PTHR11474:SF124 TYROSINASE FAMILY MEMBER TYROSINASE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 biosynthetic process#GO:0009058;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;pigment metabolic process#GO:0042440;phenol-containing compound biosynthetic process#GO:0046189;secondary metabolic process#GO:0019748;melanin biosynthetic process#GO:0042438;pigment biosynthetic process#GO:0046148;secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;melanosome#GO:0042470;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000005569.3|UniProtKB=G3QS30 G3QS30 LOC101152944 PTHR10517:SF15 FOLATE RECEPTOR FOLATE RECEPTOR ALPHA cargo receptor activity#GO:0038024;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705;dicarboxylic acid transport#GO:0006835;vitamin transport#GO:0051180 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000025931.2|UniProtKB=G3S5Y3 G3S5Y3 PTHR11241:SF8 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DUTPASE-LIKE DOMAIN-CONTAINING PROTEIN ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;magnesium ion binding#GO:0000287;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside triphosphate diphosphatase activity#GO:0047429 nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate biosynthetic process#GO:0009124;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000010001.3|UniProtKB=G3R3E2 G3R3E2 FHOD1 PTHR45920:SF2 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FH1_FH2 DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of actin filament-based process#GO:0032970;positive regulation of actin filament bundle assembly#GO:0032233;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;actin filament-based process#GO:0030029;positive regulation of cellular component organization#GO:0051130;supramolecular fiber organization#GO:0097435;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000004595.3|UniProtKB=A0A2I2ZTS9 A0A2I2ZTS9 SNTG1 PTHR10554:SF2 SYNTROPHIN GAMMA-1-SYNTROPHIN membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037093.1|UniProtKB=A0A2I2ZHU9 A0A2I2ZHU9 PTHR23232:SF173 KRAB DOMAIN C2H2 ZINC FINGER RB-ASSOCIATED KRAB ZINC FINGER PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000023015.2|UniProtKB=A0A2I2ZAL3 A0A2I2ZAL3 LOC101124683 PTHR13968:SF3 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS C1_C2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006458.3|UniProtKB=A0A2I2ZKH1 A0A2I2ZKH1 WNK1 PTHR13902:SF46 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK1 molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;protein serine/threonine kinase activity#GO:0004674;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;catalytic activity#GO:0003824;transferase activity#GO:0016740 negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;signaling#GO:0023052;homeostatic process#GO:0042592;negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;chemical homeostasis#GO:0048878 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000006342.3|UniProtKB=A0A2I2YW69 A0A2I2YW69 PITPNC1 PTHR10658:SF55 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CYTOPLASMIC PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1 phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylcholine binding#GO:0031210;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine intramembrane carrier activity#GO:0008525;ion binding#GO:0043167;lipid carrier activity#GO:0005319;anion binding#GO:0043168;small molecule binding#GO:0036094;intramembrane lipid carrier activity#GO:0140303;cation binding#GO:0043169;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;binding#GO:0005488;lipid transfer activity#GO:0120013;lipid binding#GO:0008289 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001985.3|UniProtKB=G3QHW6 G3QHW6 CCDC160 PTHR48251:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 160 COILED-COIL DOMAIN-CONTAINING PROTEIN 160 GORGO|Ensembl=ENSGGOG00000003065.3|UniProtKB=G3QKN4 G3QKN4 TECPR1 PTHR23250:SF16 DYSFERLIN-RELATED TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 1 binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex organization#GO:0043933;process utilizing autophagic mechanism#GO:0061919;metabolic process#GO:0008152;autophagosome maturation#GO:0097352;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;macroautophagy#GO:0016236;cellular component organization#GO:0016043;autophagy#GO:0006914;cellular process#GO:0009987 vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006729.3|UniProtKB=G3QV28 G3QV28 LEMD3 PTHR13428:SF10 INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN INNER NUCLEAR MEMBRANE PROTEIN MAN1 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;membrane assembly#GO:0071709;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;nuclear envelope organization#GO:0006998 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000042370.1|UniProtKB=A0A2I2Y9J9 A0A2I2Y9J9 NKX1-2 PTHR24340:SF17 HOMEOBOX PROTEIN NKX NK1 TRANSCRIPTION FACTOR-RELATED PROTEIN 2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000006499.3|UniProtKB=G3QUF8 G3QUF8 CEP170B PTHR15715:SF18 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA PROTEIN B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;microtubule anchoring#GO:0034453;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005388.3|UniProtKB=A0A2I2YW60 A0A2I2YW60 LOC101132870 PTHR17271:SF9 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN MYOSIN PHOSPHATASE RHO-INTERACTING PROTEIN cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000017027.3|UniProtKB=A0A2I2YTV9 A0A2I2YTV9 CALB2 PTHR19972:SF4 CALBINDIN CALRETININ calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;neuron projection terminus#GO:0044306;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;axon terminus#GO:0043679 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000006388.3|UniProtKB=G3QU57 G3QU57 BRMS1L PTHR21964:SF16 BREAST CANCER METASTASIS-SUPPRESSOR 1 BREAST CANCER METASTASIS-SUPPRESSOR 1-LIKE PROTEIN histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000004102.3|UniProtKB=G3QNB6 G3QNB6 CCDC172 PTHR22419:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 172 COILED-COIL DOMAIN-CONTAINING PROTEIN 172 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Gene=OR1D2|UniProtKB=Q9TU93 Q9TU93 OR1D2 PTHR26453:SF618 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1D2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026811.2|UniProtKB=G3SEF7 G3SEF7 PTHR11528:SF78 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-BETA 2-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;ATP-dependent activity#GO:0140657 gene expression#GO:0010467;protein maturation#GO:0051604;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to stress#GO:0006950;regulation of protein stability#GO:0031647;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein stabilization#GO:0050821;metabolic process#GO:0008152;response to stimulus#GO:0050896;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886 Hsp90 family chaperone#PC00028;chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000022842.2|UniProtKB=G3SAQ8 G3SAQ8 LIPF PTHR11005:SF15 LYSOSOMAL ACID LIPASE-RELATED GASTRIC TRIACYLGLYCEROL LIPASE hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;triacylglycerol lipase activity#GO:0004806;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;lipase#PC00143 GORGO|Ensembl=ENSGGOG00000007096.3|UniProtKB=G3QW01 G3QW01 HYAL2 PTHR11769:SF6 HYALURONIDASE HYALURONIDASE-2 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glycosaminoglycan catabolic process#GO:0006027 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000002807.3|UniProtKB=A0A2I2Z5D0 A0A2I2Z5D0 ZNF135 PTHR24381:SF354 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 135 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Gene=1B01_GORGO|UniProtKB=P30379 P30379 PTHR16675:SF279 MHC CLASS I-RELATED CLASS I HISTOCOMPATIBILITY ANTIGEN, GOGO-B*0102 ALPHA CHAIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823 regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000016976.3|UniProtKB=G3RLC7 G3RLC7 CXXC1 PTHR46174:SF1 CXXC-TYPE ZINC FINGER PROTEIN 1 CXXC-TYPE ZINC FINGER PROTEIN 1 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000000102.3|UniProtKB=A0A2I2Z371 A0A2I2Z371 SIGLEC12 PTHR12035:SF53 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 12 organic acid binding#GO:0043177;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;ion binding#GO:0043167;carbohydrate derivative binding#GO:0097367 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000002424.3|UniProtKB=G3QJ10 G3QJ10 CCAR2 PTHR14304:SF12 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN CELL CYCLE AND APOPTOSIS REGULATOR PROTEIN 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000034878.2|UniProtKB=A0A2I2ZAW1 A0A2I2ZAW1 XPO1 PTHR11223:SF2 EXPORTIN 1/5 EXPORTIN-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;transport#GO:0006810;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit export from nucleus#GO:0000055;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;organelle localization#GO:0051640;ribosome biogenesis#GO:0042254;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002579.3|UniProtKB=G3QJE5 G3QJE5 HDGFL1 PTHR12550:SF85 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR-LIKE PROTEIN 1 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000002402.3|UniProtKB=A0A2I2ZIJ5 A0A2I2ZIJ5 PCYT1B PTHR10739:SF20 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE B lipid binding#GO:0008289;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylcholine binding#GO:0031210;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000002045.3|UniProtKB=G3QI16 G3QI16 FAM162B PTHR13674:SF3 GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN PROTEIN FAM162B GORGO|Ensembl=ENSGGOG00000004375.3|UniProtKB=G3RN39 G3RN39 LRRC18 PTHR45752:SF146 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 18 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000930.3|UniProtKB=G3S1E4 G3S1E4 NUP133 PTHR13405:SF11 NUCLEAR PORE COMPLEX PROTEIN NUP133 NUCLEAR PORE COMPLEX PROTEIN NUP133 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular component organization#GO:0016043;protein import into nucleus#GO:0006606;protein transport#GO:0015031;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405 intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000005453.3|UniProtKB=G3QXA3 G3QXA3 DLGAP4 PTHR12353:SF19 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 4 regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;postsynaptic specialization#GO:0099572;organelle#GO:0043226;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000420.3|UniProtKB=G3QDT6 G3QDT6 TFAP2C PTHR10812:SF9 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2 GAMMA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cell population proliferation#GO:0042127;positive regulation of metabolic process#GO:0009893 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000010154.3|UniProtKB=G3R3S6 G3R3S6 GHRL PTHR14122:SF1 GHRELIN PRECURSOR APPETITE-REGULATING HORMONE protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664 positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;positive regulation of cellular component biogenesis#GO:0044089;regulation of multicellular organismal process#GO:0051239;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of cellular component biogenesis#GO:0044087;positive regulation of cellular component organization#GO:0051130;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;regulation of hormone secretion#GO:0046883;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of synapse assembly#GO:0051963;biological regulation#GO:0065007;positive regulation of developmental process#GO:0051094;regulation of response to stimulus#GO:0048583;positive regulation of synapse assembly#GO:0051965;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;positive regulation of hormone secretion#GO:0046887;regulation of cell junction assembly#GO:1901888;regulation of secretion#GO:0051046;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000004693.3|UniProtKB=G3QPU7 G3QPU7 TAT PTHR45744:SF46 TYROSINE AMINOTRANSFERASE TYROSINE AMINOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039 transaminase#PC00216 Tyrosine biosynthesis#P02784>Aromatic amino acid aminotransferase#P03213 GORGO|Ensembl=ENSGGOG00000002699.3|UniProtKB=A0A2I2Y7F6 A0A2I2Y7F6 RPL5 PTHR23410:SF24 RIBOSOMAL PROTEIN L5-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL18 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;ribosomal large subunit assembly#GO:0000027;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;organelle assembly#GO:0070925;positive regulation of biosynthetic process#GO:0009891;protein-RNA complex assembly#GO:0022618;positive regulation of translation#GO:0045727;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000039473.1|UniProtKB=A0A2I2YUC1 A0A2I2YUC1 DEPDC5 PTHR13179:SF8 DEP DOMAIN CONTAINING PROTEIN 5 GATOR1 COMPLEX PROTEIN DEPDC5 cellular response to amino acid starvation#GO:0034198;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;negative regulation of TORC1 signaling#GO:1904262;response to stimulus#GO:0050896;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Seh1-associated complex#GO:0035859;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000008311.3|UniProtKB=G3QZ23 G3QZ23 COPZ1 PTHR11043:SF2 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA-1 intra-Golgi vesicle-mediated transport#GO:0006891;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000042658.1|UniProtKB=A0A2I2YAG0 A0A2I2YAG0 PTHR12612:SF30 NUCLEAR TRANSPORT FACTOR 2 NTF2 DOMAIN-CONTAINING PROTEIN nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;protein localization to organelle#GO:0033365 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000014655.3|UniProtKB=G3RFD2 G3RFD2 TOX4 PTHR45781:SF2 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 4 chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000008354.3|UniProtKB=G3QZ76 G3QZ76 RALGAPA1 PTHR10063:SF3 TUBERIN RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000006207.3|UniProtKB=G3S7V0 G3S7V0 CLTCL1 PTHR10292:SF6 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN 2 binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810 clathrin-coated vesicle#GO:0030136;clathrin-coated endocytic vesicle#GO:0045334;membrane#GO:0016020;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150;vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 GORGO|Ensembl=ENSGGOG00000040914.1|UniProtKB=A0A2I2Y673 A0A2I2Y673 ZFAND2B PTHR14677:SF13 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 2B metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein targeting to ER#GO:0045047;ubiquitin-dependent protein catabolic process#GO:0006511;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to endoplasmic reticulum#GO:0072599;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;localization#GO:0051179;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein targeting#GO:0006605 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013633.3|UniProtKB=G3RCR4 G3RCR4 CLDN18 PTHR12002:SF9 CLAUDIN CLAUDIN-18 cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330 plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000004391.3|UniProtKB=G3QP32 G3QP32 GCN1 PTHR23346:SF7 TRANSLATIONAL ACTIVATOR GCN1-RELATED STALLED RIBOSOME SENSOR GCN1 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to nutrient levels#GO:0031667;regulation of translation#GO:0006417;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;cellular response to amino acid starvation#GO:0034198;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016736.3|UniProtKB=G3SDX8 G3SDX8 RPL23A PTHR11620:SF60 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005905.3|UniProtKB=G3QSX8 G3QSX8 AQP6 PTHR19139:SF113 AQUAPORIN TRANSPORTER AQUAPORIN-6 transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;nitrate transmembrane transporter activity#GO:0015112;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372 establishment of localization#GO:0051234;localization#GO:0051179;water transport#GO:0006833;fluid transport#GO:0042044;transport#GO:0006810 vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737;apical part of cell#GO:0045177;organelle membrane#GO:0031090;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024756.2|UniProtKB=G3S948 G3S948 CDH19 PTHR24027:SF323 CADHERIN-23 CADHERIN-19 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell migration#GO:0016477;cellular component assembly#GO:0022607;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000001857.3|UniProtKB=G3QHK0 G3QHK0 BTG2 PTHR22978:SF29 B-CELL TRANSLOCATION GENE PROTEIN BTG2 regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;negative regulation of cellular process#GO:0048523;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015713.3|UniProtKB=G3RI43 G3RI43 ACVR2A PTHR23255:SF64 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-2A binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;transferase activity#GO:0016740;kinase activity#GO:0016301;activin binding#GO:0048185;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199 cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;activin receptor signaling pathway#GO:0032924;pattern specification process#GO:0007389;cellular response to growth factor stimulus#GO:0071363;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;signaling receptor complex#GO:0043235;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII/IIB#P06780;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII#P06747 GORGO|Ensembl=ENSGGOG00000015014.3|UniProtKB=A0A2I2Y4X2 A0A2I2Y4X2 PTHR47092:SF1 CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 CHROMATIN REMODELING REGULATOR CECR2 fertilization#GO:0009566;reproductive process#GO:0022414;sexual reproduction#GO:0019953;single fertilization#GO:0007338 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ISWI-type complex#GO:0031010;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785 GORGO|Ensembl=ENSGGOG00000013667.3|UniProtKB=G3RCU8 G3RCU8 LONRF3 PTHR23327:SF41 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000026958.2|UniProtKB=G3RT68 G3RT68 PTHR45696:SF46 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 ribonucleoprotein complex binding#GO:0043021;enzyme regulator activity#GO:0030234;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;binding#GO:0005488;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009479.3|UniProtKB=G3R223 G3R223 CCND2 PTHR10177:SF66 CYCLINS G1_S-SPECIFIC CYCLIN-D2 cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;positive regulation of cellular process#GO:0048522;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 PI3 kinase pathway#P00048>Cyclin d#G01546;Cell cycle#P00013>Cyclin D#P00484 GORGO|Ensembl=ENSGGOG00000002693.3|UniProtKB=A0A2I2YV30 A0A2I2YV30 SCAMP2 PTHR10687:SF7 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 2 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000013923.3|UniProtKB=Q0MQD4 Q0MQD4 NDUFB4 PTHR15469:SF1 NADH-UBIQUINONE OXIDOREDUCTASE B15 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003931.3|UniProtKB=G3QMW4 G3QMW4 ORC1 PTHR10763:SF23 CELL DIVISION CONTROL PROTEIN 6-RELATED ORIGIN RECOGNITION COMPLEX SUBUNIT 1 DNA replication origin binding#GO:0003688;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677 nucleobase-containing compound metabolic process#GO:0006139;DNA replication#GO:0006260;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808;membraneless organelle#GO:0043228;nuclear origin of replication recognition complex#GO:0005664 replication origin binding protein#PC00199 GORGO|Ensembl=ENSGGOG00000005279.3|UniProtKB=G3QRC8 G3QRC8 FRS2 PTHR21258:SF40 DOCKING PROTEIN RELATED FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 2 signaling adaptor activity#GO:0035591;protein binding#GO:0005515;enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;fibroblast growth factor receptor binding#GO:0005104;receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;growth factor receptor binding#GO:0070851 cell surface receptor signaling pathway#GO:0007166;response to fibroblast growth factor#GO:0071774;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794 anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>FRS-2#P00240;FGF signaling pathway#P00021>FRS2#P00635 GORGO|Ensembl=ENSGGOG00000016316.3|UniProtKB=G3RJM0 G3RJM0 DEPDC1 PTHR16206:SF12 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 1A negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Gene=ZFY|UniProtKB=Q52V16 Q52V16 ZFY PTHR24409:SF423 ZINC FINGER PROTEIN 142 ZINC FINGER Y-CHROMOSOMAL PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000037135.1|UniProtKB=A0A2I2YDJ9 A0A2I2YDJ9 VAX1 PTHR24339:SF32 HOMEOBOX PROTEIN EMX-RELATED VENTRAL ANTERIOR HOMEOBOX 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;head development#GO:0060322;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000012864.3|UniProtKB=G3RR66 G3RR66 CD58 PTHR12080:SF150 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cell activation#GO:0001775;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;T cell activation#GO:0042110;biological regulation#GO:0065007;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000024109.2|UniProtKB=A0A2I2ZAH2 A0A2I2ZAH2 PTHR24399:SF62 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER PROTEIN 131 sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007594.3|UniProtKB=G3QX92 G3QX92 MAGOH PTHR12638:SF2 PROTEIN MAGO NASHI HOMOLOG PROTEIN MAGO NASHI HOMOLOG catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;RNA splicing#GO:0008380 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000004872.3|UniProtKB=G3QQB0 G3QQB0 UVSSA PTHR28670:SF1 UV-STIMULATED SCAFFOLD PROTEIN A UV-STIMULATED SCAFFOLD PROTEIN A RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063 cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;response to UV#GO:0009411;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to radiation#GO:0009314;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000016708.3|UniProtKB=G3RKN2 G3RKN2 GALNT8 PTHR11675:SF50 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 8-RELATED polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000003388.3|UniProtKB=G3QLH5 G3QLH5 TMPO PTHR12019:SF24 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN LAMINA-ASSOCIATED POLYPEPTIDE 2, ISOFORM ALPHA intercellular signal molecule#PC00207;peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000043774.1|UniProtKB=A0A2I2ZN94 A0A2I2ZN94 CEP15 PTHR14286:SF2 GENE, 49355-RELATED CENTROSOMAL PROTEIN 15 GORGO|Ensembl=ENSGGOG00000009574.3|UniProtKB=G3R2B7 G3R2B7 PTHR22988:SF33 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE 1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;embryonic morphogenesis#GO:0048598;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;embryo development#GO:0009790;intracellular signaling cassette#GO:0141124;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cytokinesis#GO:0000910;Rho protein signal transduction#GO:0007266;cytoskeleton-dependent cytokinesis#GO:0061640;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;actomyosin structure organization#GO:0031032;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;mitotic cell cycle process#GO:1903047;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;actin filament-based process#GO:0030029;regulation of cell junction assembly#GO:1901888;cortical cytoskeleton organization#GO:0030865;intracellular signal transduction#GO:0035556;anatomical structure development#GO:0048856;cell communication#GO:0007154;cortical actin cytoskeleton organization#GO:0030866;cellular response to stimulus#GO:0051716;cell division#GO:0051301;cell cycle#GO:0007049;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>ROCK#P00881;CCKR signaling map#P06959>ROCK1#P07033 GORGO|Ensembl=ENSGGOG00000008952.3|UniProtKB=G3R0R1 G3R0R1 SFTPD PTHR24024:SF15 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A PULMONARY SURFACTANT-ASSOCIATED PROTEIN D signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of endocytosis#GO:0045807;positive regulation of response to stimulus#GO:0048584;complement activation#GO:0006956;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of cellular component organization#GO:0051130;immune system process#GO:0002376;defense response to other organism#GO:0098542;activation of immune response#GO:0002253;positive regulation of transport#GO:0051050;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;regulation of localization#GO:0032879;regulation of transport#GO:0051049;immune effector process#GO:0002252;regulation of endocytosis#GO:0030100;humoral immune response#GO:0006959 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211;surfactant#PC00212 GORGO|Ensembl=ENSGGOG00000016591.3|UniProtKB=G3SE85 G3SE85 TGFB1 PTHR11848:SF125 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-1 PROPROTEIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to transforming growth factor beta#GO:0071559;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>TGFbeta#P06778;TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000006680.3|UniProtKB=G3QUX4 G3QUX4 PLA2G1B PTHR11716:SF94 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;protein binding#GO:0005515;lipid binding#GO:0008289;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000008034.3|UniProtKB=G3S1P6 G3S1P6 RPL7 PTHR11524:SF12 60S RIBOSOMAL PROTEIN L7 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006391.3|UniProtKB=G3QU52 G3QU52 MRPL41 PTHR21338:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L41 LARGE RIBOSOMAL SUBUNIT PROTEIN ML41 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000016717.3|UniProtKB=G3RKP1 G3RKP1 NCKIPSD PTHR13357:SF1 SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN NCK-INTERACTING PROTEIN WITH SH3 DOMAIN protein-containing complex binding#GO:0044877;binding#GO:0005488 endocytosis#GO:0006897;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006370.3|UniProtKB=G3QU71 G3QU71 WDFY3 PTHR46108:SF1 BLUE CHEESE WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 3 autophagy#GO:0006914;cellular process#GO:0009987;metabolic process#GO:0008152;macroautophagy#GO:0016236;process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056 GORGO|Ensembl=ENSGGOG00000042666.1|UniProtKB=A0A2I2ZLH8 A0A2I2ZLH8 PTHR19433:SF132 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 26-1 response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000025784.2|UniProtKB=G3RPI5 G3RPI5 ZMAT1 PTHR46742:SF2 LYSINE-RICH COILED-COIL PROTEIN 1 ZINC FINGER MATRIN-TYPE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000027303.2|UniProtKB=G3S454 G3S454 ZSWIM1 PTHR31569:SF0 SWIM-TYPE DOMAIN-CONTAINING PROTEIN ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000036256.1|UniProtKB=A0A2I2ZN75 A0A2I2ZN75 FABP9 PTHR11955:SF70 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 9 organic acid binding#GO:0043177;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;lipid binding#GO:0008289;fatty acid binding#GO:0005504 lipid localization#GO:0010876;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;lipid transport#GO:0006869 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000005059.3|UniProtKB=G3QQT3 G3QQT3 GRAMD2A PTHR46973:SF1 GRAM DOMAIN-CONTAINING PROTEIN 2A GRAM DOMAIN-CONTAINING PROTEIN 2A phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546 regulation of biological process#GO:0050789;regulation of calcium ion transport#GO:0051924;regulation of transport#GO:0051049;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle membrane contact site#GO:0044232;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 GORGO|Ensembl=ENSGGOG00000025101.2|UniProtKB=G3SDP2 G3SDP2 DMRT2 PTHR12322:SF122 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;sex differentiation#GO:0007548;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013183.3|UniProtKB=G3RR28 G3RR28 CCDC47 PTHR12883:SF0 ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED PAT COMPLEX SUBUNIT CCDC47 localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;protein folding chaperone complex#GO:0101031;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000038998.1|UniProtKB=A0A2I2ZAL6 A0A2I2ZAL6 TCIM PTHR32358:SF1 TRANSCRIPTIONAL AND IMMUNE RESPONSE REGULATOR TRANSCRIPTIONAL AND IMMUNE RESPONSE REGULATOR protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;cell activation#GO:0001775;regulation of Notch signaling pathway#GO:0008593;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;cell activation involved in immune response#GO:0002263;negative regulation of cell communication#GO:0010648;immune response#GO:0006955;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of Notch signaling pathway#GO:0045746;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000003504.3|UniProtKB=G3QLS9 G3QLS9 TTC9 PTHR11242:SF15 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 9A macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000041718.1|UniProtKB=A0A2I2ZQ65 A0A2I2ZQ65 LOC101138531 PTHR13639:SF2 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000022556.2|UniProtKB=G3RV30 G3RV30 LOC101135462 PTHR22747:SF41 NUCLEOPLASMIN NUCLEOPHOSMIN protein binding#GO:0005515;RNA binding#GO:0003723;histone binding#GO:0042393;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488 chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;regulation of cell cycle#GO:0051726;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;ribosomal large subunit export from nucleus#GO:0000055;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cellular localization#GO:0051641;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;regulation of cell cycle process#GO:0010564;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;nuclear transport#GO:0051169;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000036910.1|UniProtKB=A0A2I2ZSP5 A0A2I2ZSP5 GALNT3 PTHR11675:SF33 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 3 catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000002704.3|UniProtKB=G3QJR3 G3QJR3 VPS51 PTHR15954:SF4 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG Golgi organization#GO:0007030;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000010523.3|UniProtKB=A0A2I2ZET6 A0A2I2ZET6 SERPINB7 PTHR11461:SF56 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B7 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000014420.3|UniProtKB=A0A2I2YQ06 A0A2I2YQ06 PTHR46751:SF7 EPPIN BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;regulation of locomotion#GO:0040012;regulation of reproductive process#GO:2000241;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;negative regulation of cellular process#GO:0048523;regulation of microtubule-based process#GO:0032886 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015952.3|UniProtKB=G3S3N0 G3S3N0 DNAJB13 PTHR24078:SF553 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 13 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Gene=APEX1|UniProtKB=A1YES6 A1YES6 APEX1 PTHR22748:SF6 AP ENDONUCLEASE DNA REPAIR NUCLEASE_REDOX REGULATOR APEX1 3'-5' exonuclease activity#GO:0008408;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;phosphoric ester hydrolase activity#GO:0042578;DNA exonuclease activity#GO:0004529;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;DNA endonuclease activity#GO:0004520;exonuclease activity#GO:0004527;endonuclease activity#GO:0004519;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 GORGO|Ensembl=ENSGGOG00000017148.3|UniProtKB=G3RLS4 G3RLS4 PYCARD PTHR46985:SF2 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;molecular function activator activity#GO:0140677;molecular transducer activity#GO:0060089;enzyme regulator activity#GO:0030234;pattern recognition receptor activity#GO:0038187;peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;signaling receptor activity#GO:0038023 intrinsic apoptotic signaling pathway#GO:0097193;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;inflammatory response#GO:0006954;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of innate immune response#GO:0045088;apoptotic signaling pathway#GO:0097190;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;canonical inflammasome complex#GO:0061702;intracellular organelle#GO:0043229 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000009375.3|UniProtKB=A0A2I2Z191 A0A2I2Z191 SCGB3A1 PTHR34829:SF1 SECRETOGLOBIN FAMILY 3A MEMBER 2 SECRETOGLOBIN FAMILY 3A MEMBER 1 positive regulation of cellular component organization#GO:0051130;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008625.3|UniProtKB=G3RRF4 G3RRF4 AFP PTHR11385:SF7 SERUM ALBUMIN-RELATED ALPHA-FETOPROTEIN binding#GO:0005488;small molecule binding#GO:0036094 response to stimulus#GO:0050896;response to nutrient levels#GO:0031667 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000039127.1|UniProtKB=A0A2I2YKL6 A0A2I2YKL6 PTHR12610:SF32 SINGLE STRANDED DNA BINDING PROTEIN SUBFAMILY NOT NAMED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000014434.3|UniProtKB=G3REV4 G3REV4 PTHR24023:SF1108 COLLAGEN ALPHA EMI DOMAIN CONTAINING 1 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000034847.2|UniProtKB=A0A2I2ZT38 A0A2I2ZT38 TOGARAM1 PTHR21567:SF6 CLASP TOG ARRAY REGULATOR OF AXONEMAL MICROTUBULES PROTEIN 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000008657.3|UniProtKB=G3QZZ1 G3QZZ1 TMEM109 PTHR14550:SF2 TRANSMEMBRANE PROTEIN 109 VOLTAGE-GATED MONOATOMIC CATION CHANNEL TMEM109 DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;cellular response to abiotic stimulus#GO:0071214;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular process#GO:0009987;response to radiation#GO:0009314;signal transduction#GO:0007165;biological regulation#GO:0065007;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;programmed cell death#GO:0012501;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to ionizing radiation#GO:0010212;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;cellular response to radiation#GO:0071478;signaling#GO:0023052 GORGO|Ensembl=ENSGGOG00000008201.3|UniProtKB=G3QYU0 G3QYU0 EP300 PTHR13808:SF29 CBP/P300-RELATED HISTONE ACETYLTRANSFERASE P300 transcription coactivator activity#GO:0003713;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transcription regulator activity#GO:0140110;acetyltransferase activity#GO:0016407;binding#GO:0005488;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;chromatin DNA binding#GO:0031490;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;histone acetyltransferase activity#GO:0004402;DNA binding#GO:0003677;chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228 histone modifying enzyme#PC00261 Wnt signaling pathway#P00057>CBP#P01448;Huntington disease#P00029>CBP#P00777;p53 pathway#P00059>P300#P04611;Gonadotropin-releasing hormone receptor pathway#P06664>p300#P06737;p53 pathway#P00059>CBP#P04623;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Transcription regulation by bZIP transcription factor#P00055>CBP/P300#P01387 GORGO|Ensembl=ENSGGOG00000011445.3|UniProtKB=A0A2I2YFB1 A0A2I2YFB1 BABAM2 PTHR15189:SF8 BRISC AND BRCA1-A COMPLEX MEMBER 2 BRISC AND BRCA1-A COMPLEX MEMBER 2 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001274.3|UniProtKB=G3QG09 G3QG09 SLC16A13 PTHR11360:SF19 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 13 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003261.3|UniProtKB=G3QL63 G3QL63 UBE2K PTHR24068:SF147 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 K acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Ubiquitin proteasome pathway#P00060>E3#P01490 GORGO|Ensembl=ENSGGOG00000039263.1|UniProtKB=G3SCP7 G3SCP7 CRYBB3 PTHR11818:SF13 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B3 structural molecule activity#GO:0005198 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000039806.1|UniProtKB=A0A2I2YBB8 A0A2I2YBB8 RTN4RL1 PTHR24373:SF274 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN RETICULON-4 RECEPTOR-LIKE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000024807.2|UniProtKB=G3RXW9 G3RXW9 EVI2A PTHR15568:SF0 ECOTROPIC VIRAL INTEGRATION SITE 2A PROTEIN EVI2A transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001333.3|UniProtKB=G3QG65 G3QG65 ESRRA PTHR48092:SF15 KNIRPS-RELATED PROTEIN-RELATED STEROID HORMONE RECEPTOR ERR1 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Gonadotropin-releasing hormone receptor pathway#P06664>ER#P06851 GORGO|Ensembl=ENSGGOG00000001335.3|UniProtKB=G3S455 G3S455 EVX2 PTHR46294:SF1 SEGMENTATION PROTEIN EVEN-SKIPPED HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000009306.3|UniProtKB=G3R1M8 G3R1M8 PAM PTHR10680:SF14 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 GORGO|Ensembl=ENSGGOG00000016165.3|UniProtKB=G3RJ90 G3RJ90 LSMEM1 PTHR36475:SF1 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000037002.1|UniProtKB=A0A2I2YT40 A0A2I2YT40 XCL1 PTHR12015:SF101 SMALL INDUCIBLE CYTOKINE A CYTOKINE SCM-1 BETA-RELATED cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 response to peptide#GO:1901652;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;positive regulation of cell motility#GO:2000147;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;taxis#GO:0042330;response to chemical#GO:0042221;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cell motility#GO:2000145;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;cell migration#GO:0016477;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000023746.2|UniProtKB=A0A2I2YN70 A0A2I2YN70 PTHR22747:SF33 NUCLEOPLASMIN NUCLEOPHOSMIN binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;histone binding#GO:0042393;RNA binding#GO:0003723;protein binding#GO:0005515 intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;chromatin organization#GO:0006325;organelle localization#GO:0051640;regulation of microtubule-based process#GO:0032886;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;regulation of DNA-templated transcription#GO:0006355;nuclear transport#GO:0051169;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cell cycle process#GO:0010564;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular localization#GO:0051641;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;ribosomal large subunit export from nucleus#GO:0000055;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;establishment of organelle localization#GO:0051656;regulation of cell cycle#GO:0051726;ribonucleoprotein complex biogenesis#GO:0022613;chromatin remodeling#GO:0006338 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000004930.3|UniProtKB=G3QQG8 G3QQG8 FARP1 PTHR45858:SF2 FERM DOMAIN CONTAINING PROTEIN FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 1 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 GORGO|Ensembl=ENSGGOG00000025155.2|UniProtKB=G3S0R4 G3S0R4 CASP3 PTHR10454:SF198 CASPASE CASPASE-3 molecular function activator activity#GO:0140677;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;enzyme activator activity#GO:0008047;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 skin development#GO:0043588;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;positive regulation of apoptotic process#GO:0043065;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;cell development#GO:0048468;cell differentiation#GO:0030154;positive regulation of programmed cell death#GO:0043068;myeloid cell differentiation#GO:0030099;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;generation of neurons#GO:0048699;proteolysis#GO:0006508;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;hemopoiesis#GO:0030097;biological regulation#GO:0065007;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;positive regulation of cellular process#GO:0048522;multicellular organismal-level homeostasis#GO:0048871;neurogenesis#GO:0022008;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;developmental process#GO:0032502;positive regulation of neuron apoptotic process#GO:0043525;epidermis development#GO:0008544;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;cell death#GO:0008219;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;homeostasis of number of cells#GO:0048872;keratinocyte differentiation#GO:0030216 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 CCKR signaling map#P06959>Pro-caspase-3#P07231;Apoptosis signaling pathway#P00006>Caspase 3#P00305;FAS signaling pathway#P00020>Caspase3#P00599;CCKR signaling map#P06959>Caspase-3#P07108;FAS signaling pathway#P00020>Pro-Caspase3#P00608;Huntington disease#P00029>Caspase 3#P00812 GORGO|Ensembl=ENSGGOG00000024223.2|UniProtKB=G3S9B0 G3S9B0 LY86 PTHR20838:SF0 LYMPHOCYTE ANTIGEN 86 LYMPHOCYTE ANTIGEN 86 innate immune response#GO:0045087;positive regulation of response to external stimulus#GO:0032103;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of cellular process#GO:0048522;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of signaling#GO:0023056;immune system process#GO:0002376;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000012297.3|UniProtKB=G3R9B6 G3R9B6 LOC101135475 PTHR26452:SF974 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5W2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000039878.1|UniProtKB=A0A2I2ZQN0 A0A2I2ZQN0 PTHR19431:SF3 60S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4 C-TERMINAL DOMAIN-CONTAINING PROTEIN structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004954.3|UniProtKB=A0A2I2YR88 A0A2I2YR88 LOC101149662 PTHR23086:SF116 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PIP5K1A AND PSMD4-LIKE PROTEIN-RELATED lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transferase#PC00220;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000003944.3|UniProtKB=G3QMX1 G3QMX1 LOC101152334 PTHR10517:SF17 FOLATE RECEPTOR FOLATE RECEPTOR GAMMA cargo receptor activity#GO:0038024;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;dicarboxylic acid transport#GO:0006835;vitamin transport#GO:0051180;nitrogen compound transport#GO:0071705 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000023693.2|UniProtKB=G3S9G5 G3S9G5 RAB13 PTHR47980:SF42 LD44762P RAS-RELATED PROTEIN RAB-13 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;intracellular transport#GO:0046907;transport#GO:0006810;endocytic recycling#GO:0032456;export from cell#GO:0140352;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;localization within membrane#GO:0051668 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000008208.3|UniProtKB=A0A2I2YTJ7 A0A2I2YTJ7 CD9 PTHR19282:SF163 TETRASPANIN CD9 ANTIGEN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000036874.1|UniProtKB=A0A2I2YD50 A0A2I2YD50 RFLNA PTHR31848:SF0 REFILIN-A-RELATED REFILIN-A animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of multicellular organismal process#GO:0051239;regulation of bone mineralization#GO:0030500;biological regulation#GO:0065007;skeletal system morphogenesis#GO:0048705;regulation of cell development#GO:0060284;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of developmental process#GO:0050793;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000006309.4|UniProtKB=A0A2I2ZUL6 A0A2I2ZUL6 CSMD3 PTHR45656:SF9 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 3 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001602.3|UniProtKB=P61771 P61771 B2M PTHR19944:SF62 MHC CLASS II-RELATED BETA-2-MICROGLOBULIN peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488;protein-containing complex binding#GO:0044877 antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;regulation of immune response#GO:0050776;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of leukocyte activation#GO:0002696;regulation of T cell activation#GO:0050863;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 GORGO|Ensembl=ENSGGOG00000013487.3|UniProtKB=G3RCC6 G3RCC6 PLPPR4 PTHR10165:SF13 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 4 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;lipid modification#GO:0030258;axon development#GO:0061564;organophosphate metabolic process#GO:0019637;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;dephosphorylation#GO:0016311;cellular response to stimulus#GO:0051716;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;metabolic process#GO:0008152;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;phosphate-containing compound metabolic process#GO:0006796;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000006482.3|UniProtKB=G3QUE8 G3QUE8 GRB10 PTHR11243:SF4 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 10 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor complex adaptor activity#GO:0030159 regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;negative regulation of cell communication#GO:0010648;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007109.3|UniProtKB=G3QW12 G3QW12 PFN2 PTHR13936:SF15 PROFILIN PROFILIN-2 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 GORGO|Ensembl=ENSGGOG00000008075.3|UniProtKB=G3QYF7 G3QYF7 TENT5B PTHR12974:SF46 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5B transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 GORGO|Ensembl=ENSGGOG00000039162.1|UniProtKB=A0A2I2Z685 A0A2I2Z685 PTHR12270:SF48 GLYCOSYLTRANSFERASE-RELATED XYLOSYL- AND GLUCURONYLTRANSFERASE LARGE1 pentosyltransferase activity#GO:0016763;glucuronosyltransferase activity#GO:0015020;xylosyltransferase activity#GO:0042285;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000002104.3|UniProtKB=A0A2I2Z6T8 A0A2I2Z6T8 UNC5A PTHR12582:SF4 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5A transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 GORGO|Ensembl=ENSGGOG00000003254.3|UniProtKB=G3QL56 G3QL56 SH2B3 PTHR10872:SF1 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 3 binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971 intracellular signal transduction#GO:0035556;response to peptide#GO:1901652;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;anatomical structure development#GO:0048856;cytokine-mediated signaling pathway#GO:0019221;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;negative regulation of response to cytokine stimulus#GO:0060761;cellular response to chemokine#GO:1990869;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;hemopoiesis#GO:0030097;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;negative regulation of response to stimulus#GO:0048585;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemokine#GO:1990868;regulation of response to cytokine stimulus#GO:0060759 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012922.3|UniProtKB=A0A2I2YEE8 A0A2I2YEE8 DAAM1 PTHR45725:SF16 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1 actomyosin#GO:0042641;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin filament bundle#GO:0032432 GORGO|Ensembl=ENSGGOG00000014650.3|UniProtKB=A0A2I2YL75 A0A2I2YL75 RAB2B PTHR47979:SF50 DRAB11-RELATED RAS-RELATED PROTEIN RAB-2B guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 regulation of secretion#GO:0051046;localization#GO:0051179;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;positive regulation of secretion#GO:0051047;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049;transport#GO:0006810;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;cellular process#GO:0009987 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000022311.2|UniProtKB=A0A2I2YY68 A0A2I2YY68 LOC101128843 PTHR24072:SF379 RHO FAMILY GTPASE CELL DIVISION CONTROL PROTEIN 42 HOMOLOG protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;actin filament organization#GO:0007015;regulation of filopodium assembly#GO:0051489;import into cell#GO:0098657;establishment of localization#GO:0051234;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;regulation of cell projection organization#GO:0031344;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cellular response to stimulus#GO:0051716;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cell projection assembly#GO:0060491;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;localization#GO:0051179;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000042406.1|UniProtKB=G3S8W0 G3S8W0 OR2F1 PTHR26453:SF116 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2F1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000023596.2|UniProtKB=A0A2I2ZJ38 A0A2I2ZJ38 PTHR11581:SF37 30S/40S RIBOSOMAL PROTEIN S4 40S RIBOSOMAL PROTEIN S4 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004712.3|UniProtKB=G3QPV8 G3QPV8 GJB6 PTHR11984:SF23 CONNEXIN GAP JUNCTION BETA-6 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cell communication#GO:0007154;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular process#GO:0009987 cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070;gap junction#PC00105 GORGO|Ensembl=ENSGGOG00000003815.3|UniProtKB=G3QMK8 G3QMK8 DCAF4 PTHR44472:SF3 DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 4 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000000844.3|UniProtKB=G3QEX6 G3QEX6 KCNG1 PTHR11537:SF88 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNG1 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;action potential#GO:0001508;metal ion transport#GO:0030001;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000016538.3|UniProtKB=G3RK72 G3RK72 LOC101133475 PTHR11334:SF59 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER X4 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001398.3|UniProtKB=G3QGC6 G3QGC6 ST8SIA1 PTHR11987:SF3 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-N-ACETYLNEURAMINIDE ALPHA-2,8-SIALYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373 primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;oligosaccharide metabolic process#GO:0009311 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000013458.3|UniProtKB=A0A2I2ZX70 A0A2I2ZX70 CYTH2 PTHR10663:SF343 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875 GORGO|Ensembl=ENSGGOG00000007231.4|UniProtKB=G3QWC3 G3QWC3 DACH2 PTHR12577:SF7 DACHSHUND DACHSHUND HOMOLOG 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000027664.2|UniProtKB=G3RQV1 G3RQV1 SETX PTHR10887:SF552 DNA2/NAM7 HELICASE FAMILY HELICASE SENATAXIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;RNA binding#GO:0003723;double-stranded DNA binding#GO:0003690 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;termination of RNA polymerase II transcription#GO:0006369;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription termination#GO:0006353 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000003132.3|UniProtKB=G3QKU5 G3QKU5 KRT71 PTHR45616:SF16 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 71 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epidermis development#GO:0008544;developmental process#GO:0032502;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000006351.3|UniProtKB=G3QU25 G3QU25 STRADA PTHR48014:SF20 SERINE/THREONINE-PROTEIN KINASE FRAY2 STE20-RELATED KINASE ADAPTER PROTEIN ALPHA kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 protein export from nucleus#GO:0006611;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913 protein-containing complex#GO:0032991;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000023014.2|UniProtKB=G3RN08 G3RN08 CFAP97D1 PTHR33768:SF5 MIP11318P SPERM AXONEMAL MAINTENANCE PROTEIN CFAP97D1 GORGO|Ensembl=ENSGGOG00000007451.3|UniProtKB=A0A2I2Z5T1 A0A2I2Z5T1 PTHR11292:SF7 T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN-RELATED immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000014397.3|UniProtKB=G3REQ4 G3REQ4 PTHR21530:SF7 PHEROMONE SHUTDOWN PROTEIN TRAB DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000026484.2|UniProtKB=G3SHR0 G3SHR0 PTHR10997:SF27 IMPORTIN-7, 8, 11 IMPORTIN-7 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;organelle envelope#GO:0031967;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006672.3|UniProtKB=G3QUW4 G3QUW4 PIGZ PTHR22760:SF3 GLYCOSYLTRANSFERASE GPI ALPHA-1,2-MANNOSYLTRANSFERASE 4 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000009757.3|UniProtKB=G3R2S7 G3R2S7 ALOX12 PTHR11771:SF4 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX12 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824 arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;lipid oxidation#GO:0034440;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;icosanoid metabolic process#GO:0006690;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258 intracellular anatomical structure#GO:0005622;sarcolemma#GO:0042383;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 GORGO|Ensembl=ENSGGOG00000010885.3|UniProtKB=G3R5M7 G3R5M7 CCR3 PTHR10489:SF649 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 3 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930 calcium-mediated signaling#GO:0019722;defense response#GO:0006952;response to external stimulus#GO:0009605;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;locomotion#GO:0040011;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000023964.2|UniProtKB=G3RTU0 G3RTU0 MBOAT7 PTHR13906:SF16 PORCUPINE MEMBRANE-BOUND ACYLGLYCEROPHOSPHATIDYLINOSITOL O-ACYLTRANSFERASE MBOAT7 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid modification#GO:0030258;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 organelle membrane contact site#GO:0044232;membrane#GO:0016020;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;cellular anatomical structure#GO:0110165;organelle#GO:0043226 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000000590.3|UniProtKB=G3QE90 G3QE90 AFG2A PTHR23077:SF27 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000001485.3|UniProtKB=G3QGK8 G3QGK8 PTHR47385:SF20 CALPONIN TRANSGELIN-2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000000725.3|UniProtKB=G3QEL6 G3QEL6 AK7 PTHR23359:SF105 NUCLEOTIDE KINASE ADENYLATE KINASE 7 nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;nucleotide kinase#PC00172 GORGO|Ensembl=ENSGGOG00000043356.1|UniProtKB=G3RBU8 G3RBU8 KRT25 PTHR23239:SF160 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 25 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;skin development#GO:0043588;cytoskeleton organization#GO:0007010;epidermis development#GO:0008544;developmental process#GO:0032502;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009 supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000027957.2|UniProtKB=G3SFD3 G3SFD3 PTGES3 PTHR22932:SF3 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE PROSTAGLANDIN E SYNTHASE 3 protein binding#GO:0005515;binding#GO:0005488;Hsp90 protein binding#GO:0051879;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;protein-folding chaperone binding#GO:0051087;heat shock protein binding#GO:0031072 cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;icosanoid biosynthetic process#GO:0046456;telomere maintenance via telomerase#GO:0007004;telomere maintenance via telomere lengthening#GO:0010833;icosanoid metabolic process#GO:0006690;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;unsaturated fatty acid metabolic process#GO:0033559;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;carboxylic acid metabolic process#GO:0019752;cellular component organization#GO:0016043;monocarboxylic acid metabolic process#GO:0032787;ribonucleoprotein complex biogenesis#GO:0022613;protein folding#GO:0006457;small molecule metabolic process#GO:0044281;nucleic acid biosynthetic process#GO:0141187;oxoacid metabolic process#GO:0043436;macromolecule biosynthetic process#GO:0009059;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;RNA-templated DNA biosynthetic process#GO:0006278;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;monocarboxylic acid biosynthetic process#GO:0072330;macromolecule metabolic process#GO:0043170;carboxylic acid biosynthetic process#GO:0046394;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;chaperone-mediated protein complex assembly#GO:0051131;telomere organization#GO:0032200;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000011393.3|UniProtKB=G3R6Y4 G3R6Y4 RFPL2 PTHR24103:SF657 E3 UBIQUITIN-PROTEIN LIGASE TRIM RET FINGER PROTEIN-LIKE 1-RELATED ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;response to other organism#GO:0051707;defense response to other organism#GO:0098542;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000763.3|UniProtKB=G3QEQ3 G3QEQ3 CXCL17 PTHR37351:SF1 C-X-C MOTIF CHEMOKINE 17 C-X-C MOTIF CHEMOKINE 17 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;leukocyte migration#GO:0050900;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;regulation of biosynthetic process#GO:0009889;leukocyte chemotaxis#GO:0030595;regulation of gene expression#GO:0010468;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;positive regulation of gene expression#GO:0010628;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cell motility#GO:0048870;negative regulation of defense response#GO:0031348;positive regulation of cytokine production#GO:0001819;negative regulation of inflammatory response#GO:0050728;regulation of macromolecule metabolic process#GO:0060255;regulation of leukocyte migration#GO:0002685;locomotion#GO:0040011;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of granulocyte chemotaxis#GO:0071622;chemotaxis#GO:0006935;macrophage chemotaxis#GO:0048246;positive regulation of chemotaxis#GO:0050921;positive regulation of biosynthetic process#GO:0009891;regulation of cell motility#GO:2000145;cell chemotaxis#GO:0060326;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;taxis#GO:0042330;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;positive regulation of response to external stimulus#GO:0032103;regulation of chemotaxis#GO:0050920;negative regulation of biological process#GO:0048519;positive regulation of cell motility#GO:2000147;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;mononuclear cell migration#GO:0071674;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chemokine#PC00074 GORGO|Ensembl=ENSGGOG00000042997.1|UniProtKB=A0A2I2ZQS5 A0A2I2ZQS5 BBIP1 PTHR28596:SF1 BBSOME-INTERACTING PROTEIN 1 BBSOME-INTERACTING PROTEIN 1 organelle assembly#GO:0070925;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;plasma membrane region#GO:0098590;BBSome#GO:0034464;protein-containing complex#GO:0032991;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016966.3|UniProtKB=G3RLB8 G3RLB8 CFAP53 PTHR12396:SF57 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 1 heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of gene expression, epigenetic#GO:0045814;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular component organization or biogenesis#GO:0071840;constitutive heterochromatin formation#GO:0140719 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000026566.2|UniProtKB=G3SBM9 G3SBM9 HOXC11 PTHR46092:SF1 HOMEOBOX PROTEIN HOX-A11-RELATED HOMEOBOX PROTEIN HOX-C11 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;developmental process#GO:0032502;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;skeletal system development#GO:0001501;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000009043.3|UniProtKB=G3R0Z3 G3R0Z3 ECHDC2 PTHR11941:SF44 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000040606.1|UniProtKB=A0A2I2Y902 A0A2I2Y902 ABCB6 PTHR24221:SF664 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 vacuolar membrane#GO:0005774;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000001030.3|UniProtKB=A0A2I2Y5G8 A0A2I2Y5G8 RNF112 PTHR10751:SF1 GUANYLATE BINDING PROTEIN RING FINGER PROTEIN 112 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 heterotrimeric G-protein#PC00117;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000002768.3|UniProtKB=G3QJX1 G3QJX1 MCMDC2 PTHR11630:SF75 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER MINICHROMOSOME MAINTENANCE DOMAIN-CONTAINING PROTEIN 2 macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677 cellular process#GO:0009987;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA replication initiation#GO:0006270;DNA repair#GO:0006281;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;mitotic DNA replication#GO:1902969;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic cell cycle process#GO:1903047;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261 MCM complex#GO:0042555;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000009239.3|UniProtKB=G3SIQ7 G3SIQ7 POLB PTHR11276:SF42 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE BETA DNA-directed DNA polymerase activity#GO:0003887;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 GORGO|Ensembl=ENSGGOG00000008104.3|UniProtKB=G3QYI5 G3QYI5 FOXO1 PTHR45767:SF1 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cellular response to chemical stimulus#GO:0070887;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to insulin stimulus#GO:0032869;regulation of carbohydrate metabolic process#GO:0006109;regulation of carbohydrate biosynthetic process#GO:0043255;cellular response to peptide hormone stimulus#GO:0071375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 CCKR signaling map#P06959>FOXO1#P07167;PI3 kinase pathway#P00048>FOXO#P01198;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>FKHR#P00898 GORGO|Ensembl=ENSGGOG00000009413.3|UniProtKB=G3SEM3 G3SEM3 FOXRED1 PTHR13847:SF294 SARCOSINE DEHYDROGENASE-RELATED FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000011466.3|UniProtKB=G3R751 G3R751 TMEM169 PTHR31777:SF0 TRANSMEMBRANE PROTEIN 169 TRANSMEMBRANE PROTEIN 169 GORGO|Ensembl=ENSGGOG00000042505.1|UniProtKB=A0A2I2YVJ5 A0A2I2YVJ5 PTHR19944:SF91 MHC CLASS II-RELATED IMMUNOGLOBULIN HEAVY CONSTANT EPSILON protein-containing complex binding#GO:0044877;peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 regulation of multicellular organismal process#GO:0051239;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of leukocyte activation#GO:0002696;regulation of lymphocyte activation#GO:0051249;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;immune system process#GO:0002376;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell adhesion#GO:0045785;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;regulation of immune response#GO:0050776 intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000014259.3|UniProtKB=G3REC9 G3REC9 OGG1 PTHR10242:SF2 8-OXOGUANINE DNA GLYCOSYLASE N-GLYCOSYLASE_DNA LYASE catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000022731.2|UniProtKB=G3SJR3 G3SJR3 PTHR13718:SF92 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008797.3|UniProtKB=G3R0B7 G3R0B7 NFATC4 PTHR12533:SF11 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 4 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;calcium-mediated signaling#GO:0019722;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264 Wnt signaling pathway#P00057>NFAT#P01452;B cell activation#P00010>NFAT#P00367;Axon guidance mediated by netrin#P00009>NFAT#P00359;T cell activation#P00053>NFAT#P01294;Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851 GORGO|Ensembl=ENSGGOG00000003252.3|UniProtKB=G3QL50 G3QL50 TPGS1 PTHR31932:SF2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 1 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 1 microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096 multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell projection organization#GO:0030030;sperm motility#GO:0097722;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000016211.3|UniProtKB=G3RJC7 G3RJC7 LOC101134802 PTHR12015:SF98 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 2 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125 response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;response to cytokine#GO:0034097;response to chemical#GO:0042221;taxis#GO:0042330;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;response to stress#GO:0006950;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of locomotion#GO:0040017;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000024546.2|UniProtKB=G3SII0 G3SII0 HCRTR2 PTHR24241:SF75 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OREXIN RECEPTOR TYPE 2 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040274.1|UniProtKB=A0A2I2ZNV7 A0A2I2ZNV7 ANKRD34B PTHR24156:SF1 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34B GORGO|Ensembl=ENSGGOG00000001424.3|UniProtKB=G3QGF4 G3QGF4 STAT6 PTHR11801:SF48 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to peptide hormone stimulus#GO:0071375;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;response to hormone#GO:0009725;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway via STAT#GO:0097696 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832;JAK/STAT signaling pathway#P00038>STAT#P01027 GORGO|Ensembl=ENSGGOG00000000579.4|UniProtKB=G3QE82 G3QE82 KMT2E PTHR46462:SF2 UPSET, ISOFORM A HISTONE READER KMT2E biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;Rpd3L-Expanded complex#GO:0070210;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000039681.1|UniProtKB=A0A2I2YWK9 A0A2I2YWK9 PPIL6 PTHR11071:SF585 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 6-RELATED chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000003830.3|UniProtKB=A0A2I2ZSX5 A0A2I2ZSX5 PROSER1 PTHR14880:SF2 PROLINE AND SERINE-RICH PROTEIN 1 PROLINE AND SERINE-RICH PROTEIN 1 GORGO|Ensembl=ENSGGOG00000024105.2|UniProtKB=G3SJ38 G3SJ38 CDPF1 PTHR31849:SF1 CYSTEINE-RICH PDF MOTIF DOMAIN-CONTAINING PROTEIN 1 CYSTEINE-RICH DPF MOTIF DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000006020.3|UniProtKB=G3QT80 G3QT80 LTB PTHR11471:SF29 TUMOR NECROSIS FACTOR FAMILY MEMBER LYMPHOTOXIN-BETA molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;cell communication#GO:0007154;regulation of apoptotic signaling pathway#GO:2001233 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Apoptosis signaling pathway#P00006>TNF#P00259 GORGO|Ensembl=ENSGGOG00000005284.3|UniProtKB=A0A2I2ZMR8 A0A2I2ZMR8 EIF4H PTHR23236:SF120 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4H RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000005728.3|UniProtKB=G3QSH4 G3QSH4 KIRREL1 PTHR11640:SF14 NEPHRIN KIN OF IRRE-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000010080.3|UniProtKB=G3R3K4 G3R3K4 TAS2R10 PTHR11394:SF63 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 10 molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009980.4|UniProtKB=G3R3B9 G3R3B9 SNTB1 PTHR10554:SF11 SYNTROPHIN BETA-1-SYNTROPHIN cell junction#GO:0030054;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003192.3|UniProtKB=G3QKZ9 G3QKZ9 LIPK PTHR11005:SF45 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER K hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 hydrolase#PC00121;lipase#PC00143 GORGO|Ensembl=ENSGGOG00000022400.2|UniProtKB=G3SGP8 G3SGP8 PTHR20648:SF12 ELONGIN-C ELONGIN-C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000022089.2|UniProtKB=G3RPS0 G3RPS0 PTHR23226:SF85 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 397 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000040886.1|UniProtKB=A0A2I2YSS1 A0A2I2YSS1 PTHR22847:SF677 WD40 REPEAT PROTEIN WDR5-LIKE BETA-PROPELLER DOMAIN-CONTAINING PROTEIN chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 transcription initiation at RNA polymerase II promoter#GO:0006367;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;DNA-templated transcription initiation#GO:0006352;chromatin remodeling#GO:0006338;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;Set1C/COMPASS complex#GO:0048188;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545 GORGO|Ensembl=ENSGGOG00000014656.3|UniProtKB=A0A2I2ZKB3 A0A2I2ZKB3 DCUN1D4 PTHR12281:SF8 RP42 RELATED DCN1-LIKE PROTEIN 4 protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of protein modification process#GO:0031399;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002526.3|UniProtKB=A0A2I2Y8B4 A0A2I2Y8B4 XRCC1 PTHR11370:SF6 DNA-REPAIR PROTEIN XRCC1 DNA REPAIR PROTEIN XRCC1 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000001009.3|UniProtKB=G3QFC5 G3QFC5 CCNI2 PTHR10177:SF57 CYCLINS CYCLIN-I2 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000015558.3|UniProtKB=G3RHQ2 G3RHQ2 MARVELD2 PTHR23288:SF3 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL MARVEL DOMAIN-CONTAINING PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;cell-cell junction assembly#GO:0007043;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;cell-cell junction organization#GO:0045216;transcription by RNA polymerase II#GO:0006366;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;vesicle#GO:0031982;organelle lumen#GO:0043233;intracellular vesicle#GO:0097708;apical plasma membrane#GO:0016324;tight junction#GO:0070160;nuclear protein-containing complex#GO:0140513;cell junction#GO:0030054;apical part of cell#GO:0045177;apical junction complex#GO:0043296;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;bicellular tight junction#GO:0005923;plasma membrane region#GO:0098590;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cell-cell junction#GO:0005911 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000002587.3|UniProtKB=G3QJF4 G3QJF4 ABCD4 PTHR11384:SF59 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER LYSOSOMAL COBALAMIN TRANSPORTER ABCD4 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000011549.3|UniProtKB=G3SDU9 G3SDU9 CALCR PTHR45620:SF8 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;positive regulation of cytosolic calcium ion concentration#GO:0007204;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;axon#GO:0030424 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008835.3|UniProtKB=G3R0F7 G3R0F7 NRDE2 PTHR13471:SF0 TETRATRICOPEPTIDE-LIKE HELICAL NUCLEAR EXOSOME REGULATOR NRDE2 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of RNA metabolic process#GO:0051253;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895 GORGO|Ensembl=ENSGGOG00000016566.3|UniProtKB=G3RK96 G3RK96 USP49 PTHR24006:SF672 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000003827.3|UniProtKB=G3QMM0 G3QMM0 ACADSB PTHR43884:SF1 ACYL-COA DEHYDROGENASE SHORT_BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000001067.3|UniProtKB=G3QFI0 G3QFI0 CHD1L PTHR47157:SF1 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1-LIKE ATP-DEPENDENT CHROMATIN REMODELER CHD1L nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000000103.3|UniProtKB=G3QCZ9 G3QCZ9 TMEM181 PTHR31918:SF2 TRANSMEMBRANE PROTEIN 181 TRANSMEMBRANE PROTEIN 181 regulation of biological process#GO:0050789;regulation of protein secretion#GO:0050708;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of secretion by cell#GO:1903530;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of protein secretion#GO:0050714;regulation of transport#GO:0051049;regulation of localization#GO:0032879 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 GORGO|Ensembl=ENSGGOG00000024657.2|UniProtKB=G3S3Z0 G3S3Z0 LOC101132676 PTHR11346:SF166 GALECTIN GALECTIN-16 binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000013272.3|UniProtKB=G3RBT0 G3RBT0 IL20 PTHR48482:SF2 INTERLEUKIN-19-RELATED INTERLEUKIN-20 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013791.3|UniProtKB=G3RD53 G3RD53 PTHR11394:SF149 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009214.3|UniProtKB=G3R1E4 G3R1E4 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000038956.1|UniProtKB=A0A2I2YJ77 A0A2I2YJ77 PTHR48002:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003051.3|UniProtKB=G3QKM2 G3QKM2 ZMIZ2 PTHR10782:SF38 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 2 transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription coactivator activity#GO:0003713;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;transcription regulator activity#GO:0140110;SUMO ligase activity#GO:0061665;molecular function inhibitor activity#GO:0140678;ubiquitin-like protein ligase activity#GO:0061659 protein sumoylation#GO:0016925;metabolic process#GO:0008152;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;negative regulation of cell communication#GO:0010648;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;protein modification process#GO:0036211 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000022509.2|UniProtKB=A0A2I2ZAP3 A0A2I2ZAP3 PTHR10792:SF32 60S RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN EL24-RELATED N-TERMINAL DOMAIN-CONTAINING PROTEIN cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000038248.1|UniProtKB=A0A2I2YPJ1 A0A2I2YPJ1 SEBOX PTHR47777:SF1 HOMEOBOX PROTEIN SEBOX HOMEOBOX PROTEIN SEBOX helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000003645.3|UniProtKB=A0A2I2YUW8 A0A2I2YUW8 TNS1 PTHR45734:SF3 TENSIN TENSIN-1 cellular process#GO:0009987;cell motility#GO:0048870;cell migration#GO:0016477 anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000012880.3|UniProtKB=Q0MQ86 Q0MQ86 NDUFA12 PTHR12910:SF2 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 12 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000001825.3|UniProtKB=G3QHG8 G3QHG8 CCL17 PTHR12015:SF111 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 17 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000014016.3|UniProtKB=G3RDR0 G3RDR0 ZNF337 PTHR24377:SF218 IP01015P-RELATED ZINC FINGER PROTEIN 182 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009618.3|UniProtKB=A0A2K5TIY2 A0A2K5TIY2 TAS2R3 PTHR11394:SF49 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 3 signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013712.3|UniProtKB=A0A2I2YJ75 A0A2I2YJ75 LRCH4 PTHR45752:SF80 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEATS AND CALPONIN HOMOLOGY (CH) DOMAIN CONTAINING 4 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003304.3|UniProtKB=G3S6R1 G3S6R1 PTHR48615:SF4 LATE CORNIFIED ENVELOPE PROTEIN 1C LATE CORNIFIED ENVELOPE PROTEIN 1D GORGO|Ensembl=ENSGGOG00000016628.3|UniProtKB=G3RKF5 G3RKF5 GAST PTHR19309:SF0 GASTRIN GASTRIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 CCKR signaling map#P06959>G34-Gly#P07036;CCKR signaling map#P06959>G34#P07190;CCKR signaling map#P06959>Beta-arrestin-1/2#P07187;CCKR signaling map#P06959>G17 - Gly#P07236;CCKR signaling map#P06959>G17#P07215 GORGO|Ensembl=ENSGGOG00000014629.3|UniProtKB=G3RFA5 G3RFA5 GPR39 PTHR46752:SF1 G-PROTEIN COUPLED RECEPTOR 39 G PROTEIN-COUPLED RECEPTOR 39 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;biological regulation#GO:0065007;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004640.3|UniProtKB=A0A2I2YLK3 A0A2I2YLK3 PTHR12750:SF11 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 1 phosphotransferase activity, phosphate group as acceptor#GO:0016776;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 nucleotide kinase#PC00172;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000000901.3|UniProtKB=G3QF24 G3QF24 OPALIN PTHR21102:SF0 OPALIN OPALIN cell-cell contact zone#GO:0044291;anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000009926.3|UniProtKB=G3R369 G3R369 DNAAF6 PTHR21083:SF1 TWISTER DYNEIN AXONEMAL ASSEMBLY FACTOR 6 binding#GO:0005488;protein binding#GO:0005515 cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;protein-containing complex assembly#GO:0065003;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;reproductive process#GO:0022414;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;axoneme assembly#GO:0035082;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000002187.3|UniProtKB=G3QIE5 G3QIE5 TCF25 PTHR22684:SF0 NULP1-RELATED RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000026144.2|UniProtKB=G3RW30 G3RW30 LOC101141714 PTHR23105:SF105 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER RIBOSOMAL PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000028322.2|UniProtKB=A0A2I2ZEP9 A0A2I2ZEP9 SLC66A1L PTHR16201:SF42 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED LYSOSOMAL AMINO ACID TRANSPORTER 1 HOMOLOG amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179 L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;homeostatic process#GO:0042592;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;chemical homeostasis#GO:0048878;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;vacuolar transmembrane transport#GO:0034486;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765 GORGO|Ensembl=ENSGGOG00000010583.3|UniProtKB=G3R4V4 G3R4V4 LHX5 PTHR24208:SF115 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008281.3|UniProtKB=A0A2I2ZHH9 A0A2I2ZHH9 MTCH2 PTHR10780:SF20 MITOCHONDRIAL CARRIER HOMOLOG MITOCHONDRIAL CARRIER HOMOLOG 2 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein localization to mitochondrion#GO:0070585;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;positive regulation of cellular process#GO:0048522;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;membrane organization#GO:0061024;regulation of apoptotic process#GO:0042981;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;positive regulation of apoptotic process#GO:0043065;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000016033.3|UniProtKB=G3RUB6 G3RUB6 ANKRD55 PTHR24161:SF129 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED REPEAT PROTEIN, PUTATIVE-RELATED protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000024276.2|UniProtKB=G3S635 G3S635 PTHR14030:SF4 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;sister chromatid cohesion#GO:0007062;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;meiotic sister chromatid cohesion#GO:0051177;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519 membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001476.3|UniProtKB=G3QGK0 G3QGK0 GRAP2 PTHR46037:SF3 PROTEIN ENHANCER OF SEVENLESS 2B GRB2-RELATED ADAPTER PROTEIN 2 protein binding#GO:0005515;growth factor receptor binding#GO:0070851;signaling receptor binding#GO:0005102;binding#GO:0005488 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of MAPK cascade#GO:0043408;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Grb#P00848;PDGF signaling pathway#P00047>Grb2#P01148;T cell activation#P00053>Gads#P01327 GORGO|Ensembl=ENSGGOG00000015618.3|UniProtKB=G3RHV6 G3RHV6 TMEM165 PTHR12608:SF1 TRANSMEMBRANE PROTEIN HTP-1 RELATED DIVALENT CATION_PROTON ANTIPORTER TMEM165-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;homeostatic process#GO:0042592;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000007304.3|UniProtKB=G3S0L6 G3S0L6 CTBP2 PTHR46029:SF3 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 2 transcription coactivator activity#GO:0003713;transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 GORGO|Ensembl=ENSGGOG00000041344.1|UniProtKB=A0A2I2ZX85 A0A2I2ZX85 PTHR45635:SF13 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 3 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000024063.2|UniProtKB=G3S830 G3S830 CBX1 PTHR22812:SF164 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013176.3|UniProtKB=G3RBK1 G3RBK1 GPR108 PTHR21229:SF11 LUNG SEVEN TRANSMEMBRANE RECEPTOR PROTEIN GPR108 negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;negative regulation of cell communication#GO:0010648 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000006100.3|UniProtKB=G3S707 G3S707 ELAVL1 PTHR10352:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 1 regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;positive regulation of biosynthetic process#GO:0009891;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 CCKR signaling map#P06959>HuR#G07273;CCKR signaling map#P06959>HuR#P07211;CCKR signaling map#P06959>HuR#G06980 GORGO|Ensembl=ENSGGOG00000000153.3|UniProtKB=G3QD47 G3QD47 DNAJB14 PTHR43908:SF4 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY B MEMBER 14 heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;cellular response to misfolded protein#GO:0071218;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;primary metabolic process#GO:0044238;response to misfolded protein#GO:0051788;cellular response to stimulus#GO:0051716 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000006518.3|UniProtKB=G3QUH5 G3QUH5 CHAD PTHR45617:SF186 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-RELATED scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000116.3|UniProtKB=G3QD12 G3QD12 EPHX4 PTHR43329:SF2 EPOXIDE HYDROLASE EPOXIDE HYDROLASE 4 catalytic activity#GO:0003824;ether hydrolase activity#GO:0016803;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000014269.3|UniProtKB=A0A2I2YW66 A0A2I2YW66 RAD51 PTHR22942:SF39 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER DNA REPAIR PROTEIN RAD51 HOMOLOG 1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 response to stimulus#GO:0050896;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;double-strand break repair#GO:0006302;protein-containing complex organization#GO:0043933;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;sexual reproduction#GO:0019953;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;DNA repair#GO:0006281;DNA damage response#GO:0006974 membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000011503.3|UniProtKB=G3R783 G3R783 BAG3 PTHR12329:SF12 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 3 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;protein stabilization#GO:0050821;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of protein stability#GO:0031647;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 Apoptosis signaling pathway#P00006>Bag#P00278 GORGO|Ensembl=ENSGGOG00000016786.3|UniProtKB=G3RKU7 G3RKU7 NLRP4 PTHR45690:SF6 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 4 regulation of biological process#GO:0050789;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010947.3|UniProtKB=G3S9R7 G3S9R7 PTHR32546:SF7 G-PROTEIN COUPLED RECEPTOR 158-RELATED G PROTEIN-COUPLED RECEPTOR 179-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000008160.3|UniProtKB=G3QYN7 G3QYN7 ANKRD1 PTHR24126:SF7 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription factor binding#GO:0008134;binding#GO:0005488 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000001643.3|UniProtKB=G3QH02 G3QH02 KLHL5 PTHR24412:SF135 KELCH PROTEIN KELCH-LIKE PROTEIN 5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009558.3|UniProtKB=G3R293 G3R293 IFFO1 PTHR14516:SF2 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER NON-HOMOLOGOUS END JOINING FACTOR IFFO1 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000003393.3|UniProtKB=G3QLI7 G3QLI7 PPEF1 PTHR45668:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 1 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000024124.2|UniProtKB=G3RZ34 G3RZ34 PTHR16471:SF5 CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN-LIKE PROTEIN SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000014439.3|UniProtKB=A0A2I2ZFM3 A0A2I2ZFM3 LZIC PTHR16505:SF8 PROTEIN LZIC PROTEIN LZIC GORGO|Ensembl=ENSGGOG00000004371.3|UniProtKB=G3QP04 G3QP04 PCDH9 PTHR24028:SF248 CADHERIN-87A PROTOCADHERIN-9 cell adhesion#GO:0007155;cellular process#GO:0009987 synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;cell junction#GO:0030054;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000009923.3|UniProtKB=G3RM60 G3RM60 SYNGAP1 PTHR10194:SF25 RAS GTPASE-ACTIVATING PROTEINS RAS_RAP GTPASE-ACTIVATING PROTEIN SYNGAP GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000008510.3|UniProtKB=G3QZK7 G3QZK7 IFNGR1 PTHR20859:SF5 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON GAMMA RECEPTOR 1 cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Interferon-gamma signaling pathway#P00035>IFNGR1#P00959;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866 GORGO|Ensembl=ENSGGOG00000002108.3|UniProtKB=G3QI72 G3QI72 HK3 PTHR19443:SF1 HEXOKINASE HEXOKINASE-3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;hexokinase activity#GO:0004396;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 oxoacid metabolic process#GO:0043436;intracellular glucose homeostasis#GO:0001678;carbohydrate homeostasis#GO:0033500;ribonucleoside diphosphate metabolic process#GO:0009185;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;purine nucleotide catabolic process#GO:0006195;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;nucleotide catabolic process#GO:0009166;intracellular chemical homeostasis#GO:0055082;energy derivation by oxidation of organic compounds#GO:0015980;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;ADP catabolic process#GO:0046032;glucose homeostasis#GO:0042593;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;cellular homeostasis#GO:0019725;ADP metabolic process#GO:0046031;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637 membrane#GO:0016020;cytosol#GO:0005829;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;cytoplasmic side of membrane#GO:0098562;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000008219.3|UniProtKB=A0A2I2YVE6 A0A2I2YVE6 CLCF1 PTHR21353:SF7 FAMILY NOT NAMED CARDIOTROPHIN-LIKE CYTOKINE FACTOR 1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 regulation of lymphocyte proliferation#GO:0050670;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of cellular process#GO:0048522;positive regulation of leukocyte proliferation#GO:0070665;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of B cell proliferation#GO:0030890;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;positive regulation of lymphocyte proliferation#GO:0050671;cell surface receptor signaling pathway via STAT#GO:0097696;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;regulation of B cell activation#GO:0050864;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of B cell proliferation#GO:0030888;positive regulation of leukocyte activation#GO:0002696;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000022764.2|UniProtKB=G3RS88 G3RS88 PTHR12013:SF1 SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN protein targeting#GO:0006605;localization within membrane#GO:0051668;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of protein localization to endoplasmic reticulum#GO:0072599;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;transport#GO:0006810;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012036.3|UniProtKB=G3R8M5 G3R8M5 ZNF205 PTHR23226:SF379 ZINC FINGER AND SCAN DOMAIN-CONTAINING TRANSCRIPTIONAL REPRESSOR RHIT RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014018.3|UniProtKB=G3RDQ9 G3RDQ9 SHH PTHR11889:SF36 HEDGEHOG SONIC HEDGEHOG PROTEIN small molecule binding#GO:0036094;signaling receptor binding#GO:0005102;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169 cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;smoothened signaling pathway#GO:0007224;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502;oligodendrocyte differentiation#GO:0048709;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;central nervous system development#GO:0007417;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;gliogenesis#GO:0042063;cell fate specification#GO:0001708;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Hedgehog signaling pathway#P00025>Hedgehog#P00688 GORGO|Ensembl=ENSGGOG00000014728.3|UniProtKB=G3RFL4 G3RFL4 NFASC PTHR10075:SF113 BASIGIN RELATED NEUROFASCIN cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000008700.3|UniProtKB=G3R031 G3R031 RNF144B PTHR11685:SF104 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144B catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000009480.3|UniProtKB=G3R225 G3R225 STX10 PTHR19957:SF106 SYNTAXIN SYNTAXIN-10 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cytosolic transport#GO:0016482;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 synapse#GO:0045202;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;presynapse#GO:0098793;cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 SNARE protein#PC00034 Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074 GORGO|Ensembl=ENSGGOG00000003439.3|UniProtKB=G3QLM3 G3QLM3 TRIM67 PTHR24099:SF21 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 67 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000015587.3|UniProtKB=A0A2I2ZXA9 A0A2I2ZXA9 ADGRB3 PTHR12011:SF40 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR B3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;cell maturation#GO:0048469;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell development#GO:0048468;anatomical structure maturation#GO:0071695;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 extracellular region#GO:0005576;cell junction#GO:0030054;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 p53 pathway#P00059>BAI-1#G04699 GORGO|Ensembl=ENSGGOG00000040919.1|UniProtKB=A0A2I2YJH6 A0A2I2YJH6 H1-1 PTHR11467:SF176 HISTONE H1 HISTONE H1.1 protein-containing complex binding#GO:0044877;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;DNA binding#GO:0003677;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin DNA binding#GO:0031490 biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000002858.3|UniProtKB=G3RNC5 G3RNC5 LTO1 PTHR28532:SF1 GEO13458P1 LTO1 MATURATION FACTOR OF ABCE1 GORGO|Ensembl=ENSGGOG00000007216.3|UniProtKB=G3S6X7 G3S6X7 BTAF1 PTHR36498:SF1 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 GORGO|Ensembl=ENSGGOG00000005657.3|UniProtKB=G3QSA7 G3QSA7 CCDC167 PTHR31759:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 167 COILED-COIL DOMAIN-CONTAINING PROTEIN 167 GORGO|Ensembl=ENSGGOG00000003331.3|UniProtKB=G3QLC5 G3QLC5 GDAP1L1 PTHR44188:SF2 GDAP1, ISOFORM A GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 1-LIKE 1 cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;cellular process#GO:0009987;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266;organelle fusion#GO:0048284 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867 GORGO|Ensembl=ENSGGOG00000015446.3|UniProtKB=G3RHE5 G3RHE5 TAS2R41 PTHR11394:SF73 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 41 taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of taste#GO:0050909;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010141.3|UniProtKB=G3RTG9 G3RTG9 AP2A1 PTHR22780:SF33 ADAPTIN, ALPHA/GAMMA/EPSILON AP-2 COMPLEX SUBUNIT ALPHA-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898 coated vesicle#GO:0030135;endocytic vesicle#GO:0030139;coated membrane#GO:0048475;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506 membrane traffic protein#PC00150 Huntington disease#P00029>alpha-Adaptin#P00782 GORGO|Ensembl=ENSGGOG00000003446.3|UniProtKB=A0A2I2Z8F8 A0A2I2Z8F8 CLASP2 PTHR21567:SF30 CLASP CLIP-ASSOCIATING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 mitotic sister chromatid segregation#GO:0000070;establishment of spindle localization#GO:0051293;mitotic spindle assembly#GO:0090307;spindle organization#GO:0007051;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;localization#GO:0051179;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;organelle localization#GO:0051640;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059;establishment of organelle localization#GO:0051656;mitotic spindle organization#GO:0007052;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;spindle localization#GO:0051653;cellular localization#GO:0051641;nuclear division#GO:0000280 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;microtubule organizing center#GO:0005815;spindle#GO:0005819;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitotic spindle#GO:0072686;chromosome#GO:0005694;cytoplasmic microtubule#GO:0005881;basal part of cell#GO:0045178;cell cortex#GO:0005938;kinetochore#GO:0000776;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000004223.3|UniProtKB=G3QNM7 G3QNM7 RTF2 PTHR12775:SF0 PROTEIN C20ORF43 HOMOLOG REPLICATION TERMINATION FACTOR 2 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000005715.3|UniProtKB=A0A2I2YIK2 A0A2I2YIK2 ABI3BP PTHR23197:SF10 TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING TARGET OF NESH-SH3 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cellular process#GO:0009987;cell differentiation#GO:0030154;tissue development#GO:0009888;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;mesenchymal cell differentiation#GO:0048762;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;animal organ development#GO:0048513;mesenchyme development#GO:0060485 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002009.3|UniProtKB=G3S662 G3S662 APOL2 PTHR14096:SF27 APOLIPOPROTEIN L APOLIPOPROTEIN L2 lipid binding#GO:0008289;binding#GO:0005488 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000012809.3|UniProtKB=G3RAM2 G3RAM2 BICRA PTHR15572:SF1 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013283.3|UniProtKB=G3S6R3 G3S6R3 ZNF679 PTHR24393:SF187 ZINC FINGER PROTEIN ZINC FINGER PROTEIN binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000008531.3|UniProtKB=G3QZM7 G3QZM7 PINX1 PTHR23149:SF27 G PATCH DOMAIN CONTAINING PROTEIN PIN2_TERF1-INTERACTING TELOMERASE INHIBITOR 1 enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010626.3|UniProtKB=G3R4Z5 G3R4Z5 POGLUT3 PTHR12203:SF18 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 3 glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008266.3|UniProtKB=A0A2I2YD72 A0A2I2YD72 OSBPL6 PTHR10972:SF76 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 6 sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094;cholesterol binding#GO:0015485;steroid binding#GO:0005496;lipid binding#GO:0008289;alcohol binding#GO:0043178 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;plasma membrane#GO:0005886;nuclear envelope#GO:0005635;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000014350.3|UniProtKB=G3REL4 G3REL4 ALOX15B PTHR11771:SF207 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX15B oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;arachidonate metabolic process#GO:0019369;carboxylic acid biosynthetic process#GO:0046394;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid modification#GO:0030258;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005797.3|UniProtKB=G3QSN1 G3QSN1 EVA1C PTHR46780:SF4 PROTEIN EVA-1 PROTEIN EVA-1 HOMOLOG C heparin binding#GO:0008201;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000043207.1|UniProtKB=A0A2I2ZDG8 A0A2I2ZDG8 SMAD3 PTHR13703:SF53 SMAD SMAD FAMILY MEMBER 3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 response to transforming growth factor beta#GO:0071559;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;BMP signaling pathway#GO:0030509;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;activin receptor signaling pathway#GO:0032924;cellular response to growth factor stimulus#GO:0071363;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;transforming growth factor beta receptor signaling pathway#GO:0007179;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule metabolic process#GO:0010604;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 GORGO|Ensembl=ENSGGOG00000004692.3|UniProtKB=G3QPU3 G3QPU3 TRIM75 PTHR24103:SF312 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 75 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009933.3|UniProtKB=G3R377 G3R377 NUDCD2 PTHR12356:SF18 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 2 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000023541.2|UniProtKB=G3S8N3 G3S8N3 ANKRD45 PTHR24180:SF14 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 45 cellular process#GO:0009987;cell population proliferation#GO:0008283 midbody#GO:0030496;cellular anatomical structure#GO:0110165 kinase inhibitor#PC00139;kinase modulator#PC00140 GORGO|Gene=CFTR|UniProtKB=Q2IBF6 Q2IBF6 CFTR PTHR24223:SF19 ATP-BINDING CASSETTE SUB-FAMILY C CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR transmembrane transporter activity#GO:0022857;macromolecular conformation isomerase activity#GO:0120543;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;catalytic activity#GO:0003824;isomerase activity#GO:0016853;ligand-gated monoatomic ion channel activity#GO:0015276;polypeptide conformation or assembly isomerase activity#GO:0120544;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;water transport#GO:0006833;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;fluid transport#GO:0042044;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;cytosol#GO:0005829;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000017179.3|UniProtKB=G3RLV4 G3RLV4 POPDC3 PTHR12101:SF18 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 3 ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 biological regulation#GO:0065007;heart development#GO:0007507;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;striated muscle cell differentiation#GO:0051146;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;developmental process#GO:0032502;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;system development#GO:0048731;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;sarcolemma#GO:0042383;apical junction complex#GO:0043296 GORGO|Ensembl=ENSGGOG00000014995.3|UniProtKB=G3RG94 G3RG94 GNA11 PTHR10218:SF328 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-11 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212;regulation of membrane potential#GO:0042391;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;action potential#GO:0001508;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;regulation of biological quality#GO:0065008;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234 G-protein#PC00020;heterotrimeric G-protein#PC00117 Wnt signaling pathway#P00057>Galpha#P01451;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Gonadotropin-releasing hormone receptor pathway#P06664>gnaq/11#P06841;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Endothelin signaling pathway#P00019>Gq#P00586;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Alpha adrenergic receptor signaling pathway#P00002>G-Protein#P00077 GORGO|Ensembl=ENSGGOG00000042692.1|UniProtKB=A0A2I2ZN71 A0A2I2ZN71 PTHR24299:SF11 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1B1 oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 catabolic process#GO:0009056;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;estrogen metabolic process#GO:0008210;steroid catabolic process#GO:0006706;regulation of biological quality#GO:0065008;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;hormone metabolic process#GO:0042445;response to chemical#GO:0042221;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;cellular response to xenobiotic stimulus#GO:0071466;lipid catabolic process#GO:0016042;cellular process#GO:0009987;secondary metabolic process#GO:0019748;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010158.3|UniProtKB=G3SAN9 G3SAN9 SEC13 PTHR11024:SF21 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER PROTEIN SEC13 HOMOLOG regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;protein transport#GO:0015031;protein import into nucleus#GO:0006606;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;organelle organization#GO:0006996;vesicle-mediated transport#GO:0016192;COPII-coated vesicle budding#GO:0090114;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;positive regulation of TOR signaling#GO:0032008;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;vesicle budding from membrane#GO:0006900;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;membrane organization#GO:0061024;positive regulation of response to stimulus#GO:0048584 intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;coated membrane#GO:0048475;nuclear envelope#GO:0005635;vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;nuclear pore#GO:0005643;bounding membrane of organelle#GO:0098588;nuclear protein-containing complex#GO:0140513;vesicle#GO:0031982;nuclear pore outer ring#GO:0031080;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;ER to Golgi transport vesicle membrane#GO:0012507;organelle membrane#GO:0031090 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000009144.3|UniProtKB=G3R184 G3R184 TBX2 PTHR11267:SF82 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 GORGO|Ensembl=ENSGGOG00000000270.3|UniProtKB=A0A2I2ZMQ5 A0A2I2ZMQ5 HORMAD2 PTHR48225:SF6 HORMA DOMAIN-CONTAINING PROTEIN 1 HORMA DOMAIN-CONTAINING PROTEIN 2 nuclear division#GO:0000280;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;homologous chromosome segregation#GO:0045143;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;regulation of cell cycle process#GO:0010564;homologous chromosome pairing at meiosis#GO:0007129;cellular component assembly#GO:0022607;synaptonemal complex assembly#GO:0007130;cell cycle checkpoint signaling#GO:0000075;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of reproductive process#GO:2000241 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;synaptonemal structure#GO:0099086;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793 GORGO|Ensembl=ENSGGOG00000003135.3|UniProtKB=G3QKU8 G3QKU8 EPX PTHR11475:SF145 OXIDASE/PEROXIDASE EOSINOPHIL PEROXIDASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012327.3|UniProtKB=G3R9E7 G3R9E7 ADCK2 PTHR45890:SF26 AARF DOMAIN CONTAINING KINASE 2 (PREDICTED) NADH:UBIQUINONE OXIDOREDUCTASE SUBUNIT B2 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003986.3|UniProtKB=G3QN08 G3QN08 SLC16A12 PTHR11360:SF318 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 12 monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000000941.3|UniProtKB=G3RM43 G3RM43 DNAAF1 PTHR45973:SF19 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN AXONEMAL ASSEMBLY FACTOR 1 binding#GO:0005488;protein-containing complex binding#GO:0044877 left/right pattern formation#GO:0060972;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;specification of symmetry#GO:0009799;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;determination of bilateral symmetry#GO:0009855;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;regionalization#GO:0003002;cellular component assembly#GO:0022607;microtubule bundle formation#GO:0001578;pattern specification process#GO:0007389;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;determination of left/right symmetry#GO:0007368;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030 intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000009221.3|UniProtKB=G3R1F0 G3R1F0 GMEB1 PTHR10417:SF3 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000024230.2|UniProtKB=G3SGJ2 G3SGJ2 PTHR12406:SF4 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 5 transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;triacylglycerol lipase activity#GO:0004806;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;cellular process#GO:0009987;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid catabolic process#GO:0046461;chemical homeostasis#GO:0048878;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;homeostatic process#GO:0042592;triglyceride catabolic process#GO:0019433;glycerolipid catabolic process#GO:0046503 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000016707.3|UniProtKB=A0A2I2Y9Y6 A0A2I2Y9Y6 KTN1 PTHR18864:SF1 KINECTIN KINECTIN GORGO|Ensembl=ENSGGOG00000004126.3|UniProtKB=G3QND7 G3QND7 LOC101141762 PTHR48068:SF3 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 9 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 chromatin#GO:0000785;SAGA complex#GO:0000124;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;acetyltransferase complex#GO:1902493;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;peptidase complex#GO:1905368;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 GORGO|Ensembl=ENSGGOG00000007501.3|UniProtKB=G3QX10 G3QX10 PRDM8 PTHR16516:SF7 AGAP007109-PA PR DOMAIN ZINC FINGER PROTEIN 8 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000009270.3|UniProtKB=G3R1I4 G3R1I4 DEGS1 PTHR12879:SF2 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE DES1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 oxidoreductase#PC00176;hydroxylase#PC00122 GORGO|Ensembl=ENSGGOG00000024924.2|UniProtKB=G3S683 G3S683 PDRG1 PTHR21162:SF0 P53 AND DNA DAMAGE-REGULATED PROTEIN P53 AND DNA DAMAGE-REGULATED PROTEIN 1 GORGO|Ensembl=ENSGGOG00000040557.1|UniProtKB=A0A2I2ZCA8 A0A2I2ZCA8 CHAF1A PTHR15272:SF0 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008469.3|UniProtKB=G3QZH1 G3QZH1 LRRC36 PTHR23311:SF6 HEAT SHOCK REGULATED 2 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 36 GORGO|Ensembl=ENSGGOG00000013686.3|UniProtKB=G3RCW5 G3RCW5 CATSPER1 PTHR47193:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1 channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;calcium ion transport#GO:0006816;microtubule-based process#GO:0007017;regulation of biological process#GO:0050789;sperm motility#GO:0097722;regulation of microtubule-based movement#GO:0060632;gamete generation#GO:0007276;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;male gamete generation#GO:0048232;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;transport#GO:0006810;establishment of localization#GO:0051234;developmental process involved in reproduction#GO:0003006;cell motility#GO:0048870;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;metal ion transport#GO:0030001;reproductive process#GO:0022414;regulation of microtubule-based process#GO:0032886;sexual reproduction#GO:0019953;localization#GO:0051179;regulation of cell motility#GO:2000145;monoatomic cation transport#GO:0006812;multicellular organismal reproductive process#GO:0048609 monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000025204.2|UniProtKB=G3S285 G3S285 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000026746.2|UniProtKB=G3S6H6 G3S6H6 DSE PTHR15532:SF3 FAMILY NOT NAMED DERMATAN-SULFATE EPIMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854 chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000013652.3|UniProtKB=G3RCT4 G3RCT4 IFI44L PTHR14241:SF2 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-LIKE response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 GORGO|Ensembl=ENSGGOG00000005325.3|UniProtKB=G3QRG6 G3QRG6 SUPV3L1 PTHR12131:SF31 ATP-DEPENDENT RNA AND DNA HELICASE ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000001480.3|UniProtKB=G3QGK2 G3QGK2 UBE2U PTHR24067:SF252 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 U ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000025704.2|UniProtKB=A0A2I2ZQ58 A0A2I2ZQ58 PTHR10809:SF100 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN MSP DOMAIN-CONTAINING PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 endomembrane system organization#GO:0010256;membrane organization#GO:0061024;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;endoplasmic reticulum membrane organization#GO:0090158;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000023363.2|UniProtKB=A0A2I2YYR6 A0A2I2YYR6 C12H2orf49 PTHR28359:SF1 ASHWIN TRNA-SPLICING LIGASE COMPLEX SUBUNIT ASW cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000000756.3|UniProtKB=G3QEP6 G3QEP6 LOC101129337 PTHR11407:SF62 LYSOZYME C LYSOZYME-LIKE PROTEIN 1-RELATED hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;lysozyme activity#GO:0003796;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000000306.3|UniProtKB=G3QDI4 G3QDI4 STAM PTHR45929:SF2 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE SIGNAL TRANSDUCING ADAPTER MOLECULE 1 endosomal transport#GO:0016197;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein transport#GO:0015031;cellular localization#GO:0051641;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization to vacuole#GO:0072666;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;macromolecule localization#GO:0033036;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009825.3|UniProtKB=G3R2Y3 G3R2Y3 GAL3ST1 PTHR14647:SF56 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid biosynthetic process#GO:0008610;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;developmental process#GO:0032502;ceramide biosynthetic process#GO:0046513;carbohydrate derivative biosynthetic process#GO:1901137;multicellular organism development#GO:0007275;myelination#GO:0042552;primary metabolic process#GO:0044238;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;animal gross anatomical part developmental process#GO:0160108;glycosphingolipid biosynthetic process#GO:0006688;ceramide metabolic process#GO:0006672;anatomical structure development#GO:0048856;glycolipid biosynthetic process#GO:0009247;system development#GO:0048731 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009374.3|UniProtKB=G3R1T1 G3R1T1 ARHGDIB PTHR10980:SF15 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 2 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000006317.3|UniProtKB=G3RV77 G3RV77 AUP1 PTHR15486:SF103 ANCIENT UBIQUITOUS PROTEIN LIPID DROPLET-REGULATING VLDL ASSEMBLY FACTOR AUP1 protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004778.3|UniProtKB=G3QQ30 G3QQ30 PELP1 PTHR34105:SF1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002617.3|UniProtKB=A0A2I2Z6S1 A0A2I2Z6S1 SPAG6 PTHR23314:SF3 SPERM-ASSOCIATED ANTIGEN 6 ARMADILLO REPEAT-CONTAINING SPERM-ASSOCIATED ANTIGEN 6 cilium movement#GO:0003341;cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;sperm principal piece#GO:0097228;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000039276.1|UniProtKB=A0A2I2YKS8 A0A2I2YKS8 ZNF283 PTHR24377:SF63 IP01015P-RELATED ZINC FINGER PROTEIN 283 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011538.3|UniProtKB=G3R7C1 G3R7C1 PECAM1 PTHR11481:SF5 IMMUNOGLOBULIN FC RECEPTOR PLATELET ENDOTHELIAL CELL ADHESION MOLECULE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell-cell adhesion#GO:0098609;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell communication#GO:0007154 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000004309.3|UniProtKB=A0A2I2ZGI0 A0A2I2ZGI0 TNFRSF11A PTHR47134:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11A TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11A death receptor activity#GO:0005035;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to peptide#GO:1901652;regulation of bone resorption#GO:0045124;cell development#GO:0048468;signaling#GO:0023052;myeloid cell differentiation#GO:0030099;response to stimulus#GO:0050896;cell differentiation#GO:0030154;positive regulation of multicellular organismal process#GO:0051240;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;leukocyte differentiation#GO:0002521;cellular developmental process#GO:0048869;developmental process#GO:0032502;hemopoiesis#GO:0030097;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to tumor necrosis factor#GO:0034612;regulation of bone remodeling#GO:0046850;regulation of tissue remodeling#GO:0034103;osteoclast differentiation#GO:0030316;anatomical structure development#GO:0048856;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;ossification#GO:0001503;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007364.3|UniProtKB=G3RZZ7 G3RZZ7 KCNQ4 PTHR47735:SF7 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 cellular process#GO:0009987;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 voltage-gated ion channel#PC00241;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000022087.2|UniProtKB=G3S2Z6 G3S2Z6 PTHR12538:SF7 40S RIBOSOMAL PROTEIN S26 SMALL RIBOSOMAL SUBUNIT PROTEIN ES26-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000001261.3|UniProtKB=G3QFZ9 G3QFZ9 HLTF PTHR45626:SF17 TRANSCRIPTION TERMINATION FACTOR 2-RELATED DNA-DEPENDENT ATPASE_E3 UBIQUITIN-PROTEIN LIGASE HLTF ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000011434.3|UniProtKB=G3R721 G3R721 PTHR24369:SF161 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 53 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000026674.2|UniProtKB=G3RNT3 G3RNT3 LOC101146492 PTHR11760:SF34 30S/40S RIBOSOMAL PROTEIN S3 SMALL RIBOSOMAL SUBUNIT PROTEIN US3 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosol#GO:0005829;nucleus#GO:0005634;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000040906.1|UniProtKB=A0A2I2YNZ4 A0A2I2YNZ4 FKBP11 PTHR45779:SF2 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP11 catalytic activity#GO:0003824;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000012405.3|UniProtKB=A0A2I2YKH7 A0A2I2YKH7 CLSTN1 PTHR14139:SF4 CALSYNTENIN CALSYNTENIN-1 protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;positive regulation of synapse assembly#GO:0051965;positive regulation of developmental process#GO:0051094;regulation of synapse assembly#GO:0051963;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 cell junction#GO:0030054;synaptic membrane#GO:0097060;neuron to neuron synapse#GO:0098984;cell surface#GO:0009986;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000008346.3|UniProtKB=G3S8D7 G3S8D7 NKAIN4 PTHR13084:SF5 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 4 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000036914.1|UniProtKB=A0A2I2ZF28 A0A2I2ZF28 BOK PTHR11256:SF48 BCL-2 RELATED BCL-2-RELATED OVARIAN KILLER PROTEIN channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;signaling#GO:0023052;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;organelle organization#GO:0006996;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Bok#P00261 GORGO|Ensembl=ENSGGOG00000026286.2|UniProtKB=G3SC32 G3SC32 VRK3 PTHR11909:SF99 CASEIN KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE VRK3 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;response to stress#GO:0006950;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000016490.3|UniProtKB=G3RK31 G3RK31 TMEM176B PTHR15756:SF7 LR8/HCA112 TRANSMEMBRANE PROTEIN 176B regulation of hemopoiesis#GO:1903706;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell development#GO:0060284;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241 GORGO|Ensembl=ENSGGOG00000016853.3|UniProtKB=A0A2I2ZJV3 A0A2I2ZJV3 PTHR16166:SF125 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13C transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014 transport#GO:0006810;metabolic process#GO:0008152;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagy#GO:0006914;macromolecule localization#GO:0033036;organelle organization#GO:0006996;macroautophagy#GO:0016236;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;lipid transport#GO:0006869;lipid localization#GO:0010876;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;cellular component organization#GO:0016043;catabolic process#GO:0009056 endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;vesicle#GO:0031982;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;outer membrane#GO:0019867;endosome#GO:0005768 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011406.3|UniProtKB=A0A2I2Y5G9 A0A2I2Y5G9 KCNQ5 PTHR47735:SF8 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 5 voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 transporter#PC00227;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000002493.3|UniProtKB=G3QJ73 G3QJ73 CHRDL1 PTHR46303:SF2 VWFC DOMAIN-CONTAINING PROTEIN CHORDIN-LIKE PROTEIN 1 binding#GO:0005488;cytokine binding#GO:0019955;protein binding#GO:0005515 negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000001597.3|UniProtKB=G3QGW7 G3QGW7 KALRN PTHR22826:SF49 RHO GUANINE EXCHANGE FACTOR-RELATED KALIRIN molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;intracellular signal transduction#GO:0035556;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;membrane#GO:0016020;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;postsynaptic density#GO:0014069 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 Huntington disease#P00029>Duo#P00773 GORGO|Ensembl=ENSGGOG00000014980.3|UniProtKB=A0A2I2Z9D4 A0A2I2Z9D4 NT5C1B PTHR31367:SF0 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1B catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside metabolic process#GO:0042278;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000007053.3|UniProtKB=G3SES4 G3SES4 SEMA3B PTHR11036:SF37 SEMAPHORIN SEMAPHORIN-3B binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon guidance#GO:0007411;axon development#GO:0061564;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;chemotaxis#GO:0006935 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000028412.2|UniProtKB=A0A2I2YQT0 A0A2I2YQT0 LOC101137281 PTHR26450:SF156 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52R1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027908.2|UniProtKB=G3SBD9 G3SBD9 PTHR20515:SF2 BETA-DEFENSIN DEFENSIN BETA 4A receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677 locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;cell motility#GO:0048870;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cell chemotaxis#GO:0060326;chemotaxis#GO:0006935;defense response to bacterium#GO:0042742;cellular response to chemical stimulus#GO:0070887;response to bacterium#GO:0009617;response to other organism#GO:0051707;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000883.3|UniProtKB=G3QF10 G3QF10 SYNE4 PTHR21640:SF1 FAMILY NOT NAMED NESPRIN-4 GORGO|Ensembl=ENSGGOG00000025246.2|UniProtKB=A0A2I2Y2G8 A0A2I2Y2G8 PTHR11363:SF4 60S RIBOSOMAL PROTEIN L3-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL3 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;structural molecule activity#GO:0005198 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014393.3|UniProtKB=G3REP5 G3REP5 NDUFS3 PTHR10884:SF16 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000009929.3|UniProtKB=G3R381 G3R381 ACOT11 PTHR11049:SF1 ACYL COENZYME A THIOESTER HYDROLASE ACYL-COENZYME A THIOESTERASE 11 hydrolase activity#GO:0016787;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790 metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000011396.3|UniProtKB=G3R6Z0 G3R6Z0 AP4B1 PTHR11134:SF4 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-4 COMPLEX SUBUNIT BETA-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;AP-type membrane coat adaptor complex#GO:0030119 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000014853.3|UniProtKB=G3RFW1 G3RFW1 GLT1D1 PTHR46660:SF2 FAMILY NOT NAMED GLYCOSYLTRANSFERASE 1 DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000014828.3|UniProtKB=G3RQC8 G3RQC8 CDK12 PTHR24056:SF126 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 12 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000010415.3|UniProtKB=G3R4F9 G3R4F9 PDLIM4 PTHR24214:SF6 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 4 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;circulatory system development#GO:0072359;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;heart development#GO:0007507;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;myofibril#GO:0030016;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;actomyosin#GO:0042641;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;I band#GO:0031674;actin filament#GO:0005884;stress fiber#GO:0001725;cytoskeleton#GO:0005856;adherens junction#GO:0005912;cell junction#GO:0030054;sarcomere#GO:0030017;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000023561.2|UniProtKB=A0A2I2YSZ1 A0A2I2YSZ1 PTHR10802:SF6 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 HOMOLOG transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000026944.2|UniProtKB=G3RUZ8 G3RUZ8 CRYGC PTHR11818:SF32 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN C structural molecule activity#GO:0005198 lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000025414.2|UniProtKB=G3SEF6 G3SEF6 KIAA1210 PTHR47743:SF2 KIAA1210 / KIAA1211 FAMILY MEMBER ACROSOMAL PROTEIN KIAA1210 GORGO|Ensembl=ENSGGOG00000015017.3|UniProtKB=G3RWT5 G3RWT5 GTF2B PTHR11618:SF77 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION INITIATION FACTOR IIB catalytic activity#GO:0003824;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;transferase activity#GO:0016740;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;acetyltransferase activity#GO:0016407;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367 nucleus#GO:0005634;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 General transcription regulation#P00023>TFIIB#P00668;Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397 GORGO|Ensembl=ENSGGOG00000002856.3|UniProtKB=G3RY38 G3RY38 MEF2C PTHR11945:SF25 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2C protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;histone deacetylase binding#GO:0042826 positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;heart development#GO:0007507;positive regulation of macromolecule metabolic process#GO:0010604;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MADS box transcription factor#PC00250 Oxidative stress response#P00046>MEF-2#P01128;p38 MAPK pathway#P05918>MEF#P06023;CCKR signaling map#P06959>MEF2C#P07222 GORGO|Ensembl=ENSGGOG00000015109.3|UniProtKB=G3RGK1 G3RGK1 SAFB PTHR15683:SF9 SCAFFOLD ATTACHMENT FACTOR B-RELATED SCAFFOLD ATTACHMENT FACTOR B1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565 cellular response to steroid hormone stimulus#GO:0071383;response to hormone#GO:0009725;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;nuclear receptor-mediated signaling pathway#GO:0141193;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;response to steroid hormone#GO:0048545;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;intracellular signal transduction#GO:0035556;response to endogenous stimulus#GO:0009719;estrogen receptor signaling pathway#GO:0030520;regulation of biological process#GO:0050789;steroid hormone receptor signaling pathway#GO:0043401;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;intracellular receptor signaling pathway#GO:0030522 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000005554.3|UniProtKB=G3S2X4 G3S2X4 PTHR11108:SF1 FERROCHELATASE FERROCHELATASE, MITOCHONDRIAL lyase activity#GO:0016829;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014;cellular process#GO:0009987;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;porphyrin-containing compound biosynthetic process#GO:0006779;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 lyase#PC00144 Heme biosynthesis#P02746>Ferrochelatase#P02972 GORGO|Ensembl=ENSGGOG00000026690.2|UniProtKB=G3RRW2 G3RRW2 ANGPTL1 PTHR19143:SF25 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000025975.2|UniProtKB=G3S9B2 G3S9B2 FAS PTHR46874:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;death receptor activity#GO:0005035 regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;lymphocyte homeostasis#GO:0002260;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;neuron apoptotic process#GO:0051402;regulation of cellular response to stress#GO:0080135;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;multicellular organismal-level homeostasis#GO:0048871;necroptotic process#GO:0070266;negative regulation of apoptotic process#GO:0043066;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;homeostasis of number of cells#GO:0048872;cell communication#GO:0007154;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;regulation of cell communication#GO:0010646 side of membrane#GO:0098552;membrane microdomain#GO:0098857;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane raft#GO:0045121;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 p53 pathway#P00059>FAS#G01571;FAS signaling pathway#P00020>Fas#P00612;Apoptosis signaling pathway#P00006>FAS#P00289 GORGO|Ensembl=ENSGGOG00000014560.3|UniProtKB=G3RF58 G3RF58 NAT10 PTHR10925:SF5 N-ACETYLTRANSFERASE 10 RNA CYTIDINE ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a tRNA#GO:0140101;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA modification#GO:0000154;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;tRNA modification#GO:0006400 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000007538.3|UniProtKB=G3QX49 G3QX49 GYG2 PTHR11183:SF167 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN-2 glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000043192.1|UniProtKB=A0A2I2YA11 A0A2I2YA11 LYSMD3 PTHR20932:SF5 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 3-RELATED cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000040812.1|UniProtKB=A0A2I2Y7V8 A0A2I2Y7V8 PTHR42152:SF1 PROTEIN GDF5OS, MITOCHONDRIAL PROTEIN GDF5-AS1, MITOCHONDRIAL GORGO|Ensembl=ENSGGOG00000004725.3|UniProtKB=G3QPX1 G3QPX1 PAOX PTHR10742:SF429 FLAVIN MONOAMINE OXIDASE PEROXISOMAL N(1)-ACETYL-SPERMINE_SPERMIDINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;polyamine catabolic process#GO:0006598;amine catabolic process#GO:0009310;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000007486.3|UniProtKB=G3QWZ9 G3QWZ9 UFC1 PTHR12921:SF0 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 response to stress#GO:0006950;reticulophagy#GO:0061709;autophagy#GO:0006914;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;catabolic process#GO:0009056;macroautophagy#GO:0016236;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;process utilizing autophagic mechanism#GO:0061919 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000036150.1|UniProtKB=A0A2I2Y5M3 A0A2I2Y5M3 PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;chromosome organization#GO:0051276;regulation of biosynthetic process#GO:0009889;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;negative regulation of DNA-templated transcription#GO:0045892 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 protein modifying enzyme#PC00260 GORGO|Gene=CSTB|UniProtKB=Q76LA0 Q76LA0 CSTB PTHR11414:SF22 CYSTATIN FAMILY MEMBER CYSTATIN-B endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000016013.3|UniProtKB=G3RIV8 G3RIV8 REPS2 PTHR11216:SF64 EH DOMAIN RALBP1-ASSOCIATED EPS DOMAIN-CONTAINING PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005353.3|UniProtKB=G3QRI7 G3QRI7 TMEM86B PTHR31885:SF7 GH04784P LYSOPLASMALOGENASE TMEM86B intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ether hydrolase activity#GO:0016803;isomerase activity#GO:0016853 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005557.3|UniProtKB=G3QS20 G3QS20 RAB7A PTHR47981:SF13 RAB FAMILY RAS-RELATED PROTEIN RAB-7A GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;endocytosis#GO:0006897;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular transport#GO:0046907;phagocytosis#GO:0006909;phagolysosome assembly#GO:0001845;transport#GO:0006810;lytic vacuole organization#GO:0080171;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;lysosome organization#GO:0007040;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;late endosome#GO:0005770;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000039973.1|UniProtKB=A0A2I2Z2W5 A0A2I2Z2W5 GJE1 PTHR11984:SF1 CONNEXIN GAP JUNCTION EPSILON-1 PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000008563.3|UniProtKB=G3QZR0 G3QZR0 ALDH1A1 PTHR11699:SF140 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE 1A1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 biological regulation#GO:0065007;biosynthetic process#GO:0009058;aldehyde catabolic process#GO:0046185;hormone metabolic process#GO:0042445;terpenoid biosynthetic process#GO:0016114;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;monocarboxylic acid biosynthetic process#GO:0072330;diterpenoid biosynthetic process#GO:0016102;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;regulation of hormone levels#GO:0010817;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;isoprenoid biosynthetic process#GO:0008299;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000038067.1|UniProtKB=A0A2I2YRW3 A0A2I2YRW3 PTHR10902:SF36 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;translation#GO:0006412;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011665.3|UniProtKB=A0A2I2ZX66 A0A2I2ZX66 FYTTD1 PTHR21038:SF2 40-2-3 PROTEIN-RELATED UAP56-INTERACTING FACTOR protein-RNA adaptor activity#GO:0140517;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear speck#GO:0016607;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000028409.2|UniProtKB=A0A2I2YRD9 A0A2I2YRD9 PRR29 PTHR28604:SF1 FAMILY NOT NAMED PROLINE-RICH PROTEIN 29 GORGO|Ensembl=ENSGGOG00000003722.3|UniProtKB=G3QMC1 G3QMC1 ETFBKMT PTHR43648:SF3 ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of lipid catabolic process#GO:0050994;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;negative regulation of catabolic process#GO:0009895;negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000011266.3|UniProtKB=G3R6M2 G3R6M2 LRRD1 PTHR47186:SF61 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57 PROTEIN LAP1 GORGO|Ensembl=ENSGGOG00000012139.4|UniProtKB=G3R8X1 G3R8X1 TOX PTHR45781:SF4 AGAP000281-PA THYMOCYTE SELECTION-ASSOCIATED HIGH MOBILITY GROUP BOX PROTEIN TOX binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;DNA binding#GO:0003677 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;hemopoiesis#GO:0030097;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;leukocyte differentiation#GO:0002521;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007684.4|UniProtKB=A0A2I2Y4S8 A0A2I2Y4S8 SH3GL2 PTHR14167:SF50 SH3 DOMAIN-CONTAINING ENDOPHILIN-A1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endocytosis#GO:0006897;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;cellular localization#GO:0051641;localization#GO:0051179;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;membrane organization#GO:0061024;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;synaptic vesicle cycle#GO:0099504 glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829;presynapse#GO:0098793;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016916.4|UniProtKB=A0A2I2Z4G4 A0A2I2Z4G4 AGAP3 PTHR45819:SF2 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;enzyme activator activity#GO:0008047;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function activator activity#GO:0140677;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000036917.1|UniProtKB=A0A2I2YFF2 A0A2I2YFF2 LOC101137310 PTHR13068:SF203 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 4, MITOCHONDRIAL negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;mitochondrial ribosome assembly#GO:0061668;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;organelle assembly#GO:0070925;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular component assembly#GO:0022607;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of biological process#GO:0048519;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000011299.3|UniProtKB=G3R6Q1 G3R6Q1 EPC2 PTHR14898:SF4 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB HOMOLOG 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000002408.3|UniProtKB=G3QIZ6 G3QIZ6 CPA2 PTHR11705:SF71 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A2 exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000012777.3|UniProtKB=G3RAI9 G3RAI9 ETNK2 PTHR22603:SF94 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000026526.2|UniProtKB=G3SJW4 G3SJW4 PTHR23267:SF472 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-20-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000009726.4|UniProtKB=G3R2P1 G3R2P1 GUCY1A2 PTHR45655:SF7 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT ALPHA-2 catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;lyase activity#GO:0016829;guanylate cyclase activity#GO:0004383 response to stimulus#GO:0050896;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;catalytic complex#GO:1902494 guanylate cyclase#PC00114;cyclase#PC00079 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 GORGO|Ensembl=ENSGGOG00000010271.3|UniProtKB=G3R437 G3R437 RELT PTHR47397:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19L TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19L animal organ morphogenesis#GO:0009887;odontogenesis of dentin-containing tooth#GO:0042475;odontogenesis#GO:0042476;programmed cell death#GO:0012501;amelogenesis#GO:0097186;cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915;anatomical structure morphogenesis#GO:0009653;animal organ development#GO:0048513;anatomical structure development#GO:0048856;anatomical structure formation involved in morphogenesis#GO:0048646;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009329.3|UniProtKB=G3R1N6 G3R1N6 TC2N PTHR46887:SF1 TANDEM C2 DOMAINS NUCLEAR PROTEIN TANDEM C2 DOMAINS NUCLEAR PROTEIN GORGO|Ensembl=ENSGGOG00000014914.3|UniProtKB=A0A2I2Z3F7 A0A2I2Z3F7 PTHR23317:SF77 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 9 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000011221.3|UniProtKB=G3R6I6 G3R6I6 ACP7 PTHR45867:SF3 PURPLE ACID PHOSPHATASE ACID PHOSPHATASE TYPE 7 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000009456.3|UniProtKB=G3R1Z8 G3R1Z8 MAGEF1 PTHR11736:SF61 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN F1 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008511.3|UniProtKB=G3QZK6 G3QZK6 SLC7A13 PTHR11785:SF238 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 7 MEMBER 13 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007671.3|UniProtKB=G3QXG9 G3QXG9 GRAMD1B PTHR23319:SF3 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-B sterol transfer activity#GO:0120015;transporter activity#GO:0005215;alcohol binding#GO:0043178;cholesterol transfer activity#GO:0120020;steroid binding#GO:0005496;binding#GO:0005488;small molecule binding#GO:0036094;lipid carrier activity#GO:0005319;sterol binding#GO:0032934;molecular carrier activity#GO:0140104;cholesterol binding#GO:0015485;lipid transfer activity#GO:0120013;lipid binding#GO:0008289 lipid localization#GO:0010876;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;sterol transport#GO:0015918;cellular localization#GO:0051641;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lipid transport#GO:0006869;intracellular sterol transport#GO:0032366 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane contact site#GO:0044232;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 GORGO|Ensembl=ENSGGOG00000011450.3|UniProtKB=A0A2I2ZSL8 A0A2I2ZSL8 SLC22A11 PTHR24064:SF241 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 11 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000000407.3|UniProtKB=G3SHG4 G3SHG4 PROZ PTHR24278:SF20 COAGULATION FACTOR VITAMIN K-DEPENDENT PROTEIN Z hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 hemostasis#GO:0007599;response to stress#GO:0006950;response to wounding#GO:0009611;coagulation#GO:0050817;multicellular organismal process#GO:0032501;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;biological regulation#GO:0065007;blood coagulation#GO:0007596;regulation of biological quality#GO:0065008;wound healing#GO:0042060 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 Blood coagulation#P00011>PZ#P00407 GORGO|Ensembl=ENSGGOG00000004538.3|UniProtKB=G3QPF4 G3QPF4 PCSK1N PTHR15531:SF0 PROSAAS PROSAAS enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;hormone metabolic process#GO:0042445;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000009367.3|UniProtKB=Q0MQF2 Q0MQF2 NDUFB10 PTHR13094:SF1 NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009560.3|UniProtKB=G3R295 G3R295 ANGEL2 PTHR12121:SF27 CARBON CATABOLITE REPRESSOR PROTEIN 4 RNA 2',3'-CYCLIC PHOSPHATASE ANGEL2 RNA binding#GO:0003723;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;RNA nuclease activity#GO:0004540;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;mRNA binding#GO:0003729;exonuclease activity#GO:0004527;binding#GO:0005488;3'-5'-RNA exonuclease activity#GO:0000175;phosphoric ester hydrolase activity#GO:0042578;mRNA 3'-UTR binding#GO:0003730;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098 regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;mRNA processing#GO:0006397;RNA destabilization#GO:0050779;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial RNA processing#GO:0000963;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of mRNA metabolic process#GO:1903313;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000015059.3|UniProtKB=G3RGF2 G3RGF2 CRIPT PTHR11805:SF2 CYSTEINE-RICH PDZ-BINDING PROTEIN CYSTEINE-RICH PDZ-BINDING PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;neuron projection#GO:0043005;dendritic tree#GO:0097447 GORGO|Ensembl=ENSGGOG00000014060.3|UniProtKB=G3RDV2 G3RDV2 NIF3L1 PTHR13799:SF13 NGG1 INTERACTING FACTOR 3 NIF3-LIKE PROTEIN 1 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000006691.3|UniProtKB=G3QUY5 G3QUY5 PLVAP PTHR21687:SF5 PLASMALEMMA VESICLE-ASSOCIATED PROTEIN PLASMALEMMA VESICLE-ASSOCIATED PROTEIN positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;regulation of cell migration#GO:0030334;system process#GO:0003008;positive regulation of locomotion#GO:0040017;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte migration#GO:0002685;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;regulation of cell motility#GO:2000145 GORGO|Gene=CYP2F5|UniProtKB=Q8WNE1 Q8WNE1 CYP2F5 PTHR24300:SF275 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2F1 heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;binding#GO:0005488;tetrapyrrole binding#GO:0046906 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000038896.1|UniProtKB=A0A2I2Y8U4 A0A2I2Y8U4 PERP PTHR14399:SF4 P53-INDUCED PROTEIN RELATED P53 APOPTOSIS EFFECTOR RELATED TO PMP-22 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 p53 pathway#P00059>PERP#G01565 GORGO|Ensembl=ENSGGOG00000040873.1|UniProtKB=G3RX63 G3RX63 ACAD11 PTHR48083:SF42 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE FAMILY MEMBER 11 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000014671.3|UniProtKB=G3RFE5 G3RFE5 RERGL PTHR45704:SF9 RAS-LIKE FAMILY MEMBER 11 RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR-LIKE PROTEIN GORGO|Ensembl=ENSGGOG00000008271.3|UniProtKB=G3QYY6 G3QYY6 PTHR11783:SF77 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1C3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002304.3|UniProtKB=A0A2I2YSX7 A0A2I2YSX7 PHF21A PTHR24102:SF6 PHD FINGER PROTEIN PHD FINGER PROTEIN 21A chromatin binding#GO:0003682;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000024510.2|UniProtKB=G3RX48 G3RX48 LOC101151121 PTHR13718:SF127 RIBOSOMAL S SUBUNIT 40S RIBOSOMAL PROTEIN S2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007607.3|UniProtKB=G3QXA5 G3QXA5 PTHR11839:SF15 UDP/ADP-SUGAR PYROPHOSPHATASE URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT14 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135 metabolite interconversion enzyme#PC00262;pyrophosphatase#PC00196 GORGO|Ensembl=ENSGGOG00000002177.3|UniProtKB=G3SBI9 G3SBI9 CHN1 PTHR46075:SF1 CHIMERIN FAMILY MEMBER N-CHIMAERIN signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 GORGO|Ensembl=ENSGGOG00000010912.3|UniProtKB=G3R5R1 G3R5R1 PMPCA PTHR11851:SF192 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;peptidase complex#GO:1905368;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;endopeptidase complex#GO:1905369 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000001196.4|UniProtKB=G3QFU9 G3QFU9 F13A1 PTHR11590:SF42 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE COAGULATION FACTOR XIII A CHAIN catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;hemostasis#GO:0007599;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;blood coagulation, fibrin clot formation#GO:0072378;wound healing#GO:0042060;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;protein activation cascade#GO:0072376;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;coagulation#GO:0050817;response to wounding#GO:0009611;response to stress#GO:0006950;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;metabolic process#GO:0008152;blood coagulation#GO:0007596;macromolecule metabolic process#GO:0043170 transferase#PC00220 Blood coagulation#P00011>FXIIIa#P00419;Blood coagulation#P00011>FXIII#P00453 GORGO|Ensembl=ENSGGOG00000007244.3|UniProtKB=G3QWE1 G3QWE1 PDGFRB PTHR24416:SF53 TYROSINE-PROTEIN KINASE RECEPTOR PLATELET-DERIVED GROWTH FACTOR RECEPTOR BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;blood vessel morphogenesis#GO:0048514;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;chemotaxis#GO:0006935;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell chemotaxis#GO:0060326;system development#GO:0048731;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;developmental process#GO:0032502;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;cell migration#GO:0016477 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor B#P01156;Angiogenesis#P00005>PDGFR#P00230 GORGO|Ensembl=ENSGGOG00000001547.4|UniProtKB=G3QGR6 G3QGR6 MAN2A1 PTHR11607:SF69 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 glycosidase#PC00110;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000012105.3|UniProtKB=G3R8T5 G3R8T5 PARK7 PTHR48094:SF16 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED PARKINSON DISEASE PROTEIN 7 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;hydro-lyase activity#GO:0016836 small molecule catabolic process#GO:0044282;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular response to stimulus#GO:0051716;carboxylic acid biosynthetic process#GO:0046394;ketone metabolic process#GO:0042180;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular detoxification of aldehyde#GO:0110095;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;aldehyde catabolic process#GO:0046185;cellular response to toxic substance#GO:0097237;biosynthetic process#GO:0009058;detoxification#GO:0098754;response to chemical#GO:0042221;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;monocarboxylic acid biosynthetic process#GO:0072330;response to oxidative stress#GO:0006979;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003466.3|UniProtKB=G3QLR1 G3QLR1 PTHR19325:SF545 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT RECEPTOR TYPE 1 regulation of immune response#GO:0050776;T cell mediated immunity#GO:0002456;negative regulation of immune response#GO:0050777;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;regulation of immune effector process#GO:0002697;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;immune response#GO:0006955;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;adaptive immune response#GO:0002250;negative regulation of response to stimulus#GO:0048585 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;complement component#PC00078 GORGO|Ensembl=ENSGGOG00000005032.3|UniProtKB=G3QQR9 G3QQR9 COL13A1 PTHR24023:SF871 COLLAGEN ALPHA COLLAGEN ALPHA-1(XIII) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Gene=APOE|UniProtKB=Q9GLM8 Q9GLM8 APOE PTHR18976:SF2 APOLIPOPROTEIN APOLIPOPROTEIN E binding#GO:0005488;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;sterol transfer activity#GO:0120015;transporter activity#GO:0005215;cholesterol transfer activity#GO:0120020;molecular function regulator activity#GO:0098772 lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;secondary alcohol metabolic process#GO:1902652;organophosphate ester transport#GO:0015748;small molecule metabolic process#GO:0044281;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;cholesterol efflux#GO:0033344;cellular process#GO:0009987;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;steroid metabolic process#GO:0008202;phospholipid transport#GO:0015914;lipid transport#GO:0006869;cholesterol metabolic process#GO:0008203;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;transport#GO:0006810;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;sterol transport#GO:0015918;establishment of localization#GO:0051234;sterol metabolic process#GO:0016125 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;very-low-density lipoprotein particle#GO:0034361;high-density lipoprotein particle#GO:0034364;membrane-bounded organelle#GO:0043227;plasma lipoprotein particle#GO:0034358;lipoprotein particle#GO:1990777;protein-lipid complex#GO:0032994;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000016734.3|UniProtKB=G3RKP7 G3RKP7 TAB2 PTHR46253:SF2 TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 2 K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;protein binding#GO:0005515 regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;system development#GO:0048731;positive regulation of signaling#GO:0023056;anatomical structure development#GO:0048856;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;heart development#GO:0007507;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;multicellular organism development#GO:0007275;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502 p38 MAPK pathway#P05918>TAB2#P06033 GORGO|Ensembl=ENSGGOG00000028251.2|UniProtKB=G3S6K3 G3S6K3 IRF8 PTHR11949:SF7 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000015380.3|UniProtKB=G3RH86 G3RH86 TSPAN10 PTHR19282:SF550 TETRASPANIN TETRASPANIN-10 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003117.3|UniProtKB=G3QKT1 G3QKT1 GARIN2 PTHR22574:SF6 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 2 GORGO|Ensembl=ENSGGOG00000005360.3|UniProtKB=A0A2I2Y8F3 A0A2I2Y8F3 SNRNP27 PTHR31077:SF2 U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000015221.3|UniProtKB=G3RGU3 G3RGU3 RLF PTHR15507:SF18 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN RLF transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000004185.3|UniProtKB=A0A2I2ZI34 A0A2I2ZI34 POLR3E PTHR12069:SF0 DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000001227.3|UniProtKB=G3QFX5 G3QFX5 RTP4 PTHR14402:SF23 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 4 signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;intracellular protein localization#GO:0008104;protein targeting to membrane#GO:0006612;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;protein insertion into membrane#GO:0051205;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;membrane organization#GO:0061024;detection of stimulus involved in sensory perception#GO:0050906;macromolecule localization#GO:0033036;detection of stimulus#GO:0051606;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;detection of chemical stimulus involved in sensory perception#GO:0050907;localization within membrane#GO:0051668;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;response to stimulus#GO:0050896;protein targeting#GO:0006605;cellular component organization#GO:0016043;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011739.3|UniProtKB=G3R7V2 G3R7V2 POLR2G PTHR12709:SF4 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000003950.3|UniProtKB=A0A2I2Y5B1 A0A2I2Y5B1 RBM39 PTHR48036:SF10 SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED RNA-BINDING PROTEIN 39 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000039890.1|UniProtKB=A0A2I2YXB2 A0A2I2YXB2 PTHR26452:SF775 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H8 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027790.2|UniProtKB=G3S521 G3S521 ARL8A PTHR45732:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8A microtubule-based transport#GO:0099111;axonal transport#GO:0098930;lysosomal transport#GO:0007041;anterograde axonal transport#GO:0008089;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based movement#GO:0007018;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;endosomal transport#GO:0016197;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;vesicle-mediated transport#GO:0016192;cytoskeleton-dependent intracellular transport#GO:0030705 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000036165.1|UniProtKB=G3SKQ6 G3SKQ6 PTHR11353:SF54 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ZETA macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein folding chaperone complex#GO:0101031;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000000108.3|UniProtKB=A0A2I2Y6I6 A0A2I2Y6I6 CAMK2A PTHR24347:SF384 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;calcium/calmodulin-dependent protein kinase activity#GO:0004683;catalytic activity, acting on a protein#GO:0140096;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007 postsynaptic density#GO:0014069;axon#GO:0030424;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995 non-receptor serine/threonine protein kinase#PC00167 Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847 GORGO|Ensembl=ENSGGOG00000037776.1|UniProtKB=A0A2I2ZLZ9 A0A2I2ZLZ9 PTHR10064:SF2 60S RIBOSOMAL PROTEIN L22 LARGE RIBOSOMAL SUBUNIT PROTEIN EL22 nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008167.3|UniProtKB=G3QYP3 G3QYP3 RBP4 PTHR11873:SF2 RETINOL-BINDING PROTEIN 4 RETINOL-BINDING PROTEIN 4 binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;alcohol binding#GO:0043178 transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000006601.3|UniProtKB=G3SCB0 G3SCB0 DAXX PTHR12766:SF13 DEATH DOMAIN-ASSOCIATED PROTEIN 6 DAXX DEATH DOMAIN-ASSOCIATED PROTEIN 6 DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cell death#GO:0008219;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 Apoptosis signaling pathway#P00006>DAXX#P00296;FAS signaling pathway#P00020>DAXX#P00602 GORGO|Ensembl=ENSGGOG00000042271.1|UniProtKB=A0A2I2Z8B4 A0A2I2Z8B4 LOC101152662 PTHR11831:SF48 30S 40S RIBOSOMAL PROTEIN SMALL RIBOSOMAL SUBUNIT PROTEIN US4 RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;rRNA binding#GO:0019843 cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005591.3|UniProtKB=G3QS51 G3QS51 SLU7 PTHR12942:SF2 STEP II SPLICING FACTOR SLU7 PRE-MRNA-SPLICING FACTOR SLU7 RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000005886.3|UniProtKB=G3QSW2 G3QSW2 URI1 PTHR15111:SF2 RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3 UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;phosphatase regulator activity#GO:0019208;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;enzyme inhibitor activity#GO:0004857 regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of apoptotic process#GO:0043066;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of apoptotic process#GO:0042981;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;negative regulation of signal transduction#GO:0009968;negative regulation of programmed cell death#GO:0043069;negative regulation of macromolecule biosynthetic process#GO:0010558 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000013476.3|UniProtKB=G3RCB8 G3RCB8 PTHR31965:SF1 TRANSMEMBRANE PROTEIN 42 TRANSMEMBRANE PROTEIN 42 GORGO|Ensembl=ENSGGOG00000005822.3|UniProtKB=G3QSQ7 G3QSQ7 OPN1SW PTHR24240:SF16 OPSIN SHORT-WAVE-SENSITIVE OPSIN 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 detection of stimulus#GO:0051606;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to radiation#GO:0071478;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000004585.3|UniProtKB=G3QPJ7 G3QPJ7 TMEM199 PTHR31394:SF1 TRANSMEMBRANE PROTEIN 199 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA12 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008675.3|UniProtKB=G3R014 G3R014 TTK PTHR22974:SF21 MIXED LINEAGE PROTEIN KINASE DUAL SPECIFICITY PROTEIN KINASE TTK protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;meiotic cell cycle process#GO:1903046;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of meiotic cell cycle#GO:0051445;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell cycle#GO:0045786;negative regulation of chromosome segregation#GO:0051985;meiotic cell cycle#GO:0051321;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;chromosome segregation#GO:0007059;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cell communication#GO:0007154;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of chromosome organization#GO:2001251;sexual reproduction#GO:0019953;regulation of reproductive process#GO:2000241;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000024157.2|UniProtKB=G3S4Q5 G3S4Q5 TNP2 PTHR17488:SF0 NUCLEAR TRANSITION PROTEIN 2 NUCLEAR TRANSITION PROTEIN 2 multi-multicellular organism process#GO:0044706;acrosome reaction#GO:0007340;developmental process involved in reproduction#GO:0003006;single fertilization#GO:0007338;reproductive process#GO:0022414;fertilization#GO:0009566;multicellular organismal process#GO:0032501;gamete generation#GO:0007276;male gamete generation#GO:0048232;developmental process#GO:0032502;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;multicellular organismal reproductive process#GO:0048609 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000002283.3|UniProtKB=G3QIN3 G3QIN3 ACSM6 PTHR43605:SF1 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM6, MITOCHONDRIAL acyltransferase activity#GO:0016746;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000013451.3|UniProtKB=A0A2I2YUF9 A0A2I2YUF9 PTHR12247:SF64 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 2 binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000092.3|UniProtKB=G3QCY8 G3QCY8 ESPNL PTHR24153:SF0 ESPIN ESPIN-LIKE PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;system process#GO:0003008;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;sensory perception of sound#GO:0007605;actin cytoskeleton organization#GO:0030036;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;actin filament-based process#GO:0030029 plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin-based cell projection#GO:0098858;neuron projection#GO:0043005;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stereocilium#GO:0032420 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000041128.1|UniProtKB=A0A2I2Y3G1 A0A2I2Y3G1 SMIM3 PTHR37859:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 3 SMALL INTEGRAL MEMBRANE PROTEIN 3 GORGO|Ensembl=ENSGGOG00000014554.3|UniProtKB=G3RF39 G3RF39 PTHR47745:SF1 IZUMO SPERM-EGG FUSION PROTEIN 2 IZUMO SPERM-EGG FUSION PROTEIN 2 GORGO|Ensembl=ENSGGOG00000023216.2|UniProtKB=G3SFF5 G3SFF5 TTC21B PTHR14699:SF1 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21B intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;cellular component organization#GO:0016043;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;protein localization to cilium#GO:0061512 intraciliary transport particle#GO:0030990;protein-containing complex#GO:0032991;intraciliary transport particle A#GO:0030991 GORGO|Ensembl=ENSGGOG00000023415.2|UniProtKB=G3RSF8 G3RSF8 LOC101126019 PTHR26453:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027432.2|UniProtKB=A0A2I2YP36 A0A2I2YP36 PTHR10418:SF3 SECURIN-3 PITUITARY TUMOR-TRANSFORMING GENE 3 PROTEIN-RELATED endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 cellular process#GO:0009987;organelle organization#GO:0006996;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cell cycle#GO:0007049;reproductive process#GO:0022414;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000012971.3|UniProtKB=G3RB20 G3RB20 TDRD6 PTHR22948:SF15 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 6 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002776.3|UniProtKB=G3QJY0 G3QJY0 CCAR1 PTHR14304:SF14 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000026106.2|UniProtKB=G3SA52 G3SA52 PTHR45880:SF4 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000009190.3|UniProtKB=G3R1C7 G3R1C7 CORO2A PTHR10856:SF2 CORONIN CORONIN-2A protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000006056.3|UniProtKB=G3QTB8 G3QTB8 ADAM9 PTHR11905:SF136 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 9 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 animal organ development#GO:0048513;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;male sex differentiation#GO:0046661;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;gonad development#GO:0008406;multicellular organismal process#GO:0032501;cellular process#GO:0009987;sex differentiation#GO:0007548;male gonad development#GO:0008584;reproductive system development#GO:0061458;system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;reproductive process#GO:0022414;reproductive structure development#GO:0048608;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 metalloprotease#PC00153;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>MDC9#P00090 GORGO|Ensembl=ENSGGOG00000001710.3|UniProtKB=G3QH63 G3QH63 FAM118A PTHR28623:SF2 PROTEIN FAM118B PROTEIN FAM118A hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 GORGO|Ensembl=ENSGGOG00000025582.2|UniProtKB=G3RTN1 G3RTN1 RPL26L1 PTHR11143:SF10 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER RIBOSOMAL PROTEIN UL24-LIKE structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000000685.3|UniProtKB=G3QEI0 G3QEI0 SERGEF PTHR45622:SF78 UBIQUITIN-PROTEIN LIGASE E3A-RELATED SECRETION-REGULATING GUANINE NUCLEOTIDE EXCHANGE FACTOR transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of secretion#GO:0051046;regulation of establishment of protein localization#GO:0070201;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;negative regulation of transport#GO:0051051;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of protein secretion#GO:0050708;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;post-translational protein modification#GO:0043687;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;regulation of secretion by cell#GO:1903530;regulation of protein localization#GO:0032880;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of protein transport#GO:0051223;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of localization#GO:0032879;regulation of transport#GO:0051049;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012378.3|UniProtKB=G3RW57 G3RW57 ZNF599 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000026678.2|UniProtKB=G3RB75 G3RB75 FRG2C PTHR31883:SF1 PROTEIN FRG2-RELATED PROTEIN FRG2-LIKE-2 GORGO|Ensembl=ENSGGOG00000008308.3|UniProtKB=G3QZ19 G3QZ19 PTHR24028:SF97 CADHERIN-87A PROTOCADHERIN BETA-15 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000003542.3|UniProtKB=G3QLW1 G3QLW1 ZFAND4 PTHR46728:SF1 AN1-TYPE ZINC FINGER PROTEIN 4 AN1-TYPE ZINC FINGER PROTEIN 4 GORGO|Ensembl=ENSGGOG00000000429.3|UniProtKB=A0A2I2ZL53 A0A2I2ZL53 MKRN2 PTHR11224:SF17 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-2 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008819.3|UniProtKB=G3R0D4 G3R0D4 LOC101153318 PTHR48002:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015009.3|UniProtKB=G3RGA3 G3RGA3 UBE2A PTHR24067:SF243 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 A transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000001402.3|UniProtKB=G3QGC9 G3QGC9 ZFP36L2 PTHR12547:SF174 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36L2 molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182;protein-macromolecule adaptor activity#GO:0030674;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000002854.3|UniProtKB=G3QK37 G3QK37 SYCE3 PTHR36686:SF1 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 3 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 3 meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;synaptonemal complex assembly#GO:0007130;cellular component assembly#GO:0022607;homologous chromosome pairing at meiosis#GO:0007129;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;homologous recombination#GO:0035825;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;central element#GO:0000801;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;condensed chromosome#GO:0000793;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000022580.2|UniProtKB=G3SF88 G3SF88 PURB PTHR12611:SF4 PUR-TRANSCRIPTIONAL ACTIVATOR TRANSCRIPTIONAL REGULATOR PROTEIN PUR-BETA transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000009145.3|UniProtKB=G3R178 G3R178 LOC101124039 PTHR26450:SF44 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51M1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006194.3|UniProtKB=G3QTN1 G3QTN1 NONO PTHR23189:SF15 RNA RECOGNITION MOTIF-CONTAINING NON-POU DOMAIN-CONTAINING OCTAMER-BINDING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000022101.2|UniProtKB=G3S0S8 G3S0S8 SPRY3 PTHR12365:SF9 SPROUTY PROTEIN SPROUTY HOMOLOG 3 molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;protein kinase regulator activity#GO:0019887;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857 negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of signal transduction#GO:0009968;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of Ras protein signal transduction#GO:0046578;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>Spry#P00626;EGF receptor signaling pathway#P00018>Spry#P00541;EGF receptor signaling pathway#P00018>SPRY#G01511 GORGO|Ensembl=ENSGGOG00000003225.3|UniProtKB=G3QL29 G3QL29 LAG3 PTHR11890:SF18 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER LYMPHOCYTE ACTIVATION GENE 3 PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037488.1|UniProtKB=A0A2I2ZD57 A0A2I2ZD57 PTHR24031:SF620 RNA HELICASE RNA HELICASE macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytoplasmic stress granule#GO:0010494;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000042395.1|UniProtKB=A0A2I2YNT7 A0A2I2YNT7 INIP PTHR31526:SF3 SOSS COMPLEX SUBUNIT C SOSS COMPLEX SUBUNIT C DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007272.3|UniProtKB=G3QWF7 G3QWF7 XAGE5 PTHR14047:SF38 P ANTIGEN FAMILY MEMBER 5-RELATED X ANTIGEN FAMILY MEMBER 5 GORGO|Ensembl=ENSGGOG00000001708.3|UniProtKB=G3QH60 G3QH60 CHMP6 PTHR22761:SF5 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 6 vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;multivesicular body sorting pathway#GO:0071985;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular localization#GO:0051641;membrane assembly#GO:0071709;cellular component organization#GO:0016043;late endosome to vacuole transport#GO:0045324 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000027833.2|UniProtKB=A0A2K5TIY7 A0A2K5TIY7 MSTN PTHR11848:SF278 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 8 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 animal organ development#GO:0048513;muscle organ development#GO:0007517;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;tissue development#GO:0009888;biological regulation#GO:0065007;transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;skeletal muscle tissue development#GO:0007519;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to growth factor stimulus#GO:0071363;muscle tissue development#GO:0060537;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;response to transforming growth factor beta#GO:0071559;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000002214.3|UniProtKB=G3QIH0 G3QIH0 HTR1D PTHR24247:SF17 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1D neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193 dendrite#GO:0030425;dendritic tree#GO:0097447;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 GORGO|Ensembl=ENSGGOG00000011441.3|UniProtKB=G3R732 G3R732 STAM2 PTHR45929:SF1 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE SIGNAL TRANSDUCING ADAPTER MOLECULE 2 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;cellular localization#GO:0051641;protein transport#GO:0015031;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of protein localization to vacuole#GO:0072666;late endosome to vacuole transport#GO:0045324;signaling#GO:0023052;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to vacuole#GO:0072665;localization#GO:0051179;cell communication#GO:0007154;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;biological regulation#GO:0065007 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014027.3|UniProtKB=G3RDR7 G3RDR7 SPATA3 PTHR22234:SF0 TESTIS SPERMATOCYTE APOPTOSIS-RELATED GENE 1 PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 3 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;motile cilium#GO:0031514;organelle#GO:0043226;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729 GORGO|Ensembl=ENSGGOG00000027528.2|UniProtKB=G3RQ70 G3RQ70 C18H16orf89 PTHR33539:SF1 UPF0764 PROTEIN C16ORF89 UPF0764 PROTEIN C16ORF89 membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011632.3|UniProtKB=G3R7K7 G3R7K7 C9H11orf52 PTHR37342:SF1 HYPOTHETICAL PROTEIN LOC689959 CHROMOSOME 11 OPEN READING FRAME 52 GORGO|Ensembl=ENSGGOG00000034868.2|UniProtKB=A0A2I2YQG2 A0A2I2YQG2 INPP5A PTHR12997:SF2 TYPE I INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE INOSITOL POLYPHOSPHATE-5-PHOSPHATASE A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphatase#PC00181;hydrolase#PC00121 PI3 kinase pathway#P00048>SHIP#P01200 GORGO|Ensembl=ENSGGOG00000042372.1|UniProtKB=A0A2I2YEY0 A0A2I2YEY0 PTHR17068:SF17 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of cell adhesion#GO:0007162;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000014709.3|UniProtKB=G3RFI3 G3RFI3 HTR3A PTHR18945:SF52 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Gonadotropin-releasing hormone receptor pathway#P06664>5-HT3AR#P06833;5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422 GORGO|Ensembl=ENSGGOG00000023247.2|UniProtKB=A0A2I2Z014 A0A2I2Z014 FAM136A PTHR21096:SF0 PROTEIN FAM136A TIM DOUBLE TWIN CX3C MOTIF PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000027.3|UniProtKB=G3QCT0 G3QCT0 MTCL3 PTHR15742:SF2 GIRDIN MICROTUBULE CROSS-LINKING FACTOR 3 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002299.3|UniProtKB=G3S2X9 G3S2X9 NRAP PTHR11039:SF39 NEBULIN NEBULIN-RELATED-ANCHORING PROTEIN binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;cardiac muscle cell differentiation#GO:0055007;cytoskeleton organization#GO:0007010;heart development#GO:0007507;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;actin filament organization#GO:0007015;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tissue development#GO:0009888 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;I band#GO:0031674 GORGO|Ensembl=ENSGGOG00000013339.3|UniProtKB=G3RBZ7 G3RBZ7 STK26 PTHR48012:SF7 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 26 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;signal transduction#GO:0007165;cellular process#GO:0009987 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000037676.1|UniProtKB=A0A2I2ZQD3 A0A2I2ZQD3 PLN PTHR21194:SF1 CARDIAC PHOSPHOLAMBAN PHOSPHOLAMBAN molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 regulation of biological quality#GO:0065008;regulation of heart contraction#GO:0008016;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;negative regulation of transport#GO:0051051;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;regulation of system process#GO:0044057;regulation of multicellular organismal process#GO:0051239;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269 membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007089.3|UniProtKB=G3QVZ0 G3QVZ0 NME5 PTHR46161:SF1 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE 5 transferase#PC00220;kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 GORGO|Ensembl=ENSGGOG00000039427.1|UniProtKB=A0A2I2ZCF0 A0A2I2ZCF0 CTNNA3 PTHR18914:SF21 ALPHA CATENIN CATENIN ALPHA-3 beta-catenin binding#GO:0008013;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;cell migration#GO:0016477;cell motility#GO:0048870 cell-cell contact zone#GO:0044291;anchoring junction#GO:0070161;intercalated disc#GO:0014704;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 non-motor actin binding protein#PC00165 Cadherin signaling pathway#P00012>alpha-catenin#P00467;Wnt signaling pathway#P00057>alpha-catenin#P01471 GORGO|Ensembl=ENSGGOG00000017137.3|UniProtKB=G3RLR4 G3RLR4 P4HTM PTHR10869:SF249 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT TRANSMEMBRANE PROLYL 4-HYDROXYLASE regulation of hemopoiesis#GO:1903706;regulation of cell differentiation#GO:0045595;regulation of myeloid cell differentiation#GO:0045637;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of cell development#GO:0060284 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012460.3|UniProtKB=G3R9Q9 G3R9Q9 C1QL2 PTHR22923:SF69 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 2 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037263.1|UniProtKB=A0A2I2YDF4 A0A2I2YDF4 BIRC5 PTHR46771:SF3 DETERIN BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5 cytoskeleton-dependent cytokinesis#GO:0061640;microtubule cytoskeleton organization#GO:0000226;cytokinesis#GO:0000910;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;mitotic cytokinesis#GO:0000281;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell division#GO:0051301;regulation of programmed cell death#GO:0043067;cell cycle#GO:0007049;negative regulation of biological process#GO:0048519;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;organelle organization#GO:0006996 membraneless organelle#GO:0043228;spindle#GO:0005819;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;kinetochore#GO:0000776 Angiogenesis#P00005>Survivin#P00198 GORGO|Ensembl=ENSGGOG00000009181.3|UniProtKB=G3R1B5 G3R1B5 PTHR11267:SF104 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 GORGO|Ensembl=ENSGGOG00000012774.3|UniProtKB=G3RAI8 G3RAI8 FNDC4 PTHR14470:SF2 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 4 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of response to external stimulus#GO:0032101;negative regulation of inflammatory response#GO:0050728;negative regulation of response to stimulus#GO:0048585;negative regulation of defense response#GO:0031348;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000034902.2|UniProtKB=G3SKL6 G3SKL6 LUZP2 PTHR22414:SF0 LEUCINE ZIPPER PROTEIN 2 LEUCINE ZIPPER PROTEIN 2 GORGO|Ensembl=ENSGGOG00000010275.3|UniProtKB=G3R440 G3R440 PIGP PTHR46346:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000011432.3|UniProtKB=G3R719 G3R719 LOC101148112 PTHR26453:SF154 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000038113.1|UniProtKB=A0A2I2Z787 A0A2I2Z787 PTHR14949:SF26 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 PROTEIN CRIPTO receptor serine/threonine kinase binding#GO:0033612;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of cellular process#GO:0050794;determination of left/right symmetry#GO:0007368;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;pattern specification process#GO:0007389;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;tube development#GO:0035295;cellular developmental process#GO:0048869;specification of symmetry#GO:0009799;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;response to stimulus#GO:0050896;cell differentiation#GO:0030154;circulatory system development#GO:0072359;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;animal gross anatomical part developmental process#GO:0160108;activin receptor signaling pathway#GO:0032924;heart development#GO:0007507;vasculogenesis#GO:0001570;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;determination of bilateral symmetry#GO:0009855;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;vasculature development#GO:0001944;left/right pattern formation#GO:0060972;cell surface receptor signaling pathway#GO:0007166 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000008425.3|UniProtKB=G3QZC7 G3QZC7 ARPC2 PTHR12058:SF0 ARP2/3 COMPLEX 34 KDA SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cortical actin cytoskeleton organization#GO:0030866;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin polymerization or depolymerization#GO:0008154;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;nucleus#GO:0005634 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 GORGO|Ensembl=ENSGGOG00000015271.3|UniProtKB=G3RGZ5 G3RGZ5 MIA3 PTHR23158:SF54 MELANOMA INHIBITORY ACTIVITY-RELATED TRANSPORT AND GOLGI ORGANIZATION PROTEIN 1 HOMOLOG localization#GO:0051179;protein secretion#GO:0009306;secretion#GO:0046903;cellular localization#GO:0051641;secretion by cell#GO:0032940;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;export from cell#GO:0140352;protein localization to extracellular region#GO:0071692;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000001583.3|UniProtKB=G3S931 G3S931 HEXD PTHR21040:SF6 BCDNA.GH04120 HEXOSAMINIDASE D hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 GORGO|Ensembl=ENSGGOG00000023617.2|UniProtKB=G3S9V6 G3S9V6 FASLG PTHR11471:SF33 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 6 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of apoptotic process#GO:0043065;regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;apoptotic signaling pathway#GO:0097190;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;programmed cell death#GO:0012501;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;cell death#GO:0008219;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Apoptosis signaling pathway#P00006>FAS ligand#P00326;FAS signaling pathway#P00020>FasL#P00617 GORGO|Ensembl=ENSGGOG00000005323.3|UniProtKB=G3QRG3 G3QRG3 RCOR1 PTHR16089:SF11 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000027852.2|UniProtKB=G3S402 G3S402 LOC101133585 PTHR26450:SF136 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52M1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037765.1|UniProtKB=A0A2I2Z287 A0A2I2Z287 PTHR12146:SF10 40S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN ES10 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009995.3|UniProtKB=A0A2I2ZFY5 A0A2I2ZFY5 CARNS1 PTHR48066:SF1 CARNOSINE SYNTHASE 1 CARNOSINE SYNTHASE 1 ligase activity, forming carbon-nitrogen bonds#GO:0016879;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;ligase activity#GO:0016874;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 GORGO|Ensembl=ENSGGOG00000023374.2|UniProtKB=G3SAQ4 G3SAQ4 PTHR47900:SF1 BETA-DEFENSIN 131A BETA-DEFENSIN 131A extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000000381.3|UniProtKB=G3SAI9 G3SAI9 NID1 PTHR46513:SF6 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED NIDOGEN-1 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008767.3|UniProtKB=G3R096 G3R096 TNK2 PTHR14254:SF6 GENE 33 POLYPEPTIDE ACTIVATED CDC42 KINASE 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000012093.4|UniProtKB=G3R8S9 G3R8S9 BMPR1B PTHR23255:SF62 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672 cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;regionalization#GO:0003002;multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;dorsal/ventral pattern formation#GO:0009953;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442 GORGO|Ensembl=ENSGGOG00000014903.3|UniProtKB=G3RG12 G3RG12 SLC15A1 PTHR11654:SF89 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 1 oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 import across plasma membrane#GO:0098739;cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;oligopeptide transport#GO:0006857;import into cell#GO:0098657;dipeptide transport#GO:0042938;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000026099.2|UniProtKB=G3RXU3 G3RXU3 RSPO3 PTHR46987:SF1 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004566.3|UniProtKB=G3RQC7 G3RQC7 SSR1 PTHR12924:SF0 TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000025163.2|UniProtKB=A0A2I2Z5R3 A0A2I2Z5R3 TMEM178B PTHR32005:SF1 TRANSMEMBRANE PROTEIN 178B-RELATED TRANSMEMBRANE PROTEIN 178B cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000015954.3|UniProtKB=G3RIP8 G3RIP8 PTHR12133:SF1 TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;methyltransferase complex#GO:0034708 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015041.3|UniProtKB=G3RGD4 G3RGD4 RCL1 PTHR11096:SF1 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;cyclase activity#GO:0009975;nuclease activity#GO:0004518 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015236.3|UniProtKB=G3RGV4 G3RGV4 RAB8A PTHR47980:SF33 LD44762P RAS-RELATED PROTEIN RAB-8A protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cilium assembly#GO:0060271;export from cell#GO:0140352;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;secretion by cell#GO:0032940;regulation of biological quality#GO:0065008;protein transport#GO:0015031;cilium organization#GO:0044782;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;protein localization to cell periphery#GO:1990778;exocytosis#GO:0006887;endosomal transport#GO:0016197;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;cellular component organization or biogenesis#GO:0071840;protein localization to synapse#GO:0035418;localization within membrane#GO:0051668;organelle assembly#GO:0070925;protein localization to cell junction#GO:1902414;localization#GO:0051179;secretion#GO:0046903;macromolecule localization#GO:0033036;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234 clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;endosome#GO:0005768;intracellular organelle#GO:0043229;trans-Golgi network transport vesicle#GO:0030140;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Huntington disease#P00029>Rab8#P00783 GORGO|Ensembl=ENSGGOG00000001262.3|UniProtKB=G3QG01 G3QG01 EXPH5 PTHR21469:SF4 EXOPHILIN-5 EXOPHILIN-5 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;transport#GO:0006810;vesicle-mediated transport#GO:0016192;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;intracellular signal transduction#GO:0035556;positive regulation of secretion#GO:0051047;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 GORGO|Ensembl=ENSGGOG00000013383.3|UniProtKB=G3RC36 G3RC36 WDR83 PTHR22842:SF3 WD40 REPEAT PROTEIN WD REPEAT DOMAIN-CONTAINING PROTEIN 83 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000006273.3|UniProtKB=G3QTV2 G3QTV2 RUNDC1 PTHR47194:SF5 SORTING NEXIN-29-RELATED RUN DOMAIN-CONTAINING PROTEIN 1 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015605.3|UniProtKB=G3S588 G3S588 INPP1 PTHR43028:SF3 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 INOSITOL POLYPHOSPHATE 1-PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;anterograde trans-synaptic signaling#GO:0098916 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000001915.3|UniProtKB=G3QHQ2 G3QHQ2 AWAT1 PTHR12317:SF16 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYL-COA WAX ALCOHOL ACYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000012442.3|UniProtKB=G3RN01 G3RN01 HIPK1 PTHR24058:SF43 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;smoothened signaling pathway#GO:0007224;intracellular signal transduction#GO:0035556;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;DNA damage response#GO:0006974;cell surface receptor signaling pathway#GO:0007166;apoptotic signaling pathway#GO:0097190;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007 membraneless organelle#GO:0043228;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;organelle lumen#GO:0043233 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016450.3|UniProtKB=A0A2I2ZLB7 A0A2I2ZLB7 CHTOP PTHR48426:SF1 CHROMATIN TARGET OF PRMT1 PROTEIN CHROMATIN TARGET OF PRMT1 PROTEIN sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 GORGO|Ensembl=ENSGGOG00000028092.2|UniProtKB=G3S6G5 G3S6G5 LOC101152650 PTHR12538:SF12 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008447.3|UniProtKB=G3RR76 G3RR76 TSHR PTHR24372:SF0 GLYCOPROTEIN HORMONE RECEPTOR THYROTROPIN RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000026128.2|UniProtKB=G3RR65 G3RR65 PITX3 PTHR45882:SF2 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010812.3|UniProtKB=G3R5G9 G3R5G9 CD151 PTHR19282:SF487 TETRASPANIN CD151 ANTIGEN cell migration#GO:0016477;cell motility#GO:0048870;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000675.3|UniProtKB=G3QEH0 G3QEH0 LOC101150995 PTHR47971:SF8 KINESIN-RELATED PROTEIN 6 KINESIN-LIKE PROTEIN KIF24 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microtubule motor activity#GO:0003777;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 microtubule depolymerization#GO:0007019;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;protein depolymerization#GO:0051261;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000006395.3|UniProtKB=G3QU59 G3QU59 IL12RB2 PTHR23036:SF79 CYTOKINE RECEPTOR INTERLEUKIN-12 RECEPTOR SUBUNIT BETA-2 cytokine receptor activity#GO:0004896;coreceptor activity#GO:0015026;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 GORGO|Ensembl=ENSGGOG00000012886.3|UniProtKB=A0A2I2YYE8 A0A2I2YYE8 NPC2 PTHR11306:SF68 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 2 binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934;alcohol binding#GO:0043178;steroid binding#GO:0005496;cholesterol binding#GO:0015485;lipid binding#GO:0008289 lipid transport#GO:0006869;intracellular sterol transport#GO:0032366;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cholesterol efflux#GO:0033344;localization#GO:0051179;establishment of localization#GO:0051234;sterol transport#GO:0015918;cellular localization#GO:0051641;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;intracellular transport#GO:0046907;transport#GO:0006810 GORGO|Ensembl=ENSGGOG00000009546.3|UniProtKB=G3SGY2 G3SGY2 RTCA PTHR11096:SF0 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;cyclase activity#GO:0009975 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000038847.1|UniProtKB=A0A2I2ZC01 A0A2I2ZC01 CENPO PTHR14582:SF1 INNER KINETOCHORE SUBUNIT MAL2 CENTROMERE PROTEIN O intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775 GORGO|Ensembl=ENSGGOG00000002897.3|UniProtKB=G3QK82 G3QK82 LGR5 PTHR24373:SF408 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008832.3|UniProtKB=G3R0F2 G3R0F2 MAP2K2 PTHR47448:SF3 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000042721.1|UniProtKB=A0A2I2YHN4 A0A2I2YHN4 LOC109028379 PTHR23115:SF222 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 1-RELATED catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000042056.1|UniProtKB=A0A2I2YXN0 A0A2I2YXN0 PTHR34930:SF4 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000041156.1|UniProtKB=G3SGP1 G3SGP1 LOC101146541 PTHR11736:SF37 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN D4 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000735.3|UniProtKB=G3QEM7 G3QEM7 LOC101136093 PTHR11467:SF42 HISTONE H1 HISTONE H1.8 binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;chromatin DNA binding#GO:0031490 negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000040690.1|UniProtKB=G3QT43 G3QT43 NDUFA13 PTHR12966:SF0 NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012543.3|UniProtKB=A0A2I2ZYK4 A0A2I2ZYK4 PIP5K1C PTHR23086:SF26 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 GAMMA catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transferase#PC00220;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000043186.1|UniProtKB=A0A2I2Y642 A0A2I2Y642 PTHR13946:SF30 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE RBP11-LIKE DIMERISATION DOMAIN-CONTAINING PROTEIN catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640 RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription#GO:0006351;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000003196.3|UniProtKB=A0A2I2ZS20 A0A2I2ZS20 GAS2L3 PTHR46756:SF7 TRANSGELIN GAS2-LIKE PROTEIN 3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000004313.4|UniProtKB=A0A2I2ZH41 A0A2I2ZH41 DOCK4 PTHR45653:SF7 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 4 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 response to external stimulus#GO:0009605;cell chemotaxis#GO:0060326;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;cell migration#GO:0016477;cell motility#GO:0048870;response to stimulus#GO:0050896;response to chemical#GO:0042221;taxis#GO:0042330;locomotion#GO:0040011;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000023588.2|UniProtKB=G3RZM7 G3RZM7 OCSTAMP PTHR21041:SF3 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN OSTEOCLAST STIMULATORY TRANSMEMBRANE PROTEIN hemopoiesis#GO:0030097;fertilization#GO:0009566;cell development#GO:0048468;reproductive process#GO:0022414;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;cellular process#GO:0009987;single fertilization#GO:0007338;leukocyte differentiation#GO:0002521;osteoclast differentiation#GO:0030316;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;developmental process#GO:0032502;sexual reproduction#GO:0019953 GORGO|Ensembl=ENSGGOG00000014261.3|UniProtKB=G3RED7 G3RED7 NUP153 PTHR23193:SF23 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP153 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236 organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014002.3|UniProtKB=G3RDQ3 G3RDQ3 MELTF PTHR11485:SF21 TRANSFERRIN MELANOTRANSFERRIN metal ion transport#GO:0030001;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 recycling endosome#GO:0055037;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endosome#GO:0005768;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000022843.2|UniProtKB=G3SC19 G3SC19 LRRN1 PTHR24366:SF46 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT NEURONAL 1 L HOMEOLOG PRECURSOR immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000012034.3|UniProtKB=G3R8M0 G3R8M0 PP2D1 PTHR13832:SF837 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000013715.3|UniProtKB=A0A2I2ZRN1 A0A2I2ZRN1 NPNT PTHR24050:SF19 PA14 DOMAIN-CONTAINING PROTEIN NEPHRONECTIN GORGO|Ensembl=ENSGGOG00000026430.2|UniProtKB=G3RZY5 G3RZY5 RLN2 PTHR12004:SF13 RELAXIN PRORELAXIN H2 peptide hormone#PC00179;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000000662.3|UniProtKB=G3QEF8 G3QEF8 BUD13 PTHR31809:SF0 BUD13 HOMOLOG BUD13 HOMOLOG RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000023634.2|UniProtKB=G3S690 G3S690 PTHR23266:SF346 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000025381.2|UniProtKB=G3RS66 G3RS66 LOC101130214 PTHR48026:SF20 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN RRM DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000003281.3|UniProtKB=G3QL76 G3QL76 HPDL PTHR11959:SF10 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE-LIKE PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000006735.3|UniProtKB=G3QV27 G3QV27 CYTL1 PTHR15974:SF0 CYTOKINE-LIKE PROTEIN 1 CYTOKINE-LIKE PROTEIN 1 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000004685.3|UniProtKB=G3QPT8 G3QPT8 DHRS1 PTHR44147:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000000461.3|UniProtKB=G3QDX4 G3QDX4 TCF20 PTHR14955:SF7 RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20 TRANSCRIPTION FACTOR 20 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000039279.1|UniProtKB=A0A2I2YMB8 A0A2I2YMB8 LOC101130137 PTHR24377:SF720 IP01015P-RELATED ZINC FINGER PROTEIN 570 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011683.3|UniProtKB=G3R7Q0 G3R7Q0 MTNR1A PTHR24228:SF53 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN RECEPTOR TYPE 1A molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000022102.2|UniProtKB=A0A2I2Y399 A0A2I2Y399 LOC101148624 PTHR47507:SF7 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793 GORGO|Ensembl=ENSGGOG00000006296.3|UniProtKB=G3QTX3 G3QTX3 PCGF1 PTHR10825:SF29 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 protein-containing complex#GO:0032991;PcG protein complex#GO:0031519;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000034809.2|UniProtKB=A0A2I2Y8U6 A0A2I2Y8U6 USP13 PTHR24006:SF682 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000015024.3|UniProtKB=G3RGC0 G3RGC0 WNT11 PTHR12027:SF7 WNT RELATED PROTEIN WNT-11 signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 signaling#GO:0023052;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell fate commitment#GO:0045165;system development#GO:0048731;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 GORGO|Ensembl=ENSGGOG00000010703.3|UniProtKB=A0A2I2ZAB6 A0A2I2ZAB6 LOC101133243 PTHR12764:SF4 WD REPEAT DOMAIN-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular localization#GO:0051641;non-motile cilium assembly#GO:1905515;localization#GO:0051179;cilium assembly#GO:0060271;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;protein localization to cilium#GO:0061512;microtubule-based movement#GO:0007018;protein localization to organelle#GO:0033365;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intraciliary transport particle#GO:0030990;cilium#GO:0005929;non-motile cilium#GO:0097730;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000016721.3|UniProtKB=G3RKN4 G3RKN4 LOC115936288 PTHR26453:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007907.3|UniProtKB=G3QY12 G3QY12 PTHR23235:SF21 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 13 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000034830.2|UniProtKB=G3SKH5 G3SKH5 SLC26A4 PTHR11814:SF33 SULFATE TRANSPORTER PENDRIN carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024921.2|UniProtKB=G3SHS6 G3SHS6 RNASE6 PTHR11437:SF4 RIBONUCLEASE RIBONUCLEASE K6 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518 defense response to Gram-positive bacterium#GO:0050830;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to Gram-negative bacterium#GO:0050829;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;defense response#GO:0006952;response to external stimulus#GO:0009605;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000008039.3|UniProtKB=A0A2I2Y821 A0A2I2Y821 RDH10 PTHR24322:SF755 PKSB RETINOL DEHYDROGENASE 10 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000028090.2|UniProtKB=G3S5W7 G3S5W7 PPOX PTHR42923:SF3 PROTOPORPHYRINOGEN OXIDASE PROTOPORPHYRINOGEN OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;oxidase#PC00175 Heme biosynthesis#P02746>Protoporphyrinogen oxidase#P02976 GORGO|Ensembl=ENSGGOG00000040043.1|UniProtKB=A0A2I2ZAE7 A0A2I2ZAE7 PTHR46756:SF11 TRANSGELIN CALPONIN binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;actin cytoskeleton organization#GO:0030036;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;actin filament-based process#GO:0030029;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;protein localization to microtubule cytoskeleton#GO:0072698;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;actin filament organization#GO:0007015;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule end#GO:1990752;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;actomyosin#GO:0042641;microtubule cytoskeleton#GO:0015630;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;stress fiber#GO:0001725;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000010444.3|UniProtKB=G3R4K4 G3R4K4 SLIT3 PTHR45836:SF9 SLIT HOMOLOG SLIT HOMOLOG 3 PROTEIN binding#GO:0005488;signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201;protein binding#GO:0005515 plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;locomotion#GO:0040011;system development#GO:0048731;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 GORGO|Ensembl=ENSGGOG00000043679.1|UniProtKB=A0A2I2ZEJ5 A0A2I2ZEJ5 NIT1 PTHR23088:SF27 NITRILASE-RELATED DEAMINATED GLUTATHIONE AMIDASE hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000014086.3|UniProtKB=G3RDY7 G3RDY7 DISC1 PTHR14332:SF3 DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;head development#GO:0060322;multicellular organismal process#GO:0032501;cell migration#GO:0016477;brain development#GO:0007420;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;neuron migration#GO:0001764;multicellular organism development#GO:0007275;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;cell motility#GO:0048870;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925 membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular membraneless organelle#GO:0043232;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794 GORGO|Ensembl=ENSGGOG00000003714.3|UniProtKB=G3QMB5 G3QMB5 HNRNPDL PTHR48033:SF2 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D-LIKE RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014376.3|UniProtKB=A0A2I2ZA05 A0A2I2ZA05 BACE1 PTHR47965:SF69 ASPARTYL PROTEASE-RELATED BETA-SECRETASE 1 catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;membrane protein proteolysis#GO:0033619;protein maturation#GO:0051604;gene expression#GO:0010467;membrane protein ectodomain proteolysis#GO:0006509;biosynthetic process#GO:0009058 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>Pro-BACE-1#P00081;Alzheimer disease-presenilin pathway#P00004>Pro-BACE-1#P00162;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1#P00101;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1 pro-domain#P00094;Alzheimer disease-presenilin pathway#P00004>BACE-1#P00172;Alzheimer disease-presenilin pathway#P00004>BACE-1 pro-domain#P00178 GORGO|Ensembl=ENSGGOG00000039339.1|UniProtKB=A0A2I2YPZ5 A0A2I2YPZ5 PTHR10732:SF14 40S RIBOSOMAL PROTEIN S17 SMALL RIBOSOMAL SUBUNIT PROTEIN ES17 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013014.3|UniProtKB=G3RB56 G3RB56 NTN5 PTHR10574:SF262 NETRIN/LAMININ-RELATED NETRIN-5 axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;anatomical structure development#GO:0048856;system development#GO:0048731;neuron projection development#GO:0031175;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;dendrite development#GO:0016358;neuron development#GO:0048666;axonogenesis#GO:0007409 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000022903.2|UniProtKB=G3SDI2 G3SDI2 LOC101150279 PTHR16675:SF242 MHC CLASS I-RELATED MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-RELATED PROTEIN 1 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000002943.3|UniProtKB=G3QKC0 G3QKC0 DEFB121 PTHR15001:SF8 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 121 cellular process#GO:0009987;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;cell killing#GO:0001906;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000026048.2|UniProtKB=A0A2I2YEJ7 A0A2I2YEJ7 PTHR11843:SF12 40S RIBOSOMAL PROTEIN S12 40S RIBOSOMAL PROTEIN S12 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;metabolic process#GO:0008152;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;translation#GO:0006412 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000014518.3|UniProtKB=G3RF05 G3RF05 MYOT PTHR10075:SF23 BASIGIN RELATED MYOTILIN cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000013247.3|UniProtKB=G3RBQ9 G3RBQ9 DAO PTHR11530:SF15 D-AMINO ACID OXIDASE D-AMINO-ACID OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000021984.2|UniProtKB=G3SHZ0 G3SHZ0 PTHR24249:SF220 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 4 G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;response to stress#GO:0006950;signaling#GO:0023052;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;defense response#GO:0006952;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000013594.3|UniProtKB=A0A2I2YFP1 A0A2I2YFP1 BOLL PTHR11176:SF10 BOULE-RELATED PROTEIN BOULE-LIKE translation regulator activity#GO:0045182 regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;regulation of translational initiation#GO:0006446;positive regulation of protein metabolic process#GO:0051247;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of catabolic process#GO:0009895;positive regulation of translation#GO:0045727;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of RNA stability#GO:0043487;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014326.3|UniProtKB=G3RNZ4 G3RNZ4 KIAA1958 PTHR46963:SF1 SIMILAR TO RIKEN CDNA E130308A19 KIAA1958 HOMOLOG GORGO|Ensembl=ENSGGOG00000026499.2|UniProtKB=G3SHQ6 G3SHQ6 PTHR37404:SF1 HCG1796489 STABILIZER OF AXONEMAL MICROTUBULES 3 GORGO|Ensembl=ENSGGOG00000010699.3|UniProtKB=G3R565 G3R565 PDE6A PTHR11347:SF115 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of cell communication#GO:0010646;visual system development#GO:0150063;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;eye development#GO:0001654;system development#GO:0048731;negative regulation of intracellular signal transduction#GO:1902532;anatomical structure development#GO:0048856;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;camera-type eye development#GO:0043010;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;retina development in camera-type eye#GO:0060041;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;sensory system development#GO:0048880;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423 ciliary membrane#GO:0060170;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;cilium#GO:0005929 phosphodiesterase#PC00185;hydrolase#PC00121 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEalphabeta#P00759 GORGO|Ensembl=ENSGGOG00000012445.3|UniProtKB=A0A2I2ZLV5 A0A2I2ZLV5 PTHR21223:SF4 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 1 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;ciliary transition zone#GO:0035869;cytoskeleton#GO:0005856;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000023152.2|UniProtKB=G3S9A6 G3S9A6 IPO8 PTHR10997:SF26 IMPORTIN-7, 8, 11 IMPORTIN-8 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 nucleus#GO:0005634;organelle envelope#GO:0031967;cytosol#GO:0005829;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003778.3|UniProtKB=A0A2I2Z150 A0A2I2Z150 TMEM131L PTHR22050:SF2 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131-LIKE negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of signal transduction#GO:0009968;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000013942.3|UniProtKB=G3S668 G3S668 PTHR21501:SF3 PROTEIN FAM-161 PROTEIN FAM161A cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;ciliary transition zone#GO:0035869 GORGO|Ensembl=ENSGGOG00000012737.3|UniProtKB=G3RAE9 G3RAE9 LOC101141797 PTHR24241:SF145 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005112.3|UniProtKB=G3SGQ4 G3SGQ4 UMOD PTHR46160:SF6 ALPHA-TECTORIN-RELATED UROMODULIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009536.3|UniProtKB=G3R282 G3R282 NCAPD2 PTHR14222:SF2 CONDENSIN CONDENSIN COMPLEX SUBUNIT 1 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;sexual reproduction#GO:0019953;nuclear division#GO:0000280;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensin complex#GO:0000796;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008895.3|UniProtKB=G3R0K8 G3R0K8 LOC101148752 PTHR11818:SF101 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN B structural molecule activity#GO:0005198 sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000011948.3|UniProtKB=G3R8E8 G3R8E8 PTHR10361:SF19 SODIUM-BILE ACID COTRANSPORTER ILEAL SODIUM_BILE ACID COTRANSPORTER symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081 lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;lipid transport#GO:0006869 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000002749.3|UniProtKB=G3QJV3 G3QJV3 TAFA3 PTHR31770:SF3 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-3 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 positive regulation of response to external stimulus#GO:0032103;positive regulation of leukocyte activation#GO:0002696;positive regulation of inflammatory response#GO:0050729;negative regulation of response to external stimulus#GO:0032102;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;regulation of macrophage activation#GO:0043030;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;negative regulation of cell activation#GO:0050866;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;negative regulation of inflammatory response#GO:0050728;regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;negative regulation of multicellular organismal process#GO:0051241 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;chemokine#PC00074 GORGO|Ensembl=ENSGGOG00000005251.3|UniProtKB=G3QRA5 G3QRA5 MTHFD1 PTHR48099:SF1 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000037119.1|UniProtKB=G3RXY3 G3RXY3 PTHR13218:SF15 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 11 LIKE PROTEIN 2-RELATED RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 GORGO|Ensembl=ENSGGOG00000001869.3|UniProtKB=A0A2I2Y6G7 A0A2I2Y6G7 SPATA22 PTHR35258:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 22 SPERMATOGENESIS-ASSOCIATED PROTEIN 22 regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of reproductive process#GO:2000241;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000012206.3|UniProtKB=G3R932 G3R932 PRRT3 PTHR47400:SF1 PROLINE-RICH TRANSMEMBRANE PROTEIN 3 PROLINE-RICH TRANSMEMBRANE PROTEIN 3 GORGO|Ensembl=ENSGGOG00000026444.2|UniProtKB=A0A2I2Y845 A0A2I2Y845 PTHR48026:SF2 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000024379.2|UniProtKB=G3SEW9 G3SEW9 TSC22D2 PTHR46894:SF1 TSC22 DOMAIN FAMILY PROTEIN 2 TSC22 DOMAIN FAMILY PROTEIN 2 GORGO|Ensembl=ENSGGOG00000010778.3|UniProtKB=G3R5J0 G3R5J0 MYCBP2 PTHR45943:SF1 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of synapse organization#GO:0050807;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of growth#GO:0040008;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;axon development#GO:0061564;axon guidance#GO:0007411 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000005780.3|UniProtKB=A0A2I2YP75 A0A2I2YP75 COPB2 PTHR19876:SF2 COATOMER COATOMER SUBUNIT BETA' localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193 intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;COPI-coated vesicle#GO:0030137;cytoplasm#GO:0005737;vesicle coat#GO:0030120 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000002628.3|UniProtKB=G3RYN2 G3RYN2 SMTN PTHR23167:SF52 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SMOOTHELIN actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008750.3|UniProtKB=G3R080 G3R080 FLT1 PTHR24416:SF390 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;vascular endothelial growth factor receptor signaling pathway#GO:0048010;positive regulation of cell motility#GO:2000147;blood vessel morphogenesis#GO:0048514;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of signaling#GO:0023051;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;angiogenesis#GO:0001525;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;tube development#GO:0035295;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of locomotion#GO:0040017;positive regulation of MAPK cascade#GO:0043410;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008987.3|UniProtKB=G3R0U1 G3R0U1 TSGA13 PTHR37352:SF1 TESTIS-SPECIFIC GENE 13 PROTEIN TESTIS-SPECIFIC GENE 13 PROTEIN GORGO|Ensembl=ENSGGOG00000034829.2|UniProtKB=G3SKS1 G3SKS1 PCNX2 PTHR12372:SF5 PECANEX PECANEX-LIKE PROTEIN 2 GORGO|Ensembl=ENSGGOG00000002096.3|UniProtKB=G3QI62 G3QI62 SCN2B PTHR13869:SF3 MYELIN P0 RELATED SODIUM CHANNEL REGULATORY SUBUNIT BETA-2 ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 heart contraction#GO:0060047;system process#GO:0003008;cardiac muscle cell contraction#GO:0086003;regulation of membrane potential#GO:0042391;muscle contraction#GO:0006936;regulation of system process#GO:0044057;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cardiac muscle cell action potential involved in contraction#GO:0086002;blood circulation#GO:0008015;actin filament-based movement#GO:0030048;cellular process#GO:0009987;regulation of biological quality#GO:0065008;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;regulation of heart contraction#GO:0008016;striated muscle contraction#GO:0006941;membrane depolarization#GO:0051899;actin-mediated cell contraction#GO:0070252;heart process#GO:0003015;muscle system process#GO:0003012;action potential#GO:0001508;regulation of biological process#GO:0050789 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;sodium channel complex#GO:0034706;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000006770.3|UniProtKB=A0A2I2Z2L9 A0A2I2Z2L9 CDC14A PTHR23339:SF77 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;organelle assembly#GO:0070925;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;regulation of mitotic cell cycle phase transition#GO:1901990;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000026498.2|UniProtKB=G3SAY8 G3SAY8 ZNF532 PTHR47222:SF3 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 532 GORGO|Ensembl=ENSGGOG00000016761.3|UniProtKB=G3RKS0 G3RKS0 FSCN3 PTHR10551:SF1 FASCIN FASCIN-3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;supramolecular fiber organization#GO:0097435;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cell migration#GO:0016477;cellular component assembly#GO:0022607 lamellipodium#GO:0030027;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;membraneless organelle#GO:0043228;ruffle#GO:0001726;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902;cell projection membrane#GO:0031253;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;filopodium#GO:0030175;axon#GO:0030424;intracellular organelle#GO:0043229;growth cone#GO:0030426 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000003689.3|UniProtKB=G3QM90 G3QM90 AADACL4 PTHR23024:SF603 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE-LIKE 4 membrane#GO:0016020;cellular anatomical structure#GO:0110165 deacetylase#PC00087 GORGO|Ensembl=ENSGGOG00000013167.3|UniProtKB=G3RBI7 G3RBI7 FAM90A1 PTHR16035:SF18 PROTEIN FAM90A1 PROTEIN FAM90A1 GORGO|Ensembl=ENSGGOG00000041133.1|UniProtKB=G3SBK7 G3SBK7 CCL27 PTHR12015:SF208 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 27 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000000493.3|UniProtKB=G3SDZ7 G3SDZ7 NEUROD2 PTHR19290:SF83 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000024829.2|UniProtKB=G3S9G8 G3S9G8 PTHR32217:SF2 LYMPHOCYTE ANTIGEN 6H LYMPHOCYTE ANTIGEN 6L GORGO|Ensembl=ENSGGOG00000041760.1|UniProtKB=A0A2I2ZFY2 A0A2I2ZFY2 PTHR19861:SF0 WD40 REPEAT PROTEIN SWD2 WD REPEAT-CONTAINING PROTEIN 82 binding#GO:0005488;chromatin binding#GO:0003682 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000010804.3|UniProtKB=G3R5F9 G3R5F9 KMT5A PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607 chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010086.3|UniProtKB=G3R3L4 G3R3L4 GAB2 PTHR45960:SF1 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 2 signaling adaptor activity#GO:0035591;protein binding#GO:0005515;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;binding#GO:0005488;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Grb2#P01148;EGF receptor signaling pathway#P00018>Gab#P00563 GORGO|Ensembl=ENSGGOG00000001566.3|UniProtKB=G3QGT2 G3QGT2 MCRS1 PTHR13233:SF0 MICROSPHERULE PROTEIN 1 MICROSPHERULE PROTEIN 1 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000016025.3|UniProtKB=G3RIW4 G3RIW4 PSME2 PTHR10660:SF6 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 2 peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of protein catabolic process#GO:0042176;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;regulation of mitotic cell cycle#GO:0007346;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 Cell cycle#P00013>Proteasome#P00480 GORGO|Ensembl=ENSGGOG00000017144.3|UniProtKB=G3RLR9 G3RLR9 CALHM4 PTHR32261:SF5 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 4 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000001060.3|UniProtKB=G3QFH6 G3QFH6 IFT172 PTHR15722:SF2 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intraciliary transport particle B#GO:0030992 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000036270.1|UniProtKB=A0A2I2Y2H1 A0A2I2Y2H1 C9H11orf87 PTHR31870:SF2 SI:DKEY-183I3.9-RELATED CHROMOSOME 11 OPEN READING FRAME 87 GORGO|Ensembl=ENSGGOG00000015635.3|UniProtKB=A0A2I2ZTB9 A0A2I2ZTB9 GUCD1 PTHR31400:SF1 GUANYLYL CYCLASE DOMAIN CONTAINING PROTEIN 1 GUCD1 PROTEIN GUCD1 guanylate cyclase#PC00114 GORGO|Ensembl=ENSGGOG00000003413.3|UniProtKB=G3QLJ7 G3QLJ7 LOC109026589 PTHR21636:SF2 PROTEIN DOK-7 PROTEIN DOK-7 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043;neuromuscular junction development#GO:0007528;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 GORGO|Ensembl=ENSGGOG00000000596.3|UniProtKB=G3S0L3 G3S0L3 BTBD8 PTHR22427:SF2 GH15728P BTB_POZ DOMAIN-CONTAINING PROTEIN 8 GORGO|Ensembl=ENSGGOG00000008369.3|UniProtKB=G3QZ80 G3QZ80 OTUD7A PTHR13367:SF9 UBIQUITIN THIOESTERASE OTU DOMAIN-CONTAINING PROTEIN 7A cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 post-translational protein modification#GO:0043687;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule catabolic process#GO:0009057 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000003275.3|UniProtKB=A0A2I2Y4J3 A0A2I2Y4J3 VCAM1 PTHR13771:SF14 INTERCELLULAR ADHESION MOLECULE VASCULAR CELL ADHESION PROTEIN 1 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell adhesion mediated by integrin#GO:0033627;leukocyte cell-cell adhesion#GO:0007159;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000016666.3|UniProtKB=G3RKK5 G3RKK5 GTF3C1 PTHR15180:SF1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;rRNA transcription#GO:0009303;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;transcription factor TFIIIC complex#GO:0000127 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000004621.3|UniProtKB=G3QPN0 G3QPN0 AP1M2 PTHR10529:SF234 AP COMPLEX SUBUNIT MU AP-1 COMPLEX SUBUNIT MU-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 establishment of localization#GO:0051234;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;intracellular vesicle#GO:0097708;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000009716.3|UniProtKB=G3R2N3 G3R2N3 CYP2F1 PTHR24300:SF275 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2F1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;binding#GO:0005488;tetrapyrrole binding#GO:0046906 icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000011573.3|UniProtKB=G3R7F1 G3R7F1 MORN3 PTHR46511:SF1 MORN REPEAT-CONTAINING PROTEIN 3 MORN REPEAT-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000016900.3|UniProtKB=G3RL51 G3RL51 PTHR11639:SF160 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A1 binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169 sarcoplasmic reticulum#GO:0016529;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;sarcoplasm#GO:0016528;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000008152.3|UniProtKB=G3QYN0 G3QYN0 SLC14A1 PTHR10464:SF5 UREA TRANSPORTER UREA TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810;nitrogen compound transport#GO:0071705 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023692.2|UniProtKB=G3SEC1 G3SEC1 PTHR23226:SF78 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 396 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006715.3|UniProtKB=G3QV10 G3QV10 SETD1B PTHR45814:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1B catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000016584.3|UniProtKB=G3RKB4 G3RKB4 CSRNP1 PTHR13580:SF10 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN 1 transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000013025.3|UniProtKB=G3RB73 G3RB73 KIF18B PTHR24115:SF414 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF18B plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 organelle localization#GO:0051640;nuclear division#GO:0000280;cellular component disassembly#GO:0022411;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;localization#GO:0051179;supramolecular fiber organization#GO:0097435;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;protein-containing complex disassembly#GO:0032984;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule polymerization or depolymerization#GO:0031109;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule depolymerization#GO:0007019;protein depolymerization#GO:0051261;chromosome localization#GO:0050000;cytoskeleton organization#GO:0007010 microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000005689.3|UniProtKB=A0A2I2Z9M8 A0A2I2Z9M8 ATG13 PTHR13430:SF4 AUTOPHAGY-RELATED PROTEIN 13 AUTOPHAGY-RELATED PROTEIN 13 enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887 vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;organelle assembly#GO:0070925;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036 protein kinase complex#GO:1902911;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;autophagosome#GO:0005776;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000006903.3|UniProtKB=G3QVI2 G3QVI2 GPX5 PTHR11592:SF127 GLUTATHIONE PEROXIDASE EPIDIDYMAL SECRETORY GLUTATHIONE PEROXIDASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to oxidative stress#GO:0034599 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016762.3|UniProtKB=A0A2I2ZQW0 A0A2I2ZQW0 TRPM1 PTHR13800:SF13 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 1 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000022652.2|UniProtKB=A0A2I2YG61 A0A2I2YG61 LOC101146907 PTHR23169:SF25 ENVOPLAKIN MICROTUBULE-ACTIN CROSS-LINKING FACTOR 1, ISOFORMS 1_2_3_4_5 regulation of cell-substrate adhesion#GO:0010810;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;response to wounding#GO:0009611;cellular component organization or biogenesis#GO:0071840;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;intermediate filament cytoskeleton organization#GO:0045104;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;wound healing#GO:0042060;regulation of cell-matrix adhesion#GO:0001952;regulation of cell junction assembly#GO:1901888;intermediate filament-based process#GO:0045103;regulation of microtubule-based process#GO:0032886 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;cytoskeleton#GO:0005856 intermediate filament binding protein#PC00130;intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000041750.1|UniProtKB=A0A2I2Z9B4 A0A2I2Z9B4 PTHR13343:SF15 CREG1 PROTEIN PROTEIN CREG2 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012347.3|UniProtKB=G3S8K9 G3S8K9 PIF1 PTHR23274:SF11 DNA HELICASE-RELATED ATP-DEPENDENT DNA HELICASE PIF1 helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 DNA helicase#PC00011 GORGO|Ensembl=ENSGGOG00000007767.3|UniProtKB=G3QXP6 G3QXP6 PTHR24064:SF34 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 20 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000023088.2|UniProtKB=A0A2I2YZU9 A0A2I2YZU9 PTHR23105:SF211 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN EL8 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011980.3|UniProtKB=A0A2I2YQF0 A0A2I2YQF0 PTHR10031:SF56 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, MITOCHONDRIAL ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000036718.1|UniProtKB=A0A2I2Y4N1 A0A2I2Y4N1 PRXL2C PTHR28630:SF34 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2C GORGO|Ensembl=ENSGGOG00000037825.1|UniProtKB=A0A2I2Z6V1 A0A2I2Z6V1 ZNF648 PTHR24399:SF11 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER PROTEIN 648 transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of multicellular organismal process#GO:0051239;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000002225.3|UniProtKB=A0A2I2YIN9 A0A2I2YIN9 HOXA10 PTHR45874:SF1 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-A10 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000000231.3|UniProtKB=G3QDB6 G3QDB6 KCNV2 PTHR11537:SF40 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY V MEMBER 2 ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;action potential#GO:0001508;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000005319.3|UniProtKB=G3QRF5 G3QRF5 SLC25A14 PTHR45618:SF20 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED BRAIN MITOCHONDRIAL CARRIER PROTEIN 1 monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;proton transmembrane transporter activity#GO:0015078 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular response to stress#GO:0080135;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000034953.2|UniProtKB=G3SKJ1 G3SKJ1 CCDC39 PTHR18962:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based transport#GO:0099111;inner dynein arm assembly#GO:0036159;cilium movement#GO:0003341;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;determination of bilateral symmetry#GO:0009855;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;left/right pattern formation#GO:0060972;microtubule-based movement#GO:0007018;cell motility#GO:0048870;determination of left/right symmetry#GO:0007368;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;pattern specification process#GO:0007389;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;multicellular organismal process#GO:0032501;regionalization#GO:0003002;plasma membrane bounded cell projection organization#GO:0120036;establishment of localization#GO:0051234;plasma membrane bounded cell projection assembly#GO:0120031;specification of symmetry#GO:0009799;developmental process#GO:0032502;transport#GO:0006810 membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000027757.2|UniProtKB=G3S8K3 G3S8K3 UBXN4 PTHR46424:SF1 UBX DOMAIN-CONTAINING PROTEIN 4 UBX DOMAIN-CONTAINING PROTEIN 4 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007465.3|UniProtKB=G3QWY4 G3QWY4 NT5DC1 PTHR12103:SF38 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 phosphatase#PC00181;hydrolase#PC00121;nucleotide phosphatase#PC00173 GORGO|Ensembl=ENSGGOG00000025100.3|UniProtKB=G3SIH5 G3SIH5 IQCM PTHR35978:SF1 IQ DOMAIN-CONTAINING PROTEIN M IQ DOMAIN-CONTAINING PROTEIN M GORGO|Ensembl=ENSGGOG00000000820.3|UniProtKB=G3RR01 G3RR01 NOS2 PTHR19384:SF56 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE, INDUCIBLE oxidoreductase activity, acting on NAD(P)H#GO:0016651;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;monooxygenase activity#GO:0004497;ribonucleotide binding#GO:0032553;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 biological regulation#GO:0065007;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;response to other organism#GO:0051707;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;regulation of blood pressure#GO:0008217;response to external stimulus#GO:0009605;system process#GO:0003008;defense response#GO:0006952;response to external biotic stimulus#GO:0043207;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;inflammatory response#GO:0006954;response to bacterium#GO:0009617;circulatory system process#GO:0003013;arginine metabolic process#GO:0006525;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;response to lipid#GO:0033993;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;response to stress#GO:0006950;response to lipopolysaccharide#GO:0032496;metabolic process#GO:0008152;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;small molecule catabolic process#GO:0044282;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;regulation of biological quality#GO:0065008;defense response to bacterium#GO:0042742;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 PI3 kinase pathway#P00048>NOS#P01205 GORGO|Ensembl=ENSGGOG00000001557.3|UniProtKB=G3QGS4 G3QGS4 PLA2G15 PTHR11440:SF47 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED LYSOSOMAL PHOSPHOLIPASE A AND ACYLTRANSFERASE carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;A2-type glycerophospholipase activity#GO:0004623 glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;ceramide metabolic process#GO:0006672;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000006762.3|UniProtKB=A0A2I2YDT1 A0A2I2YDT1 PPP3CA PTHR45673:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED PROTEIN PHOSPHATASE 3 CATALYTIC SUBUNIT ALPHA phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein binding#GO:0005515;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;calcineurin-mediated signaling#GO:0097720;calcineurin-NFAT signaling cascade#GO:0033173;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein phosphatase#PC00195 B cell activation#P00010>Calcineurin#P00386;Wnt signaling pathway#P00057>Calcineurin#P01446;T cell activation#P00053>Calcineurin#P01315;Gonadotropin-releasing hormone receptor pathway#P06664>Caln#P06728;CCKR signaling map#P06959>CaN#P07178 GORGO|Ensembl=ENSGGOG00000001757.3|UniProtKB=G3QHA7 G3QHA7 PTHR11203:SF11 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;binding#GO:0005488;nucleic acid binding#GO:0003676;exonuclease activity#GO:0004527;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;RNA binding#GO:0003723;hydrolase activity#GO:0016787 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000013576.3|UniProtKB=G3RCL1 G3RCL1 MMP9 PTHR10201:SF30 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-9 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Plasminogen activating cascade#P00050>pro-MMP-9#P01259;CCKR signaling map#P06959>MMP9#G06994;CCKR signaling map#P06959>MMP9#G07288;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000000758.3|UniProtKB=G3QEP8 G3QEP8 MEGF8 PTHR23244:SF511 KELCH REPEAT DOMAIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 8 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 GORGO|Ensembl=ENSGGOG00000012112.3|UniProtKB=G3R8T9 G3R8T9 ZNF780A PTHR24384:SF233 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 331 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000039817.1|UniProtKB=A0A2I2Z1X7 A0A2I2Z1X7 CRPPA PTHR43015:SF1 D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000017068.3|UniProtKB=G3SJZ3 G3SJZ3 ARID5A PTHR13964:SF25 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5A transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000001448.3|UniProtKB=G3SH21 G3SH21 JAKMIP3 PTHR18935:SF9 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000004903.3|UniProtKB=G3QQD9 G3QQD9 TCEANC PTHR11477:SF7 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A N-TERMINAL AND CENTRAL DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015746.3|UniProtKB=G3RI75 G3RI75 JAKMIP1 PTHR18935:SF6 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 1 protein binding#GO:0005515;GABA receptor binding#GO:0050811;binding#GO:0005488;signaling receptor binding#GO:0005102 GORGO|Ensembl=ENSGGOG00000036666.1|UniProtKB=G3R1L5 G3R1L5 ZNF696 PTHR24379:SF77 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 696 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000008291.3|UniProtKB=A0A2I2YW94 A0A2I2YW94 UMAD1 PTHR36291:SF1 UBAP1-MVB12-ASSOCIATED (UMA)-DOMAIN CONTAINING PROTEIN 1 UBAP1-MVB12-ASSOCIATED (UMA)-DOMAIN CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000009475.3|UniProtKB=G3SH93 G3SH93 NUP98 PTHR23198:SF6 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96 structural constituent of nuclear pore#GO:0017056;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;nucleic acid binding#GO:0003676 import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;protein localization to organelle#GO:0033365;establishment of RNA localization#GO:0051236;telomere localization#GO:0034397;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;chromosome localization#GO:0050000;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;cellular component organization#GO:0016043;cellular localization#GO:0051641;protein import into nucleus#GO:0006606;protein transport#GO:0015031;telomere tethering at nuclear periphery#GO:0034398 organelle envelope#GO:0031967;nucleus#GO:0005634;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000005174.3|UniProtKB=G3QR47 G3QR47 SNRNP200 PTHR24075:SF13 SEC63 DOMAIN-CONTAINING U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013708.3|UniProtKB=G3RCX6 G3RCX6 SAP25 PTHR39231:SF1 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP25 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP25 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000016971.3|UniProtKB=G3RLB5 G3RLB5 EDN2 PTHR13874:SF9 ENDOTHELIN ENDOTHELIN-2 G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515 inorganic ion homeostasis#GO:0098771;circulatory system process#GO:0003013;calcium ion homeostasis#GO:0055074;regulation of muscle contraction#GO:0006937;regulation of biological quality#GO:0065008;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;muscle system process#GO:0003012;intracellular monoatomic ion homeostasis#GO:0006873;regulation of muscle system process#GO:0090257;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;muscle contraction#GO:0006936;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;regulation of smooth muscle contraction#GO:0006940;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;system process#GO:0003008;intracellular calcium ion homeostasis#GO:0006874;positive regulation of biological process#GO:0048518;monoatomic ion homeostasis#GO:0050801;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Endothelin signaling pathway#P00019>ET1-4#P00588;Endothelin signaling pathway#P00019>Pro ET1-4#P00571;Endothelin signaling pathway#P00019>Big ET1-4#P00574;Endothelin signaling pathway#P00019>Pre-pro ET1-4#P00576 GORGO|Ensembl=ENSGGOG00000001952.3|UniProtKB=G3QHT6 G3QHT6 CCDC190 PTHR36871:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 GORGO|Ensembl=ENSGGOG00000011994.3|UniProtKB=G3R8J0 G3R8J0 ARRDC1 PTHR11188:SF182 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000028441.2|UniProtKB=A0A2I2YIW9 A0A2I2YIW9 BBX PTHR13059:SF10 HMG-BOX TRANSCRIPTION FACTOR BBX HMG BOX TRANSCRIPTION FACTOR BBX transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000022654.2|UniProtKB=A0A2I2Z9R2 A0A2I2Z9R2 PTHR10722:SF48 60S RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN EL19 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014659.3|UniProtKB=G3RFD4 G3RFD4 PTER PTHR10819:SF3 PHOSPHOTRIESTERASE-RELATED N-ACETYLTAURINE HYDROLASE esterase#PC00097;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000027839.2|UniProtKB=A0A2I2ZPW9 A0A2I2ZPW9 RPS9 PTHR11831:SF48 30S 40S RIBOSOMAL PROTEIN SMALL RIBOSOMAL SUBUNIT PROTEIN US4 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;RNA binding#GO:0003723;structural molecule activity#GO:0005198 ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000028222.2|UniProtKB=A0A2I2Z3D6 A0A2I2Z3D6 LOC101129478 PTHR26450:SF20 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007717.3|UniProtKB=G3QXK6 G3QXK6 BTBD2 PTHR24410:SF20 HL07962P-RELATED BTB DOMAIN CONTAINING 2 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000004660.3|UniProtKB=G3SD80 G3SD80 PTHR19277:SF94 PENTRAXIN NEURONAL PENTRAXIN RECEPTOR scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001022.3|UniProtKB=G3SEJ6 G3SEJ6 COL15A1 PTHR24023:SF912 COLLAGEN ALPHA COLLAGEN ALPHA-1(XV) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000041730.1|UniProtKB=A0A2I2ZEQ4 A0A2I2ZEQ4 PTHR24404:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 835 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000013655.3|UniProtKB=G3SIG4 G3SIG4 MAP1B PTHR13843:SF5 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1B actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of protein depolymerization#GO:1901879;neurogenesis#GO:0022008;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of microtubule-based process#GO:0032886;system development#GO:0048731;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;neuron projection development#GO:0031175;organelle organization#GO:0006996;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;dendrite development#GO:0016358;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128 cell body#GO:0044297;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;neuron projection#GO:0043005;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000026905.2|UniProtKB=G3S0S2 G3S0S2 GPR33 PTHR24225:SF5 CHEMOTACTIC RECEPTOR G PROTEIN-COUPLED RECEPTOR 33-RELATED immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of biological quality#GO:0065008;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000622.4|UniProtKB=G3QEC2 G3QEC2 PTHR48041:SF71 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sterol transfer activity#GO:0120015;cholesterol transfer activity#GO:0120020;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid transfer activity#GO:0120013 lipid transport#GO:0006869;cellular process#GO:0009987;cholesterol efflux#GO:0033344;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;sterol transport#GO:0015918;transport#GO:0006810;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;localization#GO:0051179;lipid localization#GO:0010876 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000012010.3|UniProtKB=G3SFE3 G3SFE3 PTHR26453:SF626 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015959.3|UniProtKB=G3RIQ9 G3RIQ9 SCML2 PTHR12247:SF84 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000037411.1|UniProtKB=G3S4Q2 G3S4Q2 XAGE2 PTHR14047:SF33 P ANTIGEN FAMILY MEMBER 5-RELATED X ANTIGEN FAMILY MEMBER 2 GORGO|Ensembl=ENSGGOG00000010389.3|UniProtKB=G3R4D3 G3R4D3 TSHB PTHR11515:SF5 GLYCOPROTEIN HORMONE BETA CHAIN THYROTROPIN SUBUNIT BETA hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Thyrotropin#P04588;Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585 GORGO|Ensembl=ENSGGOG00000007251.3|UniProtKB=A0A2I2YKV8 A0A2I2YKV8 LRIF1 PTHR16131:SF2 LIGAND-DEPENDENT NUCLEAR RECEPTOR-INTERACTING FACTOR 1 LIGAND-DEPENDENT NUCLEAR RECEPTOR-INTERACTING FACTOR 1 GORGO|Ensembl=ENSGGOG00000007803.3|UniProtKB=G3QXS4 G3QXS4 TMEM120B PTHR21433:SF2 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA TRANSMEMBRANE PROTEIN 120B cellular process#GO:0009987;developmental process#GO:0032502;fat cell differentiation#GO:0045444;cellular developmental process#GO:0048869;cell differentiation#GO:0030154 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011143.3|UniProtKB=G3R6C3 G3R6C3 CORIN PTHR24270:SF2 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED ATRIAL NATRIURETIC PEPTIDE-CONVERTING ENZYME regulation of blood pressure#GO:0008217;circulatory system process#GO:0003013;system process#GO:0003008;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;blood circulation#GO:0008015;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000028484.2|UniProtKB=G3RY80 G3RY80 C2CD4D PTHR46291:SF1 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4D GORGO|Ensembl=ENSGGOG00000023771.2|UniProtKB=G3RRF8 G3RRF8 LOC101142541 PTHR12021:SF11 THYMOSIN BETA THYMOSIN BETA-15A-RELATED cytoskeletal protein binding#GO:0008092;protein sequestering activity#GO:0140311;actin binding#GO:0003779;actin monomer binding#GO:0003785;molecular sequestering activity#GO:0140313;binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334 protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000001073.3|UniProtKB=G3QFI4 G3QFI4 OC90 PTHR11716:SF1 PHOSPHOLIPASE A2 FAMILY MEMBER OTOCONIN-90 phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000012570.3|UniProtKB=G3RA26 G3RA26 COL4A2 PTHR24023:SF588 COLLAGEN ALPHA COLLAGEN ALPHA-2(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;extracellular matrix organization#GO:0030198;enzyme-linked receptor protein signaling pathway#GO:0007167;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000009880.3|UniProtKB=G3R335 G3R335 NEFM PTHR45652:SF3 GLIAL FIBRILLARY ACIDIC PROTEIN NEUROFILAMENT MEDIUM POLYPEPTIDE structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intermediate filament cytoskeleton organization#GO:0045104;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;intermediate filament bundle assembly#GO:0045110;intermediate filament organization#GO:0045109 axon#GO:0030424;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;neuron projection#GO:0043005;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 cytoskeletal protein#PC00085;intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000006062.3|UniProtKB=G3QTB5 G3QTB5 CABYR PTHR15494:SF0 CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013819.3|UniProtKB=A0A2I2YZ17 A0A2I2YZ17 NTRK1 PTHR24416:SF370 TYROSINE-PROTEIN KINASE RECEPTOR HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cell differentiation#GO:0030154;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular response to nerve growth factor stimulus#GO:1990090;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007 signaling receptor complex#GO:0043235;axon#GO:0030424;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016814.3|UniProtKB=G3RKX6 G3RKX6 KCNH2 PTHR10217:SF506 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED INWARDLY RECTIFYING POTASSIUM CHANNEL KCNH2 potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000000973.3|UniProtKB=G3QF93 G3QF93 APCDD1 PTHR31021:SF2 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN APCDD1 protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488 regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000038983.1|UniProtKB=A0A2I2Z5Y4 A0A2I2Z5Y4 PTHR10317:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E N-TERMINAL DOMAIN-CONTAINING PROTEIN translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852 translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000006366.3|UniProtKB=G3SJ87 G3SJ87 P4HA2 PTHR10869:SF244 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012159.3|UniProtKB=G3R903 G3R903 LTBP1 PTHR24034:SF140 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 1 extracellular matrix binding#GO:0050840;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000003177.3|UniProtKB=G3RV32 G3RV32 SOX21 PTHR10270:SF313 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-21 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;head development#GO:0060322;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000009703.4|UniProtKB=G3R2N0 G3R2N0 THSD7B PTHR11311:SF7 SPONDIN THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7B actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000000252.3|UniProtKB=G3QDD5 G3QDD5 GAL PTHR16839:SF1 GALANIN GALANIN PEPTIDES signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;neuropeptide hormone activity#GO:0005184 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell body#GO:0044297;vesicle#GO:0031982;endomembrane system#GO:0012505;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;secretory vesicle#GO:0099503 GORGO|Ensembl=ENSGGOG00000012819.3|UniProtKB=G3RAP7 G3RAP7 PTHR46785:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B GORGO|Ensembl=ENSGGOG00000002868.3|UniProtKB=G3QK51 G3QK51 CENPN PTHR46790:SF1 CENTROMERE PROTEIN N CENTROMERE PROTEIN N membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000005549.3|UniProtKB=G3QS17 G3QS17 BEST2 PTHR10736:SF1 BESTROPHIN BESTROPHIN-2A monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 chloride transport#GO:0006821;transport#GO:0006810;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023945.2|UniProtKB=G3SJ32 G3SJ32 SPINK9 PTHR47499:SF2 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 9 peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of proteolysis#GO:0030162;negative regulation of cellular process#GO:0048523 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000014693.3|UniProtKB=A0A2I2Z2A6 A0A2I2Z2A6 METTL9 PTHR12890:SF0 DREV PROTEIN PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000009878.3|UniProtKB=G3R336 G3R336 HPGD PTHR44229:SF11 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;prostaglandin metabolic process#GO:0006693;unsaturated fatty acid metabolic process#GO:0033559;multicellular organismal process#GO:0032501;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;reproductive process#GO:0022414;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;multi-multicellular organism process#GO:0044706 extracellular region#GO:0005576;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Gene=HBG2|UniProtKB=P62742 P62742 HBG2 PTHR11442:SF89 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT GAMMA-2 heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515 cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;cell development#GO:0048468;localization#GO:0051179;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;developmental process#GO:0032502;transport#GO:0006810 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219;globin#PC00107 GORGO|Ensembl=ENSGGOG00000023122.2|UniProtKB=G3SHX6 G3SHX6 PTHR23266:SF379 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-3 binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000015164.3|UniProtKB=G3RWS5 G3RWS5 ZSCAN30 PTHR23226:SF128 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 30 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008165.3|UniProtKB=G3QYN6 G3QYN6 LOC101148386 PTHR26454:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012945.3|UniProtKB=G3RAZ9 G3RAZ9 PTHR23503:SF30 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 7 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 transport#GO:0006810;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000006122.3|UniProtKB=G3QTG9 G3QTG9 GRB2 PTHR19969:SF15 SH2-SH3 ADAPTOR PROTEIN-RELATED SRC-LIKE-ADAPTER 2 ISOFORM X1 receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025728.2|UniProtKB=G3RP83 G3RP83 PTHR24147:SF59 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 18B GORGO|Ensembl=ENSGGOG00000010184.3|UniProtKB=G3S004 G3S004 PANK2 PTHR12280:SF25 PANTOTHENATE KINASE PANTOTHENATE KINASE 2, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 GORGO|Ensembl=ENSGGOG00000007773.3|UniProtKB=G3QXQ3 G3QXQ3 SAXO5 PTHR34828:SF1 TESTIS-EXPRESSED PROTEIN 45 STABILIZER OF AXONEMAL MICROTUBULES 5 GORGO|Ensembl=ENSGGOG00000043553.1|UniProtKB=A0A2I2YDX5 A0A2I2YDX5 PTHR23268:SF92 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 3-1 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000005224.3|UniProtKB=A0A2I2YBE5 A0A2I2YBE5 KCNT1 PTHR10027:SF14 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000009398.3|UniProtKB=A0A2I2Z768 A0A2I2Z768 NCOR2 PTHR13992:SF21 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR NUCLEAR RECEPTOR COREPRESSOR 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 chromosome#GO:0005694;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 Notch signaling pathway#P00045>CoR#P01112;Huntington disease#P00029>N-CoR#P00770 GORGO|Ensembl=ENSGGOG00000022722.2|UniProtKB=A0A2I2ZEQ9 A0A2I2ZEQ9 PTHR12612:SF4 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 1 nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;localization#GO:0051179;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467 organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000024607.2|UniProtKB=G3RMC8 G3RMC8 ADIRF PTHR39227:SF1 ADIPOGENESIS REGULATORY FACTOR ADIPOGENESIS REGULATORY FACTOR regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of fat cell differentiation#GO:0045600;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000039919.1|UniProtKB=A0A2I2Z0K8 A0A2I2Z0K8 GPIHBP1 PTHR16983:SF12 UPAR/LY6 DOMAIN-CONTAINING PROTEIN GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED HIGH DENSITY LIPOPROTEIN-BINDING PROTEIN 1 protein-lipid complex binding#GO:0071814;enzyme binding#GO:0019899;lipoprotein particle binding#GO:0071813;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 lipid homeostasis#GO:0055088;triglyceride homeostasis#GO:0070328;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000011286.3|UniProtKB=G3R6P9 G3R6P9 SBNO2 PTHR12706:SF5 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH HOMOLOG 2 DNA binding#GO:0003677;protein binding#GO:0005515;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;histone binding#GO:0042393 regulation of defense response#GO:0031347;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;osteoclast differentiation#GO:0030316;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;immune system process#GO:0002376;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;myeloid cell differentiation#GO:0030099;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell development#GO:0048468;leukocyte activation involved in immune response#GO:0002366;negative regulation of RNA metabolic process#GO:0051253;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;cell activation#GO:0001775;regulation of inflammatory response#GO:0050727;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;leukocyte activation#GO:0045321;regulation of response to stress#GO:0080134;developmental process#GO:0032502;cellular developmental process#GO:0048869;macrophage activation#GO:0042116;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;hemopoiesis#GO:0030097;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;cell activation involved in immune response#GO:0002263;leukocyte differentiation#GO:0002521;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;immune effector process#GO:0002252;negative regulation of macromolecule biosynthetic process#GO:0010558;response to cytokine#GO:0034097;myeloid leukocyte activation#GO:0002274;response to chemical#GO:0042221 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000026917.2|UniProtKB=G3RXX6 G3RXX6 RPP30 PTHR13031:SF0 RIBONUCLEASE P SUBUNIT P30 RIBONUCLEASE P PROTEIN SUBUNIT P30 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;multimeric ribonuclease P complex#GO:0030681;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleolar ribonuclease P complex#GO:0005655;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 endoribonuclease#PC00094;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036855.1|UniProtKB=A0A2I2ZH62 A0A2I2ZH62 NABP1 PTHR13356:SF5 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 recombinational repair#GO:0000725;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;regulation of cell cycle G2/M phase transition#GO:1902749;response to radiation#GO:0009314;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;response to abiotic stimulus#GO:0009628;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000007973.3|UniProtKB=G3QY75 G3QY75 ANKS1A PTHR24174:SF4 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 1A protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;ephrin receptor signaling pathway#GO:0048013;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000036967.1|UniProtKB=A0A2I2Z696 A0A2I2Z696 THAP2 PTHR47696:SF1 THAP DOMAIN-CONTAINING PROTEIN 2 THAP DOMAIN-CONTAINING PROTEIN 2 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000004290.3|UniProtKB=A0A2I2YQ07 A0A2I2YQ07 PARPBP PTHR32121:SF0 PCNA-INTERACTING PARTNER PCNA-INTERACTING PARTNER regulation of macromolecule metabolic process#GO:0060255;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;negative regulation of double-strand break repair via homologous recombination#GO:2000042;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Gene=1B02_GORGO|UniProtKB=P30380 P30380 PTHR16675:SF279 MHC CLASS I-RELATED CLASS I HISTOCOMPATIBILITY ANTIGEN, GOGO-B*0102 ALPHA CHAIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823;peptide binding#GO:0042277 biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000007405.3|UniProtKB=G3QWT0 G3QWT0 CYSRT1 PTHR37879:SF1 CYSTEINE-RICH TAIL PROTEIN 1 CYSTEINE-RICH TAIL PROTEIN 1 GORGO|Ensembl=ENSGGOG00000005995.3|UniProtKB=G3QT54 G3QT54 FBXL12 PTHR16134:SF153 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 12 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012265.3|UniProtKB=A0A2I2YCP6 A0A2I2YCP6 SNAP25 PTHR19305:SF5 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 25 protein binding#GO:0005515;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905;binding#GO:0005488;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;synaptic vesicle membrane organization#GO:0048499;membrane fusion#GO:0061025;cellular localization#GO:0051641;secretion by cell#GO:0032940;signaling#GO:0023052;export from cell#GO:0140352;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;exocytosis#GO:0006887;regulated exocytosis#GO:0045055;vesicle fusion to plasma membrane#GO:0099500;exocytic process#GO:0140029;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079 intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886 membrane traffic protein#PC00150;SNARE protein#PC00034 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Synaptic vesicle trafficking#P05734>SNAP-25#P05778;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996 GORGO|Ensembl=ENSGGOG00000004703.3|UniProtKB=G3QPV3 G3QPV3 DNAJB6 PTHR43948:SF6 DNAJ HOMOLOG SUBFAMILY B DNAJ HOMOLOG SUBFAMILY B MEMBER 6 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Gene=PRSS12|UniProtKB=Q5G270 Q5G270 PRSS12 PTHR48071:SF5 SRCR DOMAIN-CONTAINING PROTEIN NEUROTRYPSIN catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;zymogen activation#GO:0031638;primary metabolic process#GO:0044238 dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuron projection terminus#GO:0044306;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;terminal bouton#GO:0043195;cell junction#GO:0030054;axon terminus#GO:0043679;glutamatergic synapse#GO:0098978;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;neuron projection#GO:0043005;presynapse#GO:0098793;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000003483.3|UniProtKB=A0A2I2ZWY1 A0A2I2ZWY1 KLHDC4 PTHR46063:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000023848.2|UniProtKB=G3RXL1 G3RXL1 PTHR47904:SF1 NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;lymphocyte activation#GO:0046649;cell surface receptor signaling pathway#GO:0007166;natural killer cell activation#GO:0030101;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;positive regulation of immune effector process#GO:0002699;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of natural killer cell mediated cytotoxicity#GO:0042269;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;regulation of natural killer cell mediated immunity#GO:0002715;cellular response to stimulus#GO:0051716;regulation of leukocyte mediated immunity#GO:0002703;leukocyte activation#GO:0045321;positive regulation of natural killer cell mediated immunity#GO:0002717;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of defense response#GO:0031347;cell activation#GO:0001775;regulation of immune response#GO:0050776;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;cell communication#GO:0007154;positive regulation of lymphocyte mediated immunity#GO:0002708 GORGO|Ensembl=ENSGGOG00000005710.3|UniProtKB=G3QSF9 G3QSF9 AP5M1 PTHR16082:SF2 AP-5 COMPLEX SUBUNIT MU-1 AP-5 COMPLEX SUBUNIT MU-1 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;lysosome#GO:0005764;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;lytic vacuole#GO:0000323;AP-type membrane coat adaptor complex#GO:0030119 GORGO|Ensembl=ENSGGOG00000024822.2|UniProtKB=G3RNY6 G3RNY6 FZD3 PTHR11309:SF22 FRIZZLED FRIZZLED-3 Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;non-canonical Wnt signaling pathway#GO:0035567;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>Frizzled#P00475;Angiogenesis#P00005>Fzd#P00189;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Angiogenesis#P00005>FRP#P00237;Wnt signaling pathway#P00057>Frizzled#P01428 GORGO|Ensembl=ENSGGOG00000001720.3|UniProtKB=G3QH71 G3QH71 RIBC2 PTHR14517:SF10 RIB43A-RELATED RIB43A-LIKE WITH COILED-COILS PROTEIN 2 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000002488.3|UniProtKB=G3QJ65 G3QJ65 ZNF655 PTHR24381:SF458 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 697 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000010445.3|UniProtKB=G3R4J2 G3R4J2 NCAPH PTHR13108:SF9 CONDENSIN COMPLEX SUBUNIT 2 CONDENSIN COMPLEX SUBUNIT 2 chromatin binding#GO:0003682;binding#GO:0005488 organelle fission#GO:0048285;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;chromosome segregation#GO:0007059;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987 chromosome#GO:0005694;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;condensin complex#GO:0000796;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009040.3|UniProtKB=G3SEB3 G3SEB3 MYO1C PTHR13140:SF255 MYOSIN UNCONVENTIONAL MYOSIN-IC isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based movement#GO:0030048;cellular component organization#GO:0016043;organelle organization#GO:0006996 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000039026.1|UniProtKB=A0A2I2ZGW9 A0A2I2ZGW9 OMG PTHR47114:SF2 FAMILY NOT NAMED OLIGODENDROCYTE-MYELIN GLYCOPROTEIN cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;regeneration#GO:0031099;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;response to stress#GO:0006950;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular response to stress#GO:0033554;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716 GORGO|Ensembl=ENSGGOG00000042860.1|UniProtKB=A0A2I2Y5A0 A0A2I2Y5A0 LOC101137162 PTHR13313:SF1 CYTOCHROME C OXIDASE SUBUNIT VIIC CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775 transporter complex#GO:1990351;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000027521.2|UniProtKB=G3RWG0 G3RWG0 INAVA PTHR16093:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 120 FAMILY MEMBER INNATE IMMUNITY ACTIVATOR PROTEIN cell-cell junction organization#GO:0045216;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399;cellular component organization or biogenesis#GO:0071840;cell-cell junction maintenance#GO:0045217;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of biological process#GO:0050789;adherens junction organization#GO:0034332;regulation of protein modification by small protein conjugation or removal#GO:1903320;cellular component organization#GO:0016043;regulation of macromolecule metabolic process#GO:0060255;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794 GORGO|Ensembl=ENSGGOG00000016943.3|UniProtKB=G3RL95 G3RL95 MEIG1 PTHR17008:SF1 MEIOSIS-EXPRESSED GENE 1 PROTEIN MEIOSIS EXPRESSED GENE 1 PROTEIN HOMOLOG reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002850.3|UniProtKB=G3QK39 G3QK39 ETS1 PTHR11849:SF314 ETS PROTEIN C-ETS-1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Angiogenesis#P00005>Ets#P00188;Ras Pathway#P04393>Ets#P04563;PDGF signaling pathway#P00047>Ets#P01167;VEGF signaling pathway#P00056>Ets#P01419 GORGO|Ensembl=ENSGGOG00000000374.3|UniProtKB=G3QDP4 G3QDP4 GABBR2 PTHR10519:SF74 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;regulation of biological process#GO:0050789 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 GORGO|Ensembl=ENSGGOG00000015787.3|UniProtKB=G3RIB2 G3RIB2 PKN1 PTHR24356:SF246 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 GORGO|Ensembl=ENSGGOG00000009725.3|UniProtKB=A0A2I2Z1H8 A0A2I2Z1H8 SLC8B1 PTHR12266:SF39 NA+/CA2+ K+ INDEPENDENT EXCHANGER MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000009770.3|UniProtKB=G3R2U4 G3R2U4 ARHGAP4 PTHR14166:SF16 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 4 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;multicellular organism development#GO:0007275;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;GTPase-activating protein#PC00257 CCKR signaling map#P06959>ARHGAP4#P07135;PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000014117.3|UniProtKB=G3RE08 G3RE08 IL9 PTHR16926:SF1 INTERLEUKIN 9 INTERLEUKIN-9 signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;cytokine#PC00083;interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970 GORGO|Ensembl=ENSGGOG00000000174.3|UniProtKB=G3QD63 G3QD63 MARCHF4 PTHR46053:SF3 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF4 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000009097.3|UniProtKB=G3R141 G3R141 PTHR46105:SF6 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Gene=SRY|UniProtKB=P48046 P48046 SRY PTHR10270:SF336 SOX TRANSCRIPTION FACTOR SEX-DETERMINING REGION Y PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;developmental process involved in reproduction#GO:0003006;positive regulation of RNA metabolic process#GO:0051254;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000008938.3|UniProtKB=G3QM48 G3QM48 TTYH3 PTHR12424:SF4 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 3 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010007.3|UniProtKB=G3R3E4 G3R3E4 PIGR PTHR11860:SF82 POLYMERIC-IMMUNOGLOBULIN RECEPTOR POLYMERIC IMMUNOGLOBULIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008933.3|UniProtKB=A0A2I2YF51 A0A2I2YF51 PTHR23320:SF177 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040592.1|UniProtKB=A0A2I2Z4I2 A0A2I2Z4I2 PTHR24291:SF220 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F3 small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;arachidonate metabolic process#GO:0019369;ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;vitamin K metabolic process#GO:0042373;monocarboxylic acid metabolic process#GO:0032787;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000013547.3|UniProtKB=A0A2I2Z814 A0A2I2Z814 LOC101134045 PTHR19370:SF108 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 2 heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 reductase#PC00198;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003553.3|UniProtKB=A0A2I2ZSW9 A0A2I2ZSW9 ERI3 PTHR23044:SF85 3'-5' EXONUCLEASE ERI1-RELATED ERI1 EXORIBONUCLEASE 3 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;positive regulation of biosynthetic process#GO:0009891;regulation of chromatin organization#GO:1902275;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000015144.3|UniProtKB=G3RGM9 G3RGM9 ZNF687 PTHR47222:SF2 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 687 GORGO|Ensembl=ENSGGOG00000016580.3|UniProtKB=A0A2I2ZC96 A0A2I2ZC96 GLS2 PTHR12544:SF33 GLUTAMINASE GLUTAMINASE LIVER ISOFORM, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000009711.3|UniProtKB=G3R2N6 G3R2N6 SPAG5 PTHR15347:SF1 SPERM-ASSOCIATED ANTIGEN 5 SPERM-ASSOCIATED ANTIGEN 5 GORGO|Ensembl=ENSGGOG00000000078.3|UniProtKB=G3RWA6 G3RWA6 SRGAP1 PTHR14166:SF15 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 1 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;regulation of locomotion#GO:0040012;nervous system development#GO:0007399;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;developmental process#GO:0032502;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;animal gross anatomical part developmental process#GO:0160108;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;system development#GO:0048731;regulation of biological quality#GO:0065008 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174;Axon guidance mediated by Slit/Robo#P00008>SrGAP#P00350 GORGO|Ensembl=ENSGGOG00000000044.3|UniProtKB=G3SIF3 G3SIF3 HSH2D PTHR14388:SF3 T CELL-SPECIFIC ADAPTER PROTEIN TSAD HEMATOPOIETIC SH2 DOMAIN-CONTAINING PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000066.4|UniProtKB=G3QCW3 G3QCW3 GADL1 PTHR45677:SF1 GLUTAMATE DECARBOXYLASE-RELATED ACIDIC AMINO ACID DECARBOXYLASE GADL1 lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 GORGO|Ensembl=ENSGGOG00000017121.3|UniProtKB=G3RLQ2 G3RLQ2 HSCB PTHR14021:SF20 IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000009761.3|UniProtKB=G3R2S3 G3R2S3 TIMP4 PTHR11844:SF26 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 4 endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;response to cytokine#GO:0034097;response to chemical#GO:0042221;negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of catabolic process#GO:0009895;response to peptide#GO:1901652;regulation of protein catabolic process#GO:0042176;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000012625.3|UniProtKB=G3RA55 G3RA55 DPEP3 PTHR10443:SF14 MICROSOMAL DIPEPTIDASE DIPEPTIDASE 3 catalytic activity#GO:0003824;peptidase activity#GO:0008233;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015018.3|UniProtKB=G3RGB6 G3RGB6 XYLB PTHR10196:SF57 SUGAR KINASE XYLULOSE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 kinase#PC00137;carbohydrate kinase#PC00065 Ascorbate degradation#P02729>L-xylulose kinase#P02849 GORGO|Ensembl=ENSGGOG00000042619.1|UniProtKB=A0A2I2YK49 A0A2I2YK49 BATF3 PTHR23351:SF13 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE 3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000007754.3|UniProtKB=G3QXN8 G3QXN8 CAPN1 PTHR10183:SF284 CALPAIN CALPAIN-1 CATALYTIC SUBUNIT cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000009118.3|UniProtKB=G3R154 G3R154 FFAR1 PTHR45822:SF4 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;bioactive lipid receptor activity#GO:0045125 positive regulation of protein secretion#GO:0050714;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of insulin secretion#GO:0050796;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;response to lipid#GO:0033993;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of secretion#GO:0051047;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;regulation of hormone secretion#GO:0046883;positive regulation of signaling#GO:0023056;regulation of protein localization#GO:0032880;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;response to stimulus#GO:0050896;regulation of protein transport#GO:0051223;signaling#GO:0023052;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of hormone secretion#GO:0046887;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of establishment of protein localization#GO:0070201;response to fatty acid#GO:0070542;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000043876.1|UniProtKB=A0A2I2YF56 A0A2I2YF56 PTHR10943:SF15 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;endopeptidase complex#GO:1905369 protease#PC00190 GORGO|Ensembl=ENSGGOG00000000419.3|UniProtKB=A0A2I2Y3B9 A0A2I2Y3B9 GTF2IRD1 PTHR46304:SF3 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1 GTF2I REPEAT DOMAIN CONTAINING 1 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000010621.3|UniProtKB=G3R500 G3R500 PTHR18916:SF10 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 2 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;cell cortex#GO:0005938;microtubule end#GO:1990752;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000038950.1|UniProtKB=A0A2I2YG85 A0A2I2YG85 LOC101130894 PTHR13946:SF47 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleic acid biosynthetic process#GO:0141187;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000037384.1|UniProtKB=G3QWG7 G3QWG7 RRP36 PTHR21738:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000003632.3|UniProtKB=G3QM46 G3QM46 SSC5D PTHR19331:SF487 SCAVENGER RECEPTOR DOMAIN-CONTAINING SOLUBLE SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN SSC5D cargo receptor activity#GO:0038024 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000015668.3|UniProtKB=G3RI04 G3RI04 PTHR23095:SF45 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 8B transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000043695.1|UniProtKB=G3RK01 G3RK01 TEF PTHR11988:SF24 THYROTROPH EMBRYONIC FACTOR RELATED THYROTROPH EMBRYONIC FACTOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000039428.1|UniProtKB=A0A2I2ZIG6 A0A2I2ZIG6 PTHR10969:SF20 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN binding#GO:0005488;signaling receptor binding#GO:0005102;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;GABA receptor binding#GO:0050811;phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625 process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;organelle organization#GO:0006996 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;autophagosome#GO:0005776;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;organelle membrane#GO:0031090 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000012143.3|UniProtKB=G3R8Y2 G3R8Y2 PEPD PTHR43226:SF1 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO DIPEPTIDASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000024970.2|UniProtKB=A0A2I2ZG60 A0A2I2ZG60 CEP43 PTHR15431:SF9 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 43 intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040962.1|UniProtKB=A0A2I2YPN7 A0A2I2YPN7 PTHR11239:SF12 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000016306.3|UniProtKB=G3RJN5 G3RJN5 ACO1 PTHR11670:SF32 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER CYTOPLASMIC ACONITATE HYDRATASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536;lyase activity#GO:0016829;RNA binding#GO:0003723 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;carboxylic acid metabolic process#GO:0019752;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular process#GO:0009987;intracellular iron ion homeostasis#GO:0006879;small molecule metabolic process#GO:0044281;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 GORGO|Ensembl=ENSGGOG00000024915.2|UniProtKB=G3RVL2 G3RVL2 GPRIN1 PTHR15718:SF7 G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH C-TERMINAL DOMAIN-CONTAINING PROTEIN G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 1 neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular component organization#GO:0016043 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000028200.2|UniProtKB=G3S6V6 G3S6V6 KLHL15 PTHR45632:SF12 LD33804P KELCH-LIKE PROTEIN 15 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;negative regulation of DNA recombination#GO:0045910;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;regulation of double-strand break repair#GO:2000779;cellular response to topologically incorrect protein#GO:0035967;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;cellular response to misfolded protein#GO:0071218;response to stimulus#GO:0050896;regulation of double-strand break repair via homologous recombination#GO:0010569;negative regulation of metabolic process#GO:0009892;response to topologically incorrect protein#GO:0035966;response to misfolded protein#GO:0051788;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular response to stress#GO:0080135;regulation of DNA recombination#GO:0000018;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of double-strand break repair via homologous recombination#GO:2000042 ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016268.3|UniProtKB=G3RJI0 G3RJI0 CEP170 PTHR15715:SF17 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 microtubule-based process#GO:0007017;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule anchoring#GO:0034453;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001353.3|UniProtKB=G3QG83 G3QG83 PPP1R15B PTHR16489:SF11 GH11727P PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;response to stress#GO:0006950 endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000007019.3|UniProtKB=G3QVT9 G3QVT9 ARHGAP26 PTHR12552:SF4 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 26 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174;Integrin signalling pathway#P00034>GRAF#P00926 GORGO|Ensembl=ENSGGOG00000008061.3|UniProtKB=G3QYF2 G3QYF2 CPZ PTHR11532:SF63 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE Z peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 GORGO|Ensembl=ENSGGOG00000005512.3|UniProtKB=A0A2I2Y6T3 A0A2I2Y6T3 AGAP1 PTHR45819:SF1 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000026357.2|UniProtKB=G3S6S1 G3S6S1 PRDX6 PTHR43503:SF11 MCG48959-RELATED PEROXIREDOXIN-6 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;peroxidase#PC00180 GORGO|Ensembl=ENSGGOG00000023142.2|UniProtKB=A0A2I2ZIJ8 A0A2I2ZIJ8 ZDBF2 PTHR21639:SF5 DBF4-TYPE ZINC FINGER-CONTAINING PROTEIN 2 DBF4-TYPE ZINC FINGER-CONTAINING PROTEIN 2 biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;developmental process#GO:0032502;gamete generation#GO:0007276;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;chromatin remodeling#GO:0006338;reproductive process#GO:0022414;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;germ cell development#GO:0007281;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953 GORGO|Ensembl=ENSGGOG00000003710.3|UniProtKB=G3QMB0 G3QMB0 GRHPR PTHR10996:SF137 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000037892.1|UniProtKB=G3RAM5 G3RAM5 LOC101145065 PTHR23239:SF396 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 17 structural molecule activity#GO:0005198 tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;skin development#GO:0043588;organelle organization#GO:0006996;cellular process#GO:0009987;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;epidermis development#GO:0008544;developmental process#GO:0032502;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109 supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000010426.3|UniProtKB=G3R4G7 G3R4G7 TRIM68 PTHR24103:SF89 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM68 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000027285.2|UniProtKB=G3S3Z4 G3S3Z4 PTHR44873:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000005272.3|UniProtKB=G3QRC2 G3QRC2 HAPLN3 PTHR22804:SF40 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 3 central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;system development#GO:0048731 cell periphery#GO:0071944;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;membrane#GO:0016020;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell junction#GO:0030054 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000009200.3|UniProtKB=G3R1D0 G3R1D0 LOC101127832 PTHR26452:SF836 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043610.1|UniProtKB=A0A2I2YAF9 A0A2I2YAF9 UBTD2 PTHR13609:SF20 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED UBIQUITIN DOMAIN-CONTAINING PROTEIN 2 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000037708.1|UniProtKB=A0A2I2ZY31 A0A2I2ZY31 TAGLN2 PTHR47385:SF20 CALPONIN TRANSGELIN-2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 GORGO|Ensembl=ENSGGOG00000000309.3|UniProtKB=G3QDI5 G3QDI5 PLPP3 PTHR10165:SF79 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 3 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 cell adhesion#GO:0007155;dephosphorylation#GO:0016311;cell communication#GO:0007154;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258;signal transduction#GO:0007165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000010396.3|UniProtKB=G3R4E0 G3R4E0 SERBP1 PTHR12299:SF29 HYALURONIC ACID-BINDING PROTEIN 4 SERPINE1 MRNA-BINDING PROTEIN 1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000028030.2|UniProtKB=G3RW99 G3RW99 NCCRP1 PTHR12125:SF1 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 50 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000021958.2|UniProtKB=A0A2I2ZW06 A0A2I2ZW06 YTHDC1 PTHR12357:SF3 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517;RNA binding#GO:0003723 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000043362.1|UniProtKB=A0A2I2YHI3 A0A2I2YHI3 LOC101138856 PTHR46259:SF3 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000005783.3|UniProtKB=G3QSL7 G3QSL7 LOC101138548 PTHR26454:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6S1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000024188.2|UniProtKB=G3RWM7 G3RWM7 C1QTNF3 PTHR48228:SF8 SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE ALPHA-METHYLACYL-COA RACEMASE isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;steroid metabolic process#GO:0008202;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;transferase#PC00220 Carnitine metabolism#P02733>Carnitine dehydratase#P02866;Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864 GORGO|Ensembl=ENSGGOG00000040593.1|UniProtKB=A0A2I2ZSU8 A0A2I2ZSU8 LOC109026312 PTHR13391:SF1 MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO PROTEIN MISATO HOMOLOG 1 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000000032.3|UniProtKB=A1YEQ3 A1YEQ3 ZNF449 PTHR23226:SF4 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 449 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014257.3|UniProtKB=G3RYC2 G3RYC2 PAMR1 PTHR24254:SF9 PROTHROMBIN INACTIVE SERINE PROTEASE PAMR1 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000013980.3|UniProtKB=G3RDN6 G3RDN6 PTHR23412:SF15 STEREOCILIN RELATED MESOTHELIN-LIKE PROTEIN cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000005652.3|UniProtKB=G3QSB9 G3QSB9 VPS35L PTHR13673:SF0 ESOPHAGEAL CANCER ASSOCIATED PROTEIN VPS35 ENDOSOMAL PROTEIN-SORTING FACTOR-LIKE vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007750.3|UniProtKB=G3QXN1 G3QXN1 SMYD5 PTHR46402:SF2 SET AND MYND DOMAIN-CONTAINING PROTEIN 5 PROTEIN-LYSINE N-TRIMETHYLTRANSFERASE SMYD5 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468 GORGO|Ensembl=ENSGGOG00000016774.3|UniProtKB=G3RKT3 G3RKT3 TSPAN8 PTHR19282:SF380 TETRASPANIN TETRASPANIN-8 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000024406.2|UniProtKB=G3QMT9 G3QMT9 PTHR11414:SF22 CYSTATIN FAMILY MEMBER CYSTATIN-B enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000013721.3|UniProtKB=G3RCZ2 G3RCZ2 KCTD2 PTHR14958:SF22 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD2 protein binding#GO:0005515;binding#GO:0005488 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000043304.1|UniProtKB=A0A2I2YZV2 A0A2I2YZV2 PTHR11431:SF93 FERRITIN FERRITIN iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914 transition metal ion transport#GO:0000041;transport#GO:0006810;iron ion transport#GO:0006826;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;metal ion transport#GO:0030001 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000013347.3|UniProtKB=G3RC06 G3RC06 TRIM28 PTHR25462:SF308 BONUS, ISOFORM C-RELATED TRANSCRIPTION INTERMEDIARY FACTOR 1-BETA transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;chromatin binding#GO:0003682;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;immune response#GO:0006955;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;response to other organism#GO:0051707;post-translational protein modification#GO:0043687;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;cellular process#GO:0009987;defense response to other organism#GO:0098542;metabolic process#GO:0008152;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;protein sumoylation#GO:0016925;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;negative regulation of metabolic process#GO:0009892;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000022927.2|UniProtKB=A0A2I2ZQT7 A0A2I2ZQT7 PTHR10660:SF6 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 2 peptidase regulator activity#GO:0061134;peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;endopeptidase regulator activity#GO:0061135;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of protein catabolic process#GO:0042176;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of mitotic cell cycle#GO:0007346;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 Cell cycle#P00013>Proteasome#P00480 GORGO|Ensembl=ENSGGOG00000012918.3|UniProtKB=A0A2I2ZN38 A0A2I2ZN38 EIF4A3 PTHR47958:SF26 ATP-DEPENDENT RNA HELICASE DBP3 EUKARYOTIC INITIATION FACTOR 4A-III catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000000926.3|UniProtKB=G3SFY0 G3SFY0 KANK3 PTHR24168:SF23 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 3 negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;regulation of biological quality#GO:0065008;negative regulation of protein polymerization#GO:0032272;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000043497.1|UniProtKB=A0A2I2YGM2 A0A2I2YGM2 PTHR23266:SF246 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION H8-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015256.3|UniProtKB=G3RMY3 G3RMY3 AVPI1 PTHR14350:SF2 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056 GORGO|Ensembl=ENSGGOG00000043708.1|UniProtKB=A0A2I2ZMF4 A0A2I2ZMF4 PTHR10655:SF58 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;catalytic activity, acting on a protein#GO:0140096;carboxylic ester hydrolase activity#GO:0052689;thiolester hydrolase activity#GO:0016790;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;regulation of vesicle-mediated transport#GO:0060627;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 lipase#PC00143;phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000037849.1|UniProtKB=A0A2I2Z9T6 A0A2I2Z9T6 PTHR12277:SF52 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17A catalytic activity, acting on a protein#GO:0140096;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of synapse structure or activity#GO:0050803;regulation of synapse organization#GO:0050807 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000007704.3|UniProtKB=G3QXJ5 G3QXJ5 GNL2 PTHR11089:SF9 GTP-BINDING PROTEIN-RELATED NUCLEOLAR GTP-BINDING PROTEIN 2 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000003799.3|UniProtKB=A0A2I2ZJ66 A0A2I2ZJ66 ERP29 PTHR12211:SF1 ENDOPLASMIC RETICULUM PROTEIN ERP29 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 29 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 gene expression#GO:0010467;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;protein folding#GO:0006457;regulation of cell communication#GO:0010646;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of intrinsic apoptotic signaling pathway#GO:2001242;protein metabolic process#GO:0019538;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000003697.3|UniProtKB=G3QM99 G3QM99 PCLAF PTHR15679:SF8 PCNA-ASSOCIATED FACTOR PCNA-ASSOCIATED FACTOR DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000038516.1|UniProtKB=A0A2I2ZLL1 A0A2I2ZLL1 RPS24 PTHR10496:SF7 40S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN ES24 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006028.3|UniProtKB=G3QT84 G3QT84 TYK2 PTHR45807:SF6 TYROSINE-PROTEIN KINASE HOPSCOTCH NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;cytokine receptor binding#GO:0005126;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to peptide hormone stimulus#GO:0071375;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;immune response#GO:0006955;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to other organism#GO:0051707;response to peptide hormone#GO:0043434;developmental process#GO:0032502;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;cellular developmental process#GO:0048869;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;cellular response to hormone stimulus#GO:0032870;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;type I interferon-mediated signaling pathway#GO:0060337;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;response to stress#GO:0006950;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;response to type II interferon#GO:0034341;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;defense response to other organism#GO:0098542;cell surface receptor signaling pathway via STAT#GO:0097696;cell surface receptor signaling pathway#GO:0007166 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>JAK#P00846 GORGO|Ensembl=ENSGGOG00000012211.3|UniProtKB=G3R934 G3R934 PPP1R14B PTHR16188:SF20 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;protein serine/threonine phosphatase inhibitor activity#GO:0004865;phosphatase regulator activity#GO:0019208;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000015734.3|UniProtKB=A0A2I2YF02 A0A2I2YF02 TBC1D4 PTHR22957:SF195 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 4 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 transport#GO:0006810;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytosol#GO:0005829 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000013820.3|UniProtKB=G3RD88 G3RD88 TMEM87B PTHR21229:SF16 LUNG SEVEN TRANSMEMBRANE RECEPTOR TRANSMEMBRANE PROTEIN 87B endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000038124.1|UniProtKB=A0A2I2ZJR0 A0A2I2ZJR0 C21H20orf144 PTHR37335:SF1 RIKEN CDNA 1700003F12 GENE RIKEN CDNA 1700003F12 GENE GORGO|Ensembl=ENSGGOG00000036765.1|UniProtKB=G3RDL4 G3RDL4 LOC101137272 PTHR24257:SF19 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2B serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;catabolic process#GO:0009056;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;proteolysis#GO:0006508;regulation of platelet activation#GO:0010543;regulation of platelet aggregation#GO:0090330;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cellular process#GO:0009987;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000027396.2|UniProtKB=G3SD88 G3SD88 CHORDC1 PTHR46983:SF4 CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000041409.1|UniProtKB=A0A2I2ZPF7 A0A2I2ZPF7 PTHR15896:SF11 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000027513.2|UniProtKB=G3S7B2 G3S7B2 TAS2R7 PTHR11394:SF58 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 7 signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003518.3|UniProtKB=A0A2I2ZNA8 A0A2I2ZNA8 NCSTN PTHR21092:SF1 NICASTRIN NICASTRIN gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 Alzheimer disease-presenilin pathway#P00004>Nicastrin#P00115;Notch signaling pathway#P00045>Nicastrin#P01108;Alzheimer disease-amyloid secretase pathway#P00003>Nicastrin#P00095 GORGO|Ensembl=ENSGGOG00000009378.3|UniProtKB=G3R1T7 G3R1T7 TBL3 PTHR19854:SF15 TRANSDUCIN BETA-LIKE 3 TRANSDUCIN BETA-LIKE PROTEIN 3 U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000042199.1|UniProtKB=A0A2I2YS20 A0A2I2YS20 PTHR11183:SF164 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN-1 transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;glucosyltransferase activity#GO:0046527 polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112;glucan biosynthetic process#GO:0009250;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;generation of precursor metabolites and energy#GO:0006091;glycogen biosynthetic process#GO:0005978;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000007840.3|UniProtKB=A0A2I2ZR76 A0A2I2ZR76 CLN6 PTHR16244:SF2 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 6 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 6 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;organelle lumen#GO:0043233;membrane raft#GO:0045121;intracellular vesicle#GO:0097708;membrane microdomain#GO:0098857;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;endoplasmic reticulum lumen#GO:0005788 GORGO|Ensembl=ENSGGOG00000017007.3|UniProtKB=G3RLF4 G3RLF4 TNMD PTHR14064:SF3 CHONDROMODULIN-RELATED TENOMODULIN regulation of vasculature development#GO:1901342;negative regulation of cellular process#GO:0048523;regulation of angiogenesis#GO:0045765;negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cell population proliferation#GO:0042127;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of cell population proliferation#GO:0008285;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794 GORGO|Ensembl=ENSGGOG00000001591.3|UniProtKB=A0A2I2Z1Q1 A0A2I2Z1Q1 RASA1 PTHR10194:SF146 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 1 GTPase-activating protein#PC00257 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Ras#P00886;EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646;Interleukin signaling pathway#P00036>RasGAP#P00975;Angiogenesis#P00005>GAP#P00205;Angiogenesis#P00005>RasGAP#P00190 GORGO|Ensembl=ENSGGOG00000002769.3|UniProtKB=G3QJX0 G3QJX0 TRAM1 PTHR12371:SF3 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 1 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 GORGO|Ensembl=ENSGGOG00000013463.3|UniProtKB=G3RCB0 G3RCB0 RSL1D1 PTHR23105:SF31 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000002680.3|UniProtKB=G3QJP1 G3QJP1 MDFI PTHR15304:SF1 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of JNK cascade#GO:0046328;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000005789.3|UniProtKB=G3S7R2 G3S7R2 PRR22 PTHR37871:SF1 PROLINE-RICH PROTEIN 22 PROLINE-RICH PROTEIN 22 GORGO|Ensembl=ENSGGOG00000004989.3|UniProtKB=G3QQL8 G3QQL8 MGST2 PTHR10250:SF13 MICROSOMAL GLUTATHIONE S-TRANSFERASE MICROSOMAL GLUTATHIONE S-TRANSFERASE 2 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity#GO:0016491;glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 organelle envelope#GO:0031967;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000025953.2|UniProtKB=G3RZ75 G3RZ75 RBL2 PTHR13742:SF8 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-LIKE PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;cellular developmental process#GO:0048869 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000006169.3|UniProtKB=A0A2I2YIR7 A0A2I2YIR7 PDCD5 PTHR10840:SF2 PROGRAMMED CELL DEATH PROTEIN 5 PROGRAMMED CELL DEATH PROTEIN 5 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000005318.3|UniProtKB=G3QRF8 G3QRF8 TXNRD3 PTHR48105:SF30 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN REDUCTASE 3 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000042596.1|UniProtKB=A0A2I2ZA33 A0A2I2ZA33 PTHR12595:SF18 POS9-ACTIVATING FACTOR FAP7-RELATED AK6 nucleotide binding#GO:0000166;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;carbohydrate derivative binding#GO:0097367;phosphotransferase activity, phosphate group as acceptor#GO:0016776;binding#GO:0005488;ATP binding#GO:0005524;nucleobase-containing compound kinase activity#GO:0019205;nucleoside phosphate binding#GO:1901265 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000042719.1|UniProtKB=A0A2I2ZDV5 A0A2I2ZDV5 ATXN1L PTHR13392:SF6 ATAXIN 1 ATAXIN-1-LIKE RNA binding#GO:0003723;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of macromolecule biosynthetic process#GO:0010558;head development#GO:0060322;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003237.3|UniProtKB=G3QL39 G3QL39 ANKK1 PTHR24198:SF175 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000003398.3|UniProtKB=G3QLI5 G3QLI5 ZNF296 PTHR45993:SF2 B-CELL LYMPHOMA/LEUKEMIA 11 ZINC FINGER PROTEIN 296 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of neuron projection development#GO:0010975;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;regulation of developmental process#GO:0050793;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000039521.1|UniProtKB=A0A2I2ZQD0 A0A2I2ZQD0 LOC101141782 PTHR31866:SF1 GENE 4779-RELATED GENE 4779-RELATED GORGO|Ensembl=ENSGGOG00000025305.2|UniProtKB=G3RSW3 G3RSW3 DMAC1 PTHR36469:SF1 DISTAL MEMBRANE-ARM ASSEMBLY COMPLEX PROTEIN 1 DISTAL MEMBRANE-ARM ASSEMBLY COMPLEX PROTEIN 1 cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009599.3|UniProtKB=G3R2C7 G3R2C7 DTWD2 PTHR21392:SF0 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 GORGO|Ensembl=ENSGGOG00000005819.3|UniProtKB=A0A2I2Y591 A0A2I2Y591 PTHR12146:SF10 40S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN ES10 RNA binding#GO:0003723;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008159.3|UniProtKB=G3QYN4 G3QYN4 LOC101143890 PTHR26453:SF622 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008538.3|UniProtKB=G3QZM8 G3QZM8 ZNF614 PTHR24377:SF849 IP01015P-RELATED ZINC FINGER PROTEIN 614 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015875.3|UniProtKB=G3S4C4 G3S4C4 TATDN1 PTHR10060:SF15 TATD FAMILY DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE TATDN1 exonuclease activity#GO:0004527;hydrolase activity#GO:0016787;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000005972.3|UniProtKB=G3RRG6 G3RRG6 APC PTHR12607:SF11 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY ADENOMATOUS POLYPOSIS COLI PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 negative regulation of response to stimulus#GO:0048585;cell migration#GO:0016477;negative regulation of Wnt signaling pathway#GO:0030178;multicellular organismal process#GO:0032501;negative regulation of protein depolymerization#GO:1901880;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cell communication#GO:0010646;regulation of microtubule-based process#GO:0032886;pattern specification process#GO:0007389;negative regulation of protein-containing complex disassembly#GO:0043242;anatomical structure development#GO:0048856;negative regulation of cytoskeleton organization#GO:0051494;system development#GO:0048731;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;cell fate specification#GO:0001708;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of Wnt signaling pathway#GO:0030111;animal gross anatomical part developmental process#GO:0160108;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;cell fate commitment#GO:0045165 cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;intracellular protein-containing complex#GO:0140535;extrinsic component of membrane#GO:0019898;membraneless organelle#GO:0043228;extrinsic component of plasma membrane#GO:0019897;polymeric cytoskeletal fiber#GO:0099513;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874 Wnt signaling pathway#P00057>APC#P01468;Angiogenesis#P00005>APC#P00195 GORGO|Ensembl=ENSGGOG00000041375.1|UniProtKB=A0A2I2YEE3 A0A2I2YEE3 PTHR19879:SF6 TRANSCRIPTION INITIATION FACTOR TFIID TAF5-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 5L protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 nucleic acid biosynthetic process#GO:0141187;regulation of RNA metabolic process#GO:0051252;RNA metabolic process#GO:0016070;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription initiation#GO:0006352;regulation of cellular process#GO:0050794;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;transcription initiation at RNA polymerase II promoter#GO:0006367;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;gene expression#GO:0010467 organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;acetyltransferase complex#GO:1902493;SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;peptidase complex#GO:1905368;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667 GORGO|Ensembl=ENSGGOG00000025619.2|UniProtKB=G3SJZ0 G3SJZ0 FAAH2 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000028135.2|UniProtKB=G3S8F4 G3S8F4 VIP PTHR11213:SF5 GLUCAGON-FAMILY NEUROPEPTIDE VIP PEPTIDES signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;neuropeptide hormone activity#GO:0005184;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;hormone receptor binding#GO:0051427;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of protein localization#GO:0032880;secretion by cell#GO:0032940;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;secretion#GO:0046903;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;export from cell#GO:0140352;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;transport#GO:0006810;regulation of response to stimulus#GO:0048583;regulation of localization#GO:0032879;establishment of localization#GO:0051234;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 neuropeptide#PC00162 GORGO|Ensembl=ENSGGOG00000006609.3|UniProtKB=G3QUR8 G3QUR8 PPP6R3 PTHR12634:SF12 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 3 protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000043201.1|UniProtKB=A0A2I2YQ39 A0A2I2YQ39 KRTAP22-1 PTHR39653:SF2 KERATIN-ASSOCIATED PROTEIN 20-2 KERATIN-ASSOCIATED PROTEIN 22-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000012394.3|UniProtKB=G3R9K3 G3R9K3 PTHR12570:SF17 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MAGNESIUM TRANSPORTER NIPA1 establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;magnesium ion transport#GO:0015693;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000016990.3|UniProtKB=G3RLE0 G3RLE0 SERPINA4 PTHR11461:SF194 SERINE PROTEASE INHIBITOR, SERPIN KALLISTATIN endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000038266.1|UniProtKB=A0A2I2YJF2 A0A2I2YJF2 SLC39A1 PTHR11040:SF58 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000014101.3|UniProtKB=G3RDZ5 G3RDZ5 COX6A1 PTHR11504:SF11 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT 6A1, MITOCHONDRIAL enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000037697.1|UniProtKB=A0A2I2ZDI0 A0A2I2ZDI0 LOC101132985 PTHR26453:SF650 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000028472.2|UniProtKB=G3RNT5 G3RNT5 PTHR12221:SF7 PESCADILLO - RELATED PESCADILLO HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843 ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;90S preribosome#GO:0030686;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001993.3|UniProtKB=G3QHX6 G3QHX6 LOC101151331 PTHR16675:SF289 MHC CLASS I-RELATED ZINC-ALPHA-2-GLYCOPROTEIN regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000008490.3|UniProtKB=G3QZK2 G3QZK2 CFAP54 PTHR33487:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 54 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 54 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000026798.2|UniProtKB=A0A2I2ZUL3 A0A2I2ZUL3 WDR41 PTHR22805:SF2 WDR41-RELATED WD REPEAT-CONTAINING PROTEIN 41 GORGO|Ensembl=ENSGGOG00000010037.3|UniProtKB=G3R3H5 G3R3H5 DHX34 PTHR18934:SF278 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX34-RELATED RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008508.3|UniProtKB=G3QZK5 G3QZK5 SNTA1 PTHR10554:SF6 SYNTROPHIN ALPHA-1-SYNTROPHIN transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;heart process#GO:0003015;muscle system process#GO:0003012;action potential#GO:0001508;striated muscle contraction#GO:0006941;actin-mediated cell contraction#GO:0070252;muscle contraction#GO:0006936;system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle cell contraction#GO:0086003;regulation of membrane potential#GO:0042391;actin filament-based movement#GO:0030048;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cardiac muscle cell action potential involved in contraction#GO:0086002;blood circulation#GO:0008015 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;sarcolemma#GO:0042383;neuromuscular junction#GO:0031594 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004506.3|UniProtKB=A0A2I2YK76 A0A2I2YK76 CCDC7 PTHR22035:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 7 COILED-COIL DOMAIN-CONTAINING PROTEIN 7 GORGO|Ensembl=ENSGGOG00000006183.3|UniProtKB=G3RYI4 G3RYI4 PTHR24343:SF120 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cell differentiation#GO:0030154;gamete generation#GO:0007276;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;male gamete generation#GO:0048232;cellular process#GO:0009987;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000022841.2|UniProtKB=G3SIS9 G3SIS9 PTHR43908:SF4 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY B MEMBER 14 protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;heat shock protein binding#GO:0031072 primary metabolic process#GO:0044238;response to misfolded protein#GO:0051788;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular response to misfolded protein#GO:0071218;macromolecule metabolic process#GO:0043170 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000004584.3|UniProtKB=G3QPK3 G3QPK3 PABPC1L PTHR24012:SF933 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1-LIKE single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488 sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;gamete generation#GO:0007276;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;cell maturation#GO:0048469;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;developmental maturation#GO:0021700;biological regulation#GO:0065007;oogenesis#GO:0048477 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;cytosol#GO:0005829;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010477.3|UniProtKB=G3R4N3 G3R4N3 WDR17 PTHR44464:SF1 WD REPEAT-CONTAINING PROTEIN 17 WD REPEAT-CONTAINING PROTEIN 17 GORGO|Ensembl=ENSGGOG00000041622.1|UniProtKB=A0A2I2YAB5 A0A2I2YAB5 LTB4R2 PTHR24230:SF8 G-PROTEIN COUPLED RECEPTOR LEUKOTRIENE B4 RECEPTOR 2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000039837.1|UniProtKB=A0A2I2YC14 A0A2I2YC14 PTHR11599:SF244 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-1 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 proteasome complex#GO:0000502;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000013822.3|UniProtKB=G3RD86 G3RD86 P2RX7 PTHR10125:SF13 P2X PURINOCEPTOR P2X PURINOCEPTOR 7 gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 calcium ion transport#GO:0006816;establishment of localization#GO:0051234;transport#GO:0006810;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;signal transduction#GO:0007165;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;signaling#GO:0023052;metal ion transport#GO:0030001;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;calcium ion transmembrane transport#GO:0070588 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000038728.1|UniProtKB=A0A2I2YJY9 A0A2I2YJY9 IFFO2 PTHR14516:SF1 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER INTERMEDIATE FILAMENT FAMILY ORPHAN 2 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000011178.3|UniProtKB=G3R6E5 G3R6E5 NAIF1 PTHR23098:SF7 AGAP001331-PA-RELATED NUCLEAR APOPTOSIS-INDUCING FACTOR 1 GORGO|Ensembl=ENSGGOG00000022973.2|UniProtKB=A0A2I2YZ45 A0A2I2YZ45 LOC101133154 PTHR11346:SF170 GALECTIN GALECTIN-9 carbohydrate binding#GO:0030246;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of metabolic process#GO:0009892;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of biological process#GO:0048518;negative regulation of cell-cell adhesion#GO:0022408;positive regulation of macromolecule metabolic process#GO:0010604;regulation of T cell activation#GO:0050863;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;negative regulation of multicellular organismal process#GO:0051241;regulation of macromolecule metabolic process#GO:0060255;regulation of T cell proliferation#GO:0042129;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;negative regulation of cell activation#GO:0050866;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of cytokine production#GO:0001817;negative regulation of cell population proliferation#GO:0008285;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;negative regulation of cell adhesion#GO:0007162;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;negative regulation of biosynthetic process#GO:0009890;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000005190.3|UniProtKB=G3QR50 G3QR50 BRINP1 PTHR15564:SF7 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 1 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;negative regulation of mitotic cell cycle#GO:0045930;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;generation of neurons#GO:0048699;response to oxygen-containing compound#GO:1901700;cell differentiation#GO:0030154;central nervous system development#GO:0007417;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell body#GO:0044297 GORGO|Ensembl=ENSGGOG00000015064.3|UniProtKB=A0A2I2Z2K7 A0A2I2Z2K7 CENPE PTHR47968:SF83 CENTROMERE PROTEIN E CENTROMERE-ASSOCIATED PROTEIN E binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;cell cycle#GO:0007049;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 GORGO|Ensembl=ENSGGOG00000001484.3|UniProtKB=G3RMB2 G3RMB2 RNPEPL1 PTHR45726:SF2 LEUKOTRIENE A-4 HYDROLASE AMINOPEPTIDASE RNPEPL1 hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 GORGO|Ensembl=ENSGGOG00000025633.2|UniProtKB=G3RVD3 G3RVD3 SCRG1 PTHR17463:SF0 SCRAPIE-RESPONSIVE PROTEIN 1 SCRG1 SCRAPIE-RESPONSIVE PROTEIN 1 neuron projection#GO:0043005;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuron projection terminus#GO:0044306;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000012899.3|UniProtKB=G3SCK9 G3SCK9 LTBP2 PTHR24034:SF49 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 2 binding#GO:0005488;extracellular matrix binding#GO:0050840 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000041364.1|UniProtKB=A0A2I2ZDW6 A0A2I2ZDW6 PTHR19343:SF0 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 23_DELTA VARIABLE 6 binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000006015.3|UniProtKB=G3QT77 G3QT77 RAVER1 PTHR23189:SF46 RNA RECOGNITION MOTIF-CONTAINING RIBONUCLEOPROTEIN PTB-BINDING 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007202.3|UniProtKB=G3QW99 G3QW99 SPINT1 PTHR46750:SF1 KUNITZ-TYPE PROTEASE INHIBITOR 1 KUNITZ-TYPE PROTEASE INHIBITOR 1 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000028149.2|UniProtKB=A0A2I2Z8R4 A0A2I2Z8R4 PTHR12653:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;electron transport chain#GO:0022900;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000013592.3|UniProtKB=G3RCN0 G3RCN0 BCKDK PTHR11947:SF20 PYRUVATE DEHYDROGENASE KINASE BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009307.3|UniProtKB=G3R1L3 G3R1L3 GLI4 PTHR23226:SF197 ZINC FINGER AND SCAN DOMAIN-CONTAINING GLI FAMILY ZINC FINGER 4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015057.3|UniProtKB=G3S2C7 G3S2C7 PLIN3 PTHR14024:SF11 PERILIPIN PERILIPIN-3 regulation of localization#GO:0032879;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;lipid storage#GO:0019915;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004299.3|UniProtKB=G3QNU2 G3QNU2 SUCNR1 PTHR24231:SF14 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR SUCCINATE RECEPTOR 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000014321.3|UniProtKB=G3REH9 G3REH9 PTHR46404:SF1 DNA POLYMERASE IOTA DNA POLYMERASE IOTA DNA-directed DNA polymerase activity#GO:0003887;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097 DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000016745.3|UniProtKB=A0A2I2Y9G6 A0A2I2Y9G6 NEK8 PTHR44535:SF4 PROTEIN CBG16200 SERINE_THREONINE-PROTEIN KINASE NEK8 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;determination of left/right symmetry#GO:0007368;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;determination of bilateral symmetry#GO:0009855;heart development#GO:0007507;multicellular organismal process#GO:0032501;regionalization#GO:0003002;multicellular organism development#GO:0007275;animal organ development#GO:0048513;left/right pattern formation#GO:0060972;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;specification of symmetry#GO:0009799 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000026797.2|UniProtKB=A0A2I2YYJ7 A0A2I2YYJ7 PTHR19431:SF5 60S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4 structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004280.3|UniProtKB=G3QNS6 G3QNS6 PRSS55 PTHR24253:SF90 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 55 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000005127.3|UniProtKB=G3RPY1 G3RPY1 BLK PTHR24418:SF181 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BLK binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;B cell activation#P00010>Blk#P00390 GORGO|Ensembl=ENSGGOG00000007235.3|UniProtKB=G3QWD0 G3QWD0 PREPL PTHR11757:SF23 PROTEASE FAMILY S9A OLIGOPEPTIDASE PROLYL ENDOPEPTIDASE-LIKE Golgi vesicle transport#GO:0048193;transport#GO:0006810;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;vesicle-mediated transport#GO:0016192;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cytosolic transport#GO:0016482;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 serine protease#PC00203 Vasopressin synthesis#P04395>Endo Peptidase#P04596 GORGO|Ensembl=ENSGGOG00000037412.1|UniProtKB=A0A2I2YRE8 A0A2I2YRE8 ERBB3 PTHR24416:SF88 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3 transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;epidermal growth factor receptor signaling pathway#GO:0007173;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;membrane#GO:0016020;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466 GORGO|Ensembl=ENSGGOG00000001768.3|UniProtKB=A0A2I2ZCS0 A0A2I2ZCS0 PTHR23226:SF238 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 528 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008978.3|UniProtKB=G3R0T7 G3R0T7 ADGRD2 PTHR12011:SF58 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR D2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000011607.3|UniProtKB=G3R7I3 G3R7I3 RPS6KL1 PTHR15508:SF4 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE-LIKE 1 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142 GORGO|Ensembl=ENSGGOG00000004638.3|UniProtKB=G3QPP5 G3QPP5 DNTTIP1 PTHR23399:SF2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000011045.3|UniProtKB=A0A2I2Y1W4 A0A2I2Y1W4 EFR3B PTHR12444:SF4 PROTEIN EFR3 HOMOLOG CMP44E PROTEIN EFR3 HOMOLOG B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000009561.3|UniProtKB=G3R2C3 G3R2C3 PTHR10574:SF274 NETRIN/LAMININ-RELATED USHERIN anatomical structure development#GO:0048856;tissue development#GO:0009888;developmental process#GO:0032502 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000038448.1|UniProtKB=A0A2I2Y419 A0A2I2Y419 TIMM22 PTHR14110:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular transport#GO:0046907;transport#GO:0006810;mitochondrion organization#GO:0007005;protein insertion into mitochondrial inner membrane#GO:0045039;membrane organization#GO:0061024;mitochondrial protein import pathway#GO:7770058;organelle organization#GO:0006996;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization#GO:0016043 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000026386.2|UniProtKB=A0A2I2Z0R3 A0A2I2Z0R3 LOC101128766 PTHR48018:SF49 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010286.3|UniProtKB=G3RWX6 G3RWX6 IGF2BP3 PTHR10288:SF158 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 3 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;system development#GO:0048731;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000024451.2|UniProtKB=G3S0E1 G3S0E1 CH25H PTHR11863:SF213 STEROL DESATURASE CHOLESTEROL 25-HYDROXYLASE catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000028609.2|UniProtKB=G3SBX3 G3SBX3 PTHR23267:SF375 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-27 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010408.3|UniProtKB=G3R4F7 G3R4F7 SHC4 PTHR10337:SF12 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022817.2|UniProtKB=G3SGT2 G3SGT2 ZNF217 PTHR45925:SF4 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 217 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003511.3|UniProtKB=G3QLT4 G3QLT4 TRNAU1AP PTHR37457:SF2 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1 RNA binding#GO:0003723;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488 protein metabolic process#GO:0019538;translation#GO:0006412;regulation of macromolecule metabolic process#GO:0060255;protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;translational elongation#GO:0006414;metabolic process#GO:0008152;post-transcriptional regulation of gene expression#GO:0010608;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000010483.3|UniProtKB=G3R4L6 G3R4L6 CD40LG PTHR11471:SF5 TUMOR NECROSIS FACTOR FAMILY MEMBER CD40 LIGAND cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of apoptotic signaling pathway#GO:2001233 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000027142.2|UniProtKB=G3SGY1 G3SGY1 PTHR23003:SF65 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE_ARGININE-RICH SPLICING FACTOR 9 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000009070.3|UniProtKB=G3RTS6 G3RTS6 BCL7B PTHR12767:SF5 BCL7 RELATED B-CELL CLL_LYMPHOMA 7 PROTEIN FAMILY MEMBER B signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 ATPase complex#GO:1904949;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000006243.3|UniProtKB=G3RRP8 G3RRP8 PTHR23402:SF15 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED PYROGLUTAMYL-PEPTIDASE 1-LIKE PROTEIN catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000036188.1|UniProtKB=A0A2I2YIQ5 A0A2I2YIQ5 PTHR11426:SF247 HISTONE H3 HISTONE H3.3C-LIKE cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 GORGO|Ensembl=ENSGGOG00000025516.2|UniProtKB=G3RYR1 G3RYR1 PTHR23105:SF206 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER 60S RIBOSOMAL PROTEIN L7A binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000016690.3|UniProtKB=G3RKL3 G3RKL3 PTHR16675:SF232 MHC CLASS I-RELATED UL-16 BINDING PROTEIN 5 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;response to other organism#GO:0051707;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;positive regulation of leukocyte mediated immunity#GO:0002705;cell killing#GO:0001906;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;leukocyte mediated cytotoxicity#GO:0001909;regulation of biological process#GO:0050789;natural killer cell mediated immunity#GO:0002228;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cell killing#GO:0031341;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;cellular process#GO:0009987;natural killer cell mediated cytotoxicity#GO:0042267;immune effector process#GO:0002252 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000000908.3|UniProtKB=G3QF32 G3QF32 SLC35A3 PTHR23504:SF77 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 71 MEMBER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 system process#GO:0003008;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;gamete generation#GO:0007276;multicellular organismal process#GO:0032501;male gamete generation#GO:0048232;developmental process involved in reproduction#GO:0003006 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006580.3|UniProtKB=G3RR21 G3RR21 AP3D1 PTHR22781:SF14 DELTA ADAPTIN-RELATED AP-3 COMPLEX SUBUNIT DELTA-1 axo-dendritic transport#GO:0008088;synaptic vesicle membrane organization#GO:0048499;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;synaptic vesicle recycling#GO:0036465;cytoskeleton-dependent intracellular transport#GO:0030705;membrane organization#GO:0061024;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;establishment of protein localization to organelle#GO:0072594;vesicle budding from membrane#GO:0006900;anterograde synaptic vesicle transport#GO:0048490;vesicle cytoskeletal trafficking#GO:0099518;intracellular protein localization#GO:0008104;microtubule-based movement#GO:0007018;protein localization to organelle#GO:0033365;organelle localization#GO:0051640;protein localization to vacuole#GO:0072665;axonal transport#GO:0098930;endosome to lysosome transport#GO:0008333;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;anterograde axonal transport#GO:0008089;protein targeting to vacuole#GO:0006623;synaptic vesicle transport#GO:0048489;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;endomembrane system organization#GO:0010256;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;vesicle organization#GO:0016050;endosomal transport#GO:0016197;cellular component organization#GO:0016043;protein localization to lysosome#GO:0061462;establishment of organelle localization#GO:0051656;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;lysosomal transport#GO:0007041;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892 coated membrane#GO:0048475;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular vesicle#GO:0097708;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;neuron projection#GO:0043005;presynapse#GO:0098793;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117;axon#GO:0030424;neuron projection terminus#GO:0044306;intracellular membrane-bounded organelle#GO:0043231;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;vesicle#GO:0031982;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;axon terminus#GO:0043679;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013206.3|UniProtKB=G3RBM2 G3RBM2 LDLRAD2 PTHR24652:SF67 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000039041.1|UniProtKB=A0A2I2YPB3 A0A2I2YPB3 ERVMER34-1 PTHR10424:SF78 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRAL ENVELOPE PROTEIN HEMO developmental process#GO:0032502;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;striated muscle cell differentiation#GO:0051146;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;myoblast fusion#GO:0007520;cell differentiation#GO:0030154;muscle structure development#GO:0061061 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000016242.3|UniProtKB=A0A2I2Z666 A0A2I2Z666 PTHR10218:SF328 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-11 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of membrane potential#GO:0042391;action potential#GO:0001508;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;regulation of biological quality#GO:0065008 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 Wnt signaling pathway#P00057>Galpha#P01451;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Gonadotropin-releasing hormone receptor pathway#P06664>gnaq/11#P06841;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Endothelin signaling pathway#P00019>Gq#P00586;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Alpha adrenergic receptor signaling pathway#P00002>G-Protein#P00077 GORGO|Ensembl=ENSGGOG00000000804.3|UniProtKB=A0A2I2ZQR7 A0A2I2ZQR7 PTHR22529:SF1 EPITHELIAL-STROMAL INTERACTION PROTEIN 1 EPITHELIAL-STROMAL INTERACTION PROTEIN 1 immune system process#GO:0002376;cell activation#GO:0001775;inflammatory response#GO:0006954;macrophage activation#GO:0042116;defense response#GO:0006952;response to stress#GO:0006950;leukocyte activation#GO:0045321;cellular process#GO:0009987;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;myeloid leukocyte activation#GO:0002274 GORGO|Ensembl=ENSGGOG00000013356.3|UniProtKB=G3RC08 G3RC08 TOR1A PTHR10760:SF15 TORSIN TORSIN-1A protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 protein localization to organelle#GO:0033365;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein localization to nucleus#GO:0034504;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;nucleus organization#GO:0006997;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nuclear envelope organization#GO:0006998;intracellular protein localization#GO:0008104 organelle envelope#GO:0031967;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 GORGO|Ensembl=ENSGGOG00000001127.3|UniProtKB=G3QFN4 G3QFN4 SNRPF PTHR11021:SF9 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F SMALL NUCLEAR RIBONUCLEOPROTEIN F RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000014735.3|UniProtKB=G3S7D1 G3S7D1 PIK3CG PTHR10048:SF34 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 phosphatidylinositol phosphate biosynthetic process#GO:0046854;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid biosynthetic process#GO:0008654;cell motility#GO:0048870;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886 kinase#PC00137 p53 pathway feedback loops 2#P04398>PI3K#P04661;Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;Ras Pathway#P04393>PI3K#P04567;Apoptosis signaling pathway#P00006>PI3K#P00310;PDGF signaling pathway#P00047>PI3K#P01168;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;B cell activation#P00010>PI3K#P00391;FGF signaling pathway#P00021>PI3K#P00640;T cell activation#P00053>PI3K#P01322;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;VEGF signaling pathway#P00056>PI3K#P01413;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557 GORGO|Ensembl=ENSGGOG00000011006.3|UniProtKB=A0A2I2Z305 A0A2I2Z305 DROSHA PTHR11207:SF37 RIBONUCLEASE III RIBONUCLEASE 3 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;RNA biosynthetic process#GO:0032774;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;primary miRNA processing#GO:0031053;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629 endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000007163.3|UniProtKB=G3QW59 G3QW59 PTHR20852:SF90 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000037645.1|UniProtKB=A0A2I2YU64 A0A2I2YU64 ACTR1B PTHR11937:SF195 ACTIN BETA-CENTRACTIN cytoskeletal adaptor activity#GO:0008093;structural constituent of cytoskeleton#GO:0005200;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495;structural molecule activity#GO:0005198 nuclear migration#GO:0007097;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 GORGO|Ensembl=ENSGGOG00000003708.3|UniProtKB=G3SJ72 G3SJ72 MBTD1 PTHR12247:SF79 POLYCOMB GROUP PROTEIN MBT DOMAIN-CONTAINING PROTEIN 1 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004030.3|UniProtKB=G3QN60 G3QN60 DNAH6 PTHR46532:SF11 MALE FERTILITY FACTOR KL5 DYNEIN AXONEMAL HEAVY CHAIN 12 GORGO|Ensembl=ENSGGOG00000037291.1|UniProtKB=A0A2I2Z6P8 A0A2I2Z6P8 SPEM3 PTHR34834:SF3 SPERMATID MATURATION PROTEIN 1 SPEM FAMILY MEMBER 3 anatomical structure formation involved in morphogenesis#GO:0048646;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;multicellular organismal process#GO:0032501;male gamete generation#GO:0048232;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285;spermatid development#GO:0007286;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell differentiation#GO:0030154;germ cell development#GO:0007281;sperm motility#GO:0097722;anatomical structure morphogenesis#GO:0009653;developmental process involved in reproduction#GO:0003006 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000007552.3|UniProtKB=A0A2I2YE97 A0A2I2YE97 VWA5B2 PTHR46299:SF2 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2-RELATED VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2 GORGO|Ensembl=ENSGGOG00000002130.3|UniProtKB=G3QI94 G3QI94 CCDC169 PTHR16223:SF415 TRANSCRIPTION FACTOR BHLH83-RELATED SPERMATOGENESIS- AND OOGENESIS-SPECIFIC BASIC HELIX-LOOP-HELIX-CONTAINING PROTEIN 2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000005514.3|UniProtKB=A0A2I2ZB70 A0A2I2ZB70 MPDZ PTHR19964:SF10 MULTIPLE PDZ DOMAIN PROTEIN MULTIPLE PDZ DOMAIN PROTEIN cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical part of cell#GO:0045177;apical junction complex#GO:0043296;plasma membrane#GO:0005886;cytoplasm#GO:0005737;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003711.3|UniProtKB=G3QMB1 G3QMB1 FETUB PTHR13814:SF10 FETUIN FETUIN-B endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988;sperm-egg recognition#GO:0035036;sexual reproduction#GO:0019953;cell recognition#GO:0008037;reproductive process#GO:0022414;fertilization#GO:0009566;single fertilization#GO:0007338;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000025821.2|UniProtKB=G3SCL6 G3SCL6 PIAS2 PTHR10782:SF12 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS2 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;acyltransferase activity#GO:0016746;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678 protein sumoylation#GO:0016925;metabolic process#GO:0008152;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;regulation of signaling#GO:0023051;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;primary metabolic process#GO:0044238;protein modification process#GO:0036211 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958;JAK/STAT signaling pathway#P00038>PIAS#P01031 GORGO|Ensembl=ENSGGOG00000041121.1|UniProtKB=A0A2I2ZIM6 A0A2I2ZIM6 PTHR12400:SF81 INOSITOL POLYPHOSPHATE KINASE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000026170.2|UniProtKB=G3SK27 G3SK27 CKAP2L PTHR47078:SF1 CYTOSKELETON-ASSOCIATED PROTEIN 2-LIKE CYTOSKELETON-ASSOCIATED PROTEIN 2-LIKE intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000012084.3|UniProtKB=G3R8S2 G3R8S2 MKNK1 PTHR24349:SF114 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-INTERACTING SERINE_THREONINE-PROTEIN KINASE 1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MNK1/2#P01137;Interleukin signaling pathway#P00036>MNK1/2#P00972;PDGF signaling pathway#P00047>MNK1/2#P01149;p38 MAPK pathway#P05918>MNK1#P06018 GORGO|Ensembl=ENSGGOG00000022255.2|UniProtKB=G3RW00 G3RW00 AUNIP PTHR14526:SF2 AURORA KINASE A AND NINEIN-INTERACTING PROTEIN AURORA KINASE A- AND NINEIN-INTERACTING PROTEIN molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;cell cycle#GO:0007049;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;microtubule-based process#GO:0007017;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007954.3|UniProtKB=A0A2I2YDK7 A0A2I2YDK7 GGNBP2 PTHR13601:SF3 GAMETOGENETIN-BINDING PROTEIN 2 GAMETOGENETIN-BINDING PROTEIN 2 negative regulation of signaling#GO:0023057;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;regulation of signaling#GO:0023051;anatomical structure development#GO:0048856;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;placenta development#GO:0001890;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;embryo development#GO:0009790;negative regulation of signal transduction#GO:0009968 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004819.3|UniProtKB=G3QQ61 G3QQ61 RXFP3 PTHR24230:SF70 G-PROTEIN COUPLED RECEPTOR RELAXIN-3 RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000038485.1|UniProtKB=A0A2I2YKY5 A0A2I2YKY5 DNAJB8 PTHR43948:SF9 DNAJ HOMOLOG SUBFAMILY B DNAJ HOMOLOG SUBFAMILY B MEMBER 8 protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000009556.3|UniProtKB=G3SJ47 G3SJ47 FAM98A PTHR31353:SF9 FAM98 PROTEIN FAM98A intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000027759.2|UniProtKB=G3S5T6 G3S5T6 ERICH2 PTHR21520:SF2 GLUTAMATE-RICH PROTEIN 2 GLUTAMATE-RICH PROTEIN 2 GORGO|Ensembl=ENSGGOG00000002838.4|UniProtKB=A0A2I2YY48 A0A2I2YY48 GALK2 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137;carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Galactokinase#P02960 GORGO|Ensembl=ENSGGOG00000014308.3|UniProtKB=G3RMI6 G3RMI6 MYBL2 PTHR45614:SF30 MYB PROTEIN-RELATED MYB-RELATED PROTEIN B RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell cycle#GO:0007049;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000004611.3|UniProtKB=G3QPM2 G3QPM2 RASSF8 PTHR15286:SF9 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 8 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005322.3|UniProtKB=A0A2I2Z8B3 A0A2I2Z8B3 BBS5 PTHR21351:SF0 BARDET-BIEDL SYNDROME PROTEIN 5 BBSOME COMPLEX MEMBER BBS5 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031 intracellular membraneless organelle#GO:0043232;BBSome#GO:0034464;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000043232.1|UniProtKB=A0A2I2YYA3 A0A2I2YYA3 PTHR13452:SF14 THUMP DOMAIN CONTAINING PROTEIN 1-RELATED THUMP DOMAIN-CONTAINING PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000014651.3|UniProtKB=G3RFC4 G3RFC4 IL13RA1 PTHR23036:SF89 CYTOKINE RECEPTOR INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-1 cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000004650.3|UniProtKB=G3QPQ6 G3QPQ6 CD27 PTHR47496:SF1 CD27 CD27 ANTIGEN regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000036941.1|UniProtKB=A0A2I2ZHK9 A0A2I2ZHK9 PTHR13220:SF14 TIMELESS INTERACTING-RELATED TIMELESS-INTERACTING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage response#GO:0006974;metabolic process#GO:0008152;negative regulation of DNA-templated DNA replication#GO:2000104;negative regulation of cellular process#GO:0048523;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;DNA-templated DNA replication#GO:0006261;regulation of DNA replication#GO:0006275 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000015405.3|UniProtKB=A0A2I2Z5L9 A0A2I2Z5L9 USP6NL PTHR22957:SF193 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN USP6 N-TERMINAL-LIKE PROTEIN enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000004163.3|UniProtKB=A0A2I2ZS98 A0A2I2ZS98 CMTM2 PTHR22776:SF15 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;myelination#GO:0042552;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;myelin sheath#GO:0043209;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;cell periphery#GO:0071944;apical part of cell#GO:0045177 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000004.3|UniProtKB=G3S600 G3S600 DNAH9 PTHR46532:SF13 MALE FERTILITY FACTOR KL5 DYNEIN AXONEMAL HEAVY CHAIN 5 GORGO|Ensembl=ENSGGOG00000016527.3|UniProtKB=G3RK70 G3RK70 VIPAS39 PTHR13364:SF6 DEFECTIVE SPERMATOGENESIS PROTEIN 39 SPERMATOGENESIS-DEFECTIVE PROTEIN 39 HOMOLOG macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000007211.3|UniProtKB=G3QWA4 G3QWA4 BGN PTHR45712:SF11 AGAP008170-PA BIGLYCAN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000003601.3|UniProtKB=G3RMV4 G3RMV4 DTNA PTHR12268:SF19 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN ALPHA membrane#GO:0016020;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;plasma membrane#GO:0005886 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005021.3|UniProtKB=A0A2I2Z9R7 A0A2I2Z9R7 PTHR21032:SF3 G PATCH DOMAIN-CONTAINING PROTEIN 11 G PATCH DOMAIN-CONTAINING PROTEIN 11 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;multicellular organismal process#GO:0032501;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;system process#GO:0003008;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;visual perception#GO:0007601;nucleic acid metabolic process#GO:0090304;sensory perception of light stimulus#GO:0050953;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;sensory perception#GO:0007600;nervous system process#GO:0050877 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000016751.3|UniProtKB=G3SD87 G3SD87 DDX6 PTHR47960:SF2 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 ATP-DEPENDENT RNA HELICASE DDX6-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component biogenesis#GO:0044085;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;organelle assembly#GO:0070925;negative regulation of translation#GO:0017148;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of biological process#GO:0050789;P-body assembly#GO:0033962;regulation of macromolecule metabolic process#GO:0060255;cytoplasmic stress granule assembly#GO:0034063;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014188.3|UniProtKB=G3RE66 G3RE66 ZNF76 PTHR24393:SF185 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 76 transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013163.3|UniProtKB=G3RS87 G3RS87 RAB3GAP2 PTHR12472:SF1 RAB3-GAP REGULATORY DOMAIN RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 metabolic process#GO:0008152;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization to membrane#GO:0090150;synaptic signaling#GO:0099536;autophagy#GO:0006914;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to endoplasmic reticulum#GO:0072599;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;macroautophagy#GO:0016236;localization within membrane#GO:0051668;cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;catabolic process#GO:0009056;signaling#GO:0023052 organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;autophagosome#GO:0005776;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;vacuole#GO:0005773;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;synaptic membrane#GO:0097060;cell junction#GO:0030054 G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000009460.3|UniProtKB=G3R205 G3R205 RPL36A PTHR10369:SF6 60S RIBOSOMAL PROTEIN L36A/L44 LARGE RIBOSOMAL SUBUNIT PROTEIN EL42 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001489.3|UniProtKB=G3QGL4 G3QGL4 CAPN10 PTHR10183:SF30 CALPAIN CALPAIN-10 peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000010814.3|UniProtKB=G3R5G8 G3R5G8 TNFSF15 PTHR11471:SF24 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell communication#GO:0007154;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000008444.3|UniProtKB=G3QZF5 G3QZF5 PTHR13020:SF32 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6B PROTEIN negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007558.3|UniProtKB=G3QX64 G3QX64 BHMT PTHR46120:SF2 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000010920.3|UniProtKB=G3R5R2 G3R5R2 LOC101124243 PTHR18034:SF4 CELL CYCLE CONTROL PROTEIN CWF22-RELATED NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000008859.4|UniProtKB=G3R0I1 G3R0I1 BRIP1 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678 nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;response to stimulus#GO:0050896;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;DNA damage response#GO:0006974;reproductive process#GO:0022414;homologous recombination#GO:0035825;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000036671.1|UniProtKB=A0A2I2ZKP1 A0A2I2ZKP1 PTHR21245:SF14 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RRM DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008091.3|UniProtKB=G3QYH7 G3QYH7 VPS36 PTHR13128:SF12 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;establishment of protein localization to vacuole#GO:0072666;protein transport#GO:0015031;cellular localization#GO:0051641;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;localization#GO:0051179;protein localization to vacuole#GO:0072665;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000016579.3|UniProtKB=G3RKB3 G3RKB3 UBE3D PTHR31531:SF2 E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE E3D ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;cyclin binding#GO:0030332;catalytic activity#GO:0003824;transferase activity#GO:0016740 catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015034.3|UniProtKB=G3RGD0 G3RGD0 PTHR11430:SF64 LIPOCALIN LIPOCALIN-15 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000013627.3|UniProtKB=A0A2I2YEK3 A0A2I2YEK3 TBCE PTHR15140:SF31 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE E protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000012393.3|UniProtKB=P61638 P61638 COX7C PTHR13313:SF1 CYTOCHROME C OXIDASE SUBUNIT VIIC CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900 cytochrome complex#GO:0070069;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transporter complex#GO:1990351 oxidoreductase#PC00176;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000012961.3|UniProtKB=G3RXU8 G3RXU8 LYPD3 PTHR10624:SF8 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR-RELATED LY6_PLAUR DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001023.3|UniProtKB=G3QFD8 G3QFD8 KLK5 PTHR24271:SF59 KALLIKREIN-RELATED KALLIKREIN-5 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000027715.2|UniProtKB=G3RQE4 G3RQE4 LOC101133344 PTHR26453:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015420.3|UniProtKB=G3RHD1 G3RHD1 PTDSS2 PTHR15362:SF7 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 2 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000042486.1|UniProtKB=A0A2I2ZFG3 A0A2I2ZFG3 LOC101129681 PTHR24062:SF181 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 4 binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025575.2|UniProtKB=G3SGD1 G3SGD1 MIF PTHR11954:SF49 D-DOPACHROME DECARBOXYLASE MACROPHAGE MIGRATION INHIBITORY FACTOR signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lyase#PC00144;metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 GORGO|Ensembl=ENSGGOG00000016433.3|UniProtKB=G3SDM6 G3SDM6 ATG16L1 PTHR19878:SF6 AUTOPHAGY PROTEIN 16-LIKE AUTOPHAGY-RELATED PROTEIN 16-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 organelle assembly#GO:0070925;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;catabolic process#GO:0009056 vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000040832.1|UniProtKB=A0A2I2Z6T3 A0A2I2Z6T3 PTHR46756:SF30 TRANSGELIN CALPONIN-2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;protein localization to organelle#GO:0033365;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;microtubule bundle formation#GO:0001578;actin filament-based process#GO:0030029;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;supramolecular fiber organization#GO:0097435;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;protein localization to microtubule cytoskeleton#GO:0072698;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;intracellular protein localization#GO:0008104;actin filament organization#GO:0007015 stress fiber#GO:0001725;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;actomyosin#GO:0042641;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;microtubule#GO:0005874;microtubule end#GO:1990752;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000003288.3|UniProtKB=G3QL84 G3QL84 ACSM4 PTHR43605:SF8 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM4, MITOCHONDRIAL ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;acyltransferase activity#GO:0016746;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 ligase#PC00142;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000028150.2|UniProtKB=G3S216 G3S216 LOC101144085 PTHR48001:SF70 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1D4-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027180.2|UniProtKB=G3RY07 G3RY07 PTHR26450:SF177 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52I1-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026724.2|UniProtKB=G3S901 G3S901 SHISA3 PTHR31395:SF4 SHISA PROTEIN SHISA-3 HOMOLOG scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026124.2|UniProtKB=G3RTM2 G3RTM2 XKR9 PTHR16024:SF13 XK-RELATED PROTEIN XK-RELATED PROTEIN 9 endomembrane system organization#GO:0010256;cellular process#GO:0009987;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;membrane invagination#GO:0010324;endocytosis#GO:0006897;cellular component organization#GO:0016043;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;lipid transport#GO:0006869;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;phagocytosis#GO:0006909;developmental process#GO:0032502;transport#GO:0006810;organophosphate ester transport#GO:0015748;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;programmed cell death#GO:0012501;cell death#GO:0008219;localization#GO:0051179;anatomical structure development#GO:0048856 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000006228.3|UniProtKB=G3RM04 G3RM04 CRYBB2 PTHR11818:SF11 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B2 structural molecule activity#GO:0005198 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000006088.3|UniProtKB=A0A2I2YU49 A0A2I2YU49 YWHAH PTHR18860:SF16 14-3-3 PROTEIN 14-3-3 PROTEIN ETA scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;Parkinson disease#P00049>14-3-3#P01238 GORGO|Ensembl=ENSGGOG00000013398.3|UniProtKB=G3RC50 G3RC50 NPAS1 PTHR23043:SF25 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000002657.3|UniProtKB=G3QJL9 G3QJL9 GPR84 PTHR24230:SF59 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 84 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007836.3|UniProtKB=G3QXU5 G3QXU5 ANKS4B PTHR24161:SF20 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 4B localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;cellular component assembly#GO:0022607;protein localization to organelle#GO:0033365;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;cellular process#GO:0009987 actin-based cell projection#GO:0098858;cell periphery#GO:0071944;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;membrane#GO:0016020;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008566.3|UniProtKB=G3QZQ8 G3QZQ8 PACSIN3 PTHR23065:SF18 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 3 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 regulation of biological process#GO:0050789;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000043168.1|UniProtKB=A0A2I2ZD90 A0A2I2ZD90 PTHR23266:SF223 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-7 antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000043773.1|UniProtKB=A0A2I2Z1Q8 A0A2I2Z1Q8 DIRAS3 PTHR24070:SF269 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS3 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000028128.2|UniProtKB=A0A2I2ZGL5 A0A2I2ZGL5 PTHR22055:SF3 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN CASEIN KINASE SUBSTRATE PHOSPHOPROTEIN PP28 DOMAIN-CONTAINING PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000000403.3|UniProtKB=G3SGF8 G3SGF8 LACTB2 PTHR23131:SF6 ENDORIBONUCLEASE LACTB2 ENDORIBONUCLEASE LACTB2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;single-stranded RNA binding#GO:0003727;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000040937.1|UniProtKB=A0A2I2Z691 A0A2I2Z691 NOL12 PTHR14577:SF0 NUCLEOLAR PROTEIN 12 NUCLEOLAR PROTEIN 12 RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000023181.2|UniProtKB=G3RRZ4 G3RRZ4 ELOVL7 PTHR11157:SF118 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 7 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000003454.3|UniProtKB=G3QLN5 G3QLN5 GLDN PTHR23192:SF85 OLFACTOMEDIN-RELATED GLIOMEDIN cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000042976.1|UniProtKB=A0A2I2Z2W4 A0A2I2Z2W4 STAT4 PTHR11801:SF19 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 4 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cytokine-mediated signaling pathway#GO:0019221;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to peptide hormone#GO:0043434;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of biosynthetic process#GO:0009889;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;response to hormone#GO:0009725;cell surface receptor signaling pathway via STAT#GO:0097696;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Interleukin signaling pathway#P00036>STAT#P00996;PDGF signaling pathway#P00047>STAT#P01173;EGF receptor signaling pathway#P00018>STAT#P00561;JAK/STAT signaling pathway#P00038>STAT#P01027 GORGO|Ensembl=ENSGGOG00000042280.1|UniProtKB=A0A2I2ZLW0 A0A2I2ZLW0 PTHR24055:SF171 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 6 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>MEK#P01402;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interleukin signaling pathway#P00036>ERK#P00965;Integrin signalling pathway#P00034>ERK#P00907 GORGO|Ensembl=ENSGGOG00000007014.3|UniProtKB=G3QVT1 G3QVT1 PNPLA1 PTHR12406:SF23 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED OMEGA-HYDROXYCERAMIDE TRANSACYLASE carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;triacylglycerol lipase activity#GO:0004806;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 neutral lipid catabolic process#GO:0046461;ceramide biosynthetic process#GO:0046513;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;acylglycerol metabolic process#GO:0006639;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;lipid catabolic process#GO:0016042;cellular process#GO:0009987;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;triglyceride catabolic process#GO:0019433;glycerolipid catabolic process#GO:0046503;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056 intracellular organelle#GO:0043229;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000002708.3|UniProtKB=G3QJR8 G3QJR8 TM7SF2 PTHR21257:SF59 DELTA(14)-STEROL REDUCTASE DELTA(14)-STEROL REDUCTASE TM7SF2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;secondary alcohol biosynthetic process#GO:1902653;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;organelle inner membrane#GO:0019866;nucleus#GO:0005634;membrane#GO:0016020;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000013825.3|UniProtKB=G3RD94 G3RD94 LOXL2 PTHR45817:SF1 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 2 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;collagen fibril organization#GO:0030199;external encapsulating structure organization#GO:0045229;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;circulatory system development#GO:0072359;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tube development#GO:0035295 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 oxidoreductase#PC00176;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000027404.2|UniProtKB=G3S7Q5 G3S7Q5 XAGE3 PTHR14047:SF4 P ANTIGEN FAMILY MEMBER 5-RELATED X ANTIGEN FAMILY MEMBER 3 GORGO|Ensembl=ENSGGOG00000010764.3|UniProtKB=G3R5C9 G3R5C9 SLC25A22 PTHR45678:SF3 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED MITOCHONDRIAL GLUTAMATE CARRIER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000004781.3|UniProtKB=G3QQ25 G3QQ25 STMN2 PTHR10104:SF18 STATHMIN STATHMIN-2 binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;protein depolymerization#GO:0051261;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;microtubule polymerization or depolymerization#GO:0031109;system development#GO:0048731;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;regulation of microtubule-based process#GO:0032886;protein-containing complex disassembly#GO:0032984;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;neuron development#GO:0048666;cellular component disassembly#GO:0022411;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043 axon#GO:0030424;growth cone#GO:0030426;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;neuron projection#GO:0043005;cell projection#GO:0042995;distal axon#GO:0150034;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000025069.2|UniProtKB=G3RY30 G3RY30 PDIA4 PTHR18929:SF210 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A4 isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 response to stimulus#GO:0050896;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000003695.3|UniProtKB=G3QMA1 G3QMA1 RPL4 PTHR19431:SF5 60S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4 structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000013904.3|UniProtKB=G3RDF8 G3RDF8 TBX4 PTHR11267:SF29 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;tube development#GO:0035295;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cell fate specification#GO:0001708;cellular process#GO:0009987;cell fate commitment#GO:0045165;angiogenesis#GO:0001525;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 GORGO|Ensembl=ENSGGOG00000004635.3|UniProtKB=A0A2I2ZWD7 A0A2I2ZWD7 SCRIB PTHR23119:SF57 DISCS LARGE PROTEIN SCRIBBLE HOMOLOG signaling adaptor activity#GO:0035591;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;endosome to plasma membrane protein transport#GO:0099638;cell migration#GO:0016477;biological regulation#GO:0065007;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to cell junction#GO:1902414;establishment or maintenance of bipolar cell polarity#GO:0061245;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;cell motility#GO:0048870;protein localization to cell periphery#GO:1990778;intracellular protein transport#GO:0006886;protein localization to synapse#GO:0035418;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;endosomal transport#GO:0016197;cell-cell adhesion#GO:0098609;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;establishment or maintenance of cell polarity#GO:0007163;receptor clustering#GO:0043113;cell adhesion#GO:0007155;cellular localization#GO:0051641;protein transport#GO:0015031;regulation of biological quality#GO:0065008;protein localization to membrane#GO:0072657;endocytic recycling#GO:0032456 postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;anchoring junction#GO:0070161;postsynapse#GO:0098794;basal part of cell#GO:0045178;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;synaptic membrane#GO:0097060;cell junction#GO:0030054;adherens junction#GO:0005912;cell-cell junction#GO:0005911;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000024238.2|UniProtKB=G3S132 G3S132 PTHR23222:SF16 PROHIBITIN PROHIBITIN cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003187.3|UniProtKB=A0A2I2YP89 A0A2I2YP89 MMS22L PTHR28547:SF1 PROTEIN MMS22-LIKE PROTEIN MMS22-LIKE response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000005483.3|UniProtKB=G3QRV4 G3QRV4 PTHR23267:SF362 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000040199.1|UniProtKB=A0A2I2YP87 A0A2I2YP87 PTHR48092:SF4 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN RELATED RECEPTOR ALPHA transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000010551.3|UniProtKB=G3S1J2 G3S1J2 BCL2L13 PTHR15758:SF2 BCL-2-LIKE PROTEIN 13 BCL-2-LIKE PROTEIN 13 GORGO|Ensembl=ENSGGOG00000012589.3|UniProtKB=G3RA22 G3RA22 RIPK1 PTHR44329:SF6 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 programmed cell death#GO:0012501;necroptotic process#GO:0070266;cellular process#GO:0009987;cell death#GO:0008219;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>RIP#P00315 GORGO|Ensembl=ENSGGOG00000001053.3|UniProtKB=G3QFG8 G3QFG8 RAD50 PTHR18867:SF12 RAD50 DNA REPAIR PROTEIN RAD50 sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;telomeric repeat DNA binding#GO:0042162;DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;telomere maintenance via telomerase#GO:0007004;telomere maintenance via telomere lengthening#GO:0010833;DNA recombination#GO:0006310;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reproductive process#GO:0022414;sexual reproduction#GO:0019953;mitotic recombination#GO:0006312;telomere organization#GO:0032200;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA damage response#GO:0006974;RNA-templated DNA biosynthetic process#GO:0006278;DNA repair#GO:0006281;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000005179.3|UniProtKB=G3RWY1 G3RWY1 APOB PTHR13769:SF1 APOLIPOPROTEIN B APOLIPOPROTEIN B-100 protein binding#GO:0005515;lipid transfer activity#GO:0120013;lipoprotein particle receptor binding#GO:0070325;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;binding#GO:0005488;signaling receptor binding#GO:0005102;cholesterol transfer activity#GO:0120020;transporter activity#GO:0005215;sterol transfer activity#GO:0120015 lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;homeostatic process#GO:0042592;lipid localization#GO:0010876;localization#GO:0051179;protein transport#GO:0015031;organic hydroxy compound transport#GO:0015850;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;lipid transport#GO:0006869;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;triglyceride metabolic process#GO:0006641;transport#GO:0006810;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;sterol transport#GO:0015918;neutral lipid metabolic process#GO:0006638;intracellular protein localization#GO:0008104 very-low-density lipoprotein particle#GO:0034361;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;extracellular region#GO:0005576;lipoprotein particle#GO:1990777;plasma lipoprotein particle#GO:0034358 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000006562.3|UniProtKB=G3QW78 G3QW78 WNT3A PTHR12027:SF88 WNT RELATED PROTEIN WNT-3A protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664 multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell fate commitment#GO:0045165;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 GORGO|Ensembl=ENSGGOG00000007229.3|UniProtKB=G3QWC9 G3QWC9 TFRC PTHR10404:SF26 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE TRANSFERRIN RECEPTOR PROTEIN 1 peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000012373.3|UniProtKB=G3SDP7 G3SDP7 PTHR45027:SF5 PUTATIVE GLUTATHIONE HYDROLASE LIGHT CHAIN GLUTATHIONE HYDROLASE LIGHT CHAIN 2-RELATED hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000009081.3|UniProtKB=G3R125 G3R125 C3H4orf33 PTHR31475:SF3 UPF0462 PROTEIN UPF0462 PROTEIN C4ORF33 GORGO|Ensembl=ENSGGOG00000006731.3|UniProtKB=A0A2I2YPN0 A0A2I2YPN0 LOC101132862 PTHR11783:SF73 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1C2 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000000460.3|UniProtKB=G3QDX2 G3QDX2 RDH13 PTHR43157:SF59 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 13 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure formation involved in morphogenesis#GO:0048646;metabolic process#GO:0008152;neuron differentiation#GO:0030182;retina development in camera-type eye#GO:0060041;nervous system development#GO:0007399;sensory system development#GO:0048880;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;neuron development#GO:0048666;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;olefinic compound metabolic process#GO:0120254;generation of neurons#GO:0048699;cell differentiation#GO:0030154;sensory organ morphogenesis#GO:0090596;cell development#GO:0048468;anatomical structure morphogenesis#GO:0009653;retinoid metabolic process#GO:0001523;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;diterpenoid metabolic process#GO:0016101;sensory organ development#GO:0007423;developmental process#GO:0032502;lipid metabolic process#GO:0006629;multicellular organismal process#GO:0032501;camera-type eye morphogenesis#GO:0048593;anatomical structure development#GO:0048856;isoprenoid metabolic process#GO:0006720;system development#GO:0048731;camera-type eye development#GO:0043010;terpenoid metabolic process#GO:0006721;animal organ morphogenesis#GO:0009887;visual system development#GO:0150063;primary metabolic process#GO:0044238 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000012937.3|UniProtKB=A0A2I2YYN4 A0A2I2YYN4 SSTR1 PTHR24229:SF38 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 1 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neuropeptide receptor activity#GO:0008188;binding#GO:0005488;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to estradiol#GO:0032355;biological regulation#GO:0065007;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 GORGO|Ensembl=ENSGGOG00000010222.3|UniProtKB=A0A2I2Z6H2 A0A2I2Z6H2 PTHR24416:SF66 TYROSINE-PROTEIN KINASE RECEPTOR NT-3 GROWTH FACTOR RECEPTOR phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cell differentiation#GO:0030154;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular response to nerve growth factor stimulus#GO:1990090;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008 axon#GO:0030424;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000042843.1|UniProtKB=A0A2I2YVT6 A0A2I2YVT6 CDKN2B PTHR24201:SF8 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR B enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914 regulation of cell population proliferation#GO:0042127;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;negative regulation of cell population proliferation#GO:0008285;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 p53 pathway#P00059>ARF#G01574 GORGO|Ensembl=ENSGGOG00000004849.3|UniProtKB=G3QQ88 G3QQ88 LOC101148074 PTHR23260:SF2 KERATIN ASSOCIATED PROTEIN 3-3-RELATED KERATIN-ASSOCIATED PROTEIN 24-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000003605.3|UniProtKB=G3QM18 G3QM18 TM4SF1 PTHR14198:SF18 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004210.3|UniProtKB=G3QNN8 G3QNN8 DNAH10 PTHR22878:SF63 DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED DYNEIN HEAVY CHAIN 10, AXONEMAL Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000037871.1|UniProtKB=A0A2I2Y807 A0A2I2Y807 PTHR19433:SF120 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 30 response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008188.3|UniProtKB=G3QYR3 G3QYR3 KLF8 PTHR23235:SF46 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000026423.2|UniProtKB=G3SJD8 G3SJD8 TARM1 PTHR11738:SF157 MHC CLASS I NK CELL RECEPTOR T-CELL-INTERACTING, ACTIVATING RECEPTOR ON MYELOID CELLS PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of cell adhesion#GO:0007162;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;negative regulation of cell population proliferation#GO:0008285;negative regulation of cell activation#GO:0050866;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of T cell proliferation#GO:0042129;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;negative regulation of multicellular organismal process#GO:0051241;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;negative regulation of T cell activation#GO:0050868;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mononuclear cell proliferation#GO:0032944;negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000000938.3|UniProtKB=G3S6X6 G3S6X6 SIAH1 PTHR45877:SF7 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH1 ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433;p53 pathway#P00059>Siah#G04696;p53 pathway feedback loops 2#P04398>SIAH-1#P04660;p53 pathway feedback loops 2#P04398>SIAH-1#G04711 GORGO|Ensembl=ENSGGOG00000022994.2|UniProtKB=G3S7B3 G3S7B3 CDK5RAP3 PTHR14894:SF2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to unfolded protein#GO:0006986;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008711.3|UniProtKB=G3R041 G3R041 OAF PTHR13423:SF2 OUT AT FIRST OUT AT FIRST PROTEIN HOMOLOG GORGO|Ensembl=ENSGGOG00000015424.3|UniProtKB=G3RHD2 G3RHD2 ANKRD35 PTHR24161:SF21 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 35 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012310.3|UniProtKB=G3R9E1 G3R9E1 ESYT2 PTHR45761:SF2 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-2 lipid binding#GO:0008289;cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylcholine binding#GO:0031210;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000013022.3|UniProtKB=G3RB65 G3RB65 PCED1B PTHR14469:SF1 SARCOMA ANTIGEN NY-SAR-23 PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1B GORGO|Ensembl=ENSGGOG00000016683.3|UniProtKB=A0A2I2YG79 A0A2I2YG79 CELSR3 PTHR24028:SF326 CADHERIN-87A CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 3 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000011125.3|UniProtKB=G3R6A2 G3R6A2 PTHR11071:SF596 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000039649.1|UniProtKB=A0A2I2ZYC0 A0A2I2ZYC0 PTHR21139:SF47 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;ATP metabolic process#GO:0046034;aldehyde metabolic process#GO:0006081;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;oxoacid metabolic process#GO:0043436;glyceraldehyde-3-phosphate metabolic process#GO:0019682;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;nucleoside diphosphate catabolic process#GO:0009134;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate biosynthetic process#GO:0016051;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;pyruvate metabolic process#GO:0006090;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141 isomerase#PC00135;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000015661.3|UniProtKB=G3RI02 G3RI02 PTHR15036:SF17 PIKACHURIN-LIKE PROTEIN CHONDROITIN SULFATE PROTEOGLYCAN 4 developmental process#GO:0032502;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000010965.3|UniProtKB=G3R5V5 G3R5V5 PSMB9 PTHR11599:SF50 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-9 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000005528.3|UniProtKB=G3QRZ8 G3QRZ8 ZSCAN31 PTHR23226:SF132 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 31 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008003.3|UniProtKB=G3RSD2 G3RSD2 ACOX3 PTHR10909:SF390 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 3 oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;lipid binding#GO:0008289;anion binding#GO:0043168;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;organic acid binding#GO:0043177 lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000023036.2|UniProtKB=Q2QD07 Q2QD07 TPI1 PTHR21139:SF24 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 carbohydrate derivative biosynthetic process#GO:1901137;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;aldehyde metabolic process#GO:0006081;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;glyceraldehyde-3-phosphate metabolic process#GO:0019682;oxoacid metabolic process#GO:0043436;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;energy derivation by oxidation of organic compounds#GO:0015980;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;hexose biosynthetic process#GO:0019319;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;carbohydrate biosynthetic process#GO:0016051;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyruvate metabolic process#GO:0006090;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Triosephosphate isomerase#P00673 GORGO|Ensembl=ENSGGOG00000001972.3|UniProtKB=A0A2I2ZL86 A0A2I2ZL86 GYS1 PTHR10176:SF2 GLYCOGEN SYNTHASE GLYCOGEN [STARCH] SYNTHASE, MUSCLE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;glycogen biosynthetic process#GO:0005978;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glucan biosynthetic process#GO:0009250;energy reserve metabolic process#GO:0006112;polysaccharide biosynthetic process#GO:0000271;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Glycogen synthase D#P00709 GORGO|Ensembl=ENSGGOG00000009226.3|UniProtKB=G3R1H8 G3R1H8 NBAS PTHR15922:SF2 NEUROBLASTOMA-AMPLIFIED SEQUENCE NBAS SUBUNIT OF NRZ TETHERING COMPLEX protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013868.3|UniProtKB=A0A2I2YVQ2 A0A2I2YVQ2 WDR24 PTHR46200:SF1 GATOR COMPLEX PROTEIN WDR24 GATOR2 COMPLEX PROTEIN WDR24 regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;positive regulation of macroautophagy#GO:0016239;response to stimulus#GO:0050896;regulation of macroautophagy#GO:0016241;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;cellular response to amino acid starvation#GO:0034198;positive regulation of TOR signaling#GO:0032008;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;positive regulation of TORC1 signaling#GO:1904263;response to nutrient levels#GO:0031667;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;Seh1-associated complex#GO:0035859;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 GORGO|Ensembl=ENSGGOG00000011511.3|UniProtKB=G3R794 G3R794 SLC35B3 PTHR10778:SF8 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;purine nucleotide transmembrane transporter activity#GO:0015216;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000013539.3|UniProtKB=G3RCH7 G3RCH7 NSFL1C PTHR23333:SF24 UBX DOMAIN CONTAINING PROTEIN NSFL1 COFACTOR P47 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;establishment of spindle localization#GO:0051293;localization#GO:0051179;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;organelle localization#GO:0051640;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;primary metabolic process#GO:0044238;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;positive regulation of cell cycle#GO:0045787;proteasomal protein catabolic process#GO:0010498;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;cellular localization#GO:0051641;spindle localization#GO:0051653;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment or maintenance of cell polarity#GO:0007163;regulation of cell cycle#GO:0051726;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cell cycle process#GO:0022402;cellular component organization#GO:0016043 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000041124.1|UniProtKB=A0A2I2Z5S4 A0A2I2Z5S4 PTHR12888:SF1 PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12 PEROXISOME ASSEMBLY PROTEIN 12 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 peroxisome organization#GO:0007031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840 peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000015501.3|UniProtKB=G3SGW1 G3SGW1 DISP3 PTHR46687:SF1 PROTEIN DISPATCHED HOMOLOG 3 PROTEIN DISPATCHED HOMOLOG 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000043297.1|UniProtKB=A0A2I2Z578 A0A2I2Z578 PTHR13678:SF19 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VPS37 C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein targeting to vacuole#GO:0006623;establishment of protein localization to membrane#GO:0090150;intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;protein targeting to membrane#GO:0006612;metabolic process#GO:0008152;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein transport#GO:0015031;cellular localization#GO:0051641;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;localization within membrane#GO:0051668;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179 membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000005431.3|UniProtKB=G3QRQ6 G3QRQ6 ZNF18 PTHR23226:SF190 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 18 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024304.2|UniProtKB=G3RRX9 G3RRX9 SFT2D1 PTHR23137:SF24 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2A GORGO|Ensembl=ENSGGOG00000000114.3|UniProtKB=A0A2I2Z6L3 A0A2I2Z6L3 GRIK2 PTHR18966:SF38 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;carboxylic acid transmembrane transporter activity#GO:0046943;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;signaling receptor activity#GO:0038023;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794 presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;transporter complex#GO:1990351;cell junction#GO:0030054;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;postsynaptic density membrane#GO:0098839;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA2#P01003;Ionotropic glutamate receptor pathway#P00037>KA#P01026;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 GORGO|Ensembl=ENSGGOG00000024299.2|UniProtKB=G3RT63 G3RT63 ELMOD2 PTHR12771:SF47 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 2 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 cilium organization#GO:0044782;organelle assembly#GO:0070925;regulation of defense response#GO:0031347;cell projection organization#GO:0030030;regulation of response to biotic stimulus#GO:0002831;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of response to stress#GO:0080134;plasma membrane bounded cell projection assembly#GO:0120031;regulation of response to stimulus#GO:0048583;regulation of response to external stimulus#GO:0032101;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040607.1|UniProtKB=A0A2I2YHI8 A0A2I2YHI8 OST4 PTHR48164:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4 protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003326.3|UniProtKB=G3QLC0 G3QLC0 ZNF778 PTHR24381:SF153 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 778 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000038002.1|UniProtKB=A0A2I2YME8 A0A2I2YME8 PTHR12297:SF14 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;negative regulation of apoptotic process#GO:0043066;cellular component assembly#GO:0022607;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037115.1|UniProtKB=A0A2I2YCT1 A0A2I2YCT1 PTHR12138:SF133 PRIMATE-EXPANDED PROTEIN FAMILY SECRETED PROTEIN GORGO|Ensembl=ENSGGOG00000041295.1|UniProtKB=A0A2I2ZKS3 A0A2I2ZKS3 PIRT PTHR16100:SF4 PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER PHOSPHOINOSITIDE-INTERACTING PROTEIN transmembrane transporter binding#GO:0044325;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936 regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of system process#GO:0044057 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000036539.1|UniProtKB=A0A2I2ZA38 A0A2I2ZA38 LOC101134803 PTHR23105:SF186 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008377.3|UniProtKB=G3QZ84 G3QZ84 SLC29A1 PTHR10332:SF9 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337;carbohydrate derivative transmembrane transporter activity#GO:1901505 nucleobase-containing compound transport#GO:0015931;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008432.3|UniProtKB=G3QZE3 G3QZE3 LAMB3 PTHR10574:SF268 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-3 cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;substrate adhesion-dependent cell spreading#GO:0034446;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;neuron development#GO:0048666;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;extracellular matrix assembly#GO:0085029;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cell migration#GO:0016477;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell motility#GO:0048870;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;system development#GO:0048731;external encapsulating structure organization#GO:0045229 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000006251.3|UniProtKB=G3QTT5 G3QTT5 WDR76 PTHR14773:SF0 WD REPEAT-CONTAINING PROTEIN 76 WD REPEAT-CONTAINING PROTEIN 76 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of signal transduction#GO:0009966;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of intracellular signal transduction#GO:1902531;regulation of cellular response to stress#GO:0080135 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009233.3|UniProtKB=A0A2I2ZDM6 A0A2I2ZDM6 LOC101152998 PTHR10655:SF13 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 2 catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity#GO:0016787;palmitoyl hydrolase activity#GO:0098599;thiolester hydrolase activity#GO:0016790;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of transport#GO:0051051;catabolic process#GO:0009056;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of protein localization to membrane#GO:1905475;lipid catabolic process#GO:0016042;cellular process#GO:0009987;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;regulation of localization#GO:0032879;regulation of transport#GO:0051049 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 phospholipase#PC00186;lipase#PC00143 GORGO|Ensembl=ENSGGOG00000037558.1|UniProtKB=A0A2I2ZHU7 A0A2I2ZHU7 MYOZ3 PTHR15941:SF15 MYOZENIN MYOZENIN-3 molecular condensate scaffold activity#GO:0140693;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular anatomical entity morphogenesis#GO:0032989;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;striated muscle cell development#GO:0055002;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;response to stimulus#GO:0050896;actomyosin structure organization#GO:0031032;cell development#GO:0048468;developmental process#GO:0032502;cellular developmental process#GO:0048869;system process#GO:0003008;skeletal muscle tissue development#GO:0007519;multicellular organismal process#GO:0032501;tissue development#GO:0009888;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;cellular response to stimulus#GO:0051716;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036 intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000001564.3|UniProtKB=A0A2I2YB47 A0A2I2YB47 GAPVD1 PTHR23101:SF25 RAB GDP/GTP EXCHANGE FACTOR GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000038900.1|UniProtKB=A0A2I2YHI0 A0A2I2YHI0 PTHR23266:SF357 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-11-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000016339.3|UniProtKB=A0A2I2Z246 A0A2I2Z246 C20H19orf44 PTHR22409:SF2 CHROMOSOME 19 OPEN READING FRAME 44 CHROMOSOME 19 OPEN READING FRAME 44 GORGO|Ensembl=ENSGGOG00000000139.3|UniProtKB=A0A2I2YZ03 A0A2I2YZ03 RNFT2 PTHR15860:SF2 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNFT2 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 GORGO|Ensembl=ENSGGOG00000010310.4|UniProtKB=G3R472 G3R472 TMEM255A PTHR33721:SF1 TRANSMEMBRANE PROTEIN 255B-LIKE TRANSMEMBRANE PROTEIN 255A GORGO|Ensembl=ENSGGOG00000000999.3|UniProtKB=G3QFB9 G3QFB9 PTHR11686:SF56 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 1 PROENZYME-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;sulfur compound catabolic process#GO:0044273;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;regulation of immune system process#GO:0002682;catabolic process#GO:0009056;regulation of biological process#GO:0050789;modified amino acid metabolic process#GO:0006575;peptide metabolic process#GO:0006518;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;glutathione metabolic process#GO:0006749 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011898.3|UniProtKB=G3R8A5 G3R8A5 PUS7 PTHR13326:SF31 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE 7 HOMOLOG catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;pseudouridine synthesis#GO:0001522;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;RNA modification#GO:0009451;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000042217.1|UniProtKB=A0A2I2YXM1 A0A2I2YXM1 APOBEC4 PTHR35672:SF1 C-U-EDITING ENZYME APOBEC-4-RELATED DEAMINASE APOBEC-4-RELATED GORGO|Ensembl=ENSGGOG00000026029.2|UniProtKB=G3RVY7 G3RVY7 LOC101140002 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 chromatin binding#GO:0003682;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000039407.1|UniProtKB=A0A2I2ZRG2 A0A2I2ZRG2 NUDT3 PTHR12629:SF5 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 alcohol metabolic process#GO:0006066;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000039680.1|UniProtKB=A0A2I2Z539 A0A2I2Z539 PTHR15591:SF16 RUN AND SH3 DOMAIN CONTAINING FARNESYL PYROPHOSPHATE SYNTHASE vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000001629.3|UniProtKB=G3QGY9 G3QGY9 HOXC5 PTHR45659:SF5 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-C5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000005460.3|UniProtKB=G3QRT2 G3QRT2 TCF21 PTHR23349:SF67 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 21 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010694.3|UniProtKB=G3R568 G3R568 EFCAB5 PTHR46788:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 cellular process#GO:0009987;sperm motility#GO:0097722;reproductive process#GO:0022414;cell motility#GO:0048870 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000041026.1|UniProtKB=G3S282 G3S282 ZNF8 PTHR24377:SF622 IP01015P-RELATED ZINC FINGER PROTEIN 8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000003460.3|UniProtKB=G3QLP8 G3QLP8 DLGAP5 PTHR12353:SF1 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 5 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;centrosome localization#GO:0051642;regulation of cell cycle#GO:0051726;mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization involved in mitosis#GO:1902850;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;kinetochore organization#GO:0051383;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002355.3|UniProtKB=G3QIU8 G3QIU8 TM4SF18 PTHR14198:SF14 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 18 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005502.3|UniProtKB=G3QRX3 G3QRX3 RPL30 PTHR11449:SF1 RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN EL30 structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014349.3|UniProtKB=G3REK4 G3REK4 CBR3 PTHR43963:SF3 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE [NADPH] 3 oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000003468.3|UniProtKB=G3QLP6 G3QLP6 KCTD20 PTHR21637:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD20 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000040035.1|UniProtKB=A0A2I2YB68 A0A2I2YB68 PTHR12901:SF16 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 START DOMAIN-CONTAINING PROTEIN mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011249.3|UniProtKB=G3S3Q0 G3S3Q0 VSIG10L PTHR44427:SF5 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000022253.2|UniProtKB=A0A2I2YAK5 A0A2I2YAK5 TAX1BP1 PTHR31915:SF8 SKICH DOMAIN-CONTAINING PROTEIN TAX1-BINDING PROTEIN 1 regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 GORGO|Ensembl=ENSGGOG00000005805.3|UniProtKB=G3QSP3 G3QSP3 GNB2 PTHR19850:SF27 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-2 signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737 heterotrimeric G-protein#PC00117;G-protein#PC00020;protein-binding activity modulator#PC00095 Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Wnt signaling pathway#P00057>GBeta#P01457;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;PI3 kinase pathway#P00048>Gbetagamma#P01188;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Enkephalin release#P05913>G-Protein (i)#P05974;GABA-B receptor II signaling#P05731>Gbeta#P05755;Enkephalin release#P05913>G-Protein (s)#P05977;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085 GORGO|Ensembl=ENSGGOG00000011379.3|UniProtKB=G3R6X3 G3R6X3 RGS7BP PTHR21029:SF12 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G PROTEIN SIGNALING 7-BINDING PROTEIN signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection#GO:0043005;nucleus#GO:0005634;postsynapse#GO:0098794 GORGO|Ensembl=ENSGGOG00000024159.2|UniProtKB=A0A2I2YS92 A0A2I2YS92 PTHR24068:SF214 UBIQUITIN-CONJUGATING ENZYME E2 UBC CORE DOMAIN-CONTAINING PROTEIN ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 regulation of chromosome segregation#GO:0051983;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of cell cycle phase transition#GO:1901987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000031.3|UniProtKB=G3QCT4 G3QCT4 P2RY1 PTHR24231:SF2 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 1 signaling receptor activity#GO:0038023;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;G protein-coupled receptor binding#GO:0001664;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;small molecule binding#GO:0036094;anion binding#GO:0043168;signaling receptor binding#GO:0005102;ion binding#GO:0043167 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000036207.1|UniProtKB=A0A2I2YCL3 A0A2I2YCL3 RFESD PTHR21496:SF0 FERREDOXIN-RELATED RIESKE DOMAIN-CONTAINING PROTEIN iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000015864.3|UniProtKB=G3RIG8 G3RIG8 BHLHE40 PTHR10985:SF3 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 40 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of neurogenesis#GO:0050767;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;negative regulation of DNA-templated transcription#GO:0045892;rhythmic process#GO:0048511;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000015442.3|UniProtKB=G3RHE7 G3RHE7 SFXN3 PTHR11153:SF20 SIDEROFLEXIN SIDEROFLEXIN-3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;intracellular transport#GO:0046907;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000040152.1|UniProtKB=G3QKC7 G3QKC7 H2AC20 PTHR23430:SF42 HISTONE H2A HISTONE H2A TYPE 2-A structural molecule activity#GO:0005198 regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000002317.3|UniProtKB=A0A2I2Y381 A0A2I2Y381 PPT2 PTHR11247:SF27 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 LYSOSOMAL THIOESTERASE PPT2 intracellular organelle#GO:0043229;extracellular region#GO:0005576;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000044197.1|UniProtKB=G3SCC9 G3SCC9 LOC101141136 PTHR45810:SF15 HISTONE H3.2 HISTONE H3 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000024205.2|UniProtKB=G3RX47 G3RX47 POLE2 PTHR12708:SF0 DNA POLYMERASE EPSILON SUBUNIT B DNA POLYMERASE EPSILON SUBUNIT 2 nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA synthesis involved in DNA replication#GO:0090592;DNA-templated DNA replication#GO:0006261;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;nuclear protein-containing complex#GO:0140513;epsilon DNA polymerase complex#GO:0008622;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA-directed DNA polymerase#PC00018 GORGO|Ensembl=ENSGGOG00000039033.1|UniProtKB=A0A2I2Y5Z8 A0A2I2Y5Z8 PTHR11364:SF6 THIOSULFATE SULFERTANSFERASE THIOSULFATE SULFURTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;transferase activity#GO:0016740;catalytic activity#GO:0003824 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA wobble position uridine thiolation#GO:0002143;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA thio-modification#GO:0034227;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000039233.1|UniProtKB=A0A2I2ZM37 A0A2I2ZM37 TBC1D25 PTHR22957:SF333 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 25 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 regulation of autophagosome maturation#GO:1901096;regulation of macroautophagy#GO:0016241;regulation of catabolic process#GO:0009894;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of protein-containing complex disassembly#GO:0043244;regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000038712.1|UniProtKB=A0A2I2Y7Z6 A0A2I2Y7Z6 KCTD4 PTHR14499:SF9 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027465.2|UniProtKB=G3S182 G3S182 EDRF1 PTHR15000:SF1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 GORGO|Gene=MAPT|UniProtKB=Q5YCW0 Q5YCW0 MAPT PTHR11501:SF14 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN TAU protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;microtubule binding#GO:0008017;binding#GO:0005488;molecular function regulator activity#GO:0098772;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;enzyme inhibitor activity#GO:0004857 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;regulation of microtubule-based process#GO:0032886;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;axon#GO:0030424;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000003170.3|UniProtKB=G3QKZ2 G3QKZ2 FRAS1 PTHR45739:SF1 MATRIX PROTEIN, PUTATIVE-RELATED EXTRACELLULAR MATRIX ORGANIZING PROTEIN FRAS1 anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;epithelial structure maintenance#GO:0010669;homeostatic process#GO:0042592;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001391.3|UniProtKB=G3QGC0 G3QGC0 LMAN2L PTHR12223:SF20 VESICULAR MANNOSE-BINDING LECTIN VIP36-LIKE PROTEIN monosaccharide binding#GO:0048029;carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015800.3|UniProtKB=G3RIB8 G3RIB8 MEFV PTHR24103:SF606 E3 UBIQUITIN-PROTEIN LIGASE TRIM PYRIN catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 immune response#GO:0006955;defense response to symbiont#GO:0140546;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000003086.3|UniProtKB=G3QKQ2 G3QKQ2 MED10 PTHR13345:SF13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000007584.3|UniProtKB=G3QX84 G3QX84 PHKG1 PTHR24347:SF386 SERINE/THREONINE-PROTEIN KINASE PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, SKELETAL MUSCLE_HEART ISOFORM protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;response to stimulus#GO:0050896;polysaccharide metabolic process#GO:0005976;regulation of cellular process#GO:0050794;signaling#GO:0023052;carbohydrate metabolic process#GO:0005975;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;energy reserve metabolic process#GO:0006112 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 GORGO|Ensembl=ENSGGOG00000015180.3|UniProtKB=G3RGQ4 G3RGQ4 MRTFA PTHR22793:SF6 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN-RELATED TRANSCRIPTION FACTOR A anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;muscle structure development#GO:0061061;cell differentiation#GO:0030154;cellular process#GO:0009987;muscle cell differentiation#GO:0042692 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000007887.3|UniProtKB=A0A2I2YU74 A0A2I2YU74 RAB40C PTHR47980:SF2 LD44762P RAS-RELATED PROTEIN RAB-40C enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 secretion#GO:0046903;protein metabolic process#GO:0019538;localization#GO:0051179;secretion by cell#GO:0032940;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;export from cell#GO:0140352;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;exocytosis#GO:0006887;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;transport#GO:0006810;vesicle-mediated transport#GO:0016192;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 GORGO|Ensembl=ENSGGOG00000008074.3|UniProtKB=A0A2I2ZFI5 A0A2I2ZFI5 DENND1B PTHR13196:SF24 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1B lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;binding#GO:0005488 positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;transport#GO:0006810;positive regulation of immune response#GO:0050778;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;localization#GO:0051179;localization within membrane#GO:0051668;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;activation of immune response#GO:0002253;signal transduction#GO:0007165;import into cell#GO:0098657;immune response-activating signaling pathway#GO:0002757;endosomal transport#GO:0016197;cell surface receptor signaling pathway#GO:0007166;endocytosis#GO:0006897;endocytic recycling#GO:0032456;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;cellular localization#GO:0051641;immune system process#GO:0002376 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000014332.3|UniProtKB=A0A2I2YPF0 A0A2I2YPF0 ERCC1 PTHR12749:SF0 EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1 DNA EXCISION REPAIR PROTEIN ERCC-1 DNA binding#GO:0003677;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular response to abiotic stimulus#GO:0071214;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;response to UV#GO:0009411;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;mitotic recombination#GO:0006312;cellular response to stress#GO:0033554;cellular response to environmental stimulus#GO:0104004;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 endodeoxyribonuclease#PC00093 GORGO|Ensembl=ENSGGOG00000002845.3|UniProtKB=G3QK32 G3QK32 MBLAC2 PTHR42951:SF4 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING ACYL-COENZYME A THIOESTERASE MBLAC2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000006895.3|UniProtKB=A0A2I2YRT6 A0A2I2YRT6 MTA3 PTHR10865:SF6 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA3 transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;histone deacetylase binding#GO:0042826;transcription coactivator activity#GO:0003713 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000012544.4|UniProtKB=G3R9Z8 G3R9Z8 TMTC4 PTHR44227:SF3 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC4 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;protein O-linked glycosylation via mannose#GO:0035269;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000041761.1|UniProtKB=A0A2I2YP99 A0A2I2YP99 IMPACT PTHR16301:SF25 IMPACT-RELATED PROTEIN IMPACT intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of translational initiation#GO:0006446;cellular response to stress#GO:0033554 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000010782.3|UniProtKB=G3R5E0 G3R5E0 GBP6 PTHR10751:SF117 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 6 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 heterotrimeric G-protein#PC00117;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000002661.3|UniProtKB=G3S1W5 G3S1W5 GBP3 PTHR10751:SF146 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 3 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 heterotrimeric G-protein#PC00117;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000013068.3|UniProtKB=A0A2I2YPW0 A0A2I2YPW0 DYRK1B PTHR24058:SF12 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1B transcription coactivator activity#GO:0003713;catalytic activity, acting on a protein#GO:0140096;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;transcription regulator activity#GO:0140110 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010520.3|UniProtKB=G3R4Q3 G3R4Q3 RUVBL1 PTHR11093:SF6 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 1 macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 ribonucleoprotein complex biogenesis#GO:0022613;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;protein-RNA complex assembly#GO:0022618;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;cellular component assembly#GO:0022607;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;protein-containing complex organization#GO:0043933;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of biosynthetic process#GO:0009889 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000010380.3|UniProtKB=G3R4C9 G3R4C9 DTX1 PTHR12622:SF7 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;cell communication#GO:0007154;biological regulation#GO:0065007;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;ubiquitin-dependent protein catabolic process#GO:0006511;neurogenesis#GO:0022008;Notch signaling pathway#GO:0007219;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;signal transduction#GO:0007165;gliogenesis#GO:0042063;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000015629.3|UniProtKB=G3RHX4 G3RHX4 TMEM260 PTHR16214:SF3 TRANSMEMBRANE PROTEIN 260 PROTEIN O-MANNOSYL-TRANSFERASE TMEM260 GORGO|Ensembl=ENSGGOG00000002508.3|UniProtKB=G3QJ89 G3QJ89 HPS1 PTHR12761:SF1 HERMANSKY-PUDLAK SYNDROME PROTEIN 1 BLOC-3 COMPLEX MEMBER HPS1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular pigmentation#GO:0033059;cellular component assembly#GO:0022607;melanosome organization#GO:0032438;pigmentation#GO:0043473;organelle assembly#GO:0070925;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000007532.3|UniProtKB=G3QX37 G3QX37 LOC101153729 PTHR31943:SF1 INTERLEUKIN-28 AND 29 INTERFERON LAMBDA-2-RELATED signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 defense response#GO:0006952;response to external stimulus#GO:0009605;response to virus#GO:0009615;innate immune response#GO:0045087;immune system process#GO:0002376;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to virus#GO:0051607 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000002310.3|UniProtKB=G3QIQ6 G3QIQ6 LOC101125081 PTHR11588:SF330 TUBULIN TUBULIN BETA-2B CHAIN purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 microtubule-based process#GO:0007017;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cellular process#GO:0009987;organelle organization#GO:0006996;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell motility#GO:0048870;mitotic cell cycle#GO:0000278;cell differentiation#GO:0030154;cellular component organization#GO:0016043;cell cycle#GO:0007049 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>beta-Tubulin#P00790 GORGO|Ensembl=ENSGGOG00000004469.3|UniProtKB=A0A2I2ZJY7 A0A2I2ZJY7 SPRED3 PTHR11202:SF19 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037876.1|UniProtKB=G3R7J2 G3R7J2 ATP5MK PTHR34038:SF1 ATP SYNTHASE MEMBRANE SUBUNIT DAPIT, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT K, MITOCHONDRIAL transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000007953.3|UniProtKB=G3QY58 G3QY58 CGN PTHR46349:SF4 CINGULIN-LIKE PROTEIN 1-RELATED CINGULIN microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cell-cell junction#GO:0005911 GORGO|Ensembl=ENSGGOG00000010825.3|UniProtKB=G3R5H7 G3R5H7 TSPAN4 PTHR19282:SF40 TETRASPANIN TETRASPANIN-4 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007624.3|UniProtKB=G3QXC0 G3QXC0 MTF1 PTHR19818:SF131 ZINC FINGER PROTEIN ZIC AND GLI METAL REGULATORY TRANSCRIPTION FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006925.3|UniProtKB=A0A2I2YBR0 A0A2I2YBR0 TXN PTHR10438:SF18 THIOREDOXIN THIOREDOXIN catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036 cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Hypoxia response via HIF activation#P00030>Thioredoxin#P00825;Oxidative stress response#P00046>TRX#P01122 GORGO|Ensembl=ENSGGOG00000028447.2|UniProtKB=G3S2R4 G3S2R4 APOA4 PTHR18976:SF1 APOLIPOPROTEIN APOLIPOPROTEIN A-IV enzyme regulator activity#GO:0030234;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;binding#GO:0005488;molecular function regulator activity#GO:0098772;cholesterol transfer activity#GO:0120020;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;transporter activity#GO:0005215;sterol transfer activity#GO:0120015 lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;secondary alcohol metabolic process#GO:1902652;organophosphate ester transport#GO:0015748;small molecule metabolic process#GO:0044281;cholesterol metabolic process#GO:0008203;transport#GO:0006810;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sterol transport#GO:0015918;establishment of localization#GO:0051234;sterol metabolic process#GO:0016125;cholesterol efflux#GO:0033344;cellular process#GO:0009987;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;steroid metabolic process#GO:0008202;lipid transport#GO:0006869 vesicle#GO:0031982;very-low-density lipoprotein particle#GO:0034361;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;lipoprotein particle#GO:1990777;protein-lipid complex#GO:0032994;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;high-density lipoprotein particle#GO:0034364;membrane-bounded organelle#GO:0043227;plasma lipoprotein particle#GO:0034358 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000002655.3|UniProtKB=G3QJL8 G3QJL8 ZNF841 PTHR24390:SF267 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 22 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000015657.4|UniProtKB=G3RHZ7 G3RHZ7 MUSK PTHR24416:SF317 TYROSINE-PROTEIN KINASE RECEPTOR MUSCLE, SKELETAL RECEPTOR TYROSINE-PROTEIN KINASE signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;Wnt-protein binding#GO:0017147;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013654.3|UniProtKB=G3RCT9 G3RCT9 GRIK5 PTHR18966:SF351 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 5 amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;carboxylic acid transmembrane transporter activity#GO:0046943;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537 presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;sodium channel complex#GO:0034706;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group I pathway#P00041>GluR5#P01054;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>KA#P01026;Ionotropic glutamate receptor pathway#P00037>KA5#P01000 GORGO|Ensembl=ENSGGOG00000036148.1|UniProtKB=A0A2I2YUR6 A0A2I2YUR6 LOC101148694 PTHR21245:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Q RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000011100.3|UniProtKB=G3R676 G3R676 LRR1 PTHR45752:SF153 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT PROTEIN 1 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010356.3|UniProtKB=G3R4A6 G3R4A6 LHFPL1 PTHR12489:SF15 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 1 PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004802.3|UniProtKB=G3QQ48 G3QQ48 CIB1 PTHR45791:SF3 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING PROTEIN 1 metal ion binding#GO:0046872;magnesium ion binding#GO:0000287;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 GORGO|Ensembl=ENSGGOG00000027197.2|UniProtKB=G3S2J7 G3S2J7 BMT2 PTHR21008:SF0 S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1-RELATED S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432;response to nutrient levels#GO:0031667;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 GORGO|Ensembl=ENSGGOG00000007860.4|UniProtKB=G3QXY5 G3QXY5 THADA PTHR14387:SF7 THADA/DEATH RECEPTOR INTERACTING PROTEIN TRNA (32-2'-O)-METHYLTRANSFERASE REGULATOR THADA molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 RNA metabolic process#GO:0016070;methylation#GO:0032259;calcium ion homeostasis#GO:0055074;RNA modification#GO:0009451;inorganic ion homeostasis#GO:0098771;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;tRNA modification#GO:0006400;intracellular monoatomic ion homeostasis#GO:0006873;tRNA processing#GO:0008033;intracellular calcium ion homeostasis#GO:0006874;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;gene expression#GO:0010467;RNA processing#GO:0006396;monoatomic ion homeostasis#GO:0050801;tRNA methylation#GO:0030488;cellular process#GO:0009987;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;homeostatic process#GO:0042592;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012075.3|UniProtKB=G3R8R1 G3R8R1 LOC101137790 PTHR10454:SF134 CASPASE INACTIVE CASPASE-12 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197 response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;inflammatory response#GO:0006954;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;defense response#GO:0006952;positive regulation of apoptotic process#GO:0043065;positive regulation of response to external stimulus#GO:0032103;positive regulation of defense response#GO:0031349;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of neuron apoptotic process#GO:0043525;positive regulation of inflammatory response#GO:0050729;regulation of response to stress#GO:0080134 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;canonical inflammasome complex#GO:0061702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000040245.1|UniProtKB=A0A2I2YEC1 A0A2I2YEC1 RCAN1 PTHR10300:SF4 CALCIPRESSIN CALCIPRESSIN-1 molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000012909.3|UniProtKB=A0A2I2YB37 A0A2I2YB37 DGKG PTHR11255:SF36 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE GAMMA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;neutral lipid metabolic process#GO:0006638;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000009985.3|UniProtKB=A0A2I2Z6Q2 A0A2I2Z6Q2 FAM170A PTHR33517:SF3 PROTEIN FAM170B-RELATED PROTEIN FAM170A sexual reproduction#GO:0019953;reproductive process#GO:0022414;fertilization#GO:0009566 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000043464.1|UniProtKB=A0A2I2YXW4 A0A2I2YXW4 PTHR10252:SF96 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED TRANSCRIPTION FACTOR CBF_NF-Y_ARCHAEAL HISTONE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000014395.3|UniProtKB=A0A2I2Z9I2 A0A2I2Z9I2 PPM1B PTHR47992:SF105 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1B hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009322.3|UniProtKB=G3R1N5 G3R1N5 THBS3 PTHR10199:SF89 THROMBOSPONDIN THROMBOSPONDIN-3 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000043141.1|UniProtKB=A0A2I2YJN4 A0A2I2YJN4 LOC101124371 PTHR24031:SF645 RNA HELICASE ATP-DEPENDENT RNA HELICASE macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasmic stress granule#GO:0010494;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000008398.3|UniProtKB=A0A2I2Z5N8 A0A2I2Z5N8 PTHR10257:SF92 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT EPSILON ISOFORM phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;EGF receptor signaling pathway#P00018>PP2A#P00547 GORGO|Ensembl=ENSGGOG00000007253.3|UniProtKB=G3QWG4 G3QWG4 PTHR12295:SF29 FURRY-RELATED PROTEIN FURRY HOMOLOG anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987 cell division site#GO:0032153;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015007.3|UniProtKB=A0A2I2YKX7 A0A2I2YKX7 R3HDM2 PTHR15672:SF13 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN R3H DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000009812.3|UniProtKB=G3R2X8 G3R2X8 APLP2 PTHR23103:SF14 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID BETA PRECURSOR LIKE PROTEIN 2 axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;central nervous system development#GO:0007417;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;cellular process#GO:0009987;axon development#GO:0061564;neuron projection development#GO:0031175 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000001462.4|UniProtKB=G3QGJ0 G3QGJ0 PTHR24023:SF917 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000012041.3|UniProtKB=G3R8N9 G3R8N9 SPEN PTHR23189:SF48 RNA RECOGNITION MOTIF-CONTAINING MSX2-INTERACTING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006223.3|UniProtKB=G3QTR5 G3QTR5 CAMK2G PTHR24347:SF398 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT GAMMA transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of signaling#GO:0023051;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of neuronal synaptic plasticity#GO:0048168;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;regulation of synaptic plasticity#GO:0048167;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of neuron projection development#GO:0010975;regulation of protein localization to membrane#GO:1905475 postsynapse#GO:0098794;neuron projection#GO:0043005;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;postsynaptic density#GO:0014069;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 GORGO|Ensembl=ENSGGOG00000010718.3|UniProtKB=G3R579 G3R579 CIB4 PTHR45791:SF4 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 4 metal ion binding#GO:0046872;cation binding#GO:0043169;magnesium ion binding#GO:0000287;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 GORGO|Ensembl=ENSGGOG00000009294.3|UniProtKB=A0A2I2ZGW0 A0A2I2ZGW0 ACACB PTHR45728:SF1 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE 2 ligase activity#GO:0016874;catalytic activity#GO:0003824 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011869.3|UniProtKB=G3S6H4 G3S6H4 ITGB5 PTHR10082:SF26 INTEGRIN BETA SUBUNIT INTEGRIN BETA-5 protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839 stress fiber assembly#GO:0043149;cellular response to growth factor stimulus#GO:0071363;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;actomyosin structure organization#GO:0031032;response to endogenous stimulus#GO:0009719;integrin-mediated signaling pathway#GO:0007229;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;actin filament bundle organization#GO:0061572;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;cellular component assembly#GO:0022607;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;transforming growth factor beta receptor signaling pathway#GO:0007179;organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;enzyme-linked receptor protein signaling pathway#GO:0007167;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;response to transforming growth factor beta#GO:0071559;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;actin filament bundle assembly#GO:0051017;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;actin filament organization#GO:0007015;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell adhesion mediated by integrin#GO:0033627;contractile actin filament bundle assembly#GO:0030038;cell migration#GO:0016477;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;integrin complex#GO:0008305;cell junction#GO:0030054;anchoring junction#GO:0070161;signaling receptor complex#GO:0043235 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 GORGO|Ensembl=ENSGGOG00000013474.3|UniProtKB=G3RCC0 G3RCC0 GDI1 PTHR11787:SF3 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR ALPHA molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000016977.3|UniProtKB=G3RLC6 G3RLC6 SAXO4 PTHR34349:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 32 STABILIZER OF AXONEMAL MICROTUBULES 4 enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;protein binding#GO:0005515 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000022182.2|UniProtKB=G3RT53 G3RT53 EPOR PTHR23037:SF28 CYTOKINE RECEPTOR ERYTHROPOIETIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016693.2|UniProtKB=Q8MHW5 Q8MHW5 GJB2 PTHR11984:SF46 CONNEXIN GAP JUNCTION BETA-2 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 ear development#GO:0043583;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell junction organization#GO:0034330;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;establishment of localization#GO:0051234;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;transport#GO:0006810;sensory organ development#GO:0007423;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;inner ear development#GO:0048839 cell junction#GO:0030054;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 gap junction#PC00105;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000011825.3|UniProtKB=A0A2I2YXQ8 A0A2I2YXQ8 PTGFRN PTHR12207:SF3 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN PROSTAGLANDIN F2 RECEPTOR NEGATIVE REGULATOR cellular anatomical structure#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000042543.1|UniProtKB=A0A2I2ZNH9 A0A2I2ZNH9 PTHR10288:SF327 KH DOMAIN CONTAINING RNA BINDING PROTEIN K HOMOLOGY DOMAIN-CONTAINING PROTEIN mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA splicing#GO:0043484;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000027947.2|UniProtKB=G3S8H2 G3S8H2 LAMTOR4 PTHR33967:SF1 RAGULATOR COMPLEX PROTEIN LAMTOR4 RAGULATOR COMPLEX PROTEIN LAMTOR4 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009123.4|UniProtKB=A0A2I2Y7C3 A0A2I2Y7C3 BCAS3 PTHR13268:SF0 BREAST CARCINOMA AMPLIFIED SEQUENCE 3 BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;metabolic process#GO:0008152;response to stimulus#GO:0050896;catabolic process#GO:0009056;macroautophagy#GO:0016236;response to starvation#GO:0042594;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;response to stress#GO:0006950;cellular component organization#GO:0016043;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407 non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000007218.3|UniProtKB=A0A2I2YS53 A0A2I2YS53 PTPN5 PTHR46198:SF1 PROTEIN-TYROSINE-PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 5 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000037112.1|UniProtKB=A0A2I2ZN43 A0A2I2ZN43 RFK PTHR22749:SF14 RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE RIBOFLAVIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;flavin-containing compound metabolic process#GO:0042726;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 Flavin biosynthesis#P02741>FAD synthetase#P02936;Flavin biosynthesis#P02741>Riboflavin kinase#P02934 GORGO|Ensembl=ENSGGOG00000017025.3|UniProtKB=A0A2I2Z2J5 A0A2I2Z2J5 ERMARD PTHR31701:SF2 ENDOPLASMIC RETICULUM MEMBRANE-ASSOCIATED RNA DEGRADATION PROTEIN ENDOPLASMIC RETICULUM MEMBRANE-ASSOCIATED RNA DEGRADATION PROTEIN multicellular organismal process#GO:0032501;cell migration#GO:0016477;cell motility#GO:0048870;cell differentiation#GO:0030154;nervous system development#GO:0007399;cellular process#GO:0009987;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;generation of neurons#GO:0048699 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000025559.2|UniProtKB=G3SCI1 G3SCI1 SCN9A PTHR10037:SF221 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 9 SUBUNIT ALPHA passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transmission of nerve impulse#GO:0019226;system process#GO:0003008;transport#GO:0006810;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;nervous system process#GO:0050877;sensory perception#GO:0007600;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;sensory perception of pain#GO:0019233;sodium ion transport#GO:0006814;action potential#GO:0001508 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000010090.3|UniProtKB=G3R3L7 G3R3L7 ZEB1 PTHR24391:SF17 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER E-BOX-BINDING HOMEOBOX 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#G06670;Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#G06884;Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#P06783 GORGO|Ensembl=ENSGGOG00000013632.3|UniProtKB=G3RCR9 G3RCR9 SH2D2A PTHR14388:SF9 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 2A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;cell activation#GO:0001775;immune system process#GO:0002376;leukocyte activation#GO:0045321;T cell activation#GO:0042110;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 defense/immunity protein#PC00090 VEGF signaling pathway#P00056>VRAP#P01405;Angiogenesis#P00005>VRAP#P00196 GORGO|Ensembl=ENSGGOG00000041416.1|UniProtKB=A0A2I2Y839 A0A2I2Y839 PTHR12682:SF12 ARCHEASE TRNA-SPLICING LIGASE-ACTIVATING FACTOR ARCHEASE intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000041036.1|UniProtKB=A0A2I2YVD8 A0A2I2YVD8 CCDC65 PTHR21625:SF0 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX SUBUNIT 2 cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cell projection organization#GO:0030030;regulation of microtubule-based movement#GO:0060632;cell motility#GO:0048870;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;cilium or flagellum-dependent cell motility#GO:0001539;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017 organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000016586.4|UniProtKB=A0A2I2ZQ81 A0A2I2ZQ81 ATP9A PTHR24092:SF49 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IIA-RELATED molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;intramembrane lipid carrier activity#GO:0140303 regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;endocytosis#GO:0006897;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;transport#GO:0006810;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;vesicle-mediated transport#GO:0016192;lipid transport#GO:0006869;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;macromolecule localization#GO:0033036 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006217.3|UniProtKB=G3QTQ6 G3QTQ6 UTP25 PTHR12933:SF0 ORF PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;binding#GO:0005488 RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009380.3|UniProtKB=G3R1T6 G3R1T6 PTHR47091:SF1 ALPHA-PROTEIN KINASE 2-RELATED ALPHA-PROTEIN KINASE 3 circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061;cell development#GO:0048468;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;heart development#GO:0007507;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cardiac muscle cell differentiation#GO:0055007;cellular process#GO:0009987;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;animal organ development#GO:0048513;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146;striated muscle tissue development#GO:0014706;developmental process#GO:0032502 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000009453.3|UniProtKB=G3R1Z9 G3R1Z9 BCLAF3 PTHR15268:SF17 THRAP3/BCLAF1 BCLAF1 AND THRAP3 FAMILY MEMBER 3 DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000012031.3|UniProtKB=G3R8N1 G3R8N1 DDX56 PTHR24031:SF781 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX56-RELATED cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to virus#GO:0051607;defense response#GO:0006952;response to external stimulus#GO:0009605;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;response to other organism#GO:0051707;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;rRNA processing#GO:0006364;response to virus#GO:0009615;RNA biosynthetic process#GO:0032774;response to external biotic stimulus#GO:0043207;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000001844.3|UniProtKB=G3QHI8 G3QHI8 MED29 PTHR28314:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000005207.3|UniProtKB=G3QR68 G3QR68 FAM120B PTHR15976:SF17 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular receptor signaling pathway#GO:0030522;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000006886.3|UniProtKB=A0A2I2YJ23 A0A2I2YJ23 NOX1 PTHR11972:SF71 NADPH OXIDASE NADPH OXIDASE 1 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 metabolic process#GO:0008152;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987;response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801;defense response#GO:0006952 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000002063.3|UniProtKB=G3QI33 G3QI33 TP53RK PTHR12209:SF0 NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE EKC_KEOPS COMPLEX SUBUNIT TP53RK phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011303.3|UniProtKB=G3R6Q4 G3R6Q4 PBX1 PTHR11850:SF89 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron development#GO:0048666;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell development#GO:0048468;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;positive regulation of macromolecule metabolic process#GO:0010604;head development#GO:0060322;nervous system development#GO:0007399;embryo development#GO:0009790;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;embryonic organ development#GO:0048568;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;sensory organ development#GO:0007423;developmental process#GO:0032502;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 Gonadotropin-releasing hormone receptor pathway#P06664>Pbx1#P06729 GORGO|Ensembl=ENSGGOG00000015338.3|UniProtKB=G3RH48 G3RH48 PTX3 PTHR46943:SF1 PENTRAXIN-RELATED PROTEIN PTX3 PENTRAXIN-RELATED PROTEIN PTX3 complement binding#GO:0001848;binding#GO:0005488;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000008879.3|UniProtKB=A0A2I2Y805 A0A2I2Y805 MYOCD PTHR22793:SF11 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN cellular process#GO:0009987;cardiac muscle cell differentiation#GO:0055007;heart development#GO:0007507;tissue development#GO:0009888;multicellular organismal process#GO:0032501;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;striated muscle cell differentiation#GO:0051146;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;animal organ development#GO:0048513;muscle cell differentiation#GO:0042692;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061;animal gross anatomical part developmental process#GO:0160108;muscle tissue development#GO:0060537;system development#GO:0048731;anatomical structure development#GO:0048856 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000036878.1|UniProtKB=A0A2I2ZLA1 A0A2I2ZLA1 PTHR46512:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP8 protein maturation#GO:0051604;gene expression#GO:0010467;positive regulation of response to stimulus#GO:0048584;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;macromolecule metabolic process#GO:0043170;positive regulation of BMP signaling pathway#GO:0030513;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;protein folding#GO:0006457;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;cytosol#GO:0005829;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000001193.3|UniProtKB=G3QFU6 G3QFU6 PTHR47979:SF17 DRAB11-RELATED RAS-RELATED PROTEIN RAB-4B purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924 regulation of transport#GO:0051049;regulation of localization#GO:0032879;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;regulation of endocytosis#GO:0030100;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of biological process#GO:0050789 recycling endosome#GO:0055037;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000013005.3|UniProtKB=A0A2I2ZMY5 A0A2I2ZMY5 SBF1 PTHR10807:SF43 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 5 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;phosphoric ester hydrolase activity#GO:0042578;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;dephosphorylation#GO:0016311;lipid modification#GO:0030258;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000009961.3|UniProtKB=G3SAY1 G3SAY1 ARMCX5 PTHR47081:SF2 FAMILY NOT NAMED ARMADILLO REPEAT-CONTAINING X-LINKED PROTEIN 5 GORGO|Ensembl=ENSGGOG00000037243.1|UniProtKB=A0A2I2ZP80 A0A2I2ZP80 CHAMP1 PTHR37354:SF1 CHROMOSOME ALIGNMENT-MAINTAINING PHOSPHOPROTEIN 1 CHROMOSOME ALIGNMENT-MAINTAINING PHOSPHOPROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle localization#GO:0051640;nuclear division#GO:0000280;sister chromatid biorientation#GO:0031134;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;organelle fission#GO:0048285;localization#GO:0051179;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic metaphase chromosome alignment#GO:0007080;mitotic cell cycle#GO:0000278;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;chromosome localization#GO:0050000 organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;membraneless organelle#GO:0043228;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000016833.3|UniProtKB=A0A2I2ZSB9 A0A2I2ZSB9 SCN3A PTHR10037:SF237 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 3 SUBUNIT ALPHA monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 transport#GO:0006810;transmission of nerve impulse#GO:0019226;system process#GO:0003008;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;sodium ion transport#GO:0006814;action potential#GO:0001508;sensory perception of pain#GO:0019233;membrane depolarization#GO:0051899;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;axon#GO:0030424;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;transporter complex#GO:1990351;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000034884.2|UniProtKB=G3SKE6 G3SKE6 PLEKHS1 PTHR47014:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY S MEMBER 1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY S MEMBER 1 GORGO|Ensembl=ENSGGOG00000026258.2|UniProtKB=G3SIN4 G3SIN4 SCGB1D2 PTHR11332:SF6 SECRETOGLOBIN FAMILY 1D SECRETOGLOBIN FAMILY 1D MEMBER 2 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000037271.1|UniProtKB=A0A2I2ZPT3 A0A2I2ZPT3 LOC101128917 PTHR19431:SF5 60S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001605.3|UniProtKB=A0A2I2ZWN4 A0A2I2ZWN4 ARHGAP36 PTHR12635:SF8 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE-ACTIVATING PROTEIN 36 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000006442.3|UniProtKB=G3QUA3 G3QUA3 KCNAB3 PTHR43150:SF3 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-3 catalytic activity#GO:0003824;ion channel regulator activity#GO:0099106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;molecular function regulator activity#GO:0098772;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;potassium channel regulator activity#GO:0015459;binding#GO:0005488;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;channel regulator activity#GO:0016247;protein binding#GO:0005515;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;biological regulation#GO:0065007;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 GORGO|Ensembl=ENSGGOG00000034982.2|UniProtKB=G3SKG2 G3SKG2 ARHGAP15 PTHR23176:SF108 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 15 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000014423.3|UniProtKB=G3RES6 G3RES6 EDNRB PTHR46099:SF3 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN RECEPTOR TYPE B peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;pigmentation#GO:0043473;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;developmental pigmentation#GO:0048066;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>ET-RA/B#P00580 GORGO|Ensembl=ENSGGOG00000003311.3|UniProtKB=A0A2I2Y663 A0A2I2Y663 PTHR43655:SF9 ATP-DEPENDENT PROTEASE MITOCHONDRIAL INNER MEMBRANE M-AAA PROTEASE COMPONENT AFG3L2 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000006202.3|UniProtKB=G3QTN6 G3QTN6 OGN PTHR46269:SF1 EPIPHYCAN-RELATED MIMECAN tissue development#GO:0009888;multicellular organismal process#GO:0032501;bone development#GO:0060348;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;system development#GO:0048731;connective tissue development#GO:0061448;cartilage development#GO:0051216;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004563.3|UniProtKB=G3RVX3 G3RVX3 KDM5A PTHR10694:SF17 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5A histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000012852.3|UniProtKB=G3RAS1 G3RAS1 ITGA2B PTHR23220:SF73 INTEGRIN ALPHA INTEGRIN ALPHA-IIB molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 animal gross anatomical part developmental process#GO:0160108;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007 plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 integrin#PC00126;cell adhesion molecule#PC00069 Blood coagulation#P00011>GP IIb#P00410;Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000005464.3|UniProtKB=A0A2I2YNV3 A0A2I2YNV3 ECSIT PTHR13113:SF1 ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY, MITOCHONDRIAL regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;toll-like receptor 4 signaling pathway#GO:0034142;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>ECSIT#P01349 GORGO|Ensembl=ENSGGOG00000043072.1|UniProtKB=G3RJL4 G3RJL4 LOC101153126 PTHR24377:SF739 IP01015P-RELATED ZINC FINGER PROTEIN 728 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009344.3|UniProtKB=A0A2I2YJV8 A0A2I2YJV8 PTHR11069:SF34 GLUCOSYLCERAMIDASE GLUCOSYLCERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;ceramide metabolic process#GO:0006672;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629 GORGO|Ensembl=ENSGGOG00000010173.3|UniProtKB=A0A2I2YEB7 A0A2I2YEB7 ZNF180 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005489.3|UniProtKB=G3QRV7 G3QRV7 URAD PTHR43466:SF2 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000037774.1|UniProtKB=A0A2I2YTD8 A0A2I2YTD8 PTHR31943:SF18 INTERLEUKIN-28 AND 29 INTERFERON LAMBDA 4 receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 innate immune response#GO:0045087;response to virus#GO:0009615;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to virus#GO:0051607;immune response#GO:0006955;defense response to symbiont#GO:0140546 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;cytokine#PC00083;interleukin superfamily#PC00128 GORGO|Ensembl=ENSGGOG00000016299.3|UniProtKB=G3RJL2 G3RJL2 TM7SF3 PTHR15937:SF3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000001309.3|UniProtKB=G3RXE6 G3RXE6 SYAP1 PTHR16019:SF6 SYNAPSE-ASSOCIATED PROTEIN SYNAPSE-ASSOCIATED PROTEIN 1 positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;TOR signaling#GO:0031929;biological regulation#GO:0065007;positive regulation of fat cell differentiation#GO:0045600;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;TORC2 signaling#GO:0038203;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;synapse#GO:0045202;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000028020.2|UniProtKB=G3S680 G3S680 PTHR23105:SF186 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010780.3|UniProtKB=G3R5D8 G3R5D8 GADD45A PTHR10411:SF3 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 ALPHA molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 p53 pathway#P00059>GADD45#G01575;PI3 kinase pathway#P00048>GADD45#G01544;p38 MAPK pathway#P05918>GADD45#P06044;p53 pathway#P00059>GADD45#P04626 GORGO|Ensembl=ENSGGOG00000039549.1|UniProtKB=A0A2I2YRD4 A0A2I2YRD4 PCP4L1 PTHR15359:SF5 IG-LIKE DOMAIN-CONTAINING PROTEIN PURKINJE CELL PROTEIN 4-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000002978.3|UniProtKB=G3QKF3 G3QKF3 FST PTHR10913:SF6 FOLLISTATIN-RELATED FOLLISTATIN activin binding#GO:0048185;binding#GO:0005488;protein-containing complex binding#GO:0044877 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#G06671;Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#P06835;Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#G06885 GORGO|Ensembl=ENSGGOG00000027408.2|UniProtKB=G3QMA4 G3QMA4 RAB43 PTHR47978:SF64 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-37 GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endosome#GO:0005768;intracellular organelle#GO:0043229 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000002973.3|UniProtKB=G3QKF9 G3QKF9 COL4A6 PTHR24023:SF533 COLLAGEN ALPHA COLLAGEN ALPHA-6(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000014442.3|UniProtKB=G3REU2 G3REU2 LOC101132879 PTHR23105:SF189 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN EL8 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000013630.3|UniProtKB=G3RCR2 G3RCR2 LOC101141025 PTHR19944:SF46 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DP BETA 1 CHAIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823;protein-containing complex binding#GO:0044877 positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of cellular process#GO:0048522;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of leukocyte activation#GO:0002696;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;vesicle#GO:0031982;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;late endosome membrane#GO:0031902 major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000012475.4|UniProtKB=G3R9S5 G3R9S5 MARCHF1 PTHR45981:SF1 LD02310P E3 UBIQUITIN-PROTEIN LIGASE MARCHF1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;MHC protein binding#GO:0042287;binding#GO:0005488;signaling receptor binding#GO:0005102;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515 cellular process#GO:0009987;immune response#GO:0006955;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;response to stimulus#GO:0050896;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376;protein metabolic process#GO:0019538;antigen processing and presentation#GO:0019882;macromolecule modification#GO:0043412 early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;early endosome membrane#GO:0031901;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000008107.3|UniProtKB=G3QYI6 G3QYI6 KLHL28 PTHR24412:SF441 KELCH PROTEIN KELCH-LIKE PROTEIN 28 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010009.3|UniProtKB=G3R3E3 G3R3E3 SRPX2 PTHR46343:SF3 HYR DOMAIN-CONTAINING PROTEIN SUSHI REPEAT-CONTAINING PROTEIN SRPX2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell motility#GO:2000145;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;regulation of biological quality#GO:0065008;cell adhesion#GO:0007155;positive regulation of cellular component organization#GO:0051130;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;positive regulation of synapse assembly#GO:0051965;positive regulation of locomotion#GO:0040017;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;regulation of synapse assembly#GO:0051963;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of multicellular organismal process#GO:0051239;cell-cell adhesion#GO:0098609;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000012189.3|UniProtKB=G3R924 G3R924 TFB1M PTHR11727:SF17 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;transcription regulator activity#GO:0140110 cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;DNA-templated transcription initiation#GO:0006352;rRNA modification#GO:0000154;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;mitochondrial transcription#GO:0006390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;mitochondrial gene expression#GO:0140053;rRNA processing#GO:0006364;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000000982.3|UniProtKB=G3QFA4 G3QFA4 ENPP3 PTHR10151:SF107 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 3 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429 regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;phosphorus metabolic process#GO:0006793;regulation of cell communication#GO:0010646;nucleoside triphosphate metabolic process#GO:0009141;regulation of response to biotic stimulus#GO:0002831;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of innate immune response#GO:0045088;cellular process#GO:0009987;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000037515.1|UniProtKB=G3QCW7 G3QCW7 LOC101140821 PTHR26450:SF353 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52L2-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001203.3|UniProtKB=G3QFV4 G3QFV4 DHDH PTHR22604:SF105 OXIDOREDUCTASES TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000042724.1|UniProtKB=A0A2I2Z5K7 A0A2I2Z5K7 PTHR31978:SF3 INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;localization#GO:0051179;organelle assembly#GO:0070925 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;ciliary base#GO:0097546;neuron projection#GO:0043005 GORGO|Ensembl=ENSGGOG00000004940.3|UniProtKB=G3QQH6 G3QQH6 GGCX PTHR12639:SF6 VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831 ketone metabolic process#GO:0042180;vitamin K metabolic process#GO:0042373;metabolic process#GO:0008152;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000016648.3|UniProtKB=G3RKH6 G3RKH6 FN3KRP PTHR12149:SF10 FRUCTOSAMINE 3 KINASE-RELATED PROTEIN KETOSAMINE-3-KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein repair#GO:0030091;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000041759.1|UniProtKB=A0A2I2ZJY6 A0A2I2ZJY6 PTHR10218:SF315 GTP-BINDING PROTEIN ALPHA SUBUNIT GNA11 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of membrane potential#GO:0042391;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;action potential#GO:0001508;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562 G-protein#PC00020;heterotrimeric G-protein#PC00117 GORGO|Ensembl=ENSGGOG00000014517.3|UniProtKB=G3SAL5 G3SAL5 SLC25A16 PTHR24089:SF705 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A16 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000039766.1|UniProtKB=A0A2I2YXV6 A0A2I2YXV6 PTHR45942:SF3 Calcineurin subunit B CALCINEURIN SUBUNIT B TYPE 1 enzyme regulator activity#GO:0030234;protein binding#GO:0005515;protein phosphatase regulator activity#GO:0019888;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;calcineurin-mediated signaling#GO:0097720;calcineurin-NFAT signaling cascade#GO:0033173;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 Wnt signaling pathway#P00057>Calcineurin#P01446 GORGO|Gene=ASIP|UniProtKB=Q1XGV5 Q1XGV5 ASIP PTHR16551:SF1 AGOUTI RELATED AGOUTI-SIGNALING PROTEIN signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;neuropeptide hormone activity#GO:0005184;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000008143.3|UniProtKB=G3QYL5 G3QYL5 PTHR11588:SF429 TUBULIN TUBULIN BETA 8B-RELATED guanyl nucleotide binding#GO:0019001;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 GORGO|Ensembl=ENSGGOG00000010948.3|UniProtKB=G3R5T8 G3R5T8 DNAAF8 PTHR35977:SF1 CHROMOSOME 16 OPEN READING FRAME 71 DYNEIN AXONEMAL ASSEMBLY FACTOR 8 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000013387.3|UniProtKB=G3RC35 G3RC35 LAMP5 PTHR11506:SF45 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 5 establishment of protein localization#GO:0045184;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of localization#GO:0051234 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;late endosome membrane#GO:0031902;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000003481.3|UniProtKB=G3RY90 G3RY90 JPH3 PTHR23085:SF7 GH28348P JUNCTOPHILIN-3 regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000015891.3|UniProtKB=G3RIJ4 G3RIJ4 TRIM27 PTHR24103:SF362 E3 UBIQUITIN-PROTEIN LIGASE TRIM ZINC FINGER PROTEIN RFP ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;immune response#GO:0006955;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;immune system process#GO:0002376;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;negative regulation of macromolecule biosynthetic process#GO:0010558;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000040338.1|UniProtKB=A0A2I2ZV03 A0A2I2ZV03 TMEM167B PTHR46815:SF1 PROTEIN KISH-B PROTEIN KISH-B GORGO|Ensembl=ENSGGOG00000005778.3|UniProtKB=G3SI68 G3SI68 DPP4 PTHR11731:SF128 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 4 catalytic activity#GO:0003824;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000016581.3|UniProtKB=G3RKA9 G3RKA9 CST5 PTHR46186:SF1 CYSTATIN CYSTATIN-D cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000037304.1|UniProtKB=A0A2I2YDN3 A0A2I2YDN3 TRH PTHR17530:SF2 PRO-THYROTROPIN-RELEASING HORMONE PRO-THYROTROPIN-RELEASING HORMONE signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585 GORGO|Ensembl=ENSGGOG00000022055.2|UniProtKB=G3SBD8 G3SBD8 LOC101130073 PTHR26452:SF806 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A16 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000011121.3|UniProtKB=G3R6A0 G3R6A0 STX18 PTHR15959:SF1 SYNTAXIN-18 SYNTAXIN-18 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;SNARE protein#PC00034 GORGO|Ensembl=ENSGGOG00000034930.2|UniProtKB=A0A2I2YW59 A0A2I2YW59 NME9 PTHR46135:SF1 NME/NM23 FAMILY MEMBER 8 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 6 GORGO|Ensembl=ENSGGOG00000014981.3|UniProtKB=A0A2I2YF26 A0A2I2YF26 ZC2HC1A PTHR13555:SF25 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1A C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000037132.1|UniProtKB=A0A2I2ZPQ6 A0A2I2ZPQ6 SFRP1 PTHR11309:SF87 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 1 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023 non-canonical Wnt signaling pathway#GO:0035567;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434;Angiogenesis#P00005>FRP#P00237 GORGO|Ensembl=ENSGGOG00000002212.3|UniProtKB=G3QIH2 G3QIH2 FAM83B PTHR16181:SF31 PROTEIN FAM83A-RELATED PROTEIN FAM83B kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000002380.3|UniProtKB=G3QIX1 G3QIX1 GPR150 PTHR24241:SF83 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 150-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003817.3|UniProtKB=G3QMK7 G3QMK7 PTHR24243:SF3 G-PROTEIN COUPLED RECEPTOR MOTILIN RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000040388.1|UniProtKB=G3RKL7 G3RKL7 LOC101133676 PTHR26453:SF63 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2F2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008599.3|UniProtKB=G3QZU5 G3QZU5 PFAS PTHR10099:SF1 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 De novo purine biosynthesis#P02738>Phosphoribosylformylglycinamide synthase#P02898 GORGO|Ensembl=ENSGGOG00000036721.1|UniProtKB=A0A2I2ZQH0 A0A2I2ZQH0 PTHR19343:SF3 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 12-2 antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010428.3|UniProtKB=A0A2I2YX16 A0A2I2YX16 ENTPD4 PTHR11782:SF29 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 4 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462 ribonucleoside diphosphate catabolic process#GO:0009191;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;ribonucleotide metabolic process#GO:0009259;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;ribonucleoside diphosphate metabolic process#GO:0009185;nucleoside diphosphate catabolic process#GO:0009134;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121;nucleotide phosphatase#PC00173 GORGO|Ensembl=ENSGGOG00000034819.2|UniProtKB=G3SKF4 G3SKF4 CCDC57 PTHR46725:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 57 COILED-COIL DOMAIN-CONTAINING PROTEIN 57 biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;microtubule polymerization or depolymerization#GO:0031109;microtubule polymerization#GO:0046785;positive regulation of mitotic cell cycle#GO:0045931;plasma membrane bounded cell projection assembly#GO:0120031;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;positive regulation of cell cycle#GO:0045787;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;regulation of cell cycle#GO:0051726;cell projection organization#GO:0030030;centrosome cycle#GO:0007098;regulation of biological process#GO:0050789;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;microtubule nucleation#GO:0007020;cilium assembly#GO:0060271;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cilium organization#GO:0044782 spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriolar satellite#GO:0034451;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000014727.3|UniProtKB=G3RFJ8 G3RFJ8 RAX2 PTHR46271:SF2 HOMEOBOX PROTEIN, PUTATIVE-RELATED RETINA AND ANTERIOR NEURAL FOLD HOMEOBOX PROTEIN 2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000010876.3|UniProtKB=A0A2I2YDR0 A0A2I2YDR0 RHBDL3 PTHR45840:SF5 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 3 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 GORGO|Ensembl=ENSGGOG00000040228.1|UniProtKB=A0A2I2Y341 A0A2I2Y341 MLLT11 PTHR15404:SF2 PROTEIN AF1Q PROTEIN AF1Q regulation of biosynthetic process#GO:0009889;regulation of membrane potential#GO:0042391;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of release of cytochrome c from mitochondria#GO:0090199;positive regulation of cellular component organization#GO:0051130;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of organelle organization#GO:0010638;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000005494.3|UniProtKB=G3QRW5 G3QRW5 NEU2 PTHR10628:SF6 SIALIDASE SIALIDASE-2 catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;ceramide metabolic process#GO:0006672;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;glycolipid metabolic process#GO:0006664;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane#GO:0016020 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000014129.3|UniProtKB=G3RE16 G3RE16 CMBL PTHR46812:SF1 CARBOXYMETHYLENEBUTENOLIDASE HOMOLOG CARBOXYMETHYLENEBUTENOLIDASE HOMOLOG GORGO|Ensembl=ENSGGOG00000042971.1|UniProtKB=A0A2I2ZWU8 A0A2I2ZWU8 ZNF432 PTHR24381:SF479 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 432 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000038033.1|UniProtKB=A0A2I2YAY9 A0A2I2YAY9 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000005952.3|UniProtKB=A0A2I2YQ75 A0A2I2YQ75 COG4 PTHR24016:SF21 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;retrograde transport, vesicle recycling within Golgi#GO:0000301;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 COG complex#GO:0017119;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000001212.3|UniProtKB=G3QFW3 G3QFW3 SLC28A3 PTHR10590:SF26 SODIUM/NUCLEOSIDE COTRANSPORTER SOLUTE CARRIER FAMILY 28 MEMBER 3 nucleobase-containing compound transmembrane transporter activity#GO:0015932;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate derivative transmembrane transporter activity#GO:1901505;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;nucleoside transmembrane transporter activity#GO:0005337;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;nucleobase transmembrane transporter activity#GO:0015205;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024650.2|UniProtKB=G3S293 G3S293 PTCHD4 PTHR10796:SF15 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 4 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000040282.1|UniProtKB=A0A2I2ZD47 A0A2I2ZD47 PTHR11913:SF82 COFILIN-RELATED ADF-H DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;actin cytoskeleton organization#GO:0030036;actin filament depolymerization#GO:0030042;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000010535.3|UniProtKB=G3S5N7 G3S5N7 NLK PTHR24055:SF380 MITOGEN-ACTIVATED PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NLK catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Nemo-like Kinase#P01449 GORGO|Ensembl=ENSGGOG00000002652.3|UniProtKB=A0A2I2ZR08 A0A2I2ZR08 LOC101131142 PTHR11502:SF34 40S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN ES6 ribosomal protein#PC00202 CCKR signaling map#P06959>RPS6#P07143 GORGO|Ensembl=ENSGGOG00000004461.3|UniProtKB=A0A2I2YW77 A0A2I2YW77 SS18 PTHR23107:SF2 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN PROTEIN SSXT transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000005981.3|UniProtKB=G3QT52 G3QT52 CLSPN PTHR14396:SF10 CLASPIN CLASPIN GORGO|Ensembl=ENSGGOG00000026945.2|UniProtKB=G3S8T5 G3S8T5 PTHR48112:SF6 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B3 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000006869.3|UniProtKB=G3QVF3 G3QVF3 ZNF221 PTHR24381:SF428 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 234 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000009176.3|UniProtKB=A0A2I2ZVL6 A0A2I2ZVL6 LOC101149175 PTHR20854:SF26 INOSITOL MONOPHOSPHATASE INOSITOL MONOPHOSPHATASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000037208.1|UniProtKB=A0A2I2ZY81 A0A2I2ZY81 PTHR14499:SF128 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL TETRAMERIZATION DOMAIN CONTAINING 21 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;presynaptic active zone#GO:0048786;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;presynaptic active zone membrane#GO:0048787;postsynaptic membrane#GO:0045211 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011686.3|UniProtKB=G3RV64 G3RV64 ANAPC2 PTHR45957:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 metaphase/anaphase transition of cell cycle#GO:0044784;regulation of chromosome segregation#GO:0051983;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;protein modification by small protein conjugation or removal#GO:0070647;mitotic cell cycle phase transition#GO:0044772;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;protein K11-linked ubiquitination#GO:0070979;cell cycle#GO:0007049;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;mitotic cell cycle#GO:0000278;regulation of cellular component organization#GO:0051128;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680 Cell cycle#P00013>APC#P00481 GORGO|Ensembl=ENSGGOG00000011324.3|UniProtKB=A0A2I2Z2B5 A0A2I2Z2B5 DDAH2 PTHR12737:SF16 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE HYDROLASE DDAH2-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule metabolic process#GO:0044281;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;oxoacid metabolic process#GO:0043436;biological regulation#GO:0065007;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000001206.3|UniProtKB=G3QFV7 G3QFV7 PDHX PTHR23151:SF92 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED PYRUVATE DEHYDROGENASE PROTEIN X COMPONENT, MITOCHONDRIAL membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204 transferase#PC00220;acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000003925.3|UniProtKB=G3QMV4 G3QMV4 ZFAND2A PTHR14677:SF11 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 2A primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein targeting#GO:0006605;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;proteasomal protein catabolic process#GO:0010498;establishment of protein localization to endoplasmic reticulum#GO:0072599;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000002754.3|UniProtKB=G3QJW4 G3QJW4 NGLY1 PTHR12143:SF45 PEPTIDE N-GLYCANASE PNGASE -RELATED PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 glycoprotein metabolic process#GO:0009100;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of BMP signaling pathway#GO:0030513;macromolecule metabolic process#GO:0043170;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 GORGO|Ensembl=ENSGGOG00000042992.1|UniProtKB=A0A2I2Z5Z1 A0A2I2Z5Z1 PTHR21032:SF3 G PATCH DOMAIN-CONTAINING PROTEIN 11 G PATCH DOMAIN-CONTAINING PROTEIN 11 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;system process#GO:0003008;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;multicellular organismal process#GO:0032501;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nervous system process#GO:0050877;nucleic acid biosynthetic process#GO:0141187;sensory perception#GO:0007600;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;sensory perception of light stimulus#GO:0050953;nucleic acid metabolic process#GO:0090304;visual perception#GO:0007601;RNA biosynthetic process#GO:0032774 organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000012982.3|UniProtKB=Q2IBF2 Q2IBF2 MET PTHR22625:SF61 PLEXIN HEPATOCYTE GROWTH FACTOR RECEPTOR transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;regulation of cell migration#GO:0030334;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;signaling#GO:0023052;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;response to stimulus#GO:0050896 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009162.3|UniProtKB=G3R196 G3R196 IRGQ PTHR19364:SF2 IMMUNITY-RELATED GTPASE FAMILY Q PROTEIN IMMUNITY-RELATED GTPASE FAMILY Q PROTEIN GORGO|Ensembl=ENSGGOG00000038309.1|UniProtKB=A0A2I2ZUM9 A0A2I2ZUM9 LOC101128494 PTHR24264:SF15 TRYPSIN-RELATED TRYPSIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000009730.3|UniProtKB=G3SEK6 G3SEK6 MEF2B PTHR11945:SF383 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2B histone deacetylase binding#GO:0042826;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;cell differentiation#GO:0030154;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;heart development#GO:0007507;positive regulation of macromolecule metabolic process#GO:0010604 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;CCKR signaling map#P06959>MEF2B#P07075 GORGO|Ensembl=ENSGGOG00000001319.3|UniProtKB=G3QG51 G3QG51 PTHR11829:SF310 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I3 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000021987.2|UniProtKB=G3RSZ9 G3RSZ9 MSH6 PTHR11361:SF148 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH6 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000005583.3|UniProtKB=G3QS40 G3QS40 LOC101140727 PTHR11049:SF29 ACYL COENZYME A THIOESTER HYDROLASE CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE-LIKE hydrolase activity#GO:0016787;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;monocarboxylic acid catabolic process#GO:0072329 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000006200.3|UniProtKB=G3QTN5 G3QTN5 JPT2 PTHR34930:SF5 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 2 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000001896.3|UniProtKB=G3S6Z0 G3S6Z0 VEZT PTHR15989:SF5 VEZATIN VEZATIN cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000008746.3|UniProtKB=Q7M316 Q7M316 CA1 PTHR18952:SF282 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 1 catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000025653.2|UniProtKB=A0A2I2ZUS2 A0A2I2ZUS2 PTHR11595:SF60 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-BETA guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000025912.2|UniProtKB=G3SH39 G3SH39 TMPRSS11B PTHR24253:SF56 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11B serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000010539.3|UniProtKB=G3R4R7 G3R4R7 SERPINI2 PTHR11461:SF51 SERINE PROTEASE INHIBITOR, SERPIN SERPIN I2 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000000902.3|UniProtKB=G3QF27 G3QF27 HEBP1 PTHR11220:SF22 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 1 tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;binding#GO:0005488 GORGO|Ensembl=ENSGGOG00000012633.3|UniProtKB=G3RA64 G3RA64 DPEP2 PTHR10443:SF9 MICROSOMAL DIPEPTIDASE DIPEPTIDASE 2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000016553.3|UniProtKB=A0A2I2ZM69 A0A2I2ZM69 FZD9 PTHR11309:SF79 FRIZZLED FRIZZLED-9 signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 GORGO|Ensembl=ENSGGOG00000016447.3|UniProtKB=G3RJZ5 G3RJZ5 RAVER2 PTHR23189:SF6 RNA RECOGNITION MOTIF-CONTAINING RIBONUCLEOPROTEIN PTB-BINDING 2 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000037009.1|UniProtKB=A0A2I2Z6U9 A0A2I2Z6U9 PTHR24327:SF68 HOMEOBOX PROTEIN HOMEOBOX DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;maintenance of cell number#GO:0098727;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;stem cell population maintenance#GO:0019827;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000034976.2|UniProtKB=G3SKD1 G3SKD1 PTHR34523:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 138 COILED-COIL DOMAIN-CONTAINING PROTEIN 138 GORGO|Ensembl=ENSGGOG00000012124.3|UniProtKB=G3R8V6 G3R8V6 LOC101123926 PTHR21349:SF0 50S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 ribosomal protein#PC00202 Methylcitrate cycle#P02754>Aconitase#P03028 GORGO|Gene=NDUFA13|UniProtKB=Q0MQ89 Q0MQ89 NDUFA13 PTHR12966:SF0 NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000026375.2|UniProtKB=G3SJA9 G3SJA9 DZANK1 PTHR16058:SF4 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 cellular process#GO:0009987;sensory system development#GO:0048880;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;cell development#GO:0048468;visual system development#GO:0150063;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856 GORGO|Ensembl=ENSGGOG00000001755.3|UniProtKB=G3QHA6 G3QHA6 PTBP3 PTHR15592:SF17 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000011414.3|UniProtKB=G3R710 G3R710 KIAA1671 PTHR22042:SF3 TANKYRASE 1 BINDING PROTEIN KIAA1671 HOMOLOG GORGO|Ensembl=ENSGGOG00000005920.3|UniProtKB=G3QSZ6 G3QSZ6 AWAT2 PTHR12317:SF12 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYL-COA WAX ALCOHOL ACYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;neutral lipid metabolic process#GO:0006638;primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid biosynthetic process#GO:0008610;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;biosynthetic process#GO:0009058 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000038932.1|UniProtKB=A0A2I2YPF6 A0A2I2YPF6 PTHR28562:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 GORGO|Gene=BRCA1|UniProtKB=Q6J6I8 Q6J6I8 BRCA1 PTHR13763:SF11 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN acyltransferase activity#GO:0016746;binding#GO:0005488;nucleic acid binding#GO:0003676;ubiquitin-like protein transferase activity#GO:0019787;DNA binding#GO:0003677;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;damaged DNA binding#GO:0003684;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;condensed chromosome#GO:0000793;intracellular protein-containing complex#GO:0140535;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;DNA repair complex#GO:1990391;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005717.3|UniProtKB=G3QSG3 G3QSG3 MAPKAPK5 PTHR24349:SF179 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 5 mitogen-activated protein kinase binding#GO:0051019;transferase activity#GO:0016740;calmodulin binding#GO:0005516;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;kinase binding#GO:0019900;protein serine/threonine kinase activity#GO:0004674;enzyme binding#GO:0019899;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000024845.2|UniProtKB=A0A2I2Y405 A0A2I2Y405 PDLIM5 PTHR24214:SF32 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 5 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;heart development#GO:0007507;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731 cytoskeleton#GO:0005856;stress fiber#GO:0001725;actin filament#GO:0005884;I band#GO:0031674;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;sarcomere#GO:0030017;cell junction#GO:0030054;adherens junction#GO:0005912;cell-cell junction#GO:0005911;Z disc#GO:0030018;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000008946.3|UniProtKB=G3R0R4 G3R0R4 MARF1 PTHR14379:SF93 LIMKAIN B LKAP MEIOSIS REGULATOR AND MRNA STABILITY FACTOR 1 protein-containing complex binding#GO:0044877;binding#GO:0005488 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000040889.1|UniProtKB=A0A2I2Z0P3 A0A2I2Z0P3 PTHR14499:SF119 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING SUBFAMILY NOT NAMED transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000073.3|UniProtKB=G3QCX0 G3QCX0 ZC3H15 PTHR12681:SF0 ZINC FINGER-CONTAINING PROTEIN P48ZNF ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15 cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000040834.1|UniProtKB=A0A2I2Z0K9 A0A2I2Z0K9 BHLHE23 PTHR19290:SF53 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 23 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000042736.1|UniProtKB=A0A2I2ZH92 A0A2I2ZH92 PTHR11588:SF429 TUBULIN TUBULIN BETA 8B-RELATED nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 tubulin#PC00228;cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 GORGO|Ensembl=ENSGGOG00000012620.3|UniProtKB=G3RA61 G3RA61 SUSD1 PTHR24051:SF5 SUSHI DOMAIN-CONTAINING PROTEIN 1 SUSHI DOMAIN-CONTAINING PROTEIN 1 extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000028326.2|UniProtKB=G3RR69 G3RR69 LOC101151540 PTHR10871:SF32 30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN US13 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007000.3|UniProtKB=A0A2I2ZAQ0 A0A2I2ZAQ0 PTHR12400:SF55 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE A phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000006627.3|UniProtKB=G3S5J1 G3S5J1 MAP10 PTHR21831:SF2 MICROTUBULE-ASSOCIATED PROTEIN 10 MICROTUBULE-ASSOCIATED PROTEIN 10 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cellular component assembly#GO:0022607;positive regulation of cell cycle#GO:0045787;spindle elongation#GO:0051231;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059;cytoplasmic microtubule organization#GO:0031122;mitotic spindle organization#GO:0007052;regulation of cell cycle#GO:0051726;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cytokinesis#GO:0032465;nuclear division#GO:0000280;biological regulation#GO:0065007;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;positive regulation of cellular process#GO:0048522;spindle organization#GO:0007051;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of cell division#GO:0051302;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;spindle pole#GO:0000922;midbody#GO:0030496;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000028205.2|UniProtKB=G3SJ90 G3SJ90 PYURF PTHR33505:SF7 ZGC:162634 PROTEIN PREY, MITOCHONDRIAL GORGO|Ensembl=ENSGGOG00000000356.3|UniProtKB=G3QDM7 G3QDM7 NUFIP1 PTHR13309:SF1 NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1 FMR1-INTERACTING PROTEIN NUFIP1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-RNA complex assembly#GO:0022618;protein-containing complex organization#GO:0043933 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000027960.2|UniProtKB=A0A2I2YCQ2 A0A2I2YCQ2 H3-4 PTHR11426:SF276 HISTONE H3 HISTONE H3.1T metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;organelle localization#GO:0051640;nuclear division#GO:0000280;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382;organelle fission#GO:0048285;kinetochore organization#GO:0051383;localization#GO:0051179;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;mitotic cell cycle#GO:0000278 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 GORGO|Ensembl=ENSGGOG00000007490.3|UniProtKB=A0A2I2YBN2 A0A2I2YBN2 SLC41A3 PTHR16228:SF22 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012131.3|UniProtKB=G3R8W9 G3R8W9 IGHMBP2 PTHR43788:SF20 DNA2/NAM7 HELICASE FAMILY MEMBER DNA-BINDING PROTEIN SMUBP-2 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000009064.3|UniProtKB=G3R124 G3R124 HEPH PTHR11709:SF221 MULTI-COPPER OXIDASE HEPHAESTIN oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722;catalytic activity#GO:0003824 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000005403.3|UniProtKB=G3QRN0 G3QRN0 SPATA19 PTHR36468:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 19, MITOCHONDRIAL SPERMATOGENESIS-ASSOCIATED PROTEIN 19, MITOCHONDRIAL cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 GORGO|Ensembl=ENSGGOG00000008814.3|UniProtKB=G3R0D3 G3R0D3 ZACN PTHR18945:SF912 NEUROTRANSMITTER GATED ION CHANNEL LIGAND-GATED CATION CHANNEL ZACN molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215 metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000006560.3|UniProtKB=G3QUL4 G3QUL4 LOC101128292 PTHR26454:SF12 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6F1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015767.3|UniProtKB=G3RI94 G3RI94 LARS2 PTHR43740:SF3 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000009702.3|UniProtKB=A0A2I2Y4V8 A0A2I2Y4V8 TMEM14B PTHR12668:SF34 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14B porphyrin-containing compound biosynthetic process#GO:0006779;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014;cellular process#GO:0009987;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000004101.3|UniProtKB=G3QNB3 G3QNB3 C23H22orf39 PTHR28052:SF1 UPF0545 PROTEIN C22ORF39 SYNAPTIC PLASTICITY REGULATOR PANTS GORGO|Ensembl=ENSGGOG00000008112.4|UniProtKB=G3QYJ9 G3QYJ9 BBS9 PTHR20991:SF0 PARATHYROID HORMONE-RESPONSIVE B1 GENE PROTEIN PTHB1 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 membrane#GO:0016020;BBSome#GO:0034464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000016818.3|UniProtKB=G3RKX4 G3RKX4 TEX101 PTHR16529:SF3 CD177 ANTIGEN TESTIS-EXPRESSED PROTEIN 101 regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;fertilization#GO:0009566;reproductive process#GO:0022414;regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;binding of sperm to zona pellucida#GO:0007339;regulation of microtubule-based process#GO:0032886;sexual reproduction#GO:0019953;cell recognition#GO:0008037;regulation of reproductive process#GO:2000241;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;single fertilization#GO:0007338;cellular process#GO:0009987;cell-cell recognition#GO:0009988;sperm-egg recognition#GO:0035036 membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853;membrane#GO:0016020;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000015876.3|UniProtKB=G3RII2 G3RII2 MARCHF11 PTHR46053:SF1 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF11 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000022230.2|UniProtKB=G3S1D3 G3S1D3 GIMAP2 PTHR10903:SF7 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 2 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000009626.3|UniProtKB=G3S5I2 G3S5I2 ADAMTS10 PTHR13723:SF26 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 10 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000005437.3|UniProtKB=G3QRR5 G3QRR5 NEBL PTHR11039:SF48 NEBULIN NEBULETTE binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;system development#GO:0048731;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;actin filament organization#GO:0007015;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cardiac muscle cell differentiation#GO:0055007;cellular component assembly#GO:0022607;heart development#GO:0007507;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513 myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;I band#GO:0031674;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;Z disc#GO:0030018;contractile muscle fiber#GO:0043292 GORGO|Ensembl=ENSGGOG00000000111.3|UniProtKB=G3SBP0 G3SBP0 ARSI PTHR10342:SF68 ARYLSULFATASE ARYLSULFATASE I hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 GORGO|Ensembl=ENSGGOG00000041829.1|UniProtKB=A0A2I2ZQ86 A0A2I2ZQ86 TMCO1 PTHR20917:SF1 PNAS-RELATED CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 GORGO|Ensembl=ENSGGOG00000007761.3|UniProtKB=G3QXN9 G3QXN9 PTHR22702:SF3 PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000002734.3|UniProtKB=A0A2I2YF80 A0A2I2YF80 NUP88 PTHR13257:SF0 NUCLEOPORIN NUP84-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP88 ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;ribosomal large subunit export from nucleus#GO:0000055;protein transport#GO:0015031;protein import into nucleus#GO:0006606;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;ribosome biogenesis#GO:0042254;protein export from nucleus#GO:0006611;gene expression#GO:0010467;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;organelle localization#GO:0051640;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907 nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000005855.4|UniProtKB=A0A2I2ZXC9 A0A2I2ZXC9 RTN1 PTHR45799:SF5 RETICULON-LIKE PROTEIN RETICULON-1 cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000027993.2|UniProtKB=A0A2I2ZT75 A0A2I2ZT75 PTHR21551:SF10 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PAT1 HOMOLOG 1, PROCESSING BODY MRNA DECAY FACTOR molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;cellular component assembly#GO:0022607;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;catabolic process#GO:0009056;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;organelle assembly#GO:0070925;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of gene expression#GO:0010468;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;negative regulation of protein metabolic process#GO:0051248;primary metabolic process#GO:0044238;P-body assembly#GO:0033962;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;P-body#GO:0000932;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012955.3|UniProtKB=A0A2I2ZHZ9 A0A2I2ZHZ9 FSD1 PTHR24099:SF4 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 1 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 regulation of mitotic spindle organization#GO:0060236;regulation of microtubule-based process#GO:0032886;regulation of cell division#GO:0051302;regulation of cellular component organization#GO:0051128;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000037898.1|UniProtKB=A0A2I2YIE0 A0A2I2YIE0 PTHR15367:SF5 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT cell population proliferation#GO:0008283;cellular process#GO:0009987 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666 DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000013322.3|UniProtKB=G3RBX7 G3RBX7 FKBP3 PTHR46493:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000004762.3|UniProtKB=G3QQ09 G3QQ09 CPQ PTHR12053:SF6 PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED CARBOXYPEPTIDASE Q metallopeptidase activity#GO:0008237;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 peptide metabolic process#GO:0006518;regulation of biological quality#GO:0065008;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biological regulation#GO:0065007;catabolic process#GO:0009056;hormone metabolic process#GO:0042445;phenol-containing compound metabolic process#GO:0018958;peptide catabolic process#GO:0043171;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008288.3|UniProtKB=G3QZ06 G3QZ06 SUN5 PTHR12911:SF44 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane#GO:0016020;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000007087.3|UniProtKB=A0A2I2ZUB8 A0A2I2ZUB8 BRAP PTHR24007:SF7 BRCA1-ASSOCIATED PROTEIN BRCA1-ASSOCIATED PROTEIN ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;signal transduction#GO:0007165;cellular process#GO:0009987;protein ubiquitination#GO:0016567;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;post-translational protein modification#GO:0043687;Ras protein signal transduction#GO:0007265;protein modification by small protein conjugation or removal#GO:0070647;cell communication#GO:0007154;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;intracellular signal transduction#GO:0035556;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002435.3|UniProtKB=G3SG42 G3SG42 DCDC1 PTHR46302:SF3 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 1 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;regulation of mitotic cytokinesis#GO:1902412;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;midbody#GO:0030496 GORGO|Ensembl=ENSGGOG00000001760.3|UniProtKB=A0A2I2YXY6 A0A2I2YXY6 IAH1 PTHR14209:SF19 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 GORGO|Ensembl=ENSGGOG00000009597.3|UniProtKB=G3R2C6 G3R2C6 LRRC57 PTHR47186:SF72 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57 GORGO|Ensembl=ENSGGOG00000007536.3|UniProtKB=A0A2I2YCT7 A0A2I2YCT7 TMCC3 PTHR17613:SF8 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN PROTEIN 3 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010506.3|UniProtKB=G3R4P1 G3R4P1 LOC101133451 PTHR10266:SF3 CYTOCHROME C1 CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Huntington disease#P00029>Cytochrome c#P00785;FAS signaling pathway#P00020>CytochromeC#P00620;ATP synthesis#P02721>Cyt bc1#P02799 GORGO|Ensembl=ENSGGOG00000013047.3|UniProtKB=G3RB90 G3RB90 PRKAB1 PTHR10343:SF96 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 GORGO|Ensembl=ENSGGOG00000016530.3|UniProtKB=G3RK68 G3RK68 PSMC3 PTHR23073:SF90 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6A isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190 GORGO|Ensembl=ENSGGOG00000023531.2|UniProtKB=G3RSU1 G3RSU1 C1H1orf56 PTHR16240:SF2 PROTEIN MENT PROTEIN MENT GORGO|Ensembl=ENSGGOG00000015353.3|UniProtKB=G3RMZ4 G3RMZ4 MRPL10 PTHR11560:SF12 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL10M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000000109.3|UniProtKB=G3QD04 G3QD04 THPO PTHR10560:SF0 THROMBOPOIETIN THROMBOPOIETIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of cell population proliferation#GO:0042127;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;cellular response to chemokine#GO:1990869;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;response to chemical#GO:0042221;regulation of ERK1 and ERK2 cascade#GO:0070372;response to cytokine#GO:0034097;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to chemokine#GO:1990868;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell population proliferation#GO:0008284 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000001064.3|UniProtKB=G3QFH4 G3QFH4 NOP10 PTHR13305:SF0 RIBOSOME BIOGENESIS PROTEIN NOP10 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;snRNA metabolic process#GO:0016073;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001490.3|UniProtKB=G3QGL5 G3QGL5 C17H18orf54 PTHR35079:SF1 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 GORGO|Ensembl=ENSGGOG00000004376.3|UniProtKB=G3QP10 G3QP10 VSTM4 PTHR12207:SF8 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4 cellular anatomical structure#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000011410.3|UniProtKB=G3R704 G3R704 MMP21 PTHR10201:SF340 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-21 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000002691.3|UniProtKB=G3QJQ3 G3QJQ3 RADIL PTHR16027:SF3 DILUTE DOMAIN-CONTAINING PROTEIN YPR089W RAS-ASSOCIATING AND DILUTE DOMAIN-CONTAINING PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515 neural crest cell development#GO:0014032;cell migration#GO:0016477;tissue development#GO:0009888;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;cellular process#GO:0009987;animal organ development#GO:0048513;cellular developmental process#GO:0048869;mesenchyme development#GO:0060485;mesenchymal cell differentiation#GO:0048762;neural crest cell differentiation#GO:0014033;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cell motility#GO:0048870;cell differentiation#GO:0030154;cell development#GO:0048468;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;animal gross anatomical part developmental process#GO:0160108;stem cell development#GO:0048864;cell adhesion#GO:0007155 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000013507.3|UniProtKB=G3RCE7 G3RCE7 LAGE3 PTHR31283:SF19 EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER EKC_KEOPS COMPLEX SUBUNIT LAGE3 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000040323.1|UniProtKB=A0A2I2ZTF8 A0A2I2ZTF8 FZD7 PTHR11309:SF31 FRIZZLED FRIZZLED-7 protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428 GORGO|Ensembl=ENSGGOG00000010515.3|UniProtKB=G3R4P8 G3R4P8 KLRD1 PTHR22800:SF260 C-TYPE LECTIN PROTEINS NATURAL KILLER CELLS ANTIGEN CD94 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of cell killing#GO:0031341;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;natural killer cell mediated immunity#GO:0002228;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;defense response#GO:0006952;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;response to other organism#GO:0051707;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of immune effector process#GO:0002697;cell communication#GO:0007154;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;innate immune response-activating signaling pathway#GO:0002758;regulation of natural killer cell mediated immunity#GO:0002715;cellular response to stimulus#GO:0051716;regulation of leukocyte mediated immunity#GO:0002703;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of natural killer cell mediated immunity#GO:0002717;response to external biotic stimulus#GO:0043207 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000919.3|UniProtKB=G3QF42 G3QF42 MRGPRE PTHR11334:SF26 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER E signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000001682.3|UniProtKB=G3QH36 G3QH36 VAPA PTHR10809:SF155 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;developmental process#GO:0032502;endoplasmic reticulum membrane organization#GO:0090158;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000004704.3|UniProtKB=G3QPV1 G3QPV1 IL13 PTHR48486:SF1 INTERLEUKIN-13 INTERLEUKIN-13 signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein binding#GO:0005515 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;inflammatory response#GO:0006954;regulation of immune effector process#GO:0002697;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;defense response#GO:0006952;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Interleukin signaling pathway#P00036>Interleukin#P00970;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 GORGO|Ensembl=ENSGGOG00000013929.3|UniProtKB=G3RDI3 G3RDI3 ADIPOR2 PTHR20855:SF33 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>AdipoR1/R2#P06706 GORGO|Ensembl=ENSGGOG00000016097.3|UniProtKB=G3RVJ6 G3RVJ6 ZCCHC18 PTHR23095:SF48 PARANEOPLASTIC ANTIGEN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 18 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000040661.1|UniProtKB=A0A2I2YNB8 A0A2I2YNB8 PTHR43948:SF15 DNAJ HOMOLOG SUBFAMILY B J DOMAIN-CONTAINING PROTEIN protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000010169.3|UniProtKB=G3R3U5 G3R3U5 STRN4 PTHR15653:SF1 STRIATIN STRIATIN-4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;cell body#GO:0044297;neuron projection#GO:0043005 GORGO|Ensembl=ENSGGOG00000010921.3|UniProtKB=A0A2I2YYH8 A0A2I2YYH8 UBALD1 PTHR31993:SF5 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000000910.3|UniProtKB=G3QF33 G3QF33 OR4Q3 PTHR26453:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026833.2|UniProtKB=G3S6S5 G3S6S5 UGT2B15 PTHR48043:SF64 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2B15 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 GORGO|Ensembl=ENSGGOG00000008649.3|UniProtKB=G3QZZ0 G3QZZ0 ANAPC5 PTHR12830:SF9 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of cell cycle phase transition#GO:1901987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of cellular component organization#GO:0051130;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638;protein K11-linked ubiquitination#GO:0070979;positive regulation of cell cycle process#GO:0090068;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of chromosome separation#GO:1905818;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000036582.1|UniProtKB=A0A2I2YDL0 A0A2I2YDL0 FPGT PTHR15045:SF1 FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 organophosphate biosynthetic process#GO:0090407;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000006953.3|UniProtKB=G3QVM2 G3QVM2 KLRK1 PTHR47494:SF1 NKG2-D TYPE II INTEGRAL MEMBRANE PROTEIN NKG2-D TYPE II INTEGRAL MEMBRANE PROTEIN GORGO|Ensembl=ENSGGOG00000008246.3|UniProtKB=G3QYW9 G3QYW9 ADGRF5 PTHR45813:SF13 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 glucose homeostasis#GO:0042593;multicellular organismal-level homeostasis#GO:0048871;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;chemical homeostasis#GO:0048878;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;energy reserve metabolic process#GO:0006112;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;homeostatic process#GO:0042592;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;carbohydrate homeostasis#GO:0033500;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000012935.3|UniProtKB=G3RAY3 G3RAY3 ZNF559 PTHR24393:SF187 ZINC FINGER PROTEIN ZINC FINGER PROTEIN DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008501.3|UniProtKB=G3QZJ9 G3QZJ9 ZNFX1 PTHR10887:SF341 DNA2/NAM7 HELICASE FAMILY NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000024282.2|UniProtKB=A0A2I2YAD4 A0A2I2YAD4 THOC7 PTHR23405:SF5 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED THO COMPLEX SUBUNIT 7 nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transcription export complex#GO:0000346;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011732.3|UniProtKB=G3R7U2 G3R7U2 TAFA1 PTHR31770:SF2 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-1 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 developmental process#GO:0032502;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;chemokine#PC00074 GORGO|Ensembl=ENSGGOG00000006315.3|UniProtKB=G3QTZ1 G3QTZ1 PLEKHA4 PTHR12752:SF7 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 4 phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289 positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002477.3|UniProtKB=G3SFB7 G3SFB7 NINL PTHR18905:SF12 NINEIN NINEIN-LIKE PROTEIN cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;microtubule cytoskeleton organization#GO:0000226;microtubule anchoring#GO:0034453;microtubule-based process#GO:0007017 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 PDGF signaling pathway#P00047>GSK3#P01153 GORGO|Ensembl=ENSGGOG00000001296.3|UniProtKB=G3QG27 G3QG27 DGAT2L6 PTHR12317:SF19 DIACYLGLYCEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 2-LIKE PROTEIN 6 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;neutral lipid metabolic process#GO:0006638 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000011492.3|UniProtKB=G3R778 G3R778 FAIM PTHR13088:SF3 FAS APOPTOTIC INHIBITORY MOLECULE FAIM FAS APOPTOTIC INHIBITORY MOLECULE 1 negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of programmed cell death#GO:0043069;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237 GORGO|Ensembl=ENSGGOG00000024857.2|UniProtKB=G3S1S2 G3S1S2 PTHR13633:SF3 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000027672.2|UniProtKB=A0A2I2YIG2 A0A2I2YIG2 PTHR11560:SF13 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL10M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000008361.3|UniProtKB=G3QZ81 G3QZ81 COL20A1 PTHR24020:SF39 COLLAGEN ALPHA COLLAGEN ALPHA-1(XX) CHAIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000012360.3|UniProtKB=A0A2I2Z7I9 A0A2I2Z7I9 NXPH1 PTHR17103:SF13 NEUREXOPHILIN NEUREXOPHILIN-1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;GABA-ergic synapse#GO:0098982 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000025796.2|UniProtKB=G3RTL2 G3RTL2 PTHR24369:SF160 ANTIGEN BSP, PUTATIVE-RELATED VASORIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000006706.3|UniProtKB=G3QV08 G3QV08 ARVCF PTHR10372:SF5 PLAKOPHILLIN-RELATED SPLICING REGULATOR ARVCF binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;intermediate filament#PC00129;intermediate filament binding protein#PC00130 GORGO|Ensembl=ENSGGOG00000005172.3|UniProtKB=A0A2I2ZGP3 A0A2I2ZGP3 CCNH PTHR10026:SF8 CYCLIN CYCLIN-H enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 kinase activator#PC00138;kinase modulator#PC00140 GORGO|Ensembl=ENSGGOG00000008046.3|UniProtKB=G3RRX4 G3RRX4 GPR182 PTHR24226:SF0 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 ATYPICAL CHEMOKINE RECEPTOR 5 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000008809.3|UniProtKB=G3R0C8 G3R0C8 UCHL1 PTHR10589:SF19 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>UCH-L1#P01210 GORGO|Ensembl=ENSGGOG00000025164.2|UniProtKB=G3RP35 G3RP35 ADD3 PTHR10672:SF5 ADDUCIN GAMMA-ADDUCIN binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of actin filament depolymerization#GO:0030834;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of protein depolymerization#GO:1901879;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833 cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000005145.3|UniProtKB=G3QR19 G3QR19 PTHR23302:SF35 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 3 passive transmembrane transporter activity#GO:0022803;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000008353.3|UniProtKB=G3SC57 G3SC57 ARFGAP1 PTHR46395:SF1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of intracellular signal transduction#GO:1902531;regulation of endocytosis#GO:0030100;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 GTPase-activating protein#PC00257;G-protein modulator#PC00022 Integrin signalling pathway#P00034>ASAP1#P00909 GORGO|Ensembl=ENSGGOG00000043095.1|UniProtKB=A0A2I2Y3H6 A0A2I2Y3H6 PTHR24031:SF663 RNA HELICASE ATP-DEPENDENT RNA HELICASE cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013385.3|UniProtKB=G3RC33 G3RC33 HSPB8 PTHR46906:SF1 HEAT SHOCK PROTEIN BETA-8 HEAT SHOCK PROTEIN BETA-8 cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cellular response to unfolded protein#GO:0034620;response to unfolded protein#GO:0006986;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein folding chaperone complex#GO:0101031;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000022312.2|UniProtKB=G3S0Y7 G3S0Y7 SFRP4 PTHR11309:SF7 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 4 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>FrzB#P01461 GORGO|Ensembl=ENSGGOG00000011631.3|UniProtKB=G3R7K6 G3R7K6 ANP32B PTHR11375:SF2 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER B binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000037296.1|UniProtKB=A0A2I2YT94 A0A2I2YT94 CNTNAP2 PTHR15036:SF33 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 2 biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;multicellular organism development#GO:0007275;developmental process#GO:0032502;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;nervous system process#GO:0050877;animal gross anatomical part developmental process#GO:0160108;cognition#GO:0050890 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000002496.3|UniProtKB=G3QJ79 G3QJ79 SEC24D PTHR13803:SF6 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24D cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;SNARE binding#GO:0000149;zinc ion binding#GO:0008270 vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;coated membrane#GO:0048475;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000000731.3|UniProtKB=G3QEM3 G3QEM3 ZFP37 PTHR24381:SF390 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 37 HOMOLOG transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006684.3|UniProtKB=G3QUX9 G3QUX9 PTHR21600:SF40 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD2 intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000015234.3|UniProtKB=A0A2I2Z2H0 A0A2I2Z2H0 C5H6orf120 PTHR31703:SF2 UPF0669 PROTEIN C6ORF120 UPF0669 PROTEIN C6ORF120 GORGO|Ensembl=ENSGGOG00000005969.3|UniProtKB=G3QT37 G3QT37 CFAP44 PTHR14885:SF3 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 44 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824 male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782 organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000040822.1|UniProtKB=A0A2I2ZRH2 A0A2I2ZRH2 PTHR12758:SF22 APOPTOSIS INHIBITOR 5-RELATED APOPTOSIS INHIBITOR 5 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009304.3|UniProtKB=G3R1L0 G3R1L0 BCL9 PTHR15185:SF5 BCL9 B-CELL CLL_LYMPHOMA 9 PROTEIN binding#GO:0005488;protein binding#GO:0005515;beta-catenin binding#GO:0008013 response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 Wnt signaling pathway#P00057>Bcl9#P01450 GORGO|Ensembl=ENSGGOG00000005714.3|UniProtKB=G3QSG6 G3QSG6 MAP3K20 PTHR23257:SF937 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;regulation of MAPK cascade#GO:0043408;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of chromosome segregation#GO:0051985;negative regulation of cell cycle#GO:0045786;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell cycle phase transition#GO:1901987;regulation of cell communication#GO:0010646;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of reproductive process#GO:2000241;positive regulation of response to stimulus#GO:0048584;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cell cycle process#GO:0010948;regulation of response to stimulus#GO:0048583;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of chromosome separation#GO:1905819;positive regulation of MAPK cascade#GO:0043410 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009288.3|UniProtKB=G3R1J8 G3R1J8 PTHR46727:SF1 E3 SUMO-PROTEIN LIGASE CBX4 E3 SUMO-PROTEIN LIGASE CBX4 binding#GO:0005488;acyltransferase activity#GO:0016746;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;post-translational protein modification#GO:0043687;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;metabolic process#GO:0008152;protein sumoylation#GO:0016925;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005880.3|UniProtKB=G3QSV6 G3QSV6 TLX1 PTHR45921:SF2 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000001603.3|UniProtKB=G3QGW6 G3QGW6 EIF2S1 PTHR10602:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 translation factor activity#GO:0180051;binding#GO:0005488;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;translation initiation factor activity#GO:0003743;ribonucleoprotein complex binding#GO:0043021 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904 translation initiation factor#PC00224;translation factor#PC00223 Apoptosis signaling pathway#P00006>ELF2alpha#P00307 GORGO|Ensembl=ENSGGOG00000002717.3|UniProtKB=G3RUS7 G3RUS7 DYDC1 PTHR23356:SF4 DPY30-RELATED DPY30 DOMAIN-CONTAINING PROTEIN 1 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;male gamete generation#GO:0048232;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;cellular anatomical entity morphogenesis#GO:0032989;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;vesicle organization#GO:0016050;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;germ cell development#GO:0007281;anatomical structure morphogenesis#GO:0009653;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;spermatid differentiation#GO:0048515;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;spermatid development#GO:0007286;acrosome assembly#GO:0001675;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609 cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;radial spoke#GO:0001534;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014 GORGO|Ensembl=ENSGGOG00000011741.3|UniProtKB=G3R7V7 G3R7V7 HDAC1 PTHR10625:SF49 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 1 deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824 negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338 SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>Histone deacetylase#P01472;p53 pathway#P00059>HDAC1#P04612 GORGO|Ensembl=ENSGGOG00000005730.3|UniProtKB=G3QSH6 G3QSH6 PDE6B PTHR11347:SF73 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT BETA hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 regulation of cell communication#GO:0010646;visual system development#GO:0150063;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;negative regulation of signaling#GO:0023057;retina development in camera-type eye#GO:0060041;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;plasma membrane region#GO:0098590;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;cilium#GO:0005929;cell projection membrane#GO:0031253;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 phosphodiesterase#PC00185;hydrolase#PC00121 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEalphabeta#P00759 GORGO|Ensembl=ENSGGOG00000004540.3|UniProtKB=G3QPG2 G3QPG2 MAP3K14 PTHR48016:SF9 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>NIK#P00324;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;CCKR signaling map#P06959>MAP3K14#P07063 GORGO|Ensembl=ENSGGOG00000008426.3|UniProtKB=G3QZD0 G3QZD0 VSIR PTHR44819:SF1 V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION negative regulation of T cell activation#GO:0050868;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of lymphocyte activation#GO:0051249;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of cell activation#GO:0050866;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of T cell activation#GO:0050863;regulation of cell adhesion#GO:0030155;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of cell adhesion#GO:0007162;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000003420.3|UniProtKB=A0A2I2YYU7 A0A2I2YYU7 JAKMIP2 PTHR18935:SF7 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000038444.1|UniProtKB=A0A2I2Z7V1 A0A2I2Z7V1 PSME1 PTHR10660:SF5 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;endopeptidase regulator activity#GO:0061135;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134 regulation of mitotic cell cycle phase transition#GO:1901990;regulation of protein catabolic process#GO:0042176;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of mitotic cell cycle#GO:0007346 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000024537.2|UniProtKB=A0A2I2ZGH7 A0A2I2ZGH7 PROK2 PTHR18821:SF8 PROKINETICIN PROKINETICIN-2 endothelial cell proliferation#GO:0001935;epithelial cell proliferation#GO:0050673;cellular process#GO:0009987;cell population proliferation#GO:0008283 peptide hormone#PC00179 GORGO|Gene=SP100|UniProtKB=Q9N1Q6 Q9N1Q6 SP100 PTHR48112:SF18 HIGH MOBILITY GROUP PROTEIN DSP1 SUBFAMILY NOT NAMED cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000008811.3|UniProtKB=G3R0D1 G3R0D1 TTC17 PTHR16091:SF1 TTC17 PROTEIN TETRATRICOPEPTIDE REPEAT PROTEIN 17 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cilium organization#GO:0044782;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016633.3|UniProtKB=G3RKG2 G3RKG2 ATG5 PTHR13040:SF2 AUTOPHAGY PROTEIN 5 AUTOPHAGY PROTEIN 5 ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;autophagosome#GO:0005776 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000025449.2|UniProtKB=G3RW80 G3RW80 ZNF200 PTHR47772:SF1 ZINC FINGER PROTEIN 200 ZINC FINGER PROTEIN 200 GORGO|Ensembl=ENSGGOG00000008448.3|UniProtKB=G3QZF4 G3QZF4 CYLD PTHR11830:SF15 40S RIBOSOMAL PROTEIN S3A UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD structural constituent of ribosome#GO:0003735;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;structural molecule activity#GO:0005198;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;translation#GO:0006412;protein modification by small protein conjugation or removal#GO:0070647;regulation of intracellular signal transduction#GO:1902531;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of biological process#GO:0050789;regulation of intrinsic apoptotic signaling pathway#GO:2001242;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;protein modification process#GO:0036211;programmed cell death#GO:0012501;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;necroptotic process#GO:0070266;regulation of signal transduction#GO:0009966;biosynthetic process#GO:0009058;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;gene expression#GO:0010467 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000001247.3|UniProtKB=G3QFZ0 G3QFZ0 TMPRSS11F PTHR24253:SF65 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11F catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000005025.3|UniProtKB=A0A2I2ZXB2 A0A2I2ZXB2 SLC25A37 PTHR45758:SF4 MITOFERRIN-1-RELATED MITOFERRIN-1 transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;iron ion transmembrane transporter activity#GO:0005381;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;transport#GO:0006810;iron ion transport#GO:0006826;iron ion transmembrane transport#GO:0034755;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000004811.3|UniProtKB=A0A2I2YMV6 A0A2I2YMV6 UBE2D1 PTHR24068:SF36 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D1 ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000043383.1|UniProtKB=A0A2I2Z6L9 A0A2I2Z6L9 PTHR21100:SF9 PREFOLDIN SUBUNIT 4 PREFOLDIN SUBUNIT 4 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000008478.3|UniProtKB=G3QZH7 G3QZH7 OARD1 PTHR12521:SF0 PROTEIN C6ORF130 ADP-RIBOSE GLYCOHYDROLASE OARD1 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleoside metabolic process#GO:0042278;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;nucleoside metabolic process#GO:0009116;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative metabolic process#GO:1901135 chromosome#GO:0005694;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000024458.2|UniProtKB=G3RVX9 G3RVX9 PTHR14224:SF110 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 MELANOMA ANTIGEN PREFERENTIALLY EXPRESSED IN TUMORS ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462 GORGO|Ensembl=ENSGGOG00000000836.3|UniProtKB=G3QEX0 G3QEX0 IL6R PTHR23036:SF98 CYTOKINE RECEPTOR INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000008682.3|UniProtKB=G3R009 G3R009 PTHR22674:SF4 NTPASE, KAP FAMILY P-LOOP DOMAIN-CONTAINING 1 NTPASE KAP FAMILY P-LOOP DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000007165.3|UniProtKB=G3QW68 G3QW68 ARHGEF40 PTHR45845:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 40 guanyl-nucleotide exchange factor#PC00113 GORGO|Gene=MT-ND3|UniProtKB=Q9T9Y5 Q9T9Y5 MT-ND3 PTHR11058:SF26 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;electron transfer activity#GO:0009055;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;NADH dehydrogenase activity#GO:0003954 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000025093.2|UniProtKB=G3SAK3 G3SAK3 LOC101141038 PTHR23413:SF6 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N LARGE RIBOSOMAL SUBUNIT PROTEIN EL32 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000037803.1|UniProtKB=A0A2I2YD89 A0A2I2YD89 CCND1 PTHR10177:SF67 CYCLINS G1_S-SPECIFIC CYCLIN-D1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082 transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase activator#PC00138 CCKR signaling map#P06959>CCND1#G07280;CCKR signaling map#P06959>CCND1#G06986;Cell cycle#P00013>Cyclin D#P00484;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;PI3 kinase pathway#P00048>Cyclin d#G01546 GORGO|Ensembl=ENSGGOG00000008585.3|UniProtKB=G3QZT8 G3QZT8 MYO5B PTHR13140:SF356 MYOSIN UNCONVENTIONAL MYOSIN-VB polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000042340.1|UniProtKB=A0A2I2ZTG6 A0A2I2ZTG6 PTHR23048:SF55 MYOSIN LIGHT CHAIN 1, 3 MYL6 ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;structural molecule activity#GO:0005198;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000000459.3|UniProtKB=G3QDX1 G3QDX1 PTHR24300:SF1 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2D6-RELATED tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular response to xenobiotic stimulus#GO:0071466;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;arachidonate metabolic process#GO:0019369;cellular response to stimulus#GO:0051716;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;olefinic compound metabolic process#GO:0120254 intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005716.3|UniProtKB=G3RN00 G3RN00 RHPN1 PTHR23031:SF6 RHOPHILIN RHOPHILIN-1 negative regulation of cytoskeleton organization#GO:0051494;negative regulation of biological process#GO:0048519;regulation of actin filament bundle assembly#GO:0032231;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000014730.3|UniProtKB=G3S7N6 G3S7N6 CD1A PTHR16675:SF160 MHC CLASS I-RELATED T-CELL SURFACE GLYCOPROTEIN CD1A lipid binding#GO:0008289;antigen binding#GO:0003823;binding#GO:0005488 regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000010727.3|UniProtKB=A0A2I2Y5M2 A0A2I2Y5M2 SLCO2A1 PTHR11388:SF14 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 lipid localization#GO:0010876;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011560.3|UniProtKB=G3R7E6 G3R7E6 CLSTN3 PTHR14139:SF5 CALSYNTENIN CALSYNTENIN-3 cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515 positive regulation of developmental process#GO:0051094;positive regulation of synapse assembly#GO:0051965;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of synapse assembly#GO:0051963;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013369.3|UniProtKB=A0A2K5TIY1 A0A2K5TIY1 NDUFA2 PTHR12878:SF1 NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 2 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000014808.3|UniProtKB=A0A2I2ZDW4 A0A2I2ZDW4 PTPRJ PTHR19134:SF554 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ETA phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000007471.3|UniProtKB=G3QWZ6 G3QWZ6 LOC101152981 PTHR23220:SF79 INTEGRIN ALPHA INTEGRIN ALPHA-E signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000014272.4|UniProtKB=A0A2I2ZKN0 A0A2I2ZKN0 TOM1 PTHR13856:SF32 VHS DOMAIN CONTAINING PROTEIN FAMILY TARGET OF MYB1 MEMBRANE TRAFFICKING PROTEIN binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000010006.3|UniProtKB=G3R3E0 G3R3E0 LSM3 PTHR13110:SF15 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;U4/U6 x U5 tri-snRNP complex#GO:0046540;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;P-body#GO:0000932;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000026585.2|UniProtKB=A0A2I2YSK7 A0A2I2YSK7 LOC101132020 PTHR23105:SF128 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER 60S RIBOSOMAL PROTEIN L7A nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016258.3|UniProtKB=G3RJH1 G3RJH1 GLYR1 PTHR43580:SF10 OXIDOREDUCTASE GLYR1-RELATED CYTOKINE-LIKE NUCLEAR FACTOR N-PAC DNA binding#GO:0003677;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000037289.1|UniProtKB=A0A2I2YEF3 A0A2I2YEF3 PTHR23158:SF58 MELANOMA INHIBITORY ACTIVITY-RELATED MIA SH3 DOMAIN ER EXPORT FACTOR 2 establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;secretion by cell#GO:0032940;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;protein secretion#GO:0009306;export from cell#GO:0140352;protein localization to extracellular region#GO:0071692 organelle membrane#GO:0031090;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000039746.1|UniProtKB=A0A2I2YUY8 A0A2I2YUY8 TINF2 PTHR15512:SF0 TERF1-INTERACTING NUCLEAR FACTOR 2 TERF1-INTERACTING NUCLEAR FACTOR 2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;telomere capping#GO:0016233;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of telomere maintenance via telomere lengthening#GO:1904356;chromosome organization#GO:0051276;regulation of telomere maintenance#GO:0032204;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of chromosome organization#GO:0033044;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;telomere organization#GO:0032200 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear telomere cap complex#GO:0000783;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;nucleus#GO:0005634;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000040399.1|UniProtKB=A0A2I2ZTG0 A0A2I2ZTG0 ZNF3 PTHR24381:SF410 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000025524.2|UniProtKB=G3SC98 G3SC98 NCK1 PTHR19969:SF16 SH2-SH3 ADAPTOR PROTEIN-RELATED SH2_SH3 ADAPTER PROTEIN NCK1 receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of macromolecule metabolic process#GO:0060255;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;ephrin receptor signaling pathway#GO:0048013;regulation of intrinsic apoptotic signaling pathway#GO:2001242;cellular response to stimulus#GO:0051716;regulation of response to endoplasmic reticulum stress#GO:1905897;positive regulation of signal transduction#GO:0009967;positive regulation of translation#GO:0045727;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of apoptotic signaling pathway#GO:2001233;response to endoplasmic reticulum stress#GO:0034976;negative regulation of signal transduction#GO:0009968;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;positive regulation of apoptotic process#GO:0043065;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 T cell activation#P00053>nck#P01314;PDGF signaling pathway#P00047>Grb2#P01148;Angiogenesis#P00005>Nck#P00215;PDGF signaling pathway#P00047>Nck#P01147 GORGO|Ensembl=ENSGGOG00000003470.3|UniProtKB=G3QLQ0 G3QLQ0 AGR3 PTHR15337:SF5 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 3 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000040652.1|UniProtKB=A0A2I2ZVE3 A0A2I2ZVE3 LOC101140367 PTHR12015:SF103 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 4-LIKE chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515 response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular process#GO:0009987;taxis#GO:0042330;response to cytokine#GO:0034097;response to chemical#GO:0042221;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to peptide#GO:1901652;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954;regulation of cell motility#GO:2000145;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000039475.1|UniProtKB=A0A2I2YPM0 A0A2I2YPM0 PTHR11353:SF78 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;protein folding chaperone complex#GO:0101031;chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000011626.3|UniProtKB=G3R7K2 G3R7K2 GPS1 PTHR14145:SF2 26S PROTESOME SUBUNIT 6 COP9 SIGNALOSOME COMPLEX SUBUNIT 1 regulation of protein stability#GO:0031647;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000012470.3|UniProtKB=G3RZM4 G3RZM4 DPP8 PTHR11731:SF98 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 8 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000008596.3|UniProtKB=A0A2I2ZLR4 A0A2I2ZLR4 ANKRD27 PTHR24170:SF2 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 nervous system development#GO:0007399;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;endosomal transport#GO:0016197;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;cellular localization#GO:0051641;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;early endosome to late endosome transport#GO:0045022;neurogenesis#GO:0022008;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;intracellular transport#GO:0046907;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;localization within membrane#GO:0051668 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;late endosome#GO:0005770;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000043467.1|UniProtKB=A0A2I2ZVS8 A0A2I2ZVS8 RAD9B PTHR15237:SF2 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9B negative regulation of mitotic cell cycle#GO:0045930;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cellular response to stress#GO:0033554;regulation of cell cycle#GO:0051726;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to stimulus#GO:0050896;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;response to abiotic stimulus#GO:0009628;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;cellular response to abiotic stimulus#GO:0071214;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;response to radiation#GO:0009314;DNA integrity checkpoint signaling#GO:0031570 chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513 exodeoxyribonuclease#PC00098 GORGO|Ensembl=ENSGGOG00000025656.2|UniProtKB=G3RNN1 G3RNN1 NDUFB1 PTHR15222:SF4 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010339.3|UniProtKB=G3RYF3 G3RYF3 MTMR2 PTHR10807:SF42 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;lipid modification#GO:0030258;dephosphorylation#GO:0016311 membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000000149.3|UniProtKB=G3SCY2 G3SCY2 MANSC1 PTHR16021:SF7 MANSC DOMAIN CONTAINING PROTEIN 1 MANSC DOMAIN-CONTAINING PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000004639.3|UniProtKB=G3QPP4 G3QPP4 C18H16orf96 PTHR47080:SF1 CHROMOSOME 16 OPEN READING FRAME 96 DUF4795 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000002185.3|UniProtKB=A0A2I2ZGD2 A0A2I2ZGD2 WDR48 PTHR19862:SF14 WD REPEAT-CONTAINING PROTEIN 48 WD REPEAT-CONTAINING PROTEIN 48 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 GORGO|Ensembl=ENSGGOG00000037798.1|UniProtKB=A0A2I2ZMH2 A0A2I2ZMH2 MFSD9 PTHR23504:SF14 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 67 MEMBER A2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000042828.1|UniProtKB=A0A2I2Z530 A0A2I2Z530 PTHR11481:SF62 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 6 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000013865.3|UniProtKB=G3RDC7 G3RDC7 NT5DC3 PTHR12103:SF11 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphatase#PC00181;nucleotide phosphatase#PC00173;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000026382.2|UniProtKB=A0A2I2Z4F2 A0A2I2Z4F2 LOC101124746 PTHR11592:SF41 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 1 catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;response to stress#GO:0006950;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;catabolic process#GO:0009056;hydrogen peroxide metabolic process#GO:0042743;modified amino acid metabolic process#GO:0006575;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000011597.3|UniProtKB=G3R7H6 G3R7H6 STK40 PTHR22961:SF16 SER/THR PROTEIN KINASE-TRB SERINE_THREONINE-PROTEIN KINASE 40 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of MAPK cascade#GO:0043408 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000005941.3|UniProtKB=G3QT19 G3QT19 RAPGEF6 PTHR45161:SF4 CYTOSKELETON-ASSOCIATED PROTEIN 4 RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 ISOFORM X1 GORGO|Ensembl=ENSGGOG00000009675.3|UniProtKB=G3RT78 G3RT78 ZNF544 PTHR24381:SF394 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 544 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000014736.3|UniProtKB=G3RFL2 G3RFL2 PAPSS1 PTHR11055:SF17 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;ribose phosphate biosynthetic process#GO:0046390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 GORGO|Ensembl=ENSGGOG00000022717.2|UniProtKB=A0A2I2Y5N1 A0A2I2Y5N1 PTHR43612:SF5 TRIFUNCTIONAL ENZYME SUBUNIT ALPHA ENOYL-COA HYDRATASE intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000016885.3|UniProtKB=G3RL37 G3RL37 ZNF248 PTHR24377:SF262 IP01015P-RELATED GENE MODEL 1008, (NCBI) cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007608.3|UniProtKB=G3RQY8 G3RQY8 PLPPR5 PTHR10165:SF17 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 5 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cell communication#GO:0007154;dephosphorylation#GO:0016311;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258;signal transduction#GO:0007165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000037011.1|UniProtKB=A0A2I2ZTJ1 A0A2I2ZTJ1 LOC101143997 PTHR23236:SF123 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4B binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000007654.3|UniProtKB=G3RP55 G3RP55 FRYL PTHR12295:SF9 FURRY-RELATED PROTEIN FURRY HOMOLOG-LIKE cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell division site#GO:0032153 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006772.3|UniProtKB=G3QV62 G3QV62 TMEM201 PTHR28646:SF1 TRANSMEMBRANE PROTEIN 201 TRANSMEMBRANE PROTEIN 201 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;circulatory system development#GO:0072359;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;nuclear migration#GO:0007097;blood vessel morphogenesis#GO:0048514;system development#GO:0048731;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;organelle transport along microtubule#GO:0072384;tube development#GO:0035295;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;microtubule-based process#GO:0007017;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;multicellular organism development#GO:0007275;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907 nucleus#GO:0005634;organelle envelope#GO:0031967;membrane#GO:0016020;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000000951.3|UniProtKB=G3QF73 G3QF73 FBRS PTHR14429:SF24 FIBROSIN FAMILY MEMBER FIBROSIN GORGO|Ensembl=ENSGGOG00000015082.3|UniProtKB=G3RGH2 G3RGH2 BFSP1 PTHR14069:SF0 FILENSIN FILENSIN structural molecule activity#GO:0005198 visual system development#GO:0150063;cell development#GO:0048468;cell differentiation#GO:0030154;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;cellular process#GO:0009987;sensory system development#GO:0048880;epithelium development#GO:0060429;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000006451.3|UniProtKB=G3QUB4 G3QUB4 CNTROB PTHR34439:SF1 CENTROBIN CENTROBIN mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cell division#GO:0051301;centrosome cycle#GO:0007098;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic cytokinetic process#GO:1902410;microtubule cytoskeleton organization#GO:0000226;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinetic process#GO:0032506;centriole replication#GO:0007099;cytokinesis#GO:0000910;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005184.3|UniProtKB=A0A2I2YDZ2 A0A2I2YDZ2 PTHR10672:SF6 ADDUCIN BETA-ADDUCIN actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament depolymerization#GO:0030834;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840 postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000008658.3|UniProtKB=G3QZZ2 G3QZZ2 ESM1 PTHR15428:SF0 ENDOTHELIAL CELL-SPECIFIC MOLECULE 1 ESM-1 ENDOTHELIAL CELL-SPECIFIC MOLECULE 1 protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 system development#GO:0048731;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;regulation of cell communication#GO:0010646;circulatory system development#GO:0072359;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;positive regulation of signal transduction#GO:0009967;blood vessel morphogenesis#GO:0048514;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;tube development#GO:0035295;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 GORGO|Ensembl=ENSGGOG00000010534.3|UniProtKB=G3RUP8 G3RUP8 PTHR15141:SF7 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A2 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368 transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000012929.3|UniProtKB=A0A2I2ZHX6 A0A2I2ZHX6 MTAP PTHR42679:SF4 S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000674.3|UniProtKB=G3RX44 G3RX44 UBAP1 PTHR15960:SF2 LD44032P UBIQUITIN-ASSOCIATED PROTEIN 1 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000042638.1|UniProtKB=A0A2I2YRU9 A0A2I2YRU9 SNURF PTHR14508:SF2 SNRPN UPSTREAM READING FRAME PROTEIN, SNURF SNRPN UPSTREAM READING FRAME PROTEIN-RELATED organelle lumen#GO:0043233;nuclear speck#GO:0016607;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000024088.2|UniProtKB=G3RNS4 G3RNS4 SAMD4B PTHR12515:SF9 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG HOMOLOG 2 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000038655.1|UniProtKB=G3R411 G3R411 LOC101139737 PTHR26450:SF96 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52L1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014260.3|UniProtKB=G3S0T5 G3S0T5 SLC9B2 PTHR31102:SF14 FAMILY NOT NAMED SODIUM_HYDROGEN EXCHANGER 9B2 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000028357.2|UniProtKB=G3RZ95 G3RZ95 DCAF6 PTHR15574:SF39 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 6 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000000296.3|UniProtKB=G3QDH4 G3QDH4 PTHR15493:SF1 F-BOX ONLY PROTEIN 5 AND 43 F-BOX ONLY PROTEIN 43 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;cell cycle#GO:0007049;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;mitotic cell cycle phase transition#GO:0044772;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cell cycle G1/S phase transition#GO:0044843;regulation of reproductive process#GO:2000241;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;G1/S transition of mitotic cell cycle#GO:0000082;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000000884.3|UniProtKB=A4H235 A4H235 DEFB123 PTHR15001:SF3 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 123 cell killing#GO:0001906;immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000001965.3|UniProtKB=G3QHU8 G3QHU8 ZNF362 PTHR24381:SF401 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 384 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000003496.3|UniProtKB=G3QLS4 G3QLS4 GRIK1 PTHR18966:SF36 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 1 monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;signaling receptor activity#GO:0038023;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;potassium ion transmembrane transporter activity#GO:0015079;carboxylic acid transmembrane transporter activity#GO:0046943;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;sodium ion transmembrane transporter activity#GO:0015081;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987 asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;sodium channel complex#GO:0034706;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group I pathway#P00041>GluR5#P01054;Ionotropic glutamate receptor pathway#P00037>KA1#P01004;Ionotropic glutamate receptor pathway#P00037>KA#P01026 GORGO|Ensembl=ENSGGOG00000010690.3|UniProtKB=A0A2I2YD56 A0A2I2YD56 SLC23A1 PTHR11119:SF21 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 1 carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sugar transmembrane transporter activity#GO:0051119;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 carbohydrate transport#GO:0008643;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000001231.3|UniProtKB=A0A2I2YEZ4 A0A2I2YEZ4 NFE2L2 PTHR24411:SF3 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000002068.3|UniProtKB=A0A2I2ZB29 A0A2I2ZB29 HDGFL3 PTHR12550:SF84 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR-RELATED PROTEIN 3 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000015997.3|UniProtKB=A0A2I2Z7Z5 A0A2I2Z7Z5 ARHGAP32 PTHR15729:SF13 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 32 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;regulation of synapse assembly#GO:0051963;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular response to stimulus#GO:0051716;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse structure or activity#GO:0050803;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556 asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic specialization#GO:0099572;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;cell junction#GO:0030054;postsynaptic density#GO:0014069 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Gonadotropin-releasing hormone receptor pathway#P06664>RICS#G06882;Gonadotropin-releasing hormone receptor pathway#P06664>RICS#P06765;Gonadotropin-releasing hormone receptor pathway#P06664>RICS#G06669 GORGO|Ensembl=ENSGGOG00000014112.3|UniProtKB=G3RE17 G3RE17 ATXN2L PTHR12854:SF8 ATAXIN 2-RELATED ATAXIN-2-LIKE PROTEIN RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000002134.3|UniProtKB=G3QIA0 G3QIA0 PAPLN PTHR13723:SF281 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PAPILIN catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000013697.3|UniProtKB=A0A2I2Y434 A0A2I2Y434 CCDC6 PTHR15276:SF0 H4 D10S170 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 6 GORGO|Ensembl=ENSGGOG00000043045.1|UniProtKB=A0A2I2ZBE5 A0A2I2ZBE5 CEBPB PTHR23334:SF21 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000007837.3|UniProtKB=G3QXV1 G3QXV1 SULT1C4 PTHR11783:SF327 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1C4 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000015272.3|UniProtKB=G3RGY5 G3RGY5 CCDC43 PTHR31684:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 GORGO|Ensembl=ENSGGOG00000014875.3|UniProtKB=G3RFY0 G3RFY0 PTHR23285:SF8 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX3C RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004131.3|UniProtKB=G3QNE2 G3QNE2 STX7 PTHR19957:SF90 SYNTAXIN SYNTAXIN-7 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;vesicle fusion#GO:0006906 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane#GO:0016020 SNARE protein#PC00034 Parkinson disease#P00049>Syntaxin#P01215;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 GORGO|Ensembl=ENSGGOG00000010603.3|UniProtKB=G3S6F3 G3S6F3 RNF123 PTHR13363:SF5 RING FINGER AND SRY DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF123 ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000022684.2|UniProtKB=A0A2I2YEY7 A0A2I2YEY7 OR5P2 PTHR26452:SF90 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009353.3|UniProtKB=A0A2I2ZE90 A0A2I2ZE90 HAT1 PTHR12046:SF0 HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT N-acetyltransferase activity#GO:0008080;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010255.3|UniProtKB=G3R426 G3R426 ARHGEF17 PTHR12877:SF15 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 17 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000013623.3|UniProtKB=G3RCR8 G3RCR8 EPS15L1 PTHR11216:SF69 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15-LIKE 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;clathrin coat#GO:0030118;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000007111.3|UniProtKB=G3QW16 G3QW16 CPXM2 PTHR11532:SF45 PROTEASE M14 CARBOXYPEPTIDASE INACTIVE CARBOXYPEPTIDASE-LIKE PROTEIN X2 carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 GORGO|Ensembl=ENSGGOG00000011559.3|UniProtKB=G3R7E0 G3R7E0 HERPUD2 PTHR12943:SF5 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 2 PROTEIN cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000005366.3|UniProtKB=G3QRK5 G3QRK5 INTS11 PTHR11203:SF37 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER INTEGRATOR COMPLEX SUBUNIT 11 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540 RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000027934.2|UniProtKB=G3S9G1 G3S9G1 HSPA1L PTHR19375:SF210 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 1-LIKE pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;ribonucleoside triphosphate phosphatase activity#GO:0017111;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein refolding#GO:0042026;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 GORGO|Ensembl=ENSGGOG00000012216.3|UniProtKB=G3R938 G3R938 TMEM50A PTHR13180:SF4 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50A retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197 vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000023168.2|UniProtKB=G3SJD7 G3SJD7 HIKESHI PTHR12925:SF2 HIKESHI FAMILY MEMBER PROTEIN HIKESHI binding#GO:0005488;molecular carrier activity#GO:0140104;protein-folding chaperone binding#GO:0051087;nucleocytoplasmic carrier activity#GO:0140142;heat shock protein binding#GO:0031072;protein binding#GO:0005515;Hsp70 protein binding#GO:0030544 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000023488.2|UniProtKB=G3S1R5 G3S1R5 PTHR11952:SF4 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;nucleoside phosphate metabolic process#GO:0006753;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000010832.3|UniProtKB=A0A2I2Z6N8 A0A2I2Z6N8 UBE2D3 PTHR24068:SF543 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D3 aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein K11-linked ubiquitination#GO:0070979;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000012747.3|UniProtKB=G3RAG0 G3RAG0 SPINK14 PTHR47499:SF3 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 14 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000036529.1|UniProtKB=A0A2I2YTR7 A0A2I2YTR7 MRPL4 PTHR10746:SF18 50S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;post-transcriptional regulation of gene expression#GO:0010608;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;positive regulation of Notch signaling pathway#GO:0045747;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 GORGO|Gene=MT-ND5|UniProtKB=P03917 P03917 MT-ND5 PTHR42829:SF4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000003001.3|UniProtKB=A0A2I2YEU8 A0A2I2YEU8 GDPD1 PTHR42758:SF1 PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C LYSOPHOSPHOLIPASE D GDPD1 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 organophosphate catabolic process#GO:0046434;glycerolipid catabolic process#GO:0046503;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerophospholipid catabolic process#GO:0046475;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121;phospholipase#PC00186;lipase#PC00143 GORGO|Ensembl=ENSGGOG00000043212.1|UniProtKB=A0A2I2ZUM6 A0A2I2ZUM6 PTHR16004:SF5 RING FINGER PROTEIN 31-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF31 ubiquitin binding#GO:0043130;catalytic activity#GO:0003824;transferase activity#GO:0016740;polyubiquitin modification-dependent protein binding#GO:0031593;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;modification-dependent protein binding#GO:0140030;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000042777.1|UniProtKB=A0A2I2YB99 A0A2I2YB99 KLF9 PTHR23235:SF132 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 9 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011660.3|UniProtKB=G3R7M9 G3R7M9 NKX2-8 PTHR24340:SF27 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000015012.3|UniProtKB=G3RGB1 G3RGB1 ELOA PTHR15141:SF75 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000012882.3|UniProtKB=A0A2I2ZCV9 A0A2I2ZCV9 PTHR23045:SF21 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A LRRC37A_B LIKE PROTEIN 1 C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015983.3|UniProtKB=G3RBU1 G3RBU1 ZNF273 PTHR24381:SF355 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 682 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007633.3|UniProtKB=A0A2I2ZB54 A0A2I2ZB54 LOC101136913 PTHR26450:SF46 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000521.3|UniProtKB=G3QE28 G3QE28 KIF18A PTHR24115:SF399 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF18A macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515 protein-containing complex disassembly#GO:0032984;microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cell cycle#GO:0007049;supramolecular fiber organization#GO:0097435;cellular component disassembly#GO:0022411;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;organelle localization#GO:0051640;nuclear division#GO:0000280;protein depolymerization#GO:0051261;chromosome localization#GO:0050000;cytoskeleton organization#GO:0007010;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;microtubule#GO:0005874;spindle microtubule#GO:0005876;cytoplasmic microtubule#GO:0005881;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle#GO:0005819;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000023114.2|UniProtKB=G3SDK1 G3SDK1 OR8G1 PTHR48018:SF56 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8G1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006203.3|UniProtKB=G3QTP6 G3QTP6 NDST2 PTHR10605:SF53 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 2 transferase activity#GO:0016740;deacylase activity#GO:0160215;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;deacetylase activity#GO:0019213 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006282.3|UniProtKB=G3QTV8 G3QTV8 HOXC9 PTHR45970:SF1 AGAP004664-PA HOMEOBOX PROTEIN HOX-C9 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryo development#GO:0009790;anterior/posterior pattern specification#GO:0009952;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;skeletal system development#GO:0001501 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000008339.3|UniProtKB=G3QZ55 G3QZ55 TNPO3 PTHR12363:SF42 TRANSPORTIN 3 AND IMPORTIN 13 TRANSPORTIN-3 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013273.4|UniProtKB=G3RBT6 G3RBT6 FAF1 PTHR23322:SF96 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 1 transcription factor binding#GO:0008134;binding#GO:0005488;ubiquitin binding#GO:0043130;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 scaffold/adaptor protein#PC00226 FAS signaling pathway#P00020>FAF1#P00609 GORGO|Ensembl=ENSGGOG00000024090.2|UniProtKB=G3RVE7 G3RVE7 PIGC PTHR12982:SF1 PHOSPHATIDYLINOSITOL GLYCAN, CLASS C PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000012246.3|UniProtKB=G3R972 G3R972 RBM44 PTHR48026:SF8 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN RNA-BINDING PROTEIN 44 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000000476.3|UniProtKB=A0A2I2YQZ9 A0A2I2YQZ9 IL7 PTHR48492:SF1 INTERLEUKIN-7 INTERLEUKIN-7 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;signal transduction#GO:0007165;interleukin-7-mediated signaling pathway#GO:0038111;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Interleukin signaling pathway#P00036>Interleukin#P00970 GORGO|Ensembl=ENSGGOG00000002873.3|UniProtKB=G3QK63 G3QK63 ENPP2 PTHR10151:SF21 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE AUTOTAXIN glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;exonuclease activity#GO:0004527;binding#GO:0005488;metal ion binding#GO:0046872;nuclease activity#GO:0004518;zinc ion binding#GO:0008270;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;ion binding#GO:0043167;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid catabolic process#GO:0046475;organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000650.3|UniProtKB=A0A2I2YH98 A0A2I2YH98 NIBAN2 PTHR14392:SF2 NIBAN FAMILY MEMBER PROTEIN NIBAN 2 GORGO|Ensembl=ENSGGOG00000026015.2|UniProtKB=G3S2W2 G3S2W2 PTHR12138:SF156 PRIMATE-EXPANDED PROTEIN FAMILY LMO7 DOWNSTREAM NEIGHBOR PROTEIN GORGO|Ensembl=ENSGGOG00000000824.3|UniProtKB=G3QEV9 G3QEV9 OCRL PTHR11200:SF176 INOSITOL 5-PHOSPHATASE INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell projection#GO:0042995;membrane#GO:0016020;neuron projection#GO:0043005 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000009712.3|UniProtKB=G3R2M9 G3R2M9 LOC101146664 PTHR23222:SF32 PROHIBITIN PROHIBITIN mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007122.3|UniProtKB=G3QW21 G3QW21 NPRL2 PTHR12991:SF10 NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4 GATOR1 COMPLEX PROTEIN NPRL2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to nutrient levels#GO:0031667;response to stress#GO:0006950;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;negative regulation of response to stimulus#GO:0048585;negative regulation of TORC1 signaling#GO:1904262;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;Seh1-associated complex#GO:0035859;intracellular organelle#GO:0043229 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000005347.3|UniProtKB=G3RXE2 G3RXE2 HTRA3 PTHR22939:SF14 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA3 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;proteolysis#GO:0006508;protein metabolic process#GO:0019538;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;positive regulation of apoptotic process#GO:0043065 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000005129.3|UniProtKB=G3QQZ6 G3QQZ6 KREMEN2 PTHR24269:SF15 KREMEN PROTEIN KREMEN PROTEIN 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Kremen#P01463 GORGO|Ensembl=ENSGGOG00000009314.3|UniProtKB=G3S3Q5 G3S3Q5 PTHR13847:SF193 SARCOSINE DEHYDROGENASE-RELATED PYRUVATE DEHYDROGENASE PHOSPHATASE REGULATORY SUBUNIT, MITOCHONDRIAL mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000010401.3|UniProtKB=G3SAE8 G3SAE8 MED17 PTHR13114:SF7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036843.1|UniProtKB=A0A2I2ZFM1 A0A2I2ZFM1 PTHR11213:SF1 GLUCAGON-FAMILY NEUROPEPTIDE PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE signaling receptor binding#GO:0005102;binding#GO:0005488;hormone receptor binding#GO:0051427;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide hormone activity#GO:0005184;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;neuropeptide signaling pathway#GO:0007218;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein localization#GO:0032880;neuron development#GO:0048666;positive regulation of signaling#GO:0023056;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;nervous system development#GO:0007399;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408 perikaryon#GO:0043204;cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025 neuropeptide#PC00162 Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#G06667;Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#P06800;Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#G06879 GORGO|Ensembl=ENSGGOG00000000822.3|UniProtKB=G3QEV8 G3QEV8 ATP5IF1 PTHR23407:SF6 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ATPASE INHIBITOR, MITOCHONDRIAL molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;ligase activity#GO:0016874;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;enzyme binding#GO:0019899 pigment metabolic process#GO:0042440;cellular process#GO:0009987;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;metabolic process#GO:0008152;porphyrin-containing compound metabolic process#GO:0006778;developmental process#GO:0032502;pigment biosynthetic process#GO:0046148;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;heme biosynthetic process#GO:0006783;modified amino acid metabolic process#GO:0006575;folic acid-containing compound metabolic process#GO:0006760;myeloid cell differentiation#GO:0030099;pteridine-containing compound metabolic process#GO:0042558;cell differentiation#GO:0030154;tetrapyrrole biosynthetic process#GO:0033014;small molecule metabolic process#GO:0044281;cell development#GO:0048468;homeostatic process#GO:0042592;immune system process#GO:0002376;tetrapyrrole metabolic process#GO:0033013;tetrahydrofolate biosynthetic process#GO:0046654;homeostasis of number of cells#GO:0048872;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;porphyrin-containing compound biosynthetic process#GO:0006779;tetrahydrofolate metabolic process#GO:0046653 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000005851.3|UniProtKB=G3QST6 G3QST6 ANXA11 PTHR10502:SF29 ANNEXIN ANNEXIN A11 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;small molecule binding#GO:0036094;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488;ion binding#GO:0043167 phagocytosis#GO:0006909;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987;endocytosis#GO:0006897 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle#GO:0031982 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000006717.3|UniProtKB=G3QV11 G3QV11 NMUR2 PTHR24243:SF14 G-PROTEIN COUPLED RECEPTOR NEUROMEDIN-U RECEPTOR 2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000005372.3|UniProtKB=A4H225 A4H225 DEFB119 PTHR47902:SF1 BETA-DEFENSIN 119 BETA-DEFENSIN 119 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000009755.3|UniProtKB=A0A2I2Y7B0 A0A2I2Y7B0 RAB1B PTHR24073:SF1096 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1B GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;organelle assembly#GO:0070925;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000016876.3|UniProtKB=G3RL41 G3RL41 PRPF6 PTHR11246:SF1 PRE-MRNA SPLICING FACTOR PRE-MRNA-PROCESSING FACTOR 6 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;spliceosomal snRNP assembly#GO:0000387;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000000300.3|UniProtKB=G3QDH7 G3QDH7 SUSD6 PTHR46839:SF2 SUSHI DOMAIN-CONTAINING PROTEIN 6 SUSHI DOMAIN-CONTAINING PROTEIN 6 GORGO|Ensembl=ENSGGOG00000012402.3|UniProtKB=G3S917 G3S917 CIAPIN1 PTHR13273:SF17 ANAMORSIN ANAMORSIN cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009031.3|UniProtKB=G3R0Y2 G3R0Y2 OSTM1 PTHR15644:SF3 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 OSTEOPETROSIS-ASSOCIATED TRANSMEMBRANE PROTEIN 1 cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;osteoclast differentiation#GO:0030316;developmental process#GO:0032502;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;hemopoiesis#GO:0030097;leukocyte differentiation#GO:0002521;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000000159.3|UniProtKB=G3QD51 G3QD51 LOC101140376 PTHR47499:SF6 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 6 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000006859.3|UniProtKB=A0A2I2Y566 A0A2I2Y566 PIGX PTHR28650:SF1 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN GPI ALPHA-1,4-MANNOSYLTRANSFERASE I, STABILIZING SUBUNIT GORGO|Ensembl=ENSGGOG00000001516.3|UniProtKB=G3QGN5 G3QGN5 OLIG3 PTHR19290:SF96 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED OLIGODENDROCYTE TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000026837.2|UniProtKB=G3S4B8 G3S4B8 P2RX1 PTHR10125:SF9 P2X PURINOCEPTOR P2X PURINOCEPTOR 1 ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000009559.3|UniProtKB=G3R296 G3R296 PTHR24160:SF1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 53 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 53 chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of cell cycle process#GO:0010564;regulation of microtubule cytoskeleton organization#GO:0070507;chromosome localization#GO:0050000;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular component organization#GO:0051130;nuclear division#GO:0000280;regulation of cytokinesis#GO:0032465;regulation of microtubule polymerization#GO:0031113;positive regulation of organelle organization#GO:0010638;regulation of mitotic spindle organization#GO:0060236;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;mitotic cell cycle process#GO:1903047;regulation of microtubule polymerization or depolymerization#GO:0031110;chromosome organization#GO:0051276;positive regulation of cellular process#GO:0048522;regulation of mitotic cytokinesis#GO:1902412;mitotic sister chromatid segregation#GO:0000070;biological regulation#GO:0065007;positive regulation of protein polymerization#GO:0032273;organelle localization#GO:0051640;regulation of microtubule-based process#GO:0032886;regulation of cell division#GO:0051302;localization#GO:0051179;organelle fission#GO:0048285;mitotic metaphase chromosome alignment#GO:0007080;regulation of supramolecular fiber organization#GO:1902903;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of spindle organization#GO:0090224;regulation of cellular process#GO:0050794 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922 GORGO|Ensembl=ENSGGOG00000023769.2|UniProtKB=G3RSE0 G3RSE0 SUMO2 PTHR10562:SF131 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 2-RELATED protein binding#GO:0005515;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899 post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein sumoylation#GO:0016925;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 p53 pathway#P00059>Sumo-1 ligase#P04635 GORGO|Ensembl=ENSGGOG00000007488.3|UniProtKB=A0A2I2ZVS7 A0A2I2ZVS7 KCNAB1 PTHR43150:SF7 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-1 alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;molecular function regulator activity#GO:0098772;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;ion channel regulator activity#GO:0099106;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;protein binding#GO:0005515;channel regulator activity#GO:0016247;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;binding#GO:0005488;potassium channel regulator activity#GO:0015459;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108 regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of transmembrane transport#GO:0034762;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007 membrane#GO:0016020;main axon#GO:0044304;neuron projection#GO:0043005;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transporter complex#GO:1990351;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;transmembrane transporter complex#GO:1902495 GORGO|Ensembl=ENSGGOG00000001600.3|UniProtKB=G3QGW5 G3QGW5 ESPL1 PTHR12792:SF3 EXTRA SPINDLE POLES 1-RELATED SEPARIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;meiotic nuclear division#GO:0140013;chromosome separation#GO:0051304;cellular component organization or biogenesis#GO:0071840;meiotic chromosome segregation#GO:0045132;organelle organization#GO:0006996;cellular process#GO:0009987;nuclear division#GO:0000280;sexual reproduction#GO:0019953;organelle fission#GO:0048285;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;cell cycle process#GO:0022402;reproductive process#GO:0022414 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000000935.3|UniProtKB=A0A2I2ZPB2 A0A2I2ZPB2 SELP PTHR19325:SF484 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING P-SELECTIN carbohydrate binding#GO:0030246;oligosaccharide binding#GO:0070492;carbohydrate derivative binding#GO:0097367;organic acid binding#GO:0043177;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 response to peptide#GO:1901652;leukocyte migration#GO:0050900;immune system process#GO:0002376;cell adhesion#GO:0007155;cell migration#GO:0016477;cell motility#GO:0048870;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;leukocyte cell-cell adhesion#GO:0007159 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 complement component#PC00078;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000005332.3|UniProtKB=G3QRH1 G3QRH1 LOC101128115 PTHR12035:SF129 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 6 organic acid binding#GO:0043177;carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000016635.3|UniProtKB=G3RKG9 G3RKG9 PLAA PTHR19849:SF7 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN PHOSPHOLIPASE A-2-ACTIVATING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 process utilizing autophagic mechanism#GO:0061919;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of localization#GO:0032879;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;cellular process#GO:0009987;regulation of cell motility#GO:2000145;protein metabolic process#GO:0019538;inflammatory response#GO:0006954;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;positive regulation of locomotion#GO:0040017;defense response#GO:0006952;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of neuron migration#GO:2001222;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cell migration#GO:0030334;biological regulation#GO:0065007;macroautophagy#GO:0016236;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000016035.3|UniProtKB=G3RIX2 G3RIX2 ING4 PTHR10333:SF106 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 4 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of apoptotic process#GO:0042981 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000015717.3|UniProtKB=G3RI47 G3RI47 KCNC1 PTHR11537:SF87 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL KCNC1 transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;action potential#GO:0001508;metal ion transport#GO:0030001 postsynapse#GO:0098794;cell body#GO:0044297;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell leading edge#GO:0031252;presynapse#GO:0098793;neuron projection#GO:0043005;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;neuronal cell body#GO:0043025;neuron projection terminus#GO:0044306;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;presynaptic membrane#GO:0042734;voltage-gated potassium channel complex#GO:0008076;neuron projection membrane#GO:0032589;axon terminus#GO:0043679 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000014620.3|UniProtKB=G3RFA0 G3RFA0 SRSF7 PTHR23147:SF288 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 7 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear speck#GO:0016607;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000004965.4|UniProtKB=A0A2I2Y237 A0A2I2Y237 PIP4K2A PTHR23086:SF21 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 ALPHA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742 organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 kinase#PC00137;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000003997.3|UniProtKB=G3QN23 G3QN23 NOL6 PTHR17972:SF0 NUCLEOLAR RNA-ASSOCIATED PROTEIN NUCLEOLAR PROTEIN 6 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000044096.1|UniProtKB=A0A2I2YJ31 A0A2I2YJ31 PTHR31678:SF6 KERATIN-ASSOCIATED PROTEIN 6-3 KERATIN-ASSOCIATED PROTEIN 6-3 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000028012.2|UniProtKB=G3RQG3 G3RQG3 SLC4A1AP PTHR23308:SF66 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 KANADAPTIN molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000000466.4|UniProtKB=G3QDX6 G3QDX6 LOC101137932 PTHR10605:SF45 HEPARAN SULFATE SULFOTRANSFERASE N-HEPARAN SULFATE SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;deacetylase activity#GO:0019213;transferase activity#GO:0016740;catalytic activity#GO:0003824;deacylase activity#GO:0160215 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000015762.3|UniProtKB=A0A2I2Y7Y3 A0A2I2Y7Y3 CNOT7 PTHR10797:SF79 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;CCR4-NOT complex#GO:0030014;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;P-body#GO:0000932;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000040837.1|UniProtKB=A0A2I2ZBM9 A0A2I2ZBM9 PTHR11559:SF416 CARBOXYLESTERASE CARBOXYLESTERASE 3 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 esterase#PC00097 GORGO|Ensembl=ENSGGOG00000015828.3|UniProtKB=G3RID7 G3RID7 GFI1B PTHR24390:SF159 ZINC FINGER PROTEIN GROWTH FACTOR INDEPENDENT 1 TRANSCRIPTIONAL REPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000028505.3|UniProtKB=G3RQK4 G3RQK4 ZMYM1 PTHR45736:SF4 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 1 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000040468.1|UniProtKB=A0A2I2Z154 A0A2I2Z154 PTHR11627:SF59 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 aldolase#PC00044;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000002531.3|UniProtKB=G3QJA4 G3QJA4 OR2B3 PTHR26453:SF103 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B3-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043752.1|UniProtKB=A0A2I2Z2P0 A0A2I2Z2P0 CDC42 PTHR24072:SF337 RHO FAMILY GTPASE CELL DIVISION CONTROL PROTEIN 42 HOMOLOG heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;actin filament organization#GO:0007015;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;signaling#GO:0023052;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cell communication#GO:0007154;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349;p38 MAPK pathway#P05918>Cdc42#P06041;Axon guidance mediated by netrin#P00009>cdc42#P00364;T cell activation#P00053>cdc42#P01333;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Huntington disease#P00029>Rac#P00775;Ras Pathway#P04393>Cdc42#P04569;Integrin signalling pathway#P00034>Cdc42#P00938 GORGO|Ensembl=ENSGGOG00000026014.2|UniProtKB=G3SGF7 G3SGF7 CRYBA4 PTHR11818:SF19 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A4 structural molecule activity#GO:0005198 visual system development#GO:0150063;visual perception#GO:0007601;sensory perception of light stimulus#GO:0050953;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000036565.1|UniProtKB=A0A2I2ZCH8 A0A2I2ZCH8 PTHR11060:SF1 PROTEIN MEMO1 PROTEIN MEMO1 GORGO|Ensembl=ENSGGOG00000012166.3|UniProtKB=G3R8Z1 G3R8Z1 TACSTD2 PTHR14168:SF5 TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER 2 negative regulation of biological process#GO:0048519;cell-cell adhesion#GO:0098609;regulation of biological process#GO:0050789;cellular process#GO:0009987;negative regulation of cell adhesion#GO:0007162;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;cell adhesion#GO:0007155 anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;extracellular region#GO:0005576;apical junction complex#GO:0043296;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell-cell junction#GO:0005911;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000013280.3|UniProtKB=A0A2I2ZQ18 A0A2I2ZQ18 IQGAP1 PTHR14149:SF15 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP1 actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;cytoskeletal protein binding#GO:0008092;calmodulin binding#GO:0005516;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actomyosin contractile ring assembly#GO:0000915;signal transduction#GO:0007165;cellular process#GO:0009987;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;response to stimulus#GO:0050896;actomyosin structure organization#GO:0031032;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;actin filament organization#GO:0007015;mitotic cell cycle process#GO:1903047;cell migration#GO:0016477;epidermal growth factor receptor signaling pathway#GO:0007173;biological regulation#GO:0065007;ERBB signaling pathway#GO:0038127;cell communication#GO:0007154;cortical actin cytoskeleton organization#GO:0030866;enzyme-linked receptor protein signaling pathway#GO:0007167;mitotic cytokinetic process#GO:1902410;supramolecular fiber organization#GO:0097435;cortical cytoskeleton organization#GO:0030865;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;actin filament-based process#GO:0030029;mitotic cell cycle#GO:0000278;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;mitotic cytokinesis#GO:0000281;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;cell division#GO:0051301;cellular response to stimulus#GO:0051716 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000001312.3|UniProtKB=G3QG44 G3QG44 ESCO1 PTHR45884:SF1 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ESCO1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic sister chromatid cohesion#GO:0007064;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000011165.3|UniProtKB=G3R6D5 G3R6D5 TSPAN13 PTHR19282:SF203 TETRASPANIN TETRASPANIN-13 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005601.3|UniProtKB=G3QS59 G3QS59 CREB3L4 PTHR45996:SF2 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 4 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 GORGO|Ensembl=ENSGGOG00000002443.3|UniProtKB=G3RXT7 G3RXT7 TLR7 PTHR47410:SF2 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 7 signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;toll-like receptor signaling pathway#GO:0002224;defense response to virus#GO:0051607;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;regulation of response to biotic stimulus#GO:0002831;intracellular receptor signaling pathway#GO:0030522;response to external biotic stimulus#GO:0043207;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;response to virus#GO:0009615;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;positive regulation of gene expression#GO:0010628;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR#P01346 GORGO|Ensembl=ENSGGOG00000025456.2|UniProtKB=G3SFM7 G3SFM7 NOB1 PTHR12814:SF2 RNA-BINDING PROTEIN NOB1 RNA-BINDING PROTEIN NOB1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684 GORGO|Ensembl=ENSGGOG00000022028.2|UniProtKB=G3QS69 G3QS69 BEX2 PTHR19430:SF2 PROTEIN BEX1-RELATED PROTEIN BEX2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;cell communication#GO:0007154 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000039803.1|UniProtKB=A0A2I2Y7M7 A0A2I2Y7M7 CCNYL1 PTHR14248:SF32 CYCLIN Y, ISOFORM A CYCLIN-Y-LIKE PROTEIN 1 enzyme activator activity#GO:0008047;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 regulation of biological process#GO:0050789;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001828.3|UniProtKB=G3QHH2 G3QHH2 CCDC89 PTHR34768:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 89 COILED-COIL DOMAIN-CONTAINING PROTEIN 89 GORGO|Ensembl=ENSGGOG00000013979.3|UniProtKB=A0A2I2Z8Q3 A0A2I2Z8Q3 ALDOA PTHR11627:SF1 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE A carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332;lyase activity#GO:0016829 purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 lyase#PC00144;aldolase#PC00044 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 GORGO|Ensembl=ENSGGOG00000025353.2|UniProtKB=A0A2I2ZNK6 A0A2I2ZNK6 PTHR11799:SF17 PARAOXONASE SERUM PARAOXONASE_ARYLESTERASE 2 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to chemical#GO:0042221;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000005577.3|UniProtKB=G3QS39 G3QS39 SPP1 PTHR10607:SF1 OSTEOPONTIN OSTEOPONTIN cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 tissue development#GO:0009888;ossification#GO:0001503;multicellular organismal process#GO:0032501;cellular process#GO:0009987;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;biomineral tissue development#GO:0031214;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;bone mineralization#GO:0030282 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000043355.1|UniProtKB=A0A2I2YKW4 A0A2I2YKW4 RGS9BP PTHR21029:SF1 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G PROTEIN SIGNALING 9-BINDING PROTEIN detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;system process#GO:0003008;response to external stimulus#GO:0009605;sensory perception of light stimulus#GO:0050953;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;visual perception#GO:0007601;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 GORGO|Ensembl=ENSGGOG00000000157.3|UniProtKB=G3QD50 G3QD50 ADHFE1 PTHR11496:SF83 ALCOHOL DEHYDROGENASE HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000026835.2|UniProtKB=G3RTN7 G3RTN7 PTHR23267:SF325 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 5-37-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015773.3|UniProtKB=G3RRX3 G3RRX3 LOC101125118 PTHR32157:SF5 GENE 6268-RELATED CANCER_TESTIS ANTIGEN FAMILY 47 MEMBER B1 GORGO|Ensembl=ENSGGOG00000007655.3|UniProtKB=A0A2I2Z2D7 A0A2I2Z2D7 AFDN PTHR10398:SF2 AFADIN AFADIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal adaptor activity#GO:0008093 cell-cell junction organization#GO:0045216;cell adhesion#GO:0007155;cellular component organization or biogenesis#GO:0071840;cell-cell junction maintenance#GO:0045217;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell cortex#GO:0005938 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 Alzheimer disease-presenilin pathway#P00004>Afadin#P00146 GORGO|Ensembl=ENSGGOG00000014561.3|UniProtKB=G3RF44 G3RF44 FOXC2 PTHR11829:SF189 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN C2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000004312.3|UniProtKB=G3QNX1 G3QNX1 USP24 PTHR24006:SF729 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 24 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000004505.3|UniProtKB=G3QPC5 G3QPC5 MLLT3 PTHR47827:SF5 AHD DOMAIN-CONTAINING PROTEIN PROTEIN AF-9 binding#GO:0005488;chromatin binding#GO:0003682 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000015524.3|UniProtKB=G3RHM2 G3RHM2 VTA1 PTHR46009:SF1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport#GO:0045324;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000007047.3|UniProtKB=G3QVV7 G3QVV7 GNAI2 PTHR10218:SF73 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-2 ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled adenosine receptor signaling pathway#GO:0001973;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell surface receptor signaling pathway#GO:0007166;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;cell communication#GO:0007154 extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797 G-protein#PC00020;heterotrimeric G-protein#PC00117 Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;PI3 kinase pathway#P00048>Galpha#P01199;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid proenkephalin pathway#P05915>G-protein#P05994 GORGO|Ensembl=ENSGGOG00000005668.3|UniProtKB=G3QSC1 G3QSC1 PTHR23226:SF313 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 93 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013187.3|UniProtKB=G3RBK7 G3RBK7 SLC2A12 PTHR48023:SF2 D-XYLOSE-PROTON SYMPORTER-LIKE 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 12 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 anatomical structure development#GO:0048856;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;multicellular organism development#GO:0007275;localization#GO:0051179;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;transport#GO:0006810;developmental process#GO:0032502;carbohydrate transport#GO:0008643;multicellular organismal process#GO:0032501;carbohydrate transmembrane transport#GO:0034219;circulatory system development#GO:0072359;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000017010.3|UniProtKB=G3RLF5 G3RLF5 LRRC8A PTHR48051:SF3 FAMILY NOT NAMED VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8E cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000042011.1|UniProtKB=A0A2I2ZFF2 A0A2I2ZFF2 RNF227 PTHR22791:SF14 RING-TYPE DOMAIN-CONTAINING PROTEIN RING FINGER PROTEIN 227 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000038524.1|UniProtKB=A0A2I2ZMG2 A0A2I2ZMG2 HFM1 PTHR47835:SF3 HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG ATP-DEPENDENT DNA HELICASE HFM1-RELATED GORGO|Ensembl=ENSGGOG00000024702.2|UniProtKB=G3SGA8 G3SGA8 EIF4A1 PTHR24031:SF221 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A-I primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular protein-containing complex#GO:0140535;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000040789.1|UniProtKB=A0A2I2Z8T6 A0A2I2Z8T6 PTHR23001:SF24 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;protein binding#GO:0005515;RNA binding#GO:0003723;translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743;translation initiation factor binding#GO:0031369 cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;cytoplasmic translational initiation#GO:0002183;translational initiation#GO:0006413;translation#GO:0006412 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000008223.3|UniProtKB=G3S4X9 G3S4X9 RGS3 PTHR46848:SF1 REGULATOR OF G-PROTEIN SIGNALING 3 REGULATOR OF G PROTEIN SIGNALING 3 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 GORGO|Ensembl=ENSGGOG00000022115.2|UniProtKB=A0A2I2YIU1 A0A2I2YIU1 PTHR11158:SF23 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING PROTEIN 3A transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014 establishment of localization#GO:0051234;localization#GO:0051179;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000002461.3|UniProtKB=G3QJ41 G3QJ41 L3HYPDH PTHR33442:SF1 TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000001037.3|UniProtKB=A0A2I2ZT32 A0A2I2ZT32 PTHR23189:SF40 RNA RECOGNITION MOTIF-CONTAINING RNA-BINDING PROTEIN 15B-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004009.3|UniProtKB=G3QN33 G3QN33 ABCC12 PTHR24223:SF10 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 12 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000027171.2|UniProtKB=G3RSK8 G3RSK8 MRPL47 PTHR21183:SF18 RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000038152.1|UniProtKB=G3R079 G3R079 LOC101143949 PTHR23262:SF240 KERATIN ASSOCIATED PROTEIN KERATIN ASSOCIATED PROTEIN 9-7 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000021966.2|UniProtKB=A0A2I2ZH84 A0A2I2ZH84 MMP2 PTHR10201:SF29 MATRIX METALLOPROTEINASE 72 KDA TYPE IV COLLAGENASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;extracellular structure organization#GO:0043062;tissue remodeling#GO:0048771;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;cellular component organization#GO:0016043;response to hypoxia#GO:0001666;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;multicellular organismal process#GO:0032501;cellular process#GO:0009987;response to stress#GO:0006950 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000016731.3|UniProtKB=G3S2C6 G3S2C6 IP6K2 PTHR12400:SF47 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 phospholipid metabolic process#GO:0006644;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000034848.2|UniProtKB=G3SKT3 G3SKT3 FBXL13 PTHR13318:SF275 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 13 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000011969.3|UniProtKB=G3RNY0 G3RNY0 NUDT1 PTHR43758:SF2 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE OXIDIZED PURINE NUCLEOSIDE TRIPHOSPHATE HYDROLASE catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000022758.2|UniProtKB=G3SB09 G3SB09 FAM162A PTHR13674:SF2 GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN PROTEIN FAM162A positive regulation of organelle organization#GO:0010638;neuron apoptotic process#GO:0051402;regulation of release of cytochrome c from mitochondria#GO:0090199;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cellular response to hypoxia#GO:0071456;programmed cell death#GO:0012501;response to abiotic stimulus#GO:0009628;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;response to hypoxia#GO:0001666;response to chemical#GO:0042221;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000006084.3|UniProtKB=G3QTE0 G3QTE0 CDYL2 PTHR43684:SF2 FAMILY NOT NAMED CHROMODOMAIN Y-LIKE PROTEIN 2 intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;nucleus#GO:0005634;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000026040.2|UniProtKB=G3SG67 G3SG67 HTR1E PTHR24247:SF33 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1E transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000004748.3|UniProtKB=G3QQ20 G3QQ20 DNAH11 PTHR45703:SF12 DYNEIN HEAVY CHAIN DYNEIN AXONEMAL HEAVY CHAIN 11 microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000002802.3|UniProtKB=G3SC67 G3SC67 LOC101126892 PTHR12035:SF106 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 8 organic acid binding#GO:0043177;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;carbohydrate derivative binding#GO:0097367 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000008771.3|UniProtKB=G3R094 G3R094 INSL6 PTHR12004:SF1 RELAXIN INSULIN-LIKE PEPTIDE INSL6 peptide hormone#PC00179;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000028244.2|UniProtKB=G3RV06 G3RV06 ADH5 PTHR43880:SF4 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE CLASS-3 transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;cation binding#GO:0043169;metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022 metabolic process#GO:0008152;cellular response to oxygen-containing compound#GO:1901701;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;cellular detoxification of aldehyde#GO:0110095;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;response to toxic substance#GO:0009636 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000017055.3|UniProtKB=G3RLJ2 G3RLJ2 BTBD17 PTHR24410:SF12 HL07962P-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN 17 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014226.3|UniProtKB=A0A2I2Z1K0 A0A2I2Z1K0 PTHR15627:SF16 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015300.3|UniProtKB=G3RH11 G3RH11 PTGR2 PTHR43205:SF5 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 2 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;prostaglandin metabolic process#GO:0006693 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000036199.1|UniProtKB=A0A2I2YKA9 A0A2I2YKA9 ZNF681 PTHR24377:SF356 IP01015P-RELATED ZINC FINGER PROTEIN 681 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011077.3|UniProtKB=A0A2I2YLC9 A0A2I2YLC9 NQO2 PTHR10204:SF33 NAD P H OXIDOREDUCTASE-RELATED RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE] catalytic activity#GO:0003824;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity#GO:0016491 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000008429.3|UniProtKB=G3QZC5 G3QZC5 SYT8 PTHR10024:SF249 SYNAPTOTAGMIN SYNAPTOTAGMIN-8 SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299;protein binding#GO:0005515 transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of exocytosis#GO:0017157;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;regulation of localization#GO:0032879;exocytosis#GO:0006887;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;synaptic signaling#GO:0099536;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular component organization#GO:0051128;regulation of synaptic vesicle exocytosis#GO:2000300;export from cell#GO:0140352;signaling#GO:0023052 axon#GO:0030424;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular vesicle#GO:0097708;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 GORGO|Ensembl=ENSGGOG00000038222.1|UniProtKB=G3R9S1 G3R9S1 PTHR24027:SF78 CADHERIN-23 CADHERIN-LIKE PROTEIN 26 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell motility#GO:0048870;cell migration#GO:0016477;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 cadherin#PC00057;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000040133.1|UniProtKB=G3R1Z4 G3R1Z4 UBE2V1 PTHR48618:SF2 UBC CORE DOMAIN-CONTAINING PROTEIN UBIQUITIN CONJUGATING ENZYME E2 V1 GORGO|Ensembl=ENSGGOG00000011280.3|UniProtKB=G3R6N2 G3R6N2 DDN PTHR16757:SF1 DENDRIN DENDRIN GORGO|Ensembl=ENSGGOG00000009638.3|UniProtKB=G3R2G0 G3R2G0 CCS PTHR10003:SF86 SUPEROXIDE DISMUTASE CU-ZN -RELATED COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE molecular carrier activity#GO:0140104;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;antioxidant activity#GO:0016209;copper ion binding#GO:0005507;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;cellular process#GO:0009987;response to stress#GO:0006950;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000011489.3|UniProtKB=G3R774 G3R774 ANKUB1 PTHR46885:SF1 PROTEIN ANKUB1 PROTEIN ANKUB1 GORGO|Ensembl=ENSGGOG00000009576.3|UniProtKB=G3R2A8 G3R2A8 VIM PTHR45652:SF5 GLIAL FIBRILLARY ACIDIC PROTEIN VIMENTIN structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;axon#GO:0030424;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085;intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000024434.2|UniProtKB=G3SEF5 G3SEF5 FBXW7 PTHR22847:SF745 WD40 REPEAT PROTEIN F-BOX_WD REPEAT-CONTAINING PROTEIN 7 regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of nuclear division#GO:0051783;regulation of mitotic nuclear division#GO:0007088 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 Notch signaling pathway#P00045>Sel 10#P01102 GORGO|Ensembl=ENSGGOG00000002239.3|UniProtKB=G3SHW1 G3SHW1 BNIP1 PTHR12825:SF0 BNIP1-RELATED VESICLE TRANSPORT PROTEIN SEC20 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;membrane#GO:0016020;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000041949.1|UniProtKB=A0A2I2ZFB0 A0A2I2ZFB0 NME2 PTHR11349:SF116 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776 nucleoside triphosphate metabolic process#GO:0009141;biosynthetic process#GO:0009058;nucleoside triphosphate biosynthetic process#GO:0009142;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;cellular process#GO:0009987 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137;transferase#PC00220 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 GORGO|Ensembl=ENSGGOG00000014707.3|UniProtKB=A0A2I2ZX20 A0A2I2ZX20 TMEM141 PTHR47229:SF1 TRANSMEMBRANE PROTEIN 141 TRANSMEMBRANE PROTEIN 141 GORGO|Ensembl=ENSGGOG00000005625.3|UniProtKB=G3QS83 G3QS83 ANTXR1 PTHR16059:SF11 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000002323.3|UniProtKB=G3QIR9 G3QIR9 AGER PTHR11973:SF20 CELL SURFACE GLYCOPROTEIN MUC18-RELATED ADVANCED GLYCATION END PRODUCT-SPECIFIC RECEPTOR regulation of trans-synaptic signaling#GO:0099177;myeloid leukocyte activation#GO:0002274;nervous system development#GO:0007399;microglial cell activation#GO:0001774;response to stress#GO:0006950;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;neuron development#GO:0048666;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cellular developmental process#GO:0048869;macrophage activation#GO:0042116;neurogenesis#GO:0022008;defense response#GO:0006952;regulation of synaptic plasticity#GO:0048167;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;leukocyte activation#GO:0045321;anatomical structure development#GO:0048856;system development#GO:0048731;cell activation#GO:0001775;inflammatory response#GO:0006954 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000001168.3|UniProtKB=G3QFS0 G3QFS0 LOC101136730 PTHR26453:SF617 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2H2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007356.3|UniProtKB=G3QWP2 G3QWP2 GBA2 PTHR12654:SF33 BILE ACID BETA-GLUCOSIDASE-RELATED NON-LYSOSOMAL GLUCOSYLCERAMIDASE catalytic activity#GO:0003824;beta-glucosidase activity#GO:0008422;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501 hydrolase#PC00121;glucosidase#PC00108 GORGO|Ensembl=ENSGGOG00000005856.3|UniProtKB=G3QST8 G3QST8 DAB2 PTHR47695:SF5 PID DOMAIN-CONTAINING PROTEIN DISABLED HOMOLOG 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 localization#GO:0051179;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;transport#GO:0006810;regulation of response to stimulus#GO:0048583;positive regulation of developmental process#GO:0051094;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;positive regulation of cellular process#GO:0048522;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;positive regulation of endocytosis#GO:0045807;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;endocytosis#GO:0006897;regulation of cellular component organization#GO:0051128;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell differentiation#GO:0045597;regulation of endocytosis#GO:0030100;import into cell#GO:0098657;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;vesicle-mediated transport#GO:0016192;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;clathrin-coated pit#GO:0005905;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000016957.3|UniProtKB=G3RSF1 G3RSF1 ADAM33 PTHR11905:SF38 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 33 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000026538.2|UniProtKB=G3SCU5 G3SCU5 SLITRK4 PTHR45773:SF3 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 4 regulation of cell junction assembly#GO:1901888;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;regulation of synapse organization#GO:0050807;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell differentiation#GO:0030154;positive regulation of nervous system development#GO:0051962;cell morphogenesis#GO:0000902;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;cell morphogenesis involved in neuron differentiation#GO:0048667 cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cell junction#GO:0030054 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014822.3|UniProtKB=G3S7J1 G3S7J1 KIAA1217 PTHR22741:SF11 P140CAP/SNIP-RELATED SICKLE TAIL PROTEIN HOMOLOG cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Gene=MT-ND2|UniProtKB=Q9T9Y9 Q9T9Y9 MT-ND2 PTHR46552:SF1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;NADH dehydrogenase activity#GO:0003954;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651 mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000004936.3|UniProtKB=G3QQH2 G3QQH2 MAT2A PTHR11964:SF73 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 transferase#PC00220;nucleotidyltransferase#PC00174 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 GORGO|Ensembl=ENSGGOG00000007905.3|UniProtKB=G3QY10 G3QY10 PTHR12964:SF6 NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000023334.2|UniProtKB=G3SHZ6 G3SHZ6 PTHR45773:SF1 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 6 positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of cell junction assembly#GO:1901888;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;regulation of synapse organization#GO:0050807;neuron development#GO:0048666;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell morphogenesis#GO:0000902;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000023339.2|UniProtKB=G3S4G9 G3S4G9 DYNC2LI1 PTHR13236:SF0 DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2 CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;intraciliary transport involved in cilium assembly#GO:0035735;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cilium assembly#GO:0060271;cellular component organization#GO:0016043 catalytic complex#GO:1902494;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;dynein complex#GO:0030286;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000005754.3|UniProtKB=G3QSJ4 G3QSJ4 PRKRA PTHR46205:SF2 LOQUACIOUS, ISOFORM B INTERFERON-INDUCIBLE DOUBLE-STRANDED RNA-DEPENDENT PROTEIN KINASE ACTIVATOR A nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723 biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of metabolic process#GO:0009892;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of biological process#GO:0050789;siRNA processing#GO:0030422;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 Apoptosis signaling pathway#P00006>PACT#P00280 GORGO|Ensembl=ENSGGOG00000014734.3|UniProtKB=G3RFK7 G3RFK7 PHPT1 PTHR12258:SF10 JANUS-A/JANUS-B 14 KDA PHOSPHOHISTIDINE PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000010416.3|UniProtKB=G3R4F6 G3R4F6 B3GNT7 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;aminoglycan biosynthetic process#GO:0006023;glycoprotein biosynthetic process#GO:0009101;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004869.3|UniProtKB=G3QQA8 G3QQA8 MYL2 PTHR23049:SF9 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2, VENTRICULAR_CARDIAC MUSCLE ISOFORM protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092 system development#GO:0048731;cell fate commitment#GO:0045165;anatomical structure development#GO:0048856;cardiac muscle contraction#GO:0060048;animal gross anatomical part developmental process#GO:0160108;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;muscle structure development#GO:0061061;cell differentiation#GO:0030154;circulatory system development#GO:0072359;heart process#GO:0003015;muscle system process#GO:0003012;muscle cell differentiation#GO:0042692;heart contraction#GO:0060047;system process#GO:0003008;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell fate specification#GO:0001708;developmental process#GO:0032502;muscle contraction#GO:0006936;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;heart development#GO:0007507;cellular process#GO:0009987 myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;myosin complex#GO:0016459;contractile muscle fiber#GO:0043292 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000005387.3|UniProtKB=G3QRL6 G3QRL6 PTHR28562:SF3 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 GORGO|Ensembl=ENSGGOG00000005686.3|UniProtKB=G3QSE0 G3QSE0 ANPEP PTHR11533:SF172 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE N metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;blood circulation#GO:0008015;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;peptide catabolic process#GO:0043171;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;system process#GO:0003008;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;catabolic process#GO:0009056;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;proteolysis#GO:0006508;circulatory system process#GO:0003013 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000026597.2|UniProtKB=G3QL43 G3QL43 LOC101132076 PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED GORGO|Ensembl=ENSGGOG00000014910.3|UniProtKB=A0A2I2ZDH3 A0A2I2ZDH3 SLC4A10 PTHR11453:SF32 ANION EXCHANGE PROTEIN SODIUM-DRIVEN CHLORIDE BICARBONATE EXCHANGER secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000015943.3|UniProtKB=G3SIM4 G3SIM4 FNBP1L PTHR15735:SF14 FCH AND DOUBLE SH3 DOMAINS PROTEIN FORMIN-BINDING PROTEIN 1-LIKE plasma membrane organization#GO:0007009;localization#GO:0051179;cellular component organization#GO:0016043;clathrin-dependent endocytosis#GO:0072583;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970;transport#GO:0006810;membrane invagination#GO:0010324;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;regulation of actin cytoskeleton organization#GO:0032956;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000041604.1|UniProtKB=A0A2I2ZPW6 A0A2I2ZPW6 PTHR33768:SF7 MIP11318P CFAP97 DOMAIN CONTAINING 2 GORGO|Ensembl=ENSGGOG00000003150.3|UniProtKB=G3QKW6 G3QKW6 PAK1 PTHR45832:SF10 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE GORGO|Ensembl=ENSGGOG00000004591.3|UniProtKB=G3QPL2 G3QPL2 USP4 PTHR21646:SF45 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4 cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;regulation of protein stability#GO:0031647;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000022537.2|UniProtKB=A0A2I2ZER3 A0A2I2ZER3 PTHR26454:SF72 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C74 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013792.3|UniProtKB=G3RD58 G3RD58 SERTAD4 PTHR14272:SF4 SERTA DOMAIN-CONTAINING PROTEIN 4 SERTA DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000039543.1|UniProtKB=A0A2I2Y306 A0A2I2Y306 PTHR12138:SF158 PRIMATE-EXPANDED PROTEIN FAMILY SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000002663.3|UniProtKB=G3QJM4 G3QJM4 LRRC14B PTHR14224:SF27 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14B GORGO|Ensembl=ENSGGOG00000039054.1|UniProtKB=A0A2I2ZCS5 A0A2I2ZCS5 RHOV PTHR24072:SF144 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOV protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;cell communication#GO:0007154;localization#GO:0051179;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;response to stimulus#GO:0050896;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000005551.3|UniProtKB=G3QS18 G3QS18 HDX PTHR11636:SF80 POU DOMAIN HIGHLY DIVERGENT HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000039539.1|UniProtKB=A0A2I2ZG17 A0A2I2ZG17 LOC109025096 PTHR11467:SF182 HISTONE H1 HISTONE H1.0 chromatin DNA binding#GO:0031490;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;negative regulation of DNA recombination#GO:0045910;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000043246.1|UniProtKB=A0A2I2YZ99 A0A2I2YZ99 PYM1 PTHR22959:SF0 PYM PROTEIN PARTNER OF Y14 AND MAGO RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145 GORGO|Ensembl=ENSGGOG00000027293.2|UniProtKB=G3S4Q1 G3S4Q1 PTHR24055:SF109 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 11 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Ras Pathway#P04393>p38#P04558;Oxidative stress response#P00046>p38#P01135;p38 MAPK pathway#P05918>p38beta#P06029;FGF signaling pathway#P00021>p38#P00644;B cell activation#P00010>p38#P00384;TGF-beta signaling pathway#P00052>P38#P01275;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>p38#P00562;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955 GORGO|Ensembl=ENSGGOG00000012668.3|UniProtKB=G3RA93 G3RA93 PTHR19269:SF73 TROPOMYOSIN TROPOMYOSIN 3, RELATED SEQUENCE 7 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 muscle contraction#GO:0006936;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component organization#GO:0016043;muscle system process#GO:0003012;cellular process#GO:0009987;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000008571.3|UniProtKB=G3QZR1 G3QZR1 ETFRF1 PTHR21024:SF0 GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1 biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of metabolic process#GO:0019222;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000011415.3|UniProtKB=G3R707 G3R707 UROS PTHR12390:SF0 UROPORPHYRINOGEN III SYNTHASE UROPORPHYRINOGEN-III SYNTHASE catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;small molecule biosynthetic process#GO:0044283;porphyrin-containing compound biosynthetic process#GO:0006779;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;tetrapyrrole biosynthetic process#GO:0033014;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 Heme biosynthesis#P02746>Uroporphyrinogen-III synthase#P02974 GORGO|Ensembl=ENSGGOG00000015265.3|UniProtKB=A0A2I2ZRM3 A0A2I2ZRM3 RASSF5 PTHR22738:SF9 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 5 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013330.3|UniProtKB=G3RBY6 G3RBY6 NKAP PTHR13087:SF2 NF-KAPPA B ACTIVATING PROTEIN NF-KAPPA-B-ACTIVATING PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000036834.1|UniProtKB=A0A2I2ZL54 A0A2I2ZL54 PTHR10496:SF16 40S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN ES24 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025811.2|UniProtKB=G3SAK8 G3SAK8 SLC35G1 PTHR22911:SF138 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G1 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;export from cell#GO:0140352;homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013327.3|UniProtKB=G3RBY4 G3RBY4 CCDC34 PTHR23247:SF2 NY-REN-41 ANTIGEN L15 -RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 34 GORGO|Ensembl=ENSGGOG00000009010.3|UniProtKB=A0A2I2YKF5 A0A2I2YKF5 PTHR45644:SF24 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED OUTER MITOCHONDRIAL TRANSMEMBRANE HELIX TRANSLOCASE cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;localization within membrane#GO:0051668;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150 GORGO|Ensembl=ENSGGOG00000014449.3|UniProtKB=G3QWY9 G3QWY9 SLC7A2 PTHR43243:SF35 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 2 amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 amino acid transport#GO:0006865;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 GORGO|Ensembl=ENSGGOG00000023765.2|UniProtKB=A0A2I2Y8Z9 A0A2I2Y8Z9 PTHR47960:SF13 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 DEAD BOX PROTEIN 6 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 negative regulation of translation#GO:0017148;organelle assembly#GO:0070925;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;cytoplasmic stress granule assembly#GO:0034063;regulation of macromolecule metabolic process#GO:0060255;P-body assembly#GO:0033962;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;membraneless organelle assembly#GO:0140694;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000001926.3|UniProtKB=G3RU33 G3RU33 NOP2 PTHR22807:SF30 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;cellular process#GO:0009987;rRNA base methylation#GO:0070475;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000017140.3|UniProtKB=G3RLR8 G3RLR8 SPMIP8 PTHR35348:SF1 TESTIS, PROSTATE AND PLACENTA-EXPRESSED PROTEIN SPERM MICROTUBULE INNER PROTEIN 8 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;axonemal doublet microtubule#GO:0097545;supramolecular complex#GO:0099080;A axonemal microtubule#GO:0097649;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;microtubule#GO:0005874;cilium#GO:0005929;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015016.3|UniProtKB=A0A2I2Y7A6 A0A2I2Y7A6 CLN3 PTHR10981:SF0 BATTENIN BATTENIN microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041;regulation of biological quality#GO:0065008;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;intracellular monoatomic ion homeostasis#GO:0006873;cytosolic transport#GO:0016482;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;Golgi vesicle transport#GO:0048193;amino acid transport#GO:0006865;chemical homeostasis#GO:0048878;microtubule-based process#GO:0007017;import into cell#GO:0098657;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192;regulation of intracellular pH#GO:0051453;organelle localization#GO:0051640;regulation of pH#GO:0006885;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;homeostatic process#GO:0042592;microtubule-based movement#GO:0007018;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;cellular homeostasis#GO:0019725;vesicle cytoskeletal trafficking#GO:0099518;intracellular chemical homeostasis#GO:0055082;receptor-mediated endocytosis#GO:0006898;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle localization#GO:0051648;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705 Golgi apparatus#GO:0005794;lytic vacuole#GO:0000323;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000024671.2|UniProtKB=G3SK34 G3SK34 DEFB115 PTHR15001:SF9 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 115 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;cell killing#GO:0001906 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015392.3|UniProtKB=A0A2I2ZLJ1 A0A2I2ZLJ1 PDZD9 PTHR22698:SF1 PDZ DOMAIN-CONTAINING PROTEIN 9 PDZ DOMAIN-CONTAINING PROTEIN 9 GORGO|Ensembl=ENSGGOG00000016495.3|UniProtKB=A0A2I2ZVW4 A0A2I2ZVW4 NOVA1 PTHR10288:SF229 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN NOVA-1 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;animal gross anatomical part developmental process#GO:0160108;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nervous system development#GO:0007399;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;multicellular organism development#GO:0007275;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of mRNA splicing, via spliceosome#GO:0048024;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;RNA splicing, via transesterification reactions#GO:0000375;multicellular organismal process#GO:0032501;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;developmental process#GO:0032502 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036946.1|UniProtKB=G3RMN6 G3RMN6 LOC101131333 PTHR23262:SF203 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-9 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000012769.3|UniProtKB=G3RAH6 G3RAH6 FAM110A PTHR14758:SF4 AGAP005440-PA PROTEIN FAM110A GORGO|Ensembl=ENSGGOG00000028048.2|UniProtKB=G3S0Q5 G3S0Q5 RSU1 PTHR45752:SF156 LEUCINE-RICH REPEAT-CONTAINING RAS SUPPRESSOR PROTEIN 1 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009210.3|UniProtKB=G3R1E6 G3R1E6 KIF1C PTHR24115:SF322 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1C cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544 vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;axo-dendritic transport#GO:0008088;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle-mediated transport#GO:0016192;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;organelle localization#GO:0051640;axonal transport#GO:0098930;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;cytosolic transport#GO:0016482 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;axon#GO:0030424;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000042053.1|UniProtKB=G3S643 G3S643 SPTSSB PTHR28612:SF1 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;ceramide metabolic process#GO:0006672;cellular component organization or biogenesis#GO:0071840;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000040003.1|UniProtKB=A0A2I2ZUA4 A0A2I2ZUA4 B3GNT9 PTHR11214:SF91 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 9 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;aminoglycan biosynthetic process#GO:0006023 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000037594.1|UniProtKB=A0A2I2ZGA3 A0A2I2ZGA3 LOC101128279 PTHR48553:SF5 SMALL PROLINE-RICH PROTEIN 2E SMALL PROLINE-RICH PROTEIN 2A GORGO|Ensembl=ENSGGOG00000009852.3|UniProtKB=G3R307 G3R307 PMCH PTHR12091:SF0 MELANIN-CONCENTRATING HORMONE PRO-MCH protein binding#GO:0005515;neuropeptide receptor binding#GO:0071855;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 peptide hormone#PC00179;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000007383.3|UniProtKB=G3RS89 G3RS89 SLC43A2 PTHR20766:SF2 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171 neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002173.3|UniProtKB=G3S2L5 G3S2L5 CPLX1 PTHR16705:SF6 COMPLEXIN COMPLEXIN-1 protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of signaling#GO:0023051;export from cell#GO:0140352;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;exocytosis#GO:0006887;regulation of transport#GO:0051049;regulation of localization#GO:0032879;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;synaptic signaling#GO:0099536 axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;synapse#GO:0045202;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;terminal bouton#GO:0043195;cell projection#GO:0042995;neuron projection terminus#GO:0044306;cell junction#GO:0030054;axon terminus#GO:0043679;membrane#GO:0016020;neuron projection#GO:0043005;presynapse#GO:0098793;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000022769.2|UniProtKB=G3S5L0 G3S5L0 CISD1 PTHR13680:SF42 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;small molecule binding#GO:0036094;transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483;iron-sulfur cluster binding#GO:0051536 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 GORGO|Ensembl=ENSGGOG00000016834.3|UniProtKB=G3RKZ3 G3RKZ3 LIN37 PTHR31336:SF3 LIN37 HOMOLOG PROTEIN LIN-37 HOMOLOG negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013454.3|UniProtKB=G3RC97 G3RC97 ZNF671 PTHR24381:SF304 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 587B DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000012509.4|UniProtKB=A0A2I2YGG8 A0A2I2YGG8 ADAM23 PTHR11905:SF13 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 23 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000001908.3|UniProtKB=G3RT31 G3RT31 INSIG1 PTHR15301:SF11 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE 1 PROTEIN cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;negative regulation of intracellular signal transduction#GO:1902532;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;response to lipid#GO:0033993;response to chemical#GO:0042221;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;response to stress#GO:0006950;response to hormone#GO:0009725;metabolic process#GO:0008152;cellular response to peptide hormone stimulus#GO:0071375;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cellular response to nitrogen compound#GO:1901699;regulation of signal transduction#GO:0009966;macromolecule localization#GO:0033036;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;intracellular protein localization#GO:0008104;regulation of response to stress#GO:0080134;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;secondary alcohol metabolic process#GO:1902652;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular localization#GO:0051641;negative regulation of cell communication#GO:0010648;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to lipid#GO:0071396;cholesterol biosynthetic process#GO:0006695;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;alcohol biosynthetic process#GO:0046165;alcohol metabolic process#GO:0006066;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;negative regulation of response to stimulus#GO:0048585;lipid biosynthetic process#GO:0008610;SREBP signaling pathway#GO:0032933;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;biosynthetic process#GO:0009058;secondary alcohol biosynthetic process#GO:1902653;negative regulation of cellular process#GO:0048523;cellular response to insulin stimulus#GO:0032869;cholesterol metabolic process#GO:0008203;regulation of response to stimulus#GO:0048583 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 GORGO|Ensembl=ENSGGOG00000039791.1|UniProtKB=A0A2I2YXB3 A0A2I2YXB3 LOC101144244 PTHR31866:SF5 GENE 4779-RELATED SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000016279.3|UniProtKB=G3RJJ6 G3RJJ6 PADI2 PTHR10837:SF12 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE TYPE-2 catalytic activity#GO:0003824;histone modifying activity#GO:0140993;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000024602.2|UniProtKB=A0A2I2YZ40 A0A2I2YZ40 PTHR22426:SF5 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 SMALL ACIDIC PROTEIN-LIKE DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000005863.3|UniProtKB=G3QSU1 G3QSU1 ZNF821 PTHR24404:SF1 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 821 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000012214.3|UniProtKB=G3R940 G3R940 LOC101151086 PTHR12035:SF111 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 7 organic acid binding#GO:0043177;carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000009426.2|UniProtKB=A0A2I2Z8J9 A0A2I2Z8J9 PTHR26450:SF128 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002166.3|UniProtKB=G3QIC8 G3QIC8 CCNA2 PTHR10177:SF444 CYCLINS CYCLIN-A2 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402 intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 GORGO|Ensembl=ENSGGOG00000027213.2|UniProtKB=G3SGB0 G3SGB0 ZNF770 PTHR24408:SF34 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 48 transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000039382.1|UniProtKB=A0A2I2YUT7 A0A2I2YUT7 XKR5 PTHR16024:SF15 XK-RELATED PROTEIN XK-RELATED PROTEIN 5 plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;endocytosis#GO:0006897;cellular component organization#GO:0016043;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657;membrane invagination#GO:0010324;endomembrane system organization#GO:0010256;cellular process#GO:0009987;localization#GO:0051179;anatomical structure development#GO:0048856;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;programmed cell death#GO:0012501;cell death#GO:0008219;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;phagocytosis#GO:0006909;developmental process#GO:0032502;transport#GO:0006810;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000026986.2|UniProtKB=G3SC89 G3SC89 PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993 regulation of gene expression#GO:0010468;chromosome organization#GO:0051276;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;negative regulation of DNA-templated transcription#GO:0045892;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000023248.2|UniProtKB=G3RVN2 G3RVN2 GZF1 PTHR24381:SF302 ZINC FINGER PROTEIN GDNF-INDUCIBLE ZINC FINGER PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000042632.1|UniProtKB=A0A2I2YN56 A0A2I2YN56 TEX50 PTHR39232:SF1 TESTIS-EXPRESSED PROTEIN 50 TESTIS-EXPRESSED PROTEIN 50 GORGO|Ensembl=ENSGGOG00000026223.2|UniProtKB=G3S0M5 G3S0M5 LIPT1 PTHR12561:SF3 LIPOATE-PROTEIN LIGASE LIPOYL AMIDOTRANSFERASE LIPT1, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001789.3|UniProtKB=G3QHD5 G3QHD5 CKAP4 PTHR45161:SF1 CYTOSKELETON-ASSOCIATED PROTEIN 4 CYTOSKELETON-ASSOCIATED PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;rough endoplasmic reticulum#GO:0005791;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000005088.3|UniProtKB=G3QQW2 G3QQW2 PTHR21035:SF2 28S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS26 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000004539.3|UniProtKB=G3RM81 G3RM81 REXO5 PTHR12801:SF82 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 5 catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000043183.1|UniProtKB=G3RAV1 G3RAV1 PTHR12928:SF4 FRG1 PROTEIN FRG1 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000027512.2|UniProtKB=G3S7A2 G3S7A2 XPR1 PTHR10783:SF141 XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED SOLUTE CARRIER FAMILY 53 MEMBER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;phosphate transmembrane transporter activity#GO:0005315;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804;efflux transmembrane transporter activity#GO:0015562 cellular process#GO:0009987;phosphate ion transport#GO:0006817;homeostatic process#GO:0042592;export from cell#GO:0140352;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000000809.3|UniProtKB=G3RFH7 G3RFH7 PTHR11783:SF324 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1A2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010188.3|UniProtKB=G3R3W2 G3R3W2 NMT2 PTHR11377:SF14 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;localization within membrane#GO:0051668;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000028184.2|UniProtKB=G3S143 G3S143 PTHR10822:SF31 GLYPICAN GLYPICAN-6 cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell migration#GO:0016477;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell surface#GO:0009986;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007787.3|UniProtKB=G3RPZ0 G3RPZ0 RCBTB1 PTHR22872:SF4 BTK-BINDING PROTEIN-RELATED RCC1 AND BTB DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 GORGO|Ensembl=ENSGGOG00000009180.3|UniProtKB=A0A2I2ZXV5 A0A2I2ZXV5 SPAG7 PTHR13498:SF3 SPERM ASSOCIATED ANTIGEN 7 SPERM-ASSOCIATED ANTIGEN 7 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000037419.1|UniProtKB=A0A2I2ZMF8 A0A2I2ZMF8 LOC101123934 PTHR23503:SF99 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;transport#GO:0006810;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000005953.3|UniProtKB=G3QT22 G3QT22 ZFP42 PTHR14003:SF8 TRANSCRIPTIONAL REPRESSOR PROTEIN YY ZINC FINGER PROTEIN 42 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell development#GO:0048468;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;PcG protein complex#GO:0031519;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000027272.2|UniProtKB=G3RZM6 G3RZM6 NOPCHAP1 PTHR28674:SF1 SIMILAR TO DNA SEGMENT, CHR 10, WAYNE STATE UNIVERSITY 102,-EXPRESSED NOP PROTEIN CHAPERONE 1 binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 GORGO|Ensembl=ENSGGOG00000042445.1|UniProtKB=A0A2I2Y5C8 A0A2I2Y5C8 PICK1 PTHR12141:SF1 ARFAPTIN-RELATED PRKCA-BINDING PROTEIN molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular component organization or biogenesis#GO:0071840;regulation of endocytosis#GO:0030100;intracellular protein transport#GO:0006886;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of biological process#GO:0048518;dendritic spine organization#GO:0097061;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein transport#GO:0015031;cellular localization#GO:0051641;positive regulation of cellular component organization#GO:0051130;receptor clustering#GO:0043113;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;neuron projection organization#GO:0106027;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;regulation of actin nucleation#GO:0051125;intracellular transport#GO:0046907;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of endocytosis#GO:0045807;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;macromolecule localization#GO:0033036;localization#GO:0051179;localization within membrane#GO:0051668;synapse organization#GO:0050808;postsynapse organization#GO:0099173;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of supramolecular fiber organization#GO:1902903 organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;neuron to neuron synapse#GO:0098984;transport vesicle#GO:0030133;postsynaptic specialization#GO:0099572;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cell junction#GO:0030054;trans-Golgi network membrane#GO:0032588;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;organelle subcompartment#GO:0031984;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;postsynapse#GO:0098794;intracellular vesicle#GO:0097708 vesicle coat protein#PC00235 Ionotropic glutamate receptor pathway#P00037>PICK#P01012 GORGO|Ensembl=ENSGGOG00000011981.3|UniProtKB=G3R8I1 G3R8I1 TAOK2 PTHR47167:SF6 SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN SERINE_THREONINE-PROTEIN KINASE TAO2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000034975.2|UniProtKB=A0A2I2ZRK5 A0A2I2ZRK5 FAM217A PTHR22145:SF4 SI:CH211-266K22.6 PROTEIN FAM217A GORGO|Ensembl=ENSGGOG00000010211.3|UniProtKB=G3R3Y4 G3R3Y4 TBC1D17 PTHR22957:SF360 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 17 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000012160.3|UniProtKB=G3R8Y8 G3R8Y8 LOC101147376 PTHR14136:SF41 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 KHA DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000015438.3|UniProtKB=A0A2I2YWA2 A0A2I2YWA2 HRAS PTHR24070:SF465 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE HRAS hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 Ras Pathway#P04393>Ras#P04547;Gonadotropin-releasing hormone receptor pathway#P06664>Ras#P06753;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;EGF receptor signaling pathway#P00018>Ras#P00552;PDGF signaling pathway#P00047>Ras#P01154;VEGF signaling pathway#P00056>Ras#P01411;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;Integrin signalling pathway#P00034>Ras#P00916;Angiogenesis#P00005>Ras#P00238;B cell activation#P00010>Ras#P00376;T cell activation#P00053>Ras#P01306;p53 pathway feedback loops 2#P04398>Ras#P04651;FGF signaling pathway#P00021>Ras#P00633 GORGO|Ensembl=ENSGGOG00000039002.1|UniProtKB=A0A2I2ZJ84 A0A2I2ZJ84 VPS4A PTHR23074:SF83 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;localization#GO:0051179;cellular localization#GO:0051641;protein metabolic process#GO:0019538;vacuole organization#GO:0007033;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;metabolic process#GO:0008152;intracellular transport#GO:0046907;macromolecule catabolic process#GO:0009057;transport#GO:0006810;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endosomal transport#GO:0016197;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000004162.3|UniProtKB=G3QNH0 G3QNH0 GMPR PTHR43170:SF3 GMP REDUCTASE GMP REDUCTASE 1 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000008420.3|UniProtKB=G3QZC2 G3QZC2 HRC PTHR15054:SF3 HISTIDINE-RICH CALCIUM-BINDING PROTEIN-RELATED SARCOPLASMIC RETICULUM HISTIDINE-RICH CALCIUM-BINDING PROTEIN molecular sequestering activity#GO:0140313 monoatomic ion homeostasis#GO:0050801;regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;biological regulation#GO:0065007;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;regulation of system process#GO:0044057;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 GORGO|Ensembl=ENSGGOG00000004244.3|UniProtKB=G3QNP4 G3QNP4 AFG1L PTHR12169:SF6 ATPASE N2B AFG1-LIKE ATPASE hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000015296.3|UniProtKB=G3RMK9 G3RMK9 SRRM2 PTHR34755:SF3 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE_ARGININE REPETITIVE MATRIX PROTEIN 2 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 GORGO|Ensembl=ENSGGOG00000036819.1|UniProtKB=A0A2I2ZCQ1 A0A2I2ZCQ1 PTHR11753:SF12 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-3 COMPLEX SUBUNIT SIGMA-1 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000039046.1|UniProtKB=A0A2I2YNT4 A0A2I2YNT4 PTHR23095:SF49 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN MA6F transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000025911.2|UniProtKB=A0A2I2ZLD1 A0A2I2ZLD1 UGDH PTHR11374:SF59 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE UDP-GLUCOSE 6-DEHYDROGENASE biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000038556.1|UniProtKB=A0A2I2ZLP0 A0A2I2ZLP0 TMEM238L PTHR28613:SF2 SI:CH211-232M10.4-RELATED TRANSMEMBRANE PROTEIN 238-LIKE GORGO|Ensembl=ENSGGOG00000039418.1|UniProtKB=A0A2I2ZDR6 A0A2I2ZDR6 ZCWPW2 PTHR15999:SF6 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 2 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000013734.3|UniProtKB=G3RD03 G3RD03 EQTN PTHR36874:SF1 EQUATORIN EQUATORIN sexual reproduction#GO:0019953;secretion by cell#GO:0032940;multicellular organismal reproductive process#GO:0048609;localization#GO:0051179;secretion#GO:0046903;acrosome reaction#GO:0007340;export from cell#GO:0140352;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;endocytosis#GO:0006897;transport#GO:0006810;acrosomal vesicle exocytosis#GO:0060478;regulated exocytosis#GO:0045055;calcium-ion regulated exocytosis#GO:0017156;exocytosis#GO:0006887;establishment of localization#GO:0051234;import into cell#GO:0098657;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;cellular process#GO:0009987;single fertilization#GO:0007338;vesicle-mediated transport#GO:0016192 plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;acrosomal membrane#GO:0002080;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669 GORGO|Ensembl=ENSGGOG00000006936.3|UniProtKB=G3QVM1 G3QVM1 SP140 PTHR10417:SF9 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN SP140 NUCLEAR BODY PROTEIN nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007919.3|UniProtKB=A0A2I2Y3R1 A0A2I2Y3R1 TTN PTHR14340:SF13 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 TITIN cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;striated muscle tissue development#GO:0014706;cellular component assembly#GO:0022607;heart development#GO:0007507;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;circulatory system development#GO:0072359;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tissue development#GO:0009888;anatomical structure development#GO:0048856;system development#GO:0048731;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692 A band#GO:0031672;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;M band#GO:0031430;intracellular organelle#GO:0043229;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 GORGO|Ensembl=ENSGGOG00000024685.2|UniProtKB=G3SEU0 G3SEU0 HBZ PTHR11442:SF41 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ZETA tetrapyrrole binding#GO:0046906;binding#GO:0005488;molecular carrier activity#GO:0140104;heme binding#GO:0020037 transport#GO:0006810;developmental process#GO:0032502;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;cellular process#GO:0009987;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;localization#GO:0051179;cell development#GO:0048468;homeostatic process#GO:0042592;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 globin#PC00107;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000015036.4|UniProtKB=G3RGD9 G3RGD9 DENND5B PTHR46070:SF3 PINSTRIPE, ISOFORM A DENN DOMAIN-CONTAINING PROTEIN 5B enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 GORGO|Ensembl=ENSGGOG00000036904.1|UniProtKB=A0A2I2ZND1 A0A2I2ZND1 PTHR15887:SF3 TRANSMEMBRANE PROTEIN 69 TRANSMEMBRANE PROTEIN 69 GORGO|Ensembl=ENSGGOG00000043306.1|UniProtKB=A0A2I2Y8Y2 A0A2I2Y8Y2 PTHR24068:SF430 UBIQUITIN-CONJUGATING ENZYME E2 UBC CORE DOMAIN-CONTAINING PROTEIN acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000027226.2|UniProtKB=G3RR11 G3RR11 C9H11orf24 PTHR16021:SF9 MANSC DOMAIN CONTAINING PROTEIN 1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000016544.3|UniProtKB=G3RK82 G3RK82 SLC24A2 PTHR10846:SF41 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 2 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;antiporter activity#GO:0015297;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;regulation of synaptic plasticity#GO:0048167;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;monoatomic cation transport#GO:0006812;localization#GO:0051179;homeostatic process#GO:0042592;metal ion transport#GO:0030001;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;chemical homeostasis#GO:0048878;monoatomic cation transmembrane transport#GO:0098655;regulation of trans-synaptic signaling#GO:0099177;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;negative regulation of cell communication#GO:0010648;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;inorganic ion homeostasis#GO:0098771;negative regulation of signaling#GO:0023057;calcium ion homeostasis#GO:0055074;positive regulation of synaptic transmission#GO:0050806;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;negative regulation of biological process#GO:0048519;intracellular monoatomic ion homeostasis#GO:0006873 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000003854.3|UniProtKB=G3QMN9 G3QMN9 UCP2 PTHR45618:SF1 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED DICARBOXYLATE CARRIER SLC25A8 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 multicellular organismal process#GO:0032501;response to temperature stimulus#GO:0009266;response to stress#GO:0006950;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;multicellular organismal-level homeostasis#GO:0048871;temperature homeostasis#GO:0001659;intracellular transport#GO:0046907;transport#GO:0006810;response to cold#GO:0009409;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839;homeostatic process#GO:0042592;response to abiotic stimulus#GO:0009628;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;adaptive thermogenesis#GO:1990845 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000023259.2|UniProtKB=G3S475 G3S475 WASHC4 PTHR31409:SF0 WASH COMPLEX SUBUNIT 4 WASH COMPLEX SUBUNIT 4 intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000043506.1|UniProtKB=A0A2I2YKN8 A0A2I2YKN8 LOC109026304 PTHR23048:SF7 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 6 LIKE 2-RELATED polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;structural molecule activity#GO:0005198;isomerase activity#GO:0016853 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000002530.3|UniProtKB=G3QJA6 G3QJA6 PDZD8 PTHR21519:SF1 PDZ DOMAIN-CONTAINING PROTEIN 8 PDZ DOMAIN-CONTAINING PROTEIN 8 calcium ion homeostasis#GO:0055074;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592 mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane contact site#GO:0044232 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039561.1|UniProtKB=A0A2I2YL13 A0A2I2YL13 PTHR26450:SF72 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001918.3|UniProtKB=G3QHQ8 G3QHQ8 LRCH2 PTHR48051:SF14 FAMILY NOT NAMED LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 2 ISOFORM X1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004676.3|UniProtKB=G3QPS8 G3QPS8 MC2R PTHR22750:SF3 G-PROTEIN COUPLED RECEPTOR ADRENOCORTICOTROPIC HORMONE RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000005537.3|UniProtKB=G3QS07 G3QS07 CALCOCO2 PTHR31915:SF4 SKICH DOMAIN-CONTAINING PROTEIN CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 catabolic process#GO:0009056;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of autophagosome maturation#GO:1901096;positive regulation of catabolic process#GO:0009896;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;macroautophagy#GO:0016236;response to other organism#GO:0051707;positive regulation of cellular component organization#GO:0051130;positive regulation of metabolic process#GO:0009893;positive regulation of organelle organization#GO:0010638;process utilizing autophagic mechanism#GO:0061919;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of macroautophagy#GO:0016239;metabolic process#GO:0008152;regulation of macroautophagy#GO:0016241;response to biotic stimulus#GO:0009607;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;autophagy#GO:0006914;cellular process#GO:0009987;defense response to other organism#GO:0098542 membraneless organelle#GO:0043228;nuclear body#GO:0016604;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000023463.2|UniProtKB=G3S461 G3S461 UBFD1 PTHR16470:SF0 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 GORGO|Ensembl=ENSGGOG00000004132.3|UniProtKB=A0A2I2Y8P5 A0A2I2Y8P5 PTHR13680:SF36 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 IRON SULPHUR DOMAIN-CONTAINING PROTEIN transaminase activity#GO:0008483;transferase activity#GO:0016740;binding#GO:0005488;small molecule binding#GO:0036094;catalytic activity#GO:0003824;iron-sulfur cluster binding#GO:0051536 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008216.3|UniProtKB=G3RVS4 G3RVS4 LOC101128930 PTHR11801:SF39 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5B transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to endogenous stimulus#GO:0009719;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cell surface receptor signaling pathway via STAT#GO:0097696;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;response to hormone#GO:0009725;cell surface receptor signaling pathway#GO:0007166;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cytokine-mediated signaling pathway#GO:0019221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway via JAK-STAT#GO:0007259 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;JAK/STAT signaling pathway#P00038>STAT#P01027 GORGO|Ensembl=ENSGGOG00000044109.1|UniProtKB=G3RQE2 G3RQE2 LOC109026182 PTHR26452:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H6 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000011501.3|UniProtKB=G3R786 G3R786 RRAGB PTHR11259:SF4 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN B nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;negative regulation of autophagy#GO:0010507;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;positive regulation of TOR signaling#GO:0032008;negative regulation of catabolic process#GO:0009895;response to stress#GO:0006950;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000010750.3|UniProtKB=G3S7C4 G3S7C4 GATD1 PTHR48094:SF18 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 1 GORGO|Gene=WNT7A|UniProtKB=Q1KYK7 Q1KYK7 WNT7A PTHR12027:SF78 WNT RELATED PROTEIN WNT-7A G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;Wnt signaling pathway#GO:0016055;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;positive regulation of signaling#GO:0023056;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;regulation of JNK cascade#GO:0046328;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;nervous system development#GO:0007399 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 GORGO|Ensembl=ENSGGOG00000003732.3|UniProtKB=G3QMD1 G3QMD1 TOMM70 PTHR46208:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000003111.3|UniProtKB=G3RSR5 G3RSR5 PRSS50 PTHR24253:SF35 TRANSMEMBRANE PROTEASE SERINE THREONINE PROTEASE PRSS50-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006587.3|UniProtKB=A0A2I2Z1K6 A0A2I2Z1K6 RBM41 PTHR16105:SF2 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING PROTEIN 41 GORGO|Ensembl=ENSGGOG00000024785.2|UniProtKB=G3RV23 G3RV23 LOC115931590 PTHR23226:SF138 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5A-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012322.3|UniProtKB=G3R9E4 G3R9E4 DONSON PTHR12972:SF0 DOWNSTREAM NEIGHBOR OF SON PROTEIN DOWNSTREAM NEIGHBOR OF SON cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000040922.1|UniProtKB=A0A2I2Y916 A0A2I2Y916 NUDT16 PTHR31699:SF5 NUDIX T16 FAMILY MEMBER U8 SNORNA-DECAPPING ENZYME hydrolase activity, acting on ester bonds#GO:0016788;snoRNA binding#GO:0030515;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;RNA binding#GO:0003723;hydrolase activity#GO:0016787 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000044070.1|UniProtKB=A0A2I2Z4N0 A0A2I2Z4N0 TPRG1 PTHR31108:SF6 TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN TUMOR PROTEIN P63-REGULATED GENE 1 PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000026173.2|UniProtKB=A0A2I2ZGU9 A0A2I2ZGU9 PTHR12146:SF10 40S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN ES10 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000002707.3|UniProtKB=G3QJR7 G3QJR7 SPON2 PTHR11311:SF15 SPONDIN SPONDIN-2 cellular process#GO:0009987;cell adhesion#GO:0007155 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000007386.3|UniProtKB=G3QWR3 G3QWR3 CNST PTHR28581:SF1 CONSORTIN CONSORTIN protein binding#GO:0005515;binding#GO:0005488 regulation of transport#GO:0051049;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;biological regulation#GO:0065007;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of vesicle-mediated transport#GO:0060627;regulation of protein localization to membrane#GO:1905475;positive regulation of cellular process#GO:0048522 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;transport vesicle#GO:0030133;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000043922.1|UniProtKB=A0A2I2YDK9 A0A2I2YDK9 NRAS PTHR24070:SF189 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE NRAS hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;Ras protein signal transduction#GO:0007265;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Ras Pathway#P04393>Ras#P04547;Integrin signalling pathway#P00034>Ras#P00916;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;PI3 kinase pathway#P00048>Ras#P01182;B cell activation#P00010>Ras#P00376;Angiogenesis#P00005>Ras#P00238;p53 pathway feedback loops 2#P04398>Ras#P04651;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;FGF signaling pathway#P00021>Ras#P00633;Interleukin signaling pathway#P00036>Ras#P00977;T cell activation#P00053>Ras#P01306 GORGO|Ensembl=ENSGGOG00000009790.3|UniProtKB=G3RRQ8 G3RRQ8 AXL PTHR24416:SF323 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR UFO catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;endocytosis#GO:0006897;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;wound healing#GO:0042060;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;lymphocyte activation#GO:0046649;nervous system development#GO:0007399;multicellular organism development#GO:0007275;hemostasis#GO:0007599;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;transport#GO:0006810;blood coagulation#GO:0007596;leukocyte differentiation#GO:0002521;regulation of programmed cell death#GO:0043067;mononuclear cell differentiation#GO:1903131;regulation of body fluid levels#GO:0050878;cell differentiation#GO:0030154;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;response to stress#GO:0006950;coagulation#GO:0050817;cell surface receptor signaling pathway#GO:0007166;natural killer cell activation#GO:0030101;regulation of apoptotic process#GO:0042981;import into cell#GO:0098657;leukocyte activation#GO:0045321;positive regulation of cell communication#GO:0010647;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;localization#GO:0051179;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;system development#GO:0048731;response to wounding#GO:0009611;cell migration#GO:0016477;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;hemopoiesis#GO:0030097;phagocytosis#GO:0006909;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;platelet activation#GO:0030168 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014400.3|UniProtKB=G3REQ3 G3REQ3 RNF2 PTHR46076:SF4 E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RING2 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;chromatin binding#GO:0003682;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;PcG protein complex#GO:0031519;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000001568.3|UniProtKB=G3QGT5 G3QGT5 PRMT7 PTHR11006:SF4 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 7 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;histone modifying activity#GO:0140993;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016888.3|UniProtKB=A0A2I2ZT88 A0A2I2ZT88 PTHR13385:SF4 AUTOPHAGY PROTEIN 12 UBIQUITIN-LIKE PROTEIN ATG12 aminoacyltransferase activity#GO:0016755;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component disassembly#GO:0022411;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;polysaccharide catabolic process#GO:0000272;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;carbohydrate metabolic process#GO:0005975;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977 membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;autophagosome#GO:0005776;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000044137.1|UniProtKB=A0A2I2YG30 A0A2I2YG30 LOC129528915 PTHR48001:SF155 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7A2-RELATED transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004551.3|UniProtKB=G3QPH0 G3QPH0 ITPK1 PTHR14217:SF25 INOSITOL-TETRAKISPHOSPHATE 1-KINASE INOSITOL-TETRAKISPHOSPHATE 1-KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000037572.1|UniProtKB=A0A2I2YWV8 A0A2I2YWV8 TEAD1 PTHR11834:SF4 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;hippo signaling#GO:0035329;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000039874.1|UniProtKB=A0A2I2YES5 A0A2I2YES5 PTHR12300:SF33 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 1 signaling receptor binding#GO:0005102;binding#GO:0005488;microtubule binding#GO:0008017;G protein-coupled receptor binding#GO:0001664;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987 endoplasmic reticulum#GO:0005783;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;endoplasmic reticulum tubular network#GO:0071782;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;cytoplasmic microtubule#GO:0005881;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000026079.2|UniProtKB=G3RYM5 G3RYM5 SLK PTHR46538:SF1 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE GORGO|Ensembl=ENSGGOG00000000129.3|UniProtKB=G3QD24 G3QD24 TMEM147 PTHR12869:SF0 SMALL SEVEN TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN BOS COMPLEX SUBUNIT TMEM147 GORGO|Ensembl=ENSGGOG00000024737.2|UniProtKB=A0A2I2Y3L9 A0A2I2Y3L9 AKAP12 PTHR23209:SF4 A-KINASE ANCHOR PROTEIN 12 A-KINASE ANCHOR PROTEIN 12 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004417.2|UniProtKB=G3QP46 G3QP46 TMEM240 PTHR28666:SF1 TRANSMEMBRANE PROTEIN 240 TRANSMEMBRANE PROTEIN 240 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic membrane#GO:0097060;cell junction#GO:0030054 GORGO|Ensembl=ENSGGOG00000012962.3|UniProtKB=A0A2I2ZD51 A0A2I2ZD51 SRPRA PTHR43134:SF1 SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 establishment of protein localization#GO:0045184;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of localization#GO:0051234;protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting to ER#GO:0045047 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein-binding activity modulator#PC00095;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000015391.3|UniProtKB=A0A2I2ZFS3 A0A2I2ZFS3 EIF2A PTHR13227:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2A EUKARYOTIC TRANSLATION INITIATION FACTOR 2A translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2A#P06762 GORGO|Ensembl=ENSGGOG00000010478.3|UniProtKB=G3S4S6 G3S4S6 PTHR48026:SF2 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000012892.3|UniProtKB=G3RAU5 G3RAU5 BRF2 PTHR11618:SF5 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION FACTOR IIIB 50 KDA SUBUNIT protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 General transcription regulation#P00023>TFIIB#P00668;Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397 GORGO|Ensembl=ENSGGOG00000024932.2|UniProtKB=A0A2I2Z4V5 A0A2I2Z4V5 ZBTB42 PTHR24394:SF20 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 42 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006915.3|UniProtKB=G3QVJ7 G3QVJ7 CDH20 PTHR24027:SF84 CADHERIN-23 CADHERIN-20 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell migration#GO:0016477;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;cell motility#GO:0048870;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000002298.3|UniProtKB=G3QIP6 G3QIP6 PEX16 PTHR13299:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX16 PEROXISOMAL MEMBRANE PROTEIN PEX16 cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;peroxisome organization#GO:0007031;cellular component organization#GO:0016043;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000012522.3|UniProtKB=G3R9Y8 G3R9Y8 DYNC2H1 PTHR45703:SF22 DYNEIN HEAVY CHAIN CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000043330.1|UniProtKB=A0A2I2ZAP9 A0A2I2ZAP9 PTHR12430:SF3 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;intracellular transport#GO:0046907;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;mitochondrial transport#GO:0006839;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;localization#GO:0051179;nucleic acid transport#GO:0050657;transmembrane transport#GO:0055085;cellular localization#GO:0051641;mitochondrial transmembrane transport#GO:1990542 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane translocase complex#GO:0005742 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013977.3|UniProtKB=G3SCQ3 G3SCQ3 PYCR1 PTHR11645:SF6 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE 1, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283 reductase#PC00198;metabolite interconversion enzyme#PC00262 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 GORGO|Ensembl=ENSGGOG00000001505.3|UniProtKB=G3QGM6 G3QGM6 TRIP6 PTHR24212:SF7 ZYXIN/TRIP6 THYROID RECEPTOR-INTERACTING PROTEIN 6 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646 intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;organelle#GO:0043226;stress fiber#GO:0001725;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;actomyosin#GO:0042641;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000003455.3|UniProtKB=G3QLP1 G3QLP1 CR2 PTHR19325:SF391 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT RECEPTOR TYPE 2 regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;immune response#GO:0006955;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;adaptive immune response#GO:0002250;negative regulation of response to stimulus#GO:0048585;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;T cell mediated immunity#GO:0002456;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;regulation of immune effector process#GO:0002697;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 defense/immunity protein#PC00090;complement component#PC00078 GORGO|Ensembl=ENSGGOG00000042090.1|UniProtKB=A0A2I2YHN6 A0A2I2YHN6 LOC101151107 PTHR21017:SF18 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 3B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;mitophagy#GO:0000423;process utilizing autophagic mechanism#GO:0061919;autophagy#GO:0006914;cellular process#GO:0009987;catabolic process#GO:0009056;macroautophagy#GO:0016236 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000025276.2|UniProtKB=G3S0S7 G3S0S7 ADCY5 PTHR45627:SF7 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 5 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;ribose phosphate biosynthetic process#GO:0046390;cyclic purine nucleotide metabolic process#GO:0052652;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 adenylate cyclase#PC00043 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;GABA-B receptor II signaling#P05731>AC#P05760;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 GORGO|Ensembl=ENSGGOG00000000096.3|UniProtKB=G3SJ37 G3SJ37 KLF4 PTHR23235:SF117 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 CCKR signaling map#P06959>KLF4#P07227 GORGO|Ensembl=ENSGGOG00000007485.3|UniProtKB=G3QWZ8 G3QWZ8 CIROZ PTHR38653:SF1 GENE 572-RELATED CILIATED LEFT-RIGHT ORGANIZER ZP-N DOMAINS-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000037586.1|UniProtKB=A0A2I2ZT56 A0A2I2ZT56 PTHR24341:SF8 HOMEOBOX PROTEIN ENGRAILED CYTOPLASMIC POLYADENYLATED HOMEOBOX-LIKE PROTEIN 2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000024115.2|UniProtKB=G3SDU6 G3SDU6 LOC101125865 PTHR26453:SF117 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2C3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004340.3|UniProtKB=G3QNX7 G3QNX7 CIB3 PTHR45791:SF7 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 3 metal ion binding#GO:0046872;magnesium ion binding#GO:0000287;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion homeostasis#GO:0050801 GORGO|Ensembl=ENSGGOG00000036688.1|UniProtKB=A0A2I2ZJN6 A0A2I2ZJN6 HOXB9 PTHR45970:SF5 AGAP004664-PA HOMEOBOX PROTEIN HOX-B9 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;skeletal system development#GO:0001501;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;anterior/posterior pattern specification#GO:0009952;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;embryo development#GO:0009790 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000002532.3|UniProtKB=G3QJA7 G3QJA7 PINLYP PTHR20914:SF50 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 PHOSPHOLIPASE A2 INHIBITOR AND LY6_PLAUR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000034966.2|UniProtKB=G3SKN2 G3SKN2 SLC18A3 PTHR23506:SF13 GH10249P VESICULAR ACETYLCHOLINE TRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 clathrin vesicle coat#GO:0030125;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated endocytic vesicle#GO:0045334;presynapse#GO:0098793;neuron projection#GO:0043005;vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;endocytic vesicle#GO:0030139;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;axon terminus#GO:0043679;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;AP-1 adaptor complex#GO:0030121;axon#GO:0030424;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;neuron projection terminus#GO:0044306;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025 secondary carrier transporter#PC00258;transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>VAChT#P01065;Nicotinic acetylcholine receptor signaling pathway#P00044>VAChT#P01089;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>VAChT#P01078 GORGO|Ensembl=ENSGGOG00000007822.3|UniProtKB=G3QXT6 G3QXT6 INSYN2B PTHR28682:SF2 INHIBITORY SYNAPTIC FACTOR 2A-RELATED PROTEIN INSYN2B GORGO|Ensembl=ENSGGOG00000002599.3|UniProtKB=G3QJG6 G3QJG6 MYRIP PTHR14555:SF6 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED RAB EFFECTOR MYRIP protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;myosin binding#GO:0017022 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232 myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000003091.3|UniProtKB=A0A2I2Z6E0 A0A2I2Z6E0 CLNS1A PTHR21399:SF3 CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN METHYLOSOME SUBUNIT PICLN nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;spliceosomal snRNP assembly#GO:0000387;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607 nucleus#GO:0005634;cytosol#GO:0005829;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013955.3|UniProtKB=G3S4N9 G3S4N9 NANOG PTHR24327:SF79 HOMEOBOX PROTEIN HOMEOBOX PROTEIN NANOG-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;stem cell population maintenance#GO:0019827;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;maintenance of cell number#GO:0098727;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000013648.3|UniProtKB=G3RXQ6 G3RXQ6 SIPA1L1 PTHR15711:SF10 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;regulation of cell projection organization#GO:0031344;regulation of synaptic plasticity#GO:0048167;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;organelle organization#GO:0006996;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;actin filament-based process#GO:0030029;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;regulation of dendritic spine morphogenesis#GO:0061001;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component organization#GO:0051128;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000009993.4|UniProtKB=G3R3D9 G3R3D9 SENP7 PTHR46896:SF2 SENTRIN-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 7 ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000016107.3|UniProtKB=G3S0J1 G3S0J1 IMPG2 PTHR12199:SF4 INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 2 ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;organic acid binding#GO:0043177;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000009042.3|UniProtKB=G3RYZ1 G3RYZ1 KDM4A PTHR10694:SF119 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4A dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;protein demethylase activity#GO:0140457;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000038267.1|UniProtKB=G3RMU4 G3RMU4 MRFAP1L1 PTHR31324:SF2 MORF4 FAMILY-ASSOCIATED PROTEIN 1-RELATED MORF4 FAMILY-ASSOCIATED PROTEIN 1-LIKE 1 GORGO|Ensembl=ENSGGOG00000004366.3|UniProtKB=G3QNZ9 G3QNZ9 MYF5 PTHR11534:SF3 MYOGENIC FACTOR MYOGENIC FACTOR 5 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;striated muscle tissue development#GO:0014706;positive regulation of cell differentiation#GO:0045597;muscle organ development#GO:0007517;animal organ development#GO:0048513;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;muscle tissue development#GO:0060537;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;skeletal muscle tissue development#GO:0007519;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000038411.1|UniProtKB=A0A2I2YPG6 A0A2I2YPG6 LENEP PTHR16968:SF2 LENS EPITHELIAL CELL PROTEIN LEP503 LENS EPITHELIAL CELL PROTEIN LEP503 GORGO|Ensembl=ENSGGOG00000038514.1|UniProtKB=A0A2I2Z844 A0A2I2Z844 KCNJ2 PTHR11767:SF43 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 2 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000013055.3|UniProtKB=G3RB95 G3RB95 MYLIP PTHR23280:SF13 4.1 G PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MYLIP ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000016773.3|UniProtKB=G3SE16 G3SE16 WIPF1 PTHR48226:SF1 OS06G0326200 PROTEIN WAS_WASL-INTERACTING PROTEIN FAMILY MEMBER 1 cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 actin filament-based process#GO:0030029;cellular process#GO:0009987;actin filament-based movement#GO:0030048 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884 GORGO|Ensembl=ENSGGOG00000003215.3|UniProtKB=A0A2I2ZY39 A0A2I2ZY39 RARG PTHR24085:SF7 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR GAMMA transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to peptide hormone stimulus#GO:0071375;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of DNA-templated transcription#GO:0006355;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000022357.2|UniProtKB=G3SBU7 G3SBU7 PTHR10496:SF7 40S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN ES24 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000040777.1|UniProtKB=A0A2I2ZJ95 A0A2I2ZJ95 PTHR10351:SF28 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013643.3|UniProtKB=A0A2I2YBI3 A0A2I2YBI3 ZNF641 PTHR23226:SF451 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 641 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002859.4|UniProtKB=G3QK53 G3QK53 DIAPH2 PTHR45691:SF3 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 2 actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 GORGO|Ensembl=ENSGGOG00000003858.3|UniProtKB=G3QMP4 G3QMP4 KRT3 PTHR45616:SF38 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 3 structural molecule activity#GO:0005198 cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;cytoskeleton organization#GO:0007010;skin development#GO:0043588;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;epidermis development#GO:0008544;developmental process#GO:0032502 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000037111.1|UniProtKB=G3RKC6 G3RKC6 B9D2 PTHR12968:SF2 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 cilium#GO:0005929;ciliary transition zone#GO:0035869;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000000253.3|UniProtKB=G3QDD6 G3QDD6 MAP1LC3C PTHR10969:SF50 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 GAMMA phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;lipid binding#GO:0008289 cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;response to stress#GO:0006950;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;autophagosome membrane#GO:0000421;bounding membrane of organelle#GO:0098588;autophagosome#GO:0005776;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000006479.3|UniProtKB=G3QUE0 G3QUE0 AP1B1 PTHR11134:SF31 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-1 COMPLEX SUBUNIT BETA-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;membrane protein complex#GO:0098796;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005801.3|UniProtKB=G3QSP1 G3QSP1 PLEKHO2 PTHR15871:SF2 PH DOMAIN-CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY O MEMBER 2 apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219;programmed cell death#GO:0012501 GORGO|Ensembl=ENSGGOG00000008667.3|UniProtKB=G3QZZ9 G3QZZ9 TMEM132C PTHR13388:SF4 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132C cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000011407.3|UniProtKB=G3R6Z7 G3R6Z7 CCDC85A PTHR13546:SF13 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85A GORGO|Ensembl=ENSGGOG00000000726.3|UniProtKB=G3QEL8 G3QEL8 PPP1R18 PTHR21685:SF0 TON-B BOX DOMAIN PHOSTENSIN GORGO|Ensembl=ENSGGOG00000009658.3|UniProtKB=G3SEH1 G3SEH1 ARHGAP25 PTHR15228:SF20 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 25 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;negative regulation of signal transduction#GO:0009968;membrane invagination#GO:0010324;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;endocytosis#GO:0006897;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of response to stimulus#GO:0048585;membrane organization#GO:0061024;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;phagocytosis#GO:0006909;transport#GO:0006810;regulation of response to stimulus#GO:0048583;establishment of localization#GO:0051234;actin filament organization#GO:0007015;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;actin filament-based process#GO:0030029;localization#GO:0051179;supramolecular fiber organization#GO:0097435 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000011902.3|UniProtKB=G3R8A9 G3R8A9 EXOSC8 PTHR11097:SF9 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP43 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of 5.8S rRNA#GO:0000460;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;snRNA 3'-end processing#GO:0034472;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;snRNA processing#GO:0016180;regulation of gene expression#GO:0010468;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA metabolic process#GO:0016073;rRNA processing#GO:0006364 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000037248.1|UniProtKB=A0A2I2ZK34 A0A2I2ZK34 RBM8A PTHR45894:SF1 RNA-BINDING PROTEIN 8A RNA-BINDING PROTEIN 8A RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000000045.3|UniProtKB=G3QCU7 G3QCU7 MAP3K6 PTHR11584:SF391 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 6 MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;JNK cascade#GO:0007254;p38MAPK cascade#GO:0038066;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>MEKK1-5#P00634 GORGO|Ensembl=ENSGGOG00000017156.3|UniProtKB=G3RWH9 G3RWH9 SMG6 PTHR15696:SF0 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 TELOMERASE-BINDING PROTEIN EST1A nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;RNA binding#GO:0003723;DNA binding#GO:0003677 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000039590.1|UniProtKB=A0A2I2YTR4 A0A2I2YTR4 PTHR23334:SF5 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN ALPHA RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000036446.1|UniProtKB=A0A2I2ZC58 A0A2I2ZC58 RNF4 PTHR23041:SF82 RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF4 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA repair#GO:0006281;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000008600.3|UniProtKB=A0A2I2Z7A4 A0A2I2Z7A4 FMNL2 PTHR45857:SF5 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cell migration#GO:0016477;cell motility#GO:0048870;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013940.3|UniProtKB=G3RDJ1 G3RDJ1 ZNF233 PTHR24377:SF705 IP01015P-RELATED ZINC FINGER PROTEIN 233 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014025.3|UniProtKB=G3RDS2 G3RDS2 ABRAXAS2 PTHR31728:SF1 ABRAXAS FAMILY MEMBER BRISC COMPLEX SUBUNIT ABRAXAS 2 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;attachment of spindle microtubules to kinetochore#GO:0008608;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;organelle assembly#GO:0070925;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000004350.3|UniProtKB=G3QNY8 G3QNY8 FBXW5 PTHR20995:SF17 F-BOX/WD REPEAT-CONTAINING PROTEIN 5 F-BOX_WD REPEAT-CONTAINING PROTEIN 5 GORGO|Ensembl=ENSGGOG00000026886.2|UniProtKB=A0A2I2ZHM4 A0A2I2ZHM4 ZYG11B PTHR12904:SF21 FAMILY NOT NAMED PROTEIN ZYG-11 HOMOLOG B ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462 GORGO|Ensembl=ENSGGOG00000040856.1|UniProtKB=A0A2I2ZSY5 A0A2I2ZSY5 LOC101151955 PTHR14224:SF90 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 SUBFAMILY NOT NAMED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul2-RING ubiquitin ligase complex#GO:0031462;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000011122.3|UniProtKB=G3R697 G3R697 RNF41 PTHR15315:SF122 RING FINGER PROTEIN 41, 151 E3 UBIQUITIN-PROTEIN LIGASE NRDP1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum tubular network#GO:0071782;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000001707.3|UniProtKB=A0A2I2YR16 A0A2I2YR16 LOC101131222 PTHR23430:SF20 HISTONE H2A CORE HISTONE MACRO-H2A.1 structural molecule activity#GO:0005198 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;regulation of transcription by RNA polymerase I#GO:0006356;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000012019.3|UniProtKB=G3RM65 G3RM65 CYFIP2 PTHR12195:SF5 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN 2 post-transcriptional regulation of gene expression#GO:0010608;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;axon guidance#GO:0007411;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;anatomical structure development#GO:0048856;system development#GO:0048731;programmed cell death#GO:0012501;cell death#GO:0008219;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;regulation of protein metabolic process#GO:0051246;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468 neuron projection#GO:0043005;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 GORGO|Ensembl=ENSGGOG00000026557.2|UniProtKB=A0A2I2YK61 A0A2I2YK61 HCFC2 PTHR46003:SF2 HOST CELL FACTOR HOST CELL FACTOR 2 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708 GORGO|Ensembl=ENSGGOG00000002747.3|UniProtKB=A0A2I2Y884 A0A2I2Y884 TAF6 PTHR10221:SF9 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP#P00670;General transcription regulation#P00023>TBP-associated factors#P00658 GORGO|Ensembl=ENSGGOG00000013571.4|UniProtKB=G3RCK7 G3RCK7 FBXO47 PTHR34098:SF1 F-BOX ONLY PROTEIN 47 F-BOX ONLY PROTEIN 47 GORGO|Ensembl=ENSGGOG00000006052.3|UniProtKB=G3SHC6 G3SHC6 MOK PTHR24055:SF533 MITOGEN-ACTIVATED PROTEIN KINASE MAPK_MAK_MRK OVERLAPPING KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000008276.3|UniProtKB=A0A2I2ZHD5 A0A2I2ZHD5 ZNF485 PTHR24377:SF867 IP01015P-RELATED ZINC FINGER PROTEIN 485 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002642.3|UniProtKB=G3QJK5 G3QJK5 PTHR46799:SF1 HOMEOBOX PROTEIN UNC-4 HOMOLOG HOMEOBOX PROTEIN UNC-4 HOMOLOG double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Gene=NDUFV2|UniProtKB=Q0MQI8 Q0MQI8 NDUFV2 PTHR10371:SF3 NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176;dehydrogenase#PC00092 Parkinson disease#P00049>Complex I#P01237 GORGO|Ensembl=ENSGGOG00000010852.3|UniProtKB=G3R5K4 G3R5K4 LOC101130358 PTHR24299:SF7 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1A2 catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;estrogen metabolic process#GO:0008210;steroid catabolic process#GO:0006706;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;xenobiotic metabolic process#GO:0006805;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;secondary metabolic process#GO:0019748;lipid catabolic process#GO:0016042;cellular process#GO:0009987;hormone metabolic process#GO:0042445;response to chemical#GO:0042221;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;cellular response to xenobiotic stimulus#GO:0071466 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000004004.3|UniProtKB=G3SIQ2 G3SIQ2 DGUOK PTHR10513:SF8 DEOXYNUCLEOSIDE KINASE DEOXYGUANOSINE KINASE, MITOCHONDRIAL deoxynucleoside kinase activity#GO:0019136;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003448.3|UniProtKB=G3QLN1 G3QLN1 GBGT1 PTHR10462:SF49 GLYCOSYLTRANSFERASE-RELATED GLOBOSIDE ALPHA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vesicle#GO:0031982 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000022753.2|UniProtKB=G3SHC4 G3SHC4 PAIP1 PTHR23254:SF15 EIF4G DOMAIN PROTEIN POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1 translation regulator activity#GO:0045182 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001042.3|UniProtKB=G3QFF6 G3QFF6 GAB3 PTHR45960:SF3 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 3 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Gab#P00563 GORGO|Ensembl=ENSGGOG00000028266.2|UniProtKB=A0A2I2YL22 A0A2I2YL22 LOC101152265 PTHR10394:SF14 40S RIBOSOMAL PROTEIN S8 40S RIBOSOMAL PROTEIN S8 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000002300.3|UniProtKB=G3QIP7 G3QIP7 TANK PTHR15249:SF0 TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR Toll receptor signaling pathway#P00054>TANK#P01353 GORGO|Ensembl=ENSGGOG00000001632.3|UniProtKB=A0A2I2YP88 A0A2I2YP88 KIF21A PTHR24115:SF398 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF21A tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000005612.3|UniProtKB=G3QS67 G3QS67 CD244 PTHR12080:SF56 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE NATURAL KILLER CELL RECEPTOR 2B4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;immune system process#GO:0002376;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000022930.2|UniProtKB=G3RZC5 G3RZC5 SKP1 PTHR11165:SF189 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015200.3|UniProtKB=G3RLZ9 G3RLZ9 LMOD3 PTHR10901:SF3 TROPOMODULIN LEIOMODIN-3 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;muscle contraction#GO:0006936;developmental process#GO:0032502;system process#GO:0003008;actin filament organization#GO:0007015;cellular developmental process#GO:0048869 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;M band#GO:0031430;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;A band#GO:0031672;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000016287.3|UniProtKB=G3RJK4 G3RJK4 GPT2 PTHR11751:SF311 ALANINE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE 2 transferase#PC00220;transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000025427.2|UniProtKB=G3RUF5 G3RUF5 RPL13 PTHR11722:SF4 60S RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN EL13 binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001337.3|UniProtKB=A0A2I2YR26 A0A2I2YR26 PRDX5 PTHR10430:SF41 PEROXIREDOXIN PEROXIREDOXIN-5, MITOCHONDRIAL antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 cellular response to stimulus#GO:0051716;homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;mitochondrion#GO:0005739;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000039581.1|UniProtKB=G3R3H7 G3R3H7 CEACAM21 PTHR12080:SF82 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CELL ADHESION MOLECULE CEACAM21 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;macromolecule localization#GO:0033036;regulation of biological process#GO:0050789;signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;localization#GO:0051179;cell communication#GO:0007154;intracellular protein localization#GO:0008104;immune system process#GO:0002376;protein localization to cell junction#GO:1902414 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000016301.3|UniProtKB=A0A2I2YSB4 A0A2I2YSB4 LOC101152583 PTHR45616:SF64 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CUTICULAR HB1 structural molecule activity#GO:0005198 keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;epidermis development#GO:0008544;developmental process#GO:0032502;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;skin development#GO:0043588 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000005829.3|UniProtKB=G3QSR2 G3QSR2 ITLN2 PTHR16146:SF21 INTELECTIN INTELECTIN-2 carbohydrate binding#GO:0030246;binding#GO:0005488;oligosaccharide binding#GO:0070492 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000011999.3|UniProtKB=A0A2I2ZJL2 A0A2I2ZJL2 LOC101130393 PTHR11431:SF47 FERRITIN FERRITIN LIGHT CHAIN cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000002976.3|UniProtKB=G3QKF2 G3QKF2 FBXO32 PTHR13123:SF6 LD30288P F-BOX ONLY PROTEIN 32 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000025616.2|UniProtKB=G3RMM0 G3RMM0 PLAT PTHR24264:SF42 TRYPSIN-RELATED TISSUE-TYPE PLASMINOGEN ACTIVATOR catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 plasminogen activation#GO:0031639;signal transduction#GO:0007165;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;cell migration#GO:0016477;protein maturation#GO:0051604;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;zymogen activation#GO:0031638;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;proteolysis#GO:0006508;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;protein metabolic process#GO:0019538;enzyme-linked receptor protein signaling pathway#GO:0007167 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 Blood coagulation#P00011>tPA#P00431;Plasminogen activating cascade#P00050>pro-tPA#P01249;Plasminogen activating cascade#P00050>tPA#P01257 GORGO|Ensembl=ENSGGOG00000000781.3|UniProtKB=G3QES0 G3QES0 CFD PTHR24271:SF54 KALLIKREIN-RELATED COMPLEMENT FACTOR D catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000016103.3|UniProtKB=G3RJ37 G3RJ37 UQCC6 PTHR28492:SF1 HYPOTHETICAL PROTEIN LOC691921 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 6 mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000037511.1|UniProtKB=A0A2I2ZXV7 A0A2I2ZXV7 PTHR24012:SF692 RNA BINDING PROTEIN CYTOTOXIC GRANULE ASSOCIATED RNA BINDING PROTEIN TIA1 mRNA binding#GO:0003729;binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012285.3|UniProtKB=G3R9A9 G3R9A9 PTHR14269:SF17 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING 5 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000001254.3|UniProtKB=G3QFZ2 G3QFZ2 GRINA PTHR23291:SF16 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 1 calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803 regulation of apoptotic process#GO:0042981;negative regulation of signal transduction#GO:0009968;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;negative regulation of neuron apoptotic process#GO:0043524;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular process#GO:0009987;response to unfolded protein#GO:0006986;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;endoplasmic reticulum unfolded protein response#GO:0030968;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;cellular response to topologically incorrect protein#GO:0035967;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 ion channel#PC00133;transporter#PC00227 Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 GORGO|Ensembl=ENSGGOG00000010538.3|UniProtKB=A0A2I2YRE4 A0A2I2YRE4 ARHGEF4 PTHR47544:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000008578.3|UniProtKB=G3QZS4 G3QZS4 CD86 PTHR25466:SF2 T-LYMPHOCYTE ACTIVATION ANTIGEN T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>B7#P01337 GORGO|Ensembl=ENSGGOG00000014151.3|UniProtKB=G3RE35 G3RE35 PTHR46147:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 SET-BINDING PROTEIN methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000010338.3|UniProtKB=G3R493 G3R493 PARD6B PTHR14102:SF4 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG BETA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization or biogenesis#GO:0071840;cell-cell junction maintenance#GO:0045217;microtubule cytoskeleton organization#GO:0000226;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;establishment or maintenance of cell polarity#GO:0007163;cell-cell junction organization#GO:0045216;cell junction organization#GO:0034330;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cellular process#GO:0009987 protein kinase complex#GO:1902911;transferase complex#GO:1990234;apical part of cell#GO:0045177;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;apical plasma membrane#GO:0016324 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000042434.1|UniProtKB=A0A2I2Z5B2 A0A2I2Z5B2 TMEM95 PTHR38808:SF1 TRANSMEMBRANE PROTEIN 95 SPERM-EGG FUSION PROTEIN TMEM95 reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;single fertilization#GO:0007338;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;cellular process#GO:0009987;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;acrosomal membrane#GO:0002080;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503 GORGO|Ensembl=ENSGGOG00000039481.1|UniProtKB=A0A2I2YMF4 A0A2I2YMF4 PTHR10110:SF167 SODIUM/HYDROGEN EXCHANGER CATION_H+ EXCHANGER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000012938.3|UniProtKB=A0A2I2Z637 A0A2I2Z637 SCN5A PTHR10037:SF206 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;nervous system process#GO:0050877;sensory perception#GO:0007600;regulation of cellular process#GO:0050794;regulation of heart contraction#GO:0008016;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;sensory perception of pain#GO:0019233;sodium ion transport#GO:0006814;action potential#GO:0001508;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;system process#GO:0003008;regulation of system process#GO:0044057;transport#GO:0006810;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000001302.3|UniProtKB=G3QG35 G3QG35 FCRL5 PTHR11481:SF68 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 5 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000025358.2|UniProtKB=G3S1W4 G3S1W4 OR8I2 PTHR48018:SF73 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8I2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000516.3|UniProtKB=G3QE22 G3QE22 ATP5MJ PTHR15233:SF2 MITOCHONDRIAL PROTEOLIPID ATP SYNTHASE MEMBRANE SUBUNIT J transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000015996.3|UniProtKB=G3RIU2 G3RIU2 ACTN3 PTHR11915:SF432 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-3 binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;muscle cell differentiation#GO:0042692;cellular component organization#GO:0016043;muscle cell development#GO:0055001;cell development#GO:0048468;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856 I band#GO:0031674;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054;Z disc#GO:0030018;cell periphery#GO:0071944;contractile muscle fiber#GO:0043292;membrane#GO:0016020;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 GORGO|Ensembl=ENSGGOG00000025241.2|UniProtKB=G3SJ73 G3SJ73 SOX30 PTHR47279:SF1 TRANSCRIPTION FACTOR SOX-30 TRANSCRIPTION FACTOR SOX-30 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000011211.3|UniProtKB=G3R6H7 G3R6H7 SLC1A4 PTHR11958:SF20 SODIUM/DICARBOXYLATE SYMPORTER-RELATED NEUTRAL AMINO ACID TRANSPORTER A transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;sodium:dicarboxylate symporter activity#GO:0017153;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370 L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;L-glutamate import#GO:0051938;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000012553.3|UniProtKB=G3RSA3 G3RSA3 GATAD2B PTHR13455:SF4 TRANSCRIPTIONAL REPRESSOR P66-RELATED TRANSCRIPTIONAL REPRESSOR P66-BETA transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000002876.3|UniProtKB=G3QK59 G3QK59 FHL3 PTHR24205:SF5 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 3 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000003954.3|UniProtKB=A0A2I2YRV3 A0A2I2YRV3 CEP55 PTHR31838:SF1 CENTROSOMAL PROTEIN OF 55 KDA CENTROSOMAL PROTEIN OF 55 KDA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;cellular process#GO:0009987;establishment of protein localization#GO:0045184;mitotic cytokinetic process#GO:1902410;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell division#GO:0051301;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell cycle#GO:0007049 cellular anatomical structure#GO:0110165;midbody#GO:0030496 GORGO|Ensembl=ENSGGOG00000040750.1|UniProtKB=A0A2I2ZJ41 A0A2I2ZJ41 UBE2E2 PTHR24068:SF429 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;ISG15-protein conjugation#GO:0032020;post-translational protein modification#GO:0043687;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein K11-linked ubiquitination#GO:0070979;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000009524.3|UniProtKB=G3R274 G3R274 DOCK6 PTHR23317:SF65 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 6 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000001792.3|UniProtKB=A0A2I2ZI75 A0A2I2ZI75 GRHL3 PTHR11037:SF6 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 3 HOMOLOG DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000001713.3|UniProtKB=G3QH64 G3QH64 PRRG2 PTHR24278:SF30 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 2 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000026007.2|UniProtKB=A0A2I2YNY7 A0A2I2YNY7 LOC101143155 PTHR23001:SF24 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2 translation initiation factor binding#GO:0031369;translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051;RNA binding#GO:0003723;protein binding#GO:0005515;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000034835.2|UniProtKB=G3SKK8 G3SKK8 SLC26A10P PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;carboxylic acid transmembrane transporter activity#GO:0046943 transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012178.3|UniProtKB=G3R915 G3R915 MCOLN2 PTHR12127:SF4 MUCOLIPIN MUCOLIPIN-2 calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013830.3|UniProtKB=G3RD97 G3RD97 SORBS2 PTHR14167:SF56 SH3 DOMAIN-CONTAINING SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cytoskeleton organization#GO:0007010;cell surface receptor signaling pathway#GO:0007166;Notch signaling pathway#GO:0007219;cell communication#GO:0007154;cellular component organization or biogenesis#GO:0071840 cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic tree#GO:0097447;dendrite#GO:0030425;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027939.2|UniProtKB=G3RM54 G3RM54 IER3IP1 PTHR15858:SF7 IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1 IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1 regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;positive regulation of secretion#GO:0051047;regulation of secretion by cell#GO:1903530;regulation of protein localization#GO:0032880;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;regulation of establishment of protein localization#GO:0070201;cellular localization#GO:0051641;localization#GO:0051179;regulation of secretion#GO:0051046;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;establishment of localization in cell#GO:0051649;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of protein secretion#GO:0050714;establishment of localization#GO:0051234 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000039195.1|UniProtKB=G3REX0 G3REX0 LOC101149433 PTHR23427:SF15 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 1 protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000011773.3|UniProtKB=G3R7Z1 G3R7Z1 EIF2AK3 PTHR11042:SF166 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 3 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2AK3#P06813 GORGO|Ensembl=ENSGGOG00000013573.3|UniProtKB=G3S1M9 G3S1M9 CSF3R PTHR23036:SF103 CYTOKINE RECEPTOR GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000043032.1|UniProtKB=A0A2I2YUV0 A0A2I2YUV0 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of protein stability#GO:0031647;regulation of programmed cell death#GO:0043067;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000038575.1|UniProtKB=G3RVN7 G3RVN7 PTHR12015:SF103 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 4-LIKE cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to peptide#GO:1901652;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;taxis#GO:0042330;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;regulation of cell motility#GO:2000145;cell chemotaxis#GO:0060326;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;biological regulation#GO:0065007;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;positive regulation of locomotion#GO:0040017;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000010856.3|UniProtKB=G3R5L0 G3R5L0 GPSM1 PTHR45954:SF2 LD33695P G PROTEIN-SIGNALING MODULATOR 1 binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;localization#GO:0051179;spindle localization#GO:0051653;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;establishment of cell polarity#GO:0030010;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;mitotic cell cycle process#GO:1903047;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;cytoskeleton organization#GO:0007010 cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>AGS3#P00715;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>AGS3#P00739 GORGO|Ensembl=ENSGGOG00000000721.3|UniProtKB=G3QEL2 G3QEL2 PTHR24237:SF7 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183 signaling receptor activity#GO:0038023;steroid binding#GO:0005496;G protein-coupled receptor activity#GO:0004930;lipid binding#GO:0008289;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;sterol binding#GO:0032934 response to chemical#GO:0042221;lymphocyte activation#GO:0046649;taxis#GO:0042330;regulation of multicellular organismal process#GO:0051239;regulation of mononuclear cell proliferation#GO:0032944;regulation of B cell activation#GO:0050864;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;lymphocyte activation involved in immune response#GO:0002285;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of leukocyte proliferation#GO:0070663;B cell activation#GO:0042113;regulation of B cell proliferation#GO:0030888;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;positive regulation of leukocyte activation#GO:0002696;response to stimulus#GO:0050896;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;cell activation involved in immune response#GO:0002263;B cell activation involved in immune response#GO:0002312;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell migration#GO:0016477;multicellular organismal process#GO:0032501;regulation of lymphocyte proliferation#GO:0050670;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;leukocyte migration#GO:0050900;positive regulation of leukocyte proliferation#GO:0070665;cell motility#GO:0048870;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;locomotion#GO:0040011;positive regulation of B cell proliferation#GO:0030890;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;cell chemotaxis#GO:0060326;cell activation#GO:0001775;positive regulation of lymphocyte proliferation#GO:0050671;chemotaxis#GO:0006935 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000013352.3|UniProtKB=G3RC09 G3RC09 COLGALT2 PTHR10730:SF8 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN GALACTOSYLTRANSFERASE 2 galactosyltransferase activity#GO:0008378;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012891.3|UniProtKB=G3RAU8 G3RAU8 ACRV1 PTHR17571:SF34 URINARY PROTEIN RUP /ACROSOMAL PROTEIN SP-10 ACROSOMAL PROTEIN SP-10 vesicle#GO:0031982;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000011223.3|UniProtKB=G3R6J1 G3R6J1 CLCN1 PTHR45720:SF4 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 1 voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010252.4|UniProtKB=G3R422 G3R422 DCBLD2 PTHR46806:SF3 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;wound healing#GO:0042060;response to stress#GO:0006950;response to wounding#GO:0009611 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000012409.3|UniProtKB=A0A2I2YH27 A0A2I2YH27 DYRK3 PTHR24058:SF35 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cellular component organization#GO:0016043;regulation of cell cycle phase transition#GO:1901987;protein-containing complex disassembly#GO:0032984;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of cell cycle G2/M phase transition#GO:1902749;organelle organization#GO:0006996;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006476.3|UniProtKB=G3QUE2 G3QUE2 PTHR22730:SF6 PROMININ PROM PROTEIN PROMININ-2 cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cellular process#GO:0009987 actin-based cell projection#GO:0098858;microvillus#GO:0005902;vesicle#GO:0031982;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000025418.2|UniProtKB=G3S396 G3S396 TLR10 PTHR24365:SF23 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 10 signaling receptor binding#GO:0005102;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515;lipid binding#GO:0008289;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 GORGO|Ensembl=ENSGGOG00000008860.3|UniProtKB=G3R0H9 G3R0H9 OLFML2B PTHR23192:SF37 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 2B regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000011952.3|UniProtKB=G3RZY4 G3RZY4 ABCA12 PTHR19229:SF29 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA GLUCOSYLCERAMIDE TRANSPORTER ABCA12 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;protein binding#GO:0005515;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000012102.3|UniProtKB=A0A2I2Y378 A0A2I2Y378 SEL1L PTHR11102:SF70 SEL-1-LIKE PROTEIN PROTEIN SEL-1 HOMOLOG 1 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000004448.3|UniProtKB=A0A2I2YPA0 A0A2I2YPA0 WBP11 PTHR13361:SF1 WW DOMAIN-BINDING PROTEIN 11 WW DOMAIN-BINDING PROTEIN 11 molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 GORGO|Ensembl=ENSGGOG00000012739.3|UniProtKB=G3RAF5 G3RAF5 LOC101142742 PTHR19969:SF18 SH2-SH3 ADAPTOR PROTEIN-RELATED GRB2 RELATED ADAPTOR PROTEIN B protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090 cell motility#GO:0048870;cell migration#GO:0016477;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000012524.3|UniProtKB=A0A2I2ZM13 A0A2I2ZM13 PTHR23068:SF10 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3A catalytic activity, acting on DNA#GO:0140097;transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity, acting on a nucleic acid#GO:0140640 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA methyltransferase#PC00013 GORGO|Ensembl=ENSGGOG00000011001.3|UniProtKB=G3R5Y8 G3R5Y8 ZBP1 PTHR14966:SF0 Z-DNA-BINDING PROTEIN 1 Z-DNA-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;defense response to virus#GO:0051607;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;immune system process#GO:0002376;positive regulation of cytokine-mediated signaling pathway#GO:0001961;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;regulation of response to cytokine stimulus#GO:0060759;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;regulation of apoptotic process#GO:0042981;regulation of cytokine-mediated signaling pathway#GO:0001959;positive regulation of response to external stimulus#GO:0032103;positive regulation of apoptotic process#GO:0043065;antiviral innate immune response#GO:0140374;positive regulation of signal transduction#GO:0009967;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to virus#GO:0009615;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;defense response#GO:0006952;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000001359.3|UniProtKB=G3QG91 G3QG91 CCDC174 PTHR15885:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009613.3|UniProtKB=G3SGG6 G3SGG6 NLGN4X PTHR43903:SF25 NEUROLIGIN NEUROLIGIN-4, X-LINKED cell junction#GO:0030054;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;synaptic membrane#GO:0097060;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;organelle#GO:0043226;plasma membrane#GO:0005886;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000027345.2|UniProtKB=G3SAL7 G3SAL7 PTHR46370:SF1 GPALPP MOTIFS-CONTAINING PROTEIN 1 GPALPP MOTIFS-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000001675.3|UniProtKB=G3QH32 G3QH32 MS4A7 PTHR23320:SF8 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 7 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010208.3|UniProtKB=G3R3X3 G3R3X3 TXNDC12 PTHR15337:SF10 ANTERIOR GRADIENT PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 12 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010324.3|UniProtKB=A0A2I2Y1Q4 A0A2I2Y1Q4 PEX26 PTHR11588:SF140 TUBULIN TUBULIN ALPHA-8 CHAIN small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 tubulin#PC00228;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000024661.2|UniProtKB=G3RND1 G3RND1 SELL PTHR19325:SF543 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING L-SELECTIN organic acid binding#GO:0043177;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;carbohydrate derivative binding#GO:0097367;oligosaccharide binding#GO:0070492;carbohydrate binding#GO:0030246 response to peptide#GO:1901652;cell adhesion#GO:0007155;immune system process#GO:0002376;leukocyte migration#GO:0050900;cell migration#GO:0016477;cell motility#GO:0048870;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;leukocyte cell-cell adhesion#GO:0007159;cell-cell adhesion#GO:0098609 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 complement component#PC00078;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000001242.3|UniProtKB=G3QFY5 G3QFY5 IZUMO1 PTHR35540:SF1 IZUMO SPERM-EGG FUSION PROTEIN 1 IZUMO SPERM-EGG FUSION PROTEIN 1 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cell-cell adhesion mediator activity#GO:0098632;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488 single fertilization#GO:0007338;cellular process#GO:0009987;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;fertilization#GO:0009566;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;sperm-egg recognition#GO:0035036;cell recognition#GO:0008037;sexual reproduction#GO:0019953;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609;cell-cell recognition#GO:0009988 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;acrosomal membrane#GO:0002080;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708 GORGO|Ensembl=ENSGGOG00000014354.3|UniProtKB=G3REM1 G3REM1 AGBL2 PTHR12756:SF41 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 2 metallopeptidase activity#GO:0008237;binding#GO:0005488;carboxypeptidase activity#GO:0004180;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;protein binding#GO:0005515;exopeptidase activity#GO:0008238;metalloexopeptidase activity#GO:0008235;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000002832.3|UniProtKB=A0A2I2YEC3 A0A2I2YEC3 C20H19orf25 PTHR34766:SF1 UPF0449 PROTEIN C19ORF25 UPF0449 PROTEIN C19ORF25 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 GORGO|Ensembl=ENSGGOG00000001534.3|UniProtKB=A0A2I2ZBS4 A0A2I2ZBS4 MINDY1 PTHR18063:SF7 NF-E2 INDUCIBLE PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-1 carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000016987.3|UniProtKB=G3RLD5 G3RLD5 ADISSP PTHR13287:SF6 ADIPOSE-SECRETED SIGNALING PROTEIN ADIPOSE-SECRETED SIGNALING PROTEIN adaptive thermogenesis#GO:1990845;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;homeostatic process#GO:0042592;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;temperature homeostasis#GO:0001659;multicellular organismal-level homeostasis#GO:0048871;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000027365.2|UniProtKB=G3SE29 G3SE29 PTHR19269:SF73 TROPOMYOSIN TROPOMYOSIN 3, RELATED SEQUENCE 7 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 cellular process#GO:0009987;muscle system process#GO:0003012;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;multicellular organismal process#GO:0032501;actin filament-based process#GO:0030029;muscle contraction#GO:0006936;system process#GO:0003008;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 actin binding motor protein#PC00040 GORGO|Ensembl=ENSGGOG00000009967.3|UniProtKB=G3R3A8 G3R3A8 PAK4 PTHR45832:SF9 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517 GORGO|Ensembl=ENSGGOG00000039366.1|UniProtKB=A0A2I2Y9C3 A0A2I2Y9C3 ACKR4 PTHR10489:SF733 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 4 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;locomotion#GO:0040011;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000009731.3|UniProtKB=G3R2P9 G3R2P9 RGS11 PTHR45746:SF3 LP21163P REGULATOR OF G PROTEIN SIGNALING 11 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 GORGO|Ensembl=ENSGGOG00000013811.3|UniProtKB=A0A2I2YC52 A0A2I2YC52 GASK1B PTHR15905:SF1 GOLGI-ASSOCIATED KINASE 1B-RELATED GOLGI-ASSOCIATED KINASE 1B GORGO|Ensembl=ENSGGOG00000004740.3|UniProtKB=G3QPY4 G3QPY4 NT5C PTHR16504:SF5 5'(3')-DEOXYRIBONUCLEOTIDASE 5'(3')-DEOXYRIBONUCLEOTIDASE, CYTOSOLIC TYPE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;nucleobase-containing compound metabolic process#GO:0006139;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136 GORGO|Ensembl=ENSGGOG00000023789.2|UniProtKB=G3SC62 G3SC62 PCM1 PTHR14164:SF12 PERICENTRIOLAR MATERIAL 1-RELATED PERICENTRIOLAR MATERIAL 1 PROTEIN cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000042671.1|UniProtKB=A0A2I2Y6V0 A0A2I2Y6V0 MDFIC PTHR15304:SF0 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of JNK cascade#GO:0046328 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006670.3|UniProtKB=G3SCX6 G3SCX6 TRARG1 PTHR14948:SF1 NG5 TRAFFICKING REGULATOR OF GLUT4 1 cellular response to peptide hormone stimulus#GO:0071375;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;localization#GO:0051179;response to nitrogen compound#GO:1901698;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;cellular response to nitrogen compound#GO:1901699;response to peptide hormone#GO:0043434;macromolecule localization#GO:0033036;endosome to plasma membrane protein transport#GO:0099638;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;cellular response to insulin stimulus#GO:0032869;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;endocytic recycling#GO:0032456;cellular response to hormone stimulus#GO:0032870;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;cellular localization#GO:0051641;protein transport#GO:0015031;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;vesicle-mediated transport#GO:0016192;establishment of protein localization to membrane#GO:0090150;response to hormone#GO:0009725;establishment of localization in cell#GO:0051649;cellular response to oxygen-containing compound#GO:1901701;establishment of protein localization#GO:0045184;cellular process#GO:0009987;endosomal transport#GO:0016197;protein localization to cell periphery#GO:1990778;intracellular protein transport#GO:0006886 cytoplasmic vesicle membrane#GO:0030659;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular vesicle#GO:0097708;vesicle membrane#GO:0012506;vesicle#GO:0031982;organelle membrane#GO:0031090;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000028038.2|UniProtKB=G3S4R9 G3S4R9 LOC101125919 PTHR31156:SF11 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E4 GORGO|Ensembl=ENSGGOG00000011688.3|UniProtKB=G3R7Q7 G3R7Q7 PTHR10174:SF200 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED RETINALDEHYDE-BINDING PROTEIN 1 phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000028449.2|UniProtKB=G3S046 G3S046 LMOD1 PTHR10901:SF5 TROPOMODULIN LEIOMODIN-1 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;muscle contraction#GO:0006936;developmental process#GO:0032502;cellular developmental process#GO:0048869;system process#GO:0003008;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061 contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000012222.3|UniProtKB=G3R952 G3R952 TRIP10 PTHR15735:SF17 FCH AND DOUBLE SH3 DOMAINS PROTEIN CDC42-INTERACTING PROTEIN 4 cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;regulation of actin filament-based process#GO:0032970;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000004924.3|UniProtKB=G3QQF8 G3QQF8 INMT PTHR10867:SF33 NNMT/PNMT/TEMT FAMILY MEMBER INDOLETHYLAMINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061;Nicotine degradation#P05914>INMT#P05981 GORGO|Ensembl=ENSGGOG00000040628.1|UniProtKB=A0A2I2Z0A5 A0A2I2Z0A5 LOC101153953 PTHR10562:SF141 SMALL UBIQUITIN-RELATED MODIFIER RAD60_SUMO-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899 primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein sumoylation#GO:0016925 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000014652.3|UniProtKB=G3RFD1 G3RFD1 PARVA PTHR12114:SF6 PARVIN ALPHA-PARVIN binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of biological quality#GO:0065008;cilium organization#GO:0044782;cell-substrate adhesion#GO:0031589;actin filament-based process#GO:0030029;cell adhesion#GO:0007155;establishment or maintenance of cell polarity#GO:0007163;organelle assembly#GO:0070925;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;cell projection organization#GO:0030030;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;substrate adhesion-dependent cell spreading#GO:0034446;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Parvin#P00945 GORGO|Ensembl=ENSGGOG00000027397.2|UniProtKB=G3S925 G3S925 SPATA2 PTHR15326:SF8 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;signaling adaptor activity#GO:0035591 regulation of inflammatory response#GO:0050727;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;regulation of response to stress#GO:0080134;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;regulation of response to cytokine stimulus#GO:0060759;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to external stimulus#GO:0032101 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000028095.2|UniProtKB=G3SF43 G3SF43 DCLRE1A PTHR23240:SF6 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED DNA CROSS-LINK REPAIR 1A PROTEIN hydrolase activity#GO:0016787;DNA binding#GO:0003677;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;5'-3' exonuclease activity#GO:0008409;exonuclease activity#GO:0004527;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;damaged DNA binding#GO:0003684;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000024505.2|UniProtKB=A0A2I2ZZ20 A0A2I2ZZ20 BOLA3 PTHR46188:SF1 BOLA-LIKE PROTEIN 3 BOLA-LIKE PROTEIN 3 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000002301.3|UniProtKB=A0A2I2Z265 A0A2I2Z265 RELN PTHR11841:SF1 REELIN REELIN protein binding#GO:0005515;lipoprotein particle receptor binding#GO:0070325;signaling receptor binding#GO:0005102;binding#GO:0005488 neurogenesis#GO:0022008;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;developmental process#GO:0032502;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell migration#GO:0016477;cellular process#GO:0009987;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell motility#GO:0048870;central nervous system development#GO:0007417;cell differentiation#GO:0030154 extracellular region#GO:0005576;neuron projection#GO:0043005;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000012376.3|UniProtKB=A0A2I2Z2T3 A0A2I2Z2T3 MAP2K7 PTHR47238:SF2 MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE HEMIPTEROUS non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>MKK4,7#P00637;EGF receptor signaling pathway#P00018>MKK4,7#P00555 GORGO|Ensembl=ENSGGOG00000009944.3|UniProtKB=G3R383 G3R383 ERMN PTHR47137:SF1 ERMIN ERMIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;morphogenesis of a branching structure#GO:0001763;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;actin filament organization#GO:0007015;regulation of cell projection organization#GO:0031344;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;regulation of biological quality#GO:0065008;actin filament-based process#GO:0030029 intracellular organelle#GO:0043229;axon#GO:0030424;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;actin-based cell projection#GO:0098858;cell body#GO:0044297;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell periphery#GO:0071944;neuron projection#GO:0043005;main axon#GO:0044304;cytoplasm#GO:0005737;myelin sheath#GO:0043209;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477 GORGO|Ensembl=ENSGGOG00000004205.3|UniProtKB=G3QNK6 G3QNK6 SEC61B PTHR13509:SF26 SEC61 SUBUNIT BETA PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;localization within membrane#GO:0051668;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620 membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum#GO:0005791 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011493.3|UniProtKB=G3R777 G3R777 SFN PTHR18860:SF14 14-3-3 PROTEIN 14-3-3 PROTEIN SIGMA protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;p53 pathway#P00059>14-3-3#P04628;p53 pathway#P00059>14-3-3#G01576;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624 GORGO|Ensembl=ENSGGOG00000008969.3|UniProtKB=A0A2I2ZDY3 A0A2I2ZDY3 GNPDA1 PTHR11280:SF8 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE DEAMINASE 1 identical protein binding#GO:0042802;deaminase activity#GO:0019239;hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;binding#GO:0005488;catalytic activity#GO:0003824 amino sugar catabolic process#GO:0046348;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 isomerase#PC00135 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 GORGO|Ensembl=ENSGGOG00000039383.1|UniProtKB=A0A2I2YR86 A0A2I2YR86 PTHR14978:SF3 BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN BETA-CATENIN-LIKE PROTEIN 1 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000004757.4|UniProtKB=G3QQ07 G3QQ07 PTHR24355:SF17 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 3 binding#GO:0005488;signaling receptor binding#GO:0005102;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 negative regulation of signaling#GO:0023057;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK3#P05941;Parkinson disease#P00049>GRK#P01234 GORGO|Ensembl=ENSGGOG00000027306.2|UniProtKB=A0A2I2YII9 A0A2I2YII9 PTHR46756:SF30 TRANSGELIN CALPONIN-2 cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;protein localization to microtubule cytoskeleton#GO:0072698;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of microtubule-based process#GO:0032886;microtubule bundle formation#GO:0001578;actin filament-based process#GO:0030029;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 cytoskeleton#GO:0005856;stress fiber#GO:0001725;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;microtubule cytoskeleton#GO:0015630;actomyosin#GO:0042641;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;microtubule end#GO:1990752;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000004672.3|UniProtKB=G3S776 G3S776 RCAN2 PTHR10300:SF5 CALCIPRESSIN CALCIPRESSIN-2 protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000027682.2|UniProtKB=A0A2I2Y7C1 A0A2I2Y7C1 EIF3L PTHR13242:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000011190.3|UniProtKB=G3R6F7 G3R6F7 TNFSF11 PTHR11471:SF3 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of cell differentiation#GO:0045597;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of signaling#GO:0023051;regulation of myeloid cell differentiation#GO:0045637;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of myeloid cell differentiation#GO:0045639;regulation of cell development#GO:0060284;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of developmental process#GO:0051094;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of developmental process#GO:0050793;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of apoptotic signaling pathway#GO:2001233;regulation of hemopoiesis#GO:1903706;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000016824.3|UniProtKB=A0A2I2YFU2 A0A2I2YFU2 SLC17A8 PTHR11662:SF207 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;carboxylic acid transmembrane transporter activity#GO:0046943 trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;localization#GO:0051179;cell communication#GO:0007154;cellular localization#GO:0051641;regulation of synapse structure or activity#GO:0050803;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192 cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;presynapse#GO:0098793;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 GORGO|Ensembl=ENSGGOG00000042785.1|UniProtKB=A0A2I2Z8I5 A0A2I2Z8I5 PTHR11905:SF140 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN A DISINTEGRIN AND METALLOPEPTIDASE DOMAIN 6-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;sex differentiation#GO:0007548;male gonad development#GO:0008584;multicellular organismal process#GO:0032501;gonad development#GO:0008406;metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;male sex differentiation#GO:0046661;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;animal organ development#GO:0048513;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;reproductive structure development#GO:0048608;reproductive process#GO:0022414;animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;reproductive system development#GO:0061458;system development#GO:0048731 membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000010053.3|UniProtKB=G3R3I3 G3R3I3 ASF1A PTHR12040:SF8 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1A histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000006724.3|UniProtKB=G3QV19 G3QV19 SLC9A6 PTHR10110:SF94 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 6 antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000015440.3|UniProtKB=G3RHF1 G3RHF1 KIT PTHR24416:SF46 TYROSINE-PROTEIN KINASE RECEPTOR MAST_STEM CELL GROWTH FACTOR RECEPTOR KIT protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;hemopoiesis#GO:0030097;biological regulation#GO:0065007;cell migration#GO:0016477;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of locomotion#GO:0040017;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cellular process#GO:0050794;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;positive regulation of signal transduction#GO:0009967;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell activation#GO:0001775;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;lymphocyte differentiation#GO:0030098;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cytokine-mediated signaling pathway#GO:0019221;response to cytokine#GO:0034097;lymphocyte activation#GO:0046649;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;B cell activation#GO:0042113;cell surface receptor signaling pathway#GO:0007166;cell development#GO:0048468;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;mononuclear cell differentiation#GO:1903131;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;leukocyte differentiation#GO:0002521;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;immune system process#GO:0002376 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013967.3|UniProtKB=G3S4J1 G3S4J1 TRIM62 PTHR24103:SF573 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM62 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008215.3|UniProtKB=G3QYT6 G3QYT6 CDC42SE1 PTHR13502:SF3 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR PROTEIN 1 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000016405.3|UniProtKB=G3RJV2 G3RJV2 GNAZ PTHR10218:SF65 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(Z) SUBUNIT ALPHA ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622 heterotrimeric G-protein#PC00117;G-protein#PC00020 Dopamine receptor mediated signaling pathway#P05912>GNAZ#P05964 GORGO|Ensembl=ENSGGOG00000039527.1|UniProtKB=A0A2I2YSN0 A0A2I2YSN0 PTHR11620:SF106 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011152.3|UniProtKB=G3R6C9 G3R6C9 CSK PTHR24418:SF472 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE CSK catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell junction organization#GO:0034330;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 CCKR signaling map#P06959>CSK#P07072;T cell activation#P00053>Csk#P01304;Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Csk#P00913 GORGO|Ensembl=ENSGGOG00000011181.3|UniProtKB=G3R6F0 G3R6F0 PSORS1C2 PTHR31853:SF1 PSORIASIS SUSCEPTIBILITY 1 CANDIDATE GENE 2 PROTEIN PSORIASIS SUSCEPTIBILITY 1 CANDIDATE GENE 2 PROTEIN GORGO|Ensembl=ENSGGOG00000002279.3|UniProtKB=A0A2I2YLA7 A0A2I2YLA7 GRIP2 PTHR46227:SF4 GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP GLUTAMATE RECEPTOR-INTERACTING PROTEIN 2 cellular process#GO:0009987;endosome to plasma membrane protein transport#GO:0099638;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;protein localization to cell periphery#GO:1990778;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;protein localization to synapse#GO:0035418;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;endocytic recycling#GO:0032456;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;protein localization to cell junction#GO:1902414;regulation of biological quality#GO:0065008;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179 GORGO|Ensembl=ENSGGOG00000010669.3|UniProtKB=G3RSC0 G3RSC0 SMOX PTHR10742:SF416 FLAVIN MONOAMINE OXIDASE SPERMINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 amine catabolic process#GO:0009310;metabolic process#GO:0008152;polyamine catabolic process#GO:0006598;biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;amine metabolic process#GO:0009308 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000008099.3|UniProtKB=A0A2I2YK07 A0A2I2YK07 PTHR13045:SF13 5'-NUCLEOTIDASE 5'-NUCLEOTIDASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 esterase#PC00097;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000816.3|UniProtKB=G3QEV3 G3QEV3 ADAMTS2 PTHR13723:SF141 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 2 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000027917.2|UniProtKB=G3RR83 G3RR83 PTHR23339:SF117 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14C phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 regulation of cell cycle#GO:0051726;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;regulation of mitotic cell cycle phase transition#GO:1901990;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;positive regulation of cell cycle#GO:0045787;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002049.3|UniProtKB=G3QI19 G3QI19 OR52D1 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010809.3|UniProtKB=G3SD55 G3SD55 CD33 PTHR12035:SF132 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN MYELOID CELL SURFACE ANTIGEN CD33 organic acid binding#GO:0043177;ion binding#GO:0043167;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;binding#GO:0005488 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000001846.3|UniProtKB=G3SAB1 G3SAB1 HES2 PTHR10985:SF15 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 GORGO|Ensembl=ENSGGOG00000002888.3|UniProtKB=G3QK71 G3QK71 VWA2 PTHR24020:SF37 COLLAGEN ALPHA VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 2 cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000039793.1|UniProtKB=A0A2I2Z715 A0A2I2Z715 LOC101145021 PTHR48018:SF61 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B2-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003598.3|UniProtKB=G3S359 G3S359 LRRC38 PTHR24366:SF61 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 52 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000013886.3|UniProtKB=G3RDF4 G3RDF4 ADAM15 PTHR11905:SF130 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 15 cell adhesion molecule binding#GO:0050839;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;integrin binding#GO:0005178;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;hydrolase activity#GO:0016787 cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;immune system process#GO:0002376;proteolysis#GO:0006508;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;integrin-mediated signaling pathway#GO:0007229;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000009137.3|UniProtKB=G3R181 G3R181 CERS5 PTHR12560:SF8 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000042980.1|UniProtKB=A0A2I2ZL04 A0A2I2ZL04 PTHR21357:SF2 FAM172 FAMILY PROTEIN HOMOLOG CG10038 PROTEIN ARB2BP-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulatory ncRNA-mediated heterochromatin formation#GO:0031048 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007871.3|UniProtKB=G3QXX4 G3QXX4 LCN9 PTHR11430:SF28 LIPOCALIN EPIDIDYMAL-SPECIFIC LIPOCALIN-9 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000001370.3|UniProtKB=G3QGA0 G3QGA0 PTCRA PTHR37866:SF1 PRE T-CELL ANTIGEN RECEPTOR ALPHA PRE T-CELL ANTIGEN RECEPTOR ALPHA regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000001861.4|UniProtKB=G3QHK4 G3QHK4 SLC30A9 PTHR13414:SF9 HUEL-CATION TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A9, MITOCHONDRIAL monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;zinc ion transport#GO:0006829;monoatomic ion homeostasis#GO:0050801 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000039255.1|UniProtKB=G3QYR4 G3QYR4 MTARC1 PTHR14237:SF25 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MITOCHONDRIAL AMIDOXIME-REDUCING COMPONENT 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;nitrate metabolic process#GO:0042126;small molecule metabolic process#GO:0044281 GORGO|Ensembl=ENSGGOG00000009555.3|UniProtKB=G3R289 G3R289 ZKSCAN5 PTHR23226:SF464 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000000602.3|UniProtKB=G3QEA1 G3QEA1 PTHR15348:SF1 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000002277.3|UniProtKB=G3QIM6 G3QIM6 DXO PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;RNA decapping#GO:0110154;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000001894.3|UniProtKB=G3QHP6 G3QHP6 VPS13D PTHR16166:SF141 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13D transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014 cellular component organization#GO:0016043;catabolic process#GO:0009056;lipid localization#GO:0010876;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;autophagy#GO:0006914;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;macroautophagy#GO:0016236;lipid transport#GO:0006869;transport#GO:0006810;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;mitochondrion#GO:0005739;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000028458.2|UniProtKB=G3SF24 G3SF24 PTHR11850:SF389 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000000441.3|UniProtKB=G3QDV5 G3QDV5 HACD2 PTHR11035:SF17 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 2 catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000013243.3|UniProtKB=G3S9P9 G3S9P9 PAFAH1B3 PTHR11852:SF2 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT ALPHA1 acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;transferase activity#GO:0016740;hydrolase activity, acting on ester bonds#GO:0016788;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276;developmental process involved in reproduction#GO:0003006 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003484.3|UniProtKB=G3RNQ8 G3RNQ8 SHCBP1L PTHR14695:SF7 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED TESTICULAR SPINDLE-ASSOCIATED PROTEIN SHCBP1L meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;spermatogenesis#GO:0007283;meiotic cell cycle#GO:0051321;male meiotic nuclear division#GO:0007140;male gamete generation#GO:0048232;cellular process#GO:0009987;organelle organization#GO:0006996;multicellular organismal reproductive process#GO:0048609;organelle fission#GO:0048285;cytoskeleton-dependent cytokinesis#GO:0061640;sexual reproduction#GO:0019953;cytokinesis#GO:0000910;nuclear division#GO:0000280;reproductive process#GO:0022414;gamete generation#GO:0007276;cell cycle process#GO:0022402;cell division#GO:0051301;cellular component organization#GO:0016043;developmental process involved in reproduction#GO:0003006;meiotic cell cycle process#GO:1903046;cell cycle#GO:0007049 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000016604.3|UniProtKB=G3RKD1 G3RKD1 KICS2 PTHR31581:SF1 KICSTOR COMPLEX PROTEIN C12ORF66 KICSTOR SUBUNIT 2 cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;intracellular protein localization#GO:0008104;response to nutrient levels#GO:0031667;macromolecule localization#GO:0033036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;protein localization to vacuole#GO:0072665;localization#GO:0051179;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;negative regulation of TORC1 signaling#GO:1904262;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;protein localization to lysosome#GO:0061462;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000000842.3|UniProtKB=G3QEX3 G3QEX3 C11H2orf76 PTHR18444:SF9 UPF0538 FAMILY MEMBER UPF0538 PROTEIN C2ORF76 GORGO|Ensembl=ENSGGOG00000002833.3|UniProtKB=G3QK26 G3QK26 ZC3H3 PTHR46156:SF1 CCCH ZINGC FINGER ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000002393.3|UniProtKB=G3QIY3 G3QIY3 PYCR3 PTHR11645:SF72 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE 3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 reductase#PC00198;metabolite interconversion enzyme#PC00262 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 GORGO|Ensembl=ENSGGOG00000003979.3|UniProtKB=G3QN03 G3QN03 LIPA PTHR11005:SF26 LYSOSOMAL ACID LIPASE-RELATED LYSOSOMAL ACID LIPASE_CHOLESTERYL ESTER HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 hydrolase#PC00121;lipase#PC00143 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol esterase#P02830 GORGO|Ensembl=ENSGGOG00000015396.3|UniProtKB=G3RHA4 G3RHA4 LRRIQ4 PTHR48051:SF28 FAMILY NOT NAMED LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 4 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000039156.1|UniProtKB=A0A2I2Z2T1 A0A2I2Z2T1 LIPI PTHR11610:SF103 LIPASE LIPASE MEMBER I glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 GORGO|Ensembl=ENSGGOG00000000702.3|UniProtKB=G3QEJ4 G3QEJ4 KPTN PTHR15435:SF2 KICSTOR COMPLEX PROTEIN KAPTIN KICSTOR COMPLEX PROTEIN KAPTIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;negative regulation of response to stimulus#GO:0048585;cellular response to amino acid starvation#GO:0034198;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to stress#GO:0006950;response to nutrient levels#GO:0031667;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262;cellular response to nutrient levels#GO:0031669 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;cell leading edge#GO:0031252 GORGO|Ensembl=ENSGGOG00000007332.3|UniProtKB=G3QWM0 G3QWM0 BMAL2 PTHR23042:SF48 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS BASIC HELIX-LOOP-HELIX ARNT-LIKE PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000023435.2|UniProtKB=G3SBQ8 G3SBQ8 RAB33A PTHR47978:SF30 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33A ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 organelle assembly#GO:0070925;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;catabolic process#GO:0009056;cellular component assembly#GO:0022607;macroautophagy#GO:0016236 endosome#GO:0005768;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000003768.3|UniProtKB=G3QMG0 G3QMG0 STON2 PTHR10529:SF345 AP COMPLEX SUBUNIT MU STONIN-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 synaptic vesicle cycle#GO:0099504;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;regulation of endocytosis#GO:0030100;intracellular transport#GO:0046907;regulation of localization#GO:0032879;receptor-mediated endocytosis#GO:0006898;regulation of transport#GO:0051049;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;post-Golgi vesicle-mediated transport#GO:0006892;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641;localization#GO:0051179;clathrin-dependent endocytosis#GO:0072583;regulation of biological process#GO:0050789;synaptic vesicle endocytosis#GO:0048488;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of cellular component organization#GO:0051128 endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane#GO:0005886;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;cytosol#GO:0005829;cell periphery#GO:0071944;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;synaptic vesicle#GO:0008021;vesicle#GO:0031982;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;vesicle coat#GO:0030120;secretory vesicle#GO:0099503;presynapse#GO:0098793;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin vesicle coat#GO:0030125;cellular anatomical structure#GO:0110165;synapse#GO:0045202;clathrin coat#GO:0030118;organelle#GO:0043226;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;coated membrane#GO:0048475;coated vesicle#GO:0030135;endocytic vesicle#GO:0030139;organelle subcompartment#GO:0031984;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000002560.3|UniProtKB=G3QJD3 G3QJD3 SEC63 PTHR24075:SF0 SEC63 DOMAIN-CONTAINING TRANSLOCATION PROTEIN SEC63 HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;protein targeting to ER#GO:0045047;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000036367.1|UniProtKB=A0A2I2Z9J2 A0A2I2Z9J2 PTHR11783:SF48 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1 FAMILY MEMBER D1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012397.3|UniProtKB=G3R9K8 G3R9K8 RPP25 PTHR13516:SF5 RIBONUCLEASE P SUBUNIT P25 RIBONUCLEASE P PROTEIN SUBUNIT P25 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular protein-containing complex#GO:0140535;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000014224.3|UniProtKB=G3RE94 G3RE94 ENDOG PTHR13966:SF5 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;programmed cell death#GO:0012501;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;catabolic process#GO:0009056 cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Apoptosis signaling pathway#P00006>endoG#P00279 GORGO|Ensembl=ENSGGOG00000037349.1|UniProtKB=A0A2I2YYD9 A0A2I2YYD9 CHCHD3 PTHR21588:SF20 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 3 cellular component organization or biogenesis#GO:0071840;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;membrane organization#GO:0061024 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000014871.3|UniProtKB=A0A2I2YL54 A0A2I2YL54 MRPS22 PTHR13071:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S22 SMALL RIBOSOMAL SUBUNIT PROTEIN MS22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008150.3|UniProtKB=G3QYM9 G3QYM9 NDUFAF6 PTHR21181:SF13 ER membrane protein complex subunit 5-related NADH DEHYDROGENASE (UBIQUINONE) COMPLEX I, ASSEMBLY FACTOR 6 GORGO|Ensembl=ENSGGOG00000006299.3|UniProtKB=G3QTX5 G3QTX5 RSPH9 PTHR22069:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN S18 RADIAL SPOKE HEAD PROTEIN 9 HOMOLOG cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226 intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;axoneme#GO:0005930;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000039920.1|UniProtKB=A0A2I2Y645 A0A2I2Y645 PTHR23232:SF67 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 738 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005135.3|UniProtKB=G3QR01 G3QR01 PAQR4 PTHR20855:SF138 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003897.3|UniProtKB=G3QMS7 G3QMS7 C18H16orf86 PTHR37867:SF1 CHROMOSOME 16 OPEN READING FRAME 86 CHROMOSOME 18 C16ORF86 HOMOLOG GORGO|Ensembl=ENSGGOG00000026200.2|UniProtKB=G3S9N8 G3S9N8 FEZF2 PTHR24381:SF481 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013768.3|UniProtKB=A0A2I2YLC8 A0A2I2YLC8 CNKSR2 PTHR12844:SF21 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 synapse organization#GO:0050808;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;postsynaptic specialization organization#GO:0099084;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;signaling#GO:0023052;postsynapse organization#GO:0099173;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000043933.1|UniProtKB=G3SED4 G3SED4 PABPC1L2A PTHR24012:SF848 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1-LIKE 2 mRNA 3'-UTR binding#GO:0003730;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;mRNA binding#GO:0003729 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cytosol#GO:0005829;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000043428.1|UniProtKB=A0A2I2ZF49 A0A2I2ZF49 PTHR12794:SF5 GEMIN2 GEM-ASSOCIATED PROTEIN 2 cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 intracellular organelle#GO:0043229;Sm-like protein family complex#GO:0120114;SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000004915.3|UniProtKB=G3RH22 G3RH22 LOC101139056 PTHR22950:SF258 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 3 monoatomic cation transmembrane transporter activity#GO:0008324;solute:proton symporter activity#GO:0015295;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;glycine transmembrane transporter activity#GO:0015187;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;amino acid transmembrane transporter activity#GO:0015171;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;neutral L-amino acid transmembrane transporter activity#GO:0015175 carboxylic acid transmembrane transport#GO:1905039;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;alanine transport#GO:0032328;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 amino acid transporter#PC00046;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000005205.3|UniProtKB=A0A2I2YMN4 A0A2I2YMN4 GFPT1 PTHR10937:SF12 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 UDP-N-acetylglucosamine biosynthetic process#GO:0006048;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225 transaminase#PC00216 O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042 GORGO|Ensembl=ENSGGOG00000002744.3|UniProtKB=A0A2I2YKP4 A0A2I2YKP4 TMPRSS13 PTHR24253:SF55 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 13 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000022920.2|UniProtKB=A0A2I2Y6G2 A0A2I2Y6G2 BAIAP2L1 PTHR14206:SF4 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BAR_IMD DOMAIN-CONTAINING ADAPTER PROTEIN 2-LIKE 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;actin filament bundle assembly#GO:0051017;regulation of supramolecular fiber organization#GO:1902903;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;actin filament bundle organization#GO:0061572;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016791.4|UniProtKB=G3RKV4 G3RKV4 HCLS1 PTHR10829:SF5 CORTACTIN AND DREBRIN HEMATOPOIETIC LINEAGE CELL-SPECIFIC PROTEIN cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament polymerization#GO:0030833;cell migration#GO:0016477;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;regulation of cellular component biogenesis#GO:0044087;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cell periphery#GO:0071944;membrane#GO:0016020;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000041697.1|UniProtKB=A0A2I2YN92 A0A2I2YN92 PTHR23232:SF148 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016445.3|UniProtKB=G3RJY9 G3RJY9 ZNF777 PTHR24381:SF261 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 777 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006948.3|UniProtKB=A0A2I2ZBP3 A0A2I2ZBP3 GBF1 PTHR10663:SF412 GUANYL-NUCLEOTIDE EXCHANGE FACTOR GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi cis cisterna#GO:0000137;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000006750.3|UniProtKB=G3QV41 G3QV41 CPLX4 PTHR16705:SF7 COMPLEXIN COMPLEXIN-4 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;neurotransmitter transport#GO:0006836;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;regulation of localization#GO:0032879;regulation of transport#GO:0051049;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055;export from cell#GO:0140352;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of signaling#GO:0023051 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;presynapse#GO:0098793;neuron projection#GO:0043005;membrane#GO:0016020;axon terminus#GO:0043679;cell junction#GO:0030054;neuron projection terminus#GO:0044306;cell projection#GO:0042995;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;axon#GO:0030424 GORGO|Ensembl=ENSGGOG00000005629.3|UniProtKB=G3QS81 G3QS81 CHKB PTHR22603:SF35 CHOLINE/ETHANOALAMINE KINASE CHOLINE_ETHANOLAMINE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000003071.3|UniProtKB=G3QKP3 G3QKP3 TMEM63B PTHR13018:SF38 PROBABLE MEMBRANE PROTEIN DUF221-RELATED MECHANOSENSITIVE CATION CHANNEL TMEM63B transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion-gated channel activity#GO:0022839;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000011048.3|UniProtKB=G3R631 G3R631 SH2D3C PTHR14247:SF6 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 3C GORGO|Ensembl=ENSGGOG00000026541.2|UniProtKB=G3S0W4 G3S0W4 LRRN3 PTHR24366:SF73 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT NEURONAL PROTEIN 3 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000011439.3|UniProtKB=G3R729 G3R729 CCT6A PTHR11353:SF54 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ZETA primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chaperonin#PC00073 GORGO|Gene=ST7|UniProtKB=Q2IBE8 Q2IBE8 ST7 PTHR12745:SF10 SUPPRESSION OF TUMORIGENICITY 7 SUPPRESSOR OF TUMORIGENICITY 7 PROTEIN GORGO|Ensembl=ENSGGOG00000026644.2|UniProtKB=G3SGF3 G3SGF3 AK4 PTHR23359:SF58 NUCLEOTIDE KINASE ADENYLATE KINASE 4, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550 nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 GORGO|Ensembl=ENSGGOG00000028522.2|UniProtKB=G3RNK5 G3RNK5 PRMT6 PTHR11006:SF73 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 6 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015780.3|UniProtKB=G3S6N6 G3S6N6 FOXI1 PTHR11829:SF180 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000004452.3|UniProtKB=A0A2I2YW87 A0A2I2YW87 SLC13A3 PTHR10283:SF62 SOLUTE CARRIER FAMILY 13 MEMBER NA(+)_DICARBOXYLATE COTRANSPORTER 3 transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;succinate transmembrane transporter activity#GO:0015141;solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;citrate transmembrane transporter activity#GO:0015137;monoatomic cation transmembrane transporter activity#GO:0008324;sodium:dicarboxylate symporter activity#GO:0017153 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;tricarboxylic acid transport#GO:0006842;transport#GO:0006810;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;citrate transport#GO:0015746;carboxylic acid transmembrane transport#GO:1905039;dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000008253.3|UniProtKB=G3QYX3 G3QYX3 SLC22A18 PTHR24002:SF5 SOLUTE CARRIER FAMILY 22 MEMBER 18 SOLUTE CARRIER FAMILY 67 MEMBER A1 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;xenobiotic transport#GO:0042908;export from cell#GO:0140352;detoxification#GO:0098754;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to toxic substance#GO:0009636;cellular process#GO:0009987;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000022726.2|UniProtKB=G3S2X7 G3S2X7 ABCE1 PTHR19248:SF32 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY E MEMBER 1 ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;ribonucleoprotein complex binding#GO:0043021;cation binding#GO:0043169;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;metal ion binding#GO:0046872;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;iron ion binding#GO:0005506 gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;translational termination#GO:0006415;translation#GO:0006412;translational initiation#GO:0006413 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000012673.3|UniProtKB=G3RAA1 G3RAA1 GRIA2 PTHR18966:SF99 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 2 channel activity#GO:0015267;molecular transducer activity#GO:0060089;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171 anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;cellular process#GO:0009987 signaling receptor complex#GO:0043235;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;dendrite#GO:0030425;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;neuron projection#GO:0043005;protein-containing complex#GO:0032991;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynapse#GO:0098794;dendritic spine#GO:0043197;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuron spine#GO:0044309 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu2#P01017;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 GORGO|Ensembl=ENSGGOG00000025150.2|UniProtKB=G3RV10 G3RV10 LOC101138014 PTHR48002:SF146 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4X2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000036787.1|UniProtKB=A0A2I2Z5W9 A0A2I2Z5W9 PTHR16206:SF13 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016982.3|UniProtKB=A0A2I2ZG39 A0A2I2ZG39 JADE2 PTHR13793:SF84 PHD FINGER PROTEINS E3 UBIQUITIN-PROTEIN LIGASE JADE-2 histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000014014.3|UniProtKB=G3RDQ7 G3RDQ7 NAAA PTHR28583:SF4 ACID AMIDASE N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000022760.2|UniProtKB=G3RSP5 G3RSP5 MRPL42 PTHR13450:SF4 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L42 LARGE RIBOSOMAL SUBUNIT PROTEIN ML42 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000015775.3|UniProtKB=G3RQQ4 G3RQQ4 ZNF341 PTHR24388:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 341 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000003988.3|UniProtKB=G3QN10 G3QN10 SNRPN PTHR14508:SF3 SNRPN UPSTREAM READING FRAME PROTEIN, SNURF SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN GORGO|Ensembl=ENSGGOG00000014698.3|UniProtKB=G3RFG9 G3RFG9 RNF24 PTHR22763:SF192 RING ZINC FINGER PROTEIN RING-TYPE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008062.3|UniProtKB=A0A2I2Z894 A0A2I2Z894 TOX2 PTHR45781:SF5 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 2 binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000003989.3|UniProtKB=G3RWC4 G3RWC4 FADD PTHR15077:SF9 FAS-ASSOCIATING DEATH DOMAIN-CONTAINING PROTEIN FADD FAS-ASSOCIATED DEATH DOMAIN PROTEIN Apoptosis signaling pathway#P00006>FADD#P00327;FAS signaling pathway#P00020>FADD#P00622 GORGO|Ensembl=ENSGGOG00000027324.2|UniProtKB=G3SCR0 G3SCR0 CA2 PTHR18952:SF120 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 2 hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;biological regulation#GO:0065007 membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000006904.3|UniProtKB=G3QVJ2 G3QVJ2 COL23A1 PTHR24023:SF995 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000001460.3|UniProtKB=G3QGI3 G3QGI3 ABHD11 PTHR46118:SF4 PROTEIN ABHD11 SN-1-SPECIFIC DIACYLGLYCEROL LIPASE ABHD11 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000043312.1|UniProtKB=G3RL02 G3RL02 KRT34 PTHR23239:SF165 INTERMEDIATE FILAMENT IF ROD DOMAIN-CONTAINING PROTEIN-RELATED structural molecule activity#GO:0005198 intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;developmental process#GO:0032502;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000014137.3|UniProtKB=G3RTQ7 G3RTQ7 UMPS PTHR19278:SF9 OROTATE PHOSPHORIBOSYLTRANSFERASE URIDINE 5'-MONOPHOSPHATE SYNTHASE lyase activity#GO:0016829;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;pyrimidine nucleobase metabolic process#GO:0006206;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086 transferase#PC00220;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Orotate phosphoribosyltransferase#P02922 GORGO|Ensembl=ENSGGOG00000026783.2|UniProtKB=A0A2I2YG02 A0A2I2YG02 LOC101154163 PTHR15592:SF26 MATRIN 3/NUCLEAR PROTEIN 220-RELATED RRM DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of cell differentiation#GO:0045595;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000013153.3|UniProtKB=G3RBH4 G3RBH4 PSMD13 PTHR10539:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular protein-containing complex#GO:0140535;proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;protein modifying enzyme#PC00260 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Parkinson disease#P00049>19S proteasome#P01209 GORGO|Ensembl=ENSGGOG00000004898.3|UniProtKB=G3QQD6 G3QQD6 TUBE1 PTHR11588:SF317 TUBULIN TUBULIN EPSILON CHAIN guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166 mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 GORGO|Ensembl=ENSGGOG00000000706.3|UniProtKB=G3QEJ8 G3QEJ8 RXYLT1 PTHR15576:SF1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763 protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003023.3|UniProtKB=G3QKJ7 G3QKJ7 IL4R PTHR23037:SF32 CYTOKINE RECEPTOR INTERLEUKIN-4 RECEPTOR SUBUNIT ALPHA transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000028303.2|UniProtKB=A0A2I2YU35 A0A2I2YU35 LOC101133170 PTHR12035:SF109 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 14 organic acid binding#GO:0043177;ion binding#GO:0043167;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000036596.1|UniProtKB=A0A2I2YPE0 A0A2I2YPE0 LOC109025290 PTHR19970:SF39 RIBOSOMAL PROTEIN L39E RIBOSOMAL PROTEIN L39 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000001096.3|UniProtKB=G3QFK4 G3QFK4 ATOH1 PTHR19290:SF82 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000015872.3|UniProtKB=G3RIH7 G3RIH7 POLR1G PTHR15484:SF8 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA34 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA34 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005338.3|UniProtKB=G3QRH5 G3QRH5 SRRM4 PTHR34755:SF1 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE_ARGININE REPETITIVE MATRIX PROTEIN 4 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nervous system development#GO:0007399;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;mRNA metabolic process#GO:0016071;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;nucleic acid biosynthetic process#GO:0141187;generation of neurons#GO:0048699;RNA metabolic process#GO:0016070;neuron development#GO:0048666;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;developmental process#GO:0032502;cell maturation#GO:0048469;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;anatomical structure maturation#GO:0071695;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;anatomical structure development#GO:0048856;system development#GO:0048731 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008175.3|UniProtKB=G3QYQ0 G3QYQ0 TMEM38A PTHR12454:SF3 TRIMERIC INTRACELLULAR CATION CHANNEL TRIMERIC INTRACELLULAR CATION CHANNEL TYPE A potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873 transport#GO:0006810;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;cytoplasm#GO:0005737;sarcoplasmic reticulum membrane#GO:0033017;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000014626.3|UniProtKB=A0A2I2YD65 A0A2I2YD65 VCF1 PTHR34763:SF1 PROTEIN FAM104A PROTEIN VCF1 GORGO|Ensembl=ENSGGOG00000039014.1|UniProtKB=A0A2I2YLV9 A0A2I2YLV9 PTHR12280:SF37 PANTOTHENATE KINASE PANTOTHENATE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006848.4|UniProtKB=G3QVD9 G3QVD9 DNAJC11 PTHR44157:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000016817.4|UniProtKB=G3RKX5 G3RKX5 CDH12 PTHR24027:SF96 CADHERIN-23 CADHERIN-12 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular component assembly#GO:0022607;cell migration#GO:0016477;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330 extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000000380.3|UniProtKB=G3QDP8 G3QDP8 IL20RA PTHR20859:SF86 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-20 RECEPTOR SUBUNIT ALPHA transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375 response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000043851.1|UniProtKB=G3QMQ8 G3QMQ8 ZNF253 PTHR24384:SF181 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 253 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013468.3|UniProtKB=G3RCB5 G3RCB5 TBX15 PTHR11267:SF98 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX15 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 GORGO|Ensembl=ENSGGOG00000041967.1|UniProtKB=A0A2I2Z3N7 A0A2I2Z3N7 PTHR15591:SF16 RUN AND SH3 DOMAIN CONTAINING FARNESYL PYROPHOSPHATE SYNTHASE intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000003499.3|UniProtKB=G3QLS2 G3QLS2 KPRP PTHR48148:SF2 KERATINOCYTE PROLINE-RICH PROTEIN KERATINOCYTE PROLINE-RICH PROTEIN GORGO|Ensembl=ENSGGOG00000040112.1|UniProtKB=A0A2I2ZHZ6 A0A2I2ZHZ6 ROMO1 PTHR28525:SF1 REACTIVE OXYGEN SPECIES MODULATOR 1 REACTIVE OXYGEN SPECIES MODULATOR 1 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein insertion into mitochondrial inner membrane#GO:0045039;membrane organization#GO:0061024;mitochondrial protein import pathway#GO:7770058;mitochondrion organization#GO:0007005;protein import into mitochondrial matrix#GO:0030150;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;macromolecule localization#GO:0033036;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000044212.1|UniProtKB=G3R4L8 G3R4L8 EXOSC4 PTHR11953:SF0 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP41 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA catabolic process#GO:0006401;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056 catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000002712.3|UniProtKB=G3QJS1 G3QJS1 ZNHIT2 PTHR15555:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 2 PROTEIN FON -RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000041018.1|UniProtKB=A0A2I2ZMB9 A0A2I2ZMB9 PTHR21533:SF23 LEUCINE-RICH PROTEIN CHIBBY FAMILY MEMBER 1, BETA CATENIN ANTAGONIST negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005927.3|UniProtKB=G3QSZ9 G3QSZ9 JADE3 PTHR13793:SF27 PHD FINGER PROTEINS PROTEIN JADE-3 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000015169.3|UniProtKB=G3RGQ0 G3RGQ0 SGSM3 PTHR22957:SF681 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 3 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000013529.3|UniProtKB=G3RCH2 G3RCH2 FA2H PTHR12863:SF23 FATTY ACID HYDROXYLASE FATTY ACID 2-HYDROXYLASE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 nervous system development#GO:0007399;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;lipid biosynthetic process#GO:0008610;oligodendrocyte differentiation#GO:0048709;cellular process#GO:0009987;neurogenesis#GO:0022008;myelination#GO:0042552;gliogenesis#GO:0042063;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;lipid metabolic process#GO:0006629;developmental process#GO:0032502;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;cell development#GO:0048468;central nervous system development#GO:0007417;cell differentiation#GO:0030154;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;system development#GO:0048731;anatomical structure development#GO:0048856;ceramide metabolic process#GO:0006672;plasma membrane organization#GO:0007009;animal gross anatomical part developmental process#GO:0160108 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 oxidoreductase#PC00176;hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000015178.3|UniProtKB=A0A2I2Z7C4 A0A2I2Z7C4 MCTP1 PTHR45911:SF3 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;regulation of secretion by cell#GO:1903530;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of secretion#GO:0051046;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter secretion#GO:0046928;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794 vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;cytoplasm#GO:0005737;cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000012162.3|UniProtKB=G3R8Z9 G3R8Z9 PTHR10404:SF33 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE TRANSFERRIN RECEPTOR PROTEIN 2 catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000012765.3|UniProtKB=G3RAI1 G3RAI1 SOX13 PTHR45789:SF4 FI18025P1 TRANSCRIPTION FACTOR SOX-13 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000036919.1|UniProtKB=A0A2I2Y886 A0A2I2Y886 LOC109028639 PTHR23288:SF36 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCEL DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676 gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;snRNA transcription#GO:0009301;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;transcription by RNA polymerase II#GO:0006366;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000002867.3|UniProtKB=G3QK52 G3QK52 AURKB PTHR24350:SF4 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE B catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule cytoskeleton organization#GO:0000226;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 kinetochore#GO:0000776;midbody#GO:0030496;chromosome#GO:0005694;spindle pole#GO:0000922;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;spindle midzone#GO:0051233;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000041768.1|UniProtKB=A0A2I2YZD5 A0A2I2YZD5 PRR15 PTHR14581:SF4 FAMILY NOT NAMED PROLINE-RICH PROTEIN 15 GORGO|Ensembl=ENSGGOG00000013670.3|UniProtKB=G3RCU9 G3RCU9 CCDC86 PTHR13557:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000023846.2|UniProtKB=G3RS36 G3RS36 JCHAIN PTHR10070:SF2 IMMUNOGLOBULIN J CHAIN IMMUNOGLOBULIN J CHAIN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 immune system process#GO:0002376;humoral immune response#GO:0006959;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000006957.3|UniProtKB=G3QVM6 G3QVM6 GMFG PTHR11249:SF4 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR GAMMA protein-containing complex binding#GO:0044877;binding#GO:0005488 negative regulation of cytoskeleton organization#GO:0051494;actin filament-based process#GO:0030029;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of actin nucleation#GO:0051125;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000042455.1|UniProtKB=A0A2I2ZXW7 A0A2I2ZXW7 LRATD2 PTHR46341:SF2 PROTEIN FAM84B-RELATED PROTEIN LRATD2 GORGO|Ensembl=ENSGGOG00000014073.4|UniProtKB=G3RDX8 G3RDX8 PTHR10887:SF5 DNA2/NAM7 HELICASE FAMILY RNA HELICASE AQUARIUS nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000006909.3|UniProtKB=G3QVI7 G3QVI7 SPATA24 PTHR35155:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 24 SPERMATOGENESIS-ASSOCIATED PROTEIN 24 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000012610.3|UniProtKB=A0A2I2Y6N8 A0A2I2Y6N8 HINT3 PTHR12486:SF5 APRATAXIN-RELATED ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000012063.3|UniProtKB=A0A2I2YIZ7 A0A2I2YIZ7 LEMD1 PTHR12019:SF12 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN LEM DOMAIN-CONTAINING PROTEIN 1 intercellular signal molecule#PC00207;peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000015263.3|UniProtKB=G3RGY3 G3RGY3 RCC2 PTHR46207:SF1 PROTEIN RCC2 PROTEIN RCC2 enzyme binding#GO:0019899;binding#GO:0005488;small GTPase binding#GO:0031267;protein binding#GO:0005515 regulation of chromosome segregation#GO:0051983;intracellular protein localization#GO:0008104;localization#GO:0051179;positive regulation of cellular process#GO:0048522;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;macromolecule localization#GO:0033036;protein localization to kinetochore#GO:0034501;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010385.3|UniProtKB=G3SA07 G3SA07 SCTR PTHR45620:SF13 PDF RECEPTOR-LIKE PROTEIN-RELATED SECRETIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000038451.1|UniProtKB=G3QVI4 G3QVI4 LOC101132628 PTHR11596:SF69 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE, PLACENTAL TYPE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000001537.2|UniProtKB=G3QGQ5 G3QGQ5 SF3B5 PTHR20978:SF0 SPLICING FACTOR 3B SUBUNIT 5 SPLICING FACTOR 3B SUBUNIT 5 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000003873.3|UniProtKB=G3QMQ7 G3QMQ7 KRT78 PTHR45616:SF18 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 78 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epidermis development#GO:0008544;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869 supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000012172.3|UniProtKB=G3R901 G3R901 YIPF4 PTHR21236:SF7 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF4 cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043;Golgi organization#GO:0007030;vesicle fusion#GO:0006906;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;endomembrane system organization#GO:0010256 Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000042829.1|UniProtKB=G3SDV8 G3SDV8 PTHR19256:SF70 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 2 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000006433.3|UniProtKB=G3QU92 G3QU92 LOC101152645 PTHR44427:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000000821.3|UniProtKB=G3QEV7 G3QEV7 DNAJC8 PTHR15606:SF7 DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 8 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000036276.1|UniProtKB=A0A2I2YAN4 A0A2I2YAN4 IYD PTHR23026:SF128 NADPH NITROREDUCTASE IODOTYROSINE DEIODINASE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 regulation of biological quality#GO:0065008;metabolic process#GO:0008152;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;modified amino acid metabolic process#GO:0006575 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 reductase#PC00198;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012456.3|UniProtKB=A0A2I2Z4X0 A0A2I2Z4X0 PARP3 PTHR10459:SF66 DNA LIGASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP3 catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;site of double-strand break#GO:0035861 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 GORGO|Ensembl=ENSGGOG00000005465.3|UniProtKB=G3QRT7 G3QRT7 CDX4 PTHR24332:SF15 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-4 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;anterior/posterior axis specification#GO:0009948;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;tube development#GO:0035295;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;embryonic pattern specification#GO:0009880;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000028270.2|UniProtKB=A0A2I2Z7D4 A0A2I2Z7D4 PTHR11830:SF24 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000036762.1|UniProtKB=A0A2I2YGX9 A0A2I2YGX9 ZNF892 PTHR24399:SF86 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER PROTEIN 892 sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000014223.3|UniProtKB=G3REA3 G3REA3 CPED1 PTHR14776:SF1 CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1 CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000010217.3|UniProtKB=G3S2T0 G3S2T0 ZNF77 PTHR24379:SF143 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 77 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000043062.1|UniProtKB=A0A2I2YNY0 A0A2I2YNY0 LOC115930162 PTHR24264:SF62 TRYPSIN-RELATED TRYPSIN catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000006674.3|UniProtKB=G3QUX1 G3QUX1 RPAP2 PTHR14732:SF0 RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA transcription#GO:0009301 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000014515.3|UniProtKB=G3RT36 G3RT36 BRD3 PTHR22880:SF246 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 3 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000026807.2|UniProtKB=G3RQZ6 G3RQZ6 TMPRSS5 PTHR24253:SF70 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 5 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000010639.3|UniProtKB=G3R515 G3R515 PRKCI PTHR24356:SF214 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C IOTA TYPE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 macromolecule localization#GO:0033036;cellular response to nitrogen compound#GO:1901699;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to insulin stimulus#GO:0032869;intracellular protein localization#GO:0008104;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;establishment of cell polarity#GO:0030010;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;localization within membrane#GO:0051668;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;protein localization to cell periphery#GO:1990778;response to endogenous stimulus#GO:0009719;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;establishment or maintenance of cell polarity#GO:0007163;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular localization#GO:0051641 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Endothelin signaling pathway#P00019>PKC#P00568;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458 GORGO|Ensembl=ENSGGOG00000026492.2|UniProtKB=G3S028 G3S028 PGRMC2 PTHR10281:SF24 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 2 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006707.3|UniProtKB=G3QV01 G3QV01 MGST1 PTHR10689:SF11 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000008422.3|UniProtKB=G3QZC3 G3QZC3 ALG10B PTHR12989:SF11 ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10 DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE A hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009975.3|UniProtKB=G3R3B0 G3R3B0 ZMAT3 PTHR46786:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 3 ZINC FINGER MATRIN-TYPE PROTEIN 3 RNA metabolism protein#PC00031;RNA processing factor#PC00147 p53 pathway#P00059>PAG608#G04690 GORGO|Ensembl=ENSGGOG00000021998.2|UniProtKB=A0A2I2Y3R2 A0A2I2Y3R2 PTHR16520:SF3 KINETOCHORE SCAFFOLD 1 OUTER KINETOCHORE KNL1 COMPLEX SUBUNIT KNL1 nuclear chromosome segregation#GO:0098813;attachment of spindle microtubules to kinetochore#GO:0008608;protein localization to kinetochore#GO:0034501;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;protein localization to organelle#GO:0033365;chromosome localization#GO:0050000;organelle localization#GO:0051640;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;localization#GO:0051179;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001754.3|UniProtKB=A0A2I2YXT0 A0A2I2YXT0 ITGB1BP1 PTHR32055:SF1 INTEGRIN BETA-1-BINDING PROTEIN 1 INTEGRIN BETA-1-BINDING PROTEIN 1 protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;regulation of cellular component organization#GO:0051128;negative regulation of cell adhesion#GO:0007162;regulation of cellular component biogenesis#GO:0044087;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of cell junction assembly#GO:1901888;regulation of cell-matrix adhesion#GO:0001952 membraneless organelle#GO:0043228;ruffle#GO:0001726;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lamellipodium#GO:0030027;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cell leading edge#GO:0031252;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000014618.3|UniProtKB=G3RF92 G3RF92 OR4N2 PTHR26453:SF634 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000028429.2|UniProtKB=G3S9Y6 G3S9Y6 PTHR10438:SF378 THIOREDOXIN THIOREDOXIN catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035 cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009384.3|UniProtKB=G3R1U8 G3R1U8 SPTB PTHR11915:SF248 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, ERYTHROCYTIC binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000040685.1|UniProtKB=A0A2I2ZFY3 A0A2I2ZFY3 LOC101137406 PTHR11639:SF146 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A7A ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular process#GO:0009987;cell migration#GO:0016477;endothelial cell migration#GO:0043542;cell motility#GO:0048870 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000027270.2|UniProtKB=G3RY48 G3RY48 ZNF804B PTHR17614:SF12 ZINC FINGER-CONTAINING ZINC FINGER PROTEIN 804B cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000025014.2|UniProtKB=A0A2I2ZQV9 A0A2I2ZQV9 RPS23 PTHR11652:SF44 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009431.3|UniProtKB=G3SHW3 G3SHW3 MRPL50 PTHR31542:SF1 39A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML50 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000041719.1|UniProtKB=A0A2I2ZYD2 A0A2I2ZYD2 TYW5 PTHR12461:SF104 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 5 catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723;dioxygenase activity#GO:0051213;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008926.3|UniProtKB=G3R0N5 G3R0N5 LOC101127950 PTHR45893:SF5 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 3 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000012980.3|UniProtKB=G3RTW6 G3RTW6 PLEKHA3 PTHR22902:SF60 SESQUIPEDALIAN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 3 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000007877.3|UniProtKB=G3RYD7 G3RYD7 WWC1 PTHR14791:SF22 BOMB/KIRA PROTEINS PROTEIN KIBRA protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell migration#GO:0016477;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000001986.3|UniProtKB=G3QHX1 G3QHX1 PHC3 PTHR12247:SF88 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000015412.3|UniProtKB=G3RHB8 G3RHB8 POLG2 PTHR10745:SF8 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 DNA POLYMERASE SUBUNIT GAMMA-2 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;catalytic activity, acting on a tRNA#GO:0140101;enzyme activator activity#GO:0008047;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;molecular function regulator activity#GO:0098772;catalytic activity, acting on RNA#GO:0140098 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial DNA metabolic process#GO:0032042;DNA-templated DNA replication#GO:0006261;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000004782.3|UniProtKB=G3QQ27 G3QQ27 CDCA7L PTHR31169:SF4 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED 7-LIKE PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000027137.2|UniProtKB=G3SH03 G3SH03 MKNK2 PTHR24349:SF254 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-INTERACTING SERINE_THREONINE-PROTEIN KINASE 2 protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Interleukin signaling pathway#P00036>MNK1/2#P00972;PDGF signaling pathway#P00047>MNK1/2#P01149;p38 MAPK pathway#P05918>MNK2#P06017;Oxidative stress response#P00046>MNK1/2#P01137 GORGO|Ensembl=ENSGGOG00000002236.3|UniProtKB=G3QIJ0 G3QIJ0 GPR55 PTHR24232:SF56 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 55 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012187.3|UniProtKB=G3R926 G3R926 CRELD1 PTHR24038:SF14 STABILIN PROTEIN DISULFIDE ISOMERASE CRELD1 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000016655.3|UniProtKB=A0A2I2ZUC3 A0A2I2ZUC3 SGPL1 PTHR42735:SF6 FAMILY NOT NAMED SPHINGOSINE-1-PHOSPHATE LYASE 1 aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000529.3|UniProtKB=G3QE36 G3QE36 PTHR14963:SF5 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 28 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of biological quality#GO:0065008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;negative regulation of cytoskeleton organization#GO:0051494;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cell communication#GO:0010646;regulation of stress fiber assembly#GO:0051492;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament organization#GO:0110053 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000038181.1|UniProtKB=A0A2I2Z2Y1 A0A2I2Z2Y1 LOC101125570 PTHR34707:SF1 VIMENTIN-TYPE INTERMEDIATE FILAMENT-ASSOCIATED COILED-COIL PROTEIN VIMENTIN-TYPE INTERMEDIATE FILAMENT-ASSOCIATED COILED-COIL PROTEIN GORGO|Ensembl=ENSGGOG00000002795.3|UniProtKB=G3QJZ0 G3QJZ0 SERPINA10 PTHR11461:SF191 SERINE PROTEASE INHIBITOR, SERPIN PROTEIN Z-DEPENDENT PROTEASE INHIBITOR enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Blood coagulation#P00011>ZPI#P00425 GORGO|Ensembl=ENSGGOG00000042600.1|UniProtKB=A0A2I2Y1S4 A0A2I2Y1S4 PTHR14682:SF1 KATNB1-LIKE PROTEIN 1 KATNB1-LIKE PROTEIN 1 cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 GORGO|Ensembl=ENSGGOG00000013332.3|UniProtKB=A0A2I2YP70 A0A2I2YP70 SYNE3 PTHR47535:SF2 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G NESPRIN-3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;nuclear migration#GO:0007097;establishment of localization in cell#GO:0051649;establishment of organelle localization#GO:0051656;transport#GO:0006810;intracellular transport#GO:0046907;organelle localization#GO:0051640;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 nuclear membrane#GO:0031965;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane#GO:0016020;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013141.3|UniProtKB=G3RBG2 G3RBG2 ZNF875 PTHR24381:SF395 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 875 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000009892.3|UniProtKB=G3R346 G3R346 CTNS PTHR13131:SF14 CYSTINOSIN CYSTINOSIN transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;transport#GO:0006810;vacuolar transmembrane transport#GO:0034486;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 amino acid transporter#PC00046;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000001799.3|UniProtKB=G3QHE5 G3QHE5 IL17RB PTHR15583:SF11 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR B signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025536.2|UniProtKB=A0A2I2Z0P6 A0A2I2Z0P6 PTHR11710:SF13 40S RIBOSOMAL PROTEIN S19 40S RIBOSOMAL PROTEIN S19 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007688.3|UniProtKB=A0A2I2ZPV7 A0A2I2ZPV7 PACS2 PTHR13280:SF15 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 2 protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;catabolic process#GO:0009056;organelle assembly#GO:0070925;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045 GORGO|Ensembl=ENSGGOG00000038504.1|UniProtKB=A0A2I2ZXK1 A0A2I2ZXK1 PTHR11760:SF38 30S/40S RIBOSOMAL PROTEIN S3 SMALL RIBOSOMAL SUBUNIT PROTEIN US3 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 positive regulation of signaling#GO:0023056;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;positive regulation of programmed cell death#GO:0043068;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 membraneless organelle#GO:0043228;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000038086.1|UniProtKB=A0A2I2YLJ1 A0A2I2YLJ1 B3GNT5 PTHR11214:SF21 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE LACTOSYLCERAMIDE 1,3-N-ACETYL-BETA-D-GLUCOSAMINYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000036191.1|UniProtKB=G3QNU3 G3QNU3 PTHR11388:SF154 ORGANIC ANION TRANSPORTER SLCO1B3-SLCO1B7 READTHROUGH TRANSCRIPT PROTEIN-RELATED bile acid transmembrane transporter activity#GO:0015125;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007030.3|UniProtKB=G3QVU3 G3QVU3 DNAJA1 PTHR43888:SF8 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 1 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;ATPase activator activity#GO:0001671;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 localization#GO:0051179;protein metabolic process#GO:0019538;protein refolding#GO:0042026;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;protein localization to organelle#GO:0033365;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;protein localization to mitochondrion#GO:0070585;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;response to heat#GO:0009408;macromolecule localization#GO:0033036;cellular response to heat#GO:0034605;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000022233.2|UniProtKB=A0A2I2Y9P1 A0A2I2Y9P1 PTHR42796:SF8 FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED FUMARYLACETOACETASE-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000041141.1|UniProtKB=A0A2I2YIX0 A0A2I2YIX0 PTHR12430:SF4 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG localization#GO:0051179;nucleic acid transport#GO:0050657;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;nucleobase-containing compound transport#GO:0015931;mitochondrial transport#GO:0006839;RNA localization#GO:0006403;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;establishment of RNA localization#GO:0051236;protein localization to mitochondrion#GO:0070585;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 mitochondrial outer membrane translocase complex#GO:0005742;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006956.3|UniProtKB=G3RS60 G3RS60 LOC101128585 PTHR24028:SF227 CADHERIN-87A PROTOCADHERIN GAMMA-A12 cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000002484.3|UniProtKB=G3QJ63 G3QJ63 FAM20B PTHR12450:SF14 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 GLYCOSAMINOGLYCAN XYLOSYLKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000015433.4|UniProtKB=G3RHD9 G3RHD9 LOC101126456 PTHR24300:SF400 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C9 binding#GO:0005488;tetrapyrrole binding#GO:0046906;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular response to xenobiotic stimulus#GO:0071466;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;arachidonate metabolic process#GO:0019369;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;xenobiotic metabolic process#GO:0006805;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000037601.1|UniProtKB=A0A2I2ZC13 A0A2I2ZC13 PTHR13809:SF5 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-5-RELATED pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;GABA-B receptor II signaling#P05731>Ggamma#P05754;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974 GORGO|Ensembl=ENSGGOG00000013479.3|UniProtKB=G3RCC1 G3RCC1 FOXF2 PTHR46262:SF3 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN F2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000014814.3|UniProtKB=A0A2I2YM91 A0A2I2YM91 STOML1 PTHR10264:SF130 BAND 7 PROTEIN-RELATED STOMATIN-LIKE PROTEIN 1 transporter regulator activity#GO:0141108;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000005570.3|UniProtKB=G3QS32 G3QS32 SLC22A24 PTHR24064:SF591 SOLUTE CARRIER FAMILY 22 MEMBER STEROID TRANSMEMBRANE TRANSPORTER SLC22A24 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000010898.3|UniProtKB=G3R5N9 G3R5N9 ZNF275 PTHR24409:SF450 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012680.2|UniProtKB=G3RA98 G3RA98 GPX8 PTHR11592:SF7 GLUTATHIONE PEROXIDASE PROTEIN PEROXIDASE GPX8 peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005748.3|UniProtKB=A0A2I2ZUH9 A0A2I2ZUH9 ZNF571 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000039633.1|UniProtKB=A0A2I2ZJD7 A0A2I2ZJD7 FAM229A PTHR35355:SF1 PROTEIN FAM229A PROTEIN FAM229A GORGO|Ensembl=ENSGGOG00000006733.3|UniProtKB=G3QV26 G3QV26 FUCA1 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 glycosidase#PC00110;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000026582.2|UniProtKB=G3SDP0 G3SDP0 RPLP0 PTHR45699:SF1 60S ACIDIC RIBOSOMAL PROTEIN P0 LARGE RIBOSOMAL SUBUNIT PROTEIN UL10-RELATED structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;rRNA binding#GO:0019843 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000015989.3|UniProtKB=G3RIT1 G3RIT1 DNAL1 PTHR15454:SF33 NISCHARIN RELATED DYNEIN AXONEMAL LIGHT CHAIN 1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003110.3|UniProtKB=G3QKT3 G3QKT3 MMS19 PTHR12891:SF1 DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19 MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008837.3|UniProtKB=G3R0F8 G3R0F8 RPS6KA3 PTHR24351:SF58 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;TORC1 signaling#GO:0038202;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;TOR signaling#GO:0031929;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;CCKR signaling map#P06959>RSK1/2#P07153;Interleukin signaling pathway#P00036>p90RSK#P00964;Ras Pathway#P04393>p90RSK#P04541;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 GORGO|Ensembl=ENSGGOG00000039924.1|UniProtKB=A0A2I2ZCH3 A0A2I2ZCH3 PTHR23050:SF484 CALCIUM BINDING PROTEIN EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 11 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;cation binding#GO:0043169;molecular function regulator activity#GO:0098772 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000016425.3|UniProtKB=G3QN97 G3QN97 SACS PTHR15600:SF44 SACSIN SACSIN heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 GORGO|Ensembl=ENSGGOG00000026271.2|UniProtKB=G3S778 G3S778 FOXO6 PTHR45767:SF5 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000024966.2|UniProtKB=A0A2I2YN55 A0A2I2YN55 PTHR11931:SF31 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE (2,3-DIPHOSPHOGLYCERATE-DEPENDENT) catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;intramolecular phosphotransferase activity#GO:0016868;isomerase activity#GO:0016853;phosphoglycerate mutase activity#GO:0004619 ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 isomerase#PC00135;mutase#PC00160 GORGO|Ensembl=ENSGGOG00000001314.3|UniProtKB=G3QG47 G3QG47 DNAJC3 PTHR44140:SF3 LD25575P DNAJ HOMOLOG SUBFAMILY C MEMBER 3 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000004587.3|UniProtKB=G3QPK2 G3QPK2 PAX8 PTHR45636:SF6 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000023895.2|UniProtKB=G3SF79 G3SF79 LOC101153131 PTHR24379:SF131 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 712 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000012631.3|UniProtKB=G3RA68 G3RA68 SF3A1 PTHR15316:SF1 SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED SPLICING FACTOR 3A SUBUNIT 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000009229.3|UniProtKB=A0A2I2Z510 A0A2I2Z510 CRIPTO3 PTHR14949:SF43 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 PROTEIN CRIPTO3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor serine/threonine kinase binding#GO:0033612;binding#GO:0005488 tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regionalization#GO:0003002;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;specification of symmetry#GO:0009799;cellular developmental process#GO:0048869;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;determination of left/right symmetry#GO:0007368;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;determination of bilateral symmetry#GO:0009855;vasculogenesis#GO:0001570;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;cell surface receptor signaling pathway#GO:0007166;left/right pattern formation#GO:0060972;vasculature development#GO:0001944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;signaling#GO:0023052;cell differentiation#GO:0030154;circulatory system development#GO:0072359;response to stimulus#GO:0050896;activin receptor signaling pathway#GO:0032924;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000013483.3|UniProtKB=A0A2I2YFB3 A0A2I2YFB3 PTHR10792:SF34 60S RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN EL24 RNA binding#GO:0003723;structural molecule activity#GO:0005198;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016390.3|UniProtKB=G3RJT9 G3RJT9 GRPEL1 PTHR21237:SF25 GRPE PROTEIN GRPE PROTEIN HOMOLOG 1, MITOCHONDRIAL enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010446.3|UniProtKB=G3R4I9 G3R4I9 APBB1IP PTHR11243:SF14 GROWTH FACTOR RECEPTOR-BOUND PROTEIN AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;cell morphogenesis#GO:0000902;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001399.3|UniProtKB=G3QGD0 G3QGD0 AGAP2 PTHR45819:SF3 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 enzyme activator activity#GO:0008047;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;negative regulation of neuron apoptotic process#GO:0043524;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of neuron apoptotic process#GO:0043523;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane#GO:0016020 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000034988.2|UniProtKB=A0A2I2ZWK9 A0A2I2ZWK9 PNPLA7 PTHR14226:SF23 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 7 carboxylic ester hydrolase activity#GO:0052689;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 esterase#PC00097;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000007448.3|UniProtKB=G3QWX1 G3QWX1 ABCF3 PTHR19211:SF117 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;ATP binding#GO:0005524;small molecule binding#GO:0036094;binding#GO:0005488 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000026289.2|UniProtKB=G3RNE0 G3RNE0 RRH PTHR24240:SF77 OPSIN VISUAL PIGMENT-LIKE RECEPTOR PEROPSIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;signaling#GO:0023052;cellular response to radiation#GO:0071478;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;detection of stimulus#GO:0051606;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000026060.2|UniProtKB=G3RG26 G3RG26 BMP4 PTHR11848:SF165 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 4 receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;heart morphogenesis#GO:0003007;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000016320.3|UniProtKB=G3RJM5 G3RJM5 GNPTG PTHR12630:SF6 N-LINKED OLIGOSACCHARIDE PROCESSING N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNIT GAMMA cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000037638.1|UniProtKB=A0A2I2ZK69 A0A2I2ZK69 PTHR23232:SF125 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000024787.2|UniProtKB=G3S774 G3S774 PDCD6IP PTHR23030:SF39 PCD6 INTERACTING PROTEIN-RELATED PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytokinesis#GO:0000910;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;cytoskeleton-dependent cytokinesis#GO:0061640;protein transport#GO:0015031;cell cycle process#GO:0022402;establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cell division#GO:0051301;modification-dependent protein catabolic process#GO:0019941;protein localization to organelle#GO:0033365;mitotic cytokinesis#GO:0000281;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000010099.3|UniProtKB=G3R3N4 G3R3N4 SLC12A3 PTHR11827:SF9 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 3 chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;chloride transport#GO:0006821;establishment of localization#GO:0051234;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;sodium ion transport#GO:0006814;monoatomic anion transport#GO:0006820;metal ion transport#GO:0030001 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000036695.1|UniProtKB=A0A2I2YC71 A0A2I2YC71 GPR87 PTHR24233:SF8 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 87 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000010777.3|UniProtKB=G3R5D6 G3R5D6 STBD1 PTHR15048:SF1 STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1 STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1 glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;carbohydrate catabolic process#GO:0016052;localization#GO:0051179;lysosomal transport#GO:0007041;energy reserve metabolic process#GO:0006112;macroautophagy#GO:0016236;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;glycogen catabolic process#GO:0005980;energy derivation by oxidation of organic compounds#GO:0015980;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000013364.3|UniProtKB=G3RC19 G3RC19 TMCO6 PTHR16356:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 TMCO6 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 GORGO|Ensembl=ENSGGOG00000022792.2|UniProtKB=G3S7V8 G3S7V8 LOC101134272 PTHR46047:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 2 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;hydrolase activity#GO:0016787;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260;protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000015620.3|UniProtKB=G3S682 G3S682 SKP2 PTHR16134:SF32 F-BOX/TPR REPEAT PROTEIN POF3 S-PHASE KINASE-ASSOCIATED PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 positive regulation of DNA metabolic process#GO:0051054;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of double-strand break repair#GO:2000781;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein metabolic process#GO:0019538;regulation of double-strand break repair#GO:2000779;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of DNA recombination#GO:0000018;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011331.3|UniProtKB=G3R6T1 G3R6T1 CLIC1 PTHR45476:SF2 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;monoatomic anion transport#GO:0006820 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000025664.2|UniProtKB=G3RYZ0 G3RYZ0 ZNF639 PTHR24404:SF35 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 639 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000043184.1|UniProtKB=A0A2I2ZMQ6 A0A2I2ZMQ6 PTHR22745:SF0 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;positive regulation of transcription by RNA polymerase II#GO:0045944 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000003571.3|UniProtKB=G3QLY9 G3QLY9 LRRC9 PTHR46652:SF3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 GORGO|Ensembl=ENSGGOG00000010473.3|UniProtKB=A0A2I2ZIJ2 A0A2I2ZIJ2 PTGDR PTHR11866:SF14 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN D2 RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;regulation of biological quality#GO:0065008;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004750.3|UniProtKB=A0A2I2ZTS6 A0A2I2ZTS6 LIMS2 PTHR24210:SF10 LIM DOMAIN-CONTAINING PROTEIN LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 2 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell junction organization#GO:0034330;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;positive regulation of signaling#GO:0023056;cell adhesion#GO:0007155;regulation of signaling#GO:0023051 cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell-cell junction#GO:0005911;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 GORGO|Ensembl=ENSGGOG00000014491.3|UniProtKB=G3RF06 G3RF06 RNF17 PTHR16442:SF1 RING FINGER PROTEIN 17 RING FINGER PROTEIN 17 GORGO|Ensembl=ENSGGOG00000024280.2|UniProtKB=G3S7I2 G3S7I2 PTHR19433:SF72 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA CHAIN MC.7.G5-RELATED response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000022737.2|UniProtKB=G3S364 G3S364 ADM5 PTHR23414:SF6 ADRENOMEDULLIN, ADM ADRENOMEDULLIN-5-LIKE PROTEIN-RELATED hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;renal system process#GO:0003014;cellular process#GO:0009987;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of system process#GO:0044057;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;system process#GO:0003008;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of heart contraction#GO:0008016;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000026047.2|UniProtKB=A0A2I2YBC3 A0A2I2YBC3 MAX PTHR10328:SF3 PROTEIN MAX MYC-ASSOCIATED FACTOR X PROTEIN MAX transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 Oxidative stress response#P00046>Max#P01133 GORGO|Ensembl=ENSGGOG00000040803.1|UniProtKB=A0A2I2Y3M4 A0A2I2Y3M4 PTHR22904:SF516 TPR REPEAT CONTAINING PROTEIN STRESS INDUCED PHOSPHOPROTEIN 1 heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;binding#GO:0005488;protein binding#GO:0005515 GORGO|Ensembl=ENSGGOG00000001104.3|UniProtKB=G3QFL1 G3QFL1 PHF5A PTHR13120:SF0 PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000011778.3|UniProtKB=G3R7Y9 G3R7Y9 TRMT1L PTHR10631:SF1 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRNA (GUANINE(27)-N(2))-DIMETHYLTRANSFERASE catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000016207.3|UniProtKB=G3RJC9 G3RJC9 GABRR1 PTHR18945:SF30 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-1 transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;monoatomic anion channel activity#GO:0005253;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;cell communication#GO:0007154;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234 synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000015229.3|UniProtKB=A0A2I2Z7J6 A0A2I2Z7J6 CTNND1 PTHR10372:SF6 PLAKOPHILLIN-RELATED CATENIN DELTA-1 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944 intermediate filament binding protein#PC00130;intermediate filament#PC00129;cytoskeletal protein#PC00085 Cadherin signaling pathway#P00012>P120#P00473 GORGO|Ensembl=ENSGGOG00000001604.3|UniProtKB=G3QGW4 G3QGW4 LRRTM1 PTHR45617:SF94 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 1 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009053.3|UniProtKB=G3R105 G3R105 TRA2A PTHR48034:SF14 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG ALPHA binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012682.3|UniProtKB=G3RAA9 G3RAA9 RSKR PTHR24355:SF1 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE-RELATED PROTEIN protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000011519.3|UniProtKB=G3R7B7 G3R7B7 NUP205 PTHR31344:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP205 NUCLEAR PORE COMPLEX PROTEIN NUP205 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nuclear pore organization#GO:0006999 intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967 GORGO|Ensembl=ENSGGOG00000006346.3|UniProtKB=G3QU19 G3QU19 DOK1 PTHR21258:SF46 DOCKING PROTEIN RELATED DOCKING PROTEIN 1 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dok-R#P00180 GORGO|Ensembl=ENSGGOG00000016041.3|UniProtKB=G3RIX9 G3RIX9 VPS25 PTHR13149:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS25 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25 late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization to vacuole#GO:0072666;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein transport#GO:0015031;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;endosomal transport#GO:0016197;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;protein localization to vacuole#GO:0072665;localization#GO:0051179;protein metabolic process#GO:0019538;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;macromolecule localization#GO:0033036;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000006600.3|UniProtKB=G3QUQ5 G3QUQ5 PRKG2 PTHR24353:SF24 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567 GORGO|Ensembl=ENSGGOG00000041557.1|UniProtKB=A0A2I2Y9J0 A0A2I2Y9J0 PXMP2 PTHR11266:SF134 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 PEROXISOMAL MEMBRANE PROTEIN 2 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015509.3|UniProtKB=G3S678 G3S678 MLLT6 PTHR13793:SF90 PHD FINGER PROTEINS PROTEIN AF-17 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000016547.3|UniProtKB=G3RK85 G3RK85 CAMK1D PTHR24347:SF252 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;calmodulin binding#GO:0005516 signaling#GO:0023052;regulation of cellular component organization#GO:0051128;regulation of leukocyte migration#GO:0002685;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of chemotaxis#GO:0050920;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of granulocyte chemotaxis#GO:0071622;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of response to external stimulus#GO:0032101;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000040052.1|UniProtKB=A0A2I2ZCT3 A0A2I2ZCT3 PTHR46664:SF3 ATM INTERACTOR ATM INTERACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000014807.3|UniProtKB=A0A2I2Y557 A0A2I2Y557 ADCY7 PTHR45627:SF9 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 7 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824 response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cyclic purine nucleotide metabolic process#GO:0052652;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 5HT1 type receptor mediated signaling pathway#P04373>AC#P04406;Beta3 adrenergic receptor signaling pathway#P04379>AC#P04450;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Dopamine receptor mediated signaling pathway#P05912>AC#P05947;Opioid prodynorphin pathway#P05916>AC#P06001;Beta1 adrenergic receptor signaling pathway#P04377>AC#P04439;Opioid proenkephalin pathway#P05915>AC#P05993;Beta2 adrenergic receptor signaling pathway#P04378>AC#P04446;5HT4 type receptor mediated signaling pathway#P04376>AC#P04429;Histamine H2 receptor mediated signaling pathway#P04386>AC#P04492;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Enkephalin release#P05913>AC#P05978;Opioid proopiomelanocortin pathway#P05917>AC#P06011 GORGO|Ensembl=ENSGGOG00000004051.3|UniProtKB=G3R718 G3R718 MYL12B PTHR23049:SF58 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 12B protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;stress fiber#GO:0001725;membraneless organelle#GO:0043228;myosin complex#GO:0016459;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000015435.3|UniProtKB=G3RHE2 G3RHE2 LPL PTHR11610:SF3 LIPASE LIPOPROTEIN LIPASE protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;binding#GO:0005488;lipase activity#GO:0016298;catalytic activity#GO:0003824 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;lipid catabolic process#GO:0016042;cellular process#GO:0009987;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 2-arachidonoylglycerol biosynthesis#P05726>DGL#P05736 GORGO|Ensembl=ENSGGOG00000040311.1|UniProtKB=G3QKC9 G3QKC9 LOC101126098 PTHR23430:SF72 HISTONE H2A HISTONE H2A TYPE 2-B structural molecule activity#GO:0005198 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component assembly#GO:0022607;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000224.3|UniProtKB=G3QDB0 G3QDB0 DUSP8 PTHR10159:SF108 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 8 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000010923.3|UniProtKB=G3R5R3 G3R5R3 PAQR6 PTHR20855:SF39 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR DELTA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000014947.3|UniProtKB=G3RG46 G3RG46 G3BP2 PTHR10693:SF10 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 2 RNA binding#GO:0003723;molecular condensate scaffold activity#GO:0140693;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000000050.3|UniProtKB=G3QCV1 G3QCV1 GCHFR PTHR16852:SF2 GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000006060.3|UniProtKB=G3QTB7 G3QTB7 DGCR6L PTHR13054:SF2 DIGEORGE SYNDROME CRITICAL REGION 6 DGCR6 FAMILY MEMBER PROTEIN DGCR6 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000036253.1|UniProtKB=A0A2I2Y826 A0A2I2Y826 LOC101143262 PTHR48036:SF11 SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED RRM DOMAIN-CONTAINING PROTEIN binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000025089.2|UniProtKB=G3S156 G3S156 PRDX2 PTHR10681:SF161 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-2 antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;response to toxic substance#GO:0009636;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;response to stress#GO:0006950;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular homeostasis#GO:0019725;response to reactive oxygen species#GO:0000302;cell redox homeostasis#GO:0045454;cellular response to chemical stress#GO:0062197;superoxide metabolic process#GO:0006801;response to oxidative stress#GO:0006979 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176;peroxidase#PC00180 GORGO|Ensembl=ENSGGOG00000010226.3|UniProtKB=G3R3Z2 G3R3Z2 NR5A2 PTHR24086:SF18 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;hormone-mediated signaling pathway#GO:0009755;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to hormone#GO:0009725;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;tissue development#GO:0009888;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000027046.2|UniProtKB=G3SFZ0 G3SFZ0 BYSL PTHR12821:SF0 BYSTIN BYSTIN binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;RNA binding#GO:0003723 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000003903.3|UniProtKB=G3QMT8 G3QMT8 BBS4 PTHR44186:SF1 FAMILY NOT NAMED BBSOME COMPLEX MEMBER BBS4 GORGO|Ensembl=ENSGGOG00000036697.1|UniProtKB=A0A2I2Y4B6 A0A2I2Y4B6 LOC101135415 PTHR23226:SF75 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000034849.2|UniProtKB=A0A2I2YIG8 A0A2I2YIG8 TTC8 PTHR44177:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 8 TETRATRICOPEPTIDE REPEAT PROTEIN 8 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 microtubule cytoskeleton#GO:0015630;BBSome#GO:0034464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;intracellular organelle#GO:0043229;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007545.3|UniProtKB=G3SCA5 G3SCA5 CDC7 PTHR11909:SF7 CASEIN KINASE-RELATED CELL DIVISION CYCLE 7-RELATED PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;cell communication#GO:0007154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000017165.3|UniProtKB=A0A2I2Z779 A0A2I2Z779 PTHR42690:SF3 THREONINE SYNTHASE FAMILY MEMBER THREONINE SYNTHASE-LIKE 2 catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;lyase activity#GO:0016829 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 Threonine biosynthesis#P02781>Threonine synthase#P03190 GORGO|Ensembl=ENSGGOG00000000944.3|UniProtKB=G3QF65 G3QF65 ADAD2 PTHR10910:SF106 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;tRNA-specific adenosine deaminase activity#GO:0008251;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;base conversion or substitution editing#GO:0016553;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;adenosine to inosine editing#GO:0006382;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000028193.2|UniProtKB=G3RYG7 G3RYG7 LOC101151629 PTHR12884:SF36 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014213.3|UniProtKB=G3RE89 G3RE89 GPR137C PTHR15146:SF1 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137C positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of TORC1 signaling#GO:1904263;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000041046.1|UniProtKB=A0A2I2ZVX1 A0A2I2ZVX1 LOC101134688 PTHR23239:SF355 INTERMEDIATE FILAMENT IF ROD DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198 developmental process#GO:0032502;epidermis development#GO:0008544;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000002614.3|UniProtKB=G3QJH8 G3QJH8 DECR1 PTHR43658:SF14 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING], MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000007076.3|UniProtKB=G3QVY6 G3QVY6 PRIM2 PTHR10537:SF3 DNA PRIMASE LARGE SUBUNIT DNA PRIMASE LARGE SUBUNIT metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;RNA biosynthetic process#GO:0032774 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nuclear DNA-directed RNA polymerase complex#GO:0055029;replisome#GO:0030894;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622 primase#PC00189 DNA replication#P00017>Primase#P00528 GORGO|Ensembl=ENSGGOG00000009224.3|UniProtKB=G3RYI6 G3RYI6 SLC4A4 PTHR11453:SF10 ANION EXCHANGE PROTEIN ELECTROGENIC SODIUM BICARBONATE COTRANSPORTER 1 monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106 regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000013900.3|UniProtKB=G3RDF3 G3RDF3 GABPA PTHR11849:SF195 ETS GA-BINDING PROTEIN ALPHA CHAIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000013133.3|UniProtKB=G3RBF3 G3RBF3 CIMAP1A PTHR21580:SF23 SHIPPO-1-RELATED CILIARY MICROTUBULE ASSOCIATED PROTEIN 1A flagellated sperm motility#GO:0030317;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;sperm motility#GO:0097722;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000017103.3|UniProtKB=G3RLN8 G3RLN8 LOC101134686 PTHR11801:SF47 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5A cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;response to endogenous stimulus#GO:0009719;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;interleukin-7-mediated signaling pathway#GO:0038111;response to chemokine#GO:1990868;response to hormone#GO:0009725;response to stress#GO:0006950;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;interleukin-15-mediated signaling pathway#GO:0035723;interleukin-9-mediated signaling pathway#GO:0038113;cell surface receptor signaling pathway via STAT#GO:0097696;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;chemokine-mediated signaling pathway#GO:0070098;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;interleukin-2-mediated signaling pathway#GO:0038110;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to chemokine#GO:1990869;cellular response to peptide hormone stimulus#GO:0071375;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to peptide hormone#GO:0043434 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;JAK/STAT signaling pathway#P00038>STAT#P01027 GORGO|Ensembl=ENSGGOG00000000319.3|UniProtKB=G3QDJ1 G3QDJ1 ZBTB16 PTHR24409:SF363 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN CONTAINING 32 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022704.2|UniProtKB=G3RS38 G3RS38 PTHR45809:SF4 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 3 protein binding#GO:0005515;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;growth factor receptor binding#GO:0070851 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;tube development#GO:0035295;biosynthetic process#GO:0009058;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;primary metabolic process#GO:0044238;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;protein maturation#GO:0051604;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;circulatory system development#GO:0072359;protein folding#GO:0006457;animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000003221.3|UniProtKB=A0A2I2Y713 A0A2I2Y713 ASB17 PTHR20966:SF2 ANKYRIN REPEAT AND SOCS BOX PROTEIN 17 ANKYRIN REPEAT AND SOCS BOX PROTEIN 17 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of apoptotic process#GO:0042981;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000023574.2|UniProtKB=G3RSY3 G3RSY3 CRNN PTHR11639:SF26 S100 CALCIUM-BINDING PROTEIN CORNULIN cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 cell motility#GO:0048870;endothelial cell migration#GO:0043542;cell migration#GO:0016477;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000023590.2|UniProtKB=A0A2I2YIU9 A0A2I2YIU9 PTHR45729:SF7 RABPHILIN, ISOFORM A DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN GAMMA synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;regulation of exocytosis#GO:0017157;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;regulation of localization#GO:0032879;exocytosis#GO:0006887;regulation of transport#GO:0051049;positive regulation of vesicle fusion#GO:0031340;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;positive regulation of secretion#GO:0051047;positive regulation of cellular component organization#GO:0051130;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;export from cell#GO:0140352;signaling#GO:0023052 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003971.3|UniProtKB=G3QN02 G3QN02 KIF23 PTHR24115:SF600 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF23 hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887 cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;spindle assembly#GO:0051225;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;microtubule-based movement#GO:0007018;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;nuclear division#GO:0000280 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000012911.3|UniProtKB=G3RAW1 G3RAW1 CNGA2 PTHR45638:SF3 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-2 monoatomic cation transmembrane transporter activity#GO:0008324;guanyl ribonucleotide binding#GO:0032561;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;monoatomic ion channel activity#GO:0005216;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;monoatomic ion transmembrane transporter activity#GO:0015075;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 cellular process#GO:0009987;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;sensory perception of chemical stimulus#GO:0007606;transport#GO:0006810;nervous system process#GO:0050877;sensory perception#GO:0007600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;system process#GO:0003008 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 ion channel#PC00133;ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000001334.3|UniProtKB=G3QG66 G3QG66 TRMT112 PTHR12773:SF0 UPF0315 PROTEIN-RELATED MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;methyltransferase complex#GO:0034708 GORGO|Ensembl=ENSGGOG00000012268.3|UniProtKB=A0A2I2Y2M5 A0A2I2Y2M5 XAF1 PTHR16295:SF17 TRAF-TYPE ZINC FINGER PROTEIN-RELATED XIAP-ASSOCIATED FACTOR 1 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000000227.3|UniProtKB=A0A2I2Z831 A0A2I2Z831 POU6F1 PTHR11636:SF6 POU DOMAIN POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000025148.2|UniProtKB=A0A2I2Y982 A0A2I2Y982 PTHR23073:SF79 26S PROTEASOME REGULATORY SUBUNIT AAA+ ATPASE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;isomerase activity#GO:0016853 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502 protease#PC00190 GORGO|Ensembl=ENSGGOG00000014204.3|UniProtKB=G3RE82 G3RE82 KIF12 PTHR24115:SF418 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF12 cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000040782.1|UniProtKB=A0A2I2Z5L7 A0A2I2Z5L7 PTHR12373:SF8 ENHANCER OF RUDIMENTARY ERH ENHANCER OF RUDIMENTARY HOMOLOG molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;nuclear mRNA surveillance#GO:0071028;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;regulation of chromatin organization#GO:1902275 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016952.3|UniProtKB=G3RLA3 G3RLA3 TMEM14C PTHR12668:SF4 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14C-RELATED tetrapyrrole biosynthetic process#GO:0033014;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987;porphyrin-containing compound biosynthetic process#GO:0006779;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015170.3|UniProtKB=G3S2M1 G3S2M1 PIM1 PTHR22984:SF29 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE PIM-1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;regulation of TOR signaling#GO:0032006;regulation of mitotic cell cycle#GO:0007346;positive regulation of TORC1 signaling#GO:1904263;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001153.3|UniProtKB=G3QFQ8 G3QFQ8 PTHR15468:SF7 ZNF185 SCIELLIN developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;epidermis development#GO:0008544;tissue development#GO:0009888;anatomical structure development#GO:0048856 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009535.3|UniProtKB=A0A2I2ZFZ6 A0A2I2ZFZ6 NDRG4 PTHR11034:SF21 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG4 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000034903.2|UniProtKB=G3SKW1 G3SKW1 DCDC2 PTHR23004:SF5 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2 cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of cilium assembly#GO:1902017;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of plasma membrane bounded cell projection assembly#GO:0120032;cell differentiation#GO:0030154;regulation of cellular component biogenesis#GO:0044087;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cilium organization#GO:0044782;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;cell migration#GO:0016477;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of organelle assembly#GO:1902115;regulation of plasma membrane bounded cell projection organization#GO:0120035;neuron migration#GO:0001764;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;plasma membrane bounded cell projection assembly#GO:0120031;regulation of cell projection organization#GO:0031344;developmental process#GO:0032502;cell motility#GO:0048870;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cell projection assembly#GO:0060491;organelle assembly#GO:0070925 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000025169.2|UniProtKB=G3RWC6 G3RWC6 DUSP16 PTHR10159:SF343 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 16 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000011618.3|UniProtKB=G3R7J9 G3R7J9 GRK5 PTHR24355:SF27 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 5 protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK5#P05940;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 GORGO|Ensembl=ENSGGOG00000015173.3|UniProtKB=G3RGQ2 G3RGQ2 PLEKHM2 PTHR46556:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 endomembrane system organization#GO:0010256;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;regulation of biological process#GO:0050789;cellular process#GO:0009987;lysosome localization#GO:0032418;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;organelle localization#GO:0051640 endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000038666.1|UniProtKB=A0A2I2Y1Y4 A0A2I2Y1Y4 PTHR23266:SF330 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-5 binding#GO:0005488;antigen binding#GO:0003823 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000021928.2|UniProtKB=G3S939 G3S939 LOC101141938 PTHR47966:SF13 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CHYMOSIN aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 aspartic protease#PC00053;protease#PC00190 GORGO|Ensembl=ENSGGOG00000003220.3|UniProtKB=G3QL27 G3QL27 NOX4 PTHR11972:SF206 NADPH OXIDASE NADPH OXIDASE 4 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664 superoxide metabolic process#GO:0006801;response to stimulus#GO:0050896;defense response#GO:0006952;reactive oxygen species metabolic process#GO:0072593;response to stress#GO:0006950;metabolic process#GO:0008152;cellular process#GO:0009987 catalytic complex#GO:1902494;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidase#PC00175;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006267.3|UniProtKB=A0A2I2ZNQ2 A0A2I2ZNQ2 C6H7orf57 PTHR31097:SF2 SI:DKEY-276J7.1 CHROMOSOME 7 OPEN READING FRAME 57 GORGO|Ensembl=ENSGGOG00000008940.3|UniProtKB=G3RW35 G3RW35 LOC101146296 PTHR37553:SF6 DUF4705 DOMAIN-CONTAINING PROTEIN DUF4705 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000042794.1|UniProtKB=G3R2E6 G3R2E6 LOC101141508 PTHR20648:SF15 ELONGIN-C ELONGIN-C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000003514.3|UniProtKB=G3RVB3 G3RVB3 ZNF414 PTHR21695:SF0 ZINC FINGER PROTEIN 414 ZINC FINGER PROTEIN 414 GORGO|Ensembl=ENSGGOG00000000615.3|UniProtKB=G3RYU9 G3RYU9 RAB19 PTHR24073:SF362 DRAB5-RELATED RAS-RELATED PROTEIN RAB-19 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000000571.3|UniProtKB=G3QE73 G3QE73 FAR2 PTHR11011:SF120 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE 2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000023646.2|UniProtKB=G3SCZ5 G3SCZ5 FLRT1 PTHR45712:SF15 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000038436.1|UniProtKB=A0A2I2YFM3 A0A2I2YFM3 PTHR19367:SF24 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-4 immune response#GO:0006955;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000040626.1|UniProtKB=A0A2I2Z8Y1 A0A2I2Z8Y1 PTHR10177:SF62 CYCLINS CYCLIN-J cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000006307.3|UniProtKB=G3QTY4 G3QTY4 PTHR18934:SF108 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE HOMOLOG DQX1 ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;helicase activity#GO:0004386 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000043097.1|UniProtKB=A0A2I2YW81 A0A2I2YW81 PTHR31882:SF8 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER CCHC NOA-TYPE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;immune response-regulating signaling pathway#GO:0002764;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;cellular response to lipid#GO:0071396;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular response to oxygen-containing compound#GO:1901701;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;response to lipopolysaccharide#GO:0032496;immune response-activating signaling pathway#GO:0002757;regulation of cell communication#GO:0010646;intracellular receptor signaling pathway#GO:0030522;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;positive regulation of signal transduction#GO:0009967;innate immune response-activating signaling pathway#GO:0002758;regulation of RNA metabolic process#GO:0051252;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of signaling#GO:0023056;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular response to lipopolysaccharide#GO:0071222;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of response to external stimulus#GO:0032103;cell surface receptor signaling pathway#GO:0007166;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;positive regulation of cell communication#GO:0010647;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;response to bacterium#GO:0009617;response to other organism#GO:0051707;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;positive regulation of innate immune response#GO:0045089;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stress#GO:0080134 GORGO|Ensembl=ENSGGOG00000016616.3|UniProtKB=G3S9J3 G3S9J3 ADGRB2 PTHR12011:SF41 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR B2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;developmental process#GO:0032502;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;peripheral nervous system development#GO:0007422;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 p53 pathway#P00059>BAI-1#G04699 GORGO|Ensembl=ENSGGOG00000016047.3|UniProtKB=G3SCQ7 G3SCQ7 NKX6-3 PTHR24340:SF120 HOMEOBOX PROTEIN NKX NK6 HOMEOBOX 3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000016945.3|UniProtKB=G3SDK4 G3SDK4 ATRN PTHR46376:SF3 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 ATTRACTIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000006151.3|UniProtKB=A0A2I2Z9V9 A0A2I2Z9V9 SLIT2 PTHR45836:SF2 SLIT HOMOLOG SLIT HOMOLOG 2 PROTEIN protein binding#GO:0005515;heparin binding#GO:0008201;binding#GO:0005488;signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367 chemotaxis#GO:0006935;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of growth#GO:0040008;locomotion#GO:0040011;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;negative regulation of cellular process#GO:0048523;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cell growth#GO:0030308;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;response to chemical#GO:0042221;taxis#GO:0042330;regulation of cell growth#GO:0001558 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 GORGO|Ensembl=ENSGGOG00000007343.4|UniProtKB=G3QWN3 G3QWN3 DCC PTHR10075:SF115 BASIGIN RELATED NETRIN RECEPTOR DCC cell adhesion molecule#PC00069 Axon guidance mediated by Slit/Robo#P00008>DCC#P00352;Axon guidance mediated by netrin#P00009>DCC/UNC-40#P00360 GORGO|Ensembl=ENSGGOG00000010693.3|UniProtKB=G3R555 G3R555 LRRC42 PTHR31994:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42 GORGO|Ensembl=ENSGGOG00000014371.3|UniProtKB=G3REN0 G3REN0 METTL23 PTHR14614:SF167 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTONE-ARGININE METHYLTRANSFERASE METTL23 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993 cellular component organization#GO:0016043;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008992.3|UniProtKB=G3R0U7 G3R0U7 TBC1D20 PTHR20913:SF10 TBC1 DOMAIN FAMILY MEMBER 20/GTPASE TBC1 DOMAIN FAMILY MEMBER 20 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular localization#GO:0051641;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000010644.3|UniProtKB=G3R525 G3R525 NPHP3 PTHR19871:SF36 BETA TRANSDUCIN-RELATED PROTEIN NEPHROCYSTIN-3 GORGO|Ensembl=ENSGGOG00000009681.3|UniProtKB=G3R2K0 G3R2K0 HS3ST4 PTHR10605:SF11 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001967.3|UniProtKB=G3QHV3 G3QHV3 EVI5L PTHR22957:SF254 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN EVI5-LIKE PROTEIN enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000008560.3|UniProtKB=G3RVK5 G3RVK5 JMY PTHR23330:SF8 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED JUNCTION-MEDIATING AND -REGULATORY PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;protein-containing complex binding#GO:0044877;transcription coactivator activity#GO:0003713 actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;actin nucleation#GO:0045010;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029;biological regulation#GO:0065007;Arp2/3 complex-mediated actin nucleation#GO:0034314;positive regulation of cellular process#GO:0048522;actin filament organization#GO:0007015;apoptotic signaling pathway#GO:0097190;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;intrinsic apoptotic signaling pathway#GO:0097193;signal transduction by p53 class mediator#GO:0072331;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000042352.1|UniProtKB=A0A2I2YWU7 A0A2I2YWU7 PTHR48033:SF9 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN TAR DNA-BINDING PROTEIN 43 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010036.3|UniProtKB=G3SEF1 G3SEF1 DAW1 PTHR44156:SF33 SUPERNUMERARY LIMBS, ISOFORM B-RELATED DYNEIN ASSEMBLY FACTOR WITH WD REPEAT DOMAINS 1 cytoskeleton organization#GO:0007010;determination of bilateral symmetry#GO:0009855;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;regionalization#GO:0003002;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;left/right pattern formation#GO:0060972;developmental process#GO:0032502;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;determination of left/right symmetry#GO:0007368;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cilium organization#GO:0044782;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;pattern specification process#GO:0007389;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925 GORGO|Ensembl=ENSGGOG00000012828.3|UniProtKB=G3RAQ4 G3RAQ4 IGF1R PTHR24416:SF106 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 positive regulation of cellular process#GO:0048522;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to glucose#GO:0009749;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;positive regulation of MAPK cascade#GO:0043410;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;homeostatic process#GO:0042592;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;response to chemical#GO:0042221;chemical homeostasis#GO:0048878;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;cellular response to glucose stimulus#GO:0071333;glucose homeostasis#GO:0042593;regulation of JNK cascade#GO:0046328;carbohydrate homeostasis#GO:0033500;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;response to hexose#GO:0009746;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;insulin-like growth factor receptor signaling pathway#GO:0048009;regulation of signaling#GO:0023051;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;response to monosaccharide#GO:0034284;cellular response to chemical stimulus#GO:0070887;intracellular glucose homeostasis#GO:0001678;response to carbohydrate#GO:0009743;positive regulation of signaling#GO:0023056 axon#GO:0030424;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;transferase complex#GO:1990234;protein kinase complex#GO:1902911;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Gonadotropin-releasing hormone receptor pathway#P06664>IGF-1R#P06703;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 GORGO|Ensembl=ENSGGOG00000012661.4|UniProtKB=A0A2I2YRZ6 A0A2I2YRZ6 SLC8A1 PTHR11878:SF6 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 1 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;regulation of system process#GO:0044057;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;regulation of heart contraction#GO:0008016;homeostatic process#GO:0042592;metal ion transport#GO:0030001;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;chemical homeostasis#GO:0048878;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;export from cell#GO:0140352;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085 neuron projection#GO:0043005;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;axon#GO:0030424;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;sarcolemma#GO:0042383;cell junction#GO:0030054 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000007986.3|UniProtKB=G3SIM5 G3SIM5 LOC101147767 PTHR48018:SF144 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9Q2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025007.2|UniProtKB=G3RWK1 G3RWK1 FAM13B PTHR15904:SF16 FAM13 PROTEIN FAM13B GORGO|Ensembl=ENSGGOG00000014247.3|UniProtKB=A0A2I2YPU5 A0A2I2YPU5 PYCR2 PTHR11645:SF61 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 reductase#PC00198;metabolite interconversion enzyme#PC00262 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 GORGO|Ensembl=ENSGGOG00000005007.3|UniProtKB=G3QQN5 G3QQN5 SH3BGR PTHR12232:SF1 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 GORGO|Ensembl=ENSGGOG00000001973.3|UniProtKB=A0A2I2ZHP3 A0A2I2ZHP3 PTHR24343:SF84 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE BRSK2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular component organization#GO:0016043;cell cycle process#GO:0022402;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;cell cycle#GO:0007049;establishment of cell polarity#GO:0030010;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;mitotic cell cycle phase transition#GO:0044772;anatomical structure development#GO:0048856;system development#GO:0048731;axon development#GO:0061564;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;mitotic cell cycle process#GO:1903047 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000016672.3|UniProtKB=G3RKJ9 G3RKJ9 CHMP4C PTHR22761:SF77 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4C organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;vesicle budding from membrane#GO:0006900;cellular component organization#GO:0016043;membrane assembly#GO:0071709;late endosome to vacuole transport#GO:0045324;localization#GO:0051179;cellular localization#GO:0051641 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cytoplasmic side of plasma membrane#GO:0009898;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic side of membrane#GO:0098562 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000042266.1|UniProtKB=A0A2I2Z998 A0A2I2Z998 PTHR23115:SF310 TRANSLATION FACTOR TR-TYPE G DOMAIN-CONTAINING PROTEIN GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152 translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000026468.2|UniProtKB=G3RZX4 G3RZX4 FHIP2A PTHR21705:SF10 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK INTERACTING PROTEIN 2A GORGO|Ensembl=ENSGGOG00000017132.3|UniProtKB=G3SIE4 G3SIE4 PLCG2 PTHR10336:SF25 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 phosphatidylinositol metabolic process#GO:0046488;transport#GO:0006810;lipid metabolic process#GO:0006629;regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;establishment of localization#GO:0051234;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;organophosphate metabolic process#GO:0019637;monoatomic ion transmembrane transport#GO:0034220;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;positive regulation of cell motility#GO:2000147;calcium ion transmembrane transport#GO:0070588;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896 cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;cell projection membrane#GO:0031253;ruffle#GO:0001726 hydrolase#PC00121;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143 VEGF signaling pathway#P00056>PLC-gamma#P01414;FGF signaling pathway#P00021>PLCgamma#P00638;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;B cell activation#P00010>PLC gamma2#P00388;Angiogenesis#P00005>PLC-gamma#P00256;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362;EGF receptor signaling pathway#P00018>PLCgamma#P00556;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;PDGF signaling pathway#P00047>PLCgamma#P01171;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412 GORGO|Ensembl=ENSGGOG00000000262.3|UniProtKB=G3QDE4 G3QDE4 SLC1A1 PTHR11958:SF109 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 3 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;sodium:dicarboxylate symporter activity#GO:0017153;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370 localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;L-glutamate import#GO:0051938;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;transport#GO:0006810;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 GORGO|Ensembl=ENSGGOG00000004529.3|UniProtKB=G3SE66 G3SE66 POLM PTHR11276:SF24 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA-DIRECTED DNA_RNA POLYMERASE MU DNA-directed DNA polymerase activity#GO:0003887;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000027385.2|UniProtKB=G3SAD6 G3SAD6 SI PTHR22762:SF66 ALPHA-GLUCOSIDASE SUCRASE-ISOMALTASE, INTESTINAL alpha-glucosidase activity#GO:0090599;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glucosidase#PC00108 GORGO|Ensembl=ENSGGOG00000042200.1|UniProtKB=A0A2I2Y2Y6 A0A2I2Y2Y6 PTHR11547:SF65 ARGININE OR CREATINE KINASE CREATINE KINASE U-TYPE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010958.3|UniProtKB=G3R5U8 G3R5U8 TAP1 PTHR24221:SF249 ATP-BINDING CASSETTE SUB-FAMILY B ANTIGEN PEPTIDE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;protein binding#GO:0005515 immune system process#GO:0002376;cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;antigen processing and presentation#GO:0019882;transmembrane transport#GO:0055085;localization#GO:0051179 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000009013.3|UniProtKB=G3R0X8 G3R0X8 RRBP1 PTHR18939:SF4 RIBOSOME BINDING PROTEIN-1 RIBOSOME-BINDING PROTEIN 1 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000025662.2|UniProtKB=G3SG89 G3SG89 PTHR11848:SF151 TGF-BETA FAMILY EMBRYONIC GROWTH_DIFFERENTIATION FACTOR 1 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000011159.3|UniProtKB=A0A2I2Y3D8 A0A2I2Y3D8 FBXL7 PTHR13318:SF50 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 7 GORGO|Ensembl=ENSGGOG00000015044.3|UniProtKB=G3RGE4 G3RGE4 PADI1 PTHR10837:SF11 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE TYPE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000011785.3|UniProtKB=G3R801 G3R801 NIBAN3 PTHR14392:SF4 NIBAN FAMILY MEMBER PROTEIN NIBAN 3 GORGO|Ensembl=ENSGGOG00000012108.3|UniProtKB=G3R8U6 G3R8U6 LOC101153001 PTHR24304:SF2 CYTOCHROME P450 FAMILY 7 24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000016031.3|UniProtKB=G3RIX6 G3RIX6 RNF31 PTHR16004:SF5 RING FINGER PROTEIN 31-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF31 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin binding#GO:0043130;transferase activity#GO:0016740;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;polyubiquitin modification-dependent protein binding#GO:0031593;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;modification-dependent protein binding#GO:0140030;acyltransferase activity#GO:0016746 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015282.3|UniProtKB=G3RH05 G3RH05 ARHGEF1 PTHR45872:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 protein binding#GO:0005515;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;G protein-coupled receptor binding#GO:0001664 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 Axon guidance mediated by semaphorins#P00007>RhoGEF#P00333;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoGEF#P00728;Cytoskeletal regulation by Rho GTPase#P00016>Rho GEFs#P00518 GORGO|Ensembl=ENSGGOG00000023700.2|UniProtKB=G3SA90 G3SA90 PTHR11595:SF21 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-DELTA enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000005878.3|UniProtKB=G3QSW3 G3QSW3 TELO2 PTHR15830:SF10 TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG heat shock protein binding#GO:0031072;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;Hsp90 protein binding#GO:0051879;nucleic acid binding#GO:0003676;binding#GO:0005488;protein binding#GO:0005515;DNA binding#GO:0003677 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000041266.1|UniProtKB=G3SG41 G3SG41 LOC101128475 PTHR24377:SF912 IP01015P-RELATED ZINC FINGER PROTEIN 254-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000039459.1|UniProtKB=G3QRQ1 G3QRQ1 PPAN PTHR12661:SF5 PETER PAN-RELATED SUPPRESSOR OF SWI4 1 HOMOLOG RNA binding#GO:0003723;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004166.3|UniProtKB=A0A2I2Z1D4 A0A2I2Z1D4 RFFL PTHR14879:SF2 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RIFIFYLIN transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of extrinsic apoptotic signaling pathway#GO:2001236;protein metabolic process#GO:0019538;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;regulation of apoptotic process#GO:0042981;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;negative regulation of signaling#GO:0023057 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000009519.3|UniProtKB=G3QLA6 G3QLA6 FSIP2 PTHR47315:SF3 FIBROUS SHEATH INTERACTING PROTEIN 2 FIBROUS SHEATH-INTERACTING PROTEIN 2-LIKE GORGO|Ensembl=ENSGGOG00000007958.3|UniProtKB=G3SBS4 G3SBS4 SIX5 PTHR10390:SF40 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX5 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000011460.3|UniProtKB=G3R748 G3R748 FMR1NB PTHR37360:SF1 FRAGILE X MENTAL RETARDATION 1 NEIGHBOR PROTEIN FMR1 NEIGHBOR PROTEIN GORGO|Ensembl=ENSGGOG00000014039.3|UniProtKB=G3RDT9 G3RDT9 DGKA PTHR11255:SF38 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000022243.2|UniProtKB=G3SIA3 G3SIA3 ARFGEF1 PTHR10663:SF137 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 1 organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000005445.3|UniProtKB=G3QRR6 G3QRR6 ADRB2 PTHR24248:SF21 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-2 ADRENERGIC RECEPTOR G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;system process#GO:0003008;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;regulation of biological quality#GO:0065008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;vasodilation#GO:0042311;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Beta2 adrenergic receptor signaling pathway#P04378>Beta2#P04440 GORGO|Ensembl=ENSGGOG00000011170.3|UniProtKB=G3R6D9 G3R6D9 PTHR44656:SF7 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 12 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 12 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000008319.3|UniProtKB=G3QZ27 G3QZ27 LOC101143583 PTHR23262:SF210 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-3 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000011997.3|UniProtKB=G3R8I6 G3R8I6 NPVF PTHR14403:SF6 RFAMIDE PEPTIDE GONADOTROPIN INHIBITORY HORMONE PRO-FMRFAMIDE-RELATED NEUROPEPTIDE VF protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;regulation of secretion by cell#GO:1903530;cell communication#GO:0007154;regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;regulation of transport#GO:0051049;regulation of localization#GO:0032879 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>RFRP-1/-3#P06828 GORGO|Ensembl=ENSGGOG00000016807.3|UniProtKB=G3RKX3 G3RKX3 STRIP2 PTHR13239:SF6 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 STRIATIN-INTERACTING PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cytoskeleton organization#GO:0007010;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;organelle organization#GO:0006996;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001008.4|UniProtKB=G3QFC6 G3QFC6 IQSEC1 PTHR10663:SF327 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 1 regulation of biological quality#GO:0065008;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of endocytosis#GO:0030100;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000014971.3|UniProtKB=G3RG68 G3RG68 G6PC2 PTHR12591:SF1 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE 2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glucose metabolic process#GO:0006006;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;small molecule metabolic process#GO:0044281 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000036463.1|UniProtKB=G3SK86 G3SK86 PTHR11639:SF67 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A7-LIKE 2 metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870;endothelial cell migration#GO:0043542 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000008608.3|UniProtKB=G3QZU8 G3QZU8 NPAS4 PTHR23043:SF24 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000028608.2|UniProtKB=G3S4C5 G3S4C5 ANK2 PTHR24133:SF36 ANKYRIN DOMAIN-CONTAINING ANKYRIN-2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004514.3|UniProtKB=G3QPD5 G3QPD5 LOC101151457 PTHR11876:SF19 ALPHA-DEFENSIN 1 NEUTROPHIL DEFENSIN 1-RELATED response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;defense response to Gram-positive bacterium#GO:0050830;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;response to external stimulus#GO:0009605;defense response#GO:0006952;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051 GORGO|Gene=1A02_GORGO|UniProtKB=P30376 P30376 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN signaling receptor binding#GO:0005102;binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823;protein binding#GO:0005515 regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of immune system process#GO:0002684 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000001091.3|UniProtKB=G3QFK1 G3QFK1 KNDC1 PTHR21560:SF0 VERY KIND PROTEIN KINASE NON-CATALYTIC C-LOBE DOMAIN-CONTAINING PROTEIN 1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of dendrite morphogenesis#GO:0048814;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344 intracellular protein-containing complex#GO:0140535;dendritic tree#GO:0097447;dendrite#GO:0030425;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell body#GO:0044297;neuron projection#GO:0043005 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000041210.1|UniProtKB=A0A2I2YMA4 A0A2I2YMA4 PTHR46754:SF1 MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000001506.3|UniProtKB=G3QGM7 G3QGM7 CCDC15 PTHR14817:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000014148.3|UniProtKB=A0A2I2Y4J9 A0A2I2Y4J9 CALCA PTHR10505:SF17 CALCITONIN-RELATED CALCITONIN RELATED POLYPEPTIDE ALPHA G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;homeostatic process#GO:0042592;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of cytosolic calcium ion concentration#GO:0051480;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;cell communication#GO:0007154;inorganic ion homeostasis#GO:0098771;G protein-coupled receptor signaling pathway#GO:0007186;calcium ion homeostasis#GO:0055074 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000007078.3|UniProtKB=G3QVY1 G3QVY1 F2RL1 PTHR24232:SF21 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of MAPK cascade#GO:0043410;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of signaling#GO:0023056;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016350.3|UniProtKB=G3RJQ2 G3RJQ2 TEX12 PTHR37349:SF1 TESTIS-EXPRESSED PROTEIN 12 TESTIS-EXPRESSED PROTEIN 12 cell cycle process#GO:0022402;cell cycle#GO:0007049;meiosis I#GO:0007127;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;reproductive process#GO:0022414;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;organelle fission#GO:0048285;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;homologous chromosome pairing at meiosis#GO:0007129;synaptonemal complex assembly#GO:0007130;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;meiotic nuclear division#GO:0140013 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;central element#GO:0000801;intracellular organelle lumen#GO:0070013;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;condensed chromosome#GO:0000793 GORGO|Ensembl=ENSGGOG00000015250.3|UniProtKB=G3RGW9 G3RGW9 LBR PTHR21257:SF55 DELTA(14)-STEROL REDUCTASE DELTA(14)-STEROL REDUCTASE LBR oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle inner membrane#GO:0019866;membrane#GO:0016020;nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle envelope#GO:0031967;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000008248.2|UniProtKB=G3QYW7 G3QYW7 PTHR22467:SF5 EZH INHIBITORY PROTEIN-RELATED EZH INHIBITORY PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000001772.3|UniProtKB=G3QHB9 G3QHB9 LRAT PTHR46678:SF1 LECITHIN RETINOL ACYLTRANSFERASE LECITHIN RETINOL ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;cellular process#GO:0009987;biological regulation#GO:0065007;hormone metabolic process#GO:0042445 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;rough endoplasmic reticulum#GO:0005791;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000000218.3|UniProtKB=A0A2I2Y9B4 A0A2I2Y9B4 SLC25A11 PTHR45618:SF9 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL 2-OXOGLUTARATE_MALATE CARRIER PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000040069.1|UniProtKB=A0A2I2YCH4 A0A2I2YCH4 PPP1R3B PTHR12307:SF13 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3B protein phosphatase binding#GO:0019903;protein binding#GO:0005515;carbohydrate binding#GO:0030246;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of carbohydrate biosynthetic process#GO:0043255;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000014858.3|UniProtKB=G3RFW7 G3RFW7 NIPAL3 PTHR12570:SF14 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED NIPA-LIKE PROTEIN 3 magnesium ion transport#GO:0015693;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000023917.2|UniProtKB=A0A2I2Y3Q2 A0A2I2Y3Q2 LOC101133361 PTHR10114:SF28 60S RIBOSOMAL PROTEIN L36 RPL36 ALTERNATIVE READING FRAME PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000002862.3|UniProtKB=G3QK50 G3QK50 MFHAS1 PTHR45752:SF48 LEUCINE-RICH REPEAT-CONTAINING MALIGNANT FIBROUS HISTIOCYTOMA-AMPLIFIED SEQUENCE 1 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;inflammatory response#GO:0006954;immune system process#GO:0002376;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;defense response to symbiont#GO:0140546;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological regulation#GO:0065007;response to other organism#GO:0051707;defense response to other organism#GO:0098542;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003441.3|UniProtKB=G3QLM2 G3QLM2 TAS2R60 PTHR11394:SF32 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 60 transmembrane signaling receptor activity#GO:0004888;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038 sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of taste#GO:0050909;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027836.2|UniProtKB=G3RUI4 G3RUI4 MRPL24 PTHR12903:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN UL24M gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014381.3|UniProtKB=G3REN5 G3REN5 PDLIM1 PTHR24214:SF5 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component organization#GO:0016043;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;circulatory system development#GO:0072359;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;heart development#GO:0007507;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;myofibril#GO:0030016;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;stress fiber#GO:0001725;actin filament#GO:0005884;I band#GO:0031674;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;sarcomere#GO:0030017;adherens junction#GO:0005912;cell-cell junction#GO:0005911;Z disc#GO:0030018;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000036571.1|UniProtKB=G3SAV7 G3SAV7 LOC101152760 PTHR11071:SF548 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000006530.3|UniProtKB=G3QUI7 G3QUI7 PTHR10827:SF98 RETICULOCALBIN 45 KDA CALCIUM-BINDING PROTEIN binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calcium-binding protein#PC00060;calmodulin-related#PC00061 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 GORGO|Ensembl=ENSGGOG00000014771.3|UniProtKB=G3S6R8 G3S6R8 CPN1 PTHR11532:SF80 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE N CATALYTIC CHAIN peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 GORGO|Ensembl=ENSGGOG00000000264.3|UniProtKB=G3QDE5 G3QDE5 PHF1 PTHR12628:SF11 POLYCOMB-LIKE TRANSCRIPTION FACTOR PHD FINGER PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000012057.3|UniProtKB=G3R549 G3R549 PTHR14112:SF19 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX3 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000007983.3|UniProtKB=G3QY77 G3QY77 RHEBL1 PTHR24070:SF253 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE RHEBL1 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;GTPase activity#GO:0003924;kinase activator activity#GO:0019209;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;protein kinase activator activity#GO:0030295;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 regulation of TORC1 signaling#GO:1903432;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;positive regulation of TORC1 signaling#GO:1904263;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000000741.3|UniProtKB=A0A2I2ZXJ2 A0A2I2ZXJ2 REC114 PTHR34921:SF1 MEIOTIC RECOMBINATION PROTEIN REC114 MEIOTIC RECOMBINATION PROTEIN REC114 GORGO|Ensembl=ENSGGOG00000037405.1|UniProtKB=A0A2I2ZKN4 A0A2I2ZKN4 PTHR19343:SF12 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 12-3 antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000042087.1|UniProtKB=A0A2I2Z7N4 A0A2I2Z7N4 PYROXD1 PTHR43429:SF2 PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING TRNA LIGASE COMPLEX-ASSOCIATED NAD(P)H DEHYDROGENASE PYROXD1 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009998.3|UniProtKB=G3R3D4 G3R3D4 P2RX2 PTHR10125:SF4 P2X PURINOCEPTOR P2X PURINOCEPTOR 2 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transport#GO:0006810;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000025533.2|UniProtKB=A0A2I2Y7L6 A0A2I2Y7L6 SEMA3E PTHR11036:SF22 SEMAPHORIN SEMAPHORIN-3E signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;chemotaxis#GO:0006935;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;axon guidance#GO:0007411;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000016341.3|UniProtKB=G3RJQ6 G3RJQ6 NWD1 PTHR45013:SF1 NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1 NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000011841.3|UniProtKB=A0A2I2YJC3 A0A2I2YJC3 DIP2A PTHR22754:SF34 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG A catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;sulfur compound metabolic process#GO:0006790;regulation of primary metabolic process#GO:0080090;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;regulation of protein modification process#GO:0031399;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000036673.1|UniProtKB=A0A2I2Z5S8 A0A2I2Z5S8 LEPROT PTHR12050:SF3 LEPTIN RECEPTOR-RELATED LEPTIN RECEPTOR GENE-RELATED PROTEIN transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;membrane#GO:0016020;vesicle membrane#GO:0012506 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010364.3|UniProtKB=G3SII7 G3SII7 MROH7 PTHR23120:SF17 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 7 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000011865.3|UniProtKB=G3R869 G3R869 CCL18 PTHR12015:SF94 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 18 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125 cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;chemotaxis#GO:0006935;chemokine-mediated signaling pathway#GO:0070098;regulation of cell motility#GO:2000145;cell communication#GO:0007154;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of cell migration#GO:0030335;cell migration#GO:0016477;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;response to peptide#GO:1901652;positive regulation of cell motility#GO:2000147;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000016954.3|UniProtKB=G3SB30 G3SB30 RNF121 PTHR13407:SF1 RNF121 PROTEIN E3 UBIQUITIN LIGASE RNF121 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001880.3|UniProtKB=A0A2I2Z2F2 A0A2I2Z2F2 TMEM143 PTHR16095:SF10 TRANSMEMBRANE PROTEIN 143 FAMILY MEMBER TRANSMEMBRANE PROTEIN 143 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000026934.2|UniProtKB=G3SA80 G3SA80 CXCL8 PTHR12015:SF198 SMALL INDUCIBLE CYTOKINE A INTERLEUKIN-8 signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cell chemotaxis#GO:0060326;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;chemotaxis#GO:0006935;inflammatory response#GO:0006954;response to bacterium#GO:0009617;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;cellular response to molecule of bacterial origin#GO:0071219;leukocyte migration#GO:0050900;response to other organism#GO:0051707;cell migration#GO:0016477;immune response#GO:0006955;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;biological process involved in interspecies interaction between organisms#GO:0044419;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;response to molecule of bacterial origin#GO:0002237;response to lipopolysaccharide#GO:0032496;neutrophil chemotaxis#GO:0030593;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;neutrophil migration#GO:1990266;taxis#GO:0042330;response to chemical#GO:0042221;defense response to other organism#GO:0098542;cellular response to lipid#GO:0071396;granulocyte migration#GO:0097530;response to lipid#GO:0033993;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 CCKR signaling map#P06959>IL8#G07296;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856;CCKR signaling map#P06959>IL8#G07001;CCKR signaling map#P06959>IL8#P07136;Interleukin signaling pathway#P00036>Interleukin#P00970 GORGO|Ensembl=ENSGGOG00000011911.3|UniProtKB=A0A2I2ZIF4 A0A2I2ZIF4 NMRK1 PTHR10285:SF126 URIDINE KINASE NICOTINAMIDE RIBOSIDE KINASE 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 nucleotide kinase#PC00172;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000002987.3|UniProtKB=G3SC20 G3SC20 TBC1D30 PTHR22957:SF601 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 30 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000011033.3|UniProtKB=G3R620 G3R620 PTRH1 PTHR17224:SF1 PEPTIDYL-TRNA HYDROLASE PEPTIDYL-TRNA HYDROLASE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 esterase#PC00097;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000011218.3|UniProtKB=G3R6I9 G3R6I9 ASH1L PTHR46147:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000011118.3|UniProtKB=A0A2I2YNF6 A0A2I2YNF6 WNT7B PTHR12027:SF73 WNT RELATED PROTEIN WNT-7B cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;positive regulation of JNK cascade#GO:0046330;cell fate commitment#GO:0045165;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;regulation of JNK cascade#GO:0046328;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;nervous system development#GO:0007399 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206 GORGO|Ensembl=ENSGGOG00000041654.1|UniProtKB=A0A2I2Y506 A0A2I2Y506 MAPK1IP1L PTHR35973:SF1 MAPK-INTERACTING AND SPINDLE-STABILIZING PROTEIN-LIKE MAPK-INTERACTING AND SPINDLE-STABILIZING PROTEIN-LIKE GORGO|Ensembl=ENSGGOG00000005108.3|UniProtKB=G3RZE9 G3RZE9 GP2 PTHR14002:SF16 ENDOGLIN/TGF-BETA RECEPTOR TYPE III PANCREATIC SECRETORY GRANULE MEMBRANE MAJOR GLYCOPROTEIN GP2 cellular process#GO:0009987;neutrophil migration#GO:1990266;cell motility#GO:0048870;granulocyte migration#GO:0097530;cell migration#GO:0016477;immune system process#GO:0002376;leukocyte migration#GO:0050900;myeloid leukocyte migration#GO:0097529 apical part of cell#GO:0045177;extracellular region#GO:0005576;apical plasma membrane#GO:0016324;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008764.3|UniProtKB=G3R084 G3R084 SLC35E4 PTHR11132:SF293 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E4 antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000005736.3|UniProtKB=G3QSI2 G3QSI2 ALOX12B PTHR11771:SF40 LIPOXYGENASE ARACHIDONATE 12-LIPOXYGENASE, 12R-TYPE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;icosanoid metabolic process#GO:0006690;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;lipid modification#GO:0030258;arachidonate metabolic process#GO:0019369;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440 perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000024482.2|UniProtKB=G3RX55 G3RX55 OPRL1 PTHR24229:SF11 NEUROPEPTIDES RECEPTOR NOCICEPTIN RECEPTOR neuropeptide binding#GO:0042923;peptide binding#GO:0042277;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;sensory perception of pain#GO:0019233;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000001264.3|UniProtKB=G3QG02 G3QG02 RBMS1 PTHR24012:SF702 RNA BINDING PROTEIN RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012539.3|UniProtKB=G3R9X8 G3R9X8 NXT1 PTHR12612:SF4 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 1 nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000037665.1|UniProtKB=A0A2I2ZKF5 A0A2I2ZKF5 LOC101151014 PTHR48018:SF51 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5B12 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025631.2|UniProtKB=G3SH76 G3SH76 ANAPC4 PTHR13260:SF0 ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4 ANAPHASE-PROMOTING COMPLEX SUBUNIT 4 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein K11-linked ubiquitination#GO:0070979;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461 GORGO|Ensembl=ENSGGOG00000025376.2|UniProtKB=A0A2I2YP02 A0A2I2YP02 PTHR12610:SF31 SINGLE STRANDED DNA BINDING PROTEIN SINGLE STRANDED DNA BINDING PROTEIN 4 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000005697.3|UniProtKB=G3RT66 G3RT66 ARHGAP1 PTHR45808:SF6 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of cellular process#GO:0048523;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174;VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520 GORGO|Ensembl=ENSGGOG00000005541.3|UniProtKB=G3QS13 G3QS13 SLC5A5 PTHR42985:SF11 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 transport#GO:0006810;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic anion transmembrane transport#GO:0098656 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000012941.3|UniProtKB=G3RWT2 G3RWT2 GAS7 PTHR23065:SF57 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 7 cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;cell projection morphogenesis#GO:0048858;protein-containing complex organization#GO:0043933;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell differentiation#GO:0030154;cell projection organization#GO:0030030;endocytosis#GO:0006897;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;protein-containing complex assembly#GO:0065003;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;clathrin-dependent endocytosis#GO:0072583;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated vesicle#GO:0030136;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000003218.3|UniProtKB=G3QL21 G3QL21 ATOSB PTHR13199:SF12 GH03947P ATOS HOMOLOG PROTEIN B GORGO|Ensembl=ENSGGOG00000011619.3|UniProtKB=G3RQG8 G3RQG8 ADAMTSL5 PTHR13723:SF173 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 5 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000016195.3|UniProtKB=G3RJB3 G3RJB3 SLC30A8 PTHR11562:SF37 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A8 metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915 signal release#GO:0023061;peptide secretion#GO:0002790;secretion#GO:0046903;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;peptide hormone secretion#GO:0030072;protein localization to extracellular region#GO:0071692;metal ion transport#GO:0030001;transport#GO:0006810;response to metal ion#GO:0010038;establishment of localization#GO:0051234;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;macromolecule localization#GO:0033036;response to glucose#GO:0009749;insulin secretion#GO:0030073;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;response to monosaccharide#GO:0034284;transition metal ion transport#GO:0000041;response to oxygen-containing compound#GO:1901700;zinc ion transmembrane transport#GO:0071577;transmembrane transport#GO:0055085;protein secretion#GO:0009306;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;hormone secretion#GO:0046879;protein transport#GO:0015031;response to carbohydrate#GO:0009743;secretion by cell#GO:0032940;response to hexose#GO:0009746;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;export from cell#GO:0140352;signaling#GO:0023052;hormone transport#GO:0009914;cellular process#GO:0009987;establishment of protein localization#GO:0045184;response to chemical#GO:0042221;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011809.3|UniProtKB=G3R826 G3R826 RAD21 PTHR12585:SF20 SCC1 / RAD21 FAMILY MEMBER DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21 HOMOLOG chromatin binding#GO:0003682;binding#GO:0005488 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;sister chromatid cohesion#GO:0007062;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cell cycle#GO:0007049;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;organelle organization#GO:0006996;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cohesin complex#GO:0008278;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000034832.2|UniProtKB=G3SKR8 G3SKR8 PTHR21315:SF2 APRATAXIN AND PNK-LIKE FACTOR-RELATED APRATAXIN AND PNK-LIKE FACTOR catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000043878.1|UniProtKB=G3R7U5 G3R7U5 NSUN5 PTHR22807:SF4 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 rRNA modification#GO:0000154;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;positive regulation of protein metabolic process#GO:0051247;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA metabolic process#GO:0016070;methylation#GO:0032259;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of protein metabolic process#GO:0051246;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;rRNA base methylation#GO:0070475;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;positive regulation of biosynthetic process#GO:0009891;rRNA processing#GO:0006364;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;rRNA metabolic process#GO:0016072;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000043401.1|UniProtKB=A0A2I2YCE0 A0A2I2YCE0 HTR2C PTHR24247:SF32 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2C signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;trans-synaptic signaling#GO:0099537;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186 dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414 GORGO|Ensembl=ENSGGOG00000000724.3|UniProtKB=G3QEL7 G3QEL7 COL4A4 PTHR24023:SF714 COLLAGEN ALPHA COLLAGEN ALPHA-4(IV) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;basement membrane#GO:0005604;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000000786.3|UniProtKB=A0A2I2YYY4 A0A2I2YYY4 DISP1 PTHR45951:SF4 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED HOMOLOG 1 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;smoothened signaling pathway#GO:0007224;cell communication#GO:0007154 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001125.3|UniProtKB=A0A2I2YU52 A0A2I2YU52 SPACA3 PTHR11407:SF25 LYSOZYME C SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 3 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;lysozyme activity#GO:0003796;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;cellular process#GO:0009987;single fertilization#GO:0007338;reproductive process#GO:0022414;fertilization#GO:0009566;cellular process involved in reproduction in multicellular organism#GO:0022412 cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;acrosomal vesicle#GO:0001669;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;cytoplasm#GO:0005737;secretory vesicle#GO:0099503 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000014511.3|UniProtKB=A0A2I2Y3P0 A0A2I2Y3P0 PTHR21148:SF11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000016958.3|UniProtKB=G3RLA7 G3RLA7 PTHR22765:SF39 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF149 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endosome#GO:0005768;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;late endosome#GO:0005770;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002582.3|UniProtKB=G3QJF5 G3QJF5 KIF15 PTHR24115:SF1004 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF15 ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000003435.3|UniProtKB=A0A2I2ZII1 A0A2I2ZII1 GRAMD2B PTHR46645:SF2 GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED GRAM DOMAIN-CONTAINING PROTEIN 2B microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000002414.3|UniProtKB=G3QJ01 G3QJ01 CPA5 PTHR11705:SF16 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A5 metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000040883.1|UniProtKB=A0A2I2YKY0 A0A2I2YKY0 PALM2AKAP2 PTHR10498:SF10 PARALEMMIN-RELATED PALM2-AKAP2 FUSION GORGO|Ensembl=ENSGGOG00000005081.3|UniProtKB=G3S2X8 G3S2X8 NOD1 PTHR24107:SF4 YNEIN REGULATORY COMPLEX SUBUNIT 5 NOD1 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000004133.3|UniProtKB=G3QNE4 G3QNE4 ASIC1 PTHR11690:SF170 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 1 sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023490.2|UniProtKB=G3RR42 G3RR42 NTSR2 PTHR24243:SF10 G-PROTEIN COUPLED RECEPTOR NEUROTENSIN RECEPTOR TYPE 2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000022094.2|UniProtKB=G3RYP5 G3RYP5 LOC101135429 PTHR19971:SF37 SIGNAL-REGULATORY PROTEIN BETA TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 positive regulation of cellular component organization#GO:0051130;positive regulation of lymphocyte activation#GO:0051251;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;positive regulation of cell adhesion#GO:0045785;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of endocytosis#GO:0030100;positive regulation of leukocyte activation#GO:0002696;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of multicellular organismal process#GO:0051239;positive regulation of cell activation#GO:0050867;positive regulation of endocytosis#GO:0045807;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;regulation of cell adhesion#GO:0030155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010455.3|UniProtKB=G3R4J1 G3R4J1 PTHR18945:SF831 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-3 transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;acetylcholine receptor activity#GO:0015464;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;transport#GO:0006810;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;neuromuscular synaptic transmission#GO:0007274;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789 transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA3#P06595;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 GORGO|Ensembl=ENSGGOG00000005992.3|UniProtKB=G3QT56 G3QT56 ICAM5 PTHR13771:SF19 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 5 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;leukocyte cell-cell adhesion#GO:0007159;cell adhesion#GO:0007155;cell adhesion mediated by integrin#GO:0033627 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000014936.3|UniProtKB=G3RG40 G3RG40 ARHGAP10 PTHR12552:SF5 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 10 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067;organelle organization#GO:0006996;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GTPase-activating protein#PC00257 Integrin signalling pathway#P00034>GRAF#P00926;PDGF signaling pathway#P00047>Rho#P01174 GORGO|Ensembl=ENSGGOG00000009656.3|UniProtKB=G3R2H7 G3R2H7 LGALS9C PTHR11346:SF80 GALECTIN GALECTIN-9B carbohydrate binding#GO:0030246;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 regulation of lymphocyte activation#GO:0051249;negative regulation of metabolic process#GO:0009892;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;regulation of T cell activation#GO:0050863;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of cell-cell adhesion#GO:0022408;positive regulation of biological process#GO:0048518;regulation of mononuclear cell proliferation#GO:0032944;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of T cell proliferation#GO:0042129;regulation of macromolecule metabolic process#GO:0060255;negative regulation of multicellular organismal process#GO:0051241;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;negative regulation of T cell activation#GO:0050868;negative regulation of biosynthetic process#GO:0009890;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;negative regulation of cell activation#GO:0050866;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000001363.3|UniProtKB=G3QG92 G3QG92 PRL PTHR11417:SF5 SOMATOTROPIN,PROLACTIN PROLACTIN binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;anatomical structure development#GO:0048856;regulation of secretion#GO:0051046;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;reproductive process#GO:0022414;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell surface receptor signaling pathway#GO:0007166;regulation of localization#GO:0032879;regulation of transport#GO:0051049;animal organ development#GO:0048513;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;positive regulation of multicellular organismal process#GO:0051240;multi-multicellular organism process#GO:0044706;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>Prolactin#P06789 GORGO|Ensembl=ENSGGOG00000023439.2|UniProtKB=G3SHV9 G3SHV9 KRTAP29-1 PTHR23262:SF91 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 29-1 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000014841.3|UniProtKB=A0A2I2ZI28 A0A2I2ZI28 TBC1D23 PTHR13297:SF10 TBC1 DOMAIN FAMILY MEMBER 23-RELATED TBC1 DOMAIN FAMILY MEMBER 23 cytosolic transport#GO:0016482;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;localization#GO:0051179;anatomical structure development#GO:0048856;cellular localization#GO:0051641;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;embryo development#GO:0009790;intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;animal organ development#GO:0048513;endosomal transport#GO:0016197 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000005339.3|UniProtKB=G3SJR8 G3SJR8 DHX37 PTHR18934:SF99 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX37-RELATED RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000022803.2|UniProtKB=G3RPG2 G3RPG2 ARMC1 PTHR28592:SF3 ARMADILLO REPEAT-CONTAINING PROTEIN 1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000023087.2|UniProtKB=A0A2I2YK18 A0A2I2YK18 PTHR24062:SF146 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 3 binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000028046.2|UniProtKB=G3RW72 G3RW72 SLC25A20 PTHR45624:SF56 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL CARNITINE_ACYLCARNITINE CARRIER PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;quaternary ammonium group transmembrane transporter activity#GO:0015651 quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular localization#GO:0051641 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007441.3|UniProtKB=G3QWV9 G3QWV9 FBXW2 PTHR44436:SF1 F-BOX/WD REPEAT-CONTAINING PROTEIN 2 F-BOX_WD REPEAT-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000041672.1|UniProtKB=A0A2I2Y3I2 A0A2I2Y3I2 TRIQK PTHR20583:SF1 TRIPLE QXXK/R MOTIF-CONTAINING PROTEIN TRIPLE QXXK_R MOTIF-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000009737.3|UniProtKB=G3R2Q1 G3R2Q1 E2F5 PTHR12081:SF35 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F5 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000040865.1|UniProtKB=A0A2I2Z3M8 A0A2I2Z3M8 PTHR24226:SF2 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 G PROTEIN-COUPLED ESTROGEN RECEPTOR 1 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;transcription regulator activity#GO:0140110;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;lipid binding#GO:0008289;G protein-coupled receptor activity#GO:0004930;steroid binding#GO:0005496;signaling receptor activity#GO:0038023 positive regulation of response to stimulus#GO:0048584;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;intracellular receptor signaling pathway#GO:0030522;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to steroid hormone#GO:0048545;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;regulation of ERK1 and ERK2 cascade#GO:0070372;response to estradiol#GO:0032355;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to steroid hormone stimulus#GO:0071383;regulation of MAPK cascade#GO:0043408;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;estrogen receptor signaling pathway#GO:0030520;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000010931.3|UniProtKB=A0A2I2ZU21 A0A2I2ZU21 EMC4 PTHR19315:SF9 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000003803.3|UniProtKB=G3QMJ4 G3QMJ4 BMP7 PTHR11848:SF135 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 7 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 multicellular organismal process#GO:0032501;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;response to BMP#GO:0071772;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP7#G06687;Gonadotropin-releasing hormone receptor pathway#P06664>BMP7#G06901;Gonadotropin-releasing hormone receptor pathway#P06664>BMP6/7#P06752;TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000005575.3|UniProtKB=A0A2I2ZKD9 A0A2I2ZKD9 MPIG6B PTHR37347:SF1 MEGAKARYOCYTE AND PLATELET INHIBITORY RECEPTOR G6B MEGAKARYOCYTE AND PLATELET INHIBITORY RECEPTOR G6B regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;negative regulation of cell-cell adhesion#GO:0022408;cellular process#GO:0009987;signal transduction#GO:0007165;coagulation#GO:0050817;response to stress#GO:0006950;regulation of response to wounding#GO:1903034;negative regulation of response to wounding#GO:1903035;cell surface receptor signaling pathway#GO:0007166;regulation of wound healing#GO:0061041;signaling#GO:0023052;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;response to stimulus#GO:0050896;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;wound healing#GO:0042060;regulation of biological quality#GO:0065008;negative regulation of coagulation#GO:0050819;negative regulation of hemostasis#GO:1900047;regulation of signaling#GO:0023051;regulation of platelet aggregation#GO:0090330;negative regulation of signaling#GO:0023057;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of coagulation#GO:0050818;regulation of hemostasis#GO:1900046;response to wounding#GO:0009611;negative regulation of wound healing#GO:0061045;blood coagulation#GO:0007596;negative regulation of cell activation#GO:0050866;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;negative regulation of blood coagulation#GO:0030195;regulation of cell communication#GO:0010646;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;hemostasis#GO:0007599;negative regulation of multicellular organismal process#GO:0051241;cell communication#GO:0007154;regulation of platelet activation#GO:0010543 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005517.3|UniProtKB=G3QRY8 G3QRY8 AARS PTHR11777:SF8 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;deacylase activity#GO:0160215;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689 tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000036722.1|UniProtKB=A0A2I2Y220 A0A2I2Y220 SPOCK3 PTHR13866:SF21 SPARC OSTEONECTIN TESTICAN-3 peptidase regulator activity#GO:0061134;calcium ion binding#GO:0005509;endopeptidase regulator activity#GO:0061135;ion binding#GO:0043167;binding#GO:0005488;peptidase inhibitor activity#GO:0030414;small molecule binding#GO:0036094;molecular function inhibitor activity#GO:0140678;cation binding#GO:0043169;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 regulation of biological process#GO:0050789;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000005009.3|UniProtKB=A0A2I2ZTR8 A0A2I2ZTR8 MCM3 PTHR11630:SF106 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM3 nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853 cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cell cycle process#GO:0022402;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA strand elongation involved in DNA replication#GO:0006271;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA replication initiation#GO:0006270;DNA repair#GO:0006281;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;mitotic cell cycle process#GO:1903047;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;MCM complex#GO:0042555;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000008830.3|UniProtKB=A0A2I2YWD3 A0A2I2YWD3 PPP1R3C PTHR12307:SF15 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3C phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247;binding#GO:0005488;enzyme binding#GO:0019899;carbohydrate binding#GO:0030246;protein binding#GO:0005515;protein phosphatase binding#GO:0019903 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000039918.1|UniProtKB=A0A2I2Z2Y5 A0A2I2Z2Y5 PTHR12398:SF35 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE INHIBITOR 2-RELATED enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 phosphatase inhibitor#PC00183 GORGO|Ensembl=ENSGGOG00000001812.3|UniProtKB=A0A2I2Y1V4 A0A2I2Y1V4 FOXO4 PTHR45767:SF3 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 PI3 kinase pathway#P00048>FOXO#P01198 GORGO|Ensembl=ENSGGOG00000036507.1|UniProtKB=A0A2I2Z4M5 A0A2I2Z4M5 PTHR10792:SF44 60S RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN EL24 mRNA binding#GO:0003729;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000036656.1|UniProtKB=A0A2I2YQ86 A0A2I2YQ86 PTHR21255:SF51 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 1 protein binding#GO:0005515;binding#GO:0005488 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 organelle#GO:0043226;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000008278.3|UniProtKB=G3QYY8 G3QYY8 ACTL7B PTHR11937:SF59 ACTIN ACTIN-LIKE PROTEIN 7B structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000015194.3|UniProtKB=G3RGT2 G3RGT2 CADPS PTHR12166:SF6 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR 1 cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;transport#GO:0006810;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;export from cell#GO:0140352;regulation of cellular process#GO:0050794;positive regulation of secretion#GO:0051047;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;secretion#GO:0046903;localization#GO:0051179;regulation of secretion#GO:0051046 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000010148.3|UniProtKB=G3R3S8 G3R3S8 PITPNM1 PTHR10658:SF40 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN MEMBRANE-ASSOCIATED PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1 intramembrane lipid carrier activity#GO:0140303;cation binding#GO:0043169;small molecule binding#GO:0036094;anion binding#GO:0043168;lipid carrier activity#GO:0005319;phosphatidylcholine intramembrane carrier activity#GO:0008525;ion binding#GO:0043167;phosphatidylcholine binding#GO:0031210;phosphatidylinositol transfer activity#GO:0008526;phospholipid binding#GO:0005543;phosphatidylinositol binding#GO:0035091;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;binding#GO:0005488;molecular carrier activity#GO:0140104;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000010571.3|UniProtKB=G3R4V2 G3R4V2 GALNT16 PTHR11675:SF3 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 16 catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000006443.3|UniProtKB=G3QU99 G3QU99 LOC101152033 PTHR24384:SF110 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 730-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000024638.2|UniProtKB=G3SK26 G3SK26 ZC3H12B PTHR12876:SF27 N4BP1-RELATED RIBONUCLEASE ZC3H12B-RELATED endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000040488.1|UniProtKB=A0A2I2ZPB8 A0A2I2ZPB8 FTCDNL1 PTHR12234:SF1 FORMIMINOTRANSFERASE-CYCLODEAMINASE FORMIMINOTRANSFERASE N-TERMINAL SUBDOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824 GORGO|Ensembl=ENSGGOG00000017056.3|UniProtKB=G3RLJ5 G3RLJ5 TMEM144 PTHR16119:SF17 TRANSMEMBRANE PROTEIN 144 TRANSMEMBRANE PROTEIN 144 GORGO|Ensembl=ENSGGOG00000010763.3|UniProtKB=G3SGT4 G3SGT4 UNC45B PTHR45994:SF2 FI21225P1 PROTEIN UNC-45 HOMOLOG B heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;binding#GO:0005488;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000010464.3|UniProtKB=G3R4K0 G3R4K0 BARX1 PTHR24330:SF12 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN BARH-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000024224.2|UniProtKB=G3S3Z1 G3S3Z1 SYT1 PTHR10024:SF239 SYNAPTOTAGMIN SYNAPTOTAGMIN-1 protein binding#GO:0005515;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 positive regulation of cellular process#GO:0048522;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;synaptic signaling#GO:0099536;cellular process#GO:0009987;positive regulation of transport#GO:0051050;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular component organization#GO:0051128;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;export from cell#GO:0140352;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;axon#GO:0030424;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;organelle membrane#GO:0031090;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 GORGO|Ensembl=ENSGGOG00000027739.2|UniProtKB=G3S3C9 G3S3C9 RPL22 PTHR10064:SF2 60S RIBOSOMAL PROTEIN L22 LARGE RIBOSOMAL SUBUNIT PROTEIN EL22 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009685.3|UniProtKB=G3R2K5 G3R2K5 CCDC25 PTHR13049:SF8 DUF814-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 25 GORGO|Ensembl=ENSGGOG00000000104.3|UniProtKB=G3QD02 G3QD02 ZNF256 PTHR24381:SF373 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 256 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000042556.1|UniProtKB=A0A2I2YMD7 A0A2I2YMD7 PTHR22526:SF3 ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED ANAPHASE PROMOTING COMPLEX SUBUNIT 15 regulation of cell communication#GO:0010646;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of nuclear division#GO:0051783;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;regulation of response to stimulus#GO:0048583;regulation of chromosome segregation#GO:0051983;regulation of chromosome organization#GO:0033044 nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000008307.3|UniProtKB=G3QZ20 G3QZ20 BARHL1 PTHR24330:SF8 HOMEOBOX PROTEIN BARH-LIKE BARH-LIKE 1 HOMEOBOX PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000009633.3|UniProtKB=A0A2I2YYL4 A0A2I2YYL4 RFX2 PTHR12619:SF17 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;spermatid development#GO:0007286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000013125.3|UniProtKB=G3RBF8 G3RBF8 MYO1A PTHR13140:SF291 MYOSIN UNCONVENTIONAL MYOSIN-IA cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;actin filament organization#GO:0007015;transport#GO:0006810;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based movement#GO:0030048;localization#GO:0051179;supramolecular fiber organization#GO:0097435;nervous system process#GO:0050877;actin filament-based process#GO:0030029;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;sensory perception of sound#GO:0007605;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell periphery#GO:0071944;brush border#GO:0005903;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000001834.3|UniProtKB=G3QHH8 G3QHH8 HRNR PTHR22571:SF25 FILAGGRIN-RELATED HORNERIN animal organ development#GO:0048513;anatomical structure development#GO:0048856;developmental process#GO:0032502;epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108;skin development#GO:0043588;tissue development#GO:0009888;epithelium development#GO:0060429 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000006988.4|UniProtKB=G3QVQ9 G3QVQ9 HNF4A PTHR24083:SF41 NUCLEAR HORMONE RECEPTOR HEPATOCYTE NUCLEAR FACTOR 4-ALPHA DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000005158.3|UniProtKB=A0A2I2YQS5 A0A2I2YQS5 PALS2 PTHR23122:SF45 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PROTEIN PALS2 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004667.3|UniProtKB=G3QPS2 G3QPS2 KLF3 PTHR23235:SF48 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006944.3|UniProtKB=A0A2I2ZE11 A0A2I2ZE11 PTHR13952:SF11 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD RNA-BINDING MOTIF PROTEIN, X-LINKED-LIKE-2 snRNA binding#GO:0017069;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000003754.3|UniProtKB=G3QME9 G3QME9 LGALS2 PTHR11346:SF104 GALECTIN GALECTIN-2 carbohydrate binding#GO:0030246;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000027886.2|UniProtKB=G3S4Q6 G3S4Q6 PTHR15298:SF20 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000000633.3|UniProtKB=G3QED1 G3QED1 PTHR12668:SF56 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14DP cellular process#GO:0009987;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000009465.3|UniProtKB=G3R219 G3R219 TANC1 PTHR24166:SF23 ROLLING PEBBLES, ISOFORM B PROTEIN TANC1 regulation of synapse organization#GO:0050807;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007 postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;glutamatergic synapse#GO:0098978;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;cell junction#GO:0030054;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000038513.1|UniProtKB=A0A2I2Y7I1 A0A2I2Y7I1 PTHR10292:SF11 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN LINKER DOMAIN-CONTAINING PROTEIN 1 clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 clathrin coat#GO:0030118;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000010597.3|UniProtKB=G3R506 G3R506 MTOR PTHR11139:SF134 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE MTOR transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;negative regulation of catabolic process#GO:0009895;cell communication#GO:0007154;TORC1 signaling#GO:0038202;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;TORC2 signaling#GO:0038203;regulation of autophagy#GO:0010506;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of macroautophagy#GO:0016241;negative regulation of autophagy#GO:0010507;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of macroautophagy#GO:0016242;regulation of metabolic process#GO:0019222;TOR signaling#GO:0031929;biological regulation#GO:0065007 TOR complex#GO:0038201;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway by glucose deprivation#P04397>mTOR#P04638;PDGF signaling pathway#P00047>mTOR#P01144;Interleukin signaling pathway#P00036>mTOR#P00966;Hypoxia response via HIF activation#P00030>TOR#P00817 GORGO|Ensembl=ENSGGOG00000000591.3|UniProtKB=G3QE89 G3QE89 LZTS1 PTHR19354:SF5 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 1-RELATED regulation of synaptic plasticity#GO:0048167;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of neuron projection development#GO:0010975;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;regulation of dendrite morphogenesis#GO:0048814;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;modulation of chemical synaptic transmission#GO:0050804;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646 cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;postsynapse#GO:0098794;dendritic spine#GO:0043197;neuron projection#GO:0043005 GORGO|Ensembl=ENSGGOG00000025471.2|UniProtKB=G3RNX0 G3RNX0 KHDC1L PTHR31368:SF5 DEVELOPMENT PLURPOTENCY-ASSOCIATED PROTEIN 1/5 FAMILY MEMBER KHDC1-LIKE PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008273.3|UniProtKB=G3QYZ0 G3QYZ0 NLRP13 PTHR45690:SF16 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 13 regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of biological process#GO:0050789;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000006371.3|UniProtKB=A0A2I2YCW1 A0A2I2YCW1 ZNF418 PTHR23226:SF432 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016767.3|UniProtKB=G3RKT0 G3RKT0 MASTL PTHR24356:SF438 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE GREATWALL catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000027136.2|UniProtKB=G3S503 G3S503 PSMD2 PTHR10943:SF11 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endopeptidase complex#GO:1905369;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;proteasome complex#GO:0000502;nucleus#GO:0005634;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 GORGO|Ensembl=ENSGGOG00000014862.3|UniProtKB=A0A2I2Y3X1 A0A2I2Y3X1 IL7R PTHR23037:SF27 CYTOKINE RECEPTOR INTERLEUKIN-7 RECEPTOR SUBUNIT ALPHA cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 interleukin-7-mediated signaling pathway#GO:0038111;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;regulation of signaling#GO:0023051;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;cell development#GO:0048468;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;hemopoiesis#GO:0030097;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;anatomical structure development#GO:0048856;cytokine-mediated signaling pathway#GO:0019221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010399.3|UniProtKB=G3R4F4 G3R4F4 SLC9C2 PTHR10110:SF91 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 11 active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000027377.2|UniProtKB=G3S9C7 G3S9C7 CRYBG3 PTHR11818:SF38 BETA/GAMMA CRYSTALLIN VERY LARGE A-KINASE ANCHOR PROTEIN structural molecule activity#GO:0005198 sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000011459.3|UniProtKB=G3R746 G3R746 VMO1 PTHR18841:SF2 VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED VITELLINE MEMBRANE OUTER LAYER PROTEIN 1 HOMOLOG extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000038190.1|UniProtKB=A0A2I2YAQ2 A0A2I2YAQ2 PTHR14256:SF4 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE SUBUNIT FA4 transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;transporter complex#GO:1990351;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000012056.3|UniProtKB=G3R8P5 G3R8P5 NCMAP PTHR35974:SF1 NONCOMPACT MYELIN-ASSOCIATED PROTEIN NONCOMPACT MYELIN-ASSOCIATED PROTEIN structural molecule activity#GO:0005198 cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;peripheral nervous system development#GO:0007422;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell development#GO:0048468;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;gliogenesis#GO:0042063;myelination#GO:0042552;neurogenesis#GO:0022008;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;nervous system development#GO:0007399 main axon#GO:0044304;axon#GO:0030424;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;myelin sheath#GO:0043209;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 myelin protein#PC00161;structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000016771.3|UniProtKB=G3RKT1 G3RKT1 HAX1 PTHR14938:SF2 HCLS1-ASSOCIATED PROTEIN X-1 HCLS1-ASSOCIATED PROTEIN X-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 regulation of actin filament-based process#GO:0032970;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;cell surface receptor signaling pathway#GO:0007166;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of actin cytoskeleton organization#GO:0032956;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;response to peptide#GO:1901652;regulation of organelle organization#GO:0033043;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896 clathrin-coated vesicle#GO:0030136;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;cell periphery#GO:0071944;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;mitochondrion#GO:0005739;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000036769.1|UniProtKB=A0A2I2YVH2 A0A2I2YVH2 TPD52 PTHR19307:SF12 TUMOR PROTEIN D52 TUMOR PROTEIN D52 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;hemopoiesis#GO:0030097;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;developmental process#GO:0032502;B cell activation#GO:0042113;cellular developmental process#GO:0048869;mononuclear cell differentiation#GO:1903131;regulation of biological process#GO:0050789;leukocyte differentiation#GO:0002521;leukocyte activation#GO:0045321;positive regulation of cell population proliferation#GO:0008284;cell development#GO:0048468;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;immune system process#GO:0002376;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000014154.3|UniProtKB=G3RE43 G3RE43 HSPA9 PTHR19375:SF184 HEAT SHOCK PROTEIN 70KDA STRESS-70 PROTEIN, MITOCHONDRIAL ribonucleoside triphosphate phosphatase activity#GO:0017111;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 protein metabolic process#GO:0019538;protein refolding#GO:0042026;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein folding#GO:0006457;iron-sulfur cluster assembly#GO:0016226;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Hsp70 family chaperone#PC00027;chaperone#PC00072 Parkinson disease#P00049>Hsp70#P01208 GORGO|Ensembl=ENSGGOG00000007874.3|UniProtKB=G3QXY3 G3QXY3 LOC101144859 PTHR11972:SF60 NADPH OXIDASE NADPH OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664 cellular process#GO:0009987;metabolic process#GO:0008152;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;defense response#GO:0006952;superoxide metabolic process#GO:0006801;response to stimulus#GO:0050896 catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000016737.3|UniProtKB=A0A2I2ZMM2 A0A2I2ZMM2 PRR16 PTHR15917:SF0 FAMILY NOT NAMED PROTEIN LARGEN regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;post-transcriptional regulation of gene expression#GO:0010608;regulation of anatomical structure size#GO:0090066;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090 GORGO|Ensembl=ENSGGOG00000011814.3|UniProtKB=G3R832 G3R832 CCDC191 PTHR22028:SF5 SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 191 enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;protein binding#GO:0005515 GORGO|Ensembl=ENSGGOG00000009002.3|UniProtKB=G3R0V4 G3R0V4 MTFR2 PTHR14215:SF2 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 2 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000022607.2|UniProtKB=A0A2I2ZN12 A0A2I2ZN12 CIAPIN1 PTHR13273:SF17 ANAMORSIN ANAMORSIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000004129.3|UniProtKB=G3QNE3 G3QNE3 CCDC88B PTHR18947:SF35 HOOK PROTEINS COILED-COIL DOMAIN-CONTAINING PROTEIN 88B protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cytoplasmic microtubule organization#GO:0031122;cellular component organization#GO:0016043;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization#GO:0051179;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015821.3|UniProtKB=G3RID1 G3RID1 PTHR24242:SF253 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000015868.3|UniProtKB=G3RIH5 G3RIH5 INSIG2 PTHR15301:SF10 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE 2 PROTEIN signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;response to endogenous stimulus#GO:0009719;regulation of cellular response to stress#GO:0080135;negative regulation of intracellular signal transduction#GO:1902532;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;response to chemical#GO:0042221;response to lipid#GO:0033993;response to hormone#GO:0009725;response to stress#GO:0006950;metabolic process#GO:0008152;cellular response to peptide hormone stimulus#GO:0071375;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;regulation of signal transduction#GO:0009966;cellular response to nitrogen compound#GO:1901699;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;regulation of response to stress#GO:0080134;secondary alcohol metabolic process#GO:1902652;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;cellular localization#GO:0051641;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;negative regulation of signal transduction#GO:0009968;cholesterol biosynthetic process#GO:0006695;cellular response to lipid#GO:0071396;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;alcohol metabolic process#GO:0006066;regulation of cell communication#GO:0010646;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;SREBP signaling pathway#GO:0032933;lipid biosynthetic process#GO:0008610;negative regulation of response to stimulus#GO:0048585;secondary alcohol biosynthetic process#GO:1902653;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;cholesterol metabolic process#GO:0008203;negative regulation of cellular process#GO:0048523 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000000925.3|UniProtKB=G3QF49 G3QF49 AZU1 PTHR24271:SF10 KALLIKREIN-RELATED AZUROCIDIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000006994.3|UniProtKB=G3QVR5 G3QVR5 CUEDC2 PTHR12493:SF0 CUE DOMAIN CONTAINING 2 CUE DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000028301.2|UniProtKB=G3S0Q9 G3S0Q9 PTHR24230:SF78 G-PROTEIN COUPLED RECEPTOR KISS-1 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 regulation of transport#GO:0051049;regulation of localization#GO:0032879;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of hormone secretion#GO:0046883;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000008655.3|UniProtKB=G3QZY3 G3QZY3 EXTL3 PTHR11062:SF73 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 3 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000041625.1|UniProtKB=A0A2I2Y4W8 A0A2I2Y4W8 PTHR13180:SF0 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50B cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 GORGO|Ensembl=ENSGGOG00000011953.3|UniProtKB=G3R8F2 G3R8F2 NUDT8 PTHR12992:SF11 NUDIX HYDROLASE MITOCHONDRIAL COENZYME A DIPHOSPHATASE NUDT8 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000013845.3|UniProtKB=G3S3B0 G3S3B0 RHBDL1 PTHR45840:SF4 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 GORGO|Ensembl=ENSGGOG00000024168.2|UniProtKB=A0A2I2ZVQ3 A0A2I2ZVQ3 PTHR23001:SF21 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2 translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743;translation initiation factor binding#GO:0031369;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;protein binding#GO:0005515 protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;cytoplasmic translational initiation#GO:0002183;translational initiation#GO:0006413;translation#GO:0006412;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000010636.3|UniProtKB=G3R503 G3R503 IP6K1 PTHR12400:SF73 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;organophosphate metabolic process#GO:0019637;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;glycerophospholipid biosynthetic process#GO:0046474;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000016101.4|UniProtKB=G3RJ50 G3RJ50 ABCA9 PTHR19229:SF120 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 9 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000013221.3|UniProtKB=G3RBN4 G3RBN4 ORMDL2 PTHR12665:SF13 ORMDL PROTEINS ORM1-LIKE PROTEIN 2 ceramide metabolic process#GO:0006672;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;cellular process#GO:0009987 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000006875.3|UniProtKB=G3QVF9 G3QVF9 ZMYND19 PTHR46831:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000000819.3|UniProtKB=G3QEV5 G3QEV5 SCGB1D4 PTHR11332:SF11 SECRETOGLOBIN FAMILY 1D SECRETOGLOBIN FAMILY 1D MEMBER 4 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000009463.3|UniProtKB=G3R213 G3R213 ABCD2 PTHR11384:SF24 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 2 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ATP binding#GO:0005524;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;nucleotide binding#GO:0000166;monocarboxylic acid transmembrane transporter activity#GO:0008028;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;carboxylic acid transmembrane transporter activity#GO:0046943 organelle organization#GO:0006996;lipid catabolic process#GO:0016042;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;fatty acid oxidation#GO:0019395;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;cellular component organization#GO:0016043;cellular localization#GO:0051641;transmembrane transport#GO:0055085;fatty acid catabolic process#GO:0009062;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;peroxisome organization#GO:0007031;lipid transport#GO:0006869;monocarboxylic acid catabolic process#GO:0072329;macromolecule localization#GO:0033036;carboxylic acid catabolic process#GO:0046395;lipid modification#GO:0030258;establishment of localization#GO:0051234;fatty acid metabolic process#GO:0006631;intracellular transport#GO:0046907;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;transport#GO:0006810;catabolic process#GO:0009056;carboxylic acid transmembrane transport#GO:1905039;primary metabolic process#GO:0044238;fatty acid transport#GO:0015908;localization#GO:0051179;lipid oxidation#GO:0034440;monocarboxylic acid transport#GO:0015718;peroxisomal transport#GO:0043574 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000007692.3|UniProtKB=G3QXI3 G3QXI3 IQSEC2 PTHR10663:SF314 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 2 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of signaling#GO:0023051;regulation of endocytosis#GO:0030100;regulation of biological quality#GO:0065008;regulation of transport#GO:0051049;regulation of localization#GO:0032879 plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000014044.3|UniProtKB=G3RDU5 G3RDU5 CIITA PTHR47189:SF1 MHC CLASS II TRANSACTIVATOR MHC CLASS II TRANSACTIVATOR positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355 GORGO|Ensembl=ENSGGOG00000004409.3|UniProtKB=G3S4K1 G3S4K1 DPYSL3 PTHR11647:SF57 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 3 dihydropyrimidinase activity#GO:0004157;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleobase catabolic process#GO:0046113;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;actin cytoskeleton organization#GO:0030036;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;actin filament organization#GO:0007015;nucleobase metabolic process#GO:0009112;cellular component organization or biogenesis#GO:0071840;pyrimidine nucleobase metabolic process#GO:0006206;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;cytoskeleton organization#GO:0007010 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 GORGO|Ensembl=ENSGGOG00000011735.3|UniProtKB=G3R7U7 G3R7U7 ZBTB3 PTHR24394:SF19 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000003724.3|UniProtKB=G3QMC6 G3QMC6 NIT2 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000003811.3|UniProtKB=G3QMK4 G3QMK4 EREG PTHR10740:SF11 TRANSFORMING GROWTH FACTOR ALPHA PROEPIREGULIN molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851 positive regulation of cell population proliferation#GO:0008284;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of cell cycle#GO:0051726;positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of mitotic cell cycle#GO:0007346;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of cell cycle#GO:0045787;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840;regulation of mitotic nuclear division#GO:0007088 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 GORGO|Ensembl=ENSGGOG00000003017.3|UniProtKB=G3QKJ0 G3QKJ0 IL1RAPL1 PTHR11890:SF22 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 1 regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of cellular process#GO:0048523;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;response to stimulus#GO:0050896;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007128.3|UniProtKB=G3QW25 G3QW25 LOC101127828 PTHR15422:SF21 OS05G0565100 PROTEIN TRANSMEMBRANE REDUCTASE CYB561D2 tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;binding#GO:0005488;catalytic activity#GO:0003824 chemical homeostasis#GO:0048878;carbohydrate homeostasis#GO:0033500;homeostatic process#GO:0042592 GORGO|Ensembl=ENSGGOG00000006066.3|UniProtKB=G3QTD4 G3QTD4 OSBPL1A PTHR10972:SF53 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 1 alcohol binding#GO:0043178;steroid binding#GO:0005496;lipid binding#GO:0008289;cholesterol binding#GO:0015485;binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934 cytosol#GO:0005829;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000001769.3|UniProtKB=G3RU80 G3RU80 CLK3 PTHR45646:SF10 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK3 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000013902.3|UniProtKB=G3RDF6 G3RDF6 FBXL16 PTHR13318:SF193 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 16 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 transferase complex#GO:1990234;catalytic complex#GO:1902494;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000011730.3|UniProtKB=G3RI68 G3RI68 LOC101131844 PTHR22807:SF4 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;methylation#GO:0032259;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;rRNA base methylation#GO:0070475;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396;positive regulation of biosynthetic process#GO:0009891;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;positive regulation of translation#GO:0045727;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000016308.3|UniProtKB=G3RJM2 G3RJM2 SETDB1 PTHR46024:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE SETDB1 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000004875.3|UniProtKB=G3QQB3 G3QQB3 ZNF710 PTHR24390:SF43 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 710 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000012913.3|UniProtKB=G3RAV9 G3RAV9 LOC101153542 PTHR48002:SF182 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C46 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000017145.3|UniProtKB=G3RLS0 G3RLS0 ZNF319 PTHR24377:SF838 IP01015P-RELATED ZINC FINGER PROTEIN 319 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002369.3|UniProtKB=G3QIW1 G3QIW1 THEM6 PTHR12475:SF4 FAMILY NOT NAMED PROTEIN THEM6 GORGO|Ensembl=ENSGGOG00000000762.3|UniProtKB=G3QEQ2 G3QEQ2 CCDC9B PTHR15635:SF10 COILED-COIL DOMAIN CONTAINING PROTEIN 9 COILED-COIL DOMAIN-CONTAINING PROTEIN 9B GORGO|Ensembl=ENSGGOG00000009116.3|UniProtKB=G3SHP1 G3SHP1 PICALM PTHR22951:SF16 CLATHRIN ASSEMBLY PROTEIN PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;SNARE binding#GO:0000149;clathrin binding#GO:0030276;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810 cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;synaptic membrane#GO:0097060;clathrin-coated vesicle#GO:0030136;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000005401.3|UniProtKB=G3QRN1 G3QRN1 AFAP1L1 PTHR14338:SF1 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1-LIKE 1 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000044164.1|UniProtKB=A0A2I2Z163 A0A2I2Z163 PTHR23268:SF126 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000026747.2|UniProtKB=G3S180 G3S180 ST13 PTHR45883:SF6 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN-RELATED Hsp70 protein binding#GO:0030544;protein binding#GO:0005515;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 GORGO|Ensembl=ENSGGOG00000010297.3|UniProtKB=A0A2I2Z421 A0A2I2Z421 PTHR45883:SF6 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN-RELATED Hsp70 protein binding#GO:0030544;protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 GORGO|Ensembl=ENSGGOG00000009388.3|UniProtKB=G3R1T9 G3R1T9 EMD PTHR15171:SF2 EMERIN EMERIN protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 organelle envelope#GO:0031967;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;organelle inner membrane#GO:0019866;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637 GORGO|Ensembl=ENSGGOG00000000651.3|UniProtKB=G3QEE8 G3QEE8 PTHR24418:SF90 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE YES catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Yes#P00476;Parkinson disease#P00049>Src kinase#P01230;CCKR signaling map#P06959>YES1#P07142 GORGO|Ensembl=ENSGGOG00000011354.3|UniProtKB=G3R6V3 G3R6V3 VWA7 PTHR14905:SF7 NG37 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 7 GORGO|Ensembl=ENSGGOG00000025615.2|UniProtKB=G3RYB3 G3RYB3 PTHR22978:SF30 B-CELL TRANSLOCATION GENE PROTEIN BTG1 regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;negative regulation of cellular process#GO:0048523;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000005616.3|UniProtKB=G3QS72 G3QS72 TRMT13 PTHR12998:SF0 TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 GORGO|Ensembl=ENSGGOG00000008164.3|UniProtKB=G3QYP0 G3QYP0 RPL8 PTHR13691:SF16 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016051.3|UniProtKB=G3RIZ2 G3RIZ2 BBS2 PTHR32465:SF0 BARDET-BIEDL SYNDROME 2 PROTEIN BBSOME COMPLEX MEMBER BBS2 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;BBSome#GO:0034464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000012871.3|UniProtKB=A0A2I2YJ10 A0A2I2YJ10 GARNL3 PTHR15711:SF62 RAP GTPASE-ACTIVATING PROTEIN GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1GAP#P00737 GORGO|Ensembl=ENSGGOG00000014972.3|UniProtKB=G3RG67 G3RG67 ZNF320 PTHR24377:SF197 IP01015P-RELATED ZINC FINGER PROTEIN 320 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000039112.1|UniProtKB=A0A2I2YKI9 A0A2I2YKI9 PTHR11875:SF70 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1 LIKE 6 binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515 protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000508.3|UniProtKB=G3QE19 G3QE19 SPTA1 PTHR11915:SF431 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN ALPHA CHAIN, ERYTHROCYTIC 1 actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000001416.3|UniProtKB=G3QGE3 G3QGE3 PSMA1 PTHR11599:SF244 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-1 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000000342.4|UniProtKB=G3QDL6 G3QDL6 LTN1 PTHR12389:SF0 ZINC FINGER PROTEIN 294 E3 UBIQUITIN-PROTEIN LIGASE LISTERIN aminoacyltransferase activity#GO:0016755;ribosomal large subunit binding#GO:0043023;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;translational elongation#GO:0006414;metabolic process#GO:0008152;gene expression#GO:0010467;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;modification-dependent macromolecule catabolic process#GO:0043632;translation#GO:0006412;protein catabolic process#GO:0030163;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;rescue of stalled cytosolic ribosome#GO:0072344;modification-dependent protein catabolic process#GO:0019941 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000002440.3|UniProtKB=G3QJ21 G3QJ21 CANT1 PTHR13023:SF3 APYRASE SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE 1 nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 membrane#GO:0016020;cellular anatomical structure#GO:0110165 nucleotide phosphatase#PC00173;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000012652.3|UniProtKB=A0A2I2ZB89 A0A2I2ZB89 GLRA2 PTHR18945:SF28 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-2 chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic membrane#GO:0097060;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;cell junction#GO:0030054 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000026294.2|UniProtKB=G3S2Q5 G3S2Q5 LOC101141368 PTHR11593:SF11 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003508.3|UniProtKB=G3S193 G3S193 PRAM1 PTHR16830:SF11 SH2 CONTAINING ADAPTOR PRAM-1 RELATED PML-RARA-REGULATED ADAPTER MOLECULE 1 protein localization to membrane#GO:0072657;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;cellular localization#GO:0051641;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;protein localization to cell periphery#GO:1990778;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;localization within membrane#GO:0051668;cell communication#GO:0007154;localization#GO:0051179;macromolecule localization#GO:0033036;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;intracellular protein localization#GO:0008104 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000026288.2|UniProtKB=A0A2I2YC75 A0A2I2YC75 PLPP5 PTHR10165:SF87 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 5 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phospholipid metabolic process#GO:0006644;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000040483.1|UniProtKB=G3RPS7 G3RPS7 LOC101127179 PTHR26453:SF765 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013970.3|UniProtKB=G3RDL5 G3RDL5 MAFK PTHR10129:SF26 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFK transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 GORGO|Ensembl=ENSGGOG00000007193.3|UniProtKB=G3QW91 G3QW91 LOC101150911 PTHR11851:SF116 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036 endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000003027.3|UniProtKB=A0A2I2YPQ7 A0A2I2YPQ7 L2HGDH PTHR43104:SF2 L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cellular process#GO:0009987;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000012580.3|UniProtKB=A0A2I2YID5 A0A2I2YID5 ITSN1 PTHR11216:SF68 EH DOMAIN INTERSECTIN-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;receptor-mediated endocytosis#GO:0006898;endosomal transport#GO:0016197;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;intracellular transport#GO:0046907;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;synaptic vesicle endocytosis#GO:0048488;localization#GO:0051179;cellular localization#GO:0051641 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000005916.3|UniProtKB=G3QSY8 G3QSY8 DUSP4 PTHR10159:SF111 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 4 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 tissue development#GO:0009888;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;endoderm formation#GO:0001706;negative regulation of signal transduction#GO:0009968;embryo development#GO:0009790;regulation of MAPK cascade#GO:0043408;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;endoderm development#GO:0007492;anatomical structure formation involved in morphogenesis#GO:0048646;gastrulation#GO:0007369;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;formation of primary germ layer#GO:0001704;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000008611.3|UniProtKB=G3QZU7 G3QZU7 KCNE5 PTHR15282:SF7 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E REGULATORY BETA SUBUNIT 5 monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel regulator activity#GO:0016247;channel activity#GO:0015267;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;potassium channel regulator activity#GO:0015459;gated channel activity#GO:0022836 regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;cardiac muscle cell action potential involved in contraction#GO:0086002;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;export from cell#GO:0140352;heart process#GO:0003015;regulation of biological process#GO:0050789;action potential#GO:0001508;muscle system process#GO:0003012;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;multicellular organismal process#GO:0032501;potassium ion transport#GO:0006813;blood circulation#GO:0008015;actin filament-based movement#GO:0030048;system process#GO:0003008;heart contraction#GO:0060047;establishment of localization#GO:0051234;cardiac muscle cell contraction#GO:0086003;transport#GO:0006810;muscle contraction#GO:0006936;regulation of system process#GO:0044057;regulation of heart contraction#GO:0008016;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;actin-mediated cell contraction#GO:0070252;monoatomic cation transport#GO:0006812;localization#GO:0051179;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000002940.3|UniProtKB=G3QKC5 G3QKC5 PARP4 PTHR46530:SF1 PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4 PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4 glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 FAS signaling pathway#P00020>PARP#P00600 GORGO|Ensembl=ENSGGOG00000040254.1|UniProtKB=A0A2I2ZRR0 A0A2I2ZRR0 CYSLTR2 PTHR24231:SF48 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000013297.3|UniProtKB=A0A2I2YUT0 A0A2I2YUT0 PRSS3 PTHR24264:SF48 TRYPSIN-RELATED TRYPSIN-3 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000039338.1|UniProtKB=A0A2I2Z4J6 A0A2I2Z4J6 PTHR12765:SF6 RED PROTEIN IK FACTOR CYTOKINE IK IK CYTOKINE nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000005979.3|UniProtKB=G3QT41 G3QT41 TMED1 PTHR22811:SF40 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 1 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000009679.4|UniProtKB=G3R2K2 G3R2K2 NKAIN2 PTHR13084:SF3 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 2 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000010874.3|UniProtKB=A0A2I2ZM83 A0A2I2ZM83 CARD9 PTHR14559:SF3 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 9 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013231.3|UniProtKB=G3RBP6 G3RBP6 MMP19 PTHR10201:SF166 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-19 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000034817.2|UniProtKB=G3SKI6 G3SKI6 LOC101125318 PTHR24028:SF104 CADHERIN-87A PROTOCADHERIN BETA-6 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000014575.3|UniProtKB=G3RFB3 G3RFB3 USP34 PTHR24006:SF827 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34 catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000009769.3|UniProtKB=G3R2U2 G3R2U2 KDM4B PTHR10694:SF30 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4B histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096 regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000003452.3|UniProtKB=G3QLN3 G3QLN3 PTHR24253:SF81 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 9 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;zymogen activation#GO:0031638;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;plasminogen activation#GO:0031639;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000039604.1|UniProtKB=A0A2I2ZA64 A0A2I2ZA64 LOC101149317 PTHR11177:SF405 CHITINASE ACIDIC MAMMALIAN CHITINASE chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000004792.3|UniProtKB=G3QQ38 G3QQ38 R3HCC1L PTHR21678:SF7 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 COILED-COIL DOMAIN-CONTAINING PROTEIN R3HCC1L GORGO|Ensembl=ENSGGOG00000041990.1|UniProtKB=A0A2I2ZUK1 A0A2I2ZUK1 PTHR36527:SF7 OS01G0282866 PROTEIN TUBULIN_FTSZ GTPASE DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000003821.3|UniProtKB=G3QML1 G3QML1 DUS4L PTHR11082:SF31 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(20A_20B) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000022436.2|UniProtKB=G3S3G7 G3S3G7 CCL20 PTHR12015:SF108 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 20 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000008092.3|UniProtKB=G3QYH2 G3QYH2 GLA PTHR11452:SF14 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE A hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 galactosidase#PC00104;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000014314.3|UniProtKB=G3REH4 G3REH4 DSN1 PTHR14778:SF2 KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;outer kinetochore#GO:0000940 GORGO|Ensembl=ENSGGOG00000007889.3|UniProtKB=G3QXZ9 G3QXZ9 NAGA PTHR11452:SF25 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-N-ACETYLGALACTOSAMINIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;galactosidase#PC00104 GORGO|Ensembl=ENSGGOG00000004780.3|UniProtKB=G3QQ44 G3QQ44 FBN3 PTHR24040:SF7 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN FIBRILLIN 2B extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000005438.3|UniProtKB=G3QRR1 G3QRR1 PTHR20835:SF3 E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED SUBFAMILY NOT NAMED protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein phosphatase binding#GO:0019903;phosphatase regulator activity#GO:0019208 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000024077.2|UniProtKB=G3RUL9 G3RUL9 CHCHD4 PTHR21622:SF6 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 MITOCHONDRIAL INTERMEMBRANE SPACE IMPORT AND ASSEMBLY PROTEIN 40 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 transport#GO:0006810;intracellular transport#GO:0046907;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial protein import pathway#GO:7770058;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular localization#GO:0051641;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;mitochondrial transport#GO:0006839 mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000013699.3|UniProtKB=G3RCX7 G3RCX7 DCLRE1C PTHR23240:SF37 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED PROTEIN ARTEMIS nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;5'-3' exonuclease activity#GO:0008409;hydrolase activity#GO:0016787;DNA binding#GO:0003677;exonuclease activity#GO:0004527;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;DNA exonuclease activity#GO:0004529;damaged DNA binding#GO:0003684;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;telomere organization#GO:0032200;cellular response to stress#GO:0033554 DNA repair complex#GO:1990391;nucleus#GO:0005634;nonhomologous end joining complex#GO:0070419;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000015694.3|UniProtKB=G3RI36 G3RI36 JMJD1C PTHR12549:SF6 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN JUMONJI DOMAIN-CONTAINING PROTEIN 1C chromatin DNA binding#GO:0031490;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;histone modifying activity#GO:0140993;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000005506.3|UniProtKB=G3RM78 G3RM78 FAF2 PTHR23322:SF1 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 2 protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003206.4|UniProtKB=G3QL11 G3QL11 DSC3 PTHR24025:SF12 DESMOGLEIN FAMILY MEMBER DESMOCOLLIN-3 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000015054.3|UniProtKB=G3RGF3 G3RGF3 DDX25 PTHR47958:SF33 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX25 ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386 nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;localization#GO:0051179;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000001777.3|UniProtKB=G3QHC4 G3QHC4 GCG PTHR11418:SF0 GLUCAGON PRO-GLUCAGON hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of carbohydrate metabolic process#GO:0006109;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of carbohydrate biosynthetic process#GO:0043255;homeostatic process#GO:0042592;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of protein secretion#GO:0050708;regulation of secretion#GO:0051046;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of establishment of protein localization#GO:0070201;positive regulation of hormone secretion#GO:0046887;regulation of insulin secretion#GO:0050796;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of protein secretion#GO:0050714;regulation of transport#GO:0051049;regulation of localization#GO:0032879;glucose homeostasis#GO:0042593;chemical homeostasis#GO:0048878;response to stimulus#GO:0050896;regulation of protein transport#GO:0051223;signaling#GO:0023052;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;carbohydrate homeostasis#GO:0033500;positive regulation of metabolic process#GO:0009893;regulation of hormone secretion#GO:0046883;positive regulation of signaling#GO:0023056;intracellular glucose homeostasis#GO:0001678;regulation of protein localization#GO:0032880;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 CCKR signaling map#P06959>GCG#G07291;CCKR signaling map#P06959>GCG#G06997 GORGO|Ensembl=ENSGGOG00000011443.3|UniProtKB=A0A2I2YJP6 A0A2I2YJP6 COL5A1 PTHR24023:SF387 COLLAGEN ALPHA COLLAGEN ALPHA-1(V) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000005864.3|UniProtKB=G3QST9 G3QST9 RBM3 PTHR48034:SF12 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA-BINDING PROTEIN 3 ribosomal large subunit binding#GO:0043023;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of protein metabolic process#GO:0051246;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;macromolecule biosynthetic process#GO:0009059;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000017111.3|UniProtKB=G3RLP0 G3RLP0 PGK1 PTHR11406:SF14 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE 1 small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;phosphoglycerate kinase activity#GO:0004618;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotide binding#GO:0000166;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;kinase activity#GO:0016301;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;oxoacid metabolic process#GO:0043436;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;nucleoside diphosphate catabolic process#GO:0009134;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;energy derivation by oxidation of organic compounds#GO:0015980 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 GORGO|Ensembl=ENSGGOG00000043259.1|UniProtKB=A0A2I2ZD93 A0A2I2ZD93 PTHR43920:SF2 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821;monoatomic anion transport#GO:0006820 membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000014412.3|UniProtKB=G3S8R2 G3S8R2 DCP2 PTHR23114:SF17 M7GPPPN-MRNA HYDROLASE M7GPPPN-MRNA HYDROLASE hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080 GORGO|Ensembl=ENSGGOG00000006414.3|UniProtKB=G3SGP9 G3SGP9 ALOX15 PTHR11771:SF33 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX15 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;arachidonate metabolic process#GO:0019369;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid oxidation#GO:0034440;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxygenase#PC00177;oxidoreductase#PC00176 Gonadotropin-releasing hormone receptor pathway#P06664>12-LO#P06815;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 GORGO|Ensembl=ENSGGOG00000014648.3|UniProtKB=G3RFC6 G3RFC6 KLHL8 PTHR24412:SF480 KELCH PROTEIN KELCH-LIKE PROTEIN 8 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000041231.1|UniProtKB=A0A2I2ZQQ3 A0A2I2ZQQ3 PTHR24215:SF3 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 2 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198 striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;cellular developmental process#GO:0048869;developmental process#GO:0032502;tissue development#GO:0009888 intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017;nucleus#GO:0005634;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000011795.3|UniProtKB=G3R800 G3R800 ZNF703 PTHR12522:SF2 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN 703 negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000043770.1|UniProtKB=G3RMN5 G3RMN5 PTHR19971:SF6 SIGNAL-REGULATORY PROTEIN BETA SIGNAL-REGULATORY PROTEIN GAMMA regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of leukocyte activation#GO:0002696;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of cell adhesion#GO:0030155;regulation of T cell activation#GO:0050863;positive regulation of endocytosis#GO:0045807;positive regulation of T cell activation#GO:0050870;regulation of multicellular organismal process#GO:0051239;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of lymphocyte activation#GO:0051251;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;positive regulation of cell adhesion#GO:0045785;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of lymphocyte activation#GO:0051249 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010826.3|UniProtKB=A0A2I2ZHL7 A0A2I2ZHL7 DYNAP PTHR35349:SF7 DYNACTIN-ASSOCIATED PROTEIN DYNACTIN-ASSOCIATED PROTEIN positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000036935.1|UniProtKB=A0A2I2ZWR1 A0A2I2ZWR1 TSNARE1 PTHR19957:SF38 SYNTAXIN T-SNARE DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;vesicle fusion#GO:0006906;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane protein complex#GO:0098796;membrane#GO:0016020 SNARE protein#PC00034 Parkinson disease#P00049>Syntaxin#P01215;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772 GORGO|Ensembl=ENSGGOG00000005337.3|UniProtKB=G3QRH6 G3QRH6 SH3TC1 PTHR22647:SF3 SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003119.3|UniProtKB=G3QKT2 G3QKT2 GJD3 PTHR11984:SF5 CONNEXIN GAP JUNCTION DELTA-3 PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;cell junction#GO:0030054 cell junction protein#PC00070;gap junction#PC00105 GORGO|Ensembl=ENSGGOG00000003411.3|UniProtKB=G3QLJ4 G3QLJ4 GCDH PTHR42807:SF1 GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000014573.3|UniProtKB=G3RF54 G3RF54 LOC101141934 PTHR45819:SF7 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 4-RELATED catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function activator activity#GO:0140677 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000004110.3|UniProtKB=G3QNB9 G3QNB9 QDPR PTHR15104:SF0 DIHYDROPTERIDINE REDUCTASE DIHYDROPTERIDINE REDUCTASE nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000012280.3|UniProtKB=G3R9A1 G3R9A1 RP1 PTHR23005:SF4 RETINITIS PIGMENTOSA 1 PROTEIN OXYGEN-REGULATED PROTEIN 1 tissue homeostasis#GO:0001894;axoneme assembly#GO:0035082;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;retina homeostasis#GO:0001895;microtubule bundle formation#GO:0001578;camera-type eye development#GO:0043010;organelle assembly#GO:0070925;homeostatic process#GO:0042592;visual system development#GO:0150063;multicellular organismal-level homeostasis#GO:0048871;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;sensory organ development#GO:0007423;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;eye development#GO:0001654;neuron development#GO:0048666;cilium organization#GO:0044782;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;nervous system development#GO:0007399;retina development in camera-type eye#GO:0060041;cytoskeleton organization#GO:0007010;anatomical structure homeostasis#GO:0060249;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;sensory system development#GO:0048880;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000041453.1|UniProtKB=A0A2I2Y675 A0A2I2Y675 RBM48 PTHR20957:SF1 RNA-BINDING PROTEIN 48 RNA-BINDING PROTEIN 48 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;catalytic step 2 spliceosome#GO:0071013 GORGO|Ensembl=ENSGGOG00000037283.1|UniProtKB=G3R7L7 G3R7L7 ZXDB PTHR46179:SF21 ZINC FINGER PROTEIN ZINC FINGER X-LINKED PROTEIN ZXDB transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000011215.3|UniProtKB=G3R6H9 G3R6H9 DMC1 PTHR22942:SF30 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER MEIOTIC RECOMBINATION PROTEIN DMC1 HOMOLOG ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 sexual reproduction#GO:0019953;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;homologous recombination#GO:0035825;reproductive process#GO:0022414;DNA damage response#GO:0006974;DNA repair#GO:0006281;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;nucleobase-containing compound metabolic process#GO:0006139;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;protein-containing complex assembly#GO:0065003;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;response to stimulus#GO:0050896;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;double-strand break repair#GO:0006302;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000003019.3|UniProtKB=G3QKK2 G3QKK2 SHANK2 PTHR24135:SF17 SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor complex adaptor activity#GO:0030159;protein binding#GO:0005515;signaling adaptor activity#GO:0035591 multicellular organismal process#GO:0032501;cell junction organization#GO:0034330;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;cognition#GO:0050890;nervous system process#GO:0050877;synapse organization#GO:0050808 postsynapse#GO:0098794;dendritic spine#GO:0043197;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cell projection#GO:0042995;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 Ionotropic glutamate receptor pathway#P00037>PSD95#P00999 GORGO|Ensembl=ENSGGOG00000024751.2|UniProtKB=G3RNM2 G3RNM2 LOX PTHR45817:SF6 LYSYL OXIDASE-LIKE-RELATED PROTEIN-LYSINE 6-OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;extracellular structure organization#GO:0043062;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 oxidase#PC00175;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000005973.3|UniProtKB=G3S585 G3S585 GATAD2A PTHR13455:SF3 TRANSCRIPTIONAL REPRESSOR P66-RELATED TRANSCRIPTIONAL REPRESSOR P66-ALPHA transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000012271.3|UniProtKB=A0A2I2ZM62 A0A2I2ZM62 NRCAM PTHR10075:SF44 BASIGIN RELATED NEURONAL CELL ADHESION MOLECULE cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000002131.3|UniProtKB=G3QI96 G3QI96 SULF2 PTHR43108:SF4 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;carbohydrate derivative metabolic process#GO:1901135;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of cytokine production#GO:0001819;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteoglycan metabolic process#GO:0006029;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of macromolecule metabolic process#GO:0010604;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;extracellular region#GO:0005576 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000042850.1|UniProtKB=G3SJC2 G3SJC2 IRX1 PTHR11211:SF13 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;cell development#GO:0048468;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000013754.3|UniProtKB=G3RD24 G3RD24 ATP6V0D2 PTHR11028:SF2 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324 biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular transport#GO:0046907;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular localization#GO:0051641;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885 cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;ATPase dependent transmembrane transport complex#GO:0098533;early endosome#GO:0005769;ATPase complex#GO:1904949;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;lytic vacuole#GO:0000323;proton-transporting two-sector ATPase complex#GO:0016469;intracellular membrane-bounded organelle#GO:0043231;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774 ATP synthase#PC00002 GORGO|Gene=TOPAZ1|UniProtKB=G3S077 G3S077 TOPAZ1 PTHR35671:SF1 PROTEIN TOPAZ1 PROTEIN TOPAZ1 spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;cell division#GO:0051301;cellular process#GO:0009987;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproductive process#GO:0022414 GORGO|Ensembl=ENSGGOG00000025465.3|UniProtKB=A0A2I2Y8W9 A0A2I2Y8W9 EDIL3 PTHR24543:SF333 MULTICOPPER OXIDASE-RELATED EGF-LIKE REPEAT AND DISCOIDIN I-LIKE DOMAIN-CONTAINING PROTEIN 3 regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000008834.2|UniProtKB=G3R0E9 G3R0E9 LOC101149901 PTHR24242:SF369 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000007478.3|UniProtKB=G3QWZ1 G3QWZ1 ZNF280B PTHR24388:SF110 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 280B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000014489.3|UniProtKB=G3REY1 G3REY1 NPR3 PTHR44755:SF1 NATRIURETIC PEPTIDE RECEPTOR 3-RELATED ATRIAL NATRIURETIC PEPTIDE RECEPTOR 3 signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;binding#GO:0005488;hormone binding#GO:0042562 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007549.3|UniProtKB=G3QX52 G3QX52 BLOC1S4 PTHR16230:SF4 CAPPUCCINO BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 4 hemostasis#GO:0007599;cellular component organization#GO:0016043;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;cell activation#GO:0001775;pigmentation#GO:0043473;cell adhesion#GO:0007155;wound healing#GO:0042060;regulation of biological quality#GO:0065008;cellular process#GO:0009987;coagulation#GO:0050817;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;response to wounding#GO:0009611;organelle organization#GO:0006996;homotypic cell-cell adhesion#GO:0034109;cellular pigmentation#GO:0033059;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;melanosome organization#GO:0032438;platelet aggregation#GO:0070527;blood coagulation#GO:0007596;vesicle organization#GO:0016050;platelet activation#GO:0030168;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;BLOC-1 complex#GO:0031083;intracellular protein-containing complex#GO:0140535 GORGO|Ensembl=ENSGGOG00000010905.3|UniProtKB=A0A2I2YCA3 A0A2I2YCA3 ENTR1 PTHR31259:SF6 ENDOSOME-ASSOCIATED TRAFFICKING REGULATOR 1 ENDOSOME-ASSOCIATED-TRAFFICKING REGULATOR 1 regulation of localization#GO:0032879;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cell projection assembly#GO:0060491;regulation of protein localization#GO:0032880;positive regulation of organelle organization#GO:0010638;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;midbody#GO:0030496;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;endosome#GO:0005768;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;recycling endosome#GO:0055037;centrosome#GO:0005813;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856 GORGO|Ensembl=ENSGGOG00000012329.3|UniProtKB=G3S4H3 G3S4H3 CDR2L PTHR19232:SF10 CENTROCORTIN FAMILY MEMBER CEREBELLAR DEGENERATION-RELATED PROTEIN 2-LIKE GORGO|Ensembl=ENSGGOG00000009396.3|UniProtKB=G3R1U7 G3R1U7 CEP295 PTHR21553:SF25 ALMS1-RELATED CENTROSOMAL PROTEIN OF 295 KDA regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of microtubule-based process#GO:0032886 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016913.3|UniProtKB=G3RL64 G3RL64 TMUB1 PTHR14557:SF3 PROTEIN C7ORF21 TRANSMEMBRANE AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN 1 response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 GORGO|Ensembl=ENSGGOG00000011649.3|UniProtKB=G3R7M3 G3R7M3 CLIC3 PTHR43920:SF3 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL PROTEIN 3 channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000036585.1|UniProtKB=A0A2I2YM99 A0A2I2YM99 CSNK2A2IP PTHR35825:SF2 CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN GORGO|Ensembl=ENSGGOG00000042317.1|UniProtKB=A0A2I2ZS26 A0A2I2ZS26 PTHR48112:SF11 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B1 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 p53 pathway#P00059>HMG1#P04619 GORGO|Ensembl=ENSGGOG00000005496.3|UniProtKB=G3QRW7 G3QRW7 ZC3H13 PTHR13585:SF31 CHASCON, ISOFORM D-RELATED ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;transferase complex#GO:1990234;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000016315.3|UniProtKB=G3RJL8 G3RJL8 CDO1 PTHR12918:SF1 CYSTEINE DIOXYGENASE CYSTEINE DIOXYGENASE TYPE 1 catalytic activity#GO:0003824;ferrous iron binding#GO:0008198;oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;cation binding#GO:0043169;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;sulfur compound catabolic process#GO:0044273 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000009283.3|UniProtKB=A0A2I2Z302 A0A2I2Z302 CAST PTHR10077:SF0 CALPASTATIN CALPASTATIN molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000015070.3|UniProtKB=G3RGG4 G3RGG4 RAB3GAP1 PTHR21422:SF18 RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;system development#GO:0048731;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;developmental process#GO:0032502;regulation of cellular component biogenesis#GO:0044087;positive regulation of macroautophagy#GO:0016239;central nervous system development#GO:0007417;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;regulation of autophagosome assembly#GO:2000785;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;positive regulation of autophagy#GO:0010508;regulation of macroautophagy#GO:0016241;animal organ development#GO:0048513;multicellular organism development#GO:0007275 GTPase-activating protein#PC00257;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000013953.4|UniProtKB=A0A2I2ZUB7 A0A2I2ZUB7 PCYT2 PTHR45780:SF2 ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000014919.3|UniProtKB=G3RG24 G3RG24 SLC22A10 PTHR24064:SF278 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 10 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000022369.2|UniProtKB=G3SI15 G3SI15 SEC23B PTHR11141:SF10 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23B enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996 COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506 vesicle coat protein#PC00235;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000043426.1|UniProtKB=G3SK32 G3SK32 PTHR12801:SF22 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED EXONUCLEASE GOR-RELATED hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 exoribonuclease#PC00099;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004931.3|UniProtKB=A0A2I2ZUQ6 A0A2I2ZUQ6 MED8 PTHR13074:SF9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000016261.3|UniProtKB=G3RJH0 G3RJH0 TYRP1 PTHR11474:SF3 TYROSINASE FAMILY MEMBER 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID OXIDASE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cell differentiation#GO:0030154;cellular pigmentation#GO:0033059;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;developmental pigmentation#GO:0048066;melanocyte differentiation#GO:0030318;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;melanosome organization#GO:0032438;developmental process#GO:0032502;pigmentation#GO:0043473 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;melanosome#GO:0042470;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000024975.2|UniProtKB=G3SF23 G3SF23 OR51T1 PTHR26450:SF6 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51T1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014973.3|UniProtKB=G3SDF2 G3SDF2 ARHGEF11 PTHR45872:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 11 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000004997.3|UniProtKB=G3QQN0 G3QQN0 WDR5 PTHR22847:SF560 WD40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 transcription by RNA polymerase II#GO:0006366;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;DNA-templated transcription initiation#GO:0006352 chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;NSL complex#GO:0044545;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000037299.1|UniProtKB=A0A2I2YLI2 A0A2I2YLI2 PTHR12345:SF23 SYNTENIN RELATED PDZ DOMAIN-CONTAINING PROTEIN carbohydrate derivative binding#GO:0097367;binding#GO:0005488;protein binding#GO:0005515 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of response to stimulus#GO:0048583 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000008995.3|UniProtKB=G3S5A5 G3S5A5 PCDHB5 PTHR24028:SF90 CADHERIN-87A PROTOCADHERIN BETA-5 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 GORGO|Ensembl=ENSGGOG00000001593.3|UniProtKB=G3QGV5 G3QGV5 CCDC115 PTHR31996:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 115 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA22 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;intracellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725 membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting two-sector ATPase complex#GO:0016469;endoplasmic reticulum#GO:0005783;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000009520.3|UniProtKB=G3R266 G3R266 SIN3B PTHR12346:SF1 SIN3B-RELATED PAIRED AMPHIPATHIC HELIX PROTEIN SIN3B transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771 GORGO|Ensembl=ENSGGOG00000022507.2|UniProtKB=A0A2I2Y9M3 A0A2I2Y9M3 PPIH PTHR11071:SF443 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000011530.3|UniProtKB=G3R7B3 G3R7B3 TNFSF13 PTHR15151:SF12 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of DNA recombination#GO:0000018;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of leukocyte activation#GO:0002694;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of lymphocyte activation#GO:0051249;positive regulation of leukocyte activation#GO:0002696;positive regulation of immune system process#GO:0002684;regulation of B cell activation#GO:0050864;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of biosynthetic process#GO:0009891;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of lymphocyte activation#GO:0051251;regulation of immune effector process#GO:0002697;positive regulation of DNA metabolic process#GO:0051054;regulation of leukocyte mediated immunity#GO:0002703;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of developmental process#GO:0050793;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of developmental process#GO:0051094;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of cell activation#GO:0050867 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000015053.3|UniProtKB=G3RGE5 G3RGE5 DNAJC12 PTHR44500:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000013473.3|UniProtKB=G3RCC2 G3RCC2 RANGAP1 PTHR24113:SF12 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 molecular function activator activity#GO:0140677;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;enzyme binding#GO:0019899;binding#GO:0005488;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 intracellular transport#GO:0046907;transport#GO:0006810;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;perinuclear region of cytoplasm#GO:0048471;cytosol#GO:0005829;nucleus#GO:0005634 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000043963.1|UniProtKB=A0A2I2YQV8 A0A2I2YQV8 LOC101142266 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000028250.2|UniProtKB=G3RT30 G3RT30 PTHR11193:SF8 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613 U2 snRNP#GO:0005686;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000014758.3|UniProtKB=G3RFN1 G3RFN1 PTHR45888:SF7 HL01030P-RELATED ZINC FINGER PROTEIN UBI-D4 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005694.3|UniProtKB=G3QSE2 G3QSE2 ZSCAN20 PTHR23226:SF440 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 20 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000000221.3|UniProtKB=G3QDA7 G3QDA7 ELOVL6 PTHR11157:SF125 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 6 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000038758.1|UniProtKB=A0A2I2Z557 A0A2I2Z557 NRXN1 PTHR15036:SF51 PIKACHURIN-LIKE PROTEIN NEUREXIN-1 signaling receptor binding#GO:0005102;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023 macromolecule localization#GO:0033036;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;developmental process#GO:0032502;intracellular protein localization#GO:0008104;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;postsynapse organization#GO:0099173;cognition#GO:0050890;protein localization to cell junction#GO:1902414;organelle assembly#GO:0070925;synapse organization#GO:0050808;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;postsynaptic specialization organization#GO:0099084;system development#GO:0048731;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;postsynaptic density assembly#GO:0097107;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;response to stimulus#GO:0050896;excitatory synapse assembly#GO:1904861;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;nervous system process#GO:0050877;postsynaptic density organization#GO:0097106 plasma membrane region#GO:0098590;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;membrane#GO:0016020;presynaptic active zone membrane#GO:0048787;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;presynaptic active zone#GO:0048786;synaptic membrane#GO:0097060 cell adhesion molecule#PC00069 GORGO|Gene=TAS2R8|UniProtKB=Q646A3 Q646A3 TAS2R8 PTHR11394:SF31 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 8 transmembrane signaling receptor activity#GO:0004888;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005727.3|UniProtKB=G3QSH5 G3QSH5 JAK3 PTHR45807:SF3 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK3 transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;cytokine receptor binding#GO:0005126;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672 immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;developmental process#GO:0032502;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;response to external stimulus#GO:0009605;defense response#GO:0006952;cellular developmental process#GO:0048869;innate immune response#GO:0045087;interleukin-2-mediated signaling pathway#GO:0038110;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to type II interferon#GO:0034341;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to hormone#GO:0009725;interleukin-9-mediated signaling pathway#GO:0038113;interleukin-15-mediated signaling pathway#GO:0035723;cell surface receptor signaling pathway via STAT#GO:0097696;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;interleukin-7-mediated signaling pathway#GO:0038111;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;cellular response to hormone stimulus#GO:0032870;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to peptide#GO:1901652 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 non-receptor tyrosine protein kinase#PC00168 Interleukin signaling pathway#P00036>Jak#P00978;JAK/STAT signaling pathway#P00038>Jak#P01034;PDGF signaling pathway#P00047>Jak#P01155 GORGO|Ensembl=ENSGGOG00000011436.3|UniProtKB=G3R725 G3R725 RBKS PTHR10584:SF166 SUGAR KINASE RIBOKINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000006867.3|UniProtKB=G3QVF8 G3QVF8 PTHR11252:SF9 POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;RNA 3'-end processing#GO:0031123;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000015347.3|UniProtKB=G3RH55 G3RH55 PTHR24073:SF528 DRAB5-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 22 HOMOLOG GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000023722.2|UniProtKB=A0A2I2Z2I2 A0A2I2Z2I2 PTHR13342:SF3 RAGULATOR COMPLEX PROTEIN LAMTOR5 RAGULATOR COMPLEX PROTEIN LAMTOR5 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of TORC1 signaling#GO:1904263;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;membrane protein complex#GO:0098796 GORGO|Ensembl=ENSGGOG00000002743.3|UniProtKB=G3QJU9 G3QJU9 PPM1J PTHR13832:SF305 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1J phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000010474.3|UniProtKB=G3R4L3 G3R4L3 AQP4 PTHR19139:SF34 AQUAPORIN TRANSPORTER AQUAPORIN-4 channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372 transport#GO:0006810;localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;fluid transport#GO:0042044 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003609.3|UniProtKB=A0A2I2YF97 A0A2I2YF97 DNAH17 PTHR45703:SF4 DYNEIN HEAVY CHAIN DYNEIN AXONEMAL HEAVY CHAIN 17 microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000036689.1|UniProtKB=A0A2I2Z5K9 A0A2I2Z5K9 RHOBTB2 PTHR24072:SF137 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 establishment or maintenance of cell polarity#GO:0007163;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;actin filament organization#GO:0007015;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000007592.3|UniProtKB=G3QX89 G3QX89 FGF6 PTHR11486:SF25 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 6 receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to fibroblast growth factor#GO:0071774;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000016909.3|UniProtKB=G3RL61 G3RL61 ZDHHC2 PTHR22883:SF207 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC2 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096 system development#GO:0048731;cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;localization within membrane#GO:0051668;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;synapse assembly#GO:0007416;protein targeting#GO:0006605;cell junction organization#GO:0034330;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;establishment of localization#GO:0051234;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;protein targeting to membrane#GO:0006612;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006181.3|UniProtKB=G3QTM8 G3QTM8 CRAMP1 PTHR21677:SF1 CRAMPED PROTEIN PROTEIN CRAMPED-LIKE binding#GO:0005488;chromatin binding#GO:0003682 developmental process#GO:0032502;pattern specification process#GO:0007389;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000038010.1|UniProtKB=A0A2I2ZE07 A0A2I2ZE07 PTHR13309:SF2 NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1 SUBFAMILY NOT NAMED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-RNA complex assembly#GO:0022618;protein-containing complex organization#GO:0043933 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004812.3|UniProtKB=G3QQ55 G3QQ55 SLC2A4RG PTHR13006:SF8 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 SLC2A4 REGULATOR transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000008692.3|UniProtKB=A0A2I2YL61 A0A2I2YL61 DNM3 PTHR11566:SF54 DYNAMIN DYNAMIN-3 ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;protein binding#GO:0005515;GTPase activity#GO:0003924;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;synaptic vesicle transport#GO:0048489;organelle organization#GO:0006996;cellular localization#GO:0051641;localization#GO:0051179;organelle localization#GO:0051640;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488 synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054 membrane traffic protein#PC00150 GORGO|Gene=HBG1|UniProtKB=P62741 P62741 HBG1 PTHR11442:SF52 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT GAMMA-1 protein binding#GO:0005515;tetrapyrrole binding#GO:0046906;molecular carrier activity#GO:0140104;binding#GO:0005488;heme binding#GO:0020037 homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;localization#GO:0051179;cell development#GO:0048468;homeostatic process#GO:0042592;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;cellular process#GO:0009987;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transfer/carrier protein#PC00219;globin#PC00107 GORGO|Ensembl=ENSGGOG00000011783.3|UniProtKB=G3R7Z4 G3R7Z4 DGKE PTHR11255:SF54 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE EPSILON catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 primary metabolic process#GO:0044238;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;membrane#GO:0016020 kinase#PC00137;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000013349.3|UniProtKB=G3RC03 G3RC03 CDK7 PTHR24056:SF375 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 7 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cell cycle#GO:0051726;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of cellular process#GO:0050794;DNA-templated transcription initiation#GO:0006352;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transcription factor TFIIH holo complex#GO:0005675;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription regulator complex#GO:0005667;transferase complex#GO:1990234 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000022402.2|UniProtKB=G3RMZ0 G3RMZ0 GSKIP PTHR12490:SF4 GSK3B-INTERACTING PROTEIN GSK3B-INTERACTING PROTEIN binding#GO:0005488;protein kinase A binding#GO:0051018;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000008917.3|UniProtKB=G3R0M6 G3R0M6 SUSD3 PTHR46879:SF1 SUSHI DOMAIN-CONTAINING PROTEIN 3 SUSHI DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000040111.1|UniProtKB=A0A2I2Y8W0 A0A2I2Y8W0 ZNF268 PTHR23232:SF161 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 350 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002981.3|UniProtKB=G3QKF6 G3QKF6 HAPLN4 PTHR22804:SF11 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 4 anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 cell junction#GO:0030054;extracellular region#GO:0005576;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cell periphery#GO:0071944 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 GORGO|Ensembl=ENSGGOG00000013827.3|UniProtKB=G3RD85 G3RD85 PLA2G2F PTHR11716:SF8 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP IIF SECRETORY PHOSPHOLIPASE A2 A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;lipid binding#GO:0008289;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;cation binding#GO:0043169;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094 primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of T cell proliferation#GO:0042129;phosphatidylglycerol metabolic process#GO:0046471;phospholipid metabolic process#GO:0006644;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;negative regulation of cell population proliferation#GO:0008285;organophosphate metabolic process#GO:0019637;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;negative regulation of cell adhesion#GO:0007162;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;lipid metabolic process#GO:0006629;negative regulation of cell activation#GO:0050866;phosphorus metabolic process#GO:0006793;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;regulation of lymphocyte activation#GO:0051249;regulation of mononuclear cell proliferation#GO:0032944;cellular process#GO:0009987;regulation of T cell activation#GO:0050863;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;negative regulation of lymphocyte activation#GO:0051250;metabolic process#GO:0008152;regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000009446.3|UniProtKB=G3R1Z5 G3R1Z5 BTBD1 PTHR24410:SF18 HL07962P-RELATED BTB DOMAIN CONTAINING 1 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000013210.3|UniProtKB=G3RBM6 G3RBM6 OLR1 PTHR47298:SF1 OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 low-density lipoprotein particle receptor activity#GO:0005041;cargo receptor activity#GO:0038024 cell adhesion#GO:0007155;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;leukocyte cell-cell adhesion#GO:0007159;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell-cell adhesion#GO:0098609;lipoprotein metabolic process#GO:0042157 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000037127.1|UniProtKB=A0A2I2ZJU0 A0A2I2ZJU0 ZNF80 PTHR23226:SF203 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 80 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005208.3|UniProtKB=G3QR69 G3QR69 WDR77 PTHR46853:SF3 METHYLOSOME PROTEIN 50 METHYLOSOME PROTEIN WDR77 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000005997.3|UniProtKB=A0A2I2YAI6 A0A2I2YAI6 ATP6V1G2 PTHR12713:SF33 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G cellular component organization#GO:0016043;homeostatic process#GO:0042592;monoatomic ion transport#GO:0006811;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;vesicle-mediated transport#GO:0016192;developmental maturation#GO:0021700;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;developmental process#GO:0032502;vesicle organization#GO:0016050;cellular homeostasis#GO:0019725;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188 vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;cation-transporting ATPase complex#GO:0090533;synaptic vesicle#GO:0008021;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory vesicle#GO:0099503;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;proton-transporting two-sector ATPase complex#GO:0016469;cell junction#GO:0030054;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;ATPase complex#GO:1904949;ATPase dependent transmembrane transport complex#GO:0098533 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000015958.3|UniProtKB=G3SC78 G3SC78 FLOT2 PTHR13806:SF46 FLOTILLIN-RELATED FLOTILLIN-2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000016516.3|UniProtKB=G3RK55 G3RK55 PRPF31 PTHR13904:SF0 PRE-MRNA SPLICING FACTOR PRP31 U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000004766.3|UniProtKB=G3QQ12 G3QQ12 PTHR26450:SF454 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006638.3|UniProtKB=G3QUT8 G3QUT8 CD5 PTHR47309:SF1 T-CELL SURFACE GLYCOPROTEIN CD5 T-CELL SURFACE GLYCOPROTEIN CD5 positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of T cell activation#GO:0050863;regulation of cell adhesion#GO:0030155;positive regulation of T cell activation#GO:0050870;regulation of multicellular organismal process#GO:0051239;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of leukocyte activation#GO:0002696;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;positive regulation of cell adhesion#GO:0045785;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;positive regulation of lymphocyte activation#GO:0051251 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000007660.3|UniProtKB=G3QXF0 G3QXF0 NUTM1 PTHR22879:SF13 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 1 GORGO|Ensembl=ENSGGOG00000008289.3|UniProtKB=G3SG16 G3SG16 PTHR16200:SF3 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ZNRF3 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;signaling receptor binding#GO:0005102;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of cell communication#GO:0010648;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002449.3|UniProtKB=G3S4Y6 G3S4Y6 SGSM2 PTHR22957:SF194 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000004292.3|UniProtKB=G3QNT5 G3QNT5 LPCAT3 PTHR13906:SF14 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 lipid modification#GO:0030258;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;phosphatidylcholine biosynthetic process#GO:0006656;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 membrane#GO:0016020;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000042018.1|UniProtKB=A0A2I2ZEP4 A0A2I2ZEP4 PTHR15268:SF18 THRAP3/BCLAF1 BCLAF1 DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000007589.4|UniProtKB=G3QX88 G3QX88 CAMK4 PTHR24347:SF391 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000027206.2|UniProtKB=A0A2I2YS82 A0A2I2YS82 PTHR15082:SF2 NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3 mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000006756.3|UniProtKB=A0A2I2Y7E4 A0A2I2Y7E4 ACADVL PTHR43884:SF11 ACYL-COA DEHYDROGENASE VERY LONG-CHAIN ACYL-COA DEHYDROGENASE, MITOCHONDRIAL lipid binding#GO:0008289;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000003509.4|UniProtKB=G3QLT3 G3QLT3 MXRA5 PTHR45842:SF4 SYNAPTIC ADHESION-LIKE MOLECULE SALM MATRIX-REMODELING-ASSOCIATED PROTEIN 5 response to endogenous stimulus#GO:0009719;response to transforming growth factor beta#GO:0071559;response to growth factor#GO:0070848;response to stimulus#GO:0050896 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000026231.2|UniProtKB=G3SIC6 G3SIC6 PTHR10075:SF147 BASIGIN RELATED PROTOGENIN cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000014796.3|UniProtKB=A0A2I2ZE71 A0A2I2ZE71 RBBP5 PTHR44040:SF1 RETINOBLASTOMA-BINDING PROTEIN 5 RETINOBLASTOMA-BINDING PROTEIN 5 Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 GORGO|Ensembl=ENSGGOG00000038403.1|UniProtKB=A0A2I2YHC0 A0A2I2YHC0 LOC109025121 PTHR19256:SF71 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000013190.3|UniProtKB=G3QLK5 G3QLK5 PCDHB16 PTHR24028:SF54 CADHERIN-87A PROTOCADHERIN BETA-10 cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000015979.3|UniProtKB=G3RIS3 G3RIS3 DTX3L PTHR12622:SF41 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX3L ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001660.3|UniProtKB=G3QH17 G3QH17 RPL27A PTHR11721:SF27 60S RIBOSOMAL PROTEIN L27A LARGE RIBOSOMAL SUBUNIT PROTEIN UL15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000002396.3|UniProtKB=G3QIY7 G3QIY7 SYTL5 PTHR45716:SF6 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 5 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000001815.3|UniProtKB=G3QHG2 G3QHG2 TLK2 PTHR22974:SF20 MIXED LINEAGE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TOUSLED-LIKE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;chromosome segregation#GO:0007059 nucleus#GO:0005634;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008303.3|UniProtKB=G3QZ17 G3QZ17 KDELR3 PTHR10585:SF33 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR 3 signal sequence receptor activity#GO:0005048 cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365;cellular localization#GO:0051641 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000001137.3|UniProtKB=G3QFP5 G3QFP5 RNF130 PTHR22765:SF40 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF130 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cell death#GO:0008219;cellular process#GO:0009987;programmed cell death#GO:0012501 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012384.3|UniProtKB=G3R9K6 G3R9K6 HKDC1 PTHR19443:SF28 HEXOKINASE HEXOKINASE HKDC1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;hexokinase activity#GO:0004396;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;chemical homeostasis#GO:0048878;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;intracellular glucose homeostasis#GO:0001678;oxoacid metabolic process#GO:0043436;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;intracellular chemical homeostasis#GO:0055082;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;homeostatic process#GO:0042592;glucose 6-phosphate metabolic process#GO:0051156;catabolic process#GO:0009056;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside diphosphate catabolic process#GO:0009137;glucose homeostasis#GO:0042593;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyruvate metabolic process#GO:0006090;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787;cellular homeostasis#GO:0019725;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;cytoplasmic side of membrane#GO:0098562;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966;Pentose phosphate pathway#P02762>Hexokinase#P03079 GORGO|Ensembl=ENSGGOG00000002748.3|UniProtKB=A0A2I2ZYX7 A0A2I2ZYX7 DHX33 PTHR18934:SF118 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX33 RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase I#GO:0006356;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase I#GO:0045943;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 RNA metabolism protein#PC00031;RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000006557.3|UniProtKB=G3RX73 G3RX73 NFIC PTHR11492:SF2 NUCLEAR FACTOR I NUCLEAR FACTOR 1 C-TYPE RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000027559.2|UniProtKB=G3S108 G3S108 KCNA1 PTHR11537:SF24 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 1 potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843 metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 transmembrane transporter complex#GO:1902495;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell body#GO:0044297;membrane protein complex#GO:0098796;transporter complex#GO:1990351;cell junction#GO:0030054;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;main axon#GO:0044304;neuron projection#GO:0043005;membrane#GO:0016020 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000004192.3|UniProtKB=G3QNK1 G3QNK1 EPB41L4B PTHR23280:SF18 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4B actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component organization#GO:0016043;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell adhesion#GO:0045785;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032 cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000003945.3|UniProtKB=A0A2I2Y9C8 A0A2I2Y9C8 TTC39C PTHR31859:SF24 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39C embryonic organ development#GO:0048568;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;ear development#GO:0043583;cilium organization#GO:0044782;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;sensory organ development#GO:0007423;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;inner ear morphogenesis#GO:0042472;inner ear development#GO:0048839;plasma membrane bounded cell projection organization#GO:0120036;embryo development#GO:0009790;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501 GORGO|Ensembl=ENSGGOG00000016687.3|UniProtKB=A0A2I2ZK19 A0A2I2ZK19 SRCAP PTHR45685:SF4 HELICASE SRCAP-RELATED CHROMATIN REMODELING PROTEIN SRCAP ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;catalytic complex#GO:1902494;ATPase complex#GO:1904949;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000025475.2|UniProtKB=G3S7I0 G3S7I0 FABP7 PTHR11955:SF57 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, BRAIN organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;lipid binding#GO:0008289;fatty acid binding#GO:0005504 lipid transport#GO:0006869;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000003048.3|UniProtKB=G3QKL9 G3QKL9 SOST PTHR14903:SF4 SCLEROSTIN-RELATED SCLEROSTIN binding#GO:0005488;cytokine binding#GO:0019955;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;ossification#GO:0001503;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of BMP signaling pathway#GO:0030510;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of BMP signaling pathway#GO:0030514 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000010642.3|UniProtKB=G3R512 G3R512 LOC101141122 PTHR24250:SF53 CHYMOTRYPSIN-RELATED CHYMOTRYPSINOGEN B2 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001205.3|UniProtKB=G3QFV6 G3QFV6 TENT5A PTHR12974:SF25 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5A catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;positive regulation of biosynthetic process#GO:0009891;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889 GORGO|Ensembl=ENSGGOG00000025402.2|UniProtKB=A0A2I2ZJT0 A0A2I2ZJT0 PTHR16284:SF13 PROTEIN CDV3 HOMOLOG PROTEIN CDV3 HOMOLOG cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040705.1|UniProtKB=A0A2I2ZYE5 A0A2I2ZYE5 PTHR10480:SF2 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG C protein binding#GO:0005515;syntaxin binding#GO:0019905;binding#GO:0005488;calmodulin binding#GO:0005516;SNARE binding#GO:0000149 transport#GO:0006810;synaptic vesicle cycle#GO:0099504;calcium-ion regulated exocytosis#GO:0017156;establishment of localization#GO:0051234;vesicle localization#GO:0051648;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic transmission, glutamatergic#GO:0035249;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656 synaptic membrane#GO:0097060;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular vesicle#GO:0097708;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;axon terminus#GO:0043679;organelle membrane#GO:0031090;neuromuscular junction#GO:0031594;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;distal axon#GO:0150034;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306 Synaptic vesicle trafficking#P05734>Munc13#P05773 GORGO|Ensembl=ENSGGOG00000000053.3|UniProtKB=G3QCV4 G3QCV4 PTHR46603:SF1 ABSCISSION/NOCUT CHECKPOINT REGULATOR ABSCISSION_NOCUT CHECKPOINT REGULATOR phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794 midbody#GO:0030496;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;cleavage furrow#GO:0032154;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000000338.3|UniProtKB=G3QDL0 G3QDL0 PPP2CA PTHR45619:SF81 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT ALPHA ISOFORM phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 p53 pathway feedback loops 2#P04398>PP2A-C#P04659;Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;p53 pathway#P00059>PP2A#P04630;EGF receptor signaling pathway#P00018>PP2A#P00547 GORGO|Ensembl=ENSGGOG00000003556.3|UniProtKB=G3QLX0 G3QLX0 LSM10 PTHR21196:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 GORGO|Gene=APOBEC3C|UniProtKB=Q694B5 Q694B5 APOBEC3C PTHR13857:SF46 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3C nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;base conversion or substitution editing#GO:0016553;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;macromolecule modification#GO:0043412;response to virus#GO:0009615;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cytidine to uridine editing#GO:0016554;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to external biotic stimulus#GO:0043207 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000000907.3|UniProtKB=G3S178 G3S178 CACNA1F PTHR45628:SF2 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1F monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509 voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241 Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082 GORGO|Ensembl=ENSGGOG00000013903.3|UniProtKB=G3RDF5 G3RDF5 PTHR46032:SF6 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000000890.3|UniProtKB=G3QF18 G3QF18 XPO4 PTHR12596:SF1 EXPORTIN 4,7-RELATED EXPORTIN-4 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000027402.2|UniProtKB=G3SJM3 G3SJM3 CNOT2 PTHR23326:SF35 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2 regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 CCR4-NOT complex#GO:0030014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000028199.2|UniProtKB=G3RJF7 G3RJF7 PTHR42796:SF3 FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED OXALOACETATE TAUTOMERASE FAHD2A, MITOCHONDRIAL-RELATED hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000002253.3|UniProtKB=G3QIK6 G3QIK6 AADAC PTHR23024:SF222 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;lipase activity#GO:0016298;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;neutral lipid catabolic process#GO:0046461;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;acylglycerol metabolic process#GO:0006639;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 deacetylase#PC00087 GORGO|Ensembl=ENSGGOG00000011338.3|UniProtKB=A0A2I2YSF4 A0A2I2YSF4 MSH5 PTHR11361:SF20 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER MUTS PROTEIN HOMOLOG 5 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component assembly#GO:0022607;homologous chromosome pairing at meiosis#GO:0007129;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;homologous recombination#GO:0035825;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000037061.1|UniProtKB=A0A2I2ZDR7 A0A2I2ZDR7 PTHR23210:SF23 ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000011842.3|UniProtKB=G3R851 G3R851 FARS2 PTHR11538:SF41 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000000950.3|UniProtKB=G3QF70 G3QF70 PRR14 PTHR14522:SF2 EMO2-RELATED PROLINE-RICH PROTEIN 14 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000011367.3|UniProtKB=G3S4Z4 G3S4Z4 AHR PTHR10649:SF9 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR sequence-specific double-stranded DNA binding#GO:1990837;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000008523.3|UniProtKB=G3QZM1 G3QZM1 CHIA PTHR11177:SF188 CHITINASE ACIDIC MAMMALIAN CHITINASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000024839.2|UniProtKB=A0A2I2Z0E8 A0A2I2Z0E8 PTHR11732:SF437 ALDO/KETO REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000001123.3|UniProtKB=G3QFN1 G3QFN1 KATNA1 PTHR23074:SF71 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A1 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000040718.1|UniProtKB=A0A2I2YEG8 A0A2I2YEG8 PTHR23428:SF298 HISTONE H2B HISTONE H2B TYPE 2-C-RELATED defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000016784.3|UniProtKB=G3RKU5 G3RKU5 SRXN1 PTHR21348:SF4 FAMILY NOT NAMED SULFIREDOXIN-1 antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491 cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;response to stimulus#GO:0050896 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000011743.4|UniProtKB=G3R7X6 G3R7X6 PRRC2C PTHR14038:SF6 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2C binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001054.3|UniProtKB=G3SF92 G3SF92 PSMD11 PTHR10678:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 GORGO|Ensembl=ENSGGOG00000015554.3|UniProtKB=A0A2I2Z7B3 A0A2I2Z7B3 SOD1 PTHR10003:SF112 SUPEROXIDE DISMUTASE CU-ZN -RELATED SUPEROXIDE DISMUTASE [CU-ZN] oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;copper ion binding#GO:0005507;antioxidant activity#GO:0016209;metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914 response to reactive oxygen species#GO:0000302;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular process#GO:0009987;cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;cytosol#GO:0005829;nucleus#GO:0005634;mitochondrion#GO:0005739;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000004729.3|UniProtKB=G3S223 G3S223 MTG1 PTHR45782:SF4 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;mitochondrial large ribosomal subunit assembly#GO:1902775;protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;cellular component assembly#GO:0022607;cellular process#GO:0009987;ribosomal large subunit assembly#GO:0000027;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000022725.2|UniProtKB=A0A885 A0A885 PIP PTHR15096:SF5 PROLACTIN-INDUCIBLE PROTEIN/SEMINAL VESICLE ANTIGEN PROLACTIN-INDUCIBLE PROTEIN catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000012193.3|UniProtKB=G3R923 G3R923 VEGFB PTHR12025:SF12 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR B molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 positive regulation of chemotaxis#GO:0050921;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to growth factor#GO:0070848;regulation of leukocyte migration#GO:0002685;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;positive regulation of locomotion#GO:0040017;response to hypoxia#GO:0001666;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;tube development#GO:0035295;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;response to stimulus#GO:0050896;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;response to abiotic stimulus#GO:0009628;vascular endothelial growth factor receptor signaling pathway#GO:0048010;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of response to external stimulus#GO:0032103;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cell surface receptor signaling pathway#GO:0007166;regulation of response to external stimulus#GO:0032101;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000011036.3|UniProtKB=G3R623 G3R623 TTC16 PTHR45153:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 16 TETRATRICOPEPTIDE REPEAT PROTEIN 16 GORGO|Ensembl=ENSGGOG00000037205.1|UniProtKB=A0A2I2Z8X8 A0A2I2Z8X8 PTHR19343:SF26 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 1-1 peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000015736.3|UniProtKB=G3RI63 G3RI63 NHLH1 PTHR13864:SF20 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED HELIX-LOOP-HELIX PROTEIN 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000010791.3|UniProtKB=G3R5E9 G3R5E9 KIAA2012 PTHR21937:SF5 CCDC66 DOMAIN-CONTAINING PROTEIN GENE 973-RELATED GORGO|Ensembl=ENSGGOG00000011938.3|UniProtKB=A0A2I2YMZ7 A0A2I2YMZ7 TDRD12 PTHR22655:SF2 ATP-DEPENDENT RNA HELICASE TDRD12-RELATED ATP-DEPENDENT RNA HELICASE TDRD12-RELATED macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;piRNA processing#GO:0034587;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000005983.3|UniProtKB=G3SD62 G3SD62 FANCC PTHR16798:SF0 FANCONI ANEMIA GROUP C PROTEIN FANCC FANCONI ANEMIA GROUP C PROTEIN cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013100.3|UniProtKB=G3RBD5 G3RBD5 DNAAF5 PTHR16216:SF11 DYNEIN ASSEMBLY FACTOR 5, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 5 protein binding#GO:0005515;binding#GO:0005488 microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;inner dynein arm assembly#GO:0036159;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000002353.3|UniProtKB=G3QIU7 G3QIU7 QPCTL PTHR12283:SF6 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIKE PROTEIN zinc ion binding#GO:0008270;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transition metal ion binding#GO:0046914;acyltransferase activity#GO:0016746;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000006565.3|UniProtKB=G3QUM2 G3QUM2 VPS52 PTHR14190:SF16 SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG protein binding#GO:0005515;syntaxin binding#GO:0019905;binding#GO:0005488;SNARE binding#GO:0000149 endocytic recycling#GO:0032456;cytosolic transport#GO:0016482;localization#GO:0051179;cellular localization#GO:0051641;lysosomal transport#GO:0007041;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013807.3|UniProtKB=G3RD76 G3RD76 ATF6 PTHR46164:SF1 ATF6, ISOFORM C CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-6 ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 Apoptosis signaling pathway#P00006>ATF#P00302 GORGO|Ensembl=ENSGGOG00000006905.3|UniProtKB=G3QVI6 G3QVI6 TMBIM1 PTHR23291:SF35 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857 response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to unfolded protein#GO:0006986;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;negative regulation of signal transduction#GO:0009968;response to stress#GO:0006950;negative regulation of neuron apoptotic process#GO:0043524;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;regulation of apoptotic signaling pathway#GO:2001233;cellular response to topologically incorrect protein#GO:0035967;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000013703.3|UniProtKB=G3RQJ8 G3RQJ8 INSR PTHR24416:SF535 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN RECEPTOR transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888 cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;carbohydrate homeostasis#GO:0033500;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;glucose homeostasis#GO:0042593;cell surface receptor signaling pathway#GO:0007166;chemical homeostasis#GO:0048878;regulation of MAPK cascade#GO:0043408;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;homeostatic process#GO:0042592;positive regulation of signal transduction#GO:0009967;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;response to nitrogen compound#GO:1901698;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;positive regulation of intracellular signal transduction#GO:1902533 protein kinase complex#GO:1902911;signaling receptor complex#GO:0043235;transferase complex#GO:1990234;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;catalytic complex#GO:1902494;axon#GO:0030424;transferase complex, transferring phosphorus-containing groups#GO:0061695;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>IR#P06802;PI3 kinase pathway#P00048>IR#P01187;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895 GORGO|Ensembl=ENSGGOG00000009991.4|UniProtKB=G3R3H2 G3R3H2 BLTP1 PTHR31640:SF1 TRANSMEMBRANE PROTEIN KIAA1109 BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 1 synaptic vesicle cycle#GO:0099504;transport#GO:0006810;import into cell#GO:0098657;cellular localization#GO:0051641;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;localization#GO:0051179;synaptic vesicle endocytosis#GO:0048488;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endocytosis#GO:0006897;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192 GORGO|Ensembl=ENSGGOG00000000074.3|UniProtKB=G3QCX1 G3QCX1 CSNK1D PTHR11909:SF519 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM DELTA kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;positive regulation of signal transduction#GO:0009967;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;cell communication#GO:0007154;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;non-motile cilium assembly#GO:1905515;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of response to stimulus#GO:0048584;regulation of circadian rhythm#GO:0042752;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;positive regulation of canonical Wnt signaling pathway#GO:0090263;spindle organization#GO:0007051;positive regulation of catabolic process#GO:0009896;regulation of response to stimulus#GO:0048583;plasma membrane bounded cell projection assembly#GO:0120031;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;positive regulation of proteasomal protein catabolic process#GO:1901800;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cilium assembly#GO:0060271;cilium organization#GO:0044782;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;cytoskeleton organization#GO:0007010;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of Wnt signaling pathway#GO:0030177;regulation of proteasomal protein catabolic process#GO:0061136;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167 Parkinson disease#P00049>Casein kinase I#P01242;Circadian clock system#P00015>Casein kinase I#P00502;Wnt signaling pathway#P00057>Casein Kinase 1#P01460;CCKR signaling map#P06959>CK1delta/epsilon#P07089 GORGO|Ensembl=ENSGGOG00000010197.3|UniProtKB=A0A2I2Z5Z8 A0A2I2Z5Z8 GFPT2 PTHR10937:SF10 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2 transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 transaminase#PC00216 N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042;O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051 GORGO|Ensembl=ENSGGOG00000023234.2|UniProtKB=G3S729 G3S729 IFIT1 PTHR10271:SF34 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS ANTIVIRAL INNATE IMMUNE RESPONSE EFFECTOR IFIT1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 immune system process#GO:0002376;response to peptide#GO:1901652;response to virus#GO:0009615;cellular response to cytokine stimulus#GO:0071345;antiviral innate immune response#GO:0140374;defense response to virus#GO:0051607;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000003068.3|UniProtKB=A0A2I2ZQI6 A0A2I2ZQI6 CAMKK1 PTHR24343:SF569 SERINE/THREONINE KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015243.3|UniProtKB=G3RGV8 G3RGV8 NPBWR1 PTHR24229:SF47 NEUROPEPTIDES RECEPTOR NEUROPEPTIDES B_W RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000022747.2|UniProtKB=A0A2I2ZFG2 A0A2I2ZFG2 PTHR48012:SF9 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 25 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000008070.3|UniProtKB=G3QYF4 G3QYF4 CCRL2 PTHR10489:SF655 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR-LIKE 2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell communication#GO:0007154;inflammatory response#GO:0006954;chemotaxis#GO:0006935;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;defense response#GO:0006952;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950 side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;external side of plasma membrane#GO:0009897;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000013437.3|UniProtKB=G3RCA5 G3RCA5 COP1 PTHR44080:SF1 E3 UBIQUITIN-PROTEIN LIGASE COP1 E3 UBIQUITIN-PROTEIN LIGASE COP1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 P53 pathway feedback loops 1#P04392>Cop-1#P04540;P53 pathway feedback loops 1#P04392>Cop-1#G04683 GORGO|Ensembl=ENSGGOG00000017005.3|UniProtKB=A0A2I2ZX61 A0A2I2ZX61 SMCHD1 PTHR22640:SF3 STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1 STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;chromosome#GO:0005694;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000022491.2|UniProtKB=G3RZ81 G3RZ81 PTHR10369:SF32 60S RIBOSOMAL PROTEIN L36A/L44 60S RIBOSOMAL PROTEIN L36A-LIKE structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013169.3|UniProtKB=G3RBJ3 G3RBJ3 HARS1 PTHR11476:SF8 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;nucleic acid binding#GO:0003676;binding#GO:0005488 mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;translation#GO:0006412;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000005317.3|UniProtKB=A0A2I2ZSQ4 A0A2I2ZSQ4 PDE8B PTHR11347:SF98 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8B catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112 positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519 phosphodiesterase#PC00185;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000036598.1|UniProtKB=A0A2I2YYX7 A0A2I2YYX7 PTHR31905:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 SUBFAMILY NOT NAMED mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011451.3|UniProtKB=G3R741 G3R741 PALS1 PTHR23122:SF14 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PROTEIN PALS1 intracellular protein localization#GO:0008104;neurogenesis#GO:0022008;morphogenesis of an epithelium#GO:0002009;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;protein localization to cell periphery#GO:1990778;nervous system development#GO:0007399;embryo development#GO:0009790;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cellular process#GO:0009987;macromolecule localization#GO:0033036;system development#GO:0048731;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;tissue morphogenesis#GO:0048729;localization#GO:0051179;anatomical structure development#GO:0048856;cellular localization#GO:0051641;generation of neurons#GO:0048699;localization within membrane#GO:0051668;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659 anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009103.3|UniProtKB=G3R147 G3R147 TRIM72 PTHR24103:SF11 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 72 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;response to stimulus#GO:0050896;catabolic process#GO:0009056;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;immune system process#GO:0002376;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987;defense response to other organism#GO:0098542;response to other organism#GO:0051707;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;ubiquitin-dependent protein catabolic process#GO:0006511 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;sarcolemma#GO:0042383;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000005587.3|UniProtKB=G3QS47 G3QS47 ZNF277 PTHR13267:SF3 ZINC FINGER PROTEIN 277 ZINC FINGER PROTEIN 277 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000022862.2|UniProtKB=A0A2I2Z7C8 A0A2I2Z7C8 PTHR10351:SF57 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000040087.1|UniProtKB=G3RS27 G3RS27 PTHR10370:SF0 ERYTHROPOIETIN ERYTHROPOIETIN hormone activity#GO:0005179;kinase activator activity#GO:0019209;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein kinase activator activity#GO:0030295;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;binding#GO:0005488;cytokine receptor binding#GO:0005126;kinase regulator activity#GO:0019207;signaling receptor activator activity#GO:0030546;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047 multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor signaling pathway via STAT#GO:0097696;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to peptide#GO:1901652;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;cell communication#GO:0007154;homeostasis of number of cells#GO:0048872;cytokine-mediated signaling pathway#GO:0019221;immune system process#GO:0002376;cell development#GO:0048468;signaling#GO:0023052;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000008126.3|UniProtKB=G3QYK4 G3QYK4 LEMD2 PTHR13428:SF8 INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN LEM DOMAIN-CONTAINING PROTEIN 2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682 cellular component assembly#GO:0022607;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;membrane assembly#GO:0071709;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;nuclear envelope organization#GO:0006998 organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007469.3|UniProtKB=G3SCG8 G3SCG8 KAT7 PTHR10615:SF222 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT7 N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;histone acetyltransferase activity#GO:0004402;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transcription regulator activity#GO:0140110;acetyltransferase activity#GO:0016407;binding#GO:0005488;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137 GORGO|Ensembl=ENSGGOG00000013070.3|UniProtKB=G3RBB2 G3RBB2 LDB3 PTHR24214:SF9 PDZ AND LIM DOMAIN PROTEIN ZASP LIM DOMAIN-BINDING PROTEIN 3 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;multicellular organismal process#GO:0032501;heart development#GO:0007507;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;circulatory system development#GO:0072359;cellular component organization#GO:0016043 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;adherens junction#GO:0005912;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;sarcomere#GO:0030017;actin filament#GO:0005884;I band#GO:0031674;stress fiber#GO:0001725;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;actomyosin#GO:0042641;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cell-cell junction#GO:0005911 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000003517.3|UniProtKB=G3QLU0 G3QLU0 FOXO3 PTHR45767:SF4 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O3-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 winged helix/forkhead transcription factor#PC00246 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>FKHR#P00898;Interleukin signaling pathway#P00036>FKHRL1#P00994;PI3 kinase pathway#P00048>FOXO#P01198;CCKR signaling map#P06959>FOXO3#P07073 GORGO|Ensembl=ENSGGOG00000010467.3|UniProtKB=G3R4M0 G3R4M0 ATP2B4 PTHR24093:SF435 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 4 ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662 regulation of cytosolic calcium ion concentration#GO:0051480;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082 cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000007585.3|UniProtKB=A0A2I2Z8F1 A0A2I2Z8F1 DLGAP2 PTHR12353:SF3 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 2 biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051 cell junction#GO:0030054;organelle#GO:0043226;postsynaptic specialization#GO:0099572;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001651.3|UniProtKB=A0A2I2YVA5 A0A2I2YVA5 NCOR1 PTHR13992:SF5 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR NUCLEAR RECEPTOR COREPRESSOR 1 transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription coregulator activity#GO:0003712;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>N-CoR#P00770 GORGO|Ensembl=ENSGGOG00000010654.3|UniProtKB=G3RYX4 G3RYX4 LOC101141122 PTHR24250:SF65 CHYMOTRYPSIN-RELATED CHYMOTRYPSINOGEN B serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 protein modifying enzyme#PC00260;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000015101.3|UniProtKB=G3RGI1 G3RGI1 SCT PTHR17378:SF1 SECRETIN SECRETIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of hormone secretion#GO:0046883;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;positive regulation of multicellular organismal process#GO:0051240;negative regulation of biological process#GO:0048519;central nervous system development#GO:0007417;regulation of body fluid levels#GO:0050878;regulation of localization#GO:0032879;regulation of transport#GO:0051049;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of multicellular organismal process#GO:0051239;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of hormone secretion#GO:0046887;system development#GO:0048731;regulation of secretion#GO:0051046;anatomical structure development#GO:0048856;negative regulation of multicellular organismal process#GO:0051241;regulation of cell communication#GO:0010646;negative regulation of transport#GO:0051051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of system process#GO:0044057;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;brain development#GO:0007420;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000002135.3|UniProtKB=G3QI98 G3QI98 AK8 PTHR23359:SF271 NUCLEOTIDE KINASE ADENYLATE KINASE 8 transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 ADP metabolic process#GO:0046031;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside diphosphate metabolic process#GO:0009179;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;nucleoside diphosphate metabolic process#GO:0009132;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153;De novo purine biosynthesis#P02738>Adenylate kinase#P02896 GORGO|Ensembl=ENSGGOG00000007036.3|UniProtKB=G3QVU9 G3QVU9 PTPN1 PTHR46047:SF2 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cellular process#GO:0050794;negative regulation of MAPK cascade#GO:0043409;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 intracellular vesicle#GO:0097708;nucleus#GO:0005634;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endosome#GO:0005768;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Cadherin signaling pathway#P00012>Tyrosine phosphatases#P00472 GORGO|Ensembl=ENSGGOG00000034916.2|UniProtKB=G3SKU9 G3SKU9 STXBP5L PTHR10241:SF19 LETHAL 2 GIANT LARVAE PROTEIN SYNTAXIN-BINDING PROTEIN 5-LIKE molecular function activator activity#GO:0140677;syntaxin binding#GO:0019905;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;binding#GO:0005488;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;SNARE binding#GO:0000149;enzyme activator activity#GO:0008047 export from cell#GO:0140352;Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;exocytosis#GO:0006887;vesicle-mediated transport to the plasma membrane#GO:0098876;post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;cellular localization#GO:0051641;localization within membrane#GO:0051668;transport#GO:0006810;Golgi vesicle transport#GO:0048193 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000012646.3|UniProtKB=G3RA78 G3RA78 GET4 PTHR12875:SF3 GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000014159.3|UniProtKB=G3RE50 G3RE50 MCM10 PTHR13454:SF11 PROTEIN MCM10 HOMOLOG PROTEIN MCM10 HOMOLOG DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596 GORGO|Ensembl=ENSGGOG00000004164.3|UniProtKB=A0A2I2Z6B0 A0A2I2Z6B0 DBNDD2 PTHR16294:SF7 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN DOMAIN-CONTAINING PROTEIN 2 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646 GORGO|Ensembl=ENSGGOG00000015936.3|UniProtKB=G3RIN4 G3RIN4 PTHR13952:SF31 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 35 KDA PROTEIN mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000002713.3|UniProtKB=G3QJS5 G3QJS5 SREBF1 PTHR46062:SF2 STEROL REGULATORY ELEMENT-BINDING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000027808.2|UniProtKB=G3S203 G3S203 PRR33 PTHR38004:SF1 PROLINE-RICH PROTEIN 33 PROLINE-RICH PROTEIN 33 GORGO|Ensembl=ENSGGOG00000003007.3|UniProtKB=G3QKI1 G3QKI1 WFDC5 PTHR19441:SF39 WAP four-disulfide core domain protein WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 5 serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000010116.3|UniProtKB=A0A2I2ZK03 A0A2I2ZK03 WSCD2 PTHR45964:SF9 WSCD FAMILY MEMBER CG9164 SIALATE:O-SULFOTRANSFERASE 2 GORGO|Ensembl=ENSGGOG00000006006.3|UniProtKB=G3QT73 G3QT73 MCMBP PTHR13489:SF0 MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN chromatin binding#GO:0003682;binding#GO:0005488 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139 GORGO|Ensembl=ENSGGOG00000024259.2|UniProtKB=G3RXJ5 G3RXJ5 FAM111A PTHR14389:SF14 SI:CH1073-475A24.1 SERINE PROTEASE FAM111A catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000026888.2|UniProtKB=G3RU18 G3RU18 POLR1F PTHR12709:SF5 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription by RNA polymerase I#GO:0006360;DNA-templated transcription elongation#GO:0006354;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014059.3|UniProtKB=G3RDW4 G3RDW4 CLEC16A PTHR21481:SF0 PROTEIN CLEC16A PROTEIN CLEC16A intracellular transport#GO:0046907;transport#GO:0006810;regulation of autophagosome maturation#GO:1901096;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;regulation of catabolic process#GO:0009894;regulation of macroautophagy#GO:0016241;endosomal transport#GO:0016197;regulation of metabolic process#GO:0019222;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;cellular localization#GO:0051641;localization#GO:0051179;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000006057.3|UniProtKB=G3RM06 G3RM06 CLPB PTHR11638:SF93 ATP-DEPENDENT CLP PROTEASE MITOCHONDRIAL DISAGGREGASE ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000043616.1|UniProtKB=G3RYP9 G3RYP9 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;regulation of protein stability#GO:0031647;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000014669.3|UniProtKB=G3RFE2 G3RFE2 CRYGN PTHR11818:SF22 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN N structural molecule activity#GO:0005198 visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000007902.3|UniProtKB=G3S0H1 G3S0H1 GUSB PTHR10066:SF69 BETA-GLUCURONIDASE BETA-GLUCURONIDASE binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;carbohydrate binding#GO:0030246;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;glycosaminoglycan metabolic process#GO:0030203;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;glycosaminoglycan catabolic process#GO:0006027;protein catabolic process#GO:0030163;aminoglycan metabolic process#GO:0006022;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000012619.3|UniProtKB=G3RA53 G3RA53 IDH1 PTHR11822:SF28 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide metabolic process#GO:0009117;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleotide metabolic process#GO:0006163;NADP+ metabolic process#GO:0006739;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;microbody#GO:0042579;peroxisome#GO:0005777;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000002998.3|UniProtKB=G3QKH4 G3QKH4 SMG8 PTHR13091:SF0 AMPLIFIED IN BREAST CANCER 2-RELATED NONSENSE-MEDIATED MRNA DECAY FACTOR SMG8 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139 GORGO|Ensembl=ENSGGOG00000016486.3|UniProtKB=G3RK33 G3RK33 PTHR12114:SF1 PARVIN GAMMA-PARVIN protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;substrate adhesion-dependent cell spreading#GO:0034446;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of biological quality#GO:0065008;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;regulation of developmental process#GO:0050793;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;cellular component organization#GO:0016043 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;cell-substrate junction#GO:0030055;intracellular membraneless organelle#GO:0043232;focal adhesion#GO:0005925 actin and actin related protein#PC00039;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000036669.1|UniProtKB=A0A2I2ZS81 A0A2I2ZS81 PTHR12854:SF8 ATAXIN 2-RELATED ATAXIN-2-LIKE PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010247.3|UniProtKB=G3RWJ5 G3RWJ5 SIK2 PTHR24346:SF38 MAP/MICROTUBULE AFFINITY-REGULATING KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001421.3|UniProtKB=G3QGE9 G3QGE9 NAB2 PTHR12623:SF6 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 GORGO|Ensembl=ENSGGOG00000013093.3|UniProtKB=A0A2I2Z570 A0A2I2Z570 PTHR23220:SF21 INTEGRIN ALPHA INTEGRIN ALPHA-11 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000002418.3|UniProtKB=G3QJ06 G3QJ06 CDS1 PTHR13773:SF16 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular component assembly#GO:0022607;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid storage#GO:0019915;organophosphate metabolic process#GO:0019637;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;organophosphate biosynthetic process#GO:0090407;lipid droplet organization#GO:0034389;organelle assembly#GO:0070925 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000026542.2|UniProtKB=G3S0Z3 G3S0Z3 UGT8 PTHR48043:SF54 EG:EG0003.4 PROTEIN-RELATED 2-HYDROXYACYLSPHINGOSINE 1-BETA-GALACTOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 glycosphingolipid biosynthetic process#GO:0006688;ceramide metabolic process#GO:0006672;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;carbohydrate derivative biosynthetic process#GO:1901137;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000002234.3|UniProtKB=G3QIJ4 G3QIJ4 PTHR24096:SF296 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ACSBG1 ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000008812.3|UniProtKB=G3SG23 G3SG23 PTHR10075:SF124 BASIGIN RELATED NEOGENIN cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000011061.3|UniProtKB=A0A2I2ZQC6 A0A2I2ZQC6 TPGS2 PTHR31854:SF2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000014289.3|UniProtKB=A0A2I2ZHF8 A0A2I2ZHF8 ZNF619 PTHR24381:SF138 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 619 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000014883.3|UniProtKB=A0A2I2YVF1 A0A2I2YVF1 NARF PTHR11615:SF124 NITRATE, FORMATE, IRON DEHYDROGENASE NUCLEAR PRELAMIN A RECOGNITION FACTOR protein binding#GO:0005515;binding#GO:0005488 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;iron-sulfur cluster assembly#GO:0016226 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;intracellular protein-containing complex#GO:0140535;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000006377.3|UniProtKB=G3QU41 G3QU41 APOE PTHR18976:SF2 APOLIPOPROTEIN APOLIPOPROTEIN E binding#GO:0005488;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;lipid transfer activity#GO:0120013;enzyme regulator activity#GO:0030234;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;cholesterol transfer activity#GO:0120020;molecular function regulator activity#GO:0098772 sterol metabolic process#GO:0016125;sterol transport#GO:0015918;establishment of localization#GO:0051234;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;cholesterol metabolic process#GO:0008203;transport#GO:0006810;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;steroid metabolic process#GO:0008202;phospholipid transport#GO:0015914;lipid transport#GO:0006869;cellular process#GO:0009987;cholesterol efflux#GO:0033344;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;lipid localization#GO:0010876;homeostatic process#GO:0042592;secondary alcohol metabolic process#GO:1902652;organophosphate ester transport#GO:0015748;small molecule metabolic process#GO:0044281;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;very-low-density lipoprotein particle#GO:0034361;high-density lipoprotein particle#GO:0034364;membrane-bounded organelle#GO:0043227;plasma lipoprotein particle#GO:0034358;lipoprotein particle#GO:1990777;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;extracellular region#GO:0005576 apolipoprotein#PC00052;transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000043634.1|UniProtKB=A0A2I2Y6N3 A0A2I2Y6N3 ATG2A PTHR13190:SF21 AUTOPHAGY-RELATED 2, ISOFORM A AUTOPHAGY-RELATED PROTEIN 2 HOMOLOG A protein-membrane adaptor activity#GO:0043495;lipid binding#GO:0008289;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090 cellular component assembly#GO:0022607;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;reticulophagy#GO:0061709;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;carbohydrate metabolic process#GO:0005975;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;phagophore assembly site#GO:0000407 GORGO|Ensembl=ENSGGOG00000004344.3|UniProtKB=G3QNY1 G3QNY1 SLC19A3 PTHR10686:SF37 FOLATE TRANSPORTER THIAMINE TRANSPORTER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000015248.3|UniProtKB=A0A2I2ZTJ3 A0A2I2ZTJ3 EPHB4 PTHR24416:SF296 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-B RECEPTOR 4 transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888 blood vessel morphogenesis#GO:0048514;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;ephrin receptor signaling pathway#GO:0048013;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;system development#GO:0048731;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025224.2|UniProtKB=G3RWB8 G3RWB8 PARN PTHR15092:SF44 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 POLY(A)-SPECIFIC RIBONUCLEASE PARN 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000000990.3|UniProtKB=G3QFA9 G3QFA9 REM1 PTHR45775:SF2 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN REM 1 calcium channel regulator activity#GO:0005246;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000040481.1|UniProtKB=A0A2I2Z1S9 A0A2I2Z1S9 PTHR28599:SF3 SMALL INTEGRAL MEMBRANE PROTEIN 12 SMALL INTEGRAL MEMBRANE PROTEIN 12 GORGO|Ensembl=ENSGGOG00000005221.3|UniProtKB=G3QR79 G3QR79 USP31 PTHR21646:SF44 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 31 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000005041.3|UniProtKB=G3QQR2 G3QQR2 OR52I2 PTHR26450:SF177 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52I1-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012960.3|UniProtKB=G3RB11 G3RB11 MAP3K13 PTHR23257:SF945 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 13 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000002254.3|UniProtKB=Q864V9 Q864V9 CFB PTHR46393:SF1 SUSHI DOMAIN-CONTAINING PROTEIN COMPLEMENT FACTOR B response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;humoral immune response#GO:0006959;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune response#GO:0006955;complement activation#GO:0006956;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000007091.3|UniProtKB=G3QVZ6 G3QVZ6 IL20RB PTHR20859:SF48 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-20 RECEPTOR SUBUNIT BETA cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;signaling#GO:0023052;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007043.3|UniProtKB=G3QVW5 G3QVW5 RIPOR3 PTHR15829:SF15 PROTEIN KINASE PKN/PRK1, EFFECTOR RIPOR FAMILY MEMBER 3 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000042822.1|UniProtKB=A0A2I2YGP3 A0A2I2YGP3 B4GALT5 PTHR19300:SF45 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 5 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;biosynthetic process#GO:0009058;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000468.3|UniProtKB=A0A2I2YZF7 A0A2I2YZF7 BAALC PTHR14731:SF0 BRAIN AND ACUTE LEUKEMIA CYTOPLASMIC PROTEIN BRAIN AND ACUTE LEUKEMIA CYTOPLASMIC PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000001647.3|UniProtKB=G3SDJ4 G3SDJ4 TTC19 PTHR13143:SF6 TETRATRICOPEPTIDE REPEAT PROTEIN 19 TETRATRICOPEPTIDE REPEAT PROTEIN 19, MITOCHONDRIAL cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000041084.1|UniProtKB=A0A2I2ZLJ2 A0A2I2ZLJ2 RPL22L1 PTHR10064:SF1 60S RIBOSOMAL PROTEIN L22 RIBOSOMAL PROTEIN EL22-LIKE structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000016863.3|UniProtKB=G3RL19 G3RL19 KRT32 PTHR23239:SF155 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA2 structural molecule activity#GO:0005198 intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cellular process#GO:0009987;organelle organization#GO:0006996;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000007286.3|UniProtKB=A0A2I2Z203 A0A2I2Z203 ASB11 PTHR24136:SF14 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 11 macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000007698.3|UniProtKB=G3QXI9 G3QXI9 DNALI1 PTHR13183:SF4 AXONEMAL INNER ARM DYNEIN LIGHT CHAIN 28 AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1 protein binding#GO:0005515;binding#GO:0005488 membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;ciliary base#GO:0097546 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000026243.2|UniProtKB=G3S569 G3S569 ND2 PTHR46552:SF1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055;NADH dehydrogenase activity#GO:0003954;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010960.3|UniProtKB=G3R5V1 G3R5V1 ZNF276 PTHR24406:SF3 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER PROTEIN 276 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000009421.2|UniProtKB=G3R1X2 G3R1X2 MAGEB5 PTHR11736:SF35 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B5 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000044208.1|UniProtKB=A0A2I2ZT65 A0A2I2ZT65 PTHR10293:SF74 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-3 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;cellular component organization or biogenesis#GO:0071840;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;monoatomic ion homeostasis#GO:0050801;inorganic ion homeostasis#GO:0098771;iron-sulfur cluster assembly#GO:0016226;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000009721.3|UniProtKB=Q2IBF4 Q2IBF4 WNT2 PTHR12027:SF86 WNT RELATED PROTEIN WNT-2 G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell fate commitment#GO:0045165;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 GORGO|Ensembl=ENSGGOG00000006852.3|UniProtKB=G3QVE0 G3QVE0 FBXO34 PTHR16271:SF11 F-BOX ONLY PROTEIN 34/46 FAMILY MEMBER F-BOX ONLY PROTEIN 34 GORGO|Ensembl=ENSGGOG00000027102.2|UniProtKB=A0A2I2Y363 A0A2I2Y363 LRRC34 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 cellular process#GO:0009987;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 GORGO|Ensembl=ENSGGOG00000010733.3|UniProtKB=G3R598 G3R598 SH3D19 PTHR14167:SF48 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN 19 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000013938.3|UniProtKB=A0A2I2YY63 A0A2I2YY63 ANAPC11 PTHR11210:SF1 RING BOX ANAPHASE-PROMOTING COMPLEX SUBUNIT 11 protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;protein modification by small protein conjugation#GO:0032446;regulation of organelle organization#GO:0033043;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;positive regulation of cell cycle#GO:0045787;regulation of chromosome separation#GO:1905818;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;regulation of mitotic metaphase/anaphase transition#GO:0030071 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000014764.3|UniProtKB=G3RFN5 G3RFN5 NCK2 PTHR19969:SF12 SH2-SH3 ADAPTOR PROTEIN-RELATED CYTOPLASMIC PROTEIN NCK2 molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 regulation of apoptotic signaling pathway#GO:2001233;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to endoplasmic reticulum stress#GO:0034976;positive regulation of translation#GO:0045727;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of intrinsic apoptotic signaling pathway#GO:2001242;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stress#GO:0080134;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell migration#GO:0016477;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;negative regulation of signal transduction#GO:0009968;positive regulation of macromolecule metabolic process#GO:0010604 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Nck#P01147;Angiogenesis#P00005>Nck#P00215;T cell activation#P00053>nck#P01314 GORGO|Ensembl=ENSGGOG00000016919.3|UniProtKB=G3RL71 G3RL71 PEX11A PTHR12652:SF22 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11A cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;organelle organization#GO:0006996;cellular component organization#GO:0016043;peroxisome organization#GO:0007031;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000006659.3|UniProtKB=A0A2I2Z1L9 A0A2I2Z1L9 MYOF PTHR12546:SF55 FER-1-LIKE MYOFERLIN phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 response to wounding#GO:0009611;response to stress#GO:0006950;membrane fusion#GO:0061025;cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;plasma membrane organization#GO:0007009;wound healing#GO:0042060 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000016005.3|UniProtKB=G3RIU4 G3RIU4 PTHR13254:SF2 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 GOLGIN SUBFAMILY A MEMBER 7B protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000000177.3|UniProtKB=G3QD65 G3QD65 ABTB1 PTHR46231:SF1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 GORGO|Ensembl=ENSGGOG00000040459.1|UniProtKB=A0A2I2YY41 A0A2I2YY41 PTHR13906:SF7 PORCUPINE MEMBRANE-BOUND GLYCEROPHOSPHOLIPID O-ACYLTRANSFERASE 2 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258 membrane#GO:0016020;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000000077.3|UniProtKB=G3QCX4 G3QCX4 FAM168B PTHR31844:SF2 MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR-RELATED MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR structural protein#PC00211;myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000011932.3|UniProtKB=G3R8D3 G3R8D3 EBI3 PTHR48483:SF2 INTERLEUKIN-27 SUBUNIT BETA INTERLEUKIN-27 SUBUNIT BETA protein binding#GO:0005515;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102 T cell proliferation#GO:0042098;immune system process#GO:0002376;cell activation#GO:0001775;cell population proliferation#GO:0008283;leukocyte proliferation#GO:0070661;T cell activation#GO:0042110;leukocyte activation#GO:0045321;cellular process#GO:0009987;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;lymphocyte proliferation#GO:0046651;mononuclear cell proliferation#GO:0032943 GORGO|Ensembl=ENSGGOG00000017152.3|UniProtKB=G3RLS9 G3RLS9 TESK1 PTHR46485:SF3 LIM DOMAIN KINASE 1 DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;positive regulation of organelle organization#GO:0010638;actin filament-based process#GO:0030029;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;organelle organization#GO:0006996;positive regulation of actin filament bundle assembly#GO:0032233;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000003652.3|UniProtKB=G3QM60 G3QM60 THRSP PTHR14315:SF18 SPOT14 FAMILY MEMBER THYROID HORMONE-INDUCIBLE HEPATIC PROTEIN molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 regulation of lipid metabolic process#GO:0019216;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002658.3|UniProtKB=G3RYP2 G3RYP2 ZNF385A PTHR23067:SF13 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385A membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000003982.3|UniProtKB=G3QN07 G3QN07 CAPZB PTHR10619:SF2 F-ACTIN-CAPPING PROTEIN SUBUNIT BETA F-ACTIN-CAPPING PROTEIN SUBUNIT BETA protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of actin filament depolymerization#GO:0030834;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000008393.3|UniProtKB=G3QZ96 G3QZ96 UBE2E1 PTHR24068:SF70 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;ISG15-protein conjugation#GO:0032020;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein K48-linked ubiquitination#GO:0070936;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000025851.2|UniProtKB=G3SAP1 G3SAP1 PTHR24056:SF130 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 6 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006741.3|UniProtKB=G3QV36 G3QV36 CHEK1 PTHR24343:SF540 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE CHK1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003848.2|UniProtKB=G3QMN3 G3QMN3 LOC101140082 PTHR26453:SF4 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006883.3|UniProtKB=G3QVG6 G3QVG6 AAMP PTHR19857:SF27 MITOCHONDRIAL DIVISION PROTEIN 1-RELATED ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 cell adhesion#GO:0007155;cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000023994.2|UniProtKB=A0A2I2ZG27 A0A2I2ZG27 CENPB PTHR19303:SF69 TRANSPOSON MAJOR CENTROMERE AUTOANTIGEN B DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000006053.3|UniProtKB=G3QTA9 G3QTA9 AKIRIN1 PTHR13293:SF9 AKIRIN-RELATED AKIRIN-1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;tissue regeneration#GO:0042246;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;regulation of chemotaxis#GO:0050920;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of cell differentiation#GO:0045597;growth#GO:0040007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;positive regulation of cellular component biogenesis#GO:0044089;regeneration#GO:0031099;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of immune response#GO:0050776;positive regulation of cell projection organization#GO:0031346;regulation of defense response#GO:0031347;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of immune system process#GO:0002682;positive regulation of RNA metabolic process#GO:0051254;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;developmental growth#GO:0048589;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of locomotion#GO:0040017;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of primary metabolic process#GO:0080090;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of metabolic process#GO:0009893;positive regulation of cellular component organization#GO:0051130;positive regulation of cell motility#GO:2000147;positive regulation of response to external stimulus#GO:0032103;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of biosynthetic process#GO:0009891;regulation of cell motility#GO:2000145;regulation of DNA-templated transcription#GO:0006355;positive regulation of chemotaxis#GO:0050921;regulation of cell projection assembly#GO:0060491;regulation of granulocyte chemotaxis#GO:0071622;regulation of leukocyte migration#GO:0002685;regulation of developmental process#GO:0050793;regulation of response to biotic stimulus#GO:0002831;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;developmental process#GO:0032502;cell migration#GO:0016477;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of innate immune response#GO:0045089 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 GORGO|Ensembl=ENSGGOG00000010775.3|UniProtKB=A0A2I2Y3Q6 A0A2I2Y3Q6 PIDD1 PTHR45752:SF44 LEUCINE-RICH REPEAT-CONTAINING P53-INDUCED DEATH DOMAIN-CONTAINING PROTEIN 1 programmed cell death#GO:0012501;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037539.1|UniProtKB=A0A2I2ZMS0 A0A2I2ZMS0 PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-N7 METHYLTRANSFERASE ACTIVATING SUBUNIT-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;enzyme activator activity#GO:0008047 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000002703.3|UniProtKB=G3QJR1 G3QJR1 LHX1 PTHR24208:SF106 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004763.3|UniProtKB=G3QQ10 G3QQ10 SPG21 PTHR15913:SF1 ACID CLUSTER PROTEIN 33 MASPARDIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytosol#GO:0005829;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;trans-Golgi network transport vesicle#GO:0030140 GORGO|Ensembl=ENSGGOG00000026929.2|UniProtKB=G3SHA9 G3SHA9 USP26 PTHR24006:SF911 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 26 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;regulation of protein stability#GO:0031647;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;biological regulation#GO:0065007;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;regulation of biological quality#GO:0065008;mitotic cell cycle process#GO:1903047 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000005013.3|UniProtKB=G3QQP1 G3QQP1 IL17RD PTHR15583:SF14 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR D transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010771.3|UniProtKB=G3R5D2 G3R5D2 GLRX3 PTHR10293:SF74 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-3 oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 inorganic ion homeostasis#GO:0098771;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;intracellular iron ion homeostasis#GO:0006879;iron-sulfur cluster assembly#GO:0016226;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cellular component organization or biogenesis#GO:0071840;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000011422.3|UniProtKB=A0A2I2YV86 A0A2I2YV86 PTS PTHR12589:SF10 PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE 6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007695.3|UniProtKB=G3QXI6 G3QXI6 GBP7 PTHR10751:SF138 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 7 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 G-protein#PC00020;heterotrimeric G-protein#PC00117 GORGO|Ensembl=ENSGGOG00000004537.3|UniProtKB=G3QPF5 G3QPF5 SPATA32 PTHR37338:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 32 SPERMATOGENESIS-ASSOCIATED PROTEIN 32 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;multicellular organismal reproductive process#GO:0048609 cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000012770.3|UniProtKB=A0A2I2YZT7 A0A2I2YZT7 DCTN1 PTHR18916:SF95 DYNACTIN 1-RELATED MICROTUBULE-BINDING DYNACTIN SUBUNIT 1 mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;nuclear migration#GO:0007097;establishment of cell polarity#GO:0030010;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;spindle localization#GO:0051653;establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;cytoskeleton organization#GO:0007010;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;mitotic cell cycle process#GO:1903047;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;transport#GO:0006810;intracellular transport#GO:0046907 microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;neuron projection#GO:0043005;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;spindle#GO:0005819;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687 chaperone#PC00072 Huntington disease#P00029>Dynactin#P00781 GORGO|Ensembl=ENSGGOG00000003766.3|UniProtKB=G3QMF8 G3QMF8 TEKT2 PTHR19960:SF29 TEKTIN TEKTIN-2 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000023120.2|UniProtKB=G3SIE7 G3SIE7 RALBP1 PTHR12783:SF5 RALA BINDING PROTEIN 1 RALBP1 RALA-BINDING PROTEIN 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 signal transduction#GO:0007165;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000010388.3|UniProtKB=G3R4E2 G3R4E2 RASAL1 PTHR10194:SF3 RAS GTPASE-ACTIVATING PROTEINS RASGAP-ACTIVATING-LIKE PROTEIN 1 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646;EGF receptor signaling pathway#P00018>GAP#P00546 GORGO|Ensembl=ENSGGOG00000004993.3|UniProtKB=A0A2I2Y694 A0A2I2Y694 TRPS1 PTHR47034:SF1 ZINC FINGER TRANSCRIPTION FACTOR TRPS1 ZINC FINGER TRANSCRIPTION FACTOR TRPS1 transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000001183.3|UniProtKB=G3QFT8 G3QFT8 TAF1A PTHR32122:SF1 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>SL1 complex#P00653 GORGO|Ensembl=ENSGGOG00000016620.3|UniProtKB=G3RSZ7 G3RSZ7 PTHR23262:SF226 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-7 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000010928.3|UniProtKB=G3R5S6 G3R5S6 HERC6 PTHR45622:SF11 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC6-RELATED ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000024871.2|UniProtKB=G3S9L0 G3S9L0 PAXIP1 PTHR23196:SF48 PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN PAX-INTERACTING PROTEIN 1 positive regulation of transcription by RNA polymerase II#GO:0045944;DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to stress#GO:0033554;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;positive regulation of RNA metabolic process#GO:0051254 intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000023403.2|UniProtKB=A0A2I2ZN48 A0A2I2ZN48 RAD23A PTHR10621:SF29 UV EXCISION REPAIR PROTEIN RAD23 LYSINE-SPECIFIC DEMETHYLASE RAD23A protein-containing complex binding#GO:0044877;protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000027057.2|UniProtKB=G3RY79 G3RY79 TEX47 PTHR34035:SF1 TESTIS-EXPRESSED PROTEIN 47 TESTIS-EXPRESSED PROTEIN 47 GORGO|Ensembl=ENSGGOG00000009838.3|UniProtKB=G3R2Z6 G3R2Z6 HSD17B8 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000011960.3|UniProtKB=G3R8G2 G3R8G2 SLC7A9 PTHR11785:SF354 AMINO ACID TRANSPORTER B(0,+)-TYPE AMINO ACID TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000000833.3|UniProtKB=G3QEW8 G3QEW8 KDM3B PTHR12549:SF8 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3B transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;histone modifying activity#GO:0140993;DNA binding#GO:0003677;histone demethylase activity#GO:0032452;chromatin DNA binding#GO:0031490;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000008922.3|UniProtKB=G3R0N4 G3R0N4 APPBP2 PTHR46575:SF1 AMYLOID PROTEIN-BINDING PROTEIN 2 AMYLOID PROTEIN-BINDING PROTEIN 2 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000004604.3|UniProtKB=G3QPL5 G3QPL5 C5H6orf58 PTHR18820:SF1 LEG1 PROTEIN LEG1 HOMOLOG extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000008988.3|UniProtKB=G3R0U0 G3R0U0 ZNF227 PTHR24381:SF488 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 227 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000042811.1|UniProtKB=A0A2I2ZEG6 A0A2I2ZEG6 PTHR23232:SF67 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 738 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000040023.1|UniProtKB=A0A2I2ZNQ6 A0A2I2ZNQ6 PTHR10927:SF6 RIBOSOME MATURATION PROTEIN SBDS RIBOSOME MATURATION PROTEIN SBDS RNA metabolism protein#PC00031 GORGO|Gene=ZSCAN21|UniProtKB=A1YEV9 A1YEV9 ZSCAN21 PTHR23226:SF10 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 21 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000014884.3|UniProtKB=G3RFZ0 G3RFZ0 ZNF71 PTHR24388:SF119 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 648 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016070.3|UniProtKB=G3RJ08 G3RJ08 RCOR2 PTHR16089:SF12 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 2 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000025446.2|UniProtKB=A0A2I2Y3J9 A0A2I2Y3J9 PTHR48026:SF5 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN RRM DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013311.3|UniProtKB=G3RBW7 G3RBW7 CDK1 PTHR24056:SF334 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;phosphotransferase activity, alcohol group as acceptor#GO:0016773 mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;signal transduction#GO:0007165;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle process#GO:1903047;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Cdc2#P04634 GORGO|Ensembl=ENSGGOG00000011261.3|UniProtKB=G3R6L8 G3R6L8 MMP26 PTHR10201:SF76 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-26 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000001131.3|UniProtKB=G3QFN8 G3QFN8 LOC101128712 PTHR24379:SF97 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 69 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011673.3|UniProtKB=A0A2I2Y7M3 A0A2I2Y7M3 SNX24 PTHR15813:SF10 SORTING NEXIN-22 AND 24 SORTING NEXIN-24 binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000005504.3|UniProtKB=G3QRX5 G3QRX5 DLL1 PTHR24044:SF380 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;negative regulation of Notch signaling pathway#GO:0045746;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;Notch signaling pathway#GO:0007219;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 GORGO|Ensembl=ENSGGOG00000007459.3|UniProtKB=A0A2I2Z7B4 A0A2I2Z7B4 UBE2W PTHR24068:SF153 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 W acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000002292.3|UniProtKB=G3QIP2 G3QIP2 CRYBA1 PTHR11818:SF8 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A3 structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory system development#GO:0048880;multicellular organismal process#GO:0032501 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000002256.3|UniProtKB=G3QIK7 G3QIK7 SLITRK3 PTHR45773:SF6 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 3 regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell junction assembly#GO:1901888;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;neurogenesis#GO:0022008;positive regulation of synapse assembly#GO:0051965;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;positive regulation of nervous system development#GO:0051962;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of cellular component biogenesis#GO:0044089;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;GABA-ergic synapse#GO:0098982 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016665.3|UniProtKB=G3RKJ3 G3RKJ3 TMEM130 PTHR11861:SF10 MELANOCYTE PROTEIN PMEL 17-RELATED TRANSMEMBRANE PROTEIN 130 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000006937.3|UniProtKB=G3QVK8 G3QVK8 EVA1B PTHR48422:SF2 PROTEIN EVA-1 HOMOLOG B-RELATED PROTEIN EVA-1 HOMOLOG B GORGO|Ensembl=ENSGGOG00000015266.3|UniProtKB=G3RGY4 G3RGY4 PLAU PTHR24264:SF38 TRYPSIN-RELATED UROKINASE-TYPE PLASMINOGEN ACTIVATOR catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;regulation of hemostasis#GO:1900046;negative regulation of wound healing#GO:0061045;plasminogen activation#GO:0031639;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of cell adhesion#GO:0030155;negative regulation of response to stimulus#GO:0048585;regulation of coagulation#GO:0050818;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of blood coagulation#GO:0030195;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular process#GO:0050794;regulation of cell adhesion mediated by integrin#GO:0033628;protein metabolic process#GO:0019538;cellular process#GO:0009987;regulation of response to wounding#GO:1903034;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;protein maturation#GO:0051604;gene expression#GO:0010467;regulation of response to external stimulus#GO:0032101;fibrinolysis#GO:0042730;metabolic process#GO:0008152;negative regulation of response to wounding#GO:1903035;regulation of biological process#GO:0050789;zymogen activation#GO:0031638;negative regulation of biological process#GO:0048519;regulation of wound healing#GO:0061041;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;negative regulation of hemostasis#GO:1900047;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;negative regulation of coagulation#GO:0050819 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 Plasminogen activating cascade#P00050>uPA#P01243;CCKR signaling map#P06959>uPA#P07039;CCKR signaling map#P06959>uPA#G06974;CCKR signaling map#P06959>uPA#G07267;Plasminogen activating cascade#P00050>pro-uPA#P01262;Blood coagulation#P00011>uPA#P00424;Blood coagulation#P00011>uPAR#P00433 GORGO|Ensembl=ENSGGOG00000002232.3|UniProtKB=G3QII8 G3QII8 ITM2C PTHR10962:SF5 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2C peptide binding#GO:0042277;binding#GO:0005488 negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000024424.2|UniProtKB=G3S604 G3S604 CBR4 PTHR42760:SF133 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000023241.2|UniProtKB=G3RSQ4 G3RSQ4 BACE2 PTHR47965:SF40 ASPARTYL PROTEASE-RELATED BETA-SECRETASE 2 catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;membrane protein ectodomain proteolysis#GO:0006509;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 protease#PC00190 Alzheimer disease-presenilin pathway#P00004>Pro-BACE-1#P00162;Alzheimer disease-amyloid secretase pathway#P00003>Pro-BACE-1#P00081;Alzheimer disease-presenilin pathway#P00004>BACE-1 pro-domain#P00178;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1 pro-domain#P00094;Alzheimer disease-presenilin pathway#P00004>BACE-1#P00172;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1#P00101 GORGO|Ensembl=ENSGGOG00000014505.3|UniProtKB=G3RF04 G3RF04 XRRA1 PTHR22710:SF2 X-RAY RADIATION RESISTANCE ASSOCIATED PROTEIN 1 XRRA1 X-RAY RADIATION RESISTANCE-ASSOCIATED PROTEIN 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000011620.3|UniProtKB=A0A2I2ZGA7 A0A2I2ZGA7 CAD PTHR11405:SF5 CARBAMOYLTRANSFERASE FAMILY MEMBER MULTIFUNCTIONAL PROTEIN CAD transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity#GO:0016874;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;hydrolase activity#GO:0016787;ligase activity, forming carbon-nitrogen bonds#GO:0016879 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;ligase#PC00142 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 GORGO|Ensembl=ENSGGOG00000009765.3|UniProtKB=G3R2S9 G3R2S9 YIF1A PTHR14083:SF2 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN PROTEIN YIF1A establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 GORGO|Ensembl=ENSGGOG00000007988.3|UniProtKB=A0A2I2YCC6 A0A2I2YCC6 LRRC31 PTHR24109:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 31 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 31 GORGO|Ensembl=ENSGGOG00000042625.1|UniProtKB=A0A2I2Y2J5 A0A2I2Y2J5 PTHR45841:SF2 MRNA TURNOVER PROTEIN 4 MRTO4 MRNA TURNOVER PROTEIN 4 HOMOLOG macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000041925.1|UniProtKB=A0A2I2YNN1 A0A2I2YNN1 PTHR23073:SF74 26S PROTEASOME REGULATORY SUBUNIT AAA+ ATPASE DOMAIN-CONTAINING PROTEIN polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853 regulation of cellular component biogenesis#GO:0044087;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;positive regulation of cellular component organization#GO:0051130;proteasomal protein catabolic process#GO:0010498;positive regulation of cellular component biogenesis#GO:0044089;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;regulation of DNA-templated transcription initiation#GO:2000142;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;ERAD pathway#GO:0036503;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;response to endoplasmic reticulum stress#GO:0034976;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;proteasome complex#GO:0000502;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190 GORGO|Ensembl=ENSGGOG00000005534.3|UniProtKB=G3QS05 G3QS05 ALDH4A1 PTHR14516:SF3 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000008570.3|UniProtKB=G3QZR8 G3QZR8 NRG2 PTHR11100:SF20 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-2, MEMBRANE-BOUND ISOFORM signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intracellular signal transduction#GO:0035556;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;animal organ development#GO:0048513;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;biological regulation#GO:0065007;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 EGF receptor signaling pathway#P00018>EGF#P00549 GORGO|Ensembl=ENSGGOG00000028296.2|UniProtKB=G3S2P5 G3S2P5 GARIN6 PTHR22574:SF11 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 6 GORGO|Ensembl=ENSGGOG00000043858.1|UniProtKB=A0A2I2ZQ35 A0A2I2ZQ35 OR8H1 PTHR48018:SF181 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8H1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000036442.1|UniProtKB=A0A2I2Z2L2 A0A2I2Z2L2 CARF PTHR14694:SF1 CALCIUM-RESPONSIVE TRANSCRIPTION FACTOR CALCIUM-RESPONSIVE TRANSCRIPTION FACTOR DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010482.3|UniProtKB=G3R4L7 G3R4L7 ITFG2 PTHR16317:SF1 INTEGRIN ALPHA REPEAT DOMAIN-CONTAINING KICSTOR COMPLEX PROTEIN ITFG2 regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;negative regulation of TORC1 signaling#GO:1904262;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular response to amino acid starvation#GO:0034198;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to stress#GO:0006950;response to nutrient levels#GO:0031667;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to starvation#GO:0042594 protein-containing complex#GO:0032991 integrin#PC00126 GORGO|Ensembl=ENSGGOG00000036975.1|UniProtKB=A0A2I2ZST7 A0A2I2ZST7 PTHR10553:SF26 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;precatalytic spliceosome#GO:0071011;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526;cytoplasmic ribonucleoprotein granule#GO:0036464;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U12-type spliceosomal complex#GO:0005689;catalytic step 2 spliceosome#GO:0071013;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;ribonucleoprotein granule#GO:0035770;U1 snRNP#GO:0005685;nucleus#GO:0005634;SMN-Sm protein complex#GO:0034719;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;P granule#GO:0043186;U2 snRNP#GO:0005686;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;small nuclear ribonucleoprotein complex#GO:0030532 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000027879.2|UniProtKB=G3S2C4 G3S2C4 PTHR48026:SF6 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN RRM DOMAIN-CONTAINING PROTEIN mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000008550.3|UniProtKB=G3QZP1 G3QZP1 TMEM74 PTHR16125:SF3 TRANSMEMBRANE PROTEIN 74 TRANSMEMBRANE PROTEIN 74 GORGO|Gene=CD209|UniProtKB=Q8HXZ8 Q8HXZ8 CD209 PTHR22802:SF197 C-TYPE LECTIN SUPERFAMILY MEMBER CD209 ANTIGEN monosaccharide binding#GO:0048029;signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;binding#GO:0005488;small molecule binding#GO:0036094 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000010896.3|UniProtKB=G3R5P3 G3R5P3 PTHR33560:SF1 PROTEIN FAM227B PROTEIN FAM227A GORGO|Ensembl=ENSGGOG00000039534.1|UniProtKB=A0A2I2YIB7 A0A2I2YIB7 PTHR19343:SF23 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 1-2 binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000024815.2|UniProtKB=G3S2G4 G3S2G4 BBS12 PTHR46883:SF1 BARDET-BIEDL SYNDROME 12 PROTEIN CHAPERONIN-CONTAINING T-COMPLEX MEMBER BBS12 GORGO|Ensembl=ENSGGOG00000024847.2|UniProtKB=A0A2I2ZBI2 A0A2I2ZBI2 PTHR24071:SF38 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;RNA export from nucleus#GO:0006405;transport#GO:0006810;RNA localization#GO:0006403;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;organelle localization#GO:0051640;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;gene expression#GO:0010467;protein export from nucleus#GO:0006611;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit export from nucleus#GO:0000055;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;protein transport#GO:0015031;protein import into nucleus#GO:0006606;ribosome biogenesis#GO:0042254 nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000028448.2|UniProtKB=G3SFS9 G3SFS9 SF3B2 PTHR12785:SF19 SPLICING FACTOR 3B SPLICING FACTOR 3B SUBUNIT 2 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U2 snRNP#GO:0005686 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000013168.3|UniProtKB=G3RBI8 G3RBI8 TMED8 PTHR22973:SF3 LD35087P PROTEIN TMED8 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000003892.3|UniProtKB=G3SHW4 G3SHW4 MYBL1 PTHR45614:SF9 MYB PROTEIN-RELATED MYB-RELATED PROTEIN A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 cell cycle#GO:0007049;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;mitotic cell cycle#GO:0000278;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000014127.3|UniProtKB=G3RE14 G3RE14 SNRK PTHR24346:SF90 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SNF-RELATED SERINE_THREONINE-PROTEIN KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009204.3|UniProtKB=G3R1D2 G3R1D2 INCA1 PTHR37341:SF1 PROTEIN INCA1 PROTEIN INCA1 enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;cyclin binding#GO:0030332 regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;negative regulation of cell population proliferation#GO:0008285;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007832.3|UniProtKB=G3QXU4 G3QXU4 AHSA1 PTHR13009:SF7 HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1 ACTIVATOR OF 90 KDA HEAT SHOCK PROTEIN ATPASE HOMOLOG 1 ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000012427.3|UniProtKB=G3R9P8 G3R9P8 STK10 PTHR46538:SF2 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE GORGO|Ensembl=ENSGGOG00000013494.3|UniProtKB=A0A2I2Z398 A0A2I2Z398 POLR1B PTHR20856:SF5 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA2 catalytic activity, acting on RNA#GO:0140098;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 GORGO|Ensembl=ENSGGOG00000039726.1|UniProtKB=A0A2I2ZJA4 A0A2I2ZJA4 OR2L5 PTHR26453:SF166 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2L5 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006675.3|UniProtKB=G3QUW7 G3QUW7 TICAM1 PTHR47230:SF1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 positive regulation of response to external stimulus#GO:0032103;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;immune response-regulating signaling pathway#GO:0002764;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;toll-like receptor signaling pathway#GO:0002224;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;pattern recognition receptor signaling pathway#GO:0002221;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;positive regulation of response to biotic stimulus#GO:0002833;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of type I interferon production#GO:0032481;innate immune response-activating signaling pathway#GO:0002758;positive regulation of signal transduction#GO:0009967;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TRIF#P01344 GORGO|Ensembl=ENSGGOG00000015025.3|UniProtKB=G3RGC7 G3RGC7 MPP4 PTHR23122:SF34 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 4 cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000041716.1|UniProtKB=A0A2I2Z0G1 A0A2I2Z0G1 PTHR48026:SF10 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN RRM DOMAIN-CONTAINING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000007753.3|UniProtKB=G3QXM9 G3QXM9 TMED6 PTHR22811:SF45 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000011514.3|UniProtKB=G3R7A2 G3R7A2 PLBD1 PTHR12370:SF1 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE LYSOSOMAL LEUCINE AMINOPEPTIDASE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000011890.3|UniProtKB=G3R897 G3R897 DAG1 PTHR21559:SF22 DYSTROGLYCAN-RELATED DYSTROGLYCAN 1 protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;cell projection morphogenesis#GO:0048858;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;system development#GO:0048731;axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelium development#GO:0060429;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485 extracellular region#GO:0005576;basement membrane#GO:0005604;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;sarcolemma#GO:0042383;cell periphery#GO:0071944;external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012;dystrophin-associated glycoprotein complex#GO:0016010;plasma membrane#GO:0005886;protein-containing complex#GO:0032991 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000039991.1|UniProtKB=A0A2I2ZK86 A0A2I2ZK86 PTHR24068:SF323 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;response to stress#GO:0006950;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Toll receptor signaling pathway#P00054>Uev1A#P01376 GORGO|Ensembl=ENSGGOG00000012109.3|UniProtKB=G3R8U8 G3R8U8 LOC101153734 PTHR12184:SF1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex III assembly#GO:0034551;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Gene=1C01_GORGO|UniProtKB=P30383 P30383 PTHR16675:SF294 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, C ALPHA CHAIN protein binding#GO:0005515;peptide binding#GO:0042277;antigen binding#GO:0003823;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008960.3|UniProtKB=G3R0R8 G3R0R8 SULT1E1 PTHR11783:SF53 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1E1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000012724.3|UniProtKB=G3RAE0 G3RAE0 BOLA2B PTHR12735:SF42 BOLA-LIKE PROTEIN-RELATED BOLA-LIKE PROTEIN 2 iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094 homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000007746.3|UniProtKB=G3QXM5 G3QXM5 F2RL3 PTHR24232:SF22 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 4 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Blood coagulation#P00011>PAR-4#P00461 GORGO|Ensembl=ENSGGOG00000011571.3|UniProtKB=G3R7F2 G3R7F2 ROR2 PTHR24416:SF132 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR2 transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;Wnt-protein binding#GO:0017147;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;signaling receptor complex#GO:0043235;axon#GO:0030424 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012437.3|UniProtKB=G3S785 G3S785 IRGC PTHR32341:SF10 INTERFERON-INDUCIBLE GTPASE INTERFERON-INDUCIBLE GTPASE 5 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 GORGO|Ensembl=ENSGGOG00000011497.3|UniProtKB=G3S227 G3S227 SLC37A3 PTHR43184:SF33 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B SUGAR PHOSPHATE EXCHANGER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;xenobiotic transmembrane transporter activity#GO:0042910 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000003161.3|UniProtKB=G3QKX2 G3QKX2 ITGA7 PTHR23220:SF90 INTEGRIN ALPHA INTEGRIN ALPHA-7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;leukocyte migration#GO:0050900;biological regulation#GO:0065007;cell migration#GO:0016477;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;integrin-mediated signaling pathway#GO:0007229 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000006525.3|UniProtKB=G3QUI5 G3QUI5 PTHR11036:SF80 SEMAPHORIN SEMAPHORIN-7A integrin binding#GO:0005178;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cell adhesion molecule binding#GO:0050839;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;chemotaxis#GO:0006935;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;axon guidance#GO:0007411;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stress#GO:0080134;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;integrin-mediated signaling pathway#GO:0007229;positive regulation of cell motility#GO:2000147;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 membrane-bound signaling molecule#PC00152 GORGO|Ensembl=ENSGGOG00000002089.3|UniProtKB=G3RW59 G3RW59 DOK5 PTHR21258:SF45 DOCKING PROTEIN RELATED DOCKING PROTEIN 5 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003613.3|UniProtKB=A0A2I2ZFY1 A0A2I2ZFY1 WNT2B PTHR12027:SF93 WNT RELATED PROTEIN WNT-2B signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 GORGO|Ensembl=ENSGGOG00000003260.3|UniProtKB=G3QL61 G3QL61 GZMM PTHR24271:SF51 KALLIKREIN-RELATED GRANZYME M serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000024692.2|UniProtKB=G3S168 G3S168 PTHR10836:SF87 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity#GO:0016491 pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000005563.3|UniProtKB=A0A2I2YQ79 A0A2I2YQ79 U2SURP PTHR23140:SF0 RNA PROCESSING PROTEIN LD23810P U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000000150.3|UniProtKB=G3QD45 G3QD45 SLC25A28 PTHR45758:SF20 MITOFERRIN-1-RELATED MITOFERRIN-2 transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;iron ion transmembrane transporter activity#GO:0005381;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;iron ion transmembrane transport#GO:0034755;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000012908.3|UniProtKB=G3RAV6 G3RAV6 GP9 PTHR22650:SF6 GLYCOPROTEIN IB BETA PLATELET GLYCOPROTEIN IX Blood coagulation#P00011>GP IX#P00455 GORGO|Ensembl=ENSGGOG00000000259.3|UniProtKB=G3QDE2 G3QDE2 LOC101127866 PTHR46985:SF4 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 8 endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504;signaling receptor activity#GO:0038023;molecular function regulator activity#GO:0098772 defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;apoptotic signaling pathway#GO:0097190;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of defense response#GO:0031347;inflammatory response#GO:0006954;regulation of immune response#GO:0050776;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;intrinsic apoptotic signaling pathway#GO:0097193;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;apoptotic process#GO:0006915;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;canonical inflammasome complex#GO:0061702;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000012981.3|UniProtKB=G3RB26 G3RB26 AGRP PTHR16551:SF4 AGOUTI RELATED AGOUTI-RELATED PROTEIN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;G protein-coupled receptor binding#GO:0001664;neuropeptide hormone activity#GO:0005184;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 feeding behavior#GO:0007631;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000041367.1|UniProtKB=A0A2I2Y5U3 A0A2I2Y5U3 PTHR28664:SF5 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 DOMAIN-CONTAINING PROTEIN endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus subcompartment#GO:0098791 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000024610.2|UniProtKB=G3SIQ1 G3SIQ1 DNAJB1 PTHR24078:SF568 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 1 protein binding#GO:0005515;binding#GO:0005488;transcription regulator activity#GO:0140110;Hsp70 protein binding#GO:0030544;protein-folding chaperone binding#GO:0051087;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;heat shock protein binding#GO:0031072 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;metabolic process#GO:0008152;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;gene expression#GO:0010467;protein maturation#GO:0051604;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;protein folding#GO:0006457;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000023012.2|UniProtKB=G3S8K6 G3S8K6 LOC101132611 PTHR26452:SF176 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5A2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025024.2|UniProtKB=G3RR08 G3RR08 PTHR10369:SF6 60S RIBOSOMAL PROTEIN L36A/L44 LARGE RIBOSOMAL SUBUNIT PROTEIN EL42 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013056.3|UniProtKB=G3RBB0 G3RBB0 CIT PTHR22988:SF71 MYOTONIC DYSTROPHY S/T KINASE-RELATED CITRON RHO-INTERACTING KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 organelle organization#GO:0006996;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell cycle#GO:0007049;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actomyosin structure organization#GO:0031032;actin filament-based process#GO:0030029;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000025968.2|UniProtKB=A0A2I2Z5N5 A0A2I2Z5N5 LOC101127117 PTHR14519:SF8 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 biological regulation#GO:0065007;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;regulation of body fluid levels#GO:0050878;coagulation#GO:0050817;cellular process#GO:0009987;response to stress#GO:0006950;response to wounding#GO:0009611;ketone metabolic process#GO:0042180;vitamin K metabolic process#GO:0042373;hemostasis#GO:0007599;wound healing#GO:0042060;blood coagulation#GO:0007596;regulation of biological quality#GO:0065008;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000023808.2|UniProtKB=G3RW61 G3RW61 STX1B PTHR19957:SF334 SYNTAXIN SYNTAXIN-1B SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;exocytosis#GO:0006887;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;protein transport#GO:0015031;secretion by cell#GO:0032940;export from cell#GO:0140352;vesicle fusion#GO:0006906;cellular component organization#GO:0016043 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 GORGO|Ensembl=ENSGGOG00000006497.3|UniProtKB=G3QUF4 G3QUF4 PTHR10306:SF9 SYNAPTOPHYSIN SYNAPTOPHYSIN-LIKE PROTEIN 1 cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;presynapse#GO:0098793;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000015794.3|UniProtKB=G3RIA5 G3RIA5 CHST4 PTHR10704:SF40 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;amino sugar metabolic process#GO:0006040 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000014084.3|UniProtKB=G3RDX7 G3RDX7 ZSCAN5B PTHR23226:SF306 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005034.3|UniProtKB=G3SDW7 G3SDW7 ST3GAL4 PTHR13713:SF57 SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 4 sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000012043.3|UniProtKB=G3S238 G3S238 GIPC1 PTHR12259:SF4 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC1 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027164.2|UniProtKB=G3S2A5 G3S2A5 HMGB3 PTHR48112:SF43 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B3 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000016059.3|UniProtKB=G3RIZ4 G3RIZ4 XK PTHR14297:SF8 MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER ENDOPLASMIC RETICULUM MEMBRANE ADAPTER PROTEIN XK protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000044014.1|UniProtKB=A0A2I2YJS3 A0A2I2YJS3 NR2C2 PTHR24083:SF48 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 2 sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 CCKR signaling map#P06959>TAK1#P07170 GORGO|Ensembl=ENSGGOG00000017136.3|UniProtKB=G3RLR0 G3RLR0 CASP8AP2 PTHR15489:SF2 CASPASE 8 ASSOCIATED PROTEIN 2 CASP8-ASSOCIATED PROTEIN 2 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;apoptotic signaling pathway#GO:0097190;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;cell death#GO:0008219 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear body#GO:0016604 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000006295.3|UniProtKB=G3RZC7 G3RZC7 YIPF5 PTHR21236:SF6 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF5 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;vesicle fusion#GO:0006906;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;Golgi organization#GO:0007030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of localization#GO:0032879;regulation of transport#GO:0051049;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000005291.3|UniProtKB=G3RRH1 G3RRH1 PTHLH PTHR17223:SF0 PARATHYROID HORMONE-RELATED PARATHYROID HORMONE-RELATED PROTEIN hormone receptor binding#GO:0051427;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 anatomical structure development#GO:0048856;skeletal system development#GO:0001501;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;osteoblast differentiation#GO:0001649;regulation of cellular process#GO:0050794;ossification#GO:0001503;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;regulation of developmental process#GO:0050793;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell differentiation#GO:0045595;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000039286.1|UniProtKB=A0A2I2YP39 A0A2I2YP39 PTHR35248:SF2 PUTATIVE-RELATED SURFACE ANTIGEN BSPA-LIKE GORGO|Ensembl=ENSGGOG00000009646.3|UniProtKB=G3R2H0 G3R2H0 PTHR13551:SF1 BRAIN PROTEIN I3 MEMBRANE PROTEIN BRI3 GORGO|Ensembl=ENSGGOG00000000062.3|UniProtKB=G3QCW4 G3QCW4 UBR4 PTHR21725:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR4 E3 UBIQUITIN-PROTEIN LIGASE UBR4 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000043367.1|UniProtKB=A0A2I2Z5T6 A0A2I2Z5T6 TCEAL8 PTHR48555:SF1 TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 8-RELATED TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 8 GORGO|Ensembl=ENSGGOG00000000581.3|UniProtKB=G3QE81 G3QE81 CORO6 PTHR10856:SF23 CORONIN CORONIN-6 actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;cell motility#GO:0048870 cytoskeleton#GO:0005856;actin filament#GO:0005884;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;supramolecular complex#GO:0099080;lamellipodium#GO:0030027;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000010900.3|UniProtKB=G3R5N8 G3R5N8 DEFA4 PTHR11876:SF23 ALPHA-DEFENSIN 1 DEFENSIN ALPHA 4 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000043115.1|UniProtKB=A0A2I2ZD99 A0A2I2ZD99 OR8G5 PTHR48018:SF48 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8G5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000001956.3|UniProtKB=G3QHU1 G3QHU1 SLC9A8 PTHR10110:SF191 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 8 sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000009051.3|UniProtKB=G3R101 G3R101 ADPRM PTHR16509:SF1 FAMILY NOT NAMED MANGANESE-DEPENDENT ADP-RIBOSE_CDP-ALCOHOL DIPHOSPHATASE cation binding#GO:0043169;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on ester bonds#GO:0016788;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 GORGO|Ensembl=ENSGGOG00000001887.3|UniProtKB=G3QHM6 G3QHM6 APOD PTHR10612:SF65 APOLIPOPROTEIN D APOLIPOPROTEIN D sterol binding#GO:0032934;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;cholesterol binding#GO:0015485;steroid binding#GO:0005496;alcohol binding#GO:0043178 response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;response to oxygen-containing compound#GO:1901700;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000005799.3|UniProtKB=G3QSN3 G3QSN3 MRPL34 PTHR14503:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000273.3|UniProtKB=G3QDF2 G3QDF2 TRPV2 PTHR10582:SF5 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 2 calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014003.3|UniProtKB=A0A2I2YPG5 A0A2I2YPG5 CHTF18 PTHR23389:SF33 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000008697.3|UniProtKB=G3R038 G3R038 OVCH1 PTHR24251:SF21 OVOCHYMASE-RELATED OVOCHYMASE-1 serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000007462.3|UniProtKB=G3QWX9 G3QWX9 ENPP4 PTHR10151:SF79 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE ENPP4 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000013037.3|UniProtKB=G3RB79 G3RB79 MIOX PTHR12588:SF0 MYOINOSITOL OXYGENASE INOSITOL OXYGENASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000008991.3|UniProtKB=G3R0V2 G3R0V2 ATP8B3 PTHR24092:SF78 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IK molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;phospholipid transport#GO:0015914;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000026469.2|UniProtKB=G3S660 G3S660 CCDC71 PTHR14484:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 GORGO|Ensembl=ENSGGOG00000025716.2|UniProtKB=G3S4E1 G3S4E1 SET PTHR11875:SF67 TESTIS-SPECIFIC Y-ENCODED PROTEIN PROTEIN SET protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000023056.2|UniProtKB=A0A2I2ZGE3 A0A2I2ZGE3 PTHR11710:SF15 40S RIBOSOMAL PROTEIN S19 SMALL RIBOSOMAL SUBUNIT PROTEIN ES19 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011966.3|UniProtKB=G3R8G0 G3R8G0 POU1F1 PTHR11636:SF84 POU DOMAIN PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000040715.1|UniProtKB=G3QHV7 G3QHV7 LOC101123789 PTHR26453:SF183 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AG1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000646.3|UniProtKB=G3QEE5 G3QEE5 CARMIL1 PTHR24112:SF39 LEUCINE-RICH REPEAT, ISOFORM F-RELATED F-ACTIN-UNCAPPING PROTEIN LRRC16A regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of actin filament organization#GO:0110053;regulation of organelle organization#GO:0033043;cellular process#GO:0009987;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;cell migration#GO:0016477;cell motility#GO:0048870;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970 lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000013315.3|UniProtKB=G3SK33 G3SK33 LOC101152881 PTHR24291:SF220 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F3 lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;arachidonate metabolic process#GO:0019369;vitamin K metabolic process#GO:0042373;ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000010340.3|UniProtKB=G3R495 G3R495 FGFRL1 PTHR19890:SF13 FIBROBLAST GROWTH FACTOR RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR-LIKE 1 molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;fibroblast growth factor binding#GO:0017134;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 tyrosine protein kinase receptor#PC00233;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012865.3|UniProtKB=G3RAS4 G3RAS4 PROSC PTHR10146:SF18 PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;heterocyclic compound binding#GO:1901363 pyridine-containing compound metabolic process#GO:0072524;cellular process#GO:0009987;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000024647.2|UniProtKB=G3S745 G3S745 GLIPR1L2 PTHR10334:SF236 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIPR1-LIKE PROTEIN 2 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000004586.3|UniProtKB=G3QPJ5 G3QPJ5 CCNB1IP1 PTHR14305:SF0 E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;homologous recombination#GO:0035825;reproductive process#GO:0022414;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;cell cycle#GO:0007049;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;organelle fission#GO:0048285;sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280 condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000041919.1|UniProtKB=A0A2I2ZC67 A0A2I2ZC67 GJA5 PTHR11984:SF13 CONNEXIN GAP JUNCTION ALPHA-5 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 multicellular organismal process#GO:0032501;heart development#GO:0007507;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular process#GO:0009987;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of system process#GO:0044057;developmental process#GO:0032502;circulatory system development#GO:0072359;regulation of heart contraction#GO:0008016;signaling#GO:0023052;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108 cell junction#GO:0030054;anchoring junction#GO:0070161;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 gap junction#PC00105;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000028044.2|UniProtKB=G3S1Z1 G3S1Z1 TMA7 PTHR28632:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 GORGO|Ensembl=ENSGGOG00000001446.3|UniProtKB=G3QGH0 G3QGH0 CA11 PTHR18952:SF93 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN 11 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 GORGO|Ensembl=ENSGGOG00000039210.1|UniProtKB=A0A2I2YGU8 A0A2I2YGU8 PTHR24031:SF634 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX18 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000024436.2|UniProtKB=A0A2I2Z1U9 A0A2I2Z1U9 METTL6 PTHR22809:SF5 METHYLTRANSFERASE-RELATED TRNA N(3)-CYTIDINE METHYLTRANSFERASE METTL6 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000024995.2|UniProtKB=G3RXN3 G3RXN3 GPR65 PTHR24232:SF49 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 65 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000003098.3|UniProtKB=G3QKR9 G3QKR9 ALS2CL PTHR46089:SF1 ALSIN HOMOLOG ALS2 C-TERMINAL-LIKE PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GORGO|Ensembl=ENSGGOG00000007397.3|UniProtKB=G3QWS3 G3QWS3 CHPT1 PTHR10414:SF32 ETHANOLAMINEPHOSPHOTRANSFERASE CHOLINEPHOSPHOTRANSFERASE 1 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000004623.3|UniProtKB=A0A2I2ZVE9 A0A2I2ZVE9 TRPV4 PTHR10582:SF4 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;import across plasma membrane#GO:0098739;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;cellular component organization#GO:0016043;response to abiotic stimulus#GO:0009628;calcium ion transport#GO:0006816;cellular response to chemical stress#GO:0062197;cellular component organization or biogenesis#GO:0071840;calcium ion transmembrane import into cytosol#GO:0097553;import into cell#GO:0098657;cellular response to abiotic stimulus#GO:0071214;monoatomic cation transmembrane transport#GO:0098655;cytoskeleton organization#GO:0007010;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;actin filament-based process#GO:0030029;cellular response to osmotic stress#GO:0071470;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;cellular response to environmental stimulus#GO:0104004;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;calcium ion import#GO:0070509;osmosensory signaling pathway#GO:0007231;cellular response to stimulus#GO:0051716;actin filament organization#GO:0007015;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;response to osmotic stress#GO:0006970;transport#GO:0006810;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220 membrane-bounded organelle#GO:0043227;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 GORGO|Gene=1B04_GORGO|UniProtKB=P30382 P30382 PTHR16675:SF270 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B ALPHA CHAIN protein binding#GO:0005515;peptide binding#GO:0042277;antigen binding#GO:0003823;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000028378.2|UniProtKB=G3RZ21 G3RZ21 PTHR19367:SF39 T-CELL RECEPTOR ALPHA CHAIN V REGION IG-LIKE DOMAIN-CONTAINING PROTEIN adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000036986.1|UniProtKB=A0A2I2YD81 A0A2I2YD81 LOC101126997 PTHR24028:SF139 CADHERIN-87A PROTOCADHERIN BETA-14 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 GORGO|Ensembl=ENSGGOG00000034959.2|UniProtKB=G3SKS9 G3SKS9 GALNT13 PTHR11675:SF47 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 13 glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000015046.3|UniProtKB=G3SK16 G3SK16 DNAJC9 PTHR44144:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000004220.3|UniProtKB=G3SGZ9 G3SGZ9 NPLOC4 PTHR12710:SF0 NUCLEAR PROTEIN LOCALIZATION 4 NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 GORGO|Ensembl=ENSGGOG00000008653.3|UniProtKB=G3QZY6 G3QZY6 GMEB2 PTHR10417:SF2 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 2 transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000039239.1|UniProtKB=A0A2I2ZH89 A0A2I2ZH89 H2AZ2 PTHR23430:SF280 HISTONE H2A HISTONE H2A.V structural molecule activity#GO:0005198 regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000015789.3|UniProtKB=G3RW67 G3RW67 PTHR26450:SF175 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E6 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016487.3|UniProtKB=A0A2I2YC73 A0A2I2YC73 METTL25B PTHR12496:SF2 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25B RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000009004.3|UniProtKB=G3R0V7 G3R0V7 ZC3H8 PTHR13119:SF32 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 8 transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity#GO:0001217 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of DNA-templated transcription elongation#GO:0032784 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000010550.3|UniProtKB=A0A2I2YYD7 A0A2I2YYD7 TM9SF4 PTHR10766:SF188 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 4 localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;localization within membrane#GO:0051668;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000040938.1|UniProtKB=A0A2I2Z2M3 A0A2I2Z2M3 OTUD5 PTHR12419:SF122 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 5 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843 regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of TORC1 signaling#GO:1904263;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000010435.3|UniProtKB=G3R4H6 G3R4H6 CRABP1 PTHR11955:SF62 FATTY ACID BINDING PROTEIN CELLULAR RETINOIC ACID-BINDING PROTEIN 1 organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;binding#GO:0005488;lipid binding#GO:0008289;fatty acid binding#GO:0005504 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000043731.1|UniProtKB=A0A2I2YDC0 A0A2I2YDC0 CLN8 PTHR13439:SF7 CT120 PROTEIN PROTEIN CLN8 lipid binding#GO:0008289;binding#GO:0005488 system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;multicellular organism development#GO:0007275;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;developmental process#GO:0032502;metabolic process#GO:0008152;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000001344.3|UniProtKB=G3QG77 G3QG77 SLC38A2 PTHR22950:SF207 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID SYMPORTER 2 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175 amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 amino acid transporter#PC00046;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000016658.3|UniProtKB=A0A2I2Y604 A0A2I2Y604 CIBAR2 PTHR21223:SF3 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 2 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary basal body#GO:0036064;ciliary transition zone#GO:0035869;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 GORGO|Ensembl=ENSGGOG00000010641.3|UniProtKB=A0A2I2Y6M6 A0A2I2Y6M6 ZNF358 PTHR24393:SF92 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 358 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000039200.1|UniProtKB=A0A2I2Z9Q3 A0A2I2Z9Q3 IFT80 PTHR24098:SF11 OUTER SEGMENT 5 INTRAFLAGELLAR TRANSPORT PROTEIN 80 HOMOLOG organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intraciliary transport particle B#GO:0030992;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 GORGO|Ensembl=ENSGGOG00000041450.1|UniProtKB=A0A2I2Y7Q1 A0A2I2Y7Q1 ZNF621 PTHR24390:SF276 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZFP2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000010687.3|UniProtKB=G3R566 G3R566 GEMIN5 PTHR46362:SF1 GEM-ASSOCIATED PROTEIN 5 GEM-ASSOCIATED PROTEIN 5 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397 Sm-like protein family complex#GO:0120114;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000002791.3|UniProtKB=G3QJY8 G3QJY8 PIR PTHR13903:SF33 PIRIN-RELATED PIRIN oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular process#GO:0009987;mononuclear cell differentiation#GO:1903131;leukocyte differentiation#GO:0002521;cell development#GO:0048468;hemopoiesis#GO:0030097;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000024508.2|UniProtKB=G3RXB8 G3RXB8 KLHL20 PTHR24412:SF508 KELCH PROTEIN KELCH-LIKE PROTEIN 20 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;proteasomal protein catabolic process#GO:0010498;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;macromolecule catabolic process#GO:0009057;intracellular transport#GO:0046907;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;Golgi to endosome transport#GO:0006895;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cytosolic transport#GO:0016482;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;protein metabolic process#GO:0019538;localization#GO:0051179 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;Golgi apparatus subcompartment#GO:0098791;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;membraneless organelle#GO:0043228;transferase complex#GO:1990234;Golgi apparatus#GO:0005794 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006263.3|UniProtKB=A0A2I2YH54 A0A2I2YH54 SLC8A3 PTHR11878:SF7 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 3 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;export from cell#GO:0140352;homeostatic process#GO:0042592;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801 axon#GO:0030424;sarcolemma#GO:0042383;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000014699.3|UniProtKB=G3RFH2 G3RFH2 LOC101133657 PTHR24379:SF6 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 442 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000011556.3|UniProtKB=G3R7D3 G3R7D3 LOC101139234 PTHR34446:SF4 SMALL INTEGRAL MEMBRANE PROTEIN 10 SMALL INTEGRAL MEMBRANE PROTEIN 10 GORGO|Ensembl=ENSGGOG00000005026.3|UniProtKB=G3QQQ3 G3QQQ3 WRAP53 PTHR13211:SF1 TELOMERASE CAJAL BODY PROTEIN 1 TELOMERASE CAJAL BODY PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 GORGO|Ensembl=ENSGGOG00000027932.2|UniProtKB=A0A2I2Z6J6 A0A2I2Z6J6 PTHR24056:SF392 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 7 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;regulation of cellular process#GO:0050794;DNA-templated transcription initiation#GO:0006352;regulation of cell cycle#GO:0051726;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000011390.3|UniProtKB=G3R6Y3 G3R6Y3 HEMGN PTHR15993:SF6 HEMOGEN HEMOGEN biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000007015.3|UniProtKB=G3SGX1 G3SGX1 PTHR20837:SF2 CENTROSOMAL PROTEIN-RELATED PROTEIN CC2D2B cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;localization#GO:0051179;organelle assembly#GO:0070925;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036 ciliary transition zone#GO:0035869;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000037963.1|UniProtKB=A0A2I2YW57 A0A2I2YW57 PTHR19367:SF9 T-CELL RECEPTOR ALPHA CHAIN V REGION IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN immune response#GO:0006955;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000004216.3|UniProtKB=G3QNM1 G3QNM1 CREB3L2 PTHR46004:SF2 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383 GORGO|Ensembl=ENSGGOG00000005975.3|UniProtKB=G3QT39 G3QT39 AOPEP PTHR46627:SF1 AMINOPEPTIDASE O AMINOPEPTIDASE O membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 protease#PC00190 GORGO|Ensembl=ENSGGOG00000006431.3|UniProtKB=A0A2I2YGZ5 A0A2I2YGZ5 MAP1LC3A PTHR10969:SF14 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 ALPHA microtubule binding#GO:0008017;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;ubiquitin protein ligase binding#GO:0031625 mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;cellular response to nutrient levels#GO:0031669;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;cellular response to stress#GO:0033554;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716 membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;vacuolar membrane#GO:0005774 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000014816.3|UniProtKB=G3RS86 G3RS86 CHD9 PTHR46850:SF1 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 ATP-DEPENDENT CHROMATIN REMODELER CHD9 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000041586.1|UniProtKB=G3QZJ5 G3QZJ5 SNRNP25 PTHR14942:SF21 U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 GORGO|Ensembl=ENSGGOG00000041876.1|UniProtKB=A0A2I2YL74 A0A2I2YL74 PTHR31728:SF3 ABRAXAS FAMILY MEMBER COILED-COIL DOMAIN-CONTAINING PROTEIN 98 protein binding#GO:0005515;microtubule binding#GO:0008017;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;organelle assembly#GO:0070925;organelle localization#GO:0051640;localization#GO:0051179;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;attachment of spindle microtubules to kinetochore#GO:0008608;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000010930.3|UniProtKB=G3R5R8 G3R5R8 CHIC1 PTHR13005:SF2 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000008481.3|UniProtKB=G3QZI2 G3QZI2 CLINT1 PTHR12276:SF126 EPSIN/ENT-RELATED CLATHRIN INTERACTOR 1 phospholipid binding#GO:0005543;binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515;lipid binding#GO:0008289 protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 cytoplasm#GO:0005737;vesicle coat#GO:0030120;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000008963.3|UniProtKB=A0A2I2YJV0 A0A2I2YJV0 NEU1 PTHR10628:SF25 SIALIDASE SIALIDASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;ceramide metabolic process#GO:0006672;carbohydrate catabolic process#GO:0016052 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosome#GO:0005764 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000013427.3|UniProtKB=G3RC79 G3RC79 AKAP8 PTHR12190:SF6 A-KINASE ANCHOR PROTEIN AKAP 8 A-KINASE ANCHOR PROTEIN 8 protein binding#GO:0005515;protein kinase A regulatory subunit binding#GO:0034237;binding#GO:0005488;protein kinase A binding#GO:0051018 mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;organelle fission#GO:0048285;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006293.3|UniProtKB=G3S176 G3S176 SRF PTHR48019:SF168 SERUM RESPONSE FACTOR HOMOLOG SERUM RESPONSE FACTOR transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;MADS box transcription factor#PC00250 PDGF signaling pathway#P00047>SRF#P01165;CCKR signaling map#P06959>SRF#P07181;PDGF signaling pathway#P00047>c-fos#P01145;Interleukin signaling pathway#P00036>SRF#P00987;Ras Pathway#P04393>SRF#P04561;p38 MAPK pathway#P05918>SRF#P06025;Gonadotropin-releasing hormone receptor pathway#P06664>SRF#P06811 GORGO|Ensembl=ENSGGOG00000007662.3|UniProtKB=G3QXF1 G3QXF1 TRIM38 PTHR24103:SF47 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM38 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000025527.2|UniProtKB=G3SF02 G3SF02 ADGRG4 PTHR12011:SF277 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G4 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000000146.3|UniProtKB=G3QD41 G3QD41 IGSF5 PTHR44991:SF1 IMMUNOGLOBULIN SUPERFAMILY MEMBER 5 IMMUNOGLOBULIN SUPERFAMILY MEMBER 5 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell surface#GO:0009986;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296 immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000012817.4|UniProtKB=G3RAN0 G3RAN0 DCP1A PTHR16290:SF4 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 MRNA-DECAPPING ENZYME 1A RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629 cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;mRNA capping factor#PC00145 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 GORGO|Ensembl=ENSGGOG00000023842.2|UniProtKB=G3SBE9 G3SBE9 P4HB PTHR18929:SF101 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;external side of plasma membrane#GO:0009897;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000037743.1|UniProtKB=G3S9U2 G3S9U2 PTHR11736:SF17 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN C1 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006501.3|UniProtKB=G3QUG0 G3QUG0 LOC101123970 PTHR20973:SF0 NON-SMC ELEMENT 1-RELATED NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;condensed chromosome#GO:0000793;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000015786.3|UniProtKB=A0A2I2ZTJ4 A0A2I2ZTJ4 ADCY8 PTHR45627:SF1 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 8 lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975 cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 GORGO|Ensembl=ENSGGOG00000041240.1|UniProtKB=A0A2I2ZJV0 A0A2I2ZJV0 BNIP3L PTHR15186:SF3 RE48077P BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3-LIKE regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;process utilizing autophagic mechanism#GO:0061919;organelle organization#GO:0006996;autophagy#GO:0006914;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;macroautophagy#GO:0016236;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;regulation of apoptotic process#GO:0042981;mitophagy#GO:0000423;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;nuclear envelope#GO:0005635 GORGO|Ensembl=ENSGGOG00000010757.3|UniProtKB=G3R5C5 G3R5C5 PTHR10881:SF63 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8B endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi stack#GO:0005795;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi cis cisterna#GO:0000137;cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cis-Golgi network#GO:0005801;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000042328.1|UniProtKB=A0A2I2ZQ97 A0A2I2ZQ97 ZNF678 PTHR24381:SF367 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 678 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000011104.3|UniProtKB=G3SCZ3 G3SCZ3 ARHGAP23 PTHR23175:SF5 PDZ DOMAIN-CONTAINING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 23 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 GORGO|Ensembl=ENSGGOG00000010599.3|UniProtKB=G3R4W9 G3R4W9 G6PC3 PTHR12591:SF2 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE 3 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate biosynthetic process#GO:0016051;small molecule metabolic process#GO:0044281;hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;glucose metabolic process#GO:0006006;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000011722.3|UniProtKB=A0A2I2ZBG7 A0A2I2ZBG7 HNRNPUL2 PTHR12381:SF66 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000000866.3|UniProtKB=A0A2I2ZYU1 A0A2I2ZYU1 LEFTY2 PTHR11848:SF232 TGF-BETA FAMILY LEFT-RIGHT DETERMINATION FACTOR 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 multicellular organism development#GO:0007275;anterior/posterior axis specification#GO:0009948;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;anterior/posterior pattern specification#GO:0009952;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to growth factor stimulus#GO:0071363;pattern specification process#GO:0007389;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000001519.3|UniProtKB=A0A2I2YW86 A0A2I2YW86 TMX2 PTHR15853:SF2 THIOREDOXIN-RELATED THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;brain development#GO:0007420;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;head development#GO:0060322 membrane#GO:0016020;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;organelle membrane contact site#GO:0044232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000015877.3|UniProtKB=A0A2I2Z916 A0A2I2Z916 DESI1 PTHR12378:SF7 DESUMOYLATING ISOPEPTIDASE DESUMOYLATING ISOPEPTIDASE 1 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;protein transport#GO:0015031;regulation of protein catabolic process#GO:0042176;nuclear transport#GO:0051169;cellular localization#GO:0051641;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000043075.1|UniProtKB=A0A2I2ZUQ0 A0A2I2ZUQ0 FAM210B PTHR21377:SF16 PROTEIN FAM210B, MITOCHONDRIAL MITOCHONDRIAL INNER MEMBRANE SCAFFOLD 2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000013249.3|UniProtKB=G3RBQ7 G3RBQ7 PRR19 PTHR37346:SF1 PROLINE-RICH PROTEIN 19 PROLINE-RICH PROTEIN 19 GORGO|Ensembl=ENSGGOG00000008496.3|UniProtKB=G3QZJ3 G3QZJ3 SPATA18 PTHR21771:SF0 MITOCHONDRIA-EATING PROTEIN-RELATED MITOCHONDRIA-EATING PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;molecular condensate scaffold activity#GO:0140693 autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mitochondrion organization#GO:0007005;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;macromolecule catabolic process#GO:0009057;process utilizing autophagic mechanism#GO:0061919;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538 mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000028438.2|UniProtKB=A0A2I2YUS6 A0A2I2YUS6 TMEM40 PTHR16108:SF2 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 40 GORGO|Ensembl=ENSGGOG00000015633.3|UniProtKB=G3RHW9 G3RHW9 LOC101149201 PTHR24242:SF402 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR FAMILY 6 SUBFAMILY K MEMBER 3 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000011265.3|UniProtKB=G3R6M3 G3R6M3 HINT2 PTHR23089:SF18 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 nucleotide phosphatase#PC00173 GORGO|Ensembl=ENSGGOG00000009108.3|UniProtKB=A0A2I2YDH8 A0A2I2YDH8 GPLD1 PTHR23221:SF7 GLYCOSYLPHOSPHATIDYLINOSITOL PHOSPHOLIPASE D PHOSPHATIDYLINOSITOL-GLYCAN-SPECIFIC PHOSPHOLIPASE D phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;lipase activity#GO:0016298 response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;macromolecule localization#GO:0033036;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular response to insulin stimulus#GO:0032869;transport#GO:0006810;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;protein localization to extracellular region#GO:0071692;response to insulin#GO:0032868;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;response to hormone#GO:0009725;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;export from cell#GO:0140352;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;protein transport#GO:0015031;secretion by cell#GO:0032940;protein secretion#GO:0009306;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLD#P06839 GORGO|Ensembl=ENSGGOG00000003136.3|UniProtKB=G3S9Q8 G3S9Q8 KRT72 PTHR45616:SF2 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 72 structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;developmental process#GO:0032502;epidermis development#GO:0008544;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cellular process#GO:0009987;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009986.3|UniProtKB=G3R3C4 G3R3C4 RIMS3 PTHR12157:SF25 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 3 structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;localization#GO:0051179;regulation of secretion#GO:0051046;cell communication#GO:0007154;secretion#GO:0046903;regulation of exocytosis#GO:0017157;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;regulation of transport#GO:0051049;exocytosis#GO:0006887;regulation of localization#GO:0032879;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of neurotransmitter secretion#GO:0046928;export from cell#GO:0140352;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;presynaptic active zone#GO:0048786;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;presynapse#GO:0098793;cell cortex#GO:0005938;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000012191.3|UniProtKB=G3R917 G3R917 CDHR4 PTHR24028:SF123 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 4 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 GORGO|Ensembl=ENSGGOG00000013308.3|UniProtKB=G3RBX1 G3RBX1 PTHR24147:SF59 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 18B GORGO|Ensembl=ENSGGOG00000002382.3|UniProtKB=G3QIX3 G3QIX3 ALKAL1 PTHR28676:SF1 ALK AND LTK LIGAND 2-RELATED ALK AND LTK LIGAND 1 protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;molecular function regulator activity#GO:0098772;receptor tyrosine kinase binding#GO:0030971;protein kinase activator activity#GO:0030295;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;kinase activator activity#GO:0019209 positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 GORGO|Ensembl=ENSGGOG00000022410.2|UniProtKB=G3RMR8 G3RMR8 CCDC68 PTHR23171:SF3 GDOWN1 COILED-COIL DOMAIN-CONTAINING PROTEIN 68 nuclear protein-containing complex#GO:0140513;sarcomere#GO:0030017;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;I band#GO:0031674;transferase complex#GO:1990234;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;RNA polymerase II, core complex#GO:0005665;intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000007075.3|UniProtKB=G3QVZ3 G3QVZ3 DENND1C PTHR13196:SF25 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1C phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000002210.3|UniProtKB=A0A2I2YAC6 A0A2I2YAC6 CDC73 PTHR12466:SF8 CDC73 DOMAIN PROTEIN PARAFIBROMIN enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000004715.3|UniProtKB=G3QPW3 G3QPW3 CCNG1 PTHR10177:SF59 CYCLINS CYCLIN-G1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>CYCLIN G#G04715;p53 pathway#P00059>Cyclin G#G04689;p53 pathway feedback loops 2#P04398>cyclin G#P04662 GORGO|Ensembl=ENSGGOG00000012071.3|UniProtKB=G3R8R2 G3R8R2 UNC5CL PTHR12582:SF51 NETRIN RECEPTOR UNC5 UNC5C-LIKE PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of JNK cascade#GO:0046328;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040292.1|UniProtKB=A0A2I2YJX5 A0A2I2YJX5 PTHR19944:SF91 MHC CLASS II-RELATED IMMUNOGLOBULIN HEAVY CONSTANT EPSILON peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488;protein-containing complex binding#GO:0044877 regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of cell adhesion#GO:0045785;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037 vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000011047.3|UniProtKB=G3R630 G3R630 AQP8 PTHR45665:SF66 AQUAPORIN-8 AQUAPORIN-8 channel activity#GO:0015267;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 fluid transport#GO:0042044;water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000027464.2|UniProtKB=G3S9C3 G3S9C3 RBIS PTHR35544:SF4 RIBOSOMAL BIOGENESIS FACTOR RIBOSOMAL BIOGENESIS FACTOR GORGO|Ensembl=ENSGGOG00000042467.1|UniProtKB=A0A2I2ZBB7 A0A2I2ZBB7 MECP2 PTHR15074:SF6 METHYL-CPG-BINDING PROTEIN METHYL-CPG-BINDING PROTEIN 2 heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;chromatin binding#GO:0003682 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000037218.1|UniProtKB=A0A2I2Z133 A0A2I2Z133 LOC129525323 PTHR19970:SF26 RIBOSOMAL PROTEIN L39E RIBOSOMAL PROTEIN L39 LIKE 3 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000002467.3|UniProtKB=G3QJ46 G3QJ46 PDK4 PTHR11947:SF22 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 4, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;regulation of lipid metabolic process#GO:0019216;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;regulation of carbohydrate metabolic process#GO:0006109;cellular response to insulin stimulus#GO:0032869;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000016507.3|UniProtKB=G3RK51 G3RK51 PRKAR1A PTHR11635:SF129 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;enzyme inhibitor activity#GO:0004857;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;kinase inhibitor activity#GO:0019210;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;protein kinase A binding#GO:0051018;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Endothelin signaling pathway#P00019>PKA#P00570;GABA-B receptor II signaling#P05731>PKA#P05752;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Hedgehog signaling pathway#P00025>PKA#P00682;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 GORGO|Ensembl=ENSGGOG00000002316.3|UniProtKB=G3QIR6 G3QIR6 ADCY6 PTHR45627:SF11 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 6 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 GABA-B receptor II signaling#P05731>AC#P05760;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841 GORGO|Ensembl=ENSGGOG00000001061.3|UniProtKB=A0A2I2YSB0 A0A2I2YSB0 SLC12A6 PTHR11827:SF66 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 6 symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000007016.3|UniProtKB=G3QVU1 G3QVU1 LOC101138318 PTHR46730:SF3 POLYCYSTIN-1 POLYCYSTIN-1 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000036333.1|UniProtKB=A0A2I2Z962 A0A2I2Z962 LOC101130799 PTHR23310:SF51 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 7 lipid binding#GO:0008289;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000004520.3|UniProtKB=G3SJ82 G3SJ82 GPA33 PTHR44969:SF1 CELL SURFACE A33 ANTIGEN CELL SURFACE A33 ANTIGEN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000015928.3|UniProtKB=G3RIM5 G3RIM5 PRSS57 PTHR24271:SF55 KALLIKREIN-RELATED SERINE PROTEASE 57 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000000208.3|UniProtKB=G3QD94 G3QD94 PTHR22237:SF1 APC MEMBRANE RECRUITMENT PROTEIN 2-RELATED APC MEMBRANE RECRUITMENT PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical Wnt signaling pathway#GO:0060828 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000015953.3|UniProtKB=G3RIP9 G3RIP9 ERAL1 PTHR42698:SF1 GTPASE ERA GTPASE ERA, MITOCHONDRIAL cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex organization#GO:0043933;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;protein-RNA complex assembly#GO:0022618 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000010971.3|UniProtKB=G3R5W0 G3R5W0 PRKCB PTHR24351:SF282 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C BETA TYPE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Metabotropic glutamate receptor group I pathway#P00041>PKC#P01055;Apoptosis signaling pathway#P00006>PKCs#P00318;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;B cell activation#P00010>PKC#P00373;FGF signaling pathway#P00021>PKC#P00648;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Endothelin signaling pathway#P00019>PKC#P00568;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861 GORGO|Ensembl=ENSGGOG00000040045.1|UniProtKB=A0A2I2ZB80 A0A2I2ZB80 TMIGD2 PTHR12231:SF266 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000016858.3|UniProtKB=G3RL18 G3RL18 ABCB8 PTHR24221:SF662 ATP-BINDING CASSETTE SUB-FAMILY B MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000022860.2|UniProtKB=G3RX86 G3RX86 PTHR10772:SF67 10 KDA HEAT SHOCK PROTEIN 10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;protein-folding chaperone binding#GO:0051087;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperonin#PC00073 GORGO|Ensembl=ENSGGOG00000023944.2|UniProtKB=G3RMT1 G3RMT1 RPL26 PTHR11143:SF11 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL24 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000904.3|UniProtKB=G3QF30 G3QF30 BMP6 PTHR11848:SF137 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 6 receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP6/7#P06752;TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000015277.4|UniProtKB=G3RGZ1 G3RGZ1 MEGF9 PTHR10574:SF298 NETRIN/LAMININ-RELATED MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 9 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;substrate adhesion-dependent cell spreading#GO:0034446;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;cell motility#GO:0048870;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;cell-substrate adhesion#GO:0031589;external encapsulating structure organization#GO:0045229;system development#GO:0048731;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;cell migration#GO:0016477;extracellular matrix assembly#GO:0085029;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;basement membrane#GO:0005604;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 GORGO|Ensembl=ENSGGOG00000005835.3|UniProtKB=G3QSR6 G3QSR6 LOC101139685 PTHR19944:SF50 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DM ALPHA CHAIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823;protein-containing complex binding#GO:0044877 regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of cellular process#GO:0048522;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;immune system process#GO:0002376;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of leukocyte activation#GO:0002696 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;protein-containing complex#GO:0032991;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 GORGO|Ensembl=ENSGGOG00000037471.1|UniProtKB=A0A2I2Y5F2 A0A2I2Y5F2 UBE2E3 PTHR24068:SF63 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E3 aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein K48-linked ubiquitination#GO:0070936;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein K63-linked ubiquitination#GO:0070534;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein K11-linked ubiquitination#GO:0070979;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000008059.3|UniProtKB=G3QYE6 G3QYE6 KLRG1 PTHR47648:SF1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY G MEMBER 1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY G MEMBER 1 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000038581.1|UniProtKB=A0A2I2Z6T9 A0A2I2Z6T9 PTHR13848:SF54 PROTEIN YIPPEE-LIKE CG15309-RELATED YIPPEE DOMAIN-CONTAINING PROTEIN ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000027478.2|UniProtKB=G3RWK7 G3RWK7 EPM2AIP1 PTHR45913:SF11 EPM2A-INTERACTING PROTEIN 1 EPM2A-INTERACTING PROTEIN 1 positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of biological process#GO:0050789;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 GORGO|Ensembl=ENSGGOG00000013678.3|UniProtKB=G3RCV9 G3RCV9 ZP1 PTHR23343:SF41 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 1 binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;regulation of reproductive process#GO:2000241;reproductive process#GO:0022414;fertilization#GO:0009566;biological regulation#GO:0065007;single fertilization#GO:0007338;negative regulation of biological process#GO:0048519;cellular process#GO:0009987;regulation of biological process#GO:0050789;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988;sperm-egg recognition#GO:0035036;cell activation#GO:0001775;cell recognition#GO:0008037;sexual reproduction#GO:0019953 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000000209.3|UniProtKB=A0A2I2YEP1 A0A2I2YEP1 CASP8 PTHR48169:SF9 DED DOMAIN-CONTAINING PROTEIN CASPASE-8-LIKE biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of programmed cell death#GO:0043069;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of extrinsic apoptotic signaling pathway#GO:2001236;negative regulation of cell communication#GO:0010648;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057 GORGO|Ensembl=ENSGGOG00000040779.1|UniProtKB=A0A2I2ZBG2 A0A2I2ZBG2 WDR82 PTHR19861:SF0 WD40 REPEAT PROTEIN SWD2 WD REPEAT-CONTAINING PROTEIN 82 binding#GO:0005488;chromatin binding#GO:0003682 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;organelle lumen#GO:0043233;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000005946.3|UniProtKB=G3QT11 G3QT11 PPDPFL PTHR14572:SF1 PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR-LIKE PROTEIN GORGO|Ensembl=ENSGGOG00000011858.3|UniProtKB=A0A2I2ZVA6 A0A2I2ZVA6 PLCD4 PTHR10336:SF31 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-4 phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 GORGO|Ensembl=ENSGGOG00000025822.2|UniProtKB=G3SFF8 G3SFF8 LZTR1 PTHR46376:SF1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of small GTPase mediated signal transduction#GO:0051056;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;regulation of Ras protein signal transduction#GO:0046578;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007331.3|UniProtKB=G3QWL7 G3QWL7 WASF1 PTHR12902:SF8 WASP-1 ACTIN-BINDING PROTEIN WASF1 protein kinase A regulatory subunit binding#GO:0034237;protein kinase A binding#GO:0051018;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 organelle organization#GO:0006996;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;positive regulation of organelle organization#GO:0010638 intracellular anatomical structure#GO:0005622;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;lamellipodium#GO:0030027 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000005115.3|UniProtKB=G3QQX9 G3QQX9 CABS1 PTHR22810:SF1 TESTIS DEVELOPMENT PROTEIN NYD-SP26 CALCIUM-BINDING AND SPERMATID-SPECIFIC PROTEIN 1 calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process#GO:0009987;sperm motility#GO:0097722;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;flagellated sperm motility#GO:0030317 motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;sperm principal piece#GO:0097228;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;cytoplasm#GO:0005737;secretory vesicle#GO:0099503 GORGO|Ensembl=ENSGGOG00000040601.1|UniProtKB=A0A2I2Z622 A0A2I2Z622 ADAM18 PTHR11905:SF158 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 18 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 reproductive structure development#GO:0048608;fertilization#GO:0009566;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;binding of sperm to zona pellucida#GO:0007339;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;system development#GO:0048731;reproductive system development#GO:0061458;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;sexual reproduction#GO:0019953;cell recognition#GO:0008037;multicellular organismal process#GO:0032501;gonad development#GO:0008406;single fertilization#GO:0007338;male gonad development#GO:0008584;cellular process#GO:0009987;sex differentiation#GO:0007548;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell-cell recognition#GO:0009988;metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;sperm-egg recognition#GO:0035036;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;male sex differentiation#GO:0046661 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000008001.3|UniProtKB=A0A2I2Z1D6 A0A2I2Z1D6 NEK1 PTHR44899:SF4 CAMK FAMILY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NEK1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000004400.3|UniProtKB=G3QP38 G3QP38 PTHR12044:SF10 BCL2 INTERACTING MEDIATOR OF CELL DEATH MEIOSIS INHIBITOR PROTEIN 1 reproductive process#GO:0022414;cell cycle process#GO:0022402;cellular process#GO:0009987;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;cell cycle#GO:0007049;organelle organization#GO:0006996;organelle fission#GO:0048285;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;meiotic cell cycle#GO:0051321 GORGO|Ensembl=ENSGGOG00000002303.3|UniProtKB=G3QIP9 G3QIP9 LOC101144282 PTHR26453:SF119 OLFACTORY RECEPTOR ODORANT RECEPTOR M34 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002715.3|UniProtKB=G3QJS3 G3QJS3 ATP1B2 PTHR11523:SF26 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-2 ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;potassium ion homeostasis#GO:0055075;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873 cation-transporting ATPase complex#GO:0090533;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000038671.1|UniProtKB=G3RNP5 G3RNP5 LOC101134211 PTHR23299:SF55 METALLOTHIONEIN METALLOTHIONEIN-1F ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 inorganic ion homeostasis#GO:0098771;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;response to metal ion#GO:0010038;response to cadmium ion#GO:0046686;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;detoxification of inorganic compound#GO:0061687;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;detoxification#GO:0098754;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000002273.3|UniProtKB=A0A2I2YJW7 A0A2I2YJW7 ATP6V1C2 PTHR10137:SF4 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 2 monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829 protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;ATPase complex#GO:1904949 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000014755.3|UniProtKB=G3SEA3 G3SEA3 EMC10 PTHR21397:SF6 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization#GO:0016043 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;EMC complex#GO:0072546;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000016326.3|UniProtKB=G3S0A3 G3S0A3 IL10RA PTHR20859:SF90 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-10 RECEPTOR SUBUNIT ALPHA molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000014186.3|UniProtKB=G3RE64 G3RE64 RPA1 PTHR23273:SF4 REPLICATION FACTOR A 1, RFA1 REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697 telomere organization#GO:0032200;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;reproductive process#GO:0022414;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;RNA-templated DNA biosynthetic process#GO:0006278;DNA repair#GO:0006281;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular component organization#GO:0016043;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;nucleotide-excision repair#GO:0006289;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;replication fork#GO:0005657;replisome#GO:0030894;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000012266.3|UniProtKB=G3R984 G3R984 ZNF487 PTHR23232:SF172 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 487 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000026821.2|UniProtKB=G3S9B5 G3S9B5 GATC PTHR15004:SF0 GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;translation#GO:0006412;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000008207.3|UniProtKB=G3QYS9 G3QYS9 ANKRD49 PTHR24180:SF47 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 49 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 kinase modulator#PC00140;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000002796.3|UniProtKB=G3QJZ4 G3QJZ4 EIF3M PTHR15350:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;eukaryotic translation initiation factor 3 complex#GO:0005852 GORGO|Ensembl=ENSGGOG00000022970.2|UniProtKB=A0A2I2ZD11 A0A2I2ZD11 PSMF1 PTHR13266:SF1 PROTEASOME INHIBITOR PROTEASOME INHIBITOR PI31 SUBUNIT regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000001644.3|UniProtKB=G3QH04 G3QH04 ADORA2B PTHR24246:SF18 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A2B transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;vasodilation#GO:0042311;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of anatomical structure size#GO:0090066;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000008121.3|UniProtKB=G3QYJ8 G3QYJ8 SGCD PTHR12939:SF6 SARCOGLYCAN DELTA-SARCOGLYCAN heart development#GO:0007507;blood circulation#GO:0008015;tissue development#GO:0009888;multicellular organismal process#GO:0032501;heart contraction#GO:0060047;system process#GO:0003008;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;animal organ development#GO:0048513;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;circulatory system development#GO:0072359;heart process#GO:0003015;system development#GO:0048731;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;sarcolemma#GO:0042383 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000014943.3|UniProtKB=A0A2I2Y3I5 A0A2I2Y3I5 SIM2 PTHR23043:SF19 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA SINGLE-MINDED HOMOLOG 2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000042796.1|UniProtKB=A0A2I2YZY0 A0A2I2YZY0 LOC101135182 PTHR23428:SF401 HISTONE H2B HISTONE H2B TYPE F-S antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000026280.2|UniProtKB=G3SD84 G3SD84 PTH2 PTHR28585:SF1 TUBEROINFUNDIBULAR PEPTIDE OF 39 RESIDUES TUBEROINFUNDIBULAR PEPTIDE OF 39 RESIDUES GORGO|Ensembl=ENSGGOG00000002874.3|UniProtKB=A0A2I2Y379 A0A2I2Y379 RUNX1T1 PTHR10379:SF5 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000009680.3|UniProtKB=A0A2I2ZI22 A0A2I2ZI22 DBN1 PTHR10829:SF1 CORTACTIN AND DREBRIN DREBRIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;cellular developmental process#GO:0048869;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin filament polymerization#GO:0030833;regulation of dendritic spine morphogenesis#GO:0061001;system development#GO:0048731;regulation of nervous system development#GO:0051960;regulation of supramolecular fiber organization#GO:1902903;postsynapse organization#GO:0099173;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of dendrite development#GO:0050773;actin cytoskeleton organization#GO:0030036;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of multicellular organismal process#GO:0051239;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;regulation of synapse organization#GO:0050807;positive regulation of neuron projection development#GO:0010976;regulation of cellular component size#GO:0032535;regulation of multicellular organismal development#GO:2000026;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;positive regulation of developmental process#GO:0051094;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;actin filament-based process#GO:0030029;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;regulation of dendrite morphogenesis#GO:0048814;regulation of neurogenesis#GO:0050767;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;positive regulation of cell differentiation#GO:0045597;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;regulation of actin filament length#GO:0030832;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of multicellular organismal process#GO:0051240;regulation of organelle organization#GO:0033043;regulation of postsynapse organization#GO:0099175;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902 actin filament#GO:0005884;synaptic membrane#GO:0097060;cell junction#GO:0030054;neuron projection#GO:0043005;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;postsynaptic membrane#GO:0045211;supramolecular fiber#GO:0099512;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;postsynapse#GO:0098794;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane region#GO:0098590;dendritic tree#GO:0097447;dendrite#GO:0030425;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000016813.3|UniProtKB=G3S4R3 G3S4R3 SLC2A14 PTHR23503:SF53 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 14 sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000015925.3|UniProtKB=G3RIN1 G3RIN1 BMX PTHR24418:SF91 TYROSINE-PROTEIN KINASE CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 GORGO|Ensembl=ENSGGOG00000028265.2|UniProtKB=G3RZP1 G3RZP1 TRAPPC8 PTHR12975:SF6 TRANSPORT PROTEIN TRAPP TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000016844.3|UniProtKB=G3RL06 G3RL06 ATG9B PTHR13038:SF14 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9B lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;reticulophagy#GO:0061709;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;cellular component organization#GO:0016043;localization#GO:0051179;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925 autophagosome#GO:0005776;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000004024.3|UniProtKB=A0A2I2YJ86 A0A2I2YJ86 CPT2 PTHR22589:SF51 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000007667.2|UniProtKB=G3QXF7 G3QXF7 ZG16B PTHR33589:SF1 OS11G0524900 PROTEIN PANCREATIC ADENOCARCINOMA UP-REGULATED FACTOR cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000008956.3|UniProtKB=G3R0Q9 G3R0Q9 KCNJ8 PTHR11767:SF11 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 8 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000009620.3|UniProtKB=A0A2I2Y9Z7 A0A2I2Y9Z7 LYST PTHR13743:SF86 BEIGE/BEACH-RELATED LYSOSOMAL-TRAFFICKING REGULATOR cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;lysosome organization#GO:0007040;lytic vacuole organization#GO:0080171 lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003769.3|UniProtKB=G3RYB6 G3RYB6 NFKBIZ PTHR24124:SF5 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR ZETA biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000041238.1|UniProtKB=A0A2I2YFD2 A0A2I2YFD2 PTHR12138:SF133 PRIMATE-EXPANDED PROTEIN FAMILY SECRETED PROTEIN GORGO|Ensembl=ENSGGOG00000012723.3|UniProtKB=A0A2I2ZEY9 A0A2I2ZEY9 LOC101144446 PTHR48001:SF223 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002685.3|UniProtKB=G3QJP7 G3QJP7 TAF1B PTHR31576:SF6 TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;rRNA transcription#GO:0009303;transcription by RNA polymerase I#GO:0006360;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 General transcription by RNA polymerase I#P00022>TAF-IB#P00650 GORGO|Ensembl=ENSGGOG00000021990.2|UniProtKB=A0A2I2Z1T3 A0A2I2Z1T3 ZNF830 PTHR13278:SF0 ZINC FINGER PROTEIN 830 ZINC FINGER PROTEIN 830 signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic DNA replication checkpoint signaling#GO:0033314;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;signal transduction#GO:0007165;cellular process#GO:0009987;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;biological regulation#GO:0065007;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic cell cycle process#GO:1903047;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040176.1|UniProtKB=A0A2I2ZUU4 A0A2I2ZUU4 VEGFC PTHR12025:SF3 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR C molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488 positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;tube development#GO:0035295;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of locomotion#GO:0040017;response to hypoxia#GO:0001666;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte migration#GO:0002685;response to growth factor#GO:0070848;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;anatomical structure development#GO:0048856;positive regulation of chemotaxis#GO:0050921;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;cell surface receptor signaling pathway#GO:0007166;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;positive regulation of response to external stimulus#GO:0032103;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;response to abiotic stimulus#GO:0009628;response to endogenous stimulus#GO:0009719;positive regulation of cell motility#GO:2000147;vascular endothelial growth factor receptor signaling pathway#GO:0048010;regulation of chemotaxis#GO:0050920;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;cellular response to growth factor stimulus#GO:0071363;angiogenesis#GO:0001525 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000024301.2|UniProtKB=G3RQU6 G3RQU6 LOC101129979 PTHR26453:SF69 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000024562.2|UniProtKB=G3SBM2 G3SBM2 PTHR23413:SF23 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N RIBOSOMAL PROTEIN L32 LIKE 1 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000557.3|UniProtKB=A0A2I2ZIP6 A0A2I2ZIP6 NDUFA8 PTHR13344:SF0 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8 membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000039875.1|UniProtKB=A0A2I2YIE3 A0A2I2YIE3 PTHR23410:SF23 RIBOSOMAL PROTEIN L5-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL18 C-TERMINAL EUKARYOTES DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;ribosomal large subunit assembly#GO:0000027;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;positive regulation of biosynthetic process#GO:0009891;protein-RNA complex assembly#GO:0022618;positive regulation of translation#GO:0045727 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007865.3|UniProtKB=G3QXX0 G3QXX0 PGM2L1 PTHR45745:SF2 PHOSPHOMANNOMUTASE 45A GLUCOSE 1,6-BISPHOSPHATE SYNTHASE isomerase activity#GO:0016853;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;intramolecular phosphotransferase activity#GO:0016868;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773;intramolecular transferase activity#GO:0016866 cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine nucleoside metabolic process#GO:0042278;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine-containing compound biosynthetic process#GO:0072522;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137 metabolite interconversion enzyme#PC00262;isomerase#PC00135;mutase#PC00160 GORGO|Ensembl=ENSGGOG00000001074.3|UniProtKB=G3QFI5 G3QFI5 GLB1L3 PTHR23421:SF59 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE-1-LIKE PROTEIN 3 catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987 hydrolase#PC00121;galactosidase#PC00104 GORGO|Ensembl=ENSGGOG00000009678.4|UniProtKB=G3R2K1 G3R2K1 ESR1 PTHR48092:SF16 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN RECEPTOR binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837 response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to steroid hormone stimulus#GO:0071383;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;estrogen receptor signaling pathway#GO:0030520;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;steroid hormone receptor signaling pathway#GO:0043401;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;response to steroid hormone#GO:0048545 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000042544.1|UniProtKB=A0A2I2YCH5 A0A2I2YCH5 LOC101132832 PTHR11594:SF8 40S RIBOSOMAL PROTEIN S27 40S RIBOSOMAL PROTEIN S27 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome biogenesis#GO:0042254;translation#GO:0006412;nucleic acid biosynthetic process#GO:0141187;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013011.3|UniProtKB=G3RB63 G3RB63 ATP1A4 PTHR43294:SF3 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-4 ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;export from cell#GO:0140352;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;potassium ion homeostasis#GO:0055075;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell projection#GO:0042995;plasma membrane#GO:0005886;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000012202.3|UniProtKB=G3R928 G3R928 RHBDD3 PTHR43066:SF16 RHOMBOID-RELATED PROTEIN RHOMBOID DOMAIN-CONTAINING PROTEIN 3 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 GORGO|Ensembl=ENSGGOG00000009784.3|UniProtKB=G3S8F9 G3S8F9 ZNF132 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008505.3|UniProtKB=G3SJX1 G3SJX1 PTHR11937:SF409 ACTIN ACTIN-RELATED PROTEIN 2 structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;cytoskeletal protein binding#GO:0008092;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314 cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Cadherin signaling pathway#P00012>F-actin#P00470;Alzheimer disease-presenilin pathway#P00004>actin#P00114 GORGO|Ensembl=ENSGGOG00000006697.4|UniProtKB=G3QUZ1 G3QUZ1 JPH2 PTHR23085:SF26 GH28348P JUNCTOPHILIN-2 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sarcoplasmic reticulum#GO:0016529;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000026803.2|UniProtKB=G3RRX8 G3RRX8 ADGRL4 PTHR12011:SF59 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR L4 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040477.1|UniProtKB=G3RQV3 G3RQV3 PTHR15302:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF103 E3 UBIQUITIN-PROTEIN LIGASE RNF103 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787 protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;response to stress#GO:0006950;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;response to chemical#GO:0042221;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000041774.1|UniProtKB=A0A2I2ZRB7 A0A2I2ZRB7 ZNF433 PTHR24377:SF837 IP01015P-RELATED ZINC FINGER PROTEIN 20 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000028620.3|UniProtKB=G3S214 G3S214 TMEM117 PTHR31226:SF1 TRANSMEMBRANE PROTEIN 117 TRANSMEMBRANE PROTEIN 117 apoptotic signaling pathway#GO:0097190;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000022646.2|UniProtKB=G3SH37 G3SH37 SLC2A8 PTHR48021:SF18 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 8 sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000002711.3|UniProtKB=A0A2I2ZP14 A0A2I2ZP14 RAI1 PTHR14955:SF6 RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20 RETINOIC ACID-INDUCED PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 rhythmic process#GO:0048511;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000008038.3|UniProtKB=G3QYC8 G3QYC8 LRRC75B PTHR39654:SF5 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75A-LIKE ISOFORM X1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75B GORGO|Ensembl=ENSGGOG00000003638.3|UniProtKB=G3QM50 G3QM50 ATP6V0B PTHR10263:SF18 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 21 KDA PROTEOLIPID SUBUNIT C'' membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP synthase#PC00002;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000011345.3|UniProtKB=G3R6U4 G3R6U4 PRDM15 PTHR24409:SF353 ZINC FINGER PROTEIN 142 PR DOMAIN ZINC FINGER PROTEIN 15 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010622.4|UniProtKB=G3R4Z6 G3R4Z6 CEP72 PTHR23311:SF7 HEAT SHOCK REGULATED 2 CENTROSOMAL PROTEIN OF 72 KDA microtubule cytoskeleton organization#GO:0000226;regulation of protein localization#GO:0032880;organelle assembly#GO:0070925;centriole replication#GO:0007099;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule organizing center organization#GO:0031023;regulation of localization#GO:0032879;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriolar satellite#GO:0034451 GORGO|Ensembl=ENSGGOG00000002787.4|UniProtKB=G3QJZ3 G3QJZ3 EML6 PTHR13720:SF52 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 6 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000007378.3|UniProtKB=G3QWQ4 G3QWQ4 GPR31 PTHR46048:SF7 HYDROXYCARBOXYLIC ACID RECEPTOR 2 12-(S)-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID RECEPTOR bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000012750.3|UniProtKB=G3RAI2 G3RAI2 SNED1 PTHR24044:SF411 NOTCH LIGAND FAMILY MEMBER SUSHI, NIDOGEN AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000012082.3|UniProtKB=G3R8R5 G3R8R5 TSPO2 PTHR10057:SF4 PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR TRANSLOCATOR PROTEIN 2 mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000005262.3|UniProtKB=G3QRB2 G3QRB2 PTHR22804:SF42 AGGRECAN/VERSICAN PROTEOGLYCAN AGGRECAN CORE PROTEIN nervous system development#GO:0007399;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856 extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;extracellular region#GO:0005576;cell junction#GO:0030054 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 GORGO|Ensembl=ENSGGOG00000014176.3|UniProtKB=G3RY55 G3RY55 CRNKL1 PTHR11246:SF3 PRE-MRNA SPLICING FACTOR CROOKED NECK-LIKE PROTEIN 1 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000015365.3|UniProtKB=A0A2I2ZDP8 A0A2I2ZDP8 RPL36 PTHR10114:SF28 60S RIBOSOMAL PROTEIN L36 RPL36 ALTERNATIVE READING FRAME PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000008731.4|UniProtKB=G3R071 G3R071 SBF2 PTHR10807:SF4 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 13 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;phosphoric ester hydrolase activity#GO:0042578;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644 membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000026119.2|UniProtKB=G3SE08 G3SE08 ZFP91 PTHR46179:SF11 ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZFP91 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016470.3|UniProtKB=G3RK12 G3RK12 PTHR10361:SF40 SODIUM-BILE ACID COTRANSPORTER HEPATIC SODIUM_BILE ACID COTRANSPORTER solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;bile acid transmembrane transporter activity#GO:0015125;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;lipid transport#GO:0006869;macromolecule localization#GO:0033036 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000014029.3|UniProtKB=G3RDS5 G3RDS5 LOC101137192 PTHR24291:SF43 CYTOCHROME P450 FAMILY 4 AROMATASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 developmental process involved in reproduction#GO:0003006;reproductive structure development#GO:0048608;reproductive process#GO:0022414;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;female gonad development#GO:0008585;reproductive system development#GO:0061458;anatomical structure development#GO:0048856;sex differentiation#GO:0007548;response to estradiol#GO:0032355;gonad development#GO:0008406;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;response to lipid#GO:0033993;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;multicellular organism development#GO:0007275;animal organ development#GO:0048513 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 Androgen/estrogene/progesterone biosynthesis#P02727>Aromatase#P02828 GORGO|Ensembl=ENSGGOG00000023022.2|UniProtKB=G3RT27 G3RT27 EXOC5 PTHR12100:SF4 SEC10 EXOCYST COMPLEX COMPONENT 5 transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;exocyst#GO:0000145;cytoplasm#GO:0005737;cell cortex#GO:0005938;cell periphery#GO:0071944;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000011295.3|UniProtKB=A0A2I2ZX86 A0A2I2ZX86 INPPL1 PTHR46051:SF2 SH2 DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 PI3 kinase pathway#P00048>SHIP#P01200;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SHIP#P00839;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>SHIP2#P00897 GORGO|Ensembl=ENSGGOG00000001129.3|UniProtKB=G3RPQ2 G3RPQ2 ACBD3 PTHR22973:SF11 LD35087P GOLGI RESIDENT PROTEIN GCP60 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000001381.3|UniProtKB=G3QGB4 G3QGB4 XPA PTHR10142:SF0 DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;damaged DNA binding#GO:0003684 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;response to UV#GO:0009411;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular response to abiotic stimulus#GO:0071214;chromosome organization#GO:0051276;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;nucleotide-excision repair#GO:0006289;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;base-excision repair#GO:0006284;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to environmental stimulus#GO:0104004;cellular response to radiation#GO:0071478 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 GORGO|Ensembl=ENSGGOG00000039851.1|UniProtKB=A0A2I2ZER6 A0A2I2ZER6 LOC101130471 PTHR24012:SF409 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1 mRNA binding#GO:0003729;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;single-stranded RNA binding#GO:0003727 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004881.3|UniProtKB=G3QQB7 G3QQB7 TMEM267 PTHR13628:SF1 TRANSMEMBRANE PROTEIN 267 TRANSMEMBRANE PROTEIN 267 GORGO|Ensembl=ENSGGOG00000004761.3|UniProtKB=G3QQ08 G3QQ08 SF3B4 PTHR48030:SF4 SPLICING FACTOR 3B SUBUNIT 4 SPLICING FACTOR 3B SUBUNIT 4 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000014863.3|UniProtKB=G3S629 G3S629 MYRFL PTHR13029:SF17 FAMILY NOT NAMED MYELIN REGULATORY FACTOR-LIKE PROTEIN DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000015145.3|UniProtKB=G3RGN0 G3RGN0 MAPDA PTHR11409:SF42 ADENOSINE DEAMINASE N6-METHYL-AMP DEAMINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000 nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;small molecule biosynthetic process#GO:0044283;purine nucleobase metabolic process#GO:0006144;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;nucleoside catabolic process#GO:0009164;purine nucleoside metabolic process#GO:0042278;purine-containing compound biosynthetic process#GO:0072522;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 deaminase#PC00088 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 GORGO|Ensembl=ENSGGOG00000007939.3|UniProtKB=A0A2I2YG23 A0A2I2YG23 LOC101135098 PTHR45720:SF16 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN CLC-KA voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000003162.3|UniProtKB=G3QKX7 G3QKX7 C8H10orf90 PTHR21553:SF24 ALMS1-RELATED (E2-INDEPENDENT) E3 UBIQUITIN-CONJUGATING ENZYME FATS transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 regulation of microtubule-based process#GO:0032886;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000015299.3|UniProtKB=A0A2I2Z608 A0A2I2Z608 PTHR11461:SF161 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B13 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000003149.3|UniProtKB=G3QKW3 G3QKW3 PMP22 PTHR10671:SF117 EPITHELIAL MEMBRANE PROTEIN-RELATED PERIPHERAL MYELIN PROTEIN 22 immune effector process#GO:0002252;positive regulation of inflammatory response#GO:0050729;positive regulation of response to external stimulus#GO:0032103;natural killer cell mediated cytotoxicity#GO:0042267;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;immune system process#GO:0002376;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;regulation of biological process#GO:0050789;natural killer cell mediated immunity#GO:0002228;leukocyte mediated cytotoxicity#GO:0001909;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;cell killing#GO:0001906;regulation of response to stress#GO:0080134;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;response to external biotic stimulus#GO:0043207 membrane#GO:0016020;lysosome#GO:0005764;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000017116.3|UniProtKB=G3RLP6 G3RLP6 CA14 PTHR18952:SF84 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 14 catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000037185.1|UniProtKB=A0A2I2ZL64 A0A2I2ZL64 PTHR45793:SF24 HOMEOBOX PROTEIN HOMEOBOX DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000022681.1|UniProtKB=G3RRH4 G3RRH4 ND1 PTHR11432:SF23 NADH DEHYDROGENASE SUBUNIT 1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 1 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824 cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000010354.3|UniProtKB=G3R4A4 G3R4A4 TAS2R16 PTHR11394:SF68 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 16 transmembrane signaling receptor activity#GO:0004888;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000044213.1|UniProtKB=A0A2I2YDI9 A0A2I2YDI9 ZCCHC3 PTHR22639:SF4 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of cytokine production#GO:0001817;activation of innate immune response#GO:0002218;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;cellular response to nitrogen compound#GO:1901699;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of gene expression#GO:0010628;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of type I interferon production#GO:0032481;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;positive regulation of cytokine production#GO:0001819;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;response to nitrogen compound#GO:1901698;positive regulation of biosynthetic process#GO:0009891;response to virus#GO:0009615;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;regulation of multicellular organismal process#GO:0051239;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;defense response to virus#GO:0051607;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of signaling#GO:0023056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 GORGO|Ensembl=ENSGGOG00000037481.1|UniProtKB=A0A2I2YUS2 A0A2I2YUS2 LOC101132030 PTHR10638:SF94 COPPER AMINE OXIDASE AMINE OXIDASE metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;oxidoreductase activity#GO:0016491;copper ion binding#GO:0005507;catalytic activity#GO:0003824 metabolic process#GO:0008152;amine metabolic process#GO:0009308;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000003522.3|UniProtKB=G3QLU6 G3QLU6 BCL2L10 PTHR11256:SF47 BCL-2 RELATED BCL-2-LIKE PROTEIN 10 channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;positive regulation of cellular process#GO:0048522;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 Apoptosis signaling pathway#P00006>Diva#P00285 GORGO|Ensembl=ENSGGOG00000007838.3|UniProtKB=G3QXW2 G3QXW2 AGTPBP1 PTHR12756:SF24 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 1 peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cytoskeletal protein binding#GO:0008092;metalloexopeptidase activity#GO:0008235;tubulin binding#GO:0015631;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;protein binding#GO:0005515;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;binding#GO:0005488 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000014362.3|UniProtKB=G3REM5 G3REM5 RNF214 PTHR15727:SF3 RING FINGER PROTEIN 214 RING FINGER PROTEIN 214 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 GORGO|Ensembl=ENSGGOG00000024462.2|UniProtKB=G3SI26 G3SI26 PTHR12138:SF163 PRIMATE-EXPANDED PROTEIN FAMILY DOWN SYNDROME CRITICAL REGION PROTEIN 8 GORGO|Ensembl=ENSGGOG00000013912.3|UniProtKB=G3RDH6 G3RDH6 PPFIA4 PTHR12587:SF5 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-4 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 presynapse#GO:0098793;synapse#GO:0045202;presynaptic active zone#GO:0048786;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000016883.3|UniProtKB=A0A2I2Z156 A0A2I2Z156 ACSL6 PTHR43272:SF54 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 6 ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;monocarboxylic acid metabolic process#GO:0032787;long-chain fatty acid metabolic process#GO:0001676;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000016348.3|UniProtKB=G3RJQ8 G3RJQ8 CHERP PTHR12323:SF0 SR-RELATED CTD ASSOCIATED FACTOR 6 CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;calcium ion homeostasis#GO:0055074 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;perinuclear region of cytoplasm#GO:0048471 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000040806.1|UniProtKB=A0A2I2Y6J6 A0A2I2Y6J6 SF3B6 PTHR48526:SF2 SPLICING FACTOR 3B SUBUNIT 6 SPLICING FACTOR 3B SUBUNIT 6 GORGO|Ensembl=ENSGGOG00000006602.3|UniProtKB=A0A2I2YZZ8 A0A2I2YZZ8 LOC109029034 PTHR45616:SF52 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CUTICULAR HB3 structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;epidermis development#GO:0008544;developmental process#GO:0032502;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;skin development#GO:0043588;organelle organization#GO:0006996;cellular process#GO:0009987;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 GORGO|Gene=MT-ND6|UniProtKB=Q34573 Q34573 MT-ND6 PTHR11435:SF1 NADH UBIQUINONE OXIDOREDUCTASE SUBUNIT ND6 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000017000.3|UniProtKB=G3RLF0 G3RLF0 RNF111 PTHR16200:SF4 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ARKADIA catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515 regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000014482.3|UniProtKB=G3REX6 G3REX6 SLX9 PTHR31109:SF3 PROTEIN FAM207A RIBOSOME BIOGENESIS PROTEIN SLX9 HOMOLOG GORGO|Ensembl=ENSGGOG00000014827.3|UniProtKB=A0A2I2Y5Q5 A0A2I2Y5Q5 RPL37A PTHR48129:SF1 60S RIBOSOMAL PROTEIN L37A LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007853.3|UniProtKB=G3QXW5 G3QXW5 P4HA3 PTHR10869:SF223 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-3 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000026672.2|UniProtKB=G3RWH4 G3RWH4 S100A3 PTHR11639:SF12 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A3 metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000005358.3|UniProtKB=G3S374 G3S374 PPP6R1 PTHR12634:SF13 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 1 protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000025768.2|UniProtKB=A0A2I2ZJD2 A0A2I2ZJD2 DOCK7 PTHR23317:SF78 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 7 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;regulation of small GTPase mediated signal transduction#GO:0051056;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;regulation of Rho protein signal transduction#GO:0035023;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;anatomical structure development#GO:0048856;system development#GO:0048731 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000015586.3|UniProtKB=G3RHS8 G3RHS8 SAMD14 PTHR16154:SF28 NEURABIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 14 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein-membrane adaptor activity#GO:0043495;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin binding#GO:0003779;actin filament binding#GO:0051015;molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092 calcium-mediated signaling#GO:0019722;neurogenesis#GO:0022008;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;neuron projection development#GO:0031175;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 filopodium#GO:0030175;dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;postsynapse#GO:0098794;cell cortex#GO:0005938;actin-based cell projection#GO:0098858;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;neuron projection#GO:0043005;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000012657.3|UniProtKB=G3RA87 G3RA87 RNF215 PTHR22765:SF345 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING FINGER PROTEIN 215 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000007543.3|UniProtKB=A0A2I2ZA16 A0A2I2ZA16 USP33 PTHR21646:SF32 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 33 cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 developmental process#GO:0032502;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;multicellular organism development#GO:0007275;regulation of protein stability#GO:0031647;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000000198.3|UniProtKB=G3QD85 G3QD85 CLEC9A PTHR47727:SF1 C-TYPE LECTIN DOMAIN FAMILY 9 MEMBER A C-TYPE LECTIN DOMAIN FAMILY 9 MEMBER A transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 GORGO|Ensembl=ENSGGOG00000010357.3|UniProtKB=G3R4B2 G3R4B2 ENO1 PTHR11902:SF12 ENOLASE ALPHA-ENOLASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824;phosphopyruvate hydratase activity#GO:0004634 nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;catalytic complex#GO:1902494 lyase#PC00144;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Enolase#P00678 GORGO|Ensembl=ENSGGOG00000038599.1|UniProtKB=A0A2I2ZJ79 A0A2I2ZJ79 PTHR32267:SF2 T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN GORGO|Ensembl=ENSGGOG00000005619.3|UniProtKB=G3QS78 G3QS78 FKTN PTHR15407:SF42 FUKUTIN-RELATED RIBITOL-5-PHOSPHATE TRANSFERASE FKTN glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000024690.2|UniProtKB=A0A2I2Y3K2 A0A2I2Y3K2 FOXL2 PTHR11829:SF411 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000008576.3|UniProtKB=G3QZS0 G3QZS0 ACP2 PTHR11567:SF180 ACID PHOSPHATASE-RELATED LYSOSOMAL ACID PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;acid phosphatase activity#GO:0003993;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 lysosome organization#GO:0007040;cellular process#GO:0009987;lytic vacuole organization#GO:0080171;cellular component organization#GO:0016043;organelle organization#GO:0006996;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000024548.2|UniProtKB=G3SBI8 G3SBI8 PTHR10934:SF6 60S RIBOSOMAL PROTEIN L18 LARGE RIBOSOMAL SUBUNIT PROTEIN EL18 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000799.3|UniProtKB=A0A2I2ZIT6 A0A2I2ZIT6 CALCB PTHR10505:SF3 CALCITONIN-RELATED CALCITONIN GENE-RELATED PEPTIDE 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 GORGO|Gene=A4GALT|UniProtKB=Q9N290 Q9N290 A4GALT PTHR12042:SF17 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247 transferase#PC00220;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000017083.3|UniProtKB=G3SJG5 G3SJG5 WNT9B PTHR12027:SF84 WNT RELATED PROTEIN WNT-9B molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;system development#GO:0048731;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 GORGO|Ensembl=ENSGGOG00000012395.3|UniProtKB=G3R9K7 G3R9K7 DNAJC25 PTHR44176:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000016785.3|UniProtKB=G3RKU6 G3RKU6 FBXO40 PTHR15933:SF1 PROTEIN CBG16327 F-BOX ONLY PROTEIN 40 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014435.3|UniProtKB=G3REV3 G3REV3 PDLIM7 PTHR24214:SF0 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 7 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;circulatory system development#GO:0072359;cellular component organization#GO:0016043;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;multicellular organismal process#GO:0032501;heart development#GO:0007507;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular organelle#GO:0043229;myofibril#GO:0030016;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;stress fiber#GO:0001725;I band#GO:0031674;actin filament#GO:0005884;cell junction#GO:0030054;sarcomere#GO:0030017;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;adherens junction#GO:0005912;cell-cell junction#GO:0005911;contractile muscle fiber#GO:0043292;actomyosin#GO:0042641;Z disc#GO:0030018;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000038600.1|UniProtKB=A0A2I2YKP0 A0A2I2YKP0 LOC101141543 PTHR11691:SF64 TYPE I INTERFERON INTERFERON ALPHA-1-RELATED signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677 immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;adaptive immune response#GO:0002250;multicellular organismal process#GO:0032501;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;lymphocyte activation involved in immune response#GO:0002285;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;T cell activation involved in immune response#GO:0002286;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;leukocyte activation involved in immune response#GO:0002366;natural killer cell activation#GO:0030101;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;humoral immune response#GO:0006959;B cell activation#GO:0042113;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;T cell activation#GO:0042110;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune system process#GO:0002376;B cell activation involved in immune response#GO:0002312;type I interferon-mediated signaling pathway#GO:0060337;response to peptide#GO:1901652;cell activation involved in immune response#GO:0002263 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127;cytokine#PC00083 GORGO|Ensembl=ENSGGOG00000008572.3|UniProtKB=A0A2I2Z7B1 A0A2I2Z7B1 POC1B PTHR44019:SF1 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG B organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000014299.3|UniProtKB=G3REG6 G3REG6 ABHD12 PTHR12277:SF61 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN LYSOPHOSPHATIDYLSERINE LIPASE ABHD12 hydrolase activity#GO:0016787;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;lipase activity#GO:0016298;phospholipase activity#GO:0120569;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 glycerophospholipid metabolic process#GO:0006650;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;acylglycerol catabolic process#GO:0046464;glycerophospholipid catabolic process#GO:0046475;neutral lipid metabolic process#GO:0006638;neutral lipid catabolic process#GO:0046461;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;glycerolipid catabolic process#GO:0046503 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000000736.3|UniProtKB=G3QEM8 G3QEM8 PLXND1 PTHR22625:SF7 PLEXIN PLEXIN-D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of multicellular organismal development#GO:2000026;regulation of cell shape#GO:0008360;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;signaling#GO:0023052;synapse assembly#GO:0007416;positive regulation of nervous system development#GO:0051962;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;cellular component assembly#GO:0022607;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;system development#GO:0048731;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;negative regulation of cell adhesion#GO:0007162;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005386.3|UniProtKB=G3S5U0 G3S5U0 TAS1R3 PTHR24061:SF435 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 3 transmembrane signaling receptor activity#GO:0004888;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002827.3|UniProtKB=A0A2I2Z3U7 A0A2I2Z3U7 COPS2 PTHR10678:SF3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 COP9 SIGNALOSOME COMPLEX SUBUNIT 2 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180 GORGO|Ensembl=ENSGGOG00000001324.3|UniProtKB=G3QG56 G3QG56 HELT PTHR10985:SF8 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY AND ENHANCER OF SPLIT-RELATED PROTEIN HELT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;pattern specification process#GO:0007389;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 GORGO|Ensembl=ENSGGOG00000042597.1|UniProtKB=A0A2I2YHN1 A0A2I2YHN1 ZNF664 PTHR24404:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 835 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016400.3|UniProtKB=G3RNJ9 G3RNJ9 HTR4 PTHR24248:SF66 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 4 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016192.3|UniProtKB=G3SBY0 G3SBY0 CLK1 PTHR45646:SF4 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000042603.1|UniProtKB=A0A2I2ZSX9 A0A2I2ZSX9 ZSCAN22 PTHR23226:SF59 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 22 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000005400.3|UniProtKB=G3QRM9 G3QRM9 MAP6 PTHR14759:SF29 STOP PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 6 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 positive regulation of cell projection organization#GO:0031346;regulation of microtubule-based process#GO:0032886;anatomical structure development#GO:0048856;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;regulation of cell projection organization#GO:0031344;intracellular transport#GO:0046907;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular localization#GO:0051641;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;positive regulation of multicellular organismal process#GO:0051240;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of neuron projection development#GO:0010975;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;cell morphogenesis involved in neuron differentiation#GO:0048667;system development#GO:0048731;localization#GO:0051179;regulation of nervous system development#GO:0051960;dendrite morphogenesis#GO:0048813;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;regulation of cytoskeleton organization#GO:0051493;developmental process#GO:0032502;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;positive regulation of axonogenesis#GO:0050772;dendrite development#GO:0016358;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;cell projection organization#GO:0030030;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;regulation of axonogenesis#GO:0050770;regulation of multicellular organismal process#GO:0051239;regulation of microtubule cytoskeleton organization#GO:0070507 dendritic tree#GO:0097447;intracellular organelle#GO:0043229;axon#GO:0030424;dendrite#GO:0030425;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;cis-Golgi network#GO:0005801;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080 GORGO|Ensembl=ENSGGOG00000000377.3|UniProtKB=G3QDP6 G3QDP6 ANKS6 PTHR10627:SF70 SCP160 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 6 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000013757.3|UniProtKB=G3RD25 G3RD25 SMIM20 PTHR34923:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 20 SMALL INTEGRAL MEMBRANE PROTEIN 20 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 GORGO|Ensembl=ENSGGOG00000002659.3|UniProtKB=Q2IBF5 Q2IBF5 ASZ1 PTHR24157:SF3 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 male gamete generation#GO:0048232;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;spermatogenesis#GO:0007283;gamete generation#GO:0007276;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;negative regulation of metabolic process#GO:0009892;developmental process involved in reproduction#GO:0003006;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P granule#GO:0043186 GORGO|Ensembl=ENSGGOG00000002648.3|UniProtKB=G3RX58 G3RX58 PLA2G3 PTHR12253:SF19 RH14732P GROUP 3 SECRETORY PHOSPHOLIPASE A2 GORGO|Ensembl=ENSGGOG00000010114.3|UniProtKB=G3R3N9 G3R3N9 KAT14 PTHR20916:SF26 CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;protein N-acyltransferase activity#GO:0140186 GORGO|Ensembl=ENSGGOG00000008825.3|UniProtKB=A0A2I2Z175 A0A2I2Z175 GRM5 PTHR24060:SF30 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066 cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell surface receptor signaling pathway#GO:0007166;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 G-protein coupled receptor#PC00021 Metabotropic glutamate receptor group I pathway#P00041>mGluR5#P01061;Metabotropic glutamate receptor group III pathway#P00039>mGluR 5#P01037;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Metabotropic glutamate receptor group I pathway#P00041>mGluR1#P01062;Endogenous cannabinoid signaling#P05730>mGluR#P05748;Metabotropic glutamate receptor group III pathway#P00039>mGluR 1/5#P01040;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 GORGO|Ensembl=ENSGGOG00000009217.3|UniProtKB=A0A2I2YZ08 A0A2I2YZ08 THEMIS2 PTHR15215:SF2 CABIT DOMAIN-CONTAINING PROTEIN PROTEIN THEMIS2 cell communication#GO:0007154;regulation of immune response#GO:0050776;immune system process#GO:0002376;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013658.3|UniProtKB=A0A2I2YDV5 A0A2I2YDV5 SEC62 PTHR12443:SF9 TRANSLOCATION PROTEIN SEC62 TRANSLOCATION PROTEIN SEC62 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transmembrane protein transporter activity#GO:0008320 establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;post-translational protein targeting to membrane, translocation#GO:0031204;protein transport#GO:0015031 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000042183.1|UniProtKB=A0A2I2ZVR6 A0A2I2ZVR6 PTHR23268:SF45 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 2 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000002337.3|UniProtKB=G3QIT3 G3QIT3 PTHR18839:SF4 MITOTIC INTERACTOR AND SUBSTRATE OF PLK1 MISP FAMILY MEMBER MISP FAMILY MEMBER 3 GORGO|Ensembl=ENSGGOG00000013974.3|UniProtKB=A0A2I2Y4M4 A0A2I2Y4M4 CPNE8 PTHR10857:SF133 COPINE COPINE-8 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 response to chemical#GO:0042221;response to calcium ion#GO:0051592;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to metal ion#GO:0010038;cellular response to chemical stimulus#GO:0070887 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000027704.2|UniProtKB=A0A2I2YPU7 A0A2I2YPU7 PTHR12850:SF18 40S RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN ES25 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006460.3|UniProtKB=A0A2I2YT14 A0A2I2YT14 SENP6 PTHR46896:SF1 SENTRIN-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 6 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;macromolecule metabolic process#GO:0043170;regulation of organelle assembly#GO:1902115;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of microtubule cytoskeleton organization#GO:0070507;protein modification by small protein conjugation or removal#GO:0070647;regulation of microtubule-based process#GO:0032886;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of spindle assembly#GO:0090169;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of protein-containing complex assembly#GO:0043254;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of cytoskeleton organization#GO:0051493;regulation of spindle organization#GO:0090224;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000012399.3|UniProtKB=G3R9L2 G3R9L2 RAB3IL1 PTHR14430:SF5 RABIN3-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR FOR RAB-3A GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 GORGO|Ensembl=ENSGGOG00000014952.3|UniProtKB=G3RV31 G3RV31 GRAMD1A PTHR23319:SF8 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-A sterol binding#GO:0032934;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;cholesterol binding#GO:0015485;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;steroid binding#GO:0005496;alcohol binding#GO:0043178;cholesterol transfer activity#GO:0120020 lipid localization#GO:0010876;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;sterol transport#GO:0015918;organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lipid transport#GO:0006869;intracellular sterol transport#GO:0032366 organelle membrane contact site#GO:0044232;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000040126.1|UniProtKB=A0A2I2Y4C6 A0A2I2Y4C6 PTHR23232:SF177 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000026699.2|UniProtKB=G3S3A2 G3S3A2 ZNF628 PTHR24390:SF279 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 711 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000041053.1|UniProtKB=A0A2I2YB48 A0A2I2YB48 SNRPD1 PTHR23338:SF18 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U4 snRNP#GO:0005687;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000010296.3|UniProtKB=A0A2I2Z2V0 A0A2I2Z2V0 ARB2A PTHR21357:SF3 FAM172 FAMILY PROTEIN HOMOLOG CG10038 COTRANSCRIPTIONAL REGULATOR ARB2A binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulatory ncRNA-mediated heterochromatin formation#GO:0031048;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000041354.1|UniProtKB=A0A2I2Y733 A0A2I2Y733 LOC101130806 PTHR10369:SF44 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN L36A LIKE structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009954.3|UniProtKB=G3R399 G3R399 CASZ1 PTHR12451:SF0 TRANSCRIPTION FACTOR CASTOR PROTEIN MING -RELATED ZINC FINGER PROTEIN CASTOR HOMOLOG 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of neuron differentiation#GO:0045664;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000028247.2|UniProtKB=A0A2I2Z2I5 A0A2I2Z2I5 LOC101144910 PTHR24012:SF786 RNA BINDING PROTEIN RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000036332.1|UniProtKB=A0A2I2Z5Z0 A0A2I2Z5Z0 VAMP1 PTHR45701:SF1 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;binding#GO:0005488;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905;protein binding#GO:0005515 transport#GO:0006810;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;organelle organization#GO:0006996;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;localization#GO:0051179;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;vesicle fusion#GO:0006906 intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201 membrane traffic protein#PC00150 5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Synaptic vesicle trafficking#P05734>Synaptobrevin#P05779;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005 GORGO|Ensembl=ENSGGOG00000016637.3|UniProtKB=G3RKG6 G3RKG6 HSD17B2 PTHR43313:SF3 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular process#GO:0009987;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;hormone biosynthetic process#GO:0042446;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;regulation of biological quality#GO:0065008;steroid biosynthetic process#GO:0006694 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 GORGO|Ensembl=ENSGGOG00000015903.3|UniProtKB=G3RIK8 G3RIK8 FGF22 PTHR11486:SF41 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 22 signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104 nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000013813.3|UniProtKB=A0A2I2ZUT7 A0A2I2ZUT7 PTHR13491:SF0 ZCCHC10 PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10 GORGO|Ensembl=ENSGGOG00000016914.3|UniProtKB=G3RL70 G3RL70 PRKD3 PTHR22968:SF26 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE D3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PKC#P00565;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 GORGO|Ensembl=ENSGGOG00000000410.3|UniProtKB=A0A2I2ZVG5 A0A2I2ZVG5 DGKH PTHR11255:SF37 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000003953.3|UniProtKB=G3QMX9 G3QMX9 FIGLA PTHR23349:SF57 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FACTOR IN THE GERMLINE ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000004734.3|UniProtKB=G3QPY6 G3QPY6 MAP2K5 PTHR47238:SF4 MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000023645.2|UniProtKB=A0A2I2Y7F3 A0A2I2Y7F3 NAA40 PTHR20531:SF1 N-ALPHA-ACETYLTRANSFERASE 40 N-ALPHA-ACETYLTRANSFERASE 40 catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acyltransferase activity#GO:0140186;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000024522.2|UniProtKB=G3SHW7 G3SHW7 TNNC2 PTHR23064:SF72 TROPONIN TROPONIN C, SKELETAL MUSCLE actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000025194.2|UniProtKB=A0A2I2YLC7 A0A2I2YLC7 PTHR11963:SF38 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000013353.3|UniProtKB=G3RC10 G3RC10 SLC11A1 PTHR11706:SF52 SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 1 monoatomic cation transmembrane transporter activity#GO:0008324;iron ion transmembrane transporter activity#GO:0005381;transition metal ion transmembrane transporter activity#GO:0046915;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;iron ion transmembrane transport#GO:0034755;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic ion homeostasis#GO:0006873;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;metal ion transport#GO:0030001;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;iron ion transport#GO:0006826;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000015281.3|UniProtKB=A0A2I2YI47 A0A2I2YI47 PTHR14845:SF3 COILED-COIL DOMAIN-CONTAINING 166 COILED-COIL DOMAIN CONTAINING 121, RETROGENE 1 GORGO|Ensembl=ENSGGOG00000016662.3|UniProtKB=G3RKK6 G3RKK6 BLTP2 PTHR15678:SF6 ANTIGEN MLAA-22-RELATED BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2 GORGO|Ensembl=ENSGGOG00000002280.3|UniProtKB=G3QIM9 G3QIM9 STK19 PTHR15243:SF0 SERINE/THREONINE-PROTEIN KINASE 19 WINGED HELIX REPAIR FACTOR 1 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of cellular response to stress#GO:0080135;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000039786.1|UniProtKB=A0A2I2Y6W7 A0A2I2Y6W7 TSNAX PTHR10741:SF5 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN-ASSOCIATED PROTEIN X RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000023063.2|UniProtKB=G3RNT7 G3RNT7 TAAR2 PTHR24249:SF413 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000008652.3|UniProtKB=G3QZY2 G3QZY2 TTC23L PTHR14485:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 23 TETRATRICOPEPTIDE REPEAT PROTEIN 23-LIKE GORGO|Ensembl=ENSGGOG00000000625.3|UniProtKB=G3QEC4 G3QEC4 SLC26A11 PTHR11814:SF282 SULFATE TRANSPORTER SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006558.3|UniProtKB=G3QUL0 G3QUL0 CSN3 PTHR11470:SF2 KAPPA CASEIN KAPPA-CASEIN animal gross anatomical part developmental process#GO:0160108;transport#GO:0006810;developmental process#GO:0032502;secretion#GO:0046903;establishment of localization#GO:0051234;animal organ development#GO:0048513;anatomical structure development#GO:0048856;localization#GO:0051179;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647;regulation of body fluid levels#GO:0050878;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000007862.4|UniProtKB=G3QXX8 G3QXX8 RALGPS2 PTHR23113:SF357 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS2 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;Ras protein signal transduction#GO:0007265;regulation of signaling#GO:0023051;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000012051.3|UniProtKB=G3R8P9 G3R8P9 RSPH1 PTHR43215:SF18 RADIAL SPOKE HEAD 1 HOMOLOG RADIAL SPOKE HEAD 1 HOMOLOG cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;spermatogenesis#GO:0007283;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578 nucleus#GO:0005634;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000015005.3|UniProtKB=G3RGA1 G3RGA1 GRM1 PTHR24060:SF29 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066 cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell surface receptor signaling pathway#GO:0007166;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR 1/5#P01040;Endogenous cannabinoid signaling#P05730>mGluR#P05748;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Metabotropic glutamate receptor group I pathway#P00041>mGluR1#P01062;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Metabotropic glutamate receptor group I pathway#P00041>mGluR5#P01061 GORGO|Ensembl=ENSGGOG00000042553.1|UniProtKB=A0A2I2ZWU9 A0A2I2ZWU9 PTHR33560:SF2 PROTEIN FAM227B PROTEIN FAM227B GORGO|Ensembl=ENSGGOG00000024593.2|UniProtKB=A0A2I2Z3Y8 A0A2I2Z3Y8 RPS14 PTHR11759:SF72 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;translation#GO:0006412;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000037016.1|UniProtKB=A0A2I2YAT3 A0A2I2YAT3 LOC115930162 PTHR24264:SF62 TRYPSIN-RELATED TRYPSIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000015453.3|UniProtKB=A0A2I2ZT60 A0A2I2ZT60 NBEAL1 PTHR13743:SF115 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 1 membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008641.3|UniProtKB=G3S2B0 G3S2B0 UBOX5 PTHR13492:SF2 RING FINGER PROTEIN 37 RING FINGER PROTEIN 37 acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein ligase binding#GO:0044389;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin protein ligase binding#GO:0031625 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000042190.1|UniProtKB=A0A2I2ZBT7 A0A2I2ZBT7 PTHR16875:SF0 SELENOPROTEIN K SELENOPROTEIN K intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;homeostatic process#GO:0042592;regulation of calcium-mediated signaling#GO:0050848;regulation of intracellular signal transduction#GO:1902531;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;regulation of signaling#GO:0023051;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;regulation of response to stimulus#GO:0048583;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 GORGO|Ensembl=ENSGGOG00000028088.2|UniProtKB=G3SET4 G3SET4 ZNF668 PTHR24393:SF191 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 575 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000003405.3|UniProtKB=G3QLI9 G3QLI9 RSPH6A PTHR13159:SF1 RADIAL SPOKEHEAD-RELATED RADIAL SPOKE HEAD PROTEIN 6 HOMOLOG A organelle assembly#GO:0070925;cilium movement#GO:0003341;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036 ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000004015.4|UniProtKB=A0A2I2YFM7 A0A2I2YFM7 COL14A1 PTHR24020:SF15 COLLAGEN ALPHA COLLAGEN ALPHA-1(XIV) CHAIN extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;interstitial matrix#GO:0005614 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000001284.3|UniProtKB=A0A2I2YIE2 A0A2I2YIE2 SPATA6 PTHR16435:SF3 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488 developmental process involved in reproduction#GO:0003006;cilium assembly#GO:0060271;cellular component organization#GO:0016043;gamete generation#GO:0007276;cell projection organization#GO:0030030;reproductive process#GO:0022414;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;cilium organization#GO:0044782;multicellular organismal reproductive process#GO:0048609;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;male gamete generation#GO:0048232;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458 cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000025062.2|UniProtKB=G3SD32 G3SD32 CCNA1 PTHR10177:SF254 CYCLINS CYCLIN-A1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 GORGO|Ensembl=ENSGGOG00000043156.1|UniProtKB=A0A2I2YJC5 A0A2I2YJC5 PTHR23267:SF470 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 1-51 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000011750.3|UniProtKB=G3R7W3 G3R7W3 CHST10 PTHR12137:SF2 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 10 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000005377.3|UniProtKB=G3QRK9 G3QRK9 PPP1R35 PTHR28625:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of organelle organization#GO:0033043;regulation of cell projection assembly#GO:0060491;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;regulation of microtubule-based process#GO:0032886;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;positive regulation of cellular component biogenesis#GO:0044089;regulation of organelle assembly#GO:1902115;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;regulation of cilium assembly#GO:1902017 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000008080.3|UniProtKB=G3QYG3 G3QYG3 NKX2-2 PTHR24340:SF24 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000007037.3|UniProtKB=G3QVW2 G3QVW2 ATP13A5 PTHR45630:SF4 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE 13A5-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;polyamine transmembrane transporter activity#GO:0015203 transmembrane transport#GO:0055085;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic ion homeostasis#GO:0050801 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000006503.3|UniProtKB=G3QUG2 G3QUG2 EPHA7 PTHR46877:SF9 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 7 molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666 plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000039245.1|UniProtKB=A0A2I2YF05 A0A2I2YF05 SLC39A3 PTHR11040:SF221 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP3 transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000004981.3|UniProtKB=G3QQL3 G3QQL3 ZNF366 PTHR24390:SF268 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 366 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;nuclear estrogen receptor binding#GO:0030331;transcription corepressor activity#GO:0003714;nuclear receptor binding#GO:0016922 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000034845.2|UniProtKB=G3SKR6 G3SKR6 AKAP10 PTHR13155:SF1 A-KINASE ANCHOR PROTEINS A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 intracellular protein localization#GO:0008104;localization#GO:0051179;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006098.3|UniProtKB=G3QTE8 G3QTE8 MRPL14 PTHR21037:SF3 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000013701.3|UniProtKB=G3RCX0 G3RCX0 ZNF793 PTHR24381:SF455 ZINC FINGER PROTEIN RB-ASSOCIATED KRAB ZINC FINGER PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000006314.3|UniProtKB=G3QTY3 G3QTY3 HYAL4 PTHR11769:SF7 HYALURONIDASE HYALURONIDASE-4 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosaminoglycan catabolic process#GO:0006027;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosidase#PC00110 GORGO|Ensembl=ENSGGOG00000013188.3|UniProtKB=G3RBK9 G3RBK9 STK32C PTHR24356:SF153 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 32C catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000023680.2|UniProtKB=A0A2I2Y451 A0A2I2Y451 PTHR23105:SF189 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN EL8 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000027685.2|UniProtKB=A0A2I2YA36 A0A2I2YA36 PTHR10544:SF12 60S RIBOSOMAL PROTEIN L28 LARGE RIBOSOMAL SUBUNIT PROTEIN EL28 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025071.2|UniProtKB=G3SKA6 G3SKA6 FERRY3 PTHR16525:SF0 PROTEIN C12ORF4 FERRY ENDOSOMAL RAB5 EFFECTOR COMPLEX SUBUNIT 3 regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of vesicle-mediated transport#GO:0060627;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of immune effector process#GO:0002697;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000015824.3|UniProtKB=G3SF08 G3SF08 PPM1M PTHR13832:SF236 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1M catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000015890.3|UniProtKB=G3RWW0 G3RWW0 LOC101138809 PTHR11771:SF34 LIPOXYGENASE POLYUNSATURATED FATTY ACID (12S)_(13S)-LIPOXYGENASE, EPIDERMAL-TYPE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;arachidonate metabolic process#GO:0019369;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;icosanoid metabolic process#GO:0006690 cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 GORGO|Ensembl=ENSGGOG00000012076.3|UniProtKB=G3R8Q7 G3R8Q7 LOC101137485 PTHR11691:SF37 TYPE I INTERFERON INTERFERON OMEGA-1 protein binding#GO:0005515;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;cytokine activity#GO:0005125;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;T cell activation#GO:0042110;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312;immune system process#GO:0002376;defense response to other organism#GO:0098542;lymphocyte activation#GO:0046649;response to chemical#GO:0042221;response to cytokine#GO:0034097;T cell activation involved in immune response#GO:0002286;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;lymphocyte activation involved in immune response#GO:0002285;signal transduction#GO:0007165;B cell activation#GO:0042113;humoral immune response#GO:0006959;leukocyte activation involved in immune response#GO:0002366;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;natural killer cell activation#GO:0030101;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cytokine-mediated signaling pathway#GO:0019221;cell activation#GO:0001775;multicellular organismal process#GO:0032501;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;immune response#GO:0006955;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;interferon superfamily#PC00127 GORGO|Ensembl=ENSGGOG00000015090.3|UniProtKB=G3RGH9 G3RGH9 TAC3 PTHR15536:SF1 TACHYKININ-3 TACHYKININ-3 circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;system process#GO:0003008;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of blood pressure#GO:0045777;blood circulation#GO:0008015 GORGO|Ensembl=ENSGGOG00000036178.1|UniProtKB=A0A2I2Y4J1 A0A2I2Y4J1 PTHR23266:SF410 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-46 binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000023324.2|UniProtKB=G3RVW9 G3RVW9 PTHR11545:SF36 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 negative regulation of translation#GO:0017148;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000000008.3|UniProtKB=G3QCR4 G3QCR4 OTOF PTHR12546:SF32 FER-1-LIKE OTOFERLIN metal ion binding#GO:0046872;protein-containing complex binding#GO:0044877;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 synaptic vesicle recycling#GO:0036465;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;neurotransmitter secretion#GO:0007269;response to mechanical stimulus#GO:0009612;establishment of localization#GO:0051234;response to external stimulus#GO:0009605;system process#GO:0003008;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;response to stimulus#GO:0050896;sensory perception of sound#GO:0007605;export from cell#GO:0140352;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;plasma membrane organization#GO:0007009;cellular localization#GO:0051641;secretion by cell#GO:0032940;nervous system process#GO:0050877 secretory vesicle#GO:0099503;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;organelle membrane#GO:0031090;presynaptic active zone membrane#GO:0048787;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000015823.3|UniProtKB=G3RWV5 G3RWV5 NAA16 PTHR22767:SF5 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 16, NATA AUXILIARY SUBUNIT molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493 acetyltransferase#PC00038 GORGO|Ensembl=ENSGGOG00000006941.3|UniProtKB=A0A2I2YBP2 A0A2I2YBP2 TP53I11 PTHR31584:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 GORGO|Ensembl=ENSGGOG00000016688.3|UniProtKB=G3RKN0 G3RKN0 SUPT6H PTHR10145:SF6 TRANSCRIPTION ELONGATION FACTOR SPT6 TRANSCRIPTION ELONGATION FACTOR SPT6 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006623.3|UniProtKB=G3QUS3 G3QUS3 YJU2B PTHR12111:SF2 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2B-RELATED ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000002516.3|UniProtKB=G3QJ92 G3QJ92 MAD2L1 PTHR11842:SF13 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;negative regulation of chromosome separation#GO:1905819;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of cell cycle#GO:0045786;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;negative regulation of chromosome segregation#GO:0051985 condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687 GORGO|Ensembl=ENSGGOG00000012554.3|UniProtKB=A0A2I2YLW6 A0A2I2YLW6 PGAP2 PTHR12892:SF11 FGF RECEPTOR ACTIVATING PROTEIN 1 ACYLTRANSFERASE PGAP2 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011362.3|UniProtKB=G3R6V7 G3R6V7 ZNF28 PTHR24377:SF301 IP01015P-RELATED ZINC FINGER PROTEIN 28 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000002824.3|UniProtKB=G3QK18 G3QK18 ASB14 PTHR24133:SF60 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT AND SOCS BOX-CONTAINING 3 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002070.3|UniProtKB=G3RR25 G3RR25 SLF2 PTHR16046:SF10 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR 2 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 2 response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;positive regulation of double-strand break repair#GO:2000781;positive regulation of DNA metabolic process#GO:0051054;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cellular response to stimulus#GO:0051716;localization#GO:0051179;positive regulation of metabolic process#GO:0009893;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;cellular response to stress#GO:0033554;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;intracellular protein localization#GO:0008104;regulation of response to stress#GO:0080134;DNA damage response#GO:0006974;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583 site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734 GORGO|Ensembl=ENSGGOG00000042591.1|UniProtKB=A0A2I2YK58 A0A2I2YK58 PTHR33166:SF11 GAG_P30 DOMAIN-CONTAINING PROTEIN CORE SHELL PROTEIN GAG P30 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000012883.3|UniProtKB=G3RAU1 G3RAU1 SLA2 PTHR10155:SF6 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SRC-LIKE-ADAPTER 2 enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;cellular response to chemical stimulus#GO:0070887 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;extrinsic component of membrane#GO:0019898;membrane protein complex#GO:0098796;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 kinase modulator#PC00140 Interleukin signaling pathway#P00036>Src-like#P00991 GORGO|Ensembl=ENSGGOG00000034893.2|UniProtKB=A0A2I2YJD4 A0A2I2YJD4 PTHR10909:SF378 ELECTRON TRANSPORT OXIDOREDUCTASE ACYL-COENZYME A OXIDASE-LIKE PROTEIN fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;lipid binding#GO:0008289;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;organic acid binding#GO:0043177;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824 lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000011350.3|UniProtKB=G3R6U2 G3R6U2 ADAM29 PTHR11905:SF34 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 29 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000003840.3|UniProtKB=G3QMM7 G3QMM7 LOC101141577 PTHR26453:SF78 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T27-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000023118.2|UniProtKB=G3SDM7 G3SDM7 GIN1 PTHR47266:SF6 ENDONUCLEASE-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 GORGO|Ensembl=ENSGGOG00000002447.3|UniProtKB=G3QJ28 G3QJ28 XAB2 PTHR11246:SF5 PRE-MRNA SPLICING FACTOR PRE-MRNA-SPLICING FACTOR SYF1 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000034882.2|UniProtKB=A0A2I2YIV6 A0A2I2YIV6 TMEM209 PTHR21780:SF0 TRANSMEMBRANE PROTEIN 209 TRANSMEMBRANE PROTEIN 209 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000007747.3|UniProtKB=A0A2I2ZDJ8 A0A2I2ZDJ8 PTHR23415:SF32 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 HOMOLOG cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039142.1|UniProtKB=A0A2I2YSM4 A0A2I2YSM4 PTHR48026:SF17 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN RRM DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000043434.1|UniProtKB=A0A2I2YS08 A0A2I2YS08 LOC101147269 PTHR12756:SF9 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 6 cytoskeletal protein binding#GO:0008092;metalloexopeptidase activity#GO:0008235;tubulin binding#GO:0015631;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;binding#GO:0005488;carboxypeptidase activity#GO:0004180;metallocarboxypeptidase activity#GO:0004181;protein binding#GO:0005515;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000004655.3|UniProtKB=G3QPR2 G3QPR2 TAPBPL PTHR23411:SF18 TAPASIN TAPASIN-RELATED PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 antigen processing and presentation#GO:0019882;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;immune system process#GO:0002376;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000034900.2|UniProtKB=A0A2I2YQX1 A0A2I2YQX1 KIF16B PTHR47117:SF8 STAR-RELATED LIPID TRANSFER PROTEIN 9 KINESIN-LIKE PROTEIN KIF16B ISOFORM X1 GORGO|Ensembl=ENSGGOG00000041082.1|UniProtKB=A0A2I2Z1I5 A0A2I2Z1I5 ATP6V1G1 PTHR12713:SF12 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G 1 homeostatic process#GO:0042592;cellular component organization#GO:0016043;monoatomic ion transport#GO:0006811;cellular localization#GO:0051641;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;vesicle-mediated transport#GO:0016192;developmental maturation#GO:0021700;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cellular homeostasis#GO:0019725;vesicle organization#GO:0016050;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;proton transmembrane transport#GO:1902600;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;developmental process#GO:0032502 cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell junction#GO:0030054;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular vesicle#GO:0097708;ATPase dependent transmembrane transport complex#GO:0098533;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000006685.3|UniProtKB=A0A2I2YTD4 A0A2I2YTD4 POSTN PTHR10900:SF12 PERIOSTIN-RELATED PERIOSTIN protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cell adhesion#GO:0007155 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000003567.3|UniProtKB=G3QLY3 G3QLY3 ARL13B PTHR46090:SF3 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;organelle assembly#GO:0070925;localization within membrane#GO:0051668;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cellular localization#GO:0051641;cilium organization#GO:0044782;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;plasma membrane region#GO:0098590;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cell projection membrane#GO:0031253;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011744.3|UniProtKB=A0A2I2ZAN0 A0A2I2ZAN0 NSD1 PTHR22884:SF312 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 SPECIFIC catalytic activity, acting on a protein#GO:0140096;histone H3K36 methyltransferase activity#GO:0046975;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000026552.2|UniProtKB=G3RYC9 G3RYC9 HECTD1 PTHR45670:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE HECTD1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000013024.3|UniProtKB=G3RB66 G3RB66 PEA15 PTHR48169:SF1 DED DOMAIN-CONTAINING PROTEIN ASTROCYTIC PHOSPHOPROTEIN PEA-15 regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 Gonadotropin-releasing hormone receptor pathway#P06664>PEA-15#P06853 GORGO|Ensembl=ENSGGOG00000027696.2|UniProtKB=A0A2I2ZG88 A0A2I2ZG88 PTHR15361:SF7 RAD51/NUKS-INTERACTING PROTEIN RAD51 INTERACTING MOTIF DOMAIN-CONTAINING PROTEIN single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 GORGO|Ensembl=ENSGGOG00000008123.3|UniProtKB=G3QYL0 G3QYL0 PTCH1 PTHR46022:SF5 PROTEIN PATCHED PROTEIN PATCHED HOMOLOG 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 Hedgehog signaling pathway#P00025>Patched#P00689 GORGO|Ensembl=ENSGGOG00000008007.3|UniProtKB=G3QYA2 G3QYA2 MLYCD PTHR28641:SF1 FAMILY NOT NAMED MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL GORGO|Ensembl=ENSGGOG00000006152.3|UniProtKB=G3S2B8 G3S2B8 THAP12 PTHR46289:SF16 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE GORGO|Ensembl=ENSGGOG00000009107.3|UniProtKB=G3R148 G3R148 DEDD2 PTHR15205:SF1 DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN DNA-BINDING DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN 2 programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;apoptotic signaling pathway#GO:0097190;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000009946.3|UniProtKB=G3R390 G3R390 FAM151A PTHR21184:SF4 MENORIN (DENDRITIC BRANCHING PROTEIN) PROTEIN FAM151A cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 GORGO|Ensembl=ENSGGOG00000004920.3|UniProtKB=A0A2I2Z937 A0A2I2Z937 PTHR45620:SF19 PDF RECEPTOR-LIKE PROTEIN-RELATED CORTICOTROPIN-RELEASING HORMONE RECEPTOR 2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of biological quality#GO:0065008;positive regulation of synaptic transmission#GO:0050806;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of synaptic plasticity#GO:0048167;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell junction#GO:0030054;axon terminus#GO:0043679;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;neuron projection#GO:0043005;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron projection terminus#GO:0044306;cell projection#GO:0042995 transmembrane signal receptor#PC00197 Cortocotropin releasing factor receptor signaling pathway#P04380>CRHR1#P04451 GORGO|Ensembl=ENSGGOG00000001057.3|UniProtKB=G3RRE0 G3RRE0 NRBP1 PTHR13902:SF48 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000039414.1|UniProtKB=A0A2I2YZM5 A0A2I2YZM5 PTHR10219:SF79 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN transporter activity#GO:0005215;phospholipid binding#GO:0005543;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;ion binding#GO:0043167;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;transport#GO:0006810;lipid localization#GO:0010876;membrane organization#GO:0061024;ceramide transport#GO:0035627;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000010999.3|UniProtKB=G3R5Y6 G3R5Y6 CIMAP1B PTHR21580:SF19 SHIPPO-1-RELATED CILIARY MICROTUBULE ASSOCIATED PROTEIN 1B sperm motility#GO:0097722;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000024027.2|UniProtKB=G3RNB7 G3RNB7 LOC101145839 PTHR12305:SF102 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;system development#GO:0048731;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;vasculature development#GO:0001944;multicellular organism development#GO:0007275;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;protein phosphatase#PC00195 PI3 kinase pathway#P00048>PTEN#P01189;p53 pathway#P00059>PTEN#P01480;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway feedback loops 2#P04398>PTEN#P04658;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;p53 pathway feedback loops 2#P04398>PTEN#G04714;CCKR signaling map#P06959>PTEN#P07071;Hypoxia response via HIF activation#P00030>PTEN#P00824;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PTEN#P00849;p53 pathway#P00059>PTEN#G01579 GORGO|Ensembl=ENSGGOG00000002079.3|UniProtKB=A0A2I2ZQ02 A0A2I2ZQ02 DNAJB11 PTHR44298:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 protein binding#GO:0005515;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000015496.3|UniProtKB=G3RMX3 G3RMX3 MMP12 PTHR10201:SF267 MATRIX METALLOPROTEINASE MACROPHAGE METALLOELASTASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 GORGO|Ensembl=ENSGGOG00000014341.3|UniProtKB=G3REL0 G3REL0 LMBRD1 PTHR16130:SF3 LYSOSOMAL COBALAMIN TRANSPORTER-RELATED LYSOSOMAL COBALAMIN TRANSPORT ESCORT PROTEIN LMBD1 protein localization to lysosome#GO:0061462;macromolecule localization#GO:0033036;protein localization to vacuole#GO:0072665;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000000457.3|UniProtKB=G3QDX0 G3QDX0 KRT10 PTHR23239:SF137 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 10 structural molecule activity#GO:0005198 intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament-based process#GO:0045103;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cellular process#GO:0009987;organelle organization#GO:0006996;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;epidermis development#GO:0008544 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000006166.3|UniProtKB=G3QTL1 G3QTL1 SEC24C PTHR13803:SF5 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24C zinc ion binding#GO:0008270;SNARE binding#GO:0000149;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 COPII-coated vesicle budding#GO:0090114;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024 vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated membrane#GO:0048475;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vesicle coat#GO:0030120;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000002765.3|UniProtKB=A0A2I2Z333 A0A2I2Z333 GARIN4 PTHR22574:SF15 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 4 GORGO|Ensembl=ENSGGOG00000004739.3|UniProtKB=G3QPY0 G3QPY0 SCART1 PTHR19331:SF458 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN SCART1 cargo receptor activity#GO:0038024 hemopoiesis#GO:0030097;T cell differentiation#GO:0030217;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;cellular process#GO:0009987;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell development#GO:0048468;cell differentiation#GO:0030154;mononuclear cell differentiation#GO:1903131;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;leukocyte activation#GO:0045321;cell fate commitment#GO:0045165;anatomical structure development#GO:0048856;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;immune system process#GO:0002376 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000005610.3|UniProtKB=G3QS66 G3QS66 WDFY1 PTHR46189:SF2 LD41958P WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 1 positive regulation of signaling#GO:0023056;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;regulation of intracellular signal transduction#GO:1902531;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of response to external stimulus#GO:0032103;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to external stimulus#GO:0032101;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of immune system process#GO:0002684 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000041687.1|UniProtKB=A0A2I2ZLP7 A0A2I2ZLP7 PTHR10562:SF74 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 3 protein binding#GO:0005515;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 p53 pathway#P00059>Sumo-1 ligase#P04635 GORGO|Ensembl=ENSGGOG00000016986.3|UniProtKB=G3SIK5 G3SIK5 PTHR23068:SF6 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED PWWP DOMAIN-CONTAINING PROTEIN 2B nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA methyltransferase#PC00013 GORGO|Ensembl=ENSGGOG00000017168.3|UniProtKB=A0A2I2Z4L1 A0A2I2Z4L1 AIF1L PTHR10356:SF5 ALLOGRAFT INFLAMMATORY FACTOR-1 ALLOGRAFT INFLAMMATORY FACTOR 1-LIKE cytoskeletal protein binding#GO:0008092;protein-containing complex binding#GO:0044877;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;actin filament binding#GO:0051015;actin binding#GO:0003779;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cell projection membrane#GO:0031253;intracellular organelle#GO:0043229;leading edge membrane#GO:0031256;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;polymeric cytoskeletal fiber#GO:0099513;ruffle#GO:0001726;membraneless organelle#GO:0043228;actin filament#GO:0005884;cytoskeleton#GO:0005856;ruffle membrane#GO:0032587;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252 calcium-binding protein#PC00060;calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000042803.1|UniProtKB=A0A2I2YMI2 A0A2I2YMI2 PTHR11991:SF10 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN HOMOLOG small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;negative regulation of programmed cell death#GO:0043069;negative regulation of cell communication#GO:0010648;negative regulation of catabolic process#GO:0009895;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000013639.3|UniProtKB=G3RCS4 G3RCS4 CRYBB1 PTHR11818:SF12 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B1 structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory system development#GO:0048880;multicellular organismal process#GO:0032501 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000006662.3|UniProtKB=G3RQ23 G3RQ23 ALPK1 PTHR46747:SF1 ALPHA-PROTEIN KINASE 1 ALPHA-PROTEIN KINASE 1 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000042091.1|UniProtKB=A0A2I2YIQ1 A0A2I2YIQ1 ZNF564 PTHR24381:SF446 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 555 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009155.3|UniProtKB=G3R190 G3R190 ZNF804A PTHR17614:SF13 ZINC FINGER-CONTAINING ZINC FINGER PROTEIN 804A organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000042668.1|UniProtKB=A0A2I2Y7C2 A0A2I2Y7C2 POLDIP2 PTHR14289:SF16 F-BOX ONLY PROTEIN 3 POLYMERASE DELTA-INTERACTING PROTEIN 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 macromolecule metabolic process#GO:0043170;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nucleoid#GO:0009295;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrial nucleoid#GO:0042645;mitochondrion#GO:0005739;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000000517.3|UniProtKB=G3QE27 G3QE27 BDP1 PTHR22929:SF0 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' HOMOLOG RNA metabolism protein#PC00031;general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000009382.3|UniProtKB=G3R1T8 G3R1T8 HAUS8 PTHR31807:SF37 AUGMIN FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 8 GORGO|Ensembl=ENSGGOG00000043061.1|UniProtKB=A0A2I2Z1C9 A0A2I2Z1C9 PTHR23341:SF5 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP AT-HOOK PROTEIN 1 DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488 cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000022499.2|UniProtKB=G3SAT0 G3SAT0 PTHR46949:SF3 LEUCINE REPEAT ADAPTER PROTEIN 25 PROTEIN FAM89A scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007142.3|UniProtKB=G3QW39 G3QW39 TRPC4 PTHR10117:SF25 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 GORGO|Ensembl=ENSGGOG00000012118.3|UniProtKB=G3R8V3 G3R8V3 SLC17A2 PTHR11662:SF193 SOLUTE CARRIER FAMILY 17 SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000013502.3|UniProtKB=G3RCG3 G3RCG3 MYO5C PTHR13140:SF313 MYOSIN UNCONVENTIONAL MYOSIN-VC isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000016379.3|UniProtKB=G3RJT3 G3RJT3 TRIM15 PTHR24103:SF259 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM15 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000025962.2|UniProtKB=G3S923 G3S923 CCDC92 PTHR14882:SF4 COILED-COIL DOMAIN-CONTAINING 74A COILED-COIL DOMAIN-CONTAINING PROTEIN 92 positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of innate immune response#GO:0045088;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;intracellular receptor signaling pathway#GO:0030522;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;inflammatory response#GO:0006954;regulation of defense response#GO:0031347;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular component assembly#GO:0022607;regulation of response to external stimulus#GO:0032101;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000006201.3|UniProtKB=G3SCK8 G3SCK8 OBP2A PTHR11430:SF140 LIPOCALIN ODORANT BINDING PROTEIN 2A extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000013897.3|UniProtKB=G3SFK8 G3SFK8 KMO PTHR46028:SF2 KYNURENINE 3-MONOOXYGENASE KYNURENINE 3-MONOOXYGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000010214.3|UniProtKB=G3R3Z3 G3R3Z3 CEMIP2 PTHR15535:SF26 TRANSMEMBRANE PROTEIN 2-RELATED CELL SURFACE HYALURONIDASE CEMIP2 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;glycosaminoglycan catabolic process#GO:0006027;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosaminoglycan metabolic process#GO:0030203 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000003561.3|UniProtKB=G3QLX8 G3QLX8 WDR47 PTHR19863:SF5 NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG WD REPEAT-CONTAINING PROTEIN 47 GORGO|Ensembl=ENSGGOG00000026790.2|UniProtKB=G3RXK5 G3RXK5 PRDX4 PTHR10681:SF180 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-4 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 cellular process#GO:0009987;response to stress#GO:0006950;homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;catabolic process#GO:0009056;response to stimulus#GO:0050896;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to oxidative stress#GO:0006979 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000014015.3|UniProtKB=A0A2I2ZHA2 A0A2I2ZHA2 AMPD3 PTHR11359:SF2 AMP DEAMINASE AMP DEAMINASE 3 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239 organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390 deaminase#PC00088 Purine metabolism#P02769>5'-AMP Deaminase#P03117 GORGO|Ensembl=ENSGGOG00000037392.1|UniProtKB=A0A2I2YDX4 A0A2I2YDX4 SUN2 PTHR12911:SF22 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;membrane#GO:0016020 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000008615.3|UniProtKB=G3QZV4 G3QZV4 ZNF704 PTHR13006:SF7 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 ZINC FINGER PROTEIN 704 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000015151.3|UniProtKB=A0A2I2YT51 A0A2I2YT51 ZNF133 PTHR24393:SF191 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 575 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000000125.3|UniProtKB=G3S6Q2 G3S6Q2 LOC101145339 PTHR42687:SF1 L-THREONINE 3-DEHYDROGENASE L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000006247.3|UniProtKB=G3QTS5 G3QTS5 CD83 PTHR15193:SF1 CD83 ANTIGEN CD83 ANTIGEN GORGO|Ensembl=ENSGGOG00000037028.1|UniProtKB=A0A2I2YAE0 A0A2I2YAE0 CD300H PTHR11860:SF117 POLYMERIC-IMMUNOGLOBULIN RECEPTOR PROTEIN CD300H transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of innate immune response#GO:0045088;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of response to biotic stimulus#GO:0002831;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000028100.2|UniProtKB=G3QS82 G3QS82 LOC101143900 PTHR20515:SF3 BETA-DEFENSIN BETA-DEFENSIN 109B molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;locomotion#GO:0040011;response to bacterium#GO:0009617;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;defense response to bacterium#GO:0042742;cell chemotaxis#GO:0060326;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;response to other organism#GO:0051707;response to external stimulus#GO:0009605;defense response#GO:0006952 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014099.3|UniProtKB=G3RDZ4 G3RDZ4 LHX3 PTHR24208:SF91 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000025685.2|UniProtKB=G3RX74 G3RX74 GLO1 PTHR10374:SF30 LACTOYLGLUTATHIONE LYASE GLYOXALASE I LACTOYLGLUTATHIONE LYASE metabolite interconversion enzyme#PC00262;lyase#PC00144 GORGO|Ensembl=ENSGGOG00000003058.3|UniProtKB=G3QKP2 G3QKP2 UBR5 PTHR46276:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR5 E3 UBIQUITIN-PROTEIN LIGASE UBR5 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 macromolecule metabolic process#GO:0043170;positive regulation of canonical Wnt signaling pathway#GO:0090263;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;protein ubiquitination#GO:0016567;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;macromolecule modification#GO:0043412;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 Hedgehog signaling pathway#P00025>Ubiquitin ligase#P00693 GORGO|Ensembl=ENSGGOG00000027597.2|UniProtKB=A0A2I2ZF32 A0A2I2ZF32 LOC101153347 PTHR11937:SF590 ACTIN ACTIN, BETA binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell motility#GO:0048870;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 neuron projection#GO:0043005;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin filament#GO:0005884;cell junction#GO:0030054;histone acetyltransferase complex#GO:0000123;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;supramolecular fiber#GO:0099512;membrane#GO:0016020;H4 histone acetyltransferase complex#GO:1902562;cytoskeleton#GO:0005856;transferase complex#GO:1990234;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cadherin signaling pathway#P00012>F-actin#P00470 GORGO|Ensembl=ENSGGOG00000034946.2|UniProtKB=A0A2I2ZYN1 A0A2I2ZYN1 LOC101154316 PTHR24033:SF232 EGF-LIKE DOMAIN-CONTAINING PROTEIN PROTEIN EYES SHUT HOMOLOG extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013949.3|UniProtKB=G3RDJ8 G3RDJ8 GLRA4 PTHR18945:SF211 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-4 monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810 cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;organelle#GO:0043226;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000002115.3|UniProtKB=G3QI77 G3QI77 MYOG PTHR11534:SF5 MYOGENIC FACTOR MYOGENIN transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;animal organ development#GO:0048513;muscle organ development#GO:0007517;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell differentiation#GO:0045597;striated muscle tissue development#GO:0014706;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;positive regulation of DNA-templated transcription#GO:0045893;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;skeletal muscle tissue development#GO:0007519;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016828.3|UniProtKB=G3RKY3 G3RKY3 U2AF1L4 PTHR12620:SF3 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT SPLICING FACTOR U2AF 26 KDA SUBUNIT RNA binding#GO:0003723;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002;binding#GO:0005488 gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000005753.3|UniProtKB=G3QSK0 G3QSK0 CLOCK PTHR46055:SF2 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;rhythmic process#GO:0048511;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 Circadian clock system#P00015>Clock#P00501 GORGO|Ensembl=ENSGGOG00000007273.3|UniProtKB=G3QWH2 G3QWH2 CEP162 PTHR34031:SF1 CENTROSOMAL PROTEIN OF 162 KDA CENTROSOMAL PROTEIN OF 162 KDA cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule#GO:0005874;axoneme#GO:0005930;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic microtubule#GO:0005881;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;nuclear lumen#GO:0031981;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000012335.3|UniProtKB=G3R9F8 G3R9F8 PHF12 PTHR46309:SF28 PHD FINGER PROTEIN 12 PHD FINGER PROTEIN 12 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000022721.2|UniProtKB=A0A2I2YCH7 A0A2I2YCH7 PTHR12000:SF36 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;catabolic process#GO:0009056;biosynthetic process#GO:0009058;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteolysis#GO:0006508;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000037449.1|UniProtKB=A0A2I2ZF74 A0A2I2ZF74 LOC101125875 PTHR24377:SF848 IP01015P-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016600.3|UniProtKB=G3RKD6 G3RKD6 TRIM66 PTHR45915:SF7 TRANSCRIPTION INTERMEDIARY FACTOR TRIPARTITE MOTIF-CONTAINING PROTEIN 66 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000000449.3|UniProtKB=G3QDW1 G3QDW1 SLC49A4 PTHR10924:SF27 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER 4 intracellular organelle#GO:0043229;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000043096.1|UniProtKB=A0A2I2Z6T5 A0A2I2Z6T5 PTHR11652:SF46 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006274.3|UniProtKB=G3QTW0 G3QTW0 TTC31 PTHR47678:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 31 TETRATRICOPEPTIDE REPEAT PROTEIN 31 GORGO|Ensembl=ENSGGOG00000004360.3|UniProtKB=G3RX51 G3RX51 ELK4 PTHR11849:SF21 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-4 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>ELK#P01140;CCKR signaling map#P06959>SAP1#P07097;Interleukin signaling pathway#P00036>ELK#P00962 GORGO|Ensembl=ENSGGOG00000023817.2|UniProtKB=A0A2I2YJF0 A0A2I2YJF0 PTHR44006:SF1 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 mRNA splicing#P00058>U5#P01474 GORGO|Ensembl=ENSGGOG00000014492.3|UniProtKB=G3REX9 G3REX9 LOC101152596 PTHR17130:SF14 MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011140.3|UniProtKB=G3R6B5 G3R6B5 ZNF785 PTHR24381:SF297 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 785 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000040927.1|UniProtKB=P56439 P56439 CCR5 PTHR10489:SF960 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 5 cytokine receptor activity#GO:0004896;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;locomotion#GO:0040011;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;calcium-mediated signaling#GO:0019722;defense response#GO:0006952;response to external stimulus#GO:0009605;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;response to stress#GO:0006950 intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000008314.3|UniProtKB=G3QZ32 G3QZ32 DDX31 PTHR24031:SF89 RNA HELICASE ATP-DEPENDENT DNA HELICASE DDX31 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000005936.3|UniProtKB=G3S4D0 G3S4D0 CEACAM1 PTHR44427:SF1 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM1 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000015130.3|UniProtKB=G3RGL5 G3RGL5 PROX1 PTHR12198:SF6 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 PROSPERO HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000005195.3|UniProtKB=G3QR54 G3QR54 RSL24D1 PTHR10792:SF26 60S RIBOSOMAL PROTEIN L24 RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025438.2|UniProtKB=G3SJL4 G3SJL4 CLDN7 PTHR12002:SF78 CLAUDIN CLAUDIN-7 cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000027941.2|UniProtKB=G3SIB9 G3SIB9 LOC101134267 PTHR26450:SF194 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000003006.3|UniProtKB=G3QKI3 G3QKI3 IL12RB1 PTHR23036:SF51 CYTOKINE RECEPTOR INTERLEUKIN-12 RECEPTOR SUBUNIT BETA-1 cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;response to peptide#GO:1901652;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 GORGO|Ensembl=ENSGGOG00000001405.3|UniProtKB=A0A2I2ZYG2 A0A2I2ZYG2 MPHOSPH6 PTHR13582:SF0 M-PHASE PHOSPHOPROTEIN 6 M-PHASE PHOSPHOPROTEIN 6 ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000001341.3|UniProtKB=G3QG73 G3QG73 HOXD10 PTHR45874:SF5 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-D10 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000003423.3|UniProtKB=A0A2I2ZMW2 A0A2I2ZMW2 DNPEP PTHR28570:SF18 ASPARTYL AMINOPEPTIDASE ASPARTYL AMINOPEPTIDASE catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000014061.3|UniProtKB=G3RDW1 G3RDW1 ELMO2 PTHR12771:SF8 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 2 response to external stimulus#GO:0009605;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;chemotaxis#GO:0006935;actin filament-based process#GO:0030029;cellular response to chemical stimulus#GO:0070887;supramolecular fiber organization#GO:0097435;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;locomotion#GO:0040011;response to stimulus#GO:0050896;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>ELMO#P00917 GORGO|Ensembl=ENSGGOG00000012636.3|UniProtKB=A0A2I2Y9H0 A0A2I2Y9H0 GHR PTHR23036:SF108 CYTOKINE RECEPTOR GROWTH HORMONE RECEPTOR molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;positive regulation of cellular process#GO:0048522;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to nitrogen compound#GO:1901698;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of receptor signaling pathway via STAT#GO:1904892;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway#GO:0007166;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052 signaling receptor complex#GO:0043235;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000023145.2|UniProtKB=A0A2I2YB08 A0A2I2YB08 LOC101139367 PTHR10454:SF13 CASPASE CASPASE-4 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197 apoptotic process#GO:0006915;cell death#GO:0008219;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;inflammatory response#GO:0006954;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;regulation of neuron apoptotic process#GO:0043523;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;positive regulation of response to stimulus#GO:0048584;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;positive regulation of inflammatory response#GO:0050729;positive regulation of neuron apoptotic process#GO:0043525;defense response#GO:0006952;positive regulation of response to external stimulus#GO:0032103;positive regulation of apoptotic process#GO:0043065 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;canonical inflammasome complex#GO:0061702;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000003952.3|UniProtKB=A0A2I2ZSW3 A0A2I2ZSW3 PMPCB PTHR11851:SF103 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104 mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;endopeptidase complex#GO:1905369 protease#PC00190;metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000001601.3|UniProtKB=G3QGW3 G3QGW3 ATP6V1D PTHR11671:SF5 V-TYPE ATP SYNTHASE SUBUNIT D V-TYPE PROTON ATPASE SUBUNIT D transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324 vacuolar acidification#GO:0007035;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of intracellular pH#GO:0051453;homeostatic process#GO:0042592;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873 proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000013505.3|UniProtKB=G3RCE3 G3RCE3 POP5 PTHR48414:SF1 POP5 HOMOLOG, RIBONUCLEASE P_MRP SUBUNIT RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle lumen#GO:0043233;nucleolar ribonuclease P complex#GO:0005655;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;multimeric ribonuclease P complex#GO:0030681;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000002309.3|UniProtKB=G3QIQ8 G3QIQ8 DIMT1 PTHR11727:SF34 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000004913.3|UniProtKB=G3QQE7 G3QQE7 HOOK3 PTHR18947:SF38 HOOK PROTEINS PROTEIN HOOK HOMOLOG 3 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 cytoplasmic microtubule organization#GO:0031122;cellular component organization#GO:0016043;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000040198.1|UniProtKB=G3R4T1 G3R4T1 PTHR23262:SF175 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-3 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000004097.3|UniProtKB=G3QNA9 G3QNA9 PRPH2 PTHR19282:SF202 TETRASPANIN PERIPHERIN-2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006065.3|UniProtKB=A0A2I2ZSP6 A0A2I2ZSP6 NAE1 PTHR10953:SF29 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000042656.1|UniProtKB=A0A2I2YMX2 A0A2I2YMX2 TSSK6 PTHR24343:SF166 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 6 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular process#GO:0009987;male gamete generation#GO:0048232;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006830.3|UniProtKB=G3QVC0 G3QVC0 CCDC117 PTHR36128:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 117 COILED-COIL DOMAIN-CONTAINING PROTEIN 117 GORGO|Ensembl=ENSGGOG00000003755.3|UniProtKB=G3QMF0 G3QMF0 DYDC2 PTHR23356:SF3 DPY30-RELATED DPY30 DOMAIN-CONTAINING PROTEIN 2 membraneless organelle#GO:0043228;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000006078.3|UniProtKB=G3QTD5 G3QTD5 ZNF330 PTHR13214:SF1 ZINC FINGER PROTEIN 330 ZINC FINGER PROTEIN 330 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000016925.3|UniProtKB=G3RL75 G3RL75 PTHR24334:SF2 HOMEOBOX PROTEIN GBX HOMEOBOX PROTEIN GBX-1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000008769.3|UniProtKB=G3SCY1 G3SCY1 CLDN15 PTHR12002:SF74 CLAUDIN CLAUDIN-15 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 cellular process#GO:0009987;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;transport#GO:0006810;paracellular transport#GO:0160184;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 GORGO|Ensembl=ENSGGOG00000000443.3|UniProtKB=G3QDV8 G3QDV8 MTTP PTHR13024:SF1 MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN, LARGE SUBUNIT MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN LARGE SUBUNIT cellular process#GO:0009987;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;lipoprotein metabolic process#GO:0042157;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cholesterol homeostasis#GO:0042632;protein metabolic process#GO:0019538 basal part of cell#GO:0045178;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000023987.2|UniProtKB=G3S9H2 G3S9H2 NRSN1 PTHR14796:SF6 NEURENSIN 1-RELATED NEURENSIN-1 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731 somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;neuron projection#GO:0043005;neuronal cell body#GO:0043025;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell body#GO:0044297;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000008441.3|UniProtKB=G3QZE1 G3QZE1 JMJD4 PTHR12480:SF6 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4 nucleic acid binding#GO:0003676;binding#GO:0005488;dioxygenase activity#GO:0051213;DNA binding#GO:0003677;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;sequence-specific DNA binding#GO:0043565;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of protein-containing complex disassembly#GO:0043244;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein metabolic process#GO:0051247;positive regulation of cellular component organization#GO:0051130;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of translation#GO:0045727 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000034950.2|UniProtKB=G3SKS3 G3SKS3 SH2D1A PTHR46051:SF10 SH2 DOMAIN-CONTAINING PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 1A regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 GORGO|Ensembl=ENSGGOG00000000856.3|UniProtKB=G3QEY6 G3QEY6 PGLYRP4 PTHR11022:SF40 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN RECOGNITION PROTEIN 4 pattern recognition receptor activity#GO:0038187;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783;signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000023716.2|UniProtKB=A0A2I2Y938 A0A2I2Y938 MRPL43 PTHR21396:SF2 39S RIBOSOMAL PROTEIN L43 LARGE RIBOSOMAL SUBUNIT PROTEIN ML43 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000024054.2|UniProtKB=G3SBD4 G3SBD4 OR10Q1 PTHR26453:SF570 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015561.3|UniProtKB=G3RHQ3 G3RHQ3 TMEM218 PTHR31622:SF1 TRANSMEMBRANE PROTEIN 218 TRANSMEMBRANE PROTEIN 218 GORGO|Ensembl=ENSGGOG00000009434.3|UniProtKB=G3R1Y2 G3R1Y2 CELA1 PTHR24257:SF35 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 1 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;response to stimulus#GO:0050896;inflammatory response#GO:0006954;metabolic process#GO:0008152;proteolysis#GO:0006508;defense response#GO:0006952;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000027574.2|UniProtKB=G3SF72 G3SF72 CSPP1 PTHR21616:SF2 CENTROSOME SPINDLE POLE ASSOCIATED PROTEIN CENTROSOME AND SPINDLE POLE-ASSOCIATED PROTEIN 1 positive regulation of cell cycle process#GO:0090068;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856 centromere DNA-binding protein#PC00071 GORGO|Gene=TAS2R40|UniProtKB=Q645Y9 Q645Y9 TAS2R40 PTHR11394:SF47 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 40 bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006673.3|UniProtKB=G3RTE2 G3RTE2 CTRC PTHR24250:SF35 CHYMOTRYPSIN-RELATED CHYMOTRYPSIN-C catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000005621.3|UniProtKB=G3QS77 G3QS77 PPP1R3A PTHR12307:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3A enzyme binding#GO:0019899;polysaccharide binding#GO:0030247;phosphatase binding#GO:0019902;binding#GO:0005488;protein phosphatase binding#GO:0019903;carbohydrate binding#GO:0030246;protein binding#GO:0005515 regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;regulation of carbohydrate biosynthetic process#GO:0043255;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000037181.1|UniProtKB=A0A2I2ZSR3 A0A2I2ZSR3 PTHR10969:SF100 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 BETA ubiquitin-like protein ligase binding#GO:0044389;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;ubiquitin protein ligase binding#GO:0031625;microtubule binding#GO:0008017;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289 response to starvation#GO:0042594;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;organelle assembly#GO:0070925;cellular response to stress#GO:0033554;cellular component disassembly#GO:0022411;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;cellular response to nutrient levels#GO:0031669;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045 autophagosome#GO:0005776;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000013151.3|UniProtKB=G3RBH7 G3RBH7 APPL2 PTHR46415:SF1 ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2 DCC-INTERACTING PROTEIN 13-BETA signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027382.2|UniProtKB=G3S5L3 G3S5L3 SLC16A6 PTHR11360:SF20 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 7 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004466.3|UniProtKB=G3QP87 G3QP87 GGN PTHR47742:SF1 GAMETOGENETIN GAMETOGENETIN ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 GORGO|Ensembl=ENSGGOG00000040734.1|UniProtKB=G3S697 G3S697 PTHR37553:SF10 DUF4705 DOMAIN-CONTAINING PROTEIN DUF4705 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000002959.3|UniProtKB=G3QKD6 G3QKD6 SV2A PTHR23511:SF11 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2A neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;export from cell#GO:0140352;signaling#GO:0023052;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;secretion by cell#GO:0032940;cellular localization#GO:0051641 transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;neuron projection#GO:0043005;presynapse#GO:0098793;cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 GORGO|Ensembl=ENSGGOG00000010619.3|UniProtKB=G3R511 G3R511 CACNA2D4 PTHR10166:SF59 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-4 calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;calcium channel complex#GO:0034704;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 transporter#PC00227;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000015884.3|UniProtKB=A0A2I2YN53 A0A2I2YN53 LDHC PTHR43128:SF5 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE C CHAIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;energy derivation by oxidation of organic compounds#GO:0015980;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000008597.3|UniProtKB=G3QZT5 G3QZT5 TRMT6 PTHR12945:SF0 TRANSLATION INITIATION FACTOR EIF3-RELATED TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000000952.3|UniProtKB=G3QF72 G3QF72 TTC36 PTHR21405:SF0 CDNA SEQUENCE BC021608 TETRATRICOPEPTIDE REPEAT PROTEIN 36 GORGO|Ensembl=ENSGGOG00000025489.2|UniProtKB=G3RTV2 G3RTV2 KCNJ9 PTHR11767:SF17 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 3 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724 GORGO|Ensembl=ENSGGOG00000010901.3|UniProtKB=G3R5P2 G3R5P2 DEFA6 PTHR11876:SF3 ALPHA-DEFENSIN 1 DEFENSIN-6 response to external stimulus#GO:0009605;defense response#GO:0006952;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to Gram-negative bacterium#GO:0050829;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000016861.3|UniProtKB=G3S251 G3S251 DCAF7 PTHR19919:SF0 WD REPEAT CONTAINING PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 7 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000016847.3|UniProtKB=G3RL05 G3RL05 PROSER3 PTHR22045:SF6 PROLINE AND SERINE-RICH PROTEIN 3 PROLINE AND SERINE-RICH PROTEIN 3 GORGO|Ensembl=ENSGGOG00000015606.3|UniProtKB=A0A2I2ZTF9 A0A2I2ZTF9 TM9SF3 PTHR10766:SF41 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3 cellular process#GO:0009987;localization within membrane#GO:0051668;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000005560.3|UniProtKB=G3QS22 G3QS22 LOC101145317 PTHR34827:SF5 INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3-RELATED INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 GORGO|Ensembl=ENSGGOG00000015133.3|UniProtKB=G3RGL3 G3RGL3 TCF15 PTHR23349:SF4 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 15 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000013672.3|UniProtKB=A0A2I2ZR54 A0A2I2ZR54 LOC101151349 PTHR23087:SF26 NONHISTONE CHROMOSOMAL PROTEIN HMG HIGH MOBILITY GROUP NUCLEOSOME BINDING DOMAIN 1 binding#GO:0005488;chromatin binding#GO:0003682 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000007173.3|UniProtKB=G3QW65 G3QW65 OSM PTHR14261:SF0 ONCOSTATIN M ONCOSTATIN-M molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 regulation of response to stress#GO:0080134;positive regulation of inflammatory response#GO:0050729;positive regulation of defense response#GO:0031349;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;positive regulation of response to external stimulus#GO:0032103;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007 cytokine#PC00083;interleukin superfamily#PC00128;intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000006760.3|UniProtKB=G3QW52 G3QW52 MYO3A PTHR46256:SF4 AGAP011099-PA MYOSIN-IIIA phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;macromolecular conformation isomerase activity#GO:0120543 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of filopodium assembly#GO:0051489;system process#GO:0003008;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of cell projection assembly#GO:0060491;positive regulation of cell projection organization#GO:0031346;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of biological quality#GO:0065008;nervous system process#GO:0050877;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;sensory perception of sound#GO:0007605;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535 intracellular membraneless organelle#GO:0043232;neuron projection#GO:0043005;membraneless organelle#GO:0043228;stereocilium#GO:0032420;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;filopodium#GO:0030175;photoreceptor inner segment#GO:0001917;intracellular organelle#GO:0043229 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000043381.1|UniProtKB=G3RUQ7 G3RUQ7 PTHR15438:SF12 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX INTERACTING PROTEIN N-TERMINAL DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000003679.3|UniProtKB=G3QM86 G3QM86 KIF9 PTHR24115:SF191 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF9 protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000001147.3|UniProtKB=G3QFQ3 G3QFQ3 WDR62 PTHR45589:SF3 WD REPEAT DOMAIN 62, ISOFORM G WD REPEAT-CONTAINING PROTEIN 62 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000004089.3|UniProtKB=G3QNA2 G3QNA2 VRK1 PTHR11909:SF78 CASEIN KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE VRK1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000044163.1|UniProtKB=G3RHS9 G3RHS9 SERP2 PTHR15601:SF20 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN 2 biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000008937.3|UniProtKB=A0A2I2Z7U9 A0A2I2Z7U9 PKN2 PTHR24356:SF322 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;PDGF signaling pathway#P00047>PKC#P01150;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 GORGO|Ensembl=ENSGGOG00000027663.2|UniProtKB=A0A2I2Z6A7 A0A2I2Z6A7 PTHR15725:SF13 ZN-FINGER, C-X8-C-X5-C-X3-H TYPE-CONTAINING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 11B-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000014564.3|UniProtKB=A0A2I2ZN10 A0A2I2ZN10 MAG PTHR12035:SF107 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN MYELIN-ASSOCIATED GLYCOPROTEIN carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000011364.3|UniProtKB=G3R6X1 G3R6X1 VARS1 PTHR11946:SF118 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047 GORGO|Ensembl=ENSGGOG00000023539.2|UniProtKB=A0A2I2Y8A2 A0A2I2Y8A2 PLAGL2 PTHR24409:SF438 ZINC FINGER PROTEIN 142 CHROMATIN MODIFICATION-RELATED PROTEIN YNG2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000008640.3|UniProtKB=G3QZY0 G3QZY0 HELZ2 PTHR43788:SF16 DNA2/NAM7 HELICASE FAMILY MEMBER 3'-5' EXORIBONUCLEASE HELZ2 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to stimulus#GO:0050896 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000038944.1|UniProtKB=A0A2I2ZUQ5 A0A2I2ZUQ5 CDC42EP2 PTHR15344:SF4 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 2 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267 positive regulation of cell projection organization#GO:0031346;regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;Rho protein signal transduction#GO:0007266;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of anatomical structure size#GO:0090066;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;intracellular signaling cassette#GO:0141124;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004772.3|UniProtKB=G3QQ24 G3QQ24 ALDH1L1 PTHR11699:SF120 ALDEHYDE DEHYDROGENASE-RELATED CYTOSOLIC 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000001011.3|UniProtKB=G3QFC8 G3QFC8 ORC5 PTHR12705:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808;nuclear origin of replication recognition complex#GO:0005664 replication origin binding protein#PC00199 GORGO|Ensembl=ENSGGOG00000025565.2|UniProtKB=G3S8K2 G3S8K2 NRARP PTHR24203:SF75 ANKYRIN REPEAT FAMILY PROTEIN NOTCH-REGULATED ANKYRIN REPEAT-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000027467.2|UniProtKB=G3S2N9 G3S2N9 LOC101124279 PTHR36465:SF1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3 cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;aerobic electron transport chain#GO:0019646;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrial respiratory chain complex assembly#GO:0033108;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;protein-containing complex organization#GO:0043933 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000026089.2|UniProtKB=A0A2I2YVY2 A0A2I2YVY2 LOC101132903 PTHR11278:SF7 40S RIBOSOMAL PROTEIN S7 40S RIBOSOMAL PROTEIN S7 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;cytosolic ribosome#GO:0022626;small-subunit processome#GO:0032040;ribosome#GO:0005840 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000027706.2|UniProtKB=G3SH45 G3SH45 CFAP96 PTHR31144:SF1 UPF0602 PROTEIN C4ORF47 CILIA-AND FLAGELLA-ASSOCIATED PROTEIN 96 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000025609.2|UniProtKB=G3RVS7 G3RVS7 PTHR23231:SF19 GERM CELL-LESS PROTEIN GERM CELL-LESS PROTEIN-LIKE 1 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000013120.3|UniProtKB=G3RBE8 G3RBE8 RPUSD3 PTHR21600:SF49 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE MITOCHONDRIAL MRNA PSEUDOURIDINE SYNTHASE RPUSD3 intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000002455.3|UniProtKB=G3QJ34 G3QJ34 MNT PTHR11969:SF99 MAX DIMERIZATION, MAD MAX-BINDING PROTEIN MNT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000012341.3|UniProtKB=G3R9F7 G3R9F7 MRPL58 PTHR11075:SF54 PEPTIDE CHAIN RELEASE FACTOR LARGE RIBOSOMAL SUBUNIT PROTEIN ML62 catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on RNA#GO:0140098;translation factor activity#GO:0180051;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 translation release factor#PC00225 GORGO|Ensembl=ENSGGOG00000002851.3|UniProtKB=G3QK36 G3QK36 PTHR45972:SF5 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 7B GORGO|Ensembl=ENSGGOG00000010547.3|UniProtKB=G3R4S6 G3R4S6 SELENBP1 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000006148.3|UniProtKB=G3QTI9 G3QTI9 DPEP1 PTHR10443:SF38 MICROSOMAL DIPEPTIDASE DIPEPTIDASE 1 catalytic activity#GO:0003824;peptidase activity#GO:0008233;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000008009.3|UniProtKB=A0A2I2YH71 A0A2I2YH71 LOC101150395 PTHR10570:SF5 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 DELTA CHAIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;immune system process#GO:0002376;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;mononuclear cell differentiation#GO:1903131;regulation of biological process#GO:0050789;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;leukocyte activation#GO:0045321;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;T cell differentiation#GO:0030217;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;side of membrane#GO:0098552 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD3 delta#P01326 GORGO|Ensembl=ENSGGOG00000007675.3|UniProtKB=G3QXG3 G3QXG3 LOC109023081 PTHR46186:SF3 CYSTATIN CYSTATIN-S-RELATED enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 vesicle#GO:0031982;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000013577.3|UniProtKB=G3RCL3 G3RCL3 PRIM1 PTHR10536:SF0 DNA PRIMASE SMALL SUBUNIT DNA PRIMASE SMALL SUBUNIT catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261 transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;replication fork#GO:0005657;nuclear DNA-directed RNA polymerase complex#GO:0055029;replisome#GO:0030894;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654 primase#PC00189 DNA replication#P00017>Primase#P00528 GORGO|Ensembl=ENSGGOG00000013608.3|UniProtKB=G3RCP3 G3RCP3 NCOA5 PTHR23295:SF3 NUCLEAR RECEPTOR COACTIVATOR 5-RELATED NUCLEAR RECEPTOR COACTIVATOR 5 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000013375.3|UniProtKB=A0A2I2Z3T7 A0A2I2Z3T7 UBE2J1 PTHR24068:SF581 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;response to stress#GO:0006950;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;ubiquitin ligase complex#GO:0000151;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000001317.3|UniProtKB=G3QG48 G3QG48 NFIL3 PTHR15284:SF1 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN rhythmic process#GO:0048511;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;circadian rhythm#GO:0007623;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000003655.3|UniProtKB=G3QM63 G3QM63 RBM15 PTHR23189:SF43 RNA RECOGNITION MOTIF-CONTAINING RNA-BINDING PROTEIN 15 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000037103.1|UniProtKB=A0A2I2YTW0 A0A2I2YTW0 PTTG2 PTHR10418:SF8 SECURIN-3 SECURIN-2 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 reproductive process#GO:0022414;cell cycle#GO:0007049;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sexual reproduction#GO:0019953;organelle organization#GO:0006996;cellular process#GO:0009987;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;meiotic chromosome segregation#GO:0045132;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000000069.3|UniProtKB=A0A2I2ZP83 A0A2I2ZP83 AK2 PTHR23359:SF227 NUCLEOTIDE KINASE ADENYLATE KINASE 2, MITOCHONDRIAL transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;ADP metabolic process#GO:0046031;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;nucleoside diphosphate metabolic process#GO:0009132 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 GORGO|Ensembl=ENSGGOG00000023979.2|UniProtKB=G3RP17 G3RP17 SMC3 PTHR43977:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 GORGO|Ensembl=ENSGGOG00000013789.3|UniProtKB=G3S7Y4 G3S7Y4 LILRA4 PTHR11738:SF98 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 4 immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;regulation of immune response#GO:0050776;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000012578.3|UniProtKB=G3RA17 G3RA17 FMO4 PTHR23023:SF74 DIMETHYLANILINE MONOOXYGENASE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 4 monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000010084.3|UniProtKB=G3R3K6 G3R3K6 LOC101140074 PTHR26450:SF424 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A4 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000023966.2|UniProtKB=G3RTX4 G3RTX4 SMAD5 PTHR13703:SF36 SMAD SMAD FAMILY MEMBER 5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to growth factor stimulus#GO:0071363;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;cellular response to transforming growth factor beta stimulus#GO:0071560;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;response to transforming growth factor beta#GO:0071559;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292;Wnt signaling pathway#P00057>Smad4#P01455 GORGO|Ensembl=ENSGGOG00000009392.3|UniProtKB=A0A2I2ZQZ6 A0A2I2ZQZ6 NOXO1 PTHR15706:SF10 SH3 MULTIPLE DOMAIN NADPH OXIDASE ORGANIZER 1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 superoxide metabolic process#GO:0006801;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000004336.3|UniProtKB=A0A2I2YS34 A0A2I2YS34 TMEM217 PTHR34928:SF2 TRANSMEMBRANE PROTEIN 217 TRANSMEMBRANE PROTEIN 217 GORGO|Ensembl=ENSGGOG00000006490.3|UniProtKB=A0A2I2ZHI8 A0A2I2ZHI8 LOC129530148 PTHR23036:SF190 CYTOKINE RECEPTOR GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR SUBUNIT ALPHA protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;cytokine receptor activity#GO:0004896 regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;negative regulation of neuron apoptotic process#GO:0043524;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;response to chemical#GO:0042221;response to cytokine#GO:0034097;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;signaling receptor complex#GO:0043235;extracellular protein-containing complex#GO:0140392 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009966.3|UniProtKB=A0A2I2Y6P7 A0A2I2Y6P7 ACSL1 PTHR43272:SF116 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 1 catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629 membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ligase#PC00142 GORGO|Ensembl=ENSGGOG00000042582.1|UniProtKB=A0A2I2Z3U9 A0A2I2Z3U9 PTHR14207:SF3 STEROL ISOMERASE EXPERA DOMAIN-CONTAINING PROTEIN intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000037102.1|UniProtKB=A0A2I2Y8T0 A0A2I2Y8T0 LOC101149382 PTHR43521:SF3 ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;nucleus#GO:0005634;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000026871.2|UniProtKB=G3SFP9 G3SFP9 CHRM4 PTHR24247:SF180 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M4 G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;acetylcholine receptor activity#GO:0015464;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960 response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;response to chemical#GO:0042221;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536 dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>mAChR2/4#P01077;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083 GORGO|Ensembl=ENSGGOG00000002624.3|UniProtKB=G3QJI8 G3QJI8 ELAC1 PTHR46018:SF2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000022979.2|UniProtKB=G3SA63 G3SA63 LOC101132981 PTHR26452:SF354 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5A1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000040753.1|UniProtKB=A0A2I2ZKL1 A0A2I2ZKL1 ZNF92 PTHR24381:SF355 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 682 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000043157.1|UniProtKB=A0A2I2ZRB0 A0A2I2ZRB0 ATG9A PTHR13038:SF13 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9A transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;reticulophagy#GO:0061709;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;localization#GO:0051179 phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000015293.3|UniProtKB=G3SJ59 G3SJ59 MGAT4C PTHR12062:SF14 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE C hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000024891.2|UniProtKB=G3RM55 G3RM55 PTHR22792:SF164 LUPUS LA PROTEIN-RELATED SUBFAMILY NOT NAMED mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000009343.3|UniProtKB=G3R1Q3 G3R1Q3 CD2AP PTHR14167:SF23 SH3 DOMAIN-CONTAINING CD2-ASSOCIATED PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027723.2|UniProtKB=G3RNG4 G3RNG4 PLXNB3 PTHR22625:SF33 PLEXIN PLEXIN-B3 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of locomotion#GO:0040012;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;system development#GO:0048731;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;negative regulation of locomotion#GO:0040013;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular component biogenesis#GO:0044085;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell differentiation#GO:0045597;negative regulation of cell migration#GO:0030336;signaling#GO:0023052;synapse assembly#GO:0007416;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008033.3|UniProtKB=G3QYC7 G3QYC7 SLC29A2 PTHR10332:SF8 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;nucleobase transport#GO:0015851;pyrimidine nucleobase transport#GO:0015855;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008153.3|UniProtKB=G3QYN2 G3QYN2 ARFIP1 PTHR12141:SF4 ARFAPTIN-RELATED ARFAPTIN-1 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;intracellular protein transport#GO:0006886;transport#GO:0006810;regulation of actin filament-based process#GO:0032970;intracellular transport#GO:0046907;regulation of actin nucleation#GO:0051125;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000001562.3|UniProtKB=G3QGS6 G3QGS6 RAB3B PTHR47980:SF22 LD44762P RAS-RELATED PROTEIN RAB-3B protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;myosin binding#GO:0017022 transport#GO:0006810;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;exocytosis#GO:0006887;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 intracellular organelle#GO:0043229;endosome#GO:0005768;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000002226.3|UniProtKB=G3SJ79 G3SJ79 HOXA11 PTHR46092:SF3 HOMEOBOX PROTEIN HOX-A11-RELATED HOMEOBOX PROTEIN HOX-A11 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;skeletal system morphogenesis#GO:0048705;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;developmental process#GO:0032502;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;skeletal system development#GO:0001501;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000012121.3|UniProtKB=A0A2I2YFM9 A0A2I2YFM9 SLC25A27 PTHR45618:SF8 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;response to cold#GO:0009409;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000043709.1|UniProtKB=G3S7A4 G3S7A4 B3GALT2 PTHR11214:SF19 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 2 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000013044.3|UniProtKB=G3RB97 G3RB97 ITGA9 PTHR23220:SF69 INTEGRIN ALPHA INTEGRIN ALPHA-9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell surface receptor signaling pathway#GO:0007166;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154 membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;integrin complex#GO:0008305 integrin#PC00126;cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin alpha#P00941 GORGO|Ensembl=ENSGGOG00000005024.3|UniProtKB=G3QQQ1 G3QQQ1 ENTPD3 PTHR11782:SF38 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110 nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434;nucleoside diphosphate metabolic process#GO:0009132;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;nucleotide phosphatase#PC00173;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000026647.2|UniProtKB=G3S280 G3S280 MCIDAS PTHR13372:SF3 GEMININ MULTICILIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of DNA replication#GO:0006275;cilium organization#GO:0044782;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;regulation of DNA-templated DNA replication initiation#GO:0030174;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;plasma membrane bounded cell projection assembly#GO:0120031 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002869.3|UniProtKB=G3QK56 G3QK56 FTCD PTHR12234:SF0 FORMIMINOTRANSFERASE-CYCLODEAMINASE FORMIMIDOYLTRANSFERASE-CYCLODEAMINASE lyase activity#GO:0016829;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000006004.3|UniProtKB=G3RNV8 G3RNV8 PPP1R14D PTHR16188:SF13 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14D protein serine/threonine phosphatase inhibitor activity#GO:0004865;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208 phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000015290.3|UniProtKB=G3S2D7 G3S2D7 UTRN PTHR12268:SF26 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 UTROPHIN cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;neuromuscular junction development#GO:0007528;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cell junction#GO:0030054;neuromuscular junction#GO:0031594;membrane protein complex#GO:0098796;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000008063.3|UniProtKB=G3S345 G3S345 PTHR14096:SF39 APOLIPOPROTEIN L APOLIPOPROTEIN L4 binding#GO:0005488;lipid binding#GO:0008289 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;apolipoprotein#PC00052 GORGO|Ensembl=ENSGGOG00000043557.1|UniProtKB=A0A2I2Z9V7 A0A2I2Z9V7 ZNF706 PTHR21213:SF34 GEO09665P1-RELATED TRANSCRIPTIONAL REGULATOR ZNF706 GORGO|Ensembl=ENSGGOG00000004582.3|UniProtKB=A0A2I2YWD2 A0A2I2YWD2 RBPJ PTHR10665:SF3 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;Notch signaling pathway#GO:0007219;cell communication#GO:0007154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Notch signaling pathway#P00045>Su(H)#P01101;Angiogenesis#P00005>CSL#P00233 GORGO|Ensembl=ENSGGOG00000010298.3|UniProtKB=G3R456 G3R456 NTAQ1 PTHR13035:SF0 PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000000192.3|UniProtKB=G3SEH0 G3SEH0 CIC PTHR13059:SF13 HMG-BOX TRANSCRIPTION FACTOR BBX PROTEIN CAPICUA HOMOLOG sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000014606.3|UniProtKB=G3RF90 G3RF90 SH2D5 PTHR15832:SF3 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG SH2 DOMAIN-CONTAINING PROTEIN 5 postsynapse#GO:0098794;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;postsynaptic density#GO:0014069;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000009000.3|UniProtKB=G3R0W2 G3R0W2 TOP1 PTHR10290:SF5 DNA TOPOISOMERASE I DNA TOPOISOMERASE 1 catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543 cell cycle#GO:0007049;organelle organization#GO:0006996;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;DNA replication#GO:0006260;cellular process#GO:0009987;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA topoisomerase#PC00017 DNA replication#P00017>DNA Topisomerase#P00536;DNA replication#P00017>Top#P00530 GORGO|Ensembl=ENSGGOG00000008947.3|UniProtKB=G3R0Q2 G3R0Q2 GDPD3 PTHR42758:SF3 PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C LYSOPHOSPHOLIPASE D GDPD3 carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;lipid metabolic process#GO:0006629;glycerophospholipid catabolic process#GO:0046475;organophosphate catabolic process#GO:0046434 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 lipase#PC00143;phospholipase#PC00186;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000003683.3|UniProtKB=G3QM87 G3QM87 PCBP3 PTHR10288:SF98 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000001109.3|UniProtKB=A0A2I2YXT1 A0A2I2YXT1 PTHR13037:SF11 FORMIN FORMIN-1 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000014142.3|UniProtKB=A0A2I2ZVE0 A0A2I2ZVE0 C20H19orf12 PTHR31493:SF1 NAZO FAMILY MEMBER PROTEIN C19ORF12 homeostatic process#GO:0042592;mitochondrial calcium ion homeostasis#GO:0051560;catabolic process#GO:0009056;intracellular monoatomic ion homeostasis#GO:0006873;process utilizing autophagic mechanism#GO:0061919;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;cellular process#GO:0009987;autophagy#GO:0006914;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000010269.3|UniProtKB=G3R432 G3R432 AGGF1 PTHR23106:SF24 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;tube development#GO:0035295 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000025520.2|UniProtKB=G3SAU0 G3SAU0 SYNPO2L PTHR24217:SF10 PUTATIVE-RELATED SYNAPTOPODIN 2-LIKE PROTEIN actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515 cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;striated muscle cell development#GO:0055002;positive regulation of organelle organization#GO:0010638;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of Rho protein signal transduction#GO:0035023;actomyosin structure organization#GO:0031032;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;positive regulation of actin filament bundle assembly#GO:0032233;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;regulation of supramolecular fiber organization#GO:1902903;myofibril assembly#GO:0030239;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;I band#GO:0031674;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000013763.3|UniProtKB=G3QSL2 G3QSL2 VAMP2 PTHR45701:SF5 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 2 protein binding#GO:0005515;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;binding#GO:0005488 protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;localization#GO:0051179;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;transport#GO:0006810;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 membrane traffic protein#PC00150 5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Circadian clock system#P00015>per#G01499;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Synaptic vesicle trafficking#P05734>Synaptobrevin#P05779;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Circadian clock system#P00015>Per#P00504;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Circadian clock system#P00015>per#G01503 GORGO|Ensembl=ENSGGOG00000013728.3|UniProtKB=G3S4J8 G3S4J8 SOAT1 PTHR10408:SF6 STEROL O-ACYLTRANSFERASE STEROL O-ACYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;heterocyclic compound binding#GO:1901363;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;alcohol binding#GO:0043178;steroid binding#GO:0005496;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;sterol binding#GO:0032934;acyltransferase activity#GO:0016746;cholesterol binding#GO:0015485;lipid binding#GO:0008289 primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;cholesterol efflux#GO:0033344;cellular process#GO:0009987;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;steroid metabolic process#GO:0008202;lipid transport#GO:0006869;transport#GO:0006810;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sterol metabolic process#GO:0016125;sterol transport#GO:0015918;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 acyltransferase#PC00042;transferase#PC00220 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 GORGO|Ensembl=ENSGGOG00000009433.3|UniProtKB=A0A2I2Z397 A0A2I2Z397 DTHD1 PTHR28336:SF4 BA1-643 DEATH DOMAIN-CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000009023.3|UniProtKB=G3R0X5 G3R0X5 WDR49 PTHR44324:SF1 WD40 REPEAT DOMAIN 95 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 337 GORGO|Ensembl=ENSGGOG00000038922.1|UniProtKB=A0A2I2YM89 A0A2I2YM89 LOC109029187 PTHR10026:SF70 CYCLIN CYCLIN-Q cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 kinase activator#PC00138;kinase modulator#PC00140 GORGO|Gene=NDUFS1|UniProtKB=Q0MQG1 Q0MQG1 NDUFS1 PTHR11615:SF377 NITRATE, FORMATE, IRON DEHYDROGENASE NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex I#GO:0045271;organelle membrane#GO:0031090;transporter complex#GO:1990351 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000026228.2|UniProtKB=A0A2I2YD52 A0A2I2YD52 PTHR11071:SF441 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000037933.1|UniProtKB=A0A2I2ZR49 A0A2I2ZR49 PTHR19970:SF34 RIBOSOMAL PROTEIN L39E RIBOSOMAL PROTEIN L39 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010033.3|UniProtKB=G3R3G9 G3R3G9 TANGO6 PTHR20959:SF1 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG establishment of localization#GO:0051234;secretion#GO:0046903;protein secretion#GO:0009306;localization#GO:0051179;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;transport#GO:0006810;export from cell#GO:0140352;macromolecule localization#GO:0033036;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;establishment of protein localization#GO:0045184 GORGO|Ensembl=ENSGGOG00000000609.3|UniProtKB=A0A2I2ZM47 A0A2I2ZM47 UBXN11 PTHR23333:SF4 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 11 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000043490.1|UniProtKB=A0A2I2ZVB4 A0A2I2ZVB4 PTHR46041:SF2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;endopeptidase complex#GO:1905369;inner mitochondrial membrane protein complex#GO:0098800 protease#PC00190 GORGO|Ensembl=ENSGGOG00000042580.1|UniProtKB=G3RV95 G3RV95 LOC101129900 PTHR12035:SF113 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIGLEC FAMILY LIKE 2 carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;binding#GO:0005488;organic acid binding#GO:0043177 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000000344.3|UniProtKB=G3QDL3 G3QDL3 UCP3 PTHR45618:SF2 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL TRANSPORTER UCP3-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075 homeostatic process#GO:0042592;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839;response to cold#GO:0009409;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;response to abiotic stimulus#GO:0009628;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;adaptive thermogenesis#GO:1990845;mitochondrial transmembrane transport#GO:1990542;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;regulation of multicellular organismal process#GO:0051239;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;response to stress#GO:0006950;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;temperature homeostasis#GO:0001659 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000039133.1|UniProtKB=A0A2I2Z4L0 A0A2I2Z4L0 PTHR23267:SF518 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-29 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000016511.3|UniProtKB=G3RK50 G3RK50 PLP1 PTHR11683:SF11 MYELIN PROTEOLIPID MYELIN PROTEOLIPID PROTEIN structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;oligodendrocyte differentiation#GO:0048709;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;axon development#GO:0061564;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;gliogenesis#GO:0042063;myelination#GO:0042552;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;myelin sheath#GO:0043209;cellular anatomical structure#GO:0110165 myelin protein#PC00161 GORGO|Ensembl=ENSGGOG00000008052.3|UniProtKB=G3S4R4 G3S4R4 LYSET PTHR31925:SF1 TRANSMEMBRANE PROTEIN 251 LYSOSOMAL ENZYME TRAFFICKING FACTOR GORGO|Ensembl=ENSGGOG00000000551.3|UniProtKB=A0A2I2YP48 A0A2I2YP48 UGGT1 PTHR11226:SF3 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 1 glucosyltransferase activity#GO:0046527;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000008559.3|UniProtKB=G3QZP9 G3QZP9 NYX PTHR24366:SF154 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS NYCTALOPIN immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000006310.3|UniProtKB=G3SG62 G3SG62 LRRC59 PTHR45752:SF4 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 59 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000022430.2|UniProtKB=A0A2I2YP82 A0A2I2YP82 TBC1D32 PTHR13465:SF3 UPF0183 PROTEIN PROTEIN BROAD-MINDED cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 GORGO|Ensembl=ENSGGOG00000005515.3|UniProtKB=G3QRY3 G3QRY3 KARS1 PTHR42918:SF16 LYSYL-TRNA SYNTHETASE LYSINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723;adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;binding#GO:0005488 positive regulation of cell activation#GO:0050867;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;tRNA aminoacylation#GO:0043039;organophosphate metabolic process#GO:0019637;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;leukocyte activation#GO:0045321;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;cell activation#GO:0001775;translation#GO:0006412;regulation of multicellular organismal process#GO:0051239;gene expression#GO:0010467;myeloid leukocyte activation#GO:0002274;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;regulation of macrophage activation#GO:0043030;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;nucleobase-containing small molecule metabolic process#GO:0055086;positive regulation of leukocyte activation#GO:0002696;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;protein biosynthetic process#GO:0160307;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;regulation of leukocyte activation#GO:0002694;cell activation involved in immune response#GO:0002263;nucleotide biosynthetic process#GO:0009165;RNA metabolic process#GO:0016070;nucleotide metabolic process#GO:0009117;immune system process#GO:0002376 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000027461.2|UniProtKB=A0A2I2Y993 A0A2I2Y993 ATF2 PTHR19304:SF9 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;Gonadotropin-releasing hormone receptor pathway#P06664>ATF2#P06732;Oxidative stress response#P00046>ATF2#P01126;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;CCKR signaling map#P06959>ATF2#P07078;Ras Pathway#P04393>ATF2#P04548 GORGO|Ensembl=ENSGGOG00000024226.2|UniProtKB=G3SAN8 G3SAN8 OR13F1 PTHR26453:SF562 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13F1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004741.3|UniProtKB=G3QPY5 G3QPY5 PEX11G PTHR20990:SF1 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11C organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;peroxisome organization#GO:0007031 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579 GORGO|Ensembl=ENSGGOG00000001666.3|UniProtKB=G3QH24 G3QH24 TESMIN PTHR12446:SF22 TESMIN/TSO1-RELATED TESMIN regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000013801.3|UniProtKB=G3RD65 G3RD65 SLC9A3 PTHR10110:SF90 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 3 potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;brush border membrane#GO:0031526;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;brush border#GO:0005903;apical plasma membrane#GO:0016324;membrane#GO:0016020;cluster of actin-based cell projections#GO:0098862;cell projection membrane#GO:0031253;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000010403.3|UniProtKB=G3R4E8 G3R4E8 MRPL15 PTHR12934:SF15 50S RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011678.3|UniProtKB=G3R7P3 G3R7P3 LOC101149534 PTHR48002:SF134 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000037389.1|UniProtKB=A0A2I2YPE4 A0A2I2YPE4 PTHR11127:SF9 60S RIBOSOMAL PROTEIN L14 60S RIBOSOMAL PROTEIN L14 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000006364.3|UniProtKB=G3QU36 G3QU36 NECTIN2 PTHR47387:SF1 NECTIN-2 NECTIN-2 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of cell communication#GO:0010646;positive regulation of adaptive immune response#GO:0002821;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;positive regulation of signaling#GO:0023056;regulation of immune response#GO:0050776;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;regulation of lymphocyte mediated immunity#GO:0002706;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical junction complex#GO:0043296;cell junction#GO:0030054;anchoring junction#GO:0070161 GORGO|Ensembl=ENSGGOG00000006607.3|UniProtKB=G3S4D8 G3S4D8 KDM6A PTHR14017:SF9 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 6A catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;chromatin DNA binding#GO:0031490;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;dioxygenase activity#GO:0051213;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;histone demethylase activity#GO:0032452;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;histone modifying activity#GO:0140993 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of macromolecule metabolic process#GO:0060255;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;multicellular organismal process#GO:0032501;heart development#GO:0007507;biological regulation#GO:0065007;developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004799.3|UniProtKB=G3QQ42 G3QQ42 ARFRP1 PTHR45909:SF1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 vesicle-mediated transport#GO:0016192;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;protein localization to Golgi apparatus#GO:0034067;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;protein localization to organelle#GO:0033365;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000022144.2|UniProtKB=G3SIG0 G3SIG0 CALR3 PTHR11073:SF3 CALRETICULIN AND CALNEXIN CALRETICULIN-3 calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein folding#GO:0006457;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000023637.2|UniProtKB=A0A2I2Z2R8 A0A2I2Z2R8 PTHR24073:SF1105 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1C-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 organelle assembly#GO:0070925;cellular localization#GO:0051641;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;vacuole organization#GO:0007033;cellular component organization#GO:0016043;catabolic process#GO:0009056;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;autophagosome organization#GO:1905037;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;establishment of protein localization#GO:0045184;cellular component assembly#GO:0022607;macroautophagy#GO:0016236 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell body#GO:0044297 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000038121.1|UniProtKB=A0A2I2YQG5 A0A2I2YQG5 PTHR15960:SF3 LD44032P UBIQUITIN-ASSOCIATED PROTEIN 1-LIKE protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;catabolic process#GO:0009056 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;ESCRT I complex#GO:0000813;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982 GORGO|Ensembl=ENSGGOG00000002190.3|UniProtKB=G3QIE7 G3QIE7 FAM241B PTHR33690:SF2 DUF4605 DOMAIN-CONTAINING PROTEIN PROTEIN FAM241B organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002201.3|UniProtKB=G3QIF9 G3QIF9 PTHR12611:SF2 PUR-TRANSCRIPTIONAL ACTIVATOR TRANSCRIPTIONAL ACTIVATOR PROTEIN PUR-ALPHA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013818.3|UniProtKB=G3RD80 G3RD80 LRRN4 PTHR24366:SF13 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT NEURONAL PROTEIN 4 multicellular organismal process#GO:0032501;system process#GO:0003008;cognition#GO:0050890;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000002128.3|UniProtKB=G3QI91 G3QI91 APEX1 PTHR22748:SF6 AP ENDONUCLEASE DNA REPAIR NUCLEASE_REDOX REGULATOR APEX1 DNA exonuclease activity#GO:0004529;3'-5' exonuclease activity#GO:0008408;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;phosphoric ester hydrolase activity#GO:0042578;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 GORGO|Ensembl=ENSGGOG00000025507.2|UniProtKB=G3SHE2 G3SHE2 ASIC5 PTHR11690:SF286 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED BILE ACID-SENSITIVE ION CHANNEL monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000026344.2|UniProtKB=G3SK94 G3SK94 CASP6 PTHR10454:SF206 CASPASE CASPASE-6 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 positive regulation of apoptotic process#GO:0043065;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;regulation of neuron apoptotic process#GO:0043523;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Caspase6#P00596;Huntington disease#P00029>Caspase 6#P00809;FAS signaling pathway#P00020>Pro-Caspase6#P00607 GORGO|Ensembl=ENSGGOG00000008382.3|UniProtKB=A0A2I2YLN5 A0A2I2YLN5 PTHR45875:SF2 METHYLTRANSFERASE N6AMT1 METHYLTRANSFERASE HEMK2 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 methyltransferase#PC00155 GORGO|Ensembl=ENSGGOG00000001677.3|UniProtKB=G3QH38 G3QH38 NEURL4 PTHR12429:SF14 NEURALIZED NEURALIZED-LIKE PROTEIN 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Notch signaling pathway#P00045>Neuralized#P01117 GORGO|Ensembl=ENSGGOG00000005255.3|UniProtKB=G3QRA2 G3QRA2 GPR101 PTHR24248:SF176 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 101-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000013741.2|UniProtKB=G3RD06 G3RD06 EID2B PTHR15556:SF4 EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2-RELATED EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2B transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000004589.3|UniProtKB=G3QPK1 G3QPK1 PTHR45752:SF21 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 63 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006588.3|UniProtKB=G3QUN9 G3QUN9 PTHR23033:SF13 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000027554.2|UniProtKB=A0A2I2ZBI1 A0A2I2ZBI1 FUBP1 PTHR10288:SF99 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000022082.2|UniProtKB=G3RNL2 G3RNL2 PTHR24248:SF141 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083 GORGO|Ensembl=ENSGGOG00000043510.1|UniProtKB=A0A2I2YH50 A0A2I2YH50 SERTAD2 PTHR16277:SF10 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 SERTA DOMAIN-CONTAINING PROTEIN 2 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000014372.3|UniProtKB=G3REM7 G3REM7 NKX2-6 PTHR24340:SF72 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000007068.3|UniProtKB=G3QVX6 G3QVX6 RND1 PTHR24072:SF23 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHO6 carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043 cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 GORGO|Ensembl=ENSGGOG00000016741.3|UniProtKB=G3RKQ3 G3RKQ3 TLCD1 PTHR13439:SF5 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 1 membrane assembly#GO:0071709;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;homeostatic process#GO:0042592;membrane organization#GO:0061024;biological regulation#GO:0065007;cellular component assembly#GO:0022607;chemical homeostasis#GO:0048878;regulation of membrane lipid distribution#GO:0097035;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000042481.1|UniProtKB=A0A2I2ZG63 A0A2I2ZG63 PTHR11661:SF11 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11 N-TERMINAL DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;binding#GO:0005488 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000034828.2|UniProtKB=G3SKD4 G3SKD4 LOC101131162 PTHR26450:SF123 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52H1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004195.3|UniProtKB=A0A2I2Z8K6 A0A2I2Z8K6 AOAH PTHR15010:SF0 ACYLOXYACYL HYDROLASE ACYLOXYACYL HYDROLASE carboxylic ester hydrolase activity#GO:0052689;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of response to stimulus#GO:0048583;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;lipopolysaccharide metabolic process#GO:0008653;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000008587.3|UniProtKB=A0A2I2ZLW3 A0A2I2ZLW3 LRRTM4 PTHR24366:SF120 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 4-RELATED immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000000213.3|UniProtKB=A0A2I2ZLM1 A0A2I2ZLM1 CHRNE PTHR18945:SF59 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT EPSILON neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;response to chemical#GO:0042221;synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;nervous system process#GO:0050877;response to stimulus#GO:0050896;signaling#GO:0023052;skeletal muscle contraction#GO:0003009;muscle system process#GO:0003012;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;system process#GO:0003008;muscle contraction#GO:0006936;transport#GO:0006810;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;neuromuscular process#GO:0050905;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;membrane depolarization#GO:0051899;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716 transporter complex#GO:1990351;cell junction#GO:0030054;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 GORGO|Ensembl=ENSGGOG00000012530.3|UniProtKB=G3R9X2 G3R9X2 RFXANK PTHR24124:SF4 ANKYRIN REPEAT FAMILY A DNA-BINDING PROTEIN RFXANK positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000043245.1|UniProtKB=A0A2I2ZHB6 A0A2I2ZHB6 PTHR23107:SF2 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN PROTEIN SSXT transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000011078.3|UniProtKB=G3R666 G3R666 TACC1 PTHR13924:SF12 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 1 nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515 organelle localization#GO:0051640;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;system development#GO:0048731;cellular localization#GO:0051641;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cell cycle process#GO:0022402;nuclear migration#GO:0007097;cellular component organization#GO:0016043;cell cycle#GO:0007049;cytoplasmic microtubule organization#GO:0031122;establishment of organelle localization#GO:0051656;cell differentiation#GO:0030154;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501 microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000005650.3|UniProtKB=G3QSA4 G3QSA4 DUXA PTHR46123:SF15 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000011323.3|UniProtKB=A0A2I2ZXP3 A0A2I2ZXP3 ATAT1 PTHR12327:SF0 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 GORGO|Ensembl=ENSGGOG00000022889.2|UniProtKB=A0A2I2YWM3 A0A2I2YWM3 PTHR12174:SF78 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2A catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;Golgi-associated vesicle membrane#GO:0030660;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;side of membrane#GO:0098552;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783;cytoplasmic side of membrane#GO:0098562;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;endomembrane system#GO:0012505;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774 protein modifying enzyme#PC00260;aspartic protease#PC00053 GORGO|Ensembl=ENSGGOG00000008512.3|UniProtKB=G3S235 G3S235 EPB41L2 PTHR23280:SF17 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 2 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 Dopamine receptor mediated signaling pathway#P05912>EPB41L2#P05952;Nicotine pharmacodynamics pathway#P06587>EPB41L2#P06598;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 GORGO|Ensembl=ENSGGOG00000013284.4|UniProtKB=G3RBU4 G3RBU4 TAOK3 PTHR47167:SF10 SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN SERINE_THREONINE-PROTEIN KINASE TAO3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cellular response to stress#GO:0080135;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of cell communication#GO:0010646;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;positive regulation of signal transduction#GO:0009967 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000000717.3|UniProtKB=G3QEK9 G3QEK9 GASK1A PTHR15905:SF5 GOLGI-ASSOCIATED KINASE 1B-RELATED GOLGI-ASSOCIATED KINASE 1A intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000005047.3|UniProtKB=G3RYL0 G3RYL0 UBXN1 PTHR46340:SF1 UBX DOMAIN-CONTAINING PROTEIN 1 UBX DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of post-translational protein modification#GO:1901873;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;negative regulation of protein ubiquitination#GO:0031397;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein modification process#GO:0031399;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of catabolic process#GO:0009894;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of cellular process#GO:0048523;regulation of protein ubiquitination#GO:0031396 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000712.3|UniProtKB=G3QEK5 G3QEK5 SCYL1 PTHR12984:SF3 SCY1-RELATED S/T PROTEIN KINASE-LIKE N-TERMINAL KINASE-LIKE PROTEIN non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000024307.2|UniProtKB=A0A2I2YWN8 A0A2I2YWN8 PTHR13999:SF4 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 3 cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;response to virus#GO:0009615;immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;response to peptide#GO:1901652;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to type II interferon#GO:0034341;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000026898.2|UniProtKB=G3RRJ0 G3RRJ0 TNFSF4 PTHR17534:SF4 OX40 LIGAND TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 4 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;tumor necrosis factor receptor superfamily binding#GO:0032813;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 positive regulation of gene expression#GO:0010628;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of leukocyte proliferation#GO:0070665;regulation of leukocyte cell-cell adhesion#GO:1903037;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biosynthetic process#GO:0009891;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;inflammatory response#GO:0006954;positive regulation of lymphocyte proliferation#GO:0050671;regulation of macromolecule metabolic process#GO:0060255;regulation of T cell proliferation#GO:0042129;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;positive regulation of cell adhesion#GO:0045785;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;positive regulation of biological process#GO:0048518;positive regulation of cell-cell adhesion#GO:0022409;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of T cell proliferation#GO:0042102;regulation of lymphocyte activation#GO:0051249;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000007147.3|UniProtKB=A0A2I2Z607 A0A2I2Z607 KIFC3 PTHR47972:SF5 KINESIN-LIKE PROTEIN KLP-3 KINESIN-LIKE PROTEIN KIFC3 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156 GORGO|Ensembl=ENSGGOG00000038835.1|UniProtKB=A0A2I2ZRX5 A0A2I2ZRX5 PTHR23036:SF179 CYTOKINE RECEPTOR INTERLEUKIN-3 RECEPTOR SUBUNIT ALPHA molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000002872.3|UniProtKB=G3QK61 G3QK61 CTC1 PTHR14865:SF2 CST COMPLEX SUBUNIT CTC1 CST COMPLEX SUBUNIT CTC1 single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;DNA binding#GO:0003677 telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;telomere maintenance via telomere lengthening#GO:0010833;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;positive regulation of DNA replication#GO:0045740;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;telomere organization#GO:0032200;regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;positive regulation of DNA metabolic process#GO:0051054 protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nuclear telomere cap complex#GO:0000783;chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000028307.2|UniProtKB=G3RZH6 G3RZH6 PTHR17085:SF6 NUCLEAR RECEPTOR COACTIVATOR 4 NUCLEAR RECEPTOR COACTIVATOR 4 N-TERMINAL DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;response to chemical#GO:0042221;response to hormone#GO:0009725;response to endogenous stimulus#GO:0009719 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000005259.3|UniProtKB=G3QRA3 G3QRA3 FPR1 PTHR24225:SF15 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;regulation of biological quality#GO:0065008;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;immune response-activating signaling pathway#GO:0002757 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000015375.3|UniProtKB=G3RH84 G3RH84 LY96 PTHR15218:SF0 MD-1, MD-2 - RELATED LYMPHOCYTE ANTIGEN 96 molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;response to lipopolysaccharide#GO:0032496;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;innate immune response-activating signaling pathway#GO:0002758;positive regulation of signal transduction#GO:0009967;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;response to other organism#GO:0051707;immune response-regulating cell surface receptor signaling pathway#GO:0002768;toll-like receptor 4 signaling pathway#GO:0034142;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;detection of stimulus#GO:0051606;activation of innate immune response#GO:0002218;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane protein complex#GO:0098796;signaling receptor complex#GO:0043235 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>MD-2#P01347 GORGO|Ensembl=ENSGGOG00000014178.3|UniProtKB=A0A2I2Z394 A0A2I2Z394 SLF1 PTHR46677:SF1 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1 protein localization to organelle#GO:0033365;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000004251.3|UniProtKB=G3QNP9 G3QNP9 ZNF497 PTHR23226:SF348 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 497 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007834.3|UniProtKB=A0A2I2ZPK5 A0A2I2ZPK5 CALML4 PTHR23048:SF45 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN-LIKE PROTEIN 4 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000009269.3|UniProtKB=G3R1I1 G3R1I1 PTHR11829:SF68 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN C1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000012876.3|UniProtKB=G3RAT3 G3RAT3 HPGDS PTHR11571:SF224 GLUTATHIONE S-TRANSFERASE HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000009584.3|UniProtKB=G3R2B2 G3R2B2 PTHR33888:SF1 RIKEN CDNA 4932415D10 GENE SPERMATOGENESIS-ASSOCIATED PROTEIN 31H1 GORGO|Ensembl=ENSGGOG00000009776.3|UniProtKB=A0A2I2YWJ0 A0A2I2YWJ0 KLHL33 PTHR45632:SF14 LD33804P KELCH-LIKE PROTEIN 33 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001987.3|UniProtKB=G3QHW8 G3QHW8 DDIT3 PTHR16833:SF0 DNA DAMAGE-INDUCIBLE TRANSCRIPT 3 DDIT3 DNA DAMAGE-INDUCIBLE TRANSCRIPT 3 PROTEIN transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to endoplasmic reticulum stress#GO:0034976;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;cellular response to biotic stimulus#GO:0071216;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;cellular response to stress#GO:0033554;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;intrinsic apoptotic signaling pathway#GO:0097193;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 Oxidative stress response#P00046>CHOP#P01130 GORGO|Ensembl=ENSGGOG00000014138.3|UniProtKB=G3RE31 G3RE31 ZC3H7B PTHR14928:SF6 MICRO-RNA BINDING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7B nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004333.3|UniProtKB=G3QNX4 G3QNX4 GALE PTHR43725:SF58 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 epimerase/racemase#PC00096 Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 GORGO|Ensembl=ENSGGOG00000002043.3|UniProtKB=G3QI17 G3QI17 LOC101139594 PTHR11736:SF83 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN TROPHININ negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000024291.2|UniProtKB=G3SJ05 G3SJ05 DNAJC22 PTHR44733:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000034864.2|UniProtKB=G3SKP9 G3SKP9 C1orf167 PTHR38493:SF1 CHROMOSOME 1 OPEN READING FRAME 167 SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000012700.3|UniProtKB=G3RAC0 G3RAC0 ARSJ PTHR10342:SF69 ARYLSULFATASE ARYLSULFATASE J hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 GORGO|Ensembl=ENSGGOG00000036651.1|UniProtKB=A0A2I2YID9 A0A2I2YID9 PTHR31879:SF7 DET1- AND DDB1-ASSOCIATED PROTEIN 1 DET1- AND DDB1-ASSOCIATED PROTEIN 1 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000004865.3|UniProtKB=A0A2I2ZSJ6 A0A2I2ZSJ6 ANO6 PTHR12308:SF21 ANOCTAMIN ANOCTAMIN-6 phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;lipid carrier activity#GO:0005319;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;intramembrane lipid carrier activity#GO:0140303;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;molecular carrier activity#GO:0140104;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 transmembrane transport#GO:0055085;plasma membrane organization#GO:0007009;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;inorganic anion transport#GO:0015698;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;cellular component organization#GO:0016043;monoatomic anion transport#GO:0006820;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;lipid transport#GO:0006869;monoatomic ion transmembrane transport#GO:0034220;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000005480.3|UniProtKB=A0A2I2Z546 A0A2I2Z546 PTHR15114:SF1 REPLICATION PROTEIN A3 REPLICATION PROTEIN A 14 KDA SUBUNIT single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular process#GO:0009987;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle lumen#GO:0043233;replisome#GO:0030894;replication fork#GO:0005657;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Cell cycle#P00013>Pre-replication Complex#P00478 GORGO|Ensembl=ENSGGOG00000008000.3|UniProtKB=G3QY97 G3QY97 KIF3A PTHR47968:SF63 CENTROMERE PROTEIN E KINESIN-LIKE PROTEIN GORGO|Ensembl=ENSGGOG00000040811.1|UniProtKB=A0A2I2YN65 A0A2I2YN65 ARF3 PTHR11711:SF422 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 3 ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 GORGO|Ensembl=ENSGGOG00000001432.3|UniProtKB=Q0MQB6 Q0MQB6 NDUFA10 PTHR10513:SF15 DEOXYNUCLEOSIDE KINASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;deoxynucleoside kinase activity#GO:0019136 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775 membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000040328.1|UniProtKB=A0A2I2YIL8 A0A2I2YIL8 PTHR11839:SF23 UDP/ADP-SUGAR PYROPHOSPHATASE ADP-SUGAR PYROPHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;pyrophosphatase#PC00196 GORGO|Ensembl=ENSGGOG00000025019.2|UniProtKB=G3RVH5 G3RVH5 ADAMTS19 PTHR13723:SF197 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 19 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000012928.3|UniProtKB=G3RAX4 G3RAX4 NPY2R PTHR24241:SF178 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 2 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000005566.3|UniProtKB=A0A2I2ZDY7 A0A2I2ZDY7 JUNB PTHR11462:SF37 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JUNB sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to lipid#GO:0033993;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;response to steroid hormone#GO:0048545;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>JUN#P06757;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838 GORGO|Ensembl=ENSGGOG00000025229.2|UniProtKB=G3RMI8 G3RMI8 CEP97 PTHR45973:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED CENTROSOMAL PROTEIN OF 97 KDA regulation of cell projection organization#GO:0031344;regulation of cilium assembly#GO:1902017;negative regulation of cellular process#GO:0048523;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;regulation of cell projection assembly#GO:0060491;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 GORGO|Ensembl=ENSGGOG00000024155.2|UniProtKB=A0A2I2ZWP5 A0A2I2ZWP5 PTHR23239:SF349 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 18 cellular process#GO:0009987;cellular component organization#GO:0016043;intermediate filament-based process#GO:0045103;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000023552.2|UniProtKB=A0A2I2YFX6 A0A2I2YFX6 TMEM64 PTHR46593:SF1 TRANSMEMBRANE PROTEIN 64 TRANSMEMBRANE PROTEIN 64 regulation of bone resorption#GO:0045124;inorganic ion homeostasis#GO:0098771;regulation of myeloid cell differentiation#GO:0045637;calcium ion homeostasis#GO:0055074;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;intracellular monoatomic ion homeostasis#GO:0006873;intracellular calcium ion homeostasis#GO:0006874;positive regulation of cell differentiation#GO:0045597;chemical homeostasis#GO:0048878;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;monoatomic ion homeostasis#GO:0050801;positive regulation of immune system process#GO:0002684;regulation of tissue remodeling#GO:0034103;regulation of hemopoiesis#GO:1903706;homeostatic process#GO:0042592;regulation of developmental process#GO:0050793;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;positive regulation of developmental process#GO:0051094;monoatomic cation homeostasis#GO:0055080;regulation of cell differentiation#GO:0045595;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of myeloid cell differentiation#GO:0045639;regulation of cell development#GO:0060284;regulation of bone remodeling#GO:0046850 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000027117.2|UniProtKB=G3RXF1 G3RXF1 TCHH PTHR34855:SF1 TRICHOHYALIN TRICHOHYALIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435 GORGO|Ensembl=ENSGGOG00000011172.3|UniProtKB=G3R6E8 G3R6E8 LOC115934282 PTHR24264:SF43 TRYPSIN-RELATED HEPATOCYTE GROWTH FACTOR ACTIVATOR SERINE PROTEASE serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;wound healing#GO:0042060;regulation of biological quality#GO:0065008;proteolysis#GO:0006508;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;hemostasis#GO:0007599;primary metabolic process#GO:0044238;zymogen activation#GO:0031638;macromolecule metabolic process#GO:0043170;blood coagulation#GO:0007596;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to stress#GO:0006950;response to wounding#GO:0009611;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;coagulation#GO:0050817 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000012683.3|UniProtKB=A0A2I2ZK05 A0A2I2ZK05 GPR161 PTHR22752:SF10 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 161 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000008660.3|UniProtKB=A0A2I2ZY04 A0A2I2ZY04 CACNA1A PTHR45628:SF3 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT P_Q-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1A gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;calcium ion transmembrane transport#GO:0070588;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;signaling#GO:0023052;import across plasma membrane#GO:0098739;anterograde trans-synaptic signaling#GO:0098916 transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;cell body#GO:0044297;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991 voltage-gated ion channel#PC00241 Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;GABA-B receptor II signaling#P05731>Ca channel#P05753;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051 GORGO|Ensembl=ENSGGOG00000004574.3|UniProtKB=G3QPJ4 G3QPJ4 PSD4 PTHR10663:SF338 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 4 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252;ruffle#GO:0001726;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000016904.3|UniProtKB=G3RL57 G3RL57 S100A13 PTHR11639:SF57 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A13 protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;perinuclear region of cytoplasm#GO:0048471;extracellular region#GO:0005576 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000006488.3|UniProtKB=A0A2I2Y8V4 A0A2I2Y8V4 PTHR16523:SF7 PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000006688.3|UniProtKB=G3QUY3 G3QUY3 C18H16orf46 PTHR36869:SF1 CHROMOSOME 16 OPEN READING FRAME 46 CHROMOSOME 16 OPEN READING FRAME 46 GORGO|Ensembl=ENSGGOG00000038030.1|UniProtKB=A0A2I2Y3E7 A0A2I2Y3E7 SMIM15 PTHR28644:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 15 SMALL INTEGRAL MEMBRANE PROTEIN 15 GORGO|Ensembl=ENSGGOG00000012529.3|UniProtKB=G3R9Y7 G3R9Y7 MYRF PTHR13029:SF16 FAMILY NOT NAMED MYELIN REGULATORY FACTOR DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;biosynthetic process#GO:0009058;membrane organization#GO:0061024;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;glial cell differentiation#GO:0010001;oligodendrocyte differentiation#GO:0048709;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;cell development#GO:0048468;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;plasma membrane organization#GO:0007009;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;nervous system development#GO:0007399;endomembrane system organization#GO:0010256;protein maturation#GO:0051604;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;myelination#GO:0042552;gliogenesis#GO:0042063;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;nucleus#GO:0005634;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000006170.3|UniProtKB=G3QTK8 G3QTK8 SGMS1 PTHR21290:SF28 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 ceramide metabolic process#GO:0006672;organophosphate biosynthetic process#GO:0090407;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 GORGO|Ensembl=ENSGGOG00000006124.3|UniProtKB=G3QTH0 G3QTH0 LOC101131208 PTHR11504:SF1 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT 6A2, MITOCHONDRIAL enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex IV#GO:0045277;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000010615.3|UniProtKB=G3R4Z2 G3R4Z2 PDGFRA PTHR24416:SF52 TYROSINE-PROTEIN KINASE RECEPTOR PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 cell motility#GO:0048870;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;multicellular organismal process#GO:0032501;cell migration#GO:0016477;biological regulation#GO:0065007;skeletal system morphogenesis#GO:0048705;positive regulation of cellular process#GO:0048522;developmental process#GO:0032502;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;skeletal system development#GO:0001501;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development#GO:0009790;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>PDGFR#P00230;PDGF signaling pathway#P00047>PDGF receptor A#P01158 GORGO|Ensembl=ENSGGOG00000012209.3|UniProtKB=G3R939 G3R939 SCFD2 PTHR11679:SF71 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 2 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000025255.2|UniProtKB=A0A2I2ZU96 A0A2I2ZU96 PTHR48068:SF1 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TAF9 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824 intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;peptidase complex#GO:1905368;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;acetyltransferase complex#GO:1902493;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;SAGA complex#GO:0000124;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123 GORGO|Ensembl=ENSGGOG00000003746.3|UniProtKB=G3QME4 G3QME4 CLCA2 PTHR10579:SF66 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 2 chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000007164.3|UniProtKB=A0A2I2ZG00 A0A2I2ZG00 GPR176 PTHR22752:SF1 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 176 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013271.3|UniProtKB=G3RBT1 G3RBT1 MGST3 PTHR10250:SF26 MICROSOMAL GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491;glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220 GORGO|Ensembl=ENSGGOG00000010902.3|UniProtKB=G3R5Q3 G3R5Q3 MINDY3 PTHR12473:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-3 deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 GORGO|Ensembl=ENSGGOG00000027840.2|UniProtKB=G3S2V7 G3S2V7 WTIP PTHR24219:SF6 LIM DOMAIN-CONTAINING PROTEIN JUB WILMS TUMOR PROTEIN 1-INTERACTING PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of hippo signaling#GO:0035331;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of translation#GO:0017148;regulation of signaling#GO:0023051;negative regulation of metabolic process#GO:0009892;regulation of hippo signaling#GO:0035330;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;miRNA-mediated post-transcriptional gene silencing#GO:0035195;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246 organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;P-body#GO:0000932;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cell-cell junction#GO:0005911;nucleus#GO:0005634;cell junction#GO:0030054;membraneless organelle#GO:0043228;adherens junction#GO:0005912 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000003761.3|UniProtKB=A0A2I2YWQ6 A0A2I2YWQ6 DRAM1 PTHR21324:SF11 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 1 regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of catabolic process#GO:0009894 lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006743.3|UniProtKB=G3QV33 G3QV33 FOXI2 PTHR11829:SF372 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000008053.3|UniProtKB=G3RUX7 G3RUX7 TASL PTHR14889:SF3 RCG36411 TLR ADAPTER INTERACTING WITH SLC15A4 ON THE LYSOSOME GORGO|Ensembl=ENSGGOG00000006095.3|UniProtKB=G3QTF1 G3QTF1 UBA5 PTHR10953:SF9 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5 ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006819.3|UniProtKB=G3QVB5 G3QVB5 ZBTB48 PTHR24409:SF451 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 431-LIKE transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022258.2|UniProtKB=G3S8X6 G3S8X6 ORC4 PTHR12087:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 molecular adaptor activity#GO:0060090;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;protein-macromolecule adaptor activity#GO:0030674;DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 nucleobase-containing compound metabolic process#GO:0006139;DNA replication#GO:0006260;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear origin of replication recognition complex#GO:0005664;membraneless organelle#GO:0043228;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 GORGO|Ensembl=ENSGGOG00000010610.3|UniProtKB=A0A2I2Z8J0 A0A2I2Z8J0 RAB6A PTHR24073:SF1089 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6A-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 cytosolic transport#GO:0016482;protein localization to organelle#GO:0033365;intra-Golgi vesicle-mediated transport#GO:0006891;protein localization to membrane#GO:0072657;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 G-protein#PC00020;small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000006449.3|UniProtKB=G3QUA6 G3QUA6 TMEM170B PTHR22779:SF4 SD17342P TRANSMEMBRANE PROTEIN 170B regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040693.1|UniProtKB=A0A2I2Z8F4 A0A2I2Z8F4 LOC101127339 PTHR11693:SF32 ATP SYNTHASE GAMMA CHAIN ATP SYNTHASE SUBUNIT GAMMA channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874 nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP synthase#PC00002 GORGO|Ensembl=ENSGGOG00000013140.3|UniProtKB=A0A2I2Z0Y8 A0A2I2Z0Y8 RIC8A PTHR12425:SF4 SYNEMBRYN CHAPERONE RIC-8A enzyme regulator activity#GO:0030234;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000036554.1|UniProtKB=A0A2I2YDL9 A0A2I2YDL9 RGS21 PTHR10845:SF160 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 21 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000000548.3|UniProtKB=G3QE53 G3QE53 EIF3J PTHR21681:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446 eukaryotic translation initiation factor 3 complex#GO:0005852;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000001693.3|UniProtKB=G3QH47 G3QH47 MYCL PTHR45851:SF5 MYC PROTO-ONCOGENE PROTEIN L-MYC-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 GORGO|Ensembl=ENSGGOG00000024673.2|UniProtKB=G3RZ55 G3RZ55 GATA6 PTHR10071:SF23 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000005355.3|UniProtKB=G3QRK0 G3QRK0 USP7 PTHR24006:SF761 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN C-TERMINAL HYDROLASE 7 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 GORGO|Ensembl=ENSGGOG00000023759.2|UniProtKB=G3SG06 G3SG06 TRMT2B PTHR45904:SF1 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG B RNA methyltransferase#PC00033 GORGO|Ensembl=ENSGGOG00000007636.3|UniProtKB=A0A2I2ZHU2 A0A2I2ZHU2 FXN PTHR16821:SF4 FRATAXIN FRATAXIN, MITOCHONDRIAL molecular carrier activity#GO:0140104;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;iron-sulfur cluster binding#GO:0051536;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506 iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000012292.3|UniProtKB=G3R9C2 G3R9C2 PSTPIP1 PTHR23065:SF51 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000014364.3|UniProtKB=G3REM6 G3REM6 ANAPC7 PTHR12558:SF36 CELL DIVISION CYCLE 16,23,27 ANAPHASE-PROMOTING COMPLEX SUBUNIT 7 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell cycle phase transition#GO:1901987;cell division#GO:0051301;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of nuclear division#GO:0051783;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;protein modification by small protein conjugation#GO:0032446;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;metabolic process#GO:0008152;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome segregation#GO:0051983;regulation of chromosome separation#GO:1905818;positive regulation of cell cycle#GO:0045787;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000042867.1|UniProtKB=A0A2I2YR92 A0A2I2YR92 CCDC66 PTHR22736:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 66 COILED-COIL DOMAIN-CONTAINING PROTEIN 66 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 intracellular organelle#GO:0043229;cilium#GO:0005929;photoreceptor inner segment#GO:0001917;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule#GO:0005874;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 GORGO|Ensembl=ENSGGOG00000004135.3|UniProtKB=G3RNE5 G3RNE5 SVEP1 PTHR19325:SF43 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731;vasculature development#GO:0001944;anatomical structure morphogenesis#GO:0009653;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;tissue development#GO:0009888 complement component#PC00078;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000000988.3|UniProtKB=A0A2I2ZI65 A0A2I2ZI65 CARD11 PTHR14559:SF4 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000001641.3|UniProtKB=G3QH00 G3QH00 MMAB PTHR12213:SF0 CORRINOID ADENOSYLTRANSFERASE CORRINOID ADENOSYLTRANSFERASE MMAB catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 oxidoreductase#PC00176;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000006578.3|UniProtKB=G3QUN1 G3QUN1 WDR46 PTHR14085:SF3 WD-REPEAT PROTEIN BING4 WD REPEAT-CONTAINING PROTEIN 46 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274 intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000038454.1|UniProtKB=G3S9U3 G3S9U3 LOC101136363 PTHR23262:SF252 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-3 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000005180.3|UniProtKB=G3QR37 G3QR37 ANKRD10 PTHR24203:SF14 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 10 GORGO|Ensembl=ENSGGOG00000036288.1|UniProtKB=A0A2I2YIF2 A0A2I2YIF2 NXPH3 PTHR17103:SF14 NEUREXOPHILIN NEUREXOPHILIN-3 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794 GABA-ergic synapse#GO:0098982;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 GORGO|Ensembl=ENSGGOG00000000435.3|UniProtKB=G3SCT5 G3SCT5 ZDHHC20 PTHR22883:SF417 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC20 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;protein targeting#GO:0006605;developmental process#GO:0032502;protein targeting to membrane#GO:0006612;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;developmental maturation#GO:0021700 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009909.3|UniProtKB=G3RV39 G3RV39 P2RX5 PTHR10125:SF12 P2X PURINOCEPTOR P2X PURINOCEPTOR 5 passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000009996.3|UniProtKB=G3R3D3 G3R3D3 FH PTHR11444:SF1 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE FUMARATE HYDRATASE, MITOCHONDRIAL catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 lyase#PC00144 TCA cycle#P00051>Fumarase#P01271 GORGO|Ensembl=ENSGGOG00000014497.3|UniProtKB=G3REZ3 G3REZ3 AK5 PTHR23359:SF79 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 5 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550 nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside diphosphate metabolic process#GO:0009132;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 GORGO|Ensembl=ENSGGOG00000006255.3|UniProtKB=G3QTT4 G3QTT4 PTHR12173:SF3 GDNF SUBFAMILY OF TGF-BETA FAMILY NEURTURIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083 multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207;neurotrophic factor#PC00163 GORGO|Ensembl=ENSGGOG00000014821.3|UniProtKB=G3RFT1 G3RFT1 AKTIP PTHR24068:SF211 UBIQUITIN-CONJUGATING ENZYME E2 AKT-INTERACTING PROTEIN acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012785.3|UniProtKB=G3RPM2 G3RPM2 PTHR22870:SF398 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000007804.3|UniProtKB=G3QXS0 G3QXS0 LOC101123873 PTHR48112:SF39 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B1-LIKE 1 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 p53 pathway#P00059>HMG1#P04619 GORGO|Ensembl=ENSGGOG00000006283.3|UniProtKB=A0A2I2YW99 A0A2I2YW99 UGP2 PTHR43511:SF4 FAMILY NOT NAMED UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GORGO|Ensembl=ENSGGOG00000009236.3|UniProtKB=G3R1F9 G3R1F9 TRIM47 PTHR25465:SF21 B-BOX DOMAIN CONTAINING E3 UBIQUITIN-PROTEIN LIGASE TRIM47 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000015117.3|UniProtKB=G3SFY7 G3SFY7 SLC25A32 PTHR45683:SF18 MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 32 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000007290.3|UniProtKB=G3QWH6 G3QWH6 VAX2 PTHR24339:SF34 HOMEOBOX PROTEIN EMX-RELATED VENTRAL ANTERIOR HOMEOBOX 2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;head development#GO:0060322;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000043531.1|UniProtKB=G3SJT0 G3SJT0 LOC109026844 PTHR23262:SF248 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-6 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000006841.3|UniProtKB=A0A2I2Z187 A0A2I2Z187 RPTOR PTHR12848:SF22 REGULATORY-ASSOCIATED PROTEIN OF MTOR REGULATORY-ASSOCIATED PROTEIN OF MTOR molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 TOR signaling#GO:0031929;regulation of cell growth#GO:0001558;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;signal transduction#GO:0007165;response to stress#GO:0006950;positive regulation of cell growth#GO:0030307;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;TORC1 signaling#GO:0038202;cellular response to stress#GO:0033554;positive regulation of growth#GO:0045927;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;regulation of catabolic process#GO:0009894;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of growth#GO:0040008;response to starvation#GO:0042594;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000010436.3|UniProtKB=G3R4H5 G3R4H5 RITA1 PTHR34917:SF1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;regulation of response to stimulus#GO:0048583;negative regulation of Notch signaling pathway#GO:0045746;establishment of localization#GO:0051234;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;nucleocytoplasmic transport#GO:0006913;regulation of Notch signaling pathway#GO:0008593;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;negative regulation of cell communication#GO:0010648;nuclear transport#GO:0051169 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000000507.3|UniProtKB=A0A2I2Z9E6 A0A2I2Z9E6 KCNMA1 PTHR10027:SF28 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1 monoatomic cation channel activity#GO:0005261;monoatomic ion-gated channel activity#GO:0022839;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium-activated potassium channel activity#GO:0015269;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836 vasodilation#GO:0042311;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;multicellular organismal process#GO:0032501;potassium ion transport#GO:0006813;blood circulation#GO:0008015;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;transport#GO:0006810 cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000005738.3|UniProtKB=G3QSH7 G3QSH7 LOC101147054 PTHR24242:SF357 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000025144.2|UniProtKB=G3S9Y4 G3S9Y4 PTHR11224:SF42 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000010596.4|UniProtKB=G3R4X5 G3R4X5 TMCO3 PTHR16254:SF14 POTASSIUM/PROTON ANTIPORTER-RELATED SOLUTE CARRIER FAMILY 9 MEMBER D1 GORGO|Ensembl=ENSGGOG00000007951.3|UniProtKB=G3QY46 G3QY46 PIGW PTHR20661:SF0 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN GLUCOSAMINYL-PHOSPHATIDYLINOSITOL-ACYLTRANSFERASE PIGW catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000006527.3|UniProtKB=G3QUI3 G3QUI3 GCM1 PTHR12414:SF6 GLIAL CELLS MISSING RELATED/GLIDE CHORION-SPECIFIC TRANSCRIPTION FACTOR GCMA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;nervous system development#GO:0007399;embryo development#GO:0009790;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;gliogenesis#GO:0042063;placenta development#GO:0001890;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000015232.3|UniProtKB=A0A2I2YY71 A0A2I2YY71 SLC35F4 PTHR19346:SF2 SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN SOLUTE CARRIER FAMILY 35 MEMBER F4 GORGO|Ensembl=ENSGGOG00000014427.3|UniProtKB=A0A2I2Y5S7 A0A2I2Y5S7 UNC79 PTHR21696:SF2 PROTEIN UNC-79 HOMOLOG PROTEIN UNC-79 HOMOLOG GORGO|Ensembl=ENSGGOG00000003828.3|UniProtKB=A0A2I2YX62 A0A2I2YX62 CEP85L PTHR31075:SF2 CENTROSOMAL PROTEIN OF 85 KDA CENTROSOMAL PROTEIN OF 85 KDA-LIKE microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000013035.3|UniProtKB=G3RB94 G3RB94 SYCP2L PTHR15607:SF14 SYNAPTONEMAL COMPLEX PROTEIN-RELATED SYNAPTONEMAL COMPLEX PROTEIN 2-LIKE chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;membrane-enclosed lumen#GO:0031974;synaptonemal structure#GO:0099086;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000036997.1|UniProtKB=G3RYU8 G3RYU8 PTHR24384:SF127 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 257-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016253.3|UniProtKB=G3RJG5 G3RJG5 PTHR24103:SF621 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 43B ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;immune system process#GO:0002376;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000001077.3|UniProtKB=G3QFI8 G3QFI8 ARMH1 PTHR34258:SF1 ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 1 ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 1 GORGO|Ensembl=ENSGGOG00000026935.2|UniProtKB=G3SGZ3 G3SGZ3 WBP4 PTHR13173:SF10 WW DOMAIN BINDING PROTEIN 4 WW DOMAIN-BINDING PROTEIN 4 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;gene expression#GO:0010467 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000016970.3|UniProtKB=G3RLC1 G3RLC1 SIGLEC1 PTHR47243:SF1 SIALOADHESIN SIALOADHESIN protein binding#GO:0005515;binding#GO:0005488 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;biological process involved in interspecies interaction between organisms#GO:0044419;biological process involved in interaction with host#GO:0051701;biological process involved in symbiotic interaction#GO:0044403;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;late endosome#GO:0005770 GORGO|Ensembl=ENSGGOG00000040418.1|UniProtKB=A0A2I2Z7Y8 A0A2I2Z7Y8 PTHR35819:SF4 PICALM INTERACTING MITOTIC REGULATOR PIMREG PICALM INTERACTING MITOTIC REGULATOR GORGO|Ensembl=ENSGGOG00000043044.1|UniProtKB=G3RAH8 G3RAH8 SYCE1L PTHR21731:SF1 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1-LIKE SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1-LIKE intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;condensed chromosome#GO:0000793;synaptonemal structure#GO:0099086;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 GORGO|Ensembl=ENSGGOG00000014163.3|UniProtKB=G3RE39 G3RE39 ACTRT2 PTHR11937:SF38 ACTIN ACTIN-RELATED PROTEIN T2 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin and actin related protein#PC00039 GORGO|Ensembl=ENSGGOG00000016500.3|UniProtKB=G3RZ16 G3RZ16 PRCP PTHR11010:SF127 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of locomotion#GO:0040012;tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to wounding#GO:0009611;response to stress#GO:0006950;wound healing#GO:0042060;system development#GO:0048731;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;regulation of cell motility#GO:2000145;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;response to stimulus#GO:0050896;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514 lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000008173.3|UniProtKB=G3QYP9 G3QYP9 ZNF517 PTHR24381:SF455 ZINC FINGER PROTEIN RB-ASSOCIATED KRAB ZINC FINGER PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000013714.3|UniProtKB=G3RCY3 G3RCY3 KRT222 PTHR47082:SF1 KERATIN-LIKE PROTEIN KRT222 KERATIN-LIKE PROTEIN KRT222 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000023389.2|UniProtKB=G3RQP9 G3RQP9 ZFP3 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007789.3|UniProtKB=G3QXR4 G3QXR4 RAE1 PTHR10971:SF11 MRNA EXPORT FACTOR AND BUB3 MRNA EXPORT FACTOR RAE1 binding#GO:0005488;nucleic acid binding#GO:0003676;ubiquitin binding#GO:0043130;RNA binding#GO:0003723;protein binding#GO:0005515 localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;chromosome organization#GO:0051276;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;organelle organization#GO:0006996;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000002103.3|UniProtKB=A0A2I2YVN9 A0A2I2YVN9 LZTFL1 PTHR21635:SF0 LEUCINE ZIPPER TRANSCRIPTION FACTOR LIKE LEUCINE ZIPPER TRANSCRIPTION FACTOR-LIKE PROTEIN 1 regulation of biological process#GO:0050789;sperm motility#GO:0097722;negative regulation of biological process#GO:0048519;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;regulation of protein localization#GO:0032880;cilium-dependent cell motility#GO:0060285;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;biological regulation#GO:0065007;flagellated sperm motility#GO:0030317;regulation of localization#GO:0032879;microtubule-based process#GO:0007017 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000036647.1|UniProtKB=A0A2I2ZY02 A0A2I2ZY02 GPC3 PTHR10822:SF4 GLYPICAN GLYPICAN-3 regulation of signaling#GO:0023051;regulation of protein localization#GO:0032880;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of localization#GO:0032879;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;cell migration#GO:0016477 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000036809.1|UniProtKB=A0A2I2ZHK1 A0A2I2ZHK1 GABRA5 PTHR18945:SF23 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-5 signaling receptor activity#GO:0038023;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;chloride transport#GO:0006821;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;nervous system development#GO:0007399;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;animal gross anatomical part developmental process#GO:0160108;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;signaling#GO:0023052;synapse assembly#GO:0007416 signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000006854.3|UniProtKB=G3QVE4 G3QVE4 AMDHD1 PTHR42752:SF1 IMIDAZOLONEPROPIONASE IMIDAZOLONEPROPIONASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000006195.3|UniProtKB=G3QTM7 G3QTM7 NGB PTHR46458:SF1 BLR2807 PROTEIN NEUROGLOBIN molecular carrier activity#GO:0140104;binding#GO:0005488;small molecule binding#GO:0036094 response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;response to hypoxia#GO:0001666 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000008954.3|UniProtKB=G3R0Q7 G3R0Q7 GJB5 PTHR11984:SF29 CONNEXIN GAP JUNCTION BETA-5 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 cell junction protein#PC00070;gap junction#PC00105 GORGO|Ensembl=ENSGGOG00000003476.3|UniProtKB=A0A2I2ZAN4 A0A2I2ZAN4 PTHR24381:SF265 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 266 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022865.2|UniProtKB=G3SJN6 G3SJN6 BCKDHB PTHR42980:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL transferase complex#GO:1990234;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000003082.3|UniProtKB=G3S686 G3S686 PTHR15352:SF3 LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1 INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 2 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039362.1|UniProtKB=A0A2I2Y5N8 A0A2I2Y5N8 CCDC71L PTHR14484:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 COILED-COIL DOMAIN-CONTAINING PROTEIN 71L GORGO|Ensembl=ENSGGOG00000004270.3|UniProtKB=G3QNR9 G3QNR9 PTHR23324:SF42 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 4 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000012040.3|UniProtKB=G3SHI7 G3SHI7 ZPLD1 PTHR14002:SF24 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004480.3|UniProtKB=G3QPA6 G3QPA6 KCTD9 PTHR14136:SF39 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 GORGO|Ensembl=ENSGGOG00000022121.2|UniProtKB=G3SBY8 G3SBY8 SMAD1 PTHR13703:SF23 SMAD SMAD FAMILY MEMBER 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;BMP signaling pathway#GO:0030509;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;response to transforming growth factor beta#GO:0071559 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292;Wnt signaling pathway#P00057>Smad4#P01455 GORGO|Ensembl=ENSGGOG00000010065.3|UniProtKB=G3R3J3 G3R3J3 PSMG2 PTHR12970:SF1 PROTEASOME ASSEMBLY CHAPERONE 2 PROTEASOME ASSEMBLY CHAPERONE 2 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000009393.3|UniProtKB=G3SAE2 G3SAE2 MYO9B PTHR46184:SF2 UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UNCONVENTIONAL MYOSIN-IXB anion binding#GO:0043168;small molecule binding#GO:0036094;polypeptide conformation or assembly isomerase activity#GO:0120544;ion binding#GO:0043167;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;nucleotide binding#GO:0000166;ATP binding#GO:0005524;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;cytoskeletal motor activity#GO:0003774;heterocyclic compound binding#GO:1901363 cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;developmental process#GO:0032502;actin filament-based process#GO:0030029;plasma membrane bounded cell projection morphogenesis#GO:0120039;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;actin filament-based movement#GO:0030048;cellular component organization#GO:0016043 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;ruffle#GO:0001726;cytoskeleton#GO:0005856;actin filament#GO:0005884;lamellipodium#GO:0030027;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cell leading edge#GO:0031252 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000014445.3|UniProtKB=G3REU8 G3REU8 HDAC10 PTHR10625:SF43 HISTONE DEACETYLASE HDAC1-RELATED POLYAMINE DEACETYLASE HDAC10 histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007 cytosol#GO:0005829;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000004339.3|UniProtKB=G3QNX8 G3QNX8 HMGCL PTHR42738:SF1 HYDROXYMETHYLGLUTARYL-COA LYASE HYDROXYMETHYLGLUTARYL-COA LYASE, MITOCHONDRIAL carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;lyase activity#GO:0016829 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;lipid biosynthetic process#GO:0008610;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 lyase#PC00144 GORGO|Ensembl=ENSGGOG00000011500.3|UniProtKB=G3R784 G3R784 PPP2R2A PTHR11871:SF2 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B ALPHA ISOFORM molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cytosol#GO:0005829 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 GORGO|Ensembl=ENSGGOG00000022404.2|UniProtKB=G3RQJ2 G3RQJ2 MHC-DMB PTHR19944:SF65 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DM BETA CHAIN protein-containing complex binding#GO:0044877;peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;regulation of immune response#GO:0050776;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell adhesion#GO:0045785;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;regulation of T cell activation#GO:0050863;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;late endosome membrane#GO:0031902;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 GORGO|Ensembl=ENSGGOG00000001154.3|UniProtKB=G3QFR1 G3QFR1 ASAP3 PTHR45854:SF1 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of actin filament bundle assembly#GO:0032231;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cell migration#GO:0016477;regulation of actin filament-based process#GO:0032970 anchoring junction#GO:0070161;ruffle#GO:0001726;cell junction#GO:0030054;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252 GORGO|Ensembl=ENSGGOG00000006222.3|UniProtKB=G3QTQ5 G3QTQ5 KCNC3 PTHR11537:SF184 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL KCNC3 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;action potential#GO:0001508;metal ion transport#GO:0030001;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 neuronal cell body#GO:0043025;neuron projection terminus#GO:0044306;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;membrane#GO:0016020;cell periphery#GO:0071944;axon terminus#GO:0043679;voltage-gated potassium channel complex#GO:0008076;neuron projection membrane#GO:0032589;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;postsynapse#GO:0098794;cell body#GO:0044297;cell projection membrane#GO:0031253;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;protein-containing complex#GO:0032991;cell leading edge#GO:0031252;presynapse#GO:0098793;neuron projection#GO:0043005;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;synaptic membrane#GO:0097060 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000041951.1|UniProtKB=A0A2I2ZK68 A0A2I2ZK68 SGPP2 PTHR14969:SF14 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 primary metabolic process#GO:0044238;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;small molecule metabolic process#GO:0044281;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000023271.2|UniProtKB=G3RS65 G3RS65 HMX3 PTHR24340:SF80 HOMEOBOX PROTEIN NKX H6 FAMILY HOMEOBOX 3 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000009667.3|UniProtKB=A0A2I2ZYS8 A0A2I2ZYS8 VSTM2A PTHR12207:SF23 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2A membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000010592.3|UniProtKB=G3SGQ5 G3SGQ5 PRSS37 PTHR24271:SF61 KALLIKREIN-RELATED INACTIVE SERINE PROTEASE 37-RELATED catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of reproductive process#GO:2000241;gene expression#GO:0010467;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000038734.1|UniProtKB=A0A2I2ZJN0 A0A2I2ZJN0 PTHR11931:SF31 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE (2,3-DIPHOSPHOGLYCERATE-DEPENDENT) intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868;phosphoglycerate mutase activity#GO:0004619;isomerase activity#GO:0016853 carbohydrate metabolic process#GO:0005975;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 mutase#PC00160;isomerase#PC00135 GORGO|Ensembl=ENSGGOG00000034931.2|UniProtKB=G3SKL0 G3SKL0 PTHR10019:SF18 SNF5 SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY B MEMBER 1 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000026780.2|UniProtKB=G3S1P2 G3S1P2 DCAF8L2 PTHR15574:SF42 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 8-LIKE PROTEIN 2 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000001456.3|UniProtKB=G3QGH8 G3QGH8 SLC7A14 PTHR43243:SF17 INNER MEMBRANE TRANSPORTER YGJI-RELATED SOLUTE CARRIER FAMILY 7 MEMBER 14 amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000042559.1|UniProtKB=A0A2I2ZMP6 A0A2I2ZMP6 PTHR11849:SF286 ETS TRANSCRIPTION FACTOR SPI-C transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000009087.3|UniProtKB=G3R143 G3R143 FYB2 PTHR16830:SF1 SH2 CONTAINING ADAPTOR PRAM-1 RELATED FYN-BINDING PROTEIN 2 regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;protein localization to membrane#GO:0072657;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular localization#GO:0051641;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;protein localization to cell periphery#GO:1990778;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;localization within membrane#GO:0051668;regulation of immune response#GO:0050776;cell communication#GO:0007154;localization#GO:0051179;macromolecule localization#GO:0033036;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000011057.3|UniProtKB=A0A2I2ZY55 A0A2I2ZY55 UBE2G1 PTHR24067:SF3 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G1 ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000023413.2|UniProtKB=A0A2I2Z681 A0A2I2Z681 PTHR11595:SF61 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-BETA enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 translation elongation factor#PC00222 GORGO|Ensembl=ENSGGOG00000008102.3|UniProtKB=G3QYI9 G3QYI9 GDPD4 PTHR23344:SF13 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 6 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000014315.3|UniProtKB=G3REH3 G3REH3 CPOX PTHR10755:SF0 COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;cellular process#GO:0009987;porphyrin-containing compound biosynthetic process#GO:0006779;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175;metabolite interconversion enzyme#PC00262 Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980 GORGO|Ensembl=ENSGGOG00000022042.2|UniProtKB=G3R7C9 G3R7C9 PTHR38140:SF5 KERATIN-ASSOCIATED PROTEIN 19-3-RELATED KERATIN-ASSOCIATED PROTEIN 19-4-RELATED structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000026733.2|UniProtKB=A0A2I2YGX5 A0A2I2YGX5 RAC1 PTHR24072:SF395 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 regulation of developmental process#GO:0050793;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;supramolecular fiber organization#GO:0097435;system development#GO:0048731;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cortical cytoskeleton organization#GO:0030865;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;signaling#GO:0023052;cell differentiation#GO:0030154;cell projection organization#GO:0030030;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;Rac protein signal transduction#GO:0016601;generation of neurons#GO:0048699;establishment or maintenance of cell polarity#GO:0007163;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;neuron projection guidance#GO:0097485;actin filament organization#GO:0007015;neurogenesis#GO:0022008;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;cell projection assembly#GO:0030031;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;neuron differentiation#GO:0030182 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 G-protein#PC00020;small GTPase#PC00208 CCKR signaling map#P06959>RAC1-GTP#P07214;Huntington disease#P00029>Rac#P00775;EGF receptor signaling pathway#P00018>Rac#P00564;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by semaphorins#P00007>Rac#P00340;VEGF signaling pathway#P00056>Rac#P01421;CCKR signaling map#P06959>RAC1-GDP#P07225;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Integrin signalling pathway#P00034>Rac#P00927;T cell activation#P00053>rac#P01324;Gonadotropin-releasing hormone receptor pathway#P06664>Rac1#P06860;FGF signaling pathway#P00021>Rac#P00645;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rac#P00872;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;Axon guidance mediated by netrin#P00009>Rac#P00366;p38 MAPK pathway#P05918>Rac#P06021;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;B cell activation#P00010>Rac#P00385 GORGO|Ensembl=ENSGGOG00000009195.3|UniProtKB=G3R1D1 G3R1D1 PRKAR2A PTHR11635:SF153 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY SUBUNIT anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;enzyme inhibitor activity#GO:0004857;nucleotide binding#GO:0000166;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;binding#GO:0005488;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;protein kinase A binding#GO:0051018;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;kinase inhibitor activity#GO:0019210;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Enkephalin release#P05913>PKA#P05972;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;GABA-B receptor II signaling#P05731>PKA#P05752;Endothelin signaling pathway#P00019>PKA#P00570;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Hedgehog signaling pathway#P00025>PKA#P00682;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075 GORGO|Ensembl=ENSGGOG00000026942.2|UniProtKB=G3S902 G3S902 PTHR24248:SF130 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2B ADRENERGIC RECEPTOR molecular transducer activity#GO:0060089;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;hormone binding#GO:0042562;G protein-coupled amine receptor activity#GO:0008227 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 GORGO|Ensembl=ENSGGOG00000016001.3|UniProtKB=G3RXD4 G3RXD4 USH1C PTHR23116:SF36 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED HARMONIN inner ear development#GO:0048839;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;sensory organ development#GO:0007423;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system process#GO:0003008;cellular component organization#GO:0016043;inner ear receptor cell stereocilium organization#GO:0060122;sensory perception of sound#GO:0007605;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;generation of neurons#GO:0048699;sensory perception#GO:0007600;anatomical structure development#GO:0048856;neuron development#GO:0048666;ear development#GO:0043583;system development#GO:0048731 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;cilium#GO:0005929;intracellular organelle#GO:0043229;photoreceptor inner segment#GO:0001917;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;stereocilium#GO:0032420;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000041496.1|UniProtKB=A0A2I2Z7L4 A0A2I2Z7L4 PTHR11252:SF10 POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;mitochondrial RNA processing#GO:0000963;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;RNA 3'-end processing#GO:0031123;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000008433.3|UniProtKB=G3S0G3 G3S0G3 PSAP PTHR11480:SF107 SAPOSIN-RELATED PROSAPOSIN lipid binding#GO:0008289;binding#GO:0005488;antigen binding#GO:0003823 G protein-coupled receptor signaling pathway#GO:0007186;regulation of lipid metabolic process#GO:0019216;animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;reproductive system development#GO:0061458;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;reproductive process#GO:0022414;reproductive structure development#GO:0048608;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;metabolic process#GO:0008152;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;lipid metabolic process#GO:0006629;growth#GO:0040007;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental growth#GO:0048589;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 intracellular organelle#GO:0043229;extracellular region#GO:0005576;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015231.3|UniProtKB=G3RGV5 G3RGV5 MOSPD2 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 organelle membrane contact site#GO:0044232;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000009082.3|UniProtKB=G3R129 G3R129 MMRN2 PTHR15427:SF6 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER MULTIMERIN-2 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 developmental process#GO:0032502;cell adhesion mediated by integrin#GO:0033627;negative regulation of cellular process#GO:0048523;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular process#GO:0009987;negative regulation of cell population proliferation#GO:0008285;tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;regulation of cell population proliferation#GO:0042127;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000007779.3|UniProtKB=G3QXQ8 G3QXQ8 PTHR15739:SF4 ZINC FINGER PROTEIN F-BOX ONLY PROTEIN 41 GORGO|Ensembl=ENSGGOG00000016037.3|UniProtKB=G3RIX3 G3RIX3 LOC101145835 PTHR12832:SF21 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11-LIKE X-LINKED PROTEIN 1-RELATED regulation of cell differentiation#GO:0045595;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cell development#GO:0060284;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239;regulation of reproductive process#GO:2000241;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 secretory vesicle#GO:0099503;cytoplasm#GO:0005737;endomembrane system#GO:0012505;sperm flagellum#GO:0036126;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929;acrosomal vesicle#GO:0001669;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000015647.3|UniProtKB=A0A2I2YTL4 A0A2I2YTL4 ZCRB1 PTHR46259:SF2 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000039558.1|UniProtKB=A0A2I2YJD3 A0A2I2YJD3 PTHR24377:SF622 IP01015P-RELATED ZINC FINGER PROTEIN 8 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000028153.2|UniProtKB=G3S8F8 G3S8F8 CNN2 PTHR46756:SF30 TRANSGELIN CALPONIN-2 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;intracellular protein localization#GO:0008104;actin filament organization#GO:0007015;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;protein localization to microtubule cytoskeleton#GO:0072698;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule-based process#GO:0032886;actin filament-based process#GO:0030029;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;supramolecular fiber organization#GO:0097435;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;actin filament bundle#GO:0032432;microtubule end#GO:1990752;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;stress fiber#GO:0001725;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actomyosin#GO:0042641;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000013552.3|UniProtKB=G3RCJ3 G3RCJ3 PRKCQ PTHR24356:SF181 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C THETA TYPE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Apoptosis signaling pathway#P00006>PKCs#P00318;FGF signaling pathway#P00021>PKC#P00648;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Wnt signaling pathway#P00057>Protein Kinase C#P01458;CCKR signaling map#P06959>PKCtheta#P07140;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;T cell activation#P00053>PKC-theta#P01318;Endothelin signaling pathway#P00019>PKC#P00568;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;Gonadotropin-releasing hormone receptor pathway#P06664>PKCe/theta#P06798;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 GORGO|Ensembl=ENSGGOG00000007867.3|UniProtKB=G3QXW9 G3QXW9 GLT6D1 PTHR10462:SF27 GLYCOSYLTRANSFERASE-RELATED GLYCOSYLTRANSFERASE 6 DOMAIN-CONTAINING PROTEIN 1-RELATED glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000022549.2|UniProtKB=A0A2I2Z8C4 A0A2I2Z8C4 PTHR12210:SF128 DULLARD PROTEIN PHOSPHATASE CTD NUCLEAR ENVELOPE PHOSPHATASE 1 hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000013410.3|UniProtKB=G3RC56 G3RC56 TMEM160 PTHR16236:SF0 TRANSMEMBRANE PROTEIN 160 TRANSMEMBRANE PROTEIN 160 GORGO|Ensembl=ENSGGOG00000028130.2|UniProtKB=G3S509 G3S509 PCBP1 PTHR10288:SF96 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 1 RNA binding#GO:0003723;DNA binding#GO:0003677;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697 regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000022732.2|UniProtKB=G3S1J4 G3S1J4 SST PTHR10558:SF2 SOMATOSTATIN SOMATOSTATIN hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000005324.3|UniProtKB=G3QRG2 G3QRG2 KRT9 PTHR23239:SF96 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 9 structural molecule activity#GO:0005198 supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cellular process#GO:0009987;organelle organization#GO:0006996 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000010822.3|UniProtKB=G3R5H3 G3R5H3 NHEJ1 PTHR32235:SF1 NON-HOMOLOGOUS END-JOINING FACTOR 1 NON-HOMOLOGOUS END-JOINING FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;DNA repair complex#GO:1990391;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000022437.2|UniProtKB=A0A2I2Y5T9 A0A2I2Y5T9 PTHR12391:SF7 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000002537.3|UniProtKB=G3QJB0 G3QJB0 NYAP2 PTHR22633:SF1 NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2-RELATED NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;anatomical structure development#GO:0048856;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;system development#GO:0048731;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008999.3|UniProtKB=G3R0V0 G3R0V0 MOCS3 PTHR10953:SF254 UBIQUITIN-ACTIVATING ENZYME E1 ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;protein modification by small protein conjugation or removal#GO:0070647;tRNA thio-modification#GO:0034227;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;protein modification by small protein conjugation#GO:0032446;tRNA wobble position uridine thiolation#GO:0002143;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000025015.2|UniProtKB=A0A2I2YHQ3 A0A2I2YHQ3 PTHR12921:SF0 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 reticulophagy#GO:0061709;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;autophagy#GO:0006914;catabolic process#GO:0009056;response to stimulus#GO:0050896;macroautophagy#GO:0016236;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554;process utilizing autophagic mechanism#GO:0061919 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000008185.3|UniProtKB=A0A2I2YPS9 A0A2I2YPS9 LOC101153526 PTHR23226:SF455 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 7 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010729.3|UniProtKB=A0A2I2YZT3 A0A2I2YZT3 OGDH PTHR23152:SF7 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX COMPONENT E1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 TCA cycle#P00051>alphaketoglutarate Dehydrogenase#P01269 GORGO|Ensembl=ENSGGOG00000015297.3|UniProtKB=G3S022 G3S022 SPAG9 PTHR13886:SF2 JNK/SAPK-ASSOCIATED PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4 signaling adaptor activity#GO:0035591;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;MAP kinase scaffold activity#GO:0005078;structural molecule activity#GO:0005198;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein complex scaffold activity#GO:0140378;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000042808.1|UniProtKB=A0A2I2ZTY2 A0A2I2ZTY2 LOC101132801 PTHR21107:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19 mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005 mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000004324.3|UniProtKB=A0A2I2Y584 A0A2I2Y584 LOC101130854 PTHR24223:SF241 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;tripeptide transmembrane transporter activity#GO:0042937;oligopeptide transmembrane transporter activity#GO:0035673;xenobiotic transmembrane transporter activity#GO:0042910;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;carboxylic acid transmembrane transporter activity#GO:0046943 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;oligopeptide transport#GO:0006857;xenobiotic transport#GO:0042908;transport#GO:0006810;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 GORGO|Ensembl=ENSGGOG00000022122.2|UniProtKB=G3RYS7 G3RYS7 HDGFL2 PTHR12550:SF18 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR-RELATED PROTEIN 2 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;histone H3K9me2/3 reader activity#GO:0062072;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000005546.3|UniProtKB=G3QS15 G3QS15 PNCK PTHR24347:SF440 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1B protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;calcium/calmodulin-dependent protein kinase activity#GO:0004683;catalytic activity, acting on a protein#GO:0140096;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000010924.3|UniProtKB=G3R5R6 G3R5R6 INPP5E PTHR46625:SF1 72 KDA INOSITOL POLYPHOSPHATE 5-PHOSPHATASE PHOSPHATIDYLINOSITOL POLYPHOSPHATE 5-PHOSPHATASE TYPE IV catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;membraneless organelle#GO:0043228;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;endomembrane system#GO:0012505 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000026721.2|UniProtKB=G3RSK9 G3RSK9 CISD3 PTHR46491:SF3 CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 GORGO|Ensembl=ENSGGOG00000014440.3|UniProtKB=G3RET8 G3RET8 OBI1 PTHR14609:SF1 RING FINGER PROTEIN 219 ORC UBIQUITIN LIGASE 1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787 regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of DNA replication#GO:0006275 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000001832.3|UniProtKB=G3RZI8 G3RZI8 SALL4 PTHR23233:SF19 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000007370.3|UniProtKB=G3QWP8 G3QWP8 RGP1 PTHR12507:SF3 REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED RAB6A-GEF COMPLEX PARTNER PROTEIN 2 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;membrane#GO:0016020;cytoplasm#GO:0005737;guanyl-nucleotide exchange factor complex#GO:0032045;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000011602.3|UniProtKB=G3R7I2 G3R7I2 SLC5A6 PTHR42985:SF2 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;sodium ion transport#GO:0006814;vitamin transport#GO:0051180;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monocarboxylic acid transport#GO:0015718 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000006392.3|UniProtKB=G3S5H7 G3S5H7 PAIP2 PTHR13154:SF2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 translation regulator activity#GO:0045182 negative regulation of translation#GO:0017148;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000006422.3|UniProtKB=G3QU86 G3QU86 PRP4K PTHR24058:SF103 DUAL SPECIFICITY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000026411.2|UniProtKB=G3RZ77 G3RZ77 SRR PTHR43050:SF3 SERINE / THREONINE RACEMASE FAMILY MEMBER SERINE RACEMASE catalytic activity#GO:0003824;isomerase activity#GO:0016853;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;racemase and epimerase activity#GO:0016854;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;metal ion binding#GO:0046872;lyase activity#GO:0016829 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000024606.2|UniProtKB=G3SCP5 G3SCP5 LOC101149677 PTHR15140:SF69 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE COFACTOR E-LIKE PROTEIN binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000039445.1|UniProtKB=A0A2I2YRJ3 A0A2I2YRJ3 PTHR10052:SF50 60S RIBOSOMAL PROTEIN L18A LARGE RIBOSOMAL SUBUNIT PROTEIN EL20 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000037885.1|UniProtKB=A0A2I2ZLR7 A0A2I2ZLR7 PTHR46232:SF2 SMARCE1 REGULATOR OF CHROMATIN SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1 DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 GORGO|Ensembl=ENSGGOG00000014095.3|UniProtKB=A0A2I2Y7G1 A0A2I2Y7G1 PACRG PTHR21207:SF7 PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED PARKIN COREGULATED GENE PROTEIN Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 cytosol#GO:0005829;vesicle#GO:0031982;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000007942.3|UniProtKB=G3QY39 G3QY39 FTHL17 PTHR11431:SF97 FERRITIN FERRITIN HEAVY POLYPEPTIDE-LIKE 17-RELATED ferrous iron binding#GO:0008198;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 storage protein#PC00210 GORGO|Ensembl=ENSGGOG00000006145.3|UniProtKB=G3QTI6 G3QTI6 LOC101130677 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016276.3|UniProtKB=G3RJJ5 G3RJJ5 PIWIL4 PTHR22891:SF43 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 4 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;RNA binding#GO:0003723 negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;male gamete generation#GO:0048232;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609 intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000011949.3|UniProtKB=A0A2I2ZMK4 A0A2I2ZMK4 RIPOR1 PTHR15829:SF1 PROTEIN KINASE PKN/PRK1, EFFECTOR RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000036532.1|UniProtKB=G3RSD9 G3RSD9 AGO4 PTHR22891:SF26 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-4 nuclease activity#GO:0004518;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded RNA binding#GO:0003727;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;regulation of cellular process#GO:0050794;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000011603.3|UniProtKB=G3R7H9 G3R7H9 C5H6orf163 PTHR34645:SF1 SIMILAR TO HYPOTHETICAL PROTEIN SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 163 GORGO|Ensembl=ENSGGOG00000001169.3|UniProtKB=A0A2I2ZUI0 A0A2I2ZUI0 HECTD4 PTHR46435:SF1 E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED chemical homeostasis#GO:0048878;carbohydrate homeostasis#GO:0033500;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000025889.2|UniProtKB=G3S3H2 G3S3H2 DYNLT4 PTHR21255:SF55 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 4 binding#GO:0005488;protein binding#GO:0005515 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000010067.4|UniProtKB=G3R3J6 G3R3J6 STK32B PTHR24356:SF157 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 32B phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000037681.1|UniProtKB=A0A2I2Y229 A0A2I2Y229 PTHR10797:SF50 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT POLY(A)-SPECIFIC RIBONUCLEASE 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;CCR4-NOT complex#GO:0030014 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000007725.3|UniProtKB=G3QXL0 G3QXL0 SRFBP1 PTHR23325:SF1 SERUM RESPONSE FACTOR-BINDING SERUM RESPONSE FACTOR-BINDING PROTEIN 1 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribonucleoprotein complex#GO:1990904;90S preribosome#GO:0030686;preribosome#GO:0030684;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015601.3|UniProtKB=G3RHU7 G3RHU7 EPHB6 PTHR46877:SF15 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 6 transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501 dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000015108.3|UniProtKB=A0A2I2Z6C8 A0A2I2Z6C8 FGF8 PTHR11486:SF3 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 8 receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;pattern specification process#GO:0007389;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;dorsal/ventral pattern formation#GO:0009953;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;regionalization#GO:0003002;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 GORGO|Ensembl=ENSGGOG00000012748.3|UniProtKB=G3RAG4 G3RAG4 LOC101143885 PTHR10502:SF133 ANNEXIN ANNEXIN A8-RELATED anion binding#GO:0043168;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;binding#GO:0005488;ion binding#GO:0043167;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786 endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component organization#GO:0016043;organelle organization#GO:0006996;vesicle organization#GO:0016050;endosome organization#GO:0007032;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;sarcolemma#GO:0042383;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000010568.3|UniProtKB=G3S4A4 G3S4A4 PRDM12 PTHR16515:SF20 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 12 enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515 cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000025149.2|UniProtKB=G3SIV7 G3SIV7 PTHR47226:SF1 C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4A C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4B regulation of biological process#GO:0050789;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;blood circulation#GO:0008015;response to stimulus#GO:0050896;inflammatory response#GO:0006954;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;defense response#GO:0006952;system process#GO:0003008;acute inflammatory response#GO:0002526 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000037404.1|UniProtKB=A0A2I2YSS5 A0A2I2YSS5 PTHR23267:SF399 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000008094.3|UniProtKB=G3SFI2 G3SFI2 PTPRS PTHR19134:SF542 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;cell communication#GO:0007154;synapse organization#GO:0050808;cell adhesion#GO:0007155;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043 protein phosphatase#PC00195;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000041636.1|UniProtKB=G3S031 G3S031 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E10-RELATED GORGO|Ensembl=ENSGGOG00000017031.3|UniProtKB=G3RLH4 G3RLH4 GZMA PTHR24271:SF69 KALLIKREIN-RELATED GRANZYME A serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 programmed cell death#GO:0012501;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell death#GO:0008219;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell communication#GO:0007154;protein metabolic process#GO:0019538;signal transduction#GO:0007165;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000012064.3|UniProtKB=G3R8Q6 G3R8Q6 LOC101135564 PTHR13325:SF3 PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 membrane protein proteolysis#GO:0033619;regulation of biological process#GO:0050789;regulation of response to endoplasmic reticulum stress#GO:1905897;cellular process#GO:0009987;primary metabolic process#GO:0044238;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;proteolysis#GO:0006508;metabolic process#GO:0008152;regulation of response to stress#GO:0080134;regulation of cellular response to stress#GO:0080135;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011886.3|UniProtKB=G3S3J1 G3S3J1 SPTLC2 PTHR13693:SF79 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 ceramide biosynthetic process#GO:0046513;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 transaminase#PC00216 GORGO|Ensembl=ENSGGOG00000040501.1|UniProtKB=G3S3D6 G3S3D6 LOC101138239 PTHR18860:SF7 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA_DELTA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;PI3 kinase pathway#P00048>14-3-3#P01206;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624 GORGO|Ensembl=ENSGGOG00000025043.2|UniProtKB=A0A2I2ZQA7 A0A2I2ZQA7 DYNLL2 PTHR11886:SF113 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 2, CYTOPLASMIC microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000040556.1|UniProtKB=A0A2I2YKB6 A0A2I2YKB6 TTC6 PTHR44858:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 6 TETRATRICOPEPTIDE REPEAT DOMAIN 6 GORGO|Ensembl=ENSGGOG00000026208.2|UniProtKB=G3SJ28 G3SJ28 GPBAR1 PTHR24246:SF31 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR G PROTEIN-COUPLED BILE ACID RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000014209.3|UniProtKB=G3REA0 G3REA0 NUP210L PTHR23019:SF1 NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210-LIKE nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006428.4|UniProtKB=G3QU91 G3QU91 GYS2 PTHR10176:SF1 GLYCOGEN SYNTHASE GLYCOGEN [STARCH] SYNTHASE, LIVER glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;generation of precursor metabolites and energy#GO:0006091;glycogen biosynthetic process#GO:0005978;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112;glucan biosynthetic process#GO:0009250 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Glycogen synthase D#P00709 GORGO|Ensembl=ENSGGOG00000007618.3|UniProtKB=G3QXB7 G3QXB7 DAP3 PTHR12810:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN MS29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000023604.2|UniProtKB=G3S3Q1 G3S3Q1 PTHR15438:SF5 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX INTERACTING PROTEIN FAMILY MEMBER B3-RELATED GORGO|Ensembl=ENSGGOG00000013293.3|UniProtKB=G3RBV8 G3RBV8 CEP128 PTHR46657:SF1 CENTROSOMAL PROTEIN OF 128 KDA CENTROSOMAL PROTEIN 128 cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000010372.3|UniProtKB=G3RMY6 G3RMY6 DBI PTHR23310:SF54 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000012573.3|UniProtKB=G3RA16 G3RA16 CTU2 PTHR20882:SF14 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;transferase activity#GO:0016740;catalytic activity#GO:0003824 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA thio-modification#GO:0034227;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA wobble position uridine thiolation#GO:0002143;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000010266.3|UniProtKB=G3R434 G3R434 PTHR12455:SF0 NUCLEOLAR COMPLEX PROTEIN 4 NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012099.4|UniProtKB=G3R8U1 G3R8U1 DDHD1 PTHR23509:SF32 PA-PL1 PHOSPHOLIPASE FAMILY PHOSPHOLIPASE DDHD1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phospholipase#PC00186;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000038251.1|UniProtKB=A0A2I2ZL34 A0A2I2ZL34 CNP PTHR10156:SF0 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185 GORGO|Ensembl=ENSGGOG00000002220.3|UniProtKB=G3QIH6 G3QIH6 HOXA7 PTHR45659:SF12 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A7 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000013635.3|UniProtKB=G3RCR7 G3RCR7 SHISAL1 PTHR31395:SF11 SHISA PROTEIN SHISA-LIKE-1 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000038979.1|UniProtKB=A0A2I2ZHT0 A0A2I2ZHT0 PPP2R5E PTHR10257:SF80 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT EPSILON ISOFORM enzyme activator activity#GO:0008047;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888 cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;EGF receptor signaling pathway#P00018>PP2A#P00547 GORGO|Ensembl=ENSGGOG00000039515.1|UniProtKB=A0A2I2ZP93 A0A2I2ZP93 C4H5orf24 PTHR31894:SF0 UPF0461 PROTEIN C5ORF24 UPF0461 PROTEIN C5ORF24 GORGO|Ensembl=ENSGGOG00000036916.1|UniProtKB=G3SC61 G3SC61 PTHR46029:SF4 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 2 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;transcription coactivator activity#GO:0003713;binding#GO:0005488;transcription regulator activity#GO:0140110;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000000667.3|UniProtKB=G3QEG2 G3QEG2 LOC101144017 PTHR11537:SF28 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 3 metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267 potassium ion transport#GO:0006813;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811 axon#GO:0030424;transmembrane transporter complex#GO:1902495;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886 ion channel#PC00133;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000015781.3|UniProtKB=G3S4Q4 G3S4Q4 WAPL PTHR22100:SF13 WINGS APART-LIKE PROTEIN HOMOLOG WINGS APART-LIKE PROTEIN HOMOLOG GORGO|Ensembl=ENSGGOG00000007893.3|UniProtKB=A0A2I2Z7F5 A0A2I2Z7F5 KY PTHR46333:SF3 CYTOKINESIS PROTEIN 3 KYPHOSCOLIOSIS PEPTIDASE cell junction organization#GO:0034330;muscle structure development#GO:0061061;cellular process#GO:0009987;cellular component organization#GO:0016043;neuromuscular junction development#GO:0007528;animal organ development#GO:0048513;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;muscle organ development#GO:0007517 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000044071.1|UniProtKB=A0A2I2YCZ7 A0A2I2YCZ7 MSH4 PTHR11361:SF21 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER MUTS PROTEIN HOMOLOG 4 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488 reproductive process#GO:0022414;homologous recombination#GO:0035825;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;organelle fission#GO:0048285;sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000015520.3|UniProtKB=A0A2I2Z1R6 A0A2I2Z1R6 NXN PTHR46472:SF1 NUCLEOREDOXIN NUCLEOREDOXIN disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of response to stimulus#GO:0048583;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;regulation of protein modification process#GO:0031399;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of signaling#GO:0023051;negative regulation of protein ubiquitination#GO:0031397;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of post-translational protein modification#GO:1901873 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000012813.3|UniProtKB=G3RAN1 G3RAN1 TRERF1 PTHR16089:SF19 REST COREPRESSOR COREST PROTEIN-RELATED TRANSCRIPTIONAL-REGULATING FACTOR 1 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000009350.3|UniProtKB=G3RP88 G3RP88 CRTAM PTHR47118:SF1 CYTOTOXIC AND REGULATORY T-CELL MOLECULE CYTOTOXIC AND REGULATORY T-CELL MOLECULE protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cell recognition#GO:0008037;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;detection of stimulus#GO:0051606;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of natural killer cell mediated cytotoxicity#GO:0042269;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000014501.3|UniProtKB=G3REY9 G3REY9 MRPL57 PTHR14520:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 63 LARGE RIBOSOMAL SUBUNIT PROTEIN ML63 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000009848.3|UniProtKB=G3R313 G3R313 STT3A PTHR13872:SF43 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein modification process#GO:0036211;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;carbohydrate derivative biosynthetic process#GO:1901137 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000012715.3|UniProtKB=G3RAC8 G3RAC8 CORT PTHR22980:SF6 CORTISTATIN CENTROMERE PROTEIN S binding#GO:0005488;chromatin binding#GO:0003682 cell cycle#GO:0007049;primary metabolic process#GO:0044238;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;DNA replication#GO:0006260;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;DNA-templated DNA replication#GO:0006261;organelle fission#GO:0048285;organelle organization#GO:0006996;resolution of meiotic recombination intermediates#GO:0000712;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;Fanconi anaemia nuclear complex#GO:0043240;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 neuropeptide#PC00162;peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000016175.3|UniProtKB=G3RJA8 G3RJA8 MAST3 PTHR24356:SF140 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 3 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000027499.2|UniProtKB=G3SGX5 G3SGX5 ISCA2 PTHR43011:SF1 IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;iron-sulfur cluster binding#GO:0051536;metal ion binding#GO:0046872;iron ion binding#GO:0005506 iron-sulfur cluster assembly#GO:0016226;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular component biogenesis#GO:0044085;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000012259.3|UniProtKB=A0A2I2YZB0 A0A2I2YZB0 GPR137 PTHR15146:SF5 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137 regulation of intracellular signal transduction#GO:1902531;regulation of myeloid cell differentiation#GO:0045637;regulation of signaling#GO:0023051;regulation of bone resorption#GO:0045124;positive regulation of signaling#GO:0023056;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;regulation of hemopoiesis#GO:1903706;regulation of tissue remodeling#GO:0034103;positive regulation of TOR signaling#GO:0032008;negative regulation of multicellular organismal process#GO:0051241;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;regulation of bone remodeling#GO:0046850;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966 cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011490.3|UniProtKB=G3R779 G3R779 FAM149A PTHR31997:SF2 AGAP003710-PA PROTEIN FAM149A GORGO|Ensembl=ENSGGOG00000040745.1|UniProtKB=A0A2I2Y4S0 A0A2I2Y4S0 PTHR13082:SF2 SAP18 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000004553.2|UniProtKB=G3QPG9 G3QPG9 DIRAS1 PTHR24070:SF213 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000011041.3|UniProtKB=G3R626 G3R626 TMEM163 PTHR31937:SF2 TRANSMEMBRANE PROTEIN 163 TRANSMEMBRANE PROTEIN 163 cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;ion binding#GO:0043167 organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 GORGO|Ensembl=ENSGGOG00000027172.2|UniProtKB=G3S9Y5 G3S9Y5 DCUN1D2 PTHR12281:SF16 RP42 RELATED DCN1-LIKE PROTEIN 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;binding#GO:0005488;protein binding#GO:0005515 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein metabolic process#GO:0051247;regulation of protein modification process#GO:0031399;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000016342.3|UniProtKB=G3RJQ3 G3RJQ3 MLH1 PTHR10073:SF57 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH1 nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;cellular response to stress#GO:0033554;immune system development#GO:0002520;anatomical structure development#GO:0048856;system development#GO:0048731;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;developmental process#GO:0032502;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;multicellular organismal process#GO:0032501;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000000636.3|UniProtKB=G3QED4 G3QED4 BROX PTHR23032:SF13 BRO1 DOMAIN-CONTAINING PROTEIN BROX BRO1 DOMAIN-CONTAINING PROTEIN BROX GORGO|Ensembl=ENSGGOG00000004091.4|UniProtKB=A0A2I2Y1U8 A0A2I2Y1U8 NOL4 PTHR12449:SF17 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4 GORGO|Ensembl=ENSGGOG00000041883.1|UniProtKB=A0A2I2YFG8 A0A2I2YFG8 LSM8 PTHR15588:SF9 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;U6 snRNP#GO:0005688;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525 RNA splicing factor#PC00148;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000015191.3|UniProtKB=G3RGR7 G3RGR7 SCAMP1 PTHR10687:SF8 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 1 transport#GO:0006810;secretion by cell#GO:0032940;exocytosis#GO:0006887;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000024000.2|UniProtKB=G3RTV4 G3RTV4 PLP2 PTHR22776:SF4 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PROTEOLIPID PROTEIN 2 response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response#GO:0006955 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008564.3|UniProtKB=A0A2I2YRS0 A0A2I2YRS0 TAF12 PTHR12264:SF21 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transferase complex#GO:1990234;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 GORGO|Ensembl=ENSGGOG00000027426.2|UniProtKB=G3RWG3 G3RWG3 TMEM67 PTHR21274:SF2 MECKELIN MECKELIN organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;cilium#GO:0005929 GORGO|Ensembl=ENSGGOG00000016795.3|UniProtKB=G3RKV5 G3RKV5 RFX5 PTHR12619:SF18 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000006234.3|UniProtKB=G3QTR6 G3QTR6 MRPS34 PTHR28589:SF1 28S RIBOSOMAL PROTEIN S34, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS34 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000011169.3|UniProtKB=G3R6E0 G3R6E0 SETD3 PTHR13271:SF159 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE ACTIN-HISTIDINE N-METHYLTRANSFERASE lysine N-methyltransferase activity#GO:0016278;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 regulation of muscle system process#GO:0090257;regulation of system process#GO:0044057;regulation of muscle contraction#GO:0006937;regulation of biological process#GO:0050789;regulation of smooth muscle contraction#GO:0006940;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 methyltransferase#PC00155;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000000892.2|UniProtKB=G3QF15 G3QF15 OR51B5 PTHR26450:SF76 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000007190.3|UniProtKB=G3QW84 G3QW84 FAM24B PTHR35860:SF5 PROTEIN FAM24B PROTEIN FAM24B GORGO|Ensembl=ENSGGOG00000041061.1|UniProtKB=A0A2I2ZV34 A0A2I2ZV34 KANK4 PTHR24168:SF24 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 4 regulation of actin filament length#GO:0030832;negative regulation of protein polymerization#GO:0032272;regulation of biological quality#GO:0065008;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000003624.3|UniProtKB=G3QM36 G3QM36 CCNI PTHR10177:SF187 CYCLINS CYCLIN-I enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000015690.3|UniProtKB=G3RI24 G3RI24 SPRING1 PTHR13481:SF0 SREBP REGULATING GENE PROTEIN SREBP REGULATING GENE PROTEIN GORGO|Ensembl=ENSGGOG00000013532.3|UniProtKB=G3RCG9 G3RCG9 RAB3C PTHR47980:SF15 LD44762P RAS-RELATED PROTEIN RAB-3C protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488 transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192 synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;exocytic vesicle#GO:0070382;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell junction#GO:0030054 Synaptic vesicle trafficking#P05734>Rab3A#P05780 GORGO|Ensembl=ENSGGOG00000006910.3|UniProtKB=G3SDN4 G3SDN4 HMGN3 PTHR23087:SF2 NONHISTONE CHROMOSOMAL PROTEIN HMG HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 3 chromatin binding#GO:0003682;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000036888.1|UniProtKB=A0A2I2YYA8 A0A2I2YYA8 ZNF747 PTHR24381:SF451 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 747 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000042865.1|UniProtKB=A0A2I2Y8M1 A0A2I2Y8M1 PTHR23411:SF38 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;antigen binding#GO:0003823 defense response to other organism#GO:0098542;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;antibacterial humoral response#GO:0019731;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;immune effector process#GO:0002252;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;defense response to bacterium#GO:0042742;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;complement activation#GO:0006956;immune response#GO:0006955;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;response to bacterium#GO:0009617;regulation of immune response#GO:0050776 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000007421.3|UniProtKB=G3QWU2 G3QWU2 ASCL2 PTHR13935:SF62 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;sensory organ development#GO:0007423;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000011883.3|UniProtKB=G3R888 G3R888 TRADD PTHR14913:SF0 TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219;programmed cell death#GO:0012501;cell communication#GO:0007154;apoptotic signaling pathway#GO:0097190;cell surface receptor signaling pathway#GO:0007166 protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235 Apoptosis signaling pathway#P00006>TRADD#P00319 GORGO|Ensembl=ENSGGOG00000003951.4|UniProtKB=G3QMY0 G3QMY0 EXOC4 PTHR14146:SF4 EXOCYST COMPLEX COMPONENT 4 EXOCYST COMPLEX COMPONENT 4 vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization#GO:0051234;exocytosis#GO:0006887;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;export from cell#GO:0140352;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;secretion by cell#GO:0032940;trans-synaptic signaling#GO:0099537 vesicle tethering complex#GO:0099023;cell junction#GO:0030054;cytoplasm#GO:0005737;exocyst#GO:0000145;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;growth cone#GO:0030426;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000038544.1|UniProtKB=A0A2I2Y2X0 A0A2I2Y2X0 CLDN2 PTHR12002:SF110 CLAUDIN CLAUDIN-2 paracellular tight junction channel activity#GO:0160187;transporter activity#GO:0005215 cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;establishment of localization#GO:0051234;cell adhesion#GO:0007155;cell-cell junction organization#GO:0045216;transport#GO:0006810;cell-cell junction assembly#GO:0007043 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000014361.3|UniProtKB=A0A2I2YZM1 A0A2I2YZM1 JMJD6 PTHR12480:SF32 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6 localization#GO:0051179;import into cell#GO:0098657;endocytosis#GO:0006897;establishment of localization#GO:0051234;phagocytosis#GO:0006909;transport#GO:0006810 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000006844.3|UniProtKB=G3QVD6 G3QVD6 CLNK PTHR14098:SF2 SH2 DOMAIN CONTAINING PROTEIN CYTOKINE-DEPENDENT HEMATOPOIETIC CELL LINKER protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular signal transduction#GO:0035556;immune system process#GO:0002376;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell activation#GO:0001775;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;leukocyte activation#GO:0045321;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell surface receptor signaling pathway#GO:0007166;myeloid leukocyte activation#GO:0002274;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027980.2|UniProtKB=G3RRK1 G3RRK1 PTHR19971:SF32 SIGNAL-REGULATORY PROTEIN BETA SIGNAL-REGULATORY PROTEIN BETA-1 positive regulation of cellular component organization#GO:0051130;positive regulation of lymphocyte activation#GO:0051251;regulation of leukocyte activation#GO:0002694;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of cell adhesion#GO:0045785;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of endocytosis#GO:0030100;positive regulation of leukocyte activation#GO:0002696;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of T cell activation#GO:0050870;positive regulation of endocytosis#GO:0045807;regulation of cell adhesion#GO:0030155;regulation of T cell activation#GO:0050863;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of cell activation#GO:0050867 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009644.3|UniProtKB=G3R2H2 G3R2H2 ZMYM6 PTHR45736:SF9 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 6 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000006211.3|UniProtKB=G3QTP4 G3QTP4 PAEP PTHR11430:SF117 LIPOCALIN GLYCODELIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 GORGO|Ensembl=ENSGGOG00000005275.3|UniProtKB=G3QRC3 G3QRC3 HTR6 PTHR24247:SF236 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 6 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537 dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 GORGO|Ensembl=ENSGGOG00000022701.2|UniProtKB=G3RM79 G3RM79 LOC101145215 PTHR24377:SF604 IP01015P-RELATED ZINC FINGER PROTEIN 285 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000038512.1|UniProtKB=A0A2I2Y6K9 A0A2I2Y6K9 EGR1 PTHR23235:SF42 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cognition#GO:0050890;nervous system process#GO:0050877;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;system process#GO:0003008;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248 Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#G06672;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>EGR#P05931;Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#G06887;CCKR signaling map#P06959>EGR1#P07192;Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#P06837 GORGO|Ensembl=ENSGGOG00000002922.3|UniProtKB=G3SJF9 G3SJF9 CCDC93 PTHR16441:SF10 FIDIPIDINE COILED-COIL DOMAIN-CONTAINING PROTEIN 93 intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192 protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000004111.3|UniProtKB=G3QNC1 G3QNC1 RPL35 PTHR45722:SF37 60S RIBOSOMAL PROTEIN L35 LARGE RIBOSOMAL SUBUNIT PROTEIN UL29 RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000025440.2|UniProtKB=G3RW40 G3RW40 TDO2 PTHR10138:SF0 TRYPTOPHAN 2,3-DIOXYGENASE TRYPTOPHAN 2,3-DIOXYGENASE binding#GO:0005488;catalytic activity#GO:0003824;heme binding#GO:0020037;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000007277.3|UniProtKB=G3QWG6 G3QWG6 PTHR47437:SF2 JNK-INTERACTING PROTEIN 1-LIKE PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 2 structural molecule activity#GO:0005198;MAP kinase scaffold activity#GO:0005078;protein complex scaffold activity#GO:0140378;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000000618.3|UniProtKB=G3QEB7 G3QEB7 F9 PTHR24278:SF31 COAGULATION FACTOR COAGULATION FACTOR IX catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 biosynthetic process#GO:0009058;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;coagulation#GO:0050817;response to stress#GO:0006950;response to wounding#GO:0009611;blood coagulation#GO:0007596;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;zymogen activation#GO:0031638;primary metabolic process#GO:0044238;hemostasis#GO:0007599;wound healing#GO:0042060;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 Blood coagulation#P00011>FIX#P00444;Blood coagulation#P00011>FIXa#P00422;Blood coagulation#P00011>FXIa#P00434;Blood coagulation#P00011>FXI#P00460 GORGO|Ensembl=ENSGGOG00000039808.1|UniProtKB=A0A2I2Z3P9 A0A2I2Z3P9 PTHR19441:SF17 WAP four-disulfide core domain protein PROTEIN WFDC10B peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;response to external stimulus#GO:0009605;defense response#GO:0006952;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000004490.3|UniProtKB=A0A2I2ZXP5 A0A2I2ZXP5 CLEC7A PTHR47218:SF1 C-TYPE LECTIN DOMAIN FAMILY 7 MEMBER A C-TYPE LECTIN DOMAIN FAMILY 7 MEMBER A polysaccharide binding#GO:0030247;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246 innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;defense response#GO:0006952;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;response to external stimulus#GO:0009605;phagocytosis#GO:0006909;transport#GO:0006810;regulation of response to stimulus#GO:0048583;response to other organism#GO:0051707;positive regulation of immune effector process#GO:0002699;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of immune effector process#GO:0002697;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;cell recognition#GO:0008037;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;import into cell#GO:0098657;defense response to other organism#GO:0098542;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of cytokine production involved in immune response#GO:0002718;regulation of signaling#GO:0023051;endocytosis#GO:0006897;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 GORGO|Ensembl=ENSGGOG00000022771.2|UniProtKB=G3RZJ1 G3RZJ1 LOC101132458 PTHR15336:SF6 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 6-LIKE, MITOCHONDRIAL generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex III#GO:0045275;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803 reductase#PC00198;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000004457.3|UniProtKB=G3QP86 G3QP86 COLQ PTHR24023:SF861 COLLAGEN ALPHA ACETYLCHOLINESTERASE COLLAGENIC TAIL PEPTIDE structural molecule activity#GO:0005198;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;extracellular matrix structural constituent#GO:0005201;heparin binding#GO:0008201 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000012900.3|UniProtKB=G3S5V1 G3S5V1 ATXN7 PTHR15117:SF2 ATAXIN 7 RELATED ATAXIN-7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;microtubule cytoskeleton organization#GO:0000226;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA biosynthetic process#GO:1902680;cytoskeleton organization#GO:0007010;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000002645.3|UniProtKB=G3QJL3 G3QJL3 RXFP2 PTHR24372:SF72 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN RECEPTOR 2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000004037.3|UniProtKB=G3QN55 G3QN55 TCL1A PTHR14060:SF4 PROTEIN P13 MTCP-1 T-CELL LEUKEMIA_LYMPHOMA PROTEIN 1A enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000013391.3|UniProtKB=G3RUW9 G3RUW9 METTL17 PTHR21320:SF3 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED RIBOSOME ASSEMBLY PROTEIN METTL17, MITOCHONDRIAL chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000037265.1|UniProtKB=A0A2I2YSI3 A0A2I2YSI3 PTHR11655:SF31 60S/50S RIBOSOMAL PROTEIN L6/L9 LARGE RIBOSOMAL SUBUNIT PROTEIN UL6 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000007247.3|UniProtKB=G3SCX0 G3SCX0 PTHR24393:SF62 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000016980.3|UniProtKB=G3RLD0 G3RLD0 HSPA12B PTHR14187:SF39 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12B GORGO|Ensembl=ENSGGOG00000016449.3|UniProtKB=A0A2I2YEF1 A0A2I2YEF1 METTL14 PTHR13107:SF0 N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT N(6)-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT METTL14 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;mRNA metabolic process#GO:0016071;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;RNA modification#GO:0009451;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000006968.3|UniProtKB=G3QVP0 G3QVP0 BSPRY PTHR24103:SF568 E3 UBIQUITIN-PROTEIN LIGASE TRIM B BOX AND SPRY DOMAIN-CONTAINING PROTEIN aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000000532.3|UniProtKB=G3S9T4 G3S9T4 ATP6AP2 PTHR13351:SF5 RENIN RECEPTOR RENIN RECEPTOR positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026806.2|UniProtKB=G3S0Z1 G3S0Z1 PTHR11886:SF86 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000004718.3|UniProtKB=G3S841 G3S841 EIF4E PTHR11960:SF14 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E translation initiation factor activity#GO:0003743;RNA binding#GO:0003723;translation factor activity#GO:0180051;nucleic acid binding#GO:0003676;binding#GO:0005488 translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 CCKR signaling map#P06959>EIF4E#P07094;p38 MAPK pathway#P05918>eIF4E#P06024 GORGO|Ensembl=ENSGGOG00000002757.3|UniProtKB=G3QJW1 G3QJW1 LOC101152996 PTHR15420:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 6.4 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 10 mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000013927.3|UniProtKB=G3RDI2 G3RDI2 IRF1 PTHR11949:SF3 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000006635.3|UniProtKB=G3QUU0 G3QUU0 PPEF2 PTHR45668:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 2 binding#GO:0005488;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;protein binding#GO:0005515 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000008921.3|UniProtKB=G3SDR9 G3SDR9 HMGXB3 PTHR17609:SF2 HMG DOMAIN-CONTAINING PROTEIN 3 HMG DOMAIN-CONTAINING PROTEIN 3 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 GORGO|Ensembl=ENSGGOG00000000868.3|UniProtKB=G3QEZ6 G3QEZ6 MEAK7 PTHR23354:SF131 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED MTOR-ASSOCIATED PROTEIN MEAK7 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to oxidative stress#GO:0006979;TOR signaling#GO:0031929;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000012175.3|UniProtKB=G3R904 G3R904 QPRT PTHR32179:SF3 NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nicotinamide nucleotide metabolic process#GO:0046496;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524 GORGO|Ensembl=ENSGGOG00000005472.3|UniProtKB=G3SI71 G3SI71 RAB5C PTHR47978:SF63 FAMILY NOT NAMED SMALL MONOMERIC GTPASE guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 small GTPase#PC00208 GORGO|Ensembl=ENSGGOG00000015198.3|UniProtKB=G3S2M6 G3S2M6 NTPCR PTHR43146:SF1 CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000043049.1|UniProtKB=A0A2I2YFJ2 A0A2I2YFJ2 RAB2A PTHR47979:SF12 DRAB11-RELATED RAS-RELATED PROTEIN RAB-2A carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 small GTPase#PC00208;G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000009976.3|UniProtKB=A0A2I2ZYR1 A0A2I2ZYR1 QSOX1 PTHR22897:SF6 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE 1 oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;disulfide oxidoreductase activity#GO:0015036;isomerase activity#GO:0016853;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;extracellular matrix assembly#GO:0085029;gene expression#GO:0010467;protein maturation#GO:0051604;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein folding#GO:0006457 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176;oxidase#PC00175 GORGO|Ensembl=ENSGGOG00000038227.1|UniProtKB=G3RLT1 G3RLT1 PTHR43880:SF1 ALCOHOL DEHYDROGENASE ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH1B catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;zinc ion binding#GO:0008270;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;cation binding#GO:0043169;metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 carboxylic acid metabolic process#GO:0019752;cellular detoxification of aldehyde#GO:0110095;monocarboxylic acid metabolic process#GO:0032787;regulation of hormone levels#GO:0010817;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;olefinic compound metabolic process#GO:0120254;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;regulation of biological quality#GO:0065008;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;catabolic process#GO:0009056;retinol metabolic process#GO:0042572;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;hormone metabolic process#GO:0042445;aldehyde catabolic process#GO:0046185;biological regulation#GO:0065007;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000002805.3|UniProtKB=G3QK01 G3QK01 KRT75 PTHR45616:SF13 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 75 structural molecule activity#GO:0005198 animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;epidermis development#GO:0008544;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;cellular process#GO:0009987;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000005133.3|UniProtKB=A0A2I2ZPI9 A0A2I2ZPI9 CADM3 PTHR45889:SF5 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 3 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 GORGO|Ensembl=ENSGGOG00000041079.1|UniProtKB=A0A2I2Y4Y3 A0A2I2Y4Y3 PTHR10938:SF9 TRANSLATION INITIATION FACTOR IF-3 TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000017194.3|UniProtKB=G3RLW8 G3RLW8 TMEM168 PTHR14437:SF2 TRANSMEMBRANE PROTEIN 168 TRANSMEMBRANE PROTEIN 168 GORGO|Ensembl=ENSGGOG00000015027.3|UniProtKB=G3RGC3 G3RGC3 ATP6V1E1 PTHR45715:SF2 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED V-TYPE PROTON ATPASE SUBUNIT E 1 monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting two-sector ATPase complex#GO:0016469 GORGO|Ensembl=ENSGGOG00000000889.3|UniProtKB=G3QF14 G3QF14 GPX3 PTHR11592:SF32 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 3 antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 hydrogen peroxide metabolic process#GO:0042743;cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to stress#GO:0033554;reactive oxygen species metabolic process#GO:0072593;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176;peroxidase#PC00180 GORGO|Ensembl=ENSGGOG00000001218.3|UniProtKB=G3QFW7 G3QFW7 RTP1 PTHR14402:SF19 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 protein targeting#GO:0006605;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;localization within membrane#GO:0051668;detection of chemical stimulus involved in sensory perception#GO:0050907;membrane organization#GO:0061024;multicellular organismal process#GO:0032501;protein insertion into membrane#GO:0051205;response to chemical#GO:0042221;cellular process#GO:0009987;establishment of protein localization#GO:0045184;detection of stimulus#GO:0051606;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;detection of stimulus involved in sensory perception#GO:0050906;intracellular protein localization#GO:0008104;system process#GO:0003008;establishment of localization#GO:0051234;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;cellular component organization or biogenesis#GO:0071840;sensory perception of chemical stimulus#GO:0007606;protein targeting to membrane#GO:0006612;sensory perception of taste#GO:0050909 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000022330.2|UniProtKB=G3RT83 G3RT83 WFIKKN2 PTHR45938:SF7 ACP24A4-RELATED WAP, KAZAL, IMMUNOGLOBULIN, KUNITZ AND NTR DOMAIN-CONTAINING PROTEIN 2 molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955;signaling receptor regulator activity#GO:0030545;transforming growth factor beta binding#GO:0050431;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;protein binding#GO:0005515;growth factor binding#GO:0019838;binding#GO:0005488 response to transforming growth factor beta#GO:0071559;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000009913.3|UniProtKB=G3R361 G3R361 PTHR46481:SF15 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 GORGO|Ensembl=ENSGGOG00000001103.3|UniProtKB=A0A2I2Z536 A0A2I2Z536 PTHR23359:SF184 NUCLEOTIDE KINASE ADENYLATE KINASE ACTIVE SITE LID DOMAIN-CONTAINING PROTEIN kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550 ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000012377.3|UniProtKB=G3R9J6 G3R9J6 TNIP3 PTHR31882:SF2 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 3 response to lipopolysaccharide#GO:0032496;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;biological process involved in interspecies interaction between organisms#GO:0044419;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;cellular response to molecule of bacterial origin#GO:0071219;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of canonical NF-kappaB signal transduction#GO:0043122;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;response to bacterium#GO:0009617;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207 GORGO|Ensembl=ENSGGOG00000010783.3|UniProtKB=G3S458 G3S458 LTBP4 PTHR24034:SF43 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 4 cytokine binding#GO:0019955;growth factor binding#GO:0019838;protein binding#GO:0005515;transforming growth factor beta binding#GO:0050431;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 GORGO|Ensembl=ENSGGOG00000041022.1|UniProtKB=A0A2I2ZP24 A0A2I2ZP24 TRIM58 PTHR24103:SF393 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM58 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 regulation of biological process#GO:0050789;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;immune system process#GO:0002376;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000023190.2|UniProtKB=G3RYL1 G3RYL1 PTHR24377:SF741 IP01015P-RELATED ZINC FINGER PROTEIN 611 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022068.2|UniProtKB=A0A2I2Z5Y8 A0A2I2Z5Y8 LOC101125167 PTHR22055:SF4 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN CASEIN KINASE SUBSTRATE PHOSPHOPROTEIN PP28 DOMAIN-CONTAINING PROTEIN cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000006542.3|UniProtKB=G3QUJ9 G3QUJ9 PTHR14795:SF0 HELICASE RELATED TRANSMEMBRANE PROTEIN 62 RNA helicase#PC00032;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000026287.2|UniProtKB=A0A2I2Y5J3 A0A2I2Y5J3 PTHR10657:SF30 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE catalytic activity, acting on a protein#GO:0140096;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000044024.1|UniProtKB=A0A2I2Y4V4 A0A2I2Y4V4 TASP1 PTHR10188:SF8 L-ASPARAGINASE THREONINE ASPARTASE 1 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 GORGO|Ensembl=ENSGGOG00000024589.2|UniProtKB=G3RUG8 G3RUG8 PTHR20982:SF13 RIBOSOME RECYCLING FACTOR SUBFAMILY NOT NAMED binding#GO:0005488;ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;translational termination#GO:0006415;translation#GO:0006412;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;mitochondrial gene expression#GO:0140053 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 translation release factor#PC00225 GORGO|Ensembl=ENSGGOG00000004753.3|UniProtKB=G3QQ00 G3QQ00 SLC39A9 PTHR16133:SF5 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED ZINC TRANSPORTER ZIP9 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000025635.2|UniProtKB=G3S2N2 G3S2N2 ASPM PTHR22706:SF1 ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES binding#GO:0005488;calmodulin binding#GO:0005516;protein binding#GO:0005515 organelle organization#GO:0006996;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;meiotic cell cycle#GO:0051321;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;organelle localization#GO:0051640;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;spindle localization#GO:0051653;localization#GO:0051179 spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000007330.3|UniProtKB=G3QWL3 G3QWL3 GLOD5 PTHR21366:SF14 GLYOXALASE FAMILY PROTEIN GLYOXALASE DOMAIN-CONTAINING PROTEIN 5 GORGO|Ensembl=ENSGGOG00000034901.2|UniProtKB=G3SKW6 G3SKW6 CIP2A PTHR23161:SF2 PROTEIN CIP2A PROTEIN CIP2A phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;organelle organization#GO:0006996;cellular component organization#GO:0016043;response to stress#GO:0006950;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 GORGO|Ensembl=ENSGGOG00000025576.2|UniProtKB=G3RM24 G3RM24 IFNB1 PTHR11691:SF73 TYPE I INTERFERON INTERFERON BETA cytokine activity#GO:0005125;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;T cell activation#GO:0042110;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;natural killer cell activation#GO:0030101;cell surface receptor signaling pathway#GO:0007166;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;humoral immune response#GO:0006959;B cell activation#GO:0042113;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;lymphocyte activation involved in immune response#GO:0002285;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;T cell activation involved in immune response#GO:0002286;lymphocyte activation#GO:0046649;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;adaptive immune response#GO:0002250;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interferon superfamily#PC00127;cytokine#PC00083 Toll receptor signaling pathway#P00054>Gene trancription#G01550 GORGO|Ensembl=ENSGGOG00000024312.2|UniProtKB=A0A2I2Y2S2 A0A2I2Y2S2 OPRM1 PTHR24229:SF7 NEUROPEPTIDES RECEPTOR MU-TYPE OPIOID RECEPTOR protein binding#GO:0005515;molecular transducer activity#GO:0060089;neuropeptide receptor activity#GO:0008188;binding#GO:0005488;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 system process#GO:0003008;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;sensory perception of pain#GO:0019233;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Opioid proopiomelanocortin pathway#P05917>Mu or Delta receptor#P06004;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Enkephalin release#P05913>GPCR (s)#P05975;Opioid proenkephalin pathway#P05915>Mu or Delta receptor#P05985;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 GORGO|Ensembl=ENSGGOG00000013399.3|UniProtKB=G3RC48 G3RC48 HES4 PTHR10985:SF157 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 GORGO|Ensembl=ENSGGOG00000041405.1|UniProtKB=A0A2I2YSF2 A0A2I2YSF2 PTHR13036:SF5 BETA1,4 MANNOSYLTRANSFERASE CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000036790.1|UniProtKB=A0A2I2YMR0 A0A2I2YMR0 PTHR28436:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM5 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM5 HOMOLOG primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000000061.3|UniProtKB=G3QCW0 G3QCW0 TIPIN PTHR13220:SF12 TIMELESS INTERACTING-RELATED TIMELESS-INTERACTING PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA-templated DNA replication#GO:2000104;negative regulation of cellular process#GO:0048523;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;regulation of DNA-templated DNA replication#GO:0090329;cellular response to stimulus#GO:0051716;regulation of DNA metabolic process#GO:0051052;DNA replication#GO:0006260;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;cellular response to stress#GO:0033554;regulation of DNA replication#GO:0006275;DNA-templated DNA replication#GO:0006261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000002637.3|UniProtKB=A1YFA5 A1YFA5 HOXB7 PTHR45659:SF11 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B7 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000006437.3|UniProtKB=G3QU94 G3QU94 PIGU PTHR13121:SF0 GPI TRANSAMIDASE COMPONENT PIG-U GPI-ANCHOR TRANSAMIDASE COMPONENT PIGU cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;caspase complex#GO:0008303;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endopeptidase complex#GO:1905369;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 GORGO|Ensembl=ENSGGOG00000043529.1|UniProtKB=G3RPZ9 G3RPZ9 C4B PTHR11412:SF86 MACROGLOBULIN / COMPLEMENT COMPLEMENT C4-A-RELATED chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000013661.3|UniProtKB=G3RCT5 G3RCT5 GPR15 PTHR24228:SF10 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G PROTEIN-COUPLED RECEPTOR 15 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;developmental process#GO:0032502;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000005001.3|UniProtKB=Q0MQI2 Q0MQI2 NDUFS8 PTHR10849:SF20 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 8, MITOCHONDRIAL oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824 mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000037325.1|UniProtKB=A0A2I2Y5W7 A0A2I2Y5W7 RNASE4 PTHR11437:SF53 RIBONUCLEASE RIBONUCLEASE 4 nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830;defense response#GO:0006952;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742 RNA metabolism protein#PC00031;endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000000773.3|UniProtKB=G3QER3 G3QER3 TMEM14A PTHR12668:SF11 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14A intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000015577.3|UniProtKB=G3RHR9 G3RHR9 ACP1 PTHR11717:SF35 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000026381.2|UniProtKB=G3SCY6 G3SCY6 PTHR23268:SF114 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 7-9 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000011402.3|UniProtKB=G3R6Z5 G3R6Z5 RTCB PTHR11118:SF1 RNA-SPLICING LIGASE RTCB HOMOLOG RNA-SPLICING LIGASE RTCB ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000013527.3|UniProtKB=G3RCG6 G3RCG6 DNAL4 PTHR11886:SF2 DYNEIN LIGHT CHAIN DYNEIN AXONEMAL LIGHT CHAIN 4 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 GORGO|Ensembl=ENSGGOG00000010471.3|UniProtKB=G3R4L0 G3R4L0 FKBP4 PTHR10516:SF25 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4 cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000001581.3|UniProtKB=G3SB23 G3SB23 VPS26C PTHR12233:SF2 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26C intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000037749.1|UniProtKB=A0A2I2YZA1 A0A2I2YZA1 SPATA45 PTHR35822:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 45 SPERMATOGENESIS-ASSOCIATED PROTEIN 45 GORGO|Ensembl=ENSGGOG00000011643.3|UniProtKB=A0A2I2Z5J5 A0A2I2Z5J5 SCYL3 PTHR12984:SF15 SCY1-RELATED S/T PROTEIN KINASE-LIKE PROTEIN-ASSOCIATING WITH THE CARBOXYL-TERMINAL DOMAIN OF EZRIN non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000039936.1|UniProtKB=A0A2I2YZP2 A0A2I2YZP2 PTHR11021:SF5 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F SM PROTEIN F nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000015329.3|UniProtKB=G3RH42 G3RH42 CAAP1 PTHR14740:SF3 CASPASE ACTIVITY AND APOPTOSIS INHIBITOR 1 CASPASE ACTIVITY AND APOPTOSIS INHIBITOR 1 GORGO|Ensembl=ENSGGOG00000001486.3|UniProtKB=A0A2I2ZF96 A0A2I2ZF96 ANKRD54 PTHR24197:SF51 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 54 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000005263.3|UniProtKB=G3QRA9 G3QRA9 FXYD5 PTHR14132:SF14 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 5 transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of monoatomic ion transmembrane transport#GO:0034765;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of transport#GO:0051050 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000009964.3|UniProtKB=A0A2I2YBT0 A0A2I2YBT0 GAREM1 PTHR14454:SF6 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;epidermal growth factor receptor signaling pathway#GO:0007173;biological regulation#GO:0065007 GORGO|Ensembl=ENSGGOG00000011816.3|UniProtKB=G3R821 G3R821 SPEM2 PTHR34834:SF2 SPERMATID MATURATION PROTEIN 1 SPEM FAMILY MEMBER 2 GORGO|Ensembl=ENSGGOG00000039464.1|UniProtKB=A0A2I2YQR3 A0A2I2YQR3 LOC129532266 PTHR19970:SF25 RIBOSOMAL PROTEIN L39E LARGE RIBOSOMAL SUBUNIT PROTEIN EL39 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000000957.3|UniProtKB=G3QF78 G3QF78 PTPN14 PTHR45706:SF6 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 14 hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;anatomical structure development#GO:0048856;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;circulatory system development#GO:0072359;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000025227.2|UniProtKB=G3S612 G3S612 CEP290 PTHR18879:SF22 CENTROSOMAL PROTEIN OF 290 KDA CENTROSOMAL PROTEIN OF 290 KDA multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;sensory system development#GO:0048880;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;renal system development#GO:0072001;kidney development#GO:0001822;cellular process#GO:0009987;cell projection assembly#GO:0030031;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection assembly#GO:0120031;sensory organ development#GO:0007423;developmental process#GO:0032502;cell projection organization#GO:0030030;visual system development#GO:0150063;cellular component organization#GO:0016043;cilium assembly#GO:0060271;ciliary transition zone assembly#GO:1905349;anatomical structure development#GO:0048856;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;eye development#GO:0001654;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;camera-type eye development#GO:0043010 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;centriolar satellite#GO:0034451 GORGO|Ensembl=ENSGGOG00000023799.2|UniProtKB=G3RVV8 G3RVV8 SERPINA7 PTHR11461:SF375 SERINE PROTEASE INHIBITOR, SERPIN THYROXINE-BINDING GLOBULIN enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 GORGO|Gene=OR1A1|UniProtKB=Q9TU92 Q9TU92 OR1A1 PTHR26453:SF589 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1A1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000002228.3|UniProtKB=G3QII6 G3QII6 CDKL3 PTHR24056:SF177 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000011995.3|UniProtKB=G3S6I2 G3S6I2 OXTR PTHR24241:SF89 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OXYTOCIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to hormone#GO:0009725;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;response to chemical#GO:0042221;regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;system process#GO:0003008;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system process#GO:0003013;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of biological quality#GO:0065008;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Oxytocin receptor mediated signaling pathway#P04391>Oxytocin Receptor#P04531 GORGO|Ensembl=ENSGGOG00000001570.3|UniProtKB=G3QGT6 G3QGT6 FAM186B PTHR33590:SF3 GLUTENIN, HIGH MOLECULAR WEIGHT SUBUNIT PW212-RELATED PROTEIN PROTEIN FAM186B GORGO|Ensembl=ENSGGOG00000016922.3|UniProtKB=A0A2I2YR37 A0A2I2YR37 MFF PTHR16501:SF20 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11 MITOCHONDRIAL FISSION FACTOR positive regulation of organelle organization#GO:0010638;localization#GO:0051179;positive regulation of cellular component organization#GO:0051130;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;protein localization to mitochondrion#GO:0070585;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;intracellular protein localization#GO:0008104;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;microbody#GO:0042579;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;peroxisome#GO:0005777;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000002360.3|UniProtKB=G3RXN2 G3RXN2 STAMBP PTHR12947:SF8 AMSH-LIKE PROTEASE STAM-BINDING PROTEIN peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824 late endosome to vacuole transport#GO:0045324;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of Ras protein signal transduction#GO:0046578;localization#GO:0051179;cellular localization#GO:0051641;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;endosome transport via multivesicular body sorting pathway#GO:0032509;negative regulation of response to stimulus#GO:0048585;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;regulation of small GTPase mediated signal transduction#GO:0051056;endosomal transport#GO:0016197;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523 cleavage furrow#GO:0032154;plasma membrane#GO:0005886;cell division site#GO:0032153;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 metalloprotease#PC00153;protease#PC00190 GORGO|Ensembl=ENSGGOG00000016860.3|UniProtKB=G3SI50 G3SI50 KRT38 PTHR23239:SF387 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA8 structural molecule activity#GO:0005198 organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 intermediate filament#PC00129 GORGO|Ensembl=ENSGGOG00000007880.3|UniProtKB=A0A2I2Z949 A0A2I2Z949 FBXW11 PTHR14604:SF6 WD40 REPEAT PF20 F-BOX AND WD REPEAT DOMAIN-CONTAINING 11-B enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 microtubule or microtubule-binding cytoskeletal protein#PC00157 Hedgehog signaling pathway#P00025>Slimb#P00683;Wnt signaling pathway#P00057>betaTrCP#P01454;Parkinson disease#P00049>hSel10#P01240 GORGO|Ensembl=ENSGGOG00000010427.3|UniProtKB=G3R4H0 G3R4H0 VSTM1 PTHR11738:SF180 MHC CLASS I NK CELL RECEPTOR V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;biological regulation#GO:0065007;signaling#GO:0023052;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000022822.2|UniProtKB=G3S2A8 G3S2A8 PTHR11524:SF28 60S RIBOSOMAL PROTEIN L7 RPL7 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000010270.3|UniProtKB=G3R433 G3R433 DEPDC4 PTHR16206:SF10 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 4 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015696.3|UniProtKB=A0A2I2Z3T3 A0A2I2Z3T3 PTHR11711:SF343 ADP RIBOSYLATION FACTOR-RELATED ADP RIBOSYLATION FACTOR 1 GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367 intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020 GORGO|Ensembl=ENSGGOG00000041471.1|UniProtKB=A0A2I2YA88 A0A2I2YA88 PRKG1 PTHR24353:SF68 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567;CCKR signaling map#P06959>cGK 1#P07149 GORGO|Ensembl=ENSGGOG00000004389.3|UniProtKB=G3QP20 G3QP20 GPR37 PTHR46216:SF3 PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER PROSAPOSIN RECEPTOR GPR37 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;G protein-coupled receptor signaling pathway#GO:0007186;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Parkinson disease#P00049>Pael-R#P01229 GORGO|Ensembl=ENSGGOG00000003617.3|UniProtKB=G3QM27 G3QM27 F8A1 PTHR16797:SF4 FACTOR VIII-ASSOCIATED GENE 1 40-KDA HUNTINGTIN-ASSOCIATED PROTEIN transport#GO:0006810;intracellular transport#GO:0046907;organelle localization#GO:0051640;vesicle cytoskeletal trafficking#GO:0099518;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000009037.3|UniProtKB=G3R0Z1 G3R0Z1 SYT5 PTHR10024:SF282 SYNAPTOTAGMIN SYNAPTOTAGMIN-5 protein binding#GO:0005515;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149 regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;positive regulation of vesicle fusion#GO:0031340;vesicle-mediated transport in synapse#GO:0099003;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of neurotransmitter transport#GO:0051588;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of synaptic vesicle exocytosis#GO:2000300;export from cell#GO:0140352;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular component organization#GO:0051128;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of exocytosis#GO:0017157;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916 membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane#GO:0005886;organelle membrane#GO:0031090;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;secretory vesicle#GO:0099503;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 GORGO|Ensembl=ENSGGOG00000001323.3|UniProtKB=G3QG53 G3QG53 CETN1 PTHR23064:SF32 TROPONIN CALTRACTIN ICL1D actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000037745.1|UniProtKB=A0A2I2ZSC0 A0A2I2ZSC0 PTHR19433:SF83 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 36_DELTA VARIABLE 7 response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000008195.3|UniProtKB=G3QYR9 G3QYR9 SFXN1 PTHR11153:SF8 SIDEROFLEXIN SIDEROFLEXIN-1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;cellular localization#GO:0051641;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;intracellular transport#GO:0046907;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000010552.3|UniProtKB=G3R4S7 G3R4S7 MRPL2 PTHR13691:SF73 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543 large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;cytosolic large ribosomal subunit#GO:0022625;organelle lumen#GO:0043233;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000012450.3|UniProtKB=A0A2I2ZC63 A0A2I2ZC63 EPB41L3 PTHR23280:SF20 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 3 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 GORGO|Ensembl=ENSGGOG00000016915.3|UniProtKB=A0A2I2ZKB4 A0A2I2ZKB4 ZFP57 PTHR24381:SF277 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 57 HOMOLOG sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000009268.3|UniProtKB=G3R1I3 G3R1I3 ZC3H12A PTHR12876:SF10 N4BP1-RELATED ENDORIBONUCLEASE ZC3H12A catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000010031.3|UniProtKB=G3R3G0 G3R3G0 KCNK6 PTHR11003:SF28 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 6 voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000004080.3|UniProtKB=G3QNA0 G3QNA0 MYOM3 PTHR13817:SF89 TITIN MYOMESIN-3 structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029 contractile muscle fiber#GO:0043292;A band#GO:0031672;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;M band#GO:0031430;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000043358.1|UniProtKB=A0A2I2ZRB3 A0A2I2ZRB3 FOXB2 PTHR11829:SF215 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN B2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000005832.3|UniProtKB=A0A2I2ZLC9 A0A2I2ZLC9 EIF4G3 PTHR23253:SF23 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 3 RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000010488.3|UniProtKB=G3R4L9 G3R4L9 CBLN4 PTHR22923:SF3 CEREBELLIN-RELATED CEREBELLIN-4 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000003677.3|UniProtKB=A0A2I2YV67 A0A2I2YV67 NUP58 PTHR13437:SF2 NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1 NUCLEOPORIN P58_P45 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;nuclear transport#GO:0051169;intracellular transport#GO:0046907;transport#GO:0006810;nucleocytoplasmic transport#GO:0006913 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle envelope#GO:0031967 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000013006.3|UniProtKB=G3RB50 G3RB50 LYAR PTHR13100:SF10 CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR CELL GROWTH-REGULATING NUCLEOLAR PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;rRNA processing#GO:0006364;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;RNA metabolic process#GO:0016070;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000013338.3|UniProtKB=G3RP49 G3RP49 IPP PTHR24412:SF35 KELCH PROTEIN ACTIN-BINDING PROTEIN IPP enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000037507.1|UniProtKB=A0A2I2Z168 A0A2I2Z168 PTHR32014:SF2 BCL-2-MODIFYING FACTOR BCL-2-MODIFYING FACTOR negative regulation of catabolic process#GO:0009895;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000002611.3|UniProtKB=G3QJH9 G3QJH9 DNAJC16 PTHR44303:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 biological regulation#GO:0065007;macroautophagy#GO:0016236;catabolic process#GO:0009056;autophagy#GO:0006914;regulation of cellular component size#GO:0032535;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;regulation of biological quality#GO:0065008;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000036472.1|UniProtKB=A0A2I2Z4M6 A0A2I2Z4M6 IGKV1-6 PTHR23267:SF502 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-6 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000027920.2|UniProtKB=G3SA27 G3SA27 CCIN PTHR24412:SF163 KELCH PROTEIN CALICIN ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000200.3|UniProtKB=A0A2I2ZS14 A0A2I2ZS14 APP PTHR23103:SF16 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID-BETA PRECURSOR PROTEIN protein binding#GO:0005515;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102;binding#GO:0005488 cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502 intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane raft#GO:0045121;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane microdomain#GO:0098857;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000043003.1|UniProtKB=A0A2I2ZX56 A0A2I2ZX56 PTHR26450:SF132 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR OLFR654 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000004258.3|UniProtKB=A0A2I2Z2P3 A0A2I2Z2P3 RPS5 PTHR11205:SF34 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;RNA binding#GO:0003723 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000011959.3|UniProtKB=G3R8I5 G3R8I5 DNAAF9 PTHR33664:SF1 RCG26366 DYNEIN AXONEMAL ASSEMBLY FACTOR 9 GORGO|Ensembl=ENSGGOG00000004896.3|UniProtKB=G3RVA2 G3RVA2 IKBKG PTHR31553:SF3 NF-KAPPA-B ESSENTIAL MODULATOR NF-KAPPA-B ESSENTIAL MODULATOR K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488;protein binding#GO:0005515 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000000302.3|UniProtKB=G3QDH9 G3QDH9 TM4SF20 PTHR14198:SF17 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 20 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000012279.3|UniProtKB=G3R9A2 G3R9A2 PTHR10671:SF42 EPITHELIAL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 202 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000026155.2|UniProtKB=G3SF95 G3SF95 LRRC10 PTHR16083:SF8 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 10 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 cell development#GO:0048468;cell differentiation#GO:0030154;circulatory system development#GO:0072359;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;muscle tissue development#GO:0060537;system development#GO:0048731;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;cardiac muscle cell differentiation#GO:0055007;heart development#GO:0007507;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cellular process#GO:0009987;striated muscle cell differentiation#GO:0051146;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;animal organ development#GO:0048513;cellular developmental process#GO:0048869;developmental process#GO:0032502;striated muscle tissue development#GO:0014706 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000027503.2|UniProtKB=A0A2I2ZUK0 A0A2I2ZUK0 PTHR45956:SF5 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN DOMAIN-CONTAINING PROTEIN regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of axonogenesis#GO:0050770 intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;neuron projection#GO:0043005;cell body#GO:0044297 GORGO|Ensembl=ENSGGOG00000036568.1|UniProtKB=A0A2I2YX65 A0A2I2YX65 PTHR15591:SF16 RUN AND SH3 DOMAIN CONTAINING FARNESYL PYROPHOSPHATE SYNTHASE organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000040354.1|UniProtKB=A0A2I2Z1U0 A0A2I2Z1U0 APLN PTHR15953:SF0 APELIN APELIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004443.3|UniProtKB=G3QP72 G3QP72 IL22RA1 PTHR20859:SF53 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;signaling#GO:0023052;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000016675.3|UniProtKB=G3RKK4 G3RKK4 MAMLD1 PTHR15275:SF0 CG1 PROTEIN/F18 MASTERMIND-LIKE DOMAIN-CONTAINING PROTEIN 1 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 GORGO|Ensembl=ENSGGOG00000041571.1|UniProtKB=A0A2I2YL41 A0A2I2YL41 MRPL30 PTHR15892:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000005574.4|UniProtKB=G3QS45 G3QS45 COL25A1 PTHR37456:SF3 SI:CH211-266K2.1 COLLAGEN ALPHA-1(XXV) CHAIN peptide binding#GO:0042277;binding#GO:0005488 GORGO|Ensembl=ENSGGOG00000042358.1|UniProtKB=A0A2I2ZX49 A0A2I2ZX49 PTHR23266:SF283 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 2-RELATED binding#GO:0005488;antigen binding#GO:0003823 leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000014258.3|UniProtKB=G3REC7 G3REC7 PAFAH2 PTHR10272:SF6 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE 2, CYTOPLASMIC catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000028384.2|UniProtKB=G3RZ79 G3RZ79 PTHR31102:SF5 FAMILY NOT NAMED SLC9B1-LIKE PROTEIN SLC9B1P1-RELATED transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 GORGO|Ensembl=ENSGGOG00000004121.3|UniProtKB=G3QND2 G3QND2 MFSD5 PTHR23516:SF1 SAM (S-ADENOSYL METHIONINE) TRANSPORTER SOLUTE CARRIER FAMILY 61 MEMBER 1 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000002499.3|UniProtKB=G3QJ77 G3QJ77 ATP1B1 PTHR11523:SF10 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1 ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;membrane#GO:0016020;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006517.3|UniProtKB=G3QUH4 G3QUH4 TAS2R13 PTHR11394:SF28 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 13 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000009528.3|UniProtKB=G3R265 G3R265 PTHR11537:SF171 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNF1 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459 action potential#GO:0001508;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000001024.3|UniProtKB=G3RRH9 G3RRH9 LRP4 PTHR46513:SF44 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 4 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000025553.2|UniProtKB=G3RV24 G3RV24 PTHR15566:SF12 POM121-LIKE SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000003600.3|UniProtKB=G3QM23 G3QM23 F8 PTHR24543:SF320 MULTICOPPER OXIDASE-RELATED COAGULATION FACTOR VIII cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;coagulation#GO:0050817;response to stress#GO:0006950;response to wounding#GO:0009611;biological regulation#GO:0065007;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;blood coagulation#GO:0007596;macromolecule metabolic process#GO:0043170;hemostasis#GO:0007599;primary metabolic process#GO:0044238;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;blood coagulation, fibrin clot formation#GO:0072378;regulation of biological quality#GO:0065008;wound healing#GO:0042060;protein metabolic process#GO:0019538;protein activation cascade#GO:0072376 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176 Blood coagulation#P00011>FVIII#P00405;Blood coagulation#P00011>FVIIIa#P00446 GORGO|Ensembl=ENSGGOG00000003219.3|UniProtKB=A0A2I2YTL6 A0A2I2YTL6 MAP7D1 PTHR15073:SF2 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 1 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000010422.3|UniProtKB=G3R4G4 G3R4G4 NIPSNAP3A PTHR21017:SF23 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 3A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 mitophagy#GO:0000423;process utilizing autophagic mechanism#GO:0061919;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;catabolic process#GO:0009056;macroautophagy#GO:0016236;cellular process#GO:0009987;autophagy#GO:0006914 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000027002.2|UniProtKB=G3SD95 G3SD95 THBS4 PTHR10199:SF92 THROMBOSPONDIN THROMBOSPONDIN-4 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;response to stress#GO:0006950;response to stimulus#GO:0050896 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 GORGO|Ensembl=ENSGGOG00000005482.3|UniProtKB=G3QRW1 G3QRW1 PARD3 PTHR16484:SF10 PARTITIONING DEFECTIVE 3 RELATED PARTITIONING DEFECTIVE 3 HOMOLOG small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167 cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;localization#GO:0051179;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;microtubule cytoskeleton organization#GO:0000226 apical part of cell#GO:0045177;apical junction complex#GO:0043296;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054;cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;cell-cell junction#GO:0005911;apical plasma membrane#GO:0016324;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 GORGO|Ensembl=ENSGGOG00000040827.1|UniProtKB=A0A2I2ZV98 A0A2I2ZV98 PDSS2 PTHR12001:SF55 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2 prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;isoprenoid metabolic process#GO:0006720 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000037788.1|UniProtKB=A0A2I2ZV86 A0A2I2ZV86 PTHR37553:SF10 DUF4705 DOMAIN-CONTAINING PROTEIN DUF4705 DOMAIN-CONTAINING PROTEIN GORGO|Ensembl=ENSGGOG00000010559.3|UniProtKB=G3R4T7 G3R4T7 PSMB4 PTHR11599:SF5 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-4 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000010062.3|UniProtKB=G3R3I9 G3R3I9 GNA13 PTHR10218:SF85 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-13 hydrolase activity#GO:0016787;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;side of membrane#GO:0098552;cell projection membrane#GO:0031253;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;brush border membrane#GO:0031526;plasma membrane region#GO:0098590;cell periphery#GO:0071944;brush border#GO:0005903;membrane#GO:0016020;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;apical part of cell#GO:0045177 G-protein#PC00020;heterotrimeric G-protein#PC00117 GORGO|Ensembl=ENSGGOG00000038447.1|UniProtKB=A0A2I2Y7K5 A0A2I2Y7K5 PTHR12107:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-4 SUBUNIT transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;channel regulator activity#GO:0016247 regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;localization#GO:0051179;nervous system process#GO:0050877;regulation of signaling#GO:0023051;localization within membrane#GO:0051668;positive regulation of synaptic transmission#GO:0050806;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072 transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 GORGO|Ensembl=ENSGGOG00000011636.3|UniProtKB=G3R7L3 G3R7L3 DUS1L PTHR11082:SF5 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000009041.3|UniProtKB=G3RMB3 G3RMB3 TPH1 PTHR11473:SF23 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 1 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 serotonin metabolic process#GO:0042428;metabolic process#GO:0008152;serotonin biosynthetic process#GO:0042427;biosynthetic process#GO:0009058;phenol-containing compound biosynthetic process#GO:0046189;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;phenol-containing compound metabolic process#GO:0018958 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 GORGO|Ensembl=ENSGGOG00000014848.3|UniProtKB=G3RFV5 G3RFV5 DBX1 PTHR24331:SF6 DBX HOMEOBOX PROTEIN DBX1 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000000522.3|UniProtKB=G3QE29 G3QE29 LOC101127173 PTHR24300:SF438 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C8 binding#GO:0005488;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;arachidonate metabolic process#GO:0019369;cellular response to stimulus#GO:0051716;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;olefinic compound metabolic process#GO:0120254;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular response to xenobiotic stimulus#GO:0071466;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000010058.3|UniProtKB=G3R3J1 G3R3J1 SASH1 PTHR12301:SF3 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM AND SH3 DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of signal transduction#GO:0009967;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 GORGO|Ensembl=ENSGGOG00000013833.3|UniProtKB=G3RD93 G3RD93 PLA2G2C PTHR11716:SF5 PHOSPHOLIPASE A2 FAMILY MEMBER INACTIVE GROUP IIC SECRETORY PHOSPHOLIPASE A2-RELATED carboxylic ester hydrolase activity#GO:0052689;ion binding#GO:0043167;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;lipase activity#GO:0016298;cation binding#GO:0043169;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;calcium ion binding#GO:0005509;binding#GO:0005488;lipid binding#GO:0008289;protein binding#GO:0005515;metal ion binding#GO:0046872;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623 glycerolipid metabolic process#GO:0046486;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;phosphatidylglycerol metabolic process#GO:0046471;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 phospholipase#PC00186 GORGO|Ensembl=ENSGGOG00000010117.3|UniProtKB=A0A2I2ZIA0 A0A2I2ZIA0 ZC3H12C PTHR12876:SF36 N4BP1-RELATED RIBONUCLEASE ZC3H12C-RELATED RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA binding#GO:0003723;nuclease activity#GO:0004518;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000024907.2|UniProtKB=G3S5J3 G3S5J3 LOC101133227 PTHR10288:SF93 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 2 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA stability#GO:0043487;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;mRNA stabilization#GO:0048255 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000017146.3|UniProtKB=G3RLS2 G3RLS2 C3H4orf19 PTHR16106:SF3 CHROMOSOME 4 OPEN READING FRAME 19 PDCD10 AND GCKIII KINASES-ASSOCIATED PROTEIN 1 GORGO|Ensembl=ENSGGOG00000036398.1|UniProtKB=A0A2I2ZCI6 A0A2I2ZCI6 PTHR23268:SF101 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 9 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000028363.2|UniProtKB=G3SKC0 G3SKC0 S1PR1 PTHR22750:SF16 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;circulatory system development#GO:0072359;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000014416.3|UniProtKB=A0A2I2Z0S5 A0A2I2Z0S5 CENPL PTHR31740:SF2 CENTROMERE PROTEIN L CENTROMERE PROTEIN L GORGO|Ensembl=ENSGGOG00000028073.2|UniProtKB=A0A2I2ZXG1 A0A2I2ZXG1 UBE2L3 PTHR24068:SF67 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 L3 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein K11-linked ubiquitination#GO:0070979;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>UbcH7#P01224 GORGO|Ensembl=ENSGGOG00000040332.1|UniProtKB=A0A2I2ZM23 A0A2I2ZM23 SLC2A13 PTHR48020:SF55 PROTON MYO-INOSITOL COTRANSPORTER PROTON MYO-INOSITOL COTRANSPORTER solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000014766.4|UniProtKB=G3RFQ2 G3RFQ2 MYO9A PTHR46184:SF3 UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UNCONVENTIONAL MYOSIN-IXA protein-containing complex binding#GO:0044877;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;actin filament binding#GO:0051015;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824 cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;developmental process#GO:0032502;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;establishment of cell polarity#GO:0030010;cell differentiation#GO:0030154;establishment or maintenance of bipolar cell polarity#GO:0061245;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of cell polarity#GO:0007163;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;neuron projection#GO:0043005;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;actin filament#GO:0005884;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;axon#GO:0030424;growth cone#GO:0030426;axonal growth cone#GO:0044295 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000010495.3|UniProtKB=A0A2I2ZQL9 A0A2I2ZQL9 NPRL3 PTHR13153:SF5 CGTHBA PROTEIN -14 GENE PROTEIN GATOR1 COMPLEX PROTEIN NPRL3 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;negative regulation of TORC1 signaling#GO:1904262;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794 Seh1-associated complex#GO:0035859;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000024036.2|UniProtKB=G3RY47 G3RY47 PTHR12297:SF13 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN-CONTAINING PROTEIN cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;cellular component assembly#GO:0022607;negative regulation of apoptotic process#GO:0043066;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of cellular process#GO:0050794;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000598.3|UniProtKB=G3RS99 G3RS99 ISOC2 PTHR14119:SF19 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000005922.3|UniProtKB=G3QT03 G3QT03 WDR19 PTHR14920:SF2 OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN WD REPEAT-CONTAINING PROTEIN 19 cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;cilium assembly#GO:0060271;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111 cilium#GO:0005929;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227;intraciliary transport particle A#GO:0030991;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000006669.3|UniProtKB=G3QUW6 G3QUW6 OCIAD1 PTHR13336:SF4 OVARIAN CARCINOMA IMMUNOREACTIVE ANTIGEN OCIA DOMAIN-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000000796.3|UniProtKB=G3QET4 G3QET4 SRI PTHR46735:SF7 CALPAIN, SMALL SUBUNIT 1 A-RELATED SORCIN calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 GORGO|Ensembl=ENSGGOG00000000099.3|UniProtKB=G3QCZ6 G3QCZ6 RPRML PTHR28649:SF3 PROTEIN REPRIMO-RELATED REPRIMO-LIKE PROTEIN GORGO|Ensembl=ENSGGOG00000009359.3|UniProtKB=G3R1R5 G3R1R5 ELOVL4 PTHR11157:SF126 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 4 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;acyltransferase#PC00042 GORGO|Ensembl=ENSGGOG00000009228.3|UniProtKB=A0A2I2ZI59 A0A2I2ZI59 PTHR16502:SF1 KERATINOCYTE-ASSOCIATED TRANSMEMBRANE PROTEIN 2 KERATINOCYTE-ASSOCIATED TRANSMEMBRANE PROTEIN 2 GORGO|Ensembl=ENSGGOG00000006358.3|UniProtKB=G3QU34 G3QU34 SLC13A1 PTHR10283:SF65 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 1 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 metal ion transport#GO:0030001;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000011901.3|UniProtKB=G3S1W6 G3S1W6 LOC101129100 PTHR24092:SF46 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE ID intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326 organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;lipid transport#GO:0006869;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 primary active transporter#PC00068;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000004221.3|UniProtKB=G3QNM0 G3QNM0 SLC46A2 PTHR23507:SF3 ZGC:174356 SOLUTE CARRIER FAMILY 46 MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016686.3|UniProtKB=G3RKL0 G3RKL0 SDF2 PTHR46809:SF3 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN STROMAL CELL-DERIVED FACTOR 2 GORGO|Ensembl=ENSGGOG00000003289.3|UniProtKB=G3QL83 G3QL83 NAT9 PTHR13256:SF16 N-ACETYLTRANSFERASE 9 ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9 protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acyltransferase activity#GO:0140186;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080 regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;positive regulation of organelle organization#GO:0010638;regulation of microtubule polymerization#GO:0031113;regulation of microtubule-based process#GO:0032886;positive regulation of cellular component organization#GO:0051130;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of microtubule polymerization or depolymerization#GO:0031110 GORGO|Ensembl=ENSGGOG00000002669.3|UniProtKB=G3QJN0 G3QJN0 NTMT1 PTHR12753:SF1 AD-003 - RELATED N-TERMINAL XAA-PRO-LYS N-METHYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 methyltransferase#PC00155;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000000414.3|UniProtKB=G3QDT1 G3QDT1 KPNA7 PTHR23316:SF11 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-8 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000009035.3|UniProtKB=G3R0Y7 G3R0Y7 ZYG11A PTHR12904:SF20 FAMILY NOT NAMED PROTEIN ZYG-11 HOMOLOG A intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000013416.3|UniProtKB=G3RC67 G3RC67 CEP57 PTHR19336:SF11 UNCHARACTERIZED DUF1167 CENTROSOMAL PROTEIN OF 57 KDA molecular adaptor activity#GO:0060090;cytoskeletal adaptor activity#GO:0008093;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515 organelle organization#GO:0006996;attachment of spindle microtubules to kinetochore#GO:0008608;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 GORGO|Ensembl=ENSGGOG00000010954.3|UniProtKB=G3R5U3 G3R5U3 CIB2 PTHR45791:SF5 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 2 cation binding#GO:0043169;magnesium ion binding#GO:0000287;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;calcium ion homeostasis#GO:0055074;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878 intracellular organelle#GO:0043229;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;stereocilium#GO:0032420;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;neuron projection#GO:0043005;cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 Ras Pathway#P04393>Rac#P04559 GORGO|Ensembl=ENSGGOG00000043343.1|UniProtKB=A0A2I2ZZ02 A0A2I2ZZ02 LOC109023896 PTHR12884:SF18 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000008605.3|UniProtKB=G3QZU3 G3QZU3 SIX2 PTHR10390:SF77 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;renal system development#GO:0072001;kidney development#GO:0001822;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000016094.3|UniProtKB=G3RJ25 G3RJ25 LOC101144247 PTHR46131:SF5 SD08549P SOLUTE CARRIER FAMILY 25 MEMBER 53 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;purine nucleotide transmembrane transporter activity#GO:0015216;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 GORGO|Ensembl=ENSGGOG00000027753.2|UniProtKB=G3S7W7 G3S7W7 CLDN8 PTHR12002:SF24 CLAUDIN CLAUDIN-8 paracellular tight junction channel activity#GO:0160187;transporter activity#GO:0005215 cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;transport#GO:0006810;paracellular transport#GO:0160184;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell junction organization#GO:0034330 tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 tight junction#PC00214;cell junction protein#PC00070 GORGO|Ensembl=ENSGGOG00000013201.4|UniProtKB=G3RBL9 G3RBL9 PSMA6 PTHR11599:SF247 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-6 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000025722.2|UniProtKB=G3SE61 G3SE61 LOC101150855 PTHR11758:SF53 40S RIBOSOMAL PROTEIN S15A 40S RIBOSOMAL PROTEIN S15A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000026061.2|UniProtKB=A0A2I2ZDD1 A0A2I2ZDD1 UBE2C PTHR24068:SF360 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 C transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of mitotic metaphase/anaphase transition#GO:0030071;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;regulation of cell cycle phase transition#GO:1901987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;regulation of chromosome segregation#GO:0051983;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000038961.1|UniProtKB=A0A2I2Z3I8 A0A2I2Z3I8 RRAS PTHR24070:SF245 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN R-RAS ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;establishment or maintenance of cell polarity#GO:0007163;Ras protein signal transduction#GO:0007265 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 Integrin signalling pathway#P00034>Ras#P00916;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291 GORGO|Ensembl=ENSGGOG00000009383.3|UniProtKB=G3R1T5 G3R1T5 C18H16orf95 PTHR14693:SF0 RIKEN CDNA 1700018B08 RIKEN CDNA 1700018B08 GENE GORGO|Ensembl=ENSGGOG00000043317.1|UniProtKB=A0A2I2YUN6 A0A2I2YUN6 PTHR10722:SF18 60S RIBOSOMAL PROTEIN L19 RIBOSOMAL PROTEIN L19 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000009206.3|UniProtKB=G3R1D5 G3R1D5 CD70 PTHR15152:SF0 CD70 ANTIGEN CD70 ANTIGEN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;adaptive immune response#GO:0002250;cell surface receptor signaling pathway#GO:0007166;leukocyte activation#GO:0045321;T cell activation#GO:0042110;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;immune system process#GO:0002376;cell activation#GO:0001775;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000007268.3|UniProtKB=G3S6W6 G3S6W6 THRB PTHR24082:SF210 NUCLEAR HORMONE RECEPTOR THYROID HORMONE RECEPTOR BETA sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;negative regulation of transcription by RNA polymerase II#GO:0000122;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;intracellular receptor signaling pathway#GO:0030522 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 GORGO|Ensembl=ENSGGOG00000023048.2|UniProtKB=G3S2S2 G3S2S2 ZNF879 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022415.2|UniProtKB=A0A2I2ZXG3 A0A2I2ZXG3 LOC101128260 PTHR14614:SF174 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN SUBFAMILY NOT NAMED catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000013603.3|UniProtKB=G3RCN8 G3RCN8 LOC115930105 PTHR23226:SF234 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 716 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000036174.1|UniProtKB=A0A2I2ZPD3 A0A2I2ZPD3 PTHR11849:SF195 ETS GA-BINDING PROTEIN ALPHA CHAIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 GORGO|Ensembl=ENSGGOG00000006738.3|UniProtKB=G3RZN3 G3RZN3 ATP1A1 PTHR43294:SF9 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;sodium ion transmembrane transporter activity#GO:0015081;primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 import across plasma membrane#GO:0098739;export from cell#GO:0140352;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;monoatomic cation transport#GO:0006812;localization#GO:0051179;potassium ion homeostasis#GO:0055075;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080 transporter complex#GO:1990351;sarcolemma#GO:0042383;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000002625.3|UniProtKB=G3QJI9 G3QJI9 SPSB2 PTHR12245:SF2 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cytosol#GO:0005829;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Gene=CMAH|UniProtKB=Q8MJC8 Q8MJC8 CMAH PTHR46522:SF1 CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE INACTIVE CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;nucleoside phosphate metabolic process#GO:0006753 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydroxylase#PC00122;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000028561.2|UniProtKB=G3SBT7 G3SBT7 PTHR24381:SF5 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 749 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007098.3|UniProtKB=G3SC08 G3SC08 ACAD10 PTHR48083:SF35 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE FAMILY MEMBER 10 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 GORGO|Ensembl=ENSGGOG00000024976.2|UniProtKB=G3SAW3 G3SAW3 EEF1AKMT2 PTHR12843:SF5 PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10 EEF1A LYSINE METHYLTRANSFERASE 2 protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015289.3|UniProtKB=G3RH02 G3RH02 AIDA PTHR28654:SF1 AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN regulation of protein metabolic process#GO:0051246;determination of bilateral symmetry#GO:0009855;negative regulation of signal transduction#GO:0009968;regulation of MAPK cascade#GO:0043408;regulation of JNK cascade#GO:0046328;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;specification of symmetry#GO:0009799;regulation of protein modification process#GO:0031399;negative regulation of MAPK cascade#GO:0043409;dorsal/ventral pattern formation#GO:0009953;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;anatomical structure development#GO:0048856 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001803.3|UniProtKB=G3QHE7 G3QHE7 PRR4 PTHR23203:SF9 PROLINE-RICH PROTEIN PROLINE-RICH PROTEIN 4 antimicrobial response protein#PC00051 GORGO|Ensembl=ENSGGOG00000002376.3|UniProtKB=G3RUK9 G3RUK9 WDR97 PTHR45532:SF1 WD REPEAT-CONTAINING PROTEIN 97 WD REPEAT-CONTAINING PROTEIN 97 GORGO|Ensembl=ENSGGOG00000014201.3|UniProtKB=A0A2I2ZXS8 A0A2I2ZXS8 COPG1 PTHR10261:SF3 COATOMER SUBUNIT GAMMA COATOMER SUBUNIT GAMMA-1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810 intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;vesicle membrane#GO:0012506;membrane#GO:0016020;COPI-coated vesicle#GO:0030137;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000007321.3|UniProtKB=G3QWK2 G3QWK2 LRRC52 PTHR24366:SF61 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 52 immunoglobulin superfamily cell adhesion molecule#PC00125 GORGO|Ensembl=ENSGGOG00000015703.3|UniProtKB=G3S6I0 G3S6I0 MRPL16 PTHR12220:SF13 50S/60S RIBOSOMAL PROTEIN L16 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M RNA binding#GO:0003723;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005 GORGO|Ensembl=ENSGGOG00000014023.4|UniProtKB=A0A2I2YS93 A0A2I2YS93 TFE3 PTHR45776:SF3 MIP04163P TRANSCRIPTION FACTOR E3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000003142.3|UniProtKB=G3QKV4 G3QKV4 SPRTN PTHR21220:SF0 DNA-DEPENDENT METALLOPROTEASE SPRTN DNA-DEPENDENT METALLOPROTEASE SPRTN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA repair#GO:0006281;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA synthesis involved in DNA replication#GO:0090592;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000007285.3|UniProtKB=G3QWH3 G3QWH3 PTHR42693:SF11 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE A catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000003936.2|UniProtKB=G3QMW1 G3QMW1 DNAJB7 PTHR43948:SF4 DNAJ HOMOLOG SUBFAMILY B DNAJ HOMOLOG SUBFAMILY B MEMBER 7 protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000014352.3|UniProtKB=G3REK9 G3REK9 PTHR21845:SF2 TRANSMEMBRANE ANCHOR PROTEIN 1 MATRIX-REMODELING-ASSOCIATED PROTEIN 7 GORGO|Ensembl=ENSGGOG00000016895.3|UniProtKB=G3RTZ5 G3RTZ5 AP3S1 PTHR11753:SF12 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-3 COMPLEX SUBUNIT SIGMA-1 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000015500.3|UniProtKB=G3RHK3 G3RHK3 HNRNPK PTHR10288:SF331 KH DOMAIN CONTAINING RNA BINDING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000023106.2|UniProtKB=G3SHL5 G3SHL5 HAVCR2 PTHR15498:SF73 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING TIM HEPATITIS A VIRUS CELLULAR RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;intracellular receptor signaling pathway#GO:0030522;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of response to biotic stimulus#GO:0002833;regulation of gene expression#GO:0010468;pattern recognition receptor signaling pathway#GO:0002221;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;activation of innate immune response#GO:0002218;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of innate immune response#GO:0045089;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;organelle#GO:0043226;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000011213.3|UniProtKB=A0A2I2YTS7 A0A2I2YTS7 NOP14 PTHR23183:SF0 NOP14 NUCLEOLAR PROTEIN 14 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274 intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004858.3|UniProtKB=G3QQ95 G3QQ95 BANF2 PTHR47507:SF4 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR-LIKE PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000014170.3|UniProtKB=G3SHB2 G3SHB2 ZNF569 PTHR24404:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 835 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000013471.3|UniProtKB=G3RCB4 G3RCB4 STARD3NL PTHR46121:SF1 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STARD3 N-TERMINAL-LIKE PROTEIN sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094;steroid binding#GO:0005496;lipid binding#GO:0008289;cholesterol binding#GO:0015485;alcohol binding#GO:0043178 transport#GO:0006810;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;sterol transport#GO:0015918;establishment of localization#GO:0051234;localization#GO:0051179;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle membrane contact site#GO:0044232;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 GORGO|Ensembl=ENSGGOG00000016142.3|UniProtKB=G3RJ73 G3RJ73 ADAMTSL4 PTHR13723:SF144 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 4 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000001256.3|UniProtKB=A0A2I2ZIG7 A0A2I2ZIG7 GPR107 PTHR21229:SF12 LUNG SEVEN TRANSMEMBRANE RECEPTOR PROTEIN GPR107 clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898 clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000026680.2|UniProtKB=A0A2I2YPP3 A0A2I2YPP3 SYT14 PTHR46129:SF3 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN-14 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000000623.3|UniProtKB=A0A2I2Z6R7 A0A2I2Z6R7 HUS1 PTHR12900:SF4 MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 CHECKPOINT PROTEIN HUS1 negative regulation of cell cycle G2/M phase transition#GO:1902750;cellular component organization or biogenesis#GO:0071840;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;negative regulation of mitotic cell cycle phase transition#GO:1901991;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;telomere organization#GO:0032200;regulation of G2/M transition of mitotic cell cycle#GO:0010389;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;DNA replication checkpoint signaling#GO:0000076;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786;DNA recombination#GO:0006310;metabolic process#GO:0008152;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;response to stress#GO:0006950;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;signaling#GO:0023052;mitotic DNA replication checkpoint signaling#GO:0033314;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;telomere maintenance#GO:0000723;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;recombinational repair#GO:0000725;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000028352.2|UniProtKB=G3SJ97 G3SJ97 PLET1 PTHR22527:SF2 PLACENTA-EXPRESSED TRANSCRIPT 1 PROTEIN PLACENTA-EXPRESSED TRANSCRIPT 1 PROTEIN regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cell motility#GO:2000145;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;epithelium development#GO:0060429;negative regulation of cell adhesion#GO:0007162;tissue development#GO:0009888;regulation of cell adhesion#GO:0030155;cell migration#GO:0016477;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to wounding#GO:0009611;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of locomotion#GO:0040017;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;developmental process#GO:0032502;response to stimulus#GO:0050896;negative regulation of biological process#GO:0048519;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cell-matrix adhesion#GO:0001952;wound healing#GO:0042060;animal gross anatomical part developmental process#GO:0160108;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;morphogenesis of an epithelium#GO:0002009 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944 GORGO|Ensembl=ENSGGOG00000003014.3|UniProtKB=G3QKJ1 G3QKJ1 TRAK2 PTHR15751:SF13 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN 2 myosin binding#GO:0017022;binding#GO:0005488;signaling receptor binding#GO:0005102;GABA receptor binding#GO:0050811;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;vesicle localization#GO:0051648;neurogenesis#GO:0022008;mitochondrion localization#GO:0051646;vesicle cytoskeletal trafficking#GO:0099518;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;microtubule-based movement#GO:0007018;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;organelle localization#GO:0051640;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;establishment of organelle localization#GO:0051656;protein targeting#GO:0006605;cell differentiation#GO:0030154;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;animal gross anatomical part developmental process#GO:0160108 dendritic tree#GO:0097447;intracellular organelle#GO:0043229;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;mitochondrion#GO:0005739;intracellular vesicle#GO:0097708;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000007407.3|UniProtKB=G3QWT5 G3QWT5 ADD1 PTHR10672:SF4 ADDUCIN ALPHA-ADDUCIN cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;regulation of cell development#GO:0060284;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of developmental process#GO:0050793;regulation of actin filament depolymerization#GO:0030834;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of epithelial cell differentiation#GO:0030856;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cell differentiation#GO:0045597;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008 postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;cytoskeleton#GO:0005856;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572 non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000005580.3|UniProtKB=G3QS46 G3QS46 MYBPC2 PTHR13817:SF17 TITIN MYOSIN-BINDING PROTEIN C, FAST-TYPE structural molecule activity#GO:0005198 supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular organelle#GO:0043229;M band#GO:0031430;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;A band#GO:0031672 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000016057.3|UniProtKB=G3SIQ5 G3SIQ5 PIANP PTHR32023:SF2 PILR ALPHA-ASSOCIATED NEURAL PROTEIN PILR ALPHA-ASSOCIATED NEURAL PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000026212.2|UniProtKB=G3RPI9 G3RPI9 NPPC PTHR12167:SF2 C-TYPE NATRIURETIC PEPTIDE C-TYPE NATRIURETIC PEPTIDE signaling receptor binding#GO:0005102;binding#GO:0005488;hormone receptor binding#GO:0051427;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>CNP#G06905;Gonadotropin-releasing hormone receptor pathway#P06664>CNP#P06824;Gonadotropin-releasing hormone receptor pathway#P06664>CNP#G06690 GORGO|Ensembl=ENSGGOG00000015709.3|UniProtKB=G3RI37 G3RI37 MRPL55 PTHR34095:SF1 39S RIBOSOMAL PROTEIN L55, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML55 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000014964.3|UniProtKB=G3RG66 G3RG66 GGT7 PTHR11686:SF54 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 7 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;sulfur compound catabolic process#GO:0044273;catabolic process#GO:0009056 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000027059.2|UniProtKB=A0A2I2YB03 A0A2I2YB03 LOC101154513 PTHR13044:SF32 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 BZIP DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000038762.1|UniProtKB=A0A2I2ZUN0 A0A2I2ZUN0 PTHR12595:SF19 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;nucleobase-containing compound kinase activity#GO:0019205;ATP binding#GO:0005524;binding#GO:0005488;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotide binding#GO:0000166;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000011040.3|UniProtKB=G3RRS8 G3RRS8 PIK3C2A PTHR10048:SF28 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT ALPHA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;transferase activity#GO:0016740;catalytic activity#GO:0003824 phosphatidylinositol phosphate biosynthetic process#GO:0046854;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;cell motility#GO:0048870;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;biosynthetic process#GO:0009058;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137 FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;Integrin signalling pathway#P00034>PI3K#P00936;Axon guidance mediated by netrin#P00009>PI3K#P00363;VEGF signaling pathway#P00056>PI3K#P01413;Angiogenesis#P00005>PI3K#P00236;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;EGF receptor signaling pathway#P00018>PI3K#P00557 GORGO|Ensembl=ENSGGOG00000010321.3|UniProtKB=G3R477 G3R477 OR13A1 PTHR26452:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13A1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000010159.3|UniProtKB=G3R3T4 G3R3T4 CDK2AP2 PTHR22607:SF4 DELETED IN ORAL CANCER 1/CDK2-ASSOCIATED PROTEIN 1 CYCLIN-DEPENDENT KINASE 2-ASSOCIATED PROTEIN 2 regulation of microtubule-based process#GO:0032886;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle#GO:0007346;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 kinase modulator#PC00140;kinase inhibitor#PC00139 GORGO|Ensembl=ENSGGOG00000014509.3|UniProtKB=G3REZ6 G3REZ6 P2RY13 PTHR24233:SF10 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 13 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000000713.3|UniProtKB=G3S849 G3S849 PTHR23211:SF0 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN TGN38 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN 2 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000013175.3|UniProtKB=G3RBJ6 G3RBJ6 PTHR31711:SF1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000021934.2|UniProtKB=A0A2I2Z630 A0A2I2Z630 CCDC32 PTHR31800:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 GORGO|Ensembl=ENSGGOG00000005463.3|UniProtKB=G3QRU0 G3QRU0 KAT2A PTHR45750:SF1 GH11602P HISTONE ACETYLTRANSFERASE KAT2A protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000027185.2|UniProtKB=G3SIK4 G3SIK4 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E10-RELATED GORGO|Ensembl=ENSGGOG00000012874.3|UniProtKB=G3RAT0 G3RAT0 STX17 PTHR19957:SF139 SYNTAXIN SYNTAXIN-17 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;macromolecule localization#GO:0033036;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;vesicle fusion#GO:0006906;cellular component organization#GO:0016043 cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;autophagosome#GO:0005776 SNARE protein#PC00034 GORGO|Ensembl=ENSGGOG00000008635.3|UniProtKB=A0A2I2ZYW5 A0A2I2ZYW5 ELAVL3 PTHR10352:SF15 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 3 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 GORGO|Ensembl=ENSGGOG00000013274.3|UniProtKB=G3RBT2 G3RBT2 TUBA3E PTHR11588:SF113 TUBULIN TUBULIN ALPHA-3D CHAIN ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 cytoskeletal protein#PC00085;tubulin#PC00228 GORGO|Ensembl=ENSGGOG00000008821.3|UniProtKB=G3RRX0 G3RRX0 AGK PTHR12358:SF86 SPHINGOSINE KINASE ACYLGLYCEROL KINASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 sphingoid biosynthetic process#GO:0046520;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000007279.3|UniProtKB=G3QWH0 G3QWH0 POLR3C PTHR12949:SF0 RNA POLYMERASE III DNA DIRECTED -RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-directed RNA polymerase#PC00019 GORGO|Ensembl=ENSGGOG00000000550.3|UniProtKB=A0A2I2YYQ3 A0A2I2YYQ3 GALNT2 PTHR11675:SF49 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000043347.1|UniProtKB=A0A2I2Z726 A0A2I2Z726 PTHR43503:SF10 MCG48959-RELATED PEROXIREDOXIN-6 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 peroxidase#PC00180;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007073.3|UniProtKB=G3QVY5 G3QVY5 PIP4K2B PTHR23086:SF22 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 BETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transferase#PC00220;kinase#PC00137 GORGO|Ensembl=ENSGGOG00000003085.3|UniProtKB=G3QKQ5 G3QKQ5 GFM1 PTHR43636:SF2 ELONGATION FACTOR G, MITOCHONDRIAL ELONGATION FACTOR G, MITOCHONDRIAL translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000007148.3|UniProtKB=G3QW44 G3QW44 RMND1 PTHR16255:SF1 REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG positive regulation of protein metabolic process#GO:0051247;positive regulation of translation#GO:0045727;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604 GORGO|Ensembl=ENSGGOG00000025646.2|UniProtKB=G3SK17 G3SK17 LOC109026848 PTHR16771:SF18 26 PROTEASOME COMPLEX SUBUNIT DSS1 26S PROTEASOME COMPLEX SUBUNIT SEM1 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;peptidase complex#GO:1905368;protein-containing complex#GO:0032991 protease#PC00190;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000026067.2|UniProtKB=A0A2I2YL62 A0A2I2YL62 CDCA5 PTHR31092:SF2 SORORIN SORORIN cellular response to stress#GO:0033554;sister chromatid cohesion#GO:0007062;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;chromosome organization#GO:0051276;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;mitotic sister chromatid cohesion#GO:0007064;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000016039.3|UniProtKB=A0A2I2YKF9 A0A2I2YKF9 LITAF PTHR23292:SF2 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR metal ion binding#GO:0046872;cation binding#GO:0043169;zinc ion binding#GO:0008270;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;nucleus#GO:0005634;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic side of membrane#GO:0098562;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000010513.3|UniProtKB=G3R4P5 G3R4P5 PEX10 PTHR23350:SF0 PEROXISOME ASSEMBLY PROTEIN 10 PEROXISOME BIOGENESIS FACTOR 10 intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;peroxisome organization#GO:0007031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein transport#GO:0015031;peroxisomal transport#GO:0043574;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000036795.1|UniProtKB=A0A2I2Z7S1 A0A2I2Z7S1 PTHR13160:SF14 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000028500.2|UniProtKB=G3S0C3 G3S0C3 LOC101127756 PTHR13976:SF31 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA-BINDING PROTEIN 12 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 GORGO|Ensembl=ENSGGOG00000016032.3|UniProtKB=G3SI18 G3SI18 LOC101145215 PTHR24379:SF132 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 45 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000006238.3|UniProtKB=G3QTS0 G3QTS0 EME2 PTHR21077:SF6 EME1 PROTEIN STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT EME2 regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;organelle organization#GO:0006996;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;DNA-templated DNA replication#GO:0006261;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;replication fork processing#GO:0031297;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;resolution of meiotic recombination intermediates#GO:0000712;DNA integrity checkpoint signaling#GO:0031570;mitotic cell cycle process#GO:1903047;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;homologous recombination#GO:0035825;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;intracellular signal transduction#GO:0035556;organelle fission#GO:0048285;cell communication#GO:0007154;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982 catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000001703.3|UniProtKB=G3QH56 G3QH56 EFHD1 PTHR13025:SF5 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN D1 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000015172.3|UniProtKB=G3RGP9 G3RGP9 AGMAT PTHR11358:SF26 ARGINASE/AGMATINASE GUANIDINO ACID HYDROLASE, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;polyamine biosynthetic process#GO:0006596;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576 hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000027969.2|UniProtKB=G3SE92 G3SE92 PTHR15566:SF11 POM121-LIKE SUBFAMILY NOT NAMED GORGO|Ensembl=ENSGGOG00000014717.3|UniProtKB=G3R6Q3 G3R6Q3 PLCD3 PTHR10336:SF33 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-3 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;lipase activity#GO:0016298 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143 5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 GORGO|Ensembl=ENSGGOG00000011105.3|UniProtKB=G3RVB2 G3RVB2 PTHR10369:SF45 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN EL42-LIKE structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000002554.3|UniProtKB=A4K2R8 A4K2R8 LOC101131700 PTHR10547:SF6 SEMENOGELIN/SEMINAL VESICLE SECRETORY PROTEIN SEMENOGELIN-2 cellular developmental process#GO:0048869;cell maturation#GO:0048469;spermatogenesis#GO:0007283;developmental process#GO:0032502;sperm capacitation#GO:0048240;male gamete generation#GO:0048232;developmental maturation#GO:0021700;cellular process#GO:0009987;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;spermatid development#GO:0007286;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;developmental process involved in reproduction#GO:0003006 extracellular region#GO:0005576;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000012659.3|UniProtKB=G3RA94 G3RA94 RGL1 PTHR23113:SF199 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 1 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 Ras Pathway#P04393>RalGDS#P04551 GORGO|Ensembl=ENSGGOG00000027025.2|UniProtKB=G3S4V1 G3S4V1 FXYD2 PTHR14132:SF3 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000002926.3|UniProtKB=A0A2I2ZVX9 A0A2I2ZVX9 SRP54 PTHR11564:SF40 SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54 RNA binding#GO:0003723;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;signal sequence receptor activity#GO:0005048;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein targeting#GO:0006605;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;localization within membrane#GO:0051668 cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000041351.1|UniProtKB=A0A2I2ZH22 A0A2I2ZH22 PTHR47462:SF1 VESICLE-ASSOCIATED MEMBRANE PROTEIN 5 VESICLE-ASSOCIATED MEMBRANE PROTEIN 5 establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016423.3|UniProtKB=G3SHT0 G3SHT0 ENDOU PTHR12439:SF40 PLACENTAL PROTEIN 11-RELATED URIDYLATE-SPECIFIC ENDORIBONUCLEASE catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 post-transcriptional gene silencing#GO:0016441;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000011498.3|UniProtKB=A0A2I2ZC19 A0A2I2ZC19 RUBCN PTHR45971:SF3 PHOX (PX) DOMAIN-CONTAINING PROTEIN RUN DOMAIN BECLIN-1-INTERACTING AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 biological regulation#GO:0065007;regulation of protein-containing complex disassembly#GO:0043244;regulation of metabolic process#GO:0019222;negative regulation of macroautophagy#GO:0016242;regulation of localization#GO:0032879;regulation of macroautophagy#GO:0016241;negative regulation of autophagy#GO:0010507;regulation of transport#GO:0051049;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of autophagosome maturation#GO:1901096;regulation of endocytosis#GO:0030100;regulation of cellular component organization#GO:0051128;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of cellular component organization#GO:0051129;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of catabolic process#GO:0009895 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 GORGO|Ensembl=ENSGGOG00000005701.4|UniProtKB=G3QSF6 G3QSF6 FNDC3A PTHR13817:SF65 TITIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 3A-RELATED structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000023737.2|UniProtKB=A0A2I2YTW8 A0A2I2YTW8 PTHR24410:SF33 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000010078.3|UniProtKB=G3R3N0 G3R3N0 PKD1L1 PTHR10877:SF145 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-1-LIKE PROTEIN 1 passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 detection of mechanical stimulus#GO:0050982;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;response to mechanical stimulus#GO:0009612;response to stimulus#GO:0050896;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000004013.3|UniProtKB=G3QN31 G3QN31 ETNK1 PTHR22603:SF91 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000003957.3|UniProtKB=A0A2I2ZEQ0 A0A2I2ZEQ0 HIF1A PTHR23043:SF7 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA HYPOXIA-INDUCIBLE FACTOR 1-ALPHA double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;cellular response to hypoxia#GO:0071456;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;chemical homeostasis#GO:0048878;regulation of gene expression#GO:0010468;cellular homeostasis#GO:0019725;response to hypoxia#GO:0001666;intracellular chemical homeostasis#GO:0055082;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 Angiogenesis#P00005>HIF-1#P00214;Hypoxia response via HIF activation#P00030>HIF-1alpha#P00818;VEGF signaling pathway#P00056>HIF-1#P01401 GORGO|Ensembl=ENSGGOG00000015576.3|UniProtKB=G3RHS1 G3RHS1 DDX20 PTHR47958:SF89 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX20-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;macromolecular conformation isomerase activity#GO:0120543 protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;SMN complex#GO:0032797;cellular anatomical structure#GO:0110165;Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000009338.3|UniProtKB=G3R1P0 G3R1P0 KLF7 PTHR23235:SF77 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 7 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000028237.2|UniProtKB=G3RM83 G3RM83 LOC101151489 PTHR48018:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AP2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000006328.3|UniProtKB=G3QU03 G3QU03 TULP2 PTHR16517:SF24 TUBBY-RELATED TUBBY-RELATED PROTEIN 2 macromolecule localization#GO:0033036;localization#GO:0051179;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000006012.3|UniProtKB=G3QT71 G3QT71 LTA PTHR11471:SF31 TUMOR NECROSIS FACTOR FAMILY MEMBER LYMPHOTOXIN-ALPHA receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870;Apoptosis signaling pathway#P00006>TNF#P00259 GORGO|Ensembl=ENSGGOG00000005243.3|UniProtKB=G3QR90 G3QR90 UBE2L6 PTHR24068:SF43 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN_ISG15-CONJUGATING ENZYME E2 L6 ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>UbcH8#P01223 GORGO|Ensembl=ENSGGOG00000007508.3|UniProtKB=G3QX19 G3QX19 ADAMTS15 PTHR13723:SF39 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 15 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000025221.2|UniProtKB=G3S4R7 G3S4R7 PABIR2 PTHR22227:SF1 FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1 PABIR FAMILY MEMBER 2 enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;protein serine/threonine phosphatase inhibitor activity#GO:0004865;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000004561.3|UniProtKB=G3QPH7 G3QPH7 RREB1 PTHR46451:SF1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000040443.1|UniProtKB=A0A2I2ZU57 A0A2I2ZU57 PTHR45684:SF22 RE74312P SMALL MONOMERIC GTPASE catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003 intracellular organelle#GO:0043229;coated membrane#GO:0048475;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000001859.3|UniProtKB=G3SFN1 G3SFN1 STEAP1B PTHR14239:SF9 DUDULIN-RELATED STEAP FAMILY MEMBER 1B oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722;catalytic activity#GO:0003824;ferric-chelate reductase activity#GO:0000293 transition metal ion transport#GO:0000041;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 reductase#PC00198 GORGO|Ensembl=ENSGGOG00000012467.3|UniProtKB=G3R9S4 G3R9S4 EFCAB7 PTHR46819:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7 positive regulation of biological process#GO:0048518;regulation of protein localization to membrane#GO:1905475;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;cilium#GO:0005929;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000013707.3|UniProtKB=A0A2I2Z0U1 A0A2I2Z0U1 C2CD2 PTHR21119:SF7 C2 DOMAIN-CONTAINING PROTEIN C2 DOMAIN-CONTAINING PROTEIN 2 GORGO|Ensembl=ENSGGOG00000000530.3|UniProtKB=G3QE38 G3QE38 INPP5D PTHR46051:SF3 SH2 DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 1 positive regulation of cell differentiation#GO:0045597;positive regulation of leukocyte activation#GO:0002696;positive regulation of cell development#GO:0010720;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;regulation of B cell activation#GO:0050864;positive regulation of immune system process#GO:0002684;negative regulation of cell communication#GO:0010648;regulation of bone resorption#GO:0045124;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of myeloid cell differentiation#GO:0045637;regulation of lymphocyte activation#GO:0051249;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;positive regulation of developmental process#GO:0051094;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;positive regulation of cell activation#GO:0050867;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of bone remodeling#GO:0046850;regulation of tissue remodeling#GO:0034103;positive regulation of lymphocyte activation#GO:0051251;regulation of hemopoiesis#GO:1903706;regulation of immune response#GO:0050776;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of multicellular organismal process#GO:0051241 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000016606.3|UniProtKB=A0A2I2YV71 A0A2I2YV71 LUC7L2 PTHR12375:SF28 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN LUC7-LIKE 2-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA splice site recognition#GO:0006376;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA splicing, via transesterification reactions#GO:0000375 spliceosomal complex#GO:0005681;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114 GORGO|Ensembl=ENSGGOG00000039447.1|UniProtKB=A0A2I2YTF2 A0A2I2YTF2 PTHR23267:SF501 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 2-11 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000014609.3|UniProtKB=A0A2I2YS83 A0A2I2YS83 ZSCAN2 PTHR23226:SF469 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000001039.3|UniProtKB=G3QFF4 G3QFF4 DCAF1 PTHR13129:SF6 VPRBP PROTEIN-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 1 binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;DNA-binding transcription factor binding#GO:0140297;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;kinase activity#GO:0016301;nuclear estrogen receptor binding#GO:0030331;transferase activity#GO:0016740;nuclear receptor binding#GO:0016922;histone kinase activity#GO:0035173;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transcription factor binding#GO:0008134;catalytic activity, acting on a protein#GO:0140096 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000005166.3|UniProtKB=G3QR30 G3QR30 ZFYVE1 PTHR46624:SF3 AGAP002036-PA ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 1 lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular component organization or biogenesis#GO:0071840;lipid droplet organization#GO:0034389;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cellular process#GO:0009987;lipid storage#GO:0019915;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009811.3|UniProtKB=G3R2X0 G3R2X0 PTHR20931:SF3 TETRATRICOPEPTIDE REPEAT PROTEIN 30 INTRAFLAGELLAR TRANSPORT PROTEIN 70A binding#GO:0005488;protein-containing complex binding#GO:0044877 microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810 cilium#GO:0005929;intracellular organelle#GO:0043229;intraciliary transport particle#GO:0030990;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;cytoplasmic microtubule#GO:0005881;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080 GORGO|Ensembl=ENSGGOG00000005844.3|UniProtKB=G3QST1 G3QST1 PASD1 PTHR46055:SF5 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT CIRCADIAN CLOCK PROTEIN PASD1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;rhythmic process#GO:0048511;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000010249.3|UniProtKB=G3R413 G3R413 NDUFA4L2 PTHR14256:SF5 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE HYPOXIA ASSOCIATED SUBUNIT FA4L2 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000016972.3|UniProtKB=G3RRH0 G3RRH0 EPN2 PTHR12276:SF50 EPSIN/ENT-RELATED EPSIN-2 protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;phospholipid binding#GO:0005543;binding#GO:0005488 receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;endosome#GO:0005768;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle#GO:0030136;plasma membrane#GO:0005886;vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000000076.3|UniProtKB=G3QCX3 G3QCX3 LEPR PTHR23036:SF109 CYTOKINE RECEPTOR LEPTIN RECEPTOR cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell population proliferation#GO:0008284;response to peptide#GO:1901652;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000005276.3|UniProtKB=G3S6Z6 G3S6Z6 NCOA2 PTHR10684:SF2 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 2 transcription coactivator activity#GO:0003713;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription coregulator activity#GO:0003712;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to hormone#GO:0009725;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 GORGO|Ensembl=ENSGGOG00000023040.2|UniProtKB=G3RWK0 G3RWK0 LOC101129360 PTHR26453:SF626 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010242.3|UniProtKB=A0A2I2YPK6 A0A2I2YPK6 PDPN PTHR47390:SF1 PODOPLANIN PODOPLANIN regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cell migration#GO:0016477;regulation of cell adhesion#GO:0030155;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cell-cell adhesion#GO:0022409;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of platelet aggregation#GO:0090330;regulation of platelet activation#GO:0010543;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cell-cell adhesion#GO:0022407;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of cell activation#GO:0050865;positive regulation of cell adhesion#GO:0045785;regulation of biological process#GO:0050789 GORGO|Ensembl=ENSGGOG00000004568.3|UniProtKB=A0A2I2Y652 A0A2I2Y652 IFT20 PTHR31978:SF3 INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;localization#GO:0051179;organelle assembly#GO:0070925;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271 ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GORGO|Gene=FUT1|UniProtKB=Q9TUD4 Q9TUD4 FUT1 PTHR11927:SF4 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE GALACTOSIDE ALPHA-(1,2)-FUCOSYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000009114.3|UniProtKB=G3R156 G3R156 LOC101144264 PTHR24286:SF101 CYTOCHROME P450 26 CYTOCHROME P450 26A1 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;regulation of hormone levels#GO:0010817;central nervous system development#GO:0007417;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;animal gross anatomical part developmental process#GO:0160108;terpenoid metabolic process#GO:0006721;anatomical structure development#GO:0048856;isoprenoid metabolic process#GO:0006720;system development#GO:0048731;regulation of biological quality#GO:0065008;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;hormone metabolic process#GO:0042445;monocarboxylic acid catabolic process#GO:0072329;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;metabolic process#GO:0008152;developmental process#GO:0032502;lipid metabolic process#GO:0006629;multicellular organism development#GO:0007275;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101 oxygenase#PC00177 GORGO|Ensembl=ENSGGOG00000016871.3|UniProtKB=G3RL28 G3RL28 RBFOX1 PTHR15597:SF52 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000034947.2|UniProtKB=G3SKE2 G3SKE2 NELL1 PTHR24042:SF2 NEL HOMOLOG PROTEIN KINASE C-BINDING PROTEIN NELL1 protein binding#GO:0005515;glycosaminoglycan binding#GO:0005539;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201 positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of cell differentiation#GO:0045595 extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000003814.3|UniProtKB=G3QMK5 G3QMK5 PSCA PTHR16983:SF1 UPAR/LY6 DOMAIN-CONTAINING PROTEIN PROSTATE STEM CELL ANTIGEN binding#GO:0005488;signaling receptor binding#GO:0005102;acetylcholine receptor regulator activity#GO:0030548;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;neurotransmitter receptor regulator activity#GO:0099602;protein binding#GO:0005515 response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000008820.3|UniProtKB=A0A2I2ZTN5 A0A2I2ZTN5 EXOC7 PTHR12542:SF41 EXOCYST COMPLEX PROTEIN EXO70 EXOCYST COMPLEX COMPONENT 7 transport#GO:0006810;secretion by cell#GO:0032940;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;exocyst#GO:0000145;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000007245.3|UniProtKB=G3QWD2 G3QWD2 S100A6 PTHR11639:SF80 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A6 cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061;calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000007065.3|UniProtKB=G3QVX2 G3QVX2 LSMEM2 PTHR37333:SF1 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 2 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 2 GORGO|Ensembl=ENSGGOG00000005344.3|UniProtKB=G3QRH8 G3QRH8 FBXO8 PTHR10663:SF372 GUANYL-NUCLEOTIDE EXCHANGE FACTOR F-BOX ONLY PROTEIN 8 guanyl-nucleotide exchange factor#PC00113 GORGO|Ensembl=ENSGGOG00000003079.3|UniProtKB=G3QKQ1 G3QKQ1 CAPN11 PTHR10183:SF322 CALPAIN CALPAIN-11 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 GORGO|Ensembl=ENSGGOG00000026428.2|UniProtKB=G3SAG3 G3SAG3 LOC129524776 PTHR20981:SF42 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000003866.3|UniProtKB=G3QMP9 G3QMP9 PSTK PTHR20873:SF0 L-SERYL-TRNA(SEC) KINASE L-SERYL-TRNA(SEC) KINASE RNA binding#GO:0003723;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 GORGO|Ensembl=ENSGGOG00000025035.2|UniProtKB=G3RZJ5 G3RZJ5 XKR4 PTHR16024:SF16 XK-RELATED PROTEIN XK-RELATED PROTEIN 4 regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;lipid localization#GO:0010876;endocytosis#GO:0006897;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;cellular component organization#GO:0016043;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;membrane invagination#GO:0010324;endomembrane system organization#GO:0010256;cellular process#GO:0009987;anatomical structure development#GO:0048856;localization#GO:0051179;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cell death#GO:0008219;programmed cell death#GO:0012501;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;phagocytosis#GO:0006909;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;macromolecule localization#GO:0033036 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000005588.3|UniProtKB=G3QS54 G3QS54 LOXHD1 PTHR45901:SF8 PROTEIN CBG12474 LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1 sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501;system process#GO:0003008 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;actin-based cell projection#GO:0098858;membraneless organelle#GO:0043228;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;stereocilium#GO:0032420;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000016109.3|UniProtKB=G3RJ44 G3RJ44 SYT16 PTHR46129:SF4 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN-16 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000017139.3|UniProtKB=G3RLS5 G3RLS5 LOC101143194 PTHR45615:SF1 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-7 macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 anatomical structure development#GO:0048856;system development#GO:0048731;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;actin-mediated cell contraction#GO:0070252;circulatory system development#GO:0072359;striated muscle contraction#GO:0006941;heart process#GO:0003015;muscle system process#GO:0003012;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;heart contraction#GO:0060047;developmental process#GO:0032502;muscle contraction#GO:0006936;multicellular organismal process#GO:0032501;heart development#GO:0007507;blood circulation#GO:0008015;cellular process#GO:0009987;actin filament-based movement#GO:0030048 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 GORGO|Ensembl=ENSGGOG00000003427.3|UniProtKB=G3QLL0 G3QLL0 BEAN1 PTHR36464:SF1 PROTEIN BEAN1 PROTEIN BEAN1 GORGO|Ensembl=ENSGGOG00000024712.2|UniProtKB=G3SJV7 G3SJV7 GLUL PTHR20852:SF45 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968;Glutamine glutamate conversion#P02745>Glutamine synthase#P04483 GORGO|Ensembl=ENSGGOG00000013324.3|UniProtKB=A0A2I2Z6N3 A0A2I2Z6N3 STEEP1 PTHR46355:SF1 UPF0428 PROTEIN CXORF56 STING ER EXIT PROTEIN endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;Golgi vesicle transport#GO:0048193;endoplasmic reticulum membrane organization#GO:0090158;intracellular transport#GO:0046907 GORGO|Ensembl=ENSGGOG00000040244.1|UniProtKB=G3S6E6 G3S6E6 LOC101125479 PTHR46179:SF6 ZINC FINGER PROTEIN ZINC FINGER X-LINKED PROTEIN ZXDA transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000012569.3|UniProtKB=G3RA13 G3RA13 SLC2A6 PTHR48021:SF59 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 6 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014832.3|UniProtKB=G3RFU7 G3RFU7 PTHR10881:SF44 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 6A-RELATED organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi stack#GO:0005795;cis-Golgi network#GO:0005801;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;Golgi cis cisterna#GO:0000137;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000001717.3|UniProtKB=G3QH68 G3QH68 PRR12 PTHR14709:SF1 GLUTAMINE AND SERINE-RICH PROTEIN 1-RELATED PROLINE-RICH PROTEIN 12 GORGO|Ensembl=ENSGGOG00000005700.3|UniProtKB=A0A2I2YCE1 A0A2I2YCE1 CLEC1B PTHR46490:SF2 C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 1 MEMBER B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;developmental process#GO:0032502;hemopoiesis#GO:0030097;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;myeloid cell differentiation#GO:0030099;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000040538.1|UniProtKB=A0A2I2ZXC6 A0A2I2ZXC6 PTHR46254:SF11 PROTEIN GVQW1-RELATED SECRETED PROTEIN GORGO|Ensembl=ENSGGOG00000000282.3|UniProtKB=G3S199 G3S199 PLAAT2 PTHR13943:SF33 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 2 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;transferase activity#GO:0016740;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000036475.1|UniProtKB=A0A2I2Y961 A0A2I2Y961 PTHR12884:SF16 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000004052.3|UniProtKB=A0A2I2ZMD2 A0A2I2ZMD2 DDB1 PTHR10644:SF27 DNA REPAIR/RNA PROCESSING CPSF FAMILY DNA DAMAGE-BINDING PROTEIN 1 DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000011203.3|UniProtKB=G3R6I0 G3R6I0 EPB41L4A PTHR23280:SF4 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4A actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 GORGO|Ensembl=ENSGGOG00000000986.3|UniProtKB=A0A2I2ZVQ6 A0A2I2ZVQ6 HOMER1 PTHR10918:SF3 HOMER HOMER PROTEIN HOMOLOG 1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of localization#GO:0032879;regulation of transport#GO:0051049;cell surface receptor signaling pathway#GO:0007166;regulation of monoatomic ion transport#GO:0043269;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279 Metabotropic glutamate receptor group I pathway#P00041>Homer#P01058 GORGO|Ensembl=ENSGGOG00000000835.3|UniProtKB=G3QEW9 G3QEW9 REEP2 PTHR12300:SF29 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;microtubule binding#GO:0008017;G protein-coupled receptor binding#GO:0001664;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;cytoplasmic microtubule#GO:0005881;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;endoplasmic reticulum tubular network#GO:0071782;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000015246.3|UniProtKB=G3RGW5 G3RGW5 PADI4 PTHR10837:SF24 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE TYPE-4 histone modifying activity#GO:0140993;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000001783.3|UniProtKB=G3RBD7 G3RBD7 FOLH1 PTHR10404:SF36 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000004515.3|UniProtKB=G3QD32 G3QD32 PTHR24393:SF166 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 771 DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Gene=1OKO_GORGO|UniProtKB=P30388 P30388 PTHR16675:SF256 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN H-RELATED protein binding#GO:0005515;peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488;signaling receptor binding#GO:0005102 response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000013871.3|UniProtKB=G3RDD3 G3RDD3 DCST1 PTHR21041:SF17 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE DCST1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 sperm-egg recognition#GO:0035036;sexual reproduction#GO:0019953;cell recognition#GO:0008037;cell-cell recognition#GO:0009988;single fertilization#GO:0007338;cellular process#GO:0009987;fertilization#GO:0009566;reproductive process#GO:0022414 acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000023442.2|UniProtKB=G3RMG2 G3RMG2 FOXS1 PTHR11829:SF370 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN S1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 GORGO|Ensembl=ENSGGOG00000027638.2|UniProtKB=A0A2I2Z7S2 A0A2I2Z7S2 CCDC110 PTHR32083:SF32 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 110 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226 structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000006993.3|UniProtKB=A0A2I2ZXJ0 A0A2I2ZXJ0 FBXL15 PTHR13318:SF179 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 15 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 GORGO|Ensembl=ENSGGOG00000024325.2|UniProtKB=G3SE58 G3SE58 DSPP PTHR47819:SF1 DENTIN SIALOPHOSPHOPROTEIN DENTIN SIALOPHOSPHOPROTEIN protein-containing complex binding#GO:0044877;collagen binding#GO:0005518;binding#GO:0005488 anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;animal organ development#GO:0048513;anatomical structure formation involved in morphogenesis#GO:0048646;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;odontogenesis of dentin-containing tooth#GO:0042475;cell differentiation#GO:0030154;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;animal organ morphogenesis#GO:0009887;odontogenesis#GO:0042476;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000025764.2|UniProtKB=G3S981 G3S981 SLC25A19 PTHR24089:SF59 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER organophosphate ester transmembrane transporter activity#GO:0015605;quaternary ammonium group transmembrane transporter activity#GO:0015651;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;cellular process#GO:0009987;vitamin transport#GO:0051180;organophosphate ester transport#GO:0015748 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000036799.1|UniProtKB=G3RYG6 G3RYG6 INSL4 PTHR12004:SF3 RELAXIN EARLY PLACENTA INSULIN-LIKE PEPTIDE intercellular signal molecule#PC00207;peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000010405.3|UniProtKB=G3R4E7 G3R4E7 CFAP73 PTHR21683:SF9 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 73 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000025442.2|UniProtKB=G3RWK9 G3RWK9 PTHR12138:SF161 PRIMATE-EXPANDED PROTEIN FAMILY SECRETED PROTEIN GORGO|Ensembl=ENSGGOG00000022705.2|UniProtKB=A0A2I2YQU7 A0A2I2YQU7 UTP11 PTHR12838:SF0 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000004641.3|UniProtKB=G3QPP7 G3QPP7 CEP126 PTHR31191:SF4 CENTROSOMAL PROTEIN CEP126 CENTROSOMAL PROTEIN OF 126 KDA cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cytoplasmic microtubule organization#GO:0031122;cellular component organization#GO:0016043;cilium assembly#GO:0060271;supramolecular fiber organization#GO:0097435;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925 microtubule cytoskeleton#GO:0015630;ciliary base#GO:0097546;intracellular membraneless organelle#GO:0043232;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;midbody#GO:0030496;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000005760.3|UniProtKB=G3QSJ8 G3QSJ8 HES7 PTHR10985:SF84 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-7 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 GORGO|Ensembl=ENSGGOG00000025988.2|UniProtKB=G3SD17 G3SD17 SPINT4 PTHR47898:SF1 KUNITZ-TYPE PROTEASE INHIBITOR 4 KUNITZ-TYPE PROTEASE INHIBITOR 4 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000041163.1|UniProtKB=A0A2I2YB18 A0A2I2YB18 ZIK1 PTHR24377:SF688 IP01015P-RELATED ZINC FINGER PROTEIN INTERACTING WITH RIBONUCLEOPROTEIN K sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000009194.3|UniProtKB=G3R1C8 G3R1C8 PTHR16524:SF2 CELL DEATH REGULATOR AVEN CELL DEATH REGULATOR AVEN negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of mitotic cell cycle#GO:0045930;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987 GORGO|Ensembl=ENSGGOG00000026174.2|UniProtKB=G3SHM7 G3SHM7 PTHR18860:SF65 14-3-3 PROTEIN 14-3-3 DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000039462.1|UniProtKB=A0A2I2ZDY1 A0A2I2ZDY1 ANKZF1 PTHR16036:SF2 ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 TRNA ENDONUCLEASE ANKZF1 RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 gene expression#GO:0010467;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;translational elongation#GO:0006414;metabolic process#GO:0008152;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;rescue of stalled cytosolic ribosome#GO:0072344;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;translation#GO:0006412;protein catabolic process#GO:0030163 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000008904.3|UniProtKB=G3RTH3 G3RTH3 FAM13C PTHR15904:SF19 FAM13 PROTEIN FAM13C GORGO|Ensembl=ENSGGOG00000009261.3|UniProtKB=G3R1H9 G3R1H9 APOH PTHR19325:SF549 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING BETA-2-GLYCOPROTEIN 1 complement component#PC00078;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000042419.1|UniProtKB=A0A2I2YW10 A0A2I2YW10 LOC101147473 PTHR24281:SF318 STEROID 21-HYDROXYLASE-RELATED STEROID 21-HYDROXYLASE steroid hydroxylase activity#GO:0008395;binding#GO:0005488;tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;steroid biosynthetic process#GO:0006694;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 hydroxylase#PC00122 GORGO|Ensembl=ENSGGOG00000010743.3|UniProtKB=G3R5B3 G3R5B3 NEDD1 PTHR44414:SF1 PROTEIN NEDD1 PROTEIN NEDD1 protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;cellular component organization or biogenesis#GO:0071840;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815 GORGO|Ensembl=ENSGGOG00000009569.3|UniProtKB=G3R2A6 G3R2A6 GRIA3 PTHR18966:SF151 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 3 molecular transducer activity#GO:0060089;channel activity#GO:0015267;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 dendritic spine#GO:0043197;postsynapse#GO:0098794;neuron spine#GO:0044309;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;neuron projection#GO:0043005;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;transporter complex#GO:1990351;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;dendrite#GO:0030425;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>Glu3#P01016 GORGO|Ensembl=ENSGGOG00000007653.3|UniProtKB=G3QXE8 G3QXE8 MYO1E PTHR13140:SF341 MYOSIN UNCONVENTIONAL MYOSIN-IE microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 transport#GO:0006810;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897 actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 GORGO|Ensembl=ENSGGOG00000026343.2|UniProtKB=G3SGM5 G3SGM5 LOC101125840 PTHR11875:SF36 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 2 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000040667.1|UniProtKB=A0A2I2ZK28 A0A2I2ZK28 MXI1 PTHR11969:SF13 MAX DIMERIZATION, MAD MAX-INTERACTING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000011456.3|UniProtKB=G3R744 G3R744 TM4SF5 PTHR14198:SF4 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 5 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000024800.2|UniProtKB=A0A2I2ZRK1 A0A2I2ZRK1 TMEM154 PTHR36526:SF1 TRANSMEMBRANE PROTEIN 154 TRANSMEMBRANE PROTEIN 154 GORGO|Ensembl=ENSGGOG00000011958.3|UniProtKB=A0A2I2YBE8 A0A2I2YBE8 MAP2K4 PTHR48013:SF29 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 non-receptor serine/threonine protein kinase#PC00167 Oxidative stress response#P00046>MKK4#P01138;Ras Pathway#P04393>MKK4/7#P04565;p38 MAPK pathway#P05918>MKK4#P06034;Huntington disease#P00029>MAPKK4#P00787;FAS signaling pathway#P00020>MKK4#P00610;CCKR signaling map#P06959>MAP2K4#P07074;EGF receptor signaling pathway#P00018>MKK4,7#P00555;FGF signaling pathway#P00021>MKK4,7#P00637;Apoptosis signaling pathway#P00006>SEK1#P00266;Integrin signalling pathway#P00034>MEK#P00925;Angiogenesis#P00005>JNKK1#P00199;Huntington disease#P00029>SEK-1#P00792 GORGO|Ensembl=ENSGGOG00000007188.3|UniProtKB=G3QW88 G3QW88 FNDC7 PTHR47135:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 GORGO|Ensembl=ENSGGOG00000026021.2|UniProtKB=A0A2I2YTY3 A0A2I2YTY3 PTHR11205:SF37 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 RNA binding#GO:0003723;structural molecule activity#GO:0005198;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202;translational protein#PC00263 GORGO|Ensembl=ENSGGOG00000014158.3|UniProtKB=G3RE45 G3RE45 INF2 PTHR46345:SF8 INVERTED FORMIN-2 INVERTED FORMIN-2 GORGO|Ensembl=ENSGGOG00000009861.3|UniProtKB=G3R317 G3R317 LOC101128237 PTHR19944:SF86 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN protein-containing complex binding#GO:0044877;binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684 cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 GORGO|Ensembl=ENSGGOG00000015874.3|UniProtKB=G3RIH9 G3RIH9 NEMP2 PTHR13598:SF3 AT07567P-RELATED NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 2 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000043953.1|UniProtKB=A0A2I2ZQK0 A0A2I2ZQK0 PTHR10876:SF2 ZINC FINGER PROTEIN ZPR1 ZINC FINGER ZPR1-TYPE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;protein binding#GO:0005515 protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 GORGO|Ensembl=ENSGGOG00000009275.3|UniProtKB=G3R1I7 G3R1I7 EPOP PTHR23187:SF1 FLJ44216 PROTEIN-RELATED ELONGIN BC AND POLYCOMB REPRESSIVE COMPLEX 2-ASSOCIATED PROTEIN cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694 GORGO|Ensembl=ENSGGOG00000007948.3|UniProtKB=G3QY45 G3QY45 RHOJ PTHR24072:SF17 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOJ GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;response to stimulus#GO:0050896;transport#GO:0006810;actin filament organization#GO:0007015;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020;small GTPase#PC00208 Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507;EGF receptor signaling pathway#P00018>Rac#P00564 GORGO|Ensembl=ENSGGOG00000043550.1|UniProtKB=G3RSD7 G3RSD7 HMGN4 PTHR23087:SF27 NONHISTONE CHROMOSOMAL PROTEIN HMG DRESDEN PROSTATE CARCINOMA PROTEIN 2-RELATED binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000025461.2|UniProtKB=G3RR99 G3RR99 PTHR11732:SF420 ALDO/KETO REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 reductase#PC00198;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000026220.2|UniProtKB=G3S7C3 G3S7C3 SERPINF2 PTHR11461:SF20 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-2-ANTIPLASMIN molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240;positive regulation of coagulation#GO:0050820;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of coagulation#GO:0050818 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Plasminogen activating cascade#P00050>alpha2 antiplasmin#P01264;Blood coagulation#P00011>alpha2-antiplasmin#P00428 GORGO|Ensembl=ENSGGOG00000003973.3|UniProtKB=A0A2I2Y338 A0A2I2Y338 GCSAML PTHR35351:SF1 GERMINAL CENTER-ASSOCIATED SIGNALING AND MOTILITY-LIKE PROTEIN GERMINAL CENTER-ASSOCIATED SIGNALING AND MOTILITY-LIKE PROTEIN GORGO|Ensembl=ENSGGOG00000008132.3|UniProtKB=G3SFB1 G3SFB1 OAS1 PTHR11258:SF13 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;adenylyltransferase activity#GO:0070566;double-stranded RNA binding#GO:0003725;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;biological regulation#GO:0065007;response to other organism#GO:0051707;immune response#GO:0006955;cell communication#GO:0007154;response to virus#GO:0009615;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;antiviral innate immune response#GO:0140374;cellular response to stimulus#GO:0051716;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;response to peptide#GO:1901652;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789 membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;organelle lumen#GO:0043233;cytosol#GO:0005829;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;nucleotidyltransferase#PC00174 GORGO|Ensembl=ENSGGOG00000015291.3|UniProtKB=G3RH14 G3RH14 NUP188 PTHR31431:SF1 NUCLEOPORIN NUP188 HOMOLOG NUCLEOPORIN NUP188 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913 nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006943.3|UniProtKB=G3QVM3 G3QVM3 PRPF4 PTHR19846:SF5 WD40 REPEAT PROTEIN U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP4 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000003932.3|UniProtKB=G3QMW2 G3QMW2 CPNE2 PTHR10857:SF3 COPINE COPINE-2 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 response to calcium ion#GO:0051592;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to metal ion#GO:0010038 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 GORGO|Ensembl=ENSGGOG00000010939.3|UniProtKB=G3RTK2 G3RTK2 GATM PTHR10488:SF1 GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 GORGO|Ensembl=ENSGGOG00000039764.1|UniProtKB=Q66S60 Q66S60 MBL2 PTHR24024:SF34 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A MANNOSE-BINDING PROTEIN C signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 positive regulation of cellular component organization#GO:0051130;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of endocytosis#GO:0030100;immune effector process#GO:0002252;chemical homeostasis#GO:0048878;humoral immune response#GO:0006959;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;positive regulation of transport#GO:0051050;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;regulation of immune response#GO:0050776;response to external biotic stimulus#GO:0043207;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to external stimulus#GO:0009605;defense response#GO:0006952;multicellular organismal-level homeostasis#GO:0048871;innate immune response#GO:0045087;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of endocytosis#GO:0045807;multicellular organismal process#GO:0032501;immune response#GO:0006955;complement activation#GO:0006956;positive regulation of cellular process#GO:0048522 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 surfactant#PC00212;structural protein#PC00211 GORGO|Ensembl=ENSGGOG00000002147.3|UniProtKB=A0A2I2Y571 A0A2I2Y571 PTHR12570:SF1 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MAGNESIUM TRANSPORTER NIPA2 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;magnesium ion transport#GO:0015693;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000013910.3|UniProtKB=G3RDH4 G3RDH4 UACA PTHR24173:SF23 ANKYRIN REPEAT CONTAINING UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;negative regulation of signal transduction#GO:0009968;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;intrinsic apoptotic signaling pathway#GO:0097193;negative regulation of intracellular signal transduction#GO:1902532;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;apoptotic signaling pathway#GO:0097190;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;regulation of cell communication#GO:0010646;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000024270.2|UniProtKB=G3RNU5 G3RNU5 MITD1 PTHR21222:SF1 MIT DOMAIN-CONTAINING PROTEIN 1 MIT DOMAIN-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic cytokinetic process#GO:1902410;mitotic cell cycle process#GO:1903047;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;membrane organization#GO:0061024;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402 midbody#GO:0030496;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016049.3|UniProtKB=G3RIZ1 G3RIZ1 WNK4 PTHR13902:SF114 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK4 molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;protein kinase activity#GO:0004672;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;protein serine/threonine kinase activity#GO:0004674 regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;chemical homeostasis#GO:0048878 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000016381.3|UniProtKB=G3RJT1 G3RJT1 CFAP184 PTHR15654:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 184 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ciliary plasm#GO:0097014;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000016840.3|UniProtKB=G3RKZ8 G3RKZ8 YWHAE PTHR18860:SF67 14-3-3 PROTEIN 14-3-3 PROTEIN EPSILON binding#GO:0005488;protein binding#GO:0005515 regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624;Parkinson disease#P00049>14-3-3#P01238 GORGO|Ensembl=ENSGGOG00000011889.3|UniProtKB=A0A2I2Y1Y2 A0A2I2Y1Y2 ANP32E PTHR11375:SF26 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER enzyme inhibitor activity#GO:0004857;histone binding#GO:0042393;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000008799.3|UniProtKB=G3R0B8 G3R0B8 RAB8B PTHR47980:SF6 LD44762P RAS-RELATED PROTEIN RAB-8B vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;export from cell#GO:0140352;endocytic recycling#GO:0032456;secretion by cell#GO:0032940;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668 clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;trans-Golgi network transport vesicle#GO:0030140;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 GORGO|Ensembl=ENSGGOG00000002475.3|UniProtKB=G3QJ54 G3QJ54 GALNT5 PTHR11675:SF130 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 5 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000036719.1|UniProtKB=A0A2I2Y6L5 A0A2I2Y6L5 TRAPPC3L PTHR13048:SF1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3-LIKE PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 vesicle-mediated transport#GO:0016192;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;cis-Golgi network#GO:0005801;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;membrane#GO:0016020;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000014594.3|UniProtKB=G3RF82 G3RF82 GGA1 PTHR45905:SF4 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1 protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme binding#GO:0019899;binding#GO:0005488 vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;post-Golgi vesicle-mediated transport#GO:0006892;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;cellular process#GO:0009987;macromolecule localization#GO:0033036 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000006257.3|UniProtKB=G3QTV0 G3QTV0 MTMR3 PTHR10807:SF66 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR3 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;protein phosphatase binding#GO:0019903;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;hydrolase activity#GO:0016787;protein binding#GO:0005515 glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;lipid modification#GO:0030258;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 GORGO|Ensembl=ENSGGOG00000005943.3|UniProtKB=A0A2I2YG49 A0A2I2YG49 PTHR45870:SF3 TUBULIN MONOGLYCYLASE TTLL3 PROTEIN MONOGLYCYLASE TTLL8 catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;gamete generation#GO:0007276;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226 axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000008235.3|UniProtKB=G3QYV8 G3QYV8 CCNL2 PTHR10026:SF45 CYCLIN CYCLIN-L2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase modulator#PC00140;kinase activator#PC00138 GORGO|Ensembl=ENSGGOG00000001824.3|UniProtKB=G3SDE6 G3SDE6 BCLAF1 PTHR15268:SF4 THRAP3/BCLAF1 BCL-2-ASSOCIATED TRANSCRIPTION FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;DNA binding#GO:0003677 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000002596.3|UniProtKB=G3QJG8 G3QJG8 COL9A2 PTHR24023:SF906 COLLAGEN ALPHA COLLAGEN ALPHA-2(IX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 GORGO|Ensembl=ENSGGOG00000010983.3|UniProtKB=G3R5W8 G3R5W8 OCEL1 PTHR23288:SF15 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN_ELL DOMAIN-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;transcription by RNA polymerase II#GO:0006366;cell-cell junction organization#GO:0045216;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of transcription by RNA polymerase II#GO:0006357;snRNA transcription#GO:0009301;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;regulation of DNA-templated transcription elongation#GO:0032784 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;intracellular vesicle#GO:0097708;apical plasma membrane#GO:0016324;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;tight junction#GO:0070160;nuclear protein-containing complex#GO:0140513;cell junction#GO:0030054;apical junction complex#GO:0043296;apical part of cell#GO:0045177 general transcription factor#PC00259 GORGO|Ensembl=ENSGGOG00000022922.2|UniProtKB=Q0MQA1 Q0MQA1 NDUFA5 PTHR12653:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;metabolic process#GO:0008152 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000011109.3|UniProtKB=G3R688 G3R688 ADSS2 PTHR11846:SF13 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;ligase#PC00142 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 GORGO|Ensembl=ENSGGOG00000000115.3|UniProtKB=G3QD11 G3QD11 PTHR15720:SF13 GREB1-RELATED PROTEIN GREB1 anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;epithelium development#GO:0060429;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009 GORGO|Ensembl=ENSGGOG00000015938.3|UniProtKB=A0A2I2YUQ9 A0A2I2YUQ9 LOC101144919 PTHR43943:SF8 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 4-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 GORGO|Ensembl=ENSGGOG00000003653.3|UniProtKB=A0A2I2ZJH2 A0A2I2ZJH2 ALDOB PTHR11627:SF2 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE B lyase activity#GO:0016829;fructose-bisphosphate aldolase activity#GO:0004332;aldehyde-lyase activity#GO:0016832;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 aldolase#PC00044;lyase#PC00144 Glycolysis#P00024>Aldolase#P00679;Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959 GORGO|Ensembl=ENSGGOG00000015273.3|UniProtKB=G3RGY6 G3RGY6 DUSP9 PTHR10159:SF388 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 9 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000010185.3|UniProtKB=G3R3V1 G3R3V1 TMEM139 PTHR36294:SF1 TRANSMEMBRANE PROTEIN 139 TRANSMEMBRANE PROTEIN 139 GORGO|Ensembl=ENSGGOG00000001974.3|UniProtKB=G3QHV8 G3QHV8 GLI1 PTHR45718:SF2 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTION ACTIVATOR GLI1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;smoothened signaling pathway#GO:0007224;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 GORGO|Ensembl=ENSGGOG00000009919.3|UniProtKB=G3R368 G3R368 NUP35 PTHR21527:SF6 NUCLEOPORIN NUP35 NUCLEOPORIN NUP35 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;nucleus organization#GO:0006997;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;organelle organization#GO:0006996;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;nuclear pore organization#GO:0006999;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000043138.1|UniProtKB=A0A2I2YKC2 A0A2I2YKC2 PTHR45949:SF3 SORTING NEXIN-4 SORTING NEXIN-7 piecemeal microautophagy of the nucleus#GO:0034727;endocytic recycling#GO:0032456;catabolic process#GO:0009056;localization within membrane#GO:0051668;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;establishment of protein localization#GO:0045184;reticulophagy#GO:0061709;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;mitophagy#GO:0000423 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000000148.3|UniProtKB=G3QD43 G3QD43 TLL1 PTHR10127:SF860 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING TOLLOID-LIKE PROTEIN 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;metabolic process#GO:0008152;developmental process#GO:0032502;multicellular organismal process#GO:0032501;gene expression#GO:0010467;protein maturation#GO:0051604;regionalization#GO:0003002;biosynthetic process#GO:0009058;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;proteolysis#GO:0006508;pattern specification process#GO:0007389;primary metabolic process#GO:0044238;dorsal/ventral pattern formation#GO:0009953 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 TGF-beta signaling pathway#P00052>TGFbeta#P01286 GORGO|Ensembl=ENSGGOG00000028536.2|UniProtKB=G3SJR9 G3SJR9 TMED2 PTHR22811:SF50 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043;Golgi organization#GO:0007030 endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000012119.3|UniProtKB=G3R8U9 G3R8U9 ZNF391 PTHR24390:SF223 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 391 double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000009705.3|UniProtKB=A0A2I2Z472 A0A2I2Z472 ALDOC PTHR11627:SF3 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE C lyase activity#GO:0016829;fructose-bisphosphate aldolase activity#GO:0004332;aldehyde-lyase activity#GO:0016832;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 aldolase#PC00044;lyase#PC00144 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 GORGO|Ensembl=ENSGGOG00000042237.1|UniProtKB=G3QVN1 G3QVN1 LOC101125558 PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3B enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 GORGO|Ensembl=ENSGGOG00000042940.1|UniProtKB=G3SKH1 G3SKH1 LOC101142645 PTHR48001:SF142 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7A17 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000026308.2|UniProtKB=A0A2I2YP80 A0A2I2YP80 PFDN5 PTHR12674:SF6 PREFOLDIN SUBUNIT 5 PREFOLDIN SUBUNIT 5 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 GORGO|Ensembl=ENSGGOG00000022788.2|UniProtKB=G3RYJ3 G3RYJ3 NCR3LG1 PTHR23411:SF49 TAPASIN NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 LIGAND 1 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000017060.3|UniProtKB=G3RLJ9 G3RLJ9 PALMD PTHR46881:SF1 PALMDELPHIN PALMDELPHIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000002444.3|UniProtKB=G3QJ23 G3QJ23 SRSF4 PTHR23003:SF45 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE_ARGININE-RICH SPLICING FACTOR 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000004496.3|UniProtKB=G3SBL6 G3SBL6 IRX6 PTHR11211:SF11 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-6 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000016377.3|UniProtKB=G3RJT2 G3RJT2 PSMA8 PTHR11599:SF144 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA-TYPE 8 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;proteasome complex#GO:0000502;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 GORGO|Ensembl=ENSGGOG00000012706.3|UniProtKB=G3SHX3 G3SHX3 VCPKMT PTHR14614:SF158 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-LYSINE METHYLTRANSFERASE METTL21D lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000022443.2|UniProtKB=G3S619 G3S619 FDX1 PTHR23426:SF26 FERREDOXIN/ADRENODOXIN ADRENODOXIN, MITOCHONDRIAL generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152;electron transport chain#GO:0022900 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 GORGO|Ensembl=ENSGGOG00000010075.3|UniProtKB=A0A2I2YW08 A0A2I2YW08 CNGB3 PTHR45638:SF8 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL BETA-3 transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;guanyl nucleotide binding#GO:0019001;gated channel activity#GO:0022836;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;channel activity#GO:0015267 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 cation channel complex#GO:0034703;transporter complex#GO:1990351;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;transmembrane transporter complex#GO:1902495;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141;ion channel#PC00133 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 GORGO|Ensembl=ENSGGOG00000001491.3|UniProtKB=G3QGL2 G3QGL2 LOC101140427 PTHR26450:SF425 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000022573.2|UniProtKB=G3RVL0 G3RVL0 PTHR12001:SF73 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 isoprenoid metabolic process#GO:0006720;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000000195.3|UniProtKB=G3QD82 G3QD82 LOC101152957 PTHR48002:SF56 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K5 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000036133.1|UniProtKB=A0A2I2ZHS5 A0A2I2ZHS5 PTHR10489:SF689 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 2 immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular process#GO:0009987;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;neutrophil migration#GO:1990266;taxis#GO:0042330;granulocyte migration#GO:0097530;neutrophil chemotaxis#GO:0030593;regulation of biological process#GO:0050789;signaling#GO:0023052;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of biological quality#GO:0065008;immune response#GO:0006955;biological regulation#GO:0065007;cell migration#GO:0016477;leukocyte migration#GO:0050900;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;calcium-mediated signaling#GO:0019722;leukocyte chemotaxis#GO:0030595;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 GORGO|Ensembl=ENSGGOG00000014325.3|UniProtKB=A0A2I2YSN5 A0A2I2YSN5 MTCL2 PTHR15742:SF1 GIRDIN MICROTUBULE CROSS-LINKING FACTOR 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 regulation of metabolic process#GO:0019222;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of catabolic process#GO:0009894;biological regulation#GO:0065007 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000011067.3|UniProtKB=G3R648 G3R648 LPAR3 PTHR22750:SF21 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 3 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 GORGO|Ensembl=ENSGGOG00000016166.3|UniProtKB=G3SIW6 G3SIW6 SLC52A2 PTHR12929:SF1 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 nitrogen compound transport#GO:0071705;transport#GO:0006810;localization#GO:0051179;vitamin transport#GO:0051180;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 GORGO|Ensembl=ENSGGOG00000004190.3|UniProtKB=G3S250 G3S250 NES PTHR47051:SF1 NESTIN NESTIN signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;protein binding#GO:0005515 regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of organelle organization#GO:0033043;positive regulation of organelle organization#GO:0010638;regulation of protein depolymerization#GO:1901879;positive regulation of cellular component organization#GO:0051130 supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 GORGO|Ensembl=ENSGGOG00000017008.3|UniProtKB=A0A2I2Z1D5 A0A2I2Z1D5 PTHR46131:SF2 SD08549P MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER SLC25A51-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;purine nucleotide transmembrane transporter activity#GO:0015216 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000011411.3|UniProtKB=G3R703 G3R703 FOSL1 PTHR23351:SF6 FOS TRANSCRIPTION FACTOR-RELATED FOS-RELATED ANTIGEN 1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 GORGO|Ensembl=ENSGGOG00000010940.3|UniProtKB=G3R5S9 G3R5S9 FMO1 PTHR23023:SF154 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 biosynthetic process#GO:0009058;cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000040539.1|UniProtKB=A0A2I2Y4T4 A0A2I2Y4T4 ZNF230 PTHR24377:SF709 IP01015P-RELATED ZINC FINGER PROTEIN 230 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000023888.2|UniProtKB=A0A2I2Y8X4 A0A2I2Y8X4 PTHR48018:SF112 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000010584.3|UniProtKB=G3R4V8 G3R4V8 RDM1 PTHR31164:SF1 RAD52 MOTIF-CONTAINING PROTEIN 1 RAD52 MOTIF-CONTAINING PROTEIN 1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009273.3|UniProtKB=G3R1I9 G3R1I9 NEPRO PTHR34761:SF1 NUCLEOLUS AND NEURAL PROGENITOR PROTEIN RIBONUCLEASE MRP SUBUNIT P64 regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of signal transduction#GO:0009967;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;positive regulation of response to stimulus#GO:0048584;positive regulation of Notch signaling pathway#GO:0045747;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000037608.1|UniProtKB=A0A2I2ZY29 A0A2I2ZY29 TMEM91 PTHR14768:SF2 UPF0338 PROTEIN TRANSMEMBRANE PROTEIN 91 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000003293.3|UniProtKB=G3RNX5 G3RNX5 CEP192 PTHR16029:SF11 CENTROSOMAL PROTEIN OF 192 KDA CENTROSOMAL PROTEIN OF 192 KDA intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;protein localization to microtubule cytoskeleton#GO:0072698;mitotic spindle assembly#GO:0090307;macromolecule localization#GO:0033036;mitotic sister chromatid segregation#GO:0000070;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;mitotic cell cycle#GO:0000278;protein localization to organelle#GO:0033365;protein localization to centrosome#GO:0071539;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;protein localization to microtubule organizing center#GO:1905508;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;centrosome cycle#GO:0007098;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GORGO|Ensembl=ENSGGOG00000026071.2|UniProtKB=G3RT71 G3RT71 PTHR11544:SF68 COLD SHOCK DOMAIN CONTAINING PROTEINS Y BOX BINDING PROTEIN 1 LIKE 1 nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000004826.3|UniProtKB=G3RTY6 G3RTY6 CSNK1G1 PTHR11909:SF156 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 GORGO|Ensembl=ENSGGOG00000002965.3|UniProtKB=G3QKE2 G3QKE2 AKR1C3 PTHR11732:SF548 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000040908.1|UniProtKB=A0A2I2ZMC5 A0A2I2ZMC5 PTHR20371:SF1 ENOLASE-PHOSPHATASE E1 ENOLASE-PHOSPHATASE E1 phosphatase#PC00181;hydrolase#PC00121 GORGO|Ensembl=ENSGGOG00000037118.1|UniProtKB=A0A2I2Z6R8 A0A2I2Z6R8 HOXC4 PTHR45771:SF9 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-C4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;skeletal system development#GO:0001501;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;anterior/posterior pattern specification#GO:0009952;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 GORGO|Ensembl=ENSGGOG00000043801.1|UniProtKB=A0A2I2Z417 A0A2I2Z417 ARF6 PTHR11711:SF480 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 6 binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;protein localization to organelle#GO:0033365;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell leading edge#GO:0031252;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;ruffle#GO:0001726;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;recycling endosome#GO:0055037 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf6#P00919 GORGO|Ensembl=ENSGGOG00000011799.3|UniProtKB=G3R814 G3R814 CPSF2 PTHR45922:SF2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 GORGO|Ensembl=ENSGGOG00000007936.3|UniProtKB=G3QY36 G3QY36 HSPB7 PTHR46907:SF2 HEAT SHOCK PROTEIN BETA-7-RELATED HEAT SHOCK PROTEIN BETA-7 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000001607.3|UniProtKB=G3QGX0 G3QGX0 LOC101148349 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000007282.3|UniProtKB=G3QWG5 G3QWG5 FOXJ1 PTHR46805:SF1 FORKHEAD BOX PROTEIN J1 FORKHEAD BOX PROTEIN J1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 GORGO|Ensembl=ENSGGOG00000010713.3|UniProtKB=G3R577 G3R577 IGFBP1 PTHR11551:SF6 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515;growth factor binding#GO:0019838 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 PI3 kinase pathway#P00048>IGFBP1#G01543 GORGO|Ensembl=ENSGGOG00000014860.3|UniProtKB=G3S3Y2 G3S3Y2 TNS2 PTHR45734:SF1 TENSIN TENSIN-2 hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of cell communication#GO:0010648;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;anchoring junction#GO:0070161 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 GORGO|Ensembl=ENSGGOG00000038573.1|UniProtKB=A0A2I2YFI1 A0A2I2YFI1 DDA1 PTHR31879:SF6 DET1- AND DDB1-ASSOCIATED PROTEIN 1 DET1- AND DDB1-ASSOCIATED PROTEIN 1 positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 GORGO|Ensembl=ENSGGOG00000008848.3|UniProtKB=G3R0G6 G3R0G6 GCC1 PTHR23157:SF25 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 GORGO|Ensembl=ENSGGOG00000016765.3|UniProtKB=G3RKS5 G3RKS5 TRIM36 PTHR24099:SF18 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM36 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096 single fertilization#GO:0007338;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;acrosome reaction#GO:0007340;fertilization#GO:0009566;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000005106.3|UniProtKB=G3QQX7 G3QQX7 RMC1 PTHR12897:SF4 COLON CANCER-ASSOCIATED PROTEIN MIC1 REGULATOR OF MON1-CCZ1 COMPLEX structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794 late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;guanyl-nucleotide exchange factor complex#GO:0032045;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 GORGO|Ensembl=ENSGGOG00000026449.2|UniProtKB=G3RWY7 G3RWY7 CCL3 PTHR12015:SF183 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 26-RELATED leukocyte migration#GO:0050900;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;cellular process#GO:0009987;granulocyte migration#GO:0097530;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;chemotaxis#GO:0006935;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;locomotion#GO:0040011 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 GORGO|Ensembl=ENSGGOG00000005945.3|UniProtKB=G3QT10 G3QT10 MFSD6L PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000038872.1|UniProtKB=A0A2I2YLM5 A0A2I2YLM5 PTHR10797:SF43 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT POLY(A)-SPECIFIC RIBONUCLEASE nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;CCR4-NOT complex#GO:0030014 mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000015613.3|UniProtKB=G3RHV8 G3RHV8 PIK3AP1 PTHR16267:SF12 BANK1/PIK3AP1 FAMILY MEMBER PHOSPHOINOSITIDE 3-KINASE ADAPTER PROTEIN 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;phosphatidylinositol 3-kinase binding#GO:0043548 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000002729.3|UniProtKB=G3QJT5 G3QJT5 COPS6 PTHR10540:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 6 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513 translation initiation factor#PC00224 GORGO|Ensembl=ENSGGOG00000003181.3|UniProtKB=A0A2I2ZYD9 A0A2I2ZYD9 DDX3X PTHR47958:SF175 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX3X catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953 P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634 RNA helicase#PC00032 GORGO|Ensembl=ENSGGOG00000005407.3|UniProtKB=G3QRN2 G3QRN2 MMACHC PTHR31457:SF2 METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE C PROTEIN CYANOCOBALAMIN REDUCTASE _ ALKYLCOBALAMIN DEALKYLASE ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity, acting on metal ions#GO:0016722;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000000644.3|UniProtKB=G3QEE2 G3QEE2 PPM1F PTHR13832:SF233 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1F catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of actin filament bundle assembly#GO:0032231;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein phosphatase#PC00195 GORGO|Ensembl=ENSGGOG00000036928.1|UniProtKB=A0A2I2Y7L9 A0A2I2Y7L9 MAGEH1 PTHR11736:SF8 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN H1 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000008765.3|UniProtKB=G3R092 G3R092 SH3PXD2B PTHR15706:SF26 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2B enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;superoxide metabolic process#GO:0006801 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000040381.1|UniProtKB=A0A2I2ZYV2 A0A2I2ZYV2 PTHR10553:SF38 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;P granule#GO:0043186;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;U2 snRNP#GO:0005686;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;SMN-Sm protein complex#GO:0034719;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;U1 snRNP#GO:0005685;nucleus#GO:0005634;U12-type spliceosomal complex#GO:0005689;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U2-type prespliceosome#GO:0071004;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011 RNA splicing factor#PC00148 GORGO|Ensembl=ENSGGOG00000010108.3|UniProtKB=G3R3N6 G3R3N6 ABAT PTHR43206:SF1 AMINOTRANSFERASE 4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 Pyrimidine Metabolism#P02771>Aminotransferase#P03129;Aminobutyrate degradation#P02726>4-aminobutyrate aminotransferase#P02825;Gamma-aminobutyric acid synthesis#P04384>GABA aminotransferase#P04480 GORGO|Gene=WFDC5|UniProtKB=A4K2R4 A4K2R4 WFDC5 PTHR19441:SF39 WAP four-disulfide core domain protein WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 5 serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 GORGO|Ensembl=ENSGGOG00000038019.1|UniProtKB=A0A2I2ZQY4 A0A2I2ZQY4 RMND5A PTHR12170:SF5 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5A ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000009326.3|UniProtKB=G3R1P2 G3R1P2 HERC3 PTHR45622:SF18 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC3-RELATED catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000012157.3|UniProtKB=A0A2I2Z7Q0 A0A2I2Z7Q0 GEN1 PTHR11081:SF70 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE GEN HOMOLOG 1 nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;four-way junction DNA binding#GO:0000400;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;DNA binding#GO:0003677;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000016189.3|UniProtKB=G3RJA9 G3RJA9 KHNYN PTHR12876:SF28 N4BP1-RELATED PROTEIN KHNYN nuclease activity#GO:0004518;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008 nucleus#GO:0005634;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000023527.2|UniProtKB=G3RZ22 G3RZ22 ATP6V1F PTHR13861:SF2 VACUOLAR ATP SYNTHASE SUBUNIT F V-TYPE PROTON ATPASE SUBUNIT F membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP synthase#PC00002;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000002411.3|UniProtKB=G3QIZ9 G3QIZ9 SPATA16 PTHR47228:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 16 SPERMATOGENESIS-ASSOCIATED PROTEIN 16 spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;gamete generation#GO:0007276;male gamete generation#GO:0048232;reproductive process#GO:0022414 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GORGO|Ensembl=ENSGGOG00000040081.1|UniProtKB=A0A2I2YTA5 A0A2I2YTA5 SYNGR1 PTHR10838:SF7 SYNAPTOGYRIN SYNAPTOGYRIN-1 cellular process#GO:0009987;cellular component organization#GO:0016043;synaptic vesicle membrane organization#GO:0048499;endomembrane system organization#GO:0010256;export from cell#GO:0140352;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;transport#GO:0006810;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 cell junction#GO:0030054;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 GORGO|Ensembl=ENSGGOG00000002896.3|UniProtKB=G3QK79 G3QK79 ZBED3 PTHR35827:SF2 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 3 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 3 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 GORGO|Ensembl=ENSGGOG00000014861.3|UniProtKB=G3RFW9 G3RFW9 PTHR23226:SF432 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000022750.2|UniProtKB=G3RRU8 G3RRU8 ZNF14 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 670 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000027891.2|UniProtKB=G3S2H1 G3S2H1 NOL9 PTHR12755:SF3 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9 nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000012790.3|UniProtKB=G3RAL0 G3RAL0 PASK PTHR24346:SF51 MAP/MICROTUBULE AFFINITY-REGULATING KINASE PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;signaling#GO:0023052;regulation of carbohydrate biosynthetic process#GO:0043255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;negative regulation of cellular process#GO:0048523;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000001466.3|UniProtKB=G3S733 G3S733 YPEL5 PTHR13848:SF58 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 5 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 GORGO|Ensembl=ENSGGOG00000014955.3|UniProtKB=G3RG54 G3RG54 EGLN2 PTHR12907:SF6 EGL NINE HOMOLOG-RELATED PROLYL HYDROXYLASE EGLN2 cation binding#GO:0043169;metal ion binding#GO:0046872;dioxygenase activity#GO:0051213;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;ferrous iron binding#GO:0008198;catalytic activity#GO:0003824 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;response to hypoxia#GO:0001666;regulation of apoptotic process#GO:0042981 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 GORGO|Ensembl=ENSGGOG00000025795.2|UniProtKB=A0A2I2YTP1 A0A2I2YTP1 CRP PTHR45869:SF21 C-REACTIVE PROTEIN-RELATED C-REACTIVE PROTEIN low-density lipoprotein particle binding#GO:0030169;protein-lipid complex binding#GO:0071814;lipoprotein particle binding#GO:0071813;binding#GO:0005488;complement binding#GO:0001848;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 innate immune response#GO:0045087;defense response#GO:0006952;acute inflammatory response#GO:0002526;response to external stimulus#GO:0009605;immune system process#GO:0002376;inflammatory response#GO:0006954;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000016393.3|UniProtKB=G3RJV1 G3RJV1 EXTL1 PTHR11062:SF8 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 1 acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000016799.3|UniProtKB=G3RKV9 G3RKV9 NEIL3 PTHR22993:SF10 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 3 hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;DNA N-glycosylase activity#GO:0019104;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;base-excision repair#GO:0006284;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA glycosylase#PC00010 GORGO|Ensembl=ENSGGOG00000023000.1|UniProtKB=G3RWE6 G3RWE6 ND4L PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000025085.2|UniProtKB=G3RSF6 G3RSF6 LOC101147404 PTHR48018:SF58 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9I1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000027139.2|UniProtKB=G3RWH5 G3RWH5 PTHR48112:SF8 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B3 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 GORGO|Ensembl=ENSGGOG00000013518.3|UniProtKB=G3RCF7 G3RCF7 NMI PTHR15225:SF4 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN N-MYC-INTERACTOR intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000003099.3|UniProtKB=G3QKR7 G3QKR7 EXOSC1 PTHR12686:SF8 3'-5' EXORIBONUCLEASE CSL4-RELATED EXOSOME COMPLEX COMPONENT CSL4 cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;maturation of 5.8S rRNA#GO:0000460;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;rRNA processing#GO:0006364;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA metabolism protein#PC00031;exoribonuclease#PC00099 GORGO|Ensembl=ENSGGOG00000008036.3|UniProtKB=G3S4U7 G3S4U7 CHRNA1 PTHR18945:SF74 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;acetylcholine receptor activity#GO:0015464;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 muscle contraction#GO:0006936;transport#GO:0006810;system process#GO:0003008;establishment of localization#GO:0051234;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;acetylcholine receptor signaling pathway#GO:0095500;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;neuromuscular process#GO:0050905;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;membrane depolarization#GO:0051899;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;neuromuscular synaptic transmission#GO:0007274;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;nervous system process#GO:0050877;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;muscle system process#GO:0003012;skeletal muscle contraction#GO:0003009;signaling#GO:0023052;response to stimulus#GO:0050896 postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cell junction#GO:0030054;transporter complex#GO:1990351;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 GORGO|Ensembl=ENSGGOG00000012024.3|UniProtKB=A0A2I2YLY2 A0A2I2YLY2 LUZP1 PTHR23166:SF7 FILAMIN/GPBP-INTERACTING PROTEIN LEUCINE ZIPPER PROTEIN 1 protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630 GORGO|Ensembl=ENSGGOG00000001297.3|UniProtKB=G3QG29 G3QG29 TMEM72 PTHR28474:SF1 TRANSMEMBRANE PROTEIN 72 TRANSMEMBRANE PROTEIN 72 GORGO|Ensembl=ENSGGOG00000013016.3|UniProtKB=G3S727 G3S727 NRBF2 PTHR14964:SF5 NUCLEAR RECEPTOR BINDING FACTOR 2 NUCLEAR RECEPTOR-BINDING FACTOR 2 catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;metabolic process#GO:0008152;autophagy#GO:0006914;cellular process#GO:0009987 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000010607.3|UniProtKB=G3R4X8 G3R4X8 RANBP3L PTHR23138:SF88 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3-LIKE intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;protein export from nucleus#GO:0006611;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000015580.3|UniProtKB=G3S773 G3S773 GTPBP3 PTHR42714:SF9 TRNA MODIFICATION GTPASE GTPBP3 5-TAURINOMETHYLURIDINE-[TRNA] SYNTHASE SUBUNIT GTPB3, MITOCHONDRIAL biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;RNA methylation#GO:0001510;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000026020.2|UniProtKB=G3RQR8 G3RQR8 PTHR11753:SF45 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-2 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 GORGO|Ensembl=ENSGGOG00000003527.3|UniProtKB=G3S435 G3S435 IL2RA PTHR10573:SF0 INTERLEUKIN-2 RECEPTOR ALPHA CHAIN INTERLEUKIN-2 RECEPTOR SUBUNIT ALPHA transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;positive regulation of leukocyte activation#GO:0002696;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of leukocyte proliferation#GO:0070663;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of T cell activation#GO:0050863;response to cytokine#GO:0034097;positive regulation of T cell activation#GO:0050870;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;response to peptide#GO:1901652;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;regulation of lymphocyte activation#GO:0051249;positive regulation of T cell proliferation#GO:0042102;signaling#GO:0023052;positive regulation of leukocyte proliferation#GO:0070665;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cellular process#GO:0048522;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;cytokine-mediated signaling pathway#GO:0019221;positive regulation of lymphocyte proliferation#GO:0050671;positive regulation of lymphocyte activation#GO:0051251;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of cell adhesion#GO:0045785;cellular response to stimulus#GO:0051716;interleukin-2-mediated signaling pathway#GO:0038110;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of T cell proliferation#GO:0042129 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 GORGO|Ensembl=ENSGGOG00000044018.1|UniProtKB=A0A2I2ZH37 A0A2I2ZH37 LOC109024996 PTHR11096:SF0 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE ligase activity#GO:0016874;cyclase activity#GO:0009975;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 GORGO|Ensembl=ENSGGOG00000014770.3|UniProtKB=G3RFP1 G3RFP1 ELAPOR2 PTHR22727:SF3 PROTEIN CBG13728 ENDOSOME_LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR FAMILY MEMBER 2 regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of BMP signaling pathway#GO:0030510;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of BMP signaling pathway#GO:0030513 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GORGO|Ensembl=ENSGGOG00000041415.1|UniProtKB=A0A2I2Z2N3 A0A2I2Z2N3 SOWAHA PTHR14491:SF2 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHA Ubiquitin proteasome pathway#P00060>E2#P01491 GORGO|Ensembl=ENSGGOG00000036537.1|UniProtKB=A0A2I2YS59 A0A2I2YS59 TMOD3 PTHR10901:SF18 TROPOMODULIN TROPOMODULIN-3 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;cellular developmental process#GO:0048869;actin filament organization#GO:0007015;system process#GO:0003008;muscle contraction#GO:0006936;developmental process#GO:0032502;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692 contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 GORGO|Ensembl=ENSGGOG00000025721.2|UniProtKB=G3SI48 G3SI48 MFSD6 PTHR16172:SF43 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6 immune system process#GO:0002376;antigen processing and presentation#GO:0019882 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GORGO|Ensembl=ENSGGOG00000008280.3|UniProtKB=G3SAH9 G3SAH9 VSNL1 PTHR23055:SF101 CALCIUM BINDING PROTEINS VISININ-LIKE PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 calmodulin-related#PC00061 GORGO|Ensembl=ENSGGOG00000002580.3|UniProtKB=G3QJE6 G3QJE6 KIAA1143 PTHR31195:SF2 GEO02494P1 GEO02494P1 GORGO|Ensembl=ENSGGOG00000036368.1|UniProtKB=G3SAJ5 G3SAJ5 ZNF266 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000007355.3|UniProtKB=G3QWN6 G3QWN6 ADAMTS1 PTHR13723:SF40 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 1 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 GORGO|Ensembl=ENSGGOG00000004008.3|UniProtKB=G3QN30 G3QN30 DDHD2 PTHR23509:SF7 PA-PL1 PHOSPHOLIPASE FAMILY TRIACYLGLYCEROL HYDROLASE DDHD2 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;lipase activity#GO:0016298;triacylglycerol lipase activity#GO:0004806;carboxylic ester hydrolase activity#GO:0052689 coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 phospholipase#PC00186;metabolite interconversion enzyme#PC00262 GORGO|Ensembl=ENSGGOG00000002362.3|UniProtKB=G3QIV4 G3QIV4 B3GAT1 PTHR10896:SF21 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;hexosyltransferase activity#GO:0016758 carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000016815.3|UniProtKB=G3R5A3 G3R5A3 ZNF784 PTHR24393:SF56 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 784 transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000010294.3|UniProtKB=A0A2I2ZUK7 A0A2I2ZUK7 PRSS53 PTHR24276:SF61 POLYSERASE-RELATED SERINE PROTEASE 53 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 serine protease#PC00203;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000009183.3|UniProtKB=A0A2I2Z6V2 A0A2I2Z6V2 TCTN2 PTHR14611:SF6 TECTONIC FAMILY MEMBER TECTONIC-2 cellular component assembly#GO:0022607;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;signaling#GO:0023052;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;localization#GO:0051179;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;cilium organization#GO:0044782;organelle assembly#GO:0070925 membrane-bounded organelle#GO:0043227;cilium#GO:0005929;ciliary transition zone#GO:0035869;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 GORGO|Ensembl=ENSGGOG00000016749.3|UniProtKB=G3RKR2 G3RKR2 ARF5 PTHR11711:SF489 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 5 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 GORGO|Ensembl=ENSGGOG00000012062.3|UniProtKB=G3R8Q2 G3R8Q2 PPP1R8 PTHR23308:SF74 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE 1 enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;protein serine/threonine phosphatase inhibitor activity#GO:0004865;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;system development#GO:0048731;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;regulation of BMP signaling pathway#GO:0030510;axon development#GO:0061564;axon guidance#GO:0007411;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of BMP signaling pathway#GO:0030513;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 organelle lumen#GO:0043233;nuclear speck#GO:0016607;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 RNA splicing factor#PC00148 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 GORGO|Ensembl=ENSGGOG00000009879.3|UniProtKB=G3R339 G3R339 VASP PTHR11202:SF12 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER VASODILATOR-STIMULATED PHOSPHOPROTEIN binding#GO:0005488;protein binding#GO:0005515 actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;axon guidance#GO:0007411;positive regulation of cellular process#GO:0048522;actin polymerization or depolymerization#GO:0008154;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of anatomical structure size#GO:0090066;neuron differentiation#GO:0030182;positive regulation of cellular component biogenesis#GO:0044089;cell morphogenesis involved in neuron differentiation#GO:0048667;embryo development#GO:0009790;nervous system development#GO:0007399;organelle organization#GO:0006996;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;cellular developmental process#GO:0048869;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;tissue development#GO:0009888;regulation of actin polymerization or depolymerization#GO:0008064;tube development#GO:0035295;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;regulation of actin filament organization#GO:0110053;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;system development#GO:0048731;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of supramolecular fiber organization#GO:1902903;tube morphogenesis#GO:0035239;embryonic morphogenesis#GO:0048598;cell projection morphogenesis#GO:0048858;morphogenesis of an epithelium#GO:0002009;plasma membrane bounded cell projection morphogenesis#GO:0120039;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of organelle organization#GO:0010638;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535 cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>VASP#P00934;Axon guidance mediated by netrin#P00009>Ena#P00361;Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516 GORGO|Ensembl=ENSGGOG00000036623.1|UniProtKB=A0A2I2Y8B7 A0A2I2Y8B7 PTHR23267:SF402 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-39-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 GORGO|Ensembl=ENSGGOG00000015957.3|UniProtKB=G3RIQ5 G3RIQ5 KPNA1 PTHR23316:SF3 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-5 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signal transduction#GO:0007165;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;synaptic signaling#GO:0099536;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cell communication#GO:0007154;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000027144.2|UniProtKB=G3RNN7 G3RNN7 PTHR12400:SF78 INOSITOL POLYPHOSPHATE KINASE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase#PC00137 GORGO|Ensembl=ENSGGOG00000010843.4|UniProtKB=A0A2I2ZM06 A0A2I2ZM06 PTHR45911:SF2 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;regulation of secretion by cell#GO:1903530;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of secretion#GO:0051046 transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 GORGO|Ensembl=ENSGGOG00000007415.3|UniProtKB=G3QWT6 G3QWT6 HUS1B PTHR12900:SF3 MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 CHECKPOINT PROTEIN HUS1B regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;response to stress#GO:0006950;DNA replication checkpoint signaling#GO:0000076;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786;DNA recombination#GO:0006310;metabolic process#GO:0008152;signaling#GO:0023052;mitotic DNA replication checkpoint signaling#GO:0033314;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;telomere maintenance#GO:0000723;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;recombinational repair#GO:0000725;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;negative regulation of cell cycle G2/M phase transition#GO:1902750;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;biological regulation#GO:0065007;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;telomere organization#GO:0032200;regulation of G2/M transition of mitotic cell cycle#GO:0010389;sexual reproduction#GO:0019953 site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009 GORGO|Ensembl=ENSGGOG00000016561.3|UniProtKB=A0A2I2Z3V9 A0A2I2Z3V9 GALNT14 PTHR11675:SF8 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 14 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 GORGO|Ensembl=ENSGGOG00000000552.3|UniProtKB=G3QE56 G3QE56 SAMD3 PTHR47302:SF1 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 3 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 3 GORGO|Ensembl=ENSGGOG00000011684.3|UniProtKB=G3R7P9 G3R7P9 PTHR15035:SF11 CORTICOLIBERIN/UROCORTIN UROCORTIN binding#GO:0005488;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of system process#GO:0044057;regulation of transport#GO:0051049;regulation of localization#GO:0032879;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of hormone secretion#GO:0046883;cell communication#GO:0007154;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;positive regulation of multicellular organismal process#GO:0051240;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell body#GO:0044297 intercellular signal molecule#PC00207;peptide hormone#PC00179 GORGO|Ensembl=ENSGGOG00000003540.3|UniProtKB=G3QLV7 G3QLV7 AKR7A2 PTHR43625:SF12 AFLATOXIN B1 ALDEHYDE REDUCTASE AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 metabolic process#GO:0008152;secondary metabolic process#GO:0019748;cellular process#GO:0009987;detoxification#GO:0098754;response to toxic substance#GO:0009636;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to chemical#GO:0042221 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000013856.3|UniProtKB=G3S4A9 G3S4A9 JMJD8 PTHR12480:SF35 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN 8 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000025799.2|UniProtKB=G3S7U7 G3S7U7 CCDC192 PTHR38580:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 192 COILED-COIL DOMAIN-CONTAINING PROTEIN 192 GORGO|Ensembl=ENSGGOG00000005349.3|UniProtKB=G3QRI4 G3QRI4 CD1B PTHR16675:SF130 MHC CLASS I-RELATED T-CELL SURFACE GLYCOPROTEIN CD1B lipid binding#GO:0008289;antigen binding#GO:0003823;binding#GO:0005488 positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000005584.3|UniProtKB=G3QS43 G3QS43 PTHR22937:SF233 E3 UBIQUITIN-PROTEIN LIGASE RNF165 E3 UBIQUITIN-PROTEIN LIGASE ARK2C ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of BMP signaling pathway#GO:0030513;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;proteasomal protein catabolic process#GO:0010498;generation of neurons#GO:0048699;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;neuron projection guidance#GO:0097485;ubiquitin-dependent protein catabolic process#GO:0006511;neurogenesis#GO:0022008;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of BMP signaling pathway#GO:0030510;axon guidance#GO:0007411;axon development#GO:0061564;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000012744.3|UniProtKB=G3RAG1 G3RAG1 BTNL9 PTHR24100:SF162 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000003263.3|UniProtKB=G3R2B1 G3R2B1 LOC101136398 PTHR15251:SF3 TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731;brain development#GO:0007420;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;head development#GO:0060322 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 GORGO|Ensembl=ENSGGOG00000008729.3|UniProtKB=G3R054 G3R054 UBD PTHR47731:SF1 UBIQUITIN D UBIQUITIN D protein-containing complex binding#GO:0044877;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;modification-dependent protein catabolic process#GO:0019941;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;innate immune response#GO:0045087;macromolecule metabolic process#GO:0043170;defense response#GO:0006952;ubiquitin-dependent protein catabolic process#GO:0006511;response to external stimulus#GO:0009605;response to tumor necrosis factor#GO:0034612;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;post-translational protein modification#GO:0043687;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;regulation of programmed cell death#GO:0043067;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to type II interferon#GO:0034341;cellular process#GO:0009987;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;protein ubiquitination#GO:0016567 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000038937.1|UniProtKB=A0A2I2YC64 A0A2I2YC64 PTHR14964:SF3 NUCLEAR RECEPTOR BINDING FACTOR 2 NUCLEAR RECEPTOR BINDING FACTOR 2 catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;metabolic process#GO:0008152;autophagy#GO:0006914;cellular process#GO:0009987 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 GORGO|Ensembl=ENSGGOG00000005022.3|UniProtKB=A0A2I2YBL0 A0A2I2YBL0 CD99L2 PTHR15076:SF12 CD99/MIC2 PROTEIN RELATED CD99 ANTIGEN-LIKE PROTEIN 2 GORGO|Ensembl=ENSGGOG00000006512.3|UniProtKB=G3QUG6 G3QUG6 ZIC2 PTHR19818:SF27 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 2 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000036136.1|UniProtKB=A0A2I2Z6D3 A0A2I2Z6D3 PTHR23268:SF28 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 27 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 GORGO|Ensembl=ENSGGOG00000038929.1|UniProtKB=A0A2I2YRF2 A0A2I2YRF2 PTHR10445:SF0 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIFbeta#P00667;Transcription regulation by bZIP transcription factor#P00055>TFIIFbeta#P01396 GORGO|Ensembl=ENSGGOG00000013945.3|UniProtKB=G3RDK9 G3RDK9 WWC3 PTHR14791:SF25 BOMB/KIRA PROTEINS PROTEIN WWC3 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 cell migration#GO:0016477;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of macromolecule metabolic process#GO:0060255;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000004982.3|UniProtKB=G3QQL7 G3QQL7 PLCZ1 PTHR10336:SF29 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ZETA-1 lipase activity#GO:0016298;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 cellular process#GO:0009987;single fertilization#GO:0007338;reproductive process#GO:0022414;fertilization#GO:0009566;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell activation#GO:0001775;sexual reproduction#GO:0019953;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of biological quality#GO:0065008 membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143 5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 GORGO|Ensembl=ENSGGOG00000008129.3|UniProtKB=G3QYK5 G3QYK5 KCNK13 PTHR11003:SF57 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 13 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000011062.3|UniProtKB=A0A2I2YDW6 A0A2I2YDW6 DYRK4 PTHR24058:SF136 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000015570.3|UniProtKB=G3RHR4 G3RHR4 INO80D PTHR16198:SF2 INO80 COMPLEX SUBUNIT D INO80 COMPLEX SUBUNIT D intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000011775.3|UniProtKB=G3R7Y7 G3R7Y7 MAP3K11 PTHR23257:SF757 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GORGO|Ensembl=ENSGGOG00000004608.3|UniProtKB=G3QPM3 G3QPM3 PPAT PTHR11907:SF20 AMIDOPHOSPHORIBOSYLTRANSFERASE AMIDOPHOSPHORIBOSYLTRANSFERASE pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753 metabolite interconversion enzyme#PC00262;transferase#PC00220 De novo purine biosynthesis#P02738>Amidophosphoribosyl transferase#P02905 GORGO|Ensembl=ENSGGOG00000015283.3|UniProtKB=G3RUL4 G3RUL4 ZW10 PTHR12205:SF0 CENTROMERE/KINETOCHORE PROTEIN ZW10 CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;localization#GO:0051179;cell communication#GO:0007154;organelle fission#GO:0048285;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular signal transduction#GO:0035556;negative regulation of chromosome organization#GO:2001251;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346;establishment of localization#GO:0051234;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;cellular component organization#GO:0016043;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of cell cycle#GO:0045786;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;Golgi vesicle transport#GO:0048193;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;cellular localization#GO:0051641;nuclear division#GO:0000280;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;vesicle-mediated transport#GO:0016192;organelle organization#GO:0006996;negative regulation of sister chromatid segregation#GO:0033046;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048 intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;spindle#GO:0005819;vesicle tethering complex#GO:0099023;endoplasmic reticulum protein-containing complex#GO:0140534;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 GORGO|Ensembl=ENSGGOG00000041055.1|UniProtKB=A0A2I2YSC3 A0A2I2YSC3 PTHR15124:SF20 SELENOPROTEIN W SELENOPROTEIN W immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;multicellular organismal-level homeostasis#GO:0048871;cellular process#GO:0009987;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;myeloid cell differentiation#GO:0030099;hemopoiesis#GO:0030097;homeostatic process#GO:0042592;cell development#GO:0048468 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GORGO|Ensembl=ENSGGOG00000025493.2|UniProtKB=G3SG79 G3SG79 PTHR24381:SF110 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 614 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000000708.3|UniProtKB=A0A2I2Y9R3 A0A2I2Y9R3 CHD5 PTHR45623:SF6 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD5 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;histone binding#GO:0042393;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;DNA binding#GO:0003677 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000007023.3|UniProtKB=A0A2I2ZWW2 A0A2I2ZWW2 PTHR10838:SF32 SYNAPTOGYRIN MARVEL DOMAIN-CONTAINING PROTEIN regulated exocytosis#GO:0045055;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;exocytosis#GO:0006887;synaptic vesicle membrane organization#GO:0048499;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;export from cell#GO:0140352 intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;presynapse#GO:0098793;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cell junction#GO:0030054 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 GORGO|Ensembl=ENSGGOG00000002450.3|UniProtKB=G3S877 G3S877 SERAC1 PTHR48182:SF2 PROTEIN SERAC1 PROTEIN SERAC1 GORGO|Ensembl=ENSGGOG00000015616.3|UniProtKB=A0A2I2YBM4 A0A2I2YBM4 SEZ6L2 PTHR45656:SF2 PROTEIN CBR-CLEC-78 SEIZURE 6-LIKE PROTEIN 2 developmental process#GO:0032502;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;cellular process#GO:0009987;cellular component organization#GO:0016043;nervous system development#GO:0007399;developmental maturation#GO:0021700;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501 cell body#GO:0044297;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GORGO|Ensembl=ENSGGOG00000003459.3|UniProtKB=G3QLN7 G3QLN7 TIMM13 PTHR19338:SF107 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM13 mitochondrial transport#GO:0006839;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial protein import pathway#GO:7770058;mitochondrion organization#GO:0007005;protein insertion into mitochondrial inner membrane#GO:0045039;membrane organization#GO:0061024;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907 mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial envelope#GO:0005740;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial intermembrane space#GO:0005758 GORGO|Ensembl=ENSGGOG00000013975.3|UniProtKB=A0A2I2YUH8 A0A2I2YUH8 M1AP PTHR28642:SF1 MEIOSIS 1 ARREST PROTEIN MEIOSIS 1 ARREST PROTEIN spermatogenesis#GO:0007283;chromosome segregation#GO:0007059;developmental process#GO:0032502;meiotic cell cycle#GO:0051321;meiotic chromosome segregation#GO:0045132;chromosome separation#GO:0051304;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;male meiotic nuclear division#GO:0007140;male gamete generation#GO:0048232;sexual reproduction#GO:0019953;nuclear division#GO:0000280;multicellular organismal reproductive process#GO:0048609;organelle fission#GO:0048285;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;reproductive process#GO:0022414;gamete generation#GO:0007276 GORGO|Ensembl=ENSGGOG00000004612.3|UniProtKB=G3QPM6 G3QPM6 TAGAP PTHR23179:SF26 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED T-CELL ACTIVATION RHO GTPASE-ACTIVATING PROTEIN enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 GORGO|Ensembl=ENSGGOG00000012447.3|UniProtKB=G3R9P9 G3R9P9 ABHD15 PTHR10794:SF39 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD15 protease#PC00190;serine protease#PC00203 GORGO|Ensembl=ENSGGOG00000011467.3|UniProtKB=G3R752 G3R752 AP5S1 PTHR16120:SF0 AP-5 COMPLEX SUBUNIT SIGMA-1 AP-5 COMPLEX SUBUNIT SIGMA-1 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 AP-type membrane coat adaptor complex#GO:0030119;lytic vacuole#GO:0000323;cytosol#GO:0005829;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;vesicle#GO:0031982;lysosome#GO:0005764;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GORGO|Ensembl=ENSGGOG00000037530.1|UniProtKB=A0A2I2YW41 A0A2I2YW41 RPL19 PTHR10722:SF48 60S RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN EL19 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 GORGO|Ensembl=ENSGGOG00000022360.2|UniProtKB=G3RMN7 G3RMN7 GABARAPL1 PTHR10969:SF30 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 1 ubiquitin-like protein ligase binding#GO:0044389;GABA receptor binding#GO:0050811;phospholipid binding#GO:0005543;ubiquitin protein ligase binding#GO:0031625;enzyme binding#GO:0019899;binding#GO:0005488;signaling receptor binding#GO:0005102;lipid binding#GO:0008289;protein binding#GO:0005515 cellular response to stress#GO:0033554;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to nutrient levels#GO:0031669;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macroautophagy#GO:0016236;cellular component assembly#GO:0022607 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;autophagosome#GO:0005776;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 GORGO|Ensembl=ENSGGOG00000001112.3|UniProtKB=A0A2I2YE47 A0A2I2YE47 ATP11C PTHR24092:SF38 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IG intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;recycling endosome#GO:0055037;endoplasmic reticulum#GO:0005783 transporter#PC00227;primary active transporter#PC00068 GORGO|Ensembl=ENSGGOG00000004252.3|UniProtKB=G3RPG3 G3RPG3 LOC101133052 PTHR19944:SF99 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ BETA 1 CHAIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823;protein-containing complex binding#GO:0044877 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;regulation of immune response#GO:0050776;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell adhesion#GO:0045785 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773 major histocompatibility complex protein#PC00149 GORGO|Ensembl=ENSGGOG00000002639.3|UniProtKB=G3QJK4 G3QJK4 DUSP5 PTHR10159:SF40 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 5 protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 regulation of MAPK cascade#GO:0043408;endoderm development#GO:0007492;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;embryo development#GO:0009790;endoderm formation#GO:0001706;formation of primary germ layer#GO:0001704;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;gastrulation#GO:0007369;signaling#GO:0023052;response to stimulus#GO:0050896;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;tissue development#GO:0009888;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;cell communication#GO:0007154;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 GORGO|Ensembl=ENSGGOG00000024139.2|UniProtKB=A0A2I2ZRC4 A0A2I2ZRC4 LOC101154255 PTHR26450:SF22 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B6 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000013477.3|UniProtKB=A0A2I2Z0W0 A0A2I2Z0W0 TNFRSF21 PTHR46921:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 regulation of B cell proliferation#GO:0030888;humoral immune response#GO:0006959;regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130;regulation of B cell activation#GO:0050864;regulation of mononuclear cell proliferation#GO:0032944;cellular process#GO:0009987;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;immune system process#GO:0002376;neuron apoptotic process#GO:0051402;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;apoptotic process#GO:0006915;regulation of multicellular organismal development#GO:2000026;response to stimulus#GO:0050896;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;negative regulation of cell activation#GO:0050866;negative regulation of cell population proliferation#GO:0008285;immune response#GO:0006955;negative regulation of cell adhesion#GO:0007162;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;adaptive immune response#GO:0002250;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;regulation of nervous system development#GO:0051960;negative regulation of multicellular organismal process#GO:0051241;programmed cell death#GO:0012501;cell death#GO:0008219;regulation of T cell proliferation#GO:0042129;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of developmental process#GO:0050793;negative regulation of leukocyte cell-cell adhesion#GO:1903038 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 GORGO|Ensembl=ENSGGOG00000012740.3|UniProtKB=G3RAF6 G3RAF6 AKR1A1 PTHR11732:SF385 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 GORGO|Ensembl=ENSGGOG00000023073.2|UniProtKB=G3RUJ1 G3RUJ1 GON7 PTHR37363:SF1 EKC/KEOPS COMPLEX SUBUNIT GON7 EKC_KEOPS COMPLEX SUBUNIT GON7 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 GORGO|Ensembl=ENSGGOG00000008916.3|UniProtKB=A0A2I2YUZ9 A0A2I2YUZ9 UBQLN4 PTHR10677:SF21 UBIQUILIN UBIQUILIN-4 protein binding#GO:0005515;binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 GORGO|Ensembl=ENSGGOG00000002217.3|UniProtKB=G3QIH3 G3QIH3 HOXA5 PTHR45659:SF10 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A5 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 GORGO|Ensembl=ENSGGOG00000026195.2|UniProtKB=G3S3Z3 G3S3Z3 GLRB PTHR18945:SF29 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT BETA extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride channel activity#GO:0005254;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 trans-synaptic signaling#GO:0099537;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220 synaptic membrane#GO:0097060;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590 ligand-gated ion channel#PC00141 GORGO|Ensembl=ENSGGOG00000043715.1|UniProtKB=A0A2I2YDN6 A0A2I2YDN6 KCND2 PTHR11537:SF265 VOLTAGE-GATED POTASSIUM CHANNEL A-TYPE VOLTAGE-GATED POTASSIUM CHANNEL KCND2 potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;action potential#GO:0001508;metal ion transport#GO:0030001 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;voltage-gated potassium channel complex#GO:0008076;cell junction#GO:0030054;transporter complex#GO:1990351;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell body#GO:0044297;dendritic spine#GO:0043197;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuronal cell body#GO:0043025;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;dendritic tree#GO:0097447;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241;ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000013562.3|UniProtKB=A0A2I2ZNF0 A0A2I2ZNF0 PRDM5 PTHR24376:SF247 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 624 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 GORGO|Ensembl=ENSGGOG00000015942.3|UniProtKB=G3RIP3 G3RIP3 LOC101150774 PTHR23150:SF37 SULFATASE MODIFYING FACTOR 1, 2 FORMYLGLYCINE-GENERATING ENZYME oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 GORGO|Ensembl=ENSGGOG00000044101.1|UniProtKB=G3QH78 G3QH78 PTHR10516:SF429 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1B catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853 regulation of biological process#GO:0050789;regulation of muscle system process#GO:0090257;protein folding#GO:0006457;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of muscle contraction#GO:0006937;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;regulation of heart contraction#GO:0008016;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cell communication#GO:0007154;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;calcium-mediated signaling#GO:0019722;macromolecule metabolic process#GO:0043170 sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 GORGO|Ensembl=ENSGGOG00000013612.3|UniProtKB=G3RCP4 G3RCP4 SCRT1 PTHR24388:SF60 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR SCRATCH 1 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 GORGO|Ensembl=ENSGGOG00000011992.3|UniProtKB=G3R8I2 G3R8I2 PTGER2 PTHR11866:SF8 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP2 SUBTYPE molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to hormone#GO:0009725;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to alcohol#GO:0097305;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to alcohol#GO:0097306;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of biological quality#GO:0065008;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 GORGO|Ensembl=ENSGGOG00000005287.3|UniProtKB=G3RTF8 G3RTF8 TMEM254 PTHR34104:SF3 TRANSMEMBRANE PROTEIN 254 TRANSMEMBRANE PROTEIN 254 GORGO|Gene=NDUFA2|UniProtKB=Q0MQ92 Q0MQ92 NDUFA2 PTHR12878:SF6 NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 2 respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 GORGO|Ensembl=ENSGGOG00000028434.2|UniProtKB=G3SC01 G3SC01 LOC101142817 PTHR22745:SF0 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of apoptotic process#GO:0043066;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 GORGO|Ensembl=ENSGGOG00000013209.3|UniProtKB=G3SBW3 G3SBW3 CLIC5 PTHR45476:SF4 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN 5 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;establishment of localization#GO:0051234 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 ion channel#PC00133 GORGO|Ensembl=ENSGGOG00000014345.3|UniProtKB=G3REK1 G3REK1 FAM161B PTHR21501:SF4 PROTEIN FAM-161 PROTEIN FAM161B plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 GORGO|Ensembl=ENSGGOG00000008972.3|UniProtKB=G3R0T0 G3R0T0 SLC44A4 PTHR12385:SF37 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 4 organophosphate ester transmembrane transporter activity#GO:0015605;quaternary ammonium group transmembrane transporter activity#GO:0015651;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;organophosphate ester transport#GO:0015748;vitamin transport#GO:0051180;cellular process#GO:0009987;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 GORGO|Ensembl=ENSGGOG00000006582.3|UniProtKB=G3QUN5 G3QUN5 MSL3 PTHR10880:SF55 MORTALITY FACTOR 4-LIKE PROTEIN MSL COMPLEX SUBUNIT 3 chromatin binding#GO:0003682;histone reader activity#GO:0140566;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 GORGO|Ensembl=ENSGGOG00000007040.3|UniProtKB=G3QVV3 G3QVV3 TMEM184B PTHR23423:SF28 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184B transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 GORGO|Ensembl=ENSGGOG00000024642.2|UniProtKB=G3S2T1 G3S2T1 CTSV PTHR12411:SF57 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L2 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 GORGO|Ensembl=ENSGGOG00000004449.3|UniProtKB=A0A2I2YRC3 A0A2I2YRC3 CPEB2 PTHR12566:SF8 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 2 translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730;translation factor activity#GO:0180051;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of translation#GO:0017148;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;neuron projection#GO:0043005;nucleus#GO:0005634;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 GORGO|Ensembl=ENSGGOG00000015659.4|UniProtKB=G3RI07 G3RI07 MAST2 PTHR24356:SF136 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 2 binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;microtubule binding#GO:0008017;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;tubulin binding#GO:0015631;transferase activity, transferring phosphorus-containing groups#GO:0016772;cytoskeletal protein binding#GO:0008092;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;signaling#GO:0023052 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 GORGO|Ensembl=ENSGGOG00000025117.2|UniProtKB=G3S4Q7 G3S4Q7 TRAV9-2 PTHR19367:SF43 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 9-2 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 GORGO|Ensembl=ENSGGOG00000014291.3|UniProtKB=G3REF2 G3REF2 LOC101143714 PTHR12155:SF43 SCHLAFEN SCHLAFEN FAMILY MEMBER 13 tRNA binding#GO:0000049;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 defense response#GO:0006952;response to external stimulus#GO:0009605;response to virus#GO:0009615;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to stress#GO:0006950;defense response to virus#GO:0051607;response to biotic stimulus#GO:0009607 endoribonuclease#PC00094 GORGO|Ensembl=ENSGGOG00000002427.3|UniProtKB=Q7YRP1 Q7YRP1 VN1R5 PTHR24062:SF174 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 5 binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197